-- dump date 20140619_042130 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 443906000001 SEQ_END SEQ_END NC_009478.1 27357 27357 DR NC_009478.1; contig end 27357..27357 Clavibacter michiganensis subsp. michiganensis NCPPB 382 443906000002 SEQ_END SEQ_END NC_009479.1 69989 69989 DR NC_009479.1; contig end 69989..69989 Clavibacter michiganensis subsp. michiganensis NCPPB 382 443906000003 SEQ_END SEQ_END NC_009480.1 3297891 3297891 DR NC_009480.1; contig end 3297891..3297891 Clavibacter michiganensis subsp. michiganensis NCPPB 382 YP_001220645.1 CDS pCM1_0001 NC_009478.1 1253 1462 D hypothetical protein (NP_879740.1| conserved hypothetical protein [Bordetella pertussis Tohama I]; ZP_00300166.1| COG1724: Predicted periplasmic or secreted lipoprotein [Geobacter metallireducens GS-15]).; hypothetical protein 1253..1462 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172823 YP_001220646.1 CDS pCM1_0002 NC_009478.1 1459 1857 D hypothetical protein (YP_055986.1| hypothetical protein PPA1278 [Propionibacterium acnes KPA171202]; NP_696949.1| hypothetical protein BL1802 [Bifidobacterium longum NCC2705]). weak similarity to: smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.; hypothetical protein 1459..1857 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172820 YP_001220647.1 CDS parA NC_009478.1 2059 2733 D putative partitioning protein, ATPase (NP_052567.1| plasmid partition protein homolog ParA [Corynebacterium glutamicum]; ZP_00109013.1| COG1192: ATPases involved in chromosome partitioning [Nostoc punctiforme]). pfam00991, ParA, ParA family ATPase.; Conserved hypothetical protein; putative partitioning protein, ATPase 2059..2733 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172833 YP_001220648.1 CDS parB NC_009478.1 2730 3008 D hypothetical protein, putative partitioning protein (ZP_00111179.1| hypothetical protein [Nostoc punctiforme]; NP_981997.1| partitioning protein ParB [Erwinia amylovora]).; putative partitioning protein 2730..3008 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172819 YP_001220649.1 CDS traG NC_009478.1 3088 5289 D putative membrane protein, putative coupling protein (NP_816955.1| conserved hypothetical protein [Enterococcus faecalis V583]; NP_114056.1| Mob protein [Streptococcus mutans]; AAL59680.1| conjugative coupling factor [Vibrio cholerae]). maybe involved in either mobilization or conjugation of the plasmid. weak similarity to: COG0433, Predicted ATPase [General function prediction only]; hypothetical protein 3088..5289 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172818 YP_001220650.1 CDS pCM1_0006 NC_009478.1 5637 6128 D hypothetical protein 5637..6128 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172841 YP_001220651.1 CDS pCM1_0007 NC_009478.1 6173 6400 D hypothetical protein 6173..6400 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172836 YP_001220652.1 CDS pCM1_0008 NC_009478.1 6465 6767 R hypothetical protein, putative transcriptional regulator ArsR family (NP_630544.1| putative regulatory protein [Streptomyces coelicolor A3(2)]; ZP_00271874.1| COG0640: Predicted transcriptional regulators [Ralstonia metallidurans CH34]). , smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor; hypothetical protein complement(6465..6767) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172827 YP_001220653.1 CDS pCM1_0009 NC_009478.1 7012 8259 D conserved hypothetical protein containing an ATPase domain (NP_301610.1| conserved hypothetical protein [Mycobacterium leprae TN]; ZP_00292164.1| COG0455: ATPases involved in chromosome partitioning [Thermobifida fusca]). , weak similarity to: COG0455, ATPases involved in chromosome partitioning, and COG1192, Soj, ATPases involved in chromosome partitioning.; hypothetical protein 7012..8259 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172829 YP_001220654.1 CDS pCM1_0010 NC_009478.1 8307 8693 D putative membrane protein (AAS20158.1| hypothetical protein [Arthrobacter aurescens]).; hypothetical protein 8307..8693 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172839 YP_001220655.1 CDS pCM1_0011 NC_009478.1 8702 9418 D Hypothetical protein; hypothetical protein 8702..9418 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172831 YP_001220656.1 CDS pCM1_0012 NC_009478.1 9421 10848 D putative membrane protein (NP_628307.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; NP_627714.1| putative ATP-binding protein [Streptomyces coelicolor A3(2)]; CAD47985.1| putative transfer gene complex protein-like protein [Arthrobacter nicotinovorans]). , maybe involved in conjugation or mobilization.; Hypothetical protein; hypothetical protein 9421..10848 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172821 YP_001220657.1 CDS pCM1_0013 NC_009478.1 10845 12527 D hypothetical membrane protein (AAS20155.1| membrane protein [Arthrobacter aurescens]; NP_825278.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; hypothetical protein 10845..12527 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172837 YP_001220658.1 CDS pCM1_0014 NC_009478.1 12524 14095 D putative ATP/GTP-binding protein (AAS20154.1| ATP/GTP-binding protein [Arthrobacter aurescens]; NP_628305.1| putative ATP/GTP-binding protein [Streptomyces coelicolor A3(2)]). may be involved in conjugation or mobilization. weak similarity to VirB4- ATPases (COG3451, VirB4, Type IV secretory pathway, VirB4 components [Intracellular trafficking and secretion]).; Conserved hypothetical protein; putative ATP/GTP-binding protein 12524..14095 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172842 YP_001220659.1 CDS pCM1_0015 NC_009478.1 14110 15213 D putative secreted protein (NP_824302.1| hypothetical protein SAV3126 [Streptomyces avermitilis MA- 4680]; CAD47991.1| hypothetical protein [Arthrobacter nicotinovorans]).; putative secreted protein 14110..15213 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172832 YP_001220660.1 CDS pCM1_0016 NC_009478.1 15210 15665 D hypothetical protein may be involved in conjugation or mobilization. weak similarity to: pfam05286, FINO, Fertility inhibition protein (FINO). This family consists of several bacterial fertility inhibition (FINO) proteins. The conjugative transfer of F-like plasmids is repressed by FinO, an RNA binding protein.; hypothetical protein 15210..15665 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172840 YP_001220661.1 CDS pCM1_0017 NC_009478.1 15659 16183 D putative membrane protein may be involved in conjugation or mobilization.; Hypothetical protein; hypothetical protein 15659..16183 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172838 YP_001220662.1 CDS pCM1_0018 NC_009478.1 16180 16938 D putative secreted protein (NP_939455.1| Conserved hypothetical exported protein [Corynebacterium diphtheriae NCTC 13129]; ZP_00226454.1| hypothetical protein Krad06003337 [Kineococcus radiotolerans SRS30216]). may be involved in conjugation or mobilization.; putative secreted protein 16180..16938 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172844 YP_001220663.1 CDS pCM1_0019 NC_009478.1 16921 17403 R hypothetical protein complement(16921..17403) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172830 YP_001220664.1 CDS celA NC_009478.1 17651 19891 D cellulase, endo-1,4-beta-glucanase (CAA44467.2| Cellulase [Clavibacter michiganensis]; AAK16222.1| cellulase CelA [Clavibacter michiganensis subsp. sepedonicus]; AAL83749.1| endo-beta-1,4-glucanase [Paenibacillus sp. KCTC8848P]). , known virulence factor, required for wilting of tomato. , , three domain structure: pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5). , smart00637, CBD_II, CBD_II domain., COG4305, Endoglucanase C-terminal domain/subunit and related proteins [Carbohydrate transport and metabolism]; High confidence in function and specificity; cellulase 17651..19891 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172825 YP_001220665.1 CDS pCM1_0021 NC_009478.1 20350 20664 D hypothetical protein 20350..20664 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172843 YP_001220666.1 CDS pCM1_0022 NC_009478.1 20749 21036 D hypothetical protein 20749..21036 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172835 YP_001220667.1 CDS ppaJ NC_009478.1 21052 21993 R putative extracellular serine protease (NP_298723.1| hypothetical protein XF1434 [Xylella fastidiosa 9a5c]; NP_642686.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]; ZP_00293497.1| COG3591: V8-like Glu-specific endopeptidase [Thermobifida fusca]).; putative extracellular serine protease complement(21052..21993) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172826 YP_001220668.1 CDS pCM1_0024 NC_009478.1 22677 23243 R hypothetical protein (NP_695884.1| hypothetical protein BL0701 [Bifidobacterium longum NCC2705]).; hypothetical protein complement(22677..23243) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172828 YP_001220669.1 CDS pin NC_009478.1 23240 23869 R putative recombinase/invertase (NP_052565.1| DNA recombinase homolog Pin [Corynebacterium glutamicum]; CAD48011.1| putative DNA recombinase [Arthrobacter nicotinovorans]). pfam00239, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. pfam02796, HTH_7, Helix-turn-helix domain of resolvase.; Hypothetical protein; DNA-invertase complement(23240..23869) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172834 YP_001220670.1 CDS pCM1_0026 NC_009478.1 24442 24714 R conserved hypothetical protein (ZP_00287374.1| COG5271: AAA ATPase containing von Willebrand factor type A (vWA)domain [Enterococcus faecium]; ZP_00008330.1| hypothetical protein Rsph024340 [Rhodobacter sphaeroides]).; hypothetical protein complement(24442..24714) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172822 YP_001220671.1 CDS pCM1_0027 NC_009478.1 24836 25072 D hypothetical protein 24836..25072 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172817 YP_001220672.1 CDS repA NC_009478.1 25373 26899 D hypothetical protein, putative replication protein (AAR27480.1| RepA [Leifsonia xyli subsp. cynodontis]; CAB43095.1| putative Rep protein [Mycobacterium fortuitum]).; putative replication protein 25373..26899 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172824 YP_001220673.1 CDS pCM2_0001 NC_009479.1 1 1539 D conserved hypothetical protein (NP_817941.1| gp90 [Mycobacteriophage Corndog]; AAS20140.1| ParB [Arthrobacter aurescens])., , pfam02195, ParBc, ParB-like nuclease domain.; hypothetical protein 1..1539 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172916 YP_001220674.1 CDS pCM2_0002 NC_009479.1 1701 2021 R hypothetical protein complement(1701..2021) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172915 YP_001220675.1 CDS pCM2_0003 NC_009479.1 2421 3329 D putative antirestriction protein (T43094 hypothetical protein - Lactococcus lactis plasmid pMRC01; YP_068542.1| antirestriction protein [Yersinia pseudotuberculosis IP 32953]).; Conserved hypothetical protein; hypothetical protein 2421..3329 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172914 YP_001220676.1 CDS pCM2_0004 NC_009479.1 3847 3966 D hypothetical protein (NP_787847.1| hypothetical protein TWT719 [Tropheryma whipplei str. Twist]; YP_061785.1| hypothetical protein Lxx07640 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 3847..3966 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172913 YP_001220677.1 CDS ssb NC_009479.1 4362 4739 D putative single-strand binding protein (NP_052579.1| single-strand binding protein homolog Ssb [Corynebacterium glutamicum]; NP_817551.1| gp102 [Mycobacteriophage CJW1]). pfam00436, SSB, Single-strand binding protein family.; Conserved hypothetical protein; hypothetical protein 4362..4739 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172912 YP_001220678.1 CDS pCM2_0006 NC_009479.1 4742 5263 D hypothetical protein 4742..5263 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172911 YP_001220679.1 CDS pCM2_0007 NC_009479.1 5260 6033 D conserved hypothetical protein, putative endonuclease (CAF19968.1| extracellular deoxyribonuclease [Corynebacterium glutamicum ATCC 13032]; NP_695460.1| narrowly conserved hypothetical protein [Bifidobacterium longum NCC2705]).; hypothetical protein 5260..6033 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172910 YP_001220680.1 CDS pCM2_0008 NC_009479.1 6096 7049 D hypothetical protein 6096..7049 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172909 YP_001220681.1 CDS pCM2_0009 NC_009479.1 7265 7753 D conserved hypothetical protein, putative bacteriophage protein (YP_025588.1| conserved hypothetical protein [Mycobacterium ulcerans]; NP_954805.1| putative bacteriophage-related protein [Gordonia westfalica]).; hypothetical protein 7265..7753 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172908 YP_001220682.1 CDS pCM2_0010 NC_009479.1 7774 8208 R hypothetical protein complement(7774..8208) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172907 YP_001220683.1 CDS pCM2_0011 NC_009479.1 8311 8550 D hypothetical protein 8311..8550 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172906 YP_001220684.1 CDS pCM2_0012 NC_009479.1 8547 9269 D hypothetical protein (AAV52093.1| putative TraA conjugation protein [Nocardioides sp. JS614]; AAS20188.1| TraA-like protein [Arthrobacter aurescens]).; hypothetical protein 8547..9269 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172905 YP_001220685.1 CDS traA NC_009479.1 9307 13785 D putative conjugal transfer protein (relexase/helicase) (AAS20144.1| TraA-like protein [Arthrobacter aurescens]; AAV52093.1| putative TraA conjugation protein [Nocardioides sp. JS614]).; Conserved hypothetical protein; putative conjugal transfer protein, Dtr system 9307..13785 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172904 YP_001220686.1 CDS pCM2_0014 NC_009479.1 13844 14287 R conserved hypothetical protein (AAS20152.1| hypothetical protein [Arthrobacter aurescens]; NP_825682.1| hypothetical protein SAV4505 [Streptomyces avermitilis MA-4680]).; hypothetical protein complement(13844..14287) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172903 YP_001220687.1 CDS traG NC_009479.1 14385 16043 R conjugal transfer protein (AAS20153.1| TraG-family protein [Arthrobacter aurescens]; NP_825686.1| putative traG-family protein [Streptomyces avermitilis MA-4680])., pfam02534, TRAG, TraG/TraD family. The TraG/TraD family are bacterial conjugation proteins. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome although the exact mechanism of action is unknown. These proteins contain a P-loop and walker-B site for nucleotide binding.; Conserved hypothetical protein; conjugal transfer protein complement(14385..16043) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172902 YP_001220688.1 CDS pCM2_0016 NC_009479.1 16650 17699 R conserved hypothetical protein, putative peptidoglycan lytic enzyme (NP_630954.1| putative secreted protein [Streptomyces coelicolor A3(2)]; YP_062952.1| peptidoglycan lytic protein P45 [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.; hypothetical protein complement(16650..17699) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172899 YP_001220689.1 CDS pCM2_0017 NC_009479.1 17696 18181 R hypothetical protein (AAS20160.1| hypothetical protein [Arthrobacter aurescens]).; hypothetical protein complement(17696..18181) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172898 YP_001220690.1 CDS pCM2_0018 NC_009479.1 17759 19210 D conserved hypothetical protein, putative ATPase (NP_215044.1| hypothetical protein Rv0530 [Mycobacterium tuberculosis H37Rv]; YP_117040.1| hypothetical protein nfa8310 [Nocardia farcinica IFM 10152]).; putative ATPase 17759..19210 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172897 YP_001220691.1 CDS pCM2_0021 NC_009479.1 18191 19441 R conserved hypothetical protein, putative ATPase (YP_117040.1| hypothetical protein nfa8310 [Nocardia farcinica IFM 10152]; NP_215044.1| hypothetical protein Rv0530 [Mycobacterium tuberculosis H37Rv]).; putative ATPase complement(18191..19441) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172896 YP_001220692.1 CDS pCM2_0022 NC_009479.1 19451 20956 R conserved hypothetical protein, putative ATP- binding protein (CAD47983.1| putative ATP-binding protein [Arthrobacter nicotinovorans]; ZP_00206739.1| COG0466: ATP-dependent Lon protease, bacterial type [Bifidobacterium longum DJO10A]). weak similarity to COG3451, VirB4, Type IV secretory pathway, VirB4 components [Intracellular trafficking and secretion].; putative ATP-binding protein complement(19451..20956) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172895 YP_001220693.1 CDS pCM2_0023 NC_009479.1 20956 22485 R conserved membrane protein (CAD47984.1| putative integral membrane protein [Arthrobacter nicotinovorans]; NP_696643.1| narrowly conserved hypothetical protein [Bifidobacterium longum NCC2705]).; hypothetical protein complement(20956..22485) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172894 YP_001220694.1 CDS pCM2_0024 NC_009479.1 22478 23770 R putative conjugal transfer protein (NP_954833.1| hypothetical protein [Gordonia westfalica]; CAD47985.1| putative transfer gene complex protein-like protein [Arthrobacter nicotinovorans]).; Conserved hypothetical protein; hypothetical protein complement(22478..23770) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172893 YP_001220695.1 CDS pCM2_0025 NC_009479.1 23767 24552 R putative secreted protein (CAD47986.1| hypothetical protein [Arthrobacter nicotinovorans]; YP_122034.1| hypothetical protein pnf11450 [Nocardia farcinica IFM 10152]).; Conserved hypothetical protein; putative secreted protein complement(23767..24552) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172892 YP_001220696.1 CDS pCM2_0026 NC_009479.1 24549 24899 R hypothetical membrane protein (CAD47987.1| hypothetical protein [Arthrobacter nicotinovorans]).; hypothetical protein complement(24549..24899) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172891 YP_001220697.1 CDS pCM2_0027 NC_009479.1 24899 25567 R hypothetical protein complement(24899..25567) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172890 YP_001220698.1 CDS pCM2_0028 NC_009479.1 25686 26822 R conserved secreted protein, putative hydrolase (AAS20163.1| hypothetical protein [Arthrobacter aurescens]; YP_062243.1| secreted protein [Leifsonia xyli subsp. xyli str. CTCB07]). , , pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. InterPro: Esterase/lipase/thioesterase.; Function unclear; hypothetical protein complement(25686..26822) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172889 YP_001220699.1 CDS pCM2_0029 NC_009479.1 26819 27736 R hypothetical membrane protein (CAD47995.1| hypothetical protein [Arthrobacter nicotinovorans]; YP_061884.1| hypothetical protein Lxx08840 [Leifsonia xyli subsp. xyli str. CTCB07]). weak similarity to: COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].; hypothetical protein complement(26819..27736) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172888 YP_001220700.1 CDS pCM2_0030 NC_009479.1 28284 28952 R hypothetical protein, putative DNA-binding protein (N-terminal half: NP_384377.1| hypothetical protein SMc00351 [Sinorhizobium meliloti 1021]; NP_521253.1| PUTATIVE TRANSCRIPTION REGULATOR PROTEIN [Ralstonia solanacearum GMI1000] ; C-terminal half: AAS20169.1| hypothetical protein [Arthrobacter aurescens]; CAD60534.1| Cinorf12 protein [Streptomyces cinnamoneus]). smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.; putative DNA-binding protein complement(28284..28952) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172887 YP_001220701.1 CDS pCM2_0031 NC_009479.1 29328 29624 R hypothetical protein complement(29328..29624) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172886 YP_001220702.1 CDS pCM2_0032 NC_009479.1 29687 31648 D hypothetical protein, putative helicase (CAD47997.1| hypothetical protein [Arthrobacter nicotinovorans]; YP_122052.1| hypothetical protein pnf230 [Nocardia farcinica IFM 10152]).; hypothetical protein 29687..31648 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172885 YP_001220703.1 CDS parA NC_009479.1 31937 32707 D putative ATPase, partitioning protein (AAC45808.1| putative plasmid partitioning protein; ParA [Rhodococcus erythropolis]; NP_841536.1| ParA family ATPase [Nitrosomonas europaea ATCC 19718]). pfam00991, ParA, ParA family ATPase.; Function unclear; putative ATPase, partitioning protein 31937..32707 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172884 YP_001220704.1 CDS pCM2_0034 NC_009479.1 33340 33681 R hypothetical protein complement(33340..33681) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172883 YP_001220705.1 CDS rhsA NC_009479.1 34001 37405 R conserved hypothetical protein, putative rhs- related protein (NP_733489.1| putative secreted protein [Streptomyces coelicolor A3(2)]; ZP_00300025.1| COG3209: Rhs family protein [Geobacter metallireducens GS-15]). pfam05593, RHS_repeat, RHS Repeat. RHS proteins contain extended repeat regions.; putative rhs related protein complement(34001..37405) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172882 YP_001220706.1 CDS pCM2_0036 NC_009479.1 39113 39457 R conserved hypothetical protein, ; YP_062335.1| hypothetical protein Lxx14130 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(39113..39457) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172878 YP_001220707.1 CDS pCM2_0037 NC_009479.1 39577 40263 R conserved hypothetical protein (ZP_00151041.2| COG2135: Uncharacterized conserved protein [Dechloromonas aromatica RCB]; NP_824216.1| hypothetical protein SAV3040 [Streptomyces avermitilis MA-4680]). pfam02586, DUF159, Uncharacterised ACR, COG2135.; hypothetical protein complement(39577..40263) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172877 YP_001220708.1 CDS pCM2_0038 NC_009479.1 40341 41342 D hypothetical protein (YP_120156.1| hypothetical protein nfa39440 [Nocardia farcinica IFM 10152]). weak similarities to VirB11 family proteins (ATPases).; hypothetical protein 40341..41342 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172876 YP_001220709.1 CDS pCM2_0039 NC_009479.1 41500 42351 D hypothetical protein 41500..42351 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172875 YP_001220710.1 CDS pCM2_0040 NC_009479.1 42684 43211 R hypothetical protein complement(42684..43211) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172874 YP_001220711.1 CDS pCM2_0041 NC_009479.1 43317 43886 D Hypothetical protein; hypothetical protein 43317..43886 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172873 YP_001220712.1 CDS pCM2_0042 NC_009479.1 44636 45133 D hypothetical protein 44636..45133 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172872 YP_001220713.1 CDS pCM2_0043 NC_009479.1 45301 45807 R hypothetical protein pfam07411, DUF1508, Domain of unknown function (DUF1508).; hypothetical protein complement(45301..45807) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172871 YP_001220714.1 CDS pCM2_0044 NC_009479.1 46277 46672 D hypothetical protein weak similarity to esterases; hypothetical protein 46277..46672 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172870 YP_001220715.1 CDS pCM2_0045 NC_009479.1 46761 46916 D hypothetical protein 46761..46916 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172869 YP_001220716.1 CDS pCM2_0046 NC_009479.1 46969 47142 D hypothetical protein 46969..47142 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172868 YP_001220717.1 CDS pCM2_0047 NC_009479.1 47770 48534 R hypothetical protein complement(47770..48534) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172867 YP_001220718.1 CDS pCM2_0048 NC_009479.1 48889 49074 R hypothetical protein complement(48889..49074) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172866 YP_001220719.1 CDS pCM2_0049 NC_009479.1 49749 50327 D hypothetical protein 49749..50327 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172865 YP_001220720.1 CDS pCM2_0050 NC_009479.1 50621 50809 D hypothetical protein 50621..50809 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172864 YP_001220721.1 CDS pCM2_0051 NC_009479.1 51643 51990 R hypothetical protein complement(51643..51990) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172863 YP_001220722.1 CDS phpB NC_009479.1 52086 52940 R putative extracellular serine protease (AAD09893.2| unknown [Clavibacter michiganensis subsp. michiganensis]; YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089, Trypsin, Trypsin. InterPro: Peptidase trypsin-like serine and cysteine proteases.; Conserved hypothetical protein; hypothetical protein complement(52086..52940) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172862 YP_001220723.1 CDS phpA NC_009479.1 53465 54298 D putative extracellular serine protease (AAD09893.2| unknown [Clavibacter michiganensis subsp. michiganensis]; YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089, Trypsin, Trypsin.; Hypothetical protein; putative extracellular serine protease 53465..54298 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172861 YP_001220724.1 CDS pat-1 NC_009479.1 55371 56213 D putative extracellular serine protease (YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07])., pfam00089, Trypsin, Trypsin. , , !! virulence factor !!; Conserved hypothetical protein; hypothetical protein 55371..56213 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172860 YP_001220725.1 CDS pCM2_0055 NC_009479.1 60511 61455 R hypothetical protein (BAD84024.1| hypothetical protein [Corynebacterium glutamicum]; CAE09114.1| hypothetical protein [Gordonia westfalica]; NP_688285.1| abortive infection protein AbiGII [Streptococcus agalactiae 2603V/R]).; hypothetical protein complement(60511..61455) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172859 YP_001220726.1 CDS pCM2_0056 NC_009479.1 61448 62452 R putative transcriptional regulator (NP_940396.1| hypothetical protein DIP2072 [Corynebacterium diphtheriae NCTC 13129]; CAE09113.1| hypothetical protein [Gordonia westfalica]).; Conserved hypothetical protein; putative transcriptional regulator complement(61448..62452) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172858 YP_001220727.1 CDS pCM2_0057 NC_009479.1 63216 63833 R hypothetical protein complement(63216..63833) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172857 YP_001220728.1 CDS pCM2_0058 NC_009479.1 63936 64526 R hypothetical protein (AAN24520.1| hypothetical protein BL0701 [Bifidobacterium longum NCC2705]; BAB97855.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032]).; hypothetical protein complement(63936..64526) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172856 YP_001220729.1 CDS pCM2_0059 NC_009479.1 64866 65033 D conserved hypothetical protein (CAG75796.1| conserved hypothetical protein [Erwinia carotovora subsp. atroseptica SCRI1043]; YP_107569.1| hypothetical protein BPSL0940 [Burkholderia pseudomallei K96243]).; hypothetical protein 64866..65033 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172855 YP_001220730.1 CDS pCM2_0060 NC_009479.1 65036 65257 D conserved hypothetical protein (NP_687579.1| hypothetical protein SAG0550 [Streptococcus agalactiae 2603V/R]; NP_766711.1| hypothetical protein bsr0071 [Bradyrhizobium japonicum USDA 110]).; hypothetical protein 65036..65257 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172854 YP_001220731.1 CDS pCM2_0061 NC_009479.1 66023 66310 D hypothetical protein (NP_696949.1| hypothetical protein BL1802 [Bifidobacterium longum NCC2705]).; hypothetical protein 66023..66310 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172853 YP_001220732.1 CDS pCM2_0062 NC_009479.1 66364 66549 R hypothetical protein complement(66364..66549) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172852 YP_001220733.1 CDS pCM2_0063 NC_009479.1 66598 66933 R hypothetical protein complement(66598..66933) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172851 YP_001220734.1 CDS pCM2_0064 NC_009479.1 67041 67535 D hypothetical protein 67041..67535 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172850 YP_001220735.1 CDS pCM2_0065 NC_009479.1 67655 67864 D hypothetical protein (NP_612167.1| YpkF [Corynebacterium jeikeium]).; hypothetical protein 67655..67864 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172849 YP_001220736.1 CDS pCM2_0066 NC_009479.1 67890 68732 D conserved hypothetical protein (NP_990877.1| unknown [Achromobacter denitrificans]; ZP_00038266.1| COG2184: Protein involved in cell division [Xylella fastidiosa Dixon]). pfam02661, Fic, Fic protein family. This family consists of the Fic (filamentation induced by cAMP) protein and its relatives.; Function unclear; hypothetical protein 67890..68732 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172848 YP_001220737.1 CDS pCM2_0067 NC_009479.1 68844 69233 R hypothetical protein complement(68844..69233) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172847 YP_001220738.1 CDS pCM2_0068 NC_009479.1 69233 69568 R hypothetical protein complement(69233..69568) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172846 YP_001220739.1 CDS pCM2_0069 NC_009479.1 69586 69903 R hypothetical protein complement(69586..69903) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172845 YP_001220740.1 CDS dnaA NC_009480.1 1 1434 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1..1434 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174723 YP_001220741.1 CDS dnaN NC_009480.1 1978 3129 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1978..3129 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173799 YP_001220742.1 CDS gndA1 NC_009480.1 3150 4037 D similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase 3150..4037 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174200 YP_001220743.1 CDS recF NC_009480.1 4045 5259 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4045..5259 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174954 YP_001220744.1 CDS CMM_0005 NC_009480.1 5256 5768 D conserved hypothetical protein (AAS02321.1| hypothetical protein MAP0004 [Mycobacterium avium subsp. paratuberculosis str. k10]; CAF18570.1| CONSERVED HYPOTHETICAL PROTEIN [Corynebacterium glutamicum ATCC 13032]). pfam05258, DUF721, Protein of unknown function (DUF721). This family contains several actinomycete proteins of unknown function.; hypothetical protein 5256..5768 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175237 YP_001220745.1 CDS gyrB NC_009480.1 5958 8003 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 5958..8003 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174484 YP_001220746.1 CDS gyrA NC_009480.1 8086 10773 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 8086..10773 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175389 YP_001220747.1 CDS CMM_0008 NC_009480.1 10766 11173 D conserved membrane protein (NP_825500.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00198923.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]).; Conserved hypothetical protein; putative integral membrane protein 10766..11173 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173662 YP_001220748.1 CDS CMM_0009 NC_009480.1 11620 12258 R hypothetical protein complement(11620..12258) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174870 YP_001220749.1 CDS ppiA NC_009480.1 12368 12907 D peptidyl-prolyl cis-trans isomerase B (EC 5.2.1.8) (P77949|PPIB_STRCH Peptidyl-prolyl cis-trans isomerase B (PPIase B) (Rotamase B) (Cyclophilin ScCypB) (S-cyclophilin); ZP_00226474.1| COG0652: Peptidyl-prolyl cis-trans isomerase (rotamase) -cyclophilin family [Kineococcus radiotolerans SRS30216]). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. pfam00160, Pro_isomerase, Cyclophilin type peptidyl-prolyl cis-trans isomerase.; High confidence in function and specificity; peptidyl-prolyl cis-trans isomerase 12368..12907 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173516 YP_001220750.1 CDS CMM_0011 NC_009480.1 12907 13770 D conserved membrane protein (NP_334528.1| Rhomboid family protein [Mycobacterium tuberculosis CDC1551]; NP_628043.1| putative membrane protein [Streptomyces coelicolor A3(2)]). pfam01694, Rhomboid, Rhomboid family.; Family membership; hypothetical protein 12907..13770 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174217 YP_001220751.1 CDS CMM_0012 NC_009480.1 14163 14402 R conserved membrane protein (NP_788965.1| putative membrane protein [Tropheryma whipplei TW08/27]; CAF18608.1| putative membrane protein [Corynebacterium glutamicum ATCC 13032]). pfam06781, UPF0233,Uncharacterised protein family (UPF0233).; Hypothetical protein; hypothetical protein complement(14163..14402) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174513 YP_001220752.1 CDS CMM_0013 NC_009480.1 14508 15308 D putative sortase (ZP_00226470.1| COG3764: Sortase (surface protein transpeptidase) [Kineococcus radiotolerans SRS30216]; NP_789137.1| putative membrane protein [Tropheryma whipplei TW08/27]). pfam04203,Sortase, Sortase family. The founder member of this family is S.aureus sortase, a transpeptidase that attaches surface proteins by the threonine of an LPXTG motif to the cell wall.; Family membership; putative sortase 14508..15308 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173818 YP_001220753.1 CDS pabA NC_009480.1 15466 16104 D glutamine amidotransferase class I, putative para-aminobenzoate/ anthranilate synthase glutamine amidotransferase component II [Includes: Para-aminobenzoate synthase glutamine amidotransferase component II (ADC synthase); Anthranilate synthase component II ] (ZP_00209755.1| COG0512: Anthranilate/para-aminobenzoate synthases component II [Magnetospirillum magnetotacticum]; NP_214527.1| pabA [Mycobacterium tuberculosis H37Rv]). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE AND ALSO INVOLVED IN THE SYNTHESIS OF ANTHRANILATE. pfam00117, GATase,Glutamine amidotransferase class-I. InterPro: Anthranilate synthase component II/delta crystallin; Specificity unclear; para-aminobenzoate synthetase component II 15466..16104 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173284 YP_001220754.1 CDS pknB NC_009480.1 16218 17966 R hypothetical protein complement(16218..17966) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175382 YP_001220755.1 CDS pknA NC_009480.1 18101 20008 R hypothetical protein complement(18101..20008) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173494 YP_001220756.1 CDS pbpA NC_009480.1 20005 21456 R putative penicillin-binding protein 2 (PBP-2) (ZP_00227926.1| COG0768: Cell division protein FtsI/penicillin-binding protein 2 [Kineococcus radiotolerans SRS30216]; NP_787904.1| penicillin-binding protein [Tropheryma whipplei str. Twist])., pfam00905,Transpeptidase, Penicillin binding protein transpeptidase domain.; High confidence in function and specificity; penicillin-binding protein complement(20005..21456) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173600 YP_001220757.1 CDS ftsW1 NC_009480.1 21453 22850 R putative cell division membrane protein (ZP_00227927.1| COG0772: Bacterial cell division membrane protein [Kineococcus radiotolerans SRS30216]; NP_695774.1| protein involved in cell wall formation and stabilization of the FtsZ ring during cell division [Bifidobacterium longum NCC2705]). This is a septum-peptidoglycan biosynthetic protein involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division (By similarity). pfam01098,FTSW_RODA_SPOVE, Cell cycle protein. This entry includes the following members; FtsW, RodA, SpoVE; High confidence in function and specificity; cell division membrane protein complement(21453..22850) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175504 YP_001220758.1 CDS CMM_0019 NC_009480.1 22843 24105 R putative serine/threonine protein phosphatase (ZP_00227928.1| COG0631: Serine/threonine protein phosphatase [Kineococcus radiotolerans SRS30216]; ZP_00058950.1| COG0631: Serine/threonine protein phosphatase [Thermobifida fusca]). pfam00481, PP2C,Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.; Function unclear; putative serine/threonine protein phosphatase complement(22843..24105) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174064 YP_001220759.1 CDS CMM_0020 NC_009480.1 24110 24694 R conserved hypothetical protein (NP_628032.1| putative secreted protein [Streptomyces coelicolor A3(2)]; CAB02439.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam00498, FHA, FHA domain. The FHA (Forkhead-associated) domain is a phosphopeptide binding motif.; hypothetical protein complement(24110..24694) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172947 YP_001220760.1 CDS CMM_0021 NC_009480.1 24691 25422 R conserved hypothetical protein containing C-terminal FOG:FHA domain (COG1716) (ZP_00227930.1| COG1716: FOG: FHA domain [Kineococcus radiotolerans SRS30216]; NP_695771.1| hypothetical protein with FHA domain [Bifidobacterium longum NCC2705]). pfam00498, FHA, FHA domain. The FHA (Forkhead-associated) domain is a phosphopeptide binding motif.; hypothetical protein complement(24691..25422) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172918 YP_001220761.1 CDS CMM_0022 NC_009480.1 25879 28146 D putative membrane protein (ZP_00121629.1| COG2898: Uncharacterized conserved protein [Bifidobacterium longum DJO10A]). pfam04329, DUF470, Family of unknown function (DUF470). This sequence is usually found in association with DUF471 and DUF472, and occasionally also with UPF0104 (pfam03706) in integral membrane proteins. pfam04331,DUF472, Family of unknown function (DUF472).; Function unclear; hypothetical protein 25879..28146 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175925 YP_001220762.1 CDS CMM_0023 NC_009480.1 28143 28829 D two-component system response regulator(NP_822457.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]; ZP_00058730.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Thermobifida fusca]). pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system response regulator 28143..28829 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172934 YP_001220763.1 CDS CMM_0024 NC_009480.1 28837 29955 D putative two-component system sensor kinase (NP_822456.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; NP_823166.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 28837..29955 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172963 YP_001220764.1 CDS rpmJ NC_009480.1 29995 30117 R rpmJ2; smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 complement(29995..30117) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172992 YP_001220765.1 CDS CMM_0026 NC_009480.1 30162 31235 D putative GTPase (NP_962706.1| hypothetical protein MAP3772c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00173773.1| COG0523: Putative GTPases (G3E family) [Methylobacillus flagellatus KT]). weak similarity to: pfam02492, cobW, Cobalamin synthesis protein/P47K.; Function unclear; hypothetical protein 30162..31235 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175338 YP_001220766.1 CDS recQ1 NC_009480.1 31412 33178 D ATP-dependent DNA helicase recQ (EC 3.6.1.