-- dump date 20140619_042848 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002802314.1 226947223 7768234 157..1494 1 NC_012563.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1494 dnaA 7768234 dnaA Clostridium botulinum A2 str. Kyoto chromosomal replication initiation protein YP_002802314.1 157 D 536232 CDS YP_002802315.1 226947224 7766685 1757..2860 1 NC_012563.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2860 dnaN 7766685 dnaN Clostridium botulinum A2 str. Kyoto DNA polymerase III subunit beta YP_002802315.1 1757 D 536232 CDS YP_002802316.1 226947225 7766539 2879..3085 1 NC_012563.1 identified by match to protein family HMM PF01479; match to protein family HMM TIGR02988; S4 domain-containing protein 3085 7766539 CLM_0003 Clostridium botulinum A2 str. Kyoto S4 domain-containing protein YP_002802316.1 2879 D 536232 CDS YP_002802317.1 226947226 7765001 3164..4258 1 NC_012563.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4258 recF 7765001 recF Clostridium botulinum A2 str. Kyoto recombination protein F YP_002802317.1 3164 D 536232 CDS YP_002802318.1 226947227 7765810 4279..4542 1 NC_012563.1 hypothetical protein 4542 7765810 CLM_0005 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802318.1 4279 D 536232 CDS YP_002802319.1 226947228 7766255 4560..6473 1 NC_012563.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 6473 gyrB 7766255 gyrB Clostridium botulinum A2 str. Kyoto DNA gyrase subunit B YP_002802319.1 4560 D 536232 CDS YP_002802320.1 226947229 7768126 6499..9039 1 NC_012563.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 9039 gyrA 7768126 gyrA Clostridium botulinum A2 str. Kyoto DNA gyrase subunit A YP_002802320.1 6499 D 536232 CDS YP_002802321.1 226947230 7768171 14624..15076 1 NC_012563.1 hypothetical protein 15076 7768171 CLM_0015 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802321.1 14624 D 536232 CDS YP_002802322.1 226947231 7767205 15092..15613 1 NC_012563.1 identified by similarity to PDB:1J5Y_A; match to protein family HMM PF02829; match to protein family HMM PF08279; transcriptional regulator, biotin repressor family 15613 7767205 CLM_0016 Clostridium botulinum A2 str. Kyoto transcriptional regulator, biotin repressor family YP_002802322.1 15092 D 536232 CDS YP_002802323.1 226947232 7767277 15615..16778 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF04015; iron-sulfur cluster-binding protein 16778 7767277 CLM_0017 Clostridium botulinum A2 str. Kyoto iron-sulfur cluster-binding protein YP_002802323.1 15615 D 536232 CDS YP_002802324.1 226947233 7764686 16783..19464 1 NC_012563.1 identified by match to protein family HMM PF03699; hypothetical protein 19464 7764686 CLM_0018 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802324.1 16783 D 536232 CDS YP_002802325.1 226947234 7765535 19601..20377 1 NC_012563.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 20377 7765535 CLM_0019 Clostridium botulinum A2 str. Kyoto ErfK/YbiS/YcfS/YnhG family protein YP_002802325.1 19601 D 536232 CDS YP_002802326.1 226947235 7766909 20402..21799 1 NC_012563.1 identified by match to protein family HMM PF01266; match to protein family HMM PF04324; FAD-dependent family oxidoreductase 21799 7766909 CLM_0020 Clostridium botulinum A2 str. Kyoto FAD-dependent family oxidoreductase YP_002802326.1 20402 D 536232 CDS YP_002802327.1 226947236 7766883 21816..22169 1 NC_012563.1 identified by match to protein family HMM PF07892; hypothetical protein 22169 7766883 CLM_0021 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802327.1 21816 D 536232 CDS YP_002802328.1 226947237 7767757 22539..23819 1 NC_012563.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 23819 serS 7767757 serS Clostridium botulinum A2 str. Kyoto seryl-tRNA synthetase YP_002802328.1 22539 D 536232 CDS YP_002802329.1 226947238 7768195 complement(25001..25888) 1 NC_012563.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 25888 psd 7768195 psd Clostridium botulinum A2 str. Kyoto phosphatidylserine decarboxylase YP_002802329.1 25001 R 536232 CDS YP_002802330.1 226947239 7765965 complement(25991..27589) 1 NC_012563.1 identified by match to protein family HMM PF03109; hypothetical protein 27589 7765965 CLM_0029 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802330.1 25991 R 536232 CDS YP_002802331.1 226947240 7766247 complement(27665..27985) 1 NC_012563.1 hypothetical protein 27985 7766247 CLM_0030 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802331.1 27665 R 536232 CDS YP_002802332.1 226947241 7768172 28379..29941 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF07728; putative sensory box sigma-54 dependent transcriptional regulator 29941 7768172 CLM_0032 Clostridium botulinum A2 str. Kyoto putative sensory box sigma-54 dependent transcriptional regulator YP_002802332.1 28379 D 536232 CDS YP_002802333.1 226947242 7766996 30101..31303 1 NC_012563.1 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; methionine gamma-lyase 31303 megL 7766996 megL Clostridium botulinum A2 str. Kyoto methionine gamma-lyase YP_002802333.1 30101 D 536232 CDS YP_002802334.1 226947243 7767706 31427..31864 1 NC_012563.1 identified by match to protein family HMM PF00383; cytidine/deoxycytidylate deaminase family protein 31864 7767706 CLM_0034 Clostridium botulinum A2 str. Kyoto cytidine/deoxycytidylate deaminase family protein YP_002802334.1 31427 D 536232 CDS YP_002802335.1 226947244 7768129 32509..34134 1 NC_012563.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 34134 dnaX 7768129 dnaX Clostridium botulinum A2 str. Kyoto DNA polymerase III subunits gamma and tau YP_002802335.1 32509 D 536232 CDS YP_002802336.1 226947245 7764457 34199..34540 1 NC_012563.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 34540 7764457 CLM_0038 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802336.1 34199 D 536232 CDS YP_002802337.1 226947246 7764534 34573..35169 1 NC_012563.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 35169 recR 7764534 recR Clostridium botulinum A2 str. Kyoto recombination protein RecR YP_002802337.1 34573 D 536232 CDS YP_002802338.1 226947247 7766873 35226..35489 1 NC_012563.1 hypothetical protein 35489 7766873 CLM_0040 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802338.1 35226 D 536232 CDS YP_002802339.1 226947248 7767732 35639..35899 1 NC_012563.1 identified by similarity to SP:P24282; match to protein family HMM PF07441; match to protein family HMM TIGR02862; sigma-K factor processing regulatory protein BofA 35899 bofA 7767732 bofA Clostridium botulinum A2 str. Kyoto sigma-K factor processing regulatory protein BofA YP_002802339.1 35639 D 536232 CDS YP_002802340.1 226947249 7765108 36050..36742 1 NC_012563.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 36742 sfsA 7765108 sfsA Clostridium botulinum A2 str. Kyoto sugar fermentation stimulation protein A YP_002802340.1 36050 D 536232 CDS YP_002802341.1 226947250 7765116 36798..37286 1 NC_012563.1 identified by match to protein family HMM PF00293; NUDIX family hydrolase 37286 7765116 CLM_0043 Clostridium botulinum A2 str. Kyoto NUDIX family hydrolase YP_002802341.1 36798 D 536232 CDS YP_002802342.1 226947251 7767053 37404..38126 1 NC_012563.1 hypothetical protein 38126 7767053 CLM_0044 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802342.1 37404 D 536232 CDS YP_002802343.1 226947252 7764518 38260..39048 1 NC_012563.1 identified by match to protein family HMM PF00037; iron-sulfur cluster-binding protein 39048 7764518 CLM_0045 Clostridium botulinum A2 str. Kyoto iron-sulfur cluster-binding protein YP_002802343.1 38260 D 536232 CDS YP_002802344.1 226947253 7767330 39067..39228 1 NC_012563.1 hypothetical protein 39228 7767330 CLM_0046 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802344.1 39067 D 536232 CDS YP_002802345.1 226947254 7766721 39611..40315 1 NC_012563.1 identified by match to protein family HMM PF00899; thiF domain-containing protein 40315 7766721 CLM_0047 Clostridium botulinum A2 str. Kyoto thiF domain-containing protein YP_002802345.1 39611 D 536232 CDS YP_002802346.1 226947255 7767862 40398..41507 1 NC_012563.1 identified by match to protein family HMM PF07690; major facilitator superfamily protein 41507 7767862 CLM_0048 Clostridium botulinum A2 str. Kyoto major facilitator superfamily protein YP_002802346.1 40398 D 536232 CDS YP_002802347.1 226947256 7764480 41536..42480 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 42480 7764480 CLM_0049 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002802347.1 41536 D 536232 CDS YP_002802348.1 226947257 7768138 complement(45926..46381) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 46381 7768138 CLM_0051 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802348.1 45926 R 536232 CDS YP_002802349.1 226947258 7764977 complement(46455..47111) 1 NC_012563.1 hypothetical protein 47111 7764977 CLM_0052 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802349.1 46455 R 536232 CDS YP_002802350.1 226947259 7768205 complement(47963..48559) 1 NC_012563.1 identified by match to protein family HMM PF03167; uracil-DNA glycosylase family protein 48559 7768205 CLM_0056 Clostridium botulinum A2 str. Kyoto uracil-DNA glycosylase family protein YP_002802350.1 47963 R 536232 CDS YP_002802351.1 226947260 7768134 complement(52482..52937) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 52937 7768134 CLM_0058 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802351.1 52482 R 536232 CDS YP_002802352.1 226947261 7766531 complement(53011..53667) 1 NC_012563.1 hypothetical protein 53667 7766531 CLM_0059 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802352.1 53011 R 536232 CDS YP_002802353.1 226947262 7768220 54640..55203 1 NC_012563.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 55203 7768220 CLM_0063 Clostridium botulinum A2 str. Kyoto RNA polymerase factor sigma-70 YP_002802353.1 54640 D 536232 CDS YP_002802354.1 226947263 7764710 55200..56642 1 NC_012563.1 hypothetical protein 56642 7764710 CLM_0064 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802354.1 55200 D 536232 CDS YP_002802355.1 226947264 7768140 complement(60351..60806) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 60806 7768140 CLM_0066 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802355.1 60351 R 536232 CDS YP_002802356.1 226947265 7765392 complement(60880..61536) 1 NC_012563.1 hypothetical protein 61536 7765392 CLM_0067 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802356.1 60880 R 536232 CDS YP_002802357.1 226947266 7768179 62427..62567 1 NC_012563.1 hypothetical protein 62567 7768179 CLM_0072 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802357.1 62427 D 536232 CDS YP_002802358.1 226947267 7765093 62714..62995 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; hypothetical protein 62995 7765093 CLM_0073 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802358.1 62714 D 536232 CDS YP_002802359.1 226947268 7765973 63230..63388 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; protein DltD 63388 7765973 CLM_0074 Clostridium botulinum A2 str. Kyoto protein DltD YP_002802359.1 63230 D 536232 CDS YP_002802360.1 226947269 7765429 63465..63578 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 63578 7765429 CLM_0076 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802360.1 63465 D 536232 CDS YP_002802361.1 226947270 7768141 complement(67356..67811) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 67811 7768141 CLM_0078 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802361.1 67356 R 536232 CDS YP_002802362.1 226947271 7765632 complement(67885..68541) 1 NC_012563.1 hypothetical protein 68541 7765632 CLM_0079 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802362.1 67885 R 536232 CDS YP_002802363.1 226947272 7768187 69312..70055 1 NC_012563.1 identified by match to protein family HMM PF00639; peptidil-prolyl isomerase family protein 70055 7768187 CLM_0083 Clostridium botulinum A2 str. Kyoto peptidil-prolyl isomerase family protein YP_002802363.1 69312 D 536232 CDS YP_002802364.1 226947273 7768146 75661..76404 1 NC_012563.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 76404 7768146 CLM_0089 Clostridium botulinum A2 str. Kyoto NAD-dependent deacetylase YP_002802364.1 75661 D 536232 CDS YP_002802365.1 226947274 7768203 complement(76590..77498) 1 NC_012563.1 identified by match to protein family HMM PF02016; LD-carboxypeptidase family protein 77498 7768203 CLM_0091 Clostridium botulinum A2 str. Kyoto LD-carboxypeptidase family protein YP_002802365.1 76590 R 536232 CDS YP_002802366.1 226947275 7764401 complement(77534..78475) 1 NC_012563.1 identified by match to protein family HMM PF01544; transporter, CorA metal ion transporter family 78475 7764401 CLM_0092 Clostridium botulinum A2 str. Kyoto transporter, CorA metal ion transporter family YP_002802366.1 77534 R 536232 CDS YP_002802367.1 226947276 7767921 78843..79346 1 NC_012563.1 hypothetical protein 79346 7767921 CLM_0093 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802367.1 78843 D 536232 CDS YP_002802368.1 226947277 7766839 complement(79351..80511) 1 NC_012563.1 amidohydrolase-like protein 80511 7766839 CLM_0094 Clostridium botulinum A2 str. Kyoto amidohydrolase-like protein YP_002802368.1 79351 R 536232 CDS YP_002802369.1 226947278 7764704 80765..80977 1 NC_012563.1 csfB protein 80977 7764704 CLM_0095 Clostridium botulinum A2 str. Kyoto csfB protein YP_002802369.1 80765 D 536232 CDS YP_002802370.1 226947279 7765787 80956..82404 1 NC_012563.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03711; Orn/Lys/Arg decarboxylase 82404 7765787 CLM_0096 Clostridium botulinum A2 str. Kyoto Orn/Lys/Arg decarboxylase YP_002802370.1 80956 D 536232 CDS YP_002802371.1 226947280 7765375 82428..83123 1 NC_012563.1 putative thymidylate kinase 83123 7765375 CLM_0097 Clostridium botulinum A2 str. Kyoto putative thymidylate kinase YP_002802371.1 82428 D 536232 CDS YP_002802372.1 226947281 7766483 83204..83533 1 NC_012563.1 identified by match to protein family HMM PF06153; hypothetical protein 83533 7766483 CLM_0098 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802372.1 83204 D 536232 CDS YP_002802373.1 226947282 7768032 83551..84495 1 NC_012563.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 84495 7768032 CLM_0099 Clostridium botulinum A2 str. Kyoto DNA polymerase III subunit delta' YP_002802373.1 83551 D 536232 CDS YP_002802374.1 226947283 7764212 84497..85411 1 NC_012563.1 identified by match to protein family HMM PF04468; PSP1 domain-containing protein 85411 7764212 CLM_0100 Clostridium botulinum A2 str. Kyoto PSP1 domain-containing protein YP_002802374.1 84497 D 536232 CDS YP_002802375.1 226947284 7766052 85423..85626 1 NC_012563.1 hypothetical protein 85626 7766052 CLM_0101 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802375.1 85423 D 536232 CDS YP_002802376.1 226947285 7766878 85708..85878 1 NC_012563.1 identified by match to protein family HMM PF00037; ferredoxin 85878 7766878 CLM_0102 Clostridium botulinum A2 str. Kyoto ferredoxin YP_002802376.1 85708 D 536232 CDS YP_002802377.1 226947286 7767586 85999..86739 1 NC_012563.1 hypothetical protein 86739 7767586 CLM_0103 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802377.1 85999 D 536232 CDS YP_002802378.1 226947287 7767719 86759..87613 1 NC_012563.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; tetrapyrrole methylase 87613 7767719 CLM_0104 Clostridium botulinum A2 str. Kyoto tetrapyrrole methylase YP_002802378.1 86759 D 536232 CDS YP_002802379.1 226947288 7767662 87734..88831 1 NC_012563.1 identified by match to protein family HMM PF00877; NlpC/P60 family protein 88831 7767662 CLM_0105 Clostridium botulinum A2 str. Kyoto NlpC/P60 family protein YP_002802379.1 87734 D 536232 CDS YP_002802380.1 226947289 7768049 89984..90595 1 NC_012563.1 identified by match to protein family HMM PF08876; hypothetical protein 90595 7768049 CLM_0108 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802380.1 89984 D 536232 CDS YP_002802381.1 226947290 7765962 91018..92229 1 NC_012563.1 identified by match to protein family HMM PF02274; match to protein family HMM TIGR01078; arginine deiminase 92229 arcA 7765962 arcA Clostridium botulinum A2 str. Kyoto arginine deiminase YP_002802381.1 91018 D 536232 CDS YP_002802382.1 226947291 7768095 complement(92315..92782) 1 NC_012563.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 92782 ispF 7768095 ispF Clostridium botulinum A2 str. Kyoto 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_002802382.1 92315 R 536232 CDS YP_002802383.1 226947292 7766744 complement(92858..93190) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 93190 7766744 CLM_0111 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802383.1 92858 R 536232 CDS YP_002802384.1 226947293 7767091 93518..94387 1 NC_012563.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 94387 7767091 CLM_0112 Clostridium botulinum A2 str. Kyoto polysaccharide deacetylase family protein YP_002802384.1 93518 D 536232 CDS YP_002802385.1 226947294 7765575 complement(94656..94898) 1 NC_012563.1 hypothetical protein 94898 7765575 CLM_0113 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802385.1 94656 R 536232 CDS YP_002802386.1 226947295 7764473 95018..95593 1 NC_012563.1 identified by similarity to SP:P35157; match to protein family HMM PF07670; spore maturation protein A 95593 spmA 7764473 spmA Clostridium botulinum A2 str. Kyoto spore maturation protein A YP_002802386.1 95018 D 536232 CDS YP_002802387.1 226947296 7764489 95606..96124 1 NC_012563.1 identified by similarity to SP:P35158; match to protein family HMM PF07670; spore maturation protein B 96124 spmB 7764489 spmB Clostridium botulinum A2 str. Kyoto spore maturation protein B YP_002802387.1 95606 D 536232 CDS YP_002802388.1 226947297 7767841 complement(96369..97706) 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; MATE efflux family protein 97706 7767841 CLM_0116 Clostridium botulinum A2 str. Kyoto MATE efflux family protein YP_002802388.1 96369 R 536232 CDS YP_002802389.1 226947298 7767489 97850..98422 1 NC_012563.1 identified by match to protein family HMM PF03167; match to protein family HMM TIGR00758; uracil-DNA glycosylase 98422 udgA 7767489 udgA Clostridium botulinum A2 str. Kyoto uracil-DNA glycosylase YP_002802389.1 97850 D 536232 CDS YP_002802390.1 226947299 7766346 98451..98885 1 NC_012563.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 98885 7766346 CLM_0118 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002802390.1 98451 D 536232 CDS YP_002802391.1 226947300 7766079 99267..101204 1 NC_012563.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 101204 metG 7766079 metG Clostridium botulinum A2 str. Kyoto methionyl-tRNA synthetase YP_002802391.1 99267 D 536232 CDS YP_002802392.1 226947301 7764971 101369..102874 1 NC_012563.1 identified by match to protein family HMM PF04286; hypothetical protein 102874 7764971 CLM_0120 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802392.1 101369 D 536232 CDS YP_002802393.1 226947302 7765002 103025..103819 1 NC_012563.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; hydrolase, TatD family 103819 7765002 CLM_0121 Clostridium botulinum A2 str. Kyoto hydrolase, TatD family YP_002802393.1 103025 D 536232 CDS YP_002802394.1 226947303 7767869 104047..105105 1 NC_012563.1 identified by match to protein family HMM PF03990; match to protein family HMM PF06725; match to protein family HMM PF07501; 3D/G5 domain-containing protein 105105 7767869 CLM_0122 Clostridium botulinum A2 str. Kyoto 3D/G5 domain-containing protein YP_002802394.1 104047 D 536232 CDS YP_002802395.1 226947304 7766755 105178..105723 1 NC_012563.1 identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334; primase-like protein 105723 7766755 CLM_0123 Clostridium botulinum A2 str. Kyoto primase-like protein YP_002802395.1 105178 D 536232 CDS YP_002802396.1 226947305 7764656 105725..106552 1 NC_012563.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 106552 ksgA 7764656 ksgA Clostridium botulinum A2 str. Kyoto dimethyladenosine transferase YP_002802396.1 105725 D 536232 CDS YP_002802397.1 226947306 7764412 106631..107926 1 NC_012563.1 hypothetical protein 107926 7764412 CLM_0125 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802397.1 106631 D 536232 CDS YP_002802398.1 226947307 7767447 108085..108672 1 NC_012563.1 hypothetical protein 108672 7767447 CLM_0126 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802398.1 108085 D 536232 CDS YP_002802399.1 226947308 7766504 108840..109673 1 NC_012563.1 putative lipoprotein 109673 7766504 CLM_0127 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002802399.1 108840 D 536232 CDS YP_002802400.1 226947309 7765806 109841..110902 1 NC_012563.1 identified by match to protein family HMM TIGR01730; putative macrolide efflux transporter, RND family, MFP subunit 110902 7765806 CLM_0128 Clostridium botulinum A2 str. Kyoto putative macrolide efflux transporter, RND family, MFP subunit YP_002802400.1 109841 D 536232 CDS YP_002802401.1 226947310 7764323 110913..111608 1 NC_012563.1 identified by match to protein family HMM PF00005; putative macrolide efflux ABC transporter ATP-binding protein 111608 7764323 CLM_0129 Clostridium botulinum A2 str. Kyoto putative macrolide efflux ABC transporter ATP-binding protein YP_002802401.1 110913 D 536232 CDS YP_002802402.1 226947311 7767641 111605..112813 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02687; putative macrolide efflux ABC transporter permease 112813 7767641 CLM_0130 Clostridium botulinum A2 str. Kyoto putative macrolide efflux ABC transporter permease YP_002802402.1 111605 D 536232 CDS YP_002802403.1 226947312 7767977 112895..113737 1 NC_012563.1 MRP protein-like protein 113737 7767977 CLM_0131 Clostridium botulinum A2 str. Kyoto MRP protein-like protein YP_002802403.1 112895 D 536232 CDS YP_002802404.1 226947313 7765393 113877..114068 1 NC_012563.1 iron-sulfur cluster-binding protein 114068 7765393 CLM_0132 Clostridium botulinum A2 str. Kyoto iron-sulfur cluster-binding protein YP_002802404.1 113877 D 536232 CDS YP_002802405.1 226947314 7767737 complement(114514..114690) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 114690 7767737 CLM_0134 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802405.1 114514 R 536232 CDS YP_002802406.1 226947315 7765118 114768..115838 1 NC_012563.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; putative diguanylate cyclase 115838 7765118 CLM_0135 Clostridium botulinum A2 str. Kyoto putative diguanylate cyclase YP_002802406.1 114768 D 536232 CDS YP_002802407.1 226947316 7765258 115895..116623 1 NC_012563.1 identified by match to protein family HMM PF02308; mgtC family protein 116623 7765258 CLM_0136 Clostridium botulinum A2 str. Kyoto mgtC family protein YP_002802407.1 115895 D 536232 CDS YP_002802408.1 226947317 7764637 116913..119054 1 NC_012563.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 119054 nrdD 7764637 nrdD Clostridium botulinum A2 str. Kyoto anaerobic ribonucleoside triphosphate reductase YP_002802408.1 116913 D 536232 CDS YP_002802409.1 226947318 7765486 119071..119586 1 NC_012563.1 identified by match to protein family HMM TIGR02491; anaerobic ribonucleoside-triphosphate reductase activating protein 119586 nrdG 7765486 nrdG Clostridium botulinum A2 str. Kyoto anaerobic ribonucleoside-triphosphate reductase activating protein YP_002802409.1 119071 D 536232 CDS YP_002802410.1 226947319 7764675 complement(120116..120790) 1 NC_012563.1 hypothetical protein 120790 7764675 CLM_0139 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802410.1 120116 R 536232 CDS YP_002802411.1 226947320 7767510 complement(120792..121130) 1 NC_012563.1 identified by match to protein family HMM PF03551; PadR family transcriptional regulator 121130 7767510 CLM_0140 Clostridium botulinum A2 str. Kyoto PadR family transcriptional regulator YP_002802411.1 120792 R 536232 CDS YP_002802412.1 226947321 7766177 complement(121250..121888) 1 NC_012563.1 identified by similarity to PDB:1VJN_A; hypothetical protein 121888 7766177 CLM_0141 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802412.1 121250 R 536232 CDS YP_002802413.1 226947322 7766176 122330..125446 1 NC_012563.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 125446 ileS 7766176 ileS Clostridium botulinum A2 str. Kyoto isoleucyl-tRNA synthetase YP_002802413.1 122330 D 536232 CDS YP_002802414.1 226947323 7765095 125597..126595 1 NC_012563.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcriptional regulator 126595 7765095 CLM_0143 Clostridium botulinum A2 str. Kyoto LacI family transcriptional regulator YP_002802414.1 125597 D 536232 CDS YP_002802415.1 226947324 7768070 126811..130863 1 NC_012563.1 hypothetical protein 130863 7768070 CLM_0144 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802415.1 126811 D 536232 CDS YP_002802416.1 226947325 7766673 130938..132005 1 NC_012563.1 identified by match to protein family HMM PF00483; putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 132005 7766673 CLM_0145 Clostridium botulinum A2 str. Kyoto putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_002802416.1 130938 D 536232 CDS YP_002802417.1 226947326 7767034 132341..133630 1 NC_012563.1 identified by match to protein family HMM PF01969; match to protein family HMM TIGR00299; hypothetical protein 133630 7767034 CLM_0146 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802417.1 132341 D 536232 CDS YP_002802418.1 226947327 7767866 133635..134441 1 NC_012563.1 identified by match to protein family HMM PF01171; match to protein family HMM PF06508; match to protein family HMM TIGR00268; hypothetical protein 134441 7767866 CLM_0147 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802418.1 133635 D 536232 CDS YP_002802419.1 226947328 7766296 134461..135207 1 NC_012563.1 hypothetical protein 135207 7766296 CLM_0148 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802419.1 134461 D 536232 CDS YP_002802420.1 226947329 7767179 135432..136814 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 136814 7767179 CLM_0149 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002802420.1 135432 D 536232 CDS YP_002802421.1 226947330 7766056 137001..138275 1 NC_012563.1 identified by similarity to SP:P94528; match to protein family HMM PF01547; putative arabinose-binding protein 138275 7766056 CLM_0150 Clostridium botulinum A2 str. Kyoto putative arabinose-binding protein YP_002802421.1 137001 D 536232 CDS YP_002802422.1 226947331 7766712 complement(138377..139492) 1 NC_012563.1 identified by similarity to GB:BAA07751.1; match to protein family HMM PF00534; putative mannosyltransferase 139492 7766712 CLM_0151 Clostridium botulinum A2 str. Kyoto putative mannosyltransferase YP_002802422.1 138377 R 536232 CDS YP_002802423.1 226947332 7767849 139658..140668 1 NC_012563.1 identified by match to protein family HMM TIGR02906; CotS family spore coat protein 140668 7767849 CLM_0152 Clostridium botulinum A2 str. Kyoto CotS family spore coat protein YP_002802423.1 139658 D 536232 CDS YP_002802424.1 226947333 7764514 140683..140877 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 140877 7764514 CLM_0153 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802424.1 140683 D 536232 CDS YP_002802425.1 226947334 7765588 140904..141671 1 NC_012563.1 hypothetical protein 141671 7765588 CLM_0154 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802425.1 140904 D 536232 CDS YP_002802426.1 226947335 7766224 141684..142697 1 NC_012563.1 identified by match to protein family HMM TIGR02906; CotS family spore coat protein 142697 7766224 CLM_0155 Clostridium botulinum A2 str. Kyoto CotS family spore coat protein YP_002802426.1 141684 D 536232 CDS YP_002802427.1 226947336 7765189 complement(143051..144178) 1 NC_012563.1 identified by match to protein family HMM PF00534; group 1 glycosyl transferase family 144178 7765189 CLM_0156 Clostridium botulinum A2 str. Kyoto group 1 glycosyl transferase family YP_002802427.1 143051 R 536232 CDS YP_002802428.1 226947337 7766588 144295..145299 1 NC_012563.1 identified by similarity to SP:P46914; match to protein family HMM TIGR02906; spore coat protein CotS 145299 cotS 7766588 cotS Clostridium botulinum A2 str. Kyoto spore coat protein CotS YP_002802428.1 144295 D 536232 CDS YP_002802429.1 226947338 7765500 145423..146325 1 NC_012563.1 identified by match to protein family HMM PF05582; match to protein family HMM TIGR02855; sporulation peptidase YabG 146325 7765500 CLM_0158 Clostridium botulinum A2 str. Kyoto sporulation peptidase YabG YP_002802429.1 145423 D 536232 CDS YP_002802430.1 226947339 7764648 146521..146757 1 NC_012563.1 identified by match to protein family HMM PF06257; hypothetical protein 146757 7764648 CLM_0159 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802430.1 146521 D 536232 CDS YP_002802431.1 226947340 7767294 146861..148423 1 NC_012563.1 identified by match to protein family HMM PF01476; LysM domain-containing protein 148423 7767294 CLM_0160 Clostridium botulinum A2 str. Kyoto LysM domain-containing protein YP_002802431.1 146861 D 536232 CDS YP_002802432.1 226947341 7766358 148669..148782 1 NC_012563.1 hypothetical protein 148782 7766358 CLM_0161 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802432.1 148669 D 536232 CDS YP_002802433.1 226947342 7766717 148752..149552 1 NC_012563.1 identified by match to protein family HMM PF03575; match to protein family HMM TIGR02069; cyanophycinase 149552 cphB 7766717 cphB Clostridium botulinum A2 str. Kyoto cyanophycinase YP_002802433.1 148752 D 536232 CDS YP_002802434.1 226947343 7766142 149596..152217 1 NC_012563.1 catalyze the formation of cyanophycin which may act to store excess nitrogen; cyanophycin synthetase 152217 cphA 7766142 cphA Clostridium botulinum A2 str. Kyoto cyanophycin synthetase YP_002802434.1 149596 D 536232 CDS YP_002802435.1 226947344 7764464 152310..153152 1 NC_012563.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 153152 ipk 7764464 ipk Clostridium botulinum A2 str. Kyoto 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002802435.1 152310 D 536232 CDS YP_002802436.1 226947345 7767877 153320..153517 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 153517 7767877 CLM_0165 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802436.1 153320 D 536232 CDS YP_002802437.1 226947346 7764630 153578..155098 1 NC_012563.1 identified by match to protein family HMM PF03323; spore germination protein 155098 7764630 CLM_0166 Clostridium botulinum A2 str. Kyoto spore germination protein YP_002802437.1 153578 D 536232 CDS YP_002802438.1 226947347 7767787 155118..156215 1 NC_012563.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912; spore germination protein 156215 7767787 CLM_0167 Clostridium botulinum A2 str. Kyoto spore germination protein YP_002802438.1 155118 D 536232 CDS YP_002802439.1 226947348 7768064 156265..157446 1 NC_012563.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887; germination protein, Ger(x)C family 157446 7768064 CLM_0168 Clostridium botulinum A2 str. Kyoto germination protein, Ger(x)C family YP_002802439.1 156265 D 536232 CDS YP_002802440.1 226947349 7766575 157520..158152 1 NC_012563.1 identified by match to protein family HMM PF09551; match to protein family HMM TIGR02837; stage II sporulation protein R 158152 spoIIR 7766575 spoIIR Clostridium botulinum A2 str. Kyoto stage II sporulation protein R YP_002802440.1 157520 D 536232 CDS YP_002802441.1 226947350 7765215 complement(158189..159430) 1 NC_012563.1 identified by match to protein family HMM PF04101; match to protein family HMM PF06925; hypothetical protein 159430 7765215 CLM_0170 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802441.1 158189 R 536232 CDS YP_002802442.1 226947351 7765754 159803..161173 1 NC_012563.1 identified by match to protein family HMM PF03413; match to protein family HMM TIGR02889; germination protein YpeB 161173 ypeB 7765754 ypeB Clostridium botulinum A2 str. Kyoto germination protein YpeB YP_002802442.1 159803 D 536232 CDS YP_002802443.1 226947352 7764887 161276..162256 1 NC_012563.1 identified by match to protein family HMM PF02568; hypothetical protein 162256 7764887 CLM_0172 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802443.1 161276 D 536232 CDS YP_002802444.1 226947353 7767979 162281..162709 1 NC_012563.1 identified by match to protein family HMM PF09148; hypothetical protein 162709 7767979 CLM_0173 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802444.1 162281 D 536232 CDS YP_002802445.1 226947354 7767075 162841..163140 1 NC_012563.1 hypothetical protein 163140 7767075 CLM_0174 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802445.1 162841 D 536232 CDS YP_002802446.1 226947355 7765280 163374..164975 1 NC_012563.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 164975 pyrG 7765280 pyrG Clostridium botulinum A2 str. Kyoto CTP synthetase YP_002802446.1 163374 D 536232 CDS YP_002802447.1 226947356 7764435 165423..165767 1 NC_012563.1 hypothetical protein 165767 7764435 CLM_0176 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802447.1 165423 D 536232 CDS YP_002802448.1 226947357 7765920 165939..167384 1 NC_012563.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 167384 rho 7765920 rho Clostridium botulinum A2 str. Kyoto transcription termination factor Rho YP_002802448.1 165939 D 536232 CDS YP_002802449.1 226947358 7767258 complement(167424..167642) 1 NC_012563.1 identified by match to protein family HMM PF01197; match to protein family HMM TIGR00105; 50S ribosomal protein L31 167642 rpmE 7767258 rpmE Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L31 YP_002802449.1 167424 R 536232 CDS YP_002802450.1 226947359 7765410 167869..168444 1 NC_012563.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 168444 tdk 7765410 tdk Clostridium botulinum A2 str. Kyoto thymidine kinase YP_002802450.1 167869 D 536232 CDS YP_002802451.1 226947360 7766251 168461..169378 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF07136; hypothetical protein 169378 7766251 CLM_0180 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802451.1 168461 D 536232 CDS YP_002802452.1 226947361 7767711 169386..170237 1 NC_012563.1 identified by match to protein family HMM PF05175; match to protein family HMM TIGR00536; match to protein family HMM TIGR03534; protein-(glutamine-N5) methyltransferase, release factor-specific 170237 prmC 7767711 prmC Clostridium botulinum A2 str. Kyoto protein-(glutamine-N5) methyltransferase, release factor-specific YP_002802452.1 169386 D 536232 CDS YP_002802453.1 226947362 7764510 170319..171395 1 NC_012563.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 171395 prfA 7764510 prfA Clostridium botulinum A2 str. Kyoto peptide chain release factor 1 YP_002802453.1 170319 D 536232 CDS YP_002802454.1 226947363 7766841 171423..172031 1 NC_012563.1 hypothetical protein 172031 7766841 CLM_0183 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802454.1 171423 D 536232 CDS YP_002802455.1 226947364 7767775 172090..172809 1 NC_012563.1 identified by match to protein family HMM PF02535; ZIP transporter family protein 172809 7767775 CLM_0184 Clostridium botulinum A2 str. Kyoto ZIP transporter family protein YP_002802455.1 172090 D 536232 CDS YP_002802456.1 226947365 7765106 172830..173885 1 NC_012563.1 identified by match to protein family HMM PF01300; match to protein family HMM PF03481; match to protein family HMM TIGR00057; Sua5/YciO/YrdC/YwlC family protein 173885 7765106 CLM_0185 Clostridium botulinum A2 str. Kyoto Sua5/YciO/YrdC/YwlC family protein YP_002802456.1 172830 D 536232 CDS YP_002802457.1 226947366 7766027 173895..174347 1 NC_012563.1 identified by match to protein family HMM PF01451; low molecular weight protein tyrosine phosphatase 174347 7766027 CLM_0186 Clostridium botulinum A2 str. Kyoto low molecular weight protein tyrosine phosphatase YP_002802457.1 173895 D 536232 CDS YP_002802458.1 226947367 7766874 174407..174844 1 NC_012563.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 174844 rpiB 7766874 rpiB Clostridium botulinum A2 str. Kyoto ribose-5-phosphate isomerase B YP_002802458.1 174407 D 536232 CDS YP_002802459.1 226947368 7765016 174874..175503 1 NC_012563.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 175503 upp 7765016 upp Clostridium botulinum A2 str. Kyoto uracil phosphoribosyltransferase YP_002802459.1 174874 D 536232 CDS YP_002802460.1 226947369 7766113 complement(175731..175907) 1 NC_012563.1 hypothetical protein 175907 7766113 CLM_0189 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802460.1 175731 R 536232 CDS YP_002802461.1 226947370 7766732 176642..177130 1 NC_012563.1 identified by match to protein family HMM PF00383; cytidine/deoxycytidylate deaminase family protein 177130 7766732 CLM_0190 Clostridium botulinum A2 str. Kyoto cytidine/deoxycytidylate deaminase family protein YP_002802461.1 176642 D 536232 CDS YP_002802462.1 226947371 7767903 177238..178272 1 NC_012563.1 identified by similarity to SP:O34753; match to protein family HMM PF00953; UDP-phosphate N-acetylgalactosaminyl-1-phosphate transferase 178272 tagO 7767903 tagO Clostridium botulinum A2 str. Kyoto UDP-phosphate N-acetylgalactosaminyl-1-phosphate transferase YP_002802462.1 177238 D 536232 CDS YP_002802463.1 226947372 7765507 178286..179443 1 NC_012563.1 identified by similarity to SP:P39131; match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase 179443 mnaA 7765507 mnaA Clostridium botulinum A2 str. Kyoto UDP-N-acetylglucosamine 2-epimerase YP_002802463.1 178286 D 536232 CDS YP_002802464.1 226947373 7766597 179935..180303 1 NC_012563.1 identified by similarity to GB:AAK72436.1; ATP synthase F0, I subunit 180303 atpI 7766597 atpI Clostridium botulinum A2 str. Kyoto ATP synthase F0, I subunit YP_002802464.1 179935 D 536232 CDS YP_002802465.1 226947374 7767355 180318..180998 1 NC_012563.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 180998 atpB 7767355 atpB Clostridium botulinum A2 str. Kyoto F0F1 ATP synthase subunit A YP_002802465.1 180318 D 536232 CDS YP_002802466.1 226947375 7764353 181039..181278 1 NC_012563.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 181278 atpE 7764353 atpE Clostridium botulinum A2 str. Kyoto F0F1 ATP synthase subunit C YP_002802466.1 181039 D 536232 CDS YP_002802467.1 226947376 7766117 181354..181833 1 NC_012563.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel; F0F1 ATP synthase subunit B 181833 atpF 7766117 atpF Clostridium botulinum A2 str. Kyoto F0F1 ATP synthase subunit B YP_002802467.1 181354 D 536232 CDS YP_002802468.1 226947377 7766229 181836..182375 1 NC_012563.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 182375 atpH 7766229 atpH Clostridium botulinum A2 str. Kyoto F0F1 ATP synthase subunit delta YP_002802468.1 181836 D 536232 CDS YP_002802469.1 226947378 7767480 182386..183900 1 NC_012563.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 183900 atpA 7767480 atpA Clostridium botulinum A2 str. Kyoto F0F1 ATP synthase subunit alpha YP_002802469.1 182386 D 536232 CDS YP_002802470.1 226947379 7766207 183922..184770 1 NC_012563.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 184770 atpG 7766207 atpG Clostridium botulinum A2 str. Kyoto F0F1 ATP synthase subunit gamma YP_002802470.1 183922 D 536232 CDS YP_002802471.1 226947380 7767049 184784..186175 1 NC_012563.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 186175 atpD 7767049 atpD Clostridium botulinum A2 str. Kyoto F0F1 ATP synthase subunit beta YP_002802471.1 184784 D 536232 CDS YP_002802472.1 226947381 7765917 186200..186601 1 NC_012563.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon 186601 atpC 7765917 atpC Clostridium botulinum A2 str. Kyoto F0F1 ATP synthase subunit epsilon YP_002802472.1 186200 D 536232 CDS YP_002802473.1 226947382 7764738 186794..187501 1 NC_012563.1 hypothetical protein 187501 7764738 CLM_0202 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802473.1 186794 D 536232 CDS YP_002802474.1 226947383 7767563 187525..188781 1 NC_012563.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 188781 murA 7767563 murA Clostridium botulinum A2 str. Kyoto UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002802474.1 187525 D 536232 CDS YP_002802475.1 226947384 7766492 189049..190125 1 NC_012563.1 identified by match to protein family HMM PF08486; match to protein family HMM TIGR02669; match to protein family HMM TIGR02870; stage II sporulation protein D 190125 spoIID 7766492 spoIID Clostridium botulinum A2 str. Kyoto stage II sporulation protein D YP_002802475.1 189049 D 536232 CDS YP_002802476.1 226947385 7765407 190599..191345 1 NC_012563.1 identified by match to protein family HMM PF01551; putative peptidase 191345 7765407 CLM_0205 Clostridium botulinum A2 str. Kyoto putative peptidase YP_002802476.1 190599 D 536232 CDS YP_002802477.1 226947386 7764241 191453..191707 1 NC_012563.1 identified by similarity to SP:P15281; match to protein family HMM TIGR02844; stage III sporulation protein D 191707 spoIIID 7764241 spoIIID Clostridium botulinum A2 str. Kyoto stage III sporulation protein D YP_002802477.1 191453 D 536232 CDS YP_002802478.1 226947387 7766736 191807..192835 1 NC_012563.1 identified by similarity to SP:P39751; match to protein family HMM PF02491; match to protein family HMM PF06723; match to protein family HMM TIGR00904; rod shape-determining protein Mbl 192835 mbl 7766736 mbl Clostridium botulinum A2 str. Kyoto rod shape-determining protein Mbl YP_002802478.1 191807 D 536232 CDS YP_002802479.1 226947388 7764576 complement(192961..193485) 1 NC_012563.1 identified by match to protein family HMM PF06866; match to protein family HMM TIGR02841; putative sporulation protein YyaC 193485 7764576 CLM_0208 Clostridium botulinum A2 str. Kyoto putative sporulation protein YyaC YP_002802479.1 192961 R 536232 CDS YP_002802480.1 226947389 7767201 complement(193534..194256) 1 NC_012563.1 identified by match to protein family HMM PF01171; hypothetical protein 194256 7767201 CLM_0209 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802480.1 193534 R 536232 CDS YP_002802481.1 226947390 7768204 195232..196407 1 NC_012563.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 196407 metK 7768204 metK Clostridium botulinum A2 str. Kyoto S-adenosylmethionine synthetase YP_002802481.1 195232 D 536232 CDS YP_002802482.1 226947391 7765418 196598..198832 1 NC_012563.1 identified by match to protein family HMM TIGR01448; helicase, RecD/TraA family 198832 7765418 CLM_0217 Clostridium botulinum A2 str. Kyoto helicase, RecD/TraA family YP_002802482.1 196598 D 536232 CDS YP_002802483.1 226947392 7764563 198858..199880 1 NC_012563.1 hypothetical protein 199880 7764563 CLM_0218 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802483.1 198858 D 536232 CDS YP_002802484.1 226947393 7766776 199853..200530 1 NC_012563.1 identified by match to protein family HMM PF00156; comF protein 200530 7766776 CLM_0219 Clostridium botulinum A2 str. Kyoto comF protein YP_002802484.1 199853 D 536232 CDS YP_002802485.1 226947394 7766063 200955..201482 1 NC_012563.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741; ribosomal subunit interface protein 201482 yfiA 7766063 yfiA Clostridium botulinum A2 str. Kyoto ribosomal subunit interface protein YP_002802485.1 200955 D 536232 CDS YP_002802486.1 226947395 7764966 201710..204217 1 NC_012563.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 204217 secA 7764966 secA Clostridium botulinum A2 str. Kyoto preprotein translocase subunit SecA YP_002802486.1 201710 D 536232 CDS YP_002802487.1 226947396 7767320 204581..205558 1 NC_012563.1 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA; peptide chain release factor 2 205558 prfB 7767320 prfB Clostridium botulinum A2 str. Kyoto peptide chain release factor 2 YP_002802487.1 204581 D 536232 CDS YP_002802488.1 226947397 7766166 complement(205861..207225) 1 NC_012563.1 identified by match to protein family HMM PF04389; peptidase family protein 207225 7766166 CLM_0223 Clostridium botulinum A2 str. Kyoto peptidase family protein YP_002802488.1 205861 R 536232 CDS YP_002802489.1 226947398 7766153 207333..209489 1 NC_012563.1 identified by match to protein family HMM PF00575; match to protein family HMM PF09371; RNA-binding protein 209489 7766153 CLM_0224 Clostridium botulinum A2 str. Kyoto RNA-binding protein YP_002802489.1 207333 D 536232 CDS YP_002802490.1 226947399 7765244 209773..210366 1 NC_012563.1 hypothetical protein 210366 7765244 CLM_0226 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802490.1 209773 D 536232 CDS YP_002802491.1 226947400 7766290 210777..212426 1 NC_012563.1 hypothetical protein 212426 7766290 CLM_0227 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802491.1 210777 D 536232 CDS YP_002802492.1 226947401 7766961 212447..212707 1 NC_012563.1 hypothetical protein 212707 7766961 CLM_0228 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802492.1 212447 D 536232 CDS YP_002802493.1 226947402 7768040 212721..213407 1 NC_012563.1 identified by match to protein family HMM PF00149; Ser/Thr protein phosphatase family protein 213407 7768040 CLM_0229 Clostridium botulinum A2 str. Kyoto Ser/Thr protein phosphatase family protein YP_002802493.1 212721 D 536232 CDS YP_002802494.1 226947403 7765832 213491..213772 1 NC_012563.1 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 213772 7765832 CLM_0230 Clostridium botulinum A2 str. Kyoto ArsR family transcriptional regulator YP_002802494.1 213491 D 536232 CDS YP_002802495.1 226947404 7766653 213812..216265 1 NC_012563.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00581; match to protein family HMM PF01206; match to protein family HMM PF02852; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase family protein 216265 7766653 CLM_0231 Clostridium botulinum A2 str. Kyoto pyridine nucleotide-disulfide oxidoreductase family protein YP_002802495.1 213812 D 536232 CDS YP_002802496.1 226947405 7767944 complement(216293..217147) 1 NC_012563.1 hypothetical protein 217147 7767944 CLM_0232 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802496.1 216293 R 536232 CDS YP_002802497.1 226947406 7764838 217304..218092 1 NC_012563.1 identified by match to protein family HMM PF04607; RelA/SpoT domain-containing protein 218092 7764838 CLM_0233 Clostridium botulinum A2 str. Kyoto RelA/SpoT domain-containing protein YP_002802497.1 217304 D 536232 CDS YP_002802498.1 226947407 7766362 complement(218397..220838) 1 NC_012563.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 220838 leuS 7766362 leuS Clostridium botulinum A2 str. Kyoto leucyl-tRNA synthetase YP_002802498.1 218397 R 536232 CDS YP_002802499.1 226947408 7767770 complement(221215..221565) 1 NC_012563.1 identified by match to protein family HMM PF00581; hypothetical protein 221565 7767770 CLM_0235 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802499.1 221215 R 536232 CDS YP_002802500.1 226947409 7768169 complement(221933..222457) 1 NC_012563.1 hypothetical protein 222457 7768169 CLM_0237 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802500.1 221933 R 536232 CDS YP_002802501.1 226947410 7766404 complement(222482..223081) 1 NC_012563.1 identified by match to protein family HMM PF00226; match to protein family HMM PF07719; molecular chaperone, DnaJ family 223081 7766404 CLM_0238 Clostridium botulinum A2 str. Kyoto molecular chaperone, DnaJ family YP_002802501.1 222482 R 536232 CDS YP_002802502.1 226947411 7765477 complement(223068..223943) 1 NC_012563.1 hypothetical protein 223943 7765477 CLM_0239 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802502.1 223068 R 536232 CDS YP_002802503.1 226947412 7764611 complement(223947..224486) 1 NC_012563.1 identified by match to protein family HMM PF01928; putative adenylyl cyclase CyaB 224486 7764611 CLM_0240 Clostridium botulinum A2 str. Kyoto putative adenylyl cyclase CyaB YP_002802503.1 223947 R 536232 CDS YP_002802504.1 226947413 7764596 224793..225830 1 NC_012563.1 hypothetical protein 225830 7764596 CLM_0241 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802504.1 224793 D 536232 CDS YP_002802505.1 226947414 7766709 complement(226102..227028) 1 NC_012563.1 identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859; fructose-1,6-bisphosphate aldolase, class II 227028 fba 7766709 fba Clostridium botulinum A2 str. Kyoto fructose-1,6-bisphosphate aldolase, class II YP_002802505.1 226102 R 536232 CDS YP_002802506.1 226947415 7765900 complement(227242..227526) 1 NC_012563.1 hypothetical protein 227526 7765900 CLM_0243 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802506.1 227242 R 536232 CDS YP_002802507.1 226947416 7764915 complement(227643..228311) 1 NC_012563.1 identified by match to protein family HMM PF04239; hypothetical protein 228311 7764915 CLM_0244 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802507.1 227643 R 536232 CDS YP_002802508.1 226947417 7765147 228436..230094 1 NC_012563.1 identified by similarity to SP:O32033; match to protein family HMM PF00485; putative threonyl-tRNA synthetase/uridine kinase 230094 7765147 CLM_0245 Clostridium botulinum A2 str. Kyoto putative threonyl-tRNA synthetase/uridine kinase YP_002802508.1 228436 D 536232 CDS YP_002802509.1 226947418 7765793 230232..230363 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 230363 7765793 CLM_0246 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802509.1 230232 D 536232 CDS YP_002802510.1 226947419 7766408 complement(230464..230985) 1 NC_012563.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473; CDP-diacylglycerol--serine O-phosphatidyltransferase 230985 pssA 7766408 pssA Clostridium botulinum A2 str. Kyoto CDP-diacylglycerol--serine O-phosphatidyltransferase YP_002802510.1 230464 R 536232 CDS YP_002802511.1 226947420 7766783 231172..231588 1 NC_012563.1 identified by match to protein family HMM PF00571; CBS domain-containing protein 231588 7766783 CLM_0248 Clostridium botulinum A2 str. Kyoto CBS domain-containing protein YP_002802511.1 231172 D 536232 CDS YP_002802512.1 226947421 7767888 231694..232578 1 NC_012563.1 similar to YegS from E. coli; putative lipid kinase 232578 7767888 CLM_0249 Clostridium botulinum A2 str. Kyoto putative lipid kinase YP_002802512.1 231694 D 536232 CDS YP_002802513.1 226947422 7765028 232652..233296 1 NC_012563.1 hypothetical protein 233296 7765028 CLM_0250 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802513.1 232652 D 536232 CDS YP_002802514.1 226947423 7767027 complement(233620..235557) 1 NC_012563.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08497; hypothetical protein 235557 7767027 CLM_0251 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802514.1 233620 R 536232 CDS YP_002802515.1 226947424 7768091 236152..237417 1 NC_012563.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03448; match to protein family HMM PF05239; PRC-barrel domain/MgtE domain/CBS domain-containing protein 237417 7768091 CLM_0253 Clostridium botulinum A2 str. Kyoto PRC-barrel domain/MgtE domain/CBS domain-containing protein YP_002802515.1 236152 D 536232 CDS YP_002802516.1 226947425 7764367 237646..238341 1 NC_012563.1 identified by match to protein family HMM PF01471; match to protein family HMM PF07486; match to protein family HMM TIGR02869; spore-cortex-lytic enzyme 238341 sleB 7764367 sleB Clostridium botulinum A2 str. Kyoto spore-cortex-lytic enzyme YP_002802516.1 237646 D 536232 CDS YP_002802517.1 226947426 7765466 238705..239619 1 NC_012563.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; cysteine synthase A 239619 cysK 7765466 cysK Clostridium botulinum A2 str. Kyoto cysteine synthase A YP_002802517.1 238705 D 536232 CDS YP_002802518.1 226947427 7765479 239634..240230 1 NC_012563.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172; serine O-acetyltransferase 240230 cysE 7765479 cysE Clostridium botulinum A2 str. Kyoto serine O-acetyltransferase YP_002802518.1 239634 D 536232 CDS YP_002802519.1 226947428 7764729 240252..241217 1 NC_012563.1 identified by match to protein family HMM PF08331; iron-sulfur cluster-binding protein 241217 7764729 CLM_0257 Clostridium botulinum A2 str. Kyoto iron-sulfur cluster-binding protein YP_002802519.1 240252 D 536232 CDS YP_002802520.1 226947429 7765200 241365..242066 1 NC_012563.1 identified by similarity to GB:AAC46006.1; match to protein family HMM PF01553; glycerol-3-phosphate O-acyltransferase 242066 plsD 7765200 plsD Clostridium botulinum A2 str. Kyoto glycerol-3-phosphate O-acyltransferase YP_002802520.1 241365 D 536232 CDS YP_002802521.1 226947430 7764409 242159..242800 1 NC_012563.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III 242800 nth 7764409 nth Clostridium botulinum A2 str. Kyoto endonuclease III YP_002802521.1 242159 D 536232 CDS YP_002802522.1 226947431 7767962 243075..244247 1 NC_012563.1 identified by match to protein family HMM PF00390; match to protein family HMM PF03949; malate dehydrogenase (oxaloacetate-decarboxylating) 244247 7767962 CLM_0260 Clostridium botulinum A2 str. Kyoto malate dehydrogenase (oxaloacetate-decarboxylating) YP_002802522.1 243075 D 536232 CDS YP_002802523.1 226947432 7767123 complement(244274..245503) 1 NC_012563.1 identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00177; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; competence damage-inducible protein A 245503 7767123 CLM_0261 Clostridium botulinum A2 str. Kyoto competence damage-inducible protein A YP_002802523.1 244274 R 536232 CDS YP_002802524.1 226947433 7765156 complement(245529..246512) 1 NC_012563.1 hypothetical protein 246512 7765156 CLM_0262 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802524.1 245529 R 536232 CDS YP_002802525.1 226947434 7767744 complement(246622..247656) 1 NC_012563.1 identified by match to protein family HMM PF05343; glutamyl aminopeptidase family protein 247656 7767744 CLM_0263 Clostridium botulinum A2 str. Kyoto glutamyl aminopeptidase family protein YP_002802525.1 246622 R 536232 CDS YP_002802526.1 226947435 7767453 247784..248944 1 NC_012563.1 identified by match to protein family HMM PF04294; vanW-like family protein 248944 7767453 CLM_0264 Clostridium botulinum A2 str. Kyoto vanW-like family protein YP_002802526.1 247784 D 536232 CDS YP_002802527.1 226947436 7766568 249149..250501 1 NC_012563.1 identified by match to protein family HMM PF04294; match to protein family HMM PF07501; vanW-like family protein 250501 7766568 CLM_0265 Clostridium botulinum A2 str. Kyoto vanW-like family protein YP_002802527.1 249149 D 536232 CDS YP_002802528.1 226947437 7765981 250648..251655 1 NC_012563.1 identified by similarity to SP:P37956; match to protein family HMM PF04055; spore photoproduct lyase 251655 splB 7765981 splB Clostridium botulinum A2 str. Kyoto spore photoproduct lyase YP_002802528.1 250648 D 536232 CDS YP_002802529.1 226947438 7764493 251783..252250 1 NC_012563.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00185; hypothetical protein 252250 7764493 CLM_0267 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802529.1 251783 D 536232 CDS YP_002802530.1 226947439 7765270 252263..253102 1 NC_012563.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; DegV family protein 253102 7765270 CLM_0268 Clostridium botulinum A2 str. Kyoto DegV family protein YP_002802530.1 252263 D 536232 CDS YP_002802531.1 226947440 7764361 253396..254499 1 NC_012563.1 identified by match to protein family HMM PF02608; bmp family lipoprotein 254499 7764361 CLM_0269 Clostridium botulinum A2 str. Kyoto bmp family lipoprotein YP_002802531.1 253396 D 536232 CDS YP_002802532.1 226947441 7767529 254665..256215 1 NC_012563.1 identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein 256215 7767529 CLM_0270 Clostridium botulinum A2 str. Kyoto sugar ABC transporter ATP-binding protein YP_002802532.1 254665 D 536232 CDS YP_002802533.1 226947442 7766654 256217..257320 1 NC_012563.1 identified by match to protein family HMM PF02653; sugar ABC transporter permease 257320 7766654 CLM_0271 Clostridium botulinum A2 str. Kyoto sugar ABC transporter permease YP_002802533.1 256217 D 536232 CDS YP_002802534.1 226947443 7765705 257313..258239 1 NC_012563.1 identified by match to protein family HMM PF02653; sugar ABC transporter permease 258239 7765705 CLM_0272 Clostridium botulinum A2 str. Kyoto sugar ABC transporter permease YP_002802534.1 257313 D 536232 CDS YP_002802535.1 226947444 7767528 258351..259076 1 NC_012563.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 259076 7767528 CLM_0273 Clostridium botulinum A2 str. Kyoto polysaccharide deacetylase family protein YP_002802535.1 258351 D 536232 CDS YP_002802536.1 226947445 7767947 259405..260778 1 NC_012563.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 260778 rpoN 7767947 rpoN Clostridium botulinum A2 str. Kyoto RNA polymerase factor sigma-54 YP_002802536.1 259405 D 536232 CDS YP_002802537.1 226947446 7767067 261066..262097 1 NC_012563.1 identified by similarity to SP:O32253; match to protein family HMM PF04198; central glycolytic genes regulator 262097 cggR 7767067 cggR Clostridium botulinum A2 str. Kyoto central glycolytic genes regulator YP_002802537.1 261066 D 536232 CDS YP_002802538.1 226947447 7766950 262175..263182 1 NC_012563.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase 263182 gap 7766950 gap Clostridium botulinum A2 str. Kyoto glyceraldehyde-3-phosphate dehydrogenase YP_002802538.1 262175 D 536232 CDS YP_002802539.1 226947448 7766208 263479..264675 1 NC_012563.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 264675 pgk 7766208 pgk Clostridium botulinum A2 str. Kyoto phosphoglycerate kinase YP_002802539.1 263479 D 536232 CDS YP_002802540.1 226947449 7765999 264737..265483 1 NC_012563.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 265483 tpiA 7765999 tpiA Clostridium botulinum A2 str. Kyoto triosephosphate isomerase YP_002802540.1 264737 D 536232 CDS YP_002802541.1 226947450 7765751 265575..267104 1 NC_012563.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 267104 gpmI 7765751 gpmI Clostridium botulinum A2 str. Kyoto phosphoglyceromutase YP_002802541.1 265575 D 536232 CDS YP_002802542.1 226947451 7765610 267160..268455 1 NC_012563.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 268455 eno 7765610 eno Clostridium botulinum A2 str. Kyoto phosphopyruvate hydratase YP_002802542.1 267160 D 536232 CDS YP_002802543.1 226947452 7764858 268678..268911 1 NC_012563.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG 268911 secG 7764858 secG Clostridium botulinum A2 str. Kyoto preprotein translocase subunit SecG YP_002802543.1 268678 D 536232 CDS YP_002802544.1 226947453 7768010 269120..271297 1 NC_012563.1 identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063; ribonuclease R 271297 rnr 7768010 rnr Clostridium botulinum A2 str. Kyoto ribonuclease R YP_002802544.1 269120 D 536232 CDS YP_002802545.1 226947454 7765307 271706..272464 1 NC_012563.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 272464 surE 7765307 surE Clostridium botulinum A2 str. Kyoto stationary phase survival protein SurE YP_002802545.1 271706 D 536232 CDS YP_002802546.1 226947455 7764418 272721..273191 1 NC_012563.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 273191 smpB 7764418 smpB Clostridium botulinum A2 str. Kyoto SsrA-binding protein YP_002802546.1 272721 D 536232 CDS YP_002802547.1 226947456 7767964 complement(273330..274493) 1 NC_012563.1 identified by match to protein family HMM PF00375; sodium:dicarboxylate symporter family protein 274493 7767964 CLM_0285 Clostridium botulinum A2 str. Kyoto sodium:dicarboxylate symporter family protein YP_002802547.1 273330 R 536232 CDS YP_002802548.1 226947457 7767096 complement(275936..276346) 1 NC_012563.1 hypothetical protein 276346 7767096 CLM_0286 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802548.1 275936 R 536232 CDS YP_002802549.1 226947458 7765473 276640..277971 1 NC_012563.1 identified by match to protein family HMM PF01565; match to protein family HMM PF08031; FAD-binding protein 277971 7765473 CLM_0287 Clostridium botulinum A2 str. Kyoto FAD-binding protein YP_002802549.1 276640 D 536232 CDS YP_002802550.1 226947459 7764372 278468..279244 1 NC_012563.1 identified by match to protein family HMM PF03848; match to protein family HMM PF08241; match to protein family HMM PF08242; SAM-dependent methyltransferase 279244 7764372 CLM_0288 Clostridium botulinum A2 str. Kyoto SAM-dependent methyltransferase YP_002802550.1 278468 D 536232 CDS YP_002802551.1 226947460 7767185 279296..279991 1 NC_012563.1 identified by match to protein family HMM PF00027; cyclic nucleotide-binding protein 279991 7767185 CLM_0289 Clostridium botulinum A2 str. Kyoto cyclic nucleotide-binding protein YP_002802551.1 279296 D 536232 CDS YP_002802552.1 226947461 7766291 280143..280352 1 NC_012563.1 FAD/FMN-binding family oxidoreductase 280352 7766291 CLM_0290 Clostridium botulinum A2 str. Kyoto FAD/FMN-binding family oxidoreductase YP_002802552.1 280143 D 536232 CDS YP_002802553.1 226947462 7765444 280537..281961 1 NC_012563.1 identified by similarity to GB:CAB71551.1; match to protein family HMM PF00282; putative pyridoxal-dependent decarboxylase 281961 7765444 CLM_0291 Clostridium botulinum A2 str. Kyoto putative pyridoxal-dependent decarboxylase YP_002802553.1 280537 D 536232 CDS YP_002802554.1 226947463 7764854 283359..284975 1 NC_012563.1 identified by similarity to SP:P81701; match to protein family HMM PF01569; PAP2 family protein 284975 7764854 CLM_0294 Clostridium botulinum A2 str. Kyoto PAP2 family protein YP_002802554.1 283359 D 536232 CDS YP_002802555.1 226947464 7767233 285196..285897 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; regulatory protein VanR 285897 7767233 CLM_0295 Clostridium botulinum A2 str. Kyoto regulatory protein VanR YP_002802555.1 285196 D 536232 CDS YP_002802556.1 226947465 7766403 286025..286945 1 NC_012563.1 identified by match to protein family HMM PF00005; bacitracin transport ATP-binding protein BcrA 286945 7766403 CLM_0296 Clostridium botulinum A2 str. Kyoto bacitracin transport ATP-binding protein BcrA YP_002802556.1 286025 D 536232 CDS YP_002802557.1 226947466 7766044 286938..287690 1 NC_012563.1 hypothetical protein 287690 7766044 CLM_0297 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802557.1 286938 D 536232 CDS YP_002802558.1 226947467 7766940 287778..288686 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 288686 7766940 CLM_0298 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002802558.1 287778 D 536232 CDS YP_002802559.1 226947468 7765173 288864..289520 1 NC_012563.1 identified by match to protein family HMM PF07883; hypothetical protein 289520 7765173 CLM_0299 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802559.1 288864 D 536232 CDS YP_002802560.1 226947469 7765795 289863..290978 1 NC_012563.1 hypothetical protein 290978 7765795 CLM_0300 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802560.1 289863 D 536232 CDS YP_002802561.1 226947470 7766715 291523..292986 1 NC_012563.1 identified by similarity to SP:P25737; match to protein family HMM PF00324; putative lysine-specific permease 292986 7766715 CLM_0302 Clostridium botulinum A2 str. Kyoto putative lysine-specific permease YP_002802561.1 291523 D 536232 CDS YP_002802562.1 226947471 7767551 293530..294264 1 NC_012563.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 294264 7767551 CLM_0303 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002802562.1 293530 D 536232 CDS YP_002802563.1 226947472 7767235 294378..294890 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 294890 7767235 CLM_0304 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002802563.1 294378 D 536232 CDS YP_002802564.1 226947473 7764431 294916..295200 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; cytidine/deoxycytidylate deaminase family protein 295200 7764431 CLM_0305 Clostridium botulinum A2 str. Kyoto cytidine/deoxycytidylate deaminase family protein YP_002802564.1 294916 D 536232 CDS YP_002802565.1 226947474 7764943 295463..296365 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 296365 7764943 CLM_0306 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002802565.1 295463 D 536232 CDS YP_002802566.1 226947475 7766151 296391..296915 1 NC_012563.1 identified by match to protein family HMM PF01872; RibD domain-containing protein 296915 7766151 CLM_0307 Clostridium botulinum A2 str. Kyoto RibD domain-containing protein YP_002802566.1 296391 D 536232 CDS YP_002802567.1 226947476 7767943 296978..297907 1 NC_012563.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 297907 7767943 CLM_0308 Clostridium botulinum A2 str. Kyoto DNA polymerase III subunit epsilon YP_002802567.1 296978 D 536232 CDS YP_002802568.1 226947477 7764837 298031..298147 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 298147 7764837 CLM_0309 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802568.1 298031 D 536232 CDS YP_002802569.1 226947478 7767271 complement(298381..299055) 1 NC_012563.1 identified by match to protein family HMM PF00857; isochorismate family protein 299055 7767271 CLM_0310 Clostridium botulinum A2 str. Kyoto isochorismate family protein YP_002802569.1 298381 R 536232 CDS YP_002802570.1 226947479 7765586 300513..301004 1 NC_012563.1 xanthine dehydrogenase family protein FAD-binding subunit 301004 7765586 CLM_0313 Clostridium botulinum A2 str. Kyoto xanthine dehydrogenase family protein FAD-binding subunit YP_002802570.1 300513 D 536232 CDS YP_002802571.1 226947480 7764888 complement(301181..301534) 1 NC_012563.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02839; stage V sporulation protein AE 301534 spoVAE 7764888 spoVAE Clostridium botulinum A2 str. Kyoto stage V sporulation protein AE YP_002802571.1 301181 R 536232 CDS YP_002802572.1 226947481 7765532 complement(301557..302558) 1 NC_012563.1 identified by match to protein family HMM PF07451; match to protein family HMM TIGR02845; stage V sporulation protein AD 302558 spoVAD 7765532 spoVAD Clostridium botulinum A2 str. Kyoto stage V sporulation protein AD YP_002802572.1 301557 R 536232 CDS YP_002802573.1 226947482 7766675 complement(302559..303038) 1 NC_012563.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02838; stage V sporulation protein AC 303038 spoVAC 7766675 spoVAC Clostridium botulinum A2 str. Kyoto stage V sporulation protein AC YP_002802573.1 302559 R 536232 CDS YP_002802574.1 226947483 7768005 complement(303051..303911) 1 NC_012563.1 identified by match to protein family HMM PF04239; match to protein family HMM PF07870; hypothetical protein 303911 7768005 CLM_0317 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802574.1 303051 R 536232 CDS YP_002802575.1 226947484 7766073 complement(303924..304130) 1 NC_012563.1 identified by match to protein family HMM PF07870; hypothetical protein 304130 7766073 CLM_0318 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802575.1 303924 R 536232 CDS YP_002802576.1 226947485 7767184 304369..304572 1 NC_012563.1 identified by match to protein family HMM PF07870; hypothetical protein 304572 7767184 CLM_0319 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802576.1 304369 D 536232 CDS YP_002802577.1 226947486 7764550 305073..305543 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 305543 7764550 CLM_0320 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802577.1 305073 D 536232 CDS YP_002802578.1 226947487 7767430 305554..306237 1 NC_012563.1 identified by match to protein family HMM PF02683; DsbD family protein 306237 7767430 CLM_0321 Clostridium botulinum A2 str. Kyoto DsbD family protein YP_002802578.1 305554 D 536232 CDS YP_002802579.1 226947488 7766972 306259..306825 1 NC_012563.1 identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534; antioxidant, AhpC/TSA family 306825 7766972 CLM_0322 Clostridium botulinum A2 str. Kyoto antioxidant, AhpC/TSA family YP_002802579.1 306259 D 536232 CDS YP_002802580.1 226947489 7765687 306850..307527 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 307527 7765687 CLM_0323 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002802580.1 306850 D 536232 CDS YP_002802581.1 226947490 7767212 307664..308917 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 308917 7767212 CLM_0324 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002802581.1 307664 D 536232 CDS YP_002802582.1 226947491 7768026 complement(308983..310266) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01565; FAD binding protein 310266 7768026 CLM_0325 Clostridium botulinum A2 str. Kyoto FAD binding protein YP_002802582.1 308983 R 536232 CDS YP_002802583.1 226947492 7765616 310577..311902 1 NC_012563.1 identified by match to protein family HMM PF02056; glycosyl hydrolase, family 4 311902 7765616 CLM_0326 Clostridium botulinum A2 str. Kyoto glycosyl hydrolase, family 4 YP_002802583.1 310577 D 536232 CDS YP_002802584.1 226947493 7764545 312064..313587 1 NC_012563.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; PTS system maltose/glucose-specfic transporter subunit IIBC 313587 7764545 CLM_0327 Clostridium botulinum A2 str. Kyoto PTS system maltose/glucose-specfic transporter subunit IIBC YP_002802584.1 312064 D 536232 CDS YP_002802585.1 226947494 7766509 complement(313638..314405) 1 NC_012563.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator 314405 7766509 CLM_0328 Clostridium botulinum A2 str. Kyoto RpiR family transcriptional regulator YP_002802585.1 313638 R 536232 CDS YP_002802586.1 226947495 7765459 complement(314421..315200) 1 NC_012563.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator 315200 7765459 CLM_0329 Clostridium botulinum A2 str. Kyoto RpiR family transcriptional regulator YP_002802586.1 314421 R 536232 CDS YP_002802587.1 226947496 7764373 315476..315958 1 NC_012563.1 identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830; PTS system glucose family Etransporter subunit IIA 315958 7764373 CLM_0330 Clostridium botulinum A2 str. Kyoto PTS system glucose family Etransporter subunit IIA YP_002802587.1 315476 D 536232 CDS YP_002802588.1 226947497 7767209 316056..316832 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 316832 7767209 CLM_0331 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002802588.1 316056 D 536232 CDS YP_002802589.1 226947498 7766097 316842..317891 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 317891 7766097 CLM_0332 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002802589.1 316842 D 536232 CDS YP_002802590.1 226947499 7765000 318011..318781 1 NC_012563.1 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 318781 7765000 CLM_0333 Clostridium botulinum A2 str. Kyoto peptide ABC transporter ATP-binding protein YP_002802590.1 318011 D 536232 CDS YP_002802591.1 226947500 7766003 318795..320765 1 NC_012563.1 identified by match to protein family HMM PF02687; peptide ABC transporter permease 320765 7766003 CLM_0334 Clostridium botulinum A2 str. Kyoto peptide ABC transporter permease YP_002802591.1 318795 D 536232 CDS YP_002802592.1 226947501 7765083 321193..322764 1 NC_012563.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; PTS system glucose/glucoside family transporter subunit IIBC 322764 7765083 CLM_0335 Clostridium botulinum A2 str. Kyoto PTS system glucose/glucoside family transporter subunit IIBC YP_002802592.1 321193 D 536232 CDS YP_002802593.1 226947502 7767689 323107..324432 1 NC_012563.1 identified by similarity to SP:P54716; match to protein family HMM PF02056; maltose-6'-phosphate glucosidase 324432 glvA 7767689 glvA Clostridium botulinum A2 str. Kyoto maltose-6'-phosphate glucosidase YP_002802593.1 323107 D 536232 CDS YP_002802594.1 226947503 7766843 324607..325116 1 NC_012563.1 identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830; PTS system glucose/glucoside family transporter subunit IIA 325116 7766843 CLM_0337 Clostridium botulinum A2 str. Kyoto PTS system glucose/glucoside family transporter subunit IIA YP_002802594.1 324607 D 536232 CDS YP_002802595.1 226947504 7767147 325421..326182 1 NC_012563.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; SIS domain-containing protein 326182 7767147 CLM_0338 Clostridium botulinum A2 str. Kyoto SIS domain-containing protein YP_002802595.1 325421 D 536232 CDS YP_002802596.1 226947505 7764321 complement(326219..326401) 1 NC_012563.1 hypothetical protein 326401 7764321 CLM_0339 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802596.1 326219 R 536232 CDS YP_002802597.1 226947506 7765488 326670..326867 1 NC_012563.1 identified by match to protein family HMM PF00313; cold shock protein 326867 7765488 CLM_0340 Clostridium botulinum A2 str. Kyoto cold shock protein YP_002802597.1 326670 D 536232 CDS YP_002802598.1 226947507 7766348 327209..327763 1 NC_012563.1 identified by match to protein family HMM PF06210; hypothetical protein 327763 7766348 CLM_0341 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802598.1 327209 D 536232 CDS YP_002802599.1 226947508 7767788 328198..328629 1 NC_012563.1 identified by match to protein family HMM PF02082; rrf2 family protein 328629 7767788 CLM_0342 Clostridium botulinum A2 str. Kyoto rrf2 family protein YP_002802599.1 328198 D 536232 CDS YP_002802600.1 226947509 7765789 328781..329386 1 NC_012563.1 identified by match to protein family HMM PF01323; DSBA-like thioredoxin domain-containing protein 329386 7765789 CLM_0343 Clostridium botulinum A2 str. Kyoto DSBA-like thioredoxin domain-containing protein YP_002802600.1 328781 D 536232 CDS YP_002802601.1 226947510 7765960 329413..330051 1 NC_012563.1 hypothetical protein 330051 7765960 CLM_0344 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802601.1 329413 D 536232 CDS YP_002802602.1 226947511 7766798 330489..331250 1 NC_012563.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator 331250 7766798 CLM_0345 Clostridium botulinum A2 str. Kyoto RpiR family transcriptional regulator YP_002802602.1 330489 D 536232 CDS YP_002802603.1 226947512 7766215 331369..332952 1 NC_012563.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; PTS system glucose/maltose-specfic transporter subunit IIBC 332952 7766215 CLM_0346 Clostridium botulinum A2 str. Kyoto PTS system glucose/maltose-specfic transporter subunit IIBC YP_002802603.1 331369 D 536232 CDS YP_002802604.1 226947513 7765098 333348..334682 1 NC_012563.1 identified by similarity to SP:P54716; match to protein family HMM PF02056; maltose-6'-phosphate glucosidase 334682 glvA 7765098 glvA Clostridium botulinum A2 str. Kyoto maltose-6'-phosphate glucosidase YP_002802604.1 333348 D 536232 CDS YP_002802605.1 226947514 7765546 334695..335168 1 NC_012563.1 identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830; PTS system glucose family transporter subunit IIA 335168 7765546 CLM_0348 Clostridium botulinum A2 str. Kyoto PTS system glucose family transporter subunit IIA YP_002802605.1 334695 D 536232 CDS YP_002802606.1 226947515 7766623 335306..337021 1 NC_012563.1 identified by match to protein family HMM PF00920; dihydroxy-acid dehydratase 337021 ilvD 7766623 ilvD Clostridium botulinum A2 str. Kyoto dihydroxy-acid dehydratase YP_002802606.1 335306 D 536232 CDS YP_002802607.1 226947516 7764224 337073..337720 1 NC_012563.1 identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 337720 eda 7764224 eda Clostridium botulinum A2 str. Kyoto 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase YP_002802607.1 337073 D 536232 CDS YP_002802608.1 226947517 7765552 337722..338726 1 NC_012563.1 identified by match to protein family HMM PF00294; PfkB family kinase 338726 7765552 CLM_0351 Clostridium botulinum A2 str. Kyoto PfkB family kinase YP_002802608.1 337722 D 536232 CDS YP_002802609.1 226947518 7767105 338927..340780 1 NC_012563.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR01178; adenine deaminase 340780 ade 7767105 ade Clostridium botulinum A2 str. Kyoto adenine deaminase YP_002802609.1 338927 D 536232 CDS YP_002802610.1 226947519 7767319 341182..341856 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 341856 7767319 CLM_0353 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002802610.1 341182 D 536232 CDS YP_002802611.1 226947520 7765764 341853..343241 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 343241 7765764 CLM_0354 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002802611.1 341853 D 536232 CDS YP_002802612.1 226947521 7767145 343637..344605 1 NC_012563.1 identified by match to protein family HMM PF00535; group 2 family glycosyl transferase 344605 7767145 CLM_0355 Clostridium botulinum A2 str. Kyoto group 2 family glycosyl transferase YP_002802612.1 343637 D 536232 CDS YP_002802613.1 226947522 7766621 344589..345008 1 NC_012563.1 identified by match to protein family HMM PF04138; putative cell wall teichoic acid glycosylation protein GtcA 345008 7766621 CLM_0356 Clostridium botulinum A2 str. Kyoto putative cell wall teichoic acid glycosylation protein GtcA YP_002802613.1 344589 D 536232 CDS YP_002802614.1 226947523 7767527 345127..347406 1 NC_012563.1 identified by match to protein family HMM PF02366; dolichyl-phosphate-mannose-protein mannosyltransferase family protein 347406 7767527 CLM_0357 Clostridium botulinum A2 str. Kyoto dolichyl-phosphate-mannose-protein mannosyltransferase family protein YP_002802614.1 345127 D 536232 CDS YP_002802615.1 226947524 7766076 347762..348799 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 348799 7766076 CLM_0358 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002802615.1 347762 D 536232 CDS YP_002802616.1 226947525 7764953 349064..350095 1 NC_012563.1 identified by match to protein family HMM PF01497; iron chelate uptake ABC transporter solute-binding protein 350095 7764953 CLM_0359 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter solute-binding protein YP_002802616.1 349064 D 536232 CDS YP_002802617.1 226947526 7765599 351218..351988 1 NC_012563.1 identified by match to protein family HMM PF00005; iron chelate uptake ABC transporter ATP-binding protein 351988 7765599 CLM_0362 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter ATP-binding protein YP_002802617.1 351218 D 536232 CDS YP_002802618.1 226947527 7764233 352022..353392 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 353392 7764233 CLM_0363 Clostridium botulinum A2 str. Kyoto mate efflux family protein YP_002802618.1 352022 D 536232 CDS YP_002802619.1 226947528 7766396 353883..353999 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 353999 7766396 CLM_0364 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802619.1 353883 D 536232 CDS YP_002802620.1 226947529 7767133 354013..354735 1 NC_012563.1 identified by match to protein family HMM PF01648; match to protein family HMM TIGR00556; 4'-phosphopantetheinyl transferase sfp 354735 7767133 CLM_0365 Clostridium botulinum A2 str. Kyoto 4'-phosphopantetheinyl transferase sfp YP_002802620.1 354013 D 536232 CDS YP_002802621.1 226947530 7765765 354759..355475 1 NC_012563.1 identified by match to protein family HMM PF00975; linear gramicidin dehydrogenase LgrE 355475 7765765 CLM_0366 Clostridium botulinum A2 str. Kyoto linear gramicidin dehydrogenase LgrE YP_002802621.1 354759 D 536232 CDS YP_002802622.1 226947531 7764868 355732..356472 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; two component transcriptional regulator, LytTR family 356472 7764868 CLM_0367 Clostridium botulinum A2 str. Kyoto two component transcriptional regulator, LytTR family YP_002802622.1 355732 D 536232 CDS YP_002802623.1 226947532 7765019 356484..357785 1 NC_012563.1 identified by similarity to GB:AAA58950.1; VirS-like protein 357785 7765019 CLM_0368 Clostridium botulinum A2 str. Kyoto VirS-like protein YP_002802623.1 356484 D 536232 CDS YP_002802624.1 226947533 7767904 358533..363017 1 NC_012563.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733; nonribosomal peptide synthetase subunit 363017 7767904 CLM_0369 Clostridium botulinum A2 str. Kyoto nonribosomal peptide synthetase subunit YP_002802624.1 358533 D 536232 CDS YP_002802625.1 226947534 7767784 363192..363575 1 NC_012563.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 363575 panD 7767784 panD Clostridium botulinum A2 str. Kyoto aspartate alpha-decarboxylase YP_002802625.1 363192 D 536232 CDS YP_002802626.1 226947535 7766913 363732..365243 1 NC_012563.1 identified by match to protein family HMM PF00144; beta-lactamase 365243 7766913 CLM_0371 Clostridium botulinum A2 str. Kyoto beta-lactamase YP_002802626.1 363732 D 536232 CDS YP_002802627.1 226947536 7764497 365336..365476 1 NC_012563.1 identified by similarity to SP:P33951; hypothetical protein 365476 7764497 CLM_0372 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802627.1 365336 D 536232 CDS YP_002802628.1 226947537 7767590 365497..376245 1 NC_012563.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733; AMP-binding protein domain-containing protein 376245 7767590 CLM_0373 Clostridium botulinum A2 str. Kyoto AMP-binding protein domain-containing protein YP_002802628.1 365497 D 536232 CDS YP_002802629.1 226947538 7765250 376355..387913 1 NC_012563.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733; amino acid adenylation domain-containing protein 387913 7765250 CLM_0374 Clostridium botulinum A2 str. Kyoto amino acid adenylation domain-containing protein YP_002802629.1 376355 D 536232 CDS YP_002802630.1 226947539 7765131 388054..396384 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00975; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733; bacitracin synthetase 1 396384 7765131 CLM_0375 Clostridium botulinum A2 str. Kyoto bacitracin synthetase 1 YP_002802630.1 388054 D 536232 CDS YP_002802631.1 226947540 7767807 396535..397152 1 NC_012563.1 identified by match to protein family HMM PF01554; mate efflux family protein 397152 7767807 CLM_0376 Clostridium botulinum A2 str. Kyoto mate efflux family protein YP_002802631.1 396535 D 536232 CDS YP_002802632.1 226947541 7766666 complement(397285..398256) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00165; AraC family transcriptional regulator 398256 7766666 CLM_0377 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002802632.1 397285 R 536232 CDS YP_002802633.1 226947542 7767731 398654..399592 1 NC_012563.1 identified by match to protein family HMM PF01497; iron compound ABC transporter iron compound-binding protein 399592 7767731 CLM_0378 Clostridium botulinum A2 str. Kyoto iron compound ABC transporter iron compound-binding protein YP_002802633.1 398654 D 536232 CDS YP_002802634.1 226947543 7765168 399795..400823 1 NC_012563.1 identified by match to protein family HMM PF01032; ferrichrome transport system permease FhuB 400823 7765168 CLM_0379 Clostridium botulinum A2 str. Kyoto ferrichrome transport system permease FhuB YP_002802634.1 399795 D 536232 CDS YP_002802635.1 226947544 7765966 400820..401827 1 NC_012563.1 identified by match to protein family HMM PF01032; ferrichrome transport system permease FhuG 401827 7765966 CLM_0380 Clostridium botulinum A2 str. Kyoto ferrichrome transport system permease FhuG YP_002802635.1 400820 D 536232 CDS YP_002802636.1 226947545 7766288 401861..402685 1 NC_012563.1 identified by match to protein family HMM PF00005; ferrichrome transport ATP-binding protein FhuC 402685 7766288 CLM_0381 Clostridium botulinum A2 str. Kyoto ferrichrome transport ATP-binding protein FhuC YP_002802636.1 401861 D 536232 CDS YP_002802637.1 226947546 7767616 402682..404409 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; lipid A export ATP-binding/permease MsbA 404409 7767616 CLM_0382 Clostridium botulinum A2 str. Kyoto lipid A export ATP-binding/permease MsbA YP_002802637.1 402682 D 536232 CDS YP_002802638.1 226947547 7764606 404911..406212 1 NC_012563.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine/uracil permease family protein 406212 7764606 CLM_0384 Clostridium botulinum A2 str. Kyoto xanthine/uracil permease family protein YP_002802638.1 404911 D 536232 CDS YP_002802639.1 226947548 7764865 406235..406807 1 NC_012563.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 406807 xpt 7764865 xpt Clostridium botulinum A2 str. Kyoto xanthine phosphoribosyltransferase YP_002802639.1 406235 D 536232 CDS YP_002802640.1 226947549 7767792 407255..407947 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 407947 7767792 CLM_0386 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002802640.1 407255 D 536232 CDS YP_002802641.1 226947550 7767097 407960..408940 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 408940 7767097 CLM_0387 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002802641.1 407960 D 536232 CDS YP_002802642.1 226947551 7767970 409116..409973 1 NC_012563.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 409973 uppP 7767970 uppP Clostridium botulinum A2 str. Kyoto UDP pyrophosphate phosphatase YP_002802642.1 409116 D 536232 CDS YP_002802643.1 226947552 7766262 409988..410734 1 NC_012563.1 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 410734 7766262 CLM_0389 Clostridium botulinum A2 str. Kyoto peptide ABC transporter ATP-binding protein YP_002802643.1 409988 D 536232 CDS YP_002802644.1 226947553 7765623 410734..412596 1 NC_012563.1 identified by match to protein family HMM PF02687; peptide ABC transporter permease 412596 7765623 CLM_0390 Clostridium botulinum A2 str. Kyoto peptide ABC transporter permease YP_002802644.1 410734 D 536232 CDS YP_002802645.1 226947554 7766660 412721..413128 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 413128 7766660 CLM_0391 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802645.1 412721 D 536232 CDS YP_002802646.1 226947555 7765312 413455..413811 1 NC_012563.1 identified by match to protein family HMM PF03788; lrgA family protein 413811 7765312 CLM_0392 Clostridium botulinum A2 str. Kyoto lrgA family protein YP_002802646.1 413455 D 536232 CDS YP_002802647.1 226947556 7764441 413814..414509 1 NC_012563.1 identified by match to protein family HMM PF04172; lrgB family protein 414509 7764441 CLM_0393 Clostridium botulinum A2 str. Kyoto lrgB family protein YP_002802647.1 413814 D 536232 CDS YP_002802648.1 226947557 7767035 414805..415455 1 NC_012563.1 putative lipoprotein 415455 7767035 CLM_0394 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002802648.1 414805 D 536232 CDS YP_002802649.1 226947558 7765689 415824..416723 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 416723 7765689 CLM_0395 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002802649.1 415824 D 536232 CDS YP_002802650.1 226947559 7764805 416858..418366 1 NC_012563.1 identified by match to protein family HMM PF08903; hypothetical protein 418366 7764805 CLM_0396 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802650.1 416858 D 536232 CDS YP_002802651.1 226947560 7767553 418690..419241 1 NC_012563.1 hypothetical protein 419241 7767553 CLM_0397 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802651.1 418690 D 536232 CDS YP_002802652.1 226947561 7766470 419420..419887 1 NC_012563.1 hypothetical protein 419887 7766470 CLM_0398 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802652.1 419420 D 536232 CDS YP_002802653.1 226947562 7764360 419880..420569 1 NC_012563.1 identified by match to protein family HMM PF04647; putative accessory gene regulator protein B 420569 7764360 CLM_0399 Clostridium botulinum A2 str. Kyoto putative accessory gene regulator protein B YP_002802653.1 419880 D 536232 CDS YP_002802654.1 226947563 7765601 420553..420687 1 NC_012563.1 putative lipoprotein 420687 7765601 CLM_0400 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002802654.1 420553 D 536232 CDS YP_002802655.1 226947564 7768124 420759..422462 1 NC_012563.1 identified by match to protein family HMM PF00990; match to protein family HMM PF01966; match to protein family HMM TIGR00254; GGDEF/HD domain-containing protein 422462 7768124 CLM_0401 Clostridium botulinum A2 str. Kyoto GGDEF/HD domain-containing protein YP_002802655.1 420759 D 536232 CDS YP_002802656.1 226947565 7767283 422693..423202 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 423202 7767283 CLM_0402 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002802656.1 422693 D 536232 CDS YP_002802657.1 226947566 7767571 423600..424052 1 NC_012563.1 hypothetical protein 424052 7767571 CLM_0403 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802657.1 423600 D 536232 CDS YP_002802658.1 226947567 7766434 424079..425926 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase 425926 7766434 CLM_0404 Clostridium botulinum A2 str. Kyoto sensory box histidine kinase YP_002802658.1 424079 D 536232 CDS YP_002802659.1 226947568 7765851 426186..426623 1 NC_012563.1 hypothetical protein 426623 7765851 CLM_0405 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802659.1 426186 D 536232 CDS YP_002802660.1 226947569 7764764 426610..427239 1 NC_012563.1 identified by match to protein family HMM PF04647; putative accessory gene regulator protein B 427239 7764764 CLM_0406 Clostridium botulinum A2 str. Kyoto putative accessory gene regulator protein B YP_002802660.1 426610 D 536232 CDS YP_002802661.1 226947570 7765041 427334..427468 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 427468 7765041 CLM_0407 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802661.1 427334 D 536232 CDS YP_002802662.1 226947571 7767804 427551..429404 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase 429404 7767804 CLM_0408 Clostridium botulinum A2 str. Kyoto sensory box histidine kinase YP_002802662.1 427551 D 536232 CDS YP_002802663.1 226947572 7764502 429636..430502 1 NC_012563.1 identified by match to protein family HMM PF01171; PP-loop family protein 430502 7764502 CLM_0409 Clostridium botulinum A2 str. Kyoto PP-loop family protein YP_002802663.1 429636 D 536232 CDS YP_002802664.1 226947573 7767301 complement(430626..431171) 1 NC_012563.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883; DNA-binding protein 431171 7767301 CLM_0410 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002802664.1 430626 R 536232 CDS YP_002802665.1 226947574 7767833 431526..432932 1 NC_012563.1 identified by match to protein family HMM PF00324; amino acid permease family protein 432932 7767833 CLM_0411 Clostridium botulinum A2 str. Kyoto amino acid permease family protein YP_002802665.1 431526 D 536232 CDS YP_002802666.1 226947575 7766692 433051..434133 1 NC_012563.1 identified by match to protein family HMM PF00557; metallopeptidase, family M24 434133 7766692 CLM_0412 Clostridium botulinum A2 str. Kyoto metallopeptidase, family M24 YP_002802666.1 433051 D 536232 CDS YP_002802667.1 226947576 7764554 434540..437128 1 NC_012563.1 identified by match to protein family HMM PF00171; match to protein family HMM PF00465; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 437128 adhE 7764554 adhE Clostridium botulinum A2 str. Kyoto bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002802667.1 434540 D 536232 CDS YP_002802668.1 226947577 7767927 437447..437734 1 NC_012563.1 hypothetical protein 437734 7767927 CLM_0414 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802668.1 437447 D 536232 CDS YP_002802669.1 226947578 7765195 437797..438387 1 NC_012563.1 hypothetical protein 438387 7765195 CLM_0415 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802669.1 437797 D 536232 CDS YP_002802670.1 226947579 7764429 complement(438673..439152) 1 NC_012563.1 hypothetical protein 439152 7764429 CLM_0416 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802670.1 438673 R 536232 CDS YP_002802671.1 226947580 7767503 complement(439400..440410) 1 NC_012563.1 hypothetical protein 440410 7767503 CLM_0417 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802671.1 439400 R 536232 CDS YP_002802672.1 226947581 7766598 440514..441041 1 NC_012563.1 identified by match to protein family HMM PF01569; PAP2 family protein 441041 7766598 CLM_0418 Clostridium botulinum A2 str. Kyoto PAP2 family protein YP_002802672.1 440514 D 536232 CDS YP_002802673.1 226947582 7764762 441595..442407 1 NC_012563.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 442407 7764762 CLM_0419 Clostridium botulinum A2 str. Kyoto polysaccharide deacetylase family protein YP_002802673.1 441595 D 536232 CDS YP_002802674.1 226947583 7767954 442515..443201 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 443201 7767954 CLM_0420 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002802674.1 442515 D 536232 CDS YP_002802675.1 226947584 7765331 443211..444605 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 444605 7765331 CLM_0421 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002802675.1 443211 D 536232 CDS YP_002802676.1 226947585 7765232 444668..446158 1 NC_012563.1 putative lipoprotein 446158 7765232 CLM_0422 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002802676.1 444668 D 536232 CDS YP_002802677.1 226947586 7767232 446202..446768 1 NC_012563.1 identified by match to protein family HMM PF06962; hypothetical protein 446768 7767232 CLM_0423 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802677.1 446202 D 536232 CDS YP_002802678.1 226947587 7766328 446794..447468 1 NC_012563.1 identified by match to protein family HMM PF09335; DedA family protein 447468 7766328 CLM_0424 Clostridium botulinum A2 str. Kyoto DedA family protein YP_002802678.1 446794 D 536232 CDS YP_002802679.1 226947588 7766981 complement(447598..450129) 1 NC_012563.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00672; match to protein family HMM PF00990; match to protein family HMM PF05228; match to protein family HMM TIGR00254; multisensor diguanylate cyclase/phophodiesterase 450129 7766981 CLM_0425 Clostridium botulinum A2 str. Kyoto multisensor diguanylate cyclase/phophodiesterase YP_002802679.1 447598 R 536232 CDS YP_002802680.1 226947589 7766120 complement(450474..451661) 1 NC_012563.1 hypothetical protein 451661 7766120 CLM_0426 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802680.1 450474 R 536232 CDS YP_002802681.1 226947590 7765880 451914..453254 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; MATE efflux family protein 453254 7765880 CLM_0427 Clostridium botulinum A2 str. Kyoto MATE efflux family protein YP_002802681.1 451914 D 536232 CDS YP_002802682.1 226947591 7764513 453446..454012 1 NC_012563.1 identified by match to protein family HMM PF01966; HD domain-containing protein 454012 7764513 CLM_0428 Clostridium botulinum A2 str. Kyoto HD domain-containing protein YP_002802682.1 453446 D 536232 CDS YP_002802683.1 226947592 7767650 454324..455592 1 NC_012563.1 identified by match to protein family HMM PF00999; CPA2 family transporter 455592 7767650 CLM_0429 Clostridium botulinum A2 str. Kyoto CPA2 family transporter YP_002802683.1 454324 D 536232 CDS YP_002802684.1 226947593 7766537 complement(455727..457049) 1 NC_012563.1 identified by match to protein family HMM PF00266; class V aminotransferase 457049 7766537 CLM_0430 Clostridium botulinum A2 str. Kyoto class V aminotransferase YP_002802684.1 455727 R 536232 CDS YP_002802685.1 226947594 7766645 457436..458446 1 NC_012563.1 identified by match to protein family HMM PF03601; hypothetical protein 458446 7766645 CLM_0431 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802685.1 457436 D 536232 CDS YP_002802686.1 226947595 7764980 458577..459251 1 NC_012563.1 hypothetical protein 459251 7764980 CLM_0432 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802686.1 458577 D 536232 CDS YP_002802687.1 226947596 7767359 459197..459895 1 NC_012563.1 identified by match to protein family HMM PF00486; DNA-binding response regulator 459895 7767359 CLM_0433 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002802687.1 459197 D 536232 CDS YP_002802688.1 226947597 7766080 459885..461399 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 461399 7766080 CLM_0434 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002802688.1 459885 D 536232 CDS YP_002802689.1 226947598 7764998 461507..462922 1 NC_012563.1 identified by match to protein family HMM PF00474; sodium:solute symporter family protein 462922 7764998 CLM_0435 Clostridium botulinum A2 str. Kyoto sodium:solute symporter family protein YP_002802689.1 461507 D 536232 CDS YP_002802690.1 226947599 7767867 464152..465471 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01512; match to protein family HMM TIGR01945; RnfABCDGE type electron transport complex subunit C 465471 7767867 CLM_0436 Clostridium botulinum A2 str. Kyoto RnfABCDGE type electron transport complex subunit C YP_002802690.1 464152 D 536232 CDS YP_002802691.1 226947600 7766735 465494..466426 1 NC_012563.1 identified by match to protein family HMM PF03116; match to protein family HMM TIGR01946; RnfABCDGE type electron transport complex subunit D 466426 7766735 CLM_0437 Clostridium botulinum A2 str. Kyoto RnfABCDGE type electron transport complex subunit D YP_002802691.1 465494 D 536232 CDS YP_002802692.1 226947601 7764544 466426..467097 1 NC_012563.1 identified by match to protein family HMM PF04205; match to protein family HMM TIGR01947; RnfABCDGE type electron transport complex subunit G 467097 7764544 CLM_0438 Clostridium botulinum A2 str. Kyoto RnfABCDGE type electron transport complex subunit G YP_002802692.1 466426 D 536232 CDS YP_002802693.1 226947602 7765589 467108..467710 1 NC_012563.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 467710 7765589 CLM_0439 Clostridium botulinum A2 str. Kyoto electron transport complex RsxE subunit YP_002802693.1 467108 D 536232 CDS YP_002802694.1 226947603 7766157 467761..468339 1 NC_012563.1 identified by match to protein family HMM PF02508; match to protein family HMM TIGR01943; RnfABCDGE type electron transport complex subunit A 468339 7766157 CLM_0440 Clostridium botulinum A2 str. Kyoto RnfABCDGE type electron transport complex subunit A YP_002802694.1 467761 D 536232 CDS YP_002802695.1 226947604 7767300 468353..469186 1 NC_012563.1 involved in the electron transport chain; in Methanosarcina acetivorans this protein is part of a cluster involved in electron transfer during growth on acetate; ferredoxin 469186 7767300 CLM_0441 Clostridium botulinum A2 str. Kyoto ferredoxin YP_002802695.1 468353 D 536232 CDS YP_002802696.1 226947605 7766687 469548..470636 1 NC_012563.1 identified by match to protein family HMM PF04122; amidase domain-containing protein 470636 7766687 CLM_0442 Clostridium botulinum A2 str. Kyoto amidase domain-containing protein YP_002802696.1 469548 D 536232 CDS YP_002802697.1 226947606 7767734 complement(470788..471324) 1 NC_012563.1 identified by match to protein family HMM PF07456; hypothetical protein 471324 7767734 CLM_0443 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802697.1 470788 R 536232 CDS YP_002802698.1 226947607 7764530 complement(471342..471734) 1 NC_012563.1 identified by match to protein family HMM PF07009; hypothetical protein 471734 7764530 CLM_0444 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802698.1 471342 R 536232 CDS YP_002802699.1 226947608 7765438 complement(471848..472882) 1 NC_012563.1 identified by match to protein family HMM PF02424; apbE family protein 472882 7765438 CLM_0445 Clostridium botulinum A2 str. Kyoto apbE family protein YP_002802699.1 471848 R 536232 CDS YP_002802700.1 226947609 7767170 473491..477642 1 NC_012563.1 identified by match to protein family HMM PF04122; cell Surface protein 477642 7767170 CLM_0446 Clostridium botulinum A2 str. Kyoto cell Surface protein YP_002802700.1 473491 D 536232 CDS YP_002802701.1 226947610 7764522 478128..480197 1 NC_012563.1 identified by match to protein family HMM PF04122; match to protein family HMM PF04151; amidase domain-containing protein 480197 7764522 CLM_0447 Clostridium botulinum A2 str. Kyoto amidase domain-containing protein YP_002802701.1 478128 D 536232 CDS YP_002802702.1 226947611 7766885 480290..480520 1 NC_012563.1 hypothetical protein 480520 7766885 CLM_0448 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802702.1 480290 D 536232 CDS YP_002802703.1 226947612 7764605 480841..485745 1 NC_012563.1 identified by match to protein family HMM PF04122; putative cell surface protein 485745 7764605 CLM_0449 Clostridium botulinum A2 str. Kyoto putative cell surface protein YP_002802703.1 480841 D 536232 CDS YP_002802704.1 226947613 7765150 complement(485816..486250) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 486250 7765150 CLM_0450 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802704.1 485816 R 536232 CDS YP_002802705.1 226947614 7766023 486567..490079 1 NC_012563.1 identified by match to protein family HMM PF04122; putative cell wall-binding protease 490079 7766023 CLM_0451 Clostridium botulinum A2 str. Kyoto putative cell wall-binding protease YP_002802705.1 486567 D 536232 CDS YP_002802706.1 226947615 7766326 complement(490165..491196) 1 NC_012563.1 acyltransferase family protein 491196 7766326 CLM_0452 Clostridium botulinum A2 str. Kyoto acyltransferase family protein YP_002802706.1 490165 R 536232 CDS YP_002802707.1 226947616 7767193 491764..493275 1 NC_012563.1 hypothetical protein 493275 7767193 CLM_0453 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802707.1 491764 D 536232 CDS YP_002802708.1 226947617 7766376 493670..494581 1 NC_012563.1 phosphate ABC transporter substrate-binding protein 494581 7766376 CLM_0454 Clostridium botulinum A2 str. Kyoto phosphate ABC transporter substrate-binding protein YP_002802708.1 493670 D 536232 CDS YP_002802709.1 226947618 7767249 494786..495649 1 NC_012563.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 495649 7767249 CLM_0455 Clostridium botulinum A2 str. Kyoto phosphate ABC transporter permease YP_002802709.1 494786 D 536232 CDS YP_002802710.1 226947619 7764629 495685..496515 1 NC_012563.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 496515 7764629 CLM_0456 Clostridium botulinum A2 str. Kyoto phosphate ABC transporter permease YP_002802710.1 495685 D 536232 CDS YP_002802711.1 226947620 7765490 496517..497263 1 NC_012563.1 identified by match to protein family HMM PF00005; phosphate uptake ABC transporter ATP-binding protein 497263 7765490 CLM_0457 Clostridium botulinum A2 str. Kyoto phosphate uptake ABC transporter ATP-binding protein YP_002802711.1 496517 D 536232 CDS YP_002802712.1 226947621 7764533 497384..497854 1 NC_012563.1 hypothetical protein 497854 7764533 CLM_0458 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802712.1 497384 D 536232 CDS YP_002802713.1 226947622 7767343 498209..499660 1 NC_012563.1 identified by match to protein family HMM PF00324; amino acid permease family protein 499660 7767343 CLM_0459 Clostridium botulinum A2 str. Kyoto amino acid permease family protein YP_002802713.1 498209 D 536232 CDS YP_002802714.1 226947623 7766243 complement(499728..500309) 1 NC_012563.1 identified by match to protein family HMM PF09580; match to protein family HMM TIGR02898; sporulation lipoprotein, YhcN/YlaJ family 500309 7766243 CLM_0460 Clostridium botulinum A2 str. Kyoto sporulation lipoprotein, YhcN/YlaJ family YP_002802714.1 499728 R 536232 CDS YP_002802715.1 226947624 7766140 500498..501322 1 NC_012563.1 hypothetical protein 501322 7766140 CLM_0461 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802715.1 500498 D 536232 CDS YP_002802716.1 226947625 7764990 501400..502095 1 NC_012563.1 identified by match to protein family HMM PF01863; hypothetical protein 502095 7764990 CLM_0462 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802716.1 501400 D 536232 CDS YP_002802717.1 226947626 7767868 502182..502520 1 NC_012563.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-strand binding domain-containing protein 502520 7767868 CLM_0463 Clostridium botulinum A2 str. Kyoto single-strand binding domain-containing protein YP_002802717.1 502182 D 536232 CDS YP_002802718.1 226947627 7765592 502774..503325 1 NC_012563.1 identified by match to protein family HMM PF02659; hypothetical protein 503325 7765592 CLM_0464 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802718.1 502774 D 536232 CDS YP_002802719.1 226947628 7764562 503389..503823 1 NC_012563.1 identified by match to protein family HMM PF01475; Fur family transcriptional regulator 503823 7764562 CLM_0466 Clostridium botulinum A2 str. Kyoto Fur family transcriptional regulator YP_002802719.1 503389 D 536232 CDS YP_002802720.1 226947629 7767007 complement(503820..504167) 1 NC_012563.1 exported protein 504167 7767007 CLM_0465 Clostridium botulinum A2 str. Kyoto exported protein YP_002802720.1 503820 R 536232 CDS YP_002802721.1 226947630 7767392 504420..505496 1 NC_012563.1 identified by match to protein family HMM PF01966; HD domain-containing protein 505496 7767392 CLM_0467 Clostridium botulinum A2 str. Kyoto HD domain-containing protein YP_002802721.1 504420 D 536232 CDS YP_002802722.1 226947631 7766419 505633..506655 1 NC_012563.1 identified by match to protein family HMM PF01694; peptidase, S54 506655 7766419 CLM_0468 Clostridium botulinum A2 str. Kyoto peptidase, S54 YP_002802722.1 505633 D 536232 CDS YP_002802723.1 226947632 7765770 complement(506825..508879) 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 508879 7765770 CLM_0469 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002802723.1 506825 R 536232 CDS YP_002802724.1 226947633 7765101 complement(509839..511569) 1 NC_012563.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM PF07728; match to protein family HMM TIGR01241; ATP-dependent metalloprotease 511569 7765101 CLM_0470 Clostridium botulinum A2 str. Kyoto ATP-dependent metalloprotease YP_002802724.1 509839 R 536232 CDS YP_002802725.1 226947634 7767936 511789..512844 1 NC_012563.1 identified by match to protein family HMM PF06803; hypothetical protein 512844 7767936 CLM_0471 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802725.1 511789 D 536232 CDS YP_002802726.1 226947635 7767395 512819..513268 1 NC_012563.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 513268 rnhA 7767395 rnhA Clostridium botulinum A2 str. Kyoto ribonuclease H YP_002802726.1 512819 D 536232 CDS YP_002802727.1 226947636 7766265 513331..513507 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 513507 7766265 CLM_0473 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802727.1 513331 D 536232 CDS YP_002802728.1 226947637 7765571 513689..514993 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF01381; hypothetical protein 514993 7765571 CLM_0474 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802728.1 513689 D 536232 CDS YP_002802729.1 226947638 7764449 515025..516278 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein 516278 7764449 CLM_0475 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802729.1 515025 D 536232 CDS YP_002802730.1 226947639 7767946 516723..516902 1 NC_012563.1 hypothetical protein 516902 7767946 CLM_0476 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802730.1 516723 D 536232 CDS YP_002802731.1 226947640 7767115 516933..517538 1 NC_012563.1 identified by match to protein family HMM PF01965; DJ-1/PfpI family protein 517538 7767115 CLM_0477 Clostridium botulinum A2 str. Kyoto DJ-1/PfpI family protein YP_002802731.1 516933 D 536232 CDS YP_002802732.1 226947641 7765978 complement(517650..518033) 1 NC_012563.1 hypothetical protein 518033 7765978 CLM_0478 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802732.1 517650 R 536232 CDS YP_002802733.1 226947642 7766748 518068..518673 1 NC_012563.1 hypothetical protein 518673 7766748 CLM_0479 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802733.1 518068 D 536232 CDS YP_002802734.1 226947643 7766198 519037..521637 1 NC_012563.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346; clpB protein 521637 clpB 7766198 clpB Clostridium botulinum A2 str. Kyoto clpB protein YP_002802734.1 519037 D 536232 CDS YP_002802735.1 226947644 7764982 complement(521927..522655) 1 NC_012563.1 identified by match to protein family HMM PF07685; glutamine amidotransferase, CobB/CobQ family 522655 7764982 CLM_0481 Clostridium botulinum A2 str. Kyoto glutamine amidotransferase, CobB/CobQ family YP_002802735.1 521927 R 536232 CDS YP_002802736.1 226947645 7764556 complement(522713..524074) 1 NC_012563.1 identified by match to protein family HMM PF08245; match to protein family HMM PF08353; UDP-N-acetylmuramyl tripeptide synthetase-like protein 524074 7764556 CLM_0482 Clostridium botulinum A2 str. Kyoto UDP-N-acetylmuramyl tripeptide synthetase-like protein YP_002802736.1 522713 R 536232 CDS YP_002802737.1 226947646 7765481 524339..525319 1 NC_012563.1 identified by match to protein family HMM PF01238; mannose-6-phosphate isomerase, class I 525319 manA 7765481 manA Clostridium botulinum A2 str. Kyoto mannose-6-phosphate isomerase, class I YP_002802737.1 524339 D 536232 CDS YP_002802738.1 226947647 7766903 525668..526783 1 NC_012563.1 putative lipoprotein 526783 7766903 CLM_0484 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002802738.1 525668 D 536232 CDS YP_002802739.1 226947648 7767755 526891..527745 1 NC_012563.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 527745 7767755 CLM_0485 Clostridium botulinum A2 str. Kyoto UDP pyrophosphate phosphatase YP_002802739.1 526891 D 536232 CDS YP_002802740.1 226947649 7768159 complement(531367..531822) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 531822 7768159 CLM_0489 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802740.1 531367 R 536232 CDS YP_002802741.1 226947650 7767782 complement(531896..532552) 1 NC_012563.1 hypothetical protein 532552 7767782 CLM_0490 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802741.1 531896 R 536232 CDS YP_002802742.1 226947651 7768226 complement(533717..534580) 1 NC_012563.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 534580 7768226 CLM_0494 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002802742.1 533717 R 536232 CDS YP_002802743.1 226947652 7766988 534717..535439 1 NC_012563.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530; putative 1-acyl-sn-glycerol-3-phosphate acyltransferase 535439 7766988 CLM_0495 Clostridium botulinum A2 str. Kyoto putative 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_002802743.1 534717 D 536232 CDS YP_002802744.1 226947653 7764565 536185..537546 1 NC_012563.1 identified by match to protein family HMM PF00682; HMGL-related enzyme 537546 7764565 CLM_0496 Clostridium botulinum A2 str. Kyoto HMGL-related enzyme YP_002802744.1 536185 D 536232 CDS YP_002802745.1 226947654 7765259 537690..539615 1 NC_012563.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 539615 7765259 CLM_0497 Clostridium botulinum A2 str. Kyoto aconitate hydratase YP_002802745.1 537690 D 536232 CDS YP_002802746.1 226947655 7766976 539818..540816 1 NC_012563.1 identified by match to protein family HMM PF00180; dehydrogenase 540816 7766976 CLM_0498 Clostridium botulinum A2 str. Kyoto dehydrogenase YP_002802746.1 539818 D 536232 CDS YP_002802747.1 226947656 7768075 541066..541848 1 NC_012563.1 identified by match to protein family HMM PF00005; polar amino acid uptake family ABC transporter ATP-binding protein 541848 7768075 CLM_0499 Clostridium botulinum A2 str. Kyoto polar amino acid uptake family ABC transporter ATP-binding protein YP_002802747.1 541066 D 536232 CDS YP_002802748.1 226947657 7765656 542371..544137 1 NC_012563.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03606; Na+/H+ antiporter family protein 544137 7765656 CLM_0501 Clostridium botulinum A2 str. Kyoto Na+/H+ antiporter family protein YP_002802748.1 542371 D 536232 CDS YP_002802749.1 226947658 7765734 complement(544164..544379) 1 NC_012563.1 identified by match to protein family HMM PF04070; hypothetical protein 544379 7765734 CLM_0502 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802749.1 544164 R 536232 CDS YP_002802750.1 226947659 7766359 complement(544467..544850) 1 NC_012563.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 544850 panD 7766359 panD Clostridium botulinum A2 str. Kyoto aspartate alpha-decarboxylase YP_002802750.1 544467 R 536232 CDS YP_002802751.1 226947660 7767229 complement(544976..545821) 1 NC_012563.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 545821 panC 7767229 panC Clostridium botulinum A2 str. Kyoto pantoate--beta-alanine ligase YP_002802751.1 544976 R 536232 CDS YP_002802752.1 226947661 7768080 complement(545876..546703) 1 NC_012563.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 546703 panB 7768080 panB Clostridium botulinum A2 str. Kyoto 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_002802752.1 545876 R 536232 CDS YP_002802753.1 226947662 7764963 547479..550922 1 NC_012563.1 identified by match to protein family HMM TIGR02773; ATP-dependent nuclease subunit B 550922 addB 7764963 addB Clostridium botulinum A2 str. Kyoto ATP-dependent nuclease subunit B YP_002802753.1 547479 D 536232 CDS YP_002802754.1 226947663 7765796 complement(551047..551538) 1 NC_012563.1 hypothetical protein 551538 7765796 CLM_0507 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802754.1 551047 R 536232 CDS YP_002802755.1 226947664 7766607 551849..552499 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein 552499 7766607 CLM_0508 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802755.1 551849 D 536232 CDS YP_002802756.1 226947665 7767116 552502..553188 1 NC_012563.1 hypothetical protein 553188 7767116 CLM_0509 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802756.1 552502 D 536232 CDS YP_002802757.1 226947666 7766244 complement(553435..554043) 1 NC_012563.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 554043 7766244 CLM_0510 Clostridium botulinum A2 str. Kyoto TetR family transcriptional regulator YP_002802757.1 553435 R 536232 CDS YP_002802758.1 226947667 7765320 554290..554961 1 NC_012563.1 identified by match to protein family HMM PF02492; match to protein family HMM TIGR00073; hydrogenase accessory protein HypB 554961 hypB 7765320 hypB Clostridium botulinum A2 str. Kyoto hydrogenase accessory protein HypB YP_002802758.1 554290 D 536232 CDS YP_002802759.1 226947668 7764343 555197..557875 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00070; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase family protein 557875 7764343 CLM_0512 Clostridium botulinum A2 str. Kyoto pyridine nucleotide-disulfide oxidoreductase family protein YP_002802759.1 555197 D 536232 CDS YP_002802760.1 226947669 7767883 557931..558272 1 NC_012563.1 identified by match to protein family HMM PF01155; hydrogenase nickel insertion protein HypA 558272 hypA 7767883 hypA Clostridium botulinum A2 str. Kyoto hydrogenase nickel insertion protein HypA YP_002802760.1 557931 D 536232 CDS YP_002802761.1 226947670 7766747 558310..559296 1 NC_012563.1 hypothetical protein 559296 7766747 CLM_0514 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802761.1 558310 D 536232 CDS YP_002802762.1 226947671 7766594 complement(559581..560069) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 560069 7766594 CLM_0515 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802762.1 559581 R 536232 CDS YP_002802763.1 226947672 7764291 561377..565216 1 NC_012563.1 identified by similarity to SP:P23478; match to protein family HMM PF00580; match to protein family HMM TIGR02785; ATP-dependent nuclease subunit A 565216 addA 7764291 addA Clostridium botulinum A2 str. Kyoto ATP-dependent nuclease subunit A YP_002802763.1 561377 D 536232 CDS YP_002802764.1 226947673 7767805 565356..567047 1 NC_012563.1 identified by match to protein family HMM PF00015; methyl-accepting chemotaxis protein 567047 7767805 CLM_0519 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002802764.1 565356 D 536232 CDS YP_002802765.1 226947674 7766888 567124..568350 1 NC_012563.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 568350 pepT 7766888 pepT Clostridium botulinum A2 str. Kyoto peptidase T YP_002802765.1 567124 D 536232 CDS YP_002802766.1 226947675 7765631 complement(568625..569557) 1 NC_012563.1 identified by match to protein family HMM PF01734; phospholipase family protein 569557 7765631 CLM_0521 Clostridium botulinum A2 str. Kyoto phospholipase family protein YP_002802766.1 568625 R 536232 CDS YP_002802767.1 226947676 7764559 570201..570851 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; metallo-beta-lactamase family protein 570851 7764559 CLM_0522 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002802767.1 570201 D 536232 CDS YP_002802768.1 226947677 7765441 571057..571515 1 NC_012563.1 identified by match to protein family HMM PF00903; glyoxalase 571515 7765441 CLM_0523 Clostridium botulinum A2 str. Kyoto glyoxalase YP_002802768.1 571057 D 536232 CDS YP_002802769.1 226947678 7764296 571565..571963 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 571963 7764296 CLM_0524 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002802769.1 571565 D 536232 CDS YP_002802770.1 226947679 7765107 572068..572289 1 NC_012563.1 hypothetical protein 572289 7765107 CLM_0525 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802770.1 572068 D 536232 CDS YP_002802771.1 226947680 7767675 572502..573917 1 NC_012563.1 identified by match to protein family HMM PF04122; N-acetylmuramoyl-L-alanine amidase-like protein 573917 7767675 CLM_0526 Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase-like protein YP_002802771.1 572502 D 536232 CDS YP_002802772.1 226947681 7767031 complement(574181..574816) 1 NC_012563.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 574816 7767031 CLM_0527 Clostridium botulinum A2 str. Kyoto amino acid ABC transporter permease YP_002802772.1 574181 R 536232 CDS YP_002802773.1 226947682 7765351 complement(574829..575632) 1 NC_012563.1 identified by match to protein family HMM PF00497; polar amino acid uptake ABC transporter amino acid-binding protein 575632 7765351 CLM_0528 Clostridium botulinum A2 str. Kyoto polar amino acid uptake ABC transporter amino acid-binding protein YP_002802773.1 574829 R 536232 CDS YP_002802774.1 226947683 7765471 575854..576582 1 NC_012563.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; hypothetical protein 576582 7765471 CLM_0529 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802774.1 575854 D 536232 CDS YP_002802775.1 226947684 7764610 complement(576931..578142) 1 NC_012563.1 identified by match to protein family HMM PF00563; match to protein family HMM PF08668; EAL domain-containing protein 578142 7764610 CLM_0530 Clostridium botulinum A2 str. Kyoto EAL domain-containing protein YP_002802775.1 576931 R 536232 CDS YP_002802776.1 226947685 7767215 complement(578407..579024) 1 NC_012563.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 579024 thiE 7767215 thiE Clostridium botulinum A2 str. Kyoto thiamine-phosphate pyrophosphorylase YP_002802776.1 578407 R 536232 CDS YP_002802777.1 226947686 7766374 complement(579015..579806) 1 NC_012563.1 identified by match to protein family HMM PF02110; match to protein family HMM TIGR00694; hydroxyethylthiazole kinase 579806 thiM 7766374 thiM Clostridium botulinum A2 str. Kyoto hydroxyethylthiazole kinase YP_002802777.1 579015 R 536232 CDS YP_002802778.1 226947687 7768123 complement(580037..580837) 1 NC_012563.1 identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097; phosphomethylpyrimidine kinase 580837 thiD 7768123 thiD Clostridium botulinum A2 str. Kyoto phosphomethylpyrimidine kinase YP_002802778.1 580037 R 536232 CDS YP_002802779.1 226947688 7766899 581862..582764 1 NC_012563.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 582764 ddl 7766899 ddl Clostridium botulinum A2 str. Kyoto D-alanine--D-alanine ligase YP_002802779.1 581862 D 536232 CDS YP_002802780.1 226947689 7767304 582920..584062 1 NC_012563.1 identified by match to protein family HMM PF01094; putative high-affinity branched-chain amino acid ABC transporter amino acid-binding protein 584062 7767304 CLM_0536 Clostridium botulinum A2 str. Kyoto putative high-affinity branched-chain amino acid ABC transporter amino acid-binding protein YP_002802780.1 582920 D 536232 CDS YP_002802781.1 226947690 7765169 584066..584938 1 NC_012563.1 identified by match to protein family HMM PF02653; high-affinity branched-chain amino acid ABC transporter permease 584938 7765169 CLM_0537 Clostridium botulinum A2 str. Kyoto high-affinity branched-chain amino acid ABC transporter permease YP_002802781.1 584066 D 536232 CDS YP_002802782.1 226947691 7765554 584939..585883 1 NC_012563.1 identified by match to protein family HMM PF02653; putative high-affinity branched-chain amino acid ABC transporter permease 585883 7765554 CLM_0538 Clostridium botulinum A2 str. Kyoto putative high-affinity branched-chain amino acid ABC transporter permease YP_002802782.1 584939 D 536232 CDS YP_002802783.1 226947692 7766154 585895..586632 1 NC_012563.1 identified by match to protein family HMM PF00005; putative high-affinity branched chain amino acid ABC transporter ATP-binding protein 586632 7766154 CLM_0539 Clostridium botulinum A2 str. Kyoto putative high-affinity branched chain amino acid ABC transporter ATP-binding protein YP_002802783.1 585895 D 536232 CDS YP_002802784.1 226947693 7765755 586634..587335 1 NC_012563.1 identified by match to protein family HMM PF00005; putative high-affinity branched chain amino acid ABC transporter ATP-binding protein 587335 7765755 CLM_0540 Clostridium botulinum A2 str. Kyoto putative high-affinity branched chain amino acid ABC transporter ATP-binding protein YP_002802784.1 586634 D 536232 CDS YP_002802785.1 226947694 7766446 587364..588140 1 NC_012563.1 identified by match to protein family HMM PF02596; hypothetical protein 588140 7766446 CLM_0541 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802785.1 587364 D 536232 CDS YP_002802786.1 226947695 7767976 588542..589300 1 NC_012563.1 identified by match to protein family HMM PF06738; hypothetical protein 589300 7767976 CLM_0542 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802786.1 588542 D 536232 CDS YP_002802787.1 226947696 7764904 589294..589737 1 NC_012563.1 hypothetical protein 589737 7764904 CLM_0543 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802787.1 589294 D 536232 CDS YP_002802788.1 226947697 7765137 589879..591330 1 NC_012563.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 591330 7765137 CLM_0544 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002802788.1 589879 D 536232 CDS YP_002802789.1 226947698 7766045 591391..591960 1 NC_012563.1 identified by match to protein family HMM PF04011; lemA family protein 591960 7766045 CLM_0545 Clostridium botulinum A2 str. Kyoto lemA family protein YP_002802789.1 591391 D 536232 CDS YP_002802790.1 226947699 7767515 591970..592806 1 NC_012563.1 identified by match to protein family HMM PF04536; putative lipoprotein 592806 7767515 CLM_0546 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002802790.1 591970 D 536232 CDS YP_002802791.1 226947700 7766633 593324..594184 1 NC_012563.1 identified by match to protein family HMM PF04536; hypothetical protein 594184 7766633 CLM_0547 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802791.1 593324 D 536232 CDS YP_002802792.1 226947701 7765740 594458..595351 1 NC_012563.1 identified by match to protein family HMM PF00293; NUDIX family hydrolase 595351 7765740 CLM_0548 Clostridium botulinum A2 str. Kyoto NUDIX family hydrolase YP_002802792.1 594458 D 536232 CDS YP_002802793.1 226947702 7764874 595485..595967 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 595967 7764874 CLM_0549 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802793.1 595485 D 536232 CDS YP_002802794.1 226947703 7765214 596143..596667 1 NC_012563.1 hypothetical protein 596667 7765214 CLM_0550 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802794.1 596143 D 536232 CDS YP_002802795.1 226947704 7766356 596669..597259 1 NC_012563.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242; methlytransferase 597259 7766356 CLM_0551 Clostridium botulinum A2 str. Kyoto methlytransferase YP_002802795.1 596669 D 536232 CDS YP_002802796.1 226947705 7764958 complement(597345..597584) 1 NC_012563.1 hypothetical protein 597584 7764958 CLM_0552 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802796.1 597345 R 536232 CDS YP_002802797.1 226947706 7766090 complement(597605..597799) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 597799 7766090 CLM_0553 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802797.1 597605 R 536232 CDS YP_002802798.1 226947707 7764538 598300..598434 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 598434 7764538 CLM_0554 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802798.1 598300 D 536232 CDS YP_002802799.1 226947708 7767340 598681..599910 1 NC_012563.1 identified by similarity to SP:P13457; match to protein family HMM PF00149; match to protein family HMM TIGR00619; exonuclease SbcCD subunit D 599910 sbcD 7767340 sbcD Clostridium botulinum A2 str. Kyoto exonuclease SbcCD subunit D YP_002802799.1 598681 D 536232 CDS YP_002802800.1 226947709 7767440 599885..603415 1 NC_012563.1 identified by similarity to SP:P13458; match to protein family HMM PF02463; exonuclease SbcCD subunit C 603415 sbcC 7767440 sbcC Clostridium botulinum A2 str. Kyoto exonuclease SbcCD subunit C YP_002802800.1 599885 D 536232 CDS YP_002802801.1 226947710 7766573 603443..603991 1 NC_012563.1 identified by match to protein family HMM PF00293; NUDIX family hydrolase 603991 7766573 CLM_0557 Clostridium botulinum A2 str. Kyoto NUDIX family hydrolase YP_002802801.1 603443 D 536232 CDS YP_002802802.1 226947711 7766852 604820..605671 1 NC_012563.1 identified by match to protein family HMM PF02588; hypothetical protein 605671 7766852 CLM_0558 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802802.1 604820 D 536232 CDS YP_002802803.1 226947712 7765977 complement(605766..605927) 1 NC_012563.1 identified by match to protein family HMM PF07561; hypothetical protein 605927 7765977 CLM_0559 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802803.1 605766 R 536232 CDS YP_002802804.1 226947713 7768025 606140..606505 1 NC_012563.1 identified by match to protein family HMM PF01022; putative cadmium resistance transcriptional regulator CadC 606505 7768025 CLM_0560 Clostridium botulinum A2 str. Kyoto putative cadmium resistance transcriptional regulator CadC YP_002802804.1 606140 D 536232 CDS YP_002802805.1 226947714 7767153 606581..608797 1 NC_012563.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525; cadmium-exporting ATPase 608797 cadA 7767153 cadA Clostridium botulinum A2 str. Kyoto cadmium-exporting ATPase YP_002802805.1 606581 D 536232 CDS YP_002802806.1 226947715 7768216 610017..610838 1 NC_012563.1 identified by match to protein family HMM PF00877; match to protein family HMM PF01471; NlpC/P60 family protein 610838 7768216 CLM_0563 Clostridium botulinum A2 str. Kyoto NlpC/P60 family protein YP_002802806.1 610017 D 536232 CDS YP_002802807.1 226947716 7764507 610971..611114 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; recombinase, phage RecT family 611114 7764507 CLM_0564 Clostridium botulinum A2 str. Kyoto recombinase, phage RecT family YP_002802807.1 610971 D 536232 CDS YP_002802808.1 226947717 7765666 611153..611353 1 NC_012563.1 hypothetical protein 611353 7765666 CLM_0565 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802808.1 611153 D 536232 CDS YP_002802809.1 226947718 7764812 611881..612228 1 NC_012563.1 hypothetical protein 612228 7764812 CLM_0566 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802809.1 611881 D 536232 CDS YP_002802810.1 226947719 7765904 complement(612247..612396) 1 NC_012563.1 hypothetical protein 612396 7765904 CLM_0567 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802810.1 612247 R 536232 CDS YP_002802811.1 226947720 7766479 612907..613716 1 NC_012563.1 hypothetical protein 613716 7766479 CLM_0568 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802811.1 612907 D 536232 CDS YP_002802812.1 226947721 7765061 614355..615731 1 NC_012563.1 identified by match to protein family HMM PF02562; PhoH family protein 615731 7765061 CLM_0569 Clostridium botulinum A2 str. Kyoto PhoH family protein YP_002802812.1 614355 D 536232 CDS YP_002802813.1 226947722 7767756 615999..617003 1 NC_012563.1 hypothetical protein 617003 7767756 CLM_0570 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802813.1 615999 D 536232 CDS YP_002802814.1 226947723 7766818 617013..618029 1 NC_012563.1 hypothetical protein 618029 7766818 CLM_0571 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802814.1 617013 D 536232 CDS YP_002802815.1 226947724 7765336 618349..618522 1 NC_012563.1 bacteriocin protoxin, streptolysin S family 618522 7765336 CLM_0572 Clostridium botulinum A2 str. Kyoto bacteriocin protoxin, streptolysin S family YP_002802815.1 618349 D 536232 CDS YP_002802816.1 226947725 7764499 618687..619643 1 NC_012563.1 identified by similarity to GB:AAN16972.1; match to protein family HMM TIGR03605; streptolysin associated protein SagB 619643 sagB 7764499 sagB Clostridium botulinum A2 str. Kyoto streptolysin associated protein SagB YP_002802816.1 618687 D 536232 CDS YP_002802817.1 226947726 7767134 619647..620729 1 NC_012563.1 identified by match to protein family HMM TIGR03603; bacteriocin biosynthesis cyclodehydratase 620729 7767134 CLM_0574 Clostridium botulinum A2 str. Kyoto bacteriocin biosynthesis cyclodehydratase YP_002802817.1 619647 D 536232 CDS YP_002802818.1 226947727 7766271 620745..622103 1 NC_012563.1 identified by match to protein family HMM PF02624; match to protein family HMM TIGR03604; streptolysin associated protein SagD 622103 sagD 7766271 sagD Clostridium botulinum A2 str. Kyoto streptolysin associated protein SagD YP_002802818.1 620745 D 536232 CDS YP_002802819.1 226947728 7764893 622078..622716 1 NC_012563.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family protein 622716 7764893 CLM_0576 Clostridium botulinum A2 str. Kyoto CAAX amino terminal protease family protein YP_002802819.1 622078 D 536232 CDS YP_002802820.1 226947729 7767995 622724..623452 1 NC_012563.1 hypothetical protein 623452 7767995 CLM_0577 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802820.1 622724 D 536232 CDS YP_002802821.1 226947730 7766810 623761..624693 1 NC_012563.1 identified by similarity to GB:AAN16977.1; match to protein family HMM PF00005; ABC transporter ATP-binding protein 624693 sagG 7766810 sagG Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002802821.1 623761 D 536232 CDS YP_002802822.1 226947731 7767659 624705..625829 1 NC_012563.1 identified by match to protein family HMM PF01061; ABC transporter ATP-binding protein/permease 625829 sagH 7767659 sagH Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein/permease YP_002802822.1 624705 D 536232 CDS YP_002802823.1 226947732 7764995 625831..626973 1 NC_012563.1 identified by match to protein family HMM PF01061; drug ABC transporter, ATP-binding/permease 626973 sagI 7764995 sagI Clostridium botulinum A2 str. Kyoto drug ABC transporter, ATP-binding/permease YP_002802823.1 625831 D 536232 CDS YP_002802824.1 226947733 7765889 627217..627867 1 NC_012563.1 identified by match to protein family HMM PF02163; putative metalloprotease 627867 7765889 CLM_0582 Clostridium botulinum A2 str. Kyoto putative metalloprotease YP_002802824.1 627217 D 536232 CDS YP_002802825.1 226947734 7765930 628120..629211 1 NC_012563.1 identified by match to protein family HMM PF07730; sensor histidine kinase 629211 7765930 CLM_0583 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002802825.1 628120 D 536232 CDS YP_002802826.1 226947735 7767046 629377..630009 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family DNA-binding response regulator 630009 7767046 CLM_0584 Clostridium botulinum A2 str. Kyoto LuxR family DNA-binding response regulator YP_002802826.1 629377 D 536232 CDS YP_002802827.1 226947736 7764268 630431..631366 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 631366 7764268 CLM_0585 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002802827.1 630431 D 536232 CDS YP_002802828.1 226947737 7765323 631378..632496 1 NC_012563.1 identified by match to protein family HMM PF01061; multidrug ABC transporter permease 632496 7765323 CLM_0586 Clostridium botulinum A2 str. Kyoto multidrug ABC transporter permease YP_002802828.1 631378 D 536232 CDS YP_002802829.1 226947738 7765650 632496..633644 1 NC_012563.1 identified by match to protein family HMM PF01061; multidrug ABC transporter permease 633644 7765650 CLM_0587 Clostridium botulinum A2 str. Kyoto multidrug ABC transporter permease YP_002802829.1 632496 D 536232 CDS YP_002802830.1 226947739 7766178 complement(633763..634233) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 634233 7766178 CLM_0588 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802830.1 633763 R 536232 CDS YP_002802831.1 226947740 7764822 complement(634351..635613) 1 NC_012563.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600; arsenical pump family protein 635613 7764822 CLM_0589 Clostridium botulinum A2 str. Kyoto arsenical pump family protein YP_002802831.1 634351 R 536232 CDS YP_002802832.1 226947741 7765395 complement(635740..637104) 1 NC_012563.1 hypothetical protein 637104 7765395 CLM_0590 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802832.1 635740 R 536232 CDS YP_002802833.1 226947742 7766579 637380..638033 1 NC_012563.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 638033 trmB 7766579 trmB Clostridium botulinum A2 str. Kyoto tRNA (guanine-N(7)-)-methyltransferase YP_002802833.1 637380 D 536232 CDS YP_002802834.1 226947743 7766279 638246..638509 1 NC_012563.1 hypothetical protein 638509 7766279 CLM_0592 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802834.1 638246 D 536232 CDS YP_002802835.1 226947744 7767375 complement(638604..639098) 1 NC_012563.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 639098 tpx 7767375 tpx Clostridium botulinum A2 str. Kyoto thiol peroxidase YP_002802835.1 638604 R 536232 CDS YP_002802836.1 226947745 7765935 639480..640223 1 NC_012563.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 640223 fabG 7765935 fabG Clostridium botulinum A2 str. Kyoto 3-ketoacyl-ACP reductase YP_002802836.1 639480 D 536232 CDS YP_002802837.1 226947746 7767142 640286..641239 1 NC_012563.1 identified by match to protein family HMM PF00072; response regulator 641239 7767142 CLM_0595 Clostridium botulinum A2 str. Kyoto response regulator YP_002802837.1 640286 D 536232 CDS YP_002802838.1 226947747 7765979 complement(641363..643687) 1 NC_012563.1 identified by match to protein family HMM PF00877; match to protein family HMM PF05257; match to protein family HMM PF06347; match to protein family HMM PF08239; NlpC/P60 family protein 643687 7765979 CLM_0596 Clostridium botulinum A2 str. Kyoto NlpC/P60 family protein YP_002802838.1 641363 R 536232 CDS YP_002802839.1 226947748 7765161 643996..644940 1 NC_012563.1 identified by match to protein family HMM PF00561; hydrolase, alpha/beta fold family 644940 7765161 CLM_0597 Clostridium botulinum A2 str. Kyoto hydrolase, alpha/beta fold family YP_002802839.1 643996 D 536232 CDS YP_002802840.1 226947749 7766602 645202..646449 1 NC_012563.1 identified by match to protein family HMM PF00072; response regulator 646449 7766602 CLM_0598 Clostridium botulinum A2 str. Kyoto response regulator YP_002802840.1 645202 D 536232 CDS YP_002802841.1 226947750 7765031 646746..647330 1 NC_012563.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; HDIG domain-containing protein 647330 7765031 CLM_0599 Clostridium botulinum A2 str. Kyoto HDIG domain-containing protein YP_002802841.1 646746 D 536232 CDS YP_002802842.1 226947751 7765419 647366..649396 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis protein 649396 7765419 CLM_0600 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002802842.1 647366 D 536232 CDS YP_002802843.1 226947752 7766549 649601..650395 1 NC_012563.1 identified by match to protein family HMM PF00072; response regulator 650395 7766549 CLM_0601 Clostridium botulinum A2 str. Kyoto response regulator YP_002802843.1 649601 D 536232 CDS YP_002802844.1 226947753 7766760 650877..652154 1 NC_012563.1 identified by match to protein family HMM PF00587; match to protein family HMM PF02403; match to protein family HMM TIGR00414; serine--tRNA ligase 652154 serS 7766760 serS Clostridium botulinum A2 str. Kyoto serine--tRNA ligase YP_002802844.1 650877 D 536232 CDS YP_002802845.1 226947754 7767828 652749..655103 1 NC_012563.1 identified by match to protein family HMM PF06733; putative ATP-dependent helicase 655103 7767828 CLM_0603 Clostridium botulinum A2 str. Kyoto putative ATP-dependent helicase YP_002802845.1 652749 D 536232 CDS YP_002802846.1 226947755 7764756 complement(655388..655579) 1 NC_012563.1 hypothetical protein 655579 7764756 CLM_0604 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802846.1 655388 R 536232 CDS YP_002802847.1 226947756 7765949 complement(656072..656692) 1 NC_012563.1 identified by match to protein family HMM PF00392; match to protein family HMM PF02080; GntR family transcriptional regulator 656692 7765949 CLM_0605 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002802847.1 656072 R 536232 CDS YP_002802848.1 226947757 7765048 656947..657900 1 NC_012563.1 identified by match to protein family HMM PF01262; N(5)-(carboxyethyl)ornithine synthase 657900 ceo 7765048 ceo Clostridium botulinum A2 str. Kyoto N(5)-(carboxyethyl)ornithine synthase YP_002802848.1 656947 D 536232 CDS YP_002802849.1 226947758 7765940 complement(658104..660110) 1 NC_012563.1 identified by match to protein family HMM PF06874; fructose-1,6-bisphosphatase 660110 7765940 CLM_0607 Clostridium botulinum A2 str. Kyoto fructose-1,6-bisphosphatase YP_002802849.1 658104 R 536232 CDS YP_002802850.1 226947759 7766350 660394..660756 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 660756 7766350 CLM_0608 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802850.1 660394 D 536232 CDS YP_002802851.1 226947760 7765324 660957..661370 1 NC_012563.1 identified by match to protein family HMM PF01814; match to protein family HMM TIGR02481; hemerythrin-like metal-binding domain-containing protein 661370 7765324 CLM_0609 Clostridium botulinum A2 str. Kyoto hemerythrin-like metal-binding domain-containing protein YP_002802851.1 660957 D 536232 CDS YP_002802852.1 226947761 7767110 complement(661582..662277) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 662277 7767110 CLM_0610 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802852.1 661582 R 536232 CDS YP_002802853.1 226947762 7767759 663029..663451 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 663451 7767759 CLM_0611 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802853.1 663029 D 536232 CDS YP_002802854.1 226947763 7764280 complement(663684..664334) 1 NC_012563.1 identified by match to protein family HMM PF02777; superoxide dismutase, Mn/Fe family 664334 7764280 CLM_0612 Clostridium botulinum A2 str. Kyoto superoxide dismutase, Mn/Fe family YP_002802854.1 663684 R 536232 CDS YP_002802855.1 226947764 7765304 664527..665366 1 NC_012563.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 665366 7765304 CLM_0613 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002802855.1 664527 D 536232 CDS YP_002802856.1 226947765 7766964 666023..667264 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 667264 7766964 CLM_0614 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002802856.1 666023 D 536232 CDS YP_002802857.1 226947766 7768058 667302..668339 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 668339 7768058 CLM_0615 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002802857.1 667302 D 536232 CDS YP_002802858.1 226947767 7768085 668546..668722 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 668722 7768085 CLM_0616 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802858.1 668546 D 536232 CDS YP_002802859.1 226947768 7765355 668752..668925 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 668925 7765355 CLM_0617 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802859.1 668752 D 536232 CDS YP_002802860.1 226947769 7766249 669123..670118 1 NC_012563.1 putative serine protease 670118 7766249 CLM_0618 Clostridium botulinum A2 str. Kyoto putative serine protease YP_002802860.1 669123 D 536232 CDS YP_002802861.1 226947770 7767920 670105..671814 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; lipid A export ATP-binding/permease MsbA 671814 7767920 CLM_0619 Clostridium botulinum A2 str. Kyoto lipid A export ATP-binding/permease MsbA YP_002802861.1 670105 D 536232 CDS YP_002802862.1 226947771 7767054 671859..672545 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; regulatory protein VanR 672545 7767054 CLM_0620 Clostridium botulinum A2 str. Kyoto regulatory protein VanR YP_002802862.1 671859 D 536232 CDS YP_002802863.1 226947772 7765702 672542..673573 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; two-component sensor histidine kinase 673573 7765702 CLM_0621 Clostridium botulinum A2 str. Kyoto two-component sensor histidine kinase YP_002802863.1 672542 D 536232 CDS YP_002802864.1 226947773 7765782 673759..674424 1 NC_012563.1 identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease MacB 674424 7765782 CLM_0622 Clostridium botulinum A2 str. Kyoto macrolide export ATP-binding/permease MacB YP_002802864.1 673759 D 536232 CDS YP_002802865.1 226947774 7764702 674438..676948 1 NC_012563.1 identified by match to protein family HMM PF02687; efflux ABC transporter permease 676948 7764702 CLM_0623 Clostridium botulinum A2 str. Kyoto efflux ABC transporter permease YP_002802865.1 674438 D 536232 CDS YP_002802866.1 226947775 7768074 complement(677997..678296) 1 NC_012563.1 hypothetical protein 678296 7768074 CLM_0624 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802866.1 677997 R 536232 CDS YP_002802867.1 226947776 7767347 complement(678444..680297) 1 NC_012563.1 hypothetical protein 680297 7767347 CLM_0625 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802867.1 678444 R 536232 CDS YP_002802868.1 226947777 7765633 680570..680689 1 NC_012563.1 hypothetical protein 680689 7765633 CLM_0626 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802868.1 680570 D 536232 CDS YP_002802869.1 226947778 7764386 complement(680977..681441) 1 NC_012563.1 identified by match to protein family HMM PF01037; AsnC family transcriptional regulator 681441 7764386 CLM_0627 Clostridium botulinum A2 str. Kyoto AsnC family transcriptional regulator YP_002802869.1 680977 R 536232 CDS YP_002802870.1 226947779 7767885 681966..682340 1 NC_012563.1 hypothetical protein 682340 7767885 CLM_0628 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802870.1 681966 D 536232 CDS YP_002802871.1 226947780 7766816 682964..684337 1 NC_012563.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03845; amino acid permease family protein 684337 7766816 CLM_0629 Clostridium botulinum A2 str. Kyoto amino acid permease family protein YP_002802871.1 682964 D 536232 CDS YP_002802872.1 226947781 7766187 684775..686124 1 NC_012563.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03845; amino acid permease family protein 686124 7766187 CLM_0630 Clostridium botulinum A2 str. Kyoto amino acid permease family protein YP_002802872.1 684775 D 536232 CDS YP_002802873.1 226947782 7767569 686472..686981 1 NC_012563.1 identified by match to protein family HMM PF00132; transferase hexapeptide domain-containing protein 686981 7767569 CLM_0631 Clostridium botulinum A2 str. Kyoto transferase hexapeptide domain-containing protein YP_002802873.1 686472 D 536232 CDS YP_002802874.1 226947783 7764760 687026..687898 1 NC_012563.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 687898 7764760 CLM_0632 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002802874.1 687026 D 536232 CDS YP_002802875.1 226947784 7765884 complement(688167..690785) 1 NC_012563.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01517; calcium-translocating P-type ATPase 690785 7765884 CLM_0633 Clostridium botulinum A2 str. Kyoto calcium-translocating P-type ATPase YP_002802875.1 688167 R 536232 CDS YP_002802876.1 226947785 7766957 complement(691079..691615) 1 NC_012563.1 identified by match to protein family HMM PF02417; chromate transporter protein 691615 7766957 CLM_0635 Clostridium botulinum A2 str. Kyoto chromate transporter protein YP_002802876.1 691079 R 536232 CDS YP_002802877.1 226947786 7768035 complement(691615..692151) 1 NC_012563.1 identified by match to protein family HMM PF02417; chromate transport protein 692151 7768035 CLM_0636 Clostridium botulinum A2 str. Kyoto chromate transport protein YP_002802877.1 691615 R 536232 CDS YP_002802878.1 226947787 7765617 692325..692915 1 NC_012563.1 identified by match to protein family HMM PF02452; PemK family protein 692915 7765617 CLM_0637 Clostridium botulinum A2 str. Kyoto PemK family protein YP_002802878.1 692325 D 536232 CDS YP_002802879.1 226947788 7766590 693362..693787 1 NC_012563.1 identified by match to protein family HMM PF03885; hypothetical protein 693787 7766590 CLM_0638 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802879.1 693362 D 536232 CDS YP_002802880.1 226947789 7764780 complement(693993..695909) 1 NC_012563.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 695909 nadE 7764780 nadE Clostridium botulinum A2 str. Kyoto NAD synthetase YP_002802880.1 693993 R 536232 CDS YP_002802881.1 226947790 7764845 696131..696571 1 NC_012563.1 identified by match to protein family HMM PF01957; hypothetical protein 696571 7764845 CLM_0640 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802881.1 696131 D 536232 CDS YP_002802882.1 226947791 7766420 696574..697512 1 NC_012563.1 identified by match to protein family HMM PF01145; SPFH domain/Band 7 family protein 697512 7766420 CLM_0641 Clostridium botulinum A2 str. Kyoto SPFH domain/Band 7 family protein YP_002802882.1 696574 D 536232 CDS YP_002802883.1 226947792 7765555 697558..697698 1 NC_012563.1 hypothetical protein 697698 7765555 CLM_0642 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802883.1 697558 D 536232 CDS YP_002802884.1 226947793 7765281 698169..699404 1 NC_012563.1 identified by match to protein family HMM PF00557; match to protein family HMM PF05195; Xaa-pro aminopeptidase 699404 pepP 7765281 pepP Clostridium botulinum A2 str. Kyoto Xaa-pro aminopeptidase YP_002802884.1 698169 D 536232 CDS YP_002802885.1 226947794 7764393 complement(700057..700506) 1 NC_012563.1 hypothetical protein 700506 7764393 CLM_0644 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802885.1 700057 R 536232 CDS YP_002802886.1 226947795 7767953 complement(700924..701127) 1 NC_012563.1 identified by match to protein family HMM PF01381; hypothetical protein 701127 7767953 CLM_0645 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802886.1 700924 R 536232 CDS YP_002802887.1 226947796 7767080 complement(701276..701725) 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 701725 7767080 CLM_0646 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002802887.1 701276 R 536232 CDS YP_002802888.1 226947797 7767483 702120..702332 1 NC_012563.1 identified by match to protein family HMM PF04324; [2Fe-2S]-binding domain-containing protein 702332 7767483 CLM_0647 Clostridium botulinum A2 str. Kyoto [2Fe-2S]-binding domain-containing protein YP_002802888.1 702120 D 536232 CDS YP_002802889.1 226947798 7766626 702804..702941 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 702941 7766626 CLM_0648 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802889.1 702804 D 536232 CDS YP_002802890.1 226947799 7765268 703123..703197 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 703197 7765268 CLM_0649 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802890.1 703123 D 536232 CDS YP_002802891.1 226947800 7767951 703296..704204 1 NC_012563.1 hypothetical protein 704204 7767951 CLM_0650 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802891.1 703296 D 536232 CDS YP_002802892.1 226947801 7764566 704472..704981 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 704981 7764566 CLM_0651 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802892.1 704472 D 536232 CDS YP_002802893.1 226947802 7765467 704993..706636 1 NC_012563.1 identified by match to protein family HMM PF02554; carbon starvation protein CstA 706636 7765467 CLM_0652 Clostridium botulinum A2 str. Kyoto carbon starvation protein CstA YP_002802893.1 704993 D 536232 CDS YP_002802894.1 226947803 7766342 707218..707907 1 NC_012563.1 hypothetical protein 707907 7766342 CLM_0653 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802894.1 707218 D 536232 CDS YP_002802895.1 226947804 7765954 708827..710818 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 710818 7765954 CLM_0654 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002802895.1 708827 D 536232 CDS YP_002802896.1 226947805 7766331 complement(711322..712980) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 712980 7766331 CLM_0655 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002802896.1 711322 R 536232 CDS YP_002802897.1 226947806 7767425 713456..713857 1 NC_012563.1 identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220; large conductance mechanosensitive channel protein 713857 mscL 7767425 mscL Clostridium botulinum A2 str. Kyoto large conductance mechanosensitive channel protein YP_002802897.1 713456 D 536232 CDS YP_002802898.1 226947807 7764602 714096..714779 1 NC_012563.1 identified by match to protein family HMM PF09515; match to protein family HMM TIGR02357; putative proton-coupled thiamine transporter YuaJ 714779 7764602 CLM_0658 Clostridium botulinum A2 str. Kyoto putative proton-coupled thiamine transporter YuaJ YP_002802898.1 714096 D 536232 CDS YP_002802899.1 226947808 7766777 complement(714912..715049) 1 NC_012563.1 hypothetical protein 715049 7766777 CLM_0659 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802899.1 714912 R 536232 CDS YP_002802900.1 226947809 7767902 715697..716848 1 NC_012563.1 identified by match to protein family HMM PF02810; SEC-C motif domain-containing protein 716848 7767902 CLM_0660 Clostridium botulinum A2 str. Kyoto SEC-C motif domain-containing protein YP_002802900.1 715697 D 536232 CDS YP_002802901.1 226947810 7764925 717150..717530 1 NC_012563.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 717530 7764925 CLM_0661 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002802901.1 717150 D 536232 CDS YP_002802902.1 226947811 7764426 717523..718218 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 718218 7764426 CLM_0662 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002802902.1 717523 D 536232 CDS YP_002802903.1 226947812 7766820 718218..718979 1 NC_012563.1 putative ABC transporter permease 718979 7766820 CLM_0663 Clostridium botulinum A2 str. Kyoto putative ABC transporter permease YP_002802903.1 718218 D 536232 CDS YP_002802904.1 226947813 7766926 721243..722325 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402; match to protein family HMM TIGR01187; spermidine/putrescine ABC transporter ATP-binding protein 722325 potA 7766926 potA Clostridium botulinum A2 str. Kyoto spermidine/putrescine ABC transporter ATP-binding protein YP_002802904.1 721243 D 536232 CDS YP_002802905.1 226947814 7764227 722325..723284 1 NC_012563.1 identified by similarity to SP:P0AFK4; match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 723284 potB 7764227 potB Clostridium botulinum A2 str. Kyoto spermidine/putrescine ABC transporter permease YP_002802905.1 722325 D 536232 CDS YP_002802906.1 226947815 7767306 723284..725128 1 NC_012563.1 identified by similarity to SP:P0AFK6; similarity to SP:P0AFK9; match to protein family HMM PF00528; match to protein family HMM PF01547; spermidine/putrescine transport system permease PotC/spermidine/putrescine-binding periplasmic protein PotD 725128 potCD 7767306 potCD Clostridium botulinum A2 str. Kyoto spermidine/putrescine transport system permease PotC/spermidine/putrescine-binding periplasmic protein PotD YP_002802906.1 723284 D 536232 CDS YP_002802907.1 226947816 7766464 complement(725337..726206) 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 726206 7766464 CLM_0668 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002802907.1 725337 R 536232 CDS YP_002802908.1 226947817 7765550 726320..726463 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 726463 7765550 CLM_0669 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802908.1 726320 D 536232 CDS YP_002802909.1 226947818 7767703 726645..727898 1 NC_012563.1 identified by similarity to SP:P24943; match to protein family HMM PF00375; proton/sodium-glutamate symporter 727898 7767703 CLM_0670 Clostridium botulinum A2 str. Kyoto proton/sodium-glutamate symporter YP_002802909.1 726645 D 536232 CDS YP_002802910.1 226947819 7767677 728491..729051 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 729051 7767677 CLM_0671 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802910.1 728491 D 536232 CDS YP_002802911.1 226947820 7764378 729287..729616 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 729616 7764378 CLM_0672 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802911.1 729287 D 536232 CDS YP_002802912.1 226947821 7765373 729699..730253 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 730253 7765373 CLM_0673 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802912.1 729699 D 536232 CDS YP_002802913.1 226947822 7767042 complement(730318..732405) 1 NC_012563.1 identified by match to protein family HMM PF01471; match to protein family HMM PF08924; YbfG 732405 7767042 CLM_0674 Clostridium botulinum A2 str. Kyoto YbfG YP_002802913.1 730318 R 536232 CDS YP_002802914.1 226947823 7764216 732747..732929 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 732929 7764216 CLM_0675 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802914.1 732747 D 536232 CDS YP_002802915.1 226947824 7764898 733343..733546 1 NC_012563.1 hypothetical protein 733546 7764898 CLM_0676 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802915.1 733343 D 536232 CDS YP_002802916.1 226947825 7767838 733965..734969 1 NC_012563.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family protein 734969 7767838 CLM_0679 Clostridium botulinum A2 str. Kyoto CAAX amino terminal protease family protein YP_002802916.1 733965 D 536232 CDS YP_002802917.1 226947826 7764775 complement(735362..736210) 1 NC_012563.1 identified by match to protein family HMM PF00805; pentapeptide repeat family protein 736210 7764775 CLM_0680 Clostridium botulinum A2 str. Kyoto pentapeptide repeat family protein YP_002802917.1 735362 R 536232 CDS YP_002802918.1 226947827 7765370 complement(736534..736695) 1 NC_012563.1 hypothetical protein 736695 7765370 CLM_0681 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802918.1 736534 R 536232 CDS YP_002802919.1 226947828 7767419 737220..737432 1 NC_012563.1 identified by match to protein family HMM PF01381; hypothetical protein 737432 7767419 CLM_0683 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802919.1 737220 D 536232 CDS YP_002802920.1 226947829 7764308 737422..737859 1 NC_012563.1 hypothetical protein 737859 7764308 CLM_0684 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802920.1 737422 D 536232 CDS YP_002802921.1 226947830 7765719 737927..738535 1 NC_012563.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase I 738535 lepB 7765719 lepB Clostridium botulinum A2 str. Kyoto signal peptidase I YP_002802921.1 737927 D 536232 CDS YP_002802922.1 226947831 7766577 739351..740052 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; LytTr family DNA-binding response regulator 740052 7766577 CLM_0686 Clostridium botulinum A2 str. Kyoto LytTr family DNA-binding response regulator YP_002802922.1 739351 D 536232 CDS YP_002802923.1 226947832 7767935 740665..740784 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 740784 7767935 CLM_0687 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802923.1 740665 D 536232 CDS YP_002802924.1 226947833 7765527 740824..740949 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 740949 7765527 CLM_0688 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802924.1 740824 D 536232 CDS YP_002802925.1 226947834 7764304 741647..741793 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 741793 7764304 CLM_0689 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802925.1 741647 D 536232 CDS YP_002802926.1 226947835 7767155 741827..741946 1 NC_012563.1 hypothetical protein 741946 7767155 CLM_0690 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802926.1 741827 D 536232 CDS YP_002802927.1 226947836 7766430 742372..743724 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 743724 7766430 CLM_0691 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002802927.1 742372 D 536232 CDS YP_002802928.1 226947837 7766319 743717..744307 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 744307 7766319 CLM_0692 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802928.1 743717 D 536232 CDS YP_002802929.1 226947838 7765952 744344..744841 1 NC_012563.1 hypothetical protein 744841 7765952 CLM_0693 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802929.1 744344 D 536232 CDS YP_002802930.1 226947839 7765090 744876..746588 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF02463; putative ABC transporter ATP-binding protein/permease 746588 7765090 CLM_0694 Clostridium botulinum A2 str. Kyoto putative ABC transporter ATP-binding protein/permease YP_002802930.1 744876 D 536232 CDS YP_002802931.1 226947840 7764645 746622..747371 1 NC_012563.1 putative lipoprotein 747371 7764645 CLM_0695 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002802931.1 746622 D 536232 CDS YP_002802932.1 226947841 7766742 747394..747873 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 747873 7766742 CLM_0696 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002802932.1 747394 D 536232 CDS YP_002802933.1 226947842 7765045 747870..750338 1 NC_012563.1 identified by match to protein family HMM PF02687; putative ABC transporter permease 750338 7765045 CLM_0697 Clostridium botulinum A2 str. Kyoto putative ABC transporter permease YP_002802933.1 747870 D 536232 CDS YP_002802934.1 226947843 7767159 750353..751033 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 751033 7767159 CLM_0698 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002802934.1 750353 D 536232 CDS YP_002802935.1 226947844 7766740 751601..751864 1 NC_012563.1 hypothetical protein 751864 7766740 CLM_0699 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802935.1 751601 D 536232 CDS YP_002802936.1 226947845 7765823 752193..753059 1 NC_012563.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; degV family protein 753059 7765823 CLM_0700 Clostridium botulinum A2 str. Kyoto degV family protein YP_002802936.1 752193 D 536232 CDS YP_002802937.1 226947846 7765525 753457..753969 1 NC_012563.1 hypothetical protein 753969 7765525 CLM_0701 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802937.1 753457 D 536232 CDS YP_002802938.1 226947847 7765752 complement(754016..754132) 1 NC_012563.1 hypothetical protein 754132 7765752 CLM_0702 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802938.1 754016 R 536232 CDS YP_002802939.1 226947848 7767653 754465..756375 1 NC_012563.1 identified by match to protein family HMM PF00884; sulfatase family protein 756375 7767653 CLM_0703 Clostridium botulinum A2 str. Kyoto sulfatase family protein YP_002802939.1 754465 D 536232 CDS YP_002802940.1 226947849 7764340 complement(756642..758054) 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; sigma-54 dependent transcriptional regulator 758054 7764340 CLM_0704 Clostridium botulinum A2 str. Kyoto sigma-54 dependent transcriptional regulator YP_002802940.1 756642 R 536232 CDS YP_002802941.1 226947850 7764359 complement(758388..759611) 1 NC_012563.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; nucleoside transporter, NupC family 759611 7764359 CLM_0705 Clostridium botulinum A2 str. Kyoto nucleoside transporter, NupC family YP_002802941.1 758388 R 536232 CDS YP_002802942.1 226947851 7765284 760919..762310 1 NC_012563.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 762310 asnC 7765284 asnC Clostridium botulinum A2 str. Kyoto asparaginyl-tRNA synthetase YP_002802942.1 760919 D 536232 CDS YP_002802943.1 226947852 7767093 762584..763039 1 NC_012563.1 identified by match to protein family HMM PF04397; LytR family transcriptional regulator 763039 7767093 CLM_0707 Clostridium botulinum A2 str. Kyoto LytR family transcriptional regulator YP_002802943.1 762584 D 536232 CDS YP_002802944.1 226947853 7768020 763041..763739 1 NC_012563.1 hypothetical protein 763739 7768020 CLM_0708 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802944.1 763041 D 536232 CDS YP_002802945.1 226947854 7764897 764161..765048 1 NC_012563.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445; AraC family transcriptional regulator 765048 7764897 CLM_0709 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002802945.1 764161 D 536232 CDS YP_002802946.1 226947855 7766098 complement(765068..765190) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; integrase, catalytic region 765190 7766098 CLM_0710 Clostridium botulinum A2 str. Kyoto integrase, catalytic region YP_002802946.1 765068 R 536232 CDS YP_002802947.1 226947856 7767079 765484..766395 1 NC_012563.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family protein 766395 7767079 CLM_0711 Clostridium botulinum A2 str. Kyoto CAAX amino terminal protease family protein YP_002802947.1 765484 D 536232 CDS YP_002802948.1 226947857 7765680 766408..766800 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 766800 7765680 CLM_0712 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002802948.1 766408 D 536232 CDS YP_002802949.1 226947858 7767697 767263..768357 1 NC_012563.1 putative lipoprotein 768357 7767697 CLM_0713 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002802949.1 767263 D 536232 CDS YP_002802950.1 226947859 7764588 768532..769215 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 769215 7764588 CLM_0714 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002802950.1 768532 D 536232 CDS YP_002802951.1 226947860 7765363 769220..770641 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 770641 7765363 CLM_0715 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002802951.1 769220 D 536232 CDS YP_002802952.1 226947861 7766220 complement(770766..770939) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 770939 7766220 CLM_0716 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802952.1 770766 R 536232 CDS YP_002802953.1 226947862 7766544 771139..771855 1 NC_012563.1 identified by match to protein family HMM PF02557; D-alanyl-D-alanine carboxypeptidase family protein 771855 7766544 CLM_0717 Clostridium botulinum A2 str. Kyoto D-alanyl-D-alanine carboxypeptidase family protein YP_002802953.1 771139 D 536232 CDS YP_002802954.1 226947863 7767414 771876..772568 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 772568 7767414 CLM_0718 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002802954.1 771876 D 536232 CDS YP_002802955.1 226947864 7768046 772597..773679 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 773679 7768046 CLM_0719 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002802955.1 772597 D 536232 CDS YP_002802956.1 226947865 7767207 complement(773839..774978) 1 NC_012563.1 hypothetical protein 774978 7767207 CLM_0720 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802956.1 773839 R 536232 CDS YP_002802957.1 226947866 7767136 complement(775121..775933) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF08664; response regulator 775933 7767136 CLM_0721 Clostridium botulinum A2 str. Kyoto response regulator YP_002802957.1 775121 R 536232 CDS YP_002802958.1 226947867 7767367 complement(775930..777228) 1 NC_012563.1 identified by match to protein family HMM PF02518; sensor histidine kinase 777228 7767367 CLM_0722 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002802958.1 775930 R 536232 CDS YP_002802959.1 226947868 7766443 777626..778786 1 NC_012563.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210; rod shape-determining protein RodA 778786 rodA 7766443 rodA Clostridium botulinum A2 str. Kyoto rod shape-determining protein RodA YP_002802959.1 777626 D 536232 CDS YP_002802960.1 226947869 7766119 complement(779224..780402) 1 NC_012563.1 identified by match to protein family HMM PF02353; match to protein family HMM PF08241; match to protein family HMM PF08242; cyclopropane-fatty-acyl-phospholipid synthase 780402 cfa 7766119 cfa Clostridium botulinum A2 str. Kyoto cyclopropane-fatty-acyl-phospholipid synthase YP_002802960.1 779224 R 536232 CDS YP_002802961.1 226947870 7764265 780730..781761 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 781761 7764265 CLM_0725 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802961.1 780730 D 536232 CDS YP_002802962.1 226947871 7767680 781931..783610 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; putative ABC transporter ATP-binding protein/permease 783610 7767680 CLM_0726 Clostridium botulinum A2 str. Kyoto putative ABC transporter ATP-binding protein/permease YP_002802962.1 781931 D 536232 CDS YP_002802963.1 226947872 7766835 complement(783848..784474) 1 NC_012563.1 identified by match to protein family HMM PF00302; chloramphenicol acetyltransferase family protein 784474 7766835 CLM_0727 Clostridium botulinum A2 str. Kyoto chloramphenicol acetyltransferase family protein YP_002802963.1 783848 R 536232 CDS YP_002802964.1 226947873 7764749 784645..785262 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00440; TetR family transcriptional regulator 785262 7764749 CLM_0728 Clostridium botulinum A2 str. Kyoto TetR family transcriptional regulator YP_002802964.1 784645 D 536232 CDS YP_002802965.1 226947874 7765857 785365..785835 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 785835 7765857 CLM_0729 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002802965.1 785365 D 536232 CDS YP_002802966.1 226947875 7766302 complement(785902..786231) 1 NC_012563.1 identified by similarity to SP:P37584; match to protein family HMM PF01588; match to protein family HMM TIGR02222; CsaA protein 786231 csaA 7766302 csaA Clostridium botulinum A2 str. Kyoto CsaA protein YP_002802966.1 785902 R 536232 CDS YP_002802967.1 226947876 7767929 complement(786439..787164) 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 787164 7767929 CLM_0731 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002802967.1 786439 R 536232 CDS YP_002802968.1 226947877 7765217 complement(787464..788015) 1 NC_012563.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883; cupin domain-containing protein 788015 7765217 CLM_0732 Clostridium botulinum A2 str. Kyoto cupin domain-containing protein YP_002802968.1 787464 R 536232 CDS YP_002802969.1 226947878 7764346 788272..788862 1 NC_012563.1 identified by match to protein family HMM TIGR00277; HDIG domain-containing protein 788862 7764346 CLM_0733 Clostridium botulinum A2 str. Kyoto HDIG domain-containing protein YP_002802969.1 788272 D 536232 CDS YP_002802970.1 226947879 7766851 789248..790006 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF04397; LytR family transcriptional regulator 790006 7766851 CLM_0734 Clostridium botulinum A2 str. Kyoto LytR family transcriptional regulator YP_002802970.1 789248 D 536232 CDS YP_002802971.1 226947880 7766072 790389..791234 1 NC_012563.1 identified by match to protein family HMM PF00005; bacitracin transport ATP-binding protein BcrA 791234 7766072 CLM_0735 Clostridium botulinum A2 str. Kyoto bacitracin transport ATP-binding protein BcrA YP_002802971.1 790389 D 536232 CDS YP_002802972.1 226947881 7765861 791234..791965 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 791965 7765861 CLM_0736 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802972.1 791234 D 536232 CDS YP_002802973.1 226947882 7765047 complement(792179..793402) 1 NC_012563.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 793402 atcC 7765047 atcC Clostridium botulinum A2 str. Kyoto allantoate amidohydrolase YP_002802973.1 792179 R 536232 CDS YP_002802974.1 226947883 7767658 793963..794349 1 NC_012563.1 identified by match to protein family HMM PF00903; lactoylglutathione lyase 794349 7767658 CLM_0738 Clostridium botulinum A2 str. Kyoto lactoylglutathione lyase YP_002802974.1 793963 D 536232 CDS YP_002802975.1 226947884 7766513 794694..796589 1 NC_012563.1 identified by match to protein family HMM PF00488; MutS domain-containing protein 796589 7766513 CLM_0739 Clostridium botulinum A2 str. Kyoto MutS domain-containing protein YP_002802975.1 794694 D 536232 CDS YP_002802976.1 226947885 7765652 797422..797772 1 NC_012563.1 identified by similarity to GB:CAL82185.1; hypothetical protein 797772 7765652 CLM_0741 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802976.1 797422 D 536232 CDS YP_002802977.1 226947886 7765495 complement(797859..798332) 1 NC_012563.1 identified by similarity to GB:CAA50578.1; match to protein family HMM PF01243; putative 5-nitroimidazole antibiotic resistance protein 798332 7765495 CLM_0742 Clostridium botulinum A2 str. Kyoto putative 5-nitroimidazole antibiotic resistance protein YP_002802977.1 797859 R 536232 CDS YP_002802978.1 226947887 7765084 complement(798355..798768) 1 NC_012563.1 identified by match to protein family HMM PF04304; hypothetical protein 798768 7765084 CLM_0743 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802978.1 798355 R 536232 CDS YP_002802979.1 226947888 7765982 complement(798738..798857) 1 NC_012563.1 membrane protein 798857 7765982 CLM_0744 Clostridium botulinum A2 str. Kyoto membrane protein YP_002802979.1 798738 R 536232 CDS YP_002802980.1 226947889 7766680 799393..799887 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase family protein 799887 7766680 CLM_0745 Clostridium botulinum A2 str. Kyoto pyridoxamine 5'-phosphate oxidase family protein YP_002802980.1 799393 D 536232 CDS YP_002802981.1 226947890 7766530 complement(800095..800406) 1 NC_012563.1 hypothetical protein 800406 7766530 CLM_0746 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802981.1 800095 R 536232 CDS YP_002802982.1 226947891 7767144 complement(800545..801954) 1 NC_012563.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 801954 7767144 CLM_0747 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002802982.1 800545 R 536232 CDS YP_002802983.1 226947892 7767620 802147..802455 1 NC_012563.1 hypothetical protein 802455 7767620 CLM_0748 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802983.1 802147 D 536232 CDS YP_002802984.1 226947893 7767872 802857..804134 1 NC_012563.1 identified by similarity to SP:P25888; match to protein family HMM PF00270; match to protein family HMM PF00271; ATP-dependent RNA helicase RhlE 804134 rhlE 7767872 rhlE Clostridium botulinum A2 str. Kyoto ATP-dependent RNA helicase RhlE YP_002802984.1 802857 D 536232 CDS YP_002802985.1 226947894 7764269 804733..805221 1 NC_012563.1 identified by match to protein family HMM PF02915; putative rubrerythrin 805221 7764269 CLM_0750 Clostridium botulinum A2 str. Kyoto putative rubrerythrin YP_002802985.1 804733 D 536232 CDS YP_002802986.1 226947895 7765346 805391..805828 1 NC_012563.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 805828 7765346 CLM_0751 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002802986.1 805391 D 536232 CDS YP_002802987.1 226947896 7767119 805856..807289 1 NC_012563.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; drug resistance transporter, EmrB/QacA family 807289 7767119 CLM_0752 Clostridium botulinum A2 str. Kyoto drug resistance transporter, EmrB/QacA family YP_002802987.1 805856 D 536232 CDS YP_002802988.1 226947897 7767832 complement(807411..808601) 1 NC_012563.1 hypothetical protein 808601 7767832 CLM_0753 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802988.1 807411 R 536232 CDS YP_002802989.1 226947898 7764731 808726..809601 1 NC_012563.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 809601 7764731 CLM_0754 Clostridium botulinum A2 str. Kyoto LysR family transcriptional regulator YP_002802989.1 808726 D 536232 CDS YP_002802990.1 226947899 7767919 809640..811214 1 NC_012563.1 identified by match to protein family HMM PF08011; hypothetical protein 811214 7767919 CLM_0755 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802990.1 809640 D 536232 CDS YP_002802991.1 226947900 7766757 811398..811619 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 811619 7766757 CLM_0756 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802991.1 811398 D 536232 CDS YP_002802992.1 226947901 7765626 811609..811926 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 811926 7765626 CLM_0757 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802992.1 811609 D 536232 CDS YP_002802993.1 226947902 7767857 811993..812661 1 NC_012563.1 identified by similarity to SP:P0AFY2; match to protein family HMM PF02698; putative SanA protein 812661 7767857 CLM_0758 Clostridium botulinum A2 str. Kyoto putative SanA protein YP_002802993.1 811993 D 536232 CDS YP_002802994.1 226947903 7766083 complement(815797..816195) 1 NC_012563.1 identified by match to protein family HMM PF00293; putative mutator mutT protein 816195 7766083 CLM_0761 Clostridium botulinum A2 str. Kyoto putative mutator mutT protein YP_002802994.1 815797 R 536232 CDS YP_002802995.1 226947904 7764551 816551..817801 1 NC_012563.1 hypothetical protein 817801 7764551 CLM_0762 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802995.1 816551 D 536232 CDS YP_002802996.1 226947905 7765591 818195..821743 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 821743 7765591 CLM_0763 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802996.1 818195 D 536232 CDS YP_002802997.1 226947906 7766456 821769..824489 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 824489 7766456 CLM_0764 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802997.1 821769 D 536232 CDS YP_002802998.1 226947907 7765510 complement(824517..825254) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 825254 7765510 CLM_0765 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802998.1 824517 R 536232 CDS YP_002802999.1 226947908 7766144 complement(825653..826144) 1 NC_012563.1 hypothetical protein 826144 7766144 CLM_0766 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002802999.1 825653 R 536232 CDS YP_002803000.1 226947909 7767255 826616..827455 1 NC_012563.1 identified by similarity to SP:P39805; match to protein family HMM PF00874; match to protein family HMM PF03123; transcriptional antiterminator, LicT 827455 licT 7767255 licT Clostridium botulinum A2 str. Kyoto transcriptional antiterminator, LicT YP_002803000.1 826616 D 536232 CDS YP_002803001.1 226947910 7764924 827663..829504 1 NC_012563.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00830; match to protein family HMM TIGR01995; PTS system beta-glucoside-specific transporter subunit IIABC 829504 7764924 CLM_0768 Clostridium botulinum A2 str. Kyoto PTS system beta-glucoside-specific transporter subunit IIABC YP_002803001.1 827663 D 536232 CDS YP_002803002.1 226947911 7766051 829516..830334 1 NC_012563.1 identified by match to protein family HMM PF02811; PHP domain-containing protein 830334 7766051 CLM_0769 Clostridium botulinum A2 str. Kyoto PHP domain-containing protein YP_002803002.1 829516 D 536232 CDS YP_002803003.1 226947912 7766768 830510..830647 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 830647 7766768 CLM_0770 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803003.1 830510 D 536232 CDS YP_002803004.1 226947913 7767813 830966..831676 1 NC_012563.1 identified by match to protein family HMM PF00027; match to protein family HMM PF00325; Crp/Fnr family transcriptional regulator 831676 7767813 CLM_0771 Clostridium botulinum A2 str. Kyoto Crp/Fnr family transcriptional regulator YP_002803004.1 830966 D 536232 CDS YP_002803005.1 226947914 7767219 831955..833187 1 NC_012563.1 identified by match to protein family HMM PF00258; match to protein family HMM PF00753; metallo-beta-lactamase family protein 833187 7767219 CLM_0772 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002803005.1 831955 D 536232 CDS YP_002803006.1 226947915 7767066 833247..833945 1 NC_012563.1 identified by match to protein family HMM PF01814; match to protein family HMM PF04405; putative scdA protein 833945 7767066 CLM_0773 Clostridium botulinum A2 str. Kyoto putative scdA protein YP_002803006.1 833247 D 536232 CDS YP_002803007.1 226947916 7765455 833971..834726 1 NC_012563.1 identified by match to protein family HMM PF01814; match to protein family HMM PF04282; hypothetical protein 834726 7765455 CLM_0774 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803007.1 833971 D 536232 CDS YP_002803008.1 226947917 7767565 complement(834799..835218) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 835218 7767565 CLM_0775 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803008.1 834799 R 536232 CDS YP_002803009.1 226947918 7764844 835880..837064 1 NC_012563.1 identified by match to protein family HMM PF03616; match to protein family HMM TIGR00210; sodium/glutamate symporter 837064 gltS 7764844 gltS Clostridium botulinum A2 str. Kyoto sodium/glutamate symporter YP_002803009.1 835880 D 536232 CDS YP_002803010.1 226947919 7765688 complement(837151..837267) 1 NC_012563.1 transposase 837267 7765688 CLM_0777 Clostridium botulinum A2 str. Kyoto transposase YP_002803010.1 837151 R 536232 CDS YP_002803011.1 226947920 7767098 837673..838140 1 NC_012563.1 hypothetical protein 838140 7767098 CLM_0778 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803011.1 837673 D 536232 CDS YP_002803012.1 226947921 7767351 838147..839490 1 NC_012563.1 hypothetical protein 839490 7767351 CLM_0779 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803012.1 838147 D 536232 CDS YP_002803013.1 226947922 7767746 839757..840743 1 NC_012563.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 840743 7767746 CLM_0780 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002803013.1 839757 D 536232 CDS YP_002803014.1 226947923 7766605 841085..841978 1 NC_012563.1 identified by match to protein family HMM PF02653; ABC transporter permease 841978 7766605 CLM_0781 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002803014.1 841085 D 536232 CDS YP_002803015.1 226947924 7765743 841941..842696 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 842696 7765743 CLM_0782 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803015.1 841941 D 536232 CDS YP_002803016.1 226947925 7764880 842727..843698 1 NC_012563.1 identified by match to protein family HMM PF04392; putative ABC transporter substrate-binding protein 843698 7764880 CLM_0783 Clostridium botulinum A2 str. Kyoto putative ABC transporter substrate-binding protein YP_002803016.1 842727 D 536232 CDS YP_002803017.1 226947926 7767415 843712..844092 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 844092 7767415 CLM_0784 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803017.1 843712 D 536232 CDS YP_002803018.1 226947927 7764354 844440..844577 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 844577 7764354 CLM_0785 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803018.1 844440 D 536232 CDS YP_002803019.1 226947928 7765212 844812..845489 1 NC_012563.1 non-specific serine/threonine protein kinase 845489 7765212 CLM_0786 Clostridium botulinum A2 str. Kyoto non-specific serine/threonine protein kinase YP_002803019.1 844812 D 536232 CDS YP_002803020.1 226947929 7766534 complement(846074..847495) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 847495 7766534 CLM_0787 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803020.1 846074 R 536232 CDS YP_002803021.1 226947930 7764622 complement(847492..848055) 1 NC_012563.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 848055 7764622 CLM_0788 Clostridium botulinum A2 str. Kyoto RNA polymerase factor sigma-70 YP_002803021.1 847492 R 536232 CDS YP_002803022.1 226947931 7765476 848496..849434 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01207; dihydrouridine synthase family protein 849434 7765476 CLM_0789 Clostridium botulinum A2 str. Kyoto dihydrouridine synthase family protein YP_002803022.1 848496 D 536232 CDS YP_002803023.1 226947932 7766826 849591..850055 1 NC_012563.1 identified by match to protein family HMM PF01272; match to protein family HMM PF03449; match to protein family HMM TIGR01462; transcription elongation factor GreA 850055 greA 7766826 greA Clostridium botulinum A2 str. Kyoto transcription elongation factor GreA YP_002803023.1 849591 D 536232 CDS YP_002803024.1 226947933 7767714 850223..850975 1 NC_012563.1 hypothetical protein 850975 7767714 CLM_0791 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803024.1 850223 D 536232 CDS YP_002803025.1 226947934 7765775 851251..852735 1 NC_012563.1 identified by match to protein family HMM PF02384; type I restriction modification system M subunit 852735 7765775 CLM_0792 Clostridium botulinum A2 str. Kyoto type I restriction modification system M subunit YP_002803025.1 851251 D 536232 CDS YP_002803026.1 226947935 7767028 852716..853903 1 NC_012563.1 identified by match to protein family HMM PF01420; restriction modification system DNA specificity domain-containing protein 853903 7767028 CLM_0793 Clostridium botulinum A2 str. Kyoto restriction modification system DNA specificity domain-containing protein YP_002803026.1 852716 D 536232 CDS YP_002803027.1 226947936 7766372 854198..855013 1 NC_012563.1 hypothetical protein 855013 7766372 CLM_0794 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803027.1 854198 D 536232 CDS YP_002803028.1 226947937 7767578 855118..858465 1 NC_012563.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851; putative type I restriction-modification system, R subunit 858465 7767578 CLM_0795 Clostridium botulinum A2 str. Kyoto putative type I restriction-modification system, R subunit YP_002803028.1 855118 D 536232 CDS YP_002803029.1 226947938 7764496 858557..858817 1 NC_012563.1 identified by match to protein family HMM PF04994; tfoX domain-containing protein 858817 7764496 CLM_0796 Clostridium botulinum A2 str. Kyoto tfoX domain-containing protein YP_002803029.1 858557 D 536232 CDS YP_002803030.1 226947939 7765255 858915..859370 1 NC_012563.1 identified by match to protein family HMM PF06445; DNA gyrase inhibitory protein, GyrI 859370 7765255 CLM_0797 Clostridium botulinum A2 str. Kyoto DNA gyrase inhibitory protein, GyrI YP_002803030.1 858915 D 536232 CDS YP_002803031.1 226947940 7766650 859967..860893 1 NC_012563.1 identified by match to protein family HMM PF00144; beta-lactamase 860893 7766650 CLM_0798 Clostridium botulinum A2 str. Kyoto beta-lactamase YP_002803031.1 859967 D 536232 CDS YP_002803032.1 226947941 7765088 861099..861473 1 NC_012563.1 identified by match to protein family HMM PF03965; penicillinase repressor 861473 blaI 7765088 blaI Clostridium botulinum A2 str. Kyoto penicillinase repressor YP_002803032.1 861099 D 536232 CDS YP_002803033.1 226947942 7765959 861484..863265 1 NC_012563.1 identified by match to protein family HMM PF00905; match to protein family HMM PF05569; putative beta-lactamase-inducing penicillin-binding protein 863265 7765959 CLM_0800 Clostridium botulinum A2 str. Kyoto putative beta-lactamase-inducing penicillin-binding protein YP_002803033.1 861484 D 536232 CDS YP_002803034.1 226947943 7767707 complement(863509..863640) 1 NC_012563.1 hypothetical protein 863640 7767707 CLM_0801 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803034.1 863509 R 536232 CDS YP_002803035.1 226947944 7766806 864041..864862 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 864862 7766806 CLM_0802 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002803035.1 864041 D 536232 CDS YP_002803036.1 226947945 7766510 865398..866387 1 NC_012563.1 identified by match to protein family HMM PF01497; iron chelate uptake transporter FeCT family ABC transporter periplasmic-binding protein 866387 7766510 CLM_0803 Clostridium botulinum A2 str. Kyoto iron chelate uptake transporter FeCT family ABC transporter periplasmic-binding protein YP_002803036.1 865398 D 536232 CDS YP_002803037.1 226947946 7765581 866483..867523 1 NC_012563.1 identified by similarity to SP:P49936; match to protein family HMM PF01032; ferrichrome transport system permease FhuB 867523 fhuB 7765581 fhuB Clostridium botulinum A2 str. Kyoto ferrichrome transport system permease FhuB YP_002803037.1 866483 D 536232 CDS YP_002803038.1 226947947 7765961 867523..868563 1 NC_012563.1 identified by similarity to SP:P49937; match to protein family HMM PF01032; ferrichrome transport system permease FhuG 868563 fhuG 7765961 fhuG Clostridium botulinum A2 str. Kyoto ferrichrome transport system permease FhuG YP_002803038.1 867523 D 536232 CDS YP_002803039.1 226947948 7765057 868791..869576 1 NC_012563.1 identified by similarity to SP:P49938; match to protein family HMM PF00005; ferrichrome transport ATP-binding protein FhuC 869576 fhuC 7765057 fhuC Clostridium botulinum A2 str. Kyoto ferrichrome transport ATP-binding protein FhuC YP_002803039.1 868791 D 536232 CDS YP_002803040.1 226947949 7767203 869606..870355 1 NC_012563.1 identified by match to protein family HMM PF00142; nitrogenase iron protein 870355 nifH 7767203 nifH Clostridium botulinum A2 str. Kyoto nitrogenase iron protein YP_002803040.1 869606 D 536232 CDS YP_002803041.1 226947950 7766363 870358..871635 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 871635 7766363 CLM_0808 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803041.1 870358 D 536232 CDS YP_002803042.1 226947951 7766649 871667..872905 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 872905 7766649 CLM_0809 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803042.1 871667 D 536232 CDS YP_002803043.1 226947952 7767309 873350..875362 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis protein 875362 7767309 CLM_0810 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002803043.1 873350 D 536232 CDS YP_002803044.1 226947953 7764894 875414..875587 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 875587 7764894 CLM_0811 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803044.1 875414 D 536232 CDS YP_002803045.1 226947954 7767379 complement(875658..877067) 1 NC_012563.1 hypothetical protein 877067 7767379 CLM_0813 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803045.1 875658 R 536232 CDS YP_002803046.1 226947955 7766057 complement(877207..877323) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 877323 7766057 CLM_0814 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803046.1 877207 R 536232 CDS YP_002803047.1 226947956 7767373 877491..878603 1 NC_012563.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 878603 gcvT 7767373 gcvT Clostridium botulinum A2 str. Kyoto glycine cleavage system aminomethyltransferase T YP_002803047.1 877491 D 536232 CDS YP_002803048.1 226947957 7766667 878728..879120 1 NC_012563.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 879120 gcvH 7766667 gcvH Clostridium botulinum A2 str. Kyoto glycine cleavage system protein H YP_002803048.1 878728 D 536232 CDS YP_002803049.1 226947958 7765831 879123..880463 1 NC_012563.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 880463 gcvPA 7765831 gcvPA Clostridium botulinum A2 str. Kyoto glycine dehydrogenase subunit 1 YP_002803049.1 879123 D 536232 CDS YP_002803050.1 226947959 7765433 880463..881917 1 NC_012563.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 881917 gcvPB 7765433 gcvPB Clostridium botulinum A2 str. Kyoto glycine dehydrogenase subunit 2 YP_002803050.1 880463 D 536232 CDS YP_002803051.1 226947960 7764671 882106..883494 1 NC_012563.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350; dihydrolipoyl dehydrogenase 883494 lpdA 7764671 lpdA Clostridium botulinum A2 str. Kyoto dihydrolipoyl dehydrogenase YP_002803051.1 882106 D 536232 CDS YP_002803052.1 226947961 7767287 883643..884620 1 NC_012563.1 identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545; putative lipoate-protein ligase A 884620 7767287 CLM_0820 Clostridium botulinum A2 str. Kyoto putative lipoate-protein ligase A YP_002803052.1 883643 D 536232 CDS YP_002803053.1 226947962 7766299 885002..885259 1 NC_012563.1 hypothetical protein 885259 7766299 CLM_0821 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803053.1 885002 D 536232 CDS YP_002803054.1 226947963 7765875 885652..886218 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 886218 7765875 CLM_0822 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803054.1 885652 D 536232 CDS YP_002803055.1 226947964 7764796 886391..886573 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 886573 7764796 CLM_0823 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803055.1 886391 D 536232 CDS YP_002803056.1 226947965 7767985 886605..887132 1 NC_012563.1 transposase, mutator type 887132 7767985 CLM_0824 Clostridium botulinum A2 str. Kyoto transposase, mutator type YP_002803056.1 886605 D 536232 CDS YP_002803057.1 226947966 7767137 887149..887847 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 887847 7767137 CLM_0825 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002803057.1 887149 D 536232 CDS YP_002803058.1 226947967 7767477 887832..888881 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 888881 7767477 CLM_0826 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803058.1 887832 D 536232 CDS YP_002803059.1 226947968 7764484 888954..889637 1 NC_012563.1 identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease MacB 889637 7764484 CLM_0827 Clostridium botulinum A2 str. Kyoto macrolide export ATP-binding/permease MacB YP_002803059.1 888954 D 536232 CDS YP_002803060.1 226947969 7765607 889634..891436 1 NC_012563.1 identified by match to protein family HMM PF02687; ABC transporter permease 891436 7765607 CLM_0828 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002803060.1 889634 D 536232 CDS YP_002803061.1 226947970 7766877 891624..892112 1 NC_012563.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 892112 7766877 CLM_0829 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002803061.1 891624 D 536232 CDS YP_002803062.1 226947971 7765391 892344..892931 1 NC_012563.1 identified by match to protein family HMM PF03358; flavin reductase 892931 7765391 CLM_0830 Clostridium botulinum A2 str. Kyoto flavin reductase YP_002803062.1 892344 D 536232 CDS YP_002803063.1 226947972 7766444 893293..893427 1 NC_012563.1 hypothetical protein 893427 7766444 CLM_0831 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803063.1 893293 D 536232 CDS YP_002803064.1 226947973 7767763 894260..895024 1 NC_012563.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 895024 7767763 CLM_0834 Clostridium botulinum A2 str. Kyoto MerR family transcriptional regulator YP_002803064.1 894260 D 536232 CDS YP_002803065.1 226947974 7766967 895076..895807 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 895807 7766967 CLM_0835 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803065.1 895076 D 536232 CDS YP_002803066.1 226947975 7766865 895794..896537 1 NC_012563.1 identified by match to protein family HMM PF01061; putative drug resistance ABC-2 type transporter, permease 896537 7766865 CLM_0836 Clostridium botulinum A2 str. Kyoto putative drug resistance ABC-2 type transporter, permease YP_002803066.1 895794 D 536232 CDS YP_002803067.1 226947976 7767776 complement(896998..897879) 1 NC_012563.1 identified by match to protein family HMM PF00892; integral membrane protein 897879 7767776 CLM_0837 Clostridium botulinum A2 str. Kyoto integral membrane protein YP_002803067.1 896998 R 536232 CDS YP_002803068.1 226947977 7764561 898017..898565 1 NC_012563.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883; cupin domain-containing protein 898565 7764561 CLM_0838 Clostridium botulinum A2 str. Kyoto cupin domain-containing protein YP_002803068.1 898017 D 536232 CDS YP_002803069.1 226947978 7765531 899568..900959 1 NC_012563.1 hypothetical protein 900959 7765531 CLM_0839 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803069.1 899568 D 536232 CDS YP_002803070.1 226947979 7766405 901326..901676 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00583; GNAT family acetyltransferase 901676 7766405 CLM_0840 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803070.1 901326 D 536232 CDS YP_002803071.1 226947980 7767290 902060..902176 1 NC_012563.1 hypothetical protein 902176 7767290 CLM_0841 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803071.1 902060 D 536232 CDS YP_002803072.1 226947981 7764568 902232..903197 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 903197 7764568 CLM_0842 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002803072.1 902232 D 536232 CDS YP_002803073.1 226947982 7765448 903432..903596 1 NC_012563.1 hypothetical protein 903596 7765448 CLM_0843 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803073.1 903432 D 536232 CDS YP_002803074.1 226947983 7766397 903598..903858 1 NC_012563.1 hypothetical protein 903858 7766397 CLM_0844 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803074.1 903598 D 536232 CDS YP_002803075.1 226947984 7767196 complement(903978..904112) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Na+ driven multidrug efflux pump 904112 7767196 CLM_0845 Clostridium botulinum A2 str. Kyoto Na+ driven multidrug efflux pump YP_002803075.1 903978 R 536232 CDS YP_002803076.1 226947985 7768017 904264..904473 1 NC_012563.1 hypothetical protein 904473 7768017 CLM_0846 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803076.1 904264 D 536232 CDS YP_002803077.1 226947986 7765126 904470..904892 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 904892 7765126 CLM_0847 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803077.1 904470 D 536232 CDS YP_002803078.1 226947987 7765759 905113..905520 1 NC_012563.1 identified by match to protein family HMM PF00903; lactoylglutathione lyase 905520 7765759 CLM_0848 Clostridium botulinum A2 str. Kyoto lactoylglutathione lyase YP_002803078.1 905113 D 536232 CDS YP_002803079.1 226947988 7766853 905617..906381 1 NC_012563.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 906381 7766853 CLM_0849 Clostridium botulinum A2 str. Kyoto MerR family transcriptional regulator YP_002803079.1 905617 D 536232 CDS YP_002803080.1 226947989 7765397 906487..906633 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; MerR family transcriptional regulator 906633 7765397 CLM_0850 Clostridium botulinum A2 str. Kyoto MerR family transcriptional regulator YP_002803080.1 906487 D 536232 CDS YP_002803081.1 226947990 7766233 906686..908923 1 NC_012563.1 identified by match to protein family HMM PF00005; putative drug resistance ABC transporter ATP-binding protein 908923 7766233 CLM_0851 Clostridium botulinum A2 str. Kyoto putative drug resistance ABC transporter ATP-binding protein YP_002803081.1 906686 D 536232 CDS YP_002803082.1 226947991 7767726 909118..911376 1 NC_012563.1 identified by similarity to GB:BAE82969.1; hypothetical protein 911376 7767726 CLM_0852 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803082.1 909118 D 536232 CDS YP_002803083.1 226947992 7764601 complement(911490..912197) 1 NC_012563.1 identified by match to protein family HMM PF07505; hypothetical protein 912197 7764601 CLM_0853 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803083.1 911490 R 536232 CDS YP_002803084.1 226947993 7764910 complement(912296..913168) 1 NC_012563.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445; AraC family transcriptional regulator 913168 7764910 CLM_0854 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002803084.1 912296 R 536232 CDS YP_002803085.1 226947994 7765665 913845..915821 1 NC_012563.1 hypothetical protein 915821 7765665 CLM_0855 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803085.1 913845 D 536232 CDS YP_002803086.1 226947995 7768098 complement(916309..917307) 1 NC_012563.1 identified by match to protein family HMM PF08541; match to protein family HMM PF08545; 3-oxoacyl-ACP synthase III 917307 7768098 CLM_0856 Clostridium botulinum A2 str. Kyoto 3-oxoacyl-ACP synthase III YP_002803086.1 916309 R 536232 CDS YP_002803087.1 226947996 7766949 917556..919022 1 NC_012563.1 identified by match to protein family HMM PF00015; methyl-accepting chemotaxis protein 919022 7766949 CLM_0857 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002803087.1 917556 D 536232 CDS YP_002803088.1 226947997 7766886 919516..919806 1 NC_012563.1 hypothetical protein 919806 7766886 CLM_0858 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803088.1 919516 D 536232 CDS YP_002803089.1 226947998 7765737 complement(919860..919973) 1 NC_012563.1 hypothetical protein 919973 7765737 CLM_0859 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803089.1 919860 R 536232 CDS YP_002803090.1 226947999 7764909 920005..921558 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 921558 7764909 CLM_0860 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803090.1 920005 D 536232 CDS YP_002803091.1 226948000 7766514 921716..922342 1 NC_012563.1 identified by match to protein family HMM PF01965; DJ-1/PfpI family protein 922342 7766514 CLM_0861 Clostridium botulinum A2 str. Kyoto DJ-1/PfpI family protein YP_002803091.1 921716 D 536232 CDS YP_002803092.1 226948001 7764447 922406..922537 1 NC_012563.1 identified by similarity to GB:ABD14706.1; hypothetical protein 922537 7764447 CLM_0862 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803092.1 922406 D 536232 CDS YP_002803093.1 226948002 7767243 923215..924507 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 924507 7767243 CLM_0863 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803093.1 923215 D 536232 CDS YP_002803094.1 226948003 7766983 924507..924983 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 924983 7766983 CLM_0864 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803094.1 924507 D 536232 CDS YP_002803095.1 226948004 7765816 925145..926890 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 926890 7765816 CLM_0865 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803095.1 925145 D 536232 CDS YP_002803096.1 226948005 7767060 complement(927608..928516) 1 NC_012563.1 identified by match to protein family HMM PF00291; cysteine synthase family protein 928516 7767060 CLM_0866 Clostridium botulinum A2 str. Kyoto cysteine synthase family protein YP_002803096.1 927608 R 536232 CDS YP_002803097.1 226948006 7766811 complement(928500..928952) 1 NC_012563.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 928952 luxS 7766811 luxS Clostridium botulinum A2 str. Kyoto S-ribosylhomocysteinase YP_002803097.1 928500 R 536232 CDS YP_002803098.1 226948007 7765697 complement(928954..930096) 1 NC_012563.1 identified by match to protein family HMM PF01053; match to protein family HMM PF01212; cystathionine beta-lyase 930096 metC 7765697 metC Clostridium botulinum A2 str. Kyoto cystathionine beta-lyase YP_002803098.1 928954 R 536232 CDS YP_002803099.1 226948008 7767556 complement(930197..930823) 1 NC_012563.1 identified by match to protein family HMM PF01209; match to protein family HMM PF02390; match to protein family HMM PF08241; match to protein family HMM PF08242; hypothetical protein 930823 7767556 CLM_0869 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803099.1 930197 R 536232 CDS YP_002803100.1 226948009 7767914 complement(931379..931492) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 931492 7767914 CLM_0870 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803100.1 931379 R 536232 CDS YP_002803101.1 226948010 7767297 931730..933583 1 NC_012563.1 identified by match to protein family HMM PF00704; glycosyl hydrolase, family 18 933583 7767297 CLM_0871 Clostridium botulinum A2 str. Kyoto glycosyl hydrolase, family 18 YP_002803101.1 931730 D 536232 CDS YP_002803102.1 226948011 7764662 933835..934608 1 NC_012563.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242; YbaJ 934608 7764662 CLM_0872 Clostridium botulinum A2 str. Kyoto YbaJ YP_002803102.1 933835 D 536232 CDS YP_002803103.1 226948012 7765585 934830..935042 1 NC_012563.1 radical SAM domain-containing protein 935042 7765585 CLM_0873 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002803103.1 934830 D 536232 CDS YP_002803104.1 226948013 7766906 935340..936212 1 NC_012563.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445; transcription activator, effector binding 936212 7766906 CLM_0874 Clostridium botulinum A2 str. Kyoto transcription activator, effector binding YP_002803104.1 935340 D 536232 CDS YP_002803105.1 226948014 7767758 936515..936754 1 NC_012563.1 identified by match to protein family HMM PF00403; hypothetical protein 936754 7767758 CLM_0875 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803105.1 936515 D 536232 CDS YP_002803106.1 226948015 7765869 complement(936862..937194) 1 NC_012563.1 hypothetical protein 937194 7765869 CLM_0876 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803106.1 936862 R 536232 CDS YP_002803107.1 226948016 7766778 complement(937282..937782) 1 NC_012563.1 identified by match to protein family HMM PF06172; hypothetical protein 937782 7766778 CLM_0877 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803107.1 937282 R 536232 CDS YP_002803108.1 226948017 7767385 complement(938333..938941) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 938941 7767385 CLM_0878 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803108.1 938333 R 536232 CDS YP_002803109.1 226948018 7765037 complement(939034..939456) 1 NC_012563.1 identified by match to protein family HMM PF01381; putative DNA-binding protein 939456 7765037 CLM_0879 Clostridium botulinum A2 str. Kyoto putative DNA-binding protein YP_002803109.1 939034 R 536232 CDS YP_002803110.1 226948019 7765646 939600..939863 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 939863 7765646 CLM_0880 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002803110.1 939600 D 536232 CDS YP_002803111.1 226948020 7766276 939901..941040 1 NC_012563.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446; phage protein 941040 7766276 CLM_0881 Clostridium botulinum A2 str. Kyoto phage protein YP_002803111.1 939901 D 536232 CDS YP_002803112.1 226948021 7765413 941059..941598 1 NC_012563.1 identified by match to protein family HMM TIGR02937; sigma-70 family RNA polymerase sigma factor 941598 7765413 CLM_0882 Clostridium botulinum A2 str. Kyoto sigma-70 family RNA polymerase sigma factor YP_002803112.1 941059 D 536232 CDS YP_002803113.1 226948022 7766343 941698..942054 1 NC_012563.1 identified by match to protein family HMM TIGR02436; hypothetical protein 942054 7766343 CLM_0883 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803113.1 941698 D 536232 CDS YP_002803114.1 226948023 7766700 942153..942332 1 NC_012563.1 hypothetical protein 942332 7766700 CLM_0884 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803114.1 942153 D 536232 CDS YP_002803115.1 226948024 7764595 942446..942613 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 942613 7764595 CLM_0885 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803115.1 942446 D 536232 CDS YP_002803116.1 226948025 7764665 942786..943424 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 943424 7764665 CLM_0886 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803116.1 942786 D 536232 CDS YP_002803117.1 226948026 7765568 943843..944064 1 NC_012563.1 hypothetical protein 944064 7765568 CLM_0887 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803117.1 943843 D 536232 CDS YP_002803118.1 226948027 7766191 944084..944311 1 NC_012563.1 hypothetical protein 944311 7766191 CLM_0888 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803118.1 944084 D 536232 CDS YP_002803119.1 226948028 7767537 944570..944935 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by similarity to SP:Q01257; arsenate reductase family protein 944935 7767537 CLM_0889 Clostridium botulinum A2 str. Kyoto arsenate reductase family protein YP_002803119.1 944570 D 536232 CDS YP_002803120.1 226948029 7765374 944989..945117 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 945117 7765374 CLM_0890 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803120.1 944989 D 536232 CDS YP_002803121.1 226948030 7766511 complement(945162..946634) 1 NC_012563.1 toxin complex component ORF-X3 946634 7766511 CLM_0891 Clostridium botulinum A2 str. Kyoto toxin complex component ORF-X3 YP_002803121.1 945162 R 536232 CDS YP_002803122.1 226948031 7768121 complement(946673..948925) 1 NC_012563.1 toxin complex component ORF-X2 948925 7768121 CLM_0892 Clostridium botulinum A2 str. Kyoto toxin complex component ORF-X2 YP_002803122.1 946673 R 536232 CDS YP_002803123.1 226948032 7764271 complement(948939..949367) 1 NC_012563.1 toxin complex component ORF-X1 949367 7764271 CLM_0893 Clostridium botulinum A2 str. Kyoto toxin complex component ORF-X1 YP_002803123.1 948939 R 536232 CDS YP_002803124.1 226948033 7764923 complement(950593..951129) 1 NC_012563.1 identified by match to protein family HMM PF08281; match to protein family HMM TIGR02937; match to protein family HMM TIGR03209; transcriptional regulator BotR, P-21 951129 botR 7764923 botR Clostridium botulinum A2 str. Kyoto transcriptional regulator BotR, P-21 YP_002803124.1 950593 R 536232 CDS YP_002803125.1 226948034 7766043 951429..952679 1 NC_012563.1 identified by similarity to GB:ABC26000.1; match to protein family HMM PF06597; P-47 protein 952679 p47 7766043 p47 Clostridium botulinum A2 str. Kyoto P-47 protein YP_002803125.1 951429 D 536232 CDS YP_002803126.1 226948035 7765518 952695..956174 1 NC_012563.1 identified by match to protein family HMM PF01742; match to protein family HMM PF07953; match to protein family HMM PF08470; botulinum neurotoxin type A2, nontoxic-nonhemagglutinin component, NTNH 956174 ntnH 7765518 ntnH Clostridium botulinum A2 str. Kyoto botulinum neurotoxin type A2, nontoxic-nonhemagglutinin component, NTNH YP_002803126.1 952695 D 536232 CDS YP_002803127.1 226948036 7766540 956218..960108 1 NC_012563.1 identified by similarity to SP:P10845; match to protein family HMM PF01742; match to protein family HMM PF07951; match to protein family HMM PF07952; match to protein family HMM PF07953; bontoxilysin A 960108 botA 7766540 botA Clostridium botulinum A2 str. Kyoto bontoxilysin A YP_002803127.1 956218 D 536232 CDS YP_002803128.1 226948037 7764584 960771..960890 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 960890 7764584 CLM_0898 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803128.1 960771 D 536232 CDS YP_002803129.1 226948038 7764892 961128..962078 1 NC_012563.1 identified by match to protein family HMM PF01183; match to protein family HMM PF01471; LycA 962078 7764892 CLM_0899 Clostridium botulinum A2 str. Kyoto LycA YP_002803129.1 961128 D 536232 CDS YP_002803130.1 226948039 7765773 962631..962753 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 962753 7765773 CLM_0900 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803130.1 962631 D 536232 CDS YP_002803131.1 226948040 7767157 962766..962993 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 962993 7767157 CLM_0901 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803131.1 962766 D 536232 CDS YP_002803132.1 226948041 7764797 963069..963200 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 963200 7764797 CLM_0902 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803132.1 963069 D 536232 CDS YP_002803133.1 226948042 7765834 963695..964111 1 NC_012563.1 identified by similarity to SP:Q01257; match to protein family HMM PF01451; arsenate reductase family protein 964111 7765834 CLM_0903 Clostridium botulinum A2 str. Kyoto arsenate reductase family protein YP_002803133.1 963695 D 536232 CDS YP_002803134.1 226948043 7766480 complement(964341..964787) 1 NC_012563.1 identified by match to protein family HMM PF09719; match to protein family HMM TIGR01909; C_GCAxxG_C_C family protein 964787 7766480 CLM_0904 Clostridium botulinum A2 str. Kyoto C_GCAxxG_C_C family protein YP_002803134.1 964341 R 536232 CDS YP_002803135.1 226948044 7767524 965230..965553 1 NC_012563.1 identified by similarity to SP:Q01256; match to protein family HMM PF01022; putative arsenical resistance operon repressor ArsR 965553 7767524 CLM_0905 Clostridium botulinum A2 str. Kyoto putative arsenical resistance operon repressor ArsR YP_002803135.1 965230 D 536232 CDS YP_002803136.1 226948045 7765560 965574..965945 1 NC_012563.1 identified by match to protein family HMM PF06953; arsenical resistence operon repressor ArsD 965945 arsD 7765560 arsD Clostridium botulinum A2 str. Kyoto arsenical resistence operon repressor ArsD YP_002803136.1 965574 D 536232 CDS YP_002803137.1 226948046 7767685 965964..967709 1 NC_012563.1 identified by similarity to SP:P08690; match to protein family HMM PF02374; match to protein family HMM TIGR00345; putative arsenite-transporting ATPase ArsA 967709 7767685 CLM_0907 Clostridium botulinum A2 str. Kyoto putative arsenite-transporting ATPase ArsA YP_002803137.1 965964 D 536232 CDS YP_002803138.1 226948047 7766361 967804..968217 1 NC_012563.1 identified by match to protein family HMM PF01451; arsenate reductase ArsC 968217 7766361 CLM_0908 Clostridium botulinum A2 str. Kyoto arsenate reductase ArsC YP_002803138.1 967804 D 536232 CDS YP_002803139.1 226948048 7765457 968261..969331 1 NC_012563.1 identified by match to protein family HMM PF01758; match to protein family HMM TIGR00832; arsenical-resistance protein 969331 arsB 7765457 arsB Clostridium botulinum A2 str. Kyoto arsenical-resistance protein YP_002803139.1 968261 D 536232 CDS YP_002803140.1 226948049 7765105 969385..969588 1 NC_012563.1 hypothetical protein 969588 7765105 CLM_0910 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803140.1 969385 D 536232 CDS YP_002803141.1 226948050 7767246 969955..970608 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF08241; match to protein family HMM PF08242; methyltransferase family protein 970608 7767246 CLM_0912 Clostridium botulinum A2 str. Kyoto methyltransferase family protein YP_002803141.1 969955 D 536232 CDS YP_002803142.1 226948051 7765128 complement(970596..970793) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 970793 7765128 CLM_0911 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803142.1 970596 R 536232 CDS YP_002803143.1 226948052 7766026 971212..971760 1 NC_012563.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein 971760 7766026 CLM_0913 Clostridium botulinum A2 str. Kyoto phosphoglycerate mutase family protein YP_002803143.1 971212 D 536232 CDS YP_002803144.1 226948053 7764579 972166..972699 1 NC_012563.1 hypothetical protein 972699 7764579 CLM_0914 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803144.1 972166 D 536232 CDS YP_002803145.1 226948054 7766895 973331..974266 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 974266 7766895 CLM_0915 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803145.1 973331 D 536232 CDS YP_002803146.1 226948055 7766581 974259..975395 1 NC_012563.1 hypothetical protein 975395 7766581 CLM_0916 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803146.1 974259 D 536232 CDS YP_002803147.1 226948056 7765662 975849..976310 1 NC_012563.1 hypothetical protein 976310 7765662 CLM_0917 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803147.1 975849 D 536232 CDS YP_002803148.1 226948057 7767471 976300..977274 1 NC_012563.1 identified by match to protein family HMM PF00303; thymidylate synthase 977274 thyA 7767471 thyA Clostridium botulinum A2 str. Kyoto thymidylate synthase YP_002803148.1 976300 D 536232 CDS YP_002803149.1 226948058 7766620 977286..978044 1 NC_012563.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242; UbiE/COQ5 family methyltransferase 978044 7766620 CLM_0919 Clostridium botulinum A2 str. Kyoto UbiE/COQ5 family methyltransferase YP_002803149.1 977286 D 536232 CDS YP_002803150.1 226948059 7767088 978090..979304 1 NC_012563.1 identified by similarity to SP:P45741; match to protein family HMM PF01547; putative thiamine pyridinylase I 979304 7767088 CLM_0920 Clostridium botulinum A2 str. Kyoto putative thiamine pyridinylase I YP_002803150.1 978090 D 536232 CDS YP_002803151.1 226948060 7764366 979382..980209 1 NC_012563.1 identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097; phosphomethylpyrimidine kinase 980209 thiD 7764366 thiD Clostridium botulinum A2 str. Kyoto phosphomethylpyrimidine kinase YP_002803151.1 979382 D 536232 CDS YP_002803152.1 226948061 7767981 980381..980614 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 980614 7767981 CLM_0922 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803152.1 980381 D 536232 CDS YP_002803153.1 226948062 7766764 complement(980827..981291) 1 NC_012563.1 identified by match to protein family HMM PF06695; putative transporter 981291 7766764 CLM_0923 Clostridium botulinum A2 str. Kyoto putative transporter YP_002803153.1 980827 R 536232 CDS YP_002803154.1 226948063 7766217 981687..982475 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 982475 7766217 CLM_0924 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803154.1 981687 D 536232 CDS YP_002803155.1 226948064 7765096 982478..984145 1 NC_012563.1 ABC transporter permease 984145 7765096 CLM_0925 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002803155.1 982478 D 536232 CDS YP_002803156.1 226948065 7764891 984315..985007 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 985007 7764891 CLM_0926 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002803156.1 984315 D 536232 CDS YP_002803157.1 226948066 7765761 985172..986092 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 986092 7765761 CLM_0927 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803157.1 985172 D 536232 CDS YP_002803158.1 226948067 7764908 986092..986883 1 NC_012563.1 hypothetical protein 986883 7764908 CLM_0928 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803158.1 986092 D 536232 CDS YP_002803159.1 226948068 7767973 987134..987991 1 NC_012563.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445; AraC family transcriptional regulator 987991 7767973 CLM_0929 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002803159.1 987134 D 536232 CDS YP_002803160.1 226948069 7767055 988371..989276 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 989276 7767055 CLM_0930 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803160.1 988371 D 536232 CDS YP_002803161.1 226948070 7765404 990077..991105 1 NC_012563.1 hypothetical protein 991105 7765404 CLM_0931 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803161.1 990077 D 536232 CDS YP_002803162.1 226948071 7764334 991374..992399 1 NC_012563.1 hypothetical protein 992399 7764334 CLM_0932 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803162.1 991374 D 536232 CDS YP_002803163.1 226948072 7767406 992583..993275 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 993275 7767406 CLM_0933 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803163.1 992583 D 536232 CDS YP_002803164.1 226948073 7766474 993262..995958 1 NC_012563.1 identified by match to protein family HMM PF02687; putative ABC transporter permease 995958 7766474 CLM_0934 Clostridium botulinum A2 str. Kyoto putative ABC transporter permease YP_002803164.1 993262 D 536232 CDS YP_002803165.1 226948074 7764309 996171..996290 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 996290 7764309 CLM_0935 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803165.1 996171 D 536232 CDS YP_002803166.1 226948075 7765160 996521..997234 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 997234 7765160 CLM_0936 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002803166.1 996521 D 536232 CDS YP_002803167.1 226948076 7768006 997406..998668 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 998668 7768006 CLM_0937 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803167.1 997406 D 536232 CDS YP_002803168.1 226948077 7766384 998858..999499 1 NC_012563.1 identified by match to protein family HMM PF06555; hypothetical protein 999499 7766384 CLM_0938 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803168.1 998858 D 536232 CDS YP_002803169.1 226948078 7765278 complement(999783..999971) 1 NC_012563.1 identified by match to protein family HMM TIGR02861; small acid-soluble spore protein, H-type 999971 7765278 CLM_0939 Clostridium botulinum A2 str. Kyoto small acid-soluble spore protein, H-type YP_002803169.1 999783 R 536232 CDS YP_002803170.1 226948079 7764627 1000301..1001080 1 NC_012563.1 hypothetical protein 1001080 7764627 CLM_0940 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803170.1 1000301 D 536232 CDS YP_002803171.1 226948080 7767071 1001545..1001673 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1001673 7767071 CLM_0941 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803171.1 1001545 D 536232 CDS YP_002803172.1 226948081 7765730 1001768..1002565 1 NC_012563.1 identified by match to protein family HMM PF01113; match to protein family HMM PF05173; match to protein family HMM TIGR00036; dihydrodipicolinate reductase 1002565 dapB 7765730 dapB Clostridium botulinum A2 str. Kyoto dihydrodipicolinate reductase YP_002803172.1 1001768 D 536232 CDS YP_002803173.1 226948082 7766360 1002587..1003426 1 NC_012563.1 identified by match to protein family HMM PF00581; rhodanese domain-containing protein 1003426 7766360 CLM_0943 Clostridium botulinum A2 str. Kyoto rhodanese domain-containing protein YP_002803173.1 1002587 D 536232 CDS YP_002803174.1 226948083 7764701 1005737..1006066 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1006066 7764701 CLM_0946 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803174.1 1005737 D 536232 CDS YP_002803175.1 226948084 7764914 1006146..1007594 1 NC_012563.1 identified by match to protein family HMM PF00144; beta-lactamase 1007594 7764914 CLM_0947 Clostridium botulinum A2 str. Kyoto beta-lactamase YP_002803175.1 1006146 D 536232 CDS YP_002803176.1 226948085 7765722 1007787..1008392 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 1008392 7765722 CLM_0948 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002803176.1 1007787 D 536232 CDS YP_002803177.1 226948086 7767146 complement(1008584..1009000) 1 NC_012563.1 identified by match to protein family HMM PF00589; phage integrase 1009000 7767146 CLM_0949 Clostridium botulinum A2 str. Kyoto phage integrase YP_002803177.1 1008584 R 536232 CDS YP_002803178.1 226948087 7767996 1009069..1009491 1 NC_012563.1 identified by match to protein family HMM PF00903; glyoxalase family protein 1009491 7767996 CLM_0950 Clostridium botulinum A2 str. Kyoto glyoxalase family protein YP_002803178.1 1009069 D 536232 CDS YP_002803179.1 226948088 7765260 1009607..1009972 1 NC_012563.1 hypothetical protein 1009972 7765260 CLM_0951 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803179.1 1009607 D 536232 CDS YP_002803180.1 226948089 7766240 1010394..1011800 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1011800 7766240 CLM_0952 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803180.1 1010394 D 536232 CDS YP_002803181.1 226948090 7767360 1012136..1013305 1 NC_012563.1 identified by match to protein family HMM PF01979; putative amidohydrolase 1013305 7767360 CLM_0953 Clostridium botulinum A2 str. Kyoto putative amidohydrolase YP_002803181.1 1012136 D 536232 CDS YP_002803182.1 226948091 7764547 1013871..1015172 1 NC_012563.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 1015172 brnQ 7764547 brnQ Clostridium botulinum A2 str. Kyoto branched-chain amino acid transport system II carrier protein YP_002803182.1 1013871 D 536232 CDS YP_002803183.1 226948092 7764432 1015323..1016639 1 NC_012563.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 1016639 brnQ 7764432 brnQ Clostridium botulinum A2 str. Kyoto branched-chain amino acid transport system II carrier protein YP_002803183.1 1015323 D 536232 CDS YP_002803184.1 226948093 7767604 complement(1016718..1019198) 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00496; methyl-accepting chemotaxis protein/ family 5 extracellular solute-binding protein 1019198 7767604 CLM_0956 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein/ family 5 extracellular solute-binding protein YP_002803184.1 1016718 R 536232 CDS YP_002803185.1 226948094 7765135 1019421..1019657 1 NC_012563.1 identified by match to protein family HMM PF04023; feoA family protein 1019657 7765135 CLM_0957 Clostridium botulinum A2 str. Kyoto feoA family protein YP_002803185.1 1019421 D 536232 CDS YP_002803186.1 226948095 7765975 1019802..1020584 1 NC_012563.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231; ferrous iron transport protein B 1020584 feoB 7765975 feoB Clostridium botulinum A2 str. Kyoto ferrous iron transport protein B YP_002803186.1 1019802 D 536232 CDS YP_002803187.1 226948096 7765598 1020581..1022104 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02421; match to protein family HMM PF07664; match to protein family HMM PF07670; ferrous iron transport protein B 1022104 7765598 CLM_0959 Clostridium botulinum A2 str. Kyoto ferrous iron transport protein B YP_002803187.1 1020581 D 536232 CDS YP_002803188.1 226948097 7766250 1022819..1023433 1 NC_012563.1 identified by match to protein family HMM PF00300; match to protein family HMM TIGR03162; alpha-ribazole phosphatase 1023433 cobC 7766250 cobC Clostridium botulinum A2 str. Kyoto alpha-ribazole phosphatase YP_002803188.1 1022819 D 536232 CDS YP_002803189.1 226948098 7764810 1023578..1025140 1 NC_012563.1 identified by match to protein family HMM PF04294; match to protein family HMM PF07501; vanW family protein 1025140 7764810 CLM_0962 Clostridium botulinum A2 str. Kyoto vanW family protein YP_002803189.1 1023578 D 536232 CDS YP_002803190.1 226948099 7764501 1025541..1026287 1 NC_012563.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 1026287 cobS 7764501 cobS Clostridium botulinum A2 str. Kyoto cobalamin synthase YP_002803190.1 1025541 D 536232 CDS YP_002803191.1 226948100 7766018 1026746..1027531 1 NC_012563.1 hypothetical protein 1027531 7766018 CLM_0964 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803191.1 1026746 D 536232 CDS YP_002803192.1 226948101 7765104 1027840..1028121 1 NC_012563.1 hypothetical protein 1028121 7765104 CLM_0965 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803192.1 1027840 D 536232 CDS YP_002803193.1 226948102 7764569 1028252..1028434 1 NC_012563.1 hypothetical protein 1028434 7764569 CLM_0966 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803193.1 1028252 D 536232 CDS YP_002803194.1 226948103 7766094 1028452..1028700 1 NC_012563.1 identified by match to protein family HMM PF07875; hypothetical protein 1028700 7766094 CLM_0967 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803194.1 1028452 D 536232 CDS YP_002803195.1 226948104 7767299 1029269..1030621 1 NC_012563.1 hypothetical protein 1030621 7767299 CLM_0968 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803195.1 1029269 D 536232 CDS YP_002803196.1 226948105 7764683 1030890..1031243 1 NC_012563.1 identified by match to protein family HMM PF01242; match to protein family HMM TIGR03367; queuosine biosynthesis protein QueD 1031243 queD 7764683 queD Clostridium botulinum A2 str. Kyoto queuosine biosynthesis protein QueD YP_002803196.1 1030890 D 536232 CDS YP_002803197.1 226948106 7766756 1031347..1032534 1 NC_012563.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 1032534 folP 7766756 folP Clostridium botulinum A2 str. Kyoto dihydropteroate synthase YP_002803197.1 1031347 D 536232 CDS YP_002803198.1 226948107 7767739 1032687..1032938 1 NC_012563.1 hypothetical protein 1032938 7767739 CLM_0972 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803198.1 1032687 D 536232 CDS YP_002803199.1 226948108 7767939 1033039..1033494 1 NC_012563.1 identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 1033494 folK 7767939 folK Clostridium botulinum A2 str. Kyoto 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase YP_002803199.1 1033039 D 536232 CDS YP_002803200.1 226948109 7764772 1033608..1034048 1 NC_012563.1 identified by match to protein family HMM PF00011; heat shock protein 1034048 7764772 CLM_0974 Clostridium botulinum A2 str. Kyoto heat shock protein YP_002803200.1 1033608 D 536232 CDS YP_002803201.1 226948110 7765183 1034368..1035657 1 NC_012563.1 identified by match to protein family HMM PF00376; match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242; MerR family transcriptional regulator/methyltransferase 1035657 7765183 CLM_0975 Clostridium botulinum A2 str. Kyoto MerR family transcriptional regulator/methyltransferase YP_002803201.1 1034368 D 536232 CDS YP_002803202.1 226948111 7766310 1035712..1036887 1 NC_012563.1 identified by match to protein family HMM PF01041; exopolysaccharide biosynthesis protein 1036887 7766310 CLM_0976 Clostridium botulinum A2 str. Kyoto exopolysaccharide biosynthesis protein YP_002803202.1 1035712 D 536232 CDS YP_002803203.1 226948112 7765721 1037216..1038337 1 NC_012563.1 identified by match to protein family HMM PF01041; putative pleiotropic regulatory protein 1038337 7765721 CLM_0977 Clostridium botulinum A2 str. Kyoto putative pleiotropic regulatory protein YP_002803203.1 1037216 D 536232 CDS YP_002803204.1 226948113 7767625 1039152..1039346 1 NC_012563.1 hypothetical protein 1039346 7767625 CLM_0978 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803204.1 1039152 D 536232 CDS YP_002803205.1 226948114 7764733 1039787..1040299 1 NC_012563.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; match to protein family HMM TIGR02954; ECF family RNA polymerase sigma-70 factor 1040299 7764733 CLM_0979 Clostridium botulinum A2 str. Kyoto ECF family RNA polymerase sigma-70 factor YP_002803205.1 1039787 D 536232 CDS YP_002803206.1 226948115 7765821 1040304..1041467 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1041467 7765821 CLM_0980 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803206.1 1040304 D 536232 CDS YP_002803207.1 226948116 7765882 complement(1041759..1042313) 1 NC_012563.1 putative flavoredoxin 1042313 7765882 CLM_0981 Clostridium botulinum A2 str. Kyoto putative flavoredoxin YP_002803207.1 1041759 R 536232 CDS YP_002803208.1 226948117 7767534 1042798..1043292 1 NC_012563.1 identified by similarity to GB:CAA50581.1; match to protein family HMM PF01243; nitroimidazole resistance protein NimA 1043292 nimA 7767534 nimA Clostridium botulinum A2 str. Kyoto nitroimidazole resistance protein NimA YP_002803208.1 1042798 D 536232 CDS YP_002803209.1 226948118 7764214 complement(1043747..1044541) 1 NC_012563.1 putative ABC transporter permease 1044541 7764214 CLM_0983 Clostridium botulinum A2 str. Kyoto putative ABC transporter permease YP_002803209.1 1043747 R 536232 CDS YP_002803210.1 226948119 7765288 complement(1044560..1045477) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1045477 7765288 CLM_0984 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803210.1 1044560 R 536232 CDS YP_002803211.1 226948120 7766862 complement(1045449..1046603) 1 NC_012563.1 identified by match to protein family HMM PF01381; HTH domain-containing protein 1046603 7766862 CLM_0986 Clostridium botulinum A2 str. Kyoto HTH domain-containing protein YP_002803211.1 1045449 R 536232 CDS YP_002803212.1 226948121 7764327 1047245..1047373 1 NC_012563.1 hypothetical protein 1047373 7764327 CLM_0987 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803212.1 1047245 D 536232 CDS YP_002803213.1 226948122 7765009 1048058..1048870 1 NC_012563.1 identified by match to protein family HMM PF00561; non-heme haloperoxidase family protein 1048870 7765009 CLM_0988 Clostridium botulinum A2 str. Kyoto non-heme haloperoxidase family protein YP_002803213.1 1048058 D 536232 CDS YP_002803214.1 226948123 7765609 1049990..1050643 1 NC_012563.1 identified by match to protein family HMM PF00805; pentapeptide repeat family protein 1050643 7765609 CLM_0991 Clostridium botulinum A2 str. Kyoto pentapeptide repeat family protein YP_002803214.1 1049990 D 536232 CDS YP_002803215.1 226948124 7766670 complement(1050913..1051482) 1 NC_012563.1 identified by match to protein family HMM PF02525; flavodoxin-like fold domain-containing protein 1051482 7766670 CLM_0992 Clostridium botulinum A2 str. Kyoto flavodoxin-like fold domain-containing protein YP_002803215.1 1050913 R 536232 CDS YP_002803216.1 226948125 7767847 complement(1051500..1052054) 1 NC_012563.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358; flavin reductase 1052054 7767847 CLM_0993 Clostridium botulinum A2 str. Kyoto flavin reductase YP_002803216.1 1051500 R 536232 CDS YP_002803217.1 226948126 7764961 complement(1052159..1052485) 1 NC_012563.1 ArsR family transcriptional regulator 1052485 7764961 CLM_0994 Clostridium botulinum A2 str. Kyoto ArsR family transcriptional regulator YP_002803217.1 1052159 R 536232 CDS YP_002803218.1 226948127 7765394 complement(1052829..1053656) 1 NC_012563.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 1053656 7765394 CLM_0995 Clostridium botulinum A2 str. Kyoto MerR family transcriptional regulator YP_002803218.1 1052829 R 536232 CDS YP_002803219.1 226948128 7766088 1053768..1054385 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1054385 7766088 CLM_0996 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803219.1 1053768 D 536232 CDS YP_002803220.1 226948129 7767356 1054591..1055106 1 NC_012563.1 identified by match to protein family HMM PF04229; hypothetical protein 1055106 7767356 CLM_0997 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803220.1 1054591 D 536232 CDS YP_002803221.1 226948130 7764362 1055169..1055693 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1055693 7764362 CLM_0998 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803221.1 1055169 D 536232 CDS YP_002803222.1 226948131 7767237 complement(1056399..1057100) 1 NC_012563.1 identified by match to protein family HMM PF02678; hypothetical protein 1057100 7767237 CLM_0999 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803222.1 1056399 R 536232 CDS YP_002803223.1 226948132 7767450 complement(1057377..1057685) 1 NC_012563.1 identified by match to protein family HMM PF01638; putative transcriptional regulator 1057685 7767450 CLM_1000 Clostridium botulinum A2 str. Kyoto putative transcriptional regulator YP_002803223.1 1057377 R 536232 CDS YP_002803224.1 226948133 7766627 1057813..1058442 1 NC_012563.1 identified by match to protein family HMM PF00881; nitroreductase family protein 1058442 7766627 CLM_1001 Clostridium botulinum A2 str. Kyoto nitroreductase family protein YP_002803224.1 1057813 D 536232 CDS YP_002803225.1 226948134 7766171 1058806..1060248 1 NC_012563.1 identified by similarity to GB:AAF40217.1; triacylglycerol lipase 1060248 lipA 7766171 lipA Clostridium botulinum A2 str. Kyoto triacylglycerol lipase YP_002803225.1 1058806 D 536232 CDS YP_002803226.1 226948135 7765606 complement(1060406..1061614) 1 NC_012563.1 identified by match to protein family HMM PF00190; match to protein family HMM PF07883; match to protein family HMM TIGR03404; oxalate decarboxylase 1061614 oxdD 7765606 oxdD Clostridium botulinum A2 str. Kyoto oxalate decarboxylase YP_002803226.1 1060406 R 536232 CDS YP_002803227.1 226948136 7764479 complement(1061872..1062450) 1 NC_012563.1 identified by match to protein family HMM PF03641; match to protein family HMM TIGR00730; decarboxylase family protein 1062450 7764479 CLM_1004 Clostridium botulinum A2 str. Kyoto decarboxylase family protein YP_002803227.1 1061872 R 536232 CDS YP_002803228.1 226948137 7766789 complement(1062508..1062963) 1 NC_012563.1 identified by match to protein family HMM PF04657; hypothetical protein 1062963 7766789 CLM_1005 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803228.1 1062508 R 536232 CDS YP_002803229.1 226948138 7765248 1063077..1063964 1 NC_012563.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1063964 7765248 CLM_1006 Clostridium botulinum A2 str. Kyoto LysR family transcriptional regulator YP_002803229.1 1063077 D 536232 CDS YP_002803230.1 226948139 7764399 1064236..1064682 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1064682 7764399 CLM_1007 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803230.1 1064236 D 536232 CDS YP_002803231.1 226948140 7766991 complement(1064977..1065447) 1 NC_012563.1 hypothetical protein 1065447 7766991 CLM_1008 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803231.1 1064977 R 536232 CDS YP_002803232.1 226948141 7765717 complement(1065447..1066208) 1 NC_012563.1 identified by match to protein family HMM PF06738; hypothetical protein 1066208 7765717 CLM_1009 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803232.1 1065447 R 536232 CDS YP_002803233.1 226948142 7767824 complement(1066869..1067369) 1 NC_012563.1 identified by match to protein family HMM PF01327; putative peptide deformylase 1067369 7767824 CLM_1010 Clostridium botulinum A2 str. Kyoto putative peptide deformylase YP_002803233.1 1066869 R 536232 CDS YP_002803234.1 226948143 7765012 1067603..1069039 1 NC_012563.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 1069039 7765012 CLM_1011 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002803234.1 1067603 D 536232 CDS YP_002803235.1 226948144 7765621 complement(1069117..1069635) 1 NC_012563.1 identified by match to protein family HMM PF00881; nitroreductase family protein 1069635 7765621 CLM_1012 Clostridium botulinum A2 str. Kyoto nitroreductase family protein YP_002803235.1 1069117 R 536232 CDS YP_002803236.1 226948145 7766827 1069820..1069936 1 NC_012563.1 MarR family transcriptional regulator 1069936 7766827 CLM_1013 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002803236.1 1069820 D 536232 CDS YP_002803237.1 226948146 7766448 complement(1069937..1070743) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; iron-sulfur cluster-binding protein 1070743 7766448 CLM_1014 Clostridium botulinum A2 str. Kyoto iron-sulfur cluster-binding protein YP_002803237.1 1069937 R 536232 CDS YP_002803238.1 226948147 7767612 1071090..1071251 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1071251 7767612 CLM_1015 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803238.1 1071090 D 536232 CDS YP_002803239.1 226948148 7764246 1071482..1072186 1 NC_012563.1 alpha/beta hydrolase 1072186 7764246 CLM_1016 Clostridium botulinum A2 str. Kyoto alpha/beta hydrolase YP_002803239.1 1071482 D 536232 CDS YP_002803240.1 226948149 7765308 1072149..1073387 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 1073387 7765308 CLM_1017 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002803240.1 1072149 D 536232 CDS YP_002803241.1 226948150 7766618 1074982..1076871 1 NC_012563.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00830; match to protein family HMM TIGR01995; PTS system beta-glucoside-specific transporter subunit IIABC 1076871 7766618 CLM_1020 Clostridium botulinum A2 str. Kyoto PTS system beta-glucoside-specific transporter subunit IIABC YP_002803241.1 1074982 D 536232 CDS YP_002803242.1 226948151 7767572 1077200..1078621 1 NC_012563.1 identified by match to protein family HMM PF00232; glycosyl hydrolase, family 1 1078621 7767572 CLM_1021 Clostridium botulinum A2 str. Kyoto glycosyl hydrolase, family 1 YP_002803242.1 1077200 D 536232 CDS YP_002803243.1 226948152 7764298 1078749..1078955 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1078955 7764298 CLM_1022 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803243.1 1078749 D 536232 CDS YP_002803244.1 226948153 7765294 complement(1079157..1080110) 1 NC_012563.1 identified by match to protein family HMM PF00953; phospho-N-acetylmuramoyl-pentapeptide- transferase 1080110 mraY 7765294 mraY Clostridium botulinum A2 str. Kyoto phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002803244.1 1079157 R 536232 CDS YP_002803245.1 226948154 7766994 complement(1080206..1080337) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1080337 7766994 CLM_1024 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803245.1 1080206 R 536232 CDS YP_002803246.1 226948155 7766032 1080538..1081398 1 NC_012563.1 identified by match to protein family HMM PF01381; putative DNA-binding protein 1081398 7766032 CLM_1025 Clostridium botulinum A2 str. Kyoto putative DNA-binding protein YP_002803246.1 1080538 D 536232 CDS YP_002803247.1 226948156 7765111 1081823..1082473 1 NC_012563.1 identified by match to protein family HMM PF00132; chloramphenicol acetyltransferase 1082473 7765111 CLM_1026 Clostridium botulinum A2 str. Kyoto chloramphenicol acetyltransferase YP_002803247.1 1081823 D 536232 CDS YP_002803248.1 226948157 7764869 1083899..1084645 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 1084645 7764869 CLM_1029 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002803248.1 1083899 D 536232 CDS YP_002803249.1 226948158 7765196 complement(1084781..1086013) 1 NC_012563.1 identified by match to protein family HMM PF04371; peptidyl-arginine deiminase 1086013 7765196 CLM_1030 Clostridium botulinum A2 str. Kyoto peptidyl-arginine deiminase YP_002803249.1 1084781 R 536232 CDS YP_002803250.1 226948159 7768013 1087090..1087242 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; multimeric flavodoxin WrbA family protein 1087242 7768013 CLM_1033 Clostridium botulinum A2 str. Kyoto multimeric flavodoxin WrbA family protein YP_002803250.1 1087090 D 536232 CDS YP_002803251.1 226948160 7765205 1087275..1087427 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1087427 7765205 CLM_1034 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803251.1 1087275 D 536232 CDS YP_002803252.1 226948161 7765736 1087717..1087839 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1087839 7765736 CLM_1035 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803252.1 1087717 D 536232 CDS YP_002803253.1 226948162 7767138 complement(1088169..1088555) 1 NC_012563.1 hypothetical protein 1088555 7767138 CLM_1036 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803253.1 1088169 R 536232 CDS YP_002803254.1 226948163 7767374 1089303..1089779 1 NC_012563.1 identified by match to protein family HMM PF09557; match to protein family HMM TIGR02271; hypothetical protein 1089779 7767374 CLM_1037 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803254.1 1089303 D 536232 CDS YP_002803255.1 226948164 7766068 1089858..1090526 1 NC_012563.1 identified by match to protein family HMM PF09557; match to protein family HMM TIGR02271; hypothetical protein 1090526 7766068 CLM_1038 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803255.1 1089858 D 536232 CDS YP_002803256.1 226948165 7765639 1090939..1091529 1 NC_012563.1 identified by match to protein family HMM PF04229; hypothetical protein 1091529 7765639 CLM_1039 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803256.1 1090939 D 536232 CDS YP_002803257.1 226948166 7764468 complement(1091610..1091987) 1 NC_012563.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 1091987 7764468 CLM_1040 Clostridium botulinum A2 str. Kyoto ErfK/YbiS/YcfS/YnhG family protein YP_002803257.1 1091610 R 536232 CDS YP_002803258.1 226948167 7765068 complement(1092163..1092513) 1 NC_012563.1 hypothetical protein 1092513 7765068 CLM_1041 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803258.1 1092163 R 536232 CDS YP_002803259.1 226948168 7765684 1092608..1092730 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1092730 7765684 CLM_1042 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803259.1 1092608 D 536232 CDS YP_002803260.1 226948169 7766209 complement(1092777..1093085) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer; putative; hypothetical protein 1093085 7766209 CLM_1043 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803260.1 1092777 R 536232 CDS YP_002803261.1 226948170 7767991 complement(1093303..1093680) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; acetyltransferase 1093680 7767991 CLM_1044 Clostridium botulinum A2 str. Kyoto acetyltransferase YP_002803261.1 1093303 R 536232 CDS YP_002803262.1 226948171 7764491 complement(1093696..1093830) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; GCN5-related N-acetyltransferase 1093830 7764491 CLM_1045 Clostridium botulinum A2 str. Kyoto GCN5-related N-acetyltransferase YP_002803262.1 1093696 R 536232 CDS YP_002803263.1 226948172 7765241 1094207..1094977 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1094977 7765241 CLM_1046 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803263.1 1094207 D 536232 CDS YP_002803264.1 226948173 7766236 1095517..1097124 1 NC_012563.1 hypothetical protein 1097124 7766236 CLM_1047 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803264.1 1095517 D 536232 CDS YP_002803265.1 226948174 7767623 complement(1097487..1099847) 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF02687; ABC transporter ATP-binding protein/permease 1099847 7767623 CLM_1048 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein/permease YP_002803265.1 1097487 R 536232 CDS YP_002803266.1 226948175 7764552 1100006..1100677 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 1100677 7764552 CLM_1049 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002803266.1 1100006 D 536232 CDS YP_002803267.1 226948176 7765846 1100677..1101705 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 1101705 7765846 CLM_1050 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803267.1 1100677 D 536232 CDS YP_002803268.1 226948177 7766468 1102115..1103140 1 NC_012563.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1103140 ilvE 7766468 ilvE Clostridium botulinum A2 str. Kyoto branched-chain amino acid aminotransferase YP_002803268.1 1102115 D 536232 CDS YP_002803269.1 226948178 7767560 1103380..1103925 1 NC_012563.1 identified by match to protein family HMM PF02632; BioY family protein 1103925 7767560 CLM_1052 Clostridium botulinum A2 str. Kyoto BioY family protein YP_002803269.1 1103380 D 536232 CDS YP_002803270.1 226948179 7764427 1104154..1104801 1 NC_012563.1 identified by match to protein family HMM PF04199; cyclase family protein 1104801 7764427 CLM_1053 Clostridium botulinum A2 str. Kyoto cyclase family protein YP_002803270.1 1104154 D 536232 CDS YP_002803271.1 226948180 7765043 1105188..1105733 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1105733 7765043 CLM_1054 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803271.1 1105188 D 536232 CDS YP_002803272.1 226948181 7765428 1105805..1107400 1 NC_012563.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR00498; putative LexA repressor 1107400 7765428 CLM_1055 Clostridium botulinum A2 str. Kyoto putative LexA repressor YP_002803272.1 1105805 D 536232 CDS YP_002803273.1 226948182 7766831 1107692..1108249 1 NC_012563.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 1108249 cobU 7766831 cobU Clostridium botulinum A2 str. Kyoto adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase YP_002803273.1 1107692 D 536232 CDS YP_002803274.1 226948183 7765924 1108576..1109457 1 NC_012563.1 hypothetical protein 1109457 7765924 CLM_1057 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803274.1 1108576 D 536232 CDS YP_002803275.1 226948184 7766294 complement(1109563..1110330) 1 NC_012563.1 identified by similarity to SP:P0A4T9; match to protein family HMM PF00376; match to protein family HMM PF07739; transcriptional activator TipA 1110330 tipA 7766294 tipA Clostridium botulinum A2 str. Kyoto transcriptional activator TipA YP_002803275.1 1109563 R 536232 CDS YP_002803276.1 226948185 7767286 1110843..1110974 1 NC_012563.1 hypothetical protein 1110974 7767286 CLM_1060 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803276.1 1110843 D 536232 CDS YP_002803277.1 226948186 7767439 1111035..1112516 1 NC_012563.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase 1112516 cobQ 7767439 cobQ Clostridium botulinum A2 str. Kyoto cobyric acid synthase YP_002803277.1 1111035 D 536232 CDS YP_002803278.1 226948187 7764795 1112518..1113489 1 NC_012563.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein 1113489 cobD 7764795 cobD Clostridium botulinum A2 str. Kyoto cobalamin biosynthesis protein YP_002803278.1 1112518 D 536232 CDS YP_002803279.1 226948188 7766139 1113874..1114962 1 NC_012563.1 identified by match to protein family HMM PF00155; aminotransferase family protein 1114962 7766139 CLM_1063 Clostridium botulinum A2 str. Kyoto aminotransferase family protein YP_002803279.1 1113874 D 536232 CDS YP_002803280.1 226948189 7767022 1115147..1115866 1 NC_012563.1 catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 1115866 cbiM 7767022 cbiM Clostridium botulinum A2 str. Kyoto cobalt transport protein CbiM YP_002803280.1 1115147 D 536232 CDS YP_002803281.1 226948190 7766364 1115870..1116169 1 NC_012563.1 identified by match to protein family HMM PF02553; match to protein family HMM TIGR01165; cobalt transport protein 1116169 cbiN 7766364 cbiN Clostridium botulinum A2 str. Kyoto cobalt transport protein YP_002803281.1 1115870 D 536232 CDS YP_002803282.1 226948191 7767268 1116147..1116830 1 NC_012563.1 identified by match to protein family HMM PF02361; match to protein family HMM TIGR02454; cobalt ABC transporter permease CbiQ 1116830 cbiQ 7767268 cbiQ Clostridium botulinum A2 str. Kyoto cobalt ABC transporter permease CbiQ YP_002803282.1 1116147 D 536232 CDS YP_002803283.1 226948192 7764263 1117179..1117826 1 NC_012563.1 catalyzes the formation of siroheme from precorrin-2; precorrin-2 dehydrogenase 1117826 7764263 CLM_1067 Clostridium botulinum A2 str. Kyoto precorrin-2 dehydrogenase YP_002803283.1 1117179 D 536232 CDS YP_002803284.1 226948193 7767655 1117795..1118667 1 NC_012563.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1118667 hemC 7767655 hemC Clostridium botulinum A2 str. Kyoto porphobilinogen deaminase YP_002803284.1 1117795 D 536232 CDS YP_002803285.1 226948194 7764217 1118803..1120263 1 NC_012563.1 identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469; uroporphyrinogen III synthase/methyltransferase 1120263 7764217 CLM_1069 Clostridium botulinum A2 str. Kyoto uroporphyrinogen III synthase/methyltransferase YP_002803285.1 1118803 D 536232 CDS YP_002803286.1 226948195 7765794 1120408..1120590 1 NC_012563.1 hypothetical protein 1120590 7765794 CLM_1070 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803286.1 1120408 D 536232 CDS YP_002803287.1 226948196 7765385 1120852..1121826 1 NC_012563.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 1121826 hemB 7765385 hemB Clostridium botulinum A2 str. Kyoto delta-aminolevulinic acid dehydratase YP_002803287.1 1120852 D 536232 CDS YP_002803288.1 226948197 7766519 1122059..1123381 1 NC_012563.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 1123381 cobB 7766519 cobB Clostridium botulinum A2 str. Kyoto cobyrinic acid a,c-diamide synthase YP_002803288.1 1122059 D 536232 CDS YP_002803289.1 226948198 7767633 1123406..1124032 1 NC_012563.1 catalyzes the interconversion of precorrin-8X and cobyrinic acid; precorrin-8X methylmutase 1124032 cbiC 7767633 cbiC Clostridium botulinum A2 str. Kyoto precorrin-8X methylmutase YP_002803289.1 1123406 D 536232 CDS YP_002803290.1 226948199 7765151 1124330..1124860 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1124860 7765151 CLM_1074 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803290.1 1124330 D 536232 CDS YP_002803291.1 226948200 7764279 1124920..1125639 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 1125639 7764279 CLM_1075 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803291.1 1124920 D 536232 CDS YP_002803292.1 226948201 7766893 1125938..1126192 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; HD domain-containing protein 1126192 7766893 CLM_1076 Clostridium botulinum A2 str. Kyoto HD domain-containing protein YP_002803292.1 1125938 D 536232 CDS YP_002803293.1 226948202 7767786 1126615..1127379 1 NC_012563.1 identified by match to protein family HMM PF00753; beta-lactamase domain-containing protein 1127379 7767786 CLM_1077 Clostridium botulinum A2 str. Kyoto beta-lactamase domain-containing protein YP_002803293.1 1126615 D 536232 CDS YP_002803294.1 226948203 7766014 1127732..1128466 1 NC_012563.1 transporter 1128466 7766014 CLM_1078 Clostridium botulinum A2 str. Kyoto transporter YP_002803294.1 1127732 D 536232 CDS YP_002803295.1 226948204 7764806 1128518..1128943 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1128943 7764806 CLM_1079 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803295.1 1128518 D 536232 CDS YP_002803296.1 226948205 7766256 1129195..1129896 1 NC_012563.1 identified by match to protein family HMM PF02661; Fic family protein 1129896 7766256 CLM_1080 Clostridium botulinum A2 str. Kyoto Fic family protein YP_002803296.1 1129195 D 536232 CDS YP_002803297.1 226948206 7767391 1129925..1130446 1 NC_012563.1 identified by match to protein family HMM PF00881; nitroreductase family protein 1130446 7767391 CLM_1081 Clostridium botulinum A2 str. Kyoto nitroreductase family protein YP_002803297.1 1129925 D 536232 CDS YP_002803298.1 226948207 7765522 1130516..1130809 1 NC_012563.1 membrane protein 1130809 7765522 CLM_1082 Clostridium botulinum A2 str. Kyoto membrane protein YP_002803298.1 1130516 D 536232 CDS YP_002803299.1 226948208 7767341 1131001..1131495 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF04229; glutamate-rich protein GrpB 1131495 7767341 CLM_1085 Clostridium botulinum A2 str. Kyoto glutamate-rich protein GrpB YP_002803299.1 1131001 D 536232 CDS YP_002803300.1 226948209 7764979 1131508..1132587 1 NC_012563.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase 1132587 cbiD 7764979 cbiD Clostridium botulinum A2 str. Kyoto cobalt-precorrin-6A synthase YP_002803300.1 1131508 D 536232 CDS YP_002803301.1 226948210 7768023 1132787..1133458 1 NC_012563.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; precorrin-6y C5,15-methyltransferase subunit CbiE 1133458 cbiE 7768023 cbiE Clostridium botulinum A2 str. Kyoto precorrin-6y C5,15-methyltransferase subunit CbiE YP_002803301.1 1132787 D 536232 CDS YP_002803302.1 226948211 7767152 1133421..1133540 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1133540 7767152 CLM_1088 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803302.1 1133421 D 536232 CDS YP_002803303.1 226948212 7765300 1133642..1134022 1 NC_012563.1 hypothetical protein 1134022 7765300 CLM_1089 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803303.1 1133642 D 536232 CDS YP_002803304.1 226948213 7767541 1134086..1134667 1 NC_012563.1 identified by match to protein family HMM TIGR01444; match to protein family HMM TIGR02469; precorrin-6y C5,15-methyltransferase subunit CbiT 1134667 cbiT 7767541 cbiT Clostridium botulinum A2 str. Kyoto precorrin-6y C5,15-methyltransferase subunit CbiT YP_002803304.1 1134086 D 536232 CDS YP_002803305.1 226948214 7765758 1134690..1135241 1 NC_012563.1 hypothetical protein 1135241 7765758 CLM_1091 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803305.1 1134690 D 536232 CDS YP_002803306.1 226948215 7764866 1135715..1135906 1 NC_012563.1 hypothetical protein 1135906 7764866 CLM_1092 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803306.1 1135715 D 536232 CDS YP_002803307.1 226948216 7767735 1136064..1136516 1 NC_012563.1 hypothetical protein 1136516 7767735 CLM_1093 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803307.1 1136064 D 536232 CDS YP_002803308.1 226948217 7764249 1136576..1136917 1 NC_012563.1 hypothetical protein 1136917 7764249 CLM_1094 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803308.1 1136576 D 536232 CDS YP_002803309.1 226948218 7765330 1136985..1137533 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1137533 7765330 CLM_1095 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803309.1 1136985 D 536232 CDS YP_002803310.1 226948219 7767370 1137583..1137975 1 NC_012563.1 hypothetical protein 1137975 7767370 CLM_1096 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803310.1 1137583 D 536232 CDS YP_002803311.1 226948220 7764466 1138066..1138782 1 NC_012563.1 catalyzes the formation of precorrin-3A from precorrin-2; cobalt-precorrin-2 C(20)-methyltransferase 1138782 cobI 7764466 cobI Clostridium botulinum A2 str. Kyoto cobalt-precorrin-2 C(20)-methyltransferase YP_002803311.1 1138066 D 536232 CDS YP_002803312.1 226948221 7765655 1139071..1139829 1 NC_012563.