-) (ZP_00198343.2| COG0514: Superfamily II DNA helicase [Kineococcus radiotolerans SRS30216]; ZP_00169039.2| COG0514: Superfamily II DNA helicase [Ralstonia eutropha JMP134]). InterPro: ATP-dependent DNA helicase RecQ pfam00270, DEAD, DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. pfam00271,Helicase_C, Helicase conserved C-terminal domain.; Specificity unclear; ATP-dependent DNA helicase 31412..33178 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172981 YP_001220767.1 CDS CMM_0028 NC_009480.1 33175 33420 D hypothetical protein 33175..33420 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173418 YP_001220768.1 CDS glsA NC_009480.1 33677 34654 D glutaminase (L-glutamine amidohydrolase) (ZP_00162219.2| COG2066: Glutaminase [Anabaena variabilis ATCC 29413]; ZP_00026087.1| COG2066: Glutaminase [Ralstonia metallidurans]). pfam04960, Glutaminase,Glutaminase. This family of enzymes deaminates glutamine to glutamate EC:3.5.1.2.; High confidence in function and specificity; putative glutaminase 33677..34654 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173028 YP_001220769.1 CDS CMM_0030 NC_009480.1 34674 35723 R putative hydrolase/acyltransferase (ZP_00187188.2| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Rubrobacter xylanophilus DSM 9941]; NP_295074.1| hydrolase,alpha/beta hydrolase fold family [Deinococcus radiodurans R1]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. InterPro: Alpha/beta hydrolase fold.; Function unclear; putative hydrolase/acyltransferase complement(34674..35723) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175932 YP_001220770.1 CDS CMM_0031 NC_009480.1 35841 36227 D putative transcriptional regulator, PadR family (NP_821203.1| putative transcriptional regulator PadR-like family [Streptomyces avermitilis MA-4680]; ZP_00209884.1| COG1695: Predicted transcriptional regulators [Magnetospirillum magnetotacticum]). pfam03551, PadR,Transcriptional regulator PadR-like family.; Specificity unclear; hypothetical protein 35841..36227 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174522 YP_001220771.1 CDS CMM_0032 NC_009480.1 36305 37552 D Hypothetical protein; hypothetical protein 36305..37552 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173015 YP_001220772.1 CDS CMM_0033 NC_009480.1 37569 37958 R conserved hypothetical protein (NP_627276.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00198785.1| COG2514: Predicted ring-cleavage extradiol dioxygenase [Kineococcus radiotolerans SRS30216]). pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; hypothetical protein complement(37569..37958) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173035 YP_001220773.1 CDS CMM_0034 NC_009480.1 40054 40860 D putative sugar phosphate isomerase/epimerase (ZP_00229027.1| COG1082: Sugar phosphate isomerases/epimerases [Kineococcus radiotolerans SRS30216]; NP_623524.1| Sugar phosphate isomerases/epimerases [Thermoanaerobacter tengcongensis]).; Function unclear; putative sugar phosphate isomerase/epimerase 40054..40860 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173065 YP_001220774.1 CDS CMM_0035 NC_009480.1 40857 41966 D putative dehydrogenase/oxidoreductase (ZP_00227973.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_241574.1| BH0708~unknown conserved protein [Bacillus halodurans C-125]). InterPro: Oxidoreductase C-terminal pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD.; Specificity unclear; putative dehydrogenase/oxidoreductase 40857..41966 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173049 YP_001220775.1 CDS CMM_0036 NC_009480.1 42124 43209 D LacI family transcriptional regulator 42124..43209 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173044 YP_001220776.1 CDS CMM_0037 NC_009480.1 45327 45899 R hypothetical protein (ZP_00230295.1| conserved hypothetical protein [Listeria monocytogenes str. 4b H7858]).; hypothetical protein complement(45327..45899) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174750 YP_001220777.1 CDS CMM_0038 NC_009480.1 47879 48292 R hypothetical protein complement(47879..48292) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175175 YP_001220778.1 CDS chpE NC_009480.1 48734 49567 R putative extracellular serine protease, family S1A (AAD09893.2| unknown [Clavibacter michiganensis subsp. michiganensis]; YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089, Trypsin, Trypsin.; Function unclear; serine protease complement(48734..49567) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173121 YP_001220779.1 CDS CMM_0040 NC_009480.1 49775 50104 R hypothetical protein complement(49775..50104) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173185 YP_001220780.1 CDS ppaA NC_009480.1 50376 51356 D putative extracellular serine protease (NP_779169.1| conserved hypothetical protein [Xylella fastidiosa Temecula1]; ZP_00293497.1| COG3591: V8-like Glu-specific endopeptidase [Thermobifida fusca]).; Function unclear; putative extracellular serine protease 50376..51356 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173189 YP_001220781.1 CDS ppaB1 NC_009480.1 51503 52507 R conserved hypothetical protein, putative extracelluar serine protease (NP_642686.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]; ZP_00227464.1| COG3591: V8-like Glu-specific endopeptidase [Kineococcus radiotolerans SRS30216]).; Function unclear; putative extracellular serine protease complement(51503..52507) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173735 YP_001220782.1 CDS pelA1 NC_009480.1 52708 53559 D putative pectate lyase (NP_625403.1| putative secreted lyase [Streptomyces coelicolor A3(2)]; CAB40884.1| pectate lyase [Bacillus sp. BP-23]). pfam03211, Pectate_lyase, Pectate lyase.; Function unclear; hypothetical protein 52708..53559 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174722 YP_001220783.1 CDS ppaC NC_009480.1 53883 54896 R conserved hypothetical protein, putative extracellular serine protease (NP_779169.1| conserved hypothetical protein [Xylella fastidiosa Temecula1]; ZP_00227464.1| COG3591: V8-like Glu-specific endopeptidase [Kineococcus radiotolerans SRS30216]).; Function unclear; putative extracellular serine protease complement(53883..54896) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175587 YP_001220784.1 CDS CMM_0045 NC_009480.1 57043 57396 R hypothetical protein complement(57043..57396) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173320 YP_001220785.1 CDS CMM_0046 NC_009480.1 61909 62718 D hypothetical protein, putative phage protein (CAD43910.1| hypothetical protein [Lactobacillus casei bacteriophage A2]; ZP_00230220.1| conserved hypothetical protein [Listeria monocytogenes str. 4b H7858]); hypothetical protein 61909..62718 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173352 YP_001220786.1 CDS CMM_0047 NC_009480.1 63422 63748 R hypothetical protein (weak similarity to: NP_858518.1| hypothetical protein [Rhodococcus equi]; YP_056012.1| hypothetical protein PPA1305 [Propionibacterium acnes KPA171202]).; hypothetical protein complement(63422..63748) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173152 YP_001220787.1 CDS CMM_0048 NC_009480.1 64558 64995 R hypothetical protein complement(64558..64995) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173172 YP_001220788.1 CDS nagA NC_009480.1 65645 67468 D putative beta-N-acetylglucosaminidase (ZP_00187564.2| COG1472: Beta-glucosidase-related glycosidases [Rubrobacter xylanophilus DSM 9941]; NP_626989.1| beta-N-acetylglucosaminidase (putative secreted protein)[Streptomyces coelicolor A3(2)]). ,InterPro: Glycoside hydrolase family 3 N terminal ,pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915, Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.; Specificity unclear; putative beta-N-acetylglucosaminidase 65645..67468 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173003 YP_001220789.1 CDS ppaB2 NC_009480.1 67885 68886 R conserved hypothetical protein, putative extracellular protease (NP_642686.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]; NP_693914.1| hypothetical protein OB2992 [Oceanobacillus iheyensis HTE831]).; Function unclear; putative extracellular protease complement(67885..68886) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175110 YP_001220790.1 CDS pelA2 NC_009480.1 69085 69936 D putative pectate lyase (NP_625403.1| putative secreted lyase [Streptomyces coelicolor A3(2)]; CAB40884.1| pectate lyase [Bacillus sp. BP-23]). pfam03211, Pectate_lyase, Pectate lyase.; Function unclear; hypothetical protein 69085..69936 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173784 YP_001220791.1 CDS chpC NC_009480.1 70785 71645 R putative extracellular serine protease, family S1 (chymotrypsin) (YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089, Trypsin, Trypsin.; Function unclear; serine protease complement(70785..71645) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175582 YP_001220792.1 CDS chpF NC_009480.1 74779 75633 D putative extracellular serine protease, family S1 (chymotrypsin) (YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089, Trypsin, Trypsin.; Function unclear; serine protease 74779..75633 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175518 YP_001220793.1 CDS CMM_0054 NC_009480.1 76541 77545 R hypothetical protein (NP_954793.1| hypothetical protein [Gordonia westfalica]; NP_940397.1| Hypothetical protein DIP2073 [Corynebacterium diphtheriae NCTC 13129]).; hypothetical protein complement(76541..77545) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175219 YP_001220794.1 CDS CMM_0055 NC_009480.1 77538 78542 R conserved hypothetical protein (NP_940396.1| Hypothetical protein DIP2072 [Corynebacterium diphtheriae]; NP_954792.1| hypothetical protein [Gordonia westfalica]).; Function unclear; hypothetical protein complement(77538..78542) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173218 YP_001220795.1 CDS CMM_0056 NC_009480.1 79094 79756 R hypothetical protein complement(79094..79756) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173230 YP_001220796.1 CDS CMM_0057 NC_009480.1 80653 80916 R hypothetical protein complement(80653..80916) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173235 YP_001220797.1 CDS CMM_0058 NC_009480.1 82453 82716 D hypothetical protein 82453..82716 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173282 YP_001220798.1 CDS chpG NC_009480.1 82939 83772 D putative extracellular serine protease (AAD09893.2| unknown [Clavibacter michiganensis subsp. michiganensis]; BAA06163.1| SAM-P20 serine protease precursor [Streptomyces albogriseolus]). pfam00089, Trypsin,Trypsin.; Conserved hypothetical protein; putative extracellular serine protease 82939..83772 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173248 YP_001220799.1 CDS CMM_0060 NC_009480.1 85126 85584 D hypothetical protein 85126..85584 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175664 YP_001220800.1 CDS CMM_0061 NC_009480.1 85938 86894 D putative cell filamentation protein (ZP_00038266.1| COG2184: Protein involved in cell division [Xylella fastidiosa Dixon]; NP_990877.1| unknown [Achromobacter denitrificans]). pfam02661, Fic, Fic protein family. This family consists of the Fic (filamentation induced by cAMP) protein and its relatives.; Function unclear; putative cell filamentation protein 85938..86894 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173264 YP_001220801.1 CDS CMM_0062 NC_009480.1 91403 91792 D hypothetical protein, putative single-strand binding protein (NP_052579.1| single-strand binding protein homolog Ssb [Corynebacterium glutamicum]; NP_817551.1| gp102 [Mycobacteriophage CJW1]; SSB2_STRCO Single-strand binding protein 2 (SSB 2) (Helix-destabilizing protein 2)). pfam00436, SSB, Single-strand binding protein family. This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.; hypothetical protein 91403..91792 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174792 YP_001220802.1 CDS CMM_0063 NC_009480.1 92168 92875 D conserved hypothetical protein (NP_739263.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00226454.1| hypothetical protein Krad06003337 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 92168..92875 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173310 YP_001220803.1 CDS CMM_0064 NC_009480.1 92944 93639 R putative hydrolase (Q8TWR2|Y970_METKA Putative HAD-hydrolase MK0970; ZP_00310287.1| COG1011: Predicted hydrolase (HAD superfamily) [Cytophaga hutchinsonii]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase.; Function unclear; putative hydrolase complement(92944..93639) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173334 YP_001220804.1 CDS CMM_0065 NC_009480.1 93727 94533 R conserved hypothetical protein, putative phosphotransferase (NP_977552.1| trifolitoxin immunity domain protein [Bacillus cereus ATCC 10987]; ZP_00200969.1| COG3173: Predicted aminoglycoside phosphotransferase [Exiguobacterium sp. 255-15]).; putative phosphotransferase complement(93727..94533) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173348 YP_001220805.1 CDS parX NC_009480.1 94677 95309 D partitioning protein (ZP_00174639.2| COG1192: ATPases involved in chromosome partitioning [Crocosphaera watsonii WH 8501]; NP_940697.1| stability protein [Pseudomonas syringae pv. syringae]). , pfam00991, ParA,ParA family ATPase.; High confidence in function and specificity; partitioning protein 94677..95309 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173317 YP_001220806.1 CDS CMM_0067 NC_009480.1 96096 97265 D putative ATPase (NP_695848.1| hypothetical protein BL0662 [Bifidobacterium longum NCC2705]; NP_940101.1| Conserved hypothetical protein [Corynebacterium diphtheriae NCTC 13129]). pfam01637, Arch_ATPase, Archaeal ATPase. This family contain a conserved P-loop motif that is involved in binding ATP.; Function unclear; putative ATPase 96096..97265 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175476 YP_001220807.1 CDS CMM_0068 NC_009480.1 97383 97616 D hypothetical protein 97383..97616 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173384 YP_001220808.1 CDS nhaA1 NC_009480.1 97673 98977 R Na(+)/H(+) antiporter, NhaA family (ZP_00228734.1| COG3004: Na+/H+ antiporter [Kineococcus radiotolerans SRS30216]; ZP_00058667.1| COG3004: Na+/H+ antiporter [Thermobifida fusca]). pfam06965, Na_H_antiport_1, Na+/H+ antiporter 1. This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyse the exchange of H+ for Na+ in a manner that is highly dependent on the pH.; High confidence in function and specificity; NahA family Na(+)/H(+) antiporter complement(97673..98977) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173371 YP_001220809.1 CDS sbtA NC_009480.1 99640 102741 R subtilisin-like serine protease, peptidase family S8A (CAA07000.1| subtilisin-like protease [Lycopersicon esculentum]; NP_717522.1| serine protease, subtilase family [Shewanella oneidensis MR-1]). , pfam05922,Subtilisin_N, Subtilisin N-terminal Region. This family is found at the N-terminus of a number of subtilisins. It is cleaved prior to activation of the enzyme. , pfam02225,PA, PA domain. The PA (Protease associated) domain is found as an insert domain in diverse proteases.,pfam00082, Peptidase_S8, Subtilase family.; Specificity unclear; subtilisin-like serine protease complement(99640..102741) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175286 YP_001220810.1 CDS ppaE NC_009480.1 103428 104384 R putative serine protease (NP_693914.1| hypothetical protein OB2992 [Oceanobacillus iheyensis HTE831]; ZP_00293497.1| COG3591: V8-like Glu-specific endopeptidase [Thermobifida fusca]; NP_297821.1| hypothetical protein XF0531 [Xylella fastidiosa 9a5c]). pfam00089, Trypsin,Trypsin.; Conserved hypothetical protein; hypothetical protein complement(103428..104384) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175632 YP_001220811.1 CDS CMM_0072 NC_009480.1 106123 106863 R conserved hypothetical protein (NP_631356.1| conserved hypothetical protein SC5F8.11c. [Streptomyces coelicolor A3(2)]; AAD31327.1| beta-lactamase-like protein [Mycobacterium smegmatis]). pfam00753,Lactamase_B, Metallo-beta-lactamase superfamily.; Family membership; hypothetical protein complement(106123..106863) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174216 YP_001220812.1 CDS CMM_0073 NC_009480.1 107334 108860 D putative acyl-CoA synthetase (AMP-forming)(ZP_00294061.1| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Thermobifida fusca]; NP_822779.1| putative acyl-CoA synthetase, long-chain fatty acid:CoA ligase [Streptomyces avermitilis MA-4680]). pfam00501, AMP-binding, AMP-binding enzyme.; Function unclear; putative acyl-CoA synthetase (AMP-forming) 107334..108860 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173402 YP_001220813.1 CDS CMM_0074 NC_009480.1 112168 112389 D conserved hypothetical protein (NP_687579.1| conserved hypothetical protein [Streptococcus agalactiae 2603V/R]; ZP_00224261.1| hypothetical protein Bucepa02001221 [Burkholderia cepacia R1808]).; hypothetical protein 112168..112389 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174652 YP_001220814.1 CDS ppaD NC_009480.1 113031 114005 R putative extracellular serine protease (NP_779169.1| conserved hypothetical protein [Xylella fastidiosa Temecula1]; YP_061793.1| secreted protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293497.1| COG3591: V8-like Glu-specific endopeptidase [Thermobifida fusca]).; Function unclear; putative extracellular serine protease complement(113031..114005) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173438 YP_001220815.1 CDS CMM_0076 NC_009480.1 114879 115307 D hypothetical protein (CAD47974.1| hypothetical protein [Arthrobacter nicotinovorans]).; hypothetical protein 114879..115307 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175387 YP_001220816.1 CDS CMM_0077 NC_009480.1 116970 117137 R hypothetical protein (NP_600530.1| hypothetical protein NCgl1256 [Corynebacterium glutamicum ATCC 13032]; XP_322451.1| predicted protein [Neurospora crassa]); hypothetical protein complement(116970..117137) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173416 YP_001220817.1 CDS CMM_0078 NC_009480.1 117213 118871 D putative NADH oxidase (NP_736949.1| putative pyridine nucleotide-disulphide oxidoreductase [Corynebacterium efficiens YS-314]; NP_654717.1| pyr_redox, Pyridine nucleotide-disulphide oxidoreductase [Bacillus anthracis A2012]). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. pfam00070,Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. pfam02852, Pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain. pfam00581, Rhodanese,Rhodanese-like domain.; Specificity unclear; putative NADH oxidase 117213..118871 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174183 YP_001220818.1 CDS CMM_0079 NC_009480.1 118888 119187 D conserved hypothetical protein (NP_601905.1| rhodanese-related sulfurtransferase [Corynebacterium glutamicum ATCC 13032]; ZP_00058946.1| COG0607: Rhodanese-related sulfurtransferase [Thermobifida fusca]). pfam00581, Rhodanese, Rhodanese-like domain.; Function unclear; hypothetical protein 118888..119187 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173440 YP_001220819.1 CDS CMM_0080 NC_009480.1 119184 119501 D conserved hypothetical protein (NP_736667.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; NP_898741.1| conserved hypothetical protein [Rhodococcus erythropolis]). pfam02583, DUF156,Uncharacterised BCR, COG1937.; Function unclear; hypothetical protein 119184..119501 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173431 YP_001220820.1 CDS CMM_0081 NC_009480.1 119736 120527 R putative oxidoreductase(ZP_00229014.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; YP_004276.1| short chain dehydrogenase [Thermus thermophilus HB27]). InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short-chain dehydrogenase/reductase complement(119736..120527) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173457 YP_001220821.1 CDS bglB NC_009480.1 120538 122925 R putative beta-glycosidase (ZP_00229019.1| COG1472: Beta-glucosidase-related glycosidases [Kineococcus radiotolerans SRS30216]; AAF43783.1| xylosidase/arabinosidase [Thermoanaerobacter ethanolicus]). pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915,Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.; Specificity unclear; putative beta-glucosidase complement(120538..122925) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173451 YP_001220822.1 CDS bglC NC_009480.1 123070 124908 R putative beta-glucosidase/beta-xylosidase (ZP_00214214.1| COG1472: Beta-glucosidase-related glycosidases [Burkholderia cepacia R18194]; S53805 beta-glucosidase/xylosidase - Erwinia chrysanthemi). pfam00933,Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.; Specificity unclear; putative beta-glucosidase/beta-xylosidase complement(123070..124908) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173828 YP_001220823.1 CDS CMM_0084 NC_009480.1 124978 125889 R putative sugar ABC transporter, permease component (ZP_00225485.1| COG0395: ABC-type sugar transport system,permease component [Kineococcus radiotolerans SRS30216]; AAF37729.1| cellobiose transport permease BglB [Thermobifida fusca]). InterPro: Binding-protein-dependent transport systems inner membrane component pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease complement(124978..125889) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173939 YP_001220824.1 CDS CMM_0085 NC_009480.1 125886 126968 R putative sugar ABC transporter, permease component (AAF37728.1| cellobiose transport permease BglA [Thermobifida fusca]; ZP_00226174.1| COG1175: ABC-type sugar transport systems, permease components [Kineococcus radiotolerans SRS30216]; NP_627026.1| putative cellobiose transport permease [Streptomyces coelicolor A3(2)]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease complement(125886..126968) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173504 YP_001220825.1 CDS CMM_0086 NC_009480.1 127043 128320 R putative sugar ABC transporter, binding protein (ZP_00058384.1| COG1653: ABC-type sugar transport system,periplasmic component [Thermobifida fusca]; T46602 cellobiose/cellotriose binding protein [imported] -Streptomyces reticuli (fragment)). pfam01547, SBP_bac_1,Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter binding protein complement(127043..128320) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173547 YP_001220826.1 CDS CMM_0087 NC_009480.1 128542 129288 D putative transcriptional regulator, TetR family (ZP_00120758.1| COG1309: Transcriptional regulator [Bifidobacterium longum DJO10A]; NP_793102.1| transcriptional regulator, TetR family [Pseudomonas syringae pv. tomato str. DC3000]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 128542..129288 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173477 YP_001220827.1 CDS bglA NC_009480.1 129377 130822 R putative beta-glucosidase (NP_631601.1| putative beta-glucosidase [Streptomyces coelicolor A3(2)]; NP_826430.1| putative cellobiose hydrolase [Streptomyces avermitilis MA-4680]). InterPro: Glycoside hydrolase family 1; Specificity unclear; putative beta-glucosidase complement(129377..130822) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173512 YP_001220828.1 CDS catR NC_009480.1 131048 132076 D putative transcriptional regulator, LacI family (AAP57290.1| CatR [Clavibacter michiganensis subsp. michiganensis]; NP_826160.1| putative LacI-family transcriptional regulator [Streptomyces avermitilis MA-4680]). InterPro: Periplasmic binding proteins and sugar binding domain LacI family pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The periplasmic binding proteins are the primary receptors for chemotaxis and transport of many sugar based solutes. The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain (pfam00356).; Specificity unclear; LacI family transcriptional regulator 131048..132076 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174035 YP_001220829.1 CDS tomA NC_009480.1 132170 133801 R tomatinase, glycosyl hydrolase, family 10 (ZP_00192175.3| COG3693: Beta-1,4-xylanase [Kineococcus radiotolerans SRS30216]; CAA10112.1| tomatinase [Fusarium oxysporum f. sp. lycopersici]). , pfam00331,Glyco_hydro_10, Glycosyl hydrolase family 10.; High confidence in function and specificity; tomatinase, endo-1,4-beta-glycosidase complement(132170..133801) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175749 YP_001220830.1 CDS regB NC_009480.1 134140 134811 R putative two-component system response regulator (ZP_00199394.2| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]; NP_625364.1| putative two component system response regulator [Streptomyces coelicolor A3(2)]). cd00156, REC, Signal receiver domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system response regulator complement(134140..134811) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175885 YP_001220831.1 CDS regA NC_009480.1 134808 135962 R putative two-component system sensor kinase (ZP_00192164.3| COG4585: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]; NP_827214.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]).; Specificity unclear; putative two-component system sensor kinase complement(134808..135962) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174372 YP_001220832.1 CDS CMM_0093 NC_009480.1 135959 138130 R putative exporter of the RND family (ZP_00229024.1| COG2409: Predicted drug exporters of the RND superfamily [Kineococcus radiotolerans SRS30216]; NP_631580.1| putative integral membrane protein. [Streptomyces coelicolor A3(2)]). InterPro: HMGCR/Patched 5TM box; Specificity unclear; RND family transporter complement(135959..138130) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175976 YP_001220833.1 CDS cytA NC_009480.1 138337 139557 D cytochrome P450 (ZP_00229013.1| COG2124: Cytochrome P450 [Kineococcus radiotolerans SRS30216]; CAE53708.1| putative cytochrome P450 [Streptomyces peucetius])., ,pfam00067, p450, Cytochrome P450. Cytochrome P450s are involved in the oxidative degradation of various compounds.; Specificity unclear; cytochrome P450 138337..139557 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173566 YP_001220834.1 CDS cytB NC_009480.1 139554 139751 D putative 3Fe-4S ferredoxin (P18325|FER2_STRGO Ferredoxin 2 (Fd-2); P46374|FAS2_RHOFA Ferredoxin fas2).; Function unclear; putative 3Fe-4S ferredoxin 139554..139751 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175085 YP_001220835.1 CDS cytC NC_009480.1 139748 140950 D Ferredoxin Reductase (P450 system) (NP_822785.1| putative ferredoxin reductase [Streptomyces avermitilis MA-4680]; ZP_00229012.1| COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases [Kineococcus radiotolerans SRS30216]). pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.; Specificity unclear; putative ferredoxin reductase 139748..140950 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175202 YP_001220836.1 CDS bglD NC_009480.1 141009 143633 R putative beta-glucosidase, glycosyl hydrolase family 3 (ZP_00229019.1| COG1472: Beta-glucosidase-related glycosidases [Kineococcus radiotolerans SRS30216]; AAF43783.1| xylosidase/arabinosidase [Thermoanaerobacter ethanolicus]). pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915,Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.; Specificity unclear; glycosyl hydrolase family beta-glucosidase complement(141009..143633) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174269 YP_001220837.1 CDS CMM_0098 NC_009480.1 143748 144755 R putative transcriptional regulator, LacI-family (emb|CAD47864.1| putative LacI-family transcriptional regulator [Arthrobacter nicotinovorans]; NP_963234.1| hypothetical protein MAP4300 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The periplasmic binding proteins are the primary receptors for chemotaxis and transport of many sugar based solutes. The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain (pfam00356).; Specificity unclear; LacI family transcriptional regulator complement(143748..144755) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174851 YP_001220838.1 CDS bglE NC_009480.1 144980 147469 D putative beta-galactosidase/beta-glucuronidase (ZP_00229015.1| COG3250: Beta-galactosidase/beta-glucuronidase [Kineococcus radiotolerans SRS30216]; ZP_00061173.1| COG3250: Beta-galactosidase/ beta-glucuronidase [Clostridium thermocellum ATCC 27405]). InterPro: Glycoside hydrolase family 2 pfam02837,Glyco_hydro_2_N, Glycosyl hydrolases family 2, sugar binding domain. pfam02836, Glyco_hydro_2_C, Glycosyl hydrolases family 2, TIM barrel domain.; Specificity unclear; hypothetical protein 144980..147469 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173585 YP_001220839.1 CDS bglF NC_009480.1 147484 149739 D putative beta-glucosidase, glycosyl hydrolase family 3 (ZP_00229018.1| COG1472: Beta-glucosidase-related glycosidases [Kineococcus radiotolerans SRS30216]; ZP_00060124.1| COG1472: Beta-glucosidase- related glycosidases [Clostridium thermocellum ATCC 27405]). pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915, Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.; Specificity unclear; beta-galactosidase 147484..149739 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175285 YP_001220840.1 CDS bglG NC_009480.1 149904 151076 D putative beta-glucosidase, glycosyl hydrolase family 1 (ZP_00192144.3| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Kineococcus radiotolerans SRS30216]; CAA52344.1| beta-glucosidase [Streptomyces rochei]). InterPro: Glycoside hydrolase family 1. pfam00232, Glyco_hydro_1, Glycosyl hydrolase family 1.; Specificity unclear; beta-galactosidase 149904..151076 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174629 YP_001220841.1 CDS bglH NC_009480.1 151096 152694 D putative beta-galactosidase, glycosyl hydrolase family 35 (ZP_00229011.1| COG1874: Beta-galactosidase [Kineococcus radiotolerans SRS30216]; NP_642855.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]). pfam01301, Glyco_hydro_35, Glycosyl hydrolases family 35.; Specificity unclear; putative beta-galactosidase 151096..152694 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173286 YP_001220842.1 CDS bglI NC_009480.1 152728 154494 R putative beta-xylosidase, glycosyl hydrolase family 43 (14-beta-D-xylan xylohydrolase) (NP_244550.1| xylan beta-1,4-xylosidase [Bacillus halodurans C-125]; ZP_00066469.1| COG3507: Beta-xylosidase [Microbulbifer degradans 2-40]). pfam04616, Glyco_hydro_43, Glycosyl hydrolases family 43. cd00057, FA58C, Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.; Specificity unclear; beta-xylosidase glycosyl hydrolase family 43 complement(152728..154494) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173833 YP_001220843.1 CDS CMM_0104 NC_009480.1 154629 156008 D putative sugar permease (MFS superfamily) (ZP_00229022.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; CAD47966.1| hypothetical protein [Arthrobacter nicotinovorans]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; sugar permease 154629..156008 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174063 YP_001220844.1 CDS ramA NC_009480.1 156005 158506 D putative alpha rhamnosidase (ZP_00229021.1| hypothetical protein Krad06000075 [Kineococcus radiotolerans SRS30216]; AAR96046.1| alpha-L-rhamnosidase A [Thermomicrobia bacterium PRI-1686]). , weak similarities to: COG3408, GDB1, Glycogen debranching enzyme; pfam05592, Bac_rhamnosid, Bacterial alpha-L-rhamnosidase. This family consists of bacterial rhamnosidase A and B enzymes. L-Rhamnose is abundant in biomass as a common constituent of glycolipids and glycosides, such as plant pigments, pectic polysaccharides, gums or biosurfactants.; Specificity unclear; putative alpha-rhamnosidase 156005..158506 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173572 YP_001220845.1 CDS aglA NC_009480.1 159396 161624 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase complement(159396..161624) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173716 YP_001220846.1 CDS CMM_0107 NC_009480.1 161748 162659 R putative sugar ABC transporter, permease compound (NP_822503.1| putative binding-protein dependent transport protein [Streptomyces avermitilis MA-4680]; ZP_00121009.2| COG0395: ABC-type sugar transport system,permease component [Bifidobacterium longum DJO10A]).; Specificity unclear; putative sugar ABC transporter permease compound complement(161748..162659) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175505 YP_001220847.1 CDS CMM_0108 NC_009480.1 162659 163621 R putative sugar ABC transporter, permease component (NP_822502.1| putative binding-protein dependent transport protein [Streptomyces avermitilis MA-4680]; ZP_00227865.1| COG1175: ABC-type sugar transport systems,permease components [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative sugar ABC transporter permease complement(162659..163621) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173628 YP_001220848.1 CDS CMM_0109 NC_009480.1 163695 165053 R putative sugar ABC transporter, binding protein (NP_822501.1| putative solute-binding lipoprotein [Streptomyces avermitilis MA-4680]; ZP_00227866.1| COG1653: ABC-type sugar transport system, periplasmic component [Kineococcus radiotolerans SRS30216]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter binding protein complement(163695..165053) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173664 YP_001220849.1 CDS CMM_0110 NC_009480.1 165201 166802 D putative xylosidase (NP_693008.1| xylosidase; arabinofuranosidase [Oceanobacillus iheyensis HTE831]; XYLB_BUTFI Xylosidase/arabinosidase [Includes: Beta-xylosidase (1,4-beta-D-xylan xylohydrolase) (Xylan 1,4-beta-xylosidase); Alpha-N-arabinofuranosidase (Arabinosidase)]). pfam04616, Glyco_hydro_43, Glycosyl hydrolases family 43.; Specificity unclear; xylosidase glycosyl hydrolase family protein 165201..166802 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173684 YP_001220850.1 CDS CMM_0111 NC_009480.1 166885 167691 D putative sugar phosphate isomerase/epimerase (ZP_00229027.1| COG1082: Sugar phosphate isomerases/epimerases [Kineococcus radiotolerans SRS30216]; NP_774276.1| bll7636 [Bradyrhizobium japonicum USDA 110]).; Function unclear; putative sugar phosphate isomerase/epimerase 166885..167691 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173614 YP_001220851.1 CDS CMM_0112 NC_009480.1 167688 168797 D putative dehydrogenase/oxidoreductase (ZP_00227973.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_241574.1| BH0708~unknown conserved protein [Bacillus halodurans C-125]). pfam01408, GFO_IDH_MocA,Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD.; Function unclear; putative dehydrogenase/oxidoreductase 167688..168797 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173741 YP_001220852.1 CDS CMM_0113 NC_009480.1 168891 169622 D putative hydrolase (ZP_00194950.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Mesorhizobium sp. BNC1]; ZP_00024553.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Ralstonia metallidurans]).; Function unclear; putative hydrolase 168891..169622 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173695 YP_001220853.1 CDS CMM_0114 NC_009480.1 169619 170332 D hypothetical protein (NP_624727.1| hypothetical protein SCF51.05 [Streptomyces coelicolor A3(2)]; NP_601349.1| hypothetical protein NCgl2067 [Corynebacterium glutamicum ATCC 13032]). contains COG1413, FOG: HEAT repeat.; hypothetical protein 169619..170332 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173768 YP_001220854.1 CDS CMM_0115 NC_009480.1 170415 171371 D putative transcriptional regulator, MerR family (ZP_00191993.3| COG0789: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]; NP_822962.1| putative MerR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00376,MerR, MerR family regulatory protein.; Specificity unclear; hypothetical protein 170415..171371 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173085 YP_001220855.1 CDS CMM_0116 NC_009480.1 171496 172086 D putative dienelactone hydrolase (ZP_00210010.1| COG0412: Dienelactone hydrolase and related enzymes [Magnetospirillum magnetotacticum]; ZP_00228563.1| COG0412: Dienelactone hydrolase and related enzymes [Kineococcus radiotolerans SRS30216]). pfam01738, DLH,Dienelactone hydrolase family.; Specificity unclear; putative dienelactone hydrolase 171496..172086 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173806 YP_001220856.1 CDS CMM_0117 NC_009480.1 172096 173580 R putative drug-resistance MFS transporter (S70171 integral membrane protein - Streptomyces pristinaespiralis; NP_628206.1| putative integral membrane efflux protein [Streptomyces coelicolor A3(2)]). InterPro: General substrate transporters 14 transmembrane helices; Specificity unclear; putative MFS-type efflux protein complement(172096..173580) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173796 YP_001220857.1 CDS CMM_0118 NC_009480.1 173663 174409 D putative TetR-family transcriptional regulator (NP_631278.1| putative TetR-family transcriptional regulator (NP_631278.1| putative TetR-family transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_792454.1| transcriptional regulator, TetR family [Pseudomonas syringae pv. tomato str. DC3000]). pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.; Specificity unclear; TetR family transcriptional regulator 173663..174409 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173758 YP_001220858.1 CDS CMM_0119 NC_009480.1 174435 175130 R putative transcriptional regulator, TetR family (NP_827877.1| putative TetR-family transcriptional regulator (NP_827877.