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465; precorrin-4 C(11)-methyltransferase 1139829 cobM 7765655 cobM Clostridium botulinum A2 str. Kyoto precorrin-4 C(11)-methyltransferase YP_002803312.1 1139071 D 536232 CDS YP_002803313.1 226948222 7765772 1139807..1140928 1 NC_012563.1 identified by match to protein family HMM PF01890; cobalamin biosynthesis protein CbiG 1140928 cbiG 7765772 cbiG Clostridium botulinum A2 str. Kyoto cobalamin biosynthesis protein CbiG YP_002803313.1 1139807 D 536232 CDS YP_002803314.1 226948223 7765649 1141062..1141793 1 NC_012563.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466; precorrin-3B C(17)-methyltransferase 1141793 cobJ 7765649 cobJ Clostridium botulinum A2 str. Kyoto precorrin-3B C(17)-methyltransferase YP_002803314.1 1141062 D 536232 CDS YP_002803315.1 226948224 7764527 1141970..1142737 1 NC_012563.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase 1142737 cobK 7764527 cobK Clostridium botulinum A2 str. Kyoto cobalt-precorrin-6x reductase YP_002803315.1 1141970 D 536232 CDS YP_002803316.1 226948225 7766688 1142817..1143305 1 NC_012563.1 hypothetical protein 1143305 7766688 CLM_1102 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803316.1 1142817 D 536232 CDS YP_002803317.1 226948226 7765209 1143521..1144303 1 NC_012563.1 identified by match to protein family HMM PF01903; match to protein family HMM PF06180; anaerobic sirohydrochlorin cobaltochelatase 1144303 cbiK 7765209 cbiK Clostridium botulinum A2 str. Kyoto anaerobic sirohydrochlorin cobaltochelatase YP_002803317.1 1143521 D 536232 CDS YP_002803318.1 226948227 7766986 1144316..1145155 1 NC_012563.1 identified by match to protein family HMM PF00288; putative kinase 1145155 7766986 CLM_1104 Clostridium botulinum A2 str. Kyoto putative kinase YP_002803318.1 1144316 D 536232 CDS YP_002803319.1 226948228 7768103 1145282..1145803 1 NC_012563.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1145803 cobO 7768103 cobO Clostridium botulinum A2 str. Kyoto cob(I)yrinic acid a,c-diamide adenosyltransferase YP_002803319.1 1145282 D 536232 CDS YP_002803320.1 226948229 7764789 1146056..1146745 1 NC_012563.1 identified by match to protein family HMM PF00027; match to protein family HMM PF00325; Crp/Fnr family transcriptional regulator 1146745 7764789 CLM_1106 Clostridium botulinum A2 str. Kyoto Crp/Fnr family transcriptional regulator YP_002803320.1 1146056 D 536232 CDS YP_002803321.1 226948230 7767466 1146845..1147609 1 NC_012563.1 identified by match to protein family HMM PF01226; formate/nitrite transporter family protein 1147609 7767466 CLM_1107 Clostridium botulinum A2 str. Kyoto formate/nitrite transporter family protein YP_002803321.1 1146845 D 536232 CDS YP_002803322.1 226948231 7767815 1147629..1148657 1 NC_012563.1 identified by match to protein family HMM TIGR02910; sulfite reductase subunit A 1148657 asrA 7767815 asrA Clostridium botulinum A2 str. Kyoto sulfite reductase subunit A YP_002803322.1 1147629 D 536232 CDS YP_002803323.1 226948232 7764708 1148644..1149441 1 NC_012563.1 with AsrAC catalyzes the reduction of sulfite to hydrogen sulfide; anaerobic sulfite reductase subunit B 1149441 asrB 7764708 asrB Clostridium botulinum A2 str. Kyoto anaerobic sulfite reductase subunit B YP_002803323.1 1148644 D 536232 CDS YP_002803324.1 226948233 7766029 1149454..1150419 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM TIGR02912; anaerobic sulfite reductase subunit C 1150419 arsC 7766029 arsC Clostridium botulinum A2 str. Kyoto anaerobic sulfite reductase subunit C YP_002803324.1 1149454 D 536232 CDS YP_002803325.1 226948234 7766353 1150765..1151787 1 NC_012563.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; molybdopterin biosynthesis protein 1151787 7766353 CLM_1111 Clostridium botulinum A2 str. Kyoto molybdopterin biosynthesis protein YP_002803325.1 1150765 D 536232 CDS YP_002803326.1 226948235 7767206 complement(1152537..1152674) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1152674 7767206 CLM_1112 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803326.1 1152537 R 536232 CDS YP_002803327.1 226948236 7767194 1153103..1154122 1 NC_012563.1 hypothetical protein 1154122 7767194 CLM_1113 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803327.1 1153103 D 536232 CDS YP_002803328.1 226948237 7768076 1154143..1155030 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1155030 7768076 CLM_1114 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803328.1 1154143 D 536232 CDS YP_002803329.1 226948238 7767020 1155034..1155810 1 NC_012563.1 hypothetical protein 1155810 7767020 CLM_1115 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803329.1 1155034 D 536232 CDS YP_002803330.1 226948239 7765909 1156460..1157182 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 1157182 7765909 CLM_1116 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002803330.1 1156460 D 536232 CDS YP_002803331.1 226948240 7764516 1157172..1158593 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 1158593 7764516 CLM_1117 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803331.1 1157172 D 536232 CDS YP_002803332.1 226948241 7767723 complement(1159076..1159846) 1 NC_012563.1 identified by match to protein family HMM PF00005; iron chelate uptake ABC transporter ATP-binding protein 1159846 7767723 CLM_1118 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter ATP-binding protein YP_002803332.1 1159076 R 536232 CDS YP_002803333.1 226948242 7766267 complement(1159847..1160926) 1 NC_012563.1 identified by match to protein family HMM PF00950; match to protein family HMM PF01032; match to protein family HMM PF02653; iron chelate uptake ABC transporter permease 1160926 7766267 CLM_1119 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter permease YP_002803333.1 1159847 R 536232 CDS YP_002803334.1 226948243 7765303 complement(1160927..1161949) 1 NC_012563.1 identified by match to protein family HMM PF01497; putative iron chelate uptake ABC transporter solute-binding protein 1161949 7765303 CLM_1120 Clostridium botulinum A2 str. Kyoto putative iron chelate uptake ABC transporter solute-binding protein YP_002803334.1 1160927 R 536232 CDS YP_002803335.1 226948244 7765994 1162606..1162746 1 NC_012563.1 pentapeptide repeat family protein 1162746 7765994 CLM_1122 Clostridium botulinum A2 str. Kyoto pentapeptide repeat family protein YP_002803335.1 1162606 D 536232 CDS YP_002803336.1 226948245 7767213 complement(1163032..1163724) 1 NC_012563.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254; HAD superfamily hydrolase 1163724 7767213 CLM_1123 Clostridium botulinum A2 str. Kyoto HAD superfamily hydrolase YP_002803336.1 1163032 R 536232 CDS YP_002803337.1 226948246 7766369 complement(1163755..1164045) 1 NC_012563.1 hypothetical protein 1164045 7766369 CLM_1124 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803337.1 1163755 R 536232 CDS YP_002803338.1 226948247 7765345 1164147..1164521 1 NC_012563.1 hypothetical protein 1164521 7765345 CLM_1125 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803338.1 1164147 D 536232 CDS YP_002803339.1 226948248 7764247 complement(1164794..1165672) 1 NC_012563.1 identified by match to protein family HMM PF00126; LysR family transcriptional regulator 1165672 7764247 CLM_1126 Clostridium botulinum A2 str. Kyoto LysR family transcriptional regulator YP_002803339.1 1164794 R 536232 CDS YP_002803340.1 226948249 7765387 1165793..1166911 1 NC_012563.1 identified by match to protein family HMM PF00291; threonine synthase 1166911 7765387 CLM_1127 Clostridium botulinum A2 str. Kyoto threonine synthase YP_002803340.1 1165793 D 536232 CDS YP_002803341.1 226948250 7764288 1167593..1168057 1 NC_012563.1 identified by similarity to GB:CAA50581.1; match to protein family HMM PF01243; putative nitroimidazole resistance protein NimA 1168057 7764288 CLM_1128 Clostridium botulinum A2 str. Kyoto putative nitroimidazole resistance protein NimA YP_002803341.1 1167593 D 536232 CDS YP_002803342.1 226948251 7768037 complement(1168283..1168453) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1168453 7768037 CLM_1129 Clostridium botulinum A2 str. Kyoto transposase YP_002803342.1 1168283 R 536232 CDS YP_002803343.1 226948252 7765868 complement(1169426..1171186) 1 NC_012563.1 in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone; dihydroxyacetone kinase 1171186 dhaKL 7765868 dhaKL Clostridium botulinum A2 str. Kyoto dihydroxyacetone kinase YP_002803343.1 1169426 R 536232 CDS YP_002803344.1 226948253 7764706 complement(1171197..1172327) 1 NC_012563.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 1172327 gldA 7764706 gldA Clostridium botulinum A2 str. Kyoto glycerol dehydrogenase YP_002803344.1 1171197 R 536232 CDS YP_002803345.1 226948254 7764748 complement(1172848..1173885) 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 1173885 7764748 CLM_1133 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002803345.1 1172848 R 536232 CDS YP_002803346.1 226948255 7765696 1174331..1174795 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1174795 7765696 CLM_1134 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803346.1 1174331 D 536232 CDS YP_002803347.1 226948256 7764907 1175002..1175445 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1175445 7764907 CLM_1135 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803347.1 1175002 D 536232 CDS YP_002803348.1 226948257 7765774 1175598..1176191 1 NC_012563.1 identified by match to protein family HMM PF07081; hypothetical protein 1176191 7765774 CLM_1136 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803348.1 1175598 D 536232 CDS YP_002803349.1 226948258 7767131 1176255..1176458 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1176458 7767131 CLM_1137 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803349.1 1176255 D 536232 CDS YP_002803350.1 226948259 7768007 1176576..1177421 1 NC_012563.1 identified by match to protein family HMM PF00248; aldo/keto reductase family oxidoreductase 1177421 7768007 CLM_1138 Clostridium botulinum A2 str. Kyoto aldo/keto reductase family oxidoreductase YP_002803350.1 1176576 D 536232 CDS YP_002803351.1 226948260 7764398 1177523..1177846 1 NC_012563.1 identified by match to protein family HMM PF04993; TfoX domain-containing protein 1177846 7764398 CLM_1139 Clostridium botulinum A2 str. Kyoto TfoX domain-containing protein YP_002803351.1 1177523 D 536232 CDS YP_002803352.1 226948261 7765267 1177892..1178746 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1178746 7765267 CLM_1140 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803352.1 1177892 D 536232 CDS YP_002803353.1 226948262 7766616 1178984..1179235 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 1179235 7766616 CLM_1141 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803353.1 1178984 D 536232 CDS YP_002803354.1 226948263 7764885 1179878..1179991 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1179991 7764885 CLM_1142 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803354.1 1179878 D 536232 CDS YP_002803355.1 226948264 7767353 1180489..1181457 1 NC_012563.1 identified by match to protein family HMM PF00877; NlpC/P60 family protein 1181457 7767353 CLM_1144 Clostridium botulinum A2 str. Kyoto NlpC/P60 family protein YP_002803355.1 1180489 D 536232 CDS YP_002803356.1 226948265 7766277 complement(1182462..1183469) 1 NC_012563.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1183469 add 7766277 add Clostridium botulinum A2 str. Kyoto adenosine deaminase YP_002803356.1 1182462 R 536232 CDS YP_002803357.1 226948266 7765453 1184366..1186534 1 NC_012563.1 identified by match to protein family HMM TIGR03061; match to protein family HMM TIGR03062; putative phage infection protein 1186534 7765453 CLM_1146 Clostridium botulinum A2 str. Kyoto putative phage infection protein YP_002803357.1 1184366 D 536232 CDS YP_002803358.1 226948267 7764826 1186560..1188719 1 NC_012563.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR03061; match to protein family HMM TIGR03062; putative phage infection protein 1188719 7764826 CLM_1147 Clostridium botulinum A2 str. Kyoto putative phage infection protein YP_002803358.1 1186560 D 536232 CDS YP_002803359.1 226948268 7767006 complement(1189132..1189434) 1 NC_012563.1 hypothetical protein 1189434 7767006 CLM_1148 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803359.1 1189132 R 536232 CDS YP_002803360.1 226948269 7766118 1189640..1190395 1 NC_012563.1 hypothetical protein 1190395 7766118 CLM_1149 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803360.1 1189640 D 536232 CDS YP_002803361.1 226948270 7767186 1190639..1192768 1 NC_012563.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389; ATP-dependent DNA helicase RecQ 1192768 recQ 7767186 recQ Clostridium botulinum A2 str. Kyoto ATP-dependent DNA helicase RecQ YP_002803361.1 1190639 D 536232 CDS YP_002803362.1 226948271 7766307 1192879..1193310 1 NC_012563.1 identified by match to protein family HMM PF02915; rubrerythrin family protein 1193310 7766307 CLM_1151 Clostridium botulinum A2 str. Kyoto rubrerythrin family protein YP_002803362.1 1192879 D 536232 CDS YP_002803363.1 226948272 7766392 complement(1193594..1194139) 1 NC_012563.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; phosphodiesterase 1194139 7766392 CLM_1152 Clostridium botulinum A2 str. Kyoto phosphodiesterase YP_002803363.1 1193594 R 536232 CDS YP_002803364.1 226948273 7765529 1194775..1195158 1 NC_012563.1 identified by match to protein family HMM PF00072; response regulator 1195158 7765529 CLM_1153 Clostridium botulinum A2 str. Kyoto response regulator YP_002803364.1 1194775 D 536232 CDS YP_002803365.1 226948274 7764663 1195273..1197747 1 NC_012563.1 identified by match to protein family HMM PF07656; KWG repeat-containing protein 1197747 7764663 CLM_1154 Clostridium botulinum A2 str. Kyoto KWG repeat-containing protein YP_002803365.1 1195273 D 536232 CDS YP_002803366.1 226948275 7767750 1198195..1198410 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1198410 7767750 CLM_1155 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803366.1 1198195 D 536232 CDS YP_002803367.1 226948276 7765686 1198412..1199230 1 NC_012563.1 hypothetical protein 1199230 7765686 CLM_1156 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803367.1 1198412 D 536232 CDS YP_002803368.1 226948277 7764819 1199230..1199835 1 NC_012563.1 identified by match to protein family HMM PF04055; putative anaerobic ribonucleoside-triphosphate reductase activating protein 1199835 7764819 CLM_1157 Clostridium botulinum A2 str. Kyoto putative anaerobic ribonucleoside-triphosphate reductase activating protein YP_002803368.1 1199230 D 536232 CDS YP_002803369.1 226948278 7767924 1199837..1201510 1 NC_012563.1 identified by match to protein family HMM PF00004; ATPase, AAA family 1201510 7767924 CLM_1158 Clostridium botulinum A2 str. Kyoto ATPase, AAA family YP_002803369.1 1199837 D 536232 CDS YP_002803370.1 226948279 7767269 1201525..1202295 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1202295 7767269 CLM_1159 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803370.1 1201525 D 536232 CDS YP_002803371.1 226948280 7765266 1202776..1204299 1 NC_012563.1 identified by match to protein family HMM PF02652; match to protein family HMM PF03553; match to protein family HMM TIGR00795; L-lactate permease 1204299 lctP 7765266 lctP Clostridium botulinum A2 str. Kyoto L-lactate permease YP_002803371.1 1202776 D 536232 CDS YP_002803372.1 226948281 7764509 1204328..1205602 1 NC_012563.1 hypothetical protein 1205602 7764509 CLM_1161 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803372.1 1204328 D 536232 CDS YP_002803373.1 226948282 7767664 1205645..1206433 1 NC_012563.1 identified by match to protein family HMM PF01012; electron transfer flavoprotein subunit beta/FixA family protein 1206433 7767664 CLM_1162 Clostridium botulinum A2 str. Kyoto electron transfer flavoprotein subunit beta/FixA family protein YP_002803373.1 1205645 D 536232 CDS YP_002803374.1 226948283 7766779 1206465..1207667 1 NC_012563.1 identified by match to protein family HMM PF00766; match to protein family HMM PF01012; electron transfer flavoprotein subunit alpha/FixB family protein 1207667 7766779 CLM_1163 Clostridium botulinum A2 str. Kyoto electron transfer flavoprotein subunit alpha/FixB family protein YP_002803374.1 1206465 D 536232 CDS YP_002803375.1 226948284 7764388 1207728..1209125 1 NC_012563.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; putative glycolate oxidase 1209125 7764388 CLM_1164 Clostridium botulinum A2 str. Kyoto putative glycolate oxidase YP_002803375.1 1207728 D 536232 CDS YP_002803376.1 226948285 7765211 1209394..1209513 1 NC_012563.1 hypothetical protein 1209513 7765211 CLM_1165 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803376.1 1209394 D 536232 CDS YP_002803377.1 226948286 7767125 1209641..1210549 1 NC_012563.1 putative lipoprotein 1210549 7767125 CLM_1166 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002803377.1 1209641 D 536232 CDS YP_002803378.1 226948287 7767950 1210744..1211214 1 NC_012563.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1211214 7767950 CLM_1167 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002803378.1 1210744 D 536232 CDS YP_002803379.1 226948288 7766477 1211216..1211761 1 NC_012563.1 identified by match to protein family HMM PF04199; putative cyclase 1211761 7766477 CLM_1168 Clostridium botulinum A2 str. Kyoto putative cyclase YP_002803379.1 1211216 D 536232 CDS YP_002803380.1 226948289 7764821 complement(1211912..1213096) 1 NC_012563.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1213096 7764821 CLM_1169 Clostridium botulinum A2 str. Kyoto aspartate aminotransferase YP_002803380.1 1211912 R 536232 CDS YP_002803381.1 226948290 7764375 complement(1214025..1214603) 1 NC_012563.1 identified by match to protein family HMM PF04199; putative cyclase 1214603 7764375 CLM_1170 Clostridium botulinum A2 str. Kyoto putative cyclase YP_002803381.1 1214025 R 536232 CDS YP_002803382.1 226948291 7765179 1214762..1215286 1 NC_012563.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1215286 7765179 CLM_1171 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002803382.1 1214762 D 536232 CDS YP_002803383.1 226948292 7768054 1215589..1216410 1 NC_012563.1 identified by match to protein family HMM PF00376; match to protein family HMM PF06445; MerR family transcriptional regulator 1216410 7768054 CLM_1172 Clostridium botulinum A2 str. Kyoto MerR family transcriptional regulator YP_002803383.1 1215589 D 536232 CDS YP_002803384.1 226948293 7764965 1216625..1217323 1 NC_012563.1 identified by match to protein family HMM PF03483; B3/4 domain-containing protein 1217323 7764965 CLM_1173 Clostridium botulinum A2 str. Kyoto B3/4 domain-containing protein YP_002803384.1 1216625 D 536232 CDS YP_002803385.1 226948294 7765242 complement(1217599..1218888) 1 NC_012563.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1218888 aspC 7765242 aspC Clostridium botulinum A2 str. Kyoto aspartyl-tRNA synthetase YP_002803385.1 1217599 R 536232 CDS YP_002803386.1 226948295 7764405 1219434..1219991 1 NC_012563.1 hypothetical protein 1219991 7764405 CLM_1175 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803386.1 1219434 D 536232 CDS YP_002803387.1 226948296 7765992 1219995..1220558 1 NC_012563.1 identified by match to protein family HMM PF01066; CDP-alcohol phosphatidyltransferase family protein 1220558 7765992 CLM_1176 Clostridium botulinum A2 str. Kyoto CDP-alcohol phosphatidyltransferase family protein YP_002803387.1 1219995 D 536232 CDS YP_002803388.1 226948297 7764236 1220820..1221434 1 NC_012563.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1221434 7764236 CLM_1177 Clostridium botulinum A2 str. Kyoto TetR family transcriptional regulator YP_002803388.1 1220820 D 536232 CDS YP_002803389.1 226948298 7767781 1221450..1221938 1 NC_012563.1 hypothetical protein 1221938 7767781 CLM_1178 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803389.1 1221450 D 536232 CDS YP_002803390.1 226948299 7767010 complement(1222033..1222722) 1 NC_012563.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254; HAD superfamily hydrolase 1222722 7767010 CLM_1179 Clostridium botulinum A2 str. Kyoto HAD superfamily hydrolase YP_002803390.1 1222033 R 536232 CDS YP_002803391.1 226948300 7765819 1223037..1223726 1 NC_012563.1 identified by match to protein family HMM PF00027; cyclic nucleotide-binding domain-containing protein 1223726 7765819 CLM_1180 Clostridium botulinum A2 str. Kyoto cyclic nucleotide-binding domain-containing protein YP_002803391.1 1223037 D 536232 CDS YP_002803392.1 226948301 7764715 complement(1223853..1224437) 1 NC_012563.1 identified by match to protein family HMM PF01965; DJ-1/PfpI family protein 1224437 7764715 CLM_1181 Clostridium botulinum A2 str. Kyoto DJ-1/PfpI family protein YP_002803392.1 1223853 R 536232 CDS YP_002803393.1 226948302 7764575 1224593..1225486 1 NC_012563.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1225486 7764575 CLM_1182 Clostridium botulinum A2 str. Kyoto LysR family transcriptional regulator YP_002803393.1 1224593 D 536232 CDS YP_002803394.1 226948303 7767652 1225620..1226378 1 NC_012563.1 hypothetical protein 1226378 7767652 CLM_1183 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803394.1 1225620 D 536232 CDS YP_002803395.1 226948304 7768048 1226962..1227171 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF04023; putative ferrous iron transport protein A 1227171 7768048 CLM_1184 Clostridium botulinum A2 str. Kyoto putative ferrous iron transport protein A YP_002803395.1 1226962 D 536232 CDS YP_002803396.1 226948305 7764988 1227188..1227409 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by similarity to SP:P0AEL3; match to protein family HMM PF04023; ferrous iron transport protein A 1227409 feoA 7764988 feoA Clostridium botulinum A2 str. Kyoto ferrous iron transport protein A YP_002803396.1 1227188 D 536232 CDS YP_002803397.1 226948306 7764417 1227441..1229597 1 NC_012563.1 identified by similarity to SP:P33650; match to protein family HMM PF01926; match to protein family HMM PF02421; match to protein family HMM PF07664; match to protein family HMM PF07670; match to protein family HMM TIGR00231; match to protein family HMM TIGR00437; ferrous iron transport protein B 1229597 feoB 7764417 feoB Clostridium botulinum A2 str. Kyoto ferrous iron transport protein B YP_002803397.1 1227441 D 536232 CDS YP_002803398.1 226948307 7765245 1229618..1229764 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1229764 7765245 CLM_1187 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803398.1 1229618 D 536232 CDS YP_002803399.1 226948308 7764320 complement(1230159..1230596) 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1230596 7764320 CLM_1188 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803399.1 1230159 R 536232 CDS YP_002803400.1 226948309 7765354 1231063..1231863 1 NC_012563.1 identified by match to protein family HMM PF02557; D-alanyl-D-alanine carboxypeptidase family protein 1231863 7765354 CLM_1189 Clostridium botulinum A2 str. Kyoto D-alanyl-D-alanine carboxypeptidase family protein YP_002803400.1 1231063 D 536232 CDS YP_002803401.1 226948310 7766495 1232162..1232389 1 NC_012563.1 identified by match to protein family HMM TIGR03090; small acid-soluble spore protein Tlp 1232389 tlp 7766495 tlp Clostridium botulinum A2 str. Kyoto small acid-soluble spore protein Tlp YP_002803401.1 1232162 D 536232 CDS YP_002803402.1 226948311 7767609 1232607..1233293 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 1233293 7767609 CLM_1191 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002803402.1 1232607 D 536232 CDS YP_002803403.1 226948312 7764694 1233294..1234649 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 1234649 7764694 CLM_1192 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803403.1 1233294 D 536232 CDS YP_002803404.1 226948313 7766025 1234753..1234887 1 NC_012563.1 hypothetical protein 1234887 7766025 CLM_1193 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803404.1 1234753 D 536232 CDS YP_002803405.1 226948314 7766775 1235184..1236443 1 NC_012563.1 identified by match to protein family HMM PF00067; cytochrome P450 1236443 7766775 CLM_1194 Clostridium botulinum A2 str. Kyoto cytochrome P450 YP_002803405.1 1235184 D 536232 CDS YP_002803406.1 226948315 7767682 complement(1236583..1238391) 1 NC_012563.1 identified by match to protein family HMM PF00403; match to protein family HMM PF02683; heavy metal-associated domain-containing protein 1238391 7767682 CLM_1195 Clostridium botulinum A2 str. Kyoto heavy metal-associated domain-containing protein YP_002803406.1 1236583 R 536232 CDS YP_002803407.1 226948316 7766849 1238929..1239165 1 NC_012563.1 hypothetical protein 1239165 7766849 CLM_1196 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803407.1 1238929 D 536232 CDS YP_002803408.1 226948317 7768055 1239435..1240136 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 1240136 7768055 CLM_1197 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002803408.1 1239435 D 536232 CDS YP_002803409.1 226948318 7764927 1240136..1241542 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 1241542 7764927 CLM_1198 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803409.1 1240136 D 536232 CDS YP_002803410.1 226948319 7765297 complement(1241882..1242568) 1 NC_012563.1 hypothetical protein 1242568 7765297 CLM_1199 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803410.1 1241882 R 536232 CDS YP_002803411.1 226948320 7766184 complement(1242804..1243442) 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 1243442 7766184 CLM_1200 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002803411.1 1242804 R 536232 CDS YP_002803412.1 226948321 7767561 1243808..1244761 1 NC_012563.1 identified by match to protein family HMM PF01032; iron chelate uptake ABC transporter permease 1244761 7767561 CLM_1201 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter permease YP_002803412.1 1243808 D 536232 CDS YP_002803413.1 226948322 7764537 1244751..1245701 1 NC_012563.1 identified by match to protein family HMM PF01032; iron chelate uptake ABC transporter permease 1245701 7764537 CLM_1202 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter permease YP_002803413.1 1244751 D 536232 CDS YP_002803414.1 226948323 7766884 1245698..1246453 1 NC_012563.1 identified by match to protein family HMM PF00005; iron chelate uptake ABC transporter ATP-binding protein 1246453 7766884 CLM_1203 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter ATP-binding protein YP_002803414.1 1245698 D 536232 CDS YP_002803415.1 226948324 7766136 1246527..1247471 1 NC_012563.1 identified by match to protein family HMM PF01497; iron chelate uptake ABC transporter solute-binding protein 1247471 7766136 CLM_1204 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter solute-binding protein YP_002803415.1 1246527 D 536232 CDS YP_002803416.1 226948325 7766823 1247674..1248675 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 1248675 7766823 CLM_1205 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002803416.1 1247674 D 536232 CDS YP_002803417.1 226948326 7767690 1249191..1250993 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 1250993 7767690 CLM_1206 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein/permease YP_002803417.1 1249191 D 536232 CDS YP_002803418.1 226948327 7766814 1250995..1252710 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF02463; ABC transporter ATP-binding protein/permease 1252710 7766814 CLM_1207 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein/permease YP_002803418.1 1250995 D 536232 CDS YP_002803419.1 226948328 7767789 complement(1252917..1254290) 1 NC_012563.1 sensor histidine kinase 1254290 7767789 CLM_1208 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803419.1 1252917 R 536232 CDS YP_002803420.1 226948329 7765602 complement(1254293..1255000) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; DNA-binding response regulator 1255000 7765602 CLM_1209 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002803420.1 1254293 R 536232 CDS YP_002803421.1 226948330 7766377 complement(1255088..1255957) 1 NC_012563.1 hypothetical protein 1255957 7766377 CLM_1210 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803421.1 1255088 R 536232 CDS YP_002803422.1 226948331 7765902 1257054..1260215 1 NC_012563.1 identified by match to protein family HMM PF01345; match to protein family HMM TIGR01451; BNR/Asp-box repeat-protein 1260215 7765902 CLM_1213 Clostridium botulinum A2 str. Kyoto BNR/Asp-box repeat-protein YP_002803422.1 1257054 D 536232 CDS YP_002803423.1 226948332 7764581 1260403..1261902 1 NC_012563.1 identified by similarity to GB:BAB16890.1; match to protein family HMM PF00041; match to protein family HMM PF00704; chitinase A 1261902 chiA 7764581 chiA Clostridium botulinum A2 str. Kyoto chitinase A YP_002803423.1 1260403 D 536232 CDS YP_002803424.1 226948333 7765458 1262230..1264272 1 NC_012563.1 identified by match to protein family HMM PF03190; hypothetical protein 1264272 7765458 CLM_1215 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803424.1 1262230 D 536232 CDS YP_002803425.1 226948334 7764649 1264595..1265590 1 NC_012563.1 identified by match to protein family HMM PF06081; hypothetical protein 1265590 7764649 CLM_1216 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803425.1 1264595 D 536232 CDS YP_002803426.1 226948335 7767742 1265755..1266339 1 NC_012563.1 hypothetical protein 1266339 7767742 CLM_1217 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803426.1 1265755 D 536232 CDS YP_002803427.1 226948336 7766887 1267156..1267521 1 NC_012563.1 identified by match to protein family HMM PF03551; PadR family transcriptional regulator 1267521 7766887 CLM_1218 Clostridium botulinum A2 str. Kyoto PadR family transcriptional regulator YP_002803427.1 1267156 D 536232 CDS YP_002803428.1 226948337 7766078 1267524..1268381 1 NC_012563.1 hypothetical protein 1268381 7766078 CLM_1219 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803428.1 1267524 D 536232 CDS YP_002803429.1 226948338 7765124 complement(1268983..1269684) 1 NC_012563.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family protein 1269684 7765124 CLM_1220 Clostridium botulinum A2 str. Kyoto CAAX amino terminal protease family protein YP_002803429.1 1268983 R 536232 CDS YP_002803430.1 226948339 7764369 complement(1269800..1270606) 1 NC_012563.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 1270606 7764369 CLM_1221 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002803430.1 1269800 R 536232 CDS YP_002803431.1 226948340 7767444 1271423..1272349 1 NC_012563.1 identified by match to protein family HMM PF04389; peptidase M28 1272349 7767444 CLM_1222 Clostridium botulinum A2 str. Kyoto peptidase M28 YP_002803431.1 1271423 D 536232 CDS YP_002803432.1 226948341 7764215 1272465..1272818 1 NC_012563.1 identified by match to protein family HMM PF08239; bacteriocin 1272818 7764215 CLM_1223 Clostridium botulinum A2 str. Kyoto bacteriocin YP_002803432.1 1272465 D 536232 CDS YP_002803433.1 226948342 7766857 complement(1273207..1275126) 1 NC_012563.1 identified by match to protein family HMM PF00005; drug resistance ABC transporter ATP-binding protein 1275126 7766857 CLM_1224 Clostridium botulinum A2 str. Kyoto drug resistance ABC transporter ATP-binding protein YP_002803433.1 1273207 R 536232 CDS YP_002803434.1 226948343 7764350 1275764..1276978 1 NC_012563.1 hypothetical protein 1276978 7764350 CLM_1225 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803434.1 1275764 D 536232 CDS YP_002803435.1 226948344 7764926 1277364..1277699 1 NC_012563.1 identified by match to protein family HMM PF03960; ArsC family protein 1277699 7764926 CLM_1226 Clostridium botulinum A2 str. Kyoto ArsC family protein YP_002803435.1 1277364 D 536232 CDS YP_002803436.1 226948345 7765658 1277946..1278839 1 NC_012563.1 radical SAM domain-containing protein 1278839 7765658 CLM_1227 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002803436.1 1277946 D 536232 CDS YP_002803437.1 226948346 7764301 1279048..1280466 1 NC_012563.1 identified by match to protein family HMM PF01266; match to protein family HMM PF04324; FAD-dependent oxidoreductase 1280466 7764301 CLM_1228 Clostridium botulinum A2 str. Kyoto FAD-dependent oxidoreductase YP_002803437.1 1279048 D 536232 CDS YP_002803438.1 226948347 7767850 1280522..1281778 1 NC_012563.1 identified by match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase 1281778 7767850 CLM_1229 Clostridium botulinum A2 str. Kyoto pyridine nucleotide-disulfide oxidoreductase YP_002803438.1 1280522 D 536232 CDS YP_002803439.1 226948348 7766761 1281781..1282149 1 NC_012563.1 identified by match to protein family HMM PF07892; hypothetical protein 1282149 7766761 CLM_1230 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803439.1 1281781 D 536232 CDS YP_002803440.1 226948349 7766990 1282238..1283575 1 NC_012563.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00712; match to protein family HMM TIGR00881; glycerol-3-phosphate transporter 1283575 glpT 7766990 glpT Clostridium botulinum A2 str. Kyoto glycerol-3-phosphate transporter YP_002803440.1 1282238 D 536232 CDS YP_002803441.1 226948350 7765890 1284158..1285849 1 NC_012563.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1285849 argS 7765890 argS Clostridium botulinum A2 str. Kyoto arginyl-tRNA synthetase YP_002803441.1 1284158 D 536232 CDS YP_002803442.1 226948351 7767217 1286248..1287378 1 NC_012563.1 associated with arginine deiminase pathway genes; probably functions in arginine catabolism; transaminase 1287378 arcT 7767217 arcT Clostridium botulinum A2 str. Kyoto transaminase YP_002803442.1 1286248 D 536232 CDS YP_002803443.1 226948352 7766520 1287517..1287897 1 NC_012563.1 identified by match to protein family HMM PF00571; CBS domain-containing protein 1287897 7766520 CLM_1234 Clostridium botulinum A2 str. Kyoto CBS domain-containing protein YP_002803443.1 1287517 D 536232 CDS YP_002803444.1 226948353 7767465 complement(1288106..1288264) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1288264 7767465 CLM_1235 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803444.1 1288106 R 536232 CDS YP_002803445.1 226948354 7766457 complement(1288290..1290053) 1 NC_012563.1 identified by match to protein family HMM PF01926; match to protein family HMM PF02421; match to protein family HMM PF07664; match to protein family HMM PF07670; match to protein family HMM PF08477; match to protein family HMM TIGR00231; match to protein family HMM TIGR00437; ferrous iron transport protein B 1290053 feoB 7766457 feoB Clostridium botulinum A2 str. Kyoto ferrous iron transport protein B YP_002803445.1 1288290 R 536232 CDS YP_002803446.1 226948355 7766060 complement(1290068..1290289) 1 NC_012563.1 identified by match to protein family HMM PF04023; ferrous ion transport protein A 1290289 feoA 7766060 feoA Clostridium botulinum A2 str. Kyoto ferrous ion transport protein A YP_002803446.1 1290068 R 536232 CDS YP_002803447.1 226948356 7764433 1290615..1291010 1 NC_012563.1 identified by match to protein family HMM PF07238; hypothetical protein 1291010 7764433 CLM_1238 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803447.1 1290615 D 536232 CDS YP_002803448.1 226948357 7767840 1291222..1291947 1 NC_012563.1 identified by match to protein family HMM TIGR01488; match to protein family HMM TIGR01490; haloacid dehalogenase 1291947 7767840 CLM_1239 Clostridium botulinum A2 str. Kyoto haloacid dehalogenase YP_002803448.1 1291222 D 536232 CDS YP_002803449.1 226948358 7766973 1292856..1294439 1 NC_012563.1 identified by match to protein family HMM PF02839; putative glycosyl hydrolase 1294439 7766973 CLM_1240 Clostridium botulinum A2 str. Kyoto putative glycosyl hydrolase YP_002803449.1 1292856 D 536232 CDS YP_002803450.1 226948359 7766636 1294851..1295318 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1295318 7766636 CLM_1241 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803450.1 1294851 D 536232 CDS YP_002803451.1 226948360 7764766 1295596..1296552 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF09383; methionine ABC transporter ATP-binding protein 1296552 7764766 CLM_1243 Clostridium botulinum A2 str. Kyoto methionine ABC transporter ATP-binding protein YP_002803451.1 1295596 D 536232 CDS YP_002803452.1 226948361 7767056 1296554..1297195 1 NC_012563.1 identified by match to protein family HMM PF00528; methionine ABC transporter permease 1297195 7767056 CLM_1244 Clostridium botulinum A2 str. Kyoto methionine ABC transporter permease YP_002803452.1 1296554 D 536232 CDS YP_002803453.1 226948362 7768071 1297250..1298062 1 NC_012563.1 identified by match to protein family HMM PF03180; NLPA family lipoprotein 1298062 7768071 CLM_1245 Clostridium botulinum A2 str. Kyoto NLPA family lipoprotein YP_002803453.1 1297250 D 536232 CDS YP_002803454.1 226948363 7766268 1298250..1299062 1 NC_012563.1 identified by match to protein family HMM PF03180; NLPA family lipoprotein 1299062 7766268 CLM_1246 Clostridium botulinum A2 str. Kyoto NLPA family lipoprotein YP_002803454.1 1298250 D 536232 CDS YP_002803455.1 226948364 7765403 1299291..1300457 1 NC_012563.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; amidohydrolase family protein 1300457 7765403 CLM_1247 Clostridium botulinum A2 str. Kyoto amidohydrolase family protein YP_002803455.1 1299291 D 536232 CDS YP_002803456.1 226948365 7765199 1301029..1301658 1 NC_012563.1 hypothetical protein 1301658 7765199 CLM_1248 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803456.1 1301029 D 536232 CDS YP_002803457.1 226948366 7764567 1302164..1302856 1 NC_012563.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 1302856 7764567 CLM_1249 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002803457.1 1302164 D 536232 CDS YP_002803458.1 226948367 7767513 1303101..1303964 1 NC_012563.1 identified by match to protein family HMM PF02588; hypothetical protein 1303964 7767513 CLM_1250 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803458.1 1303101 D 536232 CDS YP_002803459.1 226948368 7765870 1304173..1304385 1 NC_012563.1 hypothetical protein 1304385 7765870 CLM_1251 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803459.1 1304173 D 536232 CDS YP_002803460.1 226948369 7765873 complement(1304610..1306067) 1 NC_012563.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1306067 gltX 7765873 gltX Clostridium botulinum A2 str. Kyoto glutamyl-tRNA synthetase YP_002803460.1 1304610 R 536232 CDS YP_002803461.1 226948370 7764771 1306492..1307508 1 NC_012563.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase 1307508 gap 7764771 gap Clostridium botulinum A2 str. Kyoto glyceraldehyde-3-phosphate dehydrogenase YP_002803461.1 1306492 D 536232 CDS YP_002803462.1 226948371 7767988 complement(1307753..1309261) 1 NC_012563.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; metallo-beta-lactamase family protein 1309261 7767988 CLM_1254 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002803462.1 1307753 R 536232 CDS YP_002803463.1 226948372 7765086 1309627..1309776 1 NC_012563.1 hypothetical protein 1309776 7765086 CLM_1255 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803463.1 1309627 D 536232 CDS YP_002803464.1 226948373 7766330 1309919..1310563 1 NC_012563.1 identified by match to protein family HMM PF01966; HD domain-containing protein 1310563 7766330 CLM_1256 Clostridium botulinum A2 str. Kyoto HD domain-containing protein YP_002803464.1 1309919 D 536232 CDS YP_002803465.1 226948374 7765642 1310619..1311989 1 NC_012563.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase family protein 1311989 7765642 CLM_1257 Clostridium botulinum A2 str. Kyoto aldehyde dehydrogenase family protein YP_002803465.1 1310619 D 536232 CDS YP_002803466.1 226948375 7767701 complement(1312072..1313469) 1 NC_012563.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 1313469 7767701 CLM_1258 Clostridium botulinum A2 str. Kyoto sodium:alanine symporter family protein YP_002803466.1 1312072 R 536232 CDS YP_002803467.1 226948376 7766850 complement(1314066..1315442) 1 NC_012563.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 1315442 7766850 CLM_1259 Clostridium botulinum A2 str. Kyoto sodium:alanine symporter family protein YP_002803467.1 1314066 R 536232 CDS YP_002803468.1 226948377 7766844 1315880..1316317 1 NC_012563.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1316317 7766844 CLM_1260 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002803468.1 1315880 D 536232 CDS YP_002803469.1 226948378 7765903 1316335..1317702 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM TIGR00797; MATE efflux family protein 1317702 7765903 CLM_1261 Clostridium botulinum A2 str. Kyoto MATE efflux family protein YP_002803469.1 1316335 D 536232 CDS YP_002803470.1 226948379 7765059 1318121..1318666 1 NC_012563.1 TPR domain-containing protein 1318666 7765059 CLM_1262 Clostridium botulinum A2 str. Kyoto TPR domain-containing protein YP_002803470.1 1318121 D 536232 CDS YP_002803471.1 226948380 7767429 1318765..1319742 1 NC_012563.1 hypothetical protein 1319742 7767429 CLM_1263 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803471.1 1318765 D 536232 CDS YP_002803472.1 226948381 7764774 1320545..1321783 1 NC_012563.1 putative ABC transporter solute-binding protein 1321783 7764774 CLM_1264 Clostridium botulinum A2 str. Kyoto putative ABC transporter solute-binding protein YP_002803472.1 1320545 D 536232 CDS YP_002803473.1 226948382 7767639 1321785..1322657 1 NC_012563.1 identified by match to protein family HMM PF00528; ABC transporter permease 1322657 7767639 CLM_1266 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002803473.1 1321785 D 536232 CDS YP_002803474.1 226948383 7768029 1322676..1323482 1 NC_012563.1 identified by match to protein family HMM PF00528; ABC transporter permease 1323482 7768029 CLM_1267 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002803474.1 1322676 D 536232 CDS YP_002803475.1 226948384 7764689 1323494..1324513 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1324513 7764689 CLM_1268 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803475.1 1323494 D 536232 CDS YP_002803476.1 226948385 7765292 1324816..1325775 1 NC_012563.1 hypothetical protein 1325775 7765292 CLM_1269 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803476.1 1324816 D 536232 CDS YP_002803477.1 226948386 7766954 1325879..1326430 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1326430 7766954 CLM_1270 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803477.1 1325879 D 536232 CDS YP_002803478.1 226948387 7767617 1326440..1326775 1 NC_012563.1 hypothetical protein 1326775 7767617 CLM_1271 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803478.1 1326440 D 536232 CDS YP_002803479.1 226948388 7764278 1326851..1327129 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1327129 7764278 CLM_1272 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803479.1 1326851 D 536232 CDS YP_002803480.1 226948389 7764750 1327130..1327726 1 NC_012563.1 identified by match to protein family HMM PF03956; hypothetical protein 1327726 7764750 CLM_1273 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803480.1 1327130 D 536232 CDS YP_002803481.1 226948390 7765827 1328014..1328568 1 NC_012563.1 identified by similarity to SP:P77791; match to protein family HMM PF00132; maltose O-acetyltransferase 1328568 maa 7765827 maa Clostridium botulinum A2 str. Kyoto maltose O-acetyltransferase YP_002803481.1 1328014 D 536232 CDS YP_002803482.1 226948391 7767127 complement(1328858..1329841) 1 NC_012563.1 identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM PF08279; match to protein family HMM TIGR00121; birA bifunctional protein 1329841 birA 7767127 birA Clostridium botulinum A2 str. Kyoto birA bifunctional protein YP_002803482.1 1328858 R 536232 CDS YP_002803483.1 226948392 7765437 1330005..1330208 1 NC_012563.1 putative heavy metal-binding protein 1330208 7765437 CLM_1276 Clostridium botulinum A2 str. Kyoto putative heavy metal-binding protein YP_002803483.1 1330005 D 536232 CDS YP_002803484.1 226948393 7765146 1330484..1330921 1 NC_012563.1 identified by match to protein family HMM PF00571; CBS domain-containing protein 1330921 7765146 CLM_1277 Clostridium botulinum A2 str. Kyoto CBS domain-containing protein YP_002803484.1 1330484 D 536232 CDS YP_002803485.1 226948394 7768088 1331081..1332514 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 1332514 7768088 CLM_1278 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803485.1 1331081 D 536232 CDS YP_002803486.1 226948395 7766815 complement(1332626..1332751) 1 NC_012563.1 hypothetical protein 1332751 7766815 CLM_1279 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803486.1 1332626 R 536232 CDS YP_002803487.1 226948396 7765945 1333381..1334160 1 NC_012563.1 hypothetical protein 1334160 7765945 CLM_1280 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803487.1 1333381 D 536232 CDS YP_002803488.1 226948397 7766638 1334661..1335995 1 NC_012563.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01769; match to protein family HMM PF03448; match to protein family HMM TIGR00400; magnesium transporter 1335995 mgtE 7766638 mgtE Clostridium botulinum A2 str. Kyoto magnesium transporter YP_002803488.1 1334661 D 536232 CDS YP_002803489.1 226948398 7767878 1337004..1338077 1 NC_012563.1 identified by match to protein family HMM PF00266; class V aminotransferase 1338077 7767878 CLM_1282 Clostridium botulinum A2 str. Kyoto class V aminotransferase YP_002803489.1 1337004 D 536232 CDS YP_002803490.1 226948399 7764467 1338303..1339247 1 NC_012563.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase family protein 1339247 7764467 CLM_1283 Clostridium botulinum A2 str. Kyoto D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_002803490.1 1338303 D 536232 CDS YP_002803491.1 226948400 7765567 1339225..1340553 1 NC_012563.1 identified by match to protein family HMM PF06245; hypothetical protein 1340553 7765567 CLM_1284 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803491.1 1339225 D 536232 CDS YP_002803492.1 226948401 7765768 1341206..1342396 1 NC_012563.1 identified by match to protein family HMM PF00258; match to protein family HMM PF00753; metallo-beta-lactamase/flavodoxin domain-containing protein 1342396 7765768 CLM_1285 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase/flavodoxin domain-containing protein YP_002803492.1 1341206 D 536232 CDS YP_002803493.1 226948402 7764723 1342563..1346852 1 NC_012563.1 identified by match to protein family HMM PF01869; match to protein family HMM TIGR00241; putative CoA-substrate-specific enzyme activase 1346852 7764723 CLM_1286 Clostridium botulinum A2 str. Kyoto putative CoA-substrate-specific enzyme activase YP_002803493.1 1342563 D 536232 CDS YP_002803494.1 226948403 7765847 complement(1346926..1348440) 1 NC_012563.1 identified by match to protein family HMM PF02028; match to protein family HMM TIGR00842; choline/carnitine/betaine transporter 1348440 7765847 CLM_1287 Clostridium botulinum A2 str. Kyoto choline/carnitine/betaine transporter YP_002803494.1 1346926 R 536232 CDS YP_002803495.1 226948404 7766975 1348782..1349408 1 NC_012563.1 identified by match to protein family HMM PF00392; match to protein family HMM PF02080; GntR family transcriptional regulator 1349408 7766975 CLM_1288 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002803495.1 1348782 D 536232 CDS YP_002803496.1 226948405 7767968 1349519..1350019 1 NC_012563.1 hypothetical protein 1350019 7767968 CLM_1289 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803496.1 1349519 D 536232 CDS YP_002803497.1 226948406 7764448 1350318..1350878 1 NC_012563.1 identified by similarity to SP:P21369; match to protein family HMM PF00857; pncA family protein 1350878 7764448 CLM_1290 Clostridium botulinum A2 str. Kyoto pncA family protein YP_002803497.1 1350318 D 536232 CDS YP_002803498.1 226948407 7765640 1351037..1351348 1 NC_012563.1 identified by match to protein family HMM PF00581; rhodanese domain-containing protein 1351348 7765640 CLM_1291 Clostridium botulinum A2 str. Kyoto rhodanese domain-containing protein YP_002803498.1 1351037 D 536232 CDS YP_002803499.1 226948408 7766227 1351424..1351888 1 NC_012563.1 hypothetical protein 1351888 7766227 CLM_1292 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803499.1 1351424 D 536232 CDS YP_002803500.1 226948409 7766705 1352165..1352365 1 NC_012563.1 hypothetical protein 1352365 7766705 CLM_1293 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803500.1 1352165 D 536232 CDS YP_002803501.1 226948410 7764536 1352543..1353454 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein 1353454 7764536 CLM_1294 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803501.1 1352543 D 536232 CDS YP_002803502.1 226948411 7765155 1353615..1354187 1 NC_012563.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1354187 xpt 7765155 xpt Clostridium botulinum A2 str. Kyoto xanthine phosphoribosyltransferase YP_002803502.1 1353615 D 536232 CDS YP_002803503.1 226948412 7766138 1354485..1355066 1 NC_012563.1 hypothetical protein 1355066 7766138 CLM_1296 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803503.1 1354485 D 536232 CDS YP_002803504.1 226948413 7765024 1355362..1356744 1 NC_012563.1 identified by match to protein family HMM PF00581; putative thiosulfate sulfurtransferase 1356744 7765024 CLM_1297 Clostridium botulinum A2 str. Kyoto putative thiosulfate sulfurtransferase YP_002803504.1 1355362 D 536232 CDS YP_002803505.1 226948414 7767865 1356943..1357365 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1357365 7767865 CLM_1298 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803505.1 1356943 D 536232 CDS YP_002803506.1 226948415 7767613 1357709..1358812 1 NC_012563.1 identified by match to protein family HMM PF01594; putative transporter 1358812 7767613 CLM_1299 Clostridium botulinum A2 str. Kyoto putative transporter YP_002803506.1 1357709 D 536232 CDS YP_002803507.1 226948416 7768066 1358992..1359321 1 NC_012563.1 identified by match to protein family HMM PF03819; MazG family protein 1359321 7768066 CLM_1300 Clostridium botulinum A2 str. Kyoto MazG family protein YP_002803507.1 1358992 D 536232 CDS YP_002803508.1 226948417 7765406 1359458..1361197 1 NC_012563.1 hypothetical protein 1361197 7765406 CLM_1301 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803508.1 1359458 D 536232 CDS YP_002803509.1 226948418 7764574 complement(1361336..1361503) 1 NC_012563.1 hypothetical protein 1361503 7764574 CLM_1302 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803509.1 1361336 R 536232 CDS YP_002803510.1 226948419 7767691 1361775..1361915 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1361915 7767691 CLM_1303 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803510.1 1361775 D 536232 CDS YP_002803511.1 226948420 7766782 1362097..1363296 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1363296 7766782 CLM_1304 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803511.1 1362097 D 536232 CDS YP_002803512.1 226948421 7764624 1363689..1364735 1 NC_012563.1 identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 1364735 7764624 CLM_1305 Clostridium botulinum A2 str. Kyoto ABC transporter substrate-binding protein YP_002803512.1 1363689 D 536232 CDS YP_002803513.1 226948422 7766311 1364737..1366425 1 NC_012563.1 identified by match to protein family HMM PF00528; ABC transporter permease 1366425 7766311 CLM_1306 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002803513.1 1364737 D 536232 CDS YP_002803514.1 226948423 7765494 1366388..1367323 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1367323 7765494 CLM_1307 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803514.1 1366388 D 536232 CDS YP_002803515.1 226948424 7764582 complement(1367388..1368182) 1 NC_012563.1 hypothetical protein 1368182 7764582 CLM_1308 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803515.1 1367388 R 536232 CDS YP_002803516.1 226948425 7765558 1368483..1369634 1 NC_012563.1 hypothetical protein 1369634 7765558 CLM_1309 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803516.1 1368483 D 536232 CDS YP_002803517.1 226948426 7764495 1370026..1371189 1 NC_012563.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1371189 rpsA 7764495 rpsA Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S1 YP_002803517.1 1370026 D 536232 CDS YP_002803518.1 226948427 7768008 1371372..1371791 1 NC_012563.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051; thioesterase family protein 1371791 7768008 CLM_1311 Clostridium botulinum A2 str. Kyoto thioesterase family protein YP_002803518.1 1371372 D 536232 CDS YP_002803519.1 226948428 7766706 1371963..1372379 1 NC_012563.1 hypothetical protein 1372379 7766706 CLM_1312 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803519.1 1371963 D 536232 CDS YP_002803520.1 226948429 7764330 1373250..1374257 1 NC_012563.1 identified by match to protein family HMM PF04392; putative ABC transporter substrate-binding protein 1374257 7764330 CLM_1313 Clostridium botulinum A2 str. Kyoto putative ABC transporter substrate-binding protein YP_002803520.1 1373250 D 536232 CDS YP_002803521.1 226948430 7765164 1374257..1375162 1 NC_012563.1 identified by match to protein family HMM PF02653; ABC transporter permease 1375162 7765164 CLM_1314 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002803521.1 1374257 D 536232 CDS YP_002803522.1 226948431 7766560 1375125..1375919 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1375919 7766560 CLM_1315 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803522.1 1375125 D 536232 CDS YP_002803523.1 226948432 7767631 1376248..1376550 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1376550 7767631 CLM_1316 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803523.1 1376248 D 536232 CDS YP_002803524.1 226948433 7768114 1376983..1378626 1 NC_012563.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1378626 7768114 CLM_1317 Clostridium botulinum A2 str. Kyoto aspartate aminotransferase YP_002803524.1 1376983 D 536232 CDS YP_002803525.1 226948434 7764987 complement(1378753..1379634) 1 NC_012563.1 identified by match to protein family HMM PF00892; match to protein family HMM PF03151; match to protein family HMM PF08449; UAA transporter family 1379634 7764987 CLM_1318 Clostridium botulinum A2 str. Kyoto UAA transporter family YP_002803525.1 1378753 R 536232 CDS YP_002803526.1 226948435 7764590 1380220..1381317 1 NC_012563.1 identified by match to protein family HMM PF00294; match to protein family HMM PF08279; PfkB family kinase 1381317 7764590 CLM_1319 Clostridium botulinum A2 str. Kyoto PfkB family kinase YP_002803526.1 1380220 D 536232 CDS YP_002803527.1 226948436 7765843 1381311..1382234 1 NC_012563.1 identified by match to protein family HMM PF04227; indigoidine synthase A family protein 1382234 7765843 CLM_1320 Clostridium botulinum A2 str. Kyoto indigoidine synthase A family protein YP_002803527.1 1381311 D 536232 CDS YP_002803528.1 226948437 7766395 1382726..1383637 1 NC_012563.1 identified by match to protein family HMM PF02558; match to protein family HMM PF08546; match to protein family HMM TIGR00745; 2-dehydropantoate 2-reductase 1383637 panE 7766395 panE Clostridium botulinum A2 str. Kyoto 2-dehydropantoate 2-reductase YP_002803528.1 1382726 D 536232 CDS YP_002803529.1 226948438 7767175 1383944..1384576 1 NC_012563.1 identified by similarity to SP:Q49135; match to protein family HMM PF04961; methenyltetrahydrofolate cyclohydrolase 1384576 7767175 CLM_1322 Clostridium botulinum A2 str. Kyoto methenyltetrahydrofolate cyclohydrolase YP_002803529.1 1383944 D 536232 CDS YP_002803530.1 226948439 7765005 1384576..1385424 1 NC_012563.1 identified by similarity to SP:P54382; match to protein family HMM PF00763; match to protein family HMM PF02882; methylenetetrahydrofolate dehydrogenase 1385424 folD 7765005 folD Clostridium botulinum A2 str. Kyoto methylenetetrahydrofolate dehydrogenase YP_002803530.1 1384576 D 536232 CDS YP_002803531.1 226948440 7766402 1385718..1386512 1 NC_012563.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD hydrolase 1386512 7766402 CLM_1324 Clostridium botulinum A2 str. Kyoto HAD hydrolase YP_002803531.1 1385718 D 536232 CDS YP_002803532.1 226948441 7766784 complement(1386739..1387245) 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1387245 7766784 CLM_1325 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002803532.1 1386739 R 536232 CDS YP_002803533.1 226948442 7764794 1387426..1387569 1 NC_012563.1 hypothetical protein 1387569 7764794 CLM_1326 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803533.1 1387426 D 536232 CDS YP_002803534.1 226948443 7765879 1387686..1388417 1 NC_012563.1 hypothetical protein 1388417 7765879 CLM_1327 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803534.1 1387686 D 536232 CDS YP_002803535.1 226948444 7767081 1388537..1389346 1 NC_012563.1 identified by match to protein family HMM PF02535; ZIP family zinc transporter 1389346 7767081 CLM_1328 Clostridium botulinum A2 str. Kyoto ZIP family zinc transporter YP_002803535.1 1388537 D 536232 CDS YP_002803536.1 226948445 7767008 1390018..1390455 1 NC_012563.1 identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738; rrf2 family protein 1390455 7767008 CLM_1329 Clostridium botulinum A2 str. Kyoto rrf2 family protein YP_002803536.1 1390018 D 536232 CDS YP_002803537.1 226948446 7768036 1390784..1391713 1 NC_012563.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; cysteine synthase A 1391713 cysK 7768036 cysK Clostridium botulinum A2 str. Kyoto cysteine synthase A YP_002803537.1 1390784 D 536232 CDS YP_002803538.1 226948447 7764225 1391758..1392426 1 NC_012563.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 1392426 7764225 CLM_1331 Clostridium botulinum A2 str. Kyoto amino acid ABC transporter permease YP_002803538.1 1391758 D 536232 CDS YP_002803539.1 226948448 7765536 1392461..1393285 1 NC_012563.1 identified by match to protein family HMM PF00497; polar amino acid uptake ABC transporter amino acid-binding protein 1393285 7765536 CLM_1332 Clostridium botulinum A2 str. Kyoto polar amino acid uptake ABC transporter amino acid-binding protein YP_002803539.1 1392461 D 536232 CDS YP_002803540.1 226948449 7764849 1393386..1394516 1 NC_012563.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; class V aminotransferase 1394516 7764849 CLM_1333 Clostridium botulinum A2 str. Kyoto class V aminotransferase YP_002803540.1 1393386 D 536232 CDS YP_002803541.1 226948450 7765741 1394588..1395388 1 NC_012563.1 identified by match to protein family HMM PF01171; match to protein family HMM PF06508; match to protein family HMM TIGR00268; hypothetical protein 1395388 7765741 CLM_1334 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803541.1 1394588 D 536232 CDS YP_002803542.1 226948451 7767151 1395543..1395671 1 NC_012563.1 hypothetical protein 1395671 7767151 CLM_1335 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803542.1 1395543 D 536232 CDS YP_002803543.1 226948452 7766970 1395787..1396857 1 NC_012563.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1396857 mnmA 7766970 mnmA Clostridium botulinum A2 str. Kyoto tRNA-specific 2-thiouridylase MnmA YP_002803543.1 1395787 D 536232 CDS YP_002803544.1 226948453 7765817 complement(1396935..1397147) 1 NC_012563.1 hypothetical protein 1397147 7765817 CLM_1337 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803544.1 1396935 R 536232 CDS YP_002803545.1 226948454 7764860 1397419..1398138 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; LytTr family DNA-binding response regulator 1398138 7764860 CLM_1338 Clostridium botulinum A2 str. Kyoto LytTr family DNA-binding response regulator YP_002803545.1 1397419 D 536232 CDS YP_002803546.1 226948455 7766701 1398135..1399478 1 NC_012563.1 identified by match to protein family HMM PF02518; sensor histidine kinase 1399478 7766701 CLM_1340 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803546.1 1398135 D 536232 CDS YP_002803547.1 226948456 7764526 1399852..1400775 1 NC_012563.1 identified by match to protein family HMM PF00005; bacitracin ABC transporter ATP-binding protein BcrA 1400775 bcrA 7764526 bcrA Clostridium botulinum A2 str. Kyoto bacitracin ABC transporter ATP-binding protein BcrA YP_002803547.1 1399852 D 536232 CDS YP_002803548.1 226948457 7767365 1400768..1401511 1 NC_012563.1 hypothetical protein 1401511 7767365 CLM_1342 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803548.1 1400768 D 536232 CDS YP_002803549.1 226948458 7765220 1401934..1403820 1 NC_012563.1 identified by match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase family protein 1403820 7765220 CLM_1343 Clostridium botulinum A2 str. Kyoto glycerophosphoryl diester phosphodiesterase family protein YP_002803549.1 1401934 D 536232 CDS YP_002803550.1 226948459 7764326 1404175..1404339 1 NC_012563.1 hypothetical protein 1404339 7764326 CLM_1344 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803550.1 1404175 D 536232 CDS YP_002803551.1 226948460 7764969 complement(1404379..1407897) 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176; pyruvate ferredoxin oxidoreductase 1407897 7764969 CLM_1345 Clostridium botulinum A2 str. Kyoto pyruvate ferredoxin oxidoreductase YP_002803551.1 1404379 R 536232 CDS YP_002803552.1 226948461 7768056 1407995..1408135 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1408135 7768056 CLM_1346 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803552.1 1407995 D 536232 CDS YP_002803553.1 226948462 7766421 1408272..1408733 1 NC_012563.1 identified by match to protein family HMM PF08922; hypothetical protein 1408733 7766421 CLM_1347 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803553.1 1408272 D 536232 CDS YP_002803554.1 226948463 7765815 1409033..1410508 1 NC_012563.1 identified by match to protein family HMM PF02696; hypothetical protein 1410508 7765815 CLM_1348 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803554.1 1409033 D 536232 CDS YP_002803555.1 226948464 7767234 1411097..1412824 1 NC_012563.1 identified by match to protein family HMM PF01593; amine oxidase, flavin-containing 1412824 7767234 CLM_1349 Clostridium botulinum A2 str. Kyoto amine oxidase, flavin-containing YP_002803555.1 1411097 D 536232 CDS YP_002803556.1 226948465 7766461 complement(1413069..1413959) 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 1413959 7766461 CLM_1351 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002803556.1 1413069 R 536232 CDS YP_002803557.1 226948466 7766965 1414159..1415535 1 NC_012563.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00792; sugar transporter 1415535 7766965 CLM_1352 Clostridium botulinum A2 str. Kyoto sugar transporter YP_002803557.1 1414159 D 536232 CDS YP_002803558.1 226948467 7764262 1415549..1416877 1 NC_012563.1 identified by match to protein family HMM PF02055; O-glycosyl hydrolase, family 30 1416877 7764262 CLM_1353 Clostridium botulinum A2 str. Kyoto O-glycosyl hydrolase, family 30 YP_002803558.1 1415549 D 536232 CDS YP_002803559.1 226948468 7768117 1416941..1417882 1 NC_012563.1 identified by match to protein family HMM PF00480; ROK family protein 1417882 7768117 CLM_1354 Clostridium botulinum A2 str. Kyoto ROK family protein YP_002803559.1 1416941 D 536232 CDS YP_002803560.1 226948469 7767002 1417885..1419330 1 NC_012563.1 identified by match to protein family HMM PF00232; putative beta-glucosidase 1419330 7767002 CLM_1355 Clostridium botulinum A2 str. Kyoto putative beta-glucosidase YP_002803560.1 1417885 D 536232 CDS YP_002803561.1 226948470 7765897 1419998..1421626 1 NC_012563.1 identified by similarity to SP:P19584; match to protein family HMM PF00686; match to protein family HMM PF01373; beta-amylase 1421626 7765897 CLM_1356 Clostridium botulinum A2 str. Kyoto beta-amylase YP_002803561.1 1419998 D 536232 CDS YP_002803562.1 226948471 7766956 1422265..1423467 1 NC_012563.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1423467 tyrS 7766956 tyrS Clostridium botulinum A2 str. Kyoto tyrosyl-tRNA synthetase YP_002803562.1 1422265 D 536232 CDS YP_002803563.1 226948472 7766617 1423748..1424119 1 NC_012563.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1424119 7766617 CLM_1359 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002803563.1 1423748 D 536232 CDS YP_002803564.1 226948473 7764722 1424112..1424984 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1424984 7764722 CLM_1360 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803564.1 1424112 D 536232 CDS YP_002803565.1 226948474 7764387 1424985..1425731 1 NC_012563.1 hypothetical protein 1425731 7764387 CLM_1361 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803565.1 1424985 D 536232 CDS YP_002803566.1 226948475 7767478 complement(1425867..1426238) 1 NC_012563.1 hypothetical protein 1426238 7767478 CLM_1362 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803566.1 1425867 R 536232 CDS YP_002803567.1 226948476 7766932 1426294..1426485 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1426485 7766932 CLM_1363 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803567.1 1426294 D 536232 CDS YP_002803568.1 226948477 7766093 1426576..1427469 1 NC_012563.1 hypothetical protein 1427469 7766093 CLM_1364 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803568.1 1426576 D 536232 CDS YP_002803569.1 226948478 7764703 1427658..1430009 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1430009 7764703 CLM_1365 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803569.1 1427658 D 536232 CDS YP_002803570.1 226948479 7767891 1430087..1431601 1 NC_012563.1 identified by match to protein family HMM PF00704; match to protein family HMM PF01476; match to protein family HMM PF08239; glycosyl hydrolase, family 18 1431601 7767891 CLM_1367 Clostridium botulinum A2 str. Kyoto glycosyl hydrolase, family 18 YP_002803570.1 1430087 D 536232 CDS YP_002803571.1 226948480 7767481 1431775..1433034 1 NC_012563.1 identified by match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; putative sensory box-containing diguanylate cyclase 1433034 7767481 CLM_1368 Clostridium botulinum A2 str. Kyoto putative sensory box-containing diguanylate cyclase YP_002803571.1 1431775 D 536232 CDS YP_002803572.1 226948481 7764882 1433434..1434108 1 NC_012563.1 identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719; L-serine dehydratase, iron-sulfur-dependent subunit beta 1434108 sdhB 7764882 sdhB Clostridium botulinum A2 str. Kyoto L-serine dehydratase, iron-sulfur-dependent subunit beta YP_002803572.1 1433434 D 536232 CDS YP_002803573.1 226948482 7766086 1434121..1435011 1 NC_012563.1 identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718; L-serine dehydratase, iron-sulfur-dependent subunit alpha 1435011 sdhA 7766086 sdhA Clostridium botulinum A2 str. Kyoto L-serine dehydratase, iron-sulfur-dependent subunit alpha YP_002803573.1 1434121 D 536232 CDS YP_002803574.1 226948483 7765809 1435435..1435644 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1435644 7765809 CLM_1372 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803574.1 1435435 D 536232 CDS YP_002803575.1 226948484 7766399 complement(1435803..1435946) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1435946 7766399 CLM_1373 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803575.1 1435803 R 536232 CDS YP_002803576.1 226948485 7767265 1436030..1436149 1 NC_012563.1 hypothetical protein 1436149 7767265 CLM_1374 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803576.1 1436030 D 536232 CDS YP_002803577.1 226948486 7764628 1436219..1436803 1 NC_012563.1 hypothetical protein 1436803 7764628 CLM_1375 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803577.1 1436219 D 536232 CDS YP_002803578.1 226948487 7765855 complement(1436825..1437793) 1 NC_012563.1 identified by match to protein family HMM PF01244; dipeptidase family protein 1437793 7765855 CLM_1376 Clostridium botulinum A2 str. Kyoto dipeptidase family protein YP_002803578.1 1436825 R 536232 CDS YP_002803579.1 226948488 7765573 complement(1438178..1438870) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1438870 7765573 CLM_1377 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803579.1 1438178 R 536232 CDS YP_002803580.1 226948489 7766152 complement(1438976..1440259) 1 NC_012563.1 identified by match to protein family HMM PF02687; putative ABC transporter permease 1440259 7766152 CLM_1378 Clostridium botulinum A2 str. Kyoto putative ABC transporter permease YP_002803580.1 1438976 R 536232 CDS YP_002803581.1 226948490 7764720 complement(1440261..1441076) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1441076 7764720 CLM_1379 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803581.1 1440261 R 536232 CDS YP_002803582.1 226948491 7766494 complement(1441113..1441787) 1 NC_012563.1 identified by match to protein family HMM PF00005; putative oligopeptide ABC transporter ATP-binding protein 1441787 7766494 CLM_1380 Clostridium botulinum A2 str. Kyoto putative oligopeptide ABC transporter ATP-binding protein YP_002803582.1 1441113 R 536232 CDS YP_002803583.1 226948492 7767573 complement(1441960..1442808) 1 NC_012563.1 identified by match to protein family HMM PF00528; putative oligopeptide ABC transporter permease 1442808 7767573 CLM_1381 Clostridium botulinum A2 str. Kyoto putative oligopeptide ABC transporter permease YP_002803583.1 1441960 R 536232 CDS YP_002803584.1 226948493 7764322 complement(1442814..1443767) 1 NC_012563.1 identified by match to protein family HMM PF00528; putative oligopeptide ABC transporter permease 1443767 7764322 CLM_1382 Clostridium botulinum A2 str. Kyoto putative oligopeptide ABC transporter permease YP_002803584.1 1442814 R 536232 CDS YP_002803585.1 226948494 7765306 complement(1443966..1445564) 1 NC_012563.1 identified by match to protein family HMM PF00496; putative oligopeptide ABC transporter oligopeptide-binding protein 1445564 7765306 CLM_1383 Clostridium botulinum A2 str. Kyoto putative oligopeptide ABC transporter oligopeptide-binding protein YP_002803585.1 1443966 R 536232 CDS YP_002803586.1 226948495 7766959 1445855..1446016 1 NC_012563.1 hypothetical protein 1446016 7766959 CLM_1384 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803586.1 1445855 D 536232 CDS YP_002803587.1 226948496 7767705 1446050..1446322 1 NC_012563.1 identified by similarity to SP:Q45537; CotJB protein 1446322 cotJB 7767705 cotJB Clostridium botulinum A2 str. Kyoto CotJB protein YP_002803587.1 1446050 D 536232 CDS YP_002803588.1 226948497 7765082 1446353..1446925 1 NC_012563.1 identified by similarity to SP:Q45538; match to protein family HMM PF05067; CotJC protein 1446925 cotJC 7765082 cotJC Clostridium botulinum A2 str. Kyoto CotJC protein YP_002803588.1 1446353 D 536232 CDS YP_002803589.1 226948498 7766431 1447155..1448174 1 NC_012563.1 hypothetical protein 1448174 7766431 CLM_1387 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803589.1 1447155 D 536232 CDS YP_002803590.1 226948499 7766792 1448191..1449255 1 NC_012563.1 hypothetical protein 1449255 7766792 CLM_1388 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803590.1 1448191 D 536232 CDS YP_002803591.1 226948500 7765929 1449849..1450340 1 NC_012563.1 identified by match to protein family HMM PF04525; hypothetical protein 1450340 7765929 CLM_1389 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803591.1 1449849 D 536232 CDS YP_002803592.1 226948501 7766837 complement(1450581..1450973) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1450973 7766837 CLM_1390 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803592.1 1450581 R 536232 CDS YP_002803593.1 226948502 7764248 1451320..1451946 1 NC_012563.1 identified by match to protein family HMM PF00692; deoxyuridine 5'-triphosphate nucleotidohydrolase 1451946 dut 7764248 dut Clostridium botulinum A2 str. Kyoto deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002803593.1 1451320 D 536232 CDS YP_002803594.1 226948503 7765073 complement(1452007..1452198) 1 NC_012563.1 identified by match to protein family HMM TIGR02861; small acid-soluble spore protein, H-type 1452198 7765073 CLM_1392 Clostridium botulinum A2 str. Kyoto small acid-soluble spore protein, H-type YP_002803594.1 1452007 R 536232 CDS YP_002803595.1 226948504 7766657 complement(1452714..1453469) 1 NC_012563.1 hypothetical protein 1453469 7766657 CLM_1393 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803595.1 1452714 R 536232 CDS YP_002803596.1 226948505 7767535 1453863..1454009 1 NC_012563.1 hypothetical protein 1454009 7767535 CLM_1394 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803596.1 1453863 D 536232 CDS YP_002803597.1 226948506 7764881 complement(1454127..1454660) 1 NC_012563.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883; DNA-binding protein 1454660 7764881 CLM_1395 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002803597.1 1454127 R 536232 CDS YP_002803598.1 226948507 7765956 1455083..1456132 1 NC_012563.1 hypothetical protein 1456132 7765956 CLM_1396 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803598.1 1455083 D 536232 CDS YP_002803599.1 226948508 7765475 1456564..1457151 1 NC_012563.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1457151 7765475 CLM_1398 Clostridium botulinum A2 str. Kyoto TetR family transcriptional regulator YP_002803599.1 1456564 D 536232 CDS YP_002803600.1 226948509 7767699 1457166..1457393 1 NC_012563.1 hypothetical protein 1457393 7767699 CLM_1399 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803600.1 1457166 D 536232 CDS YP_002803601.1 226948510 7766355 1457390..1458121 1 NC_012563.1 identified by match to protein family HMM PF00005; bacitracin transport ATP-binding protein BcrA 1458121 7766355 CLM_1400 Clostridium botulinum A2 str. Kyoto bacitracin transport ATP-binding protein BcrA YP_002803601.1 1457390 D 536232 CDS YP_002803602.1 226948511 7767498 1458118..1458810 1 NC_012563.1 hypothetical protein 1458810 7767498 CLM_1401 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803602.1 1458118 D 536232 CDS YP_002803603.1 226948512 7767259 1458830..1459051 1 NC_012563.1 hypothetical protein 1459051 7767259 CLM_1402 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803603.1 1458830 D 536232 CDS YP_002803604.1 226948513 7764420 1459063..1459296 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1459296 7764420 CLM_1403 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803604.1 1459063 D 536232 CDS YP_002803605.1 226948514 7766002 complement(1459792..1461228) 1 NC_012563.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 1461228 7766002 CLM_1404 Clostridium botulinum A2 str. Kyoto sodium:alanine symporter family protein YP_002803605.1 1459792 R 536232 CDS YP_002803606.1 226948515 7766875 1462397..1462705 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1462705 7766875 CLM_1405 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803606.1 1462397 D 536232 CDS YP_002803607.1 226948516 7766727 1463368..1463571 1 NC_012563.1 identified by match to protein family HMM PF01381; putative DNA-binding protein 1463571 7766727 CLM_1406 Clostridium botulinum A2 str. Kyoto putative DNA-binding protein YP_002803607.1 1463368 D 536232 CDS YP_002803608.1 226948517 7764636 1463694..1463825 1 NC_012563.1 hypothetical protein 1463825 7764636 CLM_1407 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803608.1 1463694 D 536232 CDS YP_002803609.1 226948518 7765461 1464472..1464729 1 NC_012563.1 hypothetical protein 1464729 7765461 CLM_1408 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803609.1 1464472 D 536232 CDS YP_002803610.1 226948519 7766321 1465012..1465758 1 NC_012563.1 putative lipoprotein 1465758 7766321 CLM_1409 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002803610.1 1465012 D 536232 CDS YP_002803611.1 226948520 7767174 1466077..1466304 1 NC_012563.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02196; glutaredoxin-like protein, YruB-family 1466304 7767174 CLM_1410 Clostridium botulinum A2 str. Kyoto glutaredoxin-like protein, YruB-family YP_002803611.1 1466077 D 536232 CDS YP_002803612.1 226948521 7767997 complement(1466336..1467796) 1 NC_012563.1 identified by match to protein family HMM PF00171; putative glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent 1467796 7767997 CLM_1411 Clostridium botulinum A2 str. Kyoto putative glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent YP_002803612.1 1466336 R 536232 CDS YP_002803613.1 226948522 7764258 complement(1467836..1468777) 1 NC_012563.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; putative thioredoxin reductase 1468777 7764258 CLM_1412 Clostridium botulinum A2 str. Kyoto putative thioredoxin reductase YP_002803613.1 1467836 R 536232 CDS YP_002803614.1 226948523 7767619 1469562..1469939 1 NC_012563.1 GrdX protein 1469939 grdX 7767619 grdX Clostridium botulinum A2 str. Kyoto GrdX protein YP_002803614.1 1469562 D 536232 CDS YP_002803615.1 226948524 7766506 1470030..1471316 1 NC_012563.1 identified by match to protein family HMM PF09338; glycine reductase subunits ABC 1471316 grdE 7766506 grdE Clostridium botulinum A2 str. Kyoto glycine reductase subunits ABC YP_002803615.1 1470030 D 536232 CDS YP_002803616.1 226948525 7765826 1471349..1472650 1 NC_012563.1 Selenoprotein. identified by match to protein family HMM PF07355; match to protein family HMM TIGR01917; match to protein family HMM TIGR01918; glycine reductase, selenoprotein B 1472650 grdB 7765826 grdB Clostridium botulinum A2 str. Kyoto glycine reductase, selenoprotein B YP_002803616.1 1471349 D 536232 CDS YP_002803617.1 226948526 7765100 1472801..1473742 1 NC_012563.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF07992; match to protein family HMM TIGR01292; thioredoxin-disulfide reductase 1473742 trxB 7765100 trxB Clostridium botulinum A2 str. Kyoto thioredoxin-disulfide reductase YP_002803617.1 1472801 D 536232 CDS YP_002803618.1 226948527 7765299 1473776..1474096 1 NC_012563.1 identified by match to protein family HMM PF00085; thioredoxin family protein 1474096 7765299 CLM_1419 Clostridium botulinum A2 str. Kyoto thioredoxin family protein YP_002803618.1 1473776 D 536232 CDS YP_002803619.1 226948528 7764292 1474182..1474313 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; glycine reductase complex component A 1474313 grdA 7764292 grdA Clostridium botulinum A2 str. Kyoto glycine reductase complex component A YP_002803619.1 1474182 D 536232 CDS YP_002803620.1 226948529 7765432 1474329..1474658 1 NC_012563.1 GrdA accepts a carboxymethylselenoether from protein B and transfers it to protein C forming a protein C-bound acetyl-thioester; oxidized GrdA is then reduced by thioredoxin; putative glycine/sarcosine/betaine reductase complex protein A 1474658 grdA 7765432 grdA Clostridium botulinum A2 str. Kyoto putative glycine/sarcosine/betaine reductase complex protein A YP_002803620.1 1474329 D 536232 CDS YP_002803621.1 226948530 7764609 1474753..1476291 1 NC_012563.1 identified by match to protein family HMM PF08545; glycine reductase complex component C subunit beta 1476291 grdC 7764609 grdC Clostridium botulinum A2 str. Kyoto glycine reductase complex component C subunit beta YP_002803621.1 1474753 D 536232 CDS YP_002803622.1 226948531 7767438 1476307..1477473 1 NC_012563.1 identified by match to protein family HMM PF02504; glycine reductase complex component C subunit alpha 1477473 grdD 7767438 grdD Clostridium botulinum A2 str. Kyoto glycine reductase complex component C subunit alpha YP_002803622.1 1476307 D 536232 CDS YP_002803623.1 226948532 7766427 1477900..1478511 1 NC_012563.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 1478511 7766427 CLM_1424 Clostridium botulinum A2 str. Kyoto 3-methyladenine DNA glycosylase YP_002803623.1 1477900 D 536232 CDS YP_002803624.1 226948533 7765302 1478577..1480802 1 NC_012563.1 identified by match to protein family HMM PF07669; restriction endonuclease family protein 1480802 7765302 CLM_1425 Clostridium botulinum A2 str. Kyoto restriction endonuclease family protein YP_002803624.1 1478577 D 536232 CDS YP_002803625.1 226948534 7765166 1481239..1482450 1 NC_012563.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway; methylthioribose kinase 1482450 mtnK 7765166 mtnK Clostridium botulinum A2 str. Kyoto methylthioribose kinase YP_002803625.1 1481239 D 536232 CDS YP_002803626.1 226948535 7767322 1482590..1483639 1 NC_012563.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway; methylthioribose-1-phosphate isomerase 1483639 mtnA 7767322 mtnA Clostridium botulinum A2 str. Kyoto methylthioribose-1-phosphate isomerase YP_002803626.1 1482590 D 536232 CDS YP_002803627.1 226948536 7766847 1483663..1483773 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1483773 7766847 CLM_1428 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803627.1 1483663 D 536232 CDS YP_002803628.1 226948537 7765423 1483790..1484437 1 NC_012563.1 identified by match to protein family HMM PF00596; aldolase, class II, AraD/FucA subfamily 1484437 7765423 CLM_1429 Clostridium botulinum A2 str. Kyoto aldolase, class II, AraD/FucA subfamily YP_002803628.1 1483790 D 536232 CDS YP_002803629.1 226948538 7765692 1484611..1485405 1 NC_012563.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator 1485405 7765692 CLM_1430 Clostridium botulinum A2 str. Kyoto DeoR family transcriptional regulator YP_002803629.1 1484611 D 536232 CDS YP_002803630.1 226948539 7765549 1485714..1486073 1 NC_012563.1 hypothetical protein 1486073 7765549 CLM_1431 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803630.1 1485714 D 536232 CDS YP_002803631.1 226948540 7765824 complement(1486439..1487314) 1 NC_012563.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 1487314 7765824 CLM_1432 Clostridium botulinum A2 str. Kyoto cation efflux family protein YP_002803631.1 1486439 R 536232 CDS YP_002803632.1 226948541 7764705 1487562..1488290 1 NC_012563.1 identified by match to protein family HMM PF04239; hypothetical protein 1488290 7764705 CLM_1433 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803632.1 1487562 D 536232 CDS YP_002803633.1 226948542 7767245 1488452..1488817 1 NC_012563.1 hypothetical protein 1488817 7767245 CLM_1434 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803633.1 1488452 D 536232 CDS YP_002803634.1 226948543 7766471 1488945..1489283 1 NC_012563.1 hypothetical protein 1489283 7766471 CLM_1435 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803634.1 1488945 D 536232 CDS YP_002803635.1 226948544 7766008 1489280..1489753 1 NC_012563.1 hypothetical protein 1489753 7766008 CLM_1436 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803635.1 1489280 D 536232 CDS YP_002803636.1 226948545 7765130 1490288..1490680 1 NC_012563.1 hypothetical protein 1490680 7765130 CLM_1437 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803636.1 1490288 D 536232 CDS YP_002803637.1 226948546 7764548 1490728..1491435 1 NC_012563.1 hypothetical protein 1491435 7764548 CLM_1438 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803637.1 1490728 D 536232 CDS YP_002803638.1 226948547 7767399 complement(1491506..1491682) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1491682 7767399 CLM_1439 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803638.1 1491506 R 536232 CDS YP_002803639.1 226948548 7766876 complement(1492063..1492542) 1 NC_012563.1 identified by match to protein family HMM PF09579; sporulation protein YtfJ 1492542 7766876 CLM_1440 Clostridium botulinum A2 str. Kyoto sporulation protein YtfJ YP_002803639.1 1492063 R 536232 CDS YP_002803640.1 226948549 7765464 complement(1492567..1493112) 1 NC_012563.1 membrane associated protein 1493112 7765464 CLM_1441 Clostridium botulinum A2 str. Kyoto membrane associated protein YP_002803640.1 1492567 R 536232 CDS YP_002803641.1 226948550 7766521 1494007..1494252 1 NC_012563.1 hypothetical protein 1494252 7766521 CLM_1442 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803641.1 1494007 D 536232 CDS YP_002803642.1 226948551 7766902 1494280..1494576 1 NC_012563.1 hypothetical protein 1494576 7766902 CLM_1443 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803642.1 1494280 D 536232 CDS YP_002803643.1 226948552 7766690 1494633..1496930 1 NC_012563.1 putative molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 1496930 7766690 CLM_1444 Clostridium botulinum A2 str. Kyoto xanthine dehydrogenase subunit XdhA YP_002803643.1 1494633 D 536232 CDS YP_002803644.1 226948553 7767837 1496944..1497828 1 NC_012563.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 1497828 7767837 CLM_1445 Clostridium botulinum A2 str. Kyoto xanthine dehydrogenase subunit XdhB YP_002803644.1 1496944 D 536232 CDS YP_002803645.1 226948554 7764972 1497860..1498333 1 NC_012563.1 identified by match to protein family HMM PF00111; match to protein family HMM PF01799; xanthine dehydrogenase family protein iron-sulfur binding subunit 1498333 7764972 CLM_1446 Clostridium botulinum A2 str. Kyoto xanthine dehydrogenase family protein iron-sulfur binding subunit YP_002803645.1 1497860 D 536232 CDS YP_002803646.1 226948555 7765905 1498449..1498922 1 NC_012563.1 identified by match to protein family HMM PF00383; guanine deaminase 1498922 7765905 CLM_1447 Clostridium botulinum A2 str. Kyoto guanine deaminase YP_002803646.1 1498449 D 536232 CDS YP_002803647.1 226948556 7766096 1499310..1501505 1 NC_012563.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 1501505 topB 7766096 topB Clostridium botulinum A2 str. Kyoto DNA topoisomerase III YP_002803647.1 1499310 D 536232 CDS YP_002803648.1 226948557 7766237 1501978..1502583 1 NC_012563.1 identified by match to protein family HMM PF02659; hypothetical protein 1502583 7766237 CLM_1449 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803648.1 1501978 D 536232 CDS YP_002803649.1 226948558 7767496 1502650..1502886 1 NC_012563.1 hypothetical protein 1502886 7767496 CLM_1450 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803649.1 1502650 D 536232 CDS YP_002803650.1 226948559 7764382 complement(1502963..1503094) 1 NC_012563.1 hypothetical protein 1503094 7764382 CLM_1451 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803650.1 1502963 R 536232 CDS YP_002803651.1 226948560 7766751 1503613..1504266 1 NC_012563.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; putative translaldolase 1504266 7766751 CLM_1452 Clostridium botulinum A2 str. Kyoto putative translaldolase YP_002803651.1 1503613 D 536232 CDS YP_002803652.1 226948561 7766123 1504667..1506331 1 NC_012563.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649; RNA-metabolising metallo-beta-lactamase 1506331 7766123 CLM_1453 Clostridium botulinum A2 str. Kyoto RNA-metabolising metallo-beta-lactamase YP_002803652.1 1504667 D 536232 CDS YP_002803653.1 226948562 7764873 1506636..1507988 1 NC_012563.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 1507988 7764873 CLM_1454 Clostridium botulinum A2 str. Kyoto sodium:alanine symporter family protein YP_002803653.1 1506636 D 536232 CDS YP_002803654.1 226948563 7767500 1508309..1509154 1 NC_012563.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; GGDEF domain-containing protein 1509154 7767500 CLM_1455 Clostridium botulinum A2 str. Kyoto GGDEF domain-containing protein YP_002803654.1 1508309 D 536232 CDS YP_002803655.1 226948564 7765511 1509147..1510799 1 NC_012563.1 STE like transcription factor domain-containing protein 1510799 7765511 CLM_1456 Clostridium botulinum A2 str. Kyoto STE like transcription factor domain-containing protein YP_002803655.1 1509147 D 536232 CDS YP_002803656.1 226948565 7767880 1510805..1512067 1 NC_012563.1 identified by match to protein family HMM PF00535; group 2 family glycosyl transferase 1512067 7767880 CLM_1457 Clostridium botulinum A2 str. Kyoto group 2 family glycosyl transferase YP_002803656.1 1510805 D 536232 CDS YP_002803657.1 226948566 7767925 1512360..1514456 1 NC_012563.1 cellulose synthase domain-containing protein 1514456 7767925 CLM_1458 Clostridium botulinum A2 str. Kyoto cellulose synthase domain-containing protein YP_002803657.1 1512360 D 536232 CDS YP_002803658.1 226948567 7767077 1514872..1515966 1 NC_012563.1 hypothetical protein 1515966 7767077 CLM_1459 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803658.1 1514872 D 536232 CDS YP_002803659.1 226948568 7765046 1516194..1516358 1 NC_012563.1 hypothetical protein 1516358 7765046 CLM_1460 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803659.1 1516194 D 536232 CDS YP_002803660.1 226948569 7767687 1516693..1517496 1 NC_012563.1 hypothetical protein 1517496 7767687 CLM_1461 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803660.1 1516693 D 536232 CDS YP_002803661.1 226948570 7765919 1517772..1518038 1 NC_012563.1 identified by match to protein family HMM PF02583; hypothetical protein 1518038 7765919 CLM_1462 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803661.1 1517772 D 536232 CDS YP_002803662.1 226948571 7765159 1518075..1520510 1 NC_012563.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR00003; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper-exporting ATPase 1520510 7765159 CLM_1463 Clostridium botulinum A2 str. Kyoto copper-exporting ATPase YP_002803662.1 1518075 D 536232 CDS YP_002803663.1 226948572 7766655 1520633..1520848 1 NC_012563.1 identified by match to protein family HMM PF00403; copper chaperone CopZ 1520848 copZ 7766655 copZ Clostridium botulinum A2 str. Kyoto copper chaperone CopZ YP_002803663.1 1520633 D 536232 CDS YP_002803664.1 226948573 7765256 1521150..1523522 1 NC_012563.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; P-type cation-transporting ATPase 1523522 7765256 CLM_1465 Clostridium botulinum A2 str. Kyoto P-type cation-transporting ATPase YP_002803664.1 1521150 D 536232 CDS YP_002803665.1 226948574 7767667 1523818..1525536 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 1525536 7767667 CLM_1466 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein/permease YP_002803665.1 1523818 D 536232 CDS YP_002803666.1 226948575 7766791 1525876..1526670 1 NC_012563.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family protein 1526670 7766791 CLM_1467 Clostridium botulinum A2 str. Kyoto CAAX amino terminal protease family protein YP_002803666.1 1525876 D 536232 CDS YP_002803667.1 226948576 7767102 1526834..1527190 1 NC_012563.1 identified by match to protein family HMM PF02579; dinitrogenase iron-molybdenum cofactor family protein 1527190 7767102 CLM_1468 Clostridium botulinum A2 str. Kyoto dinitrogenase iron-molybdenum cofactor family protein YP_002803667.1 1526834 D 536232 CDS YP_002803668.1 226948577 7766137 1527461..1528153 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 1528153 7766137 CLM_1469 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002803668.1 1527461 D 536232 CDS YP_002803669.1 226948578 7765034 1528150..1529397 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 1529397 7765034 CLM_1470 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803669.1 1528150 D 536232 CDS YP_002803670.1 226948579 7764458 1531865..1532758 1 NC_012563.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; DegV family protein 1532758 7764458 CLM_1473 Clostridium botulinum A2 str. Kyoto DegV family protein YP_002803670.1 1531865 D 536232 CDS YP_002803671.1 226948580 7767769 complement(1532795..1533259) 1 NC_012563.1 identified by match to protein family HMM PF01243; 5-nitroimidazole antibiotic resistance protein 1533259 7767769 CLM_1474 Clostridium botulinum A2 str. Kyoto 5-nitroimidazole antibiotic resistance protein YP_002803671.1 1532795 R 536232 CDS YP_002803672.1 226948581 7766904 1533378..1533497 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1533497 7766904 CLM_1475 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803672.1 1533378 D 536232 CDS YP_002803673.1 226948582 7767712 1533510..1533893 1 NC_012563.1 hypothetical protein 1533893 7767712 CLM_1476 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803673.1 1533510 D 536232 CDS YP_002803674.1 226948583 7766840 1533886..1534008 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1534008 7766840 CLM_1477 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803674.1 1533886 D 536232 CDS YP_002803675.1 226948584 7765937 1534093..1534248 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative; hypothetical protein 1534248 7765937 CLM_1478 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803675.1 1534093 D 536232 CDS YP_002803676.1 226948585 7765092 1534524..1534718 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1534718 7765092 CLM_1479 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803676.1 1534524 D 536232 CDS YP_002803677.1 226948586 7767538 1534993..1535223 1 NC_012563.1 hypothetical protein 1535223 7767538 CLM_1480 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803677.1 1534993 D 536232 CDS YP_002803678.1 226948587 7767858 1535331..1535897 1 NC_012563.1 hypothetical protein 1535897 7767858 CLM_1481 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803678.1 1535331 D 536232 CDS YP_002803679.1 226948588 7766591 1535961..1536425 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 1536425 7766591 CLM_1482 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803679.1 1535961 D 536232 CDS YP_002803680.1 226948589 7767316 1536465..1537136 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase 1537136 7767316 CLM_1483 Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase YP_002803680.1 1536465 D 536232 CDS YP_002803681.1 226948590 7766385 1538280..1538462 1 NC_012563.1 hypothetical protein 1538462 7766385 CLM_1484 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803681.1 1538280 D 536232 CDS YP_002803682.1 226948591 7767310 1538476..1538721 1 NC_012563.1 phage protein 1538721 7767310 CLM_1485 Clostridium botulinum A2 str. Kyoto phage protein YP_002803682.1 1538476 D 536232 CDS YP_002803683.1 226948592 7765163 1538879..1539175 1 NC_012563.1 putative lipoprotein 1539175 7765163 CLM_1486 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002803683.1 1538879 D 536232 CDS YP_002803684.1 226948593 7765744 1539209..1539484 1 NC_012563.1 hypothetical protein 1539484 7765744 CLM_1487 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803684.1 1539209 D 536232 CDS YP_002803685.1 226948594 7766891 1539938..1540153 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 1540153 7766891 CLM_1488 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803685.1 1539938 D 536232 CDS YP_002803686.1 226948595 7766502 1540191..1540619 1 NC_012563.1 identified by match to protein family HMM PF01230; HIT family protein 1540619 7766502 CLM_1489 Clostridium botulinum A2 str. Kyoto HIT family protein YP_002803686.1 1540191 D 536232 CDS YP_002803687.1 226948596 7767606 complement(1540775..1541149) 1 NC_012563.1 hypothetical protein 1541149 7767606 CLM_1490 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803687.1 1540775 R 536232 CDS YP_002803688.1 226948597 7764677 1541441..1542199 1 NC_012563.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750; type IV leader peptidase family protein 1542199 7764677 CLM_1491 Clostridium botulinum A2 str. Kyoto type IV leader peptidase family protein YP_002803688.1 1541441 D 536232 CDS YP_002803689.1 226948598 7765762 1542792..1543919 1 NC_012563.1 identified by match to protein family HMM PF07907; hypothetical protein 1543919 7765762 CLM_1492 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803689.1 1542792 D 536232 CDS YP_002803690.1 226948599 7764818 1544701..1546068 1 NC_012563.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 1546068 trkA 7764818 trkA Clostridium botulinum A2 str. Kyoto potassium transporter peripheral membrane component YP_002803690.1 1544701 D 536232 CDS YP_002803691.1 226948600 7767820 1546065..1547510 1 NC_012563.1 identified by match to protein family HMM PF02386; Trk system potassium uptake protein TrkH 1547510 trkH 7767820 trkH Clostridium botulinum A2 str. Kyoto Trk system potassium uptake protein TrkH YP_002803691.1 1546065 D 536232 CDS YP_002803692.1 226948601 7767100 1547917..1550484 1 NC_012563.1 identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573; helicase, UvrD/REP/exonuclease family protein 1550484 7767100 CLM_1495 Clostridium botulinum A2 str. Kyoto helicase, UvrD/REP/exonuclease family protein YP_002803692.1 1547917 D 536232 CDS YP_002803693.1 226948602 7767972 complement(1551059..1552189) 1 NC_012563.1 identified by match to protein family HMM PF07853; hypothetical protein 1552189 7767972 CLM_1496 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803693.1 1551059 R 536232 CDS YP_002803694.1 226948603 7767128 complement(1552204..1552578) 1 NC_012563.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1552578 7767128 CLM_1497 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002803694.1 1552204 R 536232 CDS YP_002803695.1 226948604 7765186 complement(1553035..1553814) 1 NC_012563.1 identified by match to protein family HMM PF01476; match to protein family HMM PF07486; putative cell wall hydrolase 1553814 7765186 CLM_1498 Clostridium botulinum A2 str. Kyoto putative cell wall hydrolase YP_002803695.1 1553035 R 536232 CDS YP_002803696.1 226948605 7764381 1554590..1555177 1 NC_012563.1 identified by match to protein family HMM PF00301; match to protein family HMM PF02915; rubrerythrin 1555177 rbr 7764381 rbr Clostridium botulinum A2 str. Kyoto rubrerythrin YP_002803696.1 1554590 D 536232 CDS YP_002803697.1 226948606 7767499 1555652..1557112 1 NC_012563.1 identified by match to protein family HMM PF04122; N-acetylmuramoyl-L-alanine amidase 1557112 7767499 CLM_1501 Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase YP_002803697.1 1555652 D 536232 CDS YP_002803698.1 226948607 7767715 complement(1557414..1559444) 1 NC_012563.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR02002; PTS system glucose-specific transporter subunit IIABC 1559444 ptsG 7767715 ptsG Clostridium botulinum A2 str. Kyoto PTS system glucose-specific transporter subunit IIABC YP_002803698.1 1557414 R 536232 CDS YP_002803699.1 226948608 7765504 1559900..1560547 1 NC_012563.1 identified by match to protein family HMM PF01255; UDP pyrophosphate synthetase 1560547 7765504 CLM_1503 Clostridium botulinum A2 str. Kyoto UDP pyrophosphate synthetase YP_002803699.1 1559900 D 536232 CDS YP_002803700.1 226948609 7766388 1560933..1561382 1 NC_012563.1 hypothetical protein 1561382 7766388 CLM_1504 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803700.1 1560933 D 536232 CDS YP_002803701.1 226948610 7765396 1561677..1562090 1 NC_012563.1 identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738; putative transcriptional regulator 1562090 7765396 CLM_1505 Clostridium botulinum A2 str. Kyoto putative transcriptional regulator YP_002803701.1 1561677 D 536232 CDS YP_002803702.1 226948611 7766639 1562299..1564185 1 NC_012563.1 identified by match to protein family HMM PF03063; match to protein family HMM TIGR01702; carbon monoxide dehydrogenase 1564185 7766639 CLM_1506 Clostridium botulinum A2 str. Kyoto carbon monoxide dehydrogenase YP_002803702.1 1562299 D 536232 CDS YP_002803703.1 226948612 7768105 1564332..1564775 1 NC_012563.1 identified by match to protein family HMM PF00037; nitrate reductase, iron-sulfur subunit 1564775 7768105 CLM_1507 Clostridium botulinum A2 str. Kyoto nitrate reductase, iron-sulfur subunit YP_002803703.1 1564332 D 536232 CDS YP_002803704.1 226948613 7764404 1564974..1566200 1 NC_012563.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; nitrate reductase, NADH oxidase subunit 1566200 noxA 7764404 noxA Clostridium botulinum A2 str. Kyoto nitrate reductase, NADH oxidase subunit YP_002803704.1 1564974 D 536232 CDS YP_002803705.1 226948614 7765673 complement(1566242..1567216) 1 NC_012563.1 identified by match to protein family HMM PF00892; match to protein family HMM PF03151; putative transporter 1567216 7765673 CLM_1509 Clostridium botulinum A2 str. Kyoto putative transporter YP_002803705.1 1566242 R 536232 CDS YP_002803706.1 226948615 7767063 1567618..1568298 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; lipid A export ATP-binding/permease MsbA 1568298 7767063 CLM_1510 Clostridium botulinum A2 str. Kyoto lipid A export ATP-binding/permease MsbA YP_002803706.1 1567618 D 536232 CDS YP_002803707.1 226948616 7766600 1568599..1568913 1 NC_012563.1 hypothetical protein 1568913 7766600 CLM_1511 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803707.1 1568599 D 536232 CDS YP_002803708.1 226948617 7767511 complement(1569085..1569771) 1 NC_012563.1 identified by match to protein family HMM PF00027; match to protein family HMM PF00325; Crp/Fnr family transcriptional regulator 1569771 7767511 CLM_1512 Clostridium botulinum A2 str. Kyoto Crp/Fnr family transcriptional regulator YP_002803708.1 1569085 R 536232 CDS YP_002803709.1 226948618 7765176 1569888..1571087 1 NC_012563.1 identified by match to protein family HMM PF07690; major facilitator superfamily protein 1571087 7765176 CLM_1513 Clostridium botulinum A2 str. Kyoto major facilitator superfamily protein YP_002803709.1 1569888 D 536232 CDS YP_002803710.1 226948619 7767990 1571390..1572304 1 NC_012563.1 identified by match to protein family HMM PF01497; iron chelate uptake ABC transporter solute-binding protein 1572304 7767990 CLM_1514 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter solute-binding protein YP_002803710.1 1571390 D 536232 CDS YP_002803711.1 226948620 7767078 1572326..1573324 1 NC_012563.1 identified by match to protein family HMM PF01032; iron chelate uptake ABC transporter permease 1573324 7767078 CLM_1515 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter permease YP_002803711.1 1572326 D 536232 CDS YP_002803712.1 226948621 7765204 1573327..1574088 1 NC_012563.1 identified by match to protein family HMM PF00005; iron chelate uptake ABC transporter ATP-binding protein 1574088 7765204 CLM_1516 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter ATP-binding protein YP_002803712.1 1573327 D 536232 CDS YP_002803713.1 226948622 7764313 complement(1574309..1574644) 1 NC_012563.1 hypothetical protein 1574644 7764313 CLM_1517 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803713.1 1574309 R 536232 CDS YP_002803714.1 226948623 7767441 complement(1574719..1575996) 1 NC_012563.1 identified by match to protein family HMM PF00037; iron-sulfur cluster-binding protein 1575996 7767441 CLM_1518 Clostridium botulinum A2 str. Kyoto iron-sulfur cluster-binding protein YP_002803714.1 1574719 R 536232 CDS YP_002803715.1 226948624 7766536 1576416..1577261 1 NC_012563.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator 1577261 7766536 CLM_1519 Clostridium botulinum A2 str. Kyoto RpiR family transcriptional regulator YP_002803715.1 1576416 D 536232 CDS YP_002803716.1 226948625 7764700 1577541..1578449 1 NC_012563.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 1578449 murQ 7764700 murQ Clostridium botulinum A2 str. Kyoto N-acetylmuramic acid-6-phosphate etherase YP_002803716.1 1577541 D 536232 CDS YP_002803717.1 226948626 7768022 1578562..1579917 1 NC_012563.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; PTS system transporter subunit IIBC 1579917 7768022 CLM_1521 Clostridium botulinum A2 str. Kyoto PTS system transporter subunit IIBC YP_002803717.1 1578562 D 536232 CDS YP_002803718.1 226948627 7767013 1580108..1581184 1 NC_012563.1 identified by match to protein family HMM PF05913; hypothetical protein 1581184 7767013 CLM_1522 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803718.1 1580108 D 536232 CDS YP_002803719.1 226948628 7766292 1581516..1582124 1 NC_012563.1 identified by match to protein family HMM PF06475; hypothetical protein 1582124 7766292 CLM_1523 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803719.1 1581516 D 536232 CDS YP_002803720.1 226948629 7765279 1582407..1583048 1 NC_012563.1 identified by match to protein family HMM PF06555; hypothetical protein 1583048 7765279 CLM_1524 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803720.1 1582407 D 536232 CDS YP_002803721.1 226948630 7765062 1583354..1585225 1 NC_012563.1 hypothetical protein 1585225 7765062 CLM_1525 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803721.1 1583354 D 536232 CDS YP_002803722.1 226948631 7765040 1585278..1586516 1 NC_012563.1 putative cell-surface protein 1586516 7765040 CLM_1526 Clostridium botulinum A2 str. Kyoto putative cell-surface protein YP_002803722.1 1585278 D 536232 CDS YP_002803723.1 226948632 7766211 1586516..1587058 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1587058 7766211 CLM_1527 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803723.1 1586516 D 536232 CDS YP_002803724.1 226948633 7765344 complement(1587228..1587500) 1 NC_012563.1 hypothetical protein 1587500 7765344 CLM_1528 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803724.1 1587228 R 536232 CDS YP_002803725.1 226948634 7764655 1587997..1589715 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF06875; methyl-accepting chemotaxis protein 1589715 7764655 CLM_1529 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002803725.1 1587997 D 536232 CDS YP_002803726.1 226948635 7764586 1590122..1591711 1 NC_012563.1 identified by match to protein family HMM PF00496; peptide ABC transporter substrate-binding protein 1591711 7764586 CLM_1530 Clostridium botulinum A2 str. Kyoto peptide ABC transporter substrate-binding protein YP_002803726.1 1590122 D 536232 CDS YP_002803727.1 226948636 7767777 1591708..1592664 1 NC_012563.1 identified by match to protein family HMM PF00528; peptide ABC transporter permease 1592664 7767777 CLM_1531 Clostridium botulinum A2 str. Kyoto peptide ABC transporter permease YP_002803727.1 1591708 D 536232 CDS YP_002803728.1 226948637 7766881 1592673..1593473 1 NC_012563.1 identified by match to protein family HMM PF00528; peptide ABC transporter permease 1593473 7766881 CLM_1532 Clostridium botulinum A2 str. Kyoto peptide ABC transporter permease YP_002803728.1 1592673 D 536232 CDS YP_002803729.1 226948638 7766595 1593572..1594366 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00005; peptide/opine/nickel uptake ABC transporter 1594366 7766595 CLM_1533 Clostridium botulinum A2 str. Kyoto peptide/opine/nickel uptake ABC transporter YP_002803729.1 1593572 D 536232 CDS YP_002803730.1 226948639 7765325 1594360..1595172 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00005; peptide/opine/nickel uptake ABC transporter 1595172 7765325 CLM_1534 Clostridium botulinum A2 str. Kyoto peptide/opine/nickel uptake ABC transporter YP_002803730.1 1594360 D 536232 CDS YP_002803731.1 226948640 7766475 1595639..1596151 1 NC_012563.1 putative lipoprotein 1596151 7766475 CLM_1535 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002803731.1 1595639 D 536232 CDS YP_002803732.1 226948641 7764900 complement(1596444..1597232) 1 NC_012563.1 identified by match to protein family HMM PF00950; manganese/zinc/iron chelate uptake ABC transporter permease 1597232 7764900 CLM_1536 Clostridium botulinum A2 str. Kyoto manganese/zinc/iron chelate uptake ABC transporter permease YP_002803732.1 1596444 R 536232 CDS YP_002803733.1 226948642 7765771 complement(1597232..1597885) 1 NC_012563.1 identified by match to protein family HMM PF00005; manganese/zinc/iron chelate uptake ABC transporter ATP-binding protein 1597885 7765771 CLM_1537 Clostridium botulinum A2 str. Kyoto manganese/zinc/iron chelate uptake ABC transporter ATP-binding protein YP_002803733.1 1597232 R 536232 CDS YP_002803734.1 226948643 7765951 1598106..1599044 1 NC_012563.1 identified by match to protein family HMM PF01297; manganese/zinc/iron chelate uptake ABC transporter substrate-binding protein 1599044 7765951 CLM_1538 Clostridium botulinum A2 str. Kyoto manganese/zinc/iron chelate uptake ABC transporter substrate-binding protein YP_002803734.1 1598106 D 536232 CDS YP_002803735.1 226948644 7766807 complement(1599158..1599649) 1 NC_012563.1 hypothetical protein 1599649 7766807 CLM_1539 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803735.1 1599158 R 536232 CDS YP_002803736.1 226948645 7767394 1600252..1602018 1 NC_012563.1 identified by match to protein family HMM PF00271; helicase domain-containing protein 1602018 7767394 CLM_1540 Clostridium botulinum A2 str. Kyoto helicase domain-containing protein YP_002803736.1 1600252 D 536232 CDS YP_002803737.1 226948646 7764272 1602153..1602701 1 NC_012563.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; GGDEF domain-containing protein 1602701 7764272 CLM_1541 Clostridium botulinum A2 str. Kyoto GGDEF domain-containing protein YP_002803737.1 1602153 D 536232 CDS YP_002803738.1 226948647 7764540 1603614..1604621 1 NC_012563.1 putative lipoprotein 1604621 7764540 CLM_1542 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002803738.1 1603614 D 536232 CDS YP_002803739.1 226948648 7766462 1604593..1605354 1 NC_012563.1 identified by match to protein family HMM PF00528; putative ABC transporter permease 1605354 7766462 CLM_1543 Clostridium botulinum A2 str. Kyoto putative ABC transporter permease YP_002803739.1 1604593 D 536232 CDS YP_002803740.1 226948649 7765841 1605494..1606093 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1606093 7765841 CLM_1544 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803740.1 1605494 D 536232 CDS YP_002803741.1 226948650 7764777 1606372..1606845 1 NC_012563.1 identified by match to protein family HMM PF01475; Fur family transcriptional regulator 1606845 7764777 CLM_1545 Clostridium botulinum A2 str. Kyoto Fur family transcriptional regulator YP_002803741.1 1606372 D 536232 CDS YP_002803742.1 226948651 7768099 1606815..1607288 1 NC_012563.1 identified by match to protein family HMM PF02001; hypothetical protein 1607288 7768099 CLM_1546 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803742.1 1606815 D 536232 CDS YP_002803743.1 226948652 7767508 1607415..1608686 1 NC_012563.1 identified by match to protein family HMM PF00246; match to protein family HMM PF01471; match to protein family HMM PF01476; zinc carboxypeptidase family protein 1608686 7767508 CLM_1547 Clostridium botulinum A2 str. Kyoto zinc carboxypeptidase family protein YP_002803743.1 1607415 D 536232 CDS YP_002803744.1 226948653 7766062 1608731..1608847 1 NC_012563.1 hypothetical protein 1608847 7766062 CLM_1548 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803744.1 1608731 D 536232 CDS YP_002803745.1 226948654 7765208 1608979..1610016 1 NC_012563.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 1610016 rnz 7765208 rnz Clostridium botulinum A2 str. Kyoto ribonuclease Z YP_002803745.1 1608979 D 536232 CDS YP_002803746.1 226948655 7764621 1610362..1611681 1 NC_012563.1 identified by match to protein family HMM PF00324; amino acid permease family protein 1611681 7764621 CLM_1550 Clostridium botulinum A2 str. Kyoto amino acid permease family protein YP_002803746.1 1610362 D 536232 CDS YP_002803747.1 226948656 7766917 1611826..1612203 1 NC_012563.1 identified by match to protein family HMM PF08000; hypothetical protein 1612203 7766917 CLM_1551 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803747.1 1611826 D 536232 CDS YP_002803748.1 226948657 7766478 1612375..1613532 1 NC_012563.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730; sensor histidine kinase 1613532 7766478 CLM_1552 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803748.1 1612375 D 536232 CDS YP_002803749.1 226948658 7766485 1613766..1614419 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family DNA-binding response regulator 1614419 7766485 CLM_1553 Clostridium botulinum A2 str. Kyoto LuxR family DNA-binding response regulator YP_002803749.1 1613766 D 536232 CDS YP_002803750.1 226948659 7766334 1614822..1615760 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1615760 7766334 CLM_1554 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002803750.1 1614822 D 536232 CDS YP_002803751.1 226948660 7767172 1615866..1617044 1 NC_012563.1 putative ABC transporter permease 1617044 7767172 CLM_1555 Clostridium botulinum A2 str. Kyoto putative ABC transporter permease YP_002803751.1 1615866 D 536232 CDS YP_002803752.1 226948661 7764682 1617046..1618146 1 NC_012563.1 identified by match to protein family HMM PF01061; hypothetical protein 1618146 7764682 CLM_1556 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803752.1 1617046 D 536232 CDS YP_002803753.1 226948662 7765517 1618150..1618395 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1618395 7765517 CLM_1557 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803753.1 1618150 D 536232 CDS YP_002803754.1 226948663 7766900 complement(1618762..1619313) 1 NC_012563.1 identified by match to protein family HMM PF00881; nitroreductase family protein 1619313 7766900 CLM_1559 Clostridium botulinum A2 str. Kyoto nitroreductase family protein YP_002803754.1 1618762 R 536232 CDS YP_002803755.1 226948664 7764735 complement(1619871..1620362) 1 NC_012563.1 hypothetical protein 1620362 7764735 CLM_1560 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803755.1 1619871 R 536232 CDS YP_002803756.1 226948665 7765886 complement(1620530..1620733) 1 NC_012563.1 identified by match to protein family HMM PF00313; major cold shock protein 1620733 7765886 CLM_1561 Clostridium botulinum A2 str. Kyoto major cold shock protein YP_002803756.1 1620530 R 536232 CDS YP_002803757.1 226948666 7767011 1621000..1622463 1 NC_012563.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893; aminoacyl-histidine dipeptidase 1622463 pepD 7767011 pepD Clostridium botulinum A2 str. Kyoto aminoacyl-histidine dipeptidase YP_002803757.1 1621000 D 536232 CDS YP_002803758.1 226948667 7766771 1622521..1623414 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; TPR domain-containing protein 1623414 7766771 CLM_1563 Clostridium botulinum A2 str. Kyoto TPR domain-containing protein YP_002803758.1 1622521 D 536232 CDS YP_002803759.1 226948668 7767884 1623680..1624516 1 NC_012563.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1624516 pdxK 7767884 pdxK Clostridium botulinum A2 str. Kyoto pyridoxamine kinase YP_002803759.1 1623680 D 536232 CDS YP_002803760.1 226948669 7764752 complement(1624805..1625443) 1 NC_012563.1 identified by match to protein family HMM PF01625; putative methionine-S-sulfoxide reductase 1625443 7764752 CLM_1565 Clostridium botulinum A2 str. Kyoto putative methionine-S-sulfoxide reductase YP_002803760.1 1624805 R 536232 CDS YP_002803761.1 226948670 7765619 1626259..1627023 1 NC_012563.1 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 1627023 7765619 CLM_1566 Clostridium botulinum A2 str. Kyoto peptide ABC transporter ATP-binding protein YP_002803761.1 1626259 D 536232 CDS YP_002803762.1 226948671 7766507 1627010..1628899 1 NC_012563.1 identified by match to protein family HMM PF02687; peptide ABC transporter permease 1628899 7766507 CLM_1567 Clostridium botulinum A2 str. Kyoto peptide ABC transporter permease YP_002803762.1 1627010 D 536232 CDS YP_002803763.1 226948672 7767383 1629076..1629573 1 NC_012563.1 hypothetical protein 1629573 7767383 CLM_1568 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803763.1 1629076 D 536232 CDS YP_002803764.1 226948673 7764317 1630016..1630717 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 1630717 7764317 CLM_1569 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002803764.1 1630016 D 536232 CDS YP_002803765.1 226948674 7767029 1630719..1631696 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 1631696 7767029 CLM_1570 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002803765.1 1630719 D 536232 CDS YP_002803766.1 226948675 7765051 1631770..1632525 1 NC_012563.1 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 1632525 7765051 CLM_1571 Clostridium botulinum A2 str. Kyoto peptide ABC transporter ATP-binding protein YP_002803766.1 1631770 D 536232 CDS YP_002803767.1 226948676 7767724 1632515..1634323 1 NC_012563.1 peptide ABC transporter permease 1634323 7767724 CLM_1572 Clostridium botulinum A2 str. Kyoto peptide ABC transporter permease YP_002803767.1 1632515 D 536232 CDS YP_002803768.1 226948677 7766788 1634392..1635114 1 NC_012563.1 hypothetical protein 1635114 7766788 CLM_1573 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803768.1 1634392 D 536232 CDS YP_002803769.1 226948678 7764800 1636878..1638056 1 NC_012563.1 identified by match to protein family HMM PF00155; class I/II aminotransferase 1638056 7764800 CLM_1576 Clostridium botulinum A2 str. Kyoto class I/II aminotransferase YP_002803769.1 1636878 D 536232 CDS YP_002803770.1 226948679 7768011 1638253..1639071 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 1639071 7768011 CLM_1577 Clostridium botulinum A2 str. Kyoto amino acid ABC transporter substrate-binding protein YP_002803770.1 1638253 D 536232 CDS YP_002803771.1 226948680 7767103 1639084..1639749 1 NC_012563.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 1639749 7767103 CLM_1578 Clostridium botulinum A2 str. Kyoto amino acid ABC transporter permease YP_002803771.1 1639084 D 536232 CDS YP_002803772.1 226948681 7765240 1639768..1640505 1 NC_012563.1 identified by match to protein family HMM PF00005; polar amino acid uptake family ABC transporter ATP-binding protein 1640505 7765240 CLM_1579 Clostridium botulinum A2 str. Kyoto polar amino acid uptake family ABC transporter ATP-binding protein YP_002803772.1 1639768 D 536232 CDS YP_002803773.1 226948682 7764403 1640931..1641149 1 NC_012563.1 identified by match to protein family HMM PF01381; putative DNA-binding protein 1641149 7764403 CLM_1580 Clostridium botulinum A2 str. Kyoto putative DNA-binding protein YP_002803773.1 1640931 D 536232 CDS YP_002803774.1 226948683 7764783 complement(1641348..1642622) 1 NC_012563.1 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase family protein 1642622 7764783 CLM_1581 Clostridium botulinum A2 str. Kyoto D-alanyl-D-alanine carboxypeptidase family protein YP_002803774.1 1641348 R 536232 CDS YP_002803775.1 226948684 7766646 1642921..1643544 1 NC_012563.1 identified by match to protein family HMM PF00293; pyrophosphatase, MutT/nudix family 1643544 7766646 CLM_1582 Clostridium botulinum A2 str. Kyoto pyrophosphatase, MutT/nudix family YP_002803775.1 1642921 D 536232 CDS YP_002803776.1 226948685 7765067 complement(1643595..1643942) 1 NC_012563.1 hypothetical protein 1643942 7765067 CLM_1583 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803776.1 1643595 R 536232 CDS YP_002803777.1 226948686 7765910 1644288..1645451 1 NC_012563.1 identified by match to protein family HMM PF00465; NADH-dependent butanol dehydrogenase 1645451 7765910 CLM_1584 Clostridium botulinum A2 str. Kyoto NADH-dependent butanol dehydrogenase YP_002803777.1 1644288 D 536232 CDS YP_002803778.1 226948687 7767332 1645835..1646059 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1646059 7767332 CLM_1585 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803778.1 1645835 D 536232 CDS YP_002803779.1 226948688 7764245 1646232..1647752 1 NC_012563.1 identified by match to protein family HMM PF03600; match to protein family HMM PF03606; match to protein family HMM PF06808; C4-dicarboxylate transporter 1647752 7764245 CLM_1586 Clostridium botulinum A2 str. Kyoto C4-dicarboxylate transporter YP_002803779.1 1646232 D 536232 CDS YP_002803780.1 226948689 7764664 complement(1647891..1649372) 1 NC_012563.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1649372 7764664 CLM_1587 Clostridium botulinum A2 str. Kyoto nicotinate phosphoribosyltransferase YP_002803780.1 1647891 R 536232 CDS YP_002803781.1 226948690 7765547 1649828..1650634 1 NC_012563.1 identified by match to protein family HMM PF00497; polar amino acid uptake ABC transporter amino acid-binding protein 1650634 7765547 CLM_1588 Clostridium botulinum A2 str. Kyoto polar amino acid uptake ABC transporter amino acid-binding protein YP_002803781.1 1649828 D 536232 CDS YP_002803782.1 226948691 7766796 1650636..1651295 1 NC_012563.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 1651295 7766796 CLM_1589 Clostridium botulinum A2 str. Kyoto amino acid ABC transporter permease YP_002803782.1 1650636 D 536232 CDS YP_002803783.1 226948692 7767672 1651426..1651974 1 NC_012563.1 hypothetical protein 1651974 7767672 CLM_1590 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803783.1 1651426 D 536232 CDS YP_002803784.1 226948693 7766314 1652069..1654081 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1654081 7766314 CLM_1591 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803784.1 1652069 D 536232 CDS YP_002803785.1 226948694 7767630 1654432..1654734 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1654734 7767630 CLM_1592 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803785.1 1654432 D 536232 CDS YP_002803786.1 226948695 7764240 1654937..1657165 1 NC_012563.1 identified by match to protein family HMM PF02491; putative cell division protein FtsA 1657165 7764240 CLM_1593 Clostridium botulinum A2 str. Kyoto putative cell division protein FtsA YP_002803786.1 1654937 D 536232 CDS YP_002803787.1 226948696 7765845 1657253..1658431 1 NC_012563.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; amidohydrolase family protein 1658431 7765845 CLM_1594 Clostridium botulinum A2 str. Kyoto amidohydrolase family protein YP_002803787.1 1657253 D 536232 CDS YP_002803788.1 226948697 7765524 1658487..1659338 1 NC_012563.1 identified by match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase 1659338 7765524 CLM_1595 Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase YP_002803788.1 1658487 D 536232 CDS YP_002803789.1 226948698 7767684 1659999..1660952 1 NC_012563.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; RluA family pseudouridine synthase 1660952 7767684 CLM_1596 Clostridium botulinum A2 str. Kyoto RluA family pseudouridine synthase YP_002803789.1 1659999 D 536232 CDS YP_002803790.1 226948699 7767252 1660984..1662591 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023; stage V sporulation protein B 1662591 spoVB 7767252 spoVB Clostridium botulinum A2 str. Kyoto stage V sporulation protein B YP_002803790.1 1660984 D 536232 CDS YP_002803791.1 226948700 7764421 complement(1662628..1664133) 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM TIGR02900; stage V sporulation protein B 1664133 spoVB 7764421 spoVB Clostridium botulinum A2 str. Kyoto stage V sporulation protein B YP_002803791.1 1662628 R 536232 CDS YP_002803792.1 226948701 7767001 1664465..1665028 1 NC_012563.1 hypothetical protein 1665028 7767001 CLM_1599 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803792.1 1664465 D 536232 CDS YP_002803793.1 226948702 7768086 complement(1665049..1665456) 1 NC_012563.1 hypothetical protein 1665456 7768086 CLM_1600 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803793.1 1665049 R 536232 CDS YP_002803794.1 226948703 7764718 1666555..1667754 1 NC_012563.1 identified by match to protein family HMM PF00465; iron-containing alcohol dehydrogenase 1667754 7764718 CLM_1601 Clostridium botulinum A2 str. Kyoto iron-containing alcohol dehydrogenase YP_002803794.1 1666555 D 536232 CDS YP_002803795.1 226948704 7765860 1668115..1670433 1 NC_012563.1 identified by match to protein family HMM PF05362; ATP-dependent protease 1670433 7765860 CLM_1602 Clostridium botulinum A2 str. Kyoto ATP-dependent protease YP_002803795.1 1668115 D 536232 CDS YP_002803796.1 226948705 7764284 complement(1671777..1673495) 1 NC_012563.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; thermolysin metallopeptidase 1673495 npr 7764284 npr Clostridium botulinum A2 str. Kyoto thermolysin metallopeptidase YP_002803796.1 1671777 R 536232 CDS YP_002803797.1 226948706 7764991 complement(1673632..1675410) 1 NC_012563.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; thermolysin metallopeptidase 1675410 npr 7764991 npr Clostridium botulinum A2 str. Kyoto thermolysin metallopeptidase YP_002803797.1 1673632 R 536232 CDS YP_002803798.1 226948707 7766833 complement(1675527..1677311) 1 NC_012563.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; thermolysin metallopeptidase 1677311 npr 7766833 npr Clostridium botulinum A2 str. Kyoto thermolysin metallopeptidase YP_002803798.1 1675527 R 536232 CDS YP_002803799.1 226948708 7765691 complement(1677431..1679176) 1 NC_012563.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; thermolysin metallopeptidase 1679176 npr 7765691 npr Clostridium botulinum A2 str. Kyoto thermolysin metallopeptidase YP_002803799.1 1677431 R 536232 CDS YP_002803800.1 226948709 7764613 complement(1679297..1681036) 1 NC_012563.