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_737549.1| transcription regulator AmtR [Corynebacterium efficiens YS-314]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator complement(174435..175130) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173845 YP_001220859.1 CDS uahA NC_009480.1 175154 178837 R putative urea amidolyase (NP_923904.1| probable urea amidolyase [Gloeobacter violaceus PCC 7421]; NP_946755.1| putative urea amidolyase [Rhodopseudomonas palustris CGA009]). domain combination of urea hydrolase related proteins: pfam00289, CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain. pfam02786,CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain. pfam02785, Biotin_carb_C, Biotin carboxylase C-terminal domain. pfam02626, AHS2,Allophanate hydrolase subunit 2. pfam02682, AHS1,Allophanate hydrolase subunit 1. pfam00364, Biotin_lipoyl,Biotin-requiring enzyme.; High confidence in function and specificity; putative urea amidolyase complement(175154..178837) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173871 YP_001220860.1 CDS CMM_0121 NC_009480.1 178834 179526 R conserved hypothetical protein (NP_737324.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00225763.1| COG3665: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein complement(178834..179526) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175764 YP_001220861.1 CDS CMM_0122 NC_009480.1 179523 180365 R conserved hypothetical protein (ZP_00225764.1| COG3665: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_737325.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; Function unclear; hypothetical protein complement(179523..180365) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173890 YP_001220862.1 CDS CMM_0123 NC_009480.1 180362 181945 R putative amino-acid permease, APC family (ZP_00225765.1| COG0531: Amino acid transporters [Kineococcus radiotolerans SRS30216]; NP_827885.1| putative amino acid/metabolite permease [Streptomyces avermitilis MA-4680])., pfam00324, AA_permease, Amino acid permease.; Specificity unclear; amino acid permease complement(180362..181945) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173959 YP_001220863.1 CDS CMM_0124 NC_009480.1 182195 185590 R putative acyl-CoA synthetase (AAR91681.1| ATP/NADPH-dependent carboxylic acid reductase [Nocardia sp. NRRL 5646]; NP_959974.1| FadD9 [Mycobacterium avium subsp. paratuberculosis str. k10])., N-terminal domain: COG1022,FAA1, Long-chain acyl-CoA synthetases (AMP-forming),pfam00501, AMP-binding, AMP-binding enzyme. pfam00550, PP-binding, Phosphopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. , C-terminal domain: COG3320, COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes acyl_carrier: acyl carrier protein, may be involved in the activation of fatty acids or part of a PKS/NRPS.; Specificity unclear; putative acyl-CoA synthetase complement(182195..185590) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173995 YP_001220864.1 CDS CMM_0125 NC_009480.1 185595 186320 R putative 4-phosphopantetheinyl transferase (Enterobactin synthetase component D) (NP_822924.1| putative phosphopantetheinyl transferase [Streptomyces avermitilis MA-4680]; AAR92400.1| Sfp-type phosphopantetheinyl transferase [Saccharopolyspora erythraea]).; Function unclear; putative 4-phosphopantetheinyl transferase complement(185595..186320) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173924 YP_001220865.1 CDS CMM_0126 NC_009480.1 186504 187316 R hypothetical protein (EAM74364.1| hypothetical protein KradDRAFT_1431 [Kineococcus radiotolerans SRS30216]; ZP_00413143.1| hypothetical protein ArthDRAFT_2026 [Arthrobacter sp. FB24]).; hypothetical protein complement(186504..187316) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173975 YP_001220866.1 CDS sigX NC_009480.1 187313 187864 R putative RNA polymerase ECF-subfamily sigma factor (NP_627178.1| putative RNA polymerase sigma factor [Streptomyces coelicolor A3(2)]; YP_121728.1| putative sigma factor [Nocardia farcinica IFM 10152]). pfam04542,Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. pfam04545,Sigma70_r4, Sigma-70, region 4.; Specificity unclear; RNA polymerase ECF-subfamily sigma factor complement(187313..187864) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174048 YP_001220867.1 CDS CMM_0128 NC_009480.1 188085 188795 D conserved hypothetical protein (XP_390017.1| hypothetical protein FG09841.1 [Gibberella zeae PH-1]; NP_923811.1| hypothetical protein gll0865 [Gloeobacter violaceus PCC 7421]).; hypothetical protein 188085..188795 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173832 YP_001220868.1 CDS CMM_0129 NC_009480.1 188801 189469 D putative sortase (NP_631498.1| putative secreted protein [Streptomyces coelicolor A3(2)]; NP_693584.1| hypothetical protein OB2663 [Oceanobacillus iheyensis HTE831]). cd00004, Sortase, Sortase domain; transpeptidase of Gram-positive bacteria, cleaves surface proteins at the LPXTG motif between Thr and Gly and catalyzes the formation of an amide bond between the carboxyl group of Thr and the amino group of cell-wall crossbridges. In two different classes of sortases the N-terminus either functions as both a signal peptide for secretion and a stop-transfer signal for membrane anchoring, or it contains a signal peptide only and the C-terminus serves as a membrane anchor. pfam04203, Sortase, Sortase family. The founder member of this family is S.aureus sortase, a transpeptidase that attaches surface proteins by the threonine of an LPXTG motif to the cell wall.; Family membership; putative sortase 188801..189469 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174019 YP_001220869.1 CDS CMM_0130 NC_009480.1 189495 189755 R hypothetical protein (; hypothetical protein complement(189495..189755) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174101 YP_001220870.1 CDS CMM_0131 NC_009480.1 189769 190011 R hypothetical protein complement(189769..190011) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174036 YP_001220871.1 CDS CMM_0132 NC_009480.1 190129 191409 R hypothetical protein (only weak similarities to RTX toxins (ZP_00116833.1| COG2931: RTX toxins and related Ca2+-binding proteins [Cytophaga hutchinsonii]) and phage capsid proteins (NP_861884.1| Hoc head outer capsid protein [Enterobacteria phage RB69])).; hypothetical protein complement(190129..191409) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174084 YP_001220872.1 CDS CMM_0133 NC_009480.1 191551 192192 D putative cysteine peptidase, family C15 (NP_931479.1| Pyrrolidone- carboxylate peptidase (5-oxoprolyl-peptidase) [Photorhabdus luminescens subsp. laumondii TTO1]; ZP_00024570.1| COG2039: Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) [Ralstonia metallidurans]). pfam01470, Peptidase_C15,Pyroglutamyl peptidase.; Function unclear; putative pyroglutamylpeptidase 191551..192192 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174160 YP_001220873.1 CDS CMM_0134 NC_009480.1 192438 193625 D putative FAD-dependent monooxygenase (ZP_00216251.1| COG0654: 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Burkholderia cepacia R18194]; NP_771617.1| blr4977 [Bradyrhizobium japonicum USDA 110]). pfam01360,Monooxygenase, Monooxygenase. This family includes diverse enzymes that utilise FAD.; Specificity unclear; hypothetical protein 192438..193625 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174137 YP_001220874.1 CDS CMM_0135 NC_009480.1 193999 194973 R conserved hypothetical protein, weakly ; ZP_00239107.1| GTP pyrophosphokinase [Bacillus cereus G9241])., , pfam04607, RelA_SpoT, Region found in RelA / SpoT proteins.; hypothetical protein complement(193999..194973) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174203 YP_001220875.1 CDS CMM_0136 NC_009480.1 194970 196007 R hypothetical protein (AAN62299.1| hypothetical protein [Pseudomonas aeruginosa]; AAW89695.1| hypothetical protein, putative phage associated protein [Neisseria gonorrhoeae FA 1090]).; hypothetical protein complement(194970..196007) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174261 YP_001220876.1 CDS CMM_0137 NC_009480.1 196333 197721 R putative MFS transporter (CAF21275.1| Permease of the major facilitator superfamily [Corynebacterium glutamicum ATCC 13032]; NP_961251.1| hypothetical protein MAP2317c [Mycobacterium avium subsp. paratuberculosis str. k10]).; Specificity unclear; putative MFS transporter complement(196333..197721) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174233 YP_001220877.1 CDS CMM_0138 NC_009480.1 197794 198540 D putative kinase/phosphotransferase (weak similarity to COG3173, Predicted aminoglycoside phosphotransferase [General function prediction only]; ZP_00200969.1| COG3173: Predicted aminoglycoside phosphotransferase [Exiguobacterium sp. 255-15]; NP_655042.1| Choline_kinase, Choline/ethanolamine kinase [Bacillus anthracis A2012]).; Function unclear; hypothetical protein 197794..198540 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174332 YP_001220878.1 CDS CMM_0139 NC_009480.1 198545 198928 R conserved hypothetical protein (ZP_00074096.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Trichodesmium erythraeum IMS101]; NP_765595.1| mutator protein mutT [Staphylococcus epidermidis ATCC 12228]). pfam00293, NUDIX, NUDIX domain.; Family membership; hypothetical protein complement(198545..198928) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174407 YP_001220879.1 CDS CMM_0140 NC_009480.1 198943 199437 R transcriptional regulator, MarR family (NP_977771.1| transcriptional regulator, MarR family [Bacillus cereus ATCC 10987]; ZP_00037950.1| COG1846: Transcriptional regulators [Enterococcus faecium]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; hypothetical protein complement(198943..199437) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174297 YP_001220880.1 CDS CMM_0141 NC_009480.1 199666 200331 D hypothetical protein 199666..200331 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174393 YP_001220881.1 CDS CMM_0142 NC_009480.1 200413 201393 D hypothetical protein; putative serine peptidase,family S26 (NP_563211.1| signal peptidase type I [Clostridium perfringens str. 13]), , pfam00461,Peptidase_S26, Signal peptidase I.; hypothetical protein 200413..201393 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174429 YP_001220882.1 CDS CMM_0143 NC_009480.1 201390 202232 D hypothetical protein , cd00110, LamG, Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans.; hypothetical protein 201390..202232 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174445 YP_001220883.1 CDS CMM_0144 NC_009480.1 202285 203268 R conserved hypothetical protein (NP_929594.1| hypothetical protein [Photorhabdus luminescens subsp. laumondii TTO1]; AAM97361.1| RubK [Streptomyces collinus]).; Function unclear; hypothetical protein complement(202285..203268) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174458 YP_001220884.1 CDS CMM_0145 NC_009480.1 203637 204329 R hypothetical protein (NP_925435.1| unknown protein [Gloeobacter violaceus PCC 7421]).; hypothetical protein complement(203637..204329) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174529 YP_001220885.1 CDS CMM_0146 NC_009480.1 204455 205099 R hypothetical protein weak similarity to: NP_831063.1| Cell envelope-bound metalloprotease (camelysin) [Bacillus cereus ATCC 14579]; putative peptidase complement(204455..205099) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174618 YP_001220886.1 CDS CMM_0147 NC_009480.1 205099 205731 R putative signal peptidase I (Leader peptidase I) (AAN08877.1| signal peptidase type I [Leishmania major]; AAF02220.1| signal peptidase type I [Bacillus amyloliquefaciens]). pfam00461, Peptidase_S26, Signal peptidase I.; hypothetical protein complement(205099..205731) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174464 YP_001220887.1 CDS CMM_0148 NC_009480.1 205728 206537 R hypothetical protein complement(205728..206537) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174561 YP_001220888.1 CDS CMM_0149 NC_009480.1 206653 207351 R hypothetical protein, weak similarity to: NP_834566.1| Cell envelope-bound metalloprotease (camelysin) [Bacillus cereus ATCC 14579]; hypothetical protein complement(206653..207351) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174646 YP_001220889.1 CDS CMM_0150 NC_009480.1 207498 210902 R hypothetical protein (EAL12040.1| cell wall surface anchor family protein, putative [Bacillus cereus G9241]; ZP_00117602.1| COG2931: RTX toxins and related Ca2+-binding proteins [Cytophaga hutchinsonii]). , weak similarity to cell surface proteins and invasin.; Conserved hypothetical protein; putative cell wall surface anchor family protein complement(207498..210902) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174699 YP_001220890.1 CDS dnaK NC_009480.1 211308 213179 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 211308..213179 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174769 YP_001220891.1 CDS grpE NC_009480.1 213176 213829 D heat shock chaperone (HSP-70 cofactor)(NP_695711.1| GrpE protein [Bifidobacterium longum NCC2705]; NP_787877.1| HSP-70 cofactor GrpE [Tropheryma whipplei str. Twist]). Stimulates jointly with dnaJ the ATPAse activity of dnaK. Helps to release ADP from dnaK thus allowing dnaK to recycle more efficiently (By similarity). pfam01025, GrpE, GrpE.; High confidence in function and specificity; heat shock chaperone 213176..213829 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173896 YP_001220892.1 CDS dnaJ1 NC_009480.1 213950 214963 D chaperone (NP_789681.1| molecular chaperone DnaJ [Tropheryma whipplei TW08/27]; ZP_00225596.1| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger domain [Kineococcus radiotolerans SRS30216]). pfam00226,DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. , pfam01556, DnaJ_C, DnaJ C terminal region.; High confidence in function and specificity; chaperone, curved DNA-binding protein 213950..214963 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174590 YP_001220893.1 CDS hspR NC_009480.1 214965 215438 D putative transcriptional regulator, MerR family (ZP_00056688.1| COG0789: Predicted transcriptional regulators [Thermobifida fusca]; NP_825664.1| putative HspR protein [Streptomyces avermitilis MA-4680]). PUTATIVE HEAT SHOCK REGULATOR pfam00376, MerR, MerR family regulatory protein.; Specificity unclear; heat shock transcriptional regulator 214965..215438 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174725 YP_001220894.1 CDS CMM_0155 NC_009480.1 215435 216658 D putative methyltransferase (NP_625336.1| conserved hypothetical protein SCG20A.21 [Streptomyces coelicolor A3(2)]; ZP_00138173.1| COG2813: 16S RNA G1207 methylase RsmC [Pseudomonas aeruginosa CBPP-PA14]). , , pfam05175,MTS, Methyltransferase small domain., InterPro: SAM (and some other nucleotide) binding motif.; Function unclear; putative methyltransferase 215435..216658 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175623 YP_001220895.1 CDS CMM_0156 NC_009480.1 216711 217151 D conserved hypothetical protein (ZP_00067078.1| hypothetical protein [Microbulbifer degradans 2-40]; NP_266258.1| hypothetical protein L103661 [Lactococcus lactis subsp. lactis Il1403]).; hypothetical protein 216711..217151 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174757 YP_001220896.1 CDS CMM_0157 NC_009480.1 217183 217419 R putative transcriptional regulator, Cro/CI family (ZP_00225419.1| COG3655: Predicted transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_656871.1| HTH_XRE, Helix-turn-helix XRE-family like proteins [Bacillus anthracis A2012]). smart00530, HTH_XRE,Helix-turn-helix XRE-family like proteins. pfam01381,HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator complement(217183..217419) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174671 YP_001220897.1 CDS CMM_0158 NC_009480.1 217419 218057 R Hypothetical protein; hypothetical protein complement(217419..218057) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174779 YP_001220898.1 CDS CMM_0159 NC_009480.1 218138 218584 R conserved hypothetical protein, FAD binding protein (AAQ61023.1| conserved hypothetical protein [Chromobacterium violaceum ATCC 12472]; NP_738977.1| hypothetical protein [Corynebacterium efficiens YS-314]). pfam04940, BLUF, Sensors of blue-light using FAD. The BLUF domain has been shown to bind FAD in the AppA protein.; hypothetical protein complement(218138..218584) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174738 YP_001220899.1 CDS CMM_0160 NC_009480.1 218974 219702 R hypothetical protein complement(218974..219702) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174811 YP_001220900.1 CDS CMM_0161 NC_009480.1 219867 220895 R putative LacI-family transcriptional regulator (NP_936186.1| transcriptional regulator [Vibrio vulnificus YJ016]; AAC82367.1| catabolite control protein A [Thermoactinomyces sp. E79]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain (pfam00356).; Specificity unclear; LacI family transcriptional regulator complement(219867..220895) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174967 YP_001220901.1 CDS CMM_0162 NC_009480.1 221482 222105 R conserved hypothetical protein, possible flavoprotein oxygenase (ZP_00217975.1| COG1853: Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [Burkholderia cepacia R18194]; NP_244852.1| BH3984~unknown conserved protein [Bacillus halodurans C-125]).; hypothetical protein complement(221482..222105) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174872 YP_001220902.1 CDS CMM_0163 NC_009480.1 222222 223250 D hypothetical protein 222222..223250 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175023 YP_001220903.1 CDS CMM_0164 NC_009480.1 223454 224224 D hypothetical protein (only very weak similarities to e. g. ZP_00213268.1| COG2755: Lysophospholipase L1 and related esterases [Burkholderia cepacia R18194]).; hypothetical protein 223454..224224 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175091 YP_001220904.1 CDS fhuC NC_009480.1 224275 225177 D putative Fe3+-siderophore ABC transpoter, ATPase component (NP_631450.1| putative ABC-transport protein,ATP-binding component [Streptomyces coelicolor A3(2)]; ZP_00203479.1| COG1120: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Anabaena variabilis ATCC 29413]). pfam00005, ABC_tran,ABC transporter.; Specificity unclear; putative Fe3+-siderophore ABC transporterATPase 224275..225177 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174980 YP_001220905.1 CDS fhuD NC_009480.1 225174 226163 D putative Fe3+-siderophore ABC transporter, binding protein (NP_631449.1| possible binding-protein-dependent transport lipoprotein [Streptomyces coelicolor A3(2)]; YP_038579.1| iron compound ABC transporter, iron compound-binding protein [Bacillus thuringiensis serovar konkukian str. 97-27]).; Specificity unclear; putative Fe3+-siderophore ABC transporterbinding protein 225174..226163 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173486 YP_001220906.1 CDS fhuB NC_009480.1 226198 228354 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 226198..228354 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173503 YP_001220907.1 CDS CMM_0167a NC_009480.1 228475 228960 D putative membrane protein (ZP_00299182.1| COG2259: Predicted membrane protein [Geobacter metallireducens GS-15]; ZP_00187970.1| hypothetical protein Rxyl02000785 [Rubrobacter xylanophilus DSM 9941]). weak similarity to: pfam07291, MauE, Methylamine utilisation protein MauE.; hypothetical protein 228475..228960 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173419 YP_001220908.1 CDS CMM_0168 NC_009480.1 229937 231484 D putative two-component system sensor kinase (NP_628759.1| putative two-component system sensor kinase [Streptomyces coelicolor A3(2)]; NP_826056.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 229937..231484 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175059 YP_001220909.1 CDS CMM_0169 NC_009480.1 231511 232173 D putative two-component system response regulator (NP_826055.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]; ZP_00198576.2| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]). pfam00196, GerE,Bacterial regulatory proteins, luxR family. pfam00072,Response_reg, Response regulator receiver domain.; Specificity unclear; putative two-component system response regulator 231511..232173 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175107 YP_001220910.1 CDS CMM_0170 NC_009480.1 232240 232644 D putative tautomerase (ZP_00209270.1| COG1942: Uncharacterized protein, 4-oxalocrotonate tautomerase homolog [Magnetospirillum magnetotacticum]; P94502|YRDN_BACSU Probable tautomerase yrdN). pfam01361,Tautomerase, Tautomerase enzyme. This family includes the enzyme 4-oxalocrotonate tautomerase that catalyses the ketonisation of 2-hydroxymuconate to 2-oxo-3-hexenedioate.; Function unclear; putative tautomerase 232240..232644 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175184 YP_001220911.1 CDS CMM_0171 NC_009480.1 232668 233180 R putative acetyltransferase, GnaT family (NP_899804.1| probable putative acetyltransferase [Chromobacterium violaceum ATCC 12472]; ZP_00058960.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(232668..233180) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175171 YP_001220912.1 CDS CMM_0172 NC_009480.1 233252 234946 R conserved hypothetical protein (AAD02119.1| unknown [Streptomyces toyocaensis]; ZP_00226047.1| COG0595: Predicted hydrolase of the metallo-beta-lactamase superfamily [Kineococcus radiotolerans SRS30216]). pfam00753, Lactamase_B, Metallo-beta-lactamase superfamily.; Family membership; hypothetical protein complement(233252..234946) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175380 YP_001220913.1 CDS sulP NC_009480.1 235445 236977 D putative sulfate MFS permease (NP_627488.1| putative integral membrane transporter [Streptomyces coelicolor A3(2)]; NP_862402.1| putative integral membrane transporter [Micrococcus sp. 28]). pfam00916,Sulfate_transp, Sulfate transporter family. TIGRFAM (TIGR00815): sulfate permease sulP. pfam01740, STAS, STAS domain. The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.; High confidence in function and specificity; putative sulfate MFS permease 235445..236977 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175316 YP_001220914.1 CDS mntA NC_009480.1 237042 237698 R putative Mn2+/Zn2+ ABC-type transporter, ATPase component (NP_624795.1| ABC transport protein, ATP-binding subunit [Streptomyces coelicolor A3(2)]; NP_599281.1| ABC-type transporter, ATPase component [Corynebacterium glutamicum ATCC 13032]). most likely involved in Zn2+ and/or Mn2+ uptake. pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative Mn2+/Zn2+ ABC-type transporter, ATPase complement(237042..237698) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175729 YP_001220915.1 CDS mntB NC_009480.1 237755 238624 D putative Mn2+/Zn2+ ABC-type transporter, permease component (NP_599280.1| ABC-type transporter, permease component [Corynebacterium glutamicum ATCC 13032]; NP_624794.1| ABC transporter protein, integral membrane subunit [Streptomyces coelicolor A3(2)]).; Specificity unclear; putative Mn2+/Zn2+ ABC transporter permease 237755..238624 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175288 YP_001220916.1 CDS CMM_0176 NC_009480.1 238675 239907 D conserved hypothetical protein, putatively secreted (NP_599278.1| hypothetical protein NCgl0025 [Corynebacterium glutamicum ATCC 13032]; NP_624793.1| putative lipoprotein [Streptomyces coelicolor A3(2)]).; hypothetical protein 238675..239907 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175656 YP_001220917.1 CDS mntC NC_009480.1 239904 240830 D putative manganese ABC transporter, substrate-binding lipoprotein (NP_599279.1| ABC-type transporter,periplasmic component [Corynebacterium glutamicum ATCC 13032]; NP_624792.1| putative solute-binding lipoprotein [Streptomyces coelicolor A3(2)]). InterPro: Adhesion lipoprotein family pfam01297, SBP_bac_9, Periplasmic solute binding protein family.; Specificity unclear; putative Mn2+/Zn2+ ABC transporter substrate binding protein 239904..240830 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175267 YP_001220918.1 CDS CMM_0178 NC_009480.1 240866 242077 D conserved hypothetical protein (NP_624791.1| putative secreted protein [Streptomyces coelicolor A3(2)]; NP_599278.1| hypothetical protein NCgl0025 [Corynebacterium glutamicum ATCC 13032]).; hypothetical protein 240866..242077 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175684 YP_001220919.1 CDS CMM_0179 NC_009480.1 242217 243596 D NAD-dependent aldehyde dehydrogenase (AAN37492.1| 6-oxohexanoate dehydrogenase; ChnE [Rhodococcus sp. Phi2]; O32507|GABD_DEIRA Succinate-semialdehyde dehydrogenase [NADP+] (SSDH)). pfam00171, Aldedh, Aldehyde dehydrogenase family.; Specificity unclear; NAD-dependent aldehyde dehydrogenase 242217..243596 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174892 YP_001220920.1 CDS CMM_0180 NC_009480.1 243680 244027 D hypothetical protein 243680..244027 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173539 YP_001220921.1 CDS CMM_0181 NC_009480.1 244054 245394 R putative glycosyltransferase (YP_051468.1| putative glycosyltransferase [Erwinia carotovora subsp. atroseptica SCRI1043]; AAN01207.1| putative glycosyltransferase [Lechevalieria aerocolonigenes]). pfam00201, UDPGT, UDP-glucoronosyl and UDP-glucosyl transferase.; Function unclear; putative glycosyltransferase complement(244054..245394) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173487 YP_001220922.1 CDS CMM_0182 NC_009480.1 245483 245749 R hypothetical protein complement(245483..245749) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173168 YP_001220923.1 CDS CMM_0183 NC_009480.1 245857 247074 D putative aminotransferase (Q9CBM9|YM94_MYCLE Putative aminotransferase ML1794; NP_625035.1| putative transferase [Streptomyces coelicolor A3(2)]). pfam00155,Aminotran_1_2, Aminotransferase class I and II.; Function unclear; hypothetical protein 245857..247074 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174806 YP_001220924.1 CDS metE1 NC_009480.1 247071 248258 D putative methionine synthase II (ZP_00093248.1| COG0620: Methionine synthase II (cobalamin-independent) [Novosphingobium aromaticivorans]; CAF20466.1|; High confidence in function and specificity; hypothetical protein 247071..248258 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174662 YP_001220925.1 CDS metC NC_009480.1 248261 249622 D O-acetylhomoserine (Thiol)-lyase (EC 2.4.1.49) (Homocysteine synthase) (ZP_00228435.1| COG2873: O-acetylhomoserine sulfhydrylase [Kineococcus radiotolerans SRS30216]; ZP_00293095.1| COG2873: O-acetylhomoserine sulfhydrylase [Thermobifida fusca]). Transforms O-acetylhomoserine into homocysteine. pfam01053,Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme.; High confidence in function and specificity; O-acetylhomoserine (thiol)-lyase 248261..249622 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174727 YP_001220926.1 CDS CMM_0186 NC_009480.1 249625 250932 D putative oxidoreductase/monooxygenase (ZP_00228434.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_693700.1| thermophilic desulfurizing enzyme [Oceanobacillus iheyensis HTE831]; AAK63173.1| thiophene oxidizing enzyme [Tsukamurella wratislaviensis]).; Specificity unclear; putative oxidoreductase/monooxygenase 249625..250932 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174514 YP_001220927.1 CDS CMM_0187 NC_009480.1 250962 251618 R putative tetR-family transcriptional regulator (NP_824466.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_960670.1| hypothetical protein MAP1736 [Mycobacterium avium subsp. paratuberculosis str. k10]). InterPro: Bacterial regulatory proteins TetR family pfam00440,TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator complement(250962..251618) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174866 YP_001220928.1 CDS CMM_0188 NC_009480.1 251762 253300 D putative multi-drug efflux MFS permease (ZP_00226170.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_739141.1| putative lincomycin-resistance protein [Corynebacterium efficiens YS-314]). pfam00083,Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters efflux_EmrB: drug resistance transport; Specificity unclear; putative multi-drug efflux MFS permease 251762..253300 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174706 YP_001220929.1 CDS CMM_0189 NC_009480.1 253394 254248 D putative hydrolase (ZP_00191747.2| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Kineococcus radiotolerans SRS30216]; NP_624748.1| putative hydrolase [Streptomyces coelicolor A3(2)]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase 253394..254248 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174636 YP_001220930.1 CDS CMM_0190 NC_009480.1 254241 254825 D putative transcriptional regulator, TetR family (ZP_00191859.2| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_624749.1| putative tetR family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 254241..254825 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174460 YP_001220931.1 CDS CMM_0191 NC_009480.1 254831 255229 D Hypothetical protein; hypothetical protein 254831..255229 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174692 YP_001220932.1 CDS CMM_0192 NC_009480.1 255226 255621 R putative membrane protein weak similarity to: pfam04235, DUF418, Protein of unknown function (DUF418). Probable integral membrane protein.; Hypothetical protein; hypothetical protein complement(255226..255621) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174538 YP_001220933.1 CDS CMM_0193 NC_009480.1 255632 256381 R putative transcriptional regulator, TetR family (ZP_00126009.1| COG1309: Transcriptional regulator [Pseudomonas syringae pv. syringae B728a]; ZP_00192174.3| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator complement(255632..256381) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174490 YP_001220934.1 CDS CMM_0194 NC_009480.1 256493 257581 D putative oxidoreductase (NP_579646.1| putative dehydrogenase [Pyrococcus furiosus DSM 3638]; NP_103783.1| NADH-dependent dyhydrogenase [Mesorhizobium loti MAFF303099]). pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD.; Function unclear; putative oxidoreductase 256493..257581 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174402 YP_001220935.1 CDS CMM_0195 NC_009480.1 257578 258390 D hypothetical protein 257578..258390 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174388 YP_001220936.1 CDS CMM_0196 NC_009480.1 258445 259767 D putative sugar ABC transporter, binding protein (P_627687.1| putative secreted sugar-binding protein [Streptomyces coelicolor A3(2)]; YP_014349.1| ABC transporter, substrate-binding protein [Listeria monocytogenes str. 4b F2365]). pfam01547, SBP_bac_1,Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1; Specificity unclear; putative sugar ABC transporter binding protein 258445..259767 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174305 YP_001220937.1 CDS CMM_0197 NC_009480.1 259819 260805 D putative sugar ABC transporter, permease component (NP_627686.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]; NP_346128.1| ABC transporter, permease protein [Streptococcus pneumoniae TIGR4]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 259819..260805 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174482 YP_001220938.1 CDS CMM_0198 NC_009480.1 260802 261683 D putative sugar ABC transporter, permease component (NP_627685.1| putative sugar-permease [Streptomyces coelicolor A3(2)]; ZP_00192766.2| COG0395: ABC-type sugar transport system, permease component [Mesorhizobium sp. BNC1]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 260802..261683 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174192 YP_001220939.1 CDS CMM_0199 NC_009480.1 261760 262104 R hypothetical protein (CAF18736.1| hypothetical protein [Corynebacterium glutamicum ATCC 13032]; NP_898810.1| hypothetical protein PBD2.195 [Rhodococcus erythropolis]).; hypothetical protein complement(261760..262104) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174259 YP_001220940.1 CDS CMM_0200 NC_009480.1 262107 262565 R hypothetical protein (CAF18735.1| hypothetical protein [Corynebacterium glutamicum ATCC 13032]; NP_898809.1| hypothetical protein PBD2.194 [Rhodococcus erythropolis]).; hypothetical protein complement(262107..262565) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175119 YP_001220941.1 CDS CMM_0201 NC_009480.1 262610 264466 R putative glycosyl hydrolase, family 2 (NP_631552.1| putative hydrolase [Streptomyces coelicolor A3(2)]; ZP_00226612.1| COG3250: Beta-galactosidase/beta-glucuronidase [Kineococcus radiotolerans SRS30216]). pfam02837, Glyco_hydro_2_N, Glycosyl hydrolases family 2,sugar binding domain. pfam00703, Glyco_hydro_2, Glycosyl hydrolases family 2, immunoglobulin-like beta-sandwich domain. pfam02836, Glyco_hydro_2_C, Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.; Specificity unclear; glycoside hydrolase family protein complement(262610..264466) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174227 YP_001220942.1 CDS CMM_0202 NC_009480.1 264565 265752 R putative dehydrogenase/oxidoreductase (ZP_00226130.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_534841.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]). pfam01408, GFO_IDH_MocA,Oxidoreductase family, NAD-binding Rossmann fold. pfam02894, GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain.; Specificity unclear; putative dehydrogenase/oxidoreductase complement(264565..265752) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174094 YP_001220943.1 CDS CMM_0203 NC_009480.1 265809 268430 R putative multidrug efflux MFS permease (NP_627382.1| putative membrane transport protein [Streptomyces coelicolor A3(2)]; YP_044552.1| putative transport protein [Staphylococcus aureus subsp. aureus MSSA476]). pfam00529, HlyD, HlyD family secretion protein. actII: Transport protein; Function unclear; RND superfamily drug exporter complement(265809..268430) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174116 YP_001220944.1 CDS CMM_0204 NC_009480.1 268492 269082 D putative transcriptional regulator,TetR-family (NP_626528.1| putative TetR-family transcriptional regulator. [Streptomyces coelicolor A3(2)]; NP_350067.1| Transcriptional regulator, AcrR family [Clostridium acetobutylicum ATCC 824]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family; Specificity unclear; TetR family transcriptional regulator 268492..269082 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174033 YP_001220945.1 CDS CMM_0205 NC_009480.1 269099 270904 R putative membrane protein (CAF20404.1| putative membrane protein [Corynebacterium glutamicum ATCC 13032]). weak (N-terminal similarities) to serine proteases (Subtilisin subfamily).; Function unclear; hypothetical protein complement(269099..270904) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174044 YP_001220946.1 CDS CMM_0206 NC_009480.1 271019 271876 R converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase complement(271019..271876) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174011 YP_001220947.1 CDS CMM_0207 NC_009480.1 272021 272632 R conserved hypothetical protein (NP_624907.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00296064.1| COG0655: Multimeric flavodoxin WrbA [Methanosarcina barkeri str. fusaro]; NP_882980.1| NADPH-dependent FMN reductase [Bordetella parapertussis 12822]).; Function unclear; hypothetical protein complement(272021..272632) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173982 YP_001220948.1 CDS CMM_0208 NC_009480.1 272795 273652 D putative membrane-associated phospholipid phosphatase 272795..273652 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173965 YP_001220949.1 CDS CMM_0209 NC_009480.1 273681 273920 D Hypothetical protein; hypothetical protein 273681..273920 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173957 YP_001220950.1 CDS CMM_0210 NC_009480.1 273960 274382 D putative protein chain release factor B(NP_875617.1| Protein chain release factor B [Prochlorococcus marinus subsp. marinus str. CCMP1375]; ZP_00225589.1| COG1186: Protein chain release factor B [Kineococcus radiotolerans SRS30216]). pfam00472, RF-1,Peptidyl-tRNA hydrolase domain. This domain is found in peptide chain release factors such as RF-1 and RF-2, and a number of smaller proteins of unknown function. This domain contains the peptidyl-tRNA hydrolase activity. InterPro: Class I peptide chain release factor prfB: peptide chain release factor 2; Family membership; hypothetical protein 273960..274382 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173880 YP_001220951.1 CDS CMM_0211 NC_009480.1 274410 275459 R putative monooxygenase (ZP_00225458.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_534605.1| monooxygenase [Agrobacterium tumefaciens str. C58 (U. Washington)]). pfam00296,Bac_luciferase, Luciferase-like monooxygenase.; Function unclear; putative monooxygenase complement(274410..275459) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173825 YP_001220952.1 CDS CMM_0212 NC_009480.1 275539 275694 R conserved hypothetical protein, putative antitoxin (ZP_00204491.1| COG2161: Antitoxin of toxin-antitoxin stability system [Actinobacillus pleuropneumoniae serovar 1 str. 4074]; ZP_00177056.1| COG2161: Antitoxin of toxin-antitoxin stability system [Crocosphaera watsonii WH 8501]). pfam02604, DUF172, Uncharacterized ACR, COG2161.; hypothetical protein complement(275539..275694) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173912 YP_001220953.1 CDS CMM_0213 NC_009480.1 275764 276108 D conserved hypothetical protein (ZP_00018531.1| hypothetical protein [Chloroflexus aurantiacus]; ZP_00227133.1| COG4898: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein 275764..276108 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173783 YP_001220954.1 CDS CMM_0214 NC_009480.1 276105 276335 R conserved hypothetical protein (CAF21348.1| hypothetical protein predicted by Glimmer/Critica [Corynebacterium glutamicum ATCC 13032]; NP_828735.1| hypothetical protein [Streptomyces avermitilis MA-4680]).; hypothetical protein complement(276105..276335) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173767 YP_001220955.1 CDS CMM_0215 NC_009480.1 276332 276907 R putative transcriptional regulator, TetR family (NP_624661.