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; bacillolysin 1681036 7764613 CLM_1609 Clostridium botulinum A2 str. Kyoto bacillolysin YP_002803800.1 1679297 R 536232 CDS YP_002803801.1 226948710 7767461 complement(1681639..1682475) 1 NC_012563.1 identified by match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; nicotinate-nucleotide diphosphorylase 1682475 nadC 7767461 nadC Clostridium botulinum A2 str. Kyoto nicotinate-nucleotide diphosphorylase YP_002803801.1 1681639 R 536232 CDS YP_002803802.1 226948711 7765482 complement(1682456..1683757) 1 NC_012563.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 1683757 nadB 7765482 nadB Clostridium botulinum A2 str. Kyoto L-aspartate oxidase YP_002803802.1 1682456 R 536232 CDS YP_002803803.1 226948712 7764443 complement(1683760..1684674) 1 NC_012563.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1684674 nadA 7764443 nadA Clostridium botulinum A2 str. Kyoto quinolinate synthetase YP_002803803.1 1683760 R 536232 CDS YP_002803804.1 226948713 7767273 1685046..1685546 1 NC_012563.1 hypothetical protein 1685546 7767273 CLM_1613 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803804.1 1685046 D 536232 CDS YP_002803805.1 226948714 7765969 complement(1685563..1686612) 1 NC_012563.1 identified by match to protein family HMM PF00589; phage integrase 1686612 7765969 CLM_1614 Clostridium botulinum A2 str. Kyoto phage integrase YP_002803805.1 1685563 R 536232 CDS YP_002803806.1 226948715 7765172 complement(1686599..1686820) 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 1686820 7765172 CLM_1615 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002803806.1 1686599 R 536232 CDS YP_002803807.1 226948716 7765899 1686908..1687036 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1687036 7765899 CLM_1617 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803807.1 1686908 D 536232 CDS YP_002803808.1 226948717 7767778 complement(1687007..1687369) 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 1687369 7767778 CLM_1616 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002803808.1 1687007 R 536232 CDS YP_002803809.1 226948718 7765066 1687815..1688015 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 1688015 7765066 CLM_1618 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002803809.1 1687815 D 536232 CDS YP_002803810.1 226948719 7766803 1688016..1688717 1 NC_012563.1 identified by match to protein family HMM PF09669; phage regulatory protein, Rha family 1688717 7766803 CLM_1619 Clostridium botulinum A2 str. Kyoto phage regulatory protein, Rha family YP_002803810.1 1688016 D 536232 CDS YP_002803811.1 226948720 7766445 1688718..1688879 1 NC_012563.1 hypothetical protein 1688879 7766445 CLM_1620 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803811.1 1688718 D 536232 CDS YP_002803812.1 226948721 7765559 1688892..1689032 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1689032 7765559 CLM_1621 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803812.1 1688892 D 536232 CDS YP_002803813.1 226948722 7764558 1689035..1689229 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1689229 7764558 CLM_1622 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803813.1 1689035 D 536232 CDS YP_002803814.1 226948723 7767378 1689245..1689442 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1689442 7767378 CLM_1623 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803814.1 1689245 D 536232 CDS YP_002803815.1 226948724 7766945 1689456..1689599 1 NC_012563.1 phage protein 1689599 7766945 CLM_1624 Clostridium botulinum A2 str. Kyoto phage protein YP_002803815.1 1689456 D 536232 CDS YP_002803816.1 226948725 7766017 1689592..1689759 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1689759 7766017 CLM_1625 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803816.1 1689592 D 536232 CDS YP_002803817.1 226948726 7764444 1689762..1690019 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative; hypothetical protein 1690019 7764444 CLM_1626 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803817.1 1689762 D 536232 CDS YP_002803818.1 226948727 7767583 1690068..1690229 1 NC_012563.1 hypothetical protein 1690229 7767583 CLM_1627 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803818.1 1690068 D 536232 CDS YP_002803819.1 226948728 7767585 1690207..1690518 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1690518 7767585 CLM_1628 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803819.1 1690207 D 536232 CDS YP_002803820.1 226948729 7766416 1690518..1690739 1 NC_012563.1 hypothetical protein 1690739 7766416 CLM_1629 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803820.1 1690518 D 536232 CDS YP_002803821.1 226948730 7764843 1690872..1691369 1 NC_012563.1 identified by match to protein family HMM PF07211; phage protein 1691369 7764843 CLM_1631 Clostridium botulinum A2 str. Kyoto phage protein YP_002803821.1 1690872 D 536232 CDS YP_002803822.1 226948731 7767760 1691369..1691998 1 NC_012563.1 identified by match to protein family HMM PF04404; essential recombination function protein 1691998 7767760 CLM_1632 Clostridium botulinum A2 str. Kyoto essential recombination function protein YP_002803822.1 1691369 D 536232 CDS YP_002803823.1 226948732 7766091 1692000..1692284 1 NC_012563.1 hypothetical protein 1692284 7766091 CLM_1633 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803823.1 1692000 D 536232 CDS YP_002803824.1 226948733 7764283 1692295..1693182 1 NC_012563.1 identified by match to protein family HMM PF09681; match to protein family HMM TIGR01714; putative phage replisome organizer 1693182 7764283 CLM_1634 Clostridium botulinum A2 str. Kyoto putative phage replisome organizer YP_002803824.1 1692295 D 536232 CDS YP_002803825.1 226948734 7768062 1693523..1693882 1 NC_012563.1 hypothetical protein 1693882 7768062 CLM_1635 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803825.1 1693523 D 536232 CDS YP_002803826.1 226948735 7766889 1693895..1694449 1 NC_012563.1 hypothetical protein 1694449 7766889 CLM_1636 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803826.1 1693895 D 536232 CDS YP_002803827.1 226948736 7765777 1694452..1694640 1 NC_012563.1 hypothetical protein 1694640 7765777 CLM_1637 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803827.1 1694452 D 536232 CDS YP_002803828.1 226948737 7764688 1694652..1694930 1 NC_012563.1 hypothetical protein 1694930 7764688 CLM_1638 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803828.1 1694652 D 536232 CDS YP_002803829.1 226948738 7768050 1694978..1695697 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1695697 7768050 CLM_1639 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803829.1 1694978 D 536232 CDS YP_002803830.1 226948739 7767017 1695741..1695917 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1695917 7767017 CLM_1640 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803830.1 1695741 D 536232 CDS YP_002803831.1 226948740 7765305 1695932..1696120 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1696120 7765305 CLM_1641 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803831.1 1695932 D 536232 CDS YP_002803832.1 226948741 7764254 1696181..1696294 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1696294 7764254 CLM_1642 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803832.1 1696181 D 536232 CDS YP_002803833.1 226948742 7767554 1696366..1696551 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1696551 7767554 CLM_1643 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803833.1 1696366 D 536232 CDS YP_002803834.1 226948743 7766472 1696590..1696784 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1696784 7766472 CLM_1644 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803834.1 1696590 D 536232 CDS YP_002803835.1 226948744 7767923 1696913..1697962 1 NC_012563.1 hypothetical protein 1697962 7767923 CLM_1645 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803835.1 1696913 D 536232 CDS YP_002803836.1 226948745 7764906 1698069..1698782 1 NC_012563.1 hypothetical protein 1698782 7764906 CLM_1646 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803836.1 1698069 D 536232 CDS YP_002803837.1 226948746 7764204 1698779..1698964 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1698964 7764204 CLM_1647 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803837.1 1698779 D 536232 CDS YP_002803838.1 226948747 7765254 1698951..1699100 1 NC_012563.1 hypothetical protein 1699100 7765254 CLM_1648 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803838.1 1698951 D 536232 CDS YP_002803839.1 226948748 7766662 1699112..1699282 1 NC_012563.1 hypothetical protein 1699282 7766662 CLM_1649 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803839.1 1699112 D 536232 CDS YP_002803840.1 226948749 7767494 1699272..1699658 1 NC_012563.1 hypothetical protein 1699658 7767494 CLM_1650 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803840.1 1699272 D 536232 CDS YP_002803841.1 226948750 7764816 1699918..1700130 1 NC_012563.1 hypothetical protein 1700130 7764816 CLM_1651 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803841.1 1699918 D 536232 CDS YP_002803842.1 226948751 7765694 1700131..1700736 1 NC_012563.1 identified by match to protein family HMM PF00589; phage integrase family protein 1700736 7765694 CLM_1652 Clostridium botulinum A2 str. Kyoto phage integrase family protein YP_002803842.1 1700131 D 536232 CDS YP_002803843.1 226948752 7765014 1701034..1701531 1 NC_012563.1 hypothetical protein 1701531 7765014 CLM_1653 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803843.1 1701034 D 536232 CDS YP_002803844.1 226948753 7765679 1701586..1701948 1 NC_012563.1 identified by match to protein family HMM PF01844; HNH endonuclease domain-containing protein 1701948 7765679 CLM_1654 Clostridium botulinum A2 str. Kyoto HNH endonuclease domain-containing protein YP_002803844.1 1701586 D 536232 CDS YP_002803845.1 226948754 7767456 1702109..1702591 1 NC_012563.1 identified by match to protein family HMM PF05119; match to protein family HMM TIGR01558; phage terminase small subunit, P27 family 1702591 7767456 CLM_1655 Clostridium botulinum A2 str. Kyoto phage terminase small subunit, P27 family YP_002803845.1 1702109 D 536232 CDS YP_002803846.1 226948755 7766235 1702591..1704333 1 NC_012563.1 identified by match to protein family HMM PF03354; putative phage terminase large subunit 1704333 7766235 CLM_1656 Clostridium botulinum A2 str. Kyoto putative phage terminase large subunit YP_002803846.1 1702591 D 536232 CDS YP_002803847.1 226948756 7764235 1704345..1705601 1 NC_012563.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; phage portal protein, HK97 family 1705601 7764235 CLM_1657 Clostridium botulinum A2 str. Kyoto phage portal protein, HK97 family YP_002803847.1 1704345 D 536232 CDS YP_002803848.1 226948757 7767552 1705588..1706349 1 NC_012563.1 identified by match to protein family HMM PF00574; serine protease 1706349 7767552 CLM_1658 Clostridium botulinum A2 str. Kyoto serine protease YP_002803848.1 1705588 D 536232 CDS YP_002803849.1 226948758 7766948 1706388..1707563 1 NC_012563.1 identified by match to protein family HMM PF05065; match to protein family HMM TIGR01554; phage major capsid protein, HK97 family 1707563 7766948 CLM_1659 Clostridium botulinum A2 str. Kyoto phage major capsid protein, HK97 family YP_002803849.1 1706388 D 536232 CDS YP_002803850.1 226948759 7765310 1707608..1707865 1 NC_012563.1 identified by match to protein family HMM PF05135; match to protein family HMM TIGR01560; hypothetical protein 1707865 7765310 CLM_1660 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803850.1 1707608 D 536232 CDS YP_002803851.1 226948760 7766130 1707884..1708219 1 NC_012563.1 identified by similarity to GB:ABR48571.1; hypothetical protein 1708219 7766130 CLM_1661 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803851.1 1707884 D 536232 CDS YP_002803852.1 226948761 7764942 1708229..1708438 1 NC_012563.1 hypothetical protein 1708438 7764942 CLM_1662 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803852.1 1708229 D 536232 CDS YP_002803853.1 226948762 7767821 1708441..1708854 1 NC_012563.1 hypothetical protein 1708854 7767821 CLM_1663 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803853.1 1708441 D 536232 CDS YP_002803854.1 226948763 7766671 1708915..1709340 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1709340 7766671 CLM_1664 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803854.1 1708915 D 536232 CDS YP_002803855.1 226948764 7767278 1709543..1709833 1 NC_012563.1 hypothetical protein 1709833 7767278 CLM_1665 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803855.1 1709543 D 536232 CDS YP_002803856.1 226948765 7764252 1709838..1710923 1 NC_012563.1 hypothetical protein 1710923 7764252 CLM_1666 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803856.1 1709838 D 536232 CDS YP_002803857.1 226948766 7765287 1710934..1711362 1 NC_012563.1 identified by match to protein family HMM PF09393; hypothetical protein 1711362 7765287 CLM_1667 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803857.1 1710934 D 536232 CDS YP_002803858.1 226948767 7766664 1711378..1711797 1 NC_012563.1 hypothetical protein 1711797 7766664 CLM_1668 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803858.1 1711378 D 536232 CDS YP_002803859.1 226948768 7764770 1711866..1711997 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1711997 7764770 CLM_1669 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803859.1 1711866 D 536232 CDS YP_002803860.1 226948769 7765885 1712033..1714663 1 NC_012563.1 identified by match to protein family HMM TIGR01760; phage tail tape measure protein, TP901 family, core region 1714663 7765885 CLM_1670 Clostridium botulinum A2 str. Kyoto phage tail tape measure protein, TP901 family, core region YP_002803860.1 1712033 D 536232 CDS YP_002803861.1 226948770 7767043 1714710..1715141 1 NC_012563.1 identified by similarity to GB:ABR48580.1; hypothetical protein 1715141 7767043 CLM_1671 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803861.1 1714710 D 536232 CDS YP_002803862.1 226948771 7767948 1715141..1716073 1 NC_012563.1 hypothetical protein 1716073 7767948 CLM_1672 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803862.1 1715141 D 536232 CDS YP_002803863.1 226948772 7764791 1716084..1716401 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1716401 7764791 CLM_1673 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803863.1 1716084 D 536232 CDS YP_002803864.1 226948773 7765853 1716413..1716850 1 NC_012563.1 hypothetical protein 1716850 7765853 CLM_1674 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803864.1 1716413 D 536232 CDS YP_002803865.1 226948774 7767501 1716862..1717971 1 NC_012563.1 identified by match to protein family HMM PF04865; hypothetical protein 1717971 7767501 CLM_1675 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803865.1 1716862 D 536232 CDS YP_002803866.1 226948775 7767900 1717983..1718513 1 NC_012563.1 hypothetical protein 1718513 7767900 CLM_1676 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803866.1 1717983 D 536232 CDS YP_002803867.1 226948776 7767047 1718524..1719330 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1719330 7767047 CLM_1677 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803867.1 1718524 D 536232 CDS YP_002803868.1 226948777 7766125 1719346..1719651 1 NC_012563.1 hypothetical protein 1719651 7766125 CLM_1678 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803868.1 1719346 D 536232 CDS YP_002803869.1 226948778 7764978 1719667..1719852 1 NC_012563.1 hypothetical protein 1719852 7764978 CLM_1679 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803869.1 1719667 D 536232 CDS YP_002803870.1 226948779 7767321 1719940..1720143 1 NC_012563.1 identified by similarity to SP:P15936; bacteriocin UviB 1720143 7767321 CLM_1680 Clostridium botulinum A2 str. Kyoto bacteriocin UviB YP_002803870.1 1719940 D 536232 CDS YP_002803871.1 226948780 7766603 1720145..1720318 1 NC_012563.1 hypothetical protein 1720318 7766603 CLM_1681 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803871.1 1720145 D 536232 CDS YP_002803872.1 226948781 7765447 1720361..1721119 1 NC_012563.1 identified by match to protein family HMM PF01520; bacteriophage endolysin 1721119 7765447 CLM_1682 Clostridium botulinum A2 str. Kyoto bacteriophage endolysin YP_002803872.1 1720361 D 536232 CDS YP_002803873.1 226948782 7765784 1721443..1721595 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1721595 7765784 CLM_1683 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803873.1 1721443 D 536232 CDS YP_002803874.1 226948783 7764714 1721582..1721764 1 NC_012563.1 hypothetical protein 1721764 7764714 CLM_1684 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803874.1 1721582 D 536232 CDS YP_002803875.1 226948784 7765590 1721775..1722020 1 NC_012563.1 putative lipoprotein 1722020 7765590 CLM_1685 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002803875.1 1721775 D 536232 CDS YP_002803876.1 226948785 7764453 1722165..1722671 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1722671 7764453 CLM_1686 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803876.1 1722165 D 536232 CDS YP_002803877.1 226948786 7767337 1722828..1723316 1 NC_012563.1 hypothetical protein 1723316 7767337 CLM_1687 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803877.1 1722828 D 536232 CDS YP_002803878.1 226948787 7766386 complement(1723413..1724051) 1 NC_012563.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin III 1724051 hlyIII 7766386 hlyIII Clostridium botulinum A2 str. Kyoto hemolysin III YP_002803878.1 1723413 R 536232 CDS YP_002803879.1 226948788 7766143 complement(1724172..1725269) 1 NC_012563.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1725269 ychF 7766143 ychF Clostridium botulinum A2 str. Kyoto GTP-dependent nucleic acid-binding protein EngD YP_002803879.1 1724172 R 536232 CDS YP_002803880.1 226948789 7765029 1725963..1726433 1 NC_012563.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 1726433 mraZ 7765029 mraZ Clostridium botulinum A2 str. Kyoto cell division protein MraZ YP_002803880.1 1725963 D 536232 CDS YP_002803881.1 226948790 7767886 1726513..1727442 1 NC_012563.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 1727442 mraW 7767886 mraW Clostridium botulinum A2 str. Kyoto S-adenosyl-methyltransferase MraW YP_002803881.1 1726513 D 536232 CDS YP_002803882.1 226948791 7766838 1727524..1728027 1 NC_012563.1 putative cell division protein FtsL 1728027 7766838 CLM_1692 Clostridium botulinum A2 str. Kyoto putative cell division protein FtsL YP_002803882.1 1727524 D 536232 CDS YP_002803883.1 226948792 7766111 1728043..1730223 1 NC_012563.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793; match to protein family HMM TIGR02214; stage V sporulation protein D 1730223 7766111 CLM_1693 Clostridium botulinum A2 str. Kyoto stage V sporulation protein D YP_002803883.1 1728043 D 536232 CDS YP_002803884.1 226948793 7765008 1730453..1731904 1 NC_012563.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1731904 murE 7765008 murE Clostridium botulinum A2 str. Kyoto UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_002803884.1 1730453 D 536232 CDS YP_002803885.1 226948794 7767681 1731930..1733318 1 NC_012563.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 1733318 murF 7767681 murF Clostridium botulinum A2 str. Kyoto UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_002803885.1 1731930 D 536232 CDS YP_002803886.1 226948795 7767557 1733354..1734307 1 NC_012563.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1734307 mraY 7767557 mraY Clostridium botulinum A2 str. Kyoto phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002803886.1 1733354 D 536232 CDS YP_002803887.1 226948796 7766055 1734386..1735498 1 NC_012563.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02614; match to protein family HMM TIGR02615; cell cycle protein, FtsW/RodA/SpoVE family 1735498 7766055 CLM_1697 Clostridium botulinum A2 str. Kyoto cell cycle protein, FtsW/RodA/SpoVE family YP_002803887.1 1734386 D 536232 CDS YP_002803888.1 226948797 7766955 1735821..1736591 1 NC_012563.1 identified by match to protein family HMM PF08478; cell division protein FtsQ 1736591 7766955 CLM_1698 Clostridium botulinum A2 str. Kyoto cell division protein FtsQ YP_002803888.1 1735821 D 536232 CDS YP_002803889.1 226948798 7767257 1736602..1737315 1 NC_012563.1 identified by match to protein family HMM PF05949; hypothetical protein 1737315 7767257 CLM_1699 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803889.1 1736602 D 536232 CDS YP_002803890.1 226948799 7765125 1737350..1737700 1 NC_012563.1 identified by match to protein family HMM PF06947; small basic protein 1737700 sbp 7765125 sbp Clostridium botulinum A2 str. Kyoto small basic protein YP_002803890.1 1737350 D 536232 CDS YP_002803891.1 226948800 7765548 1737701..1738432 1 NC_012563.1 identified by match to protein family HMM PF05949; hypothetical protein 1738432 7765548 CLM_1701 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803891.1 1737701 D 536232 CDS YP_002803892.1 226948801 7766426 1738525..1739196 1 NC_012563.1 identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044; hypothetical protein 1739196 7766426 CLM_1702 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803892.1 1738525 D 536232 CDS YP_002803893.1 226948802 7764824 1739217..1739669 1 NC_012563.1 identified by match to protein family HMM PF04472; hypothetical protein 1739669 7764824 CLM_1703 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803893.1 1739217 D 536232 CDS YP_002803894.1 226948803 7765707 1739686..1739961 1 NC_012563.1 identified by match to protein family HMM PF02325; YGGT family protein 1739961 7765707 CLM_1704 Clostridium botulinum A2 str. Kyoto YGGT family protein YP_002803894.1 1739686 D 536232 CDS YP_002803895.1 226948804 7764338 1739962..1740732 1 NC_012563.1 hypothetical protein 1740732 7764338 CLM_1705 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803895.1 1739962 D 536232 CDS YP_002803896.1 226948805 7765361 1740748..1741407 1 NC_012563.1 identified by match to protein family HMM PF05103; match to protein family HMM TIGR03544; cell-division initiation protein DivIVA 1741407 divIVA 7765361 divIVA Clostridium botulinum A2 str. Kyoto cell-division initiation protein DivIVA YP_002803896.1 1740748 D 536232 CDS YP_002803897.1 226948806 7766946 1741815..1742903 1 NC_012563.1 identified by match to protein family HMM PF01761; match to protein family HMM TIGR01357; 3-dehydroquinate synthase 1742903 aroB 7766946 aroB Clostridium botulinum A2 str. Kyoto 3-dehydroquinate synthase YP_002803897.1 1741815 D 536232 CDS YP_002803898.1 226948807 7768065 1742904..1743596 1 NC_012563.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1743596 mtnN 7768065 mtnN Clostridium botulinum A2 str. Kyoto 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002803898.1 1742904 D 536232 CDS YP_002803899.1 226948808 7767657 1743717..1744517 1 NC_012563.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; 3-deoxy-7-phosphoheptulonate synthase 1744517 aroF 7767657 aroF Clostridium botulinum A2 str. Kyoto 3-deoxy-7-phosphoheptulonate synthase YP_002803899.1 1743717 D 536232 CDS YP_002803900.1 226948809 7765805 1744684..1746012 1 NC_012563.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1746012 aroA 7765805 aroA Clostridium botulinum A2 str. Kyoto 3-phosphoshikimate 1-carboxyvinyltransferase YP_002803900.1 1744684 D 536232 CDS YP_002803901.1 226948810 7765383 1746229..1746852 1 NC_012563.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02890; putative RNA polymerase-binding protein DksA 1746852 7765383 CLM_1711 Clostridium botulinum A2 str. Kyoto putative RNA polymerase-binding protein DksA YP_002803901.1 1746229 D 536232 CDS YP_002803902.1 226948811 7766555 1747076..1747519 1 NC_012563.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1747519 lspA 7766555 lspA Clostridium botulinum A2 str. Kyoto lipoprotein signal peptidase YP_002803902.1 1747076 D 536232 CDS YP_002803903.1 226948812 7767189 1747523..1748440 1 NC_012563.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; RluA family pseudouridine synthase 1748440 7767189 CLM_1713 Clostridium botulinum A2 str. Kyoto RluA family pseudouridine synthase YP_002803903.1 1747523 D 536232 CDS YP_002803904.1 226948813 7765121 1748936..1749472 1 NC_012563.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 1749472 pyrR 7765121 pyrR Clostridium botulinum A2 str. Kyoto bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_002803904.1 1748936 D 536232 CDS YP_002803905.1 226948814 7767085 1749516..1750859 1 NC_012563.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil permease 1750859 uraA 7767085 uraA Clostridium botulinum A2 str. Kyoto uracil permease YP_002803905.1 1749516 D 536232 CDS YP_002803906.1 226948815 7765628 complement(1750927..1751052) 1 NC_012563.1 putative small multi-drug export protein 1751052 7765628 CLM_1717 Clostridium botulinum A2 str. Kyoto putative small multi-drug export protein YP_002803906.1 1750927 R 536232 CDS YP_002803907.1 226948816 7764850 1751161..1751922 1 NC_012563.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633; exodeoxyribonuclease III 1751922 xth 7764850 xth Clostridium botulinum A2 str. Kyoto exodeoxyribonuclease III YP_002803907.1 1751161 D 536232 CDS YP_002803908.1 226948817 7767345 1752146..1753288 1 NC_012563.1 identified by match to protein family HMM PF01170; putative methyltransferase 1753288 7767345 CLM_1719 Clostridium botulinum A2 str. Kyoto putative methyltransferase YP_002803908.1 1752146 D 536232 CDS YP_002803909.1 226948818 7766216 1753518..1754063 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1754063 7766216 CLM_1720 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803909.1 1753518 D 536232 CDS YP_002803910.1 226948819 7765534 1754241..1755056 1 NC_012563.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR01256; molybdate ABC transporter substrate-binding protein 1755056 modA 7765534 modA Clostridium botulinum A2 str. Kyoto molybdate ABC transporter substrate-binding protein YP_002803910.1 1754241 D 536232 CDS YP_002803911.1 226948820 7764617 1755066..1755737 1 NC_012563.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02141; molybdate ABC transporter permease 1755737 modB 7764617 modB Clostridium botulinum A2 str. Kyoto molybdate ABC transporter permease YP_002803911.1 1755066 D 536232 CDS YP_002803912.1 226948821 7767176 1756064..1756735 1 NC_012563.1 identified by match to protein family HMM PF00005; putative molybdate ABC transporter ATP-binding protein 1756735 7767176 CLM_1723 Clostridium botulinum A2 str. Kyoto putative molybdate ABC transporter ATP-binding protein YP_002803912.1 1756064 D 536232 CDS YP_002803913.1 226948822 7766315 1756789..1757358 1 NC_012563.1 hypothetical protein 1757358 7766315 CLM_1724 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803913.1 1756789 D 536232 CDS YP_002803914.1 226948823 7766962 1757706..1758629 1 NC_012563.1 identified by match to protein family HMM PF01734; patatin-like phospholipase family protein 1758629 7766962 CLM_1725 Clostridium botulinum A2 str. Kyoto patatin-like phospholipase family protein YP_002803914.1 1757706 D 536232 CDS YP_002803915.1 226948824 7767318 1758929..1759084 1 NC_012563.1 hypothetical protein 1759084 7767318 CLM_1726 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803915.1 1758929 D 536232 CDS YP_002803916.1 226948825 7765908 1759357..1760409 1 NC_012563.1 identified by match to protein family HMM PF01208; uroporphyrinogen decarboxylase family protein 1760409 7765908 CLM_1727 Clostridium botulinum A2 str. Kyoto uroporphyrinogen decarboxylase family protein YP_002803916.1 1759357 D 536232 CDS YP_002803917.1 226948826 7765063 1760497..1761894 1 NC_012563.1 identified by match to protein family HMM PF03553; Na+/H+ antiporter family protein 1761894 7765063 CLM_1728 Clostridium botulinum A2 str. Kyoto Na+/H+ antiporter family protein YP_002803917.1 1760497 D 536232 CDS YP_002803918.1 226948827 7766794 1762036..1763766 1 NC_012563.1 identified by match to protein family HMM PF00111; iron-sulfur cluster-binding protein 1763766 7766794 CLM_1729 Clostridium botulinum A2 str. Kyoto iron-sulfur cluster-binding protein YP_002803918.1 1762036 D 536232 CDS YP_002803919.1 226948828 7767783 1763856..1764785 1 NC_012563.1 identified by match to protein family HMM PF02492; CobW/P47K family protein 1764785 7767783 CLM_1730 Clostridium botulinum A2 str. Kyoto CobW/P47K family protein YP_002803919.1 1763856 D 536232 CDS YP_002803920.1 226948829 7767564 1764808..1765680 1 NC_012563.1 uroporphyrinogen decarboxylase family protein 1765680 7767564 CLM_1731 Clostridium botulinum A2 str. Kyoto uroporphyrinogen decarboxylase family protein YP_002803920.1 1764808 D 536232 CDS YP_002803921.1 226948830 7764471 1765706..1766368 1 NC_012563.1 identified by match to protein family HMM PF02310; match to protein family HMM PF02607; match to protein family HMM TIGR02370; dimethylamine corrinoid protein 1766368 mtbC 7764471 mtbC Clostridium botulinum A2 str. Kyoto dimethylamine corrinoid protein YP_002803921.1 1765706 D 536232 CDS YP_002803922.1 226948831 7765317 1766453..1767475 1 NC_012563.1 catalyze the formation of methyl-coenzyme M from methylcobalamin and coenzyme M; methylcobalamin:coenzyme M methyltransferase 1767475 7765317 CLM_1733 Clostridium botulinum A2 str. Kyoto methylcobalamin:coenzyme M methyltransferase YP_002803922.1 1766453 D 536232 CDS YP_002803923.1 226948832 7766188 1768422..1769492 1 NC_012563.1 identified by match to protein family HMM PF01208; uroporphyrinogen decarboxylase family protein 1769492 7766188 CLM_1734 Clostridium botulinum A2 str. Kyoto uroporphyrinogen decarboxylase family protein YP_002803923.1 1768422 D 536232 CDS YP_002803924.1 226948833 7767823 1769515..1770477 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF09383; methionine ABC transporter ATP-binding protein 1770477 7767823 CLM_1735 Clostridium botulinum A2 str. Kyoto methionine ABC transporter ATP-binding protein YP_002803924.1 1769515 D 536232 CDS YP_002803925.1 226948834 7765807 1770479..1771135 1 NC_012563.1 identified by match to protein family HMM PF00528; methionine ABC transporter permease 1771135 7765807 CLM_1736 Clostridium botulinum A2 str. Kyoto methionine ABC transporter permease YP_002803925.1 1770479 D 536232 CDS YP_002803926.1 226948835 7766743 1771279..1772097 1 NC_012563.1 identified by match to protein family HMM PF03180; NLPA family lipoprotein 1772097 7766743 CLM_1737 Clostridium botulinum A2 str. Kyoto NLPA family lipoprotein YP_002803926.1 1771279 D 536232 CDS YP_002803927.1 226948836 7767640 complement(1772188..1772757) 1 NC_012563.1 identified by match to protein family HMM PF02493; MORN repeat-containing protein 1772757 7767640 CLM_1738 Clostridium botulinum A2 str. Kyoto MORN repeat-containing protein YP_002803927.1 1772188 R 536232 CDS YP_002803928.1 226948837 7764339 1773331..1774350 1 NC_012563.1 identified by match to protein family HMM PF00724; FAD/FMN-binding family oxidoreductase 1774350 7764339 CLM_1739 Clostridium botulinum A2 str. Kyoto FAD/FMN-binding family oxidoreductase YP_002803928.1 1773331 D 536232 CDS YP_002803929.1 226948838 7765269 1774679..1775701 1 NC_012563.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 1775701 asnA 7765269 asnA Clostridium botulinum A2 str. Kyoto asparagine synthetase AsnA YP_002803929.1 1774679 D 536232 CDS YP_002803930.1 226948839 7766496 complement(1775810..1777375) 1 NC_012563.1 identified by match to protein family HMM PF00355; match to protein family HMM PF01266; FAD-dependent family oxidoreductase 1777375 7766496 CLM_1741 Clostridium botulinum A2 str. Kyoto FAD-dependent family oxidoreductase YP_002803930.1 1775810 R 536232 CDS YP_002803931.1 226948840 7767220 1777728..1779587 1 NC_012563.1 identified by match to protein family HMM PF01131; match to protein family HMM PF01751; DNA topoisomerase 1779587 7767220 CLM_1742 Clostridium botulinum A2 str. Kyoto DNA topoisomerase YP_002803931.1 1777728 D 536232 CDS YP_002803932.1 226948841 7764351 1779614..1781527 1 NC_012563.1 identified by match to protein family HMM PF00488; mutS domain-containing protein 1781527 7764351 CLM_1743 Clostridium botulinum A2 str. Kyoto mutS domain-containing protein YP_002803932.1 1779614 D 536232 CDS YP_002803933.1 226948842 7764957 1781844..1782980 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00248; aldo/keto reductase family oxidoreductase 1782980 7764957 CLM_1744 Clostridium botulinum A2 str. Kyoto aldo/keto reductase family oxidoreductase YP_002803933.1 1781844 D 536232 CDS YP_002803934.1 226948843 7766049 complement(1783038..1783529) 1 NC_012563.1 identified by match to protein family HMM PF04073; hypothetical protein 1783529 7766049 CLM_1745 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803934.1 1783038 R 536232 CDS YP_002803935.1 226948844 7765503 1783766..1784464 1 NC_012563.1 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 1784464 7765503 CLM_1746 Clostridium botulinum A2 str. Kyoto peptide ABC transporter ATP-binding protein YP_002803935.1 1783766 D 536232 CDS YP_002803936.1 226948845 7766351 1784465..1786675 1 NC_012563.1 identified by match to protein family HMM PF02687; efflux ABC transporter permease 1786675 7766351 CLM_1747 Clostridium botulinum A2 str. Kyoto efflux ABC transporter permease YP_002803936.1 1784465 D 536232 CDS YP_002803937.1 226948846 7767261 1786687..1787310 1 NC_012563.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1787310 7767261 CLM_1748 Clostridium botulinum A2 str. Kyoto TetR family transcriptional regulator YP_002803937.1 1786687 D 536232 CDS YP_002803938.1 226948847 7765145 1787672..1788223 1 NC_012563.1 hypothetical protein 1788223 7765145 CLM_1749 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803938.1 1787672 D 536232 CDS YP_002803939.1 226948848 7766005 1788236..1789333 1 NC_012563.1 identified by match to protein family HMM PF00005; carbohydrate uptake ABC transporter ATP-binding protein 1789333 7766005 CLM_1750 Clostridium botulinum A2 str. Kyoto carbohydrate uptake ABC transporter ATP-binding protein YP_002803939.1 1788236 D 536232 CDS YP_002803940.1 226948849 7766871 1789326..1790219 1 NC_012563.1 identified by match to protein family HMM PF00528; carbohydrate uptake ABC transporter permease 1790219 7766871 CLM_1751 Clostridium botulinum A2 str. Kyoto carbohydrate uptake ABC transporter permease YP_002803940.1 1789326 D 536232 CDS YP_002803941.1 226948850 7767785 1790255..1791079 1 NC_012563.1 identified by match to protein family HMM PF00528; carbohydrate uptake ABC transporter permease 1791079 7767785 CLM_1752 Clostridium botulinum A2 str. Kyoto carbohydrate uptake ABC transporter permease YP_002803941.1 1790255 D 536232 CDS YP_002803942.1 226948851 7764642 1791125..1792486 1 NC_012563.1 identified by match to protein family HMM PF01547; carbohydrate uptake ABC transporter carbohydrate-binding protein 1792486 7764642 CLM_1753 Clostridium botulinum A2 str. Kyoto carbohydrate uptake ABC transporter carbohydrate-binding protein YP_002803942.1 1791125 D 536232 CDS YP_002803943.1 226948852 7765537 complement(1792710..1793666) 1 NC_012563.1 identified by match to protein family HMM PF00056; match to protein family HMM PF02866; match to protein family HMM TIGR01771; L-lactate dehydrogenase 1793666 ldh 7765537 ldh Clostridium botulinum A2 str. Kyoto L-lactate dehydrogenase YP_002803943.1 1792710 R 536232 CDS YP_002803944.1 226948853 7766308 1794188..1794898 1 NC_012563.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 1794898 7766308 CLM_1755 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002803944.1 1794188 D 536232 CDS YP_002803945.1 226948854 7766241 complement(1795344..1795832) 1 NC_012563.1 identified by match to protein family HMM PF09719; match to protein family HMM TIGR01909; redox family protein 1795832 7766241 CLM_1756 Clostridium botulinum A2 str. Kyoto redox family protein YP_002803945.1 1795344 R 536232 CDS YP_002803946.1 226948855 7767435 1796066..1797013 1 NC_012563.1 identified by match to protein family HMM PF03595; C4-dicarboxylate transporter/malic acid transport protein 1797013 7767435 CLM_1757 Clostridium botulinum A2 str. Kyoto C4-dicarboxylate transporter/malic acid transport protein YP_002803946.1 1796066 D 536232 CDS YP_002803947.1 226948856 7764848 complement(1797085..1797162) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1797162 7764848 CLM_1758 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803947.1 1797085 R 536232 CDS YP_002803948.1 226948857 7766773 1797876..1800074 1 NC_012563.1 identified by match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF01966; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; putative sensory box-containing diguanylate cyclase 1800074 7766773 CLM_1759 Clostridium botulinum A2 str. Kyoto putative sensory box-containing diguanylate cyclase YP_002803948.1 1797876 D 536232 CDS YP_002803949.1 226948858 7765708 1800182..1800529 1 NC_012563.1 identified by match to protein family HMM PF03860; hypothetical protein 1800529 7765708 CLM_1760 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803949.1 1800182 D 536232 CDS YP_002803950.1 226948859 7764751 1800897..1802969 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 1802969 7764751 CLM_1761 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002803950.1 1800897 D 536232 CDS YP_002803951.1 226948860 7765713 1803175..1803654 1 NC_012563.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1803654 7765713 CLM_1762 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002803951.1 1803175 D 536232 CDS YP_002803952.1 226948861 7765257 1803668..1804210 1 NC_012563.1 hypothetical protein 1804210 7765257 CLM_1763 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803952.1 1803668 D 536232 CDS YP_002803953.1 226948862 7767912 complement(1804359..1804712) 1 NC_012563.1 identified by match to protein family HMM PF01638; putative transcriptional regulator 1804712 7767912 CLM_1764 Clostridium botulinum A2 str. Kyoto putative transcriptional regulator YP_002803953.1 1804359 R 536232 CDS YP_002803954.1 226948863 7767497 1805107..1805472 1 NC_012563.1 identified by match to protein family HMM PF00903; glyoxalase family protein 1805472 7767497 CLM_1765 Clostridium botulinum A2 str. Kyoto glyoxalase family protein YP_002803954.1 1805107 D 536232 CDS YP_002803955.1 226948864 7764391 1805501..1805971 1 NC_012563.1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated; methylated-DNA--protein-cysteine methyltransferase 1805971 ogt 7764391 ogt Clostridium botulinum A2 str. Kyoto methylated-DNA--protein-cysteine methyltransferase YP_002803955.1 1805501 D 536232 CDS YP_002803956.1 226948865 7764397 1805998..1807215 1 NC_012563.1 identified by match to protein family HMM PF00165; match to protein family HMM PF09370; AraC family transcriptional regulator 1807215 7764397 CLM_1767 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002803956.1 1805998 D 536232 CDS YP_002803957.1 226948866 7765985 1807380..1808588 1 NC_012563.1 identified by match to protein family HMM PF06792; hypothetical protein 1808588 7765985 CLM_1768 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803957.1 1807380 D 536232 CDS YP_002803958.1 226948867 7766409 1808613..1809443 1 NC_012563.1 identified by match to protein family HMM PF09370; hypothetical protein 1809443 7766409 CLM_1769 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803958.1 1808613 D 536232 CDS YP_002803959.1 226948868 7767598 1809833..1810945 1 NC_012563.1 identified by match to protein family HMM PF01381; putative DNA-binding protein 1810945 7767598 CLM_1770 Clostridium botulinum A2 str. Kyoto putative DNA-binding protein YP_002803959.1 1809833 D 536232 CDS YP_002803960.1 226948869 7766614 complement(1810973..1811140) 1 NC_012563.1 hypothetical protein 1811140 7766614 CLM_1771 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803960.1 1810973 R 536232 CDS YP_002803961.1 226948870 7767490 1811253..1811627 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1811627 7767490 CLM_1772 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803961.1 1811253 D 536232 CDS YP_002803962.1 226948871 7764483 1811684..1812553 1 NC_012563.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 1812553 7764483 CLM_1773 Clostridium botulinum A2 str. Kyoto cation efflux family protein YP_002803962.1 1811684 D 536232 CDS YP_002803963.1 226948872 7765587 1813039..1814442 1 NC_012563.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter 1814442 7765587 CLM_1774 Clostridium botulinum A2 str. Kyoto amino acid/peptide transporter YP_002803963.1 1813039 D 536232 CDS YP_002803964.1 226948873 7765365 1814880..1815239 1 NC_012563.1 identified by match to protein family HMM PF01325; match to protein family HMM PF02742; putative iron-dependent repressor 1815239 7765365 CLM_1775 Clostridium botulinum A2 str. Kyoto putative iron-dependent repressor YP_002803964.1 1814880 D 536232 CDS YP_002803965.1 226948874 7766465 1815337..1815744 1 NC_012563.1 hypothetical protein 1815744 7766465 CLM_1776 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803965.1 1815337 D 536232 CDS YP_002803966.1 226948875 7765007 1816125..1816979 1 NC_012563.1 identified by match to protein family HMM PF01966; match to protein family HMM PF08668; match to protein family HMM TIGR00277; HDIG domain-containing protein 1816979 7765007 CLM_1777 Clostridium botulinum A2 str. Kyoto HDIG domain-containing protein YP_002803966.1 1816125 D 536232 CDS YP_002803967.1 226948876 7764425 1817096..1817257 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1817257 7764425 CLM_1779 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803967.1 1817096 D 536232 CDS YP_002803968.1 226948877 7765097 complement(1817434..1820070) 1 NC_012563.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; P-type cation-transporting ATPase 1820070 7765097 CLM_1780 Clostridium botulinum A2 str. Kyoto P-type cation-transporting ATPase YP_002803968.1 1817434 R 536232 CDS YP_002803969.1 226948878 7765925 1820905..1821267 1 NC_012563.1 identified by match to protein family HMM PF00903; glyoxalase family protein 1821267 7765925 CLM_1782 Clostridium botulinum A2 str. Kyoto glyoxalase family protein YP_002803969.1 1820905 D 536232 CDS YP_002803970.1 226948879 7765225 complement(1821907..1822332) 1 NC_012563.1 hypothetical protein 1822332 7765225 CLM_1785 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803970.1 1821907 R 536232 CDS YP_002803971.1 226948880 7767120 1823262..1823429 1 NC_012563.1 identified by match to protein family HMM PF00196; LuxR family transcriptional regulator 1823429 7767120 CLM_1788 Clostridium botulinum A2 str. Kyoto LuxR family transcriptional regulator YP_002803971.1 1823262 D 536232 CDS YP_002803972.1 226948881 7767009 complement(1823509..1824231) 1 NC_012563.1 identified by match to protein family HMM PF06445; transcription activator, effector binding domain-containing protein 1824231 7767009 CLM_1790 Clostridium botulinum A2 str. Kyoto transcription activator, effector binding domain-containing protein YP_002803972.1 1823509 R 536232 CDS YP_002803973.1 226948882 7766104 complement(1824289..1825233) 1 NC_012563.1 identified by match to protein family HMM PF08220; match to protein family HMM PF08279; hypothetical protein 1825233 7766104 CLM_1791 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803973.1 1824289 R 536232 CDS YP_002803974.1 226948883 7767238 1825848..1826843 1 NC_012563.1 identified by match to protein family HMM PF06050; 2-hydroxyglutaryl-CoA dehydratase subunit D 1826843 7767238 CLM_1793 Clostridium botulinum A2 str. Kyoto 2-hydroxyglutaryl-CoA dehydratase subunit D YP_002803974.1 1825848 D 536232 CDS YP_002803975.1 226948884 7766400 1826960..1827721 1 NC_012563.1 identified by match to protein family HMM PF01869; match to protein family HMM TIGR00241; 2-hydroxyglutaryl-CoA dehydratase subunit A 1827721 hgdC 7766400 hgdC Clostridium botulinum A2 str. Kyoto 2-hydroxyglutaryl-CoA dehydratase subunit A YP_002803975.1 1826960 D 536232 CDS YP_002803976.1 226948885 7766332 1827739..1828170 1 NC_012563.1 identified by match to protein family HMM PF01242; match to protein family HMM TIGR03367; queuosine biosynthesis protein QueD 1828170 queD 7766332 queD Clostridium botulinum A2 str. Kyoto queuosine biosynthesis protein QueD YP_002803976.1 1827739 D 536232 CDS YP_002803977.1 226948886 7765460 1828172..1828837 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 1828837 7765460 CLM_1796 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002803977.1 1828172 D 536232 CDS YP_002803978.1 226948887 7764585 1828841..1829431 1 NC_012563.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1829431 folE 7764585 folE Clostridium botulinum A2 str. Kyoto GTP cyclohydrolase I YP_002803978.1 1828841 D 536232 CDS YP_002803979.1 226948888 7767772 1829615..1830274 1 NC_012563.1 identified by match to protein family HMM PF06508; match to protein family HMM TIGR00364; ExsB protein 1830274 7767772 CLM_1798 Clostridium botulinum A2 str. Kyoto ExsB protein YP_002803979.1 1829615 D 536232 CDS YP_002803980.1 226948889 7766668 1830568..1831386 1 NC_012563.1 identified by match to protein family HMM PF02517; caax amino protease family protein 1831386 7766668 CLM_1799 Clostridium botulinum A2 str. Kyoto caax amino protease family protein YP_002803980.1 1830568 D 536232 CDS YP_002803981.1 226948890 7765576 1831533..1832489 1 NC_012563.1 identified by match to protein family HMM PF00015; methyl-accepting chemotaxis protein 1832489 7765576 CLM_1800 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002803981.1 1831533 D 536232 CDS YP_002803982.1 226948891 7766855 1832901..1833416 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF06161; hypothetical protein 1833416 7766855 CLM_1801 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803982.1 1832901 D 536232 CDS YP_002803983.1 226948892 7765812 1833738..1834157 1 NC_012563.1 hypothetical protein 1834157 7765812 CLM_1802 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803983.1 1833738 D 536232 CDS YP_002803984.1 226948893 7767169 1834179..1835117 1 NC_012563.1 identified by match to protein family HMM PF04198; putative deoxyribonucleoside regulator 1835117 7767169 CLM_1803 Clostridium botulinum A2 str. Kyoto putative deoxyribonucleoside regulator YP_002803984.1 1834179 D 536232 CDS YP_002803985.1 226948894 7766283 1835409..1836047 1 NC_012563.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1836047 deoC 7766283 deoC Clostridium botulinum A2 str. Kyoto deoxyribose-phosphate aldolase YP_002803985.1 1835409 D 536232 CDS YP_002803986.1 226948895 7764889 1836176..1837087 1 NC_012563.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR02152; ribokinase 1837087 rbsK 7764889 rbsK Clostridium botulinum A2 str. Kyoto ribokinase YP_002803986.1 1836176 D 536232 CDS YP_002803987.1 226948896 7767509 1837543..1838811 1 NC_012563.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase regulatory subunit 1838811 hisZ 7767509 hisZ Clostridium botulinum A2 str. Kyoto ATP phosphoribosyltransferase regulatory subunit YP_002803987.1 1837543 D 536232 CDS YP_002803988.1 226948897 7767037 1838836..1839474 1 NC_012563.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase catalytic subunit 1839474 hisG 7767037 hisG Clostridium botulinum A2 str. Kyoto ATP phosphoribosyltransferase catalytic subunit YP_002803988.1 1838836 D 536232 CDS YP_002803989.1 226948898 7765716 1839552..1840856 1 NC_012563.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1840856 hisD 7765716 hisD Clostridium botulinum A2 str. Kyoto histidinol dehydrogenase YP_002803989.1 1839552 D 536232 CDS YP_002803990.1 226948899 7764434 1841006..1841596 1 NC_012563.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 1841596 hisB 7764434 hisB Clostridium botulinum A2 str. Kyoto imidazoleglycerol-phosphate dehydratase YP_002803990.1 1841006 D 536232 CDS YP_002803991.1 226948900 7765154 1841724..1842329 1 NC_012563.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1842329 hisH 7765154 hisH Clostridium botulinum A2 str. Kyoto imidazole glycerol phosphate synthase subunit HisH YP_002803991.1 1841724 D 536232 CDS YP_002803992.1 226948901 7767720 1842326..1843054 1 NC_012563.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1843054 hisA 7767720 hisA Clostridium botulinum A2 str. Kyoto 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_002803992.1 1842326 D 536232 CDS YP_002803993.1 226948902 7767615 1843051..1844115 1 NC_012563.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1844115 hisC 7767615 hisC Clostridium botulinum A2 str. Kyoto histidinol-phosphate aminotransferase YP_002803993.1 1843051 D 536232 CDS YP_002803994.1 226948903 7766576 1844312..1845073 1 NC_012563.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1845073 hisF 7766576 hisF Clostridium botulinum A2 str. Kyoto imidazole glycerol phosphate synthase subunit HisF YP_002803994.1 1844312 D 536232 CDS YP_002803995.1 226948904 7764879 1845227..1845559 1 NC_012563.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 1845559 hisI 7764879 hisI Clostridium botulinum A2 str. Kyoto phosphoribosyl-AMP cyclohydrolase YP_002803995.1 1845227 D 536232 CDS YP_002803996.1 226948905 7767312 1845687..1846019 1 NC_012563.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 1846019 hisE 7767312 hisE Clostridium botulinum A2 str. Kyoto phosphoribosyl-ATP pyrophosphatase YP_002803996.1 1845687 D 536232 CDS YP_002803997.1 226948906 7765941 1846155..1846850 1 NC_012563.1 identified by match to protein family HMM PF04143; hypothetical protein 1846850 7765941 CLM_1816 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803997.1 1846155 D 536232 CDS YP_002803998.1 226948907 7765627 1846864..1847085 1 NC_012563.1 identified by match to protein family HMM PF01206; hypothetical protein 1847085 7765627 CLM_1817 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803998.1 1846864 D 536232 CDS YP_002803999.1 226948908 7764277 1847103..1847630 1 NC_012563.1 identified by match to protein family HMM PF04143; hypothetical protein 1847630 7764277 CLM_1818 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002803999.1 1847103 D 536232 CDS YP_002804000.1 226948909 7767859 complement(1847661..1848551) 1 NC_012563.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1848551 7767859 CLM_1819 Clostridium botulinum A2 str. Kyoto LysR family transcriptional regulator YP_002804000.1 1847661 R 536232 CDS YP_002804001.1 226948910 7766500 1848816..1850066 1 NC_012563.1 identified by match to protein family HMM PF01235; sodium:alanine symporter family protein 1850066 7766500 CLM_1820 Clostridium botulinum A2 str. Kyoto sodium:alanine symporter family protein YP_002804001.1 1848816 D 536232 CDS YP_002804002.1 226948911 7767272 1850147..1851847 1 NC_012563.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00581; match to protein family HMM PF02852; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase family protein 1851847 7767272 CLM_1821 Clostridium botulinum A2 str. Kyoto pyridine nucleotide-disulfide oxidoreductase family protein YP_002804002.1 1850147 D 536232 CDS YP_002804003.1 226948912 7765253 1852000..1853256 1 NC_012563.1 identified by match to protein family HMM PF04143; hypothetical protein 1853256 7765253 CLM_1822 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804003.1 1852000 D 536232 CDS YP_002804004.1 226948913 7764416 1853491..1854198 1 NC_012563.1 identified by similarity to GB:AAF99691.1; match to protein family HMM PF00005; antibiotic ABC transporter ATP-binding protein 1854198 7764416 CLM_1823 Clostridium botulinum A2 str. Kyoto antibiotic ABC transporter ATP-binding protein YP_002804004.1 1853491 D 536232 CDS YP_002804005.1 226948914 7767482 1854201..1854932 1 NC_012563.1 putative lantibiotic ABC transporter permease 1854932 7767482 CLM_1824 Clostridium botulinum A2 str. Kyoto putative lantibiotic ABC transporter permease YP_002804005.1 1854201 D 536232 CDS YP_002804006.1 226948915 7766599 1854935..1855678 1 NC_012563.1 putative lantibiotic ABC transporter permease 1855678 7766599 CLM_1825 Clostridium botulinum A2 str. Kyoto putative lantibiotic ABC transporter permease YP_002804006.1 1854935 D 536232 CDS YP_002804007.1 226948916 7766801 1855795..1856454 1 NC_012563.1 identified by similarity to SP:P33112; match to protein family HMM PF00072; match to protein family HMM PF00486; putative lantibiotic biosynthesis regulatory protein 1856454 7766801 CLM_1826 Clostridium botulinum A2 str. Kyoto putative lantibiotic biosynthesis regulatory protein YP_002804007.1 1855795 D 536232 CDS YP_002804008.1 226948917 7767404 1856445..1857824 1 NC_012563.1 identified by similarity to SP:P33113; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; putative lantibiotic biosynthesis sensor histidine kinase 1857824 7767404 CLM_1827 Clostridium botulinum A2 str. Kyoto putative lantibiotic biosynthesis sensor histidine kinase YP_002804008.1 1856445 D 536232 CDS YP_002804009.1 226948918 7764573 1858388..1859614 1 NC_012563.1 identified by match to protein family HMM PF02274; match to protein family HMM TIGR01078; arginine deiminase 1859614 arcA 7764573 arcA Clostridium botulinum A2 str. Kyoto arginine deiminase YP_002804009.1 1858388 D 536232 CDS YP_002804010.1 226948919 7765201 1859717..1861135 1 NC_012563.1 identified by match to protein family HMM PF00324; arginine/ornithine antiporter 1861135 arcD 7765201 arcD Clostridium botulinum A2 str. Kyoto arginine/ornithine antiporter YP_002804010.1 1859717 D 536232 CDS YP_002804011.1 226948920 7765372 complement(1861354..1862004) 1 NC_012563.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; putative hemolysin III 1862004 7765372 CLM_1830 Clostridium botulinum A2 str. Kyoto putative hemolysin III YP_002804011.1 1861354 R 536232 CDS YP_002804012.1 226948921 7765946 1862375..1862971 1 NC_012563.1 identified by match to protein family HMM PF08876; hypothetical protein 1862971 7765946 CLM_1831 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804012.1 1862375 D 536232 CDS YP_002804013.1 226948922 7765800 1863107..1863247 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1863247 7765800 CLM_1832 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804013.1 1863107 D 536232 CDS YP_002804014.1 226948923 7764862 1863340..1863900 1 NC_012563.1 identified by match to protein family HMM PF01966; HD domain-containing protein 1863900 7764862 CLM_1833 Clostridium botulinum A2 str. Kyoto HD domain-containing protein YP_002804014.1 1863340 D 536232 CDS YP_002804015.1 226948924 7768153 complement(1866813..1867151) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1867151 7768153 CLM_1837 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804015.1 1866813 R 536232 CDS YP_002804016.1 226948925 7764475 1867418..1870711 1 NC_012563.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF04851; match to protein family HMM PF08455; helicase, Snf2 family 1870711 7764475 CLM_1838 Clostridium botulinum A2 str. Kyoto helicase, Snf2 family YP_002804016.1 1867418 D 536232 CDS YP_002804017.1 226948926 7768019 1870903..1871724 1 NC_012563.1 identified by match to protein family HMM PF04607; RelA/SpoT domain-containing protein 1871724 7768019 CLM_1839 Clostridium botulinum A2 str. Kyoto RelA/SpoT domain-containing protein YP_002804017.1 1870903 D 536232 CDS YP_002804018.1 226948927 7766158 1871942..1872397 1 NC_012563.1 hypothetical protein 1872397 7766158 CLM_1840 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804018.1 1871942 D 536232 CDS YP_002804019.1 226948928 7766920 1872778..1873767 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 1873767 7766920 CLM_1841 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002804019.1 1872778 D 536232 CDS YP_002804020.1 226948929 7767846 1873916..1875670 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 1875670 7767846 CLM_1842 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein/permease YP_002804020.1 1873916 D 536232 CDS YP_002804021.1 226948930 7767161 1875672..1877396 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF02463; ABC transporter ATP-binding protein/permease 1877396 7767161 CLM_1843 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein/permease YP_002804021.1 1875672 D 536232 CDS YP_002804022.1 226948931 7766036 1877788..1878789 1 NC_012563.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcriptional regulator 1878789 7766036 CLM_1844 Clostridium botulinum A2 str. Kyoto LacI family transcriptional regulator YP_002804022.1 1877788 D 536232 CDS YP_002804023.1 226948932 7765474 1879091..1880038 1 NC_012563.1 identified by similarity to SP:P54495; match to protein family HMM PF00480; putative glucokinase 1880038 7765474 CLM_1845 Clostridium botulinum A2 str. Kyoto putative glucokinase YP_002804023.1 1879091 D 536232 CDS YP_002804024.1 226948933 7764618 1880285..1881949 1 NC_012563.1 identified by match to protein family HMM PF00128; glycosyl hydrolase, family 13 1881949 7764618 CLM_1846 Clostridium botulinum A2 str. Kyoto glycosyl hydrolase, family 13 YP_002804024.1 1880285 D 536232 CDS YP_002804025.1 226948934 7767791 1881991..1883649 1 NC_012563.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR02003; PTS system glucose/glucoside family transporter subunit IIBC 1883649 7767791 CLM_1847 Clostridium botulinum A2 str. Kyoto PTS system glucose/glucoside family transporter subunit IIBC YP_002804025.1 1881991 D 536232 CDS YP_002804026.1 226948935 7766905 1883653..1884444 1 NC_012563.1 identified by match to protein family HMM PF03372; endonuclease/exonuclease/phosphatase family protein 1884444 7766905 CLM_1848 Clostridium botulinum A2 str. Kyoto endonuclease/exonuclease/phosphatase family protein YP_002804026.1 1883653 D 536232 CDS YP_002804027.1 226948936 7766337 1884669..1885292 1 NC_012563.1 identified by match to protein family HMM TIGR02840; putative sporulation protein YtaF 1885292 7766337 CLM_1849 Clostridium botulinum A2 str. Kyoto putative sporulation protein YtaF YP_002804027.1 1884669 D 536232 CDS YP_002804028.1 226948937 7764934 complement(1885581..1885916) 1 NC_012563.1 hypothetical protein 1885916 7764934 CLM_1850 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804028.1 1885581 R 536232 CDS YP_002804029.1 226948938 7764658 1886244..1887809 1 NC_012563.1 hypothetical protein 1887809 7764658 CLM_1851 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804029.1 1886244 D 536232 CDS YP_002804030.1 226948939 7764319 1887967..1888422 1 NC_012563.1 hypothetical protein 1888422 7764319 CLM_1852 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804030.1 1887967 D 536232 CDS YP_002804031.1 226948940 7767366 complement(1888718..1890820) 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 1890820 7767366 CLM_1853 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002804031.1 1888718 R 536232 CDS YP_002804032.1 226948941 7767012 complement(1890858..1891550) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 1891550 7767012 CLM_1854 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002804032.1 1890858 R 536232 CDS YP_002804033.1 226948942 7766146 1892144..1893370 1 NC_012563.1 identified by match to protein family HMM PF07690; major facilitator family transporter 1893370 7766146 CLM_1855 Clostridium botulinum A2 str. Kyoto major facilitator family transporter YP_002804033.1 1892144 D 536232 CDS YP_002804034.1 226948943 7764779 complement(1893448..1893654) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 1893654 7764779 CLM_1856 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804034.1 1893448 R 536232 CDS YP_002804035.1 226948944 7766393 complement(1893924..1894784) 1 NC_012563.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD superfamily hydrolase 1894784 7766393 CLM_1857 Clostridium botulinum A2 str. Kyoto HAD superfamily hydrolase YP_002804035.1 1893924 R 536232 CDS YP_002804036.1 226948945 7765027 complement(1894793..1895560) 1 NC_012563.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator 1895560 7765027 CLM_1858 Clostridium botulinum A2 str. Kyoto DeoR family transcriptional regulator YP_002804036.1 1894793 R 536232 CDS YP_002804037.1 226948946 7764231 1896074..1896613 1 NC_012563.1 identified by match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; sigma-70 family RNA polymerase sigma factor 1896613 7764231 CLM_1859 Clostridium botulinum A2 str. Kyoto sigma-70 family RNA polymerase sigma factor YP_002804037.1 1896074 D 536232 CDS YP_002804038.1 226948947 7767276 1896803..1896982 1 NC_012563.1 hypothetical protein 1896982 7767276 CLM_1860 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804038.1 1896803 D 536232 CDS YP_002804039.1 226948948 7766854 complement(1897165..1900794) 1 NC_012563.1 identified by similarity to GB:BAA77453.1; match to protein family HMM PF00801; match to protein family HMM PF01752; match to protein family HMM PF04151; match to protein family HMM PF08453; collagenase 1900794 colG 7766854 colG Clostridium botulinum A2 str. Kyoto collagenase YP_002804039.1 1897165 R 536232 CDS YP_002804040.1 226948949 7765386 1901268..1902155 1 NC_012563.1 identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; methylenetetrahydrofolate reductase 1902155 metF 7765386 metF Clostridium botulinum A2 str. Kyoto methylenetetrahydrofolate reductase YP_002804040.1 1901268 D 536232 CDS YP_002804041.1 226948950 7767052 1902310..1902990 1 NC_012563.1 identified by match to protein family HMM PF02965; hypothetical protein 1902990 7767052 CLM_1864 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804041.1 1902310 D 536232 CDS YP_002804042.1 226948951 7767974 1902980..1905358 1 NC_012563.1 identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607; 5-methyltetrahydrofolate:homocysteine S-methyltransferase 1905358 7767974 CLM_1865 Clostridium botulinum A2 str. Kyoto 5-methyltetrahydrofolate:homocysteine S-methyltransferase YP_002804042.1 1902980 D 536232 CDS YP_002804043.1 226948952 7764899 complement(1905646..1906062) 1 NC_012563.1 hypothetical protein 1906062 7764899 CLM_1866 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804043.1 1905646 R 536232 CDS YP_002804044.1 226948953 7765797 1906568..1907140 1 NC_012563.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 1907140 7765797 CLM_1867 Clostridium botulinum A2 str. Kyoto RNA polymerase factor sigma-70 YP_002804044.1 1906568 D 536232 CDS YP_002804045.1 226948954 7764886 1907133..1908581 1 NC_012563.1 hypothetical protein 1908581 7764886 CLM_1868 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804045.1 1907133 D 536232 CDS YP_002804046.1 226948955 7767998 1908931..1910883 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; aco operon transcriptional regulator 1910883 acoR 7767998 acoR Clostridium botulinum A2 str. Kyoto aco operon transcriptional regulator YP_002804046.1 1908931 D 536232 CDS YP_002804047.1 226948956 7765110 1911052..1911423 1 NC_012563.1 identified by match to protein family HMM PF09585; match to protein family HMM TIGR02058; hypothetical protein 1911423 7765110 CLM_1870 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804047.1 1911052 D 536232 CDS YP_002804048.1 226948957 7765275 1911444..1912427 1 NC_012563.1 identified by match to protein family HMM PF00676; TPP-dependent acetoin dehydrogenase complex, E1 component subunit alpha 1912427 acoA 7765275 acoA Clostridium botulinum A2 str. Kyoto TPP-dependent acetoin dehydrogenase complex, E1 component subunit alpha YP_002804048.1 1911444 D 536232 CDS YP_002804049.1 226948958 7766381 1912430..1913401 1 NC_012563.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; TPP-dependent acetoin dehydrogenase complex, E1 component subunit beta 1913401 acoB 7766381 acoB Clostridium botulinum A2 str. Kyoto TPP-dependent acetoin dehydrogenase complex, E1 component subunit beta YP_002804049.1 1912430 D 536232 CDS YP_002804050.1 226948959 7767023 1913454..1914449 1 NC_012563.1 identified by similarity to SP:P27748; match to protein family HMM PF01513; putative acetoin catabolism protein X 1914449 7767023 CLM_1873 Clostridium botulinum A2 str. Kyoto putative acetoin catabolism protein X YP_002804050.1 1913454 D 536232 CDS YP_002804051.1 226948960 7766165 1914485..1915795 1 NC_012563.1 identified by similarity to GB:AAA21747.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; TPP-dependent acetoin dehydrogenase complex, E2 component, dihydrolipoyllysine-residue acetyltransferase 1915795 acoC 7766165 acoC Clostridium botulinum A2 str. Kyoto TPP-dependent acetoin dehydrogenase complex, E2 component, dihydrolipoyllysine-residue acetyltransferase YP_002804051.1 1914485 D 536232 CDS YP_002804052.1 226948961 7767311 1915808..1917199 1 NC_012563.1 identified by similarity to GB:AAA21748.1; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350; TPP-dependent acetoin dehydrogenase complex, E3 component, dihydrolipoyl dehydrogenase 1917199 acoL 7767311 acoL Clostridium botulinum A2 str. Kyoto TPP-dependent acetoin dehydrogenase complex, E3 component, dihydrolipoyl dehydrogenase YP_002804052.1 1915808 D 536232 CDS YP_002804053.1 226948962 7765836 1917224..1918219 1 NC_012563.1 identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545; putative lipoate-protein ligase A 1918219 7765836 CLM_1876 Clostridium botulinum A2 str. Kyoto putative lipoate-protein ligase A YP_002804053.1 1917224 D 536232 CDS YP_002804054.1 226948963 7765519 1918608..1919753 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00571; match to protein family HMM TIGR01186; glycine/betaine/L-proline ABC transporter ATP-binding protein 1919753 7765519 CLM_1877 Clostridium botulinum A2 str. Kyoto glycine/betaine/L-proline ABC transporter ATP-binding protein YP_002804054.1 1918608 D 536232 CDS YP_002804055.1 226948964 7764877 1919746..1921329 1 NC_012563.1 identified by match to protein family HMM PF00528; match to protein family HMM PF04069; glycine betaine/L-proline ABC transporter permease/glycine betaine/L-proline-binding protein 1921329 7764877 CLM_1878 Clostridium botulinum A2 str. Kyoto glycine betaine/L-proline ABC transporter permease/glycine betaine/L-proline-binding protein YP_002804055.1 1919746 D 536232 CDS YP_002804056.1 226948965 7765731 1921623..1923104 1 NC_012563.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1923104 thrC 7765731 thrC Clostridium botulinum A2 str. Kyoto threonine synthase YP_002804056.1 1921623 D 536232 CDS YP_002804057.1 226948966 7766933 1923114..1924007 1 NC_012563.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1924007 thrB 7766933 thrB Clostridium botulinum A2 str. Kyoto homoserine kinase YP_002804057.1 1923114 D 536232 CDS YP_002804058.1 226948967 7767530 1924134..1925453 1 NC_012563.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 1925453 7767530 CLM_1881 Clostridium botulinum A2 str. Kyoto aspartate kinase YP_002804058.1 1924134 D 536232 CDS YP_002804059.1 226948968 7767595 1925675..1926952 1 NC_012563.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1926952 hom 7767595 hom Clostridium botulinum A2 str. Kyoto homoserine dehydrogenase YP_002804059.1 1925675 D 536232 CDS YP_002804060.1 226948969 7764293 1927638..1929548 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728; match to protein family HMM TIGR00229; sensory box sigma-54 dependent transcriptional regulator 1929548 7764293 CLM_1883 Clostridium botulinum A2 str. Kyoto sensory box sigma-54 dependent transcriptional regulator YP_002804060.1 1927638 D 536232 CDS YP_002804061.1 226948970 7764707 1930057..1931223 1 NC_012563.1 identified by similarity to SP:P13604; match to protein family HMM PF00465; NADH-dependent butanol dehydrogenase 1931223 7764707 CLM_1884 Clostridium botulinum A2 str. Kyoto NADH-dependent butanol dehydrogenase YP_002804061.1 1930057 D 536232 CDS YP_002804062.1 226948971 7766020 1931552..1932439 1 NC_012563.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00970; ferredoxin-NADP(+) reductase subunit alpha 1932439 7766020 CLM_1885 Clostridium botulinum A2 str. Kyoto ferredoxin-NADP(+) reductase subunit alpha YP_002804062.1 1931552 D 536232 CDS YP_002804063.1 226948972 7766469 1932439..1933821 1 NC_012563.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 1933821 gltA 7766469 gltA Clostridium botulinum A2 str. Kyoto putative oxidoreductase YP_002804063.1 1932439 D 536232 CDS YP_002804064.1 226948973 7767747 1934050..1936014 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728; sensory box sigma-54 dependent transcriptional regulator 1936014 7767747 CLM_1887 Clostridium botulinum A2 str. Kyoto sensory box sigma-54 dependent transcriptional regulator YP_002804064.1 1934050 D 536232 CDS YP_002804065.1 226948974 7766451 1936021..1936722 1 NC_012563.1 identified by match to protein family HMM PF00805; pentapeptide repeat family protein 1936722 7766451 CLM_1888 Clostridium botulinum A2 str. Kyoto pentapeptide repeat family protein YP_002804065.1 1936021 D 536232 CDS YP_002804066.1 226948975 7767546 1937145..1938224 1 NC_012563.1 identified by match to protein family HMM PF02368; Ig group 2 domain-containing protein 1938224 7767546 CLM_1889 Clostridium botulinum A2 str. Kyoto Ig group 2 domain-containing protein YP_002804066.1 1937145 D 536232 CDS YP_002804067.1 226948976 7764238 1938333..1938536 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1938536 7764238 CLM_1890 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804067.1 1938333 D 536232 CDS YP_002804068.1 226948977 7765286 1938716..1938937 1 NC_012563.1 putative lipoprotein 1938937 7765286 CLM_1891 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002804068.1 1938716 D 536232 CDS YP_002804069.1 226948978 7765786 1939296..1939457 1 NC_012563.1 hypothetical protein 1939457 7765786 CLM_1892 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804069.1 1939296 D 536232 CDS YP_002804070.1 226948979 7767794 1939745..1940119 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF08239; hypothetical protein 1940119 7767794 CLM_1893 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804070.1 1939745 D 536232 CDS YP_002804071.1 226948980 7764287 1940305..1940529 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1940529 7764287 CLM_1894 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804071.1 1940305 D 536232 CDS YP_002804072.1 226948981 7764919 1940997..1941233 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1941233 7764919 CLM_1895 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804072.1 1940997 D 536232 CDS YP_002804073.1 226948982 7766499 1941389..1941940 1 NC_012563.1 hypothetical protein 1941940 7766499 CLM_1896 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804073.1 1941389 D 536232 CDS YP_002804074.1 226948983 7767645 1941978..1942265 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; hypothetical protein 1942265 7767645 CLM_1897 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804074.1 1941978 D 536232 CDS YP_002804075.1 226948984 7765227 1942766..1943398 1 NC_012563.1 hypothetical protein 1943398 7765227 CLM_1898 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804075.1 1942766 D 536232 CDS YP_002804076.1 226948985 7766640 1943431..1943985 1 NC_012563.1 identified by match to protein family HMM PF01814; hypothetical protein 1943985 7766640 CLM_1899 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804076.1 1943431 D 536232 CDS YP_002804077.1 226948986 7767958 1944423..1945592 1 NC_012563.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1945592 alr 7767958 alr Clostridium botulinum A2 str. Kyoto alanine racemase YP_002804077.1 1944423 D 536232 CDS YP_002804078.1 226948987 7764400 1946051..1947523 1 NC_012563.1 identified by match to protein family HMM PF00015; methyl-accepting chemotaxis protein 1947523 7764400 CLM_1901 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002804078.1 1946051 D 536232 CDS YP_002804079.1 226948988 7765162 1947611..1948951 1 NC_012563.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; xanthine/uracil permease family protein 1948951 7765162 CLM_1902 Clostridium botulinum A2 str. Kyoto xanthine/uracil permease family protein YP_002804079.1 1947611 D 536232 CDS YP_002804080.1 226948989 7767909 1949191..1950024 1 NC_012563.1 identified by match to protein family HMM PF06161; hypothetical protein 1950024 7767909 CLM_1903 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804080.1 1949191 D 536232 CDS YP_002804081.1 226948990 7767959 complement(1950241..1951125) 1 NC_012563.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 1951125 7767959 CLM_1904 Clostridium botulinum A2 str. Kyoto short chain dehydrogenase/reductase family oxidoreductase YP_002804081.1 1950241 R 536232 CDS YP_002804082.1 226948991 7765701 1951601..1953607 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 1953607 7765701 CLM_1905 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002804082.1 1951601 D 536232 CDS YP_002804083.1 226948992 7764603 1954520..1955533 1 NC_012563.1 identified by match to protein family HMM PF07656; KWG repeat-containing protein 1955533 7764603 CLM_1906 Clostridium botulinum A2 str. Kyoto KWG repeat-containing protein YP_002804083.1 1954520 D 536232 CDS YP_002804084.1 226948993 7767422 complement(1955686..1956237) 1 NC_012563.1 hypothetical protein 1956237 7767422 CLM_1907 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804084.1 1955686 R 536232 CDS YP_002804085.1 226948994 7767876 1956597..1959830 1 NC_012563.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455; helicase, SNF2/RAD54 family 1959830 7767876 CLM_1908 Clostridium botulinum A2 str. Kyoto helicase, SNF2/RAD54 family YP_002804085.1 1956597 D 536232 CDS YP_002804086.1 226948995 7764512 complement(1959886..1960167) 1 NC_012563.1 identified by match to protein family HMM PF01980; hypothetical protein 1960167 7764512 CLM_1909 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804086.1 1959886 R 536232 CDS YP_002804087.1 226948996 7765612 1960410..1960538 1 NC_012563.1 hypothetical protein 1960538 7765612 CLM_1910 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804087.1 1960410 D 536232 CDS YP_002804088.1 226948997 7766210 1960768..1961292 1 NC_012563.1 identified by match to protein family HMM PF02663; formylmethanofuran dehydrogenase E subunit-like protein 1961292 7766210 CLM_1911 Clostridium botulinum A2 str. Kyoto formylmethanofuran dehydrogenase E subunit-like protein YP_002804088.1 1960768 D 536232 CDS YP_002804089.1 226948998 7766170 1961429..1963024 1 NC_012563.1 identified by match to protein family HMM PF00496; peptide ABC transporter substrate-binding protein 1963024 7766170 CLM_1912 Clostridium botulinum A2 str. Kyoto peptide ABC transporter substrate-binding protein YP_002804089.1 1961429 D 536232 CDS YP_002804090.1 226948999 7766490 1963038..1964012 1 NC_012563.1 identified by match to protein family HMM PF00528; peptide ABC transporter permease 1964012 7766490 CLM_1913 Clostridium botulinum A2 str. Kyoto peptide ABC transporter permease YP_002804090.1 1963038 D 536232 CDS YP_002804091.1 226949000 7766749 1964016..1964837 1 NC_012563.1 identified by match to protein family HMM PF00528; peptide ABC transporter permease 1964837 7766749 CLM_1914 Clostridium botulinum A2 str. Kyoto peptide ABC transporter permease YP_002804091.1 1964016 D 536232 CDS YP_002804092.1 226949001 7766075 1964868..1966550 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; ABC transporter ATP-binding protein 1966550 7766075 CLM_1915 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002804092.1 1964868 D 536232 CDS YP_002804093.1 226949002 7764782 complement(1966793..1967380) 1 NC_012563.1 identified by match to protein family HMM PF00929; putative DNA polymerase III subunit epsilon 1967380 7764782 CLM_1916 Clostridium botulinum A2 str. Kyoto putative DNA polymerase III subunit epsilon YP_002804093.1 1966793 R 536232 CDS YP_002804094.1 226949003 7767402 1967675..1968625 1 NC_012563.1 identified by match to protein family HMM PF06207; hypothetical protein 1968625 7767402 CLM_1917 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804094.1 1967675 D 536232 CDS YP_002804095.1 226949004 7764481 1968896..1969531 1 NC_012563.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242; UbiE/COQ5 family methyltransferase 1969531 7764481 CLM_1918 Clostridium botulinum A2 str. Kyoto UbiE/COQ5 family methyltransferase YP_002804095.1 1968896 D 536232 CDS YP_002804096.1 226949005 7764852 complement(1969680..1970120) 1 NC_012563.1 identified by match to protein family HMM PF00011; heat shock protein 1970120 7764852 CLM_1919 Clostridium botulinum A2 str. Kyoto heat shock protein YP_002804096.1 1969680 R 536232 CDS YP_002804097.1 226949006 7767733 1970471..1971655 1 NC_012563.1 identified by match to protein family HMM PF07690; major facilitator family protein 1971655 7767733 CLM_1920 Clostridium botulinum A2 str. Kyoto major facilitator family protein YP_002804097.1 1970471 D 536232 CDS YP_002804098.1 226949007 7767130 1971806..1972369 1 NC_012563.1 identified by match to protein family HMM PF00440; hypothetical protein 1972369 7767130 CLM_1921 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804098.1 1971806 D 536232 CDS YP_002804099.1 226949008 7766001 1972362..1972544 1 NC_012563.1 DeoR family transcriptional regulator 1972544 7766001 CLM_1922 Clostridium botulinum A2 str. Kyoto DeoR family transcriptional regulator YP_002804099.1 1972362 D 536232 CDS YP_002804100.1 226949009 7767247 1972570..1973475 1 NC_012563.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; 1-phosphofructokinase 1973475 pfkB 7767247 pfkB Clostridium botulinum A2 str. Kyoto 1-phosphofructokinase YP_002804100.1 1972570 D 536232 CDS YP_002804101.1 226949010 7764652 complement(1973592..1974971) 1 NC_012563.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter 1974971 7764652 CLM_1924 Clostridium botulinum A2 str. Kyoto amino acid/peptide transporter YP_002804101.1 1973592 R 536232 CDS YP_002804102.1 226949011 7767251 1975395..1975550 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1975550 7767251 CLM_1925 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804102.1 1975395 D 536232 CDS YP_002804103.1 226949012 7764647 1975702..1976676 1 NC_012563.1 hypothetical protein 1976676 7764647 CLM_1926 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804103.1 1975702 D 536232 CDS YP_002804104.1 226949013 7765514 complement(1976787..1977320) 1 NC_012563.1 hypothetical protein 1977320 7765514 CLM_1927 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804104.1 1976787 R 536232 CDS YP_002804105.1 226949014 7766880 1977583..1977738 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1977738 7766880 CLM_1928 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804105.1 1977583 D 536232 CDS YP_002804106.1 226949015 7767801 1977769..1978728 1 NC_012563.1 identified by match to protein family HMM PF00294; match to protein family HMM PF08543; PfkB family kinase 1978728 7767801 CLM_1929 Clostridium botulinum A2 str. Kyoto PfkB family kinase YP_002804106.1 1977769 D 536232 CDS YP_002804107.1 226949016 7765149 complement(1978872..1979507) 1 NC_012563.1 identified by match to protein family HMM PF00188; match to protein family HMM PF01476; match to protein family HMM TIGR02899; spore coat assembly protein SafA 1979507 safA 7765149 safA Clostridium botulinum A2 str. Kyoto spore coat assembly protein SafA YP_002804107.1 1978872 R 536232 CDS YP_002804108.1 226949017 7766274 complement(1979908..1980327) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1980327 7766274 CLM_1931 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804108.1 1979908 R 536232 CDS YP_002804109.1 226949018 7767160 1980736..1982739 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 1982739 7767160 CLM_1932 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002804109.1 1980736 D 536232 CDS YP_002804110.1 226949019 7765273 complement(1983002..1984582) 1 NC_012563.1 identified by match to protein family HMM PF00005; putative drug resistance ABC transporter ATP-binding protein 1984582 7765273 CLM_1933 Clostridium botulinum A2 str. Kyoto putative drug resistance ABC transporter ATP-binding protein YP_002804110.1 1983002 R 536232 CDS YP_002804111.1 226949020 7767911 1985048..1985902 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01077; match to protein family HMM PF03460; sulfite/nitrite reductase family protein 1985902 7767911 CLM_1934 Clostridium botulinum A2 str. Kyoto sulfite/nitrite reductase family protein YP_002804111.1 1985048 D 536232 CDS YP_002804112.1 226949021 7764524 complement(1986112..1987005) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF01584; chemotaxis protein CheV 1987005 cheV 7764524 cheV Clostridium botulinum A2 str. Kyoto chemotaxis protein CheV YP_002804112.1 1986112 R 536232 CDS YP_002804113.1 226949022 7766858 1987378..1988643 1 NC_012563.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD/DEAH box family ATP-dependent RNA helicase 1988643 7766858 CLM_1936 Clostridium botulinum A2 str. Kyoto DEAD/DEAH box family ATP-dependent RNA helicase YP_002804113.1 1987378 D 536232 CDS YP_002804114.1 226949023 7766232 1988966..1989802 1 NC_012563.1 identified by match to protein family HMM PF00575; RNA-binding protein 1989802 7766232 CLM_1937 Clostridium botulinum A2 str. Kyoto RNA-binding protein YP_002804114.1 1988966 D 536232 CDS YP_002804115.1 226949024 7765659 1989982..1991427 1 NC_012563.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; ATP-dependent RNA helicase DeaD 1991427 deaD 7765659 deaD Clostridium botulinum A2 str. Kyoto ATP-dependent RNA helicase DeaD YP_002804115.1 1989982 D 536232 CDS YP_002804116.1 226949025 7767303 1991592..1996040 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 1996040 7767303 CLM_1939 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804116.1 1991592 D 536232 CDS YP_002804117.1 226949026 7766261 1996435..2000502 1 NC_012563.1 identified by match to protein family HMM PF00560; match to protein family HMM PF07532; leucine rich repeat-containing protein 2000502 7766261 CLM_1940 Clostridium botulinum A2 str. Kyoto leucine rich repeat-containing protein YP_002804117.1 1996435 D 536232 CDS YP_002804118.1 226949027 7766071 2000906..2001835 1 NC_012563.1 identified by match to protein family HMM PF01832; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase domain-containing protein 2001835 7766071 CLM_1941 Clostridium botulinum A2 str. Kyoto mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase domain-containing protein YP_002804118.1 2000906 D 536232 CDS YP_002804119.1 226949028 7765030 complement(2001961..2002476) 1 NC_012563.1 identified by match to protein family HMM PF00210; ferritin family protein 2002476 7765030 CLM_1942 Clostridium botulinum A2 str. Kyoto ferritin family protein YP_002804119.1 2001961 R 536232 CDS YP_002804120.1 226949029 7767470 2002929..2003783 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00072; match to protein family HMM PF04509; chemotaxis response regulator/CheC-like domain-containing protein 2003783 7767470 CLM_1943 Clostridium botulinum A2 str. Kyoto chemotaxis response regulator/CheC-like domain-containing protein YP_002804120.1 2002929 D 536232 CDS YP_002804121.1 226949030 7766553 2003783..2004244 1 NC_012563.1 identified by match to protein family HMM PF04509; chemotaxis protein CheX 2004244 cheX 7766553 cheX Clostridium botulinum A2 str. Kyoto chemotaxis protein CheX YP_002804121.1 2003783 D 536232 CDS YP_002804122.1 226949031 7767410 complement(2004417..2005775) 1 NC_012563.1 identified by match to protein family HMM PF07670; hypothetical protein 2005775 7767410 CLM_1945 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804122.1 2004417 R 536232 CDS YP_002804123.1 226949032 7766517 2006514..2006717 1 NC_012563.1 identified by match to protein family HMM PF00269; small, acid-soluble spore protein alpha 2006717 7766517 CLM_1946 Clostridium botulinum A2 str. Kyoto small, acid-soluble spore protein alpha YP_002804123.1 2006514 D 536232 CDS YP_002804124.1 226949033 7765188 2006779..2006979 1 NC_012563.1 identified by match to protein family HMM PF00269; small, acid-soluble spore protein beta 2006979 7765188 CLM_1947 Clostridium botulinum A2 str. Kyoto small, acid-soluble spore protein beta YP_002804124.1 2006779 D 536232 CDS YP_002804125.1 226949034 7767074 2008418..2009398 1 NC_012563.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 2009398 xerC 7767074 xerC Clostridium botulinum A2 str. Kyoto site-specific tyrosine recombinase XerC YP_002804125.1 2008418 D 536232 CDS YP_002804126.1 226949035 7767129 complement(2009714..2010187) 1 NC_012563.1 hypothetical protein 2010187 7767129 CLM_1951 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804126.1 2009714 R 536232 CDS YP_002804127.1 226949036 7765763 2010486..2011091 1 NC_012563.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 2011091 lexA 7765763 lexA Clostridium botulinum A2 str. Kyoto LexA repressor YP_002804127.1 2010486 D 536232 CDS YP_002804128.1 226949037 7764697 complement(2011288..2012571) 1 NC_012563.1 identified by match to protein family HMM PF01053; match to protein family HMM PF06838; aluminum resistance protein 2012571 7764697 CLM_1953 Clostridium botulinum A2 str. Kyoto aluminum resistance protein YP_002804128.1 2011288 R 536232 CDS YP_002804129.1 226949038 7765947 complement(2012672..2012929) 1 NC_012563.1 identified by match to protein family HMM PF01423; match to protein family HMM TIGR02383; RNA chaperone Hfq 2012929 hfq 7765947 hfq Clostridium botulinum A2 str. Kyoto RNA chaperone Hfq YP_002804129.1 2012672 R 536232 CDS YP_002804130.1 226949039 7764776 complement(2013015..2013950) 1 NC_012563.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 2013950 miaA 7764776 miaA Clostridium botulinum A2 str. Kyoto tRNA delta(2)-isopentenylpyrophosphate transferase YP_002804130.1 2013015 R 536232 CDS YP_002804131.1 226949040 7765390 complement(2013965..2015965) 1 NC_012563.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 2015965 mutL 7765390 mutL Clostridium botulinum A2 str. Kyoto DNA mismatch repair protein YP_002804131.1 2013965 R 536232 CDS YP_002804132.1 226949041 7764210 complement(2016099..2018897) 1 NC_012563.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2018897 mutS 7764210 mutS Clostridium botulinum A2 str. Kyoto DNA mismatch repair protein MutS YP_002804132.1 2016099 R 536232 CDS YP_002804133.1 226949042 7767605 complement(2018977..2020329) 1 NC_012563.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 2020329 miaB 7767605 miaB Clostridium botulinum A2 str. Kyoto (dimethylallyl)adenosine tRNA methylthiotransferase YP_002804133.1 2018977 R 536232 CDS YP_002804134.1 226949043 7766523 2020801..2021991 1 NC_012563.1 identified by match to protein family HMM PF00155; class I/II aminotransferase 2021991 7766523 CLM_1959 Clostridium botulinum A2 str. Kyoto class I/II aminotransferase YP_002804134.1 2020801 D 536232 CDS YP_002804135.1 226949044 7764811 2022076..2022237 1 NC_012563.1 hypothetical protein 2022237 7764811 CLM_1960 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804135.1 2022076 D 536232 CDS YP_002804136.1 226949045 7767916 2022292..2023482 1 NC_012563.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 2023482 aspB 7767916 aspB Clostridium botulinum A2 str. Kyoto aspartate aminotransferase YP_002804136.1 2022292 D 536232 CDS YP_002804137.1 226949046 7766625 complement(2023513..2024379) 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2024379 7766625 CLM_1962 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002804137.1 2023513 R 536232 CDS YP_002804138.1 226949047 7765748 complement(2024461..2025519) 1 NC_012563.1 identified by match to protein family HMM TIGR02906; CotS family spore coat protein 2025519 7765748 CLM_1963 Clostridium botulinum A2 str. Kyoto CotS family spore coat protein YP_002804138.1 2024461 R 536232 CDS YP_002804139.1 226949048 7766258 complement(2025767..2027683) 1 NC_012563.1 these proteins appear to have resulted from a fusion of lytB and rpsA; catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain-containing protein 2027683 7766258 CLM_1964 Clostridium botulinum A2 str. Kyoto 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain-containing protein YP_002804139.1 2025767 R 536232 CDS YP_002804140.1 226949049 7767382 complement(2027747..2028400) 1 NC_012563.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 2028400 cmk 7767382 cmk Clostridium botulinum A2 str. Kyoto cytidylate kinase YP_002804140.1 2027747 R 536232 CDS YP_002804141.1 226949050 7766168 complement(2028476..2028850) 1 NC_012563.1 identified by match to protein family HMM PF07736; match to protein family HMM TIGR01796; chorismate mutase 2028850 aroH 7766168 aroH Clostridium botulinum A2 str. Kyoto chorismate mutase YP_002804141.1 2028476 R 536232 CDS YP_002804142.1 226949051 7767342 complement(2028847..2030070) 1 NC_012563.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275; pyridine nucleotide-disulfide oxidoreductase family protein 2030070 7767342 CLM_1967 Clostridium botulinum A2 str. Kyoto pyridine nucleotide-disulfide oxidoreductase family protein YP_002804142.1 2028847 R 536232 CDS YP_002804143.1 226949052 7764938 complement(2030364..2031629) 1 NC_012563.1 identified by match to protein family HMM PF00208; match to protein family HMM PF02812; glutamate dehydrogenase, NAD-specific 2031629 gluD 7764938 gluD Clostridium botulinum A2 str. Kyoto glutamate dehydrogenase, NAD-specific YP_002804143.1 2030364 R 536232 CDS YP_002804144.1 226949053 7766131 complement(2031863..2032747) 1 NC_012563.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator 2032747 7766131 CLM_1969 Clostridium botulinum A2 str. Kyoto RpiR family transcriptional regulator YP_002804144.1 2031863 R 536232 CDS YP_002804145.1 226949054 7766704 complement(2033129..2033839) 1 NC_012563.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal large subunit pseudouridine synthase B 2033839 rluB 7766704 rluB Clostridium botulinum A2 str. Kyoto ribosomal large subunit pseudouridine synthase B YP_002804145.1 2033129 R 536232 CDS YP_002804146.1 226949055 7764578 complement(2034272..2035561) 1 NC_012563.1 hypothetical protein 2035561 7764578 CLM_1971 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804146.1 2034272 R 536232 CDS YP_002804147.1 226949056 7765502 complement(2035659..2036939) 1 NC_012563.1 identified by match to protein family HMM PF06354; hypothetical protein 2036939 7765502 CLM_1972 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804147.1 2035659 R 536232 CDS YP_002804148.1 226949057 7766373 complement(2037234..2038637) 1 NC_012563.1 identified by match to protein family HMM PF00535; group 2 family glycosyl transferase 2038637 7766373 CLM_1973 Clostridium botulinum A2 str. Kyoto group 2 family glycosyl transferase YP_002804148.1 2037234 R 536232 CDS YP_002804149.1 226949058 7764952 2039007..2039198 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2039198 7764952 CLM_1974 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804149.1 2039007 D 536232 CDS YP_002804150.1 226949059 7767354 2039587..2041608 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis protein 2041608 7767354 CLM_1975 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002804150.1 2039587 D 536232 CDS YP_002804151.1 226949060 7765353 complement(2041652..2042338) 1 NC_012563.1 identified by match to protein family HMM PF02683; putative cytochrome c-type biogenesis protein 2042338 7765353 CLM_1976 Clostridium botulinum A2 str. Kyoto putative cytochrome c-type biogenesis protein YP_002804151.1 2041652 R 536232 CDS YP_002804152.1 226949061 7764273 complement(2042340..2042771) 1 NC_012563.1 identified by match to protein family HMM PF00085; thioredoxin family protein 2042771 7764273 CLM_1977 Clostridium botulinum A2 str. Kyoto thioredoxin family protein YP_002804152.1 2042340 R 536232 CDS YP_002804153.1 226949062 7767446 complement(2042886..2043722) 1 NC_012563.1 identified by match to protein family HMM PF00795; hydrolase, carbon-nitrogen family 2043722 7767446 CLM_1978 Clostridium botulinum A2 str. Kyoto hydrolase, carbon-nitrogen family YP_002804153.1 2042886 R 536232 CDS YP_002804154.1 226949063 7767825 complement(2043853..2044407) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2044407 7767825 CLM_1979 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804154.1 2043853 R 536232 CDS YP_002804155.1 226949064 7765818 2044819..2046252 1 NC_012563.1 identified by match to protein family HMM PF00999; match to protein family HMM PF02080; CPA2 family transporter 2046252 7765818 CLM_1980 Clostridium botulinum A2 str. Kyoto CPA2 family transporter YP_002804155.1 2044819 D 536232 CDS YP_002804156.1 226949065 7764734 complement(2046377..2046721) 1 NC_012563.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778; 4-carboxymuconolactone decarboxylase 2046721 pcaC 7764734 pcaC Clostridium botulinum A2 str. Kyoto 4-carboxymuconolactone decarboxylase YP_002804156.1 2046377 R 536232 CDS YP_002804157.1 226949066 7767611 complement(2046859..2047374) 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2047374 7767611 CLM_1982 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002804157.1 2046859 R 536232 CDS YP_002804158.1 226949067 7766245 complement(2047559..2048053) 1 NC_012563.1 putative lipoprotein 2048053 7766245 CLM_1983 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002804158.1 2047559 R 536232 CDS YP_002804159.1 226949068 7768078 complement(2048287..2048598) 1 NC_012563.1 identified by match to protein family HMM PF01906; hypothetical protein 2048598 7768078 CLM_1984 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804159.1 2048287 R 536232 CDS YP_002804160.1 226949069 7764251 complement(2048579..2048812) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2048812 7764251 CLM_1985 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804160.1 2048579 R 536232 CDS YP_002804161.1 226949070 7764793 2048946..2049188 1 NC_012563.1 hypothetical protein 2049188 7764793 CLM_1986 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804161.1 2048946 D 536232 CDS YP_002804162.1 226949071 7765881 2049191..2050915 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF02906; match to protein family HMM PF04060; match to protein family HMM TIGR00229; sensory box-containing [Fe] hydrogenase 2050915 7765881 CLM_1987 Clostridium botulinum A2 str. Kyoto sensory box-containing [Fe] hydrogenase YP_002804162.1 2049191 D 536232 CDS YP_002804163.1 226949072 7765337 2050912..2052081 1 NC_012563.1 identified by match to protein family HMM PF07228; sporulation domain-containing protein 2052081 7765337 CLM_1988 Clostridium botulinum A2 str. Kyoto sporulation domain-containing protein YP_002804163.1 2050912 D 536232 CDS YP_002804164.1 226949073 7766476 2052217..2053956 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF02906; match to protein family HMM PF04060; match to protein family HMM TIGR00229; sensory box-containing [Fe] hydrogenase 2053956 7766476 CLM_1989 Clostridium botulinum A2 str. Kyoto sensory box-containing [Fe] hydrogenase YP_002804164.1 2052217 D 536232 CDS YP_002804165.1 226949074 7764211 complement(2054309..2055313) 1 NC_012563.1 identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124; hydrogenase expression/formation protein HypE 2055313 hypE 7764211 hypE Clostridium botulinum A2 str. Kyoto hydrogenase expression/formation protein HypE YP_002804165.1 2054309 R 536232 CDS YP_002804166.1 226949075 7765289 complement(2055481..2056554) 1 NC_012563.1 identified by match to protein family HMM PF01924; hydrogenase expression/formation protein HypD 2056554 hypD 7765289 hypD Clostridium botulinum A2 str. Kyoto hydrogenase expression/formation protein HypD YP_002804166.1 2055481 R 536232 CDS YP_002804167.1 226949076 7766971 complement(2056547..2056774) 1 NC_012563.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074; hydrogenase assembly chaperone HypC/HupF 2056774 hypC 7766971 hypC Clostridium botulinum A2 str. Kyoto hydrogenase assembly chaperone HypC/HupF YP_002804167.1 2056547 R 536232 CDS YP_002804168.1 226949077 7768072 complement(2056737..2059175) 1 NC_012563.1 identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143; [NiFe] hydrogenase maturation protein HypF 2059175 hypF 7768072 hypF Clostridium botulinum A2 str. Kyoto [NiFe] hydrogenase maturation protein HypF YP_002804168.1 2056737 R 536232 CDS YP_002804169.1 226949078 7767398 complement(2059159..2059419) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative; hypothetical protein 2059419 7767398 CLM_1994 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804169.1 2059159 R 536232 CDS YP_002804170.1 226949079 7766228 complement(2059674..2060189) 1 NC_012563.1 identified by match to protein family HMM PF00173; heme/steroid binding domain-containing protein 2060189 7766228 CLM_1995 Clostridium botulinum A2 str. Kyoto heme/steroid binding domain-containing protein YP_002804170.1 2059674 R 536232 CDS YP_002804171.1 226949080 7768089 complement(2060349..2060765) 1 NC_012563.1 identified by match to protein family HMM PF01750; match to protein family HMM TIGR00072; hydrogenase maturation protease 2060765 7768089 CLM_1996 Clostridium botulinum A2 str. Kyoto hydrogenase maturation protease YP_002804171.1 2060349 R 536232 CDS YP_002804172.1 226949081 7765335 complement(2060798..2062213) 1 NC_012563.1 identified by match to protein family HMM PF00374; [Ni/Fe] hydrogenase large subunit 2062213 hupL 7765335 hupL Clostridium botulinum A2 str. Kyoto [Ni/Fe] hydrogenase large subunit YP_002804172.1 2060798 R 536232 CDS YP_002804173.1 226949082 7765876 complement(2062315..2063187) 1 NC_012563.1 identified by match to protein family HMM PF01058; match to protein family HMM TIGR00391; [Ni/Fe] hydrogenase small subunit 2063187 hupS 7765876 hupS Clostridium botulinum A2 str. Kyoto [Ni/Fe] hydrogenase small subunit YP_002804173.1 2062315 R 536232 CDS YP_002804174.1 226949083 7764747 2063455..2064156 1 NC_012563.1 TraX family protein 2064156 7764747 CLM_1999 Clostridium botulinum A2 str. Kyoto TraX family protein YP_002804174.1 2063455 D 536232 CDS YP_002804175.1 226949084 7766423 2064577..2064744 1 NC_012563.1 hypothetical protein 2064744 7766423 CLM_2000 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804175.1 2064577 D 536232 CDS YP_002804176.1 226949085 7765802 complement(2065420..2068626) 1 NC_012563.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 2068626 carB 7765802 carB Clostridium botulinum A2 str. Kyoto carbamoyl phosphate synthase large subunit YP_002804176.1 2065420 R 536232 CDS YP_002804177.1 226949086 7764312 complement(2068654..2069703) 1 NC_012563.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 2069703 carA 7764312 carA Clostridium botulinum A2 str. Kyoto carbamoyl phosphate synthase small subunit YP_002804177.1 2068654 R 536232 CDS YP_002804178.1 226949087 7767567 2070219..2070386 1 NC_012563.1 hypothetical protein 2070386 7767567 CLM_2003 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804178.1 2070219 D 536232 CDS YP_002804179.1 226949088 7767671 2070988..2071611 1 NC_012563.1 identified by match to protein family HMM PF01061; ABC transporter permease 2071611 7767671 CLM_2004 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002804179.1 2070988 D 536232 CDS YP_002804180.1 226949089 7767026 complement(2071854..2072054) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 2072054 7767026 CLM_2005 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804180.1 2071854 R 536232 CDS YP_002804181.1 226949090 7765006 complement(2072255..2073811) 1 NC_012563.1 identified by match to protein family HMM PF00005; drug resistance ABC transporter RA1 family, ATP-binding protein 2073811 7765006 CLM_2006 Clostridium botulinum A2 str. Kyoto drug resistance ABC transporter RA1 family, ATP-binding protein YP_002804181.1 2072255 R 536232 CDS YP_002804182.1 226949091 7767945 complement(2074173..2075906) 1 NC_012563.1 identified by similarity to SP:P29166; match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512; iron hydrogenase 1 2075906 7767945 CLM_2007 Clostridium botulinum A2 str. Kyoto iron hydrogenase 1 YP_002804182.1 2074173 R 536232 CDS YP_002804183.1 226949092 7767323 complement(2075926..2077821) 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01512; putative [Fe] hydrogenase, electron-transfer subunit 2077821 7767323 CLM_2008 Clostridium botulinum A2 str. Kyoto putative [Fe] hydrogenase, electron-transfer subunit YP_002804183.1 2075926 R 536232 CDS YP_002804184.1 226949093 7766172 complement(2077833..2078312) 1 NC_012563.1 identified by match to protein family HMM PF01257; putative Fe] hydrogenase, electron-transfer subunit 2078312 7766172 CLM_2009 Clostridium botulinum A2 str. Kyoto putative Fe] hydrogenase, electron-transfer subunit YP_002804184.1 2077833 R 536232 CDS YP_002804185.1 226949094 7764200 complement(2078787..2079974) 1 NC_012563.1 identified by match to protein family HMM PF00999; CPA2 family transporter 2079974 7764200 CLM_2010 Clostridium botulinum A2 str. Kyoto CPA2 family transporter YP_002804185.1 2078787 R 536232 CDS YP_002804186.1 226949095 7767568 complement(2080234..2081112) 1 NC_012563.1 identified by match to protein family HMM PF03747; ADP-ribosylglycohydrolase family protein 2081112 7767568 CLM_2011 Clostridium botulinum A2 str. Kyoto ADP-ribosylglycohydrolase family protein YP_002804186.1 2080234 R 536232 CDS YP_002804187.1 226949096 7766447 2081352..2082446 1 NC_012563.1 identified by match to protein family HMM PF01594; hypothetical protein 2082446 7766447 CLM_2012 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804187.1 2081352 D 536232 CDS YP_002804188.1 226949097 7765862 complement(2082556..2083692) 1 NC_012563.1 identified by match to protein family HMM PF00768; putative serine-type D-Ala-D-Ala carboxypeptidase 2083692 7765862 CLM_2013 Clostridium botulinum A2 str. Kyoto putative serine-type D-Ala-D-Ala carboxypeptidase YP_002804188.1 2082556 R 536232 CDS YP_002804189.1 226949098 7766571 2083876..2084388 1 NC_012563.1 hypothetical protein 2084388 7766571 CLM_2014 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804189.1 2083876 D 536232 CDS YP_002804190.1 226949099 7767413 2084456..2084896 1 NC_012563.1 identified by match to protein family HMM PF09579; match to protein family HMM TIGR02874; sporulation protein YtfJ 2084896 ytfJ 7767413 ytfJ Clostridium botulinum A2 str. Kyoto sporulation protein YtfJ YP_002804190.1 2084456 D 536232 CDS YP_002804191.1 226949100 7764864 complement(2084957..2085538) 1 NC_012563.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 2085538 scpB 7764864 scpB Clostridium botulinum A2 str. Kyoto segregation and condensation protein B YP_002804191.1 2084957 R 536232 CDS YP_002804192.1 226949101 7765703 complement(2085531..2086277) 1 NC_012563.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 2086277 scpA 7765703 scpA Clostridium botulinum A2 str. Kyoto segregation and condensation protein A YP_002804192.1 2085531 R 536232 CDS YP_002804193.1 226949102 7767901 complement(2087054..2088277) 1 NC_012563.1 identified by similarity to SP:P38422; match to protein family HMM PF00768; match to protein family HMM PF07943; serine-type D-Ala-D-Ala carboxypeptidase 2088277 dacF 7767901 dacF Clostridium botulinum A2 str. Kyoto serine-type D-Ala-D-Ala carboxypeptidase YP_002804193.1 2087054 R 536232 CDS YP_002804194.1 226949103 7766102 complement(2088400..2089122) 1 NC_012563.1 hypothetical protein 2089122 7766102 CLM_2021 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804194.1 2088400 R 536232 CDS YP_002804195.1 226949104 7766958 complement(2089281..2090363) 1 NC_012563.1 identified by match to protein family HMM PF03372; endonuclease/exonuclease/phosphatase family protein 2090363 7766958 CLM_2022 Clostridium botulinum A2 str. Kyoto endonuclease/exonuclease/phosphatase family protein YP_002804195.1 2089281 R 536232 CDS YP_002804196.1 226949105 7766298 complement(2090481..2090729) 1 NC_012563.1 hypothetical protein 2090729 7766298 CLM_2023 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804196.1 2090481 R 536232 CDS YP_002804197.1 226949106 7765039 complement(2090836..2092140) 1 NC_012563.1 identified by similarity to SP:P39142; match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831; match to protein family HMM TIGR02644; pyrimidine-nucleoside phosphorylase 2092140 pdp 7765039 pdp Clostridium botulinum A2 str. Kyoto pyrimidine-nucleoside phosphorylase YP_002804197.1 2090836 R 536232 CDS YP_002804198.1 226949107 7764488 complement(2092426..2093241) 1 NC_012563.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 2093241 punA 7764488 punA Clostridium botulinum A2 str. Kyoto purine nucleoside phosphorylase YP_002804198.1 2092426 R 536232 CDS YP_002804199.1 226949108 7765593 complement(2093279..2094154) 1 NC_012563.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM TIGR02225; tyrosine recombinase XerD 2094154 xerD 7765593 xerD Clostridium botulinum A2 str. Kyoto tyrosine recombinase XerD YP_002804199.1 2093279 R 536232 CDS YP_002804200.1 226949109 7767050 complement(2094206..2094433) 1 NC_012563.1 hypothetical protein 2094433 7767050 CLM_2027 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804200.1 2094206 R 536232 CDS YP_002804201.1 226949110 7767800 complement(2094424..2095077) 1 NC_012563.1 identified by match to protein family HMM PF01944; match to protein family HMM TIGR02831; stage II sporulation protein M 2095077 spoIIM 7767800 spoIIM Clostridium botulinum A2 str. Kyoto stage II sporulation protein M YP_002804201.1 2094424 R 536232 CDS YP_002804202.1 226949111 7764939 2095118..2095231 1 NC_012563.1 hypothetical protein 2095231 7764939 CLM_2029 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804202.1 2095118 D 536232 CDS YP_002804203.1 226949112 7765997 complement(2095284..2095820) 1 NC_012563.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052; NUDIX family hydrolase 2095820 7765997 CLM_2030 Clostridium botulinum A2 str. Kyoto NUDIX family hydrolase YP_002804203.1 2095284 R 536232 CDS YP_002804204.1 226949113 7766214 complement(2096314..2097840) 1 NC_012563.1 identified by match to protein family HMM PF00324; amino acid permease family protein 2097840 7766214 CLM_2031 Clostridium botulinum A2 str. Kyoto amino acid permease family protein YP_002804204.1 2096314 R 536232 CDS YP_002804205.1 226949114 7767358 complement(2098656..2099414) 1 NC_012563.1 identified by match to protein family HMM PF00877; nlpC/P60 family protein 2099414 7767358 CLM_2032 Clostridium botulinum A2 str. Kyoto nlpC/P60 family protein YP_002804205.1 2098656 R 536232 CDS YP_002804206.1 226949115 7764487 complement(2100014..2100127) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2100127 7764487 CLM_2033 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804206.1 2100014 R 536232 CDS YP_002804207.1 226949116 7765456 complement(2101449..2102027) 1 NC_012563.1 hypothetical protein 2102027 7765456 CLM_2034 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804207.1 2101449 R 536232 CDS YP_002804208.1 226949117 7766371 complement(2102706..2103293) 1 NC_012563.1 hypothetical protein 2103293 7766371 CLM_2035 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804208.1 2102706 R 536232 CDS YP_002804209.1 226949118 7767225 complement(2103422..2104180) 1 NC_012563.1 identified by match to protein family HMM PF01520; match to protein family HMM PF08239; N-acetylmuramoyl-L-alanine amidase 2104180 7767225 CLM_2036 Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase YP_002804209.1 2103422 R 536232 CDS YP_002804210.1 226949119 7767014 complement(2104180..2104353) 1 NC_012563.1 hypothetical protein 2104353 7767014 CLM_2037 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804210.1 2104180 R 536232 CDS YP_002804211.1 226949120 7768087 complement(2104355..2104579) 1 NC_012563.1 hypothetical protein 2104579 7768087 CLM_2038 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804211.1 2104355 R 536232 CDS YP_002804212.1 226949121 7764436 complement(2104791..2105270) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2105270 7764436 CLM_2039 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804212.1 2104791 R 536232 CDS YP_002804213.1 226949122 7765230 2105519..2105926 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2105926 7765230 CLM_2040 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804213.1 2105519 D 536232 CDS YP_002804214.1 226949123 7766659 complement(2106021..2106188) 1 NC_012563.1 hypothetical protein 2106188 7766659 CLM_2041 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804214.1 2106021 R 536232 CDS YP_002804215.1 226949124 7767539 complement(2106190..2106516) 1 NC_012563.1 hypothetical protein 2106516 7767539 CLM_2042 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804215.1 2106190 R 536232 CDS YP_002804216.1 226949125 7765907 complement(2106528..2107985) 1 NC_012563.1 hypothetical protein 2107985 7765907 CLM_2043 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804216.1 2106528 R 536232 CDS YP_002804217.1 226949126 7765820 complement(2107992..2109149) 1 NC_012563.1 hypothetical protein 2109149 7765820 CLM_2044 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804217.1 2107992 R 536232 CDS YP_002804218.1 226949127 7766679 complement(2109153..2110022) 1 NC_012563.1 hypothetical protein 2110022 7766679 CLM_2045 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804218.1 2109153 R 536232 CDS YP_002804219.1 226949128 7767969 complement(2110038..2113964) 1 NC_012563.1 identified by match to protein family HMM TIGR01760; phage tail tape measure protein, family 2113964 7767969 CLM_2046 Clostridium botulinum A2 str. Kyoto phage tail tape measure protein, family YP_002804219.1 2110038 R 536232 CDS YP_002804220.1 226949129 7767150 complement(2114021..2114140) 1 NC_012563.1 hypothetical protein 2114140 7767150 CLM_2047 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804220.1 2114021 R 536232 CDS YP_002804221.1 226949130 7767918 complement(2114254..2114646) 1 NC_012563.1 hypothetical protein 2114646 7767918 CLM_2048 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804221.1 2114254 R 536232 CDS YP_002804222.1 226949131 7764446 complement(2114704..2115285) 1 NC_012563.1 identified by match to protein family HMM TIGR01603; phage major tail protein, Phi13 family 2115285 7764446 CLM_2049 Clostridium botulinum A2 str. Kyoto phage major tail protein, Phi13 family YP_002804222.1 2114704 R 536232 CDS YP_002804223.1 226949132 7767844 complement(2115349..2115705) 1 NC_012563.1 hypothetical protein 2115705 7767844 CLM_2050 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804223.1 2115349 R 536232 CDS YP_002804224.1 226949133 7767472 complement(2115721..2116080) 1 NC_012563.1 identified by match to protein family HMM TIGR01725; phage protein, HK97 gp10 family 2116080 7767472 CLM_2051 Clostridium botulinum A2 str. Kyoto phage protein, HK97 gp10 family YP_002804224.1 2115721 R 536232 CDS YP_002804225.1 226949134 7764625 complement(2116081..2116449) 1 NC_012563.1 identified by match to protein family HMM TIGR01563; phage head-tail adaptor protein 2116449 7764625 CLM_2052 Clostridium botulinum A2 str. Kyoto phage head-tail adaptor protein YP_002804225.1 2116081 R 536232 CDS YP_002804226.1 226949135 7765357 complement(2116439..2116732) 1 NC_012563.1 identified by match to protein family HMM TIGR01560; hypothetical protein 2116732 7765357 CLM_2053 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804226.1 2116439 R 536232 CDS YP_002804227.1 226949136 7766067 complement(2116817..2118049) 1 NC_012563.1 identified by match to protein family HMM PF05065; match to protein family HMM TIGR01554; phage major capsid protein, HK97 family 2118049 7766067 CLM_2054 Clostridium botulinum A2 str. Kyoto phage major capsid protein, HK97 family YP_002804227.1 2116817 R 536232 CDS YP_002804228.1 226949137 7767426 complement(2118102..2118845) 1 NC_012563.1 identified by match to protein family HMM PF00574; serine protease 2118845 7767426 CLM_2055 Clostridium botulinum A2 str. Kyoto serine protease YP_002804228.1 2118102 R 536232 CDS YP_002804229.1 226949138 7767796 complement(2118838..2120088) 1 NC_012563.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; phage portal protein, HK97 family 2120088 7767796 CLM_2056 Clostridium botulinum A2 str. Kyoto phage portal protein, HK97 family YP_002804229.1 2118838 R 536232 CDS YP_002804230.1 226949139 7767558 complement(2120132..2120293) 1 NC_012563.1 hypothetical protein 2120293 7767558 CLM_2057 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804230.1 2120132 R 536232 CDS YP_002804231.1 226949140 7766411 complement(2120338..2122056) 1 NC_012563.1 identified by match to protein family HMM PF03354; putative phage terminase large subunit 2122056 7766411 CLM_2058 Clostridium botulinum A2 str. Kyoto putative phage terminase large subunit YP_002804231.1 2120338 R 536232 CDS YP_002804232.1 226949141 7765381 complement(2122049..2122510) 1 NC_012563.1 identified by match to protein family HMM PF05119; match to protein family HMM TIGR01558; phage terminase small subunit, P27 family 2122510 7765381 CLM_2059 Clostridium botulinum A2 str. Kyoto phage terminase small subunit, P27 family YP_002804232.1 2122049 R 536232 CDS YP_002804233.1 226949142 7764295 complement(2122646..2123050) 1 NC_012563.1 identified by match to protein family HMM PF01844; HNH endonuclease domain-containing protein 2123050 7764295 CLM_2060 Clostridium botulinum A2 str. Kyoto HNH endonuclease domain-containing protein YP_002804233.1 2122646 R 536232 CDS YP_002804234.1 226949143 7768115 complement(2123118..2123282) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2123282 7768115 CLM_2061 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804234.1 2123118 R 536232 CDS YP_002804235.1 226949144 7766767 complement(2123360..2124691) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2124691 7766767 CLM_2062 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804235.1 2123360 R 536232 CDS YP_002804236.1 226949145 7765893 complement(2124878..2125438) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2125438 7765893 CLM_2063 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804236.1 2124878 R 536232 CDS YP_002804237.1 226949146 7766505 complement(2125608..2125829) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2125829 7766505 CLM_2064 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804237.1 2125608 R 536232 CDS YP_002804238.1 226949147 7765898 complement(2125845..2127257) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2127257 7765898 CLM_2065 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804238.1 2125845 R 536232 CDS YP_002804239.1 226949148 7764385 complement(2127299..2127508) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2127508 7764385 CLM_2066 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804239.1 2127299 R 536232 CDS YP_002804240.1 226949149 7764801 complement(2127584..2127904) 1 NC_012563.1 hypothetical protein 2127904 7764801 CLM_2067 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804240.1 2127584 R 536232 CDS YP_002804241.1 226949150 7767752 complement(2127955..2128209) 1 NC_012563.1 hypothetical protein 2128209 7767752 CLM_2068 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804241.1 2127955 R 536232 CDS YP_002804242.1 226949151 7767642 complement(2128283..2128804) 1 NC_012563.1 identified by match to protein family HMM PF01541; GIY-YIG domain-containing protein 2128804 7767642 CLM_2069 Clostridium botulinum A2 str. Kyoto GIY-YIG domain-containing protein YP_002804242.1 2128283 R 536232 CDS YP_002804243.1 226949152 7766437 complement(2129199..2129636) 1 NC_012563.1 hypothetical protein 2129636 7766437 CLM_2070 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804243.1 2129199 R 536232 CDS YP_002804244.1 226949153 7764274 complement(2129668..2130345) 1 NC_012563.1 hypothetical protein 2130345 7764274 CLM_2071 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804244.1 2129668 R 536232 CDS YP_002804245.1 226949154 7768000 complement(2130648..2133542) 1 NC_012563.1 hypothetical protein 2133542 7768000 CLM_2072 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804245.1 2130648 R 536232 CDS YP_002804246.1 226949155 7766634 complement(2133661..2133825) 1 NC_012563.1 hypothetical protein 2133825 7766634 CLM_2073 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804246.1 2133661 R 536232 CDS YP_002804247.1 226949156 7767279 complement(2134183..2135319) 1 NC_012563.1 hypothetical protein 2135319 7767279 CLM_2074 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804247.1 2134183 R 536232 CDS YP_002804248.1 226949157 7766486 complement(2135364..2136317) 1 NC_012563.1 hypothetical protein 2136317 7766486 CLM_2075 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804248.1 2135364 R 536232 CDS YP_002804249.1 226949158 7765358 complement(2136388..2137194) 1 NC_012563.1 hypothetical protein 2137194 7765358 CLM_2076 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804249.1 2136388 R 536232 CDS YP_002804250.1 226949159 7765469 complement(2137245..2137403) 1 NC_012563.1 hypothetical protein 2137403 7765469 CLM_2077 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804250.1 2137245 R 536232 CDS YP_002804251.1 226949160 7764270 complement(2137793..2138011) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2138011 7764270 CLM_2078 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804251.1 2137793 R 536232 CDS YP_002804252.1 226949161 7767599 complement(2138132..2138788) 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 2138788 7767599 CLM_2079 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002804252.1 2138132 R 536232 CDS YP_002804253.1 226949162 7766450 complement(2138920..2139078) 1 NC_012563.1 hypothetical protein 2139078 7766450 CLM_2080 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804253.1 2138920 R 536232 CDS YP_002804254.1 226949163 7765780 complement(2139071..2139400) 1 NC_012563.1 hypothetical protein 2139400 7765780 CLM_2081 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804254.1 2139071 R 536232 CDS YP_002804255.1 226949164 7764737 2139680..2139883 1 NC_012563.1 hypothetical protein 2139883 7764737 CLM_2082 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804255.1 2139680 D 536232 CDS YP_002804256.1 226949165 7767181 2140007..2141428 1 NC_012563.1 identified by match to protein family HMM PF00589; match to protein family HMM PF04313; phage integrase family site-specific recombinase 2141428 7767181 CLM_2083 Clostridium botulinum A2 str. Kyoto phage integrase family site-specific recombinase YP_002804256.1 2140007 D 536232 CDS YP_002804257.1 226949166 7764508 complement(2141509..2141733) 1 NC_012563.1 hypothetical protein 2141733 7764508 CLM_2084 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804257.1 2141509 R 536232 CDS YP_002804258.1 226949167 7767710 complement(2141784..2142467) 1 NC_012563.1 hypothetical protein 2142467 7767710 CLM_2085 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804258.1 2141784 R 536232 CDS YP_002804259.1 226949168 7767114 complement(2142915..2143403) 1 NC_012563.1 hypothetical protein 2143403 7767114 CLM_2086 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804259.1 2142915 R 536232 CDS YP_002804260.1 226949169 7767984 complement(2143403..2144395) 1 NC_012563.1 identified by similarity to SP:P46352; match to protein family HMM PF00589; match to protein family HMM PF02899; phage integrase family site-specific recombinase 2144395 7767984 CLM_2087 Clostridium botulinum A2 str. Kyoto phage integrase family site-specific recombinase YP_002804260.1 2143403 R 536232 CDS YP_002804261.1 226949170 7767223 complement(2144531..2145352) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF08769; match to protein family HMM TIGR02875; sporulation transcription factor Spo0A 2145352 spo0A 7767223 spo0A Clostridium botulinum A2 str. Kyoto sporulation transcription factor Spo0A YP_002804261.1 2144531 R 536232 CDS YP_002804262.1 226949171 7766379 complement(2145782..2147008) 1 NC_012563.1 identified by match to protein family HMM PF05580; match to protein family HMM TIGR02860; stage IV sporulation protein B 2147008 spoIVB 7766379 spoIVB Clostridium botulinum A2 str. Kyoto stage IV sporulation protein B YP_002804262.1 2145782 R 536232 CDS YP_002804263.1 226949172 7765348 complement(2147430..2148326) 1 NC_012563.1 identified by match to protein family HMM PF04204; match to protein family HMM TIGR01001; homoserine O-succinyltransferase 2148326 metA 7765348 metA Clostridium botulinum A2 str. Kyoto homoserine O-succinyltransferase YP_002804263.1 2147430 R 536232 CDS YP_002804264.1 226949173 7767445 complement(2148353..2149579) 1 NC_012563.1 identified by match to protein family HMM PF00742; match to protein family HMM PF03447; homoserine dehydrogenase 2149579 hom 7767445 hom Clostridium botulinum A2 str. Kyoto homoserine dehydrogenase YP_002804264.1 2148353 R 536232 CDS YP_002804265.1 226949174 7766533 complement(2149619..2150899) 1 NC_012563.1 identified by match to protein family HMM PF01053; match to protein family HMM TIGR01326; O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein 2150899 7766533 CLM_2092 Clostridium botulinum A2 str. Kyoto O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein YP_002804265.1 2149619 R 536232 CDS YP_002804266.1 226949175 7765668 complement(2151198..2152901) 1 NC_012563.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634; DNA repair protein recN 2152901 recN 7765668 recN Clostridium botulinum A2 str. Kyoto DNA repair protein recN YP_002804266.1 2151198 R 536232 CDS YP_002804267.1 226949176 7765788 complement(2152914..2153366) 1 NC_012563.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 2153366 argR 7765788 argR Clostridium botulinum A2 str. Kyoto arginine repressor YP_002804267.1 2152914 R 536232 CDS YP_002804268.1 226949177 7767401 complement(2153368..2154213) 1 NC_012563.1 identified by match to protein family HMM PF01513; ATP-NAD kinase 2154213 ppnK 7767401 ppnK Clostridium botulinum A2 str. Kyoto ATP-NAD kinase YP_002804268.1 2153368 R 536232 CDS YP_002804269.1 226949178 7764220 complement(2154213..2155034) 1 NC_012563.1 identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478; putative hemolysin A 2155034 7764220 CLM_2097 Clostridium botulinum A2 str. Kyoto putative hemolysin A YP_002804269.1 2154213 R 536232 CDS YP_002804270.1 226949179 7765347 complement(2155056..2156924) 1 NC_012563.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 2156924 dxs 7765347 dxs Clostridium botulinum A2 str. Kyoto 1-deoxy-D-xylulose-5-phosphate synthase YP_002804270.1 2155056 R 536232 CDS YP_002804271.1 226949180 7766186 complement(2156925..2157494) 1 NC_012563.1 hypothetical protein 2157494 7766186 CLM_2099 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804271.1 2156925 R 536232 CDS YP_002804272.1 226949181 7767495 complement(2158297..2159169) 1 NC_012563.1 identified by match to protein family HMM PF00348; geranyltranstransferase 2159169 ispA 7767495 ispA Clostridium botulinum A2 str. Kyoto geranyltranstransferase YP_002804272.1 2158297 R 536232 CDS YP_002804273.1 226949182 7765489 complement(2159294..2159509) 1 NC_012563.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 2159509 xseB 7765489 xseB Clostridium botulinum A2 str. Kyoto exodeoxyribonuclease VII small subunit YP_002804273.1 2159294 R 536232 CDS YP_002804274.1 226949183 7765874 complement(2159632..2160837) 1 NC_012563.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2160837 xseA 7765874 xseA Clostridium botulinum A2 str. Kyoto exodeoxyribonuclease VII large subunit YP_002804274.1 2159632 R 536232 CDS YP_002804275.1 226949184 7766691 complement(2160908..2161339) 1 NC_012563.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 2161339 nusB 7766691 nusB Clostridium botulinum A2 str. Kyoto transcription antitermination protein NusB YP_002804275.1 2160908 R 536232 CDS YP_002804276.1 226949185 7768051 complement(2161478..2161873) 1 NC_012563.1 identified by match to protein family HMM PF03780; alkaline shock protein 2161873 asp 7768051 asp Clostridium botulinum A2 str. Kyoto alkaline shock protein YP_002804276.1 2161478 R 536232 CDS YP_002804277.1 226949186 7766829 complement(2161955..2162479) 1 NC_012563.1 stage III sporulation protein AH 2162479 7766829 CLM_2105 Clostridium botulinum A2 str. Kyoto stage III sporulation protein AH YP_002804277.1 2161955 R 536232 CDS YP_002804278.1 226949187 7767952 complement(2162541..2163137) 1 NC_012563.1 identified by match to protein family HMM TIGR02830; stage III sporulation protein AG 2163137 7767952 CLM_2106 Clostridium botulinum A2 str. Kyoto stage III sporulation protein AG YP_002804278.1 2162541 R 536232 CDS YP_002804279.1 226949188 7764549 complement(2163275..2163865) 1 NC_012563.1 identified by match to protein family HMM PF09581; match to protein family HMM TIGR02896; stage III sporulation protein AF 2163865 spoIIIAF 7764549 spoIIIAF Clostridium botulinum A2 str. Kyoto stage III sporulation protein AF YP_002804279.1 2163275 R 536232 CDS YP_002804280.1 226949189 7765678 complement(2163901..2165064) 1 NC_012563.1 identified by match to protein family HMM PF09546; match to protein family HMM TIGR02829; stage III sporulation protein AE 2165064 7765678 CLM_2108 Clostridium botulinum A2 str. Kyoto stage III sporulation protein AE YP_002804280.1 2163901 R 536232 CDS YP_002804281.1 226949190 7766564 complement(2165073..2165456) 1 NC_012563.1 identified by match to protein family HMM PF09555; match to protein family HMM TIGR02849; stage III sporulation protein AD 2165456 7766564 CLM_2109 Clostridium botulinum A2 str. Kyoto stage III sporulation protein AD YP_002804281.1 2165073 R 536232 CDS YP_002804282.1 226949191 7767192 complement(2165483..2165680) 1 NC_012563.1 identified by match to protein family HMM PF06686; match to protein family HMM TIGR02848; stage III sporulation protein AC 2165680 7767192 CLM_2110 Clostridium botulinum A2 str. Kyoto stage III sporulation protein AC YP_002804282.1 2165483 R 536232 CDS YP_002804283.1 226949192 7764765 complement(2165723..2166241) 1 NC_012563.1 necessary for complete engulfment of forespore; stage III sporulation protein SpoAB 2166241 7764765 CLM_2111 Clostridium botulinum A2 str. Kyoto stage III sporulation protein SpoAB YP_002804283.1 2165723 R 536232 CDS YP_002804284.1 226949193 7765478 complement(2166278..2167201) 1 NC_012563.1 identified by match to protein family HMM TIGR02858; stage III sporulation protein AA 2167201 7765478 CLM_2112 Clostridium botulinum A2 str. Kyoto stage III sporulation protein AA YP_002804284.1 2166278 R 536232 CDS YP_002804285.1 226949194 7768110 complement(2167396..2167815) 1 NC_012563.1 hypothetical protein 2167815 7768110 CLM_2113 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804285.1 2167396 R 536232 CDS YP_002804286.1 226949195 7764692 complement(2167856..2168413) 1 NC_012563.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 2168413 efp 7764692 efp Clostridium botulinum A2 str. Kyoto elongation factor P YP_002804286.1 2167856 R 536232 CDS YP_002804287.1 226949196 7766225 complement(2168502..2168945) 1 NC_012563.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 2168945 aroQ 7766225 aroQ Clostridium botulinum A2 str. Kyoto 3-dehydroquinate dehydratase YP_002804287.1 2168502 R 536232 CDS YP_002804288.1 226949197 7765584 complement(2169100..2169612) 1 NC_012563.1 identified by match to protein family HMM PF01202; shikimate kinase 2169612 aroK 7765584 aroK Clostridium botulinum A2 str. Kyoto shikimate kinase YP_002804288.1 2169100 R 536232 CDS YP_002804289.1 226949198 7764594 complement(2169746..2170240) 1 NC_012563.1 hypothetical protein 2170240 7764594 CLM_2117 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804289.1 2169746 R 536232 CDS YP_002804290.1 226949199 7766683 complement(2170246..2170692) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2170692 7766683 CLM_2118 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804290.1 2170246 R 536232 CDS YP_002804291.1 226949200 7766016 complement(2170708..2171397) 1 NC_012563.1 hypothetical protein 2171397 7766016 CLM_2119 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804291.1 2170708 R 536232 CDS YP_002804292.1 226949201 7764950 complement(2171425..2171871) 1 NC_012563.1 putative lipoprotein 2171871 7764950 CLM_2120 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002804292.1 2171425 R 536232 CDS YP_002804293.1 226949202 7768002 complement(2171850..2172290) 1 NC_012563.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; prepilin-type N-terminal cleavage/methylation domain-containing protein 2172290 7768002 CLM_2121 Clostridium botulinum A2 str. Kyoto prepilin-type N-terminal cleavage/methylation domain-containing protein YP_002804293.1 2171850 R 536232 CDS YP_002804294.1 226949203 7766163 complement(2172287..2172733) 1 NC_012563.1 identified by match to protein family HMM TIGR02532; prepilin-type N-terminal cleavage/methylation domain-containing protein 2172733 7766163 CLM_2122 Clostridium botulinum A2 str. Kyoto prepilin-type N-terminal cleavage/methylation domain-containing protein YP_002804294.1 2172287 R 536232 CDS YP_002804295.1 226949204 7765513 complement(2172714..2173166) 1 NC_012563.1 hypothetical protein 2173166 7765513 CLM_2123 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804295.1 2172714 R 536232 CDS YP_002804296.1 226949205 7764670 complement(2173568..2173972) 1 NC_012563.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; putative type IV pilin 2173972 7764670 CLM_2124 Clostridium botulinum A2 str. Kyoto putative type IV pilin YP_002804296.1 2173568 R 536232 CDS YP_002804297.1 226949206 7765509 complement(2174158..2175348) 1 NC_012563.1 identified by match to protein family HMM PF00482; type II secretion system protein F 2175348 7765509 CLM_2125 Clostridium botulinum A2 str. Kyoto type II secretion system protein F YP_002804297.1 2174158 R 536232 CDS YP_002804298.1 226949207 7765120 complement(2175493..2177022) 1 NC_012563.1 identified by match to protein family HMM PF00437; match to protein family HMM PF05157; general secretion pathway protein E 2177022 7765120 CLM_2126 Clostridium botulinum A2 str. Kyoto general secretion pathway protein E YP_002804298.1 2175493 R 536232 CDS YP_002804299.1 226949208 7767718 complement(2177095..2177244) 1 NC_012563.1 hypothetical protein 2177244 7767718 CLM_2127 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804299.1 2177095 R 536232 CDS YP_002804300.1 226949209 7766180 complement(2177298..2178371) 1 NC_012563.1 putative lipoprotein 2178371 7766180 CLM_2128 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002804300.1 2177298 R 536232 CDS YP_002804301.1 226949210 7766085 complement(2178372..2179193) 1 NC_012563.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 2179193 dapF 7766085 dapF Clostridium botulinum A2 str. Kyoto diaminopimelate epimerase YP_002804301.1 2178372 R 536232 CDS YP_002804302.1 226949211 7765223 2179447..2181177 1 NC_012563.1 identified by match to protein family HMM PF05670; match to protein family HMM PF05833; fibronectin-binding protein 2181177 7765223 CLM_2130 Clostridium botulinum A2 str. Kyoto fibronectin-binding protein YP_002804302.1 2179447 D 536232 CDS YP_002804303.1 226949212 7764337 2181246..2181986 1 NC_012563.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2181986 truA 7764337 truA Clostridium botulinum A2 str. Kyoto tRNA pseudouridine synthase A YP_002804303.1 2181246 D 536232 CDS YP_002804304.1 226949213 7767452 complement(2182301..2182438) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative; hypothetical protein 2182438 7767452 CLM_2132 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804304.1 2182301 R 536232 CDS YP_002804305.1 226949214 7766578 complement(2182474..2182851) 1 NC_012563.1 identified by match to protein family HMM PF01230; HIT family protein 2182851 7766578 CLM_2133 Clostridium botulinum A2 str. Kyoto HIT family protein YP_002804305.1 2182474 R 536232 CDS YP_002804306.1 226949215 7765388 2183364..2184767 1 NC_012563.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; glutamate decarboxylase 2184767 7765388 CLM_2134 Clostridium botulinum A2 str. Kyoto glutamate decarboxylase YP_002804306.1 2183364 D 536232 CDS YP_002804307.1 226949216 7766731 complement(2185200..2185541) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2185541 7766731 CLM_2135 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804307.1 2185200 R 536232 CDS YP_002804308.1 226949217 7767875 complement(2186046..2187755) 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis protein 2187755 7767875 CLM_2136 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002804308.1 2186046 R 536232 CDS YP_002804309.1 226949218 7764920 complement(2188225..2189799) 1 NC_012563.1 identified by match to protein family HMM PF03415; match to protein family HMM TIGR02806; clostripain 2189799 cloSI 7764920 cloSI Clostridium botulinum A2 str. Kyoto clostripain YP_002804309.1 2188225 R 536232 CDS YP_002804310.1 226949219 7766921 2190279..2190935 1 NC_012563.1 hypothetical protein 2190935 7766921 CLM_2138 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804310.1 2190279 D 536232 CDS YP_002804311.1 226949220 7767293 2190937..2191638 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 2191638 7767293 CLM_2139 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002804311.1 2190937 D 536232 CDS YP_002804312.1 226949221 7764202 2191628..2193541 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 2193541 7764202 CLM_2140 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002804312.1 2191628 D 536232 CDS YP_002804313.1 226949222 7765247 complement(2193942..2194415) 1 NC_012563.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 2194415 msrA 7765247 msrA Clostridium botulinum A2 str. Kyoto methionine sulfoxide reductase A YP_002804313.1 2193942 R 536232 CDS YP_002804314.1 226949223 7766365 complement(2195633..2197096) 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 2197096 7766365 CLM_2142 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002804314.1 2195633 R 536232 CDS YP_002804315.1 226949224 7767505 complement(2197093..2197779) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 2197779 7767505 CLM_2143 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002804315.1 2197093 R 536232 CDS YP_002804316.1 226949225 7767692 complement(2198062..2198838) 1 NC_012563.1 hypothetical protein 2198838 7767692 CLM_2144 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804316.1 2198062 R 536232 CDS YP_002804317.1 226949226 7766684 complement(2198994..2199845) 1 NC_012563.1 ABC transporter permease 2199845 7766684 CLM_2145 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002804317.1 2198994 R 536232 CDS YP_002804318.1 226949227 7764455 complement(2199845..2200588) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2200588 7764455 CLM_2146 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002804318.1 2199845 R 536232 CDS YP_002804319.1 226949228 7765557 2200548..2200721 1 NC_012563.1 hypothetical protein 2200721 7765557 CLM_2147 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804319.1 2200548 D 536232 CDS YP_002804320.1 226949229 7766161 complement(2201178..2203040) 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 2203040 7766161 CLM_2148 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein/permease YP_002804320.1 2201178 R 536232 CDS YP_002804321.1 226949230 7767550 complement(2203037..2205364) 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; putative ABC transporter ATP-binding/permease 2205364 7767550 CLM_2149 Clostridium botulinum A2 str. Kyoto putative ABC transporter ATP-binding/permease YP_002804321.1 2203037 R 536232 CDS YP_002804322.1 226949231 7767493 2205768..2206211 1 NC_012563.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 2206211 7767493 CLM_2150 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002804322.1 2205768 D 536232 CDS YP_002804323.1 226949232 7765859 complement(2206523..2207206) 1 NC_012563.1 identified by match to protein family HMM PF00899; molybdopterin biosynthesis protein MoeB 2207206 moeB 7765859 moeB Clostridium botulinum A2 str. Kyoto molybdopterin biosynthesis protein MoeB YP_002804323.1 2206523 R 536232 CDS YP_002804324.1 226949233 7767149 complement(2207208..2207435) 1 NC_012563.1 identified by match to protein family HMM PF02597; molybdopterin converting factor subunit 1 2207435 moaD 7767149 moaD Clostridium botulinum A2 str. Kyoto molybdopterin converting factor subunit 1 YP_002804324.1 2207208 R 536232 CDS YP_002804325.1 226949234 7767966 complement(2207588..2209405) 1 NC_012563.1 identified by match to protein family HMM PF01314; match to protein family HMM PF02730; aldehyde ferredoxin oxidoreductase 2209405 aor 7767966 aor Clostridium botulinum A2 str. Kyoto aldehyde ferredoxin oxidoreductase YP_002804325.1 2207588 R 536232 CDS YP_002804326.1 226949235 7766135 complement(2209814..2211709) 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM TIGR00229; aor transcriptional regulator 2211709 aorR 7766135 aorR Clostridium botulinum A2 str. Kyoto aor transcriptional regulator YP_002804326.1 2209814 R 536232 CDS YP_002804327.1 226949236 7765226 complement(2211759..2212199) 1 NC_012563.1 identified by match to protein family HMM PF03473; MOSC domain-containing protein 2212199 7765226 CLM_2155 Clostridium botulinum A2 str. Kyoto MOSC domain-containing protein YP_002804327.1 2211759 R 536232 CDS YP_002804328.1 226949237 7767722 complement(2212201..2212680) 1 NC_012563.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 2212680 moaC 7767722 moaC Clostridium botulinum A2 str. Kyoto molybdenum cofactor biosynthesis protein MoaC YP_002804328.1 2212201 R 536232 CDS YP_002804329.1 226949238 7766795 complement(2212684..2213643) 1 NC_012563.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06463; match to protein family HMM TIGR02666; molybdenum cofactor biosynthesis protein A 2213643 moaA 7766795 moaA Clostridium botulinum A2 str. Kyoto molybdenum cofactor biosynthesis protein A YP_002804329.1 2212684 R 536232 CDS YP_002804330.1 226949239 7767109 complement(2213702..2215606) 1 NC_012563.1 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177; LysR family transcriptional regulator 2215606 7767109 CLM_2158 Clostridium botulinum A2 str. Kyoto LysR family transcriptional regulator YP_002804330.1 2213702 R 536232 CDS YP_002804331.1 226949240 7765706 complement(2215618..2216844) 1 NC_012563.1 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177; molybdopterin biosynthesis protein MoeA 2216844 moeA 7765706 moeA Clostridium botulinum A2 str. Kyoto molybdopterin biosynthesis protein MoeA YP_002804331.1 2215618 R 536232 CDS YP_002804332.1 226949241 7764358 complement(2216868..2217356) 1 NC_012563.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; molybdopterin biosynthesis protein Mog 2217356 mog 7764358 mog Clostridium botulinum A2 str. Kyoto molybdopterin biosynthesis protein Mog YP_002804332.1 2216868 R 536232 CDS YP_002804333.1 226949242 7767983 complement(2217451..2218143) 1 NC_012563.1 identified by match to protein family HMM PF00005; tungstate ABC transporter ATP-binding protein 2218143 tupC 7767983 tupC Clostridium botulinum A2 str. Kyoto tungstate ABC transporter ATP-binding protein YP_002804333.1 2217451 R 536232 CDS YP_002804334.1 226949243 7765076 complement(2218140..2218811) 1 NC_012563.1 identified by match to protein family HMM PF00528; tungstate ABC transporter permease 2218811 tupB 7765076 tupB Clostridium botulinum A2 str. Kyoto tungstate ABC transporter permease YP_002804334.1 2218140 R 536232 CDS YP_002804335.1 226949244 7768120 complement(2218820..2219671) 1 NC_012563.1 identified by match to protein family HMM PF01547; tungstate ABC transporter tungstate-binding protein 2219671 7768120 CLM_2163 Clostridium botulinum A2 str. Kyoto tungstate ABC transporter tungstate-binding protein YP_002804335.1 2218820 R 536232 CDS YP_002804336.1 226949245 7766498 complement(2219890..2221212) 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; MATE efflux family protein 2221212 7766498 CLM_2164 Clostridium botulinum A2 str. Kyoto MATE efflux family protein YP_002804336.1 2219890 R 536232 CDS YP_002804337.1 226949246 7765350 complement(2221212..2221409) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2221409 7765350 CLM_2165 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804337.1 2221212 R 536232 CDS YP_002804338.1 226949247 7767400 complement(2221650..2222294) 1 NC_012563.1 identified by match to protein family HMM PF09335; hypothetical protein 2222294 7767400 CLM_2166 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804338.1 2221650 R 536232 CDS YP_002804339.1 226949248 7765976 complement(2222616..2223287) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2223287 7765976 CLM_2167 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002804339.1 2222616 R 536232 CDS YP_002804340.1 226949249 7765634 complement(2223302..2224765) 1 NC_012563.1 identified by match to protein family HMM PF02687; ABC transporter permease 2224765 7765634 CLM_2168 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002804340.1 2223302 R 536232 CDS YP_002804341.1 226949250 7764267 2225101..2225259 1 NC_012563.1 hypothetical protein 2225259 7764267 CLM_2169 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804341.1 2225101 D 536232 CDS YP_002804342.1 226949251 7767771 complement(2225564..2227321) 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; putative ABC transporter ATP-binding/permease 2227321 7767771 CLM_2170 Clostridium botulinum A2 str. Kyoto putative ABC transporter ATP-binding/permease YP_002804342.1 2225564 R 536232 CDS YP_002804343.1 226949252 7766438 complement(2227318..2229048) 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 2229048 7766438 CLM_2171 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein/permease YP_002804343.1 2227318 R 536232 CDS YP_002804344.1 226949253 7766007 2229163..2229984 1 NC_012563.1 identified by match to protein family HMM PF00376; ABC transporter MerR family transcriptional regulator 2229984 7766007 CLM_2172 Clostridium botulinum A2 str. Kyoto ABC transporter MerR family transcriptional regulator YP_002804344.1 2229163 D 536232 CDS YP_002804345.1 226949254 7765171 2230403..2231029 1 NC_012563.1 identified by match to protein family HMM PF03358; flavin reductase 2231029 7765171 CLM_2173 Clostridium botulinum A2 str. Kyoto flavin reductase YP_002804345.1 2230403 D 536232 CDS YP_002804346.1 226949255 7766347 complement(2231656..2231910) 1 NC_012563.1 Hep_Hag repeat-containing protein 2231910 7766347 CLM_2174 Clostridium botulinum A2 str. Kyoto Hep_Hag repeat-containing protein YP_002804346.1 2231656 R 536232 CDS YP_002804347.1 226949256 7766867 2232541..2233539 1 NC_012563.1 identified by match to protein family HMM PF00560; putative internalin 2233539 7766867 CLM_2175 Clostridium botulinum A2 str. Kyoto putative internalin YP_002804347.1 2232541 D 536232 CDS YP_002804348.1 226949257 7766612 2233561..2235609 1 NC_012563.1 identified by match to protein family HMM PF02839; match to protein family HMM TIGR03296; carbohydrate binding protein 2235609 7766612 CLM_2176 Clostridium botulinum A2 str. Kyoto carbohydrate binding protein YP_002804348.1 2233561 D 536232 CDS YP_002804349.1 226949258 7767543 complement(2235771..2237861) 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF07728; sigma-54 dependent transcriptional regulator 2237861 7767543 CLM_2177 Clostridium botulinum A2 str. Kyoto sigma-54 dependent transcriptional regulator YP_002804349.1 2235771 R 536232 CDS YP_002804350.1 226949259 7764470 complement(2238230..2238478) 1 NC_012563.1 hypothetical protein 2238478 7764470 CLM_2178 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804350.1 2238230 R 536232 CDS YP_002804351.1 226949260 7765311 complement(2238491..2238859) 1 NC_012563.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; putative endoribonuclease L-PSP 2238859 7765311 CLM_2179 Clostridium botulinum A2 str. Kyoto putative endoribonuclease L-PSP YP_002804351.1 2238491 R 536232 CDS YP_002804352.1 226949261 7766212 complement(2238901..2240196) 1 NC_012563.1 identified by match to protein family HMM PF00375; sodium:dicarboxylate symporter family protein 2240196 7766212 CLM_2180 Clostridium botulinum A2 str. Kyoto sodium:dicarboxylate symporter family protein YP_002804352.1 2238901 R 536232 CDS YP_002804353.1 226949262 7768012 complement(2240218..2241387) 1 NC_012563.1 identified by match to protein family HMM PF00155; class I/II aminotransferase 2241387 7768012 CLM_2181 Clostridium botulinum A2 str. Kyoto class I/II aminotransferase YP_002804353.1 2240218 R 536232 CDS YP_002804354.1 226949263 7767938 2241701..2242990 1 NC_012563.1 identified by match to protein family HMM PF06354; hypothetical protein 2242990 7767938 CLM_2182 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804354.1 2241701 D 536232 CDS YP_002804355.1 226949264 7764870 2243333..2244331 1 NC_012563.1 identified by match to protein family HMM PF00560; putative internalin 2244331 7764870 CLM_2183 Clostridium botulinum A2 str. Kyoto putative internalin YP_002804355.1 2243333 D 536232 CDS YP_002804356.1 226949265 7767654 2244352..2246571 1 NC_012563.1 identified by match to protein family HMM TIGR03296; hypothetical protein 2246571 7767654 CLM_2184 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804356.1 2244352 D 536232 CDS YP_002804357.1 226949266 7764591 complement(2246772..2248211) 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 2248211 7764591 CLM_2185 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002804357.1 2246772 R 536232 CDS YP_002804358.1 226949267 7767166 complement(2248201..2248866) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 2248866 7767166 CLM_2186 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002804358.1 2248201 R 536232 CDS YP_002804359.1 226949268 7767915 complement(2249310..2250125) 1 NC_012563.1 identified by match to protein family HMM PF02596; hypothetical protein 2250125 7767915 CLM_2187 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804359.1 2249310 R 536232 CDS YP_002804360.1 226949269 7767070 complement(2250151..2250906) 1 NC_012563.1 identified by match to protein family HMM PF02361; putative ABC transporter permease 2250906 7767070 CLM_2188 Clostridium botulinum A2 str. Kyoto putative ABC transporter permease YP_002804360.1 2250151 R 536232 CDS YP_002804361.1 226949270 7765698 complement(2250922..2252355) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2252355 7765698 CLM_2189 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002804361.1 2250922 R 536232 CDS YP_002804362.1 226949271 7764878 complement(2252358..2252924) 1 NC_012563.1 putative ABC transporter permease 2252924 7764878 CLM_2190 Clostridium botulinum A2 str. Kyoto putative ABC transporter permease YP_002804362.1 2252358 R 536232 CDS YP_002804363.1 226949272 7767487 complement(2253085..2254152) 1 NC_012563.1 identified by match to protein family HMM PF01168; alanine racemase, N-terminal domain-containing protein 2254152 7767487 CLM_2191 Clostridium botulinum A2 str. Kyoto alanine racemase, N-terminal domain-containing protein YP_002804363.1 2253085 R 536232 CDS YP_002804364.1 226949273 7766609 2254541..2255626 1 NC_012563.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912; spore germination protein 2255626 7766609 CLM_2192 Clostridium botulinum A2 str. Kyoto spore germination protein YP_002804364.1 2254541 D 536232 CDS YP_002804365.1 226949274 7767432 2255709..2257211 1 NC_012563.1 identified by match to protein family HMM PF03323; spore germination protein GerA 2257211 7767432 CLM_2193 Clostridium botulinum A2 str. Kyoto spore germination protein GerA YP_002804365.1 2255709 D 536232 CDS YP_002804366.1 226949275 7767065 2257201..2258289 1 NC_012563.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912; spore germination protein 2258289 7767065 CLM_2194 Clostridium botulinum A2 str. Kyoto spore germination protein YP_002804366.1 2257201 D 536232 CDS YP_002804367.1 226949276 7766489 2258279..2259391 1 NC_012563.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887; germination protein, Ger(x)C family 2259391 7766489 CLM_2195 Clostridium botulinum A2 str. Kyoto germination protein, Ger(x)C family YP_002804367.1 2258279 D 536232 CDS YP_002804368.1 226949277 7766997 2259433..2260542 1 NC_012563.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912; spore germination protein 2260542 7766997 CLM_2196 Clostridium botulinum A2 str. Kyoto spore germination protein YP_002804368.1 2259433 D 536232 CDS YP_002804369.1 226949278 7765578 complement(2260570..2260998) 1 NC_012563.1 identified by match to protein family HMM PF09719; match to protein family HMM TIGR01909; hypothetical protein 2260998 7765578 CLM_2197 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804369.1 2260570 R 536232 CDS YP_002804370.1 226949279 7764615 2261293..2261625 1 NC_012563.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778; 4-carboxymuconolactone decarboxylase 2261625 pcaC 7764615 pcaC Clostridium botulinum A2 str. Kyoto 4-carboxymuconolactone decarboxylase YP_002804370.1 2261293 D 536232 CDS YP_002804371.1 226949280 7767180 2261638..2262618 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 2262618 7767180 CLM_2199 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002804371.1 2261638 D 536232 CDS YP_002804372.1 226949281 7766335 2262799..2263554 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein 2263554 7766335 CLM_2200 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804372.1 2262799 D 536232 CDS YP_002804373.1 226949282 7765203 complement(2263772..2265202) 1 NC_012563.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 2265202 7765203 CLM_2201 Clostridium botulinum A2 str. Kyoto potassium/proton antiporter YP_002804373.1 2263772 R 536232 CDS YP_002804374.1 226949283 7767965 complement(2265800..2267680) 1 NC_012563.1 molecular chaperone; heat shock protein 90 2267680 hsp90 7767965 hsp90 Clostridium botulinum A2 str. Kyoto heat shock protein 90 YP_002804374.1 2265800 R 536232 CDS YP_002804375.1 226949284 7767464 2268218..2269783 1 NC_012563.1 identified by match to protein family HMM PF00488; MutS domain-containing protein 2269783 7767464 CLM_2203 Clostridium botulinum A2 str. Kyoto MutS domain-containing protein YP_002804375.1 2268218 D 536232 CDS YP_002804376.1 226949285 7767104 2270265..2271692 1 NC_012563.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01992; PTS system trehalose-specific transporter subunit IIBC 2271692 treP 7767104 treP Clostridium botulinum A2 str. Kyoto PTS system trehalose-specific transporter subunit IIBC YP_002804376.1 2270265 D 536232 CDS YP_002804377.1 226949286 7767334 2271774..2273441 1 NC_012563.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403; alpha,alpha-phosphotrehalase 2273441 treC 7767334 treC Clostridium botulinum A2 str. Kyoto alpha,alpha-phosphotrehalase YP_002804377.1 2271774 D 536232 CDS YP_002804378.1 226949287 7764201 2273474..2274184 1 NC_012563.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404; trehalose operon repressor 2274184 treR 7764201 treR Clostridium botulinum A2 str. Kyoto trehalose operon repressor YP_002804378.1 2273474 D 536232 CDS YP_002804379.1 226949288 7765644 complement(2274546..2274986) 1 NC_012563.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR00848; PTS system fructose family transporter subunit IIA 2274986 7765644 CLM_2207 Clostridium botulinum A2 str. Kyoto PTS system fructose family transporter subunit IIA YP_002804379.1 2274546 R 536232 CDS YP_002804380.1 226949289 7766253 complement(2275259..2276656) 1 NC_012563.1 identified by match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR01427; PTS system fructose family transporter subunit IIBC 2276656 7766253 CLM_2208 Clostridium botulinum A2 str. Kyoto PTS system fructose family transporter subunit IIBC YP_002804380.1 2275259 R 536232 CDS YP_002804381.1 226949290 7766897 complement(2276657..2277580) 1 NC_012563.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; 1-phosphofructokinase 2277580 pfkB 7766897 pfkB Clostridium botulinum A2 str. Kyoto 1-phosphofructokinase YP_002804381.1 2276657 R 536232 CDS YP_002804382.1 226949291 7764543 complement(2277600..2278460) 1 NC_012563.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 2278460 gatY 7764543 gatY Clostridium botulinum A2 str. Kyoto tagatose-bisphosphate aldolase YP_002804382.1 2277600 R 536232 CDS YP_002804383.1 226949292 7764973 complement(2278660..2279397) 1 NC_012563.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; putative transcriptional regulator 2279397 7764973 CLM_2211 Clostridium botulinum A2 str. Kyoto putative transcriptional regulator YP_002804383.1 2278660 R 536232 CDS YP_002804384.1 226949293 7766087 complement(2279479..2279886) 1 NC_012563.1 identified by similarity to GB:AAO35217.1; hypothetical protein 2279886 7766087 CLM_2212 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804384.1 2279479 R 536232 CDS YP_002804385.1 226949294 7766242 2280248..2280643 1 NC_012563.1 identified by match to protein family HMM PF01042; endoribonuclease L-PSP family protein 2280643 7766242 CLM_2213 Clostridium botulinum A2 str. Kyoto endoribonuclease L-PSP family protein YP_002804385.1 2280248 D 536232 CDS YP_002804386.1 226949295 7765087 complement(2280983..2281852) 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 2281852 7765087 CLM_2214 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002804386.1 2280983 R 536232 CDS YP_002804387.1 226949296 7767814 2282265..2283356 1 NC_012563.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 2283356 gldA 7767814 gldA Clostridium botulinum A2 str. Kyoto glycerol dehydrogenase YP_002804387.1 2282265 D 536232 CDS YP_002804388.1 226949297 7766694 complement(2283604..2283717) 1 NC_012563.1 hypothetical protein 2283717 7766694 CLM_2216 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804388.1 2283604 R 536232 CDS YP_002804389.1 226949298 7765615 complement(2283848..2285497) 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis protein 2285497 7765615 CLM_2217 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002804389.1 2283848 R 536232 CDS YP_002804390.1 226949299 7764525 complement(2285491..2285604) 1 NC_012563.1 hypothetical protein 2285604 7764525 CLM_2218 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804390.1 2285491 R 536232 CDS YP_002804391.1 226949300 7767350 complement(2285682..2286743) 1 NC_012563.1 identified by match to protein family HMM PF01168; alanine racemase, N-terminal domain-containing protein 2286743 7767350 CLM_2219 Clostridium botulinum A2 str. Kyoto alanine racemase, N-terminal domain-containing protein YP_002804391.1 2285682 R 536232 CDS YP_002804392.1 226949301 7766270 complement(2287100..2287378) 1 NC_012563.1 hypothetical protein 2287378 7766270 CLM_2220 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804392.1 2287100 R 536232 CDS YP_002804393.1 226949302 7766993 2287848..2288912 1 NC_012563.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase family protein 2288912 7766993 CLM_2221 Clostridium botulinum A2 str. Kyoto oxidoreductase family protein YP_002804393.1 2287848 D 536232 CDS YP_002804394.1 226949303 7765364 complement(2289034..2289579) 1 NC_012563.1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis; adenine phosphoribosyltransferase 2289579 7765364 CLM_2222 Clostridium botulinum A2 str. Kyoto adenine phosphoribosyltransferase YP_002804394.1 2289034 R 536232 CDS YP_002804395.1 226949304 7764853 complement(2289595..2290659) 1 NC_012563.1 identified by match to protein family HMM PF00860; xanthine/uracil permease family protein 2290659 7764853 CLM_2223 Clostridium botulinum A2 str. Kyoto xanthine/uracil permease family protein YP_002804395.1 2289595 R 536232 CDS YP_002804396.1 226949305 7768094 complement(2291102..2291650) 1 NC_012563.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; GGDEF domain-containing protein 2291650 7768094 CLM_2225 Clostridium botulinum A2 str. Kyoto GGDEF domain-containing protein YP_002804396.1 2291102 R 536232 CDS YP_002804397.1 226949306 7765023 complement(2291884..2293188) 1 NC_012563.1 identified by match to protein family HMM PF06354; hypothetical protein 2293188 7765023 CLM_2226 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804397.1 2291884 R 536232 CDS YP_002804398.1 226949307 7765838 complement(2293448..2295223) 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF07728; putative sigma-54 dependent transcriptional regulator 2295223 7765838 CLM_2227 Clostridium botulinum A2 str. Kyoto putative sigma-54 dependent transcriptional regulator YP_002804398.1 2293448 R 536232 CDS YP_002804399.1 226949308 7766842 2295689..2296819 1 NC_012563.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD/DEAH box family ATP-dependent RNA helicase 2296819 7766842 CLM_2228 Clostridium botulinum A2 str. Kyoto DEAD/DEAH box family ATP-dependent RNA helicase YP_002804399.1 2295689 D 536232 CDS YP_002804400.1 226949309 7767673 2297139..2297936 1 NC_012563.1 identified by match to protein family HMM PF00188; match to protein family HMM TIGR02909; SCP-like extracellular protein 2297936 7767673 CLM_2229 Clostridium botulinum A2 str. Kyoto SCP-like extracellular protein YP_002804400.1 2297139 D 536232 CDS YP_002804401.1 226949310 7765572 complement(2298039..2299385) 1 NC_012563.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 2299385 7765572 CLM_2230 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002804401.1 2298039 R 536232 CDS YP_002804402.1 226949311 7766406 2299534..2300442 1 NC_012563.1 identified by match to protein family HMM PF00892; hypothetical protein 2300442 7766406 CLM_2231 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804402.1 2299534 D 536232 CDS YP_002804403.1 226949312 7766401 complement(2300741..2301892) 1 NC_012563.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 2301892 aspB 7766401 aspB Clostridium botulinum A2 str. Kyoto aspartate aminotransferase YP_002804403.1 2300741 R 536232 CDS YP_002804404.1 226949313 7765416 complement(2301912..2302634) 1 NC_012563.1 identified by match to protein family HMM PF00005; polar amino acid uptake family ABC transporter ATP-binding protein 2302634 7765416 CLM_2233 Clostridium botulinum A2 str. Kyoto polar amino acid uptake family ABC transporter ATP-binding protein YP_002804404.1 2301912 R 536232 CDS YP_002804405.1 226949314 7767575 complement(2303454..2304272) 1 NC_012563.1 identified by match to protein family HMM PF00497; polar amino acid uptake ABC transporter amino acid-binding protein 2304272 7767575 CLM_2235 Clostridium botulinum A2 str. Kyoto polar amino acid uptake ABC transporter amino acid-binding protein YP_002804405.1 2303454 R 536232 CDS YP_002804406.1 226949315 7767033 complement(2304359..2305639) 1 NC_012563.1 hypothetical protein 2305639 7767033 CLM_2236 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804406.1 2304359 R 536232 CDS YP_002804407.1 226949316 7765264 complement(2306001..2307140) 1 NC_012563.1 identified by match to protein family HMM PF00266; class V aminotransferase 2307140 7765264 CLM_2237 Clostridium botulinum A2 str. Kyoto class V aminotransferase YP_002804407.1 2306001 R 536232 CDS YP_002804408.1 226949317 7767390 complement(2307253..2307918) 1 NC_012563.1 identified by match to protein family HMM PF00302; chloramphenicol acetyltransferase 2307918 catB 7767390 catB Clostridium botulinum A2 str. Kyoto chloramphenicol acetyltransferase YP_002804408.1 2307253 R 536232 CDS YP_002804409.1 226949318 7765988 complement(2308413..2308625) 1 NC_012563.1 hypothetical protein 2308625 7765988 CLM_2239 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804409.1 2308413 R 536232 CDS YP_002804410.1 226949319 7765638 complement(2308921..2309142) 1 NC_012563.1 hypothetical protein 2309142 7765638 CLM_2240 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804410.1 2308921 R 536232 CDS YP_002804411.1 226949320 7764253 complement(2309280..2309528) 1 NC_012563.1 identified by similarity to GB:CAG19110.1; hypothetical protein 2309528 7764253 CLM_2241 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804411.1 2309280 R 536232 CDS YP_002804412.1 226949321 7767766 complement(2309716..2310432) 1 NC_012563.1 hypothetical protein 2310432 7767766 CLM_2242 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804412.1 2309716 R 536232 CDS YP_002804413.1 226949322 7766429 complement(2310842..2312197) 1 NC_012563.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter 2312197 7766429 CLM_2243 Clostridium botulinum A2 str. Kyoto amino acid/peptide transporter YP_002804413.1 2310842 R 536232 CDS YP_002804414.1 226949323 7766012 complement(2312537..2313883) 1 NC_012563.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter 2313883 7766012 CLM_2244 Clostridium botulinum A2 str. Kyoto amino acid/peptide transporter YP_002804414.1 2312537 R 536232 CDS YP_002804415.1 226949324 7766257 2314392..2315480 1 NC_012563.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Xaa-Pro dipeptidase 2315480 pepQ 7766257 pepQ Clostridium botulinum A2 str. Kyoto Xaa-Pro dipeptidase YP_002804415.1 2314392 D 536232 CDS YP_002804416.1 226949325 7767736 2315562..2316443 1 NC_012563.1 identified by match to protein family HMM PF00561; match to protein family HMM TIGR01250; prolyl aminopeptidase 2316443 pepIP 7767736 pepIP Clostridium botulinum A2 str. Kyoto prolyl aminopeptidase YP_002804416.1 2315562 D 536232 CDS YP_002804417.1 226949326 7764913 complement(2316591..2316716) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2316716 7764913 CLM_2247 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804417.1 2316591 R 536232 CDS YP_002804418.1 226949327 7768111 complement(2316733..2318226) 1 NC_012563.1 identified by match to protein family HMM PF00209; sodium:neurotransmitter symporter family protein 2318226 7768111 CLM_2248 Clostridium botulinum A2 str. Kyoto sodium:neurotransmitter symporter family protein YP_002804418.1 2316733 R 536232 CDS YP_002804419.1 226949328 7764316 complement(2318636..2320030) 1 NC_012563.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 2320030 7764316 CLM_2249 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002804419.1 2318636 R 536232 CDS YP_002804420.1 226949329 7765865 2320148..2320927 1 NC_012563.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654; phenazine biosynthesis protein 2320927 7765865 CLM_2250 Clostridium botulinum A2 str. Kyoto phenazine biosynthesis protein YP_002804420.1 2320148 D 536232 CDS YP_002804421.1 226949330 7766924 2320947..2321414 1 NC_012563.1 identified by match to protein family HMM PF01042; endoribonuclease family protein 2321414 7766924 CLM_2251 Clostridium botulinum A2 str. Kyoto endoribonuclease family protein YP_002804421.1 2320947 D 536232 CDS YP_002804422.1 226949331 7766754 complement(2321551..2322198) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2322198 7766754 CLM_2252 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804422.1 2321551 R 536232 CDS YP_002804423.1 226949332 7767861 complement(2322431..2324908) 1 NC_012563.1 thrombospondin type 3 repeat-containing protein 2324908 7767861 CLM_2253 Clostridium botulinum A2 str. Kyoto thrombospondin type 3 repeat-containing protein YP_002804423.1 2322431 R 536232 CDS YP_002804424.1 226949333 7765625 complement(2325309..2327252) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2327252 7765625 CLM_2254 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804424.1 2325309 R 536232 CDS YP_002804425.1 226949334 7766825 complement(2327267..2328502) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2328502 7766825 CLM_2255 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804425.1 2327267 R 536232 CDS YP_002804426.1 226949335 7765921 complement(2328499..2330610) 1 NC_012563.1 hypothetical protein 2330610 7765921 CLM_2256 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804426.1 2328499 R 536232 CDS YP_002804427.1 226949336 7765074 complement(2330732..2332525) 1 NC_012563.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 2332525 7765074 CLM_2257 Clostridium botulinum A2 str. Kyoto myosin-cross-reactive antigen YP_002804427.1 2330732 R 536232 CDS YP_002804428.1 226949337 7765079 complement(2332829..2333398) 1 NC_012563.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2333398 7765079 CLM_2258 Clostridium botulinum A2 str. Kyoto TetR family transcriptional regulator YP_002804428.1 2332829 R 536232 CDS YP_002804429.1 226949338 7765318 complement(2334072..2334257) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 2334257 7765318 CLM_2261 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804429.1 2334072 R 536232 CDS YP_002804430.1 226949339 7766179 2334384..2334608 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; methyl-accepting chemotaxis protein 2334608 7766179 CLM_2262 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002804430.1 2334384 D 536232 CDS YP_002804431.1 226949340 7765412 2334617..2334772 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; methyl-accepting chemotaxis protein 2334772 7765412 CLM_2263 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002804431.1 2334617 D 536232 CDS YP_002804432.1 226949341 7764661 complement(2334814..2335029) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2335029 7764661 CLM_2264 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804432.1 2334814 R 536232 CDS YP_002804433.1 226949342 7765653 complement(2335372..2336091) 1 NC_012563.1 hypothetical protein 2336091 7765653 CLM_2265 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804433.1 2335372 R 536232 CDS YP_002804434.1 226949343 7764523 2336069..2337076 1 NC_012563.1 identified by match to protein family HMM PF00535; group 2 family glycosyl transferase 2337076 7764523 CLM_2266 Clostridium botulinum A2 str. Kyoto group 2 family glycosyl transferase YP_002804434.1 2336069 D 536232 CDS YP_002804435.1 226949344 7767364 complement(2337536..2338597) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2338597 7767364 CLM_2267 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804435.1 2337536 R 536232 CDS YP_002804436.1 226949345 7765265 complement(2338641..2339285) 1 NC_012563.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR03570; transferase hexapeptide domain-containing protein 2339285 7765265 CLM_2268 Clostridium botulinum A2 str. Kyoto transferase hexapeptide domain-containing protein YP_002804436.1 2338641 R 536232 CDS YP_002804437.1 226949346 7765144 complement(2339377..2340516) 1 NC_012563.1 identified by match to protein family HMM PF01041; DegT/DnrJ/EryC1/StrS family aminotransferase 2340516 7765144 CLM_2269 Clostridium botulinum A2 str. Kyoto DegT/DnrJ/EryC1/StrS family aminotransferase YP_002804437.1 2339377 R 536232 CDS YP_002804438.1 226949347 7768003 complement(2340562..2341461) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2341461 7768003 CLM_2270 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804438.1 2340562 R 536232 CDS YP_002804439.1 226949348 7766898 2341663..2342724 1 NC_012563.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01208; glucose-1-phosphate thymidylyltransferase 2342724 7766898 CLM_2271 Clostridium botulinum A2 str. Kyoto glucose-1-phosphate thymidylyltransferase YP_002804439.1 2341663 D 536232 CDS YP_002804440.1 226949349 7767240 2342766..2343746 1 NC_012563.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 2343746 rfbB 7767240 rfbB Clostridium botulinum A2 str. Kyoto dTDP-glucose 4,6-dehydratase YP_002804440.1 2342766 D 536232 CDS YP_002804441.1 226949350 7766652 2343789..2343977 1 NC_012563.1 hypothetical protein 2343977 7766652 CLM_2273 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804441.1 2343789 D 536232 CDS YP_002804442.1 226949351 7765526 2344022..2344315 1 NC_012563.1 hypothetical protein 2344315 7765526 CLM_2274 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804442.1 2344022 D 536232 CDS YP_002804443.1 226949352 7767408 2344566..2344859 1 NC_012563.1 hypothetical protein 2344859 7767408 CLM_2275 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804443.1 2344566 D 536232 CDS YP_002804444.1 226949353 7764371 complement(2345282..2345419) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative; hypothetical protein 2345419 7764371 CLM_2276 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804444.1 2345282 R 536232 CDS YP_002804445.1 226949354 7765398 complement(2345894..2347183) 1 NC_012563.1 triacylglycerol lipase 2347183 7765398 CLM_2277 Clostridium botulinum A2 str. Kyoto triacylglycerol lipase YP_002804445.1 2345894 R 536232 CDS YP_002804446.1 226949355 7766644 complement(2348044..2348718) 1 NC_012563.1 identified by match to protein family HMM PF04892; vanZF protein 2348718 7766644 CLM_2278 Clostridium botulinum A2 str. Kyoto vanZF protein YP_002804446.1 2348044 R 536232 CDS YP_002804447.1 226949356 7767416 complement(2348859..2350040) 1 NC_012563.1 identified by match to protein family HMM PF00201; match to protein family HMM PF04101; match to protein family HMM TIGR01426; macrolide glycosyltransferase 2350040 7767416 CLM_2279 Clostridium botulinum A2 str. Kyoto macrolide glycosyltransferase YP_002804447.1 2348859 R 536232 CDS YP_002804448.1 226949357 7764389 complement(2350033..2350338) 1 NC_012563.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439; AbrB family transcriptional regulator 2350338 7764389 CLM_2280 Clostridium botulinum A2 str. Kyoto AbrB family transcriptional regulator YP_002804448.1 2350033 R 536232 CDS YP_002804449.1 226949358 7765645 complement(2350587..2351384) 1 NC_012563.1 hypothetical protein 2351384 7765645 CLM_2281 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804449.1 2350587 R 536232 CDS YP_002804450.1 226949359 7766942 complement(2351869..2351991) 1 NC_012563.1 hypothetical protein 2351991 7766942 CLM_2282 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804450.1 2351869 R 536232 CDS YP_002804451.1 226949360 7766341 complement(2352192..2353196) 1 NC_012563.1 hypothetical protein 2353196 7766341 CLM_2283 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804451.1 2352192 R 536232 CDS YP_002804452.1 226949361 7764713 complement(2353392..2354516) 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 2354516 7764713 CLM_2284 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002804452.1 2353392 R 536232 CDS YP_002804453.1 226949362 7766565 complement(2354530..2354706) 1 NC_012563.1 hypothetical protein 2354706 7766565 CLM_2285 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804453.1 2354530 R 536232 CDS YP_002804454.1 226949363 7766866 complement(2354853..2354984) 1 NC_012563.1 hypothetical protein 2354984 7766866 CLM_2286 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804454.1 2354853 R 536232 CDS YP_002804455.1 226949364 7764529 complement(2355217..2355354) 1 NC_012563.1 resolvase domain-containing protein 2355354 7764529 CLM_2287 Clostridium botulinum A2 str. Kyoto resolvase domain-containing protein YP_002804455.1 2355217 R 536232 CDS YP_002804456.1 226949365 7764408 complement(2355634..2356191) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2356191 7764408 CLM_2288 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804456.1 2355634 R 536232 CDS YP_002804457.1 226949366 7765246 complement(2356294..2356998) 1 NC_012563.1 identified by match to protein family HMM PF01520; match to protein family HMM PF05036; N-acetylmuramoyl-L-alanine amidase 2356998 7765246 CLM_2289 Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase YP_002804457.1 2356294 R 536232 CDS YP_002804458.1 226949367 7765746 complement(2356991..2357335) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF05105; match to protein family HMM TIGR01593; toxin secretion/phage lysis holin 2357335 7765746 CLM_2290 Clostridium botulinum A2 str. Kyoto toxin secretion/phage lysis holin YP_002804458.1 2356991 R 536232 CDS YP_002804459.1 226949368 7767139 complement(2357428..2357928) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2357928 7767139 CLM_2291 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804459.1 2357428 R 536232 CDS YP_002804460.1 226949369 7767455 complement(2357936..2358154) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2358154 7767455 CLM_2292 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804460.1 2357936 R 536232 CDS YP_002804461.1 226949370 7764809 complement(2358177..2358398) 1 NC_012563.1 hypothetical protein 2358398 7764809 CLM_2293 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804461.1 2358177 R 536232 CDS YP_002804462.1 226949371 7765206 complement(2358474..2361482) 1 NC_012563.1 identified by match to protein family HMM PF04313; match to protein family HMM PF04851; type III restriction protein res subunit 2361482 7765206 CLM_2294 Clostridium botulinum A2 str. Kyoto type III restriction protein res subunit YP_002804462.1 2358474 R 536232 CDS YP_002804463.1 226949372 7767264 complement(2361485..2362837) 1 NC_012563.1 restriction modification system DNA specificity domain-containing protein 2362837 7767264 CLM_2295 Clostridium botulinum A2 str. Kyoto restriction modification system DNA specificity domain-containing protein YP_002804463.1 2361485 R 536232 CDS YP_002804464.1 226949373 7764406 complement(2362830..2364545) 1 NC_012563.1 identified by match to protein family HMM PF02384; N-6 DNA methylase 2364545 7764406 CLM_2296 Clostridium botulinum A2 str. Kyoto N-6 DNA methylase YP_002804464.1 2362830 R 536232 CDS YP_002804465.1 226949374 7765462 complement(2364732..2364863) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2364863 7765462 CLM_2297 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804465.1 2364732 R 536232 CDS YP_002804466.1 226949375 7766488 complement(2365836..2368376) 1 NC_012563.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD/DEAH box helicase domain-containing protein 2368376 7766488 CLM_2298 Clostridium botulinum A2 str. Kyoto DEAD/DEAH box helicase domain-containing protein YP_002804466.1 2365836 R 536232 CDS YP_002804467.1 226949376 7767835 complement(2368394..2369296) 1 NC_012563.1 hypothetical protein 2369296 7767835 CLM_2299 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804467.1 2368394 R 536232 CDS YP_002804468.1 226949377 7765018 complement(2369740..2370984) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; hypothetical protein 2370984 7765018 CLM_2300 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804468.1 2369740 R 536232 CDS YP_002804469.1 226949378 7765927 complement(2371195..2371824) 1 NC_012563.1 identified by match to protein family HMM PF00239; recombinase 2371824 7765927 CLM_2301 Clostridium botulinum A2 str. Kyoto recombinase YP_002804469.1 2371195 R 536232 CDS YP_002804470.1 226949379 7767679 complement(2374676..2375599) 1 NC_012563.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; NAD-dependent epimerase/dehydratase family protein 2375599 7767679 CLM_2304 Clostridium botulinum A2 str. Kyoto NAD-dependent epimerase/dehydratase family protein YP_002804470.1 2374676 R 536232 CDS YP_002804471.1 226949380 7766522 2375895..2377244 1 NC_012563.1 identified by match to protein family HMM PF00535; group 2 family glycosyl transferase 2377244 7766522 CLM_2305 Clostridium botulinum A2 str. Kyoto group 2 family glycosyl transferase YP_002804471.1 2375895 D 536232 CDS YP_002804472.1 226949381 7766707 2377267..2379888 1 NC_012563.1 identified by match to protein family HMM PF00534; match to protein family HMM PF00535; group 2 family glycosyl transferase 2379888 7766707 CLM_2306 Clostridium botulinum A2 str. Kyoto group 2 family glycosyl transferase YP_002804472.1 2377267 D 536232 CDS YP_002804473.1 226949382 7767845 2380081..2380404 1 NC_012563.1 identified by match to protein family HMM PF03551; PadR family transcriptional regulator 2380404 7767845 CLM_2307 Clostridium botulinum A2 str. Kyoto PadR family transcriptional regulator YP_002804473.1 2380081 D 536232 CDS YP_002804474.1 226949383 7767874 2380409..2381005 1 NC_012563.1 hypothetical protein 2381005 7767874 CLM_2308 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804474.1 2380409 D 536232 CDS YP_002804475.1 226949384 7764739 complement(2381196..2382101) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF03547; transporter, AEC family 2382101 7764739 CLM_2309 Clostridium botulinum A2 str. Kyoto transporter, AEC family YP_002804475.1 2381196 R 536232 CDS YP_002804476.1 226949385 7766585 complement(2382229..2384184) 1 NC_012563.1 identified by similarity to SP:Q46306; match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03764; match to protein family HMM TIGR00231; tetracycline resistance protein TetP 2384184 tetP 7766585 tetP Clostridium botulinum A2 str. Kyoto tetracycline resistance protein TetP YP_002804476.1 2382229 R 536232 CDS YP_002804477.1 226949386 7767428 complement(2384727..2387504) 1 NC_012563.1 identified by match to protein family HMM PF02839; match to protein family HMM PF03272; viral enhancin protein 2387504 7767428 CLM_2311 Clostridium botulinum A2 str. Kyoto viral enhancin protein YP_002804477.1 2384727 R 536232 CDS YP_002804478.1 226949387 7765440 complement(2387946..2389817) 1 NC_012563.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525; cadmium-exporting ATPase 2389817 cadA 7765440 cadA Clostridium botulinum A2 str. Kyoto cadmium-exporting ATPase YP_002804478.1 2387946 R 536232 CDS YP_002804479.1 226949388 7764612 complement(2389999..2390274) 1 NC_012563.1 identified by match to protein family HMM PF02583; hypothetical protein 2390274 7764612 CLM_2313 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804479.1 2389999 R 536232 CDS YP_002804480.1 226949389 7764732 complement(2390397..2390687) 1 NC_012563.1 identified by match to protein family HMM PF00936; microcompartments family protein 2390687 7764732 CLM_2314 Clostridium botulinum A2 str. Kyoto microcompartments family protein YP_002804480.1 2390397 R 536232 CDS YP_002804481.1 226949390 7764459 complement(2390761..2391411) 1 NC_012563.1 identified by match to protein family HMM PF06130; propanediol utilization protein PduL-like protein 2391411 7764459 CLM_2315 Clostridium botulinum A2 str. Kyoto propanediol utilization protein PduL-like protein YP_002804481.1 2390761 R 536232 CDS YP_002804482.1 226949391 7767003 complement(2391411..2393009) 1 NC_012563.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR02518; acetaldehyde dehydrogenase 2393009 eutE 7767003 eutE Clostridium botulinum A2 str. Kyoto acetaldehyde dehydrogenase YP_002804482.1 2391411 R 536232 CDS YP_002804483.1 226949392 7766231 complement(2393044..2393841) 1 NC_012563.1 identified by match to protein family HMM PF00936; microcompartments family protein 2393841 7766231 CLM_2317 Clostridium botulinum A2 str. Kyoto microcompartments family protein YP_002804483.1 2393044 R 536232 CDS YP_002804484.1 226949393 7765767 complement(2393862..2394524) 1 NC_012563.1 identified by match to protein family HMM PF05899; match to protein family HMM PF06249; ethanolamine utilization protein EutQ-like protein 2394524 7765767 CLM_2318 Clostridium botulinum A2 str. Kyoto ethanolamine utilization protein EutQ-like protein YP_002804484.1 2393862 R 536232 CDS YP_002804485.1 226949394 7764641 complement(2394723..2394986) 1 NC_012563.1 identified by match to protein family HMM PF03319; putative polyhedral organelle formation protein 2394986 7764641 CLM_2319 Clostridium botulinum A2 str. Kyoto putative polyhedral organelle formation protein YP_002804485.1 2394723 R 536232 CDS YP_002804486.1 226949395 7767506 complement(2394983..2395285) 1 NC_012563.1 identified by match to protein family HMM PF00936; hypothetical protein 2395285 7767506 CLM_2320 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804486.1 2394983 R 536232 CDS YP_002804487.1 226949396 7766162 complement(2395363..2396208) 1 NC_012563.1 identified by match to protein family HMM TIGR02529; ethanolamine utilization protein EutJ family protein 2396208 7766162 CLM_2321 Clostridium botulinum A2 str. Kyoto ethanolamine utilization protein EutJ family protein YP_002804487.1 2395363 R 536232 CDS YP_002804488.1 226949397 7766190 complement(2396190..2396918) 1 NC_012563.1 hypothetical protein 2396918 7766190 CLM_2322 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804488.1 2396190 R 536232 CDS YP_002804489.1 226949398 7765143 complement(2396925..2397371) 1 NC_012563.1 GTP-binding protein, EutP/PduV family 2397371 7765143 CLM_2323 Clostridium botulinum A2 str. Kyoto GTP-binding protein, EutP/PduV family YP_002804489.1 2396925 R 536232 CDS YP_002804490.1 226949399 7767999 complement(2397368..2397721) 1 NC_012563.1 identified by match to protein family HMM PF00936; ethanolamine utilization protein EutS-like protein 2397721 7767999 CLM_2324 Clostridium botulinum A2 str. Kyoto ethanolamine utilization protein EutS-like protein YP_002804490.1 2397368 R 536232 CDS YP_002804491.1 226949400 7765194 complement(2397761..2398714) 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF04055; match to protein family HMM TIGR02494; glycyl-radical enzyme activating family protein 2398714 7765194 CLM_2325 Clostridium botulinum A2 str. Kyoto glycyl-radical enzyme activating family protein YP_002804491.1 2397761 R 536232 CDS YP_002804492.1 226949401 7766284 complement(2398878..2401418) 1 NC_012563.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; formate acetyltransferase 2401418 7766284 CLM_2326 Clostridium botulinum A2 str. Kyoto formate acetyltransferase YP_002804492.1 2398878 R 536232 CDS YP_002804493.1 226949402 7766459 complement(2401468..2402961) 1 NC_012563.1 aldehyde dehydrogenase family protein 2402961 7766459 CLM_2327 Clostridium botulinum A2 str. Kyoto aldehyde dehydrogenase family protein YP_002804493.1 2401468 R 536232 CDS YP_002804494.1 226949403 7767584 complement(2402999..2403307) 1 NC_012563.1 identified by match to protein family HMM PF00936; microcompartments family protein 2403307 7767584 CLM_2328 Clostridium botulinum A2 str. Kyoto microcompartments family protein YP_002804494.1 2402999 R 536232 CDS YP_002804495.1 226949404 7767896 complement(2403331..2403627) 1 NC_012563.1 identified by match to protein family HMM PF00936; microcompartments family protein 2403627 7767896 CLM_2329 Clostridium botulinum A2 str. Kyoto microcompartments family protein YP_002804495.1 2403331 R 536232 CDS YP_002804496.1 226949405 7765011 complement(2403940..2404206) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2404206 7765011 CLM_2330 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804496.1 2403940 R 536232 CDS YP_002804497.1 226949406 7766995 complement(2404193..2405305) 1 NC_012563.1 hypothetical protein 2405305 7766995 CLM_2331 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804497.1 2404193 R 536232 CDS YP_002804498.1 226949407 7768109 complement(2405791..2406621) 1 NC_012563.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 2406621 7768109 CLM_2332 Clostridium botulinum A2 str. Kyoto MerR family transcriptional regulator YP_002804498.1 2405791 R 536232 CDS YP_002804499.1 226949408 7764257 complement(2406725..2407867) 1 NC_012563.1 identified by match to protein family HMM PF00465; iron-containing alcohol dehydrogenase 2407867 7764257 CLM_2333 Clostridium botulinum A2 str. Kyoto iron-containing alcohol dehydrogenase YP_002804499.1 2406725 R 536232 CDS YP_002804500.1 226949409 7765340 2408390..2409703 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; MATE efflux family protein 2409703 7765340 CLM_2334 Clostridium botulinum A2 str. Kyoto MATE efflux family protein YP_002804500.1 2408390 D 536232 CDS YP_002804501.1 226949410 7765192 complement(2409800..2411044) 1 NC_012563.1 identified by match to protein family HMM PF07690; inner membrane transport protein YeaN 2411044 7765192 CLM_2335 Clostridium botulinum A2 str. Kyoto inner membrane transport protein YeaN YP_002804501.1 2409800 R 536232 CDS YP_002804502.1 226949411 7764922 complement(2411085..2411774) 1 NC_012563.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 2411774 7764922 CLM_2336 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002804502.1 2411085 R 536232 CDS YP_002804503.1 226949412 7767339 2411937..2412836 1 NC_012563.1 identified by match to protein family HMM PF00583; match to protein family HMM PF01047; MarR family transcriptional regulator 2412836 7767339 CLM_2337 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002804503.1 2411937 D 536232 CDS YP_002804504.1 226949413 7767158 complement(2413827..2414615) 1 NC_012563.1 identified by match to protein family HMM PF09234; hypothetical protein 2414615 7767158 CLM_2341 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804504.1 2413827 R 536232 CDS YP_002804505.1 226949414 7766944 complement(2415419..2415781) 1 NC_012563.1 hypothetical protein 2415781 7766944 CLM_2342 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804505.1 2415419 R 536232 CDS YP_002804506.1 226949415 7765863 complement(2415794..2416282) 1 NC_012563.1 identified by match to protein family HMM TIGR01764; DNA binding protein, excisionase family 2416282 7765863 CLM_2343 Clostridium botulinum A2 str. Kyoto DNA binding protein, excisionase family YP_002804506.1 2415794 R 536232 CDS YP_002804507.1 226949416 7764256 complement(2416561..2417199) 1 NC_012563.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase family protein 2417199 7764256 CLM_2344 Clostridium botulinum A2 str. Kyoto sortase family protein YP_002804507.1 2416561 R 536232 CDS YP_002804508.1 226949417 7767357 complement(2417168..2419897) 1 NC_012563.1 identified by match to protein family HMM TIGR01167; LPXTG-motif cell wall anchor domain-containing protein 2419897 7767357 CLM_2345 Clostridium botulinum A2 str. Kyoto LPXTG-motif cell wall anchor domain-containing protein YP_002804508.1 2417168 R 536232 CDS YP_002804509.1 226949418 7767870 complement(2420214..2421233) 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 2421233 7767870 CLM_2346 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002804509.1 2420214 R 536232 CDS YP_002804510.1 226949419 7765017 complement(2421230..2421901) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 2421901 7765017 CLM_2347 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002804510.1 2421230 R 536232 CDS YP_002804511.1 226949420 7766723 complement(2422099..2422809) 1 NC_012563.1 hypothetical protein 2422809 7766723 CLM_2348 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804511.1 2422099 R 536232 CDS YP_002804512.1 226949421 7767873 complement(2422802..2424958) 1 NC_012563.1 hypothetical protein 2424958 7767873 CLM_2349 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804512.1 2422802 R 536232 CDS YP_002804513.1 226949422 7767851 complement(2425030..2425905) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2425905 7767851 CLM_2350 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002804513.1 2425030 R 536232 CDS YP_002804514.1 226949423 7766716 complement(2425965..2427959) 1 NC_012563.1 identified by match to protein family HMM PF02687; ABC transporter permease 2427959 7766716 CLM_2351 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002804514.1 2425965 R 536232 CDS YP_002804515.1 226949424 7767305 complement(2428265..2429350) 1 NC_012563.1 FAD/NAD(P)-binding domain; putative oxidoreductase 2429350 7767305 CLM_2352 Clostridium botulinum A2 str. Kyoto putative oxidoreductase YP_002804515.1 2428265 R 536232 CDS YP_002804516.1 226949425 7764454 complement(2429343..2429588) 1 NC_012563.1 hypothetical protein 2429588 7764454 CLM_2353 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804516.1 2429343 R 536232 CDS YP_002804517.1 226949426 7764951 complement(2429604..2430095) 1 NC_012563.1 hypothetical protein 2430095 7764951 CLM_2354 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804517.1 2429604 R 536232 CDS YP_002804518.1 226949427 7766050 complement(2430547..2431587) 1 NC_012563.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase family oxidoreductase 2431587 7766050 CLM_2355 Clostridium botulinum A2 str. Kyoto zinc-binding dehydrogenase family oxidoreductase YP_002804518.1 2430547 R 536232 CDS YP_002804519.1 226949428 7764266 complement(2431654..2432511) 1 NC_012563.1 identified by match to protein family HMM PF01261; AP endonuclease 2432511 7764266 CLM_2356 Clostridium botulinum A2 str. Kyoto AP endonuclease YP_002804519.1 2431654 R 536232 CDS YP_002804520.1 226949429 7765349 complement(2432595..2433734) 1 NC_012563.1 identified by match to protein family HMM PF01761; putative 3-dehydroquinate synthase 2433734 7765349 CLM_2357 Clostridium botulinum A2 str. Kyoto putative 3-dehydroquinate synthase YP_002804520.1 2432595 R 536232 CDS YP_002804521.1 226949430 7766766 complement(2434300..2436291) 1 NC_012563.1 identified by match to protein family HMM PF02687; ABC transporter permease 2436291 7766766 CLM_2358 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002804521.1 2434300 R 536232 CDS YP_002804522.1 226949431 7767890 complement(2436281..2437048) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2437048 7767890 CLM_2359 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002804522.1 2436281 R 536232 CDS YP_002804523.1 226949432 7765060 complement(2437826..2438179) 1 NC_012563.1 hypothetical protein 2438179 7765060 CLM_2360 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804523.1 2437826 R 536232 CDS YP_002804524.1 226949433 7766189 complement(2438505..2440598) 1 NC_012563.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279; putative PRD domain-containing protein/PTS system L-ascorbate family, IIA component 2440598 7766189 CLM_2361 Clostridium botulinum A2 str. Kyoto putative PRD domain-containing protein/PTS system L-ascorbate family, IIA component YP_002804524.1 2438505 R 536232 CDS YP_002804525.1 226949434 7767372 complement(2440810..2442174) 1 NC_012563.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 2442174 ulaA 7767372 ulaA Clostridium botulinum A2 str. Kyoto PTS system ascorbate-specific transporter subunit IIC YP_002804525.1 2440810 R 536232 CDS YP_002804526.1 226949435 7764442 complement(2442187..2442471) 1 NC_012563.1 identified by match to protein family HMM PF02302; putative PTS system L-Ascorbate family, IIB component 2442471 7764442 CLM_2363 Clostridium botulinum A2 str. Kyoto putative PTS system L-Ascorbate family, IIB component YP_002804526.1 2442187 R 536232 CDS YP_002804527.1 226949436 7765530 complement(2442500..2442937) 1 NC_012563.1 identified by match to protein family HMM PF00359; putative PTS system L-ascorbate family, IIA component 2442937 7765530 CLM_2364 Clostridium botulinum A2 str. Kyoto putative PTS system L-ascorbate family, IIA component YP_002804527.1 2442500 R 536232 CDS YP_002804528.1 226949437 7766696 complement(2442961..2443677) 1 NC_012563.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; putative translaldolase 2443677 7766696 CLM_2365 Clostridium botulinum A2 str. Kyoto putative translaldolase YP_002804528.1 2442961 R 536232 CDS YP_002804529.1 226949438 7767082 complement(2443912..2444316) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2444316 7767082 CLM_2366 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804529.1 2443912 R 536232 CDS YP_002804530.1 226949439 7767937 complement(2444581..2445315) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2445315 7767937 CLM_2367 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804530.1 2444581 R 536232 CDS YP_002804531.1 226949440 7765480 complement(2445618..2445803) 1 NC_012563.1 hypothetical protein 2445803 7765480 CLM_2368 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804531.1 2445618 R 536232 CDS YP_002804532.1 226949441 7764730 complement(2445920..2446534) 1 NC_012563.1 identified by match to protein family HMM PF00132; O-acetyltransferase family protein 2446534 7764730 CLM_2369 Clostridium botulinum A2 str. Kyoto O-acetyltransferase family protein YP_002804532.1 2445920 R 536232 CDS YP_002804533.1 226949442 7766938 2447529..2448935 1 NC_012563.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter 2448935 7766938 CLM_2372 Clostridium botulinum A2 str. Kyoto amino acid/peptide transporter YP_002804533.1 2447529 D 536232 CDS YP_002804534.1 226949443 7766011 complement(2449039..2449779) 1 NC_012563.1 identified by match to protein family HMM PF08242; hypothetical protein 2449779 7766011 CLM_2373 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804534.1 2449039 R 536232 CDS YP_002804535.1 226949444 7765103 complement(2449786..2450676) 1 NC_012563.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445; AraC family transcriptional regulator 2450676 7765103 CLM_2374 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002804535.1 2449786 R 536232 CDS YP_002804536.1 226949445 7766254 2450977..2451498 1 NC_012563.1 hypothetical protein 2451498 7766254 CLM_2375 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804536.1 2450977 D 536232 CDS YP_002804537.1 226949446 7765421 complement(2451609..2453606) 1 NC_012563.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00724; match to protein family HMM PF07992; 2-enoate reductase 2453606 enr 7765421 enr Clostridium botulinum A2 str. Kyoto 2-enoate reductase YP_002804537.1 2451609 R 536232 CDS YP_002804538.1 226949447 7765263 complement(2453703..2454500) 1 NC_012563.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 2454500 7765263 CLM_2377 Clostridium botulinum A2 str. Kyoto MerR family transcriptional regulator YP_002804538.1 2453703 R 536232 CDS YP_002804539.1 226949448 7764440 complement(2454549..2454842) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2454842 7764440 CLM_2378 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804539.1 2454549 R 536232 CDS YP_002804540.1 226949449 7768093 complement(2454996..2455187) 1 NC_012563.1 hypothetical protein 2455187 7768093 CLM_2379 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804540.1 2454996 R 536232 CDS YP_002804541.1 226949450 7765850 complement(2456642..2457577) 1 NC_012563.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654; phenazine biosynthesis protein 2457577 7765850 CLM_2382 Clostridium botulinum A2 str. Kyoto phenazine biosynthesis protein YP_002804541.1 2456642 R 536232 CDS YP_002804542.1 226949451 7767728 2457902..2459395 1 NC_012563.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 2459395 7767728 CLM_2383 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002804542.1 2457902 D 536232 CDS YP_002804543.1 226949452 7764604 2460445..2460897 1 NC_012563.1 hypothetical protein 2460897 7764604 CLM_2384 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804543.1 2460445 D 536232 CDS YP_002804544.1 226949453 7766031 complement(2460979..2461425) 1 NC_012563.1 identified by match to protein family HMM PF01381; putative DNA-binding protein 2461425 7766031 CLM_2385 Clostridium botulinum A2 str. Kyoto putative DNA-binding protein YP_002804544.1 2460979 R 536232 CDS YP_002804545.1 226949454 7766872 complement(2461593..2462624) 1 NC_012563.1 identified by match to protein family HMM PF07859; putative lipase/esterase 2462624 7766872 CLM_2386 Clostridium botulinum A2 str. Kyoto putative lipase/esterase YP_002804545.1 2461593 R 536232 CDS YP_002804546.1 226949455 7765651 complement(2462890..2464242) 1 NC_012563.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; amidohydrolase family protein 2464242 7765651 CLM_2387 Clostridium botulinum A2 str. Kyoto amidohydrolase family protein YP_002804546.1 2462890 R 536232 CDS YP_002804547.1 226949456 7767780 complement(2464318..2465661) 1 NC_012563.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR03173; xanthine/uracil permease family protein 2465661 7767780 CLM_2388 Clostridium botulinum A2 str. Kyoto xanthine/uracil permease family protein YP_002804547.1 2464318 R 536232 CDS YP_002804548.1 226949457 7764841 2466099..2466998 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2466998 7764841 CLM_2390 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804548.1 2466099 D 536232 CDS YP_002804549.1 226949458 7766107 2467338..2468660 1 NC_012563.1 identified by match to protein family HMM PF00324; amino acid permease family protein 2468660 7766107 CLM_2391 Clostridium botulinum A2 str. Kyoto amino acid permease family protein YP_002804549.1 2467338 D 536232 CDS YP_002804550.1 226949459 7766287 complement(2468728..2469462) 1 NC_012563.1 protein kinase domain-containing protein 2469462 7766287 CLM_2392 Clostridium botulinum A2 str. Kyoto protein kinase domain-containing protein YP_002804550.1 2468728 R 536232 CDS YP_002804551.1 226949460 7767280 complement(2469949..2470722) 1 NC_012563.1 identified by match to protein family HMM PF01869; match to protein family HMM TIGR00241; 2-hydroxyglutaryl-CoA dehydratase subunit A 2470722 hgdC_1 7767280 hgdC_1 Clostridium botulinum A2 str. Kyoto 2-hydroxyglutaryl-CoA dehydratase subunit A YP_002804551.1 2469949 R 536232 CDS YP_002804552.1 226949461 7764678 complement(2470799..2472499) 1 NC_012563.1 hypothetical protein 2472499 7764678 CLM_2394 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804552.1 2470799 R 536232 CDS YP_002804553.1 226949462 7765541 complement(2472800..2473849) 1 NC_012563.1 identified by match to protein family HMM PF00766; match to protein family HMM PF01012; electron transfer flavoprotein subunit alpha/FixB family protein 2473849 7765541 CLM_2395 Clostridium botulinum A2 str. Kyoto electron transfer flavoprotein subunit alpha/FixB family protein YP_002804553.1 2472800 R 536232 CDS YP_002804554.1 226949463 7767934 complement(2473868..2474653) 1 NC_012563.1 identified by match to protein family HMM PF01012; electron transfer flavoprotein subunit beta/FixA family protein 2474653 7767934 CLM_2396 Clostridium botulinum A2 str. Kyoto electron transfer flavoprotein subunit beta/FixA family protein YP_002804554.1 2473868 R 536232 CDS YP_002804555.1 226949464 7764815 complement(2474690..2475823) 1 NC_012563.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase family protein 2475823 7764815 CLM_2397 Clostridium botulinum A2 str. Kyoto acyl-CoA dehydrogenase family protein YP_002804555.1 2474690 R 536232 CDS YP_002804556.1 226949465 7765185 complement(2476322..2477449) 1 NC_012563.1 identified by similarity to SP:P11570; match to protein family HMM PF06050; (R)-2-hydroxyglutaryl-CoA dehydratase subunit beta 2477449 hgdB 7765185 hgdB Clostridium botulinum A2 str. Kyoto (R)-2-hydroxyglutaryl-CoA dehydratase subunit beta YP_002804556.1 2476322 R 536232 CDS YP_002804557.1 226949466 7764365 complement(2477449..2478681) 1 NC_012563.1 identified by similarity to SP:P11569; match to protein family HMM PF06050; (R)-2-hydroxyglutaryl-CoA dehydratase subunit alpha family protein 2478681 7764365 CLM_2399 Clostridium botulinum A2 str. Kyoto (R)-2-hydroxyglutaryl-CoA dehydratase subunit alpha family protein YP_002804557.1 2477449 R 536232 CDS YP_002804558.1 226949467 7766894 complement(2478744..2479958) 1 NC_012563.1 identified by similarity to GB:AAV40822.1; match to protein family HMM PF02515; 3-methyl-2-oxobutanoate dehydrogenase 2479958 hadA 7766894 hadA Clostridium botulinum A2 str. Kyoto 3-methyl-2-oxobutanoate dehydrogenase YP_002804558.1 2478744 R 536232 CDS YP_002804559.1 226949468 7767743 complement(2480699..2481520) 1 NC_012563.1 identified by match to protein family HMM PF00037; iron-sulfur cluster-binding protein 2481520 7767743 CLM_2401 Clostridium botulinum A2 str. Kyoto iron-sulfur cluster-binding protein YP_002804559.1 2480699 R 536232 CDS YP_002804560.1 226949469 7765141 2481921..2483192 1 NC_012563.1 identified by match to protein family HMM PF06050; 2-hydroxyglutaryl-CoA dehydratase subunit D 2483192 7765141 CLM_2402 Clostridium botulinum A2 str. Kyoto 2-hydroxyglutaryl-CoA dehydratase subunit D YP_002804560.1 2481921 D 536232 CDS YP_002804561.1 226949470 7765974 2483195..2484886 1 NC_012563.1 identified by match to protein family HMM PF01869; match to protein family HMM PF06050; match to protein family HMM TIGR00241; benzoyl-CoA reductase subunit A 2484886 bcrA 7765974 bcrA Clostridium botulinum A2 str. Kyoto benzoyl-CoA reductase subunit A YP_002804561.1 2483195 D 536232 CDS YP_002804562.1 226949471 7766297 complement(2485185..2486336) 1 NC_012563.1 identified by match to protein family HMM PF00015; putative methyl-accepting chemotaxis protein 2486336 7766297 CLM_2404 Clostridium botulinum A2 str. Kyoto putative methyl-accepting chemotaxis protein YP_002804562.1 2485185 R 536232 CDS YP_002804563.1 226949472 7767267 complement(2486920..2487519) 1 NC_012563.1 hypothetical protein 2487519 7767267 CLM_2405 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804563.1 2486920 R 536232 CDS YP_002804564.1 226949473 7764580 complement(2487936..2488529) 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2488529 7764580 CLM_2406 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002804564.1 2487936 R 536232 CDS YP_002804565.1 226949474 7765545 2488878..2489291 1 NC_012563.1 identified by similarity to SP:Q8Y6I2; match to protein family HMM PF00903; fosfomycin resistance protein FosX 2489291 fosX 7765545 fosX Clostridium botulinum A2 str. Kyoto fosfomycin resistance protein FosX YP_002804565.1 2488878 D 536232 CDS YP_002804566.1 226949475 7767361 complement(2489455..2490843) 1 NC_012563.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM PF06808; match to protein family HMM TIGR00791; gluconate permease 2490843 gntP 7767361 gntP Clostridium botulinum A2 str. Kyoto gluconate permease YP_002804566.1 2489455 R 536232 CDS YP_002804567.1 226949476 7764261 complement(2491070..2492074) 1 NC_012563.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 2492074 pdxA 7764261 pdxA Clostridium botulinum A2 str. Kyoto 4-hydroxythreonine-4-phosphate dehydrogenase YP_002804567.1 2491070 R 536232 CDS YP_002804568.1 226949477 7767579 complement(2492087..2493424) 1 NC_012563.1 hypothetical protein 2493424 7767579 CLM_2410 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804568.1 2492087 R 536232 CDS YP_002804569.1 226949478 7764504 complement(2493489..2494247) 1 NC_012563.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator 2494247 7764504 CLM_2411 Clostridium botulinum A2 str. Kyoto DeoR family transcriptional regulator YP_002804569.1 2493489 R 536232 CDS YP_002804570.1 226949479 7766848 2494782..2494949 1 NC_012563.1 hypothetical protein 2494949 7766848 CLM_2412 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804570.1 2494782 D 536232 CDS YP_002804571.1 226949480 7767670 complement(2495191..2496084) 1 NC_012563.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family protein 2496084 7767670 CLM_2413 Clostridium botulinum A2 str. Kyoto CAAX amino terminal protease family protein YP_002804571.1 2495191 R 536232 CDS YP_002804572.1 226949481 7765077 2496499..2497884 1 NC_012563.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 2497884 7765077 CLM_2414 Clostridium botulinum A2 str. Kyoto ErfK/YbiS/YcfS/YnhG family protein YP_002804572.1 2496499 D 536232 CDS YP_002804573.1 226949482 7765936 complement(2498329..2498922) 1 NC_012563.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2498922 7765936 CLM_2415 Clostridium botulinum A2 str. Kyoto TetR family transcriptional regulator YP_002804573.1 2498329 R 536232 CDS YP_002804574.1 226949483 7766324 2499066..2499593 1 NC_012563.1 hypothetical protein 2499593 7766324 CLM_2416 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804574.1 2499066 D 536232 CDS YP_002804575.1 226949484 7767057 2500654..2503116 1 NC_012563.1 hypothetical protein 2503116 7767057 CLM_2419 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804575.1 2500654 D 536232 CDS YP_002804576.1 226949485 7764820 complement(2503187..2504260) 1 NC_012563.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase family oxidoreductase 2504260 7764820 CLM_2420 Clostridium botulinum A2 str. Kyoto zinc-binding dehydrogenase family oxidoreductase YP_002804576.1 2503187 R 536232 CDS YP_002804577.1 226949486 7765677 complement(2504709..2506673) 1 NC_012563.1 identified by match to protein family HMM PF03063; match to protein family HMM TIGR01702; carbon monoxide dehydrogenase 2506673 7765677 CLM_2421 Clostridium botulinum A2 str. Kyoto carbon monoxide dehydrogenase YP_002804577.1 2504709 R 536232 CDS YP_002804578.1 226949487 7767072 complement(2506860..2506979) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2506979 7767072 CLM_2422 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804578.1 2506860 R 536232 CDS YP_002804579.1 226949488 7767963 complement(2507119..2507268) 1 NC_012563.1 hypothetical protein 2507268 7767963 CLM_2423 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804579.1 2507119 R 536232 CDS YP_002804580.1 226949489 7766239 2507467..2507808 1 NC_012563.1 identified by match to protein family HMM PF01155; hydrogenase nickel insertion protein HypA 2507808 hypA 7766239 hypA Clostridium botulinum A2 str. Kyoto hydrogenase nickel insertion protein HypA YP_002804580.1 2507467 D 536232 CDS YP_002804581.1 226949490 7767460 2507811..2508449 1 NC_012563.1 identified by match to protein family HMM PF02492; match to protein family HMM TIGR00073; hydrogenase accessory protein HypB 2508449 hypB 7767460 hypB Clostridium botulinum A2 str. Kyoto hydrogenase accessory protein HypB YP_002804581.1 2507811 D 536232 CDS YP_002804582.1 226949491 7764842 complement(2508472..2508828) 1 NC_012563.1 identified by match to protein family HMM PF02579; dinitrogenase iron-molybdenum cofactor family protein 2508828 7764842 CLM_2426 Clostridium botulinum A2 str. Kyoto dinitrogenase iron-molybdenum cofactor family protein YP_002804582.1 2508472 R 536232 CDS YP_002804583.1 226949492 7765757 complement(2508924..2509769) 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01656; CobQ/CobB/MinD/ParA family protein 2509769 7765757 CLM_2427 Clostridium botulinum A2 str. Kyoto CobQ/CobB/MinD/ParA family protein YP_002804583.1 2508924 R 536232 CDS YP_002804584.1 226949493 7767520 complement(2509760..2510590) 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01656; CobQ/CobB/MinD/ParA family protein 2510590 7767520 CLM_2428 Clostridium botulinum A2 str. Kyoto CobQ/CobB/MinD/ParA family protein YP_002804584.1 2509760 R 536232 CDS YP_002804585.1 226949494 7765579 complement(2510615..2510974) 1 NC_012563.1 identified by match to protein family HMM PF02579; dinitrogenase iron-molybdenum cofactor family protein 2510974 7765579 CLM_2429 Clostridium botulinum A2 str. Kyoto dinitrogenase iron-molybdenum cofactor family protein YP_002804585.1 2510615 R 536232 CDS YP_002804586.1 226949495 7764477 complement(2511549..2511926) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2511926 7764477 CLM_2430 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804586.1 2511549 R 536232 CDS YP_002804587.1 226949496 7767895 complement(2512221..2512985) 1 NC_012563.1 identified by match to protein family HMM PF00691; chemotaxis MotB protein 2512985 motB 7767895 motB Clostridium botulinum A2 str. Kyoto chemotaxis MotB protein YP_002804587.1 2512221 R 536232 CDS YP_002804588.1 226949497 7766729 complement(2513003..2513788) 1 NC_012563.1 With Mot B forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.; flagellar motor protein MotA 2513788 motA 7766729 motA Clostridium botulinum A2 str. Kyoto flagellar motor protein MotA YP_002804588.1 2513003 R 536232 CDS YP_002804589.1 226949498 7766126 2513817..2513936 1 NC_012563.1 hypothetical protein 2513936 7766126 CLM_2433 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804589.1 2513817 D 536232 CDS YP_002804590.1 226949499 7765022 complement(2514477..2516093) 1 NC_012563.1 identified by match to protein family HMM PF04122; amidase domain-containing protein 2516093 7765022 CLM_2434 Clostridium botulinum A2 str. Kyoto amidase domain-containing protein YP_002804590.1 2514477 R 536232 CDS YP_002804591.1 226949500 7766453 complement(2516403..2517026) 1 NC_012563.1 hypothetical protein 2517026 7766453 CLM_2435 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804591.1 2516403 R 536232 CDS YP_002804592.1 226949501 7765339 complement(2517306..2517647) 1 NC_012563.1 hypothetical protein 2517647 7765339 CLM_2436 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804592.1 2517306 R 536232 CDS YP_002804593.1 226949502 7764674 complement(2517653..2519608) 1 NC_012563.1 identified by match to protein family HMM PF03169; match to protein family HMM TIGR00728; match to protein family HMM TIGR00733; oligopeptide transporter, OPT family 2519608 7764674 CLM_2437 Clostridium botulinum A2 str. Kyoto oligopeptide transporter, OPT family YP_002804593.1 2517653 R 536232 CDS YP_002804594.1 226949503 7764698 complement(2519726..2521171) 1 NC_012563.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893; aminoacyl-histidine dipeptidase 2521171 pepD 7764698 pepD Clostridium botulinum A2 str. Kyoto aminoacyl-histidine dipeptidase YP_002804594.1 2519726 R 536232 CDS YP_002804595.1 226949504 7767656 complement(2521731..2522759) 1 NC_012563.1 identified by match to protein family HMM PF01212; putative low specificity L-threonine aldolase 2522759 7767656 CLM_2439 Clostridium botulinum A2 str. Kyoto putative low specificity L-threonine aldolase YP_002804595.1 2521731 R 536232 CDS YP_002804596.1 226949505 7765516 2523467..2523601 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2523601 7765516 CLM_2441 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804596.1 2523467 D 536232 CDS YP_002804597.1 226949506 7767289 complement(2523598..2524740) 1 NC_012563.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 2524740 glxK 7767289 glxK Clostridium botulinum A2 str. Kyoto glycerate kinase YP_002804597.1 2523598 R 536232 CDS YP_002804598.1 226949507 7764415 complement(2524960..2525091) 1 NC_012563.1 hypothetical protein 2525091 7764415 CLM_2442 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804598.1 2524960 R 536232 CDS YP_002804599.1 226949508 7766863 2525379..2526176 1 NC_012563.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 2526176 7766863 CLM_2443 Clostridium botulinum A2 str. Kyoto short chain dehydrogenase/reductase family oxidoreductase YP_002804599.1 2525379 D 536232 CDS YP_002804600.1 226949509 7768004 complement(2526441..2527619) 1 NC_012563.1 putative sodium extrusion protein NatB 2527619 7768004 CLM_2444 Clostridium botulinum A2 str. Kyoto putative sodium extrusion protein NatB YP_002804600.1 2526441 R 536232 CDS YP_002804601.1 226949510 7765058 complement(2527633..2528352) 1 NC_012563.1 identified by match to protein family HMM PF00005; putative sodium extrusion ATP-binding protein NatA 2528352 7765058 CLM_2445 Clostridium botulinum A2 str. Kyoto putative sodium extrusion ATP-binding protein NatA YP_002804601.1 2527633 R 536232 CDS YP_002804602.1 226949511 7764294 complement(2528817..2529272) 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2529272 7764294 CLM_2446 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002804602.1 2528817 R 536232 CDS YP_002804603.1 226949512 7766226 complement(2529286..2529750) 1 NC_012563.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 2529750 7766226 CLM_2447 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002804603.1 2529286 R 536232 CDS YP_002804604.1 226949513 7764476 2530157..2530291 1 NC_012563.1 hypothetical protein 2530291 7764476 CLM_2448 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804604.1 2530157 D 536232 CDS YP_002804605.1 226949514 7764903 complement(2530498..2530902) 1 NC_012563.1 hypothetical protein 2530902 7764903 CLM_2449 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804605.1 2530498 R 536232 CDS YP_002804606.1 226949515 7765569 complement(2530999..2532069) 1 NC_012563.1 identified by match to protein family HMM PF01208; uroporphyrinogen decarboxylase family protein 2532069 7765569 CLM_2450 Clostridium botulinum A2 str. Kyoto uroporphyrinogen decarboxylase family protein YP_002804606.1 2530999 R 536232 CDS YP_002804607.1 226949516 7767751 complement(2532418..2533866) 1 NC_012563.1 identified by match to protein family HMM PF01266; match to protein family HMM PF04324; FAD/[2Fe-2S]-binding family oxidoreductase 2533866 7767751 CLM_2451 Clostridium botulinum A2 str. Kyoto FAD/[2Fe-2S]-binding family oxidoreductase YP_002804607.1 2532418 R 536232 CDS YP_002804608.1 226949517 7764896 2534213..2535031 1 NC_012563.1 identified by match to protein family HMM PF00376; match to protein family HMM PF06445; MerR family transcriptional regulator 2535031 7764896 CLM_2452 Clostridium botulinum A2 str. Kyoto MerR family transcriptional regulator YP_002804608.1 2534213 D 536232 CDS YP_002804609.1 226949518 7764407 complement(2535240..2536643) 1 NC_012563.1 identified by match to protein family HMM PF00324; amino acid permease family protein 2536643 7764407 CLM_2453 Clostridium botulinum A2 str. Kyoto amino acid permease family protein YP_002804609.1 2535240 R 536232 CDS YP_002804610.1 226949519 7767476 complement(2537079..2537621) 1 NC_012563.1 identified by match to protein family HMM PF01661; hypothetical protein 2537621 7767476 CLM_2454 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804610.1 2537079 R 536232 CDS YP_002804611.1 226949520 7767669 complement(2538002..2538307) 1 NC_012563.1 identified by match to protein family HMM PF06961; hypothetical protein 2538307 7767669 CLM_2455 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804611.1 2538002 R 536232 CDS YP_002804612.1 226949521 7766912 2538618..2538743 1 NC_012563.1 hypothetical protein 2538743 7766912 CLM_2456 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804612.1 2538618 D 536232 CDS YP_002804613.1 226949522 7764902 2538762..2539193 1 NC_012563.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 2539193 7764902 CLM_2457 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002804613.1 2538762 D 536232 CDS YP_002804614.1 226949523 7765986 2539196..2539588 1 NC_012563.1 hypothetical protein 2539588 7765986 CLM_2458 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804614.1 2539196 D 536232 CDS YP_002804615.1 226949524 7766452 complement(2539687..2539821) 1 NC_012563.1 hypothetical protein 2539821 7766452 CLM_2459 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804615.1 2539687 R 536232 CDS YP_002804616.1 226949525 7767644 complement(2540010..2540807) 1 NC_012563.1 identified by match to protein family HMM PF02110; hydroxyethylthiazole kinase 2540807 thiM 7767644 thiM Clostridium botulinum A2 str. Kyoto hydroxyethylthiazole kinase YP_002804616.1 2540010 R 536232 CDS YP_002804617.1 226949526 7764281 complement(2540785..2541354) 1 NC_012563.1 identified by match to protein family HMM TIGR02359; thiW protein 2541354 thiW 7764281 thiW Clostridium botulinum A2 str. Kyoto thiW protein YP_002804617.1 2540785 R 536232 CDS YP_002804618.1 226949527 7765368 complement(2541533..2541634) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2541634 7765368 CLM_2462 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804618.1 2541533 R 536232 CDS YP_002804619.1 226949528 7765450 complement(2541797..2542234) 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2542234 7765450 CLM_2464 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002804619.1 2541797 R 536232 CDS YP_002804620.1 226949529 7766974 complement(2542362..2543090) 1 NC_012563.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 2543090 7766974 CLM_2465 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002804620.1 2542362 R 536232 CDS YP_002804621.1 226949530 7768009 complement(2543275..2543547) 1 NC_012563.1 hypothetical protein 2543547 7768009 CLM_2466 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804621.1 2543275 R 536232 CDS YP_002804622.1 226949531 7765604 complement(2543832..2544515) 1 NC_012563.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 2544515 bioD 7765604 bioD Clostridium botulinum A2 str. Kyoto dithiobiotin synthetase YP_002804622.1 2543832 R 536232 CDS YP_002804623.1 226949532 7765676 complement(2544518..2545474) 1 NC_012563.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433; biotin synthase 2545474 bioB 7765676 bioB Clostridium botulinum A2 str. Kyoto biotin synthase YP_002804623.1 2544518 R 536232 CDS YP_002804624.1 226949533 7768045 complement(2545467..2546027) 1 NC_012563.1 identified by match to protein family HMM PF02632; BioY family protein 2546027 7768045 CLM_2469 Clostridium botulinum A2 str. Kyoto BioY family protein YP_002804624.1 2545467 R 536232 CDS YP_002804625.1 226949534 7767101 complement(2546164..2546316) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 2546316 7767101 CLM_2470 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804625.1 2546164 R 536232 CDS YP_002804626.1 226949535 7767030 complement(2546375..2546971) 1 NC_012563.1 hypothetical protein 2546971 7767030 CLM_2471 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804626.1 2546375 R 536232 CDS YP_002804627.1 226949536 7766124 2547149..2548942 1 NC_012563.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321; metallopeptidase, family M24 2548942 7766124 CLM_2472 Clostridium botulinum A2 str. Kyoto metallopeptidase, family M24 YP_002804627.1 2547149 D 536232 CDS YP_002804628.1 226949537 7765234 2548973..2550370 1 NC_012563.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter 2550370 7765234 CLM_2473 Clostridium botulinum A2 str. Kyoto amino acid/peptide transporter YP_002804628.1 2548973 D 536232 CDS YP_002804629.1 226949538 7764439 complement(2550626..2550745) 1 NC_012563.1 hypothetical protein 2550745 7764439 CLM_2474 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804629.1 2550626 R 536232 CDS YP_002804630.1 226949539 7766532 complement(2550924..2551172) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2551172 7766532 CLM_2475 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804630.1 2550924 R 536232 CDS YP_002804631.1 226949540 7765213 complement(2551435..2551704) 1 NC_012563.1 hypothetical protein 2551704 7765213 CLM_2476 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804631.1 2551435 R 536232 CDS YP_002804632.1 226949541 7764912 complement(2552007..2552423) 1 NC_012563.1 identified by match to protein family HMM PF07485; hypothetical protein 2552423 7764912 CLM_2477 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804632.1 2552007 R 536232 CDS YP_002804633.1 226949542 7767434 2552926..2553075 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2553075 7767434 CLM_2478 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804633.1 2552926 D 536232 CDS YP_002804634.1 226949543 7766013 complement(2553240..2554241) 1 NC_012563.1 identified by match to protein family HMM PF02275; match to protein family HMM PF03417; choloylglycine hydrolase family protein 2554241 7766013 CLM_2479 Clostridium botulinum A2 str. Kyoto choloylglycine hydrolase family protein YP_002804634.1 2553240 R 536232 CDS YP_002804635.1 226949544 7765580 complement(2554439..2555020) 1 NC_012563.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358; hypothetical protein 2555020 7765580 CLM_2480 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804635.1 2554439 R 536232 CDS YP_002804636.1 226949545 7767856 complement(2555449..2555646) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2555646 7767856 CLM_2481 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804636.1 2555449 R 536232 CDS YP_002804637.1 226949546 7766774 complement(2555825..2555953) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative; hypothetical protein 2555953 7766774 CLM_2482 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804637.1 2555825 R 536232 CDS YP_002804638.1 226949547 7766048 complement(2556006..2556209) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2556209 7766048 CLM_2483 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804638.1 2556006 R 536232 CDS YP_002804639.1 226949548 7765123 complement(2556520..2556642) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2556642 7765123 CLM_2484 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804639.1 2556520 R 536232 CDS YP_002804640.1 226949549 7767855 2557022..2557210 1 NC_012563.1 hypothetical protein 2557210 7767855 CLM_2485 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804640.1 2557022 D 536232 CDS YP_002804641.1 226949550 7766733 2557852..2558202 1 NC_012563.1 identified by match to protein family HMM PF01381; XRE family transcriptional regulator 2558202 7766733 CLM_2486 Clostridium botulinum A2 str. Kyoto XRE family transcriptional regulator YP_002804641.1 2557852 D 536232 CDS YP_002804642.1 226949551 7766065 complement(2558210..2560321) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; hypothetical protein 2560321 7766065 CLM_2487 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804642.1 2558210 R 536232 CDS YP_002804643.1 226949552 7764997 complement(2560331..2560540) 1 NC_012563.1 hypothetical protein 2560540 7764997 CLM_2488 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804643.1 2560331 R 536232 CDS YP_002804644.1 226949553 7767328 complement(2560546..2560782) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2560782 7767328 CLM_2489 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804644.1 2560546 R 536232 CDS YP_002804645.1 226949554 7766074 complement(2560795..2561199) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2561199 7766074 CLM_2490 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804645.1 2560795 R 536232 CDS YP_002804646.1 226949555 7764947 2561226..2561339 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2561339 7764947 CLM_2491 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804646.1 2561226 D 536232 CDS YP_002804647.1 226949556 7767521 complement(2561559..2561726) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2561726 7767521 CLM_2492 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804647.1 2561559 R 536232 CDS YP_002804648.1 226949557 7765180 complement(2561916..2562239) 1 NC_012563.1 identified by match to protein family HMM PF01381; putative DNA-binding protein 2562239 7765180 CLM_2493 Clostridium botulinum A2 str. Kyoto putative DNA-binding protein YP_002804648.1 2561916 R 536232 CDS YP_002804649.1 226949558 7764345 2562527..2563075 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2563075 7764345 CLM_2494 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804649.1 2562527 D 536232 CDS YP_002804650.1 226949559 7765492 complement(2564259..2564489) 1 NC_012563.1 hypothetical protein 2564489 7765492 CLM_2495 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804650.1 2564259 R 536232 CDS YP_002804651.1 226949560 7764517 complement(2564847..2565212) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2565212 7764517 CLM_2496 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804651.1 2564847 R 536232 CDS YP_002804652.1 226949561 7767748 complement(2565407..2566396) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2566396 7767748 CLM_2497 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804652.1 2565407 R 536232 CDS YP_002804653.1 226949562 7766870 complement(2566644..2567405) 1 NC_012563.1 identified by match to protein family HMM PF01520; match to protein family HMM PF08239; N-acetylmuramoyl-L-alanine amidase 2567405 7766870 CLM_2498 Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase YP_002804653.1 2566644 R 536232 CDS YP_002804654.1 226949563 7765953 complement(2567443..2567637) 1 NC_012563.1 hypothetical protein 2567637 7765953 CLM_2500 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804654.1 2567443 R 536232 CDS YP_002804655.1 226949564 7767468 complement(2567654..2567908) 1 NC_012563.1 hypothetical protein 2567908 7767468 CLM_2501 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804655.1 2567654 R 536232 CDS YP_002804656.1 226949565 7767716 complement(2568015..2568176) 1 NC_012563.1 hypothetical protein 2568176 7767716 CLM_2502 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804656.1 2568015 R 536232 CDS YP_002804657.1 226949566 7765540 complement(2568176..2568472) 1 NC_012563.1 hypothetical protein 2568472 7765540 CLM_2503 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804657.1 2568176 R 536232 CDS YP_002804658.1 226949567 7764328 complement(2568488..2569654) 1 NC_012563.1 tail fiber protein 2569654 7764328 CLM_2504 Clostridium botulinum A2 str. Kyoto tail fiber protein YP_002804658.1 2568488 R 536232 CDS YP_002804659.1 226949568 7767197 complement(2569657..2570292) 1 NC_012563.1 hypothetical protein 2570292 7767197 CLM_2505 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804659.1 2569657 R 536232 CDS YP_002804660.1 226949569 7767084 complement(2570289..2571419) 1 NC_012563.1 identified by match to protein family HMM PF04865; putative baseplate J-like protein 2571419 7767084 CLM_2506 Clostridium botulinum A2 str. Kyoto putative baseplate J-like protein YP_002804660.1 2570289 R 536232 CDS YP_002804661.1 226949570 7765835 complement(2571425..2571877) 1 NC_012563.1 hypothetical protein 2571877 7765835 CLM_2507 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804661.1 2571425 R 536232 CDS YP_002804662.1 226949571 7764759 complement(2571870..2572202) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2572202 7764759 CLM_2508 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804662.1 2571870 R 536232 CDS YP_002804663.1 226949572 7765842 complement(2572186..2573154) 1 NC_012563.1 hypothetical protein 2573154 7765842 CLM_2509 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804663.1 2572186 R 536232 CDS YP_002804664.1 226949573 7764728 complement(2573154..2573843) 1 NC_012563.1 hypothetical protein 2573843 7764728 CLM_2510 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804664.1 2573154 R 536232 CDS YP_002804665.1 226949574 7765472 complement(2573874..2574386) 1 NC_012563.1 hypothetical protein 2574386 7765472 CLM_2511 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804665.1 2573874 R 536232 CDS YP_002804666.1 226949575 7766260 complement(2574440..2577418) 1 NC_012563.1 identified by match to protein family HMM TIGR01760; phage tail tape measure protein, TP901 family 2577418 7766260 CLM_2512 Clostridium botulinum A2 str. Kyoto phage tail tape measure protein, TP901 family YP_002804666.1 2574440 R 536232 CDS YP_002804667.1 226949576 7764830 complement(2577419..2577565) 1 NC_012563.1 hypothetical protein 2577565 7764830 CLM_2513 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804667.1 2577419 R 536232 CDS YP_002804668.1 226949577 7765916 complement(2577601..2578035) 1 NC_012563.1 identified by match to protein family HMM PF08890; hypothetical protein 2578035 7765916 CLM_2514 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804668.1 2577601 R 536232 CDS YP_002804669.1 226949578 7766501 complement(2578059..2578469) 1 NC_012563.1 identified by match to protein family HMM PF09393; hypothetical protein 2578469 7766501 CLM_2515 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804669.1 2578059 R 536232 CDS YP_002804670.1 226949579 7767661 complement(2578482..2579888) 1 NC_012563.1 putative tail sheath protein 2579888 7767661 CLM_2516 Clostridium botulinum A2 str. Kyoto putative tail sheath protein YP_002804670.1 2578482 R 536232 CDS YP_002804671.1 226949580 7766463 complement(2579888..2580079) 1 NC_012563.1 hypothetical protein 2580079 7766463 CLM_2517 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804671.1 2579888 R 536232 CDS YP_002804672.1 226949581 7767608 complement(2580090..2580911) 1 NC_012563.1 hypothetical protein 2580911 7767608 CLM_2518 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804672.1 2580090 R 536232 CDS YP_002804673.1 226949582 7764209 complement(2580914..2581321) 1 NC_012563.1 hypothetical protein 2581321 7764209 CLM_2519 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804673.1 2580914 R 536232 CDS YP_002804674.1 226949583 7765272 complement(2581323..2581709) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2581709 7765272 CLM_2520 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804674.1 2581323 R 536232 CDS YP_002804675.1 226949584 7764945 complement(2581710..2582030) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2582030 7764945 CLM_2521 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804675.1 2581710 R 536232 CDS YP_002804676.1 226949585 7765316 complement(2582033..2582224) 1 NC_012563.1 hypothetical protein 2582224 7765316 CLM_2522 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804676.1 2582033 R 536232 CDS YP_002804677.1 226949586 7766651 complement(2582281..2583333) 1 NC_012563.1 hypothetical protein 2583333 7766651 CLM_2523 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804677.1 2582281 R 536232 CDS YP_002804678.1 226949587 7767467 complement(2583347..2583739) 1 NC_012563.1 hypothetical protein 2583739 7767467 CLM_2524 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804678.1 2583347 R 536232 CDS YP_002804679.1 226949588 7765520 complement(2583760..2584374) 1 NC_012563.1 phage scaffold protein 2584374 7765520 CLM_2525 Clostridium botulinum A2 str. Kyoto phage scaffold protein YP_002804679.1 2583760 R 536232 CDS YP_002804680.1 226949589 7765844 complement(2584441..2584584) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2584584 7765844 CLM_2526 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804680.1 2584441 R 536232 CDS YP_002804681.1 226949590 7766758 complement(2584590..2586248) 1 NC_012563.1 hypothetical protein 2586248 7766758 CLM_2527 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804681.1 2584590 R 536232 CDS YP_002804682.1 226949591 7768044 complement(2586248..2587774) 1 NC_012563.1 hypothetical protein 2587774 7768044 CLM_2528 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804682.1 2586248 R 536232 CDS YP_002804683.1 226949592 7767696 complement(2587774..2589129) 1 NC_012563.1 identified by match to protein family HMM PF04466; match to protein family HMM PF07570; match to protein family HMM TIGR01547; phage terminase large subunit, pbsx family 2589129 7767696 CLM_2529 Clostridium botulinum A2 str. Kyoto phage terminase large subunit, pbsx family YP_002804683.1 2587774 R 536232 CDS YP_002804684.1 226949593 7765165 complement(2589129..2589836) 1 NC_012563.1 phage protein 2589836 7765165 CLM_2530 Clostridium botulinum A2 str. Kyoto phage protein YP_002804684.1 2589129 R 536232 CDS YP_002804685.1 226949594 7765025 complement(2589932..2590171) 1 NC_012563.1 identified by match to protein family HMM PF03413; peptidase domain-containing protein 2590171 7765025 CLM_2531 Clostridium botulinum A2 str. Kyoto peptidase domain-containing protein YP_002804685.1 2589932 R 536232 CDS YP_002804686.1 226949595 7767208 complement(2590287..2590505) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2590505 7767208 CLM_2532 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804686.1 2590287 R 536232 CDS YP_002804687.1 226949596 7764999 complement(2590597..2591832) 1 NC_012563.1 identified by match to protein family HMM PF02368; Ig group 2 domain-containing protein 2591832 7764999 CLM_2533 Clostridium botulinum A2 str. Kyoto Ig group 2 domain-containing protein YP_002804687.1 2590597 R 536232 CDS YP_002804688.1 226949597 7765445 complement(2592246..2592683) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2592683 7765445 CLM_2534 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804688.1 2592246 R 536232 CDS YP_002804689.1 226949598 7766221 complement(2592694..2592927) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2592927 7766221 CLM_2535 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804689.1 2592694 R 536232 CDS YP_002804690.1 226949599 7764788 complement(2592929..2593522) 1 NC_012563.1 identified by match to protein family HMM PF09643; phage protein 2593522 7764788 CLM_2536 Clostridium botulinum A2 str. Kyoto phage protein YP_002804690.1 2592929 R 536232 CDS YP_002804691.1 226949600 7765833 complement(2593611..2593838) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2593838 7765833 CLM_2537 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804691.1 2593611 R 536232 CDS YP_002804692.1 226949601 7766930 complement(2593859..2594686) 1 NC_012563.1 identified by match to protein family HMM PF02086; D12 class N6 adenine-specific DNA methyltransferase superfamily protein 2594686 7766930 CLM_2538 Clostridium botulinum A2 str. Kyoto D12 class N6 adenine-specific DNA methyltransferase superfamily protein YP_002804692.1 2593859 R 536232 CDS YP_002804693.1 226949602 7768090 complement(2594701..2594916) 1 NC_012563.1 hypothetical protein 2594916 7768090 CLM_2539 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804693.1 2594701 R 536232 CDS YP_002804694.1 226949603 7766952 complement(2594933..2595928) 1 NC_012563.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; phage integrase family site-specific recombinase 2595928 7766952 CLM_2540 Clostridium botulinum A2 str. Kyoto phage integrase family site-specific recombinase YP_002804694.1 2594933 R 536232 CDS YP_002804695.1 226949604 7766611 complement(2596000..2596167) 1 NC_012563.1 hypothetical protein 2596167 7766611 CLM_2541 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804695.1 2596000 R 536232 CDS YP_002804696.1 226949605 7767475 complement(2596262..2596408) 1 NC_012563.1 hypothetical protein 2596408 7767475 CLM_2542 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804696.1 2596262 R 536232 CDS YP_002804697.1 226949606 7764428 complement(2596442..2596612) 1 NC_012563.1 hypothetical protein 2596612 7764428 CLM_2543 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804697.1 2596442 R 536232 CDS YP_002804698.1 226949607 7767622 complement(2596645..2597034) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2597034 7767622 CLM_2544 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804698.1 2596645 R 536232 CDS YP_002804699.1 226949608 7764307 complement(2597168..2597350) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2597350 7764307 CLM_2545 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804699.1 2597168 R 536232 CDS YP_002804700.1 226949609 7765379 complement(2597411..2597716) 1 NC_012563.1 hypothetical protein 2597716 7765379 CLM_2546 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804700.1 2597411 R 536232 CDS YP_002804701.1 226949610 7768038 complement(2597750..2597902) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2597902 7768038 CLM_2547 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804701.1 2597750 R 536232 CDS YP_002804702.1 226949611 7765138 complement(2597934..2598122) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2598122 7765138 CLM_2548 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804702.1 2597934 R 536232 CDS YP_002804703.1 226949612 7765792 complement(2598168..2598341) 1 NC_012563.1 hypothetical protein 2598341 7765792 CLM_2549 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804703.1 2598168 R 536232 CDS YP_002804704.1 226949613 7766442 complement(2598393..2598611) 1 NC_012563.1 hypothetical protein 2598611 7766442 CLM_2550 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804704.1 2598393 R 536232 CDS YP_002804705.1 226949614 7768016 complement(2598635..2598982) 1 NC_012563.1 hypothetical protein 2598982 7768016 CLM_2551 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804705.1 2598635 R 536232 CDS YP_002804706.1 226949615 7764911 complement(2598985..2599389) 1 NC_012563.1 identified by match to protein family HMM PF06356; hypothetical protein 2599389 7764911 CLM_2552 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804706.1 2598985 R 536232 CDS YP_002804707.1 226949616 7767941 complement(2599386..2599550) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2599550 7767941 CLM_2553 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804707.1 2599386 R 536232 CDS YP_002804708.1 226949617 7767036 complement(2599540..2599905) 1 NC_012563.1 phage protein 2599905 7767036 CLM_2554 Clostridium botulinum A2 str. Kyoto phage protein YP_002804708.1 2599540 R 536232 CDS YP_002804709.1 226949618 7765175 complement(2599982..2600695) 1 NC_012563.1 hypothetical protein 2600695 7765175 CLM_2555 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804709.1 2599982 R 536232 CDS YP_002804710.1 226949619 7764364 complement(2600722..2601114) 1 NC_012563.1 replication terminator protein, phage associated 2601114 7764364 CLM_2556 Clostridium botulinum A2 str. Kyoto replication terminator protein, phage associated YP_002804710.1 2600722 R 536232 CDS YP_002804711.1 226949620 7767637 complement(2601212..2601592) 1 NC_012563.1 identified by match to protein family HMM PF03819; MazG nucleotide pyrophosphohydrolase domain-containing protein 2601592 7767637 CLM_2557 Clostridium botulinum A2 str. Kyoto MazG nucleotide pyrophosphohydrolase domain-containing protein YP_002804711.1 2601212 R 536232 CDS YP_002804712.1 226949621 7767694 complement(2601592..2601831) 1 NC_012563.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439; AbrB family transcriptional regulator 2601831 7767694 CLM_2558 Clostridium botulinum A2 str. Kyoto AbrB family transcriptional regulator YP_002804712.1 2601592 R 536232 CDS YP_002804713.1 226949622 7766797 complement(2601834..2602154) 1 NC_012563.1 hypothetical protein 2602154 7766797 CLM_2559 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804713.1 2601834 R 536232 CDS YP_002804714.1 226949623 7767698 complement(2602156..2603034) 1 NC_012563.1 identified by match to protein family HMM PF00249; phage protein 2603034 7767698 CLM_2560 Clostridium botulinum A2 str. Kyoto phage protein YP_002804714.1 2602156 R 536232 CDS YP_002804715.1 226949624 7767479 complement(2603046..2603285) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2603285 7767479 CLM_2561 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804715.1 2603046 R 536232 CDS YP_002804716.1 226949625 7766929 complement(2603302..2604105) 1 NC_012563.1 hypothetical protein 2604105 7766929 CLM_2562 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804716.1 2603302 R 536232 CDS YP_002804717.1 226949626 7765296 complement(2604065..2604937) 1 NC_012563.1 identified by match to protein family HMM PF09681; match to protein family HMM TIGR01714; putative phage replisome organizer 2604937 7765296 CLM_2563 Clostridium botulinum A2 str. Kyoto putative phage replisome organizer YP_002804717.1 2604065 R 536232 CDS YP_002804718.1 226949627 7764742 complement(2604960..2605259) 1 NC_012563.1 hypothetical protein 2605259 7764742 CLM_2564 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804718.1 2604960 R 536232 CDS YP_002804719.1 226949628 7768104 complement(2605353..2605529) 1 NC_012563.1 hypothetical protein 2605529 7768104 CLM_2565 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804719.1 2605353 R 536232 CDS YP_002804720.1 226949629 7765553 complement(2605545..2605691) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2605691 7765553 CLM_2566 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804720.1 2605545 R 536232 CDS YP_002804721.1 226949630 7765878 complement(2605694..2606554) 1 NC_012563.1 hypothetical protein 2606554 7765878 CLM_2567 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804721.1 2605694 R 536232 CDS YP_002804722.1 226949631 7767488 complement(2606566..2607051) 1 NC_012563.1 identified by match to protein family HMM PF05565; hypothetical protein 2607051 7767488 CLM_2568 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804722.1 2606566 R 536232 CDS YP_002804723.1 226949632 7766197 complement(2607183..2607347) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2607347 7766197 CLM_2569 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804723.1 2607183 R 536232 CDS YP_002804724.1 226949633 7765683 complement(2607356..2607514) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2607514 7765683 CLM_2570 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804724.1 2607356 R 536232 CDS YP_002804725.1 226949634 7764994 complement(2607567..2607719) 1 NC_012563.1 hypothetical protein 2607719 7764994 CLM_2571 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804725.1 2607567 R 536232 CDS YP_002804726.1 226949635 7767183 complement(2607740..2607949) 1 NC_012563.1 hypothetical protein 2607949 7767183 CLM_2572 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804726.1 2607740 R 536232 CDS YP_002804727.1 226949636 7766092 complement(2607961..2608749) 1 NC_012563.1 identified by match to protein family HMM PF03374; match to protein family HMM PF08346; phage antirepressor protein 2608749 7766092 CLM_2573 Clostridium botulinum A2 str. Kyoto phage antirepressor protein YP_002804727.1 2607961 R 536232 CDS YP_002804728.1 226949637 7765422 complement(2608803..2609024) 1 NC_012563.1 identified by match to protein family HMM PF01381; hypothetical protein 2609024 7765422 CLM_2574 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804728.1 2608803 R 536232 CDS YP_002804729.1 226949638 7764357 2609157..2609615 1 NC_012563.1 identified by match to protein family HMM PF01381; immunity repressor protein 2609615 7764357 CLM_2575 Clostridium botulinum A2 str. Kyoto immunity repressor protein YP_002804729.1 2609157 D 536232 CDS YP_002804730.1 226949639 7767058 2609662..2610096 1 NC_012563.1 identified by match to protein family HMM PF06114; hypothetical protein 2610096 7767058 CLM_2576 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804730.1 2609662 D 536232 CDS YP_002804731.1 226949640 7765933 2610239..2611600 1 NC_012563.1 phage protein 2611600 7765933 CLM_2577 Clostridium botulinum A2 str. Kyoto phage protein YP_002804731.1 2610239 D 536232 CDS YP_002804732.1 226949641 7764557 2611695..2613317 1 NC_012563.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508; resolvase 2613317 7764557 CLM_2578 Clostridium botulinum A2 str. Kyoto resolvase YP_002804732.1 2611695 D 536232 CDS YP_002804733.1 226949642 7767907 2613606..2614307 1 NC_012563.1 hypothetical protein 2614307 7767907 CLM_2579 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804733.1 2613606 D 536232 CDS YP_002804734.1 226949643 7766183 complement(2614402..2614569) 1 NC_012563.1 hypothetical protein 2614569 7766183 CLM_2580 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804734.1 2614402 R 536232 CDS YP_002804735.1 226949644 7765322 complement(2614870..2615277) 1 NC_012563.1 hypothetical protein 2615277 7765322 CLM_2581 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804735.1 2614870 R 536232 CDS YP_002804736.1 226949645 7765932 complement(2615358..2615951) 1 NC_012563.1 putative lipoprotein 2615951 7765932 CLM_2582 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002804736.1 2615358 R 536232 CDS YP_002804737.1 226949646 7767083 complement(2616125..2616574) 1 NC_012563.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2616574 msrB 7767083 msrB Clostridium botulinum A2 str. Kyoto methionine sulfoxide reductase B YP_002804737.1 2616125 R 536232 CDS YP_002804738.1 226949647 7764993 complement(2616806..2617402) 1 NC_012563.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777; Mn/Fe superoxide dismutase 2617402 sodF 7764993 sodF Clostridium botulinum A2 str. Kyoto Mn/Fe superoxide dismutase YP_002804738.1 2616806 R 536232 CDS YP_002804739.1 226949648 7766095 complement(2617514..2619259) 1 NC_012563.1 identified by match to protein family HMM PF00005; putative ABC transporter ATP-binding/permease 2619259 7766095 CLM_2585 Clostridium botulinum A2 str. Kyoto putative ABC transporter ATP-binding/permease YP_002804739.1 2617514 R 536232 CDS YP_002804740.1 226949649 7766273 complement(2619252..2621051) 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; putative ABC transporter ATP-binding/permease 2621051 7766273 CLM_2586 Clostridium botulinum A2 str. Kyoto putative ABC transporter ATP-binding/permease YP_002804740.1 2619252 R 536232 CDS YP_002804741.1 226949650 7767338 complement(2621331..2622290) 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 2622290 7767338 CLM_2587 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002804741.1 2621331 R 536232 CDS YP_002804742.1 226949651 7765648 complement(2622537..2622650) 1 NC_012563.1 hypothetical protein 2622650 7765648 CLM_2588 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804742.1 2622537 R 536232 CDS YP_002804743.1 226949652 7766230 complement(2622797..2623531) 1 NC_012563.1 hypothetical protein 2623531 7766230 CLM_2589 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804743.1 2622797 R 536232 CDS YP_002804744.1 226949653 7766703 complement(2623567..2624313) 1 NC_012563.1 hypothetical protein 2624313 7766703 CLM_2590 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804744.1 2623567 R 536232 CDS YP_002804745.1 226949654 7767275 complement(2624306..2625226) 1 NC_012563.1 identified by match to protein family HMM PF00005; antibiotic ABC transporter ATP-binding protein 2625226 7767275 CLM_2591 Clostridium botulinum A2 str. Kyoto antibiotic ABC transporter ATP-binding protein YP_002804745.1 2624306 R 536232 CDS YP_002804746.1 226949655 7765202 complement(2625428..2626339) 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 2626339 7765202 CLM_2592 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002804746.1 2625428 R 536232 CDS YP_002804747.1 226949656 7765099 complement(2626336..2627043) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 2627043 7765099 CLM_2593 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002804747.1 2626336 R 536232 CDS YP_002804748.1 226949657 7767790 2627398..2628159 1 NC_012563.1 identified by match to protein family HMM PF00929; exonuclease family protein 2628159 7767790 CLM_2594 Clostridium botulinum A2 str. Kyoto exonuclease family protein YP_002804748.1 2627398 D 536232 CDS YP_002804749.1 226949658 7766915 complement(2628193..2628495) 1 NC_012563.1 identified by match to protein family HMM PF07876; stress responsive A/B barrel domain-containing protein 2628495 7766915 CLM_2595 Clostridium botulinum A2 str. Kyoto stress responsive A/B barrel domain-containing protein YP_002804749.1 2628193 R 536232 CDS YP_002804750.1 226949659 7764859 complement(2628578..2629414) 1 NC_012563.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 2629414 7764859 CLM_2596 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002804750.1 2628578 R 536232 CDS YP_002804751.1 226949660 7764521 complement(2629717..2630169) 1 NC_012563.1 identified by match to protein family HMM PF01327; match to protein family HMM TIGR00079; peptide deformylase 2630169 def 7764521 def Clostridium botulinum A2 str. Kyoto peptide deformylase YP_002804751.1 2629717 R 536232 CDS YP_002804752.1 226949661 7767610 complement(2630170..2630406) 1 NC_012563.1 identified by match to protein family HMM PF01381; putative DNA-binding protein 2630406 7767610 CLM_2598 Clostridium botulinum A2 str. Kyoto putative DNA-binding protein YP_002804752.1 2630170 R 536232 CDS YP_002804753.1 226949662 7766327 complement(2630647..2631468) 1 NC_012563.1 involved in assembly of spore coat proteins such as GerQ by catalyzing epsilon-(gamma-glutamyl)lysine cross links; transglutaminase 2631468 tgl 7766327 tgl Clostridium botulinum A2 str. Kyoto transglutaminase YP_002804753.1 2630647 R 536232 CDS YP_002804754.1 226949663 7764370 complement(2631465..2632460) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2632460 7764370 CLM_2600 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804754.1 2631465 R 536232 CDS YP_002804755.1 226949664 7765983 complement(2632809..2632922) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2632922 7765983 CLM_2601 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804755.1 2632809 R 536232 CDS YP_002804756.1 226949665 7767117 complement(2633537..2633689) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; O-methyltransferase domain-containing protein 2633689 7767117 CLM_2602 Clostridium botulinum A2 str. Kyoto O-methyltransferase domain-containing protein YP_002804756.1 2633537 R 536232 CDS YP_002804757.1 226949666 7765049 complement(2634160..2634756) 1 NC_012563.1 hypothetical protein 2634756 7765049 CLM_2603 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804757.1 2634160 R 536232 CDS YP_002804758.1 226949667 7765671 complement(2634972..2635097) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2635097 7765671 CLM_2604 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804758.1 2634972 R 536232 CDS YP_002804759.1 226949668 7766787 2635433..2636806 1 NC_012563.1 identified by match to protein family HMM PF02366; hypothetical protein 2636806 7766787 CLM_2605 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804759.1 2635433 D 536232 CDS YP_002804760.1 226949669 7766418 complement(2637008..2637313) 1 NC_012563.1 hypothetical protein 2637313 7766418 CLM_2606 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804760.1 2637008 R 536232 CDS YP_002804761.1 226949670 7764535 complement(2637306..2637830) 1 NC_012563.1 hypothetical protein 2637830 7764535 CLM_2607 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804761.1 2637306 R 536232 CDS YP_002804762.1 226949671 7765629 complement(2637811..2638263) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2638263 7765629 CLM_2608 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804762.1 2637811 R 536232 CDS YP_002804763.1 226949672 7766204 complement(2638260..2638772) 1 NC_012563.1 identified by match to protein family HMM PF04542; match to protein family HMM TIGR02937; ECF family RNA polymerase sigma-70 factor 2638772 7766204 CLM_2609 Clostridium botulinum A2 str. Kyoto ECF family RNA polymerase sigma-70 factor YP_002804763.1 2638260 R 536232 CDS YP_002804764.1 226949673 7767331 complement(2639225..2640331) 1 NC_012563.