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_624835.1| putative TetR family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family; Specificity unclear; TetR family transcriptional regulator complement(276332..276907) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173669 YP_001220956.1 CDS CMM_0216 NC_009480.1 277004 278119 D putative Zn-dependant oxidoreductase (XP_387934.1| hypothetical protein FG07758.1 [Gibberella zeae PH-1]; XP_405167.1| hypothetical protein AN1030.2 [Aspergillus nidulans FGSC A4]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily; Function unclear; putative Zn-dependent oxidoreductase 277004..278119 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173748 YP_001220957.1 CDS CMM_0217 NC_009480.1 278116 278919 R hypothetical protein (NP_898693.1| hypothetical protein PBD2.078 [Rhodococcus erythropolis]).; hypothetical protein complement(278116..278919) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173691 YP_001220958.1 CDS CMM_0218 NC_009480.1 278916 279569 R hypothetical protein (ZP_00657923.1| hypothetical protein NocaDRAFT_1855 [Nocardioides sp. JS614]); hypothetical protein complement(278916..279569) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173701 YP_001220959.1 CDS CMM_0219 NC_009480.1 279717 280016 D putative sulfurtransferase (NP_266940.1| hypothetical protein L193291 [Lactococcus lactis subsp. lactis Il1403]; NP_601905.1| rhodanese-related sulfurtransferase [Corynebacterium glutamicum ATCC 13032]). pfam00581, Rhodanese, Rhodanese-like domain. InterPro: Rhodanese/cdc25 fold; Function unclear; hypothetical protein 279717..280016 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173648 YP_001220960.1 CDS CMM_0220 NC_009480.1 280058 280642 D conserved hypothetical protein (ZP_00228399.1| COG4430: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; ZP_00274169.1| COG4430: Uncharacterized protein conserved in bacteria [Ralstonia metallidurans CH34]).; hypothetical protein 280058..280642 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173574 YP_001220961.1 CDS CMM_0221 NC_009480.1 280668 280982 R putative multidrug resistance membrane protein (ZP_00293737.1| COG2076: Membrane transporters of cations and cationic drugs [Thermobifida fusca]; AAL07365.1| putative small multidrug resistance protein [Stenotrophomonas maltophilia]). pfam00893,Multi_Drug_Res, Small Multidrug Resistance protein. This family is the Small Multidrug Resistance (SMR) family.; Specificity unclear; putative multidrug resistance membrane protein complement(280668..280982) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173599 YP_001220962.1 CDS CMM_0222 NC_009480.1 280982 281377 R putative multidrug resistance membrane protein (ZP_00293737.1| COG2076: Membrane transporters of cations and cationic drugs [Thermobifida fusca]; ZP_00173962.2| COG2076: Membrane transporters of cations and cationic drugs [Methylobacillus flagellatus KT]). pfam00893,Multi_Drug_Res, Small Multidrug Resistance protein. This family is the Small Multidrug Resistance (SMR) family. Several members have been shown to export a range of toxins, including ethidium bromide and quaternary ammonium compounds, through coupling with proton influx. InterPro: Integral membrane protein DUF7; Function unclear; putative multidrug resistance membrane protein complement(280982..281377) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173621 YP_001220963.1 CDS CMM_0223 NC_009480.1 281510 282169 R putative phosphatase (NP_533751.1| haloacid dehalogenase-like hydrolase [Agrobacterium tumefaciens str. C58]; ZP_00267448.1| COG0637: Predicted phosphatase/phosphohexomutase [Pseudomonas fluorescens PfO-1]; NP_827006.1| putative hydrolase [Streptomyces avermitilis MA-4680]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. TIGR00099: conserved hypothetical prote; Function unclear; putative phosphatase complement(281510..282169) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173568 YP_001220964.1 CDS CMM_0224 NC_009480.1 282255 283451 D putative glycosyl transferase (AAM70336.1| CalG1 [Micromonospora echinospora]; BAD08357.1| glycosyltransferase [Streptomyces halstedii]). pfam03033,Glyco_transf_28, Glycosyltransferase family 28 N-terminal domain. This N-terminal domain contains the acceptor binding site and likely membrane association site. pfam04101, Glyco_tran_28_C, Glycosyltransferase family 28 C-terminal domain.; Specificity unclear; putative glycosyl transferase 282255..283451 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174849 YP_001220965.1 CDS CMM_0225 NC_009480.1 283730 284890 D putative sarcosine oxidase (ZP_00227998.1| COG0665: Glycine/D-amino acid oxidases (deaminating) [Kineococcus radiotolerans SRS30216]; Q827H4|MSOX_STRAW Monomeric sarcosine oxidase (MSOX)). pfam01266, DAO, FAD dependent oxidoreductase.; Specificity unclear; putative sarcosine oxidase 283730..284890 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173549 YP_001220966.1 CDS CMM_0226 NC_009480.1 284921 285598 R hypothetical protein complement(284921..285598) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173506 YP_001220967.1 CDS CMM_0227 NC_009480.1 285732 286691 R putative acetyl xylan esterase (NP_822477.1| putative cephalosporin C deacetylase [Streptomyces avermitilis MA-4680]; NP_107393.1| acetyl xylan esterase [Mesorhizobium loti MAFF303099]). , pfam05448, AXE1,Acetyl xylan esterase (AXE1).; Specificity unclear; putative acetyl xylan esterase complement(285732..286691) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173527 YP_001220968.1 CDS CMM_0228 NC_009480.1 286773 287369 R putative transcriptional regulator, TetR family (NP_822813.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; CAB07159.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)[Mycobacterium tuberculosis H37Rv]). pfam00440,TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family; Specificity unclear; TetR family transcriptional regulator complement(286773..287369) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173489 YP_001220969.1 CDS CMM_0229 NC_009480.1 287456 289510 R putative acyl esterase (NP_826040.1| hypothetical protein SAV4863 [Streptomyces avermitilis MA-4680]; NP_105843.1|; Function unclear; putative acyl esterase complement(287456..289510) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173461 YP_001220970.1 CDS CMM_0230 NC_009480.1 289507 291240 R putative peptide ABC transporter, ATP-binding protein (NP_790103.1| peptide ABC transporter, ATP-binding protein [Pseudomonas syringae pv. tomato str. DC3000]; NP_415350.1| putative ATP-binding component of a transport system; putative oligopeptide transport protein (ABC superfamily, atp_bind) [Escherichia coli K12]). cd00267,ABC_ATPase, ABC (ATP-binding cassette) transporter nucleotide-binding domain (twice).; Specificity unclear; putative peptide ABC transporter ATP-binding protein complement(289507..291240) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173433 YP_001220971.1 CDS CMM_0231 NC_009480.1 291237 292118 R putative peptide ABC transporter, permease component (CAG20639.1| hypothetical ABC transporter permease [Photobacterium profundum]; NP_846941.1| oligopeptide ABC transporter, oligopeptide-binding protein [Bacillus anthracis str. Ames]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity; putative peptide ABC transporter permease complement(291237..292118) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173387 YP_001220972.1 CDS CMM_0232 NC_009480.1 292115 293134 R putative peptide ABC transporter, permease component (CAG20638.1| hypothetical ABC transporter,permease protein [Photobacterium profundum]; NP_085756.1| dipeptide transport system permease protein [Mesorhizobium loti MAFF303099]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative peptide ABC transporter permease complement(292115..293134) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173442 YP_001220973.1 CDS CMM_0233 NC_009480.1 293131 294786 R putative peptide ABC transporter, substrate-binding protein (CAG20637.1| hypothetical ABC transporter,periplasmic solute-binding protein, family 5 [Photobacterium profundum]; NP_357196.1| AGR_L_2824p [Agrobacterium tumefaciens str. C58]). pfam00496,SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative peptide ABC transporter substrate-binding protein complement(293131..294786) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173326 YP_001220974.1 CDS CMM_0234 NC_009480.1 294887 295393 R hypothetical protein complement(294887..295393) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173380 YP_001220975.1 CDS CMM_0235 NC_009480.1 295483 296382 R hypothetical protein complement(295483..296382) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173311 YP_001220976.1 CDS CMM_0236 NC_009480.1 296480 298468 R conserved membrane protein, putative amino acid permease, APC family (NP_825946.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00110752.1| COG0531: Amino acid transporters [Nostoc punctiforme]).; Conserved hypothetical protein; hypothetical protein complement(296480..298468) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173406 YP_001220977.1 CDS CMM_0237 NC_009480.1 298681 299049 R hypothetical protein complement(298681..299049) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173257 YP_001220978.1 CDS CMM_0238 NC_009480.1 299132 300355 R putative efflux MFS permease (NP_827094.1| putative bicyclomycin resistance protein [Streptomyces avermitilis MA-4680]; NP_830072.1| Bicyclomycin resistance protein [Bacillus cereus ATCC 14579]). pfam00083, Sugar_tr, Sugar (and other) transporter. TIGRFAM (TIGR00710): drug resistance transporter; Specificity unclear; putative bicyclomycin efflux MFS permease complement(299132..300355) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173338 YP_001220979.1 CDS CMM_0239 NC_009480.1 300554 300775 D hypothetical protein 300554..300775 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173267 YP_001220980.1 CDS CMM_0240 NC_009480.1 300958 301788 D putative short-chain alcohol dehydrogenase (ZP_00226165.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; ZP_00193775.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Mesorhizobium sp. BNC1]). pfam00106,adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short-chain alcohol dehydrogenase 300958..301788 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173293 YP_001220981.1 CDS CMM_0241 NC_009480.1 301826 302098 R Hypothetical protein; hypothetical protein complement(301826..302098) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173240 YP_001220982.1 CDS ogtA NC_009480.1 302169 302795 R Putative methylated-DNA-protein-cysteine methyltransferase (O-6-methylguanine-DNA-alkyltransferase) (ZP_00228907.1| COG0350: Methylated DNA-protein cysteine methyltransferase [Kineococcus radiotolerans SRS30216]; NP_602199.1| methylated DNA-protein cysteine methyltransferase [Corynebacterium glutamicum ATCC 13032]). pfam02870, Methyltransf_1N, 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain. pfam01035, Methyltransf_1, 6-O-methylguanine DNA methyltransferase, DNA binding domain.; Family membership; 6-O-methylguanine DNA methyltransferase complement(302169..302795) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173191 YP_001220983.1 CDS sigY NC_009480.1 302792 303322 R DNA-directed RNA polymerase specialized sigma subunit, ECF family (ZP_00228908.1| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Kineococcus radiotolerans SRS30216]; ZP_00293287.1| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Thermobifida fusca]). pfam04542,Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. pfam04545,Sigma70_r4, Sigma-70, region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.; Specificity unclear; hypothetical protein complement(302792..303322) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175121 YP_001220984.1 CDS CMM_0244 NC_009480.1 303648 304385 D putative two-component system response regulator (NP_825375.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]; NP_628202.1| putative two component system response regulator [Streptomyces coelicolor A3(2)]). pfam00072,Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. InterPro: Response regulator receiver domain; Function unclear; putative two-component system response regulator 303648..304385 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175919 YP_001220985.1 CDS CMM_0245 NC_009480.1 304664 305953 D hypothetical protein, , only weak N-terminal similarities to RTX toxins.; hypothetical protein 304664..305953 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173208 YP_001220986.1 CDS CMM_0246 NC_009480.1 306397 310155 D hypothetical protein 306397..310155 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173220 YP_001220987.1 CDS CMM_0247 NC_009480.1 310377 311591 D putative oxidoreductase/dehydrogenase (NP_823001.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]; ZP_00226131.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]). pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. pfam02894,GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain. InterPro: Oxidoreductase C-terminal redox_disulf_1: redox-active disulfide; Function unclear; putative oxidoreductase/dehydrogenase 310377..311591 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173126 YP_001220988.1 CDS CMM_0248 NC_009480.1 311642 312358 D conserved membrane protein (NP_625282.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; NP_823511.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; Conserved hypothetical protein; hypothetical protein 311642..312358 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173177 YP_001220989.1 CDS CMM_0249 NC_009480.1 312537 313244 D conserved hypothetical protein (NP_823510.1| hypothetical protein SAV2334 [Streptomyces avermitilis MA-4680]; ZP_00171355.2| COG4549: Uncharacterized protein conserved in bacteria [Ralstonia eutropha JMP134]). Mtu_fam_11: Mycobacterium tuberculosis p; hypothetical protein 312537..313244 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173108 YP_001220990.1 CDS CMM_0250 NC_009480.1 313241 314725 D conserved membrane protein (ZP_00126878.2| COG3182: Uncharacterized iron-regulated membrane protein [Pseudomonas syringae pv. syringae B728a]; ZP_00293139.1| COG3182: Uncharacterized iron-regulated membrane protein [Thermobifida fusca]; YP_049875.1| putative iron-regulated membrane protein [Erwinia carotovora subsp. atroseptica SCRI1043]). pfam03929, DUF337, Uncharacterized iron-regulated membrane protein (DUF337). bcl-2: Apoptosis regulator; Conserved hypothetical protein; hypothetical protein 313241..314725 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173161 YP_001220991.1 CDS CMM_0251 NC_009480.1 314775 315788 R putative LacI-family transcriptional regulator (ZP_00049013.1| COG1609: Transcriptional regulators [Magnetospirillum magnetotacticum]; NP_823745.1| putative LacI-family transcriptional regulator Streptomyces avermitilis MA-4680]). pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The LacI family of proteins consist of transcriptional regulators related to the lac repressor.; Specificity unclear; LacI family transcriptional regulator complement(314775..315788) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173052 YP_001220992.1 CDS CMM_0252 NC_009480.1 315851 316573 R conserved membrane protein (ZP_00239707.1| integral membrane protein [Bacillus cereus G9241]; NP_825757.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; Conserved hypothetical protein; hypothetical protein complement(315851..316573) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173145 YP_001220993.1 CDS CMM_0253 NC_009480.1 316624 317823 R putative glycosyl transferase (ZP_00329344.1| COG0438: Glycosyltransferase [Moorella thermoacetica ATCC 39073]; NP_294949.1| mannosyltransferase, putative [Deinococcus radiodurans R1]). pfam00534, Glycos_transf_1,Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates,including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP,ADP, GDP or CMP linked sugars.; Function unclear; hypothetical protein complement(316624..317823) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173067 YP_001220994.1 CDS CMM_0254 NC_009480.1 317976 318227 R hypothetical protein (NP_821697.1| hypothetical protein SAV522 [Streptomyces avermitilis MA-4680]; NP_436996.1| HYPOTHETICAL PROTEIN SMb20474 [Sinorhizobium meliloti 1021]).; hypothetical protein complement(317976..318227) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173094 YP_001220995.1 CDS CMM_0255 NC_009480.1 318363 319832 D putative efflux MFS permease (ZP_00190381.2| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_628802.1| putative transmembrane efflux protein [Streptomyces coelicolor A3(2)]). pfam00083, Sugar_tr, Sugar (and other) transporter. efflux_EmrB: drug resistance transport; Specificity unclear; putative MFS permease 318363..319832 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173018 YP_001220996.1 CDS CMM_0256 NC_009480.1 320052 320687 R conserved hypothetical protein (ZP_00280805.1| COG2907: Predicted NAD/FAD-binding protein [Burkholderia fungorum LB400]; ZP_00150213.1| COG2907: Predicted NAD/FAD-binding protein [Dechloromonas aromatica RCB]).; Function unclear; hypothetical protein complement(320052..320687) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173045 YP_001220997.1 CDS CMM_0257 NC_009480.1 320698 321345 R putative transcriptional regulator, MerR family (NP_629684.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_828502.1| putative transcriptional regulator [Streptomyces avermitilis MA-4680]). smart00422, HTH_MERR, helix_turn_helix, mercury resistance.; Specificity unclear; MerR family transcriptional regulator complement(320698..321345) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173002 YP_001220998.1 CDS CMM_0258 NC_009480.1 321541 322134 R conserved hypothetical protein (NP_901178.1| probable transmembrane protein [Chromobacterium violaceum ATCC 12472]; NP_623732.1| conserved hypothetical protein [Thermoanaerobacter tengcongensis]).; hypothetical protein complement(321541..322134) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173037 YP_001220999.1 CDS crcB1 NC_009480.1 322313 322837 D putative membrane protein involved in chromosome condensation (AAK73171.1| putative CrcB-like protein [Brevibacterium sp. HCU]; AAL42476.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]) pfam02537, CRCB, CrcB-like protein. CRCB is a putative integral membrane protein possibly involved in chromosome condensation. crcB: crcB protein; Function unclear; putative membrane protein involved in chromosome condensation 322313..322837 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172950 YP_001221000.1 CDS crcB2 NC_009480.1 322834 323214 D putative membrane protein involved in chromosome condensation (Q9FC37|CRB2_STRCO Protein crcB homolog 2; ZP_00043418.1| COG0239: Integral membrane protein possibly involved in chromosome condensation [Magnetococcus sp. MC-1]). pfam02537, CRCB, CrcB-like protein. CRCB is a putative integral membrane protein possibly involved in chromosome condensation. crcB: crcB protein; Function unclear; putative membrane protein involved in chromosome condensation 322834..323214 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173467 YP_001221001.1 CDS CMM_0261 NC_009480.1 323211 323687 D putative acetyltransferase (NP_294404.1| hypothetical protein [Deinococcus radiodurans]; ZP_00186452.1| COG1246: N-acetylglutamate synthase and related acetyltransferases [Rubrobacter xylanophilus DSM 9941]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 323211..323687 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172975 YP_001221002.1 CDS CMM_0262 NC_009480.1 323697 324284 D putative NTP pyrophosphohydrolases (ZP_00188287.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Rubrobacter xylanophilus DSM 9941]; ZP_00330170.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Moorella thermoacetica ATCC 39073]). pfam00293, NUDIX, NUDIX domain.; Function unclear; putative NTP pyrophosphohydrolases 323697..324284 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172966 YP_001221003.1 CDS ddlA NC_009480.1 324294 325301 R putative D-alanine-D-alanine ligase (ZP_00137683.2| COG1181: D-alanine-D-alanine ligase and related ATP-grasp enzymes [Pseudomonas aeruginosa UCBPP-PA14]; ZP_00212274.1| COG1181: D-alanine-D-alanine ligase and related ATP-grasp enzymes [Burkholderia cepacia R18194]). Cell wall formation (By similarity). pfam01820,Dala_Dala_ligas, D-ala D-ala ligase. InterPro: D-alanine--D-alanine ligase.; High confidence in function and specificity; putative D-alanine--D-alanine ligase complement(324294..325301) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173907 YP_001221004.1 CDS CMM_0264 NC_009480.1 325348 326058 R conserved hypothetical protein (NP_630443.1| hypothetical protein SC3A7.19 [Streptomyces coelicolor A3(2)]; ZP_00034039.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Burkholderia fungorum]). pfam00561, Abhydrolase_1,alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; hypothetical protein complement(325348..326058) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174994 YP_001221005.1 CDS CMM_0265 NC_009480.1 326061 326615 R conserved hypothetical protein (NP_631701.1| putative secreted protein [Streptomyces coelicolor A3(2)]; ZP_00049640.1| COG0262: Dihydrofolate reductase [Magnetospirillum magnetotacticum]). pfam01872, RibD_C,RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis.; Family membership; hypothetical protein complement(326061..326615) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172976 YP_001221006.1 CDS CMM_0266 NC_009480.1 326881 328224 D conserved membrane protein (NP_791711.1| membrane protein, putative [Pseudomonas syringae pv. tomato str. DC3000]; NP_901555.1| hypothetical protein CV1885 [Chromobacterium violaceum ATCC 12472]).; Conserved hypothetical protein; hypothetical protein 326881..328224 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175583 YP_001221007.1 CDS CMM_0267 NC_009480.1 328221 329078 D putative transcriptional regulator, RpiR family (NP_781945.1| transcriptional regulator, rpiR family [Clostridium tetani E88]; NP_519498.1| CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]). pfam01418,HTH_6, Helix-turn-helix domain, rpiR family. This domain contains a helix-turn-helix motif. The best characterised member of this family is RpiR, a regulator of the expression of rpiB gene. pfam01380, SIS, SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins.; Specificity unclear; RpiR family transcriptional regulator 328221..329078 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172923 YP_001221008.1 CDS CMM_0268 NC_009480.1 329139 330083 D putative hydroxyacid dehydrogenase (ZP_00127342.1| COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Pseudomonas syringae pv. syringae B728a]; YP_044837.1| putative 3-hydroxyisobutyrate dehydrogenase [Acinetobacter sp. ADP1]). pfam03446, NAD_binding_2, NAD binding domain of 6-phosphogluconate dehydrogenase.; Specificity unclear; putative hydroxyacid dehydrogenase 329139..330083 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173012 YP_001221009.1 CDS CMM_0269 NC_009480.1 330080 331660 D putative aldehyde dehydrogenase (ZP_00166104.1| COG1012: NAD-dependent aldehyde dehydrogenases [Ralstonia eutropha JMP134]; NP_791704.1| aldehyde dehydrogenase family protein [Pseudomonas syringae pv. tomato str. DC3000]). pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. InterPro: Aldehyde dehydrogenase family.; Specificity unclear; putative aldehyde dehydrogenase 330080..331660 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175506 YP_001221010.1 CDS CMM_0270 NC_009480.1 331874 333112 D putative sugar ABC transporter, substrate binding protein (ZP_00192200.3| COG1653: ABC-type sugar transport system, periplasmic component [Kineococcus radiotolerans SRS30216]; NP_625350.1| putative sugar transport sugar binding protein [Streptomyces coelicolor A3(2)]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1; Specificity unclear; putative sugar ABC transporter substrate binding protein 331874..333112 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173127 YP_001221011.1 CDS CMM_0271 NC_009480.1 333112 334101 D putative sugar ABC transporter, permease component (ZP_00226127.1| COG1175: ABC-type sugar transport systems,permease components [Kineococcus radiotolerans SRS30216]; NP_625351.1| putative sugar transport integral membrane protein [Streptomyces coelicolor A3(2)]). InterPro: Binding-protein-dependent transport systems inner membrane component; Specificity unclear; putative sugar ABC transporter permease 333112..334101 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175681 YP_001221012.1 CDS CMM_0272 NC_009480.1 334094 334969 D putative sugar ABC transporter, permease component (ZP_00226128.1| COG0395: ABC-type sugar transport system,permease component [Kineococcus radiotolerans SRS30216]; NP_625352.1| putative sugar transport integral membrane protein [Streptomyces coelicolor A3(2)]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component; Specificity unclear; putative sugar ABC transporter permease 334094..334969 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175281 YP_001221013.1 CDS CMM_0273 NC_009480.1 335052 335822 D conserved hypothetical protein (ZP_00226129.1| COG4813: Trehalose utilization protein [Kineococcus radiotolerans SRS30216]; NP_693487.1| hypothetical protein OB2566 [Oceanobacillus iheyensis HTE831]). pfam06283, DUF1037, Protein of unknown function (DUF1037). This family consists of several bacterial ThuA like proteins. The function of the family is unknown.; Function unclear; trehalose utilization-like protein 335052..335822 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173236 YP_001221014.1 CDS CMM_0274 NC_009480.1 335819 337048 D putative dehydrogenase (ZP_00226130.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_534841.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]). pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD. pfam02894, GFO_IDH_MocA_C, Oxidoreductase family,C-terminal alpha/beta domain.; Function unclear; putative dehydrogenase 335819..337048 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173176 YP_001221015.1 CDS CMM_0275 NC_009480.1 337069 338382 D transcriptional regulator, ROK family (ZP_00227613.1| COG1940: Transcriptional regulator/sugar kinase [Kineococcus radiotolerans SRS30216]; NP_623501.1| Transcriptional regulator [Thermoanaerobacter tengcongensis]). InterPro: ROK family ROK_glcA_fam: ROK family protein (puta; Specificity unclear; ROK family transcriptional regulator 337069..338382 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172931 YP_001221016.1 CDS CMM_0276 NC_009480.1 338379 339035 D conserved hypothetical protein, putative phosphatase (ZP_00163802.1| hypothetical protein Selo236801 [Synechococcus elongatus PCC 7942]; NP_945802.1| possible hydrolases/phosphatases [Rhodopseudomonas palustris CGA009]). pfam00702,Hydrolase, haloacid dehalogenase-like hydrolase. This family are structurally different from the alpha/ beta hydrolase family (pfam00561). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.; Family membership; hypothetical protein 338379..339035 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173529 YP_001221017.1 CDS CMM_0277 NC_009480.1 339073 340074 R Hypothetical protein; hypothetical protein complement(339073..340074) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173315 YP_001221018.1 CDS CMM_0278 NC_009480.1 340257 340847 D putative chorismate mutase (ZP_00041424.1| COG1605: Chorismate mutase [Xylella fastidiosa Ann-1]; ZP_00217335.1| COG1605: Chorismate mutase [Burkholderia cepacia R18194]). pfam01817, Chorismate_mut, Chorismate mutase. InterPro: Chorismate mutase; Family membership; putative chorismate mutase 340257..340847 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173673 YP_001221019.1 CDS CMM_0279 NC_009480.1 340959 341297 R conserved membrane protein (CAB02345.1| PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_825933.1| hypothetical protein SAV4756 [Streptomyces avermitilis MA-4680]). pfam02694,UPF0060, Uncharacterized BCR, YnfA/UPF0060 family.; Conserved hypothetical protein; hypothetical protein complement(340959..341297) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174944 YP_001221020.1 CDS CMM_0280 NC_009480.1 341356 341847 R conserved hypothetical protein (NP_828610.1| hypothetical protein SAV7434 [Streptomyces avermitilis MA-4680]; ZP_00225717.1| hypothetical protein Krad06004549 [Kineococcus radiotolerans SRS30216]).; hypothetical protein complement(341356..341847) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173443 YP_001221021.1 CDS CMM_0281 NC_009480.1 342105 342899 R putative acetyltransferase (NP_295640.1| hypothetical protein [Deinococcus radiodurans R1]; NP_822402.1| hypothetical protein SAV1227 [Streptomyces avermitilis MA-4680]; NP_935421.1| acetyltransferase [Vibrio vulnificus YJ016]). weak similarities to: COG3153,COG3153, Predicted acetyltransferase [General function prediction only]; pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. nadC: nicotinate-nucleotide pyrophosphor; putative acetyltransferase complement(342105..342899) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173095 YP_001221022.1 CDS CMM_0282 NC_009480.1 342905 345463 R conserved hypothetical protein (ZP_00294435.1| hypothetical protein Tfus02000641 [Thermobifida fusca]; NP_624665.1| putative large secreted protein [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(342905..345463) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173346 YP_001221023.1 CDS CMM_0283 NC_009480.1 345561 346151 D putative adenylate kinase (NP_599567.1| putative adenylate kinase [Corynebacterium glutamicum ATCC 13032]; NP_293926.1| hypothetical protein [Deinococcus radiodurans R1]).; Function unclear; putative adenylate kinase 345561..346151 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173646 YP_001221024.1 CDS CMM_0284 NC_009480.1 346118 346705 R hypothetical protein complement(346118..346705) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173552 YP_001221025.1 CDS CMM_0285 NC_009480.1 346723 347499 R putative permease, DMT family (ZP_00198666.1| COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily [Kineococcus radiotolerans SRS30216]; NP_629665.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam00892, DUF6,Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function.; Specificity unclear; permease DMT family complement(346723..347499) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173929 YP_001221026.1 CDS CMM_0286 NC_009480.1 347748 348374 D putative transcriptional regulator, TetR family (NP_629666.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_940577.1| Putative TetR-family transcriptional regulator [Corynebacterium diphtheriae]). InterPro: Bacterial regulatory proteins TetR family; Specificity unclear; TetR family transcriptional regulator 347748..348374 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175394 YP_001221027.1 CDS CMM_0287 NC_009480.1 348371 348868 D putative diadenosine tetraphosphate (Ap4A) hydrolase, Hit family (NP_539734.1| BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE (ASYMMETRICAL) [Brucella melitensis]; NP_102422.1| probable Hit-like protein involved in cell-cycle regulation [Mesorhizobium loti MAFF303099]). cd01277, HINT_subgroup, HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides.; Specificity unclear; diadenosine tetraphosphate hydrolase 348371..348868 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173476 YP_001221028.1 CDS CMM_0288 NC_009480.1 348940 349608 D putative oxidoreductase/dehydrogenase (NP_823521.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]; CAC14507.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative oxidoreductase 348940..349608 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174709 YP_001221029.1 CDS CMM_0289 NC_009480.1 349694 350386 R conserved secreted protein (ZP_00227777.1| COG2353: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_939578.1| Putative secreted protein [Corynebacterium diphtheriae]). pfam04264, YceI,YceI like family. E. coli YceI is a base-induced periplasmic protein. Its function has not yet been characterised.; Conserved hypothetical protein; hypothetical protein complement(349694..350386) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173491 YP_001221030.1 CDS sigL NC_009480.1 350578 351084 D RNA polymerase sigma factor, ECF-subfamily (NP_215249.1| sigL [Mycobacterium tuberculosis H37Rv]; ZP_00225475.1| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Kineococcus radiotolerans SRS30216]). pfam04542, Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. pfam04545, Sigma70_r4, Sigma-70,region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.; Specificity unclear; RNA polymerase ECF-subfamily sigma factor 350578..351084 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173374 YP_001221031.1 CDS CMM_0291 NC_009480.1 351081 351872 D conserved membrane protein, putative anti-sigma factor (NP_215250.1| hypothetical protein Rv0736 [Mycobacterium tuberculosis H37Rv]; NP_826301.1| putative membrane protein [Streptomyces avermitilis MA-4680]). similarity to anti-sigma factors (COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]); Conserved hypothetical protein; hypothetical protein 351081..351872 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175170 YP_001221032.1 CDS CMM_0292 NC_009480.1 352171 352761 R hypothetical protein (ZP_00410568.1| hypothetical protein ArthDRAFT_3888 [Arthrobacter sp. FB24]).; hypothetical protein complement(352171..352761) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173750 YP_001221033.1 CDS CMM_0293 NC_009480.1 352835 354202 D putative MFS permease (ZP_00098466.1| COG0477: Permeases of the major facilitator superfamily [Desulfitobacterium hafniense]; NP_834739.1| Macrolide-efflux protein [Bacillus cereus ATCC 14579]). pfam05977,DUF894, Bacterial protein of unknown function (DUF894). This family consists of several bacterial proteins, many of which are annotated as putative transmembrane transport proteins.; Specificity unclear; putative MFS permease 352835..354202 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173707 YP_001221034.1 CDS CMM_0294 NC_009480.1 354199 354702 R conserved hypothetical protein (NP_294991.1| hypothetical protein [Deinococcus radiodurans R1]; NP_827164.1| hypothetical protein SAV5987 [Streptomyces avermitilis MA-4680]). PPR: pentatricopeptide repeat domain; Family membership; hypothetical protein complement(354199..354702) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174184 YP_001221035.1 CDS CMM_0295 NC_009480.1 354731 355741 R HTH-type transcriptional repressor, LacI family (NP_823290.1| putative transcriptional regulator [Streptomyces avermitilis MA-4680]; ZP_00330608.1| COG1609: Transcriptional regulators [Moorella thermoacetica ATCC 39073]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators.; Specificity unclear; LacI family transcriptional regulator complement(354731..355741) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174309 YP_001221036.1 CDS CMM_0296 NC_009480.1 355969 357261 D putative sugar ABC transporter, substrate-binding protein (ZP_00121433.1| COG1653: ABC-type sugar transport system, periplasmic component [Bifidobacterium longum DJO10A]; NP_826156.1| putative sugar transporter solute-binding protein [Streptomyces avermitilis MA-4680]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter substrate-binding protein 355969..357261 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175511 YP_001221037.1 CDS CMM_0297 NC_009480.1 357272 358297 D putative sugar ABC transporter, permease component (NP_826157.1| putative binding protein-dependent transporter [Streptomyces avermitilis MA-4680]; NP_533738.1| ABC transporter, membrane spanning protein [sugar] [Agrobacterium tumefaciens str. C58]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 357272..358297 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175586 YP_001221038.1 CDS CMM_0298 NC_009480.1 358294 359199 D putative sugar ABC transporter, permease component (NP_826158.1| putative binding protein-dependent transporter [Streptomyces avermitilis MA-4680]; NP_533737.1| ABC transporter, membrane spanning protein [sugar] [Agrobacterium tumefaciens str. C58]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; High confidence in function and specificity; putative sugar ABC transporter permease 358294..359199 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173955 YP_001221039.1 CDS bglX NC_009480.1 359196 361577 D putative beta-glycosidase, putative xylosidase (ZP_00226641.1| COG1472: Beta-glucosidase-related glycosidases [Kineococcus radiotolerans SRS30216]; JC7728 xylan 1,4-beta-xylosidase (EC 3.2.1.37) - Streptomyces thermoviolaceus). pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915,Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.; Specificity unclear; putative beta-glycosidase 359196..361577 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174387 YP_001221040.1 CDS CMM_0300 NC_009480.1 361717 362565 R putative nucleoside-diphosphate-sugar epimerase (ZP_00227284.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; NP_822058.1| hypothetical protein [Streptomyces avermitilis MA-4680]).; Function unclear; putative nucleoside-diphosphate-sugar epimerase complement(361717..362565) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173104 YP_001221041.1 CDS CMM_0301 NC_009480.1 362661 363410 D putative transcriptional regulator, TetR family (NP_822057.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; CAE53340.1| putative TetR-family transcitpional regulator [Actinoplanes teichomyceticus]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 362661..363410 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174376 YP_001221042.1 CDS CMM_0302 NC_009480.1 363450 364307 R putative transcriptional regulator, Cro/CI family (NP_625190.1| putative DNA-binding protein [Streptomyces coelicolor A3(2)]; NP_821830.1| putative DNA-binding protein [Streptomyces avermitilis MA-4680]). pfam01381,HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Function unclear; Cro/CI family transcriptional regulator complement(363450..364307) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174425 YP_001221043.1 CDS CMM_0303 NC_009480.1 364409 365089 D putative short chain dehydrogenase/oxidoreductase (ZP_00227716.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; NP_625189.1| putative short chain oxidoreductase. [Streptomyces coelicolor A3(2)]). pfam00106, adh_short,short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; short chain oxidoreductase 364409..365089 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174560 YP_001221044.1 CDS CMM_0304 NC_009480.1 365157 365555 D conserved hypothetical protein (NP_386041.1| CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti 1021]; NP_739257.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam05146, DUF704,Aha1 domain. The function of this presumed domain is unknown.; hypothetical protein 365157..365555 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174585 YP_001221045.1 CDS CMM_0305 NC_009480.1 365594 366160 D putative acetyltransferase (ZP_00227803.