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912; spore germination protein 2640331 7767331 CLM_2610 Clostridium botulinum A2 str. Kyoto spore germination protein YP_002804764.1 2639225 R 536232 CDS YP_002804765.1 226949674 7765378 complement(2640943..2641302) 1 NC_012563.1 LuxR family transcriptional regulator 2641302 7765378 CLM_2611 Clostridium botulinum A2 str. Kyoto LuxR family transcriptional regulator YP_002804765.1 2640943 R 536232 CDS YP_002804766.1 226949675 7764300 complement(2641373..2641855) 1 NC_012563.1 hypothetical protein 2641855 7764300 CLM_2612 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804766.1 2641373 R 536232 CDS YP_002804767.1 226949676 7766584 complement(2644605..2645957) 1 NC_012563.1 identified by match to protein family HMM PF01743; match to protein family HMM PF01966; match to protein family HMM TIGR00277; polyA polymerase family protein 2645957 7766584 CLM_2616 Clostridium botulinum A2 str. Kyoto polyA polymerase family protein YP_002804767.1 2644605 R 536232 CDS YP_002804768.1 226949677 7767882 complement(2645947..2646957) 1 NC_012563.1 hypothetical protein 2646957 7767882 CLM_2617 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804768.1 2645947 R 536232 CDS YP_002804769.1 226949678 7766196 complement(2647335..2647502) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2647502 7766196 CLM_2618 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804769.1 2647335 R 536232 CDS YP_002804770.1 226949679 7766081 complement(2647523..2647837) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02517; caax amino protease family protein 2647837 7766081 CLM_2619 Clostridium botulinum A2 str. Kyoto caax amino protease family protein YP_002804770.1 2647523 R 536232 CDS YP_002804771.1 226949680 7764685 complement(2647951..2648115) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2648115 7764685 CLM_2620 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804771.1 2647951 R 536232 CDS YP_002804772.1 226949681 7766752 2648540..2649226 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; membrane protein 2649226 7766752 CLM_2621 Clostridium botulinum A2 str. Kyoto membrane protein YP_002804772.1 2648540 D 536232 CDS YP_002804773.1 226949682 7767863 complement(2649269..2650519) 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 2650519 7767863 CLM_2622 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002804773.1 2649269 R 536232 CDS YP_002804774.1 226949683 7767095 complement(2650512..2651192) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 2651192 7767095 CLM_2623 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002804774.1 2650512 R 536232 CDS YP_002804775.1 226949684 7766134 complement(2651185..2651724) 1 NC_012563.1 identified by match to protein family HMM PF00627; UBA/TS-N domain-containing protein 2651724 7766134 CLM_2624 Clostridium botulinum A2 str. Kyoto UBA/TS-N domain-containing protein YP_002804775.1 2651185 R 536232 CDS YP_002804776.1 226949685 7765026 complement(2651875..2652417) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2652417 7765026 CLM_2625 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804776.1 2651875 R 536232 CDS YP_002804777.1 226949686 7767182 complement(2652776..2653585) 1 NC_012563.1 hypothetical protein 2653585 7767182 CLM_2626 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804777.1 2652776 R 536232 CDS YP_002804778.1 226949687 7766570 complement(2653461..2653619) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2653619 7766570 CLM_2627 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804778.1 2653461 R 536232 CDS YP_002804779.1 226949688 7765918 2654321..2654569 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 2654569 7765918 CLM_2628 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002804779.1 2654321 D 536232 CDS YP_002804780.1 226949689 7765508 2654968..2655147 1 NC_012563.1 identified by match to protein family HMM PF07927; hypothetical protein 2655147 7765508 CLM_2629 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804780.1 2654968 D 536232 CDS YP_002804781.1 226949690 7764654 2655206..2655619 1 NC_012563.1 identified by match to protein family HMM PF03681; phage protein 2655619 7764654 CLM_2630 Clostridium botulinum A2 str. Kyoto phage protein YP_002804781.1 2655206 D 536232 CDS YP_002804782.1 226949691 7766763 complement(2656559..2657320) 1 NC_012563.1 identified by match to protein family HMM PF01520; match to protein family HMM PF08239; N-acetylmuramoyl-L-alanine amidase 2657320 7766763 CLM_2631 Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase YP_002804782.1 2656559 R 536232 CDS YP_002804783.1 226949692 7765872 complement(2657362..2657556) 1 NC_012563.1 hypothetical protein 2657556 7765872 CLM_2632 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804783.1 2657362 R 536232 CDS YP_002804784.1 226949693 7768100 complement(2657573..2657827) 1 NC_012563.1 hypothetical protein 2657827 7768100 CLM_2633 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804784.1 2657573 R 536232 CDS YP_002804785.1 226949694 7767708 complement(2657931..2658641) 1 NC_012563.1 phage protein 2658641 7767708 CLM_2634 Clostridium botulinum A2 str. Kyoto phage protein YP_002804785.1 2657931 R 536232 CDS YP_002804786.1 226949695 7767548 complement(2658865..2659332) 1 NC_012563.1 hypothetical protein 2659332 7767548 CLM_2635 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804786.1 2658865 R 536232 CDS YP_002804787.1 226949696 7766417 complement(2659997..2660386) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2660386 7766417 CLM_2636 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804787.1 2659997 R 536232 CDS YP_002804788.1 226949697 7765356 complement(2660508..2660717) 1 NC_012563.1 hypothetical protein 2660717 7765356 CLM_2637 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804788.1 2660508 R 536232 CDS YP_002804789.1 226949698 7767315 complement(2660733..2661038) 1 NC_012563.1 hypothetical protein 2661038 7767315 CLM_2638 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804789.1 2660733 R 536232 CDS YP_002804790.1 226949699 7767124 complement(2661054..2662298) 1 NC_012563.1 tail fiber protein H 2662298 7767124 CLM_2639 Clostridium botulinum A2 str. Kyoto tail fiber protein H YP_002804790.1 2661054 R 536232 CDS YP_002804791.1 226949700 7765995 complement(2662302..2662928) 1 NC_012563.1 hypothetical protein 2662928 7765995 CLM_2640 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804791.1 2662302 R 536232 CDS YP_002804792.1 226949701 7764921 complement(2662909..2664003) 1 NC_012563.1 identified by match to protein family HMM PF04865; putative baseplate J-like protein 2664003 7764921 CLM_2641 Clostridium botulinum A2 str. Kyoto putative baseplate J-like protein YP_002804792.1 2662909 R 536232 CDS YP_002804793.1 226949702 7764763 complement(2664004..2664411) 1 NC_012563.1 hypothetical protein 2664411 7764763 CLM_2642 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804793.1 2664004 R 536232 CDS YP_002804794.1 226949703 7767802 complement(2664414..2664758) 1 NC_012563.1 hypothetical protein 2664758 7767802 CLM_2643 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804794.1 2664414 R 536232 CDS YP_002804795.1 226949704 7766121 complement(2664768..2665742) 1 NC_012563.1 hypothetical protein 2665742 7766121 CLM_2644 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804795.1 2664768 R 536232 CDS YP_002804796.1 226949705 7766720 complement(2665754..2666434) 1 NC_012563.1 identified by match to protein family HMM PF01476; lysM domain-containing protein 2666434 7766720 CLM_2645 Clostridium botulinum A2 str. Kyoto lysM domain-containing protein YP_002804796.1 2665754 R 536232 CDS YP_002804797.1 226949706 7767381 complement(2666434..2668593) 1 NC_012563.1 putative tail length tape measure protein 2668593 7767381 CLM_2646 Clostridium botulinum A2 str. Kyoto putative tail length tape measure protein YP_002804797.1 2666434 R 536232 CDS YP_002804798.1 226949707 7764976 complement(2668679..2669257) 1 NC_012563.1 putative lipoprotein 2669257 7764976 CLM_2647 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002804798.1 2668679 R 536232 CDS YP_002804799.1 226949708 7764424 complement(2669322..2669417) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2669417 7764424 CLM_2648 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804799.1 2669322 R 536232 CDS YP_002804800.1 226949709 7766022 complement(2669498..2669911) 1 NC_012563.1 identified by match to protein family HMM PF08890; hypothetical protein 2669911 7766022 CLM_2649 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804800.1 2669498 R 536232 CDS YP_002804801.1 226949710 7765285 complement(2669927..2670391) 1 NC_012563.1 identified by match to protein family HMM PF09393; core tail protein 2670391 7765285 CLM_2650 Clostridium botulinum A2 str. Kyoto core tail protein YP_002804801.1 2669927 R 536232 CDS YP_002804802.1 226949711 7766484 complement(2670395..2671705) 1 NC_012563.1 hypothetical protein 2671705 7766484 CLM_2651 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804802.1 2670395 R 536232 CDS YP_002804803.1 226949712 7767594 complement(2671707..2671877) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2671877 7767594 CLM_2652 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804803.1 2671707 R 536232 CDS YP_002804804.1 226949713 7766937 complement(2671867..2672298) 1 NC_012563.1 hypothetical protein 2672298 7766937 CLM_2653 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804804.1 2671867 R 536232 CDS YP_002804805.1 226949714 7767089 complement(2672300..2672791) 1 NC_012563.1 phage protein 2672791 7767089 CLM_2654 Clostridium botulinum A2 str. Kyoto phage protein YP_002804805.1 2672300 R 536232 CDS YP_002804806.1 226949715 7766061 complement(2672791..2673174) 1 NC_012563.1 hypothetical protein 2673174 7766061 CLM_2655 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804806.1 2672791 R 536232 CDS YP_002804807.1 226949716 7766725 complement(2673176..2673520) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2673520 7766725 CLM_2656 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804807.1 2673176 R 536232 CDS YP_002804808.1 226949717 7767298 complement(2673534..2674499) 1 NC_012563.1 phage coat protein 2674499 7767298 CLM_2657 Clostridium botulinum A2 str. Kyoto phage coat protein YP_002804808.1 2673534 R 536232 CDS YP_002804809.1 226949718 7765033 complement(2674519..2675124) 1 NC_012563.1 identified by similarity to GB:CAA61868.1; match to protein family HMM PF06810; putative scaffold protein 2675124 7765033 CLM_2658 Clostridium botulinum A2 str. Kyoto putative scaffold protein YP_002804809.1 2674519 R 536232 CDS YP_002804810.1 226949719 7765564 complement(2675147..2675461) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 2675461 7765564 CLM_2659 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804810.1 2675147 R 536232 CDS YP_002804811.1 226949720 7766572 complement(2675547..2675741) 1 NC_012563.1 hypothetical protein 2675741 7766572 CLM_2660 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804811.1 2675547 R 536232 CDS YP_002804812.1 226949721 7766693 complement(2675774..2677582) 1 NC_012563.1 identified by match to protein family HMM PF04233; match to protein family HMM TIGR01641; prophage head protein 2677582 7766693 CLM_2661 Clostridium botulinum A2 str. Kyoto prophage head protein YP_002804812.1 2675774 R 536232 CDS YP_002804813.1 226949722 7767843 complement(2677554..2679005) 1 NC_012563.1 identified by match to protein family HMM PF05133; match to protein family HMM TIGR01538; phage portal protein, SPP1 family 2679005 7767843 CLM_2662 Clostridium botulinum A2 str. Kyoto phage portal protein, SPP1 family YP_002804813.1 2677554 R 536232 CDS YP_002804814.1 226949723 7766674 complement(2679018..2680256) 1 NC_012563.1 identified by match to protein family HMM PF04466; match to protein family HMM TIGR01547; phage terminase large subunit, pbsx family 2680256 7766674 CLM_2663 Clostridium botulinum A2 str. Kyoto phage terminase large subunit, pbsx family YP_002804814.1 2679018 R 536232 CDS YP_002804815.1 226949724 7767449 complement(2680246..2680815) 1 NC_012563.1 identified by match to protein family HMM PF03592; putative phage terminase small subunit 2680815 7767449 CLM_2664 Clostridium botulinum A2 str. Kyoto putative phage terminase small subunit YP_002804815.1 2680246 R 536232 CDS YP_002804816.1 226949725 7765042 2681020..2681157 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2681157 7765042 CLM_2665 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804816.1 2681020 D 536232 CDS YP_002804817.1 226949726 7765923 complement(2681387..2681866) 1 NC_012563.1 hypothetical protein 2681866 7765923 CLM_2666 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804817.1 2681387 R 536232 CDS YP_002804818.1 226949727 7766535 complement(2681868..2683238) 1 NC_012563.1 identified by match to protein family HMM PF00176; SNF2 domain-containing protein 2683238 7766535 CLM_2667 Clostridium botulinum A2 str. Kyoto SNF2 domain-containing protein YP_002804818.1 2681868 R 536232 CDS YP_002804819.1 226949728 7767226 complement(2683241..2683408) 1 NC_012563.1 hypothetical protein 2683408 7767226 CLM_2668 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804819.1 2683241 R 536232 CDS YP_002804820.1 226949729 7764374 complement(2683401..2683589) 1 NC_012563.1 VRR-NUC domain-containing protein 2683589 7764374 CLM_2669 Clostridium botulinum A2 str. Kyoto VRR-NUC domain-containing protein YP_002804820.1 2683401 R 536232 CDS YP_002804821.1 226949730 7767004 complement(2683948..2686371) 1 NC_012563.1 identified by match to protein family HMM PF05272; virulence-associated E domain-containing protein 2686371 7767004 CLM_2670 Clostridium botulinum A2 str. Kyoto virulence-associated E domain-containing protein YP_002804821.1 2683948 R 536232 CDS YP_002804822.1 226949731 7767749 complement(2686417..2687442) 1 NC_012563.1 hypothetical protein 2687442 7767749 CLM_2671 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804822.1 2686417 R 536232 CDS YP_002804823.1 226949732 7764741 complement(2687480..2687710) 1 NC_012563.1 glutamate racemase 2687710 7764741 CLM_2672 Clostridium botulinum A2 str. Kyoto glutamate racemase YP_002804823.1 2687480 R 536232 CDS YP_002804824.1 226949733 7765944 complement(2687749..2689716) 1 NC_012563.1 identified by match to protein family HMM PF00476; DNA polymerase 2689716 7765944 CLM_2673 Clostridium botulinum A2 str. Kyoto DNA polymerase YP_002804824.1 2687749 R 536232 CDS YP_002804825.1 226949734 7764553 complement(2689722..2690342) 1 NC_012563.1 phage-associated protein 2690342 7764553 CLM_2674 Clostridium botulinum A2 str. Kyoto phage-associated protein YP_002804825.1 2689722 R 536232 CDS YP_002804826.1 226949735 7767302 complement(2690354..2691499) 1 NC_012563.1 phage-associated protein 2691499 7767302 CLM_2675 Clostridium botulinum A2 str. Kyoto phage-associated protein YP_002804826.1 2690354 R 536232 CDS YP_002804827.1 226949736 7766195 complement(2691499..2691948) 1 NC_012563.1 hypothetical protein 2691948 7766195 CLM_2676 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804827.1 2691499 R 536232 CDS YP_002804828.1 226949737 7765485 complement(2691982..2692236) 1 NC_012563.1 hypothetical protein 2692236 7765485 CLM_2677 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804828.1 2691982 R 536232 CDS YP_002804829.1 226949738 7764463 complement(2692236..2692487) 1 NC_012563.1 hypothetical protein 2692487 7764463 CLM_2678 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804829.1 2692236 R 536232 CDS YP_002804830.1 226949739 7767949 complement(2692506..2692859) 1 NC_012563.1 hypothetical protein 2692859 7767949 CLM_2679 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804830.1 2692506 R 536232 CDS YP_002804831.1 226949740 7766860 complement(2692923..2693474) 1 NC_012563.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; sigma-70 family RNA polymerase sigma factor 2693474 7766860 CLM_2680 Clostridium botulinum A2 str. Kyoto sigma-70 family RNA polymerase sigma factor YP_002804831.1 2692923 R 536232 CDS YP_002804832.1 226949741 7764226 complement(2693679..2693837) 1 NC_012563.1 hypothetical protein 2693837 7764226 CLM_2681 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804832.1 2693679 R 536232 CDS YP_002804833.1 226949742 7765127 complement(2693850..2694623) 1 NC_012563.1 identified by match to protein family HMM PF09669; match to protein family HMM TIGR02681; Gp26 protein 2694623 7765127 CLM_2682 Clostridium botulinum A2 str. Kyoto Gp26 protein YP_002804833.1 2693850 R 536232 CDS YP_002804834.1 226949743 7766410 complement(2694684..2694827) 1 NC_012563.1 hypothetical protein 2694827 7766410 CLM_2683 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804834.1 2694684 R 536232 CDS YP_002804835.1 226949744 7766819 complement(2694928..2695128) 1 NC_012563.1 identified by match to protein family HMM PF01381; hypothetical protein 2695128 7766819 CLM_2684 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804835.1 2694928 R 536232 CDS YP_002804836.1 226949745 7766613 2695420..2695794 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 2695794 7766613 CLM_2685 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002804836.1 2695420 D 536232 CDS YP_002804837.1 226949746 7765283 2695798..2697336 1 NC_012563.1 identified by match to protein family HMM PF00239; resolvase family protein 2697336 7765283 CLM_2686 Clostridium botulinum A2 str. Kyoto resolvase family protein YP_002804837.1 2695798 D 536232 CDS YP_002804838.1 226949747 7767702 2697461..2698606 1 NC_012563.1 identified by match to protein family HMM PF01134; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2698606 7767702 CLM_2687 Clostridium botulinum A2 str. Kyoto tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002804838.1 2697461 D 536232 CDS YP_002804839.1 226949748 7767474 complement(2698657..2700087) 1 NC_012563.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 2700087 purB 7767474 purB Clostridium botulinum A2 str. Kyoto adenylosuccinate lyase YP_002804839.1 2698657 R 536232 CDS YP_002804840.1 226949749 7767135 2700325..2700546 1 NC_012563.1 identified by match to protein family HMM PF04070; hypothetical protein 2700546 7767135 CLM_2689 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804840.1 2700325 D 536232 CDS YP_002804841.1 226949750 7765675 complement(2700574..2700831) 1 NC_012563.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphocarrier protein HPr 2700831 ptsH 7765675 ptsH Clostridium botulinum A2 str. Kyoto phosphocarrier protein HPr YP_002804841.1 2700574 R 536232 CDS YP_002804842.1 226949751 7764414 complement(2700942..2702135) 1 NC_012563.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 2702135 aspB 7764414 aspB Clostridium botulinum A2 str. Kyoto aspartate aminotransferase YP_002804842.1 2700942 R 536232 CDS YP_002804843.1 226949752 7767922 complement(2702280..2702636) 1 NC_012563.1 identified by match to protein family HMM PF00893; multidrug resistance protein, SMR family 2702636 7767922 CLM_2692 Clostridium botulinum A2 str. Kyoto multidrug resistance protein, SMR family YP_002804843.1 2702280 R 536232 CDS YP_002804844.1 226949753 7767665 complement(2702633..2703916) 1 NC_012563.1 hypothetical protein 2703916 7767665 CLM_2693 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804844.1 2702633 R 536232 CDS YP_002804845.1 226949754 7764985 complement(2703935..2704801) 1 NC_012563.1 catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate; phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase 2704801 7764985 CLM_2694 Clostridium botulinum A2 str. Kyoto phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase YP_002804845.1 2703935 R 536232 CDS YP_002804846.1 226949755 7767818 complement(2704964..2705224) 1 NC_012563.1 identified by match to protein family HMM PF04232; stage V sporulation protein S 2705224 spoVS 7767818 spoVS Clostridium botulinum A2 str. Kyoto stage V sporulation protein S YP_002804846.1 2704964 R 536232 CDS YP_002804847.1 226949756 7766708 complement(2705363..2706904) 1 NC_012563.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 2706904 7766708 CLM_2696 Clostridium botulinum A2 str. Kyoto phosphodiesterase YP_002804847.1 2705363 R 536232 CDS YP_002804848.1 226949757 7765803 complement(2707139..2708206) 1 NC_012563.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2708206 recA 7765803 recA Clostridium botulinum A2 str. Kyoto recombinase A YP_002804848.1 2707139 R 536232 CDS YP_002804849.1 226949758 7765134 complement(2708345..2708929) 1 NC_012563.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2708929 pgsA 7765134 pgsA Clostridium botulinum A2 str. Kyoto CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002804849.1 2708345 R 536232 CDS YP_002804850.1 226949759 7765153 complement(2708913..2710250) 1 NC_012563.1 identified by match to protein family HMM PF00919; match to protein family HMM PF01938; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01125; RNA modification enzyme, MiaB family 2710250 7765153 CLM_2699 Clostridium botulinum A2 str. Kyoto RNA modification enzyme, MiaB family YP_002804850.1 2708913 R 536232 CDS YP_002804851.1 226949760 7767230 complement(2710345..2712621) 1 NC_012563.1 identified by match to protein family HMM PF01580; match to protein family HMM PF09397; DNA translocase FtsK/SpoIIIE 2712621 ftsK 7767230 ftsK Clostridium botulinum A2 str. Kyoto DNA translocase FtsK/SpoIIIE YP_002804851.1 2710345 R 536232 CDS YP_002804852.1 226949761 7766333 complement(2713102..2713794) 1 NC_012563.1 identified by match to protein family HMM PF00574; Clp protease family protein 2713794 7766333 CLM_2701 Clostridium botulinum A2 str. Kyoto Clp protease family protein YP_002804852.1 2713102 R 536232 CDS YP_002804853.1 226949762 7765427 complement(2714042..2715247) 1 NC_012563.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive; aspartate kinase I 2715247 dapG 7765427 dapG Clostridium botulinum A2 str. Kyoto aspartate kinase I YP_002804853.1 2714042 R 536232 CDS YP_002804854.1 226949763 7765436 complement(2715263..2715535) 1 NC_012563.1 identified by match to protein family HMM PF05239; match to protein family HMM TIGR02888; PRC-barrel domain-containing protein 2715535 7765436 CLM_2703 Clostridium botulinum A2 str. Kyoto PRC-barrel domain-containing protein YP_002804854.1 2715263 R 536232 CDS YP_002804855.1 226949764 7766439 complement(2715612..2716913) 1 NC_012563.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16 family 2716913 7766439 CLM_2704 Clostridium botulinum A2 str. Kyoto peptidase, M16 family YP_002804855.1 2715612 R 536232 CDS YP_002804856.1 226949765 7766006 complement(2717087..2719195) 1 NC_012563.1 identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; match to protein family HMM TIGR03591; polynucleotide phosphorylase/polyadenylase 2719195 pnpA 7766006 pnpA Clostridium botulinum A2 str. Kyoto polynucleotide phosphorylase/polyadenylase YP_002804856.1 2717087 R 536232 CDS YP_002804857.1 226949766 7766382 complement(2719459..2719773) 1 NC_012563.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 2719773 rpsO 7766382 rpsO Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S15 YP_002804857.1 2719459 R 536232 CDS YP_002804858.1 226949767 7767195 complement(2719855..2720775) 1 NC_012563.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 2720775 ribF 7767195 ribF Clostridium botulinum A2 str. Kyoto bifunctional riboflavin kinase/FMN adenylyltransferase YP_002804858.1 2719855 R 536232 CDS YP_002804859.1 226949768 7764660 complement(2720788..2721657) 1 NC_012563.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 2721657 truB 7764660 truB Clostridium botulinum A2 str. Kyoto tRNA pseudouridine synthase B YP_002804859.1 2720788 R 536232 CDS YP_002804860.1 226949769 7764643 complement(2721658..2722620) 1 NC_012563.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH family protein 2722620 7764643 CLM_2709 Clostridium botulinum A2 str. Kyoto DHH family protein YP_002804860.1 2721658 R 536232 CDS YP_002804861.1 226949770 7765465 complement(2722610..2722972) 1 NC_012563.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 2722972 rbfA 7765465 rbfA Clostridium botulinum A2 str. Kyoto ribosome-binding factor A YP_002804861.1 2722610 R 536232 CDS YP_002804862.1 226949771 7767967 complement(2723003..2725069) 1 NC_012563.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 2725069 infB 7767967 infB Clostridium botulinum A2 str. Kyoto translation initiation factor IF-2 YP_002804862.1 2723003 R 536232 CDS YP_002804863.1 226949772 7765115 complement(2725087..2725404) 1 NC_012563.1 identified by match to protein family HMM PF01248; ribosomal protein L7Ae family protein 2725404 7765115 CLM_2712 Clostridium botulinum A2 str. Kyoto ribosomal protein L7Ae family protein YP_002804863.1 2725087 R 536232 CDS YP_002804864.1 226949773 7767087 complement(2725391..2725663) 1 NC_012563.1 identified by match to protein family HMM PF04296; hypothetical protein 2725663 7767087 CLM_2713 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804864.1 2725391 R 536232 CDS YP_002804865.1 226949774 7766037 complement(2725722..2727095) 1 NC_012563.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 2727095 nusA 7766037 nusA Clostridium botulinum A2 str. Kyoto transcription elongation factor NusA YP_002804865.1 2725722 R 536232 CDS YP_002804866.1 226949775 7767424 complement(2727112..2727573) 1 NC_012563.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 2727573 7767424 CLM_2715 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804866.1 2727112 R 536232 CDS YP_002804867.1 226949776 7767819 complement(2727878..2732176) 1 NC_012563.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 2732176 polC 7767819 polC Clostridium botulinum A2 str. Kyoto DNA polymerase III PolC YP_002804867.1 2727878 R 536232 CDS YP_002804868.1 226949777 7764727 complement(2732455..2733504) 1 NC_012563.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2733504 ispG 7764727 ispG Clostridium botulinum A2 str. Kyoto 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002804868.1 2732455 R 536232 CDS YP_002804869.1 226949778 7766009 complement(2733645..2734655) 1 NC_012563.1 identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054; RIP metalloprotease RseP 2734655 rseP 7766009 rseP Clostridium botulinum A2 str. Kyoto RIP metalloprotease RseP YP_002804869.1 2733645 R 536232 CDS YP_002804870.1 226949779 7767913 complement(2734700..2735857) 1 NC_012563.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2735857 dxr 7767913 dxr Clostridium botulinum A2 str. Kyoto 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002804870.1 2734700 R 536232 CDS YP_002804871.1 226949780 7764342 complement(2735894..2736874) 1 NC_012563.1 hypothetical protein 2736874 7764342 CLM_2720 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804871.1 2735894 R 536232 CDS YP_002804872.1 226949781 7765282 complement(2736974..2737096) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2737096 7765282 CLM_2721 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804872.1 2736974 R 536232 CDS YP_002804873.1 226949782 7766583 complement(2737155..2737343) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2737343 7766583 CLM_2722 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804873.1 2737155 R 536232 CDS YP_002804874.1 226949783 7767803 complement(2737528..2738325) 1 NC_012563.1 identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase 2738325 cdsA 7767803 cdsA Clostridium botulinum A2 str. Kyoto phosphatidate cytidylyltransferase YP_002804874.1 2737528 R 536232 CDS YP_002804875.1 226949784 7766989 complement(2738350..2739108) 1 NC_012563.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 2739108 uppS 7766989 uppS Clostridium botulinum A2 str. Kyoto UDP pyrophosphate synthase YP_002804875.1 2738350 R 536232 CDS YP_002804876.1 226949785 7765790 complement(2739174..2739728) 1 NC_012563.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 2739728 frr 7765790 frr Clostridium botulinum A2 str. Kyoto ribosome recycling factor YP_002804876.1 2739174 R 536232 CDS YP_002804877.1 226949786 7765148 complement(2739744..2740460) 1 NC_012563.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 2740460 pyrH 7765148 pyrH Clostridium botulinum A2 str. Kyoto uridylate kinase YP_002804877.1 2739744 R 536232 CDS YP_002804878.1 226949787 7767555 complement(2740835..2741758) 1 NC_012563.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2741758 tsf 7767555 tsf Clostridium botulinum A2 str. Kyoto elongation factor Ts YP_002804878.1 2740835 R 536232 CDS YP_002804879.1 226949788 7766435 complement(2741846..2742547) 1 NC_012563.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2742547 rpsB 7766435 rpsB Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S2 YP_002804879.1 2741846 R 536232 CDS YP_002804880.1 226949789 7765911 complement(2742784..2743560) 1 NC_012563.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 2743560 codY 7765911 codY Clostridium botulinum A2 str. Kyoto transcriptional repressor CodY YP_002804880.1 2742784 R 536232 CDS YP_002804881.1 226949790 7765044 complement(2743767..2745857) 1 NC_012563.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 2745857 topA 7765044 topA Clostridium botulinum A2 str. Kyoto DNA topoisomerase I YP_002804881.1 2743767 R 536232 CDS YP_002804882.1 226949791 7764244 complement(2746241..2747326) 1 NC_012563.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA protecting protein DprA 2747326 dprA 7764244 dprA Clostridium botulinum A2 str. Kyoto DNA protecting protein DprA YP_002804882.1 2746241 R 536232 CDS YP_002804883.1 226949792 7767260 2747526..2749049 1 NC_012563.1 identified by match to protein family HMM PF01078; match to protein family HMM PF07728; match to protein family HMM TIGR00368; putative Mg chelatase 2749049 7767260 CLM_2732 Clostridium botulinum A2 str. Kyoto putative Mg chelatase YP_002804883.1 2747526 D 536232 CDS YP_002804884.1 226949793 7766943 2749065..2749436 1 NC_012563.1 identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252; hypothetical protein 2749436 7766943 CLM_2733 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804884.1 2749065 D 536232 CDS YP_002804885.1 226949794 7764711 complement(2749519..2750328) 1 NC_012563.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 2750328 rnhB 7764711 rnhB Clostridium botulinum A2 str. Kyoto ribonuclease HII YP_002804885.1 2749519 R 536232 CDS YP_002804886.1 226949795 7766433 complement(2750625..2751503) 1 NC_012563.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 2751503 rbgA 7766433 rbgA Clostridium botulinum A2 str. Kyoto ribosomal biogenesis GTPase YP_002804886.1 2750625 R 536232 CDS YP_002804887.1 226949796 7767547 complement(2751808..2752332) 1 NC_012563.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase I 2752332 lepB 7767547 lepB Clostridium botulinum A2 str. Kyoto signal peptidase I YP_002804887.1 2751808 R 536232 CDS YP_002804888.1 226949797 7768073 complement(2752391..2752735) 1 NC_012563.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 2752735 rplS 7768073 rplS Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L19 YP_002804888.1 2752391 R 536232 CDS YP_002804889.1 226949798 7765377 complement(2752886..2753608) 1 NC_012563.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 2753608 trmD 7765377 trmD Clostridium botulinum A2 str. Kyoto tRNA (guanine-N(1)-)-methyltransferase YP_002804889.1 2752886 R 536232 CDS YP_002804890.1 226949799 7767486 complement(2753599..2754093) 1 NC_012563.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 2754093 rimM 7767486 rimM Clostridium botulinum A2 str. Kyoto 16S rRNA-processing protein RimM YP_002804890.1 2753599 R 536232 CDS YP_002804891.1 226949800 7766561 complement(2754206..2754433) 1 NC_012563.1 hypothetical protein 2754433 7766561 CLM_2740 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804891.1 2754206 R 536232 CDS YP_002804892.1 226949801 7765229 complement(2754454..2754702) 1 NC_012563.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 2754702 rpsP 7765229 rpsP Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S16 YP_002804892.1 2754454 R 536232 CDS YP_002804893.1 226949802 7764363 complement(2754733..2756082) 1 NC_012563.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein 2756082 ffh 7764363 ffh Clostridium botulinum A2 str. Kyoto signal recognition particle protein YP_002804893.1 2754733 R 536232 CDS YP_002804894.1 226949803 7764935 complement(2756095..2756427) 1 NC_012563.1 identified by match to protein family HMM PF04297; putative DNA-binding protein 2756427 7764935 CLM_2743 Clostridium botulinum A2 str. Kyoto putative DNA-binding protein YP_002804894.1 2756095 R 536232 CDS YP_002804895.1 226949804 7765452 complement(2756651..2757562) 1 NC_012563.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; signal recognition particle-docking protein FtsY 2757562 ftsY 7765452 ftsY Clostridium botulinum A2 str. Kyoto signal recognition particle-docking protein FtsY YP_002804895.1 2756651 R 536232 CDS YP_002804896.1 226949805 7766824 complement(2757725..2761306) 1 NC_012563.1 identified by match to protein family HMM PF02463; match to protein family HMM PF06470; match to protein family HMM TIGR02168; chromosome segregation protein SMC 2761306 smc 7766824 smc Clostridium botulinum A2 str. Kyoto chromosome segregation protein SMC YP_002804896.1 2757725 R 536232 CDS YP_002804897.1 226949806 7767588 complement(2761319..2761447) 1 NC_012563.1 hypothetical protein 2761447 7767588 CLM_2746 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804897.1 2761319 R 536232 CDS YP_002804898.1 226949807 7765129 complement(2761570..2762661) 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 2762661 7765129 CLM_2747 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002804898.1 2761570 R 536232 CDS YP_002804899.1 226949808 7766015 complement(2762654..2763358) 1 NC_012563.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 2763358 rnc 7766015 rnc Clostridium botulinum A2 str. Kyoto ribonuclease III YP_002804899.1 2762654 R 536232 CDS YP_002804900.1 226949809 7765321 complement(2763483..2763716) 1 NC_012563.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 2763716 acpP 7765321 acpP Clostridium botulinum A2 str. Kyoto acyl carrier protein YP_002804900.1 2763483 R 536232 CDS YP_002804901.1 226949810 7766193 complement(2763794..2764801) 1 NC_012563.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 2764801 plsX 7766193 plsX Clostridium botulinum A2 str. Kyoto putative glycerol-3-phosphate acyltransferase PlsX YP_002804901.1 2763794 R 536232 CDS YP_002804902.1 226949811 7767812 complement(2764891..2765073) 1 NC_012563.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2765073 rpmF 7767812 rpmF Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L32 YP_002804902.1 2764891 R 536232 CDS YP_002804903.1 226949812 7764676 complement(2765087..2765587) 1 NC_012563.1 identified by match to protein family HMM PF02620; hypothetical protein 2765587 7764676 CLM_2752 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804903.1 2765087 R 536232 CDS YP_002804904.1 226949813 7766089 complement(2765705..2766898) 1 NC_012563.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2766898 ackA 7766089 ackA Clostridium botulinum A2 str. Kyoto acetate kinase YP_002804904.1 2765705 R 536232 CDS YP_002804905.1 226949814 7764349 complement(2767038..2768036) 1 NC_012563.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 2768036 eutD 7764349 eutD Clostridium botulinum A2 str. Kyoto phosphotransacetylase YP_002804905.1 2767038 R 536232 CDS YP_002804906.1 226949815 7767048 complement(2768371..2769249) 1 NC_012563.1 hypothetical protein 2769249 7767048 CLM_2755 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804906.1 2768371 R 536232 CDS YP_002804907.1 226949816 7766182 complement(2769616..2770335) 1 NC_012563.1 Selenoprotein. identified by similarity to GB:CAB38127.2; D-proline reductase subunit gamma PrdB 2770335 prdB 7766182 prdB Clostridium botulinum A2 str. Kyoto D-proline reductase subunit gamma PrdB YP_002804907.1 2769616 R 536232 CDS YP_002804908.1 226949817 7767834 complement(2770365..2770640) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2770640 7767834 CLM_2758 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804908.1 2770365 R 536232 CDS YP_002804909.1 226949818 7767660 complement(2770649..2772763) 1 NC_012563.1 identified by similarity to GB:CAB38126.1; D-proline reductase, PrdA proprotein 2772763 prdA 7767660 prdA Clostridium botulinum A2 str. Kyoto D-proline reductase, PrdA proprotein YP_002804909.1 2770649 R 536232 CDS YP_002804910.1 226949819 7766809 complement(2772796..2772966) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer; putative; hypothetical protein 2772966 7766809 CLM_2760 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804910.1 2772796 R 536232 CDS YP_002804911.1 226949820 7765915 complement(2772988..2774106) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01512; putative electron transport protein 2774106 7765915 CLM_2761 Clostridium botulinum A2 str. Kyoto putative electron transport protein YP_002804911.1 2772988 R 536232 CDS YP_002804912.1 226949821 7765091 complement(2775103..2775999) 1 NC_012563.1 hypothetical protein 2775999 7765091 CLM_2762 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804912.1 2775103 R 536232 CDS YP_002804913.1 226949822 7764243 complement(2776309..2778327) 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 2778327 7764243 CLM_2763 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002804913.1 2776309 R 536232 CDS YP_002804914.1 226949823 7765888 complement(2779347..2780432) 1 NC_012563.1 hypothetical protein 2780432 7765888 CLM_2766 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804914.1 2779347 R 536232 CDS YP_002804915.1 226949824 7764928 complement(2780509..2781585) 1 NC_012563.1 hypothetical protein 2781585 7764928 CLM_2767 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804915.1 2780509 R 536232 CDS YP_002804916.1 226949825 7768079 2782140..2783585 1 NC_012563.1 identified by match to protein family HMM PF00324; amino acid permease family protein 2783585 7768079 CLM_2768 Clostridium botulinum A2 str. Kyoto amino acid permease family protein YP_002804916.1 2782140 D 536232 CDS YP_002804917.1 226949826 7766192 complement(2783723..2784610) 1 NC_012563.1 hypothetical protein 2784610 7766192 CLM_2769 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804917.1 2783723 R 536232 CDS YP_002804918.1 226949827 7765484 complement(2785140..2786147) 1 NC_012563.1 identified by match to protein family HMM PF05544; proline racemase 2786147 7765484 CLM_2770 Clostridium botulinum A2 str. Kyoto proline racemase YP_002804918.1 2785140 R 536232 CDS YP_002804919.1 226949828 7766762 complement(2787762..2788487) 1 NC_012563.1 Selenoprotein. identified by similarity to GB:CAB38127.2; D-proline reductase subunit gamma PrdB 2788487 7766762 CLM_2774 Clostridium botulinum A2 str. Kyoto D-proline reductase subunit gamma PrdB YP_002804919.1 2787762 R 536232 CDS YP_002804920.1 226949829 7767222 complement(2788563..2788838) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2788838 7767222 CLM_2775 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804920.1 2788563 R 536232 CDS YP_002804921.1 226949830 7767881 complement(2788847..2790955) 1 NC_012563.1 identified by similarity to GB:CAB38126.1; match to protein family HMM PF09338; D-proline reductase, PrdA proprotein 2790955 prdA 7767881 prdA Clostridium botulinum A2 str. Kyoto D-proline reductase, PrdA proprotein YP_002804921.1 2788847 R 536232 CDS YP_002804922.1 226949831 7766552 complement(2790980..2791156) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer; putative; hypothetical protein 2791156 7766552 CLM_2777 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804922.1 2790980 R 536232 CDS YP_002804923.1 226949832 7766105 complement(2791178..2792296) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01512; putative electron transport protein 2792296 7766105 CLM_2778 Clostridium botulinum A2 str. Kyoto putative electron transport protein YP_002804923.1 2791178 R 536232 CDS YP_002804924.1 226949833 7764773 complement(2792937..2793599) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2793599 7764773 CLM_2779 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804924.1 2792937 R 536232 CDS YP_002804925.1 226949834 7765094 complement(2793639..2794943) 1 NC_012563.1 identified by match to protein family HMM PF01512; putative electron transport protein 2794943 7765094 CLM_2780 Clostridium botulinum A2 str. Kyoto putative electron transport protein YP_002804925.1 2793639 R 536232 CDS YP_002804926.1 226949835 7768024 2794942..2795058 1 NC_012563.1 hypothetical protein 2795058 7768024 CLM_2781 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804926.1 2794942 D 536232 CDS YP_002804928.1 226949837 7766312 complement(2795536..2796063) 1 NC_012563.1 hypothetical protein 2796063 7766312 CLM_2783 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804928.1 2795536 R 536232 CDS YP_002804929.1 226949838 7764392 complement(2796068..2796547) 1 NC_012563.1 hypothetical protein 2796547 7764392 CLM_2784 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804929.1 2796068 R 536232 CDS YP_002804930.1 226949839 7764396 complement(2796763..2796942) 1 NC_012563.1 transposase 2796942 7764396 CLM_2786 Clostridium botulinum A2 str. Kyoto transposase YP_002804930.1 2796763 R 536232 CDS YP_002804931.1 226949840 7766181 complement(2797038..2797466) 1 NC_012563.1 PrdA domain-containing protein 2797466 7766181 CLM_2787 Clostridium botulinum A2 str. Kyoto PrdA domain-containing protein YP_002804931.1 2797038 R 536232 CDS YP_002804932.1 226949841 7767324 complement(2797497..2798807) 1 NC_012563.1 identified by match to protein family HMM PF01512; putative electron transport protein 2798807 7767324 CLM_2788 Clostridium botulinum A2 str. Kyoto putative electron transport protein YP_002804932.1 2797497 R 536232 CDS YP_002804933.1 226949842 7765938 complement(2798983..2800737) 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00571; match to protein family HMM PF00989; match to protein family HMM PF02954; match to protein family HMM PF08448; match to protein family HMM TIGR00229; sensory box sigma-54 dependent transcriptional regulator 2800737 7765938 CLM_2789 Clostridium botulinum A2 str. Kyoto sensory box sigma-54 dependent transcriptional regulator YP_002804933.1 2798983 R 536232 CDS YP_002804934.1 226949843 7765072 2801073..2802302 1 NC_012563.1 identified by match to protein family HMM PF05636; hypothetical protein 2802302 7765072 CLM_2790 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804934.1 2801073 D 536232 CDS YP_002804935.1 226949844 7767779 2802362..2803528 1 NC_012563.1 identified by match to protein family HMM PF07670; match to protein family HMM TIGR02871; nucleoside recognition domain-containing protein 2803528 7767779 CLM_2791 Clostridium botulinum A2 str. Kyoto nucleoside recognition domain-containing protein YP_002804935.1 2802362 D 536232 CDS YP_002804936.1 226949845 7766984 complement(2803529..2804053) 1 NC_012563.1 hypothetical protein 2804053 7766984 CLM_2792 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804936.1 2803529 R 536232 CDS YP_002804937.1 226949846 7766201 complement(2804066..2804560) 1 NC_012563.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 2804560 coaD 7766201 coaD Clostridium botulinum A2 str. Kyoto phosphopantetheine adenylyltransferase YP_002804937.1 2804066 R 536232 CDS YP_002804938.1 226949847 7765948 complement(2804562..2805119) 1 NC_012563.1 identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095; putative methyltransferase 2805119 7765948 CLM_2794 Clostridium botulinum A2 str. Kyoto putative methyltransferase YP_002804938.1 2804562 R 536232 CDS YP_002804939.1 226949848 7764486 complement(2805381..2807420) 1 NC_012563.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 2807420 recG 7764486 recG Clostridium botulinum A2 str. Kyoto ATP-dependent DNA helicase RecG YP_002804939.1 2805381 R 536232 CDS YP_002804940.1 226949849 7765010 complement(2807770..2809395) 1 NC_012563.1 identified by match to protein family HMM PF02734; match to protein family HMM TIGR03599; DAK2 domain-containing protein 2809395 7765010 CLM_2796 Clostridium botulinum A2 str. Kyoto DAK2 domain-containing protein YP_002804940.1 2807770 R 536232 CDS YP_002804941.1 226949850 7767853 complement(2809410..2809760) 1 NC_012563.1 identified by match to protein family HMM PF03780; hypothetical protein 2809760 7767853 CLM_2797 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804941.1 2809410 R 536232 CDS YP_002804942.1 226949851 7765600 2809960..2810151 1 NC_012563.1 required for 70S ribosome assembly; 50S ribosomal protein L28 2810151 rpmB 7765600 rpmB Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L28 YP_002804942.1 2809960 D 536232 CDS YP_002804943.1 226949852 7764451 complement(2810200..2810319) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2810319 7764451 CLM_2799 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804943.1 2810200 R 536232 CDS YP_002804944.1 226949853 7764472 complement(2810397..2810552) 1 NC_012563.1 hypothetical protein 2810552 7764472 CLM_2800 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804944.1 2810397 R 536232 CDS YP_002804945.1 226949854 7767526 complement(2810981..2811625) 1 NC_012563.1 identified by match to protein family HMM PF04263; match to protein family HMM TIGR01378; thiamine diphosphokinase 2811625 7767526 CLM_2801 Clostridium botulinum A2 str. Kyoto thiamine diphosphokinase YP_002804945.1 2810981 R 536232 CDS YP_002804946.1 226949855 7767126 complement(2811627..2812277) 1 NC_012563.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 2812277 rpe 7767126 rpe Clostridium botulinum A2 str. Kyoto ribulose-phosphate 3-epimerase YP_002804946.1 2811627 R 536232 CDS YP_002804947.1 226949856 7766066 complement(2812271..2813149) 1 NC_012563.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 2813149 rsgA 7766066 rsgA Clostridium botulinum A2 str. Kyoto ribosome-associated GTPase YP_002804947.1 2812271 R 536232 CDS YP_002804948.1 226949857 7766593 complement(2813356..2815320) 1 NC_012563.1 identified by match to protein family HMM PF00069; match to protein family HMM PF03793; match to protein family HMM PF07714; histidine kinase 2815320 7766593 CLM_2804 Clostridium botulinum A2 str. Kyoto histidine kinase YP_002804948.1 2813356 R 536232 CDS YP_002804949.1 226949858 7766699 complement(2815298..2816047) 1 NC_012563.1 identified by match to protein family HMM PF00481; protein phosphatase family protein 2816047 7766699 CLM_2805 Clostridium botulinum A2 str. Kyoto protein phosphatase family protein YP_002804949.1 2815298 R 536232 CDS YP_002804950.1 226949859 7764784 complement(2816066..2817094) 1 NC_012563.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 2817094 7764784 CLM_2806 Clostridium botulinum A2 str. Kyoto ribosomal RNA large subunit methyltransferase N YP_002804950.1 2816066 R 536232 CDS YP_002804951.1 226949860 7766129 complement(2817106..2818434) 1 NC_012563.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563; ribosomal RNA small subunit methyltransferase B 2818434 sun 7766129 sun Clostridium botulinum A2 str. Kyoto ribosomal RNA small subunit methyltransferase B YP_002804951.1 2817106 R 536232 CDS YP_002804952.1 226949861 7766999 complement(2818455..2819171) 1 NC_012563.1 identified by match to protein family HMM PF04298; putative neutral zinc metallopeptidase 2819171 7766999 CLM_2808 Clostridium botulinum A2 str. Kyoto putative neutral zinc metallopeptidase YP_002804952.1 2818455 R 536232 CDS YP_002804953.1 226949862 7766316 complement(2819489..2820430) 1 NC_012563.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 2820430 fmt 7766316 fmt Clostridium botulinum A2 str. Kyoto methionyl-tRNA formyltransferase YP_002804953.1 2819489 R 536232 CDS YP_002804954.1 226949863 7767344 complement(2820447..2820890) 1 NC_012563.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 2820890 def 7767344 def Clostridium botulinum A2 str. Kyoto peptide deformylase YP_002804954.1 2820447 R 536232 CDS YP_002804955.1 226949864 7765964 complement(2820918..2823125) 1 NC_012563.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 2823125 priA 7765964 priA Clostridium botulinum A2 str. Kyoto primosome assembly protein PriA YP_002804955.1 2820918 R 536232 CDS YP_002804956.1 226949865 7766677 complement(2823514..2824701) 1 NC_012563.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 2824701 coaBC 7766677 coaBC Clostridium botulinum A2 str. Kyoto bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_002804956.1 2823514 R 536232 CDS YP_002804957.1 226949866 7767822 complement(2824703..2824921) 1 NC_012563.1 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 2824921 rpoZ 7767822 rpoZ Clostridium botulinum A2 str. Kyoto DNA-directed RNA polymerase subunit omega YP_002804957.1 2824703 R 536232 CDS YP_002804958.1 226949867 7764503 complement(2824902..2825531) 1 NC_012563.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 2825531 gmk 7764503 gmk Clostridium botulinum A2 str. Kyoto guanylate kinase YP_002804958.1 2824902 R 536232 CDS YP_002804959.1 226949868 7765329 complement(2825531..2825806) 1 NC_012563.1 identified by match to protein family HMM PF04025; hypothetical protein 2825806 7765329 CLM_2815 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804959.1 2825531 R 536232 CDS YP_002804960.1 226949869 7766422 complement(2825822..2826700) 1 NC_012563.1 identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255; hypothetical protein 2826700 7766422 CLM_2816 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804960.1 2825822 R 536232 CDS YP_002804961.1 226949870 7766834 complement(2826894..2827895) 1 NC_012563.1 identified by match to protein family HMM PF00710; L-asparaginase 2827895 ansA 7766834 ansA Clostridium botulinum A2 str. Kyoto L-asparaginase YP_002804961.1 2826894 R 536232 CDS YP_002804962.1 226949871 7764208 2828446..2828607 1 NC_012563.1 hypothetical protein 2828607 7764208 CLM_2818 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804962.1 2828446 D 536232 CDS YP_002804963.1 226949872 7767274 complement(2829317..2830798) 1 NC_012563.1 identified by match to protein family HMM PF09547; match to protein family HMM TIGR02836; stage IV sporulation protein A 2830798 spoIVA 7767274 spoIVA Clostridium botulinum A2 str. Kyoto stage IV sporulation protein A YP_002804963.1 2829317 R 536232 CDS YP_002804964.1 226949873 7764570 2831389..2831565 1 NC_012563.1 hypothetical protein 2831565 7764570 CLM_2822 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804964.1 2831389 D 536232 CDS YP_002804965.1 226949874 7766285 complement(2831635..2832633) 1 NC_012563.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2832633 gpsA 7766285 gpsA Clostridium botulinum A2 str. Kyoto NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002804965.1 2831635 R 536232 CDS YP_002804966.1 226949875 7765926 complement(2832804..2834123) 1 NC_012563.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2834123 engA 7765926 engA Clostridium botulinum A2 str. Kyoto GTP-binding protein EngA YP_002804966.1 2832804 R 536232 CDS YP_002804967.1 226949876 7765089 complement(2834126..2835490) 1 NC_012563.1 identified by match to protein family HMM PF04459; hypothetical protein 2835490 7765089 CLM_2825 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804967.1 2834126 R 536232 CDS YP_002804968.1 226949877 7767678 complement(2835912..2836565) 1 NC_012563.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 2836565 phoU 7767678 phoU Clostridium botulinum A2 str. Kyoto phosphate transport system regulatory protein PhoU YP_002804968.1 2835912 R 536232 CDS YP_002804969.1 226949878 7764532 complement(2836595..2837344) 1 NC_012563.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 2837344 pstB 7764532 pstB Clostridium botulinum A2 str. Kyoto phosphate transporter ATP-binding protein YP_002804969.1 2836595 R 536232 CDS YP_002804970.1 226949879 7767826 complement(2837357..2838241) 1 NC_012563.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 2838241 pstA 7767826 pstA Clostridium botulinum A2 str. Kyoto phosphate ABC transporter permease YP_002804970.1 2837357 R 536232 CDS YP_002804971.1 226949880 7766882 complement(2838241..2839164) 1 NC_012563.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 2839164 pstC 7766882 pstC Clostridium botulinum A2 str. Kyoto phosphate ABC transporter permease YP_002804971.1 2838241 R 536232 CDS YP_002804972.1 226949881 7765501 complement(2839371..2840243) 1 NC_012563.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136; phosphate ABC transporter substrate-binding protein 2840243 pstS 7765501 pstS Clostridium botulinum A2 str. Kyoto phosphate ABC transporter substrate-binding protein YP_002804972.1 2839371 R 536232 CDS YP_002804973.1 226949882 7766526 complement(2840490..2842199) 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensor histidine kinase 2842199 7766526 CLM_2831 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002804973.1 2840490 R 536232 CDS YP_002804974.1 226949883 7765894 complement(2842211..2842909) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; putative phosphate regulon DNA-binding response regulator 2842909 7765894 CLM_2832 Clostridium botulinum A2 str. Kyoto putative phosphate regulon DNA-binding response regulator YP_002804974.1 2842211 R 536232 CDS YP_002804975.1 226949884 7764223 complement(2842920..2843639) 1 NC_012563.1 identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein 2843639 7764223 CLM_2833 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804975.1 2842920 R 536232 CDS YP_002804976.1 226949885 7767562 complement(2844037..2844492) 1 NC_012563.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 2844492 nrdR 7767562 nrdR Clostridium botulinum A2 str. Kyoto transcriptional regulator NrdR YP_002804976.1 2844037 R 536232 CDS YP_002804977.1 226949886 7765901 complement(2844623..2844886) 1 NC_012563.1 identified by match to protein family HMM PF05239; match to protein family HMM TIGR02888; PRC-barrel domain-containing protein 2844886 7765901 CLM_2835 Clostridium botulinum A2 str. Kyoto PRC-barrel domain-containing protein YP_002804977.1 2844623 R 536232 CDS YP_002804978.1 226949887 7765333 complement(2845035..2845808) 1 NC_012563.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin; sporulation sigma factor SigG 2845808 sigG 7765333 sigG Clostridium botulinum A2 str. Kyoto sporulation sigma factor SigG YP_002804978.1 2845035 R 536232 CDS YP_002804979.1 226949888 7765613 complement(2845883..2846590) 1 NC_012563.1 sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation; sporulation sigma factor SigE 2846590 sigE 7765613 sigE Clostridium botulinum A2 str. Kyoto sporulation sigma factor SigE YP_002804979.1 2845883 R 536232 CDS YP_002804980.1 226949889 7766566 complement(2846602..2847399) 1 NC_012563.1 identified by match to protein family HMM PF03419; match to protein family HMM TIGR02854; sporulation factor SpoIIGA 2847399 spoIIGA 7766566 spoIIGA Clostridium botulinum A2 str. Kyoto sporulation factor SpoIIGA YP_002804980.1 2846602 R 536232 CDS YP_002804981.1 226949890 7765218 complement(2847712..2848821) 1 NC_012563.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 2848821 ftsZ 7765218 ftsZ Clostridium botulinum A2 str. Kyoto cell division protein FtsZ YP_002804981.1 2847712 R 536232 CDS YP_002804982.1 226949891 7764515 complement(2848844..2850097) 1 NC_012563.1 identified by match to protein family HMM PF02491; match to protein family HMM TIGR01174; cell division protein FtsA 2850097 ftsA 7764515 ftsA Clostridium botulinum A2 str. Kyoto cell division protein FtsA YP_002804982.1 2848844 R 536232 CDS YP_002804983.1 226949892 7767842 complement(2850254..2851528) 1 NC_012563.1 identified by match to protein family HMM PF00535; group 2 family glycosyl transferase 2851528 7767842 CLM_2841 Clostridium botulinum A2 str. Kyoto group 2 family glycosyl transferase YP_002804983.1 2850254 R 536232 CDS YP_002804984.1 226949893 7767108 2851966..2852109 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2852109 7767108 CLM_2842 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804984.1 2851966 D 536232 CDS YP_002804985.1 226949894 7765724 complement(2852187..2853239) 1 NC_012563.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420; twitching motility protein 2853239 pilT 7765724 pilT Clostridium botulinum A2 str. Kyoto twitching motility protein YP_002804985.1 2852187 R 536232 CDS YP_002804986.1 226949895 7767635 complement(2853241..2854017) 1 NC_012563.1 identified by match to protein family HMM PF01488; match to protein family HMM PF08501; shikimate dehydrogenase 2854017 aroE 7767635 aroE Clostridium botulinum A2 str. Kyoto shikimate dehydrogenase YP_002804986.1 2853241 R 536232 CDS YP_002804987.1 226949896 7766508 complement(2854149..2854853) 1 NC_012563.1 sigma-28; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell after engulfment; sporulation sigma factor SigK 2854853 sigK 7766508 sigK Clostridium botulinum A2 str. Kyoto sporulation sigma factor SigK YP_002804987.1 2854149 R 536232 CDS YP_002804988.1 226949897 7767624 complement(2855279..2855458) 1 NC_012563.1 hypothetical protein 2855458 7767624 CLM_2846 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804988.1 2855279 R 536232 CDS YP_002804989.1 226949898 7766387 complement(2855903..2856040) 1 NC_012563.1 hypothetical protein 2856040 7766387 CLM_2847 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804989.1 2855903 R 536232 CDS YP_002804990.1 226949899 7765682 complement(2856892..2857065) 1 NC_012563.1 identified by similarity to GB:ABR33837.1; hypothetical protein 2857065 7765682 CLM_2848 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804990.1 2856892 R 536232 CDS YP_002804991.1 226949900 7767061 2857241..2857423 1 NC_012563.1 hypothetical protein 2857423 7767061 CLM_2849 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804991.1 2857241 D 536232 CDS YP_002804992.1 226949901 7767906 complement(2857777..2858445) 1 NC_012563.1 identified by match to protein family HMM PF09557; match to protein family HMM TIGR02271; hypothetical protein 2858445 7767906 CLM_2850 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804992.1 2857777 R 536232 CDS YP_002804993.1 226949902 7767591 complement(2858524..2859000) 1 NC_012563.1 identified by match to protein family HMM PF09557; match to protein family HMM TIGR02271; hypothetical protein 2859000 7767591 CLM_2851 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804993.1 2858524 R 536232 CDS YP_002804994.1 226949903 7764593 complement(2859127..2859327) 1 NC_012563.1 GNAT family acetyltransferase 2859327 7764593 CLM_2852 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002804994.1 2859127 R 536232 CDS YP_002804995.1 226949904 7766908 complement(2860055..2860339) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2860339 7766908 CLM_2855 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804995.1 2860055 R 536232 CDS YP_002804996.1 226949905 7765896 complement(2860350..2861180) 1 NC_012563.1 hypothetical protein 2861180 7765896 CLM_2856 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804996.1 2860350 R 536232 CDS YP_002804997.1 226949906 7764825 complement(2861134..2861937) 1 NC_012563.1 identified by match to protein family HMM PF03837; match to protein family HMM TIGR00616; recombinase, phage RecT family 2861937 7764825 CLM_2857 Clostridium botulinum A2 str. Kyoto recombinase, phage RecT family YP_002804997.1 2861134 R 536232 CDS YP_002804998.1 226949907 7765167 2862584..2862736 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2862736 7765167 CLM_2859 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002804998.1 2862584 D 536232 CDS YP_002804999.1 226949908 7766556 complement(2862954..2864624) 1 NC_012563.1 identified by match to protein family HMM PF00905; penicillin-binding protein 2864624 7766556 CLM_2860 Clostridium botulinum A2 str. Kyoto penicillin-binding protein YP_002804999.1 2862954 R 536232 CDS YP_002805000.1 226949909 7767411 complement(2864710..2865330) 1 NC_012563.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2865330 udk 7767411 udk Clostridium botulinum A2 str. Kyoto uridine kinase YP_002805000.1 2864710 R 536232 CDS YP_002805001.1 226949910 7767830 complement(2865478..2866704) 1 NC_012563.1 identified by match to protein family HMM PF01136; peptidase, U32 family 2866704 7767830 CLM_2862 Clostridium botulinum A2 str. Kyoto peptidase, U32 family YP_002805001.1 2865478 R 536232 CDS YP_002805002.1 226949911 7764691 complement(2866697..2867353) 1 NC_012563.1 identified by match to protein family HMM PF01596; O-methyltransferase family protein 2867353 7764691 CLM_2863 Clostridium botulinum A2 str. Kyoto O-methyltransferase family protein YP_002805002.1 2866697 R 536232 CDS YP_002805003.1 226949912 7766077 complement(2867436..2868467) 1 NC_012563.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247; hypothetical protein 2868467 7766077 CLM_2864 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805003.1 2867436 R 536232 CDS YP_002805004.1 226949913 7766979 complement(2868545..2870371) 1 NC_012563.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein TypA 2870371 typA 7766979 typA Clostridium botulinum A2 str. Kyoto GTP-binding protein TypA YP_002805004.1 2868545 R 536232 CDS YP_002805005.1 226949914 7767214 complement(2871015..2872724) 1 NC_012563.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649; RNA-metabolizing metallo-beta-lactamase family protein 2872724 7767214 CLM_2866 Clostridium botulinum A2 str. Kyoto RNA-metabolizing metallo-beta-lactamase family protein YP_002805005.1 2871015 R 536232 CDS YP_002805006.1 226949915 7764505 complement(2872772..2873224) 1 NC_012563.1 identified by match to protein family HMM PF01475; Fur family transcriptional regulator 2873224 7764505 CLM_2867 Clostridium botulinum A2 str. Kyoto Fur family transcriptional regulator YP_002805006.1 2872772 R 536232 CDS YP_002805007.1 226949916 7765583 complement(2873346..2873600) 1 NC_012563.1 identified by match to protein family HMM PF06949; hypothetical protein 2873600 7765583 CLM_2868 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805007.1 2873346 R 536232 CDS YP_002805008.1 226949917 7765712 complement(2873614..2874027) 1 NC_012563.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 2874027 7765712 CLM_2869 Clostridium botulinum A2 str. Kyoto Holliday junction resolvase-like protein YP_002805008.1 2873614 R 536232 CDS YP_002805009.1 226949918 7764823 complement(2874234..2874485) 1 NC_012563.1 identified by match to protein family HMM PF06135; hypothetical protein 2874485 7764823 CLM_2870 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805009.1 2874234 R 536232 CDS YP_002805010.1 226949919 7767519 complement(2874600..2877239) 1 NC_012563.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 2877239 alaS 7767519 alaS Clostridium botulinum A2 str. Kyoto alanyl-tRNA synthetase YP_002805010.1 2874600 R 536232 CDS YP_002805011.1 226949920 7766563 complement(2877685..2878713) 1 NC_012563.1 identified by match to protein family HMM PF01594; hypothetical protein 2878713 7766563 CLM_2872 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805011.1 2877685 R 536232 CDS YP_002805012.1 226949921 7765184 complement(2878726..2879214) 1 NC_012563.1 PRC-barrel domain-containing protein 2879214 7765184 CLM_2873 Clostridium botulinum A2 str. Kyoto PRC-barrel domain-containing protein YP_002805012.1 2878726 R 536232 CDS YP_002805013.1 226949922 7764333 complement(2879396..2879824) 1 NC_012563.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR03419; FeS cluster assembly scaffold protein NifU 2879824 nifU 7764333 nifU Clostridium botulinum A2 str. Kyoto FeS cluster assembly scaffold protein NifU YP_002805013.1 2879396 R 536232 CDS YP_002805014.1 226949923 7767643 complement(2879826..2881019) 1 NC_012563.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR03402; cysteine desulfurase 2881019 iscS 7767643 iscS Clostridium botulinum A2 str. Kyoto cysteine desulfurase YP_002805014.1 2879826 R 536232 CDS YP_002805015.1 226949924 7766587 complement(2881012..2881458) 1 NC_012563.1 identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738; rrF2 family protein 2881458 7766587 CLM_2876 Clostridium botulinum A2 str. Kyoto rrF2 family protein YP_002805015.1 2881012 R 536232 CDS YP_002805016.1 226949925 7765238 complement(2881678..2882928) 1 NC_012563.1 identified by match to protein family HMM PF00004; recombination factor protein RarA 2882928 7765238 CLM_2877 Clostridium botulinum A2 str. Kyoto recombination factor protein RarA YP_002805016.1 2881678 R 536232 CDS YP_002805017.1 226949926 7764395 complement(2883265..2884032) 1 NC_012563.1 identified by match to protein family HMM PF02811; match to protein family HMM TIGR01856; histidinol-phosphatase 2884032 hisJ 7764395 hisJ Clostridium botulinum A2 str. Kyoto histidinol-phosphatase YP_002805017.1 2883265 R 536232 CDS YP_002805018.1 226949927 7765399 complement(2884296..2885204) 1 NC_012563.1 identified by match to protein family HMM PF03547; auxin efflux carrier family protein 2885204 7765399 CLM_2879 Clostridium botulinum A2 str. Kyoto auxin efflux carrier family protein YP_002805018.1 2884296 R 536232 CDS YP_002805019.1 226949928 7764318 complement(2885312..2886178) 1 NC_012563.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; DegV family protein 2886178 7764318 CLM_2880 Clostridium botulinum A2 str. Kyoto DegV family protein YP_002805019.1 2885312 R 536232 CDS YP_002805020.1 226949929 7768030 2886506..2887090 1 NC_012563.1 identified by match to protein family HMM PF01206; match to protein family HMM TIGR03527; selenium metabolism protein YedF 2887090 7768030 CLM_2881 Clostridium botulinum A2 str. Kyoto selenium metabolism protein YedF YP_002805020.1 2886506 D 536232 CDS YP_002805021.1 226949930 7767025 complement(2887342..2888331) 1 NC_012563.1 catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase 2888331 7767025 CLM_2882 Clostridium botulinum A2 str. Kyoto ornithine cyclodeaminase YP_002805021.1 2887342 R 536232 CDS YP_002805022.1 226949931 7764430 complement(2888453..2889820) 1 NC_012563.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 2889820 7764430 CLM_2883 Clostridium botulinum A2 str. Kyoto sodium:alanine symporter family protein YP_002805022.1 2888453 R 536232 CDS YP_002805023.1 226949932 7765582 complement(2890564..2891898) 1 NC_012563.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 2891898 7765582 CLM_2884 Clostridium botulinum A2 str. Kyoto sodium:alanine symporter family protein YP_002805023.1 2890564 R 536232 CDS YP_002805024.1 226949933 7766199 2892274..2892927 1 NC_012563.1 hypothetical protein 2892927 7766199 CLM_2885 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805024.1 2892274 D 536232 CDS YP_002805025.1 226949934 7767335 complement(2893065..2893541) 1 NC_012563.1 identified by match to protein family HMM PF07833; copper amine oxidase domain-containing protein 2893541 7767335 CLM_2886 Clostridium botulinum A2 str. Kyoto copper amine oxidase domain-containing protein YP_002805025.1 2893065 R 536232 CDS YP_002805026.1 226949935 7767542 complement(2893906..2897667) 1 NC_012563.1 identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857; phosphoribosylformylglycinamidine synthase 2897667 7767542 CLM_2887 Clostridium botulinum A2 str. Kyoto phosphoribosylformylglycinamidine synthase YP_002805026.1 2893906 R 536232 CDS YP_002805027.1 226949936 7764232 complement(2897865..2899214) 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; MATE efflux family protein 2899214 7764232 CLM_2888 Clostridium botulinum A2 str. Kyoto MATE efflux family protein YP_002805027.1 2897865 R 536232 CDS YP_002805028.1 226949937 7766601 complement(2899211..2901688) 1 NC_012563.1 identified by match to protein family HMM PF00391; match to protein family HMM PF01326; putative phosphoenolpyruvate synthase 2901688 7766601 CLM_2889 Clostridium botulinum A2 str. Kyoto putative phosphoenolpyruvate synthase YP_002805028.1 2899211 R 536232 CDS YP_002805029.1 226949938 7767634 complement(2901693..2901968) 1 NC_012563.1 acyl carrier protein 2901968 7767634 CLM_2890 Clostridium botulinum A2 str. Kyoto acyl carrier protein YP_002805029.1 2901693 R 536232 CDS YP_002805030.1 226949939 7764352 complement(2901974..2903512) 1 NC_012563.1 identified by match to protein family HMM PF00501; putative acyl-CoA synthetase 2903512 7764352 CLM_2891 Clostridium botulinum A2 str. Kyoto putative acyl-CoA synthetase YP_002805030.1 2901974 R 536232 CDS YP_002805031.1 226949940 7766109 complement(2903529..2904539) 1 NC_012563.1 identified by match to protein family HMM PF08541; match to protein family HMM PF08545; 3-oxoacyl-ACP synthase III 2904539 7766109 CLM_2892 Clostridium botulinum A2 str. Kyoto 3-oxoacyl-ACP synthase III YP_002805031.1 2903529 R 536232 CDS YP_002805032.1 226949941 7766592 complement(2904548..2905405) 1 NC_012563.1 putative bacT protein 2905405 7766592 CLM_2893 Clostridium botulinum A2 str. Kyoto putative bacT protein YP_002805032.1 2904548 R 536232 CDS YP_002805033.1 226949942 7767646 complement(2905446..2907275) 1 NC_012563.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; putative nonribosomal peptide synthetase 2907275 7767646 CLM_2894 Clostridium botulinum A2 str. Kyoto putative nonribosomal peptide synthetase YP_002805033.1 2905446 R 536232 CDS YP_002805034.1 226949943 7767663 complement(2907315..2907827) 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 2907827 7767663 CLM_2895 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002805034.1 2907315 R 536232 CDS YP_002805035.1 226949944 7765729 complement(2907831..2908079) 1 NC_012563.1 D-alanyl carrier protein 2908079 7765729 CLM_2896 Clostridium botulinum A2 str. Kyoto D-alanyl carrier protein YP_002805035.1 2907831 R 536232 CDS YP_002805036.1 226949945 7766896 complement(2908088..2909104) 1 NC_012563.1 hypothetical protein 2909104 7766896 CLM_2897 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805036.1 2908088 R 536232 CDS YP_002805037.1 226949946 7768057 complement(2909101..2910294) 1 NC_012563.1 putative seryl-tRNA synthetase 2910294 7768057 CLM_2898 Clostridium botulinum A2 str. Kyoto putative seryl-tRNA synthetase YP_002805037.1 2909101 R 536232 CDS YP_002805038.1 226949947 7767352 complement(2910313..2911053) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2911053 7767352 CLM_2899 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805038.1 2910313 R 536232 CDS YP_002805039.1 226949948 7765968 complement(2911518..2912519) 1 NC_012563.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 2912519 argF 7765968 argF Clostridium botulinum A2 str. Kyoto ornithine carbamoyltransferase YP_002805039.1 2911518 R 536232 CDS YP_002805040.1 226949949 7765075 complement(2912614..2913558) 1 NC_012563.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2913558 arcC 7765075 arcC Clostridium botulinum A2 str. Kyoto carbamate kinase YP_002805040.1 2912614 R 536232 CDS YP_002805041.1 226949950 7767754 complement(2914122..2915363) 1 NC_012563.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2915363 glyA 7767754 glyA Clostridium botulinum A2 str. Kyoto serine hydroxymethyltransferase YP_002805041.1 2914122 R 536232 CDS YP_002805042.1 226949951 7766759 2915537..2916307 1 NC_012563.1 identified by match to protein family HMM PF06738; hypothetical protein 2916307 7766759 CLM_2903 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805042.1 2915537 D 536232 CDS YP_002805043.1 226949952 7766141 2916304..2916792 1 NC_012563.1 hypothetical protein 2916792 7766141 CLM_2904 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805043.1 2916304 D 536232 CDS YP_002805044.1 226949953 7764930 complement(2916859..2917128) 1 NC_012563.1 identified by match to protein family HMM PF02583; hypothetical protein 2917128 7764930 CLM_2905 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805044.1 2916859 R 536232 CDS YP_002805045.1 226949954 7764356 complement(2917329..2918153) 1 NC_012563.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD superfamily hydrolase 2918153 7764356 CLM_2906 Clostridium botulinum A2 str. Kyoto HAD superfamily hydrolase YP_002805045.1 2917329 R 536232 CDS YP_002805046.1 226949955 7764916 2918266..2918742 1 NC_012563.1 putative lipoprotein 2918742 7764916 CLM_2908 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002805046.1 2918266 D 536232 CDS YP_002805047.1 226949956 7765756 2919153..2924018 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2924018 7765756 CLM_2909 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805047.1 2919153 D 536232 CDS YP_002805048.1 226949957 7766916 2924095..2925318 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2925318 7766916 CLM_2910 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805048.1 2924095 D 536232 CDS YP_002805049.1 226949958 7767674 2925472..2926527 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2926527 7767674 CLM_2911 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805049.1 2925472 D 536232 CDS YP_002805050.1 226949959 7767717 2926866..2927558 1 NC_012563.1 identified by similarity to GB:ABS33456.1; hypothetical protein 2927558 7767717 CLM_2912 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805050.1 2926866 D 536232 CDS YP_002805051.1 226949960 7764767 complement(2928193..2928426) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2928426 7764767 CLM_2913 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805051.1 2928193 R 536232 CDS YP_002805052.1 226949961 7765338 complement(2928614..2929201) 1 NC_012563.1 hypothetical protein 2929201 7765338 CLM_2914 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805052.1 2928614 R 536232 CDS YP_002805053.1 226949962 7766466 complement(2929330..2930091) 1 NC_012563.1 identified by match to protein family HMM PF01520; match to protein family HMM PF08239; bacteriophage endolysin 2930091 7766466 CLM_2915 Clostridium botulinum A2 str. Kyoto bacteriophage endolysin YP_002805053.1 2929330 R 536232 CDS YP_002805054.1 226949963 7765967 complement(2930133..2930306) 1 NC_012563.1 hypothetical protein 2930306 7765967 CLM_2916 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805054.1 2930133 R 536232 CDS YP_002805055.1 226949964 7764687 complement(2930308..2930511) 1 NC_012563.1 identified by similarity to SP:P15936; bacteriocin UviB 2930511 7764687 CLM_2917 Clostridium botulinum A2 str. Kyoto bacteriocin UviB YP_002805055.1 2930308 R 536232 CDS YP_002805056.1 226949965 7768096 complement(2930609..2930770) 1 NC_012563.1 hypothetical protein 2930770 7768096 CLM_2918 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805056.1 2930609 R 536232 CDS YP_002805057.1 226949966 7766982 complement(2930770..2931066) 1 NC_012563.1 hypothetical protein 2931066 7766982 CLM_2919 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805057.1 2930770 R 536232 CDS YP_002805058.1 226949967 7764348 complement(2931078..2932346) 1 NC_012563.1 hypothetical protein 2932346 7764348 CLM_2920 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805058.1 2931078 R 536232 CDS YP_002805059.1 226949968 7767442 complement(2932346..2933503) 1 NC_012563.1 hypothetical protein 2933503 7767442 CLM_2921 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805059.1 2932346 R 536232 CDS YP_002805060.1 226949969 7766487 complement(2933507..2934376) 1 NC_012563.1 hypothetical protein 2934376 7766487 CLM_2922 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805060.1 2933507 R 536232 CDS YP_002805061.1 226949970 7765367 complement(2934392..2938318) 1 NC_012563.1 identified by match to protein family HMM TIGR01760; phage tail tape measure protein, family 2938318 7765367 CLM_2923 Clostridium botulinum A2 str. Kyoto phage tail tape measure protein, family YP_002805061.1 2934392 R 536232 CDS YP_002805062.1 226949971 7766963 complement(2938375..2938494) 1 NC_012563.1 hypothetical protein 2938494 7766963 CLM_2924 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805062.1 2938375 R 536232 CDS YP_002805063.1 226949972 7765799 complement(2938608..2939000) 1 NC_012563.1 hypothetical protein 2939000 7765799 CLM_2925 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805063.1 2938608 R 536232 CDS YP_002805064.1 226949973 7764423 complement(2939058..2939639) 1 NC_012563.1 identified by match to protein family HMM TIGR01603; phage major tail protein, Phi13 family 2939639 7764423 CLM_2926 Clostridium botulinum A2 str. Kyoto phage major tail protein, Phi13 family YP_002805064.1 2939058 R 536232 CDS YP_002805065.1 226949974 7767262 complement(2939703..2940059) 1 NC_012563.1 hypothetical protein 2940059 7767262 CLM_2927 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805065.1 2939703 R 536232 CDS YP_002805066.1 226949975 7766647 complement(2940075..2940434) 1 NC_012563.1 identified by match to protein family HMM TIGR01725; phage protein, HK97 gp10 family 2940434 7766647 CLM_2928 Clostridium botulinum A2 str. Kyoto phage protein, HK97 gp10 family YP_002805066.1 2940075 R 536232 CDS YP_002805067.1 226949976 7765420 complement(2940435..2940803) 1 NC_012563.1 identified by match to protein family HMM TIGR01563; phage head-tail adaptor protein 2940803 7765420 CLM_2929 Clostridium botulinum A2 str. Kyoto phage head-tail adaptor protein YP_002805067.1 2940435 R 536232 CDS YP_002805068.1 226949977 7765858 complement(2940793..2941086) 1 NC_012563.1 identified by match to protein family HMM PF05135; match to protein family HMM TIGR01560; hypothetical protein 2941086 7765858 CLM_2930 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805068.1 2940793 R 536232 CDS YP_002805069.1 226949978 7766830 complement(2941171..2942403) 1 NC_012563.1 identified by match to protein family HMM PF05065; match to protein family HMM TIGR01554; phage major capsid protein, HK97 family 2942403 7766830 CLM_2931 Clostridium botulinum A2 str. Kyoto phage major capsid protein, HK97 family YP_002805069.1 2941171 R 536232 CDS YP_002805070.1 226949979 7766019 complement(2942477..2943202) 1 NC_012563.1 identified by match to protein family HMM PF00574; Clp protease 2943202 clpP 7766019 clpP Clostridium botulinum A2 str. Kyoto Clp protease YP_002805070.1 2942477 R 536232 CDS YP_002805071.1 226949980 7766390 complement(2943195..2944445) 1 NC_012563.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; phage portal protein, HK97 family 2944445 7766390 CLM_2933 Clostridium botulinum A2 str. Kyoto phage portal protein, HK97 family YP_002805071.1 2943195 R 536232 CDS YP_002805072.1 226949981 7767254 complement(2944489..2944671) 1 NC_012563.1 hypothetical protein 2944671 7767254 CLM_2934 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805072.1 2944489 R 536232 CDS YP_002805073.1 226949982 7764482 complement(2944695..2946452) 1 NC_012563.1 identified by match to protein family HMM PF03354; putative phage terminase large subunit 2946452 7764482 CLM_2935 Clostridium botulinum A2 str. Kyoto putative phage terminase large subunit YP_002805073.1 2944695 R 536232 CDS YP_002805074.1 226949983 7764863 complement(2946453..2946938) 1 NC_012563.1 identified by match to protein family HMM PF05119; match to protein family HMM TIGR01558; phage terminase small subunit, P27 family 2946938 7764863 CLM_2936 Clostridium botulinum A2 str. Kyoto phage terminase small subunit, P27 family YP_002805074.1 2946453 R 536232 CDS YP_002805075.1 226949984 7765727 complement(2947085..2947552) 1 NC_012563.1 identified by match to protein family HMM PF01844; HNH endonuclease domain-containing protein 2947552 7765727 CLM_2937 Clostridium botulinum A2 str. Kyoto HNH endonuclease domain-containing protein YP_002805075.1 2947085 R 536232 CDS YP_002805076.1 226949985 7767106 complement(2947653..2949446) 1 NC_012563.1 hypothetical protein 2949446 7767106 CLM_2938 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805076.1 2947653 R 536232 CDS YP_002805077.1 226949986 7767908 complement(2949665..2950258) 1 NC_012563.1 hypothetical protein 2950258 7767908 CLM_2939 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805077.1 2949665 R 536232 CDS YP_002805078.1 226949987 7764422 complement(2950280..2950477) 1 NC_012563.1 hypothetical protein 2950477 7764422 CLM_2940 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805078.1 2950280 R 536232 CDS YP_002805079.1 226949988 7767549 complement(2950507..2950752) 1 NC_012563.1 hypothetical protein 2950752 7767549 CLM_2941 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805079.1 2950507 R 536232 CDS YP_002805080.1 226949989 7765667 complement(2950877..2951059) 1 NC_012563.1 hypothetical protein 2951059 7765667 CLM_2942 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805080.1 2950877 R 536232 CDS YP_002805081.1 226949990 7764808 complement(2951128..2951340) 1 NC_012563.1 hypothetical protein 2951340 7764808 CLM_2943 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805081.1 2951128 R 536232 CDS YP_002805082.1 226949991 7767989 complement(2951417..2951737) 1 NC_012563.1 hypothetical protein 2951737 7767989 CLM_2944 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805082.1 2951417 R 536232 CDS YP_002805083.1 226949992 7767154 complement(2951768..2951962) 1 NC_012563.1 hypothetical protein 2951962 7767154 CLM_2945 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805083.1 2951768 R 536232 CDS YP_002805084.1 226949993 7765544 complement(2951963..2952211) 1 NC_012563.1 hypothetical protein 2952211 7765544 CLM_2946 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805084.1 2951963 R 536232 CDS YP_002805085.1 226949994 7764229 complement(2952259..2952846) 1 NC_012563.1 GIY-YIG domain-containing protein 2952846 7764229 CLM_2947 Clostridium botulinum A2 str. Kyoto GIY-YIG domain-containing protein YP_002805085.1 2952259 R 536232 CDS YP_002805086.1 226949995 7767492 complement(2953142..2953597) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2953597 7767492 CLM_2948 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805086.1 2953142 R 536232 CDS YP_002805087.1 226949996 7766323 complement(2953625..2953921) 1 NC_012563.1 hypothetical protein 2953921 7766323 CLM_2949 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805087.1 2953625 R 536232 CDS YP_002805088.1 226949997 7765693 complement(2954221..2957115) 1 NC_012563.1 hypothetical protein 2957115 7765693 CLM_2950 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805088.1 2954221 R 536232 CDS YP_002805089.1 226949998 7766998 complement(2957272..2957436) 1 NC_012563.1 hypothetical protein 2957436 7766998 CLM_2951 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805089.1 2957272 R 536232 CDS YP_002805090.1 226949999 7764402 complement(2957795..2958931) 1 NC_012563.1 hypothetical protein 2958931 7764402 CLM_2952 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805090.1 2957795 R 536232 CDS YP_002805091.1 226950000 7765228 complement(2958977..2959930) 1 NC_012563.1 hypothetical protein 2959930 7765228 CLM_2953 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805091.1 2958977 R 536232 CDS YP_002805092.1 226950001 7766589 complement(2960007..2960804) 1 NC_012563.1 hypothetical protein 2960804 7766589 CLM_2954 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805092.1 2960007 R 536232 CDS YP_002805093.1 226950002 7767431 complement(2960854..2961012) 1 NC_012563.1 hypothetical protein 2961012 7767431 CLM_2955 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805093.1 2960854 R 536232 CDS YP_002805094.1 226950003 7764834 complement(2961076..2961495) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2961495 7764834 CLM_2956 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805094.1 2961076 R 536232 CDS YP_002805095.1 226950004 7765943 complement(2961931..2962587) 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 2962587 7765943 CLM_2957 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002805095.1 2961931 R 536232 CDS YP_002805096.1 226950005 7767263 complement(2962719..2962859) 1 NC_012563.1 hypothetical protein 2962859 7767263 CLM_2958 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805096.1 2962719 R 536232 CDS YP_002805097.1 226950006 7768119 complement(2962870..2963199) 1 NC_012563.1 hypothetical protein 2963199 7768119 CLM_2959 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805097.1 2962870 R 536232 CDS YP_002805098.1 226950007 7766145 2963386..2963628 1 NC_012563.1 Cro/CI family transcriptional regulator -like protein 2963628 7766145 CLM_2960 Clostridium botulinum A2 str. Kyoto Cro/CI family transcriptional regulator -like protein YP_002805098.1 2963386 D 536232 CDS YP_002805099.1 226950008 7764989 complement(2963839..2964048) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2964048 7764989 CLM_2961 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805099.1 2963839 R 536232 CDS YP_002805100.1 226950009 7766108 2964290..2964736 1 NC_012563.1 identified by match to protein family HMM PF04471; putative restriction endonuclase 2964736 7766108 CLM_2962 Clostridium botulinum A2 str. Kyoto putative restriction endonuclase YP_002805100.1 2964290 D 536232 CDS YP_002805101.1 226950010 7764944 complement(2964855..2965538) 1 NC_012563.1 hypothetical protein 2965538 7764944 CLM_2963 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805101.1 2964855 R 536232 CDS YP_002805102.1 226950011 7766378 complement(2965604..2965834) 1 NC_012563.1 putative ParB protein 2965834 7766378 CLM_2964 Clostridium botulinum A2 str. Kyoto putative ParB protein YP_002805102.1 2965604 R 536232 CDS YP_002805103.1 226950012 7765216 complement(2965848..2966096) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 2966096 7765216 CLM_2965 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805103.1 2965848 R 536232 CDS YP_002805104.1 226950013 7764672 complement(2966886..2967818) 1 NC_012563.1 identified by match to protein family HMM PF00589; phage integrase family site-specific recombinase 2967818 7764672 CLM_2966 Clostridium botulinum A2 str. Kyoto phage integrase family site-specific recombinase YP_002805104.1 2966886 R 536232 CDS YP_002805105.1 226950014 7767740 complement(2967953..2969488) 1 NC_012563.1 catalyzes the removal of amino acids from the N termini of peptides; putative aminopeptidase 1 2969488 7767740 CLM_2967 Clostridium botulinum A2 str. Kyoto putative aminopeptidase 1 YP_002805105.1 2967953 R 536232 CDS YP_002805106.1 226950015 7766907 complement(2969479..2970414) 1 NC_012563.1 identified by match to protein family HMM PF01544; putative magnesium and cobalt transport protein CorA 2970414 7766907 CLM_2968 Clostridium botulinum A2 str. Kyoto putative magnesium and cobalt transport protein CorA YP_002805106.1 2969479 R 536232 CDS YP_002805107.1 226950016 7765971 complement(2970872..2971426) 1 NC_012563.1 identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727; 5-formyltetrahydrofolate cyclo-ligase 2971426 7765971 CLM_2969 Clostridium botulinum A2 str. Kyoto 5-formyltetrahydrofolate cyclo-ligase YP_002805107.1 2970872 R 536232 CDS YP_002805108.1 226950017 7767427 complement(2971419..2972342) 1 NC_012563.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 2972342 hprK 7767427 hprK Clostridium botulinum A2 str. Kyoto HPr kinase/phosphorylase YP_002805108.1 2971419 R 536232 CDS YP_002805109.1 226950018 7764297 complement(2972374..2972562) 1 NC_012563.1 identified by match to protein family HMM PF05979; hypothetical protein 2972562 7764297 CLM_2971 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805109.1 2972374 R 536232 CDS YP_002805110.1 226950019 7766800 complement(2972733..2973470) 1 NC_012563.1 identified by match to protein family HMM PF09335; hypothetical protein 2973470 7766800 CLM_2972 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805110.1 2972733 R 536232 CDS YP_002805111.1 226950020 7767768 complement(2973436..2974155) 1 NC_012563.1 identified by match to protein family HMM PF09335; hypothetical protein 2974155 7767768 CLM_2973 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805111.1 2973436 R 536232 CDS YP_002805112.1 226950021 7765085 complement(2974264..2975409) 1 NC_012563.1 identified by match to protein family HMM PF02754; cysteine-rich domain-containing protein 2975409 7765085 CLM_2974 Clostridium botulinum A2 str. Kyoto cysteine-rich domain-containing protein YP_002805112.1 2974264 R 536232 CDS YP_002805113.1 226950022 7765922 complement(2975409..2976395) 1 NC_012563.1 hypothetical protein 2976395 7765922 CLM_2975 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805113.1 2975409 R 536232 CDS YP_002805114.1 226950023 7766300 complement(2976385..2977086) 1 NC_012563.1 hypothetical protein 2977086 7766300 CLM_2976 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805114.1 2976385 R 536232 CDS YP_002805115.1 226950024 7767412 complement(2977086..2977760) 1 NC_012563.1 identified by match to protein family HMM PF00535; group 2 family glycosyl transferase 2977760 7767412 CLM_2977 Clostridium botulinum A2 str. Kyoto group 2 family glycosyl transferase YP_002805115.1 2977086 R 536232 CDS YP_002805116.1 226950025 7768069 2977947..2978921 1 NC_012563.1 identified by match to protein family HMM PF00581; putative thiosulfate sulfurtransferase 2978921 7768069 CLM_2978 Clostridium botulinum A2 str. Kyoto putative thiosulfate sulfurtransferase YP_002805116.1 2977947 D 536232 CDS YP_002805117.1 226950026 7765193 complement(2979147..2980121) 1 NC_012563.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 2980121 glpX 7765193 glpX Clostridium botulinum A2 str. Kyoto fructose 1,6-bisphosphatase II YP_002805117.1 2979147 R 536232 CDS YP_002805118.1 226950027 7765622 2980605..2980781 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 2980781 7765622 CLM_2980 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805118.1 2980605 D 536232 CDS YP_002805119.1 226950028 7764465 complement(2980813..2981211) 1 NC_012563.1 hypothetical protein 2981211 7764465 CLM_2981 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805119.1 2980813 R 536232 CDS YP_002805120.1 226950029 7764461 complement(2981666..2982835) 1 NC_012563.1 identified by match to protein family HMM PF00258; match to protein family HMM PF00753; metallo-beta-lactamase family protein/flavodoxin 2982835 7764461 CLM_2982 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein/flavodoxin YP_002805120.1 2981666 R 536232 CDS YP_002805121.1 226950030 7767291 complement(2983383..2983889) 1 NC_012563.1 hypothetical protein 2983889 7767291 CLM_2983 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805121.1 2983383 R 536232 CDS YP_002805122.1 226950031 7766100 complement(2984941..2985804) 1 NC_012563.1 identified by match to protein family HMM PF01156; nucleoside hydrolase, IUNH family 2985804 7766100 CLM_2984 Clostridium botulinum A2 str. Kyoto nucleoside hydrolase, IUNH family YP_002805122.1 2984941 R 536232 CDS YP_002805123.1 226950032 7765237 complement(2985821..2986357) 1 NC_012563.1 identified by match to protein family HMM PF01327; match to protein family HMM TIGR00079; peptide deformylase 2986357 def 7765237 def Clostridium botulinum A2 str. Kyoto peptide deformylase YP_002805123.1 2985821 R 536232 CDS YP_002805124.1 226950033 7766753 2986459..2986575 1 NC_012563.1 hypothetical protein 2986575 7766753 CLM_2986 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805124.1 2986459 D 536232 CDS YP_002805125.1 226950034 7765840 complement(2986667..2987317) 1 NC_012563.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the D subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit D 2987317 7765840 CLM_2987 Clostridium botulinum A2 str. Kyoto V-type ATP synthase subunit D YP_002805125.1 2986667 R 536232 CDS YP_002805126.1 226950035 7764331 complement(2987346..2988731) 1 NC_012563.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the B subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit B 2988731 7764331 CLM_2988 Clostridium botulinum A2 str. Kyoto V-type ATP synthase subunit B YP_002805126.1 2987346 R 536232 CDS YP_002805127.1 226950036 7767407 complement(2988724..2990502) 1 NC_012563.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit A 2990502 7767407 CLM_2989 Clostridium botulinum A2 str. Kyoto V-type ATP synthase subunit A YP_002805127.1 2988724 R 536232 CDS YP_002805128.1 226950037 7764948 complement(2990516..2990833) 1 NC_012563.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the F subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit F 2990833 7764948 CLM_2990 Clostridium botulinum A2 str. Kyoto V-type ATP synthase subunit F YP_002805128.1 2990516 R 536232 CDS YP_002805129.1 226950038 7767307 complement(2990817..2991818) 1 NC_012563.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the C subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit C 2991818 7767307 CLM_2991 Clostridium botulinum A2 str. Kyoto V-type ATP synthase subunit C YP_002805129.1 2990817 R 536232 CDS YP_002805130.1 226950039 7765343 complement(2991833..2992432) 1 NC_012563.1 identified by match to protein family HMM PF01991; V-type ATPase subunit E 2992432 7765343 CLM_2992 Clostridium botulinum A2 str. Kyoto V-type ATPase subunit E YP_002805130.1 2991833 R 536232 CDS YP_002805131.1 226950040 7764259 complement(2992471..2992947) 1 NC_012563.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; V-type ATP synthase subunit K 2992947 7764259 CLM_2993 Clostridium botulinum A2 str. Kyoto V-type ATP synthase subunit K YP_002805131.1 2992471 R 536232 CDS YP_002805132.1 226950041 7765140 complement(2992960..2994921) 1 NC_012563.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel.; V-type ATP synthase subunit I 2994921 7765140 CLM_2994 Clostridium botulinum A2 str. Kyoto V-type ATP synthase subunit I YP_002805132.1 2992960 R 536232 CDS YP_002805133.1 226950042 7767767 complement(2994908..2995234) 1 NC_012563.1 putative V-type ATPase subunit G 2995234 7767767 CLM_2995 Clostridium botulinum A2 str. Kyoto putative V-type ATPase subunit G YP_002805133.1 2994908 R 536232 CDS YP_002805134.1 226950043 7764644 complement(2995558..2997243) 1 NC_012563.1 identified by match to protein family HMM PF02310; match to protein family HMM PF04055; putative B12-binding Fe-S oxidoreductase 2997243 7764644 CLM_2996 Clostridium botulinum A2 str. Kyoto putative B12-binding Fe-S oxidoreductase YP_002805134.1 2995558 R 536232 CDS YP_002805135.1 226950044 7767518 complement(2997218..2997793) 1 NC_012563.1 hypothetical protein 2997793 7767518 CLM_2997 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805135.1 2997218 R 536232 CDS YP_002805136.1 226950045 7766160 complement(2997965..2998684) 1 NC_012563.1 identified by match to protein family HMM PF00882; putative phospholipase C 2998684 7766160 CLM_2998 Clostridium botulinum A2 str. Kyoto putative phospholipase C YP_002805136.1 2997965 R 536232 CDS YP_002805137.1 226950046 7766064 complement(2998706..2999905) 1 NC_012563.1 hypothetical protein 2999905 7766064 CLM_2999 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805137.1 2998706 R 536232 CDS YP_002805138.1 226950047 7765332 complement(2999944..3002490) 1 NC_012563.1 identified by similarity to SP:P04191; match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; calcium-translocating P-type ATPase 3002490 7765332 CLM_3000 Clostridium botulinum A2 str. Kyoto calcium-translocating P-type ATPase YP_002805138.1 2999944 R 536232 CDS YP_002805139.1 226950048 7766213 3002809..3004452 1 NC_012563.1 catalyzes the hydrolysis of pyrophosphate to phosphate; putative manganese-dependent inorganic pyrophosphatase 3004452 7766213 CLM_3001 Clostridium botulinum A2 str. Kyoto putative manganese-dependent inorganic pyrophosphatase YP_002805139.1 3002809 D 536232 CDS YP_002805140.1 226950049 7766711 complement(3004671..3005249) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3005249 7766711 CLM_3002 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805140.1 3004671 R 536232 CDS YP_002805141.1 226950050 7767811 complement(3005541..3006332) 1 NC_012563.1 makes up the distal portion of the flagellar basal body rod; the Clostridia have 2 adjacent copies of the FlgG gene; flagellar basal body rod protein FlgG 3006332 flgG 7767811 flgG Clostridium botulinum A2 str. Kyoto flagellar basal body rod protein FlgG YP_002805141.1 3005541 R 536232 CDS YP_002805142.1 226950051 7765020 complement(3006387..3007154) 1 NC_012563.1 makes up the distal portion of the flagellar basal body rod; the Clostridia have two adjacent copies of the FlgG gene; flagellar basal body rod protein FlgG 3007154 flgG 7765020 flgG Clostridium botulinum A2 str. Kyoto flagellar basal body rod protein FlgG YP_002805142.1 3006387 R 536232 CDS YP_002805143.1 226950052 7766106 complement(3007220..3007336) 1 NC_012563.1 hypothetical protein 3007336 7766106 CLM_3005 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805143.1 3007220 R 536232 CDS YP_002805144.1 226950053 7766202 complement(3007414..3008052) 1 NC_012563.1 hypothetical protein 3008052 7766202 CLM_3006 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805144.1 3007414 R 536232 CDS YP_002805145.1 226950054 7767253 complement(3008081..3008809) 1 NC_012563.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02479; match to protein family HMM TIGR02937; RNA polymerase sigma factor for flagellar operon FliA 3008809 fliA 7767253 fliA Clostridium botulinum A2 str. Kyoto RNA polymerase sigma factor for flagellar operon FliA YP_002805145.1 3008081 R 536232 CDS YP_002805146.1 226950055 7764410 complement(3008823..3009482) 1 NC_012563.1 identified by match to protein family HMM PF07238; hypothetical protein 3009482 7764410 CLM_3008 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805146.1 3008823 R 536232 CDS YP_002805147.1 226950056 7765603 complement(3009497..3010357) 1 NC_012563.1 identified by match to protein family HMM PF01656; flagellar biosynthesis protein FlhG 3010357 flhG 7765603 flhG Clostridium botulinum A2 str. Kyoto flagellar biosynthesis protein FlhG YP_002805147.1 3009497 R 536232 CDS YP_002805148.1 226950057 7768034 complement(3010351..3011577) 1 NC_012563.1 positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 3011577 flhF 7768034 flhF Clostridium botulinum A2 str. Kyoto flagellar biosynthesis regulator FlhF YP_002805148.1 3010351 R 536232 CDS YP_002805149.1 226950058 7766951 complement(3011574..3013640) 1 NC_012563.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 3013640 flhA 7766951 flhA Clostridium botulinum A2 str. Kyoto flagellar biosynthesis protein FlhA YP_002805149.1 3011574 R 536232 CDS YP_002805150.1 226950059 7764384 complement(3013668..3015497) 1 NC_012563.1 FlhB is a membrane protein responsible for substrate specificity in switching from rod/hook-type export to filament-type export; FliR is required for export of flagellar proteins, although a specific role has not yet been determined; bifunctional flagellar biosynthesis protein FliR/FlhB 3015497 7764384 CLM_3012 Clostridium botulinum A2 str. Kyoto bifunctional flagellar biosynthesis protein FliR/FlhB YP_002805150.1 3013668 R 536232 CDS YP_002805151.1 226950060 7767231 complement(3015531..3015800) 1 NC_012563.1 identified by match to protein family HMM PF01313; match to protein family HMM TIGR01402; flagellar biosynthesis protein FliQ 3015800 fliQ 7767231 fliQ Clostridium botulinum A2 str. Kyoto flagellar biosynthesis protein FliQ YP_002805151.1 3015531 R 536232 CDS YP_002805152.1 226950061 7766039 complement(3015812..3016588) 1 NC_012563.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 3016588 fliP 7766039 fliP Clostridium botulinum A2 str. Kyoto flagellar biosynthesis protein FliP YP_002805152.1 3015812 R 536232 CDS YP_002805153.1 226950062 7764937 complement(3016572..3016979) 1 NC_012563.1 identified by match to protein family HMM TIGR03500; flagellar biosynthesis domain-containing protein 3016979 7764937 CLM_3015 Clostridium botulinum A2 str. Kyoto flagellar biosynthesis domain-containing protein YP_002805153.1 3016572 R 536232 CDS YP_002805154.1 226950063 7764895 complement(3017052..3017573) 1 NC_012563.1 identified by match to protein family HMM PF03748; flagellar basal body-associated protein FliL 3017573 fliL 7764895 fliL Clostridium botulinum A2 str. Kyoto flagellar basal body-associated protein FliL YP_002805154.1 3017052 R 536232 CDS YP_002805155.1 226950064 7767978 complement(3017570..3018313) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00691; chemotaxis motB protein 3018313 motB 7767978 motB Clostridium botulinum A2 str. Kyoto chemotaxis motB protein YP_002805155.1 3017570 R 536232 CDS YP_002805156.1 226950065 7766432 complement(3018306..3019118) 1 NC_012563.1 identified by match to protein family HMM PF01618; chemotaxis MotA protein 3019118 motA 7766432 motA Clostridium botulinum A2 str. Kyoto chemotaxis MotA protein YP_002805156.1 3018306 R 536232 CDS YP_002805157.1 226950066 7765566 complement(3019115..3019324) 1 NC_012563.1 identified by match to protein family HMM PF06289; flagellar protein FlbD 3019324 7765566 CLM_3019 Clostridium botulinum A2 str. Kyoto flagellar protein FlbD YP_002805157.1 3019115 R 536232 CDS YP_002805158.1 226950067 7764286 complement(3019560..3020564) 1 NC_012563.1 identified by match to protein family HMM PF00460; match to protein family HMM PF06429; match to protein family HMM TIGR03506; flagellar hook protein FlgE 3020564 7764286 CLM_3020 Clostridium botulinum A2 str. Kyoto flagellar hook protein FlgE YP_002805158.1 3019560 R 536232 CDS YP_002805159.1 226950068 7765352 complement(3020646..3021065) 1 NC_012563.1 identified by match to protein family HMM TIGR02530; flagellar operon protein 3021065 7765352 CLM_3021 Clostridium botulinum A2 str. Kyoto flagellar operon protein YP_002805159.1 3020646 R 536232 CDS YP_002805160.1 226950069 7765906 complement(3021080..3021901) 1 NC_012563.1 identified by match to protein family HMM PF03963; flagellar hook capping protein 3021901 flgD 7765906 flgD Clostridium botulinum A2 str. Kyoto flagellar hook capping protein YP_002805160.1 3021080 R 536232 CDS YP_002805161.1 226950070 7767073 complement(3021931..3023319) 1 NC_012563.1 identified by match to protein family HMM PF02120; flagellar hook-length control protein 3023319 fliK 7767073 fliK Clostridium botulinum A2 str. Kyoto flagellar hook-length control protein YP_002805161.1 3021931 R 536232 CDS YP_002805162.1 226950071 7767693 complement(3023325..3023762) 1 NC_012563.1 identified by match to protein family HMM TIGR02473; flagellar export protein FliJ 3023762 fliJ 7767693 fliJ Clostridium botulinum A2 str. Kyoto flagellar export protein FliJ YP_002805162.1 3023325 R 536232 CDS YP_002805163.1 226950072 7764746 complement(3023866..3025182) 1 NC_012563.1 identified by match to protein family HMM PF00006; match to protein family HMM PF02874; match to protein family HMM TIGR01026; match to protein family HMM TIGR03496; match to protein family HMM TIGR03497; flagellar protein export ATPase FliI 3025182 fliI 7764746 fliI Clostridium botulinum A2 str. Kyoto flagellar protein export ATPase FliI YP_002805163.1 3023866 R 536232 CDS YP_002805164.1 226950073 7767121 complement(3025222..3025998) 1 NC_012563.1 flagellar assembly protein FliH 3025998 fliH 7767121 fliH Clostridium botulinum A2 str. Kyoto flagellar assembly protein FliH YP_002805164.1 3025222 R 536232 CDS YP_002805165.1 226950074 7764239 complement(3025982..3026995) 1 NC_012563.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 3026995 fliG 7764239 fliG Clostridium botulinum A2 str. Kyoto flagellar motor switch protein G YP_002805165.1 3025982 R 536232 CDS YP_002805166.1 226950075 7764876 complement(3027002..3028582) 1 NC_012563.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 3028582 fliF 7764876 fliF Clostridium botulinum A2 str. Kyoto flagellar MS-ring protein YP_002805166.1 3027002 R 536232 CDS YP_002805167.1 226950076 7766033 complement(3028598..3028912) 1 NC_012563.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 3028912 fliE 7766033 fliE Clostridium botulinum A2 str. Kyoto flagellar hook-basal body protein FliE YP_002805167.1 3028598 R 536232 CDS YP_002805168.1 226950077 7767730 complement(3028924..3029358) 1 NC_012563.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 3029358 flgC 7767730 flgC Clostridium botulinum A2 str. Kyoto flagellar basal body rod protein FlgC YP_002805168.1 3028924 R 536232 CDS YP_002805169.1 226950078 7765122 complement(3029456..3029857) 1 NC_012563.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgB 3029857 flgB 7765122 flgB Clostridium botulinum A2 str. Kyoto flagellar basal body rod protein FlgB YP_002805169.1 3029456 R 536232 CDS YP_002805170.1 226950079 7765991 complement(3030430..3031284) 1 NC_012563.1 identified by match to protein family HMM PF00669; match to protein family HMM PF00700; flagellin 3031284 7765991 CLM_3032 Clostridium botulinum A2 str. Kyoto flagellin YP_002805170.1 3030430 R 536232 CDS YP_002805171.1 226950080 7766344 complement(3031428..3031796) 1 NC_012563.1 hypothetical protein 3031796 7766344 CLM_3033 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805171.1 3031428 R 536232 CDS YP_002805172.1 226950081 7767221 complement(3032336..3033658) 1 NC_012563.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 3033658 argH 7767221 argH Clostridium botulinum A2 str. Kyoto argininosuccinate lyase YP_002805172.1 3032336 R 536232 CDS YP_002805173.1 226950082 7764589 complement(3033680..3034873) 1 NC_012563.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 3034873 argG 7764589 argG Clostridium botulinum A2 str. Kyoto argininosuccinate synthase YP_002805173.1 3033680 R 536232 CDS YP_002805174.1 226950083 7767266 complement(3035168..3035506) 1 NC_012563.1 hypothetical protein 3035506 7767266 CLM_3036 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805174.1 3035168 R 536232 CDS YP_002805175.1 226950084 7764640 complement(3035529..3035873) 1 NC_012563.1 hypothetical protein 3035873 7764640 CLM_3037 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805175.1 3035529 R 536232 CDS YP_002805176.1 226950085 7765512 complement(3036053..3037483) 1 NC_012563.1 identified by match to protein family HMM PF00614; cardiolipin synthetase 3037483 cls 7765512 cls Clostridium botulinum A2 str. Kyoto cardiolipin synthetase YP_002805176.1 3036053 R 536232 CDS YP_002805177.1 226950086 7767839 3037810..3038700 1 NC_012563.1 hypothetical protein 3038700 7767839 CLM_3039 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805177.1 3037810 D 536232 CDS YP_002805178.1 226950087 7767765 complement(3038875..3039060) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3039060 7767765 CLM_3040 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805178.1 3038875 R 536232 CDS YP_002805179.1 226950088 7765499 complement(3039343..3039792) 1 NC_012563.1 identified by match to protein family HMM PF04892; VanZ family protein 3039792 7765499 CLM_3041 Clostridium botulinum A2 str. Kyoto VanZ family protein YP_002805179.1 3039343 R 536232 CDS YP_002805180.1 226950089 7766836 complement(3040043..3041473) 1 NC_012563.1 identified by match to protein family HMM PF01943; polysaccharide biosynthesis protein 3041473 7766836 CLM_3042 Clostridium botulinum A2 str. Kyoto polysaccharide biosynthesis protein YP_002805180.1 3040043 R 536232 CDS YP_002805181.1 226950090 7767171 complement(3041513..3042430) 1 NC_012563.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; NAD-dependent epimerase/dehydratase family protein 3042430 7767171 CLM_3043 Clostridium botulinum A2 str. Kyoto NAD-dependent epimerase/dehydratase family protein YP_002805181.1 3041513 R 536232 CDS YP_002805182.1 226950091 7764639 complement(3042459..3043526) 1 NC_012563.1 identified by match to protein family HMM PF03102; match to protein family HMM PF08666; neuB family protein 3043526 7764639 CLM_3044 Clostridium botulinum A2 str. Kyoto neuB family protein YP_002805182.1 3042459 R 536232 CDS YP_002805183.1 226950092 7764490 complement(3043559..3045220) 1 NC_012563.1 identified by match to protein family HMM PF02348; match to protein family HMM PF04101; cytidylyltransferase domain-containing protein 3045220 7764490 CLM_3045 Clostridium botulinum A2 str. Kyoto cytidylyltransferase domain-containing protein YP_002805183.1 3043559 R 536232 CDS YP_002805184.1 226950093 7765551 complement(3045235..3046404) 1 NC_012563.1 hypothetical protein 3046404 7765551 CLM_3046 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805184.1 3045235 R 536232 CDS YP_002805185.1 226950094 7766133 complement(3046438..3047391) 1 NC_012563.1 identified by match to protein family HMM PF05855; lipooligosaccharide sialyltransferase 3047391 7766133 CLM_3047 Clostridium botulinum A2 str. Kyoto lipooligosaccharide sialyltransferase YP_002805185.1 3046438 R 536232 CDS YP_002805186.1 226950095 7767165 complement(3047418..3048188) 1 NC_012563.1 exopolysaccharide biosynthesis protein 3048188 7767165 CLM_3048 Clostridium botulinum A2 str. Kyoto exopolysaccharide biosynthesis protein YP_002805186.1 3047418 R 536232 CDS YP_002805187.1 226950096 7764883 complement(3048188..3049288) 1 NC_012563.1 identified by match to protein family HMM PF03275; match to protein family HMM TIGR00031; UDP-galactopyranose mutase 3049288 glf 7764883 glf Clostridium botulinum A2 str. Kyoto UDP-galactopyranose mutase YP_002805187.1 3048188 R 536232 CDS YP_002805188.1 226950097 7764325 complement(3049393..3050070) 1 NC_012563.1 identified by match to protein family HMM PF02397; UDP-phosphate galactose phosphotransferase 3050070 7764325 CLM_3050 Clostridium botulinum A2 str. Kyoto UDP-phosphate galactose phosphotransferase YP_002805188.1 3049393 R 536232 CDS YP_002805189.1 226950098 7764659 complement(3050281..3050991) 1 NC_012563.1 identified by match to protein family HMM TIGR01007; capsular exopolysaccharide family protein 3050991 7764659 CLM_3051 Clostridium botulinum A2 str. Kyoto capsular exopolysaccharide family protein YP_002805189.1 3050281 R 536232 CDS YP_002805190.1 226950099 7766765 complement(3051010..3051783) 1 NC_012563.1 identified by match to protein family HMM PF02811; exopolysaccharide biosynthesis protein 3051783 7766765 CLM_3052 Clostridium botulinum A2 str. Kyoto exopolysaccharide biosynthesis protein YP_002805190.1 3051010 R 536232 CDS YP_002805191.1 226950100 7766306 complement(3051788..3052471) 1 NC_012563.1 identified by match to protein family HMM PF02706; capsular polysaccharide biosynthsis protein 3052471 7766306 CLM_3053 Clostridium botulinum A2 str. Kyoto capsular polysaccharide biosynthsis protein YP_002805191.1 3051788 R 536232 CDS YP_002805192.1 226950101 7765430 complement(3052506..3053468) 1 NC_012563.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; cell envelope-like transcriptional attenuator domain-containing protein 3053468 7765430 CLM_3054 Clostridium botulinum A2 str. Kyoto cell envelope-like transcriptional attenuator domain-containing protein YP_002805192.1 3052506 R 536232 CDS YP_002805193.1 226950102 7766518 complement(3053933..3054088) 1 NC_012563.1 hypothetical protein 3054088 7766518 CLM_3055 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805193.1 3053933 R 536232 CDS YP_002805194.1 226950103 7765376 complement(3054238..3054411) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3054411 7765376 CLM_3056 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805194.1 3054238 R 536232 CDS YP_002805195.1 226950104 7767762 complement(3054532..3054699) 1 NC_012563.1 hypothetical protein 3054699 7767762 CLM_3057 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805195.1 3054532 R 536232 CDS YP_002805196.1 226950105 7767570 complement(3054839..3054985) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3054985 7767570 CLM_3058 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805196.1 3054839 R 536232 CDS YP_002805197.1 226950106 7766024 complement(3055183..3056031) 1 NC_012563.1 identified by match to protein family HMM PF00015; methyl-accepting chemotaxis protein 3056031 7766024 CLM_3059 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002805197.1 3055183 R 536232 CDS YP_002805198.1 226950107 7766619 complement(3056108..3056926) 1 NC_012563.1 identified by match to protein family HMM PF00669; match to protein family HMM PF00700; flagellin 3056926 fliC 7766619 fliC Clostridium botulinum A2 str. Kyoto flagellin YP_002805198.1 3056108 R 536232 CDS YP_002805199.1 226950108 7766615 complement(3057111..3057608) 1 NC_012563.1 hypothetical protein 3057608 7766615 CLM_3061 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805199.1 3057111 R 536232 CDS YP_002805200.1 226950109 7767227 complement(3057694..3059163) 1 NC_012563.1 hypothetical protein 3059163 7767227 CLM_3062 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805200.1 3057694 R 536232 CDS YP_002805201.1 226950110 7764380 complement(3059382..3060392) 1 NC_012563.1 identified by match to protein family HMM TIGR03590; glycosyl transferase-like protein 3060392 7764380 CLM_3064 Clostridium botulinum A2 str. Kyoto glycosyl transferase-like protein YP_002805201.1 3059382 R 536232 CDS YP_002805202.1 226950111 7766934 complement(3060887..3061891) 1 NC_012563.1 identified by match to protein family HMM PF00657; lipase/acylhydrolase, GDSL family 3061891 7766934 CLM_3065 Clostridium botulinum A2 str. Kyoto lipase/acylhydrolase, GDSL family YP_002805202.1 3060887 R 536232 CDS YP_002805203.1 226950112 7766923 complement(3061981..3063087) 1 NC_012563.1 hypothetical protein 3063087 7766923 CLM_3066 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805203.1 3061981 R 536232 CDS YP_002805204.1 226950113 7768107 complement(3063111..3064226) 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF00535; match to protein family HMM PF07719; family 2 glycosyl transferase 3064226 7768107 CLM_3067 Clostridium botulinum A2 str. Kyoto family 2 glycosyl transferase YP_002805204.1 3063111 R 536232 CDS YP_002805205.1 226950114 7764744 complement(3064244..3065107) 1 NC_012563.1 hypothetical protein 3065107 7764744 CLM_3068 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805205.1 3064244 R 536232 CDS YP_002805206.1 226950115 7765837 complement(3065114..3066442) 1 NC_012563.1 identified by match to protein family HMM PF00534; TPR/glycosyl transferase domain-containing protein 3066442 7765837 CLM_3069 Clostridium botulinum A2 str. Kyoto TPR/glycosyl transferase domain-containing protein YP_002805206.1 3065114 R 536232 CDS YP_002805207.1 226950116 7765468 complement(3066439..3066969) 1 NC_012563.1 hypothetical protein 3066969 7765468 CLM_3070 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805207.1 3066439 R 536232 CDS YP_002805208.1 226950117 7765854 complement(3066993..3068171) 1 NC_012563.1 identified by match to protein family HMM PF00534; group 1 glycosyl transferase family 3068171 7765854 CLM_3071 Clostridium botulinum A2 str. Kyoto group 1 glycosyl transferase family YP_002805208.1 3066993 R 536232 CDS YP_002805209.1 226950118 7765643 complement(3068208..3069995) 1 NC_012563.1 TPR/glycosyl transferase domain-containing protein 3069995 7765643 CLM_3072 Clostridium botulinum A2 str. Kyoto TPR/glycosyl transferase domain-containing protein YP_002805209.1 3068208 R 536232 CDS YP_002805210.1 226950119 7766269 complement(3070111..3070626) 1 NC_012563.1 hypothetical protein 3070626 7766269 CLM_3073 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805210.1 3070111 R 536232 CDS YP_002805211.1 226950120 7766960 complement(3070627..3072075) 1 NC_012563.1 hypothetical protein 3072075 7766960 CLM_3074 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805211.1 3070627 R 536232 CDS YP_002805212.1 226950121 7768060 complement(3072113..3072829) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3072829 7768060 CLM_3075 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805212.1 3072113 R 536232 CDS YP_002805213.1 226950122 7766128 complement(3072981..3074294) 1 NC_012563.1 hypothetical protein 3074294 7766128 CLM_3076 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805213.1 3072981 R 536232 CDS YP_002805214.1 226950123 7766817 complement(3074312..3075496) 1 NC_012563.1 identified by match to protein family HMM PF00534; group 1 glycosyl transferase family 3075496 7766817 CLM_3077 Clostridium botulinum A2 str. Kyoto group 1 glycosyl transferase family YP_002805214.1 3074312 R 536232 CDS YP_002805215.1 226950124 7767459 complement(3075529..3076866) 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 3076866 7767459 CLM_3078 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002805215.1 3075529 R 536232 CDS YP_002805216.1 226950125 7764598 complement(3076925..3078235) 1 NC_012563.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; GDP-mannose 6-dehydrogenase 3078235 7764598 CLM_3079 Clostridium botulinum A2 str. Kyoto GDP-mannose 6-dehydrogenase YP_002805216.1 3076925 R 536232 CDS YP_002805217.1 226950126 7767817 complement(3078273..3079748) 1 NC_012563.1 hypothetical protein 3079748 7767817 CLM_3080 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805217.1 3078273 R 536232 CDS YP_002805218.1 226950127 7766936 complement(3079789..3080919) 1 NC_012563.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 3080919 7766936 CLM_3081 Clostridium botulinum A2 str. Kyoto TDP-4-oxo-6-deoxy-D-glucose transaminase YP_002805218.1 3079789 R 536232 CDS YP_002805219.1 226950128 7764635 complement(3080906..3081637) 1 NC_012563.1 identified by match to protein family HMM PF08889; hypothetical protein 3081637 7764635 CLM_3082 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805219.1 3080906 R 536232 CDS YP_002805220.1 226950129 7764787 complement(3081662..3082633) 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM 3082633 7764787 CLM_3083 Clostridium botulinum A2 str. Kyoto radical SAM YP_002805220.1 3081662 R 536232 CDS YP_002805221.1 226950130 7766200 complement(3082665..3083522) 1 NC_012563.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 3083522 rfbA 7766200 rfbA Clostridium botulinum A2 str. Kyoto glucose-1-phosphate thymidylyltransferase YP_002805221.1 3082665 R 536232 CDS YP_002805222.1 226950131 7767384 complement(3083548..3084612) 1 NC_012563.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 3084612 rfbB 7767384 rfbB Clostridium botulinum A2 str. Kyoto dTDP-glucose 4,6-dehydratase YP_002805222.1 3083548 R 536232 CDS YP_002805223.1 226950132 7764955 complement(3084672..3085724) 1 NC_012563.1 identified by match to protein family HMM PF03102; match to protein family HMM PF08666; match to protein family HMM TIGR03586; pseudaminic acid synthase 3085724 pseI 7764955 pseI Clostridium botulinum A2 str. Kyoto pseudaminic acid synthase YP_002805223.1 3084672 R 536232 CDS YP_002805224.1 226950133 7765814 complement(3085866..3086621) 1 NC_012563.1 identified by match to protein family HMM PF02348; polysaccharide biosynthesis protein 3086621 7765814 CLM_3087 Clostridium botulinum A2 str. Kyoto polysaccharide biosynthesis protein YP_002805224.1 3085866 R 536232 CDS YP_002805225.1 226950134 7766185 complement(3086744..3087415) 1 NC_012563.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; HAD superfamily hydrolase 3087415 7766185 CLM_3088 Clostridium botulinum A2 str. Kyoto HAD superfamily hydrolase YP_002805225.1 3086744 R 536232 CDS YP_002805226.1 226950135 7767975 complement(3087455..3088483) 1 NC_012563.1 undetermined role; similar to CarB protein but much smaller; carbamoyl phosphate synthase-like protein 3088483 7767975 CLM_3089 Clostridium botulinum A2 str. Kyoto carbamoyl phosphate synthase-like protein YP_002805226.1 3087455 R 536232 CDS YP_002805227.1 226950136 7764506 complement(3088704..3089768) 1 NC_012563.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; NAD-dependent epimerase/dehydratase family protein 3089768 7764506 CLM_3090 Clostridium botulinum A2 str. Kyoto NAD-dependent epimerase/dehydratase family protein YP_002805227.1 3088704 R 536232 CDS YP_002805228.1 226950137 7767167 complement(3089888..3090913) 1 NC_012563.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; exopolysaccharide biosynthesis protein 3090913 7767167 CLM_3091 Clostridium botulinum A2 str. Kyoto exopolysaccharide biosynthesis protein YP_002805228.1 3089888 R 536232 CDS YP_002805229.1 226950138 7767871 complement(3090954..3092375) 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF00535; match to protein family HMM PF07719; group 2 family glycosyl transferase 3092375 7767871 CLM_3092 Clostridium botulinum A2 str. Kyoto group 2 family glycosyl transferase YP_002805229.1 3090954 R 536232 CDS YP_002805230.1 226950139 7766541 complement(3092384..3092731) 1 NC_012563.1 hypothetical protein 3092731 7766541 CLM_3093 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805230.1 3092384 R 536232 CDS YP_002805231.1 226950140 7765690 complement(3092735..3094438) 1 NC_012563.1 identified by match to protein family HMM PF01973; hypothetical protein 3094438 7765690 CLM_3094 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805231.1 3092735 R 536232 CDS YP_002805232.1 226950141 7764884 complement(3094463..3096388) 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF00535; group 2 family glycosyl transferase 3096388 7764884 CLM_3095 Clostridium botulinum A2 str. Kyoto group 2 family glycosyl transferase YP_002805232.1 3094463 R 536232 CDS YP_002805233.1 226950142 7767810 complement(3096587..3097414) 1 NC_012563.1 identified by match to protein family HMM PF00669; match to protein family HMM PF00700; flagellin 3097414 7767810 CLM_3096 Clostridium botulinum A2 str. Kyoto flagellin YP_002805233.1 3096587 R 536232 CDS YP_002805234.1 226950143 7766947 complement(3097628..3098455) 1 NC_012563.1 identified by match to protein family HMM PF00669; match to protein family HMM PF00700; flagellin 3098455 7766947 CLM_3097 Clostridium botulinum A2 str. Kyoto flagellin YP_002805234.1 3097628 R 536232 CDS YP_002805235.1 226950144 7765496 complement(3098605..3098946) 1 NC_012563.1 hypothetical protein 3098946 7765496 CLM_3098 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805235.1 3098605 R 536232 CDS YP_002805236.1 226950145 7764634 complement(3098973..3101408) 1 NC_012563.1 identified by match to protein family HMM PF02465; match to protein family HMM PF07195; flagellar hook-associated protein 2 3101408 fliD 7764634 fliD Clostridium botulinum A2 str. Kyoto flagellar hook-associated protein 2 YP_002805236.1 3098973 R 536232 CDS YP_002805237.1 226950146 7766367 complement(3101462..3101851) 1 NC_012563.1 identified by match to protein family HMM PF02561; match to protein family HMM TIGR00208; flagellar protein FliS 3101851 fliS 7766367 fliS Clostridium botulinum A2 str. Kyoto flagellar protein FliS YP_002805237.1 3101462 R 536232 CDS YP_002805238.1 226950147 7765685 complement(3101888..3102187) 1 NC_012563.1 hypothetical protein 3102187 7765685 CLM_3101 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805238.1 3101888 R 536232 CDS YP_002805239.1 226950148 7764799 complement(3102242..3102598) 1 NC_012563.1 identified by match to protein family HMM PF03646; flaG family protein 3102598 7764799 CLM_3102 Clostridium botulinum A2 str. Kyoto flaG family protein YP_002805239.1 3102242 R 536232 CDS YP_002805240.1 226950149 7767514 complement(3102614..3102832) 1 NC_012563.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 3102832 csrA 7767514 csrA Clostridium botulinum A2 str. Kyoto carbon storage regulator YP_002805240.1 3102614 R 536232 CDS YP_002805241.1 226950150 7766567 complement(3102832..3103263) 1 NC_012563.1 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 3103263 fliW 7766567 fliW Clostridium botulinum A2 str. Kyoto flagellar assembly protein FliW YP_002805241.1 3102832 R 536232 CDS YP_002805242.1 226950151 7765174 complement(3103352..3104314) 1 NC_012563.1 identified by match to protein family HMM PF00669; match to protein family HMM TIGR02550; flagellar hook-associated protein 3 3104314 flgL 7765174 flgL Clostridium botulinum A2 str. Kyoto flagellar hook-associated protein 3 YP_002805242.1 3103352 R 536232 CDS YP_002805243.1 226950152 7764336 complement(3104332..3106200) 1 NC_012563.1 identified by match to protein family HMM PF00460; match to protein family HMM PF06429; match to protein family HMM TIGR02492; flagellar hook-associated protein FlgK 3106200 flgK 7764336 flgK Clostridium botulinum A2 str. Kyoto flagellar hook-associated protein FlgK YP_002805243.1 3104332 R 536232 CDS YP_002805244.1 226950153 7764946 complement(3106489..3106893) 1 NC_012563.1 identified by match to protein family HMM PF05130; flgN family protein 3106893 7764946 CLM_3107 Clostridium botulinum A2 str. Kyoto flgN family protein YP_002805244.1 3106489 R 536232 CDS YP_002805245.1 226950154 7768042 complement(3106893..3107174) 1 NC_012563.1 identified by match to protein family HMM PF04316; regulator of flagellin synthesis FlgM 3107174 7768042 CLM_3108 Clostridium botulinum A2 str. Kyoto regulator of flagellin synthesis FlgM YP_002805245.1 3106893 R 536232 CDS YP_002805246.1 226950155 7766918 complement(3107671..3108831) 1 NC_012563.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein 3108831 fliN 7766918 fliN Clostridium botulinum A2 str. Kyoto flagellar motor switch protein YP_002805246.1 3107671 R 536232 CDS YP_002805247.1 226950156 7765877 complement(3108824..3109819) 1 NC_012563.1 identified by match to protein family HMM PF01052; match to protein family HMM PF02154; match to protein family HMM TIGR01397; flagellar motor switch protein FliM 3109819 fliM 7765877 fliM Clostridium botulinum A2 str. Kyoto flagellar motor switch protein FliM YP_002805247.1 3108824 R 536232 CDS YP_002805248.1 226950157 7765939 complement(3109847..3110242) 1 NC_012563.1 identified by match to protein family HMM PF01584; putative chemotaxis protein CheW 3110242 7765939 CLM_3111 Clostridium botulinum A2 str. Kyoto putative chemotaxis protein CheW YP_002805248.1 3109847 R 536232 CDS YP_002805249.1 226950158 7765136 complement(3110342..3110701) 1 NC_012563.1 identified by match to protein family HMM PF00072; chemotaxis protein CheY 3110701 cheY 7765136 cheY Clostridium botulinum A2 str. Kyoto chemotaxis protein CheY YP_002805249.1 3110342 R 536232 CDS YP_002805250.1 226950159 7767848 complement(3110729..3111328) 1 NC_012563.1 identified by match to protein family HMM PF04509; chemotaxis protein CheC 3111328 cheC 7767848 cheC Clostridium botulinum A2 str. Kyoto chemotaxis protein CheC YP_002805250.1 3110729 R 536232 CDS YP_002805251.1 226950160 7766412 complement(3111354..3113429) 1 NC_012563.1 identified by match to protein family HMM PF01584; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF02895; match to protein family HMM PF07194; chemotaxis protein CheA 3113429 cheA 7766412 cheA Clostridium botulinum A2 str. Kyoto chemotaxis protein CheA YP_002805251.1 3111354 R 536232 CDS YP_002805252.1 226950161 7765577 complement(3113442..3114212) 1 NC_012563.1 identified by match to protein family HMM PF01739; match to protein family HMM PF03705; chemotaxis protein methyltransferase CheR 3114212 cheR 7765577 cheR Clostridium botulinum A2 str. Kyoto chemotaxis protein methyltransferase CheR YP_002805252.1 3113442 R 536232 CDS YP_002805253.1 226950162 7764207 complement(3114227..3115291) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF01339; protein-glutamate methylesterase CheB 3115291 cheB 7764207 cheB Clostridium botulinum A2 str. Kyoto protein-glutamate methylesterase CheB YP_002805253.1 3114227 R 536232 CDS YP_002805254.1 226950163 7767333 complement(3115314..3115802) 1 NC_012563.1 catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors; chemoreceptor glutamine deamidase CheD 3115802 cheD 7767333 cheD Clostridium botulinum A2 str. Kyoto chemoreceptor glutamine deamidase CheD YP_002805254.1 3115314 R 536232 CDS YP_002805255.1 226950164 7765984 complement(3115819..3116265) 1 NC_012563.1 identified by match to protein family HMM PF01584; chemotaxis protein CheW 3116265 cheW 7765984 cheW Clostridium botulinum A2 str. Kyoto chemotaxis protein CheW YP_002805255.1 3115819 R 536232 CDS YP_002805256.1 226950165 7765114 complement(3116281..3118314) 1 NC_012563.1 identified by match to protein family HMM PF03961; hypothetical protein 3118314 7765114 CLM_3119 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805256.1 3116281 R 536232 CDS YP_002805257.1 226950166 7767566 complement(3118567..3120522) 1 NC_012563.