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Kineococcus radiotolerans SRS30216]; NP_600641.1| acetyltransferase [Corynebacterium glutamicum ATCC 13032]).; Function unclear; hypothetical protein 365594..366160 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173130 YP_001221046.1 CDS CMM_0306 NC_009480.1 366519 367412 D Region start changed from 366300 to 366519 (-219 bases); hypothetical protein 366519..367412 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175434 YP_001221047.1 CDS CMM_0307 NC_009480.1 367435 367848 R putative thiosulfate sulfurtransferase (ZP_00227801.1| COG0607: Rhodanese-related sulfurtransferase [Kineococcus radiotolerans SRS30216]; NP_625584.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). Catalyzes although with low efficiency the sulfur transfer reaction from thiosulfate to cyanide (By similarity). pfam00581,Rhodanese, Rhodanese-like domain. InterPro: Rhodanese/cdc25 fold; Function unclear; putative sulfurtransferase complement(367435..367848) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174749 YP_001221048.1 CDS CMM_0308 NC_009480.1 368106 369347 D conserved hypothetical protein (BAB98631.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032]; NP_695848.1| hypothetical protein BL0662 [Bifidobacterium longum NCC2705]).; hypothetical protein 368106..369347 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175081 YP_001221049.1 CDS CMM_0309 NC_009480.1 369387 369920 R conserved hypothetical protein (NP_627216.1| hypothetical protein SCE50.21 [Streptomyces coelicolor A3(2)]; ZP_00191774.2| COG0529: Adenylylsulfate kinase and related kinases [Kineococcus radiotolerans SRS30216]). weak similarity to: smart00382, AAA, ATPases associated with a variety of cellular activities; hypothetical protein complement(369387..369920) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175182 YP_001221050.1 CDS abfA1 NC_009480.1 370093 371634 D alpha-L-arabinofuranosidase (Arabinosidase) (ZP_00121523.2| COG3534: Alpha-L-arabinofuranosidase [Bifidobacterium longum DJO10A]; NP_626674.1| alpha-L-arabinofuranosidase [Streptomyces coelicolor A3(2)]). ,pfam03662, Glyco_hydro_79n, Glycosyl hydrolase family 79,N-terminal domain. , pfam06964, Alpha-L-AF_C, Alpha-L-arabinofuranosidase C-terminus.This catalyses the hydrolysis of nonreducing terminal alpha-L-arabinofuranosidic linkages in L-arabinose-containing polysaccharides.; High confidence in function and specificity; hypothetical protein 370093..371634 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175061 YP_001221051.1 CDS CMM_0311 NC_009480.1 371722 371940 R hypothetical protein (NP_626168.1| hypothetical hydrophilic protein [Streptomyces coelicolor A3(2)]; NP_845828.1| conserved hypothetical protein [Bacillus anthracis str. Ames]).; hypothetical protein complement(371722..371940) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175955 YP_001221052.1 CDS CMM_0312 NC_009480.1 372277 372867 R putative acetyltransferase (ZP_00184424.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Exiguobacterium sp. 255-15]; NP_626962.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(372277..372867) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175571 YP_001221053.1 CDS CMM_0313 NC_009480.1 372914 373255 R hypothetical protein (NP_825872.1| putative Lsr2-like protein [Streptomyces avermitilis MA-4680]; ZP_00293146.1| hypothetical protein Tfus02001333 [Thermobifida fusca]).; hypothetical protein complement(372914..373255) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175024 YP_001221054.1 CDS CMM_0314 NC_009480.1 373355 374428 D conserved hypothetical protein, putative GTPase (NP_962706.1| hypothetical protein MAP3772c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00173773.1| COG0523: Putative GTPases (G3E family) [Methylobacillus flagellatus KT]). pfam02492, cobW, Cobalamin synthesis protein/P47K.; hypothetical protein 373355..374428 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174025 YP_001221055.1 CDS CMM_0315 NC_009480.1 374511 375521 D putative thioredoxin reductase (ZP_00217649.1| COG0492: Thioredoxin reductase [Burkholderia cepacia R18194]; NP_639620.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]). pfam00070, Pyr_redox,Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Function unclear; putative thioredoxin reductase 374511..375521 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174473 YP_001221056.1 CDS clpY NC_009480.1 375588 377780 D putative ATP-dependant protease, ATPase subunit (ZP_00225929.1| COG0542: ATPases with chaperone activity,ATP-binding subunit [Kineococcus radiotolerans SRS30216]; YP_056693.1| ATP-dependent protease (Clp chaperone) [Propionibacterium acnes KPA171202]). pfam00004, AAA,ATPase family associated with various cellular activities (AAA) (twice). clpX: ATP-dependent Clp protease ATP; Function unclear; chaperone ATPase 375588..377780 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174291 YP_001221057.1 CDS agaA NC_009480.1 377847 380030 R alpha-galactosidase (Melibiase)(ZP_00226650.1| COG3345: Alpha-galactosidase [Kineococcus radiotolerans SRS30216]; AAD30994.2| alpha-galactosidase [Bifidobacterium adolescentis]). pfam02065, Melibiase,Melibiase.; High confidence in function and specificity; hypothetical protein complement(377847..380030) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175612 YP_001221058.1 CDS CMM_0318 NC_009480.1 380141 380620 D putative transcriptional regulator (only weak similarity, ZP_00199538.1| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_624573.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]).; Family membership; putative transcriptional regulator 380141..380620 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173131 YP_001221059.1 CDS CMM_0319 NC_009480.1 380682 381347 R conserved hypothetical protein (ZP_00199464.2| hypothetical protein Krad06000208 [Kineococcus radiotolerans SRS30216]; NP_216552.1| hypothetical protein Rv2036 [Mycobacterium tuberculosis H37Rv]; NP_630338.1| conserved hypothetical protein SCAH10.03 [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(380682..381347) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175308 YP_001221060.1 CDS CMM_0320 NC_009480.1 381414 381764 R hypothetical protein complement(381414..381764) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172964 YP_001221061.1 CDS CMM_0321 NC_009480.1 381880 382884 D putative oxidoreductase (ZP_00225711.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; ZP_00292358.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Thermobifida fusca]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.; Function unclear; putative oxidoreductase 381880..382884 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174716 YP_001221062.1 CDS CMM_0322 NC_009480.1 382892 384100 D putative dipeptidase (NP_826200.1| putative dipeptidase [Streptomyces avermitilis MA-4680]; ZP_00191103.2| COG2355: Zn-dependent dipeptidase,microsomal dipeptidase homolog [Kineococcus radiotolerans SRS30216]). pfam01244, Renal_dipeptase, Renal dipeptidase.; High confidence in function and specificity; putative dipeptidase 382892..384100 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173144 YP_001221063.1 CDS CMM_0323 NC_009480.1 384097 384960 D putative acetyltransferase, GnaT family (NP_629283.1| hypothetical protein [Streptomyces coelicolor A3(2)]; AAB84468.1| putative acetyl transferase [Bacillus subtilis]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Family membership; GNAT family acetyltransferase 384097..384960 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173115 YP_001221064.1 CDS CMM_0324 NC_009480.1 384894 386636 R putative ABC transporter (fused permease/ATPase) (NP_631729.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]; AAN77618.1| putative ABC transporter [Mycobacterium avium subsp. paratuberculosis]). putative exporter of siderophore/antibiotic.; High confidence in function and specificity; putative ABC transporter (fused permease/ATPase) complement(384894..386636) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174983 YP_001221065.1 CDS CMM_0325 NC_009480.1 386636 388456 R putative ABC transporter (fused permease/ATPase) (NP_631728.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]; ZP_00267801.1| COG1132: ABC-type multidrug transport system, ATPase and permease components [Rhodospirillum rubrum]). putative exporter of siderophore/antibiotic.; High confidence in function and specificity; putative ABC transporter (fused permease/ATPase) complement(386636..388456) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172932 YP_001221066.1 CDS CMM_0326 NC_009480.1 388453 389223 R putative methyltransferase (NP_631727.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_962672.1| hypothetical protein MAP3738c [Mycobacterium avium subsp. paratuberculosis str. k10]). PUTATIVELY INVOLVED IN METHYLATION OF SIDEROPHORE/ANTIBIOTIC.; Specificity unclear; hypothetical protein complement(388453..389223) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174014 YP_001221067.1 CDS CMM_0327 NC_009480.1 389220 390032 R putative thioesterase (NP_821582.1| putative thioesterase [Streptomyces avermitilis MA-4680]; S49055 thioesterase - Streptomyces fradiae (strain T59235)). pfam00975, Thioesterase, Thioesterase domain. Peptide synthetases are involved in the non-ribosomal synthesis of peptide antibiotics. Next to the operons encoding these enzymes, in almost all cases, are genes that encode proteins that have similarity to the type II fatty acid thioesterases of vertebrates.; High confidence in function and specificity; putative thioesterase complement(389220..390032) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174437 YP_001221068.1 CDS CMM_0328 NC_009480.1 390130 392058 R putative oxidoreductase/methylase (NP_631724.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_404400.1| conserved hypothetical protein [Yersinia pestis]; NP_631727.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). two domains: N-terminal (COG4693, PchG, Oxidoreductase (NAD-binding),involved in siderophore biosynthesis; pfam07414, YbtU,Yersiniabactin synthetase thiazolinyl reductase component YbtU. This family represents the thiazolinyl reductase component YbtU (approximately 350 residues long) of the bacterial four-protein yersiniabactin synthetase complex.). C-terminal putative methylase(COG2242, CobL,Precorrin-6B methylase 2,COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis; pfam00891,Methyltransf_2, O-methyltransferase. This family includes a range of O-methyltransferases. These enzymes utilise S-adenosyl methionine.). putatively involved in the modification of a siderophore/antibiotic.; Specificity unclear; putative oxidoreductase/methylase complement(390130..392058) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173269 YP_001221069.1 CDS CMM_0329 NC_009480.1 392055 393200 R putative dehydrogenase, iron-regulated protein (NP_631723.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_962677.1| hypothetical protein MAP3743 [Mycobacterium avium subsp. paratuberculosis str. k10]). putatively involved in the modification of a siderophore/antibiotic. weak similarity to: COG1748, LYS9,Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; pfam03435, Saccharop_dh,Saccharopine dehydrogenase.; Function unclear; putative dehydrogenase, iron-regulated protein complement(392055..393200) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174419 YP_001221070.1 CDS npsB NC_009480.1 393197 398776 R non-ribosomal peptide syntethase (NP_631722.1| putative non-ribosomal peptide synthase [Streptomyces coelicolor A3(2)]; NP_252915.1| pyochelin synthetase [Pseudomonas aeruginosa PA01]). putatively involved in the biosynthesis of a catecholate siderophore/antibiotic. pfam00668, Condensation, Condensation domain. pfam00501,AMP-binding, AMP-binding enzyme. pfam01209,Ubie_methyltran, ubiE/COQ5 methyltransferase family. pfam00550, PP-binding, Phosphopantetheine attachment site. pfam00975, Thioesterase, Thioesterase domain.; Specificity unclear; non-ribosomal peptide synthetase complement(393197..398776) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175282 YP_001221071.1 CDS npsA NC_009480.1 398773 405660 R non ribosomal peptide synthethase (NP_631721.1| putative non-ribosomal peptide synthase [Streptomyces coelicolor A3(2)]; NP_534178.1| non-ribosomal peptide synthetase [Agrobacterium tumefaciens str. C58]). putatively involved in the biosynthesis of a catecholate siderophore/antibiotic. two activation/conjugation domains. pfam00501, AMP-binding, AMP-binding enzyme (twice: Aa 609-1014, 1682-2079). pfam00668, Condensation,Condensation domain (twice: Aa 112-409, 1185-1475). pfam00550, PP-binding, Phosphopantetheine attachment site (thrice: Aa 13-76, 1099-1162, 2188-2246).; Specificity unclear; non-ribosomal peptide synthetase complement(398773..405660) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174409 YP_001221072.1 CDS CMM_0332 NC_009480.1 405761 407479 D putative organic acid CoA ligase (NP_631720.1| putative AMP-binding ligase [Streptomyces coelicolor A3(2)]; ZP_00059514.1| COG1021: Peptide arylation enzymes [Thermobifida fusca]). putatively involved in the biosynthesis of a catecholate siderophore/antibiotic. pfam00501, AMP-binding, AMP-binding enzyme.; Specificity unclear; hypothetical protein 405761..407479 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174131 YP_001221073.1 CDS CMM_0333 NC_009480.1 407472 408191 D putative 4-phosphopantetheinyl transferase (NP_337369.1| EntD-related protein [Mycobacterium tuberculosis CDC1551]; AAR92400.1| Sfp-type phosphopantetheinyl transferase [Saccharopolyspora erythraea]). pfam01648, ACPS, 4'-phosphopantetheinyl transferase superfamily.; Specificity unclear; 4'-phosphopantetheinyl transferase 407472..408191 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173961 YP_001221074.1 CDS CMM_0334 NC_009480.1 408202 409668 D putative anthranilate synthase (CAG20074.1| hypotetical anthranilate synthase [Photobacterium profundum]; NP_405477.1| putative salicylate synthetase [Yersinia pestis]). putatively involved in the synthesis of an aromatic acid (salicylate, isochorismate) for a catecholate siderophore/antibiotic. pfam00425,Chorismate_bind, chorismate binding enzyme. This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase,aminodeoxychorismate synthase and para-aminobenzoate synthase.; Specificity unclear; putative organic acid synthase 408202..409668 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175569 YP_001221075.1 CDS CMM_0335 NC_009480.1 409681 411495 R conserved membrane protein (NP_531343.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]; NP_384960.1| HYPOTHETICAL TRANSMEMBRANE SIGNAL PEPTIDE PROTEIN [Sinorhizobium meliloti 1021]).; hypothetical protein complement(409681..411495) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175129 YP_001221076.1 CDS CMM_0336 NC_009480.1 411488 411898 R hypothetical protein complement(411488..411898) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175397 YP_001221077.1 CDS CMM_0337 NC_009480.1 411935 413278 R conserved hypothetical protein, putative peptidase (AAP13501.1| Orf12 [Streptomyces clavuligerus]; NP_959400.1| LpqF [Mycobacterium avium subsp. paratuberculosis str. k10]). , weak similarities to: pfam00768, Peptidase_S11, D-alanyl-D-alanine carboxypeptidase.; Function unclear; hypothetical protein complement(411935..413278) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174341 YP_001221078.1 CDS CMM_0338 NC_009480.1 413447 414691 R conserved hypothetical protein (maybe involved in cell wall metabolism; putative N-acetylmuramoyl-l-alanine amidase) (ZP_00235910.1| putative peptidoglycan binding domain protein [Bacillus cereus G9241]; NP_733648.1| hypothetical protein [Streptomyces coelicolor A3(2)]). pfam01471, PG_binding_1, Putative peptidoglycan binding domain.; Function unclear; hypothetical protein complement(413447..414691) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175962 YP_001221079.1 CDS CMM_0339 NC_009480.1 414897 415358 R conserved membrane protein (NP_827521.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]; NP_938697.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam07332,DUF1469, Protein of unknown function (DUF1469). This family consists of several hypothetical bacterial proteins of around 140 residues in length. Members of the family seem to be found exclusively in Actinomycetes. The function of this family is unknown.; Conserved hypothetical protein; hypothetical protein complement(414897..415358) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175786 YP_001221080.1 CDS CMM_0340 NC_009480.1 415448 416053 R Hypothetical protein; hypothetical protein complement(415448..416053) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175902 YP_001221081.1 CDS CMM_0341 NC_009480.1 416050 416628 R Hypothetical protein; hypothetical protein complement(416050..416628) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175911 YP_001221082.1 CDS CMM_0342 NC_009480.1 416625 416999 R hypothetical protein complement(416625..416999) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175797 YP_001221083.1 CDS CMM_0343 NC_009480.1 417181 417618 R conserved hypothetical protein, putative alkaline shock protein (ZP_00189314.2| COG1302: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_827606.1| hypothetical protein SAV6430 [Streptomyces avermitilis MA-4680]). pfam03780, DUF322,Protein of unknown function (DUF322). This is a family of small proteins. It includes a protein identified as an alkaline shock protein, so may be involved in stress response. flhB_rel: FlhB domain protein; putative alkaline shock protein complement(417181..417618) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175374 YP_001221084.1 CDS CMM_0344 NC_009480.1 417819 419000 R putative transcriptional regulator, AraC family (ZP_00024251.1| COG2207: AraC-type DNA-binding domain-containing proteins [Ralstonia metallidurans]; NP_962164.1| hypothetical protein MAP3230c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00165,HTH_AraC, Bacterial regulatory helix-turn-helix proteins,araC family. Members of this family contain two structural repeats of this domain.; High confidence in function and specificity; AraC family transcriptional regulator complement(417819..419000) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175819 YP_001221085.1 CDS CMM_0345 NC_009480.1 419162 420103 R conserved exported protein, putative dessication-related protein (ZP_00227307.1| hypothetical protein Krad06001366 [Kineococcus radiotolerans SRS30216]; ZP_00280800.1| hypothetical protein Bcep02004480 [Burkholderia fungorum LB400]).; Conserved hypothetical protein; hypothetical protein complement(419162..420103) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175732 YP_001221086.1 CDS CMM_0346 NC_009480.1 420329 420871 R conserved membrane protein (ZP_00227499.1| COG1121: ABC-type Mn/Zn transport systems, ATPase component [Kineococcus radiotolerans SRS30216]; NP_821494.1| hypothetical protein SAV320 [Streptomyces avermitilis MA-4680]).; Conserved hypothetical protein; hypothetical protein complement(420329..420871) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175646 YP_001221087.1 CDS manX NC_009480.1 421093 424278 R putative alpha-mannosidase (NP_822929.1| putative alpha-mannosidase [Streptomyces avermitilis MA-4680]; YP_054780.1| glycosyl hydrolase [Propionibacterium acnes KPA171202]). pfam01074, Glyco_hydro_38, Glycosyl hydrolases family 38.; High confidence in function and specificity; putative alpha-mannosidase complement(421093..424278) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173259 YP_001221088.1 CDS bglY NC_009480.1 424342 425685 R putative 6-phospho-beta-glucosidase (NP_822930.1| putative 6-phospho-beta-glucosidase [Streptomyces avermitilis MA-4680]; YP_054779.1| putative glucosidase [Propionibacterium acnes KPA171202]). pfam02056,Glyco_hydro_4, Family 4 glycosyl hydrolase.; High confidence in function and specificity; putative 6-phospho-beta-glucosidase complement(424342..425685) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173178 YP_001221089.1 CDS CMM_0349 NC_009480.1 425682 426407 R putative transcriptional regulator, DeoR family (NP_822931.1| putative DeoR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_624108.1| Transcriptional regulator of sugar metabolism [Thermoanaerobacter tengcongensis]). pfam00455, DeoR,Bacterial regulatory proteins, deoR family. InterPro: Bacterial regulatory protein DeoR family; Specificity unclear; DeoR family transcriptional regulator complement(425682..426407) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173644 YP_001221090.1 CDS CMM_0350 NC_009480.1 426635 427657 D putative carbohydrate kinase (NP_822932.1| putative carbohydrate kinase [Streptomyces avermitilis MA-4680]; ZP_00226288.1| COG0524: Sugar kinases, ribokinase family [Kineococcus radiotolerans SRS30216]). pfam00294, PfkB,pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases.; Specificity unclear; putative carbohydrate kinase 426635..427657 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174916 YP_001221091.1 CDS CMM_0351 NC_009480.1 427733 429019 D putative sugar ABC transporter, substrate binding protein (NP_822933.1| putative sugar binding secreted protein [Streptomyces avermitilis MA-4680]; YP_054776.1| sugar-binding protein [Propionibacterium acnes KPA171202]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter substrate binding protein 427733..429019 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175227 YP_001221092.1 CDS CMM_0352 NC_009480.1 429016 430014 D putative sugar ABC transporter, permease component (NP_822934.1| putative sugar transport system permease [Streptomyces avermitilis MA-4680]; YP_054775.1| transport permease [Propionibacterium acnes KPA171202]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component; Specificity unclear; putative sugar ABC transporter permease 429016..430014 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175079 YP_001221093.1 CDS CMM_0353 NC_009480.1 430011 430934 D putative sugar ABC transporter, permease component (NP_822935.1| putative ABC-type transport system permease protein [Streptomyces avermitilis MA-4680]; YP_054774.1| sugar transport permease BglB [Propionibacterium acnes KPA171202]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component; Specificity unclear; putative sugar ABC transporter permease 430011..430934 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174914 YP_001221094.1 CDS nagB NC_009480.1 430931 431695 D putative glucosamine-6-phosphate deaminase (Glucosamine-6- phosphate isomerase) (Q9K487|NAGB_STRCO Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate isomerase) (GNPDA) (GlcN6P deaminase); ZP_00120662.1| COG0363: 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Bifidobacterium longum DJO10A]). Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity). pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase. nagB: glucosamine-6-phosphate isomerase; High confidence in function and specificity; putative glucosamine-6-phosphate isomerase 430931..431695 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174911 YP_001221095.1 CDS bgaA NC_009480.1 431769 434759 D beta-galactosidase (Lactase) (AAQ19029.1| beta-galactosidase [Arthrobacter sp. SB]; ZP_00226654.1| COG3250: Beta-galactosidase/ beta-glucuronidase [Kineococcus radiotolerans SRS30216]). pfam02837,Glyco_hydro_2_N, Glycosyl hydrolases family 2, sugar binding domain. pfam02836, Glyco_hydro_2_C, Glycosyl hydrolases family 2, TIM barrel domain. pfam02929,Bgal_small_N, Beta galactosidase small chain, N terminal domain. sipfam02930, Bgal_small_C, Beta galactosidase small chain, C terminal domain. This domain is found in the carboxy-terminal portion of the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.; High confidence in function and specificity; beta-galactosidase 431769..434759 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175575 YP_001221096.1 CDS CMM_0356 NC_009480.1 434829 435344 R putative acyl-CoA thioesterase (NP_967633.1| conserved hypothetical protein [Bdellovibrio bacteriovorus HD100]; ZP_00269440.1| hypothetical protein Rrub02001636 [Rhodospirillum rubrum]). pfam03061, 4HBT, Thioesterase superfamily. This family contains a wide variety of enzymes, principally thioesterases. InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site; Specificity unclear; putative acyl-CoA thioesterase complement(434829..435344) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173221 YP_001221097.1 CDS CMM_0357 NC_009480.1 435599 436171 D putative NADPH-dependent FMN reductase (NP_102215.1| hypothetical protein mlr0414 [Mesorhizobium loti MAFF303099]; CAD47912.1| putative NADPH:quinone oxidoreductase [Arthrobacter nicotinovorans]). pfam03358,FMN_red, NADPH-dependent FMN reductase.; Function unclear; hypothetical protein 435599..436171 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174509 YP_001221098.1 CDS CMM_0358 NC_009480.1 436334 437383 D putative transcriptional regulator, LacI family (NP_629820.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00227762.1| COG1609: Transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators.; Specificity unclear; LacI family transcriptional regulator 436334..437383 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174143 YP_001221099.1 CDS CMM_0359 NC_009480.1 437577 438791 D putative sugar ABC transporter, substrate-binding protein (ZP_00192200.3| COG1653: ABC-type sugar transport system, periplasmic component [Kineococcus radiotolerans SRS30216]; NP_625350.1| putative sugar transport sugar binding protein [Streptomyces coelicolor A3(2)]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1; Specificity unclear; putative sugar ABC transporter substrate-binding protein 437577..438791 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174268 YP_001221100.1 CDS CMM_0360 NC_009480.1 438788 439747 D putative sugar ABC trasnporter, permease component (NP_625351.1| putative sugar transport integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00226127.1| COG1175: ABC-type sugar transport systems, permease components [Kineococcus radiotolerans SRS30216]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 438788..439747 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174165 YP_001221101.1 CDS CMM_0361 NC_009480.1 439744 440574 D putative sugar ABC transporter, permease component (NP_625352.1| putative sugar transport integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00226128.1| COG0395: ABC-type sugar transport system, permease component [Kineococcus radiotolerans SRS30216]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 439744..440574 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174362 YP_001221102.1 CDS CMM_0362 NC_009480.1 440654 442702 D putative alpha glucosidase (NP_459046.1| putative glycosyl hydrolase [Salmonella typhimurium LT2]; XP_388973.1| hypothetical protein FG08797.1 [Gibberella zeae PH-1])., pfam01055, Glyco_hydro_31, Glycosyl hydrolases family 31., InterPro: Glycoside hydrolase family 31; Specificity unclear; putative alpha glucosidase 440654..442702 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173839 YP_001221103.1 CDS CMM_0363 NC_009480.1 442816 443871 D putative Fe3+-hydroxamate ABC transporter,substrate binding protein (ZP_00226720.1| COG0614: ABC-type Fe3+-hydroxamate transport system, periplasmic component [Kineococcus radiotolerans SRS30216]; NP_699933.1| iron compound ABC transporter, periplasmic iron compound-binding protein [Brucella suis 1330]). pfam01497, Peripla_BP_2, Periplasmic binding protein. This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport.; Specificity unclear; putative Fe3+-hydroxamate ABC transportersubstrate binding protein 442816..443871 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173720 YP_001221104.1 CDS CMM_0364 NC_009480.1 443868 444944 D putative Fe3+-siderophore ABC transporter, permease component (ZP_00226721.1| COG0609: ABC-type Fe3+-siderophore transport system, permease component [Kineococcus radiotolerans SRS30216]; NP_793040.1| iron ABC transporter, permease protein, putative [Pseudomonas syringae pv. tomato str. DC3000]). pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family.; Specificity unclear; putative Fe3+-siderophore ABC transporterpermease 443868..444944 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175935 YP_001221105.1 CDS CMM_0365 NC_009480.1 444941 445711 D putative Fe3+-siderophore ABC transporter, ATPase component (ZP_00226722.1| COG1120: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Kineococcus radiotolerans SRS30216]; CAB92552.1| FecE protein [Serratia sp. ATCC 39006]). pfam00005, ABC_tran,ABC transporter.; Specificity unclear; putative Fe3+-siderophore ABC transporterATPase 444941..445711 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174524 YP_001221106.1 CDS CMM_0366 NC_009480.1 445786 446586 D putative nucleoside-diphosphate-sugar epimerase (ZP_00291479.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Thermobifida fusca]; AAL17942.1| putative UDP glucose epimerase [Mycobacterium smegmatis]). pfam01370,Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor.; High confidence in function and specificity; putative nucleoside-diphosphate-sugar epimerase 445786..446586 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174286 YP_001221107.1 CDS phnD NC_009480.1 446742 447713 D putative phosphonate ABC transporter, substrate-binding protein (ZP_00110175.1| COG3221: ABC-type phosphate/phosphonate transport system, periplasmic component [Nostoc punctiforme]; NP_946052.1| putative PhnD protein, phosphonate ABC transporter, periplasmic binding protein precursor [Rhodopseudomonas palustris CGA009]). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR ALKYLPHOSPHONATES. InterPro: Bacterial extracellular solute-binding proteins family 3; Specificity unclear; putative phosphonate ABC transporter substrate-binding protein 446742..447713 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174786 YP_001221108.1 CDS phnC NC_009480.1 447735 448634 D putative phosphate/phosphonate ABC transporter,ATPase component (NP_243840.1| alkylphosphonate ABC tranporter (ATP-binding protein) [Bacillus halodurans]; NP_486270.1| ABC tranporter, ATP-binding component [Nostoc sp. PCC 7120]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative phosphate/phosphonate ABC transporterATPase 447735..448634 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174242 YP_001221109.1 CDS phnE NC_009480.1 448631 450379 D putative phosphate/phosphonate ABC transporter,permease component (ZP_00203666.1| COG3639: ABC-type phosphate/phosphonate transport system, permease component [Dechloromonas aromatica RCB]; AAP27494.1| phosphonate ABC transporter, permease protein [Bacillus anthracis str. Ames]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component (twice). InterPro: Binding-protein-dependent transport systems inner membrane component; Specificity unclear; putative phosphate/phosphonate ABC transporterpermease 448631..450379 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174303 YP_001221110.1 CDS panE NC_009480.1 450376 451269 D putative 2-dehydropantoate 2-reductase (NP_337148.1| oxidoreductase, ketopantoate reductase family [Mycobacterium tuberculosis CDC1551]; Q9ABG6|PANE_CAUCR Putative 2-dehydropantoate 2-reductase (Ketopantoate reductase)). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. InterPro: Ketopantoate reductase ApbA/PanE. pfam02558, ApbA,Ketopantoate reductase PanE/ApbA. apbA_panE: 2-dehydropantoate 2-reductas; High confidence in function and specificity; 2-dehydropantoate 2-reductase 450376..451269 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174351 YP_001221111.1 CDS phnX NC_009480.1 451286 451903 R putative acetyltransferase (NP_530883.1| acetyltransferase [Agrobacterium tumefaciens str. C58]; NP_437997.1| putative acetyltransferase protein [Sinorhizobium meliloti 1021]).; Function unclear; putative acetyltransferase complement(451286..451903) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175413 YP_001221112.1 CDS phnN NC_009480.1 451900 452610 R conserved hypothetical protein involved in phosphonate metabolism (NP_085695.1| ATP-binding component of phosphonate transport [Mesorhizobium loti MAFF303099]; AAL52063.1| PHOSPHONATES TRANSPORT ATP-BINDING PROTEIN PHNN [Brucella melitensis 16M]).; Function unclear; hypothetical protein complement(451900..452610) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173795 YP_001221113.1 CDS phnM NC_009480.1 452607 453788 R putative metal-dependent hydrolase involved in phosphonate metabolism (ZP_00195547.1| COG3454: Metal-dependent hydrolase involved in phosphonate metabolism [Mesorhizobium sp. BNC1]; ZP_00124006.1| COG3454: Metal-dependent hydrolase involved in phosphonate metabolism [Pseudomonas syringae pv. syringae B728a]). BELONGS TO AN OPERON INVOLVED IN ALKYLPHOSPHONATE UPTAKE AND C-P LYASE. EXACT FUNCTION NOT KNOWN.; Function unclear; putative metal-dependent hydrolase involved in phosphonate metabolism complement(452607..453788) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173815 YP_001221114.1 CDS phnV NC_009480.1 453785 454531 R Conserved hypothetical protein possibly involved in phosphonate metabolism (ZP_00195546.1| hypothetical protein MBNC02000901 [Mesorhizobium sp. BNC1]; NP_697873.1| conserved hypothetical protein [Brucella suis 1330]). pfam06299, DUF1045, Protein of unknown function (DUF1045). This family consists of several hypothetical proteins from Agrobacterium, Rhizobium and Brucella species. The function of this family is unknown.; Function unclear; hypothetical protein complement(453785..454531) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174030 YP_001221115.1 CDS phnL NC_009480.1 454528 455286 R putative phosphonate ABC transporter, ATPase (NP_104472.1| ATP-binding component of phosphonate transport, HisP-like nucleotide binding protein [Mesorhizobium loti MAFF303099]; NP_767866.1| phosphonate uptake transporter ATP-binding protein [Bradyrhizobium japonicum USDA 110]). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR ALKYLPHOSPHONATES. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative phosphonate ABC transporter ATPase complement(454528..455286) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173843 YP_001221116.1 CDS phnK NC_009480.1 455283 456062 R putative phosphonate ABC transporter, ATPase (NP_530885.1| ABC transporter, nucleotide binding/ATPase protein [phosphonate] [Agrobacterium tumefaciens str. C58]; NP_437995.1| putative phosphonate uptake ABC transporter ATP-binding protein [Sinorhizobium meliloti 1021]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; phosphonate C-P lyase system protein PhnK complement(455283..456062) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173987 YP_001221117.1 CDS phnJ NC_009480.1 456059 456928 R putative C-P (carbon-phosphorus) lyase (NP_418522.1| phosphonate metabolism; conserved protein in phn operon [Escherichia coli K12]; NP_437994.1| putative C-P (carbon-phosphorus) lyase component protein [Sinorhizobium meliloti 1021]). pfam06007, PhnJ,Phosphonate metabolism protein PhnJ.; Specificity unclear; putative C-P (carbon-phosphorus) lyase complement(456059..456928) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173970 YP_001221118.1 CDS phnI NC_009480.1 456925 458040 R conserved hypothetical protein involved in phosphonate metabolism (NP_104468.1| hypothetical protein,; ZP_00205860.1| COG3626: Uncharacterized enzyme of phosphonate metabolism [Pseudomonas syringae pv. syringae B728a]). pfam05861, PhnI, Bacterial phosphonate metabolism protein . Bacteria that use phosphonates as a phosphorus source must be able to break the stable carbon-phosphorus bond. In Escherichia coli phosphonates are broken down by a C-P lyase that has a broad substrate specificity. The genes for phosphonate uptake and degradation in E. coli are organised in an operon of 14 genes, named phnC to phnP. Three gene products (PhnC, PhnD and PhnE) comprise a binding protein-dependent phosphonate transporter, which also transports phosphate, phosphite, and certain phosphate esters such as phosphoserine; two gene products (PhnF and PhnO) may have a role in gene regulation; and nine gene products (PhnG, PhnH, PhnI, PhnJ, PhnK, PhnL,PhnM, PhnN, and PhnP) probably comprise a membrane-associated C-P lyase enzyme complex.; Function unclear; hypothetical protein complement(456925..458040) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174086 YP_001221119.1 CDS phnH NC_009480.1 458040 458687 R putative C-P (carbon-phosphorus) lyase component (NP_104467.1| hypothetical protein, ; NP_946047.1| putative PhnH protein, phosphonate metabolism, function unknown [Rhodopseudomonas palustris CGA009]). pfam05845,PhnH, Bacterial phosphonate metabolism protein .; Function unclear; putative C-P (carbon-phosphorus) lyase component complement(458040..458687) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174151 YP_001221120.1 CDS phnG NC_009480.1 458684 459175 R putative C-P (carbon-phosphorus lyase component (NP_530889.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]; NP_437991.1| putative C-P (carbon-phosphorus lyase component protein [Sinorhizobium meliloti 1021]). pfam06754, PhnG,Phosphonate metabolism protein PhnG. The exact function of PhnG is unknown, however it is thought likely that along with six other proteins PhnG makes up the the C-P (carbon-phosphorus) lyase.; Function unclear; putative C-P (carbon-phosphorus lyase component complement(458684..459175) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174108 YP_001221121.1 CDS phnF NC_009480.1 459383 460120 D putative transcriptional regulator, GntR family (NP_530890.1| transcriptional regulator, GntR family [Agrobacterium tumefaciens str. C58 (U. Washington)]; NP_698105.1| transcriptional regulator, GntR family [Brucella suis 1330]). putative regulator of the phn operon. pfam00392, GntR, Bacterial regulatory proteins,gntR family. This domain comprises the N-terminal HTH-containing region of GntR-like bacterial transcription factors. At the C terminus there is usually an effector-binding/oligomerisation domain. InterPro: Bacterial regulatory proteins GntR family.; Specificity unclear; GntR family transcriptional regulator 459383..460120 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174194 YP_001221122.1 CDS CMM_0382 NC_009480.1 460220 461437 D putative multidrug efflux MFS permease (NP_737817.1| putative multidrug resistance protein [Corynebacterium efficiens YS-314]; NP_962079.1| hypothetical protein MAP3145c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative multidrug efflux MFS permease 460220..461437 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174320 YP_001221123.1 CDS ppcA NC_009480.1 461542 464274 D phosphoenolpyruvate carboxylase (ZP_00293827.1| COG2352: Phosphoenolpyruvate carboxylase [Thermobifida fusca]; NP_695792.1| phosphoenolpyruvate carboxylase [Bifidobacterium longum NCC2705]). pfam00311, PEPcase,Phosphoenolpyruvate carboxylase.; High confidence in function and specificity; hypothetical protein 461542..464274 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173232 YP_001221124.1 CDS CMM_0384 NC_009480.1 464495 464998 R putative transcriptional regulator, Cro/CI family (NP_863201.1| hypothetical protein [Staphylococcus epidermidis ATCC 12228]; NP_900580.1| hypothetical protein CV0910 [Chromobacterium violaceum ATCC 12472]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator complement(464495..464998) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173911 YP_001221125.1 CDS ltaE NC_009480.1 465146 466255 R putative L-threonine aldolase (NP_822663.1| putative L-threonine aldolase [Streptomyces avermitilis MA-4680]; YP_011095.1| threonine aldolase, low-specificity [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough]). Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine L-threo-phenylserine L-beta-34- methylenedioxyphenylserine and L-beta-34-dihydroxyphenylserine.; High confidence in function and specificity; putative L-threonine aldolase complement(465146..466255) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174963 YP_001221126.1 CDS CMM_0386 NC_009480.1 466292 466948 R putative NTP pyrophosphohydrolase (NP_624609.1| conserved hypothetical protein SCF85.08c [Streptomyces coelicolor A3(2)]; ZP_00229098.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Kineococcus radiotolerans SRS30216]). pfam00293,NUDIX, NUDIX domain.; Function unclear; putative NTP pyrophosphohydrolase complement(466292..466948) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174566 YP_001221127.1 CDS CMM_0387 NC_009480.1 467019 468287 R putative sulfide:quinone oxidoreductase (NP_440916.1| hypothetical protein [Synechocystis sp. PCC 6803]; ZP_00084090.1| COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases [Pseudomonas fluorescens PfO-1]). , pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases.; Function unclear; putative NAD(FAD)-dependent dehydrogenase complement(467019..468287) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175772 YP_001221128.1 CDS CMM_0388 NC_009480.1 468608 469054 D putative stress-like protein (; NP_626104.1| putative stress-like protein [Streptomyces coelicolor A3(2)]). pfam03780, DUF322, Protein of unknown function (DUF322). This is a family of small proteins. It includes a protein identified as an alkaline shock protein, so may be involved in stress response.; Function unclear; putative alkaline shock protein 468608..469054 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175098 YP_001221129.1 CDS aqpZ NC_009480.1 469277 470095 D putative Aquaporin (ZP_00032143.1| COG0580: Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Burkholderia fungorum]; NP_884218.1| aquaporin Z [Bordetella parapertussis 12822]). Transport of water across the membrane. Possibly involved in the adaptation to variation in intravacuolar pH or osmolarity. MIP: MIP family channel proteins pfam00230, MIP, Major intrinsic protein. MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.; High confidence in function and specificity; hypothetical protein 469277..470095 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175087 YP_001221130.1 CDS CMM_0390 NC_009480.1 470190 471176 D hypothetical protein (similarities of the N-terminal part to: ZP_00189314.2| COG1302: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_626104.1| putative stress-like protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 470190..471176 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175858 YP_001221131.1 CDS CMM_0391 NC_009480.1 471212 471784 R hypothetical protein (ZP_00057389.1| hypothetical protein [Thermobifida fusca]; CAF19543.1| secreted protein [Corynebacterium glutamicum ATCC 13032]).; hypothetical protein complement(471212..471784) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175051 YP_001221132.1 CDS CMM_0392 NC_009480.1 471875 472327 R conserved hypothetical protein (ZP_00223109.1| COG3152: Predicted membrane protein [Burkholderia cepacia R1808]; NP_708910.1| putative cytochrome [Shigella flexneri 2a str. 301]). pfam05656, DUF805, Protein of unknown function (DUF805).; Function unclear; hypothetical protein complement(471875..472327) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175034 YP_001221133.1 CDS CMM_0393 NC_009480.1 472374 473138 R conserved hypothetical protein (NP_854517.1| HYPOTHETICAL PROTEIN [Mycobacterium bovis subsp. bovis AF2122/97]; BAC00185.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032]).; Function unclear; hypothetical protein complement(472374..473138) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174906 YP_001221134.1 CDS CMM_0394 NC_009480.1 473188 474225 R conserved hypothetical protein (NP_215352.1| hypothetical protein Rv0837c [Mycobacterium tuberculosis H37Rv]; NP_601982.1| hypothetical protein NCgl2692 [Corynebacterium glutamicum ATCC 13032])).; Function unclear; hypothetical protein complement(473188..474225) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173079 YP_001221135.1 CDS CMM_0395 NC_009480.1 474322 474789 R putative membrane protein (H83813 hypothetical protein BH1312 [imported] - Bacillus halodurans (strain C-125)).; Function unclear; hypothetical protein complement(474322..474789) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173943 YP_001221136.1 CDS CMM_0396 NC_009480.1 474786 475919 R putative Na+ efflux ABC transporter, permease component (ZP_00227879.1| COG1668: ABC-type Na+ efflux pump, permease component [Kineococcus radiotolerans SRS30216]; AAF04136.1| hypothetical ABC transporter [Mycobacterium smegmatis]).; Function unclear; putative Na+ efflux ABC transporter permease complement(474786..475919) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175215 YP_001221137.1 CDS CMM_0397 NC_009480.1 475916 476797 R putative ABC-Transporter, ATP binding protein (ZP_00227878.1| COG4152: ABC-type uncharacterized transport system, ATPase component [Kineococcus radiotolerans SRS30216]; AAF04137.1| hypothetical ABC transporter [Mycobacterium smegmatis]). InterPro: AAA ATPase superfamily pfam00005, ABC_tran, ABC transporter.; Function unclear; putative ABC transporter ATP-binding protein complement(475916..476797) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174119 YP_001221138.1 CDS CMM_0398 NC_009480.1 476999 477448 D Hypothetical protein; hypothetical protein 476999..477448 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175516 YP_001221139.1 CDS CMM_0399 NC_009480.1 477439 478344 R conserved hypothetical protein, eventually Ca2+-binding (NP_978918.1| regucalcin family protein [Bacillus cereus ATCC 10987]; NP_626682.1| putative calcium-binding protein [Streptomyces coelicolor A3(2)]).; Family membership; hypothetical protein complement(477439..478344) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174223 YP_001221140.1 CDS CMM_0400 NC_009480.1 478341 479135 R putative short chain dehydrogenase (ZP_00226079.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; CAF21988.1| Subunit of 2-[hydroxy(phenyl)methyl]-succinyl-CoA DH; bbsD [Azoarcus sp. EbN1]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short chain dehydrogenase complement(478341..479135) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174273 YP_001221141.1 CDS CMM_0401 NC_009480.1 479188 479970 D putative short-chain alcohol dehydrogenase (ZP_00226078.1| COG1028: dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; NP_767148.1| hypothetical oxidoreductase [Bradyrhizobium japonicum]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short-chain alcohol dehydrogenase 479188..479970 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174847 YP_001221142.1 CDS CMM_0402 NC_009480.1 479989 480438 R hypothetical protein complement(479989..480438) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175879 YP_001221143.1 CDS glpT NC_009480.1 480919 482340 D putative glycerol-3-phosphate MFS permease (NP_938673.1| Putative glycerol-3-phosphate transporter [Corynebacterium diphtheriae]; AAL21184.1| MFS family, sn-glycerol-3-phosphate transport protein [Salmonella typhimurium LT2]). Responsible for glycerol-3-phosphate uptake. pfam00083, Sugar_tr, Sugar (and other) transporter. 2A0104: phosphoglycerate transporter pr; High confidence in function and specificity; putative glycerol-3-phosphate MFS permease 480919..482340 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174228 YP_001221144.1 CDS CMM_0404 NC_009480.1 482363 483100 R putative two-component system response regulator (NP_625929.1| putative two-component response regulator [Streptomyces coelicolor A3(2)]; ZP_00227053.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]). InterPro: Response regulator receiver domain pfam00072, Response_reg, Response regulator receiver domain. pfam00196, GerE, Bacterial regulatory proteins,luxR family.; Specificity unclear; putative two-component system response regulator complement(482363..483100) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174121 YP_001221145.1 CDS CMM_0405 NC_009480.1 483097 484506 R putative two-component system, sensor kinase (NP_825857.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; NP_627597.1| putative two component sensor kinase [Streptomyces coelicolor A3(2)]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.; Specificity unclear; putative two-component system, sensor kinase complement(483097..484506) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174271 YP_001221146.1 CDS CMM_0406 NC_009480.1 484813 486405 D putative drug efflux MFS permease (NP_472303.1| ; NP_627413.1| putative transmembrane efflux protein [Streptomyces coelicolor A3(2)]). pfam00083, Sugar_tr,Sugar (and other) transporter. InterPro: General substrate transporters 2_A_01_02: Multidrug resistance protein; Specificity unclear; putative drug efflux MFS permease 484813..486405 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174440 YP_001221147.1 CDS CMM_0407 NC_009480.1 486491 487339 R putative hydrolase (ZP_00226479.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Kineococcus radiotolerans SRS30216]; NP_826888.1| putative alpha/beta hydrolase fold family protein [Streptomyces avermitilis MA-4680]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; alpha/beta fold family hydrolase complement(486491..487339) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174950 YP_001221148.1 CDS CMM_0408 NC_009480.1 487427 488134 D hypothetical protein 487427..488134 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174693 YP_001221149.1 CDS CMM_0409 NC_009480.1 488148 488861 R oxidoreductase (ZP_00227286.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; AAD46515.1| oxidoreductase homolog [Streptomyces albus]). InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily pfam00106,adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative oxidoreductase complement(488148..488861) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175324 YP_001221150.1 CDS CMM_0410 NC_009480.1 488994 489413 D putative transcriptional regulator, MerR-family (ZP_00191407.2| COG0789: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]; CAE53385.1| putative transcriptional regulator, MerR family [Actinoplanes teichomyceticus]). pfam00376, MerR,MerR family regulatory protein.; Specificity unclear; MerR family transcriptional regulator 488994..489413 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174708 YP_001221151.1 CDS CMM_0411 NC_009480.1 489604 490074 D hypothetical protein 489604..490074 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174605 YP_001221152.1 CDS CMM_0412 NC_009480.1 490088 490267 D hypothetical protein 490088..490267 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174616 YP_001221153.1 CDS CMM_0413 NC_009480.1 490374 490736 R hypothetical protein complement(490374..490736) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173874 YP_001221154.1 CDS CMM_0414 NC_009480.1 490826 491362 D putative transcriptional regulator, MarR family (NP_899880.1| probable transcriptional regulator, MarR family [Chromobacterium violaceum ATCC 12472]; NP_348196.1| Transcriptional regulators, MarR/EmrR family [Clostridium acetobutylicum]). InterPro: Bacterial regulatory protein MarR family. pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 490826..491362 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174385 YP_001221155.1 CDS osmC NC_009480.1 491439 491861 D putative organic hydroperoxide resistance protein (NP_599276.2| stress-induced protein [Corynebacterium glutamicum ATCC 13032]; NP_834187.1| Osmotically inducible protein C [Bacillus cereus ATCC 14579]). pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.; High confidence in function and specificity; organic hydroperoxide resistance protein 491439..491861 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174096 YP_001221156.1 CDS CMM_0416 NC_009480.1 491861 492268 D putative membrane protein (NP_295648.1| hypothetical protein [Deinococcus radiodurans R1]; ZP_00209412.1| hypothetical protein Magn023696 [Magnetospirillum magnetotacticum]).; Function unclear; hypothetical protein 491861..492268 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175279 YP_001221157.1 CDS CMM_0417 NC_009480.1 492406 492837 D conserved hypothetical protein (NP_883401.1| conserved hypothetical protein [Bordetella parapertussis 12822]; ZP_00032237.1| COG3607: Predicted lactoylglutathione lyase [Burkholderia fungorum]). InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 492406..492837 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174573 YP_001221158.1 CDS CMM_0418 NC_009480.1 492847 493980 R putative epoxide hydrolase (ZP_00229095.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Kineococcus radiotolerans SRS30216]; NP_347356.1| Epoxide hydrolase,; Function unclear; putative epoxide hydrolase complement(492847..493980) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175963 YP_001221159.1 CDS CMM_0419 NC_009480.1 493997 495226 R conserved hypothetical protein, putative HTH-type transcriptional regulator (NP_737943.1| hypothetical protein [Corynebacterium efficiens YS-314]; NP_695848.1| hypothetical protein BL0662 [Bifidobacterium longum NCC2705]).; Function unclear; hypothetical protein complement(493997..495226) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175979 YP_001221160.1 CDS CMM_0420 NC_009480.1 495310 496368 R putative sugar ABC transporter, permease component (NP_695267.1| probable ABC transporter permease protein for sugars [Bifidobacterium longum NCC2705]; ZP_00182437.2| COG1172:ribose/xylose/arabinose/ galactoside ABC-type transport systems, permease components Exiguobacterium sp. 255-15]). pfam02653,BPD_transp_2, Branched-chain amino acid transport system / permease component.Also found with in this family are proteins from the galactose transport system permease, and a ribose transport system.; Specificity unclear; putative sugar ABC transporter membrane spanning protein complement(495310..496368) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175945 YP_001221161.1 CDS CMM_0421 NC_009480.1 496365 497447 R putative sugar ABC transporter, permease component (NP_695266.1| probable ABC transport system permease protein for sugars [Bifidobacterium longum NCC2705]; ZP_00066972.1| COG1172: Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Microbulbifer degradans 2-40]). InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) pfam02653,BPD_transp_2, Branched-chain amino acid transport system / permease component.; Specificity unclear; putative sugar ABC transporter permease complement(496365..497447) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174592 YP_001221162.1 CDS CMM_0422 NC_009480.1 497444 499018 R putative sugar ABC transporter, ATPase component (NP_695265.1| ATP binding protein of ABC transporter [Bifidobacterium longum NCC2705]; NP_437568.1| putative sugar uptake ABC transporter ATP-binding protein [Sinorhizobium meliloti 1021]). pfam00005, ABC_tran, ABC transporter (2 times).; Specificity unclear; putative sugar ABC transporter ATPase complement(497444..499018) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175540 YP_001221163.1 CDS CMM_0423 NC_009480.1 499112 500116 R putative sugar ABC transporter, binding protein (ZP_00121662.1| COG1879: ABC-type sugar transport system,periplasmic component [Bifidobacterium longum DJO10A]; ZP_00223066.1| COG1879: ABC-type sugar transport system,periplasmic component [Burkholderia cepacia R1808]).; Specificity unclear; putative sugar ABC transporter binding protein complement(499112..500116) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175151 YP_001221164.1 CDS CMM_0424 NC_009480.1 500283 501956 R putative sugar uptake ABC transporter, ATPase component (NP_695265.1| ATP binding protein of ABC transporter [Bifidobacterium longum NCC2705]; ZP_00223067.1| COG1129: ABC-type sugar transport system,ATPase component [Burkholderia cepacia R1808]). pfam00005,ABC_tran, ABC transporter (duplicated domain).; Specificity unclear; putative sugar uptake ABC transporter ATPase complement(500283..501956) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174638 YP_001221165.1 CDS CMM_0425 NC_009480.1 502082 503104 R putative transcriptional regulator, LacI family (NP_630441.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_822206.1| putative LacI-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain (pfam00356).; Specificity unclear; LacI family transcriptional regulator complement(502082..503104) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173769 YP_001221166.1 CDS CMM_0426 NC_009480.1 503366 504322 D putative manganese-containing catalase (ZP_00235296.1| manganese catalase [Bacillus cereus G9241]; CAE09059.1| mn catalase [Thermus thermophilus]). pfam05067, Mn_catalase, Manganese containing catalase. Catalases are important antioxidant metalloenzymes that catalyse disproportionation of hydrogen peroxide, forming dioxygen and water. Two families of catalases are known,one having a heme cofactor, and this family that is a structurally distinct family containing non-heme manganese.; High confidence in function and specificity; manganese-containing catalase 503366..504322 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175661 YP_001221167.1 CDS CMM_0427 NC_009480.1 506213 506389 D hypothetical protein , weak similarity to: pfam01476, LysM, LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function.; hypothetical protein 506213..506389 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175210 YP_001221168.1 CDS CMM_0428 NC_009480.1 506602 509040 D putative phosphoketolase (Q8YTZ6|PHK2_ANASP Probable phosphoketolase 2; NP_960507.1| hypothetical protein MAP1573c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam03894, XFP, D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase. Bacterial enzyme splits fructose-6-P and/or xylulose-5-P with the aid of inorganic phosphate into either acetyl-P and erythrose-4-P and/or acetyl-P and glyeraldehyde-3-P EC:4.1.2.9, EC:4.1.2.22.; Specificity unclear; putative phosphoketolase 506602..509040 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175776 YP_001221169.1 CDS CMM_0429 NC_009480.1 509091 509840 R putative secreted protein (ZP_00413710.1| S-layer homology region [Arthrobacter sp. FB24]).; Hypothetical protein; hypothetical protein complement(509091..509840) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175259 YP_001221170.1 CDS CMM_0430 NC_009480.1 509932 511758 R hypothetical secreted protein, putative cell-surface protein (only weak similarities, putative N-terminal RTX toxin and C-terminal fibrinogen-binding domain; ZP_00413710.1| S-layer homology region [Arthrobacter sp. FB24]).; Hypothetical protein; hypothetical protein complement(509932..511758) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175959 YP_001221171.1 CDS CMM_0431 NC_009480.1 511928 514192 R putative secreted hemagglutinin/hemolysin-related protein (NP_868824.1| probable fibrinogen-binding protein homolog-putative involved in cell-cell interaction [Pirellula sp. 1]; also similarities to membrane proteins of unknown function: NP_628213.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]).; Function unclear; putative hemagglutinin/hemolysin-like protein complement(511928..514192) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175970 YP_001221172.1 CDS CMM_0432 NC_009480.1 514407 515069 D conserved hypothetical protein (NP_600647.1| uncharacterized low-complexity protein [Corynebacterium glutamicum ATCC 13032]; NP_628440.1| hypothetical protein [Streptomyces coelicolor A3(2)])., , pfam00805,Pentapeptide, Pentapeptide repeats (8 copies).; hypothetical protein 514407..515069 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175334 YP_001221173.1 CDS fepG NC_009480.1 515083 516114 R putative iron-siderophore ABC transporter, permease component (BAB97894.1| ABC-type transporter, permease components [Corynebacterium glutamicum ATCC 13032]; AAD29086.1| FepG [Yersinia enterocolitica]; NP_626057.1| putative iron-siderophore uptake system transmembrane component [Streptomyces coelicolor A3(2)]). pfam01032,FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.; Specificity unclear; putative iron-siderophore ABC transporterpermease complement(515083..516114) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175306 YP_001221174.1 CDS fepD NC_009480.1 516111 517118 R putative iron-siderophore ABC transporter, permease component (BAB97895.1| ABC-type transporter, permease components [Corynebacterium glutamicum ATCC 13032]; NP_626058.1| putative iron-siderophore uptake system transmembrane component [Streptomyces coelicolor A3(2)]; AAD29085.1| FepD [Yersinia enterocolitica]). InterPro: FecCD transport family pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.; Specificity unclear; putative iron-siderophore ABC transporterpermease complement(516111..517118) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173350 YP_001221175.1 CDS fepB NC_009480.1 517149 518225 D putative iron-siderophore ABC transporter, binding protein (BAC00469.1| ABC-type Fe3+-siderophores transport systems, periplasmic components [Corynebacterium glutamicum ATCC 13032]; pfam01497, Peripla_BP_2,Periplasmic binding protein. This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport.; Specificity unclear; putative iron-siderophore ABC transporterbinding protein 517149..518225 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173397 YP_001221176.1 CDS CMM_0436 NC_009480.1 518235 518756 R putative acetyltransferase (NP_103315.1| probable transcriptional regulator [Mesorhizobium loti MAFF303099]; BAA06228.1| regulatory protein for C-P lyase [Streptomyces griseus]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(518235..518756) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173277 YP_001221177.1 CDS CMM_0437 NC_009480.1 518809 519558 D putative SAM-dependant methyltransferase (NP_631493.1| hypothetical protein SC5C11.02. [Streptomyces coelicolor A3(2)]; NP_418726.1| putative methyltransferase [Escherichia coli K12]). pfam02390,Methyltransf_4, Putative methyltransferase.; Conserved hypothetical protein; putative SAM-dependent methyltransferase 518809..519558 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175333 YP_001221178.1 CDS CMM_0438 NC_009480.1 519626 520414 R putative hydrolase (NP_350247.1| Alpha/beta superfamily hydrolase [Clostridium acetobutylicum]; NP_623397.1| Hydrolases of the alpha/beta superfamily [Thermoanaerobacter tengcongensis]). pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase complement(519626..520414) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175854 YP_001221179.1 CDS padA NC_009480.1 520414 520944 R putative phenolic acid decarboxylase (NP_959619.1| hypothetical protein MAP0685 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_391320.1| ferulate decarboxylase [Bacillus subtilis]). pfam05870,PA_decarbox, Phenolic acid decarboxylase (PAD). This family consists of several bacterial phenolic acid decarboxylase proteins. Phenolic acids, also called substituted cinnamic acids, are important lignin-related aromatic acids and natural constituents of plant cell walls. These acids (particularly ferulic, p-coumaric, and caffeic acids) bind the complex lignin polymer to the hemicellulose and cellulose in plants. The Phenolic acid decarboxylase (PAD) gene (pad) is transcriptionally regulated by p-coumaric, ferulic, or caffeic acid; these three acids are the three substrates of PAD.; Specificity unclear; putative phenolic acid decarboxylase complement(520414..520944) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174728 YP_001221180.1 CDS CMM_0440 NC_009480.1 521008 521508 D putative transcriptional regulator, MarR family (NP_824165.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; ZP_00081183.1| COG1846: Transcriptional regulators [Geobacter metallireducens]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; hypothetical protein 521008..521508 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175359 YP_001221181.1 CDS CMM_0441 NC_009480.1 521634 522209 D hypothetical protein 521634..522209 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175141 YP_001221182.1 CDS CMM_0442 NC_009480.1 522274 522888 D hypothetical protein 522274..522888 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173917 YP_001221183.1 CDS CMM_0443 NC_009480.1 522987 523577 R putative MarR-family transcriptional regulator (NP_824140.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_629432.1| putative MarR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam01047,MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR.; Specificity unclear; MarR family transcriptional regulator complement(522987..523577) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175363 YP_001221184.1 CDS CMM_0444 NC_009480.1 523574 525331 R putative MFS permease (NP_628213.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]; ZP_00226711.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). TIGRFAM (TIGR00711): drug resistance transporter, EmrB/QacA subfamily.; Specificity unclear; MFS family transporter complement(523574..525331) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174343 YP_001221185.1 CDS CMM_0445 NC_009480.1 525500 525856 D conserved hypothetical protein (ZP_00071215.1| hypothetical protein [Trichodesmium erythraeum IMS101]; NP_968301.1| putative glyoxalase [Bdellovibrio bacteriovorus HD100]). InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily pfam00903,Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; hypothetical protein 525500..525856 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173778 YP_001221186.1 CDS CMM_0446 NC_009480.1 525870 527021 R putative Xaa-Pro dipeptidase (NP_343867.1| Prolidase (Xaa-Pro dipeptidase) (pepQ-like3) [Sulfolobus solfataricus P2]; NP_635937.1| Xaa-Pro dipeptidase [Xanthomonas campestris pv. campestris str. ATCC 33913]).; Function unclear; putative peptidase complement(525870..527021) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175906 YP_001221187.1 CDS CMM_0447 NC_009480.1 527021 527329 R conserved hypothetical protein (NP_821812.1| hypothetical protein SAV637 [Streptomyces avermitilis MA-4680]; NP_714492.1| conserved hypothetical protein [Leptospira interrogans serovar lai str. 56601]).; hypothetical protein complement(527021..527329) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174487 YP_001221188.1 CDS CMM_0448 NC_009480.1 527347 527865 R hypothetical protein complement(527347..527865) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174624 YP_001221189.1 CDS CMM_0449 NC_009480.1 527872 528774 R hypothetical protein complement(527872..528774) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174813 YP_001221190.1 CDS CMM_0450 NC_009480.1 528865 529494 R putative oxidoreductase (NP_822664.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]; NP_902034.1| acetoacetyl-CoA reductase [Chromobacterium violaceum ATCC 12472]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Hypothetical protein; hypothetical protein complement(528865..529494) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175355 YP_001221191.1 CDS CMM_0451 NC_009480.1 529491 530912 R hypothetical protein (NP_625383.1| hypothetical protein 2SCG4.05c [Streptomyces coelicolor A3(2)]; NP_625383.1| hypothetical protein 2SCG4.05c [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(529491..530912) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175143 YP_001221192.1 CDS CMM_0452 NC_009480.1 531050 531616 R putative acetyltransferase (NP_253367.1| peptide n-acetyltransferase RimI [Pseudomonas aeruginosa PA01]; ZP_00088630.1| COG0456: Acetyltransferases [Azotobacter vinelandii]). , pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(531050..531616) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175222 YP_001221193.1 CDS pitA NC_009480.1 531745 532962 D puative low-affinity inorganic phosphate permease (ZP_00227554.1| COG0306: Phosphate/sulphate permeases [Kineococcus radiotolerans SRS30216]; NP_737084.1| putative phosphate transport protein PitA [Corynebacterium efficiens YS-314]). pfam01384, PHO4, Phosphate transporter family.; High confidence in function and specificity; low affinity phosphate permease 531745..532962 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175174 YP_001221194.1 CDS CMM_0454 NC_009480.1 532974 533285 D putative membrane protein (NP_737083.1| hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00227553.1| hypothetical protein Krad06004394 [Kineococcus radiotolerans SRS30216]).; Conserved hypothetical protein; hypothetical protein 532974..533285 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173624 YP_001221195.1 CDS CMM_0455 NC_009480.1 533288 533998 D conserved hypothetical protein, putative fusion protein containing duplicated domain (NP_962973.1| hypothetical protein MAP4039c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00198152.1| hypothetical protein Krad06004393 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 533288..533998 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175145 YP_001221196.1 CDS CMM_0456 NC_009480.1 534030 534233 R hypothetical protein complement(534030..534233) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175785 YP_001221197.1 CDS CMM_0457 NC_009480.1 534450 535112 D putative transcriptional regulator, TetR family (NP_599627.1| transcriptional regulator [Corynebacterium glutamicum ATCC 13032]; AAM94766.1| CalR1 [Micromonospora echinospora]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 534450..535112 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174789 YP_001221198.1 CDS CMM_0458 NC_009480.1 535109 536812 D putative MFS permease (ZP_00229023.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_599629.1| permease of the major facilitator superfamily [Corynebacterium glutamicum ATCC 13032]). InterPro: Drug resistance transporter EmrB/QacA subfamily pfam00083,Sugar_tr, Sugar (and other) transporter. TIGRFAM (TIGR00711): drug resistance transport protein; Function unclear; MFS-type efflux permease 535109..536812 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175954 YP_001221199.1 CDS CMM_0459 NC_009480.1 536932 537375 D conserved hypothetical protein (NP_627085.1| hypothetical protein SCE20.30. [Streptomyces coelicolor A3(2)]; NP_438059.1| CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti 1021]). pfam05146, DUF704, Aha1 domain. The function of this presumed domain is unknown.; Function unclear; hypothetical protein 536932..537375 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174436 YP_001221200.1 CDS CMM_0460 NC_009480.1 537372 539066 R conserved hypothetical protein (ZP_00120870.2| hypothetical protein Blon020749 [Bifidobacterium longum DJO10A]; ZP_00218065.1| hypothetical protein Bcepa02000673 [Burkholderia cepacia R18194]).; hypothetical protein complement(537372..539066) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175769 YP_001221201.1 CDS CMM_0461 NC_009480.1 539259 540188 D putative permease, AEC family (NP_696444.1| hypothetical protein with unknown or transport function [Bifidobacterium longum NCC2705]; ZP_00189944.2| COG0679: Predicted permeases [Kineococcus radiotolerans SRS30216] 2a69: Auxin Efflux Carrier pfam03547, Auxin_eff, Auxin Efflux Carrier. This family of transporters are found in all domains of life.; Specificity unclear; permease AEC family 539259..540188 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173895 YP_001221202.1 CDS CMM_0462 NC_009480.1 540201 540359 R hypothetical protein complement(540201..540359) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174254 YP_001221203.1 CDS CMM_0463 NC_009480.1 540498 540974 R putative acetyltransferase (ZP_00184384.1| hypothetical protein Exigu007901 [Exiguobacterium sp. 255-15]; ZP_00062966.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293] pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Family membership; putative acetyltransferase complement(540498..540974) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174324 YP_001221204.1 CDS CMM_0464 NC_009480.1 541062 542021 R putative sugar reductase (NP_625517.1| putative reductase [Streptomyces coelicolor A3(2)]; CAF21980.1| Sugar dehydratase [Azoarcus sp. EbN1]).; Family membership; hypothetical protein complement(541062..542021) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175808 YP_001221205.1 CDS CMM_0465 NC_009480.1 542537 543241 R hypothetical protein complement(542537..543241) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175922 YP_001221206.1 CDS CMM_0466 NC_009480.1 543275 544162 R conserved hypothetical protein (NP_828650.1| hypothetical protein SAV7474 [Streptomyces avermitilis MA-4680]; NP_293888.1| endo alpha-1,4 polygalactosaminidase,putative [Deinococcus radiodurans R1]).; Function unclear; hypothetical protein complement(543275..544162) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175896 YP_001221207.1 CDS CMM_0467 NC_009480.1 544172 544609 R conserved hypothetical protein (NP_695944.1| narrowly conserved hypothetical protein [Bifidobacterium longum NCC2705]; NP_358299.1| Conserved hypothetical protein [Streptococcus pneumoniae R6]). pfam06171, DUF984,Protein of unknown function (DUF984).; Function unclear; hypothetical protein complement(544172..544609) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175743 YP_001221208.1 CDS CMM_0468 NC_009480.1 544648 544995 R Hypothetical protein; hypothetical protein complement(544648..544995) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174395 YP_001221209.1 CDS CMM_0469 NC_009480.1 545154 546062 D putative oxidoreductase (NP_636454.1| oxidoreductase [Xanthomonas campestris pv. campestris str. ATCC 33913]; NP_535107.1| oxidoreductase [Agrobacterium tumefaciens str. C58]). pfam00106, adh_short, short chain dehydrogenase; Function unclear; putative oxidoreductase 545154..546062 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175827 YP_001221210.1 CDS CMM_0470 NC_009480.1 546093 546659 R conserved hypothetical protein (NP_862390.1| MC12 [Micrococcus sp. 28]; ZP_00225867.1| hypothetical protein Krad06004329 [Kineococcus radiotolerans SRS30216]). pfam03473, MOSC, MOSC domain. The MOSC (MOCO sulfurase C-terminal) domain is a superfamily of beta-strand-rich domains identified in the molybdenum cofactor sulfurase and several other proteins from both prokaryotes and eukaryotes.; Function unclear; hypothetical protein complement(546093..546659) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174803 YP_001221211.1 CDS CMM_0471 NC_009480.1 546768 548468 D putative two-component sensor histidine kinase (NP_834294.1| Phosphate regulon sensor protein phoR [Bacillus cereus ATCC 14579]; ZP_00061962.1| COG5002: Signal transduction histidine kinase [Clostridium thermocellum ATCC 27405]). pfam00512, HisKA, His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component sensor histidine kinase 546768..548468 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175918 YP_001221212.1 CDS CMM_0472 NC_009480.1 548510 549385 D hypothetical protein 548510..549385 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175844 YP_001221213.1 CDS CMM_0473 NC_009480.1 549618 550475 R putative two-component system response regulator (ZP_00019357.1| hypothetical protein [Chloroflexus aurantiacus]; NP_602156.1| two-component system, response regulator [Corynebacterium glutamicum ATCC 13032]). InterPro: Response regulator receiver domain pfam00072,Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. pfam00486,Trans_reg_C, Transcriptional regulatory protein, C terminal.; Specificity unclear; putative two-component system response regulator complement(549618..550475) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174472 YP_001221214.1 CDS CMM_0474 NC_009480.1 550605 551192 R putative membrane protein (only very weak similarities to histidine kinases, two-component regulators); Hypothetical protein; hypothetical protein complement(550605..551192) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173856 YP_001221215.1 CDS xthB NC_009480.1 551281 552117 R Exodeoxyribonuclease III (ZP_00227856.1| COG0708: Exonuclease III [Kineococcus radiotolerans SRS30216]; CAB06567.1| PROBABLE EXODEOXYRIBONUCLEASE III PROTEIN XTHA (EXONUCLEASE III) (EXO III) (AP ENDONUCLEASE VI) [Mycobacterium tuberculosis H37Rv]). , pfam03372,Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family.; High confidence in function and specificity; putative exonuclease III complement(551281..552117) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175904 YP_001221216.1 CDS CMM_0476 NC_009480.1 556093 556488 R hypothetical protein complement(556093..556488) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174193 YP_001221217.1 CDS CMM_0477 NC_009480.1 556485 557234 R hypothetical protein , , pfam03780, DUF322, Protein of unknown function (DUF322). This is a family of small proteins. It includes a protein identified as an alkaline shock protein, so may be involved in stress response.; hypothetical protein complement(556485..557234) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174230 YP_001221218.1 CDS sigZ NC_009480.1 557231 557785 R ECF sigma factor (ZP_00198063.1| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Kineococcus radiotolerans SRS30216]; ZP_00179997.2| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Moorella thermoacetica ATCC 39073]). pfam04542, Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. pfam04545, Sigma70_r4, Sigma-70,region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.; Specificity unclear; putative ECF sigma factor complement(557231..557785) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175278 YP_001221219.1 CDS CMM_0479 NC_009480.1 557918 558391 D conserved hypothetical protein (ZP_00189314.2| COG1302: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_626104.1| putative stress-like protein [Streptomyces coelicolor A3(2)]). pfam03780, DUF322, Protein of unknown function (DUF322). This is a family of small proteins. It includes a protein identified as an alkaline shock protein, so may be involved in stress response.; hypothetical protein 557918..558391 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175095 YP_001221220.1 CDS CMM_0480 NC_009480.1 558564 559439 D putative beta-hydroxyacid dehydrogenase (NP_822718.1| putative dehydrogenase [Streptomyces avermitilis MA-4680]; ZP_00187394.1| COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Rubrobacter xylanophilus DSM 9941]).; Specificity unclear; putative beta-hydroxyacid dehydrogenase 558564..559439 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175814 YP_001221221.1 CDS pyrE NC_009480.1 559506 560060 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 559506..560060 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174601 YP_001221222.1 CDS CMM_0482 NC_009480.1 560060 562135 D hypothetical protein (weak similarity to: Q06852|SLP1_CLOTM CELL SURFACE GLYCOPROTEIN 1 PRECURSOR (OUTER LAYER PROTEIN B)(S-LAYER PROTEIN 1)).; hypothetical protein 560060..562135 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174805 YP_001221223.1 CDS CMM_0483 NC_009480.1 562242 563510 D putative efflux MFS permease (ZP_00098466.1| COG0477: Permeases of the major facilitator superfamily [Desulfitobacterium hafniense]; NP_486255.1|; Specificity unclear; putative MFS permease 562242..563510 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172997 YP_001221224.1 CDS nagD NC_009480.1 563511 564308 R putative N-acetylglucosamine-6-phosphate deacetylase (ZP_00228023.1| COG0647: Predicted sugar phosphatases of the HAD superfamily [Kineococcus radiotolerans SRS30216]; NP_627072.1| putative N-acetylglucosamine-6-phosphate deacetylase [Streptomyces coelicolor A3(2)]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.; Specificity unclear; putative N-acetylglucosamine-6-phosphate deacetylase complement(563511..564308) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174205 YP_001221225.1 CDS cpdA NC_009480.1 564438 565343 D putative 3',5'-cyclic-nucleotide phosphodiesterase (ZP_00227924.1| COG1409: Predicted phosphohydrolases [Kineococcus radiotolerans SRS30216]; F70536 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) cpdA homolog -Mycobacterium tuberculosis (strain H37RV)). pfam00149,Metallophos, Calcineurin-like phosphoesterase. This family includes a diverse range of phosphoesterases.; Specificity unclear; putative 3',5'-cyclic-nucleotide phosphodiesterase 564438..565343 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173855 YP_001221226.1 CDS CMM_0486 NC_009480.1 565417 565587 R hypothetical protein (ZP_00197844.1| hypothetical protein Krad06004950 [Kineococcus radiotolerans SRS30216]; ZP_00052607.1| COG3237: Uncharacterized protein conserved in bacteria [Magnetospirillum magnetotacticum]).; hypothetical protein complement(565417..565587) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173188 YP_001221227.1 CDS CMM_0487 NC_009480.1 565772 566191 D putative membrane protein (NP_954813.1| putative membrane protein [Gordonia westfalica]; NP_628654.