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00830; PTS system glucose family transporter subunit IIABC 3120522 7767566 CLM_3120 Clostridium botulinum A2 str. Kyoto PTS system glucose family transporter subunit IIABC YP_002805257.1 3118567 R 536232 CDS YP_002805258.1 226950167 7766781 complement(3120605..3121432) 1 NC_012563.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123; transcriptional antiterminator, BglG family 3121432 7766781 CLM_3121 Clostridium botulinum A2 str. Kyoto transcriptional antiterminator, BglG family YP_002805258.1 3120605 R 536232 CDS YP_002805259.1 226950168 7768112 complement(3121681..3122514) 1 NC_012563.1 identified by match to protein family HMM PF01063; putative branched-chain amino acid aminotransferase 3122514 7768112 CLM_3122 Clostridium botulinum A2 str. Kyoto putative branched-chain amino acid aminotransferase YP_002805259.1 3121681 R 536232 CDS YP_002805260.1 226950169 7764917 complement(3122641..3123282) 1 NC_012563.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490; HAD superfamily hydrolase 3123282 7764917 CLM_3123 Clostridium botulinum A2 str. Kyoto HAD superfamily hydrolase YP_002805260.1 3122641 R 536232 CDS YP_002805261.1 226950170 7766322 complement(3123539..3123934) 1 NC_012563.1 hypothetical protein 3123934 7766322 CLM_3124 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805261.1 3123539 R 536232 CDS YP_002805262.1 226950171 7767177 complement(3124195..3124311) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3124311 7767177 CLM_3125 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805262.1 3124195 R 536232 CDS YP_002805263.1 226950172 7764695 complement(3124577..3128155) 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176; pyruvate ferredoxin oxidoreductase 3128155 7764695 CLM_3126 Clostridium botulinum A2 str. Kyoto pyruvate ferredoxin oxidoreductase YP_002805263.1 3124577 R 536232 CDS YP_002805264.1 226950173 7765808 complement(3128786..3129850) 1 NC_012563.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 3129850 murG 7765808 murG Clostridium botulinum A2 str. Kyoto UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_002805264.1 3128786 R 536232 CDS YP_002805265.1 226950174 7767603 3130175..3130339 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3130339 7767603 CLM_3128 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805265.1 3130175 D 536232 CDS YP_002805266.1 226950175 7767587 complement(3130453..3132561) 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensory box histidine kinase 3132561 7767587 CLM_3129 Clostridium botulinum A2 str. Kyoto sensory box histidine kinase YP_002805266.1 3130453 R 536232 CDS YP_002805267.1 226950176 7764460 complement(3133792..3135573) 1 NC_012563.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644; single-stranded-DNA-specific exonuclease RecJ 3135573 recJ 7764460 recJ Clostridium botulinum A2 str. Kyoto single-stranded-DNA-specific exonuclease RecJ YP_002805267.1 3133792 R 536232 CDS YP_002805268.1 226950177 7767107 3135764..3136582 1 NC_012563.1 identified by match to protein family HMM PF01261; AP endonuclease 3136582 7767107 CLM_3131 Clostridium botulinum A2 str. Kyoto AP endonuclease YP_002805268.1 3135764 D 536232 CDS YP_002805269.1 226950178 7768001 complement(3136866..3138269) 1 NC_012563.1 identified by match to protein family HMM PF01436; NHL repeat-containing protein 3138269 7768001 CLM_3132 Clostridium botulinum A2 str. Kyoto NHL repeat-containing protein YP_002805269.1 3136866 R 536232 CDS YP_002805270.1 226950179 7767191 complement(3138858..3140075) 1 NC_012563.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16 family 3140075 7767191 CLM_3133 Clostridium botulinum A2 str. Kyoto peptidase, M16 family YP_002805270.1 3138858 R 536232 CDS YP_002805271.1 226950180 7764264 3140455..3140865 1 NC_012563.1 hypothetical protein 3140865 7764264 CLM_3134 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805271.1 3140455 D 536232 CDS YP_002805272.1 226950181 7765635 3140933..3141484 1 NC_012563.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383; DJ-1 family protein 3141484 7765635 CLM_3135 Clostridium botulinum A2 str. Kyoto DJ-1 family protein YP_002805272.1 3140933 D 536232 CDS YP_002805273.1 226950182 7766340 complement(3141697..3142260) 1 NC_012563.1 identified by match to protein family HMM PF04309; glycerol uptake operon antiterminator regulatory protein 3142260 glpP 7766340 glpP Clostridium botulinum A2 str. Kyoto glycerol uptake operon antiterminator regulatory protein YP_002805273.1 3141697 R 536232 CDS YP_002805274.1 226950183 7767164 complement(3142309..3145179) 1 NC_012563.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3145179 7767164 CLM_3137 Clostridium botulinum A2 str. Kyoto DNA topoisomerase IV subunit A YP_002805274.1 3142309 R 536232 CDS YP_002805275.1 226950184 7764833 complement(3145253..3147208) 1 NC_012563.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3147208 7764833 CLM_3138 Clostridium botulinum A2 str. Kyoto DNA topoisomerase IV subunit B YP_002805275.1 3145253 R 536232 CDS YP_002805276.1 226950185 7765451 complement(3147575..3147952) 1 NC_012563.1 hypothetical protein 3147952 7765451 CLM_3139 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805276.1 3147575 R 536232 CDS YP_002805277.1 226950186 7767143 3148139..3149311 1 NC_012563.1 identified by match to protein family HMM PF00999; CPA2 family transporter 3149311 7767143 CLM_3140 Clostridium botulinum A2 str. Kyoto CPA2 family transporter YP_002805277.1 3148139 D 536232 CDS YP_002805278.1 226950187 7766770 3149324..3149674 1 NC_012563.1 hypothetical protein 3149674 7766770 CLM_3141 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805278.1 3149324 D 536232 CDS YP_002805279.1 226950188 7766127 3150114..3150350 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3150350 7766127 CLM_3142 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805279.1 3150114 D 536232 CDS YP_002805280.1 226950189 7764633 3150370..3151263 1 NC_012563.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 3151263 7764633 CLM_3143 Clostridium botulinum A2 str. Kyoto polysaccharide deacetylase family protein YP_002805280.1 3150370 D 536232 CDS YP_002805281.1 226950190 7767457 complement(3151345..3152634) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3152634 7767457 CLM_3144 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805281.1 3151345 R 536232 CDS YP_002805282.1 226950191 7766309 complement(3152672..3153652) 1 NC_012563.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase 3153652 galE 7766309 galE Clostridium botulinum A2 str. Kyoto UDP-glucose 4-epimerase YP_002805282.1 3152672 R 536232 CDS YP_002805283.1 226950192 7765191 complement(3153999..3154415) 1 NC_012563.1 identified by match to protein family HMM PF00258; match to protein family HMM TIGR01753; flavodoxin 3154415 7765191 CLM_3146 Clostridium botulinum A2 str. Kyoto flavodoxin YP_002805283.1 3153999 R 536232 CDS YP_002805284.1 226950193 7766099 complement(3154683..3156104) 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; MATE efflux family protein 3156104 7766099 CLM_3147 Clostridium botulinum A2 str. Kyoto MATE efflux family protein YP_002805284.1 3154683 R 536232 CDS YP_002805285.1 226950194 7764992 complement(3156725..3158791) 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 3158791 7764992 CLM_3148 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002805285.1 3156725 R 536232 CDS YP_002805286.1 226950195 7767545 3159190..3160227 1 NC_012563.1 identified by match to protein family HMM PF02016; LD-carboxypeptidase family protein 3160227 7767545 CLM_3149 Clostridium botulinum A2 str. Kyoto LD-carboxypeptidase family protein YP_002805286.1 3159190 D 536232 CDS YP_002805287.1 226950196 7766454 complement(3160658..3162154) 1 NC_012563.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01311; glycerol kinase 3162154 glpK 7766454 glpK Clostridium botulinum A2 str. Kyoto glycerol kinase YP_002805287.1 3160658 R 536232 CDS YP_002805288.1 226950197 7766804 complement(3162407..3163111) 1 NC_012563.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; glycerol uptake facilitator protein 3163111 7766804 CLM_3151 Clostridium botulinum A2 str. Kyoto glycerol uptake facilitator protein YP_002805288.1 3162407 R 536232 CDS YP_002805289.1 226950198 7765424 3163645..3163965 1 NC_012563.1 identified by match to protein family HMM PF01906; hypothetical protein 3163965 7765424 CLM_3152 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805289.1 3163645 D 536232 CDS YP_002805290.1 226950199 7765664 complement(3164077..3164775) 1 NC_012563.1 identified by match to protein family HMM PF04892; VanZ family membrane protein 3164775 7765664 CLM_3153 Clostridium botulinum A2 str. Kyoto VanZ family membrane protein YP_002805290.1 3164077 R 536232 CDS YP_002805291.1 226950200 7764851 complement(3164907..3165983) 1 NC_012563.1 ABC transporter permease 3165983 7764851 CLM_3154 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002805291.1 3164907 R 536232 CDS YP_002805292.1 226950201 7767931 complement(3165967..3166863) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3166863 7767931 CLM_3155 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002805292.1 3165967 R 536232 CDS YP_002805293.1 226950202 7765314 complement(3166869..3167249) 1 NC_012563.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 3167249 7765314 CLM_3156 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002805293.1 3166869 R 536232 CDS YP_002805294.1 226950203 7765402 complement(3167423..3167938) 1 NC_012563.1 identified by match to protein family HMM PF04892; VanZ family membrane protein 3167938 7765402 CLM_3157 Clostridium botulinum A2 str. Kyoto VanZ family membrane protein YP_002805294.1 3167423 R 536232 CDS YP_002805295.1 226950204 7764306 3168369..3170081 1 NC_012563.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 3170081 hcp 7764306 hcp Clostridium botulinum A2 str. Kyoto hydroxylamine reductase YP_002805295.1 3168369 D 536232 CDS YP_002805296.1 226950205 7767636 3170945..3171535 1 NC_012563.1 membrane-spanning protein 3171535 7767636 CLM_3159 Clostridium botulinum A2 str. Kyoto membrane-spanning protein YP_002805296.1 3170945 D 536232 CDS YP_002805297.1 226950206 7766516 3171840..3173072 1 NC_012563.1 identified by match to protein family HMM PF02073; aminopeptidase II 3173072 7766516 CLM_3160 Clostridium botulinum A2 str. Kyoto aminopeptidase II YP_002805297.1 3171840 D 536232 CDS YP_002805298.1 226950207 7766892 complement(3173444..3174577) 1 NC_012563.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887; spore germination protein, GerAC 3174577 gerAC 7766892 gerAC Clostridium botulinum A2 str. Kyoto spore germination protein, GerAC YP_002805298.1 3173444 R 536232 CDS YP_002805299.1 226950208 7766914 complement(3174546..3175664) 1 NC_012563.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912; spore germination protein 3175664 7766914 CLM_3162 Clostridium botulinum A2 str. Kyoto spore germination protein YP_002805299.1 3174546 R 536232 CDS YP_002805300.1 226950209 7768041 complement(3175645..3177141) 1 NC_012563.1 identified by match to protein family HMM PF03323; spore germination protein, GerAA 3177141 gerAA 7768041 gerAA Clostridium botulinum A2 str. Kyoto spore germination protein, GerAA YP_002805300.1 3175645 R 536232 CDS YP_002805301.1 226950210 7764968 complement(3177430..3177639) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3177639 7764968 CLM_3164 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805301.1 3177430 R 536232 CDS YP_002805302.1 226950211 7766305 complement(3178025..3178756) 1 NC_012563.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 3178756 7766305 CLM_3165 Clostridium botulinum A2 str. Kyoto polysaccharide deacetylase family protein YP_002805302.1 3178025 R 536232 CDS YP_002805303.1 226950212 7764583 complement(3178975..3180549) 1 NC_012563.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; DEAD/DEAH box family ATP-dependent RNA helicase 3180549 7764583 CLM_3166 Clostridium botulinum A2 str. Kyoto DEAD/DEAH box family ATP-dependent RNA helicase YP_002805303.1 3178975 R 536232 CDS YP_002805304.1 226950213 7765036 complement(3180626..3180793) 1 NC_012563.1 hypothetical protein 3180793 7765036 CLM_3167 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805304.1 3180626 R 536232 CDS YP_002805305.1 226950214 7766147 3181225..3181617 1 NC_012563.1 hypothetical protein 3181617 7766147 CLM_3168 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805305.1 3181225 D 536232 CDS YP_002805306.1 226950215 7766726 complement(3181706..3183400) 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis protein 3183400 7766726 CLM_3169 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002805306.1 3181706 R 536232 CDS YP_002805307.1 226950216 7764724 complement(3183596..3184006) 1 NC_012563.1 identified by match to protein family HMM PF00582; universal stress protein family protein 3184006 7764724 CLM_3170 Clostridium botulinum A2 str. Kyoto universal stress protein family protein YP_002805307.1 3183596 R 536232 CDS YP_002805308.1 226950217 7767348 3184317..3184496 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3184496 7767348 CLM_3171 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805308.1 3184317 D 536232 CDS YP_002805309.1 226950218 7766218 3184639..3185280 1 NC_012563.1 identified by match to protein family HMM PF00037; iron-sulfur cluster-binding protein 3185280 7766218 CLM_3172 Clostridium botulinum A2 str. Kyoto iron-sulfur cluster-binding protein YP_002805309.1 3184639 D 536232 CDS YP_002805310.1 226950219 7766122 complement(3185530..3186447) 1 NC_012563.1 catalyzes the formation of glutamate from glutamine; glutaminase 3186447 7766122 CLM_3173 Clostridium botulinum A2 str. Kyoto glutaminase YP_002805310.1 3185530 R 536232 CDS YP_002805311.1 226950220 7767889 complement(3186842..3187867) 1 NC_012563.1 identified by match to protein family HMM PF06725; hypothetical protein 3187867 7767889 CLM_3174 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805311.1 3186842 R 536232 CDS YP_002805312.1 226950221 7766925 complement(3188245..3190305) 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 3190305 7766925 CLM_3175 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002805312.1 3188245 R 536232 CDS YP_002805313.1 226950222 7766608 complement(3190824..3191624) 1 NC_012563.1 hypothetical protein 3191624 7766608 CLM_3176 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805313.1 3190824 R 536232 CDS YP_002805314.1 226950223 7764792 complement(3191969..3192997) 1 NC_012563.1 identified by match to protein family HMM PF00268; ribonucleoside-diphosphate reductase subunit beta 3192997 nrdB 7764792 nrdB Clostridium botulinum A2 str. Kyoto ribonucleoside-diphosphate reductase subunit beta YP_002805314.1 3191969 R 536232 CDS YP_002805315.1 226950224 7767463 complement(3193193..3195484) 1 NC_012563.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3195484 nrdA 7767463 nrdA Clostridium botulinum A2 str. Kyoto ribonucleotide-diphosphate reductase subunit alpha YP_002805315.1 3193193 R 536232 CDS YP_002805316.1 226950225 7766543 3196079..3197200 1 NC_012563.1 hypothetical protein 3197200 7766543 CLM_3179 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805316.1 3196079 D 536232 CDS YP_002805317.1 226950226 7766110 3197437..3198288 1 NC_012563.1 hypothetical protein 3198288 7766110 CLM_3180 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805317.1 3197437 D 536232 CDS YP_002805318.1 226950227 7767836 complement(3198448..3199497) 1 NC_012563.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 3199497 dinB 7767836 dinB Clostridium botulinum A2 str. Kyoto DNA polymerase IV YP_002805318.1 3198448 R 536232 CDS YP_002805319.1 226950228 7767190 complement(3199944..3201179) 1 NC_012563.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 3201179 7767190 CLM_3182 Clostridium botulinum A2 str. Kyoto dihydropyrimidine dehydrogenase YP_002805319.1 3199944 R 536232 CDS YP_002805320.1 226950229 7764368 complement(3201179..3202495) 1 NC_012563.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase family protein 3202495 7764368 CLM_3183 Clostridium botulinum A2 str. Kyoto pyridine nucleotide-disulfide oxidoreductase family protein YP_002805320.1 3201179 R 536232 CDS YP_002805321.1 226950230 7765912 complement(3202943..3203491) 1 NC_012563.1 identified by match to protein family HMM PF00156; pyrimidine operon regulatory protein/uracil phosphoribosyltransferase 3203491 pyrR 7765912 pyrR Clostridium botulinum A2 str. Kyoto pyrimidine operon regulatory protein/uracil phosphoribosyltransferase YP_002805321.1 3202943 R 536232 CDS YP_002805322.1 226950231 7766238 complement(3203819..3204874) 1 NC_012563.1 identified by match to protein family HMM PF02698; hypothetical protein 3204874 7766238 CLM_3185 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805322.1 3203819 R 536232 CDS YP_002805323.1 226950232 7767536 complement(3205642..3206061) 1 NC_012563.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03965; MarR family transcriptional regulator 3206061 7767536 CLM_3186 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002805323.1 3205642 R 536232 CDS YP_002805324.1 226950233 7764394 complement(3206079..3208337) 1 NC_012563.1 identified by match to protein family HMM PF00005; putative excinuclease ABC subunit A 3208337 7764394 CLM_3187 Clostridium botulinum A2 str. Kyoto putative excinuclease ABC subunit A YP_002805324.1 3206079 R 536232 CDS YP_002805325.1 226950234 7764798 3208705..3209013 1 NC_012563.1 hypothetical protein 3209013 7764798 CLM_3188 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805325.1 3208705 D 536232 CDS YP_002805326.1 226950235 7765663 complement(3209125..3209652) 1 NC_012563.1 identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258; 2'-5' RNA ligase 3209652 ligT 7765663 ligT Clostridium botulinum A2 str. Kyoto 2'-5' RNA ligase YP_002805326.1 3209125 R 536232 CDS YP_002805327.1 226950236 7766248 complement(3209825..3210223) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3210223 7766248 CLM_3190 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805327.1 3209825 R 536232 CDS YP_002805328.1 226950237 7764814 complement(3210796..3212508) 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; methyl-accepting chemotaxis protein 3212508 7764814 CLM_3191 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002805328.1 3210796 R 536232 CDS YP_002805329.1 226950238 7765715 complement(3213229..3213666) 1 NC_012563.1 identified by match to protein family HMM PF00293; MutT/NUDIX family protein 3213666 7765715 CLM_3193 Clostridium botulinum A2 str. Kyoto MutT/NUDIX family protein YP_002805329.1 3213229 R 536232 CDS YP_002805330.1 226950239 7767099 3214290..3214757 1 NC_012563.1 identified by match to protein family HMM PF01475; Fur family transcriptional regulator 3214757 7767099 CLM_3194 Clostridium botulinum A2 str. Kyoto Fur family transcriptional regulator YP_002805330.1 3214290 D 536232 CDS YP_002805331.1 226950240 7768015 3214889..3216898 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3216898 7768015 CLM_3195 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805331.1 3214889 D 536232 CDS YP_002805332.1 226950241 7767363 complement(3216985..3219204) 1 NC_012563.1 identified by match to protein family HMM PF00704; glycosyl hydrolase, family 18 3219204 7767363 CLM_3196 Clostridium botulinum A2 str. Kyoto glycosyl hydrolase, family 18 YP_002805332.1 3216985 R 536232 CDS YP_002805333.1 226950242 7764600 complement(3219433..3220167) 1 NC_012563.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 3220167 nagB 7764600 nagB Clostridium botulinum A2 str. Kyoto glucosamine-6-phosphate deaminase YP_002805333.1 3219433 R 536232 CDS YP_002805334.1 226950243 7765409 complement(3220250..3221392) 1 NC_012563.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 3221392 nagA 7765409 nagA Clostridium botulinum A2 str. Kyoto N-acetylglucosamine-6-phosphate deacetylase YP_002805334.1 3220250 R 536232 CDS YP_002805335.1 226950244 7766785 complement(3221553..3222287) 1 NC_012563.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 3222287 7766785 CLM_3199 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002805335.1 3221553 R 536232 CDS YP_002805336.1 226950245 7767774 3222582..3223439 1 NC_012563.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123; transcriptional antiterminator, BglG family 3223439 7767774 CLM_3200 Clostridium botulinum A2 str. Kyoto transcriptional antiterminator, BglG family YP_002805336.1 3222582 D 536232 CDS YP_002805337.1 226950246 7765102 complement(3223659..3224138) 1 NC_012563.1 identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830; PTS system glucose subfamily transporter subunit IIA 3224138 ptbA 7765102 ptbA Clostridium botulinum A2 str. Kyoto PTS system glucose subfamily transporter subunit IIA YP_002805337.1 3223659 R 536232 CDS YP_002805338.1 226950247 7765187 3224832..3226274 1 NC_012563.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01998; PTS system N-acetylglucosamine-specific transporter subunit IIBC 3226274 nagE 7765187 nagE Clostridium botulinum A2 str. Kyoto PTS system N-acetylglucosamine-specific transporter subunit IIBC YP_002805338.1 3224832 D 536232 CDS YP_002805339.1 226950248 7764620 3226753..3228123 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; MATE efflux family protein 3228123 7764620 CLM_3203 Clostridium botulinum A2 str. Kyoto MATE efflux family protein YP_002805339.1 3226753 D 536232 CDS YP_002805340.1 226950249 7766103 complement(3228258..3229178) 1 NC_012563.1 identified by match to protein family HMM PF01458; SufBD protein 3229178 7766103 CLM_3204 Clostridium botulinum A2 str. Kyoto SufBD protein YP_002805340.1 3228258 R 536232 CDS YP_002805341.1 226950250 7764829 complement(3229180..3229899) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3229899 7764829 CLM_3205 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002805341.1 3229180 R 536232 CDS YP_002805342.1 226950251 7765714 complement(3229989..3230591) 1 NC_012563.1 hypothetical protein 3230591 7765714 CLM_3206 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805342.1 3229989 R 536232 CDS YP_002805343.1 226950252 7764835 3231137..3231619 1 NC_012563.1 identified by match to protein family HMM PF01475; Fur family transcriptional regulator 3231619 7764835 CLM_3207 Clostridium botulinum A2 str. Kyoto Fur family transcriptional regulator YP_002805343.1 3231137 D 536232 CDS YP_002805344.1 226950253 7767421 complement(3231947..3233341) 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM TIGR00797; MATE efflux family protein 3233341 7767421 CLM_3208 Clostridium botulinum A2 str. Kyoto MATE efflux family protein YP_002805344.1 3231947 R 536232 CDS YP_002805345.1 226950254 7766610 complement(3233590..3234789) 1 NC_012563.1 identified by match to protein family HMM PF00258; match to protein family HMM PF00753; metallo-beta-lactamase family protein/flavodoxin 3234789 7766610 CLM_3209 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein/flavodoxin YP_002805345.1 3233590 R 536232 CDS YP_002805346.1 226950255 7765210 complement(3234848..3236755) 1 NC_012563.1 identified by match to protein family HMM PF00301; match to protein family HMM PF00441; match to protein family HMM PF00766; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase family protein/electron transfer protein 3236755 7765210 CLM_3210 Clostridium botulinum A2 str. Kyoto acyl-CoA dehydrogenase family protein/electron transfer protein YP_002805346.1 3234848 R 536232 CDS YP_002805347.1 226950256 7764376 complement(3237112..3237777) 1 NC_012563.1 identified by match to protein family HMM PF00665; transposase ISLasa6a, IS3 family 3237777 7764376 CLM_3211 Clostridium botulinum A2 str. Kyoto transposase ISLasa6a, IS3 family YP_002805347.1 3237112 R 536232 CDS YP_002805348.1 226950257 7767288 complement(3237999..3238676) 1 NC_012563.1 identified by match to protein family HMM PF01527; transposase 3238676 7767288 CLM_3212 Clostridium botulinum A2 str. Kyoto transposase YP_002805348.1 3237999 R 536232 CDS YP_002805349.1 226950258 7767879 3239599..3240405 1 NC_012563.1 identified by match to protein family HMM PF03609; PTS system sorbose-specific transporter subunit IIc 3240405 7767879 CLM_3215 Clostridium botulinum A2 str. Kyoto PTS system sorbose-specific transporter subunit IIc YP_002805349.1 3239599 D 536232 CDS YP_002805350.1 226950259 7766737 3240392..3241336 1 NC_012563.1 identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828; PTS system mannose/fructose/sorbose family transporter subunit IID 3241336 7766737 CLM_3216 Clostridium botulinum A2 str. Kyoto PTS system mannose/fructose/sorbose family transporter subunit IID YP_002805350.1 3240392 D 536232 CDS YP_002805351.1 226950260 7765620 3241504..3241878 1 NC_012563.1 identified by match to protein family HMM PF06115; hypothetical protein 3241878 7765620 CLM_3217 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805351.1 3241504 D 536232 CDS YP_002805352.1 226950261 7764539 3242454..3243170 1 NC_012563.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02429; CoA-transferase subunit A 3243170 7764539 CLM_3218 Clostridium botulinum A2 str. Kyoto CoA-transferase subunit A YP_002805352.1 3242454 D 536232 CDS YP_002805353.1 226950262 7767349 3243179..3243835 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428; CoA-transferase subunit B 3243835 7767349 CLM_3219 Clostridium botulinum A2 str. Kyoto CoA-transferase subunit B YP_002805353.1 3243179 D 536232 CDS YP_002805354.1 226950263 7764469 complement(3244417..3244986) 1 NC_012563.1 hypothetical protein 3244986 7764469 CLM_3220 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805354.1 3244417 R 536232 CDS YP_002805355.1 226950264 7767376 complement(3245205..3245693) 1 NC_012563.1 identified by match to protein family HMM PF00111; match to protein family HMM PF01799; xanthine dehydrogenase family protein iron-sulfur binding subunit 3245693 7767376 CLM_3221 Clostridium botulinum A2 str. Kyoto xanthine dehydrogenase family protein iron-sulfur binding subunit YP_002805355.1 3245205 R 536232 CDS YP_002805356.1 226950265 7764646 complement(3245698..3246528) 1 NC_012563.1 identified by match to protein family HMM PF00941; xanthine dehydrogenase family protein FAD-binding subunit 3246528 7764646 CLM_3222 Clostridium botulinum A2 str. Kyoto xanthine dehydrogenase family protein FAD-binding subunit YP_002805356.1 3245698 R 536232 CDS YP_002805357.1 226950266 7765327 complement(3246525..3248855) 1 NC_012563.1 identified by match to protein family HMM PF01315; match to protein family HMM PF02738; xanthine dehydrogenase family protein molybdopterin-binding subunit 3248855 7765327 CLM_3223 Clostridium botulinum A2 str. Kyoto xanthine dehydrogenase family protein molybdopterin-binding subunit YP_002805357.1 3246525 R 536232 CDS YP_002805358.1 226950267 7767525 complement(3250308..3251525) 1 NC_012563.1 identified by match to protein family HMM PF00999; CPA2 family transporter 3251525 7767525 CLM_3227 Clostridium botulinum A2 str. Kyoto CPA2 family transporter YP_002805358.1 3250308 R 536232 CDS YP_002805359.1 226950268 7764541 complement(3252643..3253314) 1 NC_012563.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; HAD superfamily hydrolase 3253314 7764541 CLM_3229 Clostridium botulinum A2 str. Kyoto HAD superfamily hydrolase YP_002805359.1 3252643 R 536232 CDS YP_002805360.1 226950269 7764285 complement(3253344..3253604) 1 NC_012563.1 identified by match to protein family HMM PF04994; tfoX domain-containing protein 3253604 7764285 CLM_3230 Clostridium botulinum A2 str. Kyoto tfoX domain-containing protein YP_002805360.1 3253344 R 536232 CDS YP_002805361.1 226950270 7765401 3254033..3254479 1 NC_012563.1 hypothetical protein 3254479 7765401 CLM_3231 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805361.1 3254033 D 536232 CDS YP_002805362.1 226950271 7765654 complement(3254544..3254690) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3254690 7765654 CLM_3232 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805362.1 3254544 R 536232 CDS YP_002805363.1 226950272 7766175 complement(3255396..3255851) 1 NC_012563.1 identified by match to protein family HMM PF01510; prophage LambdaCh01, N-acetylmuramoyl-L-alanine amidase 3255851 7766175 CLM_3233 Clostridium botulinum A2 str. Kyoto prophage LambdaCh01, N-acetylmuramoyl-L-alanine amidase YP_002805363.1 3255396 R 536232 CDS YP_002805364.1 226950273 7764599 complement(3256254..3256475) 1 NC_012563.1 hypothetical protein 3256475 7764599 CLM_3235 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805364.1 3256254 R 536232 CDS YP_002805365.1 226950274 7766802 complement(3256888..3257922) 1 NC_012563.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00048; chloramphenicol/florfenicol resistance protein 3257922 7766802 CLM_3236 Clostridium botulinum A2 str. Kyoto chloramphenicol/florfenicol resistance protein YP_002805365.1 3256888 R 536232 CDS YP_002805366.1 226950275 7765993 complement(3258085..3259563) 1 NC_012563.1 identified by match to protein family HMM PF00005; drug resistance ABC transporter RA2 family, ATP-binding protein 3259563 7765993 CLM_3237 Clostridium botulinum A2 str. Kyoto drug resistance ABC transporter RA2 family, ATP-binding protein YP_002805366.1 3258085 R 536232 CDS YP_002805367.1 226950276 7765152 complement(3260298..3260465) 1 NC_012563.1 hypothetical protein 3260465 7765152 CLM_3238 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805367.1 3260298 R 536232 CDS YP_002805368.1 226950277 7764260 3261678..3262775 1 NC_012563.1 identified by match to protein family HMM PF00144; beta-lactamase 3262775 7764260 CLM_3239 Clostridium botulinum A2 str. Kyoto beta-lactamase YP_002805368.1 3261678 D 536232 CDS YP_002805369.1 226950278 7767200 3263237..3263845 1 NC_012563.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3263845 7767200 CLM_3240 Clostridium botulinum A2 str. Kyoto TetR family transcriptional regulator YP_002805369.1 3263237 D 536232 CDS YP_002805370.1 226950279 7766808 3263968..3264510 1 NC_012563.1 50S ribosomal protein L29 3264510 7766808 CLM_3241 Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L29 YP_002805370.1 3263968 D 536232 CDS YP_002805371.1 226950280 7765521 complement(3264659..3265198) 1 NC_012563.1 conjugative transposon protein 3265198 7765521 CLM_3242 Clostridium botulinum A2 str. Kyoto conjugative transposon protein YP_002805371.1 3264659 R 536232 CDS YP_002805372.1 226950281 7767329 complement(3265188..3265373) 1 NC_012563.1 NLP/P60 family protein 3265373 7767329 CLM_3243 Clostridium botulinum A2 str. Kyoto NLP/P60 family protein YP_002805372.1 3265188 R 536232 CDS YP_002805373.1 226950282 7765950 complement(3265532..3266236) 1 NC_012563.1 hypothetical protein 3266236 7765950 CLM_3244 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805373.1 3265532 R 536232 CDS YP_002805374.1 226950283 7767887 complement(3266283..3267059) 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 3267059 7767887 CLM_3245 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002805374.1 3266283 R 536232 CDS YP_002805375.1 226950284 7767485 complement(3267034..3267216) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3267216 7767485 CLM_3246 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805375.1 3267034 R 536232 CDS YP_002805376.1 226950285 7764206 complement(3267350..3267889) 1 NC_012563.1 identified by match to protein family HMM PF00583; acetyltransferase 3267889 7764206 CLM_3247 Clostridium botulinum A2 str. Kyoto acetyltransferase YP_002805376.1 3267350 R 536232 CDS YP_002805377.1 226950286 7766169 complement(3267903..3268394) 1 NC_012563.1 TetR family transcriptional regulator 3268394 7766169 CLM_3248 Clostridium botulinum A2 str. Kyoto TetR family transcriptional regulator YP_002805377.1 3267903 R 536232 CDS YP_002805378.1 226950287 7767317 complement(3269040..3270305) 1 NC_012563.1 peptidase, family S8/S53 3270305 7767317 CLM_3249 Clostridium botulinum A2 str. Kyoto peptidase, family S8/S53 YP_002805378.1 3269040 R 536232 CDS YP_002805379.1 226950288 7765003 complement(3270321..3270572) 1 NC_012563.1 hypothetical protein 3270572 7765003 CLM_3250 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805379.1 3270321 R 536232 CDS YP_002805380.1 226950289 7766054 complement(3270585..3271715) 1 NC_012563.1 hypothetical protein 3271715 7766054 CLM_3251 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805380.1 3270585 R 536232 CDS YP_002805381.1 226950290 7767473 complement(3271746..3273179) 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 3273179 7767473 CLM_3252 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002805381.1 3271746 R 536232 CDS YP_002805382.1 226950291 7766630 complement(3273245..3273427) 1 NC_012563.1 hypothetical protein 3273427 7766630 CLM_3253 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805382.1 3273245 R 536232 CDS YP_002805383.1 226950292 7765723 complement(3273537..3275234) 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF02463; ABC transporter ATP-binding protein 3275234 7765723 CLM_3254 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002805383.1 3273537 R 536232 CDS YP_002805384.1 226950293 7765669 complement(3275575..3276927) 1 NC_012563.1 identified by match to protein family HMM PF01938; match to protein family HMM PF02475; match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA 3276927 rumA 7765669 rumA Clostridium botulinum A2 str. Kyoto 23S rRNA (uracil-5-)-methyltransferase RumA YP_002805384.1 3275575 R 536232 CDS YP_002805385.1 226950294 7767140 complement(3277214..3277660) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3277660 7767140 CLM_3256 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805385.1 3277214 R 536232 CDS YP_002805386.1 226950295 7767932 3277991..3279850 1 NC_012563.1 identified by match to protein family HMM PF00884; sulfatase family protein 3279850 7767932 CLM_3257 Clostridium botulinum A2 str. Kyoto sulfatase family protein YP_002805386.1 3277991 D 536232 CDS YP_002805387.1 226950296 7767955 3279876..3280628 1 NC_012563.1 identified by match to protein family HMM PF01925; hypothetical protein 3280628 7767955 CLM_3258 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805387.1 3279876 D 536232 CDS YP_002805388.1 226950297 7765298 complement(3281038..3281502) 1 NC_012563.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 3281502 ribH 7765298 ribH Clostridium botulinum A2 str. Kyoto 6,7-dimethyl-8-ribityllumazine synthase YP_002805388.1 3281038 R 536232 CDS YP_002805389.1 226950298 7766813 complement(3281534..3282739) 1 NC_012563.1 identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00505; match to protein family HMM TIGR00506; bifunctional riboflavin biosynthesis protein RibAB 3282739 ribAB 7766813 ribAB Clostridium botulinum A2 str. Kyoto bifunctional riboflavin biosynthesis protein RibAB YP_002805389.1 3281534 R 536232 CDS YP_002805390.1 226950299 7767433 complement(3283047..3283733) 1 NC_012563.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 3283733 ribE 7767433 ribE Clostridium botulinum A2 str. Kyoto riboflavin synthase subunit alpha YP_002805390.1 3283047 R 536232 CDS YP_002805391.1 226950300 7764986 complement(3283714..3284811) 1 NC_012563.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326; riboflavin biosynthesis protein RibD 3284811 ribD 7764986 ribD Clostridium botulinum A2 str. Kyoto riboflavin biosynthesis protein RibD YP_002805391.1 3283714 R 536232 CDS YP_002805392.1 226950301 7766114 complement(3285215..3286651) 1 NC_012563.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893; aminoacyl-histidine dipeptidase 3286651 pepD 7766114 pepD Clostridium botulinum A2 str. Kyoto aminoacyl-histidine dipeptidase YP_002805392.1 3285215 R 536232 CDS YP_002805393.1 226950302 7766718 3287040..3287933 1 NC_012563.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 3287933 7766718 CLM_3265 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002805393.1 3287040 D 536232 CDS YP_002805394.1 226950303 7767621 complement(3288124..3290769) 1 NC_012563.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01524; magnesium-importing ATPase 3290769 mgtA 7767621 mgtA Clostridium botulinum A2 str. Kyoto magnesium-importing ATPase YP_002805394.1 3288124 R 536232 CDS YP_002805395.1 226950304 7766280 complement(3291642..3292046) 1 NC_012563.1 hypothetical protein 3292046 7766280 CLM_3268 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805395.1 3291642 R 536232 CDS YP_002805396.1 226950305 7765366 complement(3292373..3293614) 1 NC_012563.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 3293614 purD 7765366 purD Clostridium botulinum A2 str. Kyoto phosphoribosylamine--glycine ligase YP_002805396.1 3292373 R 536232 CDS YP_002805397.1 226950306 7767241 complement(3293763..3295262) 1 NC_012563.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3295262 purH 7767241 purH Clostridium botulinum A2 str. Kyoto bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002805397.1 3293763 R 536232 CDS YP_002805398.1 226950307 7768127 complement(3295476..3296093) 1 NC_012563.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 3296093 purN 7768127 purN Clostridium botulinum A2 str. Kyoto phosphoribosylglycinamide formyltransferase YP_002805398.1 3295476 R 536232 CDS YP_002805399.1 226950308 7767040 complement(3296220..3297215) 1 NC_012563.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 3297215 purM 7767040 purM Clostridium botulinum A2 str. Kyoto phosphoribosylaminoimidazole synthetase YP_002805399.1 3296220 R 536232 CDS YP_002805400.1 226950309 7766413 complement(3297276..3298724) 1 NC_012563.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 3298724 purF 7766413 purF Clostridium botulinum A2 str. Kyoto amidophosphoribosyltransferase YP_002805400.1 3297276 R 536232 CDS YP_002805401.1 226950310 7765895 complement(3298816..3299520) 1 NC_012563.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 3299520 purC 7765895 purC Clostridium botulinum A2 str. Kyoto phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002805401.1 3298816 R 536232 CDS YP_002805402.1 226950311 7764726 complement(3299520..3299999) 1 NC_012563.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase, catalytic subunit 3299999 purE 7764726 purE Clostridium botulinum A2 str. Kyoto phosphoribosylaminoimidazole carboxylase, catalytic subunit YP_002805402.1 3299520 R 536232 CDS YP_002805403.1 226950312 7767589 complement(3300628..3303183) 1 NC_012563.1 identified by match to protein family HMM PF00111; match to protein family HMM PF01315; match to protein family HMM PF01799; match to protein family HMM PF02738; match to protein family HMM TIGR03311; xanthine dehydrogenase family protein molybdopterin-binding subunit 3303183 7767589 CLM_3277 Clostridium botulinum A2 str. Kyoto xanthine dehydrogenase family protein molybdopterin-binding subunit YP_002805403.1 3300628 R 536232 CDS YP_002805404.1 226950313 7766004 complement(3303558..3304775) 1 NC_012563.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3304775 7766004 CLM_3278 Clostridium botulinum A2 str. Kyoto peptidase YP_002805404.1 3303558 R 536232 CDS YP_002805405.1 226950314 7764492 complement(3304801..3306129) 1 NC_012563.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; putative chlorohydrolase/aminohydrolase 3306129 7764492 CLM_3279 Clostridium botulinum A2 str. Kyoto putative chlorohydrolase/aminohydrolase YP_002805405.1 3304801 R 536232 CDS YP_002805406.1 226950315 7767239 complement(3306160..3309177) 1 NC_012563.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; putative selenate reductase subunit YgfK 3309177 7767239 CLM_3280 Clostridium botulinum A2 str. Kyoto putative selenate reductase subunit YgfK YP_002805406.1 3306160 R 536232 CDS YP_002805407.1 226950316 7767387 complement(3309213..3310409) 1 NC_012563.1 identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR03316; aspartate/ornithine carbamoyltransferase family protein 3310409 7767387 CLM_3281 Clostridium botulinum A2 str. Kyoto aspartate/ornithine carbamoyltransferase family protein YP_002805407.1 3309213 R 536232 CDS YP_002805408.1 226950317 7766234 complement(3310751..3312145) 1 NC_012563.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3312145 hydA 7766234 hydA Clostridium botulinum A2 str. Kyoto phenylhydantoinase YP_002805408.1 3310751 R 536232 CDS YP_002805409.1 226950318 7764684 complement(3312195..3313601) 1 NC_012563.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine/uracil permease family protein 3313601 7764684 CLM_3283 Clostridium botulinum A2 str. Kyoto xanthine/uracil permease family protein YP_002805409.1 3312195 R 536232 CDS YP_002805410.1 226950319 7764542 complement(3313623..3314834) 1 NC_012563.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3314834 dpaL 7764542 dpaL Clostridium botulinum A2 str. Kyoto diaminopropionate ammonia-lyase YP_002805410.1 3313623 R 536232 CDS YP_002805411.1 226950320 7767437 complement(3315118..3316881) 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; sigma-54 dependent transcriptional regulator 3316881 7767437 CLM_3285 Clostridium botulinum A2 str. Kyoto sigma-54 dependent transcriptional regulator YP_002805411.1 3315118 R 536232 CDS YP_002805412.1 226950321 7766604 3317245..3317982 1 NC_012563.1 identified by match to protein family HMM TIGR03172; hypothetical protein 3317982 7766604 CLM_3286 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805412.1 3317245 D 536232 CDS YP_002805413.1 226950322 7765182 3317997..3318611 1 NC_012563.1 identified by match to protein family HMM TIGR03310; molybdenum hydroxylase accessory protein, YgfJ family 3318611 7765182 CLM_3287 Clostridium botulinum A2 str. Kyoto molybdenum hydroxylase accessory protein, YgfJ family YP_002805413.1 3317997 D 536232 CDS YP_002805414.1 226950323 7764875 3318592..3319440 1 NC_012563.1 identified by match to protein family HMM TIGR03309; selenium-dependent molybdenum hydroxylase system protein 3319440 7764875 CLM_3288 Clostridium botulinum A2 str. Kyoto selenium-dependent molybdenum hydroxylase system protein YP_002805414.1 3318592 D 536232 CDS YP_002805415.1 226950324 7765725 3319422..3320231 1 NC_012563.1 identified by match to protein family HMM PF02625; putative xanthine dehydrogenase accessory factor 3320231 7765725 CLM_3289 Clostridium botulinum A2 str. Kyoto putative xanthine dehydrogenase accessory factor YP_002805415.1 3319422 D 536232 CDS YP_002805416.1 226950325 7766648 3320257..3320802 1 NC_012563.1 hypothetical protein 3320802 7766648 CLM_3290 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805416.1 3320257 D 536232 CDS YP_002805417.1 226950326 7767094 3320799..3321767 1 NC_012563.1 identified by match to protein family HMM PF00950; match to protein family HMM PF01032; iron chelate uptake ABC transporter permease 3321767 7767094 CLM_3291 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter permease YP_002805417.1 3320799 D 536232 CDS YP_002805418.1 226950327 7765955 3321764..3322558 1 NC_012563.1 identified by match to protein family HMM PF00005; iron chelate uptake ABC transporter ATP-binding protein 3322558 7765955 CLM_3292 Clostridium botulinum A2 str. Kyoto iron chelate uptake ABC transporter ATP-binding protein YP_002805418.1 3321764 D 536232 CDS YP_002805419.1 226950328 7767396 3322933..3323799 1 NC_012563.1 identified by match to protein family HMM PF01497; putative iron chelate uptake ABC transporter solute-binding protein 3323799 7767396 CLM_3293 Clostridium botulinum A2 str. Kyoto putative iron chelate uptake ABC transporter solute-binding protein YP_002805419.1 3322933 D 536232 CDS YP_002805420.1 226950329 7766206 3323937..3324269 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3324269 7766206 CLM_3294 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805420.1 3323937 D 536232 CDS YP_002805421.1 226950330 7765498 3324397..3324969 1 NC_012563.1 identified by match to protein family HMM PF00657; lipase/acylhydrolase, GDSL family 3324969 7765498 CLM_3295 Clostridium botulinum A2 str. Kyoto lipase/acylhydrolase, GDSL family YP_002805421.1 3324397 D 536232 CDS YP_002805422.1 226950331 7764673 complement(3325080..3325676) 1 NC_012563.1 identified by match to protein family HMM PF02698; hypothetical protein 3325676 7764673 CLM_3296 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805422.1 3325080 R 536232 CDS YP_002805423.1 226950332 7765078 complement(3326250..3327692) 1 NC_012563.1 identified by match to protein family HMM PF00860; xanthine/uracil permease family protein 3327692 7765078 CLM_3297 Clostridium botulinum A2 str. Kyoto xanthine/uracil permease family protein YP_002805423.1 3326250 R 536232 CDS YP_002805424.1 226950333 7766772 complement(3328212..3329564) 1 NC_012563.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 3329564 7766772 CLM_3299 Clostridium botulinum A2 str. Kyoto sodium:alanine symporter family protein YP_002805424.1 3328212 R 536232 CDS YP_002805425.1 226950334 7766911 complement(3330514..3332805) 1 NC_012563.1 putative helicase 3332805 7766911 CLM_3300 Clostridium botulinum A2 str. Kyoto putative helicase YP_002805425.1 3330514 R 536232 CDS YP_002805426.1 226950335 7765745 complement(3333313..3334374) 1 NC_012563.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 3334374 mnmA 7765745 mnmA Clostridium botulinum A2 str. Kyoto tRNA-specific 2-thiouridylase MnmA YP_002805426.1 3333313 R 536232 CDS YP_002805427.1 226950336 7767721 complement(3334547..3335155) 1 NC_012563.1 identified by match to protein family HMM PF05257; chap domain-containing protein 3335155 7767721 CLM_3302 Clostridium botulinum A2 str. Kyoto chap domain-containing protein YP_002805427.1 3334547 R 536232 CDS YP_002805428.1 226950337 7766890 complement(3335561..3337192) 1 NC_012563.1 identified by match to protein family HMM PF01546; peptidase, M20/M25/M40 family 3337192 7766890 CLM_3303 Clostridium botulinum A2 str. Kyoto peptidase, M20/M25/M40 family YP_002805428.1 3335561 R 536232 CDS YP_002805429.1 226950338 7765931 complement(3337192..3337689) 1 NC_012563.1 hypothetical protein 3337689 7765931 CLM_3304 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805429.1 3337192 R 536232 CDS YP_002805430.1 226950339 7765117 3338023..3339348 1 NC_012563.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; transporter, HlyC/CorC family 3339348 7765117 CLM_3305 Clostridium botulinum A2 str. Kyoto transporter, HlyC/CorC family YP_002805430.1 3338023 D 536232 CDS YP_002805431.1 226950340 7767676 complement(3339701..3339991) 1 NC_012563.1 identified by match to protein family HMM PF01910; hypothetical protein 3339991 7767676 CLM_3306 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805431.1 3339701 R 536232 CDS YP_002805432.1 226950341 7766805 complement(3340010..3341323) 1 NC_012563.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 3341323 thiC 7766805 thiC Clostridium botulinum A2 str. Kyoto thiamine biosynthesis protein ThiC YP_002805432.1 3340010 R 536232 CDS YP_002805433.1 226950342 7765928 complement(3341534..3342910) 1 NC_012563.1 identified by match to protein family HMM PF00156; match to protein family HMM PF00310; match to protein family HMM TIGR01134; amidophosphoribosyltransferase 3342910 purF 7765928 purF Clostridium botulinum A2 str. Kyoto amidophosphoribosyltransferase YP_002805433.1 3341534 R 536232 CDS YP_002805434.1 226950343 7767577 complement(3343173..3343454) 1 NC_012563.1 identified by match to protein family HMM PF04456; hypothetical protein 3343454 7767577 CLM_3310 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805434.1 3343173 R 536232 CDS YP_002805435.1 226950344 7766632 complement(3343510..3344199) 1 NC_012563.1 hypothetical protein 3344199 7766632 CLM_3311 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805435.1 3343510 R 536232 CDS YP_002805436.1 226950345 7767627 complement(3344201..3344374) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 3344374 7767627 CLM_3312 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805436.1 3344201 R 536232 CDS YP_002805437.1 226950346 7766414 complement(3344479..3344850) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 3344850 7766414 CLM_3313 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805437.1 3344479 R 536232 CDS YP_002805438.1 226950347 7765334 complement(3344857..3345714) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3345714 7765334 CLM_3314 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002805438.1 3344857 R 536232 CDS YP_002805439.1 226950348 7764213 complement(3345921..3346292) 1 NC_012563.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 3346292 7764213 CLM_3315 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002805439.1 3345921 R 536232 CDS YP_002805440.1 226950349 7765113 3346930..3347442 1 NC_012563.1 hypothetical protein 3347442 7765113 CLM_3316 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805440.1 3346930 D 536232 CDS YP_002805441.1 226950350 7767799 complement(3347713..3348456) 1 NC_012563.1 identified by match to protein family HMM PF00037; iron-sulfur cluster-binding protein 3348456 7767799 CLM_3317 Clostridium botulinum A2 str. Kyoto iron-sulfur cluster-binding protein YP_002805441.1 3347713 R 536232 CDS YP_002805442.1 226950351 7766676 3348562..3349239 1 NC_012563.1 identified by match to protein family HMM PF00027; cyclic nucleotide-binding protein 3349239 7766676 CLM_3318 Clostridium botulinum A2 str. Kyoto cyclic nucleotide-binding protein YP_002805442.1 3348562 D 536232 CDS YP_002805443.1 226950352 7765661 3349328..3349771 1 NC_012563.1 identified by match to protein family HMM PF07486; putative cell wall hydrolase 3349771 7765661 CLM_3319 Clostridium botulinum A2 str. Kyoto putative cell wall hydrolase YP_002805443.1 3349328 D 536232 CDS YP_002805444.1 226950353 7766497 3349794..3350333 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3350333 7766497 CLM_3320 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805444.1 3349794 D 536232 CDS YP_002805445.1 226950354 7765608 complement(3350597..3350941) 1 NC_012563.1 identified by match to protein family HMM PF07883; hypothetical protein 3350941 7765608 CLM_3321 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805445.1 3350597 R 536232 CDS YP_002805446.1 226950355 7767688 complement(3351060..3353219) 1 NC_012563.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR03061; match to protein family HMM TIGR03062; putative phage infection protein 3353219 7767688 CLM_3322 Clostridium botulinum A2 str. Kyoto putative phage infection protein YP_002805446.1 3351060 R 536232 CDS YP_002805447.1 226950356 7766790 complement(3353528..3354280) 1 NC_012563.1 identified by match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase family protein 3354280 7766790 CLM_3323 Clostridium botulinum A2 str. Kyoto glycerophosphoryl diester phosphodiesterase family protein YP_002805447.1 3353528 R 536232 CDS YP_002805448.1 226950357 7767773 complement(3354660..3355622) 1 NC_012563.1 TPR domain-containing protein 3355622 7767773 CLM_3324 Clostridium botulinum A2 str. Kyoto TPR domain-containing protein YP_002805448.1 3354660 R 536232 CDS YP_002805449.1 226950358 7766859 3356099..3357352 1 NC_012563.1 identified by match to protein family HMM PF00282; decarboxylase family protein 3357352 7766859 CLM_3325 Clostridium botulinum A2 str. Kyoto decarboxylase family protein YP_002805449.1 3356099 D 536232 CDS YP_002805450.1 226950359 7765963 complement(3357443..3358762) 1 NC_012563.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; CBS/transporter-associated domain-containing protein 3358762 7765963 CLM_3326 Clostridium botulinum A2 str. Kyoto CBS/transporter-associated domain-containing protein YP_002805450.1 3357443 R 536232 CDS YP_002805451.1 226950360 7768151 complement(3359405..3360139) 1 NC_012563.1 identified by match to protein family HMM PF02591; hypothetical protein 3360139 7768151 CLM_3328 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805451.1 3359405 R 536232 CDS YP_002805452.1 226950361 7767224 complement(3360278..3361081) 1 NC_012563.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; hypothetical protein 3361081 7767224 CLM_3329 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805452.1 3360278 R 536232 CDS YP_002805453.1 226950362 7766482 complement(3361072..3361761) 1 NC_012563.1 identified by match to protein family HMM PF04816; hypothetical protein 3361761 7766482 CLM_3330 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805453.1 3361072 R 536232 CDS YP_002805454.1 226950363 7765369 complement(3361837..3362724) 1 NC_012563.1 hypothetical protein 3362724 7765369 CLM_3331 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805454.1 3361837 R 536232 CDS YP_002805455.1 226950364 7766542 complement(3362799..3363884) 1 NC_012563.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 3363884 rpoD 7766542 rpoD Clostridium botulinum A2 str. Kyoto RNA polymerase sigma factor RpoD YP_002805455.1 3362799 R 536232 CDS YP_002805456.1 226950365 7767228 complement(3363909..3365681) 1 NC_012563.1 synthesizes RNA primers at the replication forks; DNA primase 3365681 dnaG 7767228 dnaG Clostridium botulinum A2 str. Kyoto DNA primase YP_002805456.1 3363909 R 536232 CDS YP_002805457.1 226950366 7765055 complement(3365964..3366992) 1 NC_012563.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 3366992 7765055 CLM_3334 Clostridium botulinum A2 str. Kyoto deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_002805457.1 3365964 R 536232 CDS YP_002805458.1 226950367 7765483 3367134..3368204 1 NC_012563.1 identified by match to protein family HMM TIGR02906; spore coat protein-like protein 3368204 7765483 CLM_3335 Clostridium botulinum A2 str. Kyoto spore coat protein-like protein YP_002805458.1 3367134 D 536232 CDS YP_002805459.1 226950368 7767019 complement(3368257..3370890) 1 NC_012563.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 3370890 ppdK 7767019 ppdK Clostridium botulinum A2 str. Kyoto pyruvate phosphate dikinase YP_002805459.1 3368257 R 536232 CDS YP_002805460.1 226950369 7765798 complement(3370970..3371611) 1 NC_012563.1 identified by match to protein family HMM PF00571; match to protein family HMM PF08279; CBS domain-containing protein 3371611 7765798 CLM_3337 Clostridium botulinum A2 str. Kyoto CBS domain-containing protein YP_002805460.1 3370970 R 536232 CDS YP_002805461.1 226950370 7767018 complement(3372128..3372748) 1 NC_012563.1 identified by match to protein family HMM PF00627; UBA/TS-N domain-containing protein 3372748 7767018 CLM_3338 Clostridium botulinum A2 str. Kyoto UBA/TS-N domain-containing protein YP_002805461.1 3372128 R 536232 CDS YP_002805462.1 226950371 7764785 complement(3373516..3374406) 1 NC_012563.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 3374406 era 7764785 era Clostridium botulinum A2 str. Kyoto GTP-binding protein Era YP_002805462.1 3373516 R 536232 CDS YP_002805463.1 226950372 7766278 complement(3374422..3374820) 1 NC_012563.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 3374820 cdd 7766278 cdd Clostridium botulinum A2 str. Kyoto cytidine deaminase YP_002805463.1 3374422 R 536232 CDS YP_002805464.1 226950373 7767111 complement(3374904..3375602) 1 NC_012563.1 identified by match to protein family HMM PF01219; match to protein family HMM PF01569; diacylglycerol kinase/PAP2 family protein 3375602 7767111 CLM_3342 Clostridium botulinum A2 str. Kyoto diacylglycerol kinase/PAP2 family protein YP_002805464.1 3374904 R 536232 CDS YP_002805465.1 226950374 7764616 complement(3375643..3376143) 1 NC_012563.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; putative metalloprotease 3376143 7764616 CLM_3343 Clostridium botulinum A2 str. Kyoto putative metalloprotease YP_002805465.1 3375643 R 536232 CDS YP_002805466.1 226950375 7765435 complement(3376140..3378227) 1 NC_012563.1 identified by match to protein family HMM PF01966; match to protein family HMM PF07697; match to protein family HMM PF07698; match to protein family HMM TIGR00277; putative hydrolase 3378227 7765435 CLM_3344 Clostridium botulinum A2 str. Kyoto putative hydrolase YP_002805466.1 3376140 R 536232 CDS YP_002805467.1 226950376 7766562 complement(3378250..3379410) 1 NC_012563.1 identified by match to protein family HMM PF06898; match to protein family HMM TIGR02876; sporulation protein YqfD 3379410 7766562 CLM_3345 Clostridium botulinum A2 str. Kyoto sporulation protein YqfD YP_002805467.1 3378250 R 536232 CDS YP_002805468.1 226950377 7765726 complement(3379400..3379696) 1 NC_012563.1 identified by match to protein family HMM PF07241; match to protein family HMM TIGR02856; sporulation protein YqfC 3379696 yqfC 7765726 yqfC Clostridium botulinum A2 str. Kyoto sporulation protein YqfC YP_002805468.1 3379400 R 536232 CDS YP_002805469.1 226950378 7764311 complement(3379810..3380256) 1 NC_012563.1 identified by match to protein family HMM PF09424; GatB/Yqey domain-containing protein 3380256 7764311 CLM_3347 Clostridium botulinum A2 str. Kyoto GatB/Yqey domain-containing protein YP_002805469.1 3379810 R 536232 CDS YP_002805470.1 226950379 7764901 complement(3380299..3380475) 1 NC_012563.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3380475 rpsU 7764901 rpsU Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S21 YP_002805470.1 3380299 R 536232 CDS YP_002805471.1 226950380 7764832 complement(3380612..3380956) 1 NC_012563.1 identified by match to protein family HMM PF01230; HIT family protein 3380956 7764832 CLM_3349 Clostridium botulinum A2 str. Kyoto HIT family protein YP_002805471.1 3380612 R 536232 CDS YP_002805472.1 226950381 7767910 complement(3381013..3382311) 1 NC_012563.1 identified by match to protein family HMM PF00919; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01579; RNA modification enzyme, MiaB family 3382311 7767910 CLM_3350 Clostridium botulinum A2 str. Kyoto RNA modification enzyme, MiaB family YP_002805472.1 3381013 R 536232 CDS YP_002805473.1 226950382 7767069 complement(3382311..3383069) 1 NC_012563.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3383069 7767069 CLM_3351 Clostridium botulinum A2 str. Kyoto 16S ribosomal RNA methyltransferase RsmE YP_002805473.1 3382311 R 536232 CDS YP_002805474.1 226950383 7766173 complement(3383167..3384105) 1 NC_012563.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 3384105 prmA 7766173 prmA Clostridium botulinum A2 str. Kyoto ribosomal protein L11 methyltransferase YP_002805474.1 3383167 R 536232 CDS YP_002805475.1 226950384 7764230 complement(3384281..3385426) 1 NC_012563.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 3385426 dnaJ 7764230 dnaJ Clostridium botulinum A2 str. Kyoto chaperone protein DnaJ YP_002805475.1 3384281 R 536232 CDS YP_002805476.1 226950385 7765313 complement(3385569..3387440) 1 NC_012563.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 3387440 dnaK 7765313 dnaK Clostridium botulinum A2 str. Kyoto molecular chaperone DnaK YP_002805476.1 3385569 R 536232 CDS YP_002805477.1 226950386 7766493 complement(3387495..3388139) 1 NC_012563.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 3388139 grpE 7766493 grpE Clostridium botulinum A2 str. Kyoto heat shock protein GrpE YP_002805477.1 3387495 R 536232 CDS YP_002805478.1 226950387 7767601 complement(3388166..3389197) 1 NC_012563.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 3389197 hrcA 7767601 hrcA Clostridium botulinum A2 str. Kyoto heat-inducible transcription repressor YP_002805478.1 3388166 R 536232 CDS YP_002805479.1 226950388 7766525 complement(3389398..3390540) 1 NC_012563.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3390540 7766525 CLM_3357 Clostridium botulinum A2 str. Kyoto coproporphyrinogen III oxidase YP_002805479.1 3389398 R 536232 CDS YP_002805480.1 226950389 7765674 complement(3390567..3392375) 1 NC_012563.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 3392375 lepA 7765674 lepA Clostridium botulinum A2 str. Kyoto GTP-binding protein LepA YP_002805480.1 3390567 R 536232 CDS YP_002805481.1 226950390 7764804 complement(3392516..3392911) 1 NC_012563.1 hypothetical protein 3392911 7764804 CLM_3359 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805481.1 3392516 R 536232 CDS YP_002805482.1 226950391 7767926 complement(3392982..3394073) 1 NC_012563.1 identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867; stage II sporulation protein 3394073 7767926 CLM_3360 Clostridium botulinum A2 str. Kyoto stage II sporulation protein YP_002805482.1 3392982 R 536232 CDS YP_002805483.1 226950392 7766282 complement(3394258..3395232) 1 NC_012563.1 Initiates the rapid degradation of small, acid-soluble proteins during spore germination; germination protease 3395232 gpr 7766282 gpr Clostridium botulinum A2 str. Kyoto germination protease YP_002805483.1 3394258 R 536232 CDS YP_002805484.1 226950393 7765170 3395442..3395708 1 NC_012563.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 3395708 rpsT 7765170 rpsT Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S20 YP_002805484.1 3395442 D 536232 CDS YP_002805485.1 226950394 7764962 complement(3395743..3396774) 1 NC_012563.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 3396774 holA 7764962 holA Clostridium botulinum A2 str. Kyoto DNA polymerase III subunit delta YP_002805485.1 3395743 R 536232 CDS YP_002805486.1 226950395 7768083 complement(3396803..3398590) 1 NC_012563.1 identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; ComEC/Rec2 family protein 3398590 7768083 CLM_3364 Clostridium botulinum A2 str. Kyoto ComEC/Rec2 family protein YP_002805486.1 3396803 R 536232 CDS YP_002805487.1 226950396 7766546 complement(3398602..3398832) 1 NC_012563.1 hypothetical protein 3398832 7766546 CLM_3365 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805487.1 3398602 R 536232 CDS YP_002805488.1 226950397 7765711 complement(3398937..3401531) 1 NC_012563.1 identified by match to protein family HMM PF00122; putative cation transporting ATPase 3401531 7765711 CLM_3366 Clostridium botulinum A2 str. Kyoto putative cation transporting ATPase YP_002805488.1 3398937 R 536232 CDS YP_002805489.1 226950398 7765425 complement(3402039..3403553) 1 NC_012563.1 identified by match to protein family HMM PF07556; hypothetical protein 3403553 7765425 CLM_3367 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805489.1 3402039 R 536232 CDS YP_002805490.1 226950399 7768212 complement(3405062..3406969) 1 NC_012563.1 identified by match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00231; match to protein family HMM TIGR00475; selenocysteine-specific translation elongation factor 3406969 selB 7768212 selB Clostridium botulinum A2 str. Kyoto selenocysteine-specific translation elongation factor YP_002805490.1 3405062 R 536232 CDS YP_002805491.1 226950400 7766295 complement(3406988..3408376) 1 NC_012563.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 3408376 selA 7766295 selA Clostridium botulinum A2 str. Kyoto selenocysteine synthase YP_002805491.1 3406988 R 536232 CDS YP_002805492.1 226950401 7764390 complement(3408443..3409408) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00476; selenide, water dikinase 3409408 selD 7764390 selD Clostridium botulinum A2 str. Kyoto selenide, water dikinase YP_002805492.1 3408443 R 536232 CDS YP_002805493.1 226950402 7767469 complement(3409628..3410236) 1 NC_012563.1 identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426; putative comE operon protein 1 3410236 7767469 CLM_3373 Clostridium botulinum A2 str. Kyoto putative comE operon protein 1 YP_002805493.1 3409628 R 536232 CDS YP_002805494.1 226950403 7768106 3410425..3411672 1 NC_012563.1 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase family protein 3411672 7768106 CLM_3374 Clostridium botulinum A2 str. Kyoto D-alanyl-D-alanine carboxypeptidase family protein YP_002805494.1 3410425 D 536232 CDS YP_002805495.1 226950404 7765236 complement(3411780..3412682) 1 NC_012563.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005; RluA family pseudouridine synthase 3412682 7765236 CLM_3375 Clostridium botulinum A2 str. Kyoto RluA family pseudouridine synthase YP_002805495.1 3411780 R 536232 CDS YP_002805496.1 226950405 7766082 complement(3413008..3413388) 1 NC_012563.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; putative endoribonuclease L-PSP 3413388 7766082 CLM_3376 Clostridium botulinum A2 str. Kyoto putative endoribonuclease L-PSP YP_002805496.1 3413008 R 536232 CDS YP_002805497.1 226950406 7764918 complement(3413404..3414678) 1 NC_012563.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; putative cell envelope-related transcriptional attenuator 3414678 7764918 CLM_3377 Clostridium botulinum A2 str. Kyoto putative cell envelope-related transcriptional attenuator YP_002805497.1 3413404 R 536232 CDS YP_002805498.1 226950407 7765442 complement(3414689..3415258) 1 NC_012563.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR00488; HDIG domain-containing protein 3415258 7765442 CLM_3378 Clostridium botulinum A2 str. Kyoto HDIG domain-containing protein YP_002805498.1 3414689 R 536232 CDS YP_002805499.1 226950408 7764303 complement(3415341..3415946) 1 NC_012563.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 3415946 nadD 7764303 nadD Clostridium botulinum A2 str. Kyoto nicotinic acid mononucleotide adenylyltransferase YP_002805499.1 3415341 R 536232 CDS YP_002805500.1 226950409 7767666 complement(3416189..3416482) 1 NC_012563.1 identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253; putative RNA-binding protein 3416482 7767666 CLM_3380 Clostridium botulinum A2 str. Kyoto putative RNA-binding protein YP_002805500.1 3416189 R 536232 CDS YP_002805501.1 226950410 7766515 complement(3416509..3417783) 1 NC_012563.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3417783 obgE 7766515 obgE Clostridium botulinum A2 str. Kyoto GTPase ObgE YP_002805501.1 3416509 R 536232 CDS YP_002805502.1 226950411 7764828 complement(3418162..3418464) 1 NC_012563.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 3418464 rpmA 7764828 rpmA Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L27 YP_002805502.1 3418162 R 536232 CDS YP_002805503.1 226950412 7765987 complement(3418467..3418793) 1 NC_012563.1 identified by match to protein family HMM PF04327; hypothetical protein 3418793 7765987 CLM_3383 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805503.1 3418467 R 536232 CDS YP_002805504.1 226950413 7765672 complement(3418796..3419110) 1 NC_012563.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 3419110 rplU 7765672 rplU Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L21 YP_002805504.1 3418796 R 536232 CDS YP_002805505.1 226950414 7765539 complement(3419234..3420673) 1 NC_012563.1 identified by match to protein family HMM PF00575; match to protein family HMM TIGR00757; ribonuclease, Rne/Rng family 3420673 7765539 CLM_3386 Clostridium botulinum A2 str. Kyoto ribonuclease, Rne/Rng family YP_002805505.1 3419234 R 536232 CDS YP_002805506.1 226950415 7766389 complement(3420712..3421425) 1 NC_012563.1 hypothetical protein 3421425 7766389 CLM_3387 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805506.1 3420712 R 536232 CDS YP_002805507.1 226950416 7767270 complement(3421403..3423253) 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 3423253 7767270 CLM_3388 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002805507.1 3421403 R 536232 CDS YP_002805508.1 226950417 7765251 complement(3423366..3424217) 1 NC_012563.1 identified by match to protein family HMM PF02163; putative metalloprotease 3424217 7765251 CLM_3389 Clostridium botulinum A2 str. Kyoto putative metalloprotease YP_002805508.1 3423366 R 536232 CDS YP_002805509.1 226950418 7767156 complement(3424272..3425057) 1 NC_012563.1 identified by match to protein family HMM PF01551; peptidase, family M23/M37 3425057 7767156 CLM_3390 Clostridium botulinum A2 str. Kyoto peptidase, family M23/M37 YP_002805509.1 3424272 R 536232 CDS YP_002805510.1 226950419 7767992 complement(3425377..3426495) 1 NC_012563.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210; rod shape-determining protein RodA 3426495 rodA 7767992 rodA Clostridium botulinum A2 str. Kyoto rod shape-determining protein RodA YP_002805510.1 3425377 R 536232 CDS YP_002805511.1 226950420 7764790 complement(3426594..3426857) 1 NC_012563.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 3426857 minE 7764790 minE Clostridium botulinum A2 str. Kyoto cell division topological specificity factor MinE YP_002805511.1 3426594 R 536232 CDS YP_002805512.1 226950421 7767738 complement(3426871..3427668) 1 NC_012563.1 identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968; septum site-determining protein MinD 3427668 minD 7767738 minD Clostridium botulinum A2 str. Kyoto septum site-determining protein MinD YP_002805512.1 3426871 R 536232 CDS YP_002805513.1 226950422 7764494 complement(3427686..3428315) 1 NC_012563.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 3428315 minC 7764494 minC Clostridium botulinum A2 str. Kyoto septum formation inhibitor YP_002805513.1 3427686 R 536232 CDS YP_002805514.1 226950423 7764758 complement(3428490..3431264) 1 NC_012563.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin-binding protein 3431264 7764758 CLM_3395 Clostridium botulinum A2 str. Kyoto penicillin-binding protein YP_002805514.1 3428490 R 536232 CDS YP_002805515.1 226950424 7765891 complement(3431284..3431775) 1 NC_012563.1 identified by match to protein family HMM PF04093; match to protein family HMM TIGR03426; rod shape-determining protein MreD 3431775 mreD 7765891 mreD Clostridium botulinum A2 str. Kyoto rod shape-determining protein MreD YP_002805515.1 3431284 R 536232 CDS YP_002805516.1 226950425 7767032 complement(3431786..3432643) 1 NC_012563.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 3432643 mreC 7767032 mreC Clostridium botulinum A2 str. Kyoto rod shape-determining protein MreC YP_002805516.1 3431786 R 536232 CDS YP_002805517.1 226950426 7768039 complement(3432650..3433660) 1 NC_012563.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 3433660 7768039 CLM_3398 Clostridium botulinum A2 str. Kyoto rod shape-determining protein MreB YP_002805517.1 3432650 R 536232 CDS YP_002805518.1 226950427 7767015 complement(3433689..3434375) 1 NC_012563.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 3434375 radC 7767015 radC Clostridium botulinum A2 str. Kyoto DNA repair protein RadC YP_002805518.1 3433689 R 536232 CDS YP_002805519.1 226950428 7766156 complement(3434390..3434974) 1 NC_012563.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3434974 maf 7766156 maf Clostridium botulinum A2 str. Kyoto Maf-like protein YP_002805519.1 3434390 R 536232 CDS YP_002805520.1 226950429 7767325 complement(3434990..3435247) 1 NC_012563.1 hypothetical protein 3435247 7767325 CLM_3401 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805520.1 3434990 R 536232 CDS YP_002805521.1 226950430 7764500 complement(3435357..3436058) 1 NC_012563.1 hypothetical protein 3436058 7764500 CLM_3402 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805521.1 3435357 R 536232 CDS YP_002805522.1 226950431 7766148 complement(3436284..3436823) 1 NC_012563.1 hypothetical protein 3436823 7766148 CLM_3403 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805522.1 3436284 R 536232 CDS YP_002805523.1 226950432 7764981 3437206..3437760 1 NC_012563.1 identified by match to protein family HMM PF02567; hypothetical protein 3437760 7764981 CLM_3404 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805523.1 3437206 D 536232 CDS YP_002805524.1 226950433 7765700 complement(3437819..3438256) 1 NC_012563.1 hypothetical protein 3438256 pheB 7765700 pheB Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805524.1 3437819 R 536232 CDS YP_002805525.1 226950434 7764846 complement(3438313..3438447) 1 NC_012563.1 hypothetical protein 3438447 7764846 CLM_3406 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805525.1 3438313 R 536232 CDS YP_002805526.1 226950435 7768227 complement(3438991..3439536) 1 NC_012563.1 identified by match to protein family HMM PF01464; transglycosylase SLT domain-containing protein 3439536 7768227 CLM_3409 Clostridium botulinum A2 str. Kyoto transglycosylase SLT domain-containing protein YP_002805526.1 3438991 R 536232 CDS YP_002805527.1 226950436 7766569 complement(3439554..3440192) 1 NC_012563.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 3440192 coaE 7766569 coaE Clostridium botulinum A2 str. Kyoto dephospho-CoA kinase YP_002805527.1 3439554 R 536232 CDS YP_002805528.1 226950437 7765249 complement(3440204..3442831) 1 NC_012563.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 3442831 polA 7765249 polA Clostridium botulinum A2 str. Kyoto DNA polymerase I YP_002805528.1 3440204 R 536232 CDS YP_002805529.1 226950438 7767987 complement(3442849..3443973) 1 NC_012563.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 3443973 aroC 7767987 aroC Clostridium botulinum A2 str. Kyoto chorismate synthase YP_002805529.1 3442849 R 536232 CDS YP_002805530.1 226950439 7766681 complement(3444372..3445151) 1 NC_012563.1 identified by match to protein family HMM PF01520; match to protein family HMM PF08239; N-acetylmuramoyl-L-alanine amidase 3445151 7766681 CLM_3413 Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase YP_002805530.1 3444372 R 536232 CDS YP_002805531.1 226950440 7765753 complement(3445298..3445492) 1 NC_012563.1 hypothetical protein 3445492 7765753 CLM_3414 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805531.1 3445298 R 536232 CDS YP_002805532.1 226950441 7764867 complement(3445511..3445765) 1 NC_012563.1 hypothetical protein 3445765 7764867 CLM_3415 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805532.1 3445511 R 536232 CDS YP_002805533.1 226950442 7766529 complement(3445917..3446726) 1 NC_012563.1 cell adhesion domain-containing protein 3446726 7766529 CLM_3416 Clostridium botulinum A2 str. Kyoto cell adhesion domain-containing protein YP_002805533.1 3445917 R 536232 CDS YP_002805534.1 226950443 7767132 complement(3446778..3448121) 1 NC_012563.1 cell adhesion domain-containing protein 3448121 7767132 CLM_3417 Clostridium botulinum A2 str. Kyoto cell adhesion domain-containing protein YP_002805534.1 3446778 R 536232 CDS YP_002805535.1 226950444 7764203 complement(3449057..3449764) 1 NC_012563.1 identified by similarity to GB:ABS41377.1; cell adhesion domain-containing protein 3449764 7764203 CLM_3419 Clostridium botulinum A2 str. Kyoto cell adhesion domain-containing protein YP_002805535.1 3449057 R 536232 CDS YP_002805536.1 226950445 7765291 complement(3450034..3450840) 1 NC_012563.1 identified by similarity to GB:AAO35690.1; hypothetical protein 3450840 7765291 CLM_3420 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805536.1 3450034 R 536232 CDS YP_002805537.1 226950446 7764276 complement(3450894..3451682) 1 NC_012563.1 identified by similarity to GB:AAO35690.1; hypothetical protein 3451682 7764276 CLM_3421 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805537.1 3450894 R 536232 CDS YP_002805538.1 226950447 7765371 complement(3451696..3452703) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02210; cell adhesion domain-containing protein 3452703 7765371 CLM_3422 Clostridium botulinum A2 str. Kyoto cell adhesion domain-containing protein YP_002805538.1 3451696 R 536232 CDS YP_002805539.1 226950448 7765883 complement(3452706..3453488) 1 NC_012563.1 hypothetical protein 3453488 7765883 CLM_3423 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805539.1 3452706 R 536232 CDS YP_002805540.1 226950449 7767516 complement(3453579..3454664) 1 NC_012563.1 hypothetical protein 3454664 7767516 CLM_3424 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805540.1 3453579 R 536232 CDS YP_002805541.1 226950450 7766368 complement(3454676..3455674) 1 NC_012563.1 hypothetical protein 3455674 7766368 CLM_3425 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805541.1 3454676 R 536232 CDS YP_002805542.1 226950451 7768014 complement(3455686..3455940) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3455940 7768014 CLM_3426 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805542.1 3455686 R 536232 CDS YP_002805543.1 226950452 7765439 complement(3455946..3457841) 1 NC_012563.1 hypothetical protein 3457841 7765439 CLM_3427 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805543.1 3455946 R 536232 CDS YP_002805544.1 226950453 7766629 complement(3457856..3459091) 1 NC_012563.1 hypothetical protein 3459091 7766629 CLM_3428 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805544.1 3457856 R 536232 CDS YP_002805545.1 226950454 7764743 complement(3459114..3460091) 1 NC_012563.1 hypothetical protein 3460091 7764743 CLM_3429 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805545.1 3459114 R 536232 CDS YP_002805546.1 226950455 7764511 complement(3460093..3461442) 1 NC_012563.1 identified by match to protein family HMM PF00656; hypothetical protein 3461442 7764511 CLM_3430 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805546.1 3460093 R 536232 CDS YP_002805547.1 226950456 7766070 complement(3461457..3461798) 1 NC_012563.1 hypothetical protein 3461798 7766070 CLM_3431 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805547.1 3461457 R 536232 CDS YP_002805548.1 226950457 7766710 complement(3461811..3462896) 1 NC_012563.1 hypothetical protein 3462896 7766710 CLM_3432 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805548.1 3461811 R 536232 CDS YP_002805549.1 226950458 7767393 complement(3462883..3463317) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3463317 7767393 CLM_3433 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805549.1 3462883 R 536232 CDS YP_002805550.1 226950459 7764929 complement(3463330..3464871) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3464871 7764929 CLM_3434 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805550.1 3463330 R 536232 CDS YP_002805551.1 226950460 7766786 complement(3465056..3465223) 1 NC_012563.1 hypothetical protein 3465223 7766786 CLM_3435 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805551.1 3465056 R 536232 CDS YP_002805552.1 226950461 7765914 complement(3465258..3465674) 1 NC_012563.1 hypothetical protein 3465674 7765914 CLM_3436 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805552.1 3465258 R 536232 CDS YP_002805553.1 226950462 7765958 complement(3465689..3466576) 1 NC_012563.1 hypothetical protein 3466576 7765958 CLM_3437 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805553.1 3465689 R 536232 CDS YP_002805554.1 226950463 7765081 complement(3466581..3467000) 1 NC_012563.1 hypothetical protein 3467000 7765081 CLM_3438 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805554.1 3466581 R 536232 CDS YP_002805555.1 226950464 7766394 complement(3467006..3467353) 1 NC_012563.1 hypothetical protein 3467353 7766394 CLM_3439 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805555.1 3467006 R 536232 CDS YP_002805556.1 226950465 7765543 complement(3467358..3467723) 1 NC_012563.1 hypothetical protein 3467723 7765543 CLM_3440 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805556.1 3467358 R 536232 CDS YP_002805557.1 226950466 7767626 complement(3467723..3468007) 1 NC_012563.1 hypothetical protein 3468007 7767626 CLM_3441 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805557.1 3467723 R 536232 CDS YP_002805558.1 226950467 7766730 complement(3468674..3469195) 1 NC_012563.1 hypothetical protein 3469195 7766730 CLM_3442 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805558.1 3468674 R 536232 CDS YP_002805559.1 226950468 7765867 complement(3469308..3469628) 1 NC_012563.1 hypothetical protein 3469628 7765867 CLM_3443 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805559.1 3469308 R 536232 CDS YP_002805560.1 226950469 7765069 complement(3469685..3470485) 1 NC_012563.1 hypothetical protein 3470485 7765069 CLM_3444 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805560.1 3469685 R 536232 CDS YP_002805561.1 226950470 7765070 complement(3470475..3471380) 1 NC_012563.1 identified by match to protein family HMM PF09681; match to protein family HMM TIGR01714; putative phage replisome organizer 3471380 7765070 CLM_3445 Clostridium botulinum A2 str. Kyoto putative phage replisome organizer YP_002805561.1 3470475 R 536232 CDS YP_002805562.1 226950471 7767753 complement(3471474..3471686) 1 NC_012563.1 identified by match to protein family HMM PF01381; putative DNA-binding protein 3471686 7767753 CLM_3446 Clostridium botulinum A2 str. Kyoto putative DNA-binding protein YP_002805562.1 3471474 R 536232 CDS YP_002805563.1 226950472 7765681 complement(3471748..3471957) 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 3471957 7765681 CLM_3447 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002805563.1 3471748 R 536232 CDS YP_002805564.1 226950473 7765411 3472149..3472559 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 3472559 7765411 CLM_3448 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002805564.1 3472149 D 536232 CDS YP_002805565.1 226950474 7764614 3472861..3473010 1 NC_012563.1 hypothetical protein 3473010 7764614 CLM_3449 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805565.1 3472861 D 536232 CDS YP_002805566.1 226950475 7768225 3474078..3475565 1 NC_012563.1 identified by similarity to SP:Q51392; match to protein family HMM PF03062; alginate O-acetyltransferase AlgI 3475565 7768225 CLM_3451 Clostridium botulinum A2 str. Kyoto alginate O-acetyltransferase AlgI YP_002805566.1 3474078 D 536232 CDS YP_002805567.1 226950476 7765222 3475578..3477029 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3477029 7765222 CLM_3452 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805567.1 3475578 D 536232 CDS YP_002805568.1 226950477 7764383 complement(3477196..3477399) 1 NC_012563.1 identified by match to protein family HMM PF00269; small, acid-soluble spore protein 3477399 7764383 CLM_3453 Clostridium botulinum A2 str. Kyoto small, acid-soluble spore protein YP_002805568.1 3477196 R 536232 CDS YP_002805569.1 226950478 7768084 complement(3477563..3477703) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3477703 7768084 CLM_3454 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805569.1 3477563 R 536232 CDS YP_002805570.1 226950479 7766714 complement(3477943..3478062) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3478062 7766714 CLM_3455 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805570.1 3477943 R 536232 CDS YP_002805571.1 226950480 7766349 complement(3478119..3478409) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3478409 7766349 CLM_3456 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805571.1 3478119 R 536232 CDS YP_002805572.1 226950481 7765446 complement(3478550..3478678) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3478678 7765446 CLM_3457 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805572.1 3478550 R 536232 CDS YP_002805573.1 226950482 7764651 3478851..3479279 1 NC_012563.1 identified by match to protein family HMM PF04246; sigma-E factor regulator, RseC/MucC family 3479279 7764651 CLM_3458 Clostridium botulinum A2 str. Kyoto sigma-E factor regulator, RseC/MucC family YP_002805573.1 3478851 D 536232 CDS YP_002805574.1 226950483 7765434 complement(3479314..3481095) 1 NC_012563.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 3481095 aspS 7765434 aspS Clostridium botulinum A2 str. Kyoto aspartyl-tRNA synthetase YP_002805574.1 3479314 R 536232 CDS YP_002805575.1 226950484 7764587 complement(3481135..3482382) 1 NC_012563.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 3482382 hisS 7764587 hisS Clostridium botulinum A2 str. Kyoto histidyl-tRNA synthetase YP_002805575.1 3481135 R 536232 CDS YP_002805576.1 226950485 7766678 complement(3482401..3483831) 1 NC_012563.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3483831 7766678 CLM_3461 Clostridium botulinum A2 str. Kyoto coproporphyrinogen III oxidase YP_002805576.1 3482401 R 536232 CDS YP_002805577.1 226950486 7765779 complement(3483869..3484468) 1 NC_012563.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 3484468 7765779 CLM_3462 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002805577.1 3483869 R 536232 CDS YP_002805578.1 226950487 7764959 complement(3484529..3484978) 1 NC_012563.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 3484978 dtd 7764959 dtd Clostridium botulinum A2 str. Kyoto D-tyrosyl-tRNA(Tyr) deacylase YP_002805578.1 3484529 R 536232 CDS YP_002805579.1 226950488 7768061 complement(3485021..3487192) 1 NC_012563.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; GTP pyrophosphokinase 3487192 relA 7768061 relA Clostridium botulinum A2 str. Kyoto GTP pyrophosphokinase YP_002805579.1 3485021 R 536232 CDS YP_002805580.1 226950489 7766219 complement(3487317..3487835) 1 NC_012563.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 3487835 apt 7766219 apt Clostridium botulinum A2 str. Kyoto adenine phosphoribosyltransferase YP_002805580.1 3487317 R 536232 CDS YP_002805581.1 226950490 7765139 complement(3487944..3488822) 1 NC_012563.1 identified by match to protein family HMM PF01368; DHH domain-containing protein 3488822 7765139 CLM_3466 Clostridium botulinum A2 str. Kyoto DHH domain-containing protein YP_002805581.1 3487944 R 536232 CDS YP_002805582.1 226950491 7766174 complement(3489051..3489914) 1 NC_012563.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 3489914 secF 7766174 secF Clostridium botulinum A2 str. Kyoto preprotein translocase subunit SecF YP_002805582.1 3489051 R 536232 CDS YP_002805583.1 226950492 7765293 complement(3489916..3491184) 1 NC_012563.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 3491184 secD 7765293 secD Clostridium botulinum A2 str. Kyoto preprotein translocase subunit SecD YP_002805583.1 3489916 R 536232 CDS YP_002805584.1 226950493 7767761 complement(3491278..3492645) 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 3492645 7767761 CLM_3469 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002805584.1 3491278 R 536232 CDS YP_002805585.1 226950494 7766868 complement(3492802..3492939) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3492939 7766868 CLM_3470 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805585.1 3492802 R 536232 CDS YP_002805586.1 226950495 7765990 complement(3493029..3493397) 1 NC_012563.1 hypothetical protein 3493397 7765990 CLM_3471 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805586.1 3493029 R 536232 CDS YP_002805587.1 226950496 7765071 complement(3493452..3493787) 1 NC_012563.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 3493787 yajC 7765071 yajC Clostridium botulinum A2 str. Kyoto preprotein translocase subunit YajC YP_002805587.1 3493452 R 536232 CDS YP_002805588.1 226950497 7767295 complement(3493967..3495097) 1 NC_012563.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 3495097 tgt 7767295 tgt Clostridium botulinum A2 str. Kyoto queuine tRNA-ribosyltransferase YP_002805588.1 3493967 R 536232 CDS YP_002805589.1 226950498 7767933 complement(3495153..3496178) 1 NC_012563.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 3496178 queA 7767933 queA Clostridium botulinum A2 str. Kyoto S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_002805589.1 3495153 R 536232 CDS YP_002805590.1 226950499 7765528 complement(3496212..3497240) 1 NC_012563.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 3497240 ruvB 7765528 ruvB Clostridium botulinum A2 str. Kyoto Holliday junction DNA helicase RuvB YP_002805590.1 3496212 R 536232 CDS YP_002805591.1 226950500 7764607 complement(3497260..3497853) 1 NC_012563.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 3497853 ruvA 7764607 ruvA Clostridium botulinum A2 str. Kyoto Holliday junction DNA helicase RuvA YP_002805591.1 3497260 R 536232 CDS YP_002805592.1 226950501 7765295 complement(3498035..3498646) 1 NC_012563.1 hypothetical protein 3498646 7765295 CLM_3477 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805592.1 3498035 R 536232 CDS YP_002805593.1 226950502 7767000 complement(3499024..3499764) 1 NC_012563.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 3499764 7767000 CLM_3478 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805593.1 3499024 R 536232 CDS YP_002805594.1 226950503 7768053 complement(3499915..3500565) 1 NC_012563.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257; hypothetical protein 3500565 7768053 CLM_3479 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805594.1 3499915 R 536232 CDS YP_002805595.1 226950504 7764855 complement(3500581..3501243) 1 NC_012563.1 identified by match to protein family HMM PF03130; PBS lyase HEAT-like repeat-containing protein 3501243 7764855 CLM_3480 Clostridium botulinum A2 str. Kyoto PBS lyase HEAT-like repeat-containing protein YP_002805595.1 3500581 R 536232 CDS YP_002805596.1 226950505 7765829 complement(3501331..3502749) 1 NC_012563.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 3502749 7765829 CLM_3481 Clostridium botulinum A2 str. Kyoto GntR family transcriptional regulator YP_002805596.1 3501331 R 536232 CDS YP_002805597.1 226950506 7765624 complement(3503034..3503927) 1 NC_012563.1 identified by match to protein family HMM PF01909; nucleotidyltransferase domain-containing protein 3503927 7765624 CLM_3482 Clostridium botulinum A2 str. Kyoto nucleotidyltransferase domain-containing protein YP_002805597.1 3503034 R 536232 CDS YP_002805598.1 226950507 7766272 complement(3504077..3504298) 1 NC_012563.1 hypothetical protein 3504298 7766272 CLM_3483 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805598.1 3504077 R 536232 CDS YP_002805599.1 226950508 7767362 complement(3504471..3504629) 1 NC_012563.1 identified by match to protein family HMM PF00301; rubredoxin 3504629 7767362 CLM_3484 Clostridium botulinum A2 str. Kyoto rubredoxin YP_002805599.1 3504471 R 536232 CDS YP_002805600.1 226950509 7765158 complement(3504758..3506542) 1 NC_012563.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231; match to protein family HMM TIGR03156; GTP-binding protein 3506542 7765158 CLM_3485 Clostridium botulinum A2 str. Kyoto GTP-binding protein YP_002805600.1 3504758 R 536232 CDS YP_002805601.1 226950510 7764332 3506684..3507208 1 NC_012563.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 3507208 hpt 7764332 hpt Clostridium botulinum A2 str. Kyoto hypoxanthine phosphoribosyltransferase YP_002805601.1 3506684 D 536232 CDS YP_002805602.1 226950511 7765277 complement(3507245..3507799) 1 NC_012563.1 identified by match to protein family HMM PF09560; match to protein family HMM TIGR02832; sporulation protein YunB 3507799 7765277 CLM_3487 Clostridium botulinum A2 str. Kyoto sporulation protein YunB YP_002805602.1 3507245 R 536232 CDS YP_002805603.1 226950512 7766628 3508071..3510566 1 NC_012563.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein, 1A family 3510566 7766628 CLM_3488 Clostridium botulinum A2 str. Kyoto penicillin-binding protein, 1A family YP_002805603.1 3508071 D 536232 CDS YP_002805604.1 226950513 7767423 complement(3510596..3510952) 1 NC_012563.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02839; stage V sporulation protein AE 3510952 spoVAE 7767423 spoVAE Clostridium botulinum A2 str. Kyoto stage V sporulation protein AE YP_002805604.1 3510596 R 536232 CDS YP_002805605.1 226950514 7764890 complement(3510968..3511975) 1 NC_012563.1 identified by match to protein family HMM PF07451; match to protein family HMM TIGR02845; stage V sporulation protein AD 3511975 spoVAD 7764890 spoVAD Clostridium botulinum A2 str. Kyoto stage V sporulation protein AD YP_002805605.1 3510968 R 536232 CDS YP_002805606.1 226950515 7765732 complement(3511998..3512453) 1 NC_012563.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02838; stage V sporulation protein AC 3512453 spoVAC 7765732 spoVAC Clostridium botulinum A2 str. Kyoto stage V sporulation protein AC YP_002805606.1 3511998 R 536232 CDS YP_002805607.1 226950516 7767045 complement(3512655..3513410) 1 NC_012563.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the prespore at the onset of sporulation. Interaction with spoIIAB inhibits sigma F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore.; sporulation sigma factor SigF 3513410 sigF 7767045 sigF Clostridium botulinum A2 str. Kyoto sporulation sigma factor SigF YP_002805607.1 3512655 R 536232 CDS YP_002805608.1 226950517 7767960 complement(3513429..3513851) 1 NC_012563.1 binds to sigma F preventing its association with RNA polymerase during sporulation; anti-sigma F factor 3513851 spoIIAB 7767960 spoIIAB Clostridium botulinum A2 str. Kyoto anti-sigma F factor YP_002805608.1 3513429 R 536232 CDS YP_002805609.1 226950518 7765400 complement(3513868..3514203) 1 NC_012563.1 identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; match to protein family HMM TIGR02886; anti-sigma F factor antagonist 3514203 spoIIAA 7765400 spoIIAA Clostridium botulinum A2 str. Kyoto anti-sigma F factor antagonist YP_002805609.1 3513868 R 536232 CDS YP_002805610.1 226950519 7766551 3514304..3514474 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; spermidine synthase 3514474 7766551 CLM_3495 Clostridium botulinum A2 str. Kyoto spermidine synthase YP_002805610.1 3514304 D 536232 CDS YP_002805611.1 226950520 7766458 complement(3514758..3516491) 1 NC_012563.1 modification methylase family protein 3516491 7766458 CLM_3496 Clostridium botulinum A2 str. Kyoto modification methylase family protein YP_002805611.1 3514758 R 536232 CDS YP_002805612.1 226950521 7767141 3516558..3517532 1 NC_012563.1 identified by match to protein family HMM PF01522; match to protein family HMM TIGR02884; polysaccharide deacetylase family protein 3517532 7767141 CLM_3497 Clostridium botulinum A2 str. Kyoto polysaccharide deacetylase family protein YP_002805612.1 3516558 D 536232 CDS YP_002805613.1 226950522 7767668 complement(3517623..3518339) 1 NC_012563.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696; glycosyl transferase, WecB/TagA/CpsF family 3518339 7767668 CLM_3498 Clostridium botulinum A2 str. Kyoto glycosyl transferase, WecB/TagA/CpsF family YP_002805613.1 3517623 R 536232 CDS YP_002805614.1 226950523 7765309 complement(3518668..3519321) 1 NC_012563.1 identified by match to protein family HMM PF02397; sugar transferase family protein 3519321 7765309 CLM_3499 Clostridium botulinum A2 str. Kyoto sugar transferase family protein YP_002805614.1 3518668 R 536232 CDS YP_002805615.1 226950524 7766922 complement(3519332..3520756) 1 NC_012563.1 identified by match to protein family HMM PF01943; transporter 3520756 7766922 CLM_3500 Clostridium botulinum A2 str. Kyoto transporter YP_002805615.1 3519332 R 536232 CDS YP_002805616.1 226950525 7767504 complement(3521154..3522710) 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023; match to protein family HMM TIGR01695; integral membrane protein MviN 3522710 mviN 7767504 mviN Clostridium botulinum A2 str. Kyoto integral membrane protein MviN YP_002805616.1 3521154 R 536232 CDS YP_002805617.1 226950526 7764450 complement(3522729..3523832) 1 NC_012563.1 identified by match to protein family HMM PF00534; group 1 glycosyl transferase family 3523832 7764450 CLM_3502 Clostridium botulinum A2 str. Kyoto group 1 glycosyl transferase family YP_002805617.1 3522729 R 536232 CDS YP_002805618.1 226950527 7766656 complement(3523941..3525068) 1 NC_012563.1 identified by match to protein family HMM PF00534; group 1 glycosyl transferase family 3525068 7766656 CLM_3503 Clostridium botulinum A2 str. Kyoto group 1 glycosyl transferase family YP_002805618.1 3523941 R 536232 CDS YP_002805619.1 226950528 7767532 complement(3525183..3526415) 1 NC_012563.1 identified by match to protein family HMM PF04932; exopolysaccharide biosynthesis family protein 3526415 7767532 CLM_3504 Clostridium botulinum A2 str. Kyoto exopolysaccharide biosynthesis family protein YP_002805619.1 3525183 R 536232 CDS YP_002805620.1 226950529 7767894 complement(3526493..3527719) 1 NC_012563.1 identified by match to protein family HMM PF00534; group 1 glycosyl transferase family 3527719 7767894 CLM_3505 Clostridium botulinum A2 str. Kyoto group 1 glycosyl transferase family YP_002805620.1 3526493 R 536232 CDS YP_002805621.1 226950530 7767369 complement(3527738..3528796) 1 NC_012563.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase 3528796 7767369 CLM_3506 Clostridium botulinum A2 str. Kyoto UDP-N-acetylglucosamine 2-epimerase YP_002805621.1 3527738 R 536232 CDS YP_002805622.1 226950531 7765709 complement(3528796..3529890) 1 NC_012563.1 identified by match to protein family HMM PF00534; group 1 glycosyl transferase family 3529890 7765709 CLM_3507 Clostridium botulinum A2 str. Kyoto group 1 glycosyl transferase family YP_002805622.1 3528796 R 536232 CDS YP_002805623.1 226950532 7767044 complement(3529913..3531016) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3531016 7767044 CLM_3508 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805623.1 3529913 R 536232 CDS YP_002805624.1 226950533 7767638 complement(3531006..3532424) 1 NC_012563.1 hypothetical protein 3532424 7767638 CLM_3509 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805624.1 3531006 R 536232 CDS YP_002805625.1 226950534 7764754 complement(3532439..3533533) 1 NC_012563.1 identified by match to protein family HMM PF00560; putative internalin 3533533 7764754 CLM_3510 Clostridium botulinum A2 str. Kyoto putative internalin YP_002805625.1 3532439 R 536232 CDS YP_002805626.1 226950535 7765181 complement(3533570..3534877) 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; polysaccharide biosynthesis protein 3534877 7765181 CLM_3511 Clostridium botulinum A2 str. Kyoto polysaccharide biosynthesis protein YP_002805626.1 3533570 R 536232 CDS YP_002805627.1 226950536 7766527 complement(3534908..3535654) 1 NC_012563.1 identified by match to protein family HMM PF00132; putative acetyltransferase 3535654 7766527 CLM_3512 Clostridium botulinum A2 str. Kyoto putative acetyltransferase YP_002805627.1 3534908 R 536232 CDS YP_002805628.1 226950537 7765132 complement(3535754..3536863) 1 NC_012563.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447; NAD-binding Rossmann fold family oxidoreductase 3536863 7765132 CLM_3513 Clostridium botulinum A2 str. Kyoto NAD-binding Rossmann fold family oxidoreductase YP_002805628.1 3535754 R 536232 CDS YP_002805629.1 226950538 7765866 complement(3536927..3538243) 1 NC_012563.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03446; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; UDP-glucose/GDP-mannose dehydrogenase family 3538243 7765866 CLM_3514 Clostridium botulinum A2 str. Kyoto UDP-glucose/GDP-mannose dehydrogenase family YP_002805629.1 3536927 R 536232 CDS YP_002805630.1 226950539 7765315 complement(3538373..3540238) 1 NC_012563.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; exopolysaccharide biosynthesis protein 3540238 7765315 CLM_3515 Clostridium botulinum A2 str. Kyoto exopolysaccharide biosynthesis protein YP_002805630.1 3538373 R 536232 CDS YP_002805631.1 226950540 7764871 complement(3540418..3543309) 1 NC_012563.1 identified by match to protein family HMM PF01520; match to protein family HMM PF07495; putative N-acetylmuramoyl-L-alanine amidase 3543309 7764871 CLM_3516 Clostridium botulinum A2 str. Kyoto putative N-acetylmuramoyl-L-alanine amidase YP_002805631.1 3540418 R 536232 CDS YP_002805632.1 226950541 7767980 complement(3543504..3546098) 1 NC_012563.1 identified by match to protein family HMM PF01520; match to protein family HMM PF07495; N-acetylmuramoyl-L-alanine amidase 3546098 7767980 CLM_3517 Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase YP_002805632.1 3543504 R 536232 CDS YP_002805633.1 226950542 7766966 complement(3546276..3549740) 1 NC_012563.1 identified by match to protein family HMM PF01832; match to protein family HMM PF07495; N-acetylmuramoyl-L-alanine amidase 3549740 7766966 CLM_3518 Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase YP_002805633.1 3546276 R 536232 CDS YP_002805634.1 226950543 7766969 complement(3549839..3550735) 1 NC_012563.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099; UTP-glucose-1-phosphate uridylyltransferase 3550735 galU 7766969 galU Clostridium botulinum A2 str. Kyoto UTP-glucose-1-phosphate uridylyltransferase YP_002805634.1 3549839 R 536232 CDS YP_002805635.1 226950544 7765319 complement(3550785..3551861) 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; TPR domain-containing protein 3551861 7765319 CLM_3520 Clostridium botulinum A2 str. Kyoto TPR domain-containing protein YP_002805635.1 3550785 R 536232 CDS YP_002805636.1 226950545 7764560 complement(3552006..3553733) 1 NC_012563.1 identified by match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphoglucomutase/phosphomannomutase family protein 3553733 7764560 CLM_3521 Clostridium botulinum A2 str. Kyoto phosphoglucomutase/phosphomannomutase family protein YP_002805636.1 3552006 R 536232 CDS YP_002805637.1 226950546 7767371 complement(3554374..3554910) 1 NC_012563.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 3554910 7767371 CLM_3522 Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L25/general stress protein Ctc YP_002805637.1 3554374 R 536232 CDS YP_002805638.1 226950547 7767451 3555117..3556577 1 NC_012563.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF01276; match to protein family HMM PF03711; match to protein family HMM PF05889; Orn/Lys/Arg decarboxylase 3556577 7767451 CLM_3523 Clostridium botulinum A2 str. Kyoto Orn/Lys/Arg decarboxylase YP_002805638.1 3555117 D 536232 CDS YP_002805639.1 226950548 7766574 complement(3556763..3557596) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3557596 7766574 CLM_3524 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805639.1 3556763 R 536232 CDS YP_002805640.1 226950549 7764755 complement(3557794..3558696) 1 NC_012563.1 identified by match to protein family HMM PF01515; phosphate acetyl/butyryl transferase 3558696 7764755 CLM_3525 Clostridium botulinum A2 str. Kyoto phosphate acetyl/butyryl transferase YP_002805640.1 3557794 R 536232 CDS YP_002805641.1 226950550 7765804 complement(3559159..3560172) 1 NC_012563.1 identified by match to protein family HMM PF01070; match to protein family HMM PF01180; dehydrogenase 3560172 7765804 CLM_3526 Clostridium botulinum A2 str. Kyoto dehydrogenase YP_002805641.1 3559159 R 536232 CDS YP_002805642.1 226950551 7766624 complement(3560408..3560878) 1 NC_012563.1 identified by match to protein family HMM PF04463; hypothetical protein 3560878 7766624 CLM_3527 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805642.1 3560408 R 536232 CDS YP_002805643.1 226950552 7767600 complement(3561066..3563432) 1 NC_012563.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein 3563432 7767600 CLM_3528 Clostridium botulinum A2 str. Kyoto recombination and DNA strand exchange inhibitor protein YP_002805643.1 3561066 R 536232 CDS YP_002805644.1 226950553 7767314 complement(3563565..3565931) 1 NC_012563.1 identified by match to protein family HMM PF01136; peptidase, U32 family 3565931 7767314 CLM_3529 Clostridium botulinum A2 str. Kyoto peptidase, U32 family YP_002805644.1 3563565 R 536232 CDS YP_002805645.1 226950554 7767930 complement(3566508..3567380) 1 NC_012563.1 hypothetical protein 3567380 7767930 CLM_3530 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805645.1 3566508 R 536232 CDS YP_002805646.1 226950555 7765052 3567585..3569360 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3569360 7765052 CLM_3531 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805646.1 3567585 D 536232 CDS YP_002805647.1 226950556 7766812 complement(3569531..3569683) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative; hypothetical protein 3569683 7766812 CLM_3532 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805647.1 3569531 R 536232 CDS YP_002805648.1 226950557 7766846 complement(3569863..3570129) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3570129 7766846 CLM_3533 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805648.1 3569863 R 536232 CDS YP_002805649.1 226950558 7767713 3570503..3570961 1 NC_012563.1 group 2 family glycosyl transferase 3570961 7767713 CLM_3535 Clostridium botulinum A2 str. Kyoto group 2 family glycosyl transferase YP_002805649.1 3570503 D 536232 CDS YP_002805650.1 226950559 7765038 complement(3570983..3571573) 1 NC_012563.1 identified by match to protein family HMM PF05164; hypothetical protein 3571573 7765038 CLM_3536 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805650.1 3570983 R 536232 CDS YP_002805651.1 226950560 7767860 complement(3571778..3574159) 1 NC_012563.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 3574159 pheT 7767860 pheT Clostridium botulinum A2 str. Kyoto phenylalanyl-tRNA synthetase subunit beta YP_002805651.1 3571778 R 536232 CDS YP_002805652.1 226950561 7766304 complement(3574320..3575339) 1 NC_012563.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 3575339 pheS 7766304 pheS Clostridium botulinum A2 str. Kyoto phenylalanyl-tRNA synthetase subunit alpha YP_002805652.1 3574320 R 536232 CDS YP_002805653.1 226950562 7765934 complement(3575687..3576466) 1 NC_012563.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; RNA methyltransferase, TrmH family 3576466 7765934 CLM_3539 Clostridium botulinum A2 str. Kyoto RNA methyltransferase, TrmH family YP_002805653.1 3575687 R 536232 CDS YP_002805654.1 226950563 7764302 complement(3576557..3577219) 1 NC_012563.1 identified by match to protein family HMM PF02080; match to protein family HMM PF02254; TrkA family potassium uptake protein 3577219 7764302 CLM_3540 Clostridium botulinum A2 str. Kyoto TrkA family potassium uptake protein YP_002805654.1 3576557 R 536232 CDS YP_002805655.1 226950564 7767403 complement(3577230..3578573) 1 NC_012563.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933; potassium uptake protein, TrkH family 3578573 7767403 CLM_3541 Clostridium botulinum A2 str. Kyoto potassium uptake protein, TrkH family YP_002805655.1 3577230 R 536232 CDS YP_002805656.1 226950565 7765811 complement(3578697..3579056) 1 NC_012563.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 3579056 rplT 7765811 rplT Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L20 YP_002805656.1 3578697 R 536232 CDS YP_002805657.1 226950566 7764725 complement(3579086..3579283) 1 NC_012563.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 3579283 rpmI 7764725 rpmI Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L35 YP_002805657.1 3579086 R 536232 CDS YP_002805658.1 226950567 7767994 complement(3579305..3579859) 1 NC_012563.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 3579859 infC 7767994 infC Clostridium botulinum A2 str. Kyoto translation initiation factor IF-3 YP_002805658.1 3579305 R 536232 CDS YP_002805659.1 226950568 7767122 complement(3580114..3582021) 1 NC_012563.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 3582021 thrS 7767122 thrS Clostridium botulinum A2 str. Kyoto threonyl-tRNA synthetase YP_002805659.1 3580114 R 536232 CDS YP_002805660.1 226950569 7765221 complement(3582369..3583268) 1 NC_012563.1 identified by match to protein family HMM PF08812; match to protein family HMM TIGR02834; putative sporulation protein YtxC 3583268 7765221 CLM_3547 Clostridium botulinum A2 str. Kyoto putative sporulation protein YtxC YP_002805660.1 3582369 R 536232 CDS YP_002805661.1 226950570 7765749 3583423..3584130 1 NC_012563.1 hypothetical protein 3584130 7765749 CLM_3548 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805661.1 3583423 D 536232 CDS YP_002805662.1 226950571 7764667 complement(3584338..3585909) 1 NC_012563.1 ABC transporter permease 3585909 7764667 CLM_3549 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002805662.1 3584338 R 536232 CDS YP_002805663.1 226950572 7767491 complement(3585911..3586606) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3586606 7767491 CLM_3550 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002805663.1 3585911 R 536232 CDS YP_002805664.1 226950573 7768191 complement(3587386..3588276) 1 NC_012563.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3588276 hslO 7768191 hslO Clostridium botulinum A2 str. Kyoto Hsp33-like chaperonin YP_002805664.1 3587386 R 536232 CDS YP_002805665.1 226950574 7766035 complement(3588314..3589054) 1 NC_012563.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; hypothetical protein 3589054 7766035 CLM_3557 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805665.1 3588314 R 536232 CDS YP_002805666.1 226950575 7767436 complement(3589140..3589412) 1 NC_012563.1 small acid-soluble spore protein 3589412 7767436 CLM_3558 Clostridium botulinum A2 str. Kyoto small acid-soluble spore protein YP_002805666.1 3589140 R 536232 CDS YP_002805667.1 226950576 7766582 complement(3589722..3590681) 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; peptide ABC transporter ATP-binding protein 3590681 7766582 CLM_3559 Clostridium botulinum A2 str. Kyoto peptide ABC transporter ATP-binding protein YP_002805667.1 3589722 R 536232 CDS YP_002805668.1 226950577 7765813 complement(3590681..3591700) 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; peptide ABC transporter ATP-binding protein 3591700 7765813 CLM_3560 Clostridium botulinum A2 str. Kyoto peptide ABC transporter ATP-binding protein YP_002805668.1 3590681 R 536232 CDS YP_002805669.1 226950578 7764778 complement(3591715..3592632) 1 NC_012563.1 identified by match to protein family HMM PF00528; peptide ABC transporter permease 3592632 7764778 CLM_3561 Clostridium botulinum A2 str. Kyoto peptide ABC transporter permease YP_002805669.1 3591715 R 536232 CDS YP_002805670.1 226950579 7768068 complement(3592648..3593577) 1 NC_012563.1 identified by match to protein family HMM PF00528; peptide ABC transporter permease 3593577 7768068 CLM_3562 Clostridium botulinum A2 str. Kyoto peptide ABC transporter permease YP_002805670.1 3592648 R 536232 CDS YP_002805671.1 226950580 7765735 complement(3593658..3595340) 1 NC_012563.1 identified by match to protein family HMM PF00496; peptide ABC transporter substrate-binding protein 3595340 7765735 CLM_3563 Clostridium botulinum A2 str. Kyoto peptide ABC transporter substrate-binding protein YP_002805671.1 3593658 R 536232 CDS YP_002805672.1 226950581 7765825 3595824..3596816 1 NC_012563.1 identified by match to protein family HMM PF01118; match to protein family HMM PF02774; match to protein family HMM TIGR01296; aspartate-semialdehyde dehydrogenase 3596816 asd 7765825 asd Clostridium botulinum A2 str. Kyoto aspartate-semialdehyde dehydrogenase YP_002805672.1 3595824 D 536232 CDS YP_002805673.1 226950582 7764721 3596839..3597717 1 NC_012563.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 3597717 dapA 7764721 dapA Clostridium botulinum A2 str. Kyoto dihydrodipicolinate synthase YP_002805673.1 3596839 D 536232 CDS YP_002805674.1 226950583 7766641 3597940..3598695 1 NC_012563.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 3598695 dapB 7766641 dapB Clostridium botulinum A2 str. Kyoto dihydrodipicolinate reductase YP_002805674.1 3597940 D 536232 CDS YP_002805675.1 226950584 7765497 complement(3599009..3600172) 1 NC_012563.1 identified by similarity to SP:P16524; match to protein family HMM PF00155; class I/II aminotransferase 3600172 7765497 CLM_3567 Clostridium botulinum A2 str. Kyoto class I/II aminotransferase YP_002805675.1 3599009 R 536232 CDS YP_002805676.1 226950585 7767806 3600430..3601140 1 NC_012563.1 identified by match to protein family HMM PF00132; match to protein family HMM PF08503; match to protein family HMM TIGR03532; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 3601140 7767806 CLM_3568 Clostridium botulinum A2 str. Kyoto 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase YP_002805676.1 3600430 D 536232 CDS YP_002805677.1 226950586 7766441 complement(3601256..3601957) 1 NC_012563.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 3601957 7766441 CLM_3569 Clostridium botulinum A2 str. Kyoto single-stranded DNA-binding protein YP_002805677.1 3601256 R 536232 CDS YP_002805678.1 226950587 7765970 complement(3602035..3602532) 1 NC_012563.1 hypothetical protein 3602532 7765970 CLM_3570 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805678.1 3602035 R 536232 CDS YP_002805679.1 226950588 7764717 complement(3602731..3603483) 1 NC_012563.1 identified by match to protein family HMM PF01522; match to protein family HMM TIGR02764; polysaccharide deacetylase family protein 3603483 7764717 CLM_3571 Clostridium botulinum A2 str. Kyoto polysaccharide deacetylase family protein YP_002805679.1 3602731 R 536232 CDS YP_002805680.1 226950589 7767649 3603647..3604174 1 NC_012563.1 hypothetical protein 3604174 7767649 CLM_3572 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805680.1 3603647 D 536232 CDS YP_002805681.1 226950590 7766606 complement(3604177..3605061) 1 NC_012563.1 hypothetical protein 3605061 7766606 CLM_3573 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805681.1 3604177 R 536232 CDS YP_002805682.1 226950591 7768118 3605201..3605461 1 NC_012563.1 hypothetical protein 3605461 7768118 CLM_3574 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805682.1 3605201 D 536232 CDS YP_002805683.1 226950592 7764840 complement(3605470..3606759) 1 NC_012563.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; FolC bifunctional protein 3606759 folC 7764840 folC Clostridium botulinum A2 str. Kyoto FolC bifunctional protein YP_002805683.1 3605470 R 536232 CDS YP_002805684.1 226950593 7764419 complement(3607205..3609850) 1 NC_012563.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 3609850 valS 7764419 valS Clostridium botulinum A2 str. Kyoto valyl-tRNA synthetase YP_002805684.1 3607205 R 536232 CDS YP_002805685.1 226950594 7765224 complement(3609871..3610377) 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 3610377 7765224 CLM_3577 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002805685.1 3609871 R 536232 CDS YP_002805686.1 226950595 7766580 complement(3610831..3611586) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3611586 7766580 CLM_3578 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002805686.1 3610831 R 536232 CDS YP_002805687.1 226950596 7767502 complement(3611589..3614084) 1 NC_012563.1 putative ABC transporter permease 3614084 7767502 CLM_3579 Clostridium botulinum A2 str. Kyoto putative ABC transporter permease YP_002805687.1 3611589 R 536232 CDS YP_002805688.1 226950597 7766524 3614506..3615534 1 NC_012563.1 identified by match to protein family HMM PF09084; putative ABC transporter substrate-binding protein 3615534 7766524 CLM_3580 Clostridium botulinum A2 str. Kyoto putative ABC transporter substrate-binding protein YP_002805688.1 3614506 D 536232 CDS YP_002805689.1 226950598 7767418 complement(3615895..3620187) 1 NC_012563.1 identified by match to protein family HMM PF01869; match to protein family HMM TIGR00241; putative CoA-substrate-specific enzyme activase 3620187 7767418 CLM_3581 Clostridium botulinum A2 str. Kyoto putative CoA-substrate-specific enzyme activase YP_002805689.1 3615895 R 536232 CDS YP_002805690.1 226950599 7765065 3620509..3621270 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3621270 7765065 CLM_3582 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002805690.1 3620509 D 536232 CDS YP_002805691.1 226950600 7767729 3621267..3622070 1 NC_012563.1 identified by match to protein family HMM PF00528; ABC transporter permease 3622070 7767729 CLM_3583 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002805691.1 3621267 D 536232 CDS YP_002805692.1 226950601 7764456 3622214..3622561 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07720; TPR domain-containing protein 3622561 7764456 CLM_3584 Clostridium botulinum A2 str. Kyoto TPR domain-containing protein YP_002805692.1 3622214 D 536232 CDS YP_002805693.1 226950602 7767368 complement(3622684..3623859) 1 NC_012563.1 identified by match to protein family HMM PF01841; transglutaminase domain-containing protein 3623859 7767368 CLM_3585 Clostridium botulinum A2 str. Kyoto transglutaminase domain-containing protein YP_002805693.1 3622684 R 536232 CDS YP_002805694.1 226950603 7768067 complement(3623884..3624819) 1 NC_012563.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 3624819 recX 7768067 recX Clostridium botulinum A2 str. Kyoto recombination regulator RecX YP_002805694.1 3623884 R 536232 CDS YP_002805695.1 226950604 7766977 complement(3624841..3626070) 1 NC_012563.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16 family 3626070 7766977 CLM_3587 Clostridium botulinum A2 str. Kyoto peptidase, M16 family YP_002805695.1 3624841 R 536232 CDS YP_002805696.1 226950605 7765778 3626291..3626794 1 NC_012563.1 identified by match to protein family HMM PF06177; hypothetical protein 3626794 7765778 CLM_3589 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805696.1 3626291 D 536232 CDS YP_002805697.1 226950606 7764736 3626832..3627419 1 NC_012563.1 identified by match to protein family HMM PF01613; putative flavin reductase 3627419 7764736 CLM_3590 Clostridium botulinum A2 str. Kyoto putative flavin reductase YP_002805697.1 3626832 D 536232 CDS YP_002805698.1 226950607 7767607 3627477..3628172 1 NC_012563.1 identified by match to protein family HMM PF01471; match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 3628172 7767607 CLM_3591 Clostridium botulinum A2 str. Kyoto ErfK/YbiS/YcfS/YnhG family protein YP_002805698.1 3627477 D 536232 CDS YP_002805699.1 226950608 7766503 complement(3628207..3629082) 1 NC_012563.1 hypothetical protein 3629082 7766503 CLM_3592 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805699.1 3628207 R 536232 CDS YP_002805700.1 226950609 7767593 complement(3629124..3629402) 1 NC_012563.1 identified by match to protein family HMM PF06865; hypothetical protein 3629402 7767593 CLM_3593 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805700.1 3629124 R 536232 CDS YP_002805701.1 226950610 7765384 complement(3629531..3630337) 1 NC_012563.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 3630337 proC 7765384 proC Clostridium botulinum A2 str. Kyoto pyrroline-5-carboxylate reductase YP_002805701.1 3629531 R 536232 CDS YP_002805702.1 226950611 7768027 complement(3630449..3632812) 1 NC_012563.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; formate acetyltransferase 3632812 7768027 CLM_3595 Clostridium botulinum A2 str. Kyoto formate acetyltransferase YP_002805702.1 3630449 R 536232 CDS YP_002805703.1 226950612 7766941 complement(3632815..3633720) 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF04055; match to protein family HMM TIGR02494; glycyl-radical enzyme activating family protein 3633720 7766941 CLM_3596 Clostridium botulinum A2 str. Kyoto glycyl-radical enzyme activating family protein YP_002805703.1 3632815 R 536232 CDS YP_002805704.1 226950613 7768018 complement(3633772..3634341) 1 NC_012563.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883; DNA-binding protein 3634341 7768018 CLM_3597 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002805704.1 3633772 R 536232 CDS YP_002805705.1 226950614 7767148 complement(3634977..3635705) 1 NC_012563.1 identified by match to protein family HMM PF00533; BRCT domain-containing protein 3635705 7767148 CLM_3598 Clostridium botulinum A2 str. Kyoto BRCT domain-containing protein YP_002805705.1 3634977 R 536232 CDS YP_002805706.1 226950615 7765766 complement(3635742..3636083) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3636083 7765766 CLM_3599 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805706.1 3635742 R 536232 CDS YP_002805707.1 226950616 7764856 complement(3636095..3637831) 1 NC_012563.1 identified by match to protein family HMM PF00092; von Willebrand factor type A domain-containing protein 3637831 7764856 CLM_3600 Clostridium botulinum A2 str. Kyoto von Willebrand factor type A domain-containing protein YP_002805707.1 3636095 R 536232 CDS YP_002805708.1 226950617 7767204 complement(3637854..3639182) 1 NC_012563.1 identified by match to protein family HMM PF07728; ATPase, AAA family 3639182 7767204 CLM_3601 Clostridium botulinum A2 str. Kyoto ATPase, AAA family YP_002805708.1 3637854 R 536232 CDS YP_002805709.1 226950618 7766622 3639805..3640881 1 NC_012563.1 hypothetical protein 3640881 7766622 CLM_3602 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805709.1 3639805 D 536232 CDS YP_002805710.1 226950619 7764933 3640950..3642035 1 NC_012563.1 hypothetical protein 3642035 7764933 CLM_3603 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805710.1 3640950 D 536232 CDS YP_002805711.1 226950620 7768125 complement(3642214..3642408) 1 NC_012563.1 iron-sulfur cluster-binding protein 3642408 7768125 CLM_3604 Clostridium botulinum A2 str. Kyoto iron-sulfur cluster-binding protein YP_002805711.1 3642214 R 536232 CDS YP_002805712.1 226950621 7764485 3642651..3643544 1 NC_012563.1 hypothetical protein 3643544 7764485 CLM_3605 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805712.1 3642651 D 536232 CDS YP_002805713.1 226950622 7765785 3643547..3644644 1 NC_012563.1 identified by similarity to GB:EDK33626.1; hypothetical protein 3644644 7765785 CLM_3606 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805713.1 3643547 D 536232 CDS YP_002805714.1 226950623 7766205 3644625..3645599 1 NC_012563.1 identified by match to protein family HMM PF01869; match to protein family HMM TIGR00241; putative CoA-substrate-specific enzyme activase 3645599 7766205 CLM_3607 Clostridium botulinum A2 str. Kyoto putative CoA-substrate-specific enzyme activase YP_002805714.1 3644625 D 536232 CDS YP_002805715.1 226950624 7767582 complement(3645663..3647291) 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; sigma-54 dependent transcriptional regulator 3647291 7767582 CLM_3608 Clostridium botulinum A2 str. Kyoto sigma-54 dependent transcriptional regulator YP_002805715.1 3645663 R 536232 CDS YP_002805716.1 226950625 7766041 complement(3647649..3648656) 1 NC_012563.1 identified by match to protein family HMM PF00766; match to protein family HMM PF01012; electron transfer flavoprotein subunit alpha/FixB family protein 3648656 7766041 CLM_3609 Clostridium botulinum A2 str. Kyoto electron transfer flavoprotein subunit alpha/FixB family protein YP_002805716.1 3647649 R 536232 CDS YP_002805717.1 226950626 7766702 complement(3648669..3649448) 1 NC_012563.1 identified by match to protein family HMM PF01012; electron transfer flavoprotein subunit beta/FixA family protein 3649448 7766702 CLM_3610 Clostridium botulinum A2 str. Kyoto electron transfer flavoprotein subunit beta/FixA family protein YP_002805717.1 3648669 R 536232 CDS YP_002805718.1 226950627 7764290 complement(3649460..3650599) 1 NC_012563.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; butyryl-CoA dehydrogenase 3650599 bcd 7764290 bcd Clostridium botulinum A2 str. Kyoto butyryl-CoA dehydrogenase YP_002805718.1 3649460 R 536232 CDS YP_002805719.1 226950628 7764931 complement(3650793..3651971) 1 NC_012563.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 3651971 7764931 CLM_3612 Clostridium botulinum A2 str. Kyoto acetyl-CoA acetyltransferase YP_002805719.1 3650793 R 536232 CDS YP_002805720.1 226950629 7765563 complement(3651996..3652826) 1 NC_012563.1 identified by match to protein family HMM PF00725; match to protein family HMM PF02737; 3-hydroxybutyryl-CoA dehydrogenase 3652826 hbd 7765563 hbd Clostridium botulinum A2 str. Kyoto 3-hydroxybutyryl-CoA dehydrogenase YP_002805720.1 3651996 R 536232 CDS YP_002805721.1 226950630 7765597 complement(3652846..3653628) 1 NC_012563.1 identified by match to protein family HMM PF00378; 3-hydroxybutyryl-CoA dehydratase 3653628 crt 7765597 crt Clostridium botulinum A2 str. Kyoto 3-hydroxybutyryl-CoA dehydratase YP_002805721.1 3652846 R 536232 CDS YP_002805722.1 226950631 7768021 complement(3654044..3654262) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3654262 7768021 CLM_3615 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805722.1 3654044 R 536232 CDS YP_002805723.1 226950632 7764803 complement(3654306..3655403) 1 NC_012563.1 identified by match to protein family HMM PF01541; GIY-YIG domain-containing protein 3655403 7764803 CLM_3616 Clostridium botulinum A2 str. Kyoto GIY-YIG domain-containing protein YP_002805723.1 3654306 R 536232 CDS YP_002805724.1 226950633 7765119 complement(3655679..3656971) 1 NC_012563.1 identified by match to protein family HMM PF00860; xanthine/uracil permease family protein 3656971 7765119 CLM_3617 Clostridium botulinum A2 str. Kyoto xanthine/uracil permease family protein YP_002805724.1 3655679 R 536232 CDS YP_002805725.1 226950634 7765989 complement(3657373..3658269) 1 NC_012563.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; HDIG domain-containing protein 3658269 7765989 CLM_3618 Clostridium botulinum A2 str. Kyoto HDIG domain-containing protein YP_002805725.1 3657373 R 536232 CDS YP_002805726.1 226950635 7766428 complement(3658337..3658489) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3658489 7766428 CLM_3619 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805726.1 3658337 R 536232 CDS YP_002805727.1 226950636 7767296 complement(3658877..3659641) 1 NC_012563.