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; Hypothetical protein; hypothetical protein 565772..566191 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174918 YP_001221228.1 CDS recQ2 NC_009480.1 566280 568454 D putative ATP-dependent DNA helicase (NP_823626.1| putative ATP-dependent DNA helicase [Streptomyces avermitilis MA-4680]; ZP_00226231.1| COG0514: Superfamily II DNA helicase [Kineococcus radiotolerans SRS30216]). pfam00270, DEAD, DEAD/DEAH box helicase. pfam00271,Helicase_C, Helicase conserved C-terminal domain.; High confidence in function and specificity; putative ATP-dependent DNA helicase 566280..568454 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173989 YP_001221229.1 CDS CMM_0489 NC_009480.1 568474 569520 R putative adenine-specific DNA-modification methylase (NP_787899.1| DNA modification methyltransferase [Tropheryma whipplei str. Twist]; NP_085633.1| DNA methyltransferase [Mesorhizobium loti MAFF303099]). pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.; Specificity unclear; putative adenine-specific DNA-modification methylase complement(568474..569520) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174295 YP_001221230.1 CDS CMM_0490 NC_009480.1 569873 570955 D putative membrane protein,; Hypothetical protein; hypothetical protein 569873..570955 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173413 YP_001221231.1 CDS CMM_0491 NC_009480.1 571114 572013 D putative membrane protein (ZP_00060954.1| hypothetical protein [Clostridium thermocellum ATCC 27405]; NP_821188.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; hypothetical protein 571114..572013 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173903 YP_001221232.1 CDS CMM_0492 NC_009480.1 572091 573335 D conserved hypothetical protein (ZP_00227183.1| COG3844: Kynureninase [Kineococcus radiotolerans SRS30216]; ZP_00049417.2| COG3844: Kynureninase [Magnetospirillum magnetotacticum]). pfam00266,Aminotran_5, Aminotransferase class-V.; Family membership; hypothetical protein 572091..573335 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175464 YP_001221233.1 CDS CMM_0493 NC_009480.1 573369 574463 R putative NAD(P)H-dependant dehydrogenase (ZP_00226640.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_384229.1| PUTATIVE OXIDOREDUCTASE PROTEIN [Sinorhizobium meliloti 1021]). pfam01408, GFO_IDH_MocA,Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD.; Function unclear; putative oxidoreductase complement(573369..574463) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175332 YP_001221234.1 CDS CMM_0494 NC_009480.1 574662 576896 D putative sucrose synthase (Sucrose-UDP glucosyltransferase)(NP_681372.1| sucrose phosphate synthase [Thermosynechococcus elongatus BP-1]; NP_926553.1| sucrose phosphate synthase [Gloeobacter violaceus PCC 7421]; P31922|SUS1_HORVU Sucrose synthase 1 (Sucrose-UDP glucosyltransferase 1)). SUCROSE-CLEAVING ENZYME THAT PROVIDES UDP-GLUCOSE AND FRUCTOSE FOR VARIOUS METABOLIC PATHWAYS. pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Family membership; putative sucrose synthase (sucrose-UDP glucosyltransferase) 574662..576896 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175667 YP_001221235.1 CDS CMM_0495 NC_009480.1 576893 578218 D putative glucoronosyltransferase (ZP_00240271.1| macrolide glycosyltransferase [Bacillus cereus G9241]; AAM70336.1| CalG1 [Micromonospora echinospora]). InterPro: UDP-glucoronosyl and UDP-glucosyl transferase. pfam00201,UDPGT, UDP-glucoronosyl and UDP-glucosyl transferase.; Function unclear; putative glycosyltransferase 576893..578218 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173465 YP_001221236.1 CDS CMM_0496 NC_009480.1 578576 580291 D conserved hypothetical protein (CAB03747.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_925015.1| hypothetical protein gll2069 [Gloeobacter violaceus PCC 7421]). pfam04169, DUF404,Domain of unknown function (DUF404). pfam04174, DUF407,Domain of unknown function (DUF407).; hypothetical protein 578576..580291 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175276 YP_001221237.1 CDS CMM_0497 NC_009480.1 580291 581226 D conserved hypothetical protein (NP_961156.1| hypothetical protein MAP2222c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00164167.1| COG2307: Uncharacterized protein conserved in bacteria [Synechococcus elongatus PCC 7942]). pfam04168, DUF403,Bacterial domain of unknown function (DUF403).; hypothetical protein 580291..581226 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173008 YP_001221238.1 CDS CMM_0498 NC_009480.1 581223 582068 D conserved hypothetical protein (NP_961155.1| hypothetical protein MAP2221c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00213669.1| COG1305: Transglutaminase-like enzymes, putative cysteine proteases [Burkholderia cepacia R18194]). , pfam01841,Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function.; Function unclear; hypothetical protein 581223..582068 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173998 YP_001221239.1 CDS CMM_0499 NC_009480.1 582124 583041 D putative lysophospholipase (NP_622099.1| Lysophospholipase [Thermoanaerobacter tengcongensis]; NP_972747.1| hydrolase, alpha/beta fold family [Treponema denticola ATCC 35405]). InterPro: Esterase/lipase/thioesterase family active site pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative lysophospholipase 582124..583041 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175033 YP_001221240.1 CDS CMM_0500 NC_009480.1 583038 583532 D putative acetyltransferase (ZP_00109910.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Nostoc punctiforme]; NP_939442.1| Putative acetyltransferase [Corynebacterium diphtheriae]).; Function unclear; putative acetyltransferase 583038..583532 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175669 YP_001221241.1 CDS CMM_0501 NC_009480.1 583604 586429 R conserved hypothetical protein, putative cell wall/surface protein; hypothetical protein complement(583604..586429) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174047 YP_001221242.1 CDS CMM_0502 NC_009480.1 586426 588303 R putative serine protease, family S53 (NP_827126.1| hypothetical protein [Streptomyces avermitilis MA-4680]). pfam00082, Peptidase_S8, Subtilase family. Subtilases are a family of serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like that found in the trypsin serine proteases (see pfam00089).; Function unclear; serine protease complement(586426..588303) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175153 YP_001221243.1 CDS CMM_0503 NC_009480.1 588673 589404 D putative transcriptional regulator, TetR family (NP_630409.1| transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_639852.1| putative lactone-dependent transcriptional regulator (TetR-family), MmfR [Streptomyces coelicolor A3(2)]). InterPro: Bacterial regulatory proteins TetR family pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 588673..589404 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173391 YP_001221244.1 CDS CMM_0504 NC_009480.1 589476 591650 R putative non-hemolytic phospholipase C (NP_900579.1| non-hemolytic phospholipase C precursor [Chromobacterium violaceum ATCC 12472]; A36143 phospholipase C (EC 3.1.4.3), nonhemolytic - Pseudomonas aeruginosa). pfam04185, Phosphoesterase, Phosphoesterase family. This family includes both bacterial phospholipase C enzymes EC:3.1.4.3, but also eukaryotic acid phosphatases EC:3.1.3.2. pfam05506, DUF756, Domain of unknown function (DUF756). This domain is found, normally as a tandem repeat, at the C-terminus of bacterial phospholipase C proteins.; Function unclear; putative phospholipase C complement(589476..591650) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174607 YP_001221245.1 CDS alkB NC_009480.1 591934 592566 R putative alkylated DNA repair protein (NP_822306.1| putative alkylated DNA repair protein [Streptomyces avermitilis MA-4680]; NP_215515.1| Alkylated DNA repair protein [Mycobacterium tuberculosis H37Rv]). alkb: alkylated DNA repair protein AlkB; Function unclear; DNA repair system specific for alkylated DNA complement(591934..592566) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173484 YP_001221246.1 CDS CMM_0506 NC_009480.1 592631 593311 R conserved membrane protein (NP_832507.1| Integral membrane protein [Bacillus cereus ATCC 14579]; ZP_00212776.1| hypothetical protein Bcepa02005818 [Burkholderia cepacia R18194]).; Conserved hypothetical protein; hypothetical protein complement(592631..593311) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173392 YP_001221247.1 CDS lplA NC_009480.1 593390 594439 D putative lipoate-protein ligase A (ZP_00227712.1| COG0095: Lipoate-protein ligase A [Kineococcus radiotolerans SRS30216]; T46683 probable lipoate protein ligase snoP [imported] - Streptomyces nogalater). CREATES AN AMIDE LINKAGE THAT JOINS THE FREE CARBOXYL GROUP OF LIPOIC ACID TO THE EPSILON-AMINO GROUP OF A SPECIFIC LYSINE RESIDUE IN LIPOATE-DEPENDENT ENZYMES. THE ENZYME CATALYZES BOTH THE ATP-DEPENDENT ACTIVATION OF LIPOATE TO LIPOYL-AMP AND THE TRANSFER OF THE ACTIVATED LIPOYL ON THE APOPROTEINS (BY SIMILARITY). InterPro: Biotin/lipoate A/B protein ligase family lipoyltrans: lipoyltransferase and lipoate protein ligase pfam03099, BPL_LipA_LipB,Biotin/lipoate A/B protein ligase family. This family includes biotin protein ligase, lipoate-protein ligase A and B. Biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites.; Specificity unclear; putative lipoate-protein ligase A 593390..594439 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173463 YP_001221248.1 CDS CMM_0508 NC_009480.1 594698 594982 R putative acetyltransferase (NP_631766.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00225610.1| COG2388: Predicted acetyltransferase [Kineococcus radiotolerans SRS30216]).; Function unclear; putative acetyltransferase complement(594698..594982) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175060 YP_001221249.1 CDS CMM_0509 NC_009480.1 595050 595268 R hypothetical protein complement(595050..595268) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175328 YP_001221250.1 CDS CMM_0510 NC_009480.1 595269 595616 R hypothetical protein complement(595269..595616) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174154 YP_001221251.1 CDS CMM_0511 NC_009480.1 595865 596761 D conserved hypothetical protein (N-terminal: AAD27613.1| 57 kilodalton cell surface protein precursor Msa2 [Renibacterium salmoninarum]; NP_821231.1| hypothetical protein SAV57 [Streptomyces avermitilis MA-4680]). C-terminal half: NP_241888.1| BH1022~unknown conserved protein in bacilli [Bacillus halodurans C-125]; NP_828397.1| hypothetical protein SAV7221 [Streptomyces avermitilis MA-4680])., pfam01833, TIG, IPT/TIG domain.; hypothetical protein 595865..596761 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175029 YP_001221252.1 CDS CMM_0512 NC_009480.1 596758 597207 R putative membrane protein (weak similarities to: NP_656679.1| hypothetical protein predicted by GeneMark [Bacillus anthracis A2012]).; hypothetical protein complement(596758..597207) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174313 YP_001221253.1 CDS pgmA NC_009480.1 597320 598960 R catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase complement(597320..598960) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175441 YP_001221254.1 CDS pheA NC_009480.1 599010 599966 D Prephenate dehydratase (|NP_628146.1| prephenate dehydratase [Streptomyces coelicolor A3(2)]; ZP_00058942.1| COG0077: Prephenate dehydratase [Thermobifida fusca]). pfam00800, PDT, Prephenate dehydratase. This protein is involved in Phenylalanine biosynthesis. This protein catalyses the decarboxylation of prephenate to phenylpyruvate. pfam01842, ACT, ACT domain. This family of domains generally have a regulatory role. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. Pairs of ACT domains bind specifically to a particular amino acid leading to regulation of the linked enzyme.; High confidence in function and specificity; hypothetical protein 599010..599966 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174619 YP_001221255.1 CDS serS NC_009480.1 600028 601308 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 600028..601308 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174596 YP_001221256.1 CDS CMM_0516 NC_009480.1 601305 602126 D putative hydrolase (ZP_00226154.1| COG0561: Predicted hydrolases of the HAD superfamily [Kineococcus radiotolerans SRS30216]; NP_789662.1| conserved hypothetical protein [Tropheryma whipplei TW08/27]).; Function unclear; HAD family hydrolase 601305..602126 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173199 YP_001221257.1 CDS CMM_0517 NC_009480.1 602512 603657 D putative transcriptional regulator/attenuator, LytR family(NP_787856.1| transcriptional regulator [Tropheryma whipplei str. Twist]; NP_627264.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]). , pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.; Function unclear; LytR family transcriptional regulator 602512..603657 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175395 YP_001221258.1 CDS CMM_0518 NC_009480.1 604230 604763 D hypothetical protein 604230..604763 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172939 YP_001221259.1 CDS CMM_0519 NC_009480.1 604825 605892 D putative transcriptional regulator, LacI family (BAD02385.1| LacI/GalR family transcriptional repressor [Streptomyces thermoviolaceus]; NP_628912.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; hypothetical protein 604825..605892 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174209 YP_001221260.1 CDS CMM_0520 NC_009480.1 606062 606760 D conserved hypothetical protein (ZP_00226605.1| COG3828: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_624682.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; Function unclear; hypothetical protein 606062..606760 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174382 YP_001221261.1 CDS CMM_0521 NC_009480.1 606778 607854 D putative oxidoreductase/dehydrogenase (ZP_00226604.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_770032.1| dehydrogenase [Bradyrhizobium japonicum USDA 110]). pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD. InterPro: Oxidoreductase C-terminal.; Function unclear; putative oxidoreductase/dehydrogenase 606778..607854 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173863 YP_001221262.1 CDS CMM_0522 NC_009480.1 607946 608311 D hypothetical protein 607946..608311 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173101 YP_001221263.1 CDS CMM_0523 NC_009480.1 608351 609706 R glycosyl hydrolase, family 13 (NP_960521.1| hypothetical protein MAP1587c [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_737573.1| putative amylase [Corynebacterium efficiens YS-314]). InterPro: Glycoside hydrolase family 13 pfam00128, Alpha-amylase, Alpha amylase, catalytic domain.; High confidence in function and specificity; glycosyl hydrolase family protein complement(608351..609706) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174446 YP_001221264.1 CDS CMM_0524 NC_009480.1 610366 611445 R hypothetical protein complement(610366..611445) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175271 YP_001221265.1 CDS CMM_0525 NC_009480.1 611442 611858 R putative transcriptional regulator, PadR family (NP_687299.1| conserved hypothetical protein [Streptococcus agalactiae 2603V/R]; NP_422202.1| conserved hypothetical protein [Caulobacter crescentus CB15]). pfam03551, PadR, Transcriptional regulator PadR-like family. Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.; Specificity unclear; PadR family transcriptional regulator complement(611442..611858) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175740 YP_001221266.1 CDS CMM_0526 NC_009480.1 612006 612341 D hypothetical protein 612006..612341 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174485 YP_001221267.1 CDS CMM_0527 NC_009480.1 612444 613211 D putative membrane protein, possible preprotein translocase (NP_627080.1| putative membrane protein. [Streptomyces coelicolor A3(2)]; ZP_00057695.1| COG0706: Preprotein translocase subunit YidC [Thermobifida fusca]). pfam02096, 60KD_IMP, 60Kd inner membrane protein.; Conserved hypothetical protein; hypothetical protein 612444..613211 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174470 YP_001221268.1 CDS CMM_0528 NC_009480.1 613276 614184 D putative metal-dependent hydrolase (NP_796992.1| hypothetical protein VP0613 [Vibrio parahaemolyticus RIMD 2210633]; CAG19181.1| hypothetical metal-dependent hydrolase [Photobacterium profundum]).; Function unclear; putative metal-dependent hydrolase 613276..614184 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173886 YP_001221269.1 CDS CMM_0529 NC_009480.1 614297 614839 D hypothetical protein 614297..614839 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173238 YP_001221270.1 CDS CMM_0530 NC_009480.1 614857 615891 D putative oxidoreductase (ZP_00228825.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; NP_629103.1| putative aldoketoreductase [Streptomyces coelicolor A3(2)]). pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative oxidoreductase 614857..615891 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173110 YP_001221271.1 CDS plsC NC_009480.1 615988 616755 D putative 1-acylglycerol-3-phosphate O-acyltransferase (NP_822660.1| putative 1-acylglycerol-3-phosphate O-acyltransferase [Streptomyces avermitilis MA-4680]; NP_602082.1| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Corynebacterium glutamicum ATCC 13032]). , pfam01553, Acyltransferase, Acyltransferase.; Specificity unclear; putative 1-acylglycerol-3-phosphate O-acyltransferase 615988..616755 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174882 YP_001221272.1 CDS panD NC_009480.1 617075 617491 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(617075..617491) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173307 YP_001221273.1 CDS CMM_0533 NC_009480.1 617722 618813 D putative tRNA processing ribonuclease BN (RNase BN)(NP_822167.1| putative membrane protein [Streptomyces avermitilis MA-4680]; BAB98344.1| tRNA-processing ribonuclease BN [Corynebacterium glutamicum ATCC 13032]). rbn: ribonuclease BN putative pfam03631, Ribonuclease_BN,Ribonuclease BN-like family. This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation.; Function unclear; putative tRNA processing ribonuclease BN 617722..618813 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175419 YP_001221274.1 CDS phrB NC_009480.1 618856 620382 R putative deoxyribodipyrimidine photolyase (NP_108272.1| blue light photoreceptor cryptochrome [Mesorhizobium loti MAFF303099]; NP_531913.1| DNA photolyase [Agrobacterium tumefaciens str. C58]). pfam00875, DNA_photolyase, DNA photolyase. This domain binds a light harvesting cofactor. pfam03441,FAD_binding_7, FAD binding domain of DNA photolyase.; High confidence in function and specificity; deoxyribodipyrimidine photo-lyase complement(618856..620382) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173469 YP_001221275.1 CDS CMM_0535 NC_009480.1 620529 621914 D putative glycosyl transferase (weak similarities to: NP_787164.1| glycosyltransferase [Tropheryma whipplei str. Twist]; NP_808963.1| putative glycosyltransferase [Bacteroides thetaiotaomicron VPI-5482]) pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Hypothetical protein; putative glycosyl transferase 620529..621914 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173746 YP_001221276.1 CDS CMM_0536 NC_009480.1 621911 622354 R transcriptional regulator, MarR family (NP_103003.1| probable transcriptional regulator [Mesorhizobium loti MAFF303099]; NP_631765.1| putative marR-family regulatory protein [Streptomyces coelicolor A3(2)]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator complement(621911..622354) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175522 YP_001221277.1 CDS CMM_0537 NC_009480.1 622675 623469 R putative transcriptional regulator (NP_213217.1| transcriptional regulator (PhoB-like) [Aquifex aeolicus]; NP_831082.1| Two-component response regulator [Bacillus cereus ATCC 14579]; NP_627031.1| putative two component system response regulator [Streptomyces coelicolor A3(2)]). pfam00486, Trans_reg_C, Transcriptional regulatory protein, C terminal.; Specificity unclear; putative transcriptional regulator complement(622675..623469) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173456 YP_001221278.1 CDS upp NC_009480.1 623866 624504 R uppA; Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(623866..624504) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173050 YP_001221279.1 CDS CMM_0539 NC_009480.1 624573 625022 D putative cytosine/adenosine deaminase (ZP_00225554.1| COG0590: Cytosine/adenosine deaminases [Kineococcus radiotolerans SRS30216]; NP_825357.1| putative deaminase [Streptomyces avermitilis MA-4680]). pfam00383, dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region.; High confidence in function and specificity; putative cytosine/adenosine deaminase 624573..625022 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173149 YP_001221280.1 CDS CMM_0540 NC_009480.1 625050 625583 R conserved hypothetical prtotein (NP_624782.1| conserved hypothetical protein SCF76.03 [Streptomyces coelicolor A3(2)]; NP_830758.1| hypothetical protein [Bacillus cereus ATCC 14579]). pfam07336, DUF1470, Protein of unknown function (DUF1470). COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding [General function prediction only]; hypothetical protein complement(625050..625583) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175494 YP_001221281.1 CDS CMM_0541 NC_009480.1 625636 626043 D Region created by contig update; putative carboxymuconolactone decarboxylase-like protein 625636..626043 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174292 YP_001221282.1 CDS CMM_0542 NC_009480.1 626040 626948 D putative phosphotriesterase-family protein (NP_625331.1| putative phosphotriesterase-family protein [Streptomyces coelicolor A3(2)]; NP_465494.1|; Function unclear; putative phosphotriesterase-family protein 626040..626948 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173072 YP_001221283.1 CDS CMM_0543 NC_009480.1 626945 627862 R putative metal efflux transport protein, CDF family (NP_826229.1| putative transport protein [Streptomyces avermitilis MA-4680]; ZP_00109098.1| COG0053: Predicted Co/Zn/Cd cation transporters [Nostoc punctiforme]). pfam01545, Cation_efflux, Cation efflux family. Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.; Specificity unclear; CDF family metal efflux transport protein complement(626945..627862) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173377 YP_001221284.1 CDS proC NC_009480.1 627994 628869 D pyrroline-5-carboxylate reductase (ZP_00057049.1| COG0345: Pyrroline-5-carboxylate reductase [Thermobifida fusca]; NP_737040.1| pyrroline-5-carboxylate reductase [Corynebacterium efficiens YS-314]). proC: pyrroline-5-carboxylate reductase pfam01089, P5CR, Delta 1-pyrroline-5-carboxylate reductase.; High confidence in function and specificity; hypothetical protein 627994..628869 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173415 YP_001221285.1 CDS trkA NC_009480.1 628910 629578 R putative K+ transporter, Trk family, NAD-binding component (ZP_00058665.1| COG0569: K+ transport systems,NAD-binding component [Thermobifida fusca]; ZP_00096571.1| COG0569: K+ transport systems, NAD-binding component [Novosphingobium aromaticivorans]). , pfam02254,TrkA_N, TrkA-N domain. This domain is found in a wide variety of proteins., pfam02080, TrkA_C, TrkA-C domain.; High confidence in function and specificity; potassium uptake system NAD-binding protein complement(628910..629578) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175803 YP_001221286.1 CDS trkG NC_009480.1 629643 631067 R putative K+-transporter, membrane component; Trk family (ZP_00226587.1| COG0168: Trk-type K+ transport systems, membrane components [Kineococcus radiotolerans SRS30216]; ZP_00058666.1| COG0168: Trk-type K+ transport systems, membrane components [Thermobifida fusca]). InterPro: Cation transport protein pfam02386, TrkH, Cation transport protein. TIGRFAM (TIGR00933): K+ Transporter (Trk) Family pro; High confidence in function and specificity; Trk family potassium uptake protein complement(629643..631067) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175214 YP_001221287.1 CDS CMM_0547 NC_009480.1 631147 631695 D transcriptional regulator, ArsR family (NP_898749.1| putative ArsR-family regulator [Rhodococcus erythropolis]; NP_630901.1| putative ArsR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam01022, HTH_5, Bacterial regulatory protein,arsR family. Members of this family contains a DNA binding 'helix-turn-helix' motif.; Specificity unclear; ArsR family transcriptional regulator 631147..631695 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175368 YP_001221288.1 CDS CMM_0548 NC_009480.1 631818 632057 D putative DNA-binding protein, putative excisionase (NP_825908.1| hypothetical protein SAV4731 [Streptomyces avermitilis MA-4680]; NP_334930.1| excisionase, putative [Mycobacterium tuberculosis CDC1551]). InterPro: Bacterial regulatory protein LacI family , weak similarity to: COG3311, AlpA, Predicted transcriptional regulator [Transcription].; Function unclear; putative DNA-binding protein excisionase 631818..632057 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173296 YP_001221289.1 CDS serB1 NC_009480.1 632357 633196 R putative phosphoserine phosphatase (CAB55344.1| phosphoserine phosphatase [Streptomyces coelicolor A3(2)]; ZP_00227480.1| COG0560: Phosphoserine phosphatase [Kineococcus radiotolerans SRS30216]). InterPro: Haloacid dehalogenase/epoxide hydrolase family serB: phosphoserine phosphatase SerB. pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.; High confidence in function and specificity; putative phosphoserine phosphatase complement(632357..633196) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173062 YP_001221290.1 CDS CMM_0550 NC_009480.1 633187 633450 D putative thioredoxin (ZP_00227479.1| COG0526: Thiol-disulfide isomerase and thioredoxins [Kineococcus radiotolerans SRS30216]; CAB00934.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). redox_disulf_1: redox-active disulfide; Function unclear; putative thioredoxin 633187..633450 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175250 YP_001221291.1 CDS CMM_0551 NC_009480.1 633485 633787 D Region created by contig update; hypothetical protein 633485..633787 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173187 YP_001221292.1 CDS CMM_0552 NC_009480.1 633849 634880 D putative transcriptional regulator, LacI family (CAC49322.1| putative transcriptional regulator, LacI family protein [Sinorhizobium meliloti]; B65179 ribose operon repressor - Escherichia coli (strain K-12)). InterPro: Periplasmic binding proteins and sugar binding domain LacI family pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; LacI family transcriptional regulator 633849..634880 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173242 YP_001221293.1 CDS CMM_0553 NC_009480.1 634993 636306 D putative sugar MFS permease (CAD47863.1| putative inositol transport protein [Arthrobacter nicotinovorans]; NP_786681.1| sugar transport protein [Lactobacillus plantarum WCFS1]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative sugar MFS-permease 634993..636306 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173736 YP_001221294.1 CDS CMM_0554 NC_009480.1 636303 637142 D putative hydrolase (NP_350247.1| Alpha/beta superfamily hydrolase [Clostridium acetobutylicum ATCC 824]; NP_623397.1| Hydrolases of the alpha/beta superfamily [Thermoanaerobacter tengcongensis]). InterPro: Esterase/lipase/thioesterase family active site pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase 636303..637142 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173093 YP_001221295.1 CDS CMM_0555 NC_009480.1 637139 638380 D conserved hypothetical protein (NP_624916.1| conserved hypothetical protein SCF55.28c [Streptomyces coelicolor A3(2)]; NP_601589.2| hypothetical protein NCgl2305 [Corynebacterium glutamicum ATCC13032]).; Function unclear; hypothetical protein 637139..638380 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173410 YP_001221296.1 CDS CMM_0556 NC_009480.1 638377 639012 R putative membrane protein (NP_978925.1| membrane protein, putative [Bacillus cereus ATCC 10987]; ZP_00228655.1| hypothetical protein Krad06001037 [Kineococcus radiotolerans SRS30216]).; hypothetical protein complement(638377..639012) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173020 YP_001221297.1 CDS CMM_0557 NC_009480.1 639092 639307 R hypothetical protein complement(639092..639307) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173335 YP_001221298.1 CDS CMM_0558 NC_009480.1 639386 639718 R hypothetical protein complement(639386..639718) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173576 YP_001221299.1 CDS CMM_0559 NC_009480.1 639896 640306 R hypothetical protein complement(639896..640306) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173967 YP_001221300.1 CDS CMM_0560 NC_009480.1 640299 641534 R putative transcriptional regulator (NP_787856.1| transcriptional regulator [Tropheryma whipplei str. Twist]; ZP_00058848.1| COG1316: Transcriptional regulator [Thermobifida fusca]). lytR_cpsA_psr: cell envelope-related fu pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.; Specificity unclear; putative transcriptional regulator complement(640299..641534) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172942 YP_001221301.1 CDS aspS NC_009480.1 641710 643020 R Aspartyl-tRNA synthetase (Aspartate-tRNA ligase) (NP_789687.1| aspartyl-tRNA synthetase [Tropheryma whipplei TW08/27]; NP_831934.1| Aspartyl-tRNA synthetase [Bacillus cereus ATCC 14579]). pfam01336, tRNA_anti, OB-fold nucleic acid binding domain. This family contains OB-fold domains that bind to nucleic acids. The family includes the anti-codon binding domain of lysyl, aspartyl,and asparaginyl-tRNA synthetases (See pfam00152). pfam00152, tRNA-synt_2, tRNA synthetases class II (D, K and N).; High confidence in function and specificity; aspartyl-tRNA synthetase complement(641710..643020) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173604 YP_001221302.1 CDS CMM_0562 NC_009480.1 643133 643966 D conserved hypothetical protein (ZP_00059424.1| COG1540: Uncharacterized proteins, homologs of lactam utilization protein B [Thermobifida fusca]; Q7MZI3|Y7A4_PHOLL Hypothetical UPF0271 protein plu4304). pfam03746, LamB_YcsF, LamB/YcsF family. The exact molecular function of the proteins in this family is unknown.; Function unclear; hypothetical protein 643133..643966 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174971 YP_001221303.1 CDS CMM_0563 NC_009480.1 643963 644583 D putative allophanate hydrolase subunit (NP_534404.