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3659641 lgt 7767296 lgt Clostridium botulinum A2 str. Kyoto prolipoprotein diacylglyceryl transferase YP_002805727.1 3658877 R 536232 CDS YP_002805728.1 226950637 7766799 complement(3659850..3660314) 1 NC_012563.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; phosphodiesterase 3660314 7766799 CLM_3621 Clostridium botulinum A2 str. Kyoto phosphodiesterase YP_002805728.1 3659850 R 536232 CDS YP_002805729.1 226950638 7767725 complement(3660357..3660722) 1 NC_012563.1 hypothetical protein 3660722 7767725 CLM_3622 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805729.1 3660357 R 536232 CDS YP_002805730.1 226950639 7764802 3660853..3661608 1 NC_012563.1 identified by match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase family protein 3661608 7764802 CLM_3623 Clostridium botulinum A2 str. Kyoto glycerophosphoryl diester phosphodiesterase family protein YP_002805730.1 3660853 D 536232 CDS YP_002805731.1 226950640 7766658 complement(3661704..3663710) 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743; methyl-accepting chemotaxis protein 3663710 7766658 CLM_3624 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002805731.1 3661704 R 536232 CDS YP_002805732.1 226950641 7765290 complement(3663905..3664450) 1 NC_012563.1 identified by match to protein family HMM PF00301; match to protein family HMM PF02915; rubredoxin/rubrerythrin 3664450 7765290 CLM_3625 Clostridium botulinum A2 str. Kyoto rubredoxin/rubrerythrin YP_002805732.1 3663905 R 536232 CDS YP_002805733.1 226950642 7764218 complement(3665092..3665790) 1 NC_012563.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02493; pyruvate formate-lyase activating enzyme 3665790 pflA 7764218 pflA Clostridium botulinum A2 str. Kyoto pyruvate formate-lyase activating enzyme YP_002805733.1 3665092 R 536232 CDS YP_002805734.1 226950643 7768033 complement(3665970..3668198) 1 NC_012563.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase 1 3668198 pfl 7768033 pfl Clostridium botulinum A2 str. Kyoto formate acetyltransferase 1 YP_002805734.1 3665970 R 536232 CDS YP_002805735.1 226950644 7766046 complement(3668711..3668962) 1 NC_012563.1 hypothetical protein 3668962 7766046 CLM_3628 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805735.1 3668711 R 536232 CDS YP_002805736.1 226950645 7765109 complement(3669339..3669908) 1 NC_012563.1 identified by match to protein family HMM PF01386; match to protein family HMM TIGR00731; ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 3669908 7765109 CLM_3629 Clostridium botulinum A2 str. Kyoto ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 YP_002805736.1 3669339 R 536232 CDS YP_002805737.1 226950646 7767727 complement(3670075..3670689) 1 NC_012563.1 putative lipoprotein 3670689 7767727 CLM_3630 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002805737.1 3670075 R 536232 CDS YP_002805738.1 226950647 7767602 3670915..3671343 1 NC_012563.1 identified by match to protein family HMM PF01475; Fur family transcriptional regulator 3671343 7767602 CLM_3631 Clostridium botulinum A2 str. Kyoto Fur family transcriptional regulator YP_002805738.1 3670915 D 536232 CDS YP_002805739.1 226950648 7767629 complement(3671412..3672647) 1 NC_012563.1 identified by match to protein family HMM PF01547; extracellular solute-binding protein 3672647 7767629 CLM_3632 Clostridium botulinum A2 str. Kyoto extracellular solute-binding protein YP_002805739.1 3671412 R 536232 CDS YP_002805740.1 226950649 7766481 3672748..3673683 1 NC_012563.1 hypothetical protein 3673683 7766481 CLM_3633 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805740.1 3672748 D 536232 CDS YP_002805741.1 226950650 7767580 complement(3673843..3674799) 1 NC_012563.1 identified by match to protein family HMM PF08279; hypothetical protein 3674799 7767580 CLM_3634 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805741.1 3673843 R 536232 CDS YP_002805742.1 226950651 7764228 complement(3675014..3675436) 1 NC_012563.1 hypothetical protein 3675436 7764228 CLM_3635 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805742.1 3675014 R 536232 CDS YP_002805743.1 226950652 7766968 complement(3675491..3675736) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3675736 7766968 CLM_3636 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805743.1 3675491 R 536232 CDS YP_002805744.1 226950653 7766370 complement(3675788..3676216) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3676216 7766370 CLM_3637 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805744.1 3675788 R 536232 CDS YP_002805745.1 226950654 7768077 complement(3676435..3677160) 1 NC_012563.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family protein 3677160 7768077 CLM_3638 Clostridium botulinum A2 str. Kyoto CAAX amino terminal protease family protein YP_002805745.1 3676435 R 536232 CDS YP_002805746.1 226950655 7764964 complement(3677184..3677768) 1 NC_012563.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 3677768 engB 7764964 engB Clostridium botulinum A2 str. Kyoto ribosome biogenesis GTP-binding protein YsxC YP_002805746.1 3677184 R 536232 CDS YP_002805747.1 226950656 7765505 complement(3677783..3680104) 1 NC_012563.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763; endopeptidase LA 3680104 lon 7765505 lon Clostridium botulinum A2 str. Kyoto endopeptidase LA YP_002805747.1 3677783 R 536232 CDS YP_002805748.1 226950657 7766901 complement(3680242..3681921) 1 NC_012563.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01078; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR02902; ATP-dependent protease LonB 3681921 lonB 7766901 lonB Clostridium botulinum A2 str. Kyoto ATP-dependent protease LonB YP_002805748.1 3680242 R 536232 CDS YP_002805749.1 226950658 7766473 complement(3682049..3683338) 1 NC_012563.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 3683338 clpX 7766473 clpX Clostridium botulinum A2 str. Kyoto ATP-dependent protease ATP-binding subunit ClpX YP_002805749.1 3682049 R 536232 CDS YP_002805750.1 226950659 7767574 complement(3683358..3683942) 1 NC_012563.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 3683942 clpP 7767574 clpP Clostridium botulinum A2 str. Kyoto ATP-dependent Clp protease proteolytic subunit YP_002805750.1 3683358 R 536232 CDS YP_002805751.1 226950660 7766449 complement(3684068..3685360) 1 NC_012563.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 3685360 tig 7766449 tig Clostridium botulinum A2 str. Kyoto trigger factor YP_002805751.1 3684068 R 536232 CDS YP_002805752.1 226950661 7767211 complement(3685538..3686323) 1 NC_012563.1 identified by match to protein family HMM PF01261; AP endonuclease 3686323 7767211 CLM_3645 Clostridium botulinum A2 str. Kyoto AP endonuclease YP_002805752.1 3685538 R 536232 CDS YP_002805753.1 226950662 7767897 complement(3686430..3687242) 1 NC_012563.1 hypothetical protein 3687242 7767897 CLM_3646 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805753.1 3686430 R 536232 CDS YP_002805754.1 226950663 7765533 complement(3687456..3688031) 1 NC_012563.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 3688031 pyrE 7765533 pyrE Clostridium botulinum A2 str. Kyoto orotate phosphoribosyltransferase YP_002805754.1 3687456 R 536232 CDS YP_002805755.1 226950664 7765913 complement(3688065..3688961) 1 NC_012563.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 3688961 pyrD 7765913 pyrD Clostridium botulinum A2 str. Kyoto dihydroorotate dehydrogenase 1B YP_002805755.1 3688065 R 536232 CDS YP_002805756.1 226950665 7766750 complement(3688961..3689716) 1 NC_012563.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit 3689716 pyrK 7766750 pyrK Clostridium botulinum A2 str. Kyoto dihydroorotate dehydrogenase electron transfer subunit YP_002805756.1 3688961 R 536232 CDS YP_002805757.1 226950666 7767178 complement(3689861..3690712) 1 NC_012563.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 3690712 pyrF 7767178 pyrF Clostridium botulinum A2 str. Kyoto orotidine 5'-phosphate decarboxylase YP_002805757.1 3689861 R 536232 CDS YP_002805758.1 226950667 7764324 complement(3690736..3691926) 1 NC_012563.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00857; dihydroorotase, multifunctional complex type 3691926 pyrC 7764324 pyrC Clostridium botulinum A2 str. Kyoto dihydroorotase, multifunctional complex type YP_002805758.1 3690736 R 536232 CDS YP_002805759.1 226950668 7765614 complement(3691948..3692388) 1 NC_012563.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 3692388 pyrI 7765614 pyrI Clostridium botulinum A2 str. Kyoto aspartate carbamoyltransferase regulatory subunit YP_002805759.1 3691948 R 536232 CDS YP_002805760.1 226950669 7766303 complement(3692390..3693313) 1 NC_012563.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 3693313 pyrB 7766303 pyrB Clostridium botulinum A2 str. Kyoto aspartate carbamoyltransferase catalytic subunit YP_002805760.1 3692390 R 536232 CDS YP_002805761.1 226950670 7767173 complement(3693568..3694326) 1 NC_012563.1 identified by similarity to SP:P11568; match to protein family HMM PF01869; match to protein family HMM TIGR00241; (R)-hydroxyglutaryl-CoA dehydratase activator 3694326 hgdC_2 7767173 hgdC_2 Clostridium botulinum A2 str. Kyoto (R)-hydroxyglutaryl-CoA dehydratase activator YP_002805761.1 3693568 R 536232 CDS YP_002805762.1 226950671 7766289 complement(3694349..3694546) 1 NC_012563.1 hypothetical protein 3694546 7766289 CLM_3656 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805762.1 3694349 R 536232 CDS YP_002805763.1 226950672 7764983 complement(3694906..3696165) 1 NC_012563.1 identified by match to protein family HMM PF06050; 2-hydroxyglutaryl-CoA dehydratase subunit D 3696165 7764983 CLM_3657 Clostridium botulinum A2 str. Kyoto 2-hydroxyglutaryl-CoA dehydratase subunit D YP_002805763.1 3694906 R 536232 CDS YP_002805764.1 226950673 7768097 complement(3696294..3697442) 1 NC_012563.1 identified by match to protein family HMM PF06050; 2-hydroxyglutaryl-CoA dehydratase subunit D 3697442 7768097 CLM_3658 Clostridium botulinum A2 str. Kyoto 2-hydroxyglutaryl-CoA dehydratase subunit D YP_002805764.1 3696294 R 536232 CDS YP_002805765.1 226950674 7766713 complement(3697554..3697886) 1 NC_012563.1 hypothetical protein 3697886 7766713 CLM_3659 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805765.1 3697554 R 536232 CDS YP_002805766.1 226950675 7765618 complement(3698053..3698811) 1 NC_012563.1 identified by match to protein family HMM PF00005; nitrate transport ATP-binding protein NrtD 3698811 7765618 CLM_3660 Clostridium botulinum A2 str. Kyoto nitrate transport ATP-binding protein NrtD YP_002805766.1 3698053 R 536232 CDS YP_002805767.1 226950676 7764577 complement(3698811..3698948) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3698948 7764577 CLM_3661 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805767.1 3698811 R 536232 CDS YP_002805768.1 226950677 7767163 complement(3698988..3699629) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00528; ABC transporter permease 3699629 7767163 CLM_3662 Clostridium botulinum A2 str. Kyoto ABC transporter permease YP_002805768.1 3698988 R 536232 CDS YP_002805769.1 226950678 7766339 complement(3699578..3700114) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer; putative; hypothetical protein 3700114 7766339 CLM_3663 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805769.1 3699578 R 536232 CDS YP_002805770.1 226950679 7764941 complement(3700166..3700384) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer; putative; hypothetical protein 3700384 7764941 CLM_3664 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805770.1 3700166 R 536232 CDS YP_002805771.1 226950680 7764954 complement(3700393..3700533) 1 NC_012563.1 hypothetical protein 3700533 7764954 CLM_3665 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805771.1 3700393 R 536232 CDS YP_002805772.1 226950681 7767982 complement(3700540..3701106) 1 NC_012563.1 hypothetical protein 3701106 7767982 CLM_3666 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805772.1 3700540 R 536232 CDS YP_002805773.1 226950682 7767086 complement(3701134..3702234) 1 NC_012563.1 putative lipoprotein 3702234 7767086 CLM_3667 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002805773.1 3701134 R 536232 CDS YP_002805774.1 226950683 7765849 complement(3702252..3702716) 1 NC_012563.1 putative lipoprotein 3702716 7765849 CLM_3668 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002805774.1 3702252 R 536232 CDS YP_002805775.1 226950684 7767512 complement(3702732..3703823) 1 NC_012563.1 identified by match to protein family HMM PF03773; putative permease 3703823 7767512 CLM_3669 Clostridium botulinum A2 str. Kyoto putative permease YP_002805775.1 3702732 R 536232 CDS YP_002805776.1 226950685 7766538 complement(3703823..3704083) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3704083 7766538 CLM_3670 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805776.1 3703823 R 536232 CDS YP_002805777.1 226950686 7768231 complement(3706641..3707111) 1 NC_012563.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; phosphodiesterase 3707111 7768231 CLM_3694 Clostridium botulinum A2 str. Kyoto phosphodiesterase YP_002805777.1 3706641 R 536232 CDS YP_002805778.1 226950687 7767986 complement(3707128..3707727) 1 NC_012563.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 3707727 7767986 CLM_3695 Clostridium botulinum A2 str. Kyoto putative deoxyribonucleotide triphosphate pyrophosphatase YP_002805778.1 3707128 R 536232 CDS YP_002805779.1 226950688 7766828 3707831..3709204 1 NC_012563.1 hypothetical protein 3709204 7766828 CLM_3696 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805779.1 3707831 D 536232 CDS YP_002805780.1 226950689 7766167 3709317..3709472 1 NC_012563.1 hypothetical protein 3709472 7766167 CLM_3697 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805780.1 3709317 D 536232 CDS YP_002805781.1 226950690 7767576 complement(3709475..3711037) 1 NC_012563.1 identified by match to protein family HMM PF00496; extracellular solute-binding protein 3711037 7767576 CLM_3698 Clostridium botulinum A2 str. Kyoto extracellular solute-binding protein YP_002805781.1 3709475 R 536232 CDS YP_002805782.1 226950691 7764905 complement(3711191..3712621) 1 NC_012563.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 3712621 gatB 7764905 gatB Clostridium botulinum A2 str. Kyoto aspartyl/glutamyl-tRNA amidotransferase subunit B YP_002805782.1 3711191 R 536232 CDS YP_002805783.1 226950692 7765750 complement(3712657..3714114) 1 NC_012563.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 3714114 gatA 7765750 gatA Clostridium botulinum A2 str. Kyoto aspartyl/glutamyl-tRNA amidotransferase subunit A YP_002805783.1 3712657 R 536232 CDS YP_002805784.1 226950693 7767092 complement(3714151..3714438) 1 NC_012563.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 3714438 gatC 7767092 gatC Clostridium botulinum A2 str. Kyoto aspartyl/glutamyl-tRNA amidotransferase subunit C YP_002805784.1 3714151 R 536232 CDS YP_002805785.1 226950694 7766398 complement(3714573..3715784) 1 NC_012563.1 identified by match to protein family HMM PF00375; sodium:dicarboxylate symporter family protein 3715784 7766398 CLM_3702 Clostridium botulinum A2 str. Kyoto sodium:dicarboxylate symporter family protein YP_002805785.1 3714573 R 536232 CDS YP_002805786.1 226950695 7767308 complement(3716169..3716438) 1 NC_012563.1 hypothetical protein 3716438 7767308 CLM_3703 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805786.1 3716169 R 536232 CDS YP_002805787.1 226950696 7764221 complement(3716539..3718533) 1 NC_012563.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 3718533 ligA 7764221 ligA Clostridium botulinum A2 str. Kyoto NAD-dependent DNA ligase LigA YP_002805787.1 3716539 R 536232 CDS YP_002805788.1 226950697 7765542 complement(3718545..3720761) 1 NC_012563.1 identified by match to protein family HMM PF00580; ATP-dependent DNA helicase PcrA 3720761 pcrA 7765542 pcrA Clostridium botulinum A2 str. Kyoto ATP-dependent DNA helicase PcrA YP_002805788.1 3718545 R 536232 CDS YP_002805789.1 226950698 7766869 complement(3720888..3721187) 1 NC_012563.1 identified by match to protein family HMM PF01371; match to protein family HMM TIGR02531; TrpR-like protein, YerC/YecD family 3721187 7766869 CLM_3706 Clostridium botulinum A2 str. Kyoto TrpR-like protein, YerC/YecD family YP_002805789.1 3720888 R 536232 CDS YP_002805790.1 226950699 7766000 complement(3721485..3722201) 1 NC_012563.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; RNA pseudouridine synthase family protein 3722201 7766000 CLM_3707 Clostridium botulinum A2 str. Kyoto RNA pseudouridine synthase family protein YP_002805790.1 3721485 R 536232 CDS YP_002805791.1 226950700 7766635 complement(3722285..3723001) 1 NC_012563.1 identified by match to protein family HMM PF01464; transglycosylase, SLT family 3723001 7766635 CLM_3708 Clostridium botulinum A2 str. Kyoto transglycosylase, SLT family YP_002805791.1 3722285 R 536232 CDS YP_002805792.1 226950701 7767285 complement(3723015..3725018) 1 NC_012563.1 identified by match to protein family HMM PF07495; triple tyrosine motif-containing protein 3725018 7767285 CLM_3709 Clostridium botulinum A2 str. Kyoto triple tyrosine motif-containing protein YP_002805792.1 3723015 R 536232 CDS YP_002805793.1 226950702 7767898 3725152..3725319 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3725319 7767898 CLM_3710 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805793.1 3725152 D 536232 CDS YP_002805794.1 226950703 7765415 complement(3725483..3725917) 1 NC_012563.1 identified by match to protein family HMM PF02639; hypothetical protein 3725917 7765415 CLM_3711 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805794.1 3725483 R 536232 CDS YP_002805795.1 226950704 7766040 complement(3725928..3727280) 1 NC_012563.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 3727280 pgi 7766040 pgi Clostridium botulinum A2 str. Kyoto glucose-6-phosphate isomerase YP_002805795.1 3725928 R 536232 CDS YP_002805796.1 226950705 7766669 complement(3727364..3727534) 1 NC_012563.1 hypothetical protein 3727534 7766669 CLM_3713 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805796.1 3727364 R 536232 CDS YP_002805797.1 226950706 7767940 complement(3727865..3728509) 1 NC_012563.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3728509 7767940 CLM_3714 Clostridium botulinum A2 str. Kyoto TetR family transcriptional regulator YP_002805797.1 3727865 R 536232 CDS YP_002805798.1 226950707 7764329 3728740..3729273 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 3729273 7764329 CLM_3715 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002805798.1 3728740 D 536232 CDS YP_002805799.1 226950708 7765198 3729817..3730821 1 NC_012563.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; D-lactate dehydrogenase 3730821 ldhA 7765198 ldhA Clostridium botulinum A2 str. Kyoto D-lactate dehydrogenase YP_002805799.1 3729817 D 536232 CDS YP_002805800.1 226950709 7764861 complement(3730996..3731991) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00389; match to protein family HMM PF02826; D-lactate dehydrogenase 3731991 ldhA 7764861 ldhA Clostridium botulinum A2 str. Kyoto D-lactate dehydrogenase YP_002805800.1 3730996 R 536232 CDS YP_002805801.1 226950710 7764289 complement(3732805..3733983) 1 NC_012563.1 hypothetical protein 3733983 7764289 CLM_3718 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805801.1 3732805 R 536232 CDS YP_002805802.1 226950711 7767614 complement(3734199..3735395) 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00766; match to protein family HMM PF01012; electron transfer flavoprotein subunit alpha/FixB family protein 3735395 7767614 CLM_3719 Clostridium botulinum A2 str. Kyoto electron transfer flavoprotein subunit alpha/FixB family protein YP_002805802.1 3734199 R 536232 CDS YP_002805803.1 226950712 7766030 complement(3735413..3736207) 1 NC_012563.1 identified by match to protein family HMM PF01012; electron transfer flavoprotein subunit beta/FixA family protein 3736207 7766030 CLM_3720 Clostridium botulinum A2 str. Kyoto electron transfer flavoprotein subunit beta/FixA family protein YP_002805803.1 3735413 R 536232 CDS YP_002805804.1 226950713 7765301 complement(3736220..3737353) 1 NC_012563.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase family protein 3737353 7765301 CLM_3721 Clostridium botulinum A2 str. Kyoto acyl-CoA dehydrogenase family protein YP_002805804.1 3736220 R 536232 CDS YP_002805805.1 226950714 7764696 complement(3737520..3738644) 1 NC_012563.1 identified by match to protein family HMM PF06050; R-phenyllactate dehydratase subunit C 3738644 fldC 7764696 fldC Clostridium botulinum A2 str. Kyoto R-phenyllactate dehydratase subunit C YP_002805805.1 3737520 R 536232 CDS YP_002805806.1 226950715 7767993 complement(3738646..3739869) 1 NC_012563.1 identified by match to protein family HMM PF06050; R-phenyllactate dehydratase subunit B 3739869 fldB 7767993 fldB Clostridium botulinum A2 str. Kyoto R-phenyllactate dehydratase subunit B YP_002805806.1 3738646 R 536232 CDS YP_002805807.1 226950716 7766415 complement(3739874..3740668) 1 NC_012563.1 identified by match to protein family HMM PF01869; match to protein family HMM TIGR00241; R-phenyllactate dehydratase activator 3740668 fldI 7766415 fldI Clostridium botulinum A2 str. Kyoto R-phenyllactate dehydratase activator YP_002805807.1 3739874 R 536232 CDS YP_002805808.1 226950717 7765695 complement(3740668..3741906) 1 NC_012563.1 identified by match to protein family HMM PF02515; E-cinnamoyl-CoA:R-phenyllactate CoA transferase 3741906 fldA 7765695 fldA Clostridium botulinum A2 str. Kyoto E-cinnamoyl-CoA:R-phenyllactate CoA transferase YP_002805808.1 3740668 R 536232 CDS YP_002805809.1 226950718 7765262 complement(3741960..3743591) 1 NC_012563.1 identified by match to protein family HMM PF00501; AMP-binding protein 3743591 7765262 CLM_3726 Clostridium botulinum A2 str. Kyoto AMP-binding protein YP_002805809.1 3741960 R 536232 CDS YP_002805810.1 226950719 7766383 complement(3744057..3745397) 1 NC_012563.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 3745397 7766383 CLM_3727 Clostridium botulinum A2 str. Kyoto branched-chain amino acid transport system II carrier protein YP_002805810.1 3744057 R 536232 CDS YP_002805811.1 226950720 7764237 complement(3745855..3747387) 1 NC_012563.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 3747387 guaA 7764237 guaA Clostridium botulinum A2 str. Kyoto GMP synthase YP_002805811.1 3745855 R 536232 CDS YP_002805812.1 226950721 7768102 complement(3747400..3748854) 1 NC_012563.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 3748854 guaB 7768102 guaB Clostridium botulinum A2 str. Kyoto inosine 5'-monophosphate dehydrogenase YP_002805812.1 3747400 R 536232 CDS YP_002805813.1 226950722 7766985 3749295..3750044 1 NC_012563.1 identified by match to protein family HMM PF01171; PP-loop family protein 3750044 7766985 CLM_3731 Clostridium botulinum A2 str. Kyoto PP-loop family protein YP_002805813.1 3749295 D 536232 CDS YP_002805814.1 226950723 7765856 complement(3750123..3751748) 1 NC_012563.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 3751748 groEL 7765856 groEL Clostridium botulinum A2 str. Kyoto chaperonin GroEL YP_002805814.1 3750123 R 536232 CDS YP_002805815.1 226950724 7764681 complement(3751778..3752065) 1 NC_012563.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 3752065 groES 7764681 groES Clostridium botulinum A2 str. Kyoto co-chaperonin GroES YP_002805815.1 3751778 R 536232 CDS YP_002805816.1 226950725 7766741 3752381..3753025 1 NC_012563.1 identified by match to protein family HMM PF07314; match to protein family HMM TIGR01906; integral membrane protein 3753025 7766741 CLM_3735 Clostridium botulinum A2 str. Kyoto integral membrane protein YP_002805816.1 3752381 D 536232 CDS YP_002805817.1 226950726 7765431 complement(3753020..3753754) 1 NC_012563.1 identified by match to protein family HMM PF09335; hypothetical protein 3753754 7765431 CLM_3734 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805817.1 3753020 R 536232 CDS YP_002805818.1 226950727 7766286 complement(3754207..3755700) 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF02906; [Fe] hydrogenase 3755700 7766286 CLM_3736 Clostridium botulinum A2 str. Kyoto [Fe] hydrogenase YP_002805818.1 3754207 R 536232 CDS YP_002805819.1 226950728 7768063 complement(3755873..3756790) 1 NC_012563.1 identified by match to protein family HMM PF00730; match to protein family HMM PF07934; putative 8-oxoguanine DNA glycosylase 3756790 7768063 CLM_3737 Clostridium botulinum A2 str. Kyoto putative 8-oxoguanine DNA glycosylase YP_002805819.1 3755873 R 536232 CDS YP_002805820.1 226950729 7764940 complement(3756940..3758322) 1 NC_012563.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 3758322 gltA 7764940 gltA Clostridium botulinum A2 str. Kyoto putative oxidoreductase YP_002805820.1 3756940 R 536232 CDS YP_002805821.1 226950730 7765157 complement(3758322..3759212) 1 NC_012563.1 identified by match to protein family HMM PF00175; ferredoxin-NADP(+) reductase subunit alpha 3759212 7765157 CLM_3739 Clostridium botulinum A2 str. Kyoto ferredoxin-NADP(+) reductase subunit alpha YP_002805821.1 3758322 R 536232 CDS YP_002805822.1 226950731 7766038 complement(3759442..3760074) 1 NC_012563.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 3760074 7766038 CLM_3740 Clostridium botulinum A2 str. Kyoto redox-sensing transcriptional repressor Rex YP_002805822.1 3759442 R 536232 CDS YP_002805823.1 226950732 7767162 3760274..3762196 1 NC_012563.1 identified by match to protein family HMM PF00005; putative drug resistance ABC transporter ATP-binding protein 3762196 7767162 CLM_3741 Clostridium botulinum A2 str. Kyoto putative drug resistance ABC transporter ATP-binding protein YP_002805823.1 3760274 D 536232 CDS YP_002805824.1 226950733 7764546 complement(3762537..3763301) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; LytTr family DNA-binding response regulator 3763301 7764546 CLM_3742 Clostridium botulinum A2 str. Kyoto LytTr family DNA-binding response regulator YP_002805824.1 3762537 R 536232 CDS YP_002805825.1 226950734 7766689 complement(3763302..3764936) 1 NC_012563.1 identified by match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694; sensor histidine kinase 3764936 7766689 CLM_3743 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002805825.1 3763302 R 536232 CDS YP_002805826.1 226950735 7767386 3765172..3766590 1 NC_012563.1 identified by match to protein family HMM PF02554; carbon starvation protein CstA 3766590 cstA 7767386 cstA Clostridium botulinum A2 str. Kyoto carbon starvation protein CstA YP_002805826.1 3765172 D 536232 CDS YP_002805827.1 226950736 7764315 complement(3766641..3769568) 1 NC_012563.1 identified by match to protein family HMM PF05193; match to protein family HMM PF08367; peptidase family protein 3769568 7764315 CLM_3745 Clostridium botulinum A2 str. Kyoto peptidase family protein YP_002805827.1 3766641 R 536232 CDS YP_002805828.1 226950737 7766939 complement(3770080..3773514) 1 NC_012563.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 3773514 pyc 7766939 pyc Clostridium botulinum A2 str. Kyoto pyruvate carboxylase YP_002805828.1 3770080 R 536232 CDS YP_002805829.1 226950738 7765839 complement(3773974..3774996) 1 NC_012563.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 3774996 7765839 CLM_3747 Clostridium botulinum A2 str. Kyoto putative DNA-binding/iron metalloprotein/AP endonuclease YP_002805829.1 3773974 R 536232 CDS YP_002805830.1 226950739 7764745 3775220..3775849 1 NC_012563.1 identified by match to protein family HMM PF05866; endodeoxyribonuclease RusA family protein 3775849 7764745 CLM_3748 Clostridium botulinum A2 str. Kyoto endodeoxyribonuclease RusA family protein YP_002805830.1 3775220 D 536232 CDS YP_002805831.1 226950740 7767218 3776085..3776216 1 NC_012563.1 hypothetical protein 3776216 7767218 CLM_3749 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805831.1 3776085 D 536232 CDS YP_002805832.1 226950741 7766596 complement(3776226..3777482) 1 NC_012563.1 identified by match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase 3777482 7766596 CLM_3750 Clostridium botulinum A2 str. Kyoto pyridine nucleotide-disulfide oxidoreductase YP_002805832.1 3776226 R 536232 CDS YP_002805833.1 226950742 7768201 complement(3777850..3778236) 1 NC_012563.1 hypothetical protein 3778236 7768201 CLM_3752 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805833.1 3777850 R 536232 CDS YP_002805834.1 226950743 7764438 complement(3778299..3779189) 1 NC_012563.1 hypothetical protein 3779189 7764438 CLM_3753 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805834.1 3778299 R 536232 CDS YP_002805835.1 226950744 7766856 complement(3779205..3780113) 1 NC_012563.1 identified by match to protein family HMM PF01297; manganese/zinc/iron chelate uptake ABC transporter substrate-binding protein 3780113 7766856 CLM_3754 Clostridium botulinum A2 str. Kyoto manganese/zinc/iron chelate uptake ABC transporter substrate-binding protein YP_002805835.1 3779205 R 536232 CDS YP_002805836.1 226950745 7765742 3780311..3781552 1 NC_012563.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; HDIG domain-containing protein 3781552 7765742 CLM_3755 Clostridium botulinum A2 str. Kyoto HDIG domain-containing protein YP_002805836.1 3780311 D 536232 CDS YP_002805837.1 226950746 7764836 3781690..3782148 1 NC_012563.1 identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein 3782148 7764836 CLM_3756 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805837.1 3781690 D 536232 CDS YP_002805838.1 226950747 7767695 3782145..3782858 1 NC_012563.1 identified by match to protein family HMM PF00814; glycoprotease family protein 3782858 7767695 CLM_3757 Clostridium botulinum A2 str. Kyoto glycoprotease family protein YP_002805838.1 3782145 D 536232 CDS YP_002805839.1 226950748 7765594 3782851..3783309 1 NC_012563.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575; ribosomal-protein-alanine acetyltransferase 3783309 rimI 7765594 rimI Clostridium botulinum A2 str. Kyoto ribosomal-protein-alanine acetyltransferase YP_002805839.1 3782851 D 536232 CDS YP_002805840.1 226950749 7764478 complement(3783667..3784890) 1 NC_012563.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 3784890 tyrS 7764478 tyrS Clostridium botulinum A2 str. Kyoto tyrosyl-tRNA synthetase YP_002805840.1 3783667 R 536232 CDS YP_002805841.1 226950750 7764234 complement(3785123..3785530) 1 NC_012563.1 hypothetical protein 3785530 7764234 CLM_3760 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805841.1 3785123 R 536232 CDS YP_002805842.1 226950751 7767540 complement(3785666..3786823) 1 NC_012563.1 identified by match to protein family HMM PF04326; putative ATP-binding protein 3786823 7767540 CLM_3761 Clostridium botulinum A2 str. Kyoto putative ATP-binding protein YP_002805842.1 3785666 R 536232 CDS YP_002805843.1 226950752 7767005 complement(3786971..3787534) 1 NC_012563.1 hypothetical protein 3787534 7767005 CLM_3762 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805843.1 3786971 R 536232 CDS YP_002805844.1 226950753 7765326 complement(3787615..3787776) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3787776 7765326 CLM_3763 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805844.1 3787615 R 536232 CDS YP_002805845.1 226950754 7765704 3788039..3789031 1 NC_012563.1 identified by match to protein family HMM PF01569; PAP2 family protein 3789031 7765704 CLM_3764 Clostridium botulinum A2 str. Kyoto PAP2 family protein YP_002805845.1 3788039 D 536232 CDS YP_002805846.1 226950755 7764839 complement(3789120..3790709) 1 NC_012563.1 identified by match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR00503; peptide chain release factor 3 3790709 prfC 7764839 prfC Clostridium botulinum A2 str. Kyoto peptide chain release factor 3 YP_002805846.1 3789120 R 536232 CDS YP_002805847.1 226950756 7766643 3791214..3792020 1 NC_012563.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD hydrolase 3792020 7766643 CLM_3766 Clostridium botulinum A2 str. Kyoto HAD hydrolase YP_002805847.1 3791214 D 536232 CDS YP_002805848.1 226950757 7767523 complement(3792240..3793238) 1 NC_012563.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3793238 trpS 7767523 trpS Clostridium botulinum A2 str. Kyoto tryptophanyl-tRNA synthetase YP_002805848.1 3792240 R 536232 CDS YP_002805849.1 226950758 7764817 complement(3793416..3793553) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3793553 7764817 CLM_3768 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805849.1 3793416 R 536232 CDS YP_002805850.1 226950759 7765760 complement(3793850..3794224) 1 NC_012563.1 identified by match to protein family HMM PF01880; match to protein family HMM PF06397; match to protein family HMM TIGR00319; match to protein family HMM TIGR00320; match to protein family HMM TIGR00332; superoxide reductase 3794224 7765760 CLM_3769 Clostridium botulinum A2 str. Kyoto superoxide reductase YP_002805850.1 3793850 R 536232 CDS YP_002805851.1 226950760 7767113 3794407..3794601 1 NC_012563.1 hypothetical protein 3794601 7767113 CLM_3770 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805851.1 3794407 D 536232 CDS YP_002805852.1 226950761 7766325 complement(3795028..3796470) 1 NC_012563.1 identified by match to protein family HMM PF00082; nisin leader peptide-processing serine protease NisP 3796470 7766325 CLM_3771 Clostridium botulinum A2 str. Kyoto nisin leader peptide-processing serine protease NisP YP_002805852.1 3795028 R 536232 CDS YP_002805853.1 226950762 7767168 complement(3797196..3798332) 1 NC_012563.1 hypothetical protein 3798332 7767168 CLM_3772 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805853.1 3797196 R 536232 CDS YP_002805854.1 226950763 7764680 complement(3798325..3799260) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3799260 7764680 CLM_3773 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002805854.1 3798325 R 536232 CDS YP_002805855.1 226950764 7765523 complement(3799434..3799709) 1 NC_012563.1 hypothetical protein 3799709 7765523 CLM_3774 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805855.1 3799434 R 536232 CDS YP_002805856.1 226950765 7766864 complement(3799799..3799963) 1 NC_012563.1 keratin associated protein 3799963 7766864 CLM_3775 Clostridium botulinum A2 str. Kyoto keratin associated protein YP_002805856.1 3799799 R 536232 CDS YP_002805857.1 226950766 7765720 complement(3800055..3800345) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3800345 7765720 CLM_3776 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805857.1 3800055 R 536232 CDS YP_002805858.1 226950767 7767062 complement(3800376..3802523) 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 3802523 7767062 CLM_3777 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002805858.1 3800376 R 536232 CDS YP_002805859.1 226950768 7767917 complement(3802537..3804270) 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; putative multidrug export ATP-binding/permease 3804270 7767917 CLM_3778 Clostridium botulinum A2 str. Kyoto putative multidrug export ATP-binding/permease YP_002805859.1 3802537 R 536232 CDS YP_002805860.1 226950769 7765565 complement(3805610..3814258) 1 NC_012563.1 identified by match to protein family HMM PF06165; match to protein family HMM PF06204; match to protein family HMM PF06205; cyclic beta 1-2 glucan synthetase 3814258 cgs 7765565 cgs Clostridium botulinum A2 str. Kyoto cyclic beta 1-2 glucan synthetase YP_002805860.1 3805610 R 536232 CDS YP_002805861.1 226950770 7766159 complement(3814523..3815791) 1 NC_012563.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; match to protein family HMM TIGR01048; diaminopimelate decarboxilase 3815791 lysA 7766159 lysA Clostridium botulinum A2 str. Kyoto diaminopimelate decarboxilase YP_002805861.1 3814523 R 536232 CDS YP_002805862.1 226950771 7767377 complement(3815825..3817027) 1 NC_012563.1 identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; aspartokinase II 3817027 lysC 7767377 lysC Clostridium botulinum A2 str. Kyoto aspartokinase II YP_002805862.1 3815825 R 536232 CDS YP_002805863.1 226950772 7765021 complement(3817423..3818721) 1 NC_012563.1 catalyzes the removal of amino acids from the N termini of peptides; putative aminopeptidase 2 3818721 7765021 CLM_3783 Clostridium botulinum A2 str. Kyoto putative aminopeptidase 2 YP_002805863.1 3817423 R 536232 CDS YP_002805864.1 226950773 7766116 3818870..3820048 1 NC_012563.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 3820048 7766116 CLM_3784 Clostridium botulinum A2 str. Kyoto cation efflux family protein YP_002805864.1 3818870 D 536232 CDS YP_002805865.1 226950774 7766793 3820185..3821276 1 NC_012563.1 hypothetical protein 3821276 7766793 CLM_3785 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805865.1 3820185 D 536232 CDS YP_002805866.1 226950775 7764498 complement(3821541..3823670) 1 NC_012563.1 identified by similarity to GB:ABK61386.1; hypothetical protein 3823670 7764498 CLM_3786 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805866.1 3821541 R 536232 CDS YP_002805867.1 226950776 7764949 complement(3823691..3825667) 1 NC_012563.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM PF07728; match to protein family HMM TIGR01241; ATP-dependent metalloprotease FtsH 3825667 ftsH 7764949 ftsH Clostridium botulinum A2 str. Kyoto ATP-dependent metalloprotease FtsH YP_002805867.1 3823691 R 536232 CDS YP_002805868.1 226950777 7767809 complement(3826084..3827475) 1 NC_012563.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 3827475 7767809 CLM_3788 Clostridium botulinum A2 str. Kyoto dipeptidase PepV YP_002805868.1 3826084 R 536232 CDS YP_002805869.1 226950778 7766672 complement(3827676..3829112) 1 NC_012563.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 3829112 proS 7766672 proS Clostridium botulinum A2 str. Kyoto prolyl-tRNA synthetase YP_002805869.1 3827676 R 536232 CDS YP_002805870.1 226950779 7765408 complement(3829536..3829778) 1 NC_012563.1 identified by match to protein family HMM PF01541; GIY-YIG domain-containing protein 3829778 7765408 CLM_3790 Clostridium botulinum A2 str. Kyoto GIY-YIG domain-containing protein YP_002805870.1 3829536 R 536232 CDS YP_002805871.1 226950780 7767816 complement(3829899..3831122) 1 NC_012563.1 hypothetical protein 3831122 7767816 CLM_3791 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805871.1 3829899 R 536232 CDS YP_002805872.1 226950781 7767397 complement(3831218..3832096) 1 NC_012563.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3832096 7767397 CLM_3792 Clostridium botulinum A2 str. Kyoto ABC transporter ATP-binding protein YP_002805872.1 3831218 R 536232 CDS YP_002805873.1 226950782 7766559 complement(3832254..3833060) 1 NC_012563.1 hypothetical protein 3833060 7766559 CLM_3793 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805873.1 3832254 R 536232 CDS YP_002805874.1 226950783 7765064 complement(3833035..3833607) 1 NC_012563.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF04967; match to protein family HMM PF08281; match to protein family HMM TIGR02937; sigma-70 family RNA polymerase sigma factor 3833607 7765064 CLM_3794 Clostridium botulinum A2 str. Kyoto sigma-70 family RNA polymerase sigma factor YP_002805874.1 3833035 R 536232 CDS YP_002805875.1 226950784 7767389 complement(3833992..3835650) 1 NC_012563.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM PF01740; match to protein family HMM TIGR00815; sulfate permease, SulP family 3835650 7767389 CLM_3795 Clostridium botulinum A2 str. Kyoto sulfate permease, SulP family YP_002805875.1 3833992 R 536232 CDS YP_002805876.1 226950785 7766822 complement(3835864..3837210) 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 3837210 7766822 CLM_3796 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002805876.1 3835864 R 536232 CDS YP_002805877.1 226950786 7764626 complement(3837233..3837925) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 3837925 7764626 CLM_3797 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002805877.1 3837233 R 536232 CDS YP_002805878.1 226950787 7764693 complement(3838189..3839397) 1 NC_012563.1 hypothetical protein 3839397 7764693 CLM_3798 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805878.1 3838189 R 536232 CDS YP_002805879.1 226950788 7767798 complement(3839402..3840307) 1 NC_012563.1 identified by match to protein family HMM PF00005; bacitracin ABC transporter ATP-binding protein 3840307 7767798 CLM_3799 Clostridium botulinum A2 str. Kyoto bacitracin ABC transporter ATP-binding protein YP_002805879.1 3839402 R 536232 CDS YP_002805880.1 226950789 7766953 3840665..3840868 1 NC_012563.1 hypothetical protein 3840868 7766953 CLM_3800 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805880.1 3840665 D 536232 CDS YP_002805881.1 226950790 7766053 complement(3840995..3841990) 1 NC_012563.1 hypothetical protein 3841990 7766053 CLM_3801 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805881.1 3840995 R 536232 CDS YP_002805882.1 226950791 7764669 complement(3842357..3843442) 1 NC_012563.1 identified by match to protein family HMM PF05913; hypothetical protein 3843442 7764669 CLM_3802 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805882.1 3842357 R 536232 CDS YP_002805883.1 226950792 7767281 complement(3843750..3844643) 1 NC_012563.1 identified by match to protein family HMM PF01869; BadF/BadG/BcrA/BcrD ATPase family protein 3844643 7767281 CLM_3803 Clostridium botulinum A2 str. Kyoto BadF/BadG/BcrA/BcrD ATPase family protein YP_002805883.1 3843750 R 536232 CDS YP_002805884.1 226950793 7767864 complement(3844703..3844999) 1 NC_012563.1 identified by match to protein family HMM PF02255; PTS system lactose/cellobiose-specific family transporter subunit IIA 3844999 7767864 CLM_3804 Clostridium botulinum A2 str. Kyoto PTS system lactose/cellobiose-specific family transporter subunit IIA YP_002805884.1 3844703 R 536232 CDS YP_002805885.1 226950794 7765538 complement(3845238..3845549) 1 NC_012563.1 identified by match to protein family HMM PF02302; PTS system lactose/cellobiose-specific family transporter subunit IIB 3845549 7765538 CLM_3805 Clostridium botulinum A2 str. Kyoto PTS system lactose/cellobiose-specific family transporter subunit IIB YP_002805885.1 3845238 R 536232 CDS YP_002805886.1 226950795 7765957 complement(3845669..3848398) 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00874; match to protein family HMM PF03610; match to protein family HMM PF07728; sigma-54 dependent transcriptional regulator 3848398 7765957 CLM_3806 Clostridium botulinum A2 str. Kyoto sigma-54 dependent transcriptional regulator YP_002805886.1 3845669 R 536232 CDS YP_002805887.1 226950796 7766832 complement(3848524..3849816) 1 NC_012563.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; PTS system lactose/cellobiose family transporter subunit IIC 3849816 7766832 CLM_3807 Clostridium botulinum A2 str. Kyoto PTS system lactose/cellobiose family transporter subunit IIC YP_002805887.1 3848524 R 536232 CDS YP_002805888.1 226950797 7768116 complement(3849897..3851234) 1 NC_012563.1 identified by match to protein family HMM PF02056; glycosyl hydrolase, family 4 3851234 7768116 CLM_3808 Clostridium botulinum A2 str. Kyoto glycosyl hydrolase, family 4 YP_002805888.1 3849897 R 536232 CDS YP_002805889.1 226950798 7765032 complement(3851587..3852900) 1 NC_012563.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; putative diguanylate cyclase 3852900 7765032 CLM_3809 Clostridium botulinum A2 str. Kyoto putative diguanylate cyclase YP_002805889.1 3851587 R 536232 CDS YP_002805890.1 226950799 7766467 3853322..3853921 1 NC_012563.1 identified by match to protein family HMM PF00589; phage integrase family site-specific recombinase 3853921 7766467 CLM_3810 Clostridium botulinum A2 str. Kyoto phage integrase family site-specific recombinase YP_002805890.1 3853322 D 536232 CDS YP_002805891.1 226950800 7764222 complement(3854232..3854582) 1 NC_012563.1 identified by match to protein family HMM PF02675; match to protein family HMM TIGR03330; S-adenosylmethionine decarboxylase 3854582 speD 7764222 speD Clostridium botulinum A2 str. Kyoto S-adenosylmethionine decarboxylase YP_002805891.1 3854232 R 536232 CDS YP_002805892.1 226950801 7765276 complement(3854642..3854758) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3854758 7765276 CLM_3812 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805892.1 3854642 R 536232 CDS YP_002805893.1 226950802 7766366 complement(3854736..3855932) 1 NC_012563.1 identified by match to protein family HMM PF01861; hypothetical protein 3855932 7766366 CLM_3813 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805893.1 3854736 R 536232 CDS YP_002805894.1 226950803 7768081 complement(3856456..3856731) 1 NC_012563.1 hypothetical protein 3856731 7768081 CLM_3814 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805894.1 3856456 R 536232 CDS YP_002805895.1 226950804 7768028 3858086..3858622 1 NC_012563.1 putative flavoredoxin 3858622 7768028 CLM_3815 Clostridium botulinum A2 str. Kyoto putative flavoredoxin YP_002805895.1 3858086 D 536232 CDS YP_002805896.1 226950805 7764719 complement(3859204..3860058) 1 NC_012563.1 identified by match to protein family HMM PF05368; hypothetical protein 3860058 7764719 CLM_3816 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805896.1 3859204 R 536232 CDS YP_002805897.1 226950806 7764807 complement(3860530..3861375) 1 NC_012563.1 identified by match to protein family HMM PF00248; aldo/keto reductase family oxidoreductase 3861375 7764807 CLM_3817 Clostridium botulinum A2 str. Kyoto aldo/keto reductase family oxidoreductase YP_002805897.1 3860530 R 536232 CDS YP_002805898.1 226950807 7767454 complement(3861399..3862025) 1 NC_012563.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358; multimeric flavodoxin WrbA family protein 3862025 7767454 CLM_3818 Clostridium botulinum A2 str. Kyoto multimeric flavodoxin WrbA family protein YP_002805898.1 3861399 R 536232 CDS YP_002805899.1 226950808 7767118 3862237..3862659 1 NC_012563.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 3862659 7767118 CLM_3819 Clostridium botulinum A2 str. Kyoto MerR family transcriptional regulator YP_002805899.1 3862237 D 536232 CDS YP_002805900.1 226950809 7765699 complement(3862932..3863336) 1 NC_012563.1 identified by match to protein family HMM PF00383; cytidine/deoxycytidylate deaminase family protein 3863336 7765699 CLM_3820 Clostridium botulinum A2 str. Kyoto cytidine/deoxycytidylate deaminase family protein YP_002805900.1 3862932 R 536232 CDS YP_002805901.1 226950810 7766724 complement(3863487..3864425) 1 NC_012563.1 identified by match to protein family HMM PF01370; NAD-dependent epimerase/dehydratase 3864425 7766724 CLM_3821 Clostridium botulinum A2 str. Kyoto NAD-dependent epimerase/dehydratase YP_002805901.1 3863487 R 536232 CDS YP_002805902.1 226950811 7766069 complement(3864479..3864886) 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 3864886 7766069 CLM_3822 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002805902.1 3864479 R 536232 CDS YP_002805903.1 226950812 7764975 complement(3864962..3865483) 1 NC_012563.1 identified by match to protein family HMM PF01872; riboflavin biosynthesis protein RibD C- domain-containing protein 3865483 7764975 CLM_3823 Clostridium botulinum A2 str. Kyoto riboflavin biosynthesis protein RibD C- domain-containing protein YP_002805903.1 3864962 R 536232 CDS YP_002805904.1 226950813 7767618 complement(3865896..3866102) 1 NC_012563.1 MarR family transcriptional regulator 3866102 7767618 CLM_3825 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002805904.1 3865896 R 536232 CDS YP_002805905.1 226950814 7766275 complement(3866240..3867184) 1 NC_012563.1 identified by match to protein family HMM PF04657; hypothetical protein 3867184 7766275 CLM_3826 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805905.1 3866240 R 536232 CDS YP_002805906.1 226950815 7765491 complement(3867429..3867830) 1 NC_012563.1 identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738; RRF2 family protein 3867830 7765491 CLM_3827 Clostridium botulinum A2 str. Kyoto RRF2 family protein YP_002805906.1 3867429 R 536232 CDS YP_002805907.1 226950816 7764638 complement(3868062..3868469) 1 NC_012563.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 3868469 7764638 CLM_3828 Clostridium botulinum A2 str. Kyoto GNAT family acetyltransferase YP_002805907.1 3868062 R 536232 CDS YP_002805908.1 226950817 7767248 complement(3868896..3870281) 1 NC_012563.1 identified by match to protein family HMM PF01938; match to protein family HMM PF02475; match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA 3870281 rumA 7767248 rumA Clostridium botulinum A2 str. Kyoto 23S rRNA (uracil-5-)-methyltransferase RumA YP_002805908.1 3868896 R 536232 CDS YP_002805909.1 226950818 7765380 complement(3870514..3870867) 1 NC_012563.1 hypothetical protein 3870867 7765380 CLM_3830 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805909.1 3870514 R 536232 CDS YP_002805910.1 226950819 7765359 complement(3870869..3870982) 1 NC_012563.1 hypothetical protein 3870982 7765359 CLM_3831 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805910.1 3870869 R 536232 CDS YP_002805911.1 226950820 7764310 3870960..3871124 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3871124 7764310 CLM_3832 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805911.1 3870960 D 536232 CDS YP_002805912.1 226950821 7767648 complement(3871194..3872204) 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00248; aldo/keto reductase family oxidoreductase 3872204 7767648 CLM_3833 Clostridium botulinum A2 str. Kyoto aldo/keto reductase family oxidoreductase YP_002805912.1 3871194 R 536232 CDS YP_002805913.1 226950822 7765822 complement(3872348..3874105) 1 NC_012563.1 identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; pyruvate kinase 3874105 pykA 7765822 pykA Clostridium botulinum A2 str. Kyoto pyruvate kinase YP_002805913.1 3872348 R 536232 CDS YP_002805914.1 226950823 7768043 complement(3874139..3875098) 1 NC_012563.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 3875098 pfkA 7768043 pfkA Clostridium botulinum A2 str. Kyoto 6-phosphofructokinase YP_002805914.1 3874139 R 536232 CDS YP_002805915.1 226950824 7767016 complement(3875340..3878897) 1 NC_012563.1 catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 3878897 dnaE 7767016 dnaE Clostridium botulinum A2 str. Kyoto DNA polymerase III DnaE YP_002805915.1 3875340 R 536232 CDS YP_002805916.1 226950825 7765769 complement(3879060..3880007) 1 NC_012563.1 identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647; hypothetical protein 3880007 7765769 CLM_3837 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805916.1 3879060 R 536232 CDS YP_002805917.1 226950826 7766424 complement(3880014..3881351) 1 NC_012563.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826; hypothetical protein 3881351 7766424 CLM_3838 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805917.1 3880014 R 536232 CDS YP_002805918.1 226950827 7767244 complement(3881348..3882232) 1 NC_012563.1 identified by match to protein family HMM PF03668; hypothetical protein 3882232 7767244 CLM_3839 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805918.1 3881348 R 536232 CDS YP_002805919.1 226950828 7764619 complement(3882352..3883272) 1 NC_012563.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 3883272 murB 7764619 murB Clostridium botulinum A2 str. Kyoto UDP-N-acetylenolpyruvoylglucosamine reductase YP_002805919.1 3882352 R 536232 CDS YP_002805920.1 226950829 7764452 complement(3883341..3884072) 1 NC_012563.1 identified by match to protein family HMM PF02811; putative hydrolase 3884072 7764452 CLM_3841 Clostridium botulinum A2 str. Kyoto putative hydrolase YP_002805920.1 3883341 R 536232 CDS YP_002805921.1 226950830 7765596 complement(3884121..3885977) 1 NC_012563.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 3885977 uvrC 7765596 uvrC Clostridium botulinum A2 str. Kyoto excinuclease ABC subunit C YP_002805921.1 3884121 R 536232 CDS YP_002805922.1 226950831 7768108 complement(3885991..3886599) 1 NC_012563.1 identified by match to protein family HMM PF04307; putative metal-dependent hydrolase, membrane-bound 3886599 7768108 CLM_3843 Clostridium botulinum A2 str. Kyoto putative metal-dependent hydrolase, membrane-bound YP_002805922.1 3885991 R 536232 CDS YP_002805923.1 226950832 7765054 complement(3886786..3887682) 1 NC_012563.1 identified by match to protein family HMM PF01336; match to protein family HMM PF01966; HD domain-containing protein 3887682 7765054 CLM_3844 Clostridium botulinum A2 str. Kyoto HD domain-containing protein YP_002805923.1 3886786 R 536232 CDS YP_002805924.1 226950833 7766663 complement(3887710..3889140) 1 NC_012563.1 identified by match to protein family HMM PF00905; penicillin-binding protein 3889140 7766663 CLM_3845 Clostridium botulinum A2 str. Kyoto penicillin-binding protein YP_002805924.1 3887710 R 536232 CDS YP_002805925.1 226950834 7767417 complement(3889145..3890374) 1 NC_012563.1 identified by match to protein family HMM PF01098; cell cycle protein, FtsW/RodA/SpoVE family 3890374 7767417 CLM_3846 Clostridium botulinum A2 str. Kyoto cell cycle protein, FtsW/RodA/SpoVE family YP_002805925.1 3889145 R 536232 CDS YP_002805926.1 226950835 7765004 complement(3890385..3890822) 1 NC_012563.1 identified by match to protein family HMM PF00498; FHA domain-containing protein 3890822 7765004 CLM_3847 Clostridium botulinum A2 str. Kyoto FHA domain-containing protein YP_002805926.1 3890385 R 536232 CDS YP_002805927.1 226950836 7767632 complement(3890921..3893743) 1 NC_012563.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 3893743 uvrA 7767632 uvrA Clostridium botulinum A2 str. Kyoto excinuclease ABC subunit A YP_002805927.1 3890921 R 536232 CDS YP_002805928.1 226950837 7766728 complement(3893762..3895750) 1 NC_012563.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 3895750 uvrB 7766728 uvrB Clostridium botulinum A2 str. Kyoto excinuclease ABC subunit B YP_002805928.1 3893762 R 536232 CDS YP_002805929.1 226950838 7766101 complement(3895752..3897047) 1 NC_012563.1 hypothetical protein 3897047 7766101 CLM_3850 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805929.1 3895752 R 536232 CDS YP_002805930.1 226950839 7765252 complement(3897136..3898341) 1 NC_012563.1 identified by match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; carboxyl-terminal protease 3898341 7765252 CLM_3851 Clostridium botulinum A2 str. Kyoto carboxyl-terminal protease YP_002805930.1 3897136 R 536232 CDS YP_002805931.1 226950840 7767899 complement(3898551..3899441) 1 NC_012563.1 identified by match to protein family HMM PF02687; putative cell division protein FtsX 3899441 7767899 CLM_3852 Clostridium botulinum A2 str. Kyoto putative cell division protein FtsX YP_002805931.1 3898551 R 536232 CDS YP_002805932.1 226950841 7767051 complement(3899431..3900117) 1 NC_012563.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02673; putative cell division ATP-binding protein FtsE 3900117 7767051 CLM_3853 Clostridium botulinum A2 str. Kyoto putative cell division ATP-binding protein FtsE YP_002805932.1 3899431 R 536232 CDS YP_002805933.1 226950842 7766528 complement(3900273..3901175) 1 NC_012563.1 identified by match to protein family HMM PF02588; hypothetical protein 3901175 7766528 CLM_3854 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805933.1 3900273 R 536232 CDS YP_002805934.1 226950843 7765848 complement(3901268..3901477) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 3901477 7765848 CLM_3855 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805934.1 3901268 R 536232 CDS YP_002805935.1 226950844 7764205 complement(3901691..3902632) 1 NC_012563.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; transketolase, pyridine binding subunit 3902632 7764205 CLM_3856 Clostridium botulinum A2 str. Kyoto transketolase, pyridine binding subunit YP_002805935.1 3901691 R 536232 CDS YP_002805936.1 226950845 7765887 complement(3902632..3903456) 1 NC_012563.1 identified by match to protein family HMM PF00456; transketolase, thiamine diphosphate binding subunit 3903456 7765887 CLM_3857 Clostridium botulinum A2 str. Kyoto transketolase, thiamine diphosphate binding subunit YP_002805936.1 3902632 R 536232 CDS YP_002805937.1 226950846 7766336 complement(3903719..3904072) 1 NC_012563.1 identified by match to protein family HMM PF02452; PemK family protein 3904072 7766336 CLM_3858 Clostridium botulinum A2 str. Kyoto PemK family protein YP_002805937.1 3903719 R 536232 CDS YP_002805938.1 226950847 7767216 complement(3904029..3904352) 1 NC_012563.1 hypothetical protein 3904352 7767216 CLM_3859 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805938.1 3904029 R 536232 CDS YP_002805939.1 226950848 7765417 complement(3904491..3905651) 1 NC_012563.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 3905651 alr 7765417 alr Clostridium botulinum A2 str. Kyoto alanine racemase YP_002805939.1 3904491 R 536232 CDS YP_002805940.1 226950849 7764781 complement(3905679..3906293) 1 NC_012563.1 hypothetical protein 3906293 7764781 CLM_3861 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805940.1 3905679 R 536232 CDS YP_002805941.1 226950850 7767198 complement(3906493..3907995) 1 NC_012563.1 identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197; carbohydrate kinase family protein 3907995 7767198 CLM_3862 Clostridium botulinum A2 str. Kyoto carbohydrate kinase family protein YP_002805941.1 3906493 R 536232 CDS YP_002805942.1 226950851 7766586 complement(3907992..3908372) 1 NC_012563.1 identified by match to protein family HMM PF01648; match to protein family HMM TIGR00516; match to protein family HMM TIGR00556; holo-ACP synthase 3908372 acpS 7766586 acpS Clostridium botulinum A2 str. Kyoto holo-ACP synthase YP_002805942.1 3907992 R 536232 CDS YP_002805943.1 226950852 7764974 complement(3908487..3908849) 1 NC_012563.1 hypothetical protein 3908849 7764974 CLM_3864 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805943.1 3908487 R 536232 CDS YP_002805944.1 226950853 7764379 complement(3909243..3910568) 1 NC_012563.1 identified by match to protein family HMM PF03553; match to protein family HMM PF06808; Na+/H+ antiporter family protein 3910568 7764379 CLM_3865 Clostridium botulinum A2 str. Kyoto Na+/H+ antiporter family protein YP_002805944.1 3909243 R 536232 CDS YP_002805945.1 226950854 7766780 complement(3910873..3911730) 1 NC_012563.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00765; YihY family protein 3911730 7766780 CLM_3867 Clostridium botulinum A2 str. Kyoto YihY family protein YP_002805945.1 3910873 R 536232 CDS YP_002805946.1 226950855 7767448 complement(3911890..3912549) 1 NC_012563.1 hypothetical protein 3912549 7767448 CLM_3868 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805946.1 3911890 R 536232 CDS YP_002805947.1 226950856 7764344 complement(3912765..3913358) 1 NC_012563.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3913358 rpsD 7764344 rpsD Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S4 YP_002805947.1 3912765 R 536232 CDS YP_002805948.1 226950857 7765050 3913804..3914976 1 NC_012563.1 identified by match to protein family HMM PF00375; sodium:dicarboxylate symporter family protein 3914976 7765050 CLM_3870 Clostridium botulinum A2 str. Kyoto sodium:dicarboxylate symporter family protein YP_002805948.1 3913804 D 536232 CDS YP_002805949.1 226950858 7767041 3915304..3915786 1 NC_012563.1 hypothetical protein 3915786 7767041 CLM_3871 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805949.1 3915304 D 536232 CDS YP_002805950.1 226950859 7767892 complement(3916117..3916911) 1 NC_012563.1 identified by match to protein family HMM PF00376; match to protein family HMM PF06445; transcriptional regulator 3916911 7767892 CLM_3872 Clostridium botulinum A2 str. Kyoto transcriptional regulator YP_002805950.1 3916117 R 536232 CDS YP_002805951.1 226950860 7764768 complement(3916920..3917759) 1 NC_012563.1 identified by match to protein family HMM PF02633; creatininase family protein 3917759 7764768 CLM_3873 Clostridium botulinum A2 str. Kyoto creatininase family protein YP_002805951.1 3916920 R 536232 CDS YP_002805952.1 226950861 7765660 complement(3917961..3918464) 1 NC_012563.1 identified by match to protein family HMM PF00080; copper/zinc superoxide dismutase 3918464 sodC 7765660 sodC Clostridium botulinum A2 str. Kyoto copper/zinc superoxide dismutase YP_002805952.1 3917961 R 536232 CDS YP_002805953.1 226950862 7765328 complement(3918734..3920560) 1 NC_012563.1 identified by match to protein family HMM PF00310; match to protein family HMM PF01380; match to protein family HMM TIGR01135; glutamine-fructose-6-phosphate transaminase 3920560 glmS 7765328 glmS Clostridium botulinum A2 str. Kyoto glutamine-fructose-6-phosphate transaminase YP_002805953.1 3918734 R 536232 CDS YP_002805954.1 226950863 7766155 complement(3921163..3921840) 1 NC_012563.1 identified by match to protein family HMM PF00923; putative transaldolase 3921840 7766155 CLM_3877 Clostridium botulinum A2 str. Kyoto putative transaldolase YP_002805954.1 3921163 R 536232 CDS YP_002805955.1 226950864 7767039 complement(3921859..3922506) 1 NC_012563.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; haloacid dehalogenase 3922506 7767039 CLM_3878 Clostridium botulinum A2 str. Kyoto haloacid dehalogenase YP_002805955.1 3921859 R 536232 CDS YP_002805956.1 226950865 7764462 complement(3922530..3923315) 1 NC_012563.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 3923315 srlD 7764462 srlD Clostridium botulinum A2 str. Kyoto sorbitol-6-phosphate dehydrogenase YP_002805956.1 3922530 R 536232 CDS YP_002805957.1 226950866 7765506 complement(3923336..3923701) 1 NC_012563.1 identified by match to protein family HMM PF03829; PTS system glucitol/sorbitol-specific transporter subunit IIA 3923701 7765506 CLM_3880 Clostridium botulinum A2 str. Kyoto PTS system glucitol/sorbitol-specific transporter subunit IIA YP_002805957.1 3923336 R 536232 CDS YP_002805958.1 226950867 7767700 complement(3923917..3924921) 1 NC_012563.1 identified by match to protein family HMM PF03612; match to protein family HMM PF07663; match to protein family HMM TIGR00825; PTS system glucitol/sorbitol-specific transporter subunit IIBC 3924921 7767700 CLM_3881 Clostridium botulinum A2 str. Kyoto PTS system glucitol/sorbitol-specific transporter subunit IIBC YP_002805958.1 3923917 R 536232 CDS YP_002805959.1 226950868 7767686 complement(3924934..3925479) 1 NC_012563.1 identified by match to protein family HMM PF03608; match to protein family HMM TIGR00821; PTS system glucitol/sorbitol-specific transporter subunit IIC 3925479 7767686 CLM_3882 Clostridium botulinum A2 str. Kyoto PTS system glucitol/sorbitol-specific transporter subunit IIC YP_002805959.1 3924934 R 536232 CDS YP_002805960.1 226950869 7765056 complement(3925522..3925917) 1 NC_012563.1 identified by match to protein family HMM PF06923; glucitol operon activator protein 3925917 gutM 7765056 gutM Clostridium botulinum A2 str. Kyoto glucitol operon activator protein YP_002805960.1 3925522 R 536232 CDS YP_002805961.1 226950870 7765980 complement(3925931..3926980) 1 NC_012563.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; putative L-iditol 2-dehydrogenase 3926980 7765980 CLM_3884 Clostridium botulinum A2 str. Kyoto putative L-iditol 2-dehydrogenase YP_002805961.1 3925931 R 536232 CDS YP_002805962.1 226950871 7766391 complement(3927015..3927986) 1 NC_012563.1 identified by match to protein family HMM PF04198; putative glucitol operon regulator 3927986 7766391 CLM_3885 Clostridium botulinum A2 str. Kyoto putative glucitol operon regulator YP_002805962.1 3927015 R 536232 CDS YP_002805963.1 226950872 7766317 complement(3928342..3929691) 1 NC_012563.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3929691 glmM 7766317 glmM Clostridium botulinum A2 str. Kyoto phosphoglucosamine mutase YP_002805963.1 3928342 R 536232 CDS YP_002805964.1 226950873 7767210 complement(3929826..3930356) 1 NC_012563.1 identified by match to protein family HMM PF01558; 2-oxoacid:acceptor oxidoreductase subunit gamma 3930356 7767210 CLM_3887 Clostridium botulinum A2 str. Kyoto 2-oxoacid:acceptor oxidoreductase subunit gamma YP_002805964.1 3929826 R 536232 CDS YP_002805965.1 226950874 7765791 complement(3930358..3931107) 1 NC_012563.1 identified by match to protein family HMM PF02775; putative 2-oxoacid:acceptor oxidoreductase subunit beta 3931107 7765791 CLM_3888 Clostridium botulinum A2 str. Kyoto putative 2-oxoacid:acceptor oxidoreductase subunit beta YP_002805965.1 3930358 R 536232 CDS YP_002805966.1 226950875 7767597 complement(3931107..3932177) 1 NC_012563.1 catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; 2-ketoisovalerate ferredoxin reductase 3932177 7767597 CLM_3889 Clostridium botulinum A2 str. Kyoto 2-ketoisovalerate ferredoxin reductase YP_002805966.1 3931107 R 536232 CDS YP_002805967.1 226950876 7764314 complement(3932193..3932402) 1 NC_012563.1 identified by match to protein family HMM PF00037; putative 2-oxoacid:acceptor oxidoreductase subunit delta 3932402 7764314 CLM_3890 Clostridium botulinum A2 str. Kyoto putative 2-oxoacid:acceptor oxidoreductase subunit delta YP_002805967.1 3932193 R 536232 CDS YP_002805968.1 226950877 7765362 complement(3932504..3933166) 1 NC_012563.1 hypothetical protein 3933166 7765362 CLM_3891 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805968.1 3932504 R 536232 CDS YP_002805969.1 226950878 7766194 complement(3933429..3934499) 1 NC_012563.1 catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; butyrate kinase 3934499 buk 7766194 buk Clostridium botulinum A2 str. Kyoto butyrate kinase YP_002805969.1 3933429 R 536232 CDS YP_002805970.1 226950879 7767522 complement(3934528..3935439) 1 NC_012563.1 catalyzes the synthesis of butanoylphosphate from butanoyl-CoA and inorganic phosphate; phosphate butyryltransferase 3935439 ptb 7767522 ptb Clostridium botulinum A2 str. Kyoto phosphate butyryltransferase YP_002805970.1 3934528 R 536232 CDS YP_002805971.1 226950880 7764970 complement(3935432..3936526) 1 NC_012563.1 catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; butyrate kinase 3936526 buk 7764970 buk Clostridium botulinum A2 str. Kyoto butyrate kinase YP_002805971.1 3935432 R 536232 CDS YP_002805972.1 226950881 7765235 complement(3936627..3938225) 1 NC_012563.1 FAD-binding oxidoreductase 3938225 7765235 CLM_3895 Clostridium botulinum A2 str. Kyoto FAD-binding oxidoreductase YP_002805972.1 3936627 R 536232 CDS YP_002805973.1 226950882 7766695 complement(3938227..3939507) 1 NC_012563.1 identified by match to protein family HMM PF07949; hypothetical protein 3939507 7766695 CLM_3896 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805973.1 3938227 R 536232 CDS YP_002805974.1 226950883 7767971 complement(3939477..3940325) 1 NC_012563.1 identified by match to protein family HMM PF02457; match to protein family HMM TIGR00159; hypothetical protein 3940325 7767971 CLM_3897 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805974.1 3939477 R 536232 CDS YP_002805975.1 226950884 7767458 3940580..3941113 1 NC_012563.1 identified by match to protein family HMM PF07486; cell wall hydrolase family protein 3941113 7767458 CLM_3899 Clostridium botulinum A2 str. Kyoto cell wall hydrolase family protein YP_002805975.1 3940580 D 536232 CDS YP_002805976.1 226950885 7766021 complement(3941506..3942369) 1 NC_012563.1 identified by match to protein family HMM PF01134; match to protein family HMM PF07992; oxidoreductase, pyridine nucleotide-disulfide family 3942369 7766021 CLM_3900 Clostridium botulinum A2 str. Kyoto oxidoreductase, pyridine nucleotide-disulfide family YP_002805976.1 3941506 R 536232 CDS YP_002805977.1 226950886 7767327 complement(3942435..3942752) 1 NC_012563.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 3942752 trx 7767327 trx Clostridium botulinum A2 str. Kyoto thioredoxin YP_002805977.1 3942435 R 536232 CDS YP_002805978.1 226950887 7764282 complement(3942861..3944036) 1 NC_012563.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01975; isoaspartyl dipeptidase 3944036 iadA 7764282 iadA Clostridium botulinum A2 str. Kyoto isoaspartyl dipeptidase YP_002805978.1 3942861 R 536232 CDS YP_002805979.1 226950888 7766698 complement(3944111..3945364) 1 NC_012563.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein 3945364 7766698 CLM_3903 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805979.1 3944111 R 536232 CDS YP_002805980.1 226950889 7766034 complement(3945392..3946132) 1 NC_012563.1 putative lipoprotein 3946132 7766034 CLM_3904 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002805980.1 3945392 R 536232 CDS YP_002805981.1 226950890 7765636 complement(3946238..3947857) 1 NC_012563.1 identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase 3947857 ptsI 7765636 ptsI Clostridium botulinum A2 str. Kyoto phosphoenolpyruvate-protein phosphotransferase YP_002805981.1 3946238 R 536232 CDS YP_002805982.1 226950891 7764555 3948175..3950184 1 NC_012563.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00989; match to protein family HMM PF02954; match to protein family HMM TIGR00229; putative sensory box sigma-54 dependent transcriptional regulator 3950184 7764555 CLM_3906 Clostridium botulinum A2 str. Kyoto putative sensory box sigma-54 dependent transcriptional regulator YP_002805982.1 3948175 D 536232 CDS YP_002805983.1 226950892 7766164 complement(3950322..3951029) 1 NC_012563.1 identified by match to protein family HMM PF00515; hypothetical protein 3951029 7766164 CLM_3907 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002805983.1 3950322 R 536232 CDS YP_002805984.1 226950893 7765570 complement(3951099..3951662) 1 NC_012563.1 identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta region 3951662 7765570 CLM_3908 Clostridium botulinum A2 str. Kyoto hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta region YP_002805984.1 3951099 R 536232 CDS YP_002805985.1 226950894 7765142 complement(3951754..3952596) 1 NC_012563.1 Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; fumarate hydratase 3952596 7765142 CLM_3909 Clostridium botulinum A2 str. Kyoto fumarate hydratase YP_002805985.1 3951754 R 536232 CDS YP_002805986.1 226950895 7764960 complement(3952737..3953441) 1 NC_012563.1 identified by similarity to SP:P50864; match to protein family HMM PF01520; match to protein family HMM TIGR02883; N-acetylmuramoyl-L-alanine amidase CwlD 3953441 cwlD 7764960 cwlD Clostridium botulinum A2 str. Kyoto N-acetylmuramoyl-L-alanine amidase CwlD YP_002805986.1 3952737 R 536232 CDS YP_002805987.1 226950896 7767797 complement(3953707..3955323) 1 NC_012563.1 identified by match to protein family HMM PF01895; match to protein family HMM PF02690; match to protein family HMM TIGR00704; Na/Pi-cotransporter family protein/PhoU family protein 3955323 7767797 CLM_3911 Clostridium botulinum A2 str. Kyoto Na/Pi-cotransporter family protein/PhoU family protein YP_002805987.1 3953707 R 536232 CDS YP_002805988.1 226950897 7766739 complement(3955629..3956021) 1 NC_012563.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3956021 rpsI 7766739 rpsI Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S9 YP_002805988.1 3955629 R 536232 CDS YP_002805989.1 226950898 7765611 complement(3956047..3956484) 1 NC_012563.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3956484 rplM 7765611 rplM Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L13 YP_002805989.1 3956047 R 536232 CDS YP_002805990.1 226950899 7764474 complement(3956605..3957345) 1 NC_012563.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 3957345 truA 7764474 truA Clostridium botulinum A2 str. Kyoto tRNA pseudouridine synthase A YP_002805990.1 3956605 R 536232 CDS YP_002805991.1 226950900 7767284 complement(3957345..3958148) 1 NC_012563.1 identified by match to protein family HMM PF02361; cobalt transport permease, CbiQ family 3958148 7767284 CLM_3915 Clostridium botulinum A2 str. Kyoto cobalt transport permease, CbiQ family YP_002805991.1 3957345 R 536232 CDS YP_002805992.1 226950901 7766058 complement(3958145..3959011) 1 NC_012563.1 with CbiNQ forms the ABC transporter for cobalt import; Clostridia have two adjacent copies of this gene; cobalt transporter ATP-binding subunit 3959011 cbiO 7766058 cbiO Clostridium botulinum A2 str. Kyoto cobalt transporter ATP-binding subunit YP_002805992.1 3958145 R 536232 CDS YP_002805993.1 226950902 7764984 complement(3958996..3959844) 1 NC_012563.1 with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene; cobalt transporter ATP-binding subunit 3959844 7764984 CLM_3917 Clostridium botulinum A2 str. Kyoto cobalt transporter ATP-binding subunit YP_002805993.1 3958996 R 536232 CDS YP_002805994.1 226950903 7767704 complement(3959935..3960276) 1 NC_012563.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3960276 rplQ 7767704 rplQ Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L17 YP_002805994.1 3959935 R 536232 CDS YP_002805995.1 226950904 7766642 complement(3960320..3961267) 1 NC_012563.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3961267 rpoA 7766642 rpoA Clostridium botulinum A2 str. Kyoto DNA-directed RNA polymerase subunit alpha YP_002805995.1 3960320 R 536232 CDS YP_002805996.1 226950905 7766338 complement(3961335..3961955) 1 NC_012563.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3961955 rpsD 7766338 rpsD Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S4 YP_002805996.1 3961335 R 536232 CDS YP_002805997.1 226950906 7765360 complement(3961990..3962388) 1 NC_012563.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3962388 rpsK 7765360 rpsK Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S11 YP_002805997.1 3961990 R 536232 CDS YP_002805998.1 226950907 7764592 complement(3962406..3962777) 1 NC_012563.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3962777 rpsM 7764592 rpsM Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S13 YP_002805998.1 3962406 R 536232 CDS YP_002805999.1 226950908 7767405 complement(3962890..3963003) 1 NC_012563.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 3963003 rpmJ 7767405 rpmJ Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L36 YP_002805999.1 3962890 R 536232 CDS YP_002806000.1 226950909 7767831 complement(3963020..3963238) 1 NC_012563.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 3963238 infA 7767831 infA Clostridium botulinum A2 str. Kyoto translation initiation factor IF-1 YP_002806000.1 3963020 R 536232 CDS YP_002806001.1 226950910 7766682 complement(3963246..3963527) 1 NC_012563.1 hypothetical protein 3963527 7766682 CLM_3925 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806001.1 3963246 R 536232 CDS YP_002806002.1 226950911 7766047 complement(3963542..3964291) 1 NC_012563.1 identified by match to protein family HMM PF00557; match to protein family HMM TIGR00500; methionine aminopeptidase 3964291 map 7766047 map Clostridium botulinum A2 str. Kyoto methionine aminopeptidase YP_002806002.1 3963542 R 536232 CDS YP_002806003.1 226950912 7765015 complement(3964291..3964941) 1 NC_012563.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 3964941 adk 7765015 adk Clostridium botulinum A2 str. Kyoto adenylate kinase YP_002806003.1 3964291 R 536232 CDS YP_002806004.1 226950913 7767313 complement(3964965..3966242) 1 NC_012563.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 3966242 secY 7767313 secY Clostridium botulinum A2 str. Kyoto preprotein translocase subunit SecY YP_002806004.1 3964965 R 536232 CDS YP_002806005.1 226950914 7766263 complement(3966243..3966683) 1 NC_012563.1 late assembly protein; 50S ribosomal protein L15 3966683 rplO 7766263 rplO Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L15 YP_002806005.1 3966243 R 536232 CDS YP_002806006.1 226950915 7767242 complement(3966703..3966882) 1 NC_012563.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 3966882 rpmD 7767242 rpmD Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L30 YP_002806006.1 3966703 R 536232 CDS YP_002806007.1 226950916 7766686 complement(3966896..3967393) 1 NC_012563.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 3967393 rpsE 7766686 rpsE Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S5 YP_002806007.1 3966896 R 536232 CDS YP_002806008.1 226950917 7765595 complement(3967411..3967770) 1 NC_012563.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 3967770 rplR 7765595 rplR Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L18 YP_002806008.1 3967411 R 536232 CDS YP_002806009.1 226950918 7765389 complement(3967789..3968331) 1 NC_012563.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 3968331 rplF 7765389 rplF Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L6 YP_002806009.1 3967789 R 536232 CDS YP_002806010.1 226950919 7764413 complement(3968355..3968753) 1 NC_012563.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 3968753 rpsH 7764413 rpsH Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S8 YP_002806010.1 3968355 R 536232 CDS YP_002806011.1 226950920 7767581 complement(3968783..3968968) 1 NC_012563.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 3968968 rpsN 7767581 rpsN Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S14 YP_002806011.1 3968783 R 536232 CDS YP_002806012.1 226950921 7766455 complement(3968985..3969527) 1 NC_012563.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 3969527 rplE 7766455 rplE Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L5 YP_002806012.1 3968985 R 536232 CDS YP_002806013.1 226950922 7765776 complement(3969550..3969867) 1 NC_012563.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 3969867 rplX 7765776 rplX Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L24 YP_002806013.1 3969550 R 536232 CDS YP_002806014.1 226950923 7764753 complement(3969891..3970259) 1 NC_012563.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 3970259 rplN 7764753 rplN Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L14 YP_002806014.1 3969891 R 536232 CDS YP_002806015.1 226950924 7768128 complement(3970294..3970548) 1 NC_012563.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 3970548 rpsQ 7768128 rpsQ Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S17 YP_002806015.1 3970294 R 536232 CDS YP_002806016.1 226950925 7767326 complement(3970570..3970782) 1 NC_012563.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 3970782 rpmC 7767326 rpmC Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L29 YP_002806016.1 3970570 R 536232 CDS YP_002806017.1 226950926 7765892 complement(3970772..3971215) 1 NC_012563.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 3971215 rplP 7765892 rplP Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L16 YP_002806017.1 3970772 R 536232 CDS YP_002806018.1 226950927 7765574 complement(3971233..3971904) 1 NC_012563.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 3971904 rpsC 7765574 rpsC Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S3 YP_002806018.1 3971233 R 536232 CDS YP_002806019.1 226950928 7765637 complement(3971922..3972257) 1 NC_012563.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3972257 rplV 7765637 rplV Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L22 YP_002806019.1 3971922 R 536232 CDS YP_002806020.1 226950929 7766222 complement(3972279..3972563) 1 NC_012563.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3972563 rpsS 7766222 rpsS Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S19 YP_002806020.1 3972279 R 536232 CDS YP_002806021.1 226950930 7764716 complement(3972633..3973466) 1 NC_012563.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 3973466 rplB 7764716 rplB Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L2 YP_002806021.1 3972633 R 536232 CDS YP_002806022.1 226950931 7764531 complement(3973521..3973814) 1 NC_012563.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 3973814 rplW 7764531 rplW Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L23 YP_002806022.1 3973521 R 536232 CDS YP_002806023.1 226950932 7766992 complement(3973814..3974434) 1 NC_012563.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 3974434 rplD 7766992 rplD Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L4 YP_002806023.1 3973814 R 536232 CDS YP_002806024.1 226950933 7768101 complement(3974459..3975088) 1 NC_012563.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 3975088 rplC 7768101 rplC Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L3 YP_002806024.1 3974459 R 536232 CDS YP_002806025.1 226950934 7764299 complement(3975178..3975486) 1 NC_012563.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3975486 rpsJ 7764299 rpsJ Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S10 YP_002806025.1 3975178 R 536232 CDS YP_002806026.1 226950935 7764519 complement(3975883..3977076) 1 NC_012563.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3977076 tuf 7764519 tuf Clostridium botulinum A2 str. Kyoto elongation factor Tu YP_002806026.1 3975883 R 536232 CDS YP_002806027.1 226950936 7767852 complement(3977116..3979185) 1 NC_012563.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3979185 fusA 7767852 fusA Clostridium botulinum A2 str. Kyoto elongation factor G YP_002806027.1 3977116 R 536232 CDS YP_002806028.1 226950937 7766734 complement(3979257..3979727) 1 NC_012563.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 3979727 rpsG 7766734 rpsG Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S7 YP_002806028.1 3979257 R 536232 CDS YP_002806029.1 226950938 7765942 complement(3979888..3980265) 1 NC_012563.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 3980265 rpsL 7765942 rpsL Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S12 YP_002806029.1 3979888 R 536232 CDS YP_002806030.1 226950939 7764932 complement(3980341..3980583) 1 NC_012563.1 identified by match to protein family HMM PF01248; ribosomal protein L7Ae family protein 3980583 7764932 CLM_3954 Clostridium botulinum A2 str. Kyoto ribosomal protein L7Ae family protein YP_002806030.1 3980341 R 536232 CDS YP_002806031.1 226950940 7766293 complement(3980705..3984241) 1 NC_012563.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 3984241 rpoC 7766293 rpoC Clostridium botulinum A2 str. Kyoto DNA-directed RNA polymerase subunit beta' YP_002806031.1 3980705 R 536232 CDS YP_002806032.1 226950941 7765197 complement(3984262..3987960) 1 NC_012563.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 3987960 rpoB 7765197 rpoB Clostridium botulinum A2 str. Kyoto DNA-directed RNA polymerase subunit beta YP_002806032.1 3984262 R 536232 CDS YP_002806033.1 226950942 7764597 complement(3988235..3988606) 1 NC_012563.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 3988606 rplL 7764597 rplL Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L7/L12 YP_002806033.1 3988235 R 536232 CDS YP_002806034.1 226950943 7767854 complement(3988654..3989154) 1 NC_012563.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 3989154 rplJ 7767854 rplJ Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L10 YP_002806034.1 3988654 R 536232 CDS YP_002806035.1 226950944 7766746 complement(3989356..3990045) 1 NC_012563.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 3990045 rplA 7766746 rplA Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L1 YP_002806035.1 3989356 R 536232 CDS YP_002806036.1 226950945 7766352 complement(3990102..3990527) 1 NC_012563.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 3990527 rplK 7766352 rplK Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L11 YP_002806036.1 3990102 R 536232 CDS YP_002806037.1 226950946 7765647 complement(3990598..3991122) 1 NC_012563.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 3991122 nusG 7765647 nusG Clostridium botulinum A2 str. Kyoto transcription antitermination protein NusG YP_002806037.1 3990598 R 536232 CDS YP_002806038.1 226950947 7766246 complement(3991169..3991396) 1 NC_012563.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 3991396 secE 7766246 secE Clostridium botulinum A2 str. Kyoto preprotein translocase subunit SecE YP_002806038.1 3991169 R 536232 CDS YP_002806039.1 226950948 7767827 complement(3991446..3991595) 1 NC_012563.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 3991595 rpmG 7767827 rpmG Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L33 YP_002806039.1 3991446 R 536232 CDS YP_002806040.1 226950949 7764769 complement(3991797..3992990) 1 NC_012563.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3992990 tuf 7764769 tuf Clostridium botulinum A2 str. Kyoto elongation factor Tu YP_002806040.1 3991797 R 536232 CDS YP_002806041.1 226950950 7768232 complement(3993306..3993947) 1 NC_012563.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 3993947 sigH 7768232 sigH Clostridium botulinum A2 str. Kyoto RNA polymerase factor sigma-70 YP_002806041.1 3993306 R 536232 CDS YP_002806042.1 226950951 7766928 complement(3994021..3994530) 1 NC_012563.1 identified by match to protein family HMM PF05991; hypothetical protein 3994530 7766928 CLM_3968 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806042.1 3994021 R 536232 CDS YP_002806043.1 226950952 7764341 complement(3994533..3995306) 1 NC_012563.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; TrmH family RNA methyltransferase 3995306 7764341 CLM_3969 Clostridium botulinum A2 str. Kyoto TrmH family RNA methyltransferase YP_002806043.1 3994533 R 536232 CDS YP_002806044.1 226950953 7765178 complement(3995309..3996061) 1 NC_012563.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 3996061 thyX 7765178 thyX Clostridium botulinum A2 str. Kyoto FAD-dependent thymidylate synthase YP_002806044.1 3995309 R 536232 CDS YP_002806045.1 226950954 7764347 complement(3996051..3996491) 1 NC_012563.1 identified by match to protein family HMM PF00636; RNase3 domain-containing protein 3996491 7764347 CLM_3971 Clostridium botulinum A2 str. Kyoto RNase3 domain-containing protein YP_002806045.1 3996051 R 536232 CDS YP_002806046.1 226950955 7765556 complement(3996540..3997937) 1 NC_012563.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 3997937 cysS 7765556 cysS Clostridium botulinum A2 str. Kyoto cysteinyl-tRNA synthetase YP_002806046.1 3996540 R 536232 CDS YP_002806047.1 226950956 7766440 complement(3997966..3999183) 1 NC_012563.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01127; threonine ammonia-lyase 3999183 ilvA 7766440 ilvA Clostridium botulinum A2 str. Kyoto threonine ammonia-lyase YP_002806047.1 3997966 R 536232 CDS YP_002806048.1 226950957 7767380 complement(3999255..4000892) 1 NC_012563.1 identified by match to protein family HMM PF03129; match to protein family HMM PF04073; putative prolyl-tRNA synthetase 4000892 7767380 CLM_3974 Clostridium botulinum A2 str. Kyoto putative prolyl-tRNA synthetase YP_002806048.1 3999255 R 536232 CDS YP_002806049.1 226950958 7765382 complement(4001003..4001692) 1 NC_012563.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4001692 ispD 7765382 ispD Clostridium botulinum A2 str. Kyoto 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002806049.1 4001003 R 536232 CDS YP_002806050.1 226950959 7766491 complement(4001694..4002794) 1 NC_012563.1 identified by match to protein family HMM PF01850; match to protein family HMM PF01938; PIN/TRAM domain-containing protein 4002794 7766491 CLM_3976 Clostridium botulinum A2 str. Kyoto PIN/TRAM domain-containing protein YP_002806050.1 4001694 R 536232 CDS YP_002806051.1 226950960 7767628 4003199..4003597 1 NC_012563.1 hypothetical protein 4003597 7767628 CLM_3977 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806051.1 4003199 D 536232 CDS YP_002806052.1 226950961 7765718 complement(4003629..4004690) 1 NC_012563.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA 4004690 7765718 CLM_3978 Clostridium botulinum A2 str. Kyoto DNA integrity scanning protein DisA YP_002806052.1 4003629 R 536232 CDS YP_002806053.1 226950962 7764709 complement(4004709..4006067) 1 NC_012563.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4006067 radA 7764709 radA Clostridium botulinum A2 str. Kyoto DNA repair protein RadA YP_002806053.1 4004709 R 536232 CDS YP_002806054.1 226950963 7765871 complement(4006187..4008622) 1 NC_012563.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; negative regulator of genetic competence MecB/ClpC 4008622 clpC 7765871 clpC Clostridium botulinum A2 str. Kyoto negative regulator of genetic competence MecB/ClpC YP_002806054.1 4006187 R 536232 CDS YP_002806055.1 226950964 7767024 complement(4008624..4009667) 1 NC_012563.1 identified by match to protein family HMM PF00217; ATP:guanido phosphotransferase 4009667 7767024 CLM_3981 Clostridium botulinum A2 str. Kyoto ATP:guanido phosphotransferase YP_002806055.1 4008624 R 536232 CDS YP_002806056.1 226950965 7768092 complement(4009672..4010199) 1 NC_012563.1 identified by match to protein family HMM PF02151; UVR domain-containing protein 4010199 7768092 CLM_3982 Clostridium botulinum A2 str. Kyoto UVR domain-containing protein YP_002806056.1 4009672 R 536232 CDS YP_002806057.1 226950966 7765177 complement(4010222..4010686) 1 NC_012563.1 identified by match to protein family HMM PF05848; transciptional repressor CtsR 4010686 ctsR 7765177 ctsR Clostridium botulinum A2 str. Kyoto transciptional repressor CtsR YP_002806057.1 4010222 R 536232 CDS YP_002806058.1 226950967 7766132 complement(4011082..4011312) 1 NC_012563.1 hypothetical protein 4011312 7766132 CLM_3984 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806058.1 4011082 R 536232 CDS YP_002806059.1 226950968 7767592 complement(4011659..4013731) 1 NC_012563.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 4013731 fusA 7767592 fusA Clostridium botulinum A2 str. Kyoto elongation factor G YP_002806059.1 4011659 R 536232 CDS YP_002806060.1 226950969 7768136 4014690..4015346 1 NC_012563.1 hypothetical protein 4015346 7768136 CLM_3990 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806060.1 4014690 D 536232 CDS YP_002806061.1 226950970 7767596 4015420..4015875 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 4015875 7767596 CLM_3991 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806061.1 4015420 D 536232 CDS YP_002806062.1 226950971 7768133 4019929..4020585 1 NC_012563.1 hypothetical protein 4020585 7768133 CLM_3999 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806062.1 4019929 D 536232 CDS YP_002806063.1 226950972 7764786 4020659..4021114 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 4021114 7764786 CLM_4000 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806063.1 4020659 D 536232 CDS YP_002806064.1 226950973 7768147 complement(4024744..4026120) 1 NC_012563.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 4026120 murD 7768147 murD Clostridium botulinum A2 str. Kyoto UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002806064.1 4024744 R 536232 CDS YP_002806065.1 226950974 7766769 complement(4026946..4028337) 1 NC_012563.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 4028337 glyS 7766769 glyS Clostridium botulinum A2 str. Kyoto glycyl-tRNA synthetase YP_002806065.1 4026946 R 536232 CDS YP_002806066.1 226950975 7766084 complement(4028657..4030171) 1 NC_012563.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4030171 lysS 7766084 lysS Clostridium botulinum A2 str. Kyoto lysyl-tRNA synthetase YP_002806066.1 4028657 R 536232 CDS YP_002806067.1 226950976 7764699 complement(4030190..4030672) 1 NC_012563.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 4030672 greA 7764699 greA Clostridium botulinum A2 str. Kyoto transcription elongation factor GreA YP_002806067.1 4030190 R 536232 CDS YP_002806068.1 226950977 7765261 complement(4030803..4031630) 1 NC_012563.1 hypothetical protein 4031630 7765261 CLM_4006 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806068.1 4030803 R 536232 CDS YP_002806069.1 226950978 7764437 complement(4031680..4032651) 1 NC_012563.1 identified by match to protein family HMM PF01180; match to protein family HMM PF01207; match to protein family HMM TIGR00737; dihydrouridine synthase 4032651 7764437 CLM_4007 Clostridium botulinum A2 str. Kyoto dihydrouridine synthase YP_002806069.1 4031680 R 536232 CDS YP_002806070.1 226950979 7767531 complement(4032661..4033437) 1 NC_012563.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 4033437 coaX 7767531 coaX Clostridium botulinum A2 str. Kyoto pantothenate kinase YP_002806070.1 4032661 R 536232 CDS YP_002806071.1 226950980 7766558 complement(4033592..4035265) 1 NC_012563.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 4035265 fhs 7766558 fhs Clostridium botulinum A2 str. Kyoto formate--tetrahydrofolate ligase YP_002806071.1 4033592 R 536232 CDS YP_002806072.1 226950981 7764847 complement(4035468..4037273) 1 NC_012563.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM PF07728; match to protein family HMM TIGR01241; ATP-dependent metalloprotease FtsH 4037273 ftsH 7764847 ftsH Clostridium botulinum A2 str. Kyoto ATP-dependent metalloprotease FtsH YP_002806072.1 4035468 R 536232 CDS YP_002806073.1 226950982 7767443 complement(4037355..4037900) 1 NC_012563.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 4037900 hpt 7767443 hpt Clostridium botulinum A2 str. Kyoto hypoxanthine phosphoribosyltransferase YP_002806073.1 4037355 R 536232 CDS YP_002806074.1 226950983 7767068 complement(4037884..4039290) 1 NC_012563.1 identified by match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433; tRNA(Ile)-lysidine synthetase 4039290 tilS 7767068 tilS Clostridium botulinum A2 str. Kyoto tRNA(Ile)-lysidine synthetase YP_002806074.1 4037884 R 536232 CDS YP_002806075.1 226950984 7766318 complement(4039439..4041826) 1 NC_012563.1 identified by match to protein family HMM PF07228; match to protein family HMM TIGR02865; stage II sporulation protein E 4041826 spoIIE 7766318 spoIIE Clostridium botulinum A2 str. Kyoto stage II sporulation protein E YP_002806075.1 4039439 R 536232 CDS YP_002806076.1 226950985 7768197 complement(4042963..4043367) 1 NC_012563.1 identified by match to protein family HMM PF00575; hypothetical protein 4043367 7768197 CLM_4021 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806076.1 4042963 R 536232 CDS YP_002806077.1 226950986 7767188 complement(4043429..4043698) 1 NC_012563.1 identified by match to protein family HMM PF04977; putative cell division protein FtsL 4043698 7767188 CLM_4022 Clostridium botulinum A2 str. Kyoto putative cell division protein FtsL YP_002806077.1 4043429 R 536232 CDS YP_002806078.1 226950987 7767829 complement(4043793..4044191) 1 NC_012563.1 identified by match to protein family HMM PF09578; match to protein family HMM TIGR02893; spore cortex biosynthesis protein YabQ 4044191 7767829 CLM_4023 Clostridium botulinum A2 str. Kyoto spore cortex biosynthesis protein YabQ YP_002806078.1 4043793 R 536232 CDS YP_002806079.1 226950988 7765657 complement(4044206..4044496) 1 NC_012563.1 identified by match to protein family HMM PF07873; match to protein family HMM TIGR02892; sporulation protein YabP 4044496 yabP 7765657 yabP Clostridium botulinum A2 str. Kyoto sporulation protein YabP YP_002806079.1 4044206 R 536232 CDS YP_002806080.1 226950989 7766722 complement(4044615..4044854) 1 NC_012563.1 identified by match to protein family HMM PF01479; S4 domain-containing protein 4044854 7766722 CLM_4025 Clostridium botulinum A2 str. Kyoto S4 domain-containing protein YP_002806080.1 4044615 R 536232 CDS YP_002806081.1 226950990 7767793 complement(4044928..4045206) 1 NC_012563.1 identified by match to protein family HMM PF00216; DNA-binding protein HU 4045206 hup 7767793 hup Clostridium botulinum A2 str. Kyoto DNA-binding protein HU YP_002806081.1 4044928 R 536232 CDS YP_002806082.1 226950991 7764996 complement(4045334..4046779) 1 NC_012563.1 identified by match to protein family HMM PF00590; match to protein family HMM PF03819; match to protein family HMM TIGR00444; MazG family protein 4046779 7764996 CLM_4027 Clostridium botulinum A2 str. Kyoto MazG family protein YP_002806082.1 4045334 R 536232 CDS YP_002806083.1 226950992 7765341 complement(4046794..4048329) 1 NC_012563.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023; stage V sporulation protein B 4048329 spoVB 7765341 spoVB Clostridium botulinum A2 str. Kyoto stage V sporulation protein B YP_002806083.1 4046794 R 536232 CDS YP_002806084.1 226950993 7765561 complement(4048462..4049013) 1 NC_012563.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439; match to protein family HMM TIGR02851; stage V sporulation protein T 4049013 7765561 CLM_4029 Clostridium botulinum A2 str. Kyoto stage V sporulation protein T YP_002806084.1 4048462 R 536232 CDS YP_002806085.1 226950994 7767236 complement(4049212..4050222) 1 NC_012563.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; peptidylprolyl isomerase 4050222 prsA 7767236 prsA Clostridium botulinum A2 str. Kyoto peptidylprolyl isomerase YP_002806085.1 4049212 R 536232 CDS YP_002806086.1 226950995 7766931 complement(4050306..4053812) 1 NC_012563.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor 4053812 mfd 7766931 mfd Clostridium botulinum A2 str. Kyoto transcription-repair coupling factor YP_002806086.1 4050306 R 536232 CDS YP_002806087.1 226950996 7765801 complement(4053840..4054409) 1 NC_012563.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 4054409 pth 7765801 pth Clostridium botulinum A2 str. Kyoto peptidyl-tRNA hydrolase YP_002806087.1 4053840 R 536232 CDS YP_002806088.1 226950997 7765852 complement(4054519..4055691) 1 NC_012563.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; putative protease 4055691 7765852 CLM_4033 Clostridium botulinum A2 str. Kyoto putative protease YP_002806088.1 4054519 R 536232 CDS YP_002806089.1 226950998 7764757 complement(4055726..4057135) 1 NC_012563.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 4057135 7764757 CLM_4034 Clostridium botulinum A2 str. Kyoto sensor histidine kinase YP_002806089.1 4055726 R 536232 CDS YP_002806090.1 226950999 7766665 complement(4057136..4057822) 1 NC_012563.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 4057822 7766665 CLM_4035 Clostridium botulinum A2 str. Kyoto DNA-binding response regulator YP_002806090.1 4057136 R 536232 CDS YP_002806091.1 226951000 7765414 complement(4058002..4058961) 1 NC_012563.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 4058961 prsA 7765414 prsA Clostridium botulinum A2 str. Kyoto ribose-phosphate pyrophosphokinase YP_002806091.1 4058002 R 536232 CDS YP_002806092.1 226951001 7767292 complement(4058982..4060355) 1 NC_012563.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4060355 glmU 7767292 glmU Clostridium botulinum A2 str. Kyoto bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002806092.1 4058982 R 536232 CDS YP_002806093.1 226951002 7766345 complement(4060517..4060804) 1 NC_012563.1 stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus; regulatory protein SpoVG 4060804 spoVG 7766345 spoVG Clostridium botulinum A2 str. Kyoto regulatory protein SpoVG YP_002806093.1 4060517 R 536232 CDS YP_002806094.1 226951003 7765487 complement(4060907..4061722) 1 NC_012563.1 identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743; pur operon repressor 4061722 purR 7765487 purR Clostridium botulinum A2 str. Kyoto pur operon repressor YP_002806094.1 4060907 R 536232 CDS YP_002806095.1 226951004 7765562 4061922..4063298 1 NC_012563.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 4063298 murC 7765562 murC Clostridium botulinum A2 str. Kyoto UDP-N-acetylmuramate--L-alanine ligase YP_002806095.1 4061922 D 536232 CDS YP_002806096.1 226951005 7767651 4063363..4063671 1 NC_012563.1 hypothetical protein 4063671 7767651 CLM_4041 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806096.1 4063363 D 536232 CDS YP_002806097.1 226951006 7768186 4063916..4065265 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF02906; [Fe] hydrogenase 4065265 7768186 CLM_4043 Clostridium botulinum A2 str. Kyoto [Fe] hydrogenase YP_002806097.1 4063916 D 536232 CDS YP_002806098.1 226951007 7765996 4065351..4065995 1 NC_012563.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; haloacid dehalogenase 4065995 7765996 CLM_4044 Clostridium botulinum A2 str. Kyoto haloacid dehalogenase YP_002806098.1 4065351 D 536232 CDS YP_002806099.1 226951008 7767064 4066321..4066719 1 NC_012563.1 hypothetical protein 4066719 7767064 CLM_4045 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806099.1 4066321 D 536232 CDS YP_002806100.1 226951009 7765053 complement(4066786..4067505) 1 NC_012563.1 catalyzes the formation of (2R)-3-sulfolactate from (2R)-2-phospho-3-sulfolactate; 2-phosphosulfolactate phosphatase 4067505 7765053 CLM_4046 Clostridium botulinum A2 str. Kyoto 2-phosphosulfolactate phosphatase YP_002806100.1 4066786 R 536232 CDS YP_002806101.1 226951010 7766028 complement(4067550..4068482) 1 NC_012563.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212; radical SAM protein 4068482 7766028 CLM_4047 Clostridium botulinum A2 str. Kyoto radical SAM protein YP_002806101.1 4067550 R 536232 CDS YP_002806102.1 226951011 7765470 complement(4068550..4069686) 1 NC_012563.1 putative phage head-tail adaptor 4069686 7765470 CLM_4048 Clostridium botulinum A2 str. Kyoto putative phage head-tail adaptor YP_002806102.1 4068550 R 536232 CDS YP_002806103.1 226951012 7766223 4069825..4070871 1 NC_012563.1 hypothetical protein 4070871 7766223 CLM_4049 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806103.1 4069825 D 536232 CDS YP_002806104.1 226951013 7764564 4070904..4071800 1 NC_012563.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 4071800 7764564 CLM_4050 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002806104.1 4070904 D 536232 CDS YP_002806105.1 226951014 7765998 complement(4071943..4073739) 1 NC_012563.1 identified by match to protein family HMM PF00015; match to protein family HMM PF07700; methyl-accepting chemotaxis protein 4073739 7765998 CLM_4051 Clostridium botulinum A2 str. Kyoto methyl-accepting chemotaxis protein YP_002806105.1 4071943 R 536232 CDS YP_002806106.1 226951015 7765426 complement(4074041..4074703) 1 NC_012563.1 identified by match to protein family HMM PF01381; DNA-binding protein 4074703 7765426 CLM_4052 Clostridium botulinum A2 str. Kyoto DNA-binding protein YP_002806106.1 4074041 R 536232 CDS YP_002806107.1 226951016 7764623 complement(4074718..4075092) 1 NC_012563.1 hypothetical protein 4075092 7764623 CLM_4053 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806107.1 4074718 R 536232 CDS YP_002806108.1 226951017 7766357 complement(4075110..4075628) 1 NC_012563.1 identified by match to protein family HMM PF00160; putative cyclophilin-type peptidyl-prolyl cis-trans isomerase 4075628 7766357 CLM_4054 Clostridium botulinum A2 str. Kyoto putative cyclophilin-type peptidyl-prolyl cis-trans isomerase YP_002806108.1 4075110 R 536232 CDS YP_002806109.1 226951018 7765454 complement(4075775..4076548) 1 NC_012563.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4076548 murI 7765454 murI Clostridium botulinum A2 str. Kyoto glutamate racemase YP_002806109.1 4075775 R 536232 CDS YP_002806110.1 226951019 7764632 4076741..4078639 1 NC_012563.1 identified by match to protein family HMM PF00120; putative glutamine synthetase 4078639 7764632 CLM_4056 Clostridium botulinum A2 str. Kyoto putative glutamine synthetase YP_002806110.1 4076741 D 536232 CDS YP_002806111.1 226951020 7767517 complement(4078684..4079232) 1 NC_012563.1 hypothetical protein 4079232 7767517 CLM_4057 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806111.1 4078684 R 536232 CDS YP_002806112.1 226951021 7765747 4079627..4080880 1 NC_012563.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4080880 murA 7765747 murA Clostridium botulinum A2 str. Kyoto UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002806112.1 4079627 D 536232 CDS YP_002806113.1 226951022 7764857 4080906..4081691 1 NC_012563.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 4081691 7764857 CLM_4059 Clostridium botulinum A2 str. Kyoto metallo-beta-lactamase family protein YP_002806113.1 4080906 D 536232 CDS YP_002806114.1 226951023 7767961 4081708..4082277 1 NC_012563.1 putative lipoprotein 4082277 7767961 CLM_4060 Clostridium botulinum A2 str. Kyoto putative lipoprotein YP_002806114.1 4081708 D 536232 CDS YP_002806115.1 226951024 7766425 4082292..4082795 1 NC_012563.1 identified by match to protein family HMM PF02810; hypothetical protein 4082795 7766425 CLM_4061 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806115.1 4082292 D 536232 CDS YP_002806116.1 226951025 7765342 4082974..4083453 1 NC_012563.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 4083453 7765342 CLM_4062 Clostridium botulinum A2 str. Kyoto rRNA large subunit methyltransferase YP_002806116.1 4082974 D 536232 CDS YP_002806117.1 226951026 7766407 complement(4084410..4085636) 1 NC_012563.1 identified by match to protein family HMM PF07690; major facilitator family protein 4085636 7766407 CLM_4065 Clostridium botulinum A2 str. Kyoto major facilitator family protein YP_002806117.1 4084410 R 536232 CDS YP_002806118.1 226951027 7766010 complement(4085732..4086307) 1 NC_012563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF03358; putative NADPH-dependent FMN reductase 4086307 7766010 CLM_4066 Clostridium botulinum A2 str. Kyoto putative NADPH-dependent FMN reductase YP_002806118.1 4085732 R 536232 CDS YP_002806119.1 226951028 7764712 4086600..4087172 1 NC_012563.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4087172 7764712 CLM_4067 Clostridium botulinum A2 str. Kyoto TetR family transcriptional regulator YP_002806119.1 4086600 D 536232 CDS YP_002806120.1 226951029 7766264 4087419..4087808 1 NC_012563.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 4087808 7766264 CLM_4068 Clostridium botulinum A2 str. Kyoto AraC family transcriptional regulator YP_002806120.1 4087419 D 536232 CDS YP_002806121.1 226951030 7766978 4087829..4088704 1 NC_012563.1 identified by match to protein family HMM PF00557; match to protein family HMM PF02810; match to protein family HMM TIGR00500; methionine aminopeptidase 4088704 map 7766978 map Clostridium botulinum A2 str. Kyoto methionine aminopeptidase YP_002806121.1 4087829 D 536232 CDS YP_002806122.1 226951031 7764520 complement(4088794..4089333) 1 NC_012563.1 identified by match to protein family HMM PF00881; nitroreductase family protein 4089333 7764520 CLM_4070 Clostridium botulinum A2 str. Kyoto nitroreductase family protein YP_002806122.1 4088794 R 536232 CDS YP_002806123.1 226951032 7767741 4090034..4091530 1 NC_012563.1 hypothetical protein 4091530 7767741 CLM_4071 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806123.1 4090034 D 536232 CDS YP_002806124.1 226951033 7765739 4091523..4092359 1 NC_012563.1 identified by match to protein family HMM PF00037; match to protein family HMM PF04055; radical SAM domain-containing protein 4092359 7765739 CLM_4072 Clostridium botulinum A2 str. Kyoto radical SAM domain-containing protein YP_002806124.1 4091523 D 536232 CDS YP_002806125.1 226951034 7766545 4092775..4093026 1 NC_012563.1 hypothetical protein 4093026 7766545 CLM_4073 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806125.1 4092775 D 536232 CDS YP_002806126.1 226951035 7767507 4093029..4094075 1 NC_012563.1 catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase 4094075 7767507 CLM_4074 Clostridium botulinum A2 str. Kyoto biotin synthase YP_002806126.1 4093029 D 536232 CDS YP_002806127.1 226951036 7764411 4094076..4095452 1 NC_012563.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; in Thermotoga this enzyme has an extra C-terminal domain; thiamine biosynthesis protein ThiH 4095452 thiH 7764411 thiH Clostridium botulinum A2 str. Kyoto thiamine biosynthesis protein ThiH YP_002806127.1 4094076 D 536232 CDS YP_002806128.1 226951037 7766301 4095461..4096660 1 NC_012563.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231; GTP-binding protein 4096660 7766301 CLM_4076 Clostridium botulinum A2 str. Kyoto GTP-binding protein YP_002806128.1 4095461 D 536232 CDS YP_002806129.1 226951038 7767090 4096975..4098348 1 NC_012563.1 identified by match to protein family HMM PF00474; sodium:solute symporter family protein 4098348 7767090 CLM_4077 Clostridium botulinum A2 str. Kyoto sodium:solute symporter family protein YP_002806129.1 4096975 D 536232 CDS YP_002806130.1 226951039 7767956 4098648..4099892 1 NC_012563.1 identified by match to protein family HMM PF00534; group 1 glycosyl transferase family 4099892 7767956 CLM_4078 Clostridium botulinum A2 str. Kyoto group 1 glycosyl transferase family YP_002806130.1 4098648 D 536232 CDS YP_002806131.1 226951040 7764831 complement(4100054..4100731) 1 NC_012563.1 identified by match to protein family HMM PF02811; PHP domain-containing protein 4100731 7764831 CLM_4079 Clostridium botulinum A2 str. Kyoto PHP domain-containing protein YP_002806131.1 4100054 R 536232 CDS YP_002806132.1 226951041 7766845 4101027..4101512 1 NC_012563.1 identified by match to protein family HMM PF08761; hypothetical protein 4101512 7766845 CLM_4080 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806132.1 4101027 D 536232 CDS YP_002806133.1 226951042 7767076 4101619..4102050 1 NC_012563.1 identified by match to protein family HMM PF04657; hypothetical protein 4102050 7767076 CLM_4081 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806133.1 4101619 D 536232 CDS YP_002806134.1 226951043 7767059 4102231..4103136 1 NC_012563.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 4103136 7767059 CLM_4082 Clostridium botulinum A2 str. Kyoto LysR family transcriptional regulator YP_002806134.1 4102231 D 536232 CDS YP_002806135.1 226951044 7767928 4103224..4104420 1 NC_012563.1 identified by match to protein family HMM PF00082; subtilase family protein 4104420 7767928 CLM_4083 Clostridium botulinum A2 str. Kyoto subtilase family protein YP_002806135.1 4103224 D 536232 CDS YP_002806136.1 226951045 7764275 complement(4104456..4105337) 1 NC_012563.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 4105337 7764275 CLM_4084 Clostridium botulinum A2 str. Kyoto LysR family transcriptional regulator YP_002806136.1 4104456 R 536232 CDS YP_002806137.1 226951046 7765641 complement(4105366..4106313) 1 NC_012563.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase 4106313 7765641 CLM_4085 Clostridium botulinum A2 str. Kyoto D-isomer specific 2-hydroxyacid dehydrogenase YP_002806137.1 4105366 R 536232 CDS YP_002806138.1 226951047 7767533 complement(4106513..4107352) 1 NC_012563.1 identified by match to protein family HMM PF03255; match to protein family HMM TIGR00513; acetyl-CoA carboxylase, carboxyl transferase subunit alpha 4107352 accA 7767533 accA Clostridium botulinum A2 str. Kyoto acetyl-CoA carboxylase, carboxyl transferase subunit alpha YP_002806138.1 4106513 R 536232 CDS YP_002806139.1 226951048 7765864 complement(4107399..4108268) 1 NC_012563.1 identified by match to protein family HMM TIGR00515; acetyl-CoA carboxylase, carboxyl transferase subunit beta 4108268 accD 7765864 accD Clostridium botulinum A2 str. Kyoto acetyl-CoA carboxylase, carboxyl transferase subunit beta YP_002806139.1 4107399 R 536232 CDS YP_002806140.1 226951049 7767038 complement(4108288..4109634) 1 NC_012563.1 identified by similarity to SP:P49787; match to protein family HMM PF00289; match to protein family HMM PF01071; match to protein family HMM PF02222; match to protein family HMM PF02785; match to protein family HMM PF02786; match to protein family HMM PF08443; match to protein family HMM TIGR00514; biotin carboxylase 4109634 accC 7767038 accC Clostridium botulinum A2 str. Kyoto biotin carboxylase YP_002806140.1 4108288 R 536232 CDS YP_002806141.1 226951050 7767957 complement(4109666..4110100) 1 NC_012563.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 4110100 fabZ 7767957 fabZ Clostridium botulinum A2 str. Kyoto (3R)-hydroxymyristoyl-ACP dehydratase YP_002806141.1 4109666 R 536232 CDS YP_002806142.1 226951051 7767942 complement(4110120..4110596) 1 NC_012563.1 identified by match to protein family HMM PF00364; match to protein family HMM TIGR00531; acetyl-CoA carboxylase, biotin carboxyl carrier protein 4110596 accB 7767942 accB Clostridium botulinum A2 str. Kyoto acetyl-CoA carboxylase, biotin carboxyl carrier protein YP_002806142.1 4110120 R 536232 CDS YP_002806143.1 226951052 7767683 complement(4110600..4111838) 1 NC_012563.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 4111838 fabF 7767683 fabF Clostridium botulinum A2 str. Kyoto 3-oxoacyl-(acyl carrier protein) synthase II YP_002806143.1 4110600 R 536232 CDS YP_002806144.1 226951053 7767336 complement(4111858..4112604) 1 NC_012563.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4112604 fabG 7767336 fabG Clostridium botulinum A2 str. Kyoto 3-ketoacyl-ACP reductase YP_002806144.1 4111858 R 536232 CDS YP_002806145.1 226951054 7765133 complement(4112622..4113566) 1 NC_012563.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128; malonyl CoA-acyl carrier protein transacylase 4113566 fabD 7765133 fabD Clostridium botulinum A2 str. Kyoto malonyl CoA-acyl carrier protein transacylase YP_002806145.1 4112622 R 536232 CDS YP_002806146.1 226951055 7765605 complement(4113587..4114513) 1 NC_012563.1 identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151; 2-nitropropane dioxygenase family oxidoreductase 4114513 7765605 CLM_4094 Clostridium botulinum A2 str. Kyoto 2-nitropropane dioxygenase family oxidoreductase YP_002806146.1 4113587 R 536232 CDS YP_002806147.1 226951056 7766512 complement(4114639..4114863) 1 NC_012563.1 identified by match to protein family HMM PF00550; acyl carrier protein 4114863 acpP 7766512 acpP Clostridium botulinum A2 str. Kyoto acyl carrier protein YP_002806147.1 4114639 R 536232 CDS YP_002806148.1 226951057 7767647 complement(4114904..4115884) 1 NC_012563.1 identified by match to protein family HMM PF08541; match to protein family HMM PF08545; match to protein family HMM TIGR00747; 3-oxoacyl-ACP synthase III 4115884 fabH 7767647 fabH Clostridium botulinum A2 str. Kyoto 3-oxoacyl-ACP synthase III YP_002806148.1 4114904 R 536232 CDS YP_002806149.1 226951058 7765738 complement(4115877..4116353) 1 NC_012563.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03965; MarR family transcriptional regulator 4116353 7765738 CLM_4097 Clostridium botulinum A2 str. Kyoto MarR family transcriptional regulator YP_002806149.1 4115877 R 536232 CDS YP_002806150.1 226951059 7766919 complement(4116369..4117427) 1 NC_012563.1 identified by match to protein family HMM PF03060; 2-nitropropane dioxygenase family oxidoreductase 4117427 7766919 CLM_4098 Clostridium botulinum A2 str. Kyoto 2-nitropropane dioxygenase family oxidoreductase YP_002806150.1 4116369 R 536232 CDS YP_002806151.1 226951060 7768052 complement(4117525..4118460) 1 NC_012563.1 identified by match to protein family HMM PF01551; putative peptidase 4118460 7768052 CLM_4099 Clostridium botulinum A2 str. Kyoto putative peptidase YP_002806151.1 4117525 R 536232 CDS YP_002806152.1 226951061 7766935 4118641..4119627 1 NC_012563.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446; putative DNA replication protein DnaD 4119627 7766935 CLM_4100 Clostridium botulinum A2 str. Kyoto putative DNA replication protein DnaD YP_002806152.1 4118641 D 536232 CDS YP_002806153.1 226951062 7766112 4119620..4120597 1 NC_012563.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 4120597 7766112 CLM_4101 Clostridium botulinum A2 str. Kyoto DNA replication protein DnaC YP_002806153.1 4119620 D 536232 CDS YP_002806154.1 226951063 7768180 complement(4121844..4122653) 1 NC_012563.1 identified by match to protein family HMM PF03618; hypothetical protein 4122653 7768180 CLM_4116 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806154.1 4121844 R 536232 CDS YP_002806155.1 226951064 7767745 complement(4122666..4123040) 1 NC_012563.1 CoA-binding protein 4123040 7767745 CLM_4117 Clostridium botulinum A2 str. Kyoto CoA-binding protein YP_002806155.1 4122666 R 536232 CDS YP_002806156.1 226951065 7764650 4123221..4124450 1 NC_012563.1 identified by match to protein family HMM PF03486; match to protein family HMM TIGR00275; pyridine nucleotide-disulfide oxidoreductase family protein 4124450 7764650 CLM_4118 Clostridium botulinum A2 str. Kyoto pyridine nucleotide-disulfide oxidoreductase family protein YP_002806156.1 4123221 D 536232 CDS YP_002806157.1 226951066 7765972 complement(4124552..4125301) 1 NC_012563.1 identified by match to protein family HMM PF01643; acyl-ACP thioesterase family protein 4125301 7765972 CLM_4119 Clostridium botulinum A2 str. Kyoto acyl-ACP thioesterase family protein YP_002806157.1 4124552 R 536232 CDS YP_002806158.1 226951067 7766861 complement(4125404..4125589) 1 NC_012563.1 hypothetical protein 4125589 7766861 CLM_4120 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806158.1 4125404 R 536232 CDS YP_002806159.1 226951068 7764355 complement(4125715..4127001) 1 NC_012563.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4127001 purA 7764355 purA Clostridium botulinum A2 str. Kyoto adenylosuccinate synthetase YP_002806159.1 4125715 R 536232 CDS YP_002806160.1 226951069 7765207 complement(4127233..4128618) 1 NC_012563.1 pyridine nucleotide-disulfide oxidoreductase family protein 4128618 7765207 CLM_4122 Clostridium botulinum A2 str. Kyoto pyridine nucleotide-disulfide oxidoreductase family protein YP_002806160.1 4127233 R 536232 CDS YP_002806161.1 226951070 7764445 complement(4128786..4129001) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 4129001 7764445 CLM_4123 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806161.1 4128786 R 536232 CDS YP_002806162.1 226951071 7765781 complement(4129194..4130915) 1 NC_012563.1 identified by match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphoglucomutase/phosphomannomutase family protein 4130915 7765781 CLM_4124 Clostridium botulinum A2 str. Kyoto phosphoglucomutase/phosphomannomutase family protein YP_002806162.1 4129194 R 536232 CDS YP_002806163.1 226951072 7764690 complement(4131157..4132494) 1 NC_012563.1 unwinds double stranded DNA; replicative DNA helicase 4132494 dnaB 7764690 dnaB Clostridium botulinum A2 str. Kyoto replicative DNA helicase YP_002806163.1 4131157 R 536232 CDS YP_002806164.1 226951073 7768122 complement(4132525..4134444) 1 NC_012563.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01078; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR02903; ATP-dependent protease 4134444 7768122 CLM_4126 Clostridium botulinum A2 str. Kyoto ATP-dependent protease YP_002806164.1 4132525 R 536232 CDS YP_002806165.1 226951074 7767202 complement(4134455..4134898) 1 NC_012563.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4134898 rplI 7767202 rplI Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L9 YP_002806165.1 4134455 R 536232 CDS YP_002806166.1 226951075 7766313 complement(4134898..4136883) 1 NC_012563.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH family protein 4136883 7766313 CLM_4128 Clostridium botulinum A2 str. Kyoto DHH family protein YP_002806166.1 4134898 R 536232 CDS YP_002806167.1 226951076 7767559 complement(4136884..4137888) 1 NC_012563.1 hypothetical protein 4137888 7767559 CLM_4129 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806167.1 4136884 R 536232 CDS YP_002806168.1 226951077 7766354 complement(4137900..4138217) 1 NC_012563.1 hypothetical protein 4138217 7766354 CLM_4130 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806168.1 4137900 R 536232 CDS YP_002806169.1 226951078 7765783 complement(4138365..4138607) 1 NC_012563.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4138607 rpsR 7765783 rpsR Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S18 YP_002806169.1 4138365 R 536232 CDS YP_002806170.1 226951079 7764668 complement(4138626..4139072) 1 NC_012563.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-strand binding protein 4139072 ssb 7764668 ssb Clostridium botulinum A2 str. Kyoto single-strand binding protein YP_002806170.1 4138626 R 536232 CDS YP_002806171.1 226951080 7768031 complement(4139088..4139372) 1 NC_012563.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4139372 rpsF 7768031 rpsF Clostridium botulinum A2 str. Kyoto 30S ribosomal protein S6 YP_002806171.1 4139088 R 536232 CDS YP_002806172.1 226951081 7766637 complement(4139478..4140626) 1 NC_012563.1 identified by match to protein family HMM PF06050; 2-hydroxyglutaryl-CoA dehydratase subunit D 4140626 7766637 CLM_4134 Clostridium botulinum A2 str. Kyoto 2-hydroxyglutaryl-CoA dehydratase subunit D YP_002806172.1 4139478 R 536232 CDS YP_002806173.1 226951082 7767893 complement(4140900..4141097) 1 NC_012563.1 identified by match to protein family HMM PF06107; hypothetical protein 4141097 7767893 CLM_4135 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806173.1 4140900 R 536232 CDS YP_002806174.1 226951083 7766697 complement(4141113..4141982) 1 NC_012563.1 identified by match to protein family HMM PF00924; mechanosensitive ion channel family protein 4141982 7766697 CLM_4136 Clostridium botulinum A2 str. Kyoto mechanosensitive ion channel family protein YP_002806174.1 4141113 R 536232 CDS YP_002806175.1 226951084 7766059 complement(4141989..4142234) 1 NC_012563.1 hypothetical protein 4142234 7766059 CLM_4137 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806175.1 4141989 R 536232 CDS YP_002806176.1 226951085 7764967 4142425..4143579 1 NC_012563.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR01977; cysteine desulfurase family protein 4143579 7764967 CLM_4138 Clostridium botulinum A2 str. Kyoto cysteine desulfurase family protein YP_002806176.1 4142425 D 536232 CDS YP_002806177.1 226951086 7766115 4143593..4144648 1 NC_012563.1 identified by match to protein family HMM PF01594; match to protein family HMM TIGR02872; sporulation integral membrane protein YtvI 4144648 ytvI 7766115 ytvI Clostridium botulinum A2 str. Kyoto sporulation integral membrane protein YtvI YP_002806177.1 4143593 D 536232 CDS YP_002806178.1 226951087 7765013 4144706..4145287 1 NC_012563.1 identified by match to protein family HMM PF06866; match to protein family HMM TIGR02841; putative sporulation protein YyaC 4145287 7765013 CLM_4140 Clostridium botulinum A2 str. Kyoto putative sporulation protein YyaC YP_002806178.1 4144706 D 536232 CDS YP_002806179.1 226951088 7767388 complement(4145289..4145534) 1 NC_012563.1 identified by glimmer; putative; hypothetical protein 4145534 7767388 CLM_4141 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806179.1 4145289 R 536232 CDS YP_002806180.1 226951089 7766554 complement(4145587..4146096) 1 NC_012563.1 hypothetical protein 4146096 7766554 CLM_4142 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806180.1 4145587 R 536232 CDS YP_002806181.1 226951090 7765630 complement(4146134..4146982) 1 NC_012563.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; stage 0 sporulation protein J 4146982 7765630 CLM_4143 Clostridium botulinum A2 str. Kyoto stage 0 sporulation protein J YP_002806181.1 4146134 R 536232 CDS YP_002806182.1 226951091 7764761 complement(4146998..4147762) 1 NC_012563.1 identified by match to protein family HMM PF01656; sporulation initiation inhibitor protein soj 4147762 soj 7764761 soj Clostridium botulinum A2 str. Kyoto sporulation initiation inhibitor protein soj YP_002806182.1 4146998 R 536232 CDS YP_002806183.1 226951092 7768082 complement(4147886..4148665) 1 NC_012563.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; parB family protein 4148665 7768082 CLM_4145 Clostridium botulinum A2 str. Kyoto parB family protein YP_002806183.1 4147886 R 536232 CDS YP_002806184.1 226951093 7765271 complement(4148765..4149484) 1 NC_012563.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4149484 gidB 7765271 gidB Clostridium botulinum A2 str. Kyoto 16S rRNA methyltransferase GidB YP_002806184.1 4148765 R 536232 CDS YP_002806185.1 226951094 7765830 complement(4149508..4151385) 1 NC_012563.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 4151385 gidA 7765830 gidA Clostridium botulinum A2 str. Kyoto tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002806185.1 4149508 R 536232 CDS YP_002806186.1 226951095 7766980 complement(4151394..4152779) 1 NC_012563.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4152779 trmE 7766980 trmE Clostridium botulinum A2 str. Kyoto tRNA modification GTPase TrmE YP_002806186.1 4151394 R 536232 CDS YP_002806187.1 226951096 7764631 complement(4152827..4153453) 1 NC_012563.1 identified by match to protein family HMM PF01424; jag protein 4153453 jag 7764631 jag Clostridium botulinum A2 str. Kyoto jag protein YP_002806187.1 4152827 R 536232 CDS YP_002806188.1 226951097 7765728 complement(4153471..4154124) 1 NC_012563.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 4154124 oxaA 7765728 oxaA Clostridium botulinum A2 str. Kyoto putative inner membrane protein translocase component YidC YP_002806188.1 4153471 R 536232 CDS YP_002806189.1 226951098 7766380 complement(4154150..4154359) 1 NC_012563.1 identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278; hypothetical protein 4154359 7766380 CLM_4151 Clostridium botulinum A2 str. Kyoto hypothetical protein YP_002806189.1 4154150 R 536232 CDS YP_002806190.1 226951099 7767420 complement(4154356..4154691) 1 NC_012563.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4154691 rnpA 7767420 rnpA Clostridium botulinum A2 str. Kyoto ribonuclease P YP_002806190.1 4154356 R 536232 CDS YP_002806191.1 226951100 7765112 complement(4154746..4154880) 1 NC_012563.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4154880 rpmH 7765112 rpmH Clostridium botulinum A2 str. Kyoto 50S ribosomal protein L34 YP_002806191.1 4154746 R 536232 CDS