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]; ZP_00125164.1| COG1984: Allophanate hydrolase subunit 2 [Pseudomonas syringae pv. syringae B728a]). pfam02682, AHS1,Allophanate hydrolase subunit 1.; Function unclear; putative allophanate hydrolase subunit 643963..644583 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172958 YP_001221304.1 CDS CMM_0564 NC_009480.1 644580 645497 D putative allophanate hydrolase subunit 2 (ZP_00059426.1| COG1984: Allophanate hydrolase subunit 2 [Thermobifida fusca]; ZP_00168285.1| COG1984: Allophanate hydrolase subunit 2 [Ralstonia eutropha JMP134]). pfam02626, AHS2, Allophanate hydrolase subunit 2. This domain forms the second subunit of allophanate hydrolase.; Specificity unclear; putative allophanate hydrolase subunit 644580..645497 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172926 YP_001221305.1 CDS CMM_0565 NC_009480.1 645549 646376 R putative membrane protein (NP_822890.1| hypothetical protein SAV1714 [Streptomyces avermitilis MA-4680]; ZP_00228318.1| COG1714: Predicted membrane protein/domain [Kineococcus radiotolerans SRS30216]).; hypothetical protein complement(645549..646376) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172968 YP_001221306.1 CDS CMM_0566 NC_009480.1 646496 648985 R putative excinuclease ABC subunit, UvrA paralog (NP_625216.1| putative excinuclease ABC subunit A [Streptomyces coelicolor A3(2)]; ZP_00226049.1| COG0178: Excinuclease ATPase subunit [Kineococcus radiotolerans SRS30216]). The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB the uvrA molecules dissociate (By similarity).; Function unclear; putative excinuclease ABC subunit A complement(646496..648985) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172979 YP_001221307.1 CDS sigB NC_009480.1 649537 650580 R putative RNA polymerase sigma 70 factor (subfamily principal sigma factors) , InterPro: Sigma-70 factor family., pfam00140, Sigma70_r1_2, Sigma-70 factor, region 1.2., pfam04542, Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. , pfam04539, Sigma70_r3, Sigma-70 region 3. ,pfam04545, Sigma70_r4, Sigma-70, region 4.; Specificity unclear; putative RNA polymerase sigma 70 factor complement(649537..650580) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173006 YP_001221308.1 CDS CMM_0568 NC_009480.1 650896 651540 D putative phosphoglycerate mutase (NP_787883.1| phosphoglycerate mutase [Tropheryma whipplei str. Twist]; NP_628636.1| putative phosphoglycerate mutase [Streptomyces coelicolor A3(2)]). pfam00300, PGAM,Phosphoglycerate mutase family.; Specificity unclear; putative phosphoglycerate mutase 650896..651540 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175818 YP_001221309.1 CDS ccbD NC_009480.1 651540 652148 D putative thioredoxin, maybe involved in cytochrome C biogenesis (AAS20117.1| hypothetical protein [Arthrobacter aurescens]; ZP_00227205.1| COG0526: Thiol-disulfide isomerase and thioredoxins [Kineococcus radiotolerans SRS30216])., , InterPro: Thioredoxin, dsbE: periplasmic protein thiol:disulfide; Specificity unclear; putative thioredoxin 651540..652148 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172989 YP_001221310.1 CDS ccdA NC_009480.1 652149 652889 D Cytochrome c-type biogenesis protein, membrane component (AAS20063.1| cytochrome biogenesis related protein [Arthrobacter aurescens]; NP_825976.1| putative cytochrome C biogenesis membrane protein [Streptomyces avermitilis MA-4680]). , , pfam02683, DsbD, Cytochrome C biogenesis protein transmembrane region. This family consists of the transmembrane (i.e. non-catalytic) region of Cytochrome C biogenesis proteins also known as disulphide interchange proteins.; High confidence in function and specificity; cytochrome C biogenesis membrane protein 652149..652889 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173561 YP_001221311.1 CDS resB NC_009480.1 652873 654519 D putative cytochrome C biogenesis membrane protein (AAS20089.1| putative cytochrome c biogenesis membrane protein [Arthrobacter aurescens]; ZP_00227402.1| COG1333: ResB protein required for cytochrome c biosynthesis [Kineococcus radiotolerans SRS30216]). , , pfam05140,ResB, ResB-like family. This family includes both ResB and cytochrome c biogenesis proteins.; High confidence in function and specificity; putative cytochrome C biogenesis membrane protein 652873..654519 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173680 YP_001221312.1 CDS resC NC_009480.1 654516 655541 D putative cytochrome c biogenesis protein, ABC transporter ATPase component(NP_789692.1| putative cytochrome biogenesis protein [Tropheryma whipplei TW08/27]; AAS20090.1| cytochrome biogenesis protein [Arthrobacter aurescens]). , , pfam01578, Cytochrom_C_asm,Cytochrome C assembly protein.; High confidence in function and specificity; putative cytochrome C-type biogenesis protein 654516..655541 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174493 YP_001221313.1 CDS menC NC_009480.1 655571 656554 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(655571..656554) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174571 YP_001221314.1 CDS CMM_0574 NC_009480.1 656631 657806 D putative cytosine-specific DNA methylase (NP_927946.1| hypothetical protein [Photorhabdus luminescens subsp. laumondii TTO1]; NP_422420.1| DNA-cytosine methyltransferase [Caulobacter crescentus CB15]). , , pfam00145, DNA_methylase, C-5 cytosine-specific DNA methylase.; Specificity unclear; putative cytosine-specific DNA methylase 656631..657806 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174924 YP_001221315.1 CDS CMM_0575 NC_009480.1 657850 658593 D hypothetical protein, , weak similarity to: pfam01541, GIY-YIG, GIY-YIG catalytic domain. This domain called GIY-YIG is found in the amino terminal region of excinuclease abc subunit c (uvrC), bacteriophage T4 endonucleases segA, segB, segC, segD and segE; it is also found in putative endonucleases encoded by group I introns of fungi and phage.; hypothetical protein 657850..658593 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173023 YP_001221316.1 CDS menB NC_009480.1 658675 659586 D catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 658675..659586 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173042 YP_001221317.1 CDS menE NC_009480.1 659612 660799 D O-succinylbenzoate-CoA ligase (NP_789066.1| O-succinylbenzoic acid--CoA ligase [Tropheryma whipplei TW08/27]; NP_599697.1| o-succinylbenzoate-CoA ligase [Corynebacterium glutamicum ATCC 13032]). Involved in menaquinone biosynthesis. pfam00501, AMP-binding, AMP-binding enzyme.; High confidence in function and specificity; O-succinylbenzoate--CoA ligase 659612..660799 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174090 YP_001221318.1 CDS CMM_0578 NC_009480.1 660845 661828 R putative quinone oxidoreductase (NADPH:quinone reductase) (ZP_00137648.1| hypothetical protein Paer021788 [Pseudomonas aeruginosa UCBPP-PA14]; NP_721489.1| putative oxidoreductase [Streptococcus mutans UA159]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; putative quinone reductase complement(660845..661828) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175618 YP_001221319.1 CDS CMM_0579 NC_009480.1 661825 662256 R putative transcriptional regulator, MarR family (NP_627620.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_800796.1| putative transcriptional regulator [Vibrio parahaemolyticus RIMD 2210633]). pfam01047, MarR, MarR family.; Specificity unclear; MarR family transcriptional regulator complement(661825..662256) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173076 YP_001221320.1 CDS CMM_0580 NC_009480.1 662376 662798 D putative ester cyclase (XP_386716.1| hypothetical protein FG06540.1 [Gibberella zeae PH-1]; NP_825174.1| hypothetical protein SAV3997 [Streptomyces avermitilis MA-4680]; ZP_00227684.1| COG5485: Predicted ester cyclase [Kineococcus radiotolerans SRS30216]).; hypothetical protein 662376..662798 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173047 YP_001221321.1 CDS CMM_0581 NC_009480.1 662903 663076 R hypothetical protein (ZP_00161537.1| COG3237: Uncharacterized protein conserved in bacteria [Anabaena variabilis ATCC 29413]); hypothetical protein complement(662903..663076) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173099 YP_001221322.1 CDS CMM_0582 NC_009480.1 663209 663526 D putative membrane protein (NP_600566.1| hypothetical membrane protein [Corynebacterium glutamicum ATCC 13032]).; Hypothetical protein; hypothetical protein 663209..663526 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173057 YP_001221323.1 CDS CMM_0583 NC_009480.1 663516 663911 R putative NTP pyrophosphohydrolase (ZP_00292530.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Thermobifida fusca]; CAG22608.1| hypothetical protein [Photobacterium profundum]). pfam00293, NUDIX, NUDIX domain.; Function unclear; putative NTP pyrophosphohydrolase complement(663516..663911) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173150 YP_001221324.1 CDS CMM_0584 NC_009480.1 664071 664676 R putative acetyltransferase (NP_821878.1| putative acetyltransferase [Streptomyces avermitilis MA-4680]; NP_535242.1| acetyltransferase [Agrobacterium tumefaciens str. C58]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(664071..664676) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173112 YP_001221325.1 CDS CMM_0585 NC_009480.1 664690 665268 R putative acetyltransferase (NP_821878.1| putative acetyltransferase [Streptomyces avermitilis MA-4680]; NP_535242.1| acetyltransferase [Agrobacterium tumefaciens str. C58]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(664690..665268) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173164 YP_001221326.1 CDS hemA NC_009480.1 665325 666644 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(665325..666644) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173135 YP_001221327.1 CDS hemE NC_009480.1 666749 667876 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 666749..667876 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173709 YP_001221328.1 CDS hemY NC_009480.1 667869 669308 D protoporphyrinogen oxidase (YP_055020.1| putative protoporphyrinogen oxidase, HemY [Propionibacterium acnes KPA171202]; ZP_00294157.1| COG1232: Protoporphyrinogen oxidase [Thermobifida fusca]). InterPro: Protoporphyrinogen oxidase proto_IX_ox: protoporphyrinogen oxidase domain; High confidence in function and specificity; hypothetical protein 667869..669308 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173265 YP_001221329.1 CDS CMM_0589 NC_009480.1 669436 669777 D conserved hypothetical protein (ZP_00226603.1| hypothetical protein Krad06003057 [Kineococcus radiotolerans SRS30216]; ZP_00293622.1| COG1179: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Thermobifida fusca]).; Function unclear; hypothetical protein 669436..669777 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173206 YP_001221330.1 CDS CMM_0590 NC_009480.1 669810 670226 D conserved membrane protein (ZP_00226140.1| hypothetical protein Krad06003872 [Kineococcus radiotolerans SRS30216]; NP_827521.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). pfam07332, DUF1469, Protein of unknown function (DUF1469). This family consists of several hypothetical bacterial proteins of around 140 residues in length. Members of the family seem to be found exclusively in Actinomycetes. The function of this family is unknown.; Conserved hypothetical protein; hypothetical protein 669810..670226 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173184 YP_001221331.1 CDS CMM_0591 NC_009480.1 670216 670491 D hypothetical protein 670216..670491 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173193 YP_001221332.1 CDS CMM_0592 NC_009480.1 670513 672150 D conserved membrane protein (NP_960846.1| hypothetical protein MAP1912 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_822488.1| hypothetical protein SAV1313 [Streptomyces avermitilis MA-4680]).; Conserved hypothetical protein; hypothetical protein 670513..672150 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173226 YP_001221333.1 CDS CMM_0593 NC_009480.1 672238 672801 D conserved hypothetical protein (NP_823314.1| hypothetical protein SAV2138 [Streptomyces avermitilis MA-4680]; CAB03711.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). menD: 2-succinyl-6-hydroxy-24-cyclohexad; hypothetical protein 672238..672801 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173211 YP_001221334.1 CDS CMM_0594 NC_009480.1 672863 673642 D conserved hypothetical protein (NP_630152.1| conserved hypothetical protein SC1B5.02 [Streptomyces coelicolor A3(2)]; ZP_00294158.1| COG3253: Uncharacterized conserved protein [Thermobifida fusca]). pfam06778, Chlor_dismutase, Chlorite dismutase. This family contains chlorite dismutase enzymes of bacterial and archaeal origin. This enzyme catalyses the disproportionation of chlorite into chloride and oxygen. Note that many family members are hypothetical proteins.; hypothetical protein 672863..673642 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173244 YP_001221335.1 CDS hemH NC_009480.1 673642 674892 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 673642..674892 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173261 YP_001221336.1 CDS hemC NC_009480.1 674889 675875 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 674889..675875 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175406 YP_001221337.1 CDS hemD NC_009480.1 675872 676711 D uroporphyrinogen-III synthase (NP_787859.1| uroporphyrinogen-III synthase-like protein [Tropheryma whipplei str. Twist]; CAD48147.1| uroporphyrinogen III synthase [Bacillus megaterium]). pfam02602, HEM4,Uroporphyrinogen-III synthase HemD. InterPro: Uroporphyrinogen III synthase HEM4; High confidence in function and specificity; hypothetical protein 675872..676711 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175728 YP_001221338.1 CDS hemB NC_009480.1 676708 677688 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 676708..677688 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175384 YP_001221339.1 CDS hemL NC_009480.1 677771 679138 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 677771..679138 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175293 YP_001221340.1 CDS CMM_0600 NC_009480.1 679197 680018 R putative DNA/RNA endonuclease (ZP_00227350.1| COG1864: DNA/RNA endonuclease G, NUC1 [Kineococcus radiotolerans SRS30216]; NP_792286.1| DNA/RNA non-specific endonuclease [Pseudomonas syringae pv. tomato str. DC3000]). pfam01223, Endonuclease_NS, DNA/RNA non-specific endonuclease.; Function unclear; DNA/RNA endonuclease complement(679197..680018) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175493 YP_001221341.1 CDS hemO NC_009480.1 680102 680764 R putative heme oxygenase (decyclizing) (ZP_00292306.1| COG5398: Heme oxygenase [Thermobifida fusca]; NP_827107.1| putative heme oxygenase [Streptomyces avermitilis MA-4680]). cd00232, HemeO, Heme oxygenase catalyzes the rate limiting step in the degradation of heme to bilirubin, it is essential for recycling of iron from heme. Heme is used as a substrate and cofactor for its own degradation to biliverdin, iron,and carbon monoxide. InterPro: Heme oxygenase.; High confidence in function and specificity; Heme oxygenase complement(680102..680764) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173306 YP_001221342.1 CDS CMM_0602 NC_009480.1 680840 681232 R conserved membrane protein (ZP_00226497.1| COG3759: Predicted membrane protein [Kineococcus radiotolerans SRS30216]; NP_602268.1| hypothetical membrane protein [Corynebacterium glutamicum ATCC 13032]). pfam06993,DUF1304, Protein of unknown function (DUF1304). This family consists of several hypothetical bacterial proteins of around 120 residues in length. The function of this family is unknown.; Function unclear; hypothetical protein complement(680840..681232) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174132 YP_001221343.1 CDS CMM_0603 NC_009480.1 681317 682342 R putative Zinc-dependant oxidoreductase/dehydrogenase (NP_601737.1| putative Zn-NADPH:quinone dehydrogenase [Corynebacterium glutamicum ATCC 13032]; ZP_00272074.1| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases [Ralstonia metallidurans CH34]). pfam00107, ADH_zinc_N,Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily; Function unclear; putative Zinc-dependent oxidoreductase complement(681317..682342) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173272 YP_001221344.1 CDS pfkA NC_009480.1 682375 683400 R 6-phosphofructokinase (fructose 6-phosphate 1-phosphotransferase) (ZP_00293787.1| COG0205: 6-phosphofructokinase [Thermobifida fusca]; PFP_AMYME Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (6-phosphofructokinase, pyrophosphate dependent)(Pyrophosphate-dependent 6-phosphofructose-1-kinase)(PPi-dependent phosphofructokinase)). cd00763,Bacterial_PFK, Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate.; Specificity unclear; hypothetical protein complement(682375..683400) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173314 YP_001221345.1 CDS CMM_0605 NC_009480.1 683439 684146 D kinase of unknown specificity (NP_733512.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00226595.1| COG1072: Panthothenate kinase [Kineococcus radiotolerans SRS30216]). may be Uridine kinase (EC 2.7.1.48) (Uridine monophosphokinase) (Cytidine monophosphokinase) COG0572, Udk, Uridine kinase [Nucleotide transport and metabolism], or Pantothenate kinase (EC 2.7.1.33). pfam00485, PRK, Phosphoribulokinase / Uridine kinase family. InterPro: ATP/GTP-binding site motif A (P-loop); Specificity unclear; putative kinase 683439..684146 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174902 YP_001221346.1 CDS CMM_0606 NC_009480.1 684157 684657 R putative general stress protein (NP_637057.1| general stress protein [Xanthomonas campestris pv. campestris str. ATCC 33913]; NP_294870.1| general stress protein 26, putative [Deinococcus radiodurans R1]). pfam01243, Pyridox_oxidase, Pyridoxamine 5'-phosphate oxidase.; Function unclear; putative general stress protein complement(684157..684657) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173298 YP_001221347.1 CDS CMM_0607 NC_009480.1 684723 685688 D putative DNA repair protein, putative DNA glycosylase (CAB07048.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_627260.1| conserved hypothetical protein SCE34.20 [Streptomyces coelicolor A3(2)]). pfam00730, HhH-GPD, HhH-GPD superfamily base excision DNA repair protein. This family contains a diverse range of structurally related DNA repair proteins.; Function unclear; putative DNA repair protein 684723..685688 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173328 YP_001221348.1 CDS CMM_0608 NC_009480.1 685740 686546 R Region start changed from 686564 to 686546 (-18 bases); hypothetical protein complement(685740..686546) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173342 YP_001221349.1 CDS CMM_0609 NC_009480.1 686616 687569 D putative aldose-1-epimerase (NP_696523.1| hypothetical protein with possible aldose-1-epimerase domain [Bifidobacterium longum NCC2705]; YP_055725.1| putative aldose-1-epimerase [Propionibacterium acnes KPA171202]). pfam01263, Aldose_epim, Aldose 1-epimerase.; Specificity unclear; putative aldose-1-epimerase 686616..687569 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173369 YP_001221350.1 CDS CMM_0610 NC_009480.1 687668 688135 D conserved hypothetical protein (ZP_00198752.1| COG0346: Lactoylglutathione lyase and related lyases [Kineococcus radiotolerans SRS30216]; ZP_00293658.1| COG0346: Lactoylglutathione lyase and related lyases [Thermobifida fusca]). pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Family membership; putative glyoxylase family protein 687668..688135 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173383 YP_001221351.1 CDS CMM_0611 NC_009480.1 688242 688700 D putative transcriptional regulator, MarR family (NP_801192.1| transcriptional regulator, MarR family [Vibrio parahaemolyticus RIMD 2210633]; ZP_00058332.1| COG1846: Transcriptional regulators [Thermobifida fusca]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 688242..688700 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173400 YP_001221352.1 CDS CMM_0612 NC_009480.1 688722 689468 R hypothetical protein complement(688722..689468) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173428 YP_001221353.1 CDS sacC NC_009480.1 689561 691201 R putative levanase (26-beta-D-fructan fructanohydrolase) (XP_386627.1| hypothetical protein FG06451.1 [Gibberella zeae PH-1]; NP_348398.1| Levanase [Clostridium acetobutylicum ATCC 824]; BAC54106.1| 2,6-beta-D-fructan-6-levanbiohydrolase [Streptomyces exfoliatus]). pfam00251, Glyco_hydro_32, Glycosyl hydrolases family 32. InterPro: Glycoside hydrolase family 32 pfam00251, Glyco_hydro_32, Glycosyl hydrolases family 32.; Specificity unclear; putative levanase/invertase complement(689561..691201) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173409 YP_001221354.1 CDS sacB NC_009480.1 691469 693034 D putative levansucrase (Beta-D-fructofuranosyl transferase) (BAB72022.1| beta-fructofuranosidase [Arthrobacter sp. K-1]; AAB36606.1| levansucrase precursor [Gluconacetobacter diazotrophicus]). RELEASES FRUCTOOLIGOSACCHARIDES AND LEVAN A HIGH- MOLECULAR-MASS FRUCTOSYL POLYMER FROM SUCROSE. IT ACTS MORE AS A SUCROSE HYDROLASE THAN AS A FRUCTAN POLYMERASE. pfam02435,Glyco_hydro_68, Levansucrase/Invertase. This Pfam family consists of the glycosyl hydrolase 68 family, including several bacterial levansucrase enzymes, and invertase from zymomonas.; High confidence in function and specificity; putative levansucrase 691469..693034 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175412 YP_001221355.1 CDS CMM_0615 NC_009480.1 693118 693771 D hypothetical membrane protein (NP_625282.1| putative integral membrane protein [Streptomyces coelicolor A3(2)], ZP_00057087.1| hypothetical protein [Thermobifida fusca]).; hypothetical protein 693118..693771 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173947 YP_001221356.1 CDS CMM_0616 NC_009480.1 693943 694707 D conserved hypothetical protein (NP_823510.1| hypothetical protein SAV2334 [Streptomyces avermitilis MA-4680]; ZP_00227010.1| hypothetical protein Krad06002197 [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein 693943..694707 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173468 YP_001221357.1 CDS CMM_0617 NC_009480.1 694704 695531 D conserved hypothetical protein, putative copper resistance protein (NP_789674.1| putative membrane protein [Tropheryma whipplei TW08/27]; ZP_00059215.1| COG2372: Uncharacterized protein, homolog of Cu resistance protein CopC [Thermobifida fusca]). pfam04234, CopC, Copper resistance protein CopC. CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule. Along with CopA, CopC mediates copper resistance by sequestration of copper in the periplasm.; Function unclear; hypothetical protein 694704..695531 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173437 YP_001221358.1 CDS CMM_0618 NC_009480.1 695606 696508 R putative transcriptional regulator, LysR-family (NP_599842.1| transcriptional regulator [Corynebacterium glutamicum ATCC 13032]; AAO65784.1| hypothetical DNA binding protein; SCN_3 [Streptomyces cinnamonensis]). pfam03466, LysR_substrate, LysR substrate binding domain. The structure of this domain is known and is; Specificity unclear; LysR family transcriptional regulator complement(695606..696508) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173511 YP_001221359.1 CDS putA NC_009480.1 696681 700331 D bifunctional protein [Includes: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C dehydrogenase)] (YP_055334.1| NAD-dependent aldehyde dehydrogenases [Propionibacterium acnes KPA171202]; CAF18667.1| PROLINE DEHYDROGENASE/DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE [Corynebacterium glutamicum ATCC 13032]). , pfam01619, Pro_dh, Proline dehydrogenase. ,pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor.; High confidence in function and specificity; delta-1-pyrroline-5-carboxylate dehydrogenase /proline oxidase 696681..700331 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173448 YP_001221360.1 CDS CMM_0620 NC_009480.1 700353 700484 D hypothetical protein 700353..700484 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174664 YP_001221361.1 CDS CMM_0621 NC_009480.1 700481 701185 D hypothetical protein 700481..701185 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173537 YP_001221362.1 CDS CMM_0622 NC_009480.1 701209 701787 D putative 4'-phosphopantetheinyl transferase (NP_832074.1| 4'-phosphopantetheinyl transferase [Bacillus cereus ATCC 14579]; NP_824369.1| putative phosphopantetheinyl transferase [Streptomyces avermitilis MA-4680]).; Specificity unclear; putative 4'-phosphopantetheinyl transferase 701209..701787 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173496 YP_001221363.1 CDS CMM_0623 NC_009480.1 701792 703105 R putative metalloendopeptidase, family M1 (NP_827808.1| putative metallopeptidase [Streptomyces avermitilis MA-4680]; NP_938746.1| Putative metallopeptidase [Corynebacterium diphtheriae NCTC 13129]). pfam01433, Peptidase_M1, Peptidase family M1. Members of this family are aminopeptidases.; Function unclear; metalloendopeptidase family M1 complement(701792..703105) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173562 YP_001221364.1 CDS npsC NC_009480.1 703102 707304 R non-ribosomal peptide synthase (CAF20734.1| NON-RIBOSOMAL PEPTIDE SYNTHETASE [Corynebacterium glutamicum ATCC 13032]; NP_827809.1| putative non-ribosomal peptide synthetase [Streptomyces avermitilis MA-4680]). domains: pfam00501, AMP-binding, AMP-binding enzyme; pfam00550, PP-binding, Phosphopantetheine attachment site. 2x COG0663,PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily.; Specificity unclear; non-ribosomal peptide synthase complement(703102..707304) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173570 YP_001221365.1 CDS CMM_0625 NC_009480.1 707376 707744 R putative transcriptional regulator, GntR family (NP_626001.1| putative gntR-family transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00057983.1| COG1725: Predicted transcriptional regulators [Thermobifida fusca]). pfam00392, GntR, Bacterial regulatory proteins, gntR family. This domain comprises the N-terminal HTH-containing region of GntR-like bacterial transcription factors. At the C terminus there is usually an effector-binding/oligomerisation domain.; Specificity unclear; hypothetical protein complement(707376..707744) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173739 YP_001221366.1 CDS CMM_0626 NC_009480.1 707868 708239 D Hypothetical protein; hypothetical protein 707868..708239 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173609 YP_001221367.1 CDS CMM_0627 NC_009480.1 709446 716102 D putative cell-wall associated protein (ZP_00230281.1| wall-associated protein, putative [Listeria monocytogenes str. 4b H7858]; NP_977523.1| wall associated protein, putative [Bacillus cereus ATCC 10987]). C-terminal rhs-domain (Aa 1450-2070) ((AAC32486.1| RhsA [Streptomyces clavuligerus]; ZP_00251926.1| COG3209: Rhs family protein [Bacillus anthracis str. A1055]).; Function unclear; hypothetical protein 709446..716102 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174631 YP_001221368.1 CDS CMM_0628 NC_009480.1 716740 717177 R putative transcriptional regulator, AsnC family (CAB02066.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ASNC-FAMILY) [Mycobacterium tuberculosis H37Rv]; NP_625510.1| putative AsnC-family regulatory protein [Streptomyces coelicolor A3(2)]). related to leucine-responsive regulatory protein: MEDIATES A GLOBAL RESPONSE TO LEUCINE. EXOGENOUS LEUCINE AFFECTS THE EXPRESSION OF A NUMBER OF DIFFERENT OPERONS; LRP MEDIATES THIS EFFECT FOR AT LEAST SOME OF THESE OPERONS. FOR EXAMPLE IT IS REGULATOR OF THE BRANCHED-CHAIN AMINO ACID TRANSPORT GENES. pfam01037, AsnC_trans_reg, AsnC family. The AsnC family is a family of similar bacterial transcription regulatory proteins.; Specificity unclear; AsnC family transcriptional regulator complement(716740..717177) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173623 YP_001221369.1 CDS CMM_0629 NC_009480.1 717361 718203 D hypothetical protein 717361..718203 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173656 YP_001221370.1 CDS rocD NC_009480.1 718242 719486 D putative ornithine aminotransferase ( NP_824597.1| putative ornithine aminotransferase [Streptomyces avermitilis MA-4680]; ZP_00058716.1| COG4992: Ornithine/acetylornithine aminotransferase [Thermobifida fusca]). pfam00202, Aminotran_3, Aminotransferase class-III.; High confidence in function and specificity; putative ornithine aminotransferase 718242..719486 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173742 YP_001221371.1 CDS CMM_0631 NC_009480.1 719607 720104 D hypothetical protein 719607..720104 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173010 YP_001221372.1 CDS CMM_0632 NC_009480.1 720135 720782 D hypothetical protein 720135..720782 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173674 YP_001221373.1 CDS CMM_0633 NC_009480.1 720800 721792 R putative permease, DMT family (YP_062089.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_938965.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam00892,DUF6, Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function. InterPro: Integral membrane protein DUF6 2A78: Carboxylate/Amino Acid/Amine Tra; Specificity unclear; permease DMT family complement(720800..721792) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173764 YP_001221374.1 CDS CMM_0634 NC_009480.1 721857 722258 R hypothetical protein complement(721857..722258) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173698 YP_001221375.1 CDS CMM_0635 NC_009480.1 722346 723230 R putative NDP-sugar epimerase (ZP_00185910.1| hypothetical protein Rxyl332801 [Rubrobacter xylanophilus DSM 9941]; NP_103218.1| UDP-galactose 4-epimerase [Mesorhizobium loti MAFF303099]). pfam01370, Epimerase,NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Function unclear; putative NDP-sugar epimerase complement(722346..723230) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173822 YP_001221376.1 CDS CMM_0636 NC_009480.1 723227 723643 R hypothetical protein complement(723227..723643) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173773 YP_001221377.1 CDS CMM_0637 NC_009480.1 723640 724875 R putative benzoate transporter, BenE family (NP_386459.1| PUTATIVE MEMBRANE TRANSPORT PROTEIN [Sinorhizobium meliloti 1021]; ZP_00225740.1| COG3135: Uncharacterized protein involved in benzoate metabolism [Kineococcus radiotolerans SRS30216]). pfam03594, BenE,Benzoate membrane transport protein. InterPro: Benzoate membrane transport protein benE: benzoate membrane transport prot MFS transporter, subfamily 14; Specificity unclear; benzoate transport protein BenE family complement(723640..724875) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173846 YP_001221378.1 CDS CMM_0638 NC_009480.1 725136 726395 D putative membrane metalloendopeptidase, subfamily M23B (YP_062953.1| cell wall binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00098490.1| COG0739: Membrane proteins related to metalloendopeptidases [Desulfitobacterium hafniense]; NP_693412.1| hypothetical protein OB2491 [Oceanobacillus iheyensis HTE831]). pfam01551, Peptidase_M37, Peptidase family M23/M37. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M37 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated.; Function unclear; M23 family membrane bound metalloendopeptidase 725136..726395 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173797 YP_001221379.1 CDS CMM_0639 NC_009480.1 726453 727175 D conserved hypothetical protein (ZP_00137144.2| COG2755: Lysophospholipase L1 and related esterases [Pseudomonas aeruginosa UCBPP-PA14]; ZP_00220463.1| COG2755: Lysophospholipase L1 and related esterases [Burkholderia cepacia R1808]).; Family membership; hypothetical protein 726453..727175 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173900 YP_001221380.1 CDS CMM_0640 NC_009480.1 727339 727794 D conserved hypothetical prtoein (ZP_00192028.2| COG5637: Predicted integral membrane protein [Kineococcus radiotolerans SRS30216]; NP_821603.1| hypothetical protein SAV428 [Streptomyces avermitilis MA-4680]). surE: stationary-phase survival protein S; hypothetical protein 727339..727794 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173948 YP_001221381.1 CDS CMM_0641 NC_009480.1 727797 728033 D hypothetical protein 727797..728033 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173977 YP_001221382.1 CDS CMM_0642 NC_009480.1 728165 728962 D putative membrane protein (NP_824620.1| hypothetical protein SAV3443 [Streptomyces avermitilis MA-4680]; ZP_00228318.1| COG1714: Predicted membrane protein/domain [Kineococcus radiotolerans SRS30216]). pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).; hypothetical protein 728165..728962 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173963 YP_001221383.1 CDS CMM_0643 NC_009480.1 729154 730227 D putative NAD(P)H-dependent oxidoreductase (ZP_00227298.1| COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family [Kineococcus radiotolerans SRS30216]; NP_737709.1| putative NAD(P)H-dependent 2-cyclohexen-1-one reductase [Corynebacterium efficiens YS-314]). pfam00724, Oxidored_FMN, NADH:flavin oxidoreductase / NADH oxidase family.; Function unclear; putative oxidoreductase 729154..730227 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174004 YP_001221384.1 CDS CMM_0644 NC_009480.1 730274 731011 R putative two-component system, response regulator (ZP_00058730.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Thermobifida fusca]; NP_630354.1| putative two-component system response regulator [Streptomyces coelicolor A3(2)]). pfam00072, Response_reg, Response regulator receiver domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system, response regulator complement(730274..731011) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174026 YP_001221385.1 CDS CMM_0645 NC_009480.1 731008 732228 R putative two-component system sensor kinase (ZP_00226573.1| COG4585: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]; NP_827214.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; ZP_00058731.1| COG4585: Signal transduction histidine kinase [Thermobifida fusca]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-,and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase complement(731008..732228) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174089 YP_001221386.1 CDS CMM_0646 NC_009480.1 732294 732650 R putative membrane protein (NP_939424.1| Putative integral membrane protein [Corynebacterium diphtheriae]; NP_827987.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; Hypothetical protein; hypothetical protein complement(732294..732650) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174039 YP_001221387.1 CDS CMM_0647 NC_009480.1 732755 733354 R putative transcriptional regulator, TetR family (NP_959008.1| hypothetical protein MAP0074 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_629094.1| putative regulatory protein [Streptomyces coelicolor A3(2)]). pfam00440, TetR_N, Bacterial regulatory proteins,tetR family.; Specificity unclear; TetR family transcriptional regulator complement(732755..733354) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174105 YP_001221388.1 CDS CMM_0648 NC_009480.1 733415 734998 D putative efflux MFS permease (NP_825134.1| putative transport integral membrane protein [Streptomyces avermitilis MA-4680]; ZP_00189667.3| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative efflux MFS permease 733415..734998 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174070 YP_001221389.1 CDS CMM_0649 NC_009480.1 735725 736021 D Hypothetical protein; hypothetical protein 735725..736021 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174172 YP_001221390.1 CDS CMM_0650 NC_009480.1 736095 737114 R putative monooxygenase (NP_822331.1| putative monooxygenase [Streptomyces avermitilis MA-4680]; ZP_00227515.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]). pfam00296, Bac_luciferase,Luciferase-like monooxygenase.; Function unclear; putative monooxygenase complement(736095..737114) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174148 YP_001221391.1 CDS CMM_0651 NC_009480.1 737194 738264 R putative monooxygenase (NP_822331.1| putative monooxygenase [Streptomyces avermitilis MA-4680]; ZP_00227515.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]). pfam00296, Bac_luciferase,Luciferase-like monooxygenase. InterPro: Bacterial luciferase; Function unclear; putative monooxygenase complement(737194..738264) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174247 YP_001221392.1 CDS qorA NC_009480.1 738309 739274 R putative Zn-dependant quinone oxidoreductase (ZP_00227353.1| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_215970.1| qor [Mycobacterium tuberculosis H37Rv]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; putative Zn-dependent quinone oxidoreductase complement(738309..739274) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174214 YP_001221393.1 CDS cysK NC_009480.1 739395 740333 D Cysteine synthase chloroplast precursor (O-acetylserine sulfhydrylase) (O-acetylserine (Thiol)-lyase) (NP_739056.1| putative cysteine synthase [Corynebacterium efficiens YS-314]; NP_903231.1| cysteine synthase [Chromobacterium violaceum ATCC 12472]). pfam00291, PALP,Pyridoxal-phosphate dependent enzyme. InterPro: Pyridoxal-5-phosphate-dependent enzymes beta family; High confidence in function and specificity; hypothetical protein 739395..740333 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175534 YP_001221394.1 CDS cysE NC_009480.1 740336 740920 D putative serine O-acetyltransferase (YP_061730.1| serine O-acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_940228.1| serine acetyltransferase [Corynebacterium diphtheriae NCTC 13129]).; High confidence in function and specificity; putative serine O-acetyltransferase 740336..740920 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175124 YP_001221395.1 CDS CMM_0655 NC_009480.1 740920 741579 D putative RNA methyltransferase (RNA methylase) (YP_063092.1| tRNA/rRNA methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293932.1| COG0566: rRNA methylases [Thermobifida fusca]). pfam00588,SpoU_methylase, SpoU rRNA Methylase family. This family of proteins probably use S-AdoMet. rRNA_methyl_2: RNA methyltransferase T.; Specificity unclear; putative RNA methyltransferase 740920..741579 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174641 YP_001221396.1 CDS CMM_0656 NC_009480.1 741611 742171 D conserved hypothetical protein (NP_631271.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00229139.1| COG2320: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]). pfam04229,UPF0157, Uncharacterised protein family (UPF0157). Also known as GrpB.; Function unclear; hypothetical protein 741611..742171 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174272 YP_001221397.1 CDS CMM_0657 NC_009480.1 742168 742569 R hypothetical protein (NP_626702.1| hypothetical protein SCC24.30c [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(742168..742569) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174299 YP_001221398.1 CDS CMM_0658 NC_009480.1 742620 743141 D putative endoribonuclease (NP_733554.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_771770.1| bll5130 [Bradyrhizobium japonicum USDA 110]). pfam01042, Ribonuc_L-PSP, Endoribonuclease L-PSP. Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis.; Function unclear; putative endoribonuclease L-PSP 742620..743141 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174417 YP_001221399.1 CDS addB NC_009480.1 743160 744161 R putative adenosine deaminase (Adenosine aminohydrolase 3) (NP_826754.1| putative adenosine deaminase [Streptomyces avermitilis MA-4680]; YP_062278.1| adenosine deaminase protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00962, A_deaminase,Adenosine/AMP deaminase. InterPro: Adenosine and AMP deaminase; High confidence in function and specificity; putative adenosine deaminase complement(743160..744161) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174348 YP_001221400.1 CDS CMM_0660 NC_009480.1 744239 744547 D hypothetical protein 744239..744547 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174055 YP_001221401.1 CDS CMM_0661 NC_009480.1 745338 748628 D conserved hypothetical protein (NP_627580.1| putative large ATP-binding protein [Streptomyces coelicolor A3(2)]; ZP_00162995.2| COG1413: FOG: HEAT repeat [Anabaena variabilis ATCC 29413]). COG5635,Predicted NTPase (NACHT family) [Signal transduction mechanisms]. pfam05729, NACHT, NACHT domain. This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.; Function unclear; hypothetical protein 745338..748628 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173243 YP_001221402.1 CDS adhA NC_009480.1 748784 749830 R NADP-dependent alcohol dehydrogenase (ZP_00226305.1| COG1064: Zn-dependent alcohol dehydrogenases [Kineococcus radiotolerans SRS30216]; CAC35017.1| alcohol dehydrogenase, class C [Mycobacterium smegmatis]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; NADP-dependent alcohol dehydrogenase complement(748784..749830) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174398 YP_001221403.1 CDS CMM_0663 NC_009480.1 749984 751369 D putative carboxylesterase, type B (P37967|PNBA_BACSU Para-nitrobenzyl esterase (PNB carboxy-esterase) (PNBCE); NP_628470.1| putative carboxylesterase [Streptomyces coelicolor A3(2)]). pfam00135, COesterase,Carboxylesterase.; Specificity unclear; putative carboxylesterase, type B 749984..751369 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175247 YP_001221404.1 CDS SoxR NC_009480.1 751420 751908 R putative transcriptional regulator, MerR family (BAD30046.1| hypothetical protein [Rhodococcus opacus]; ZP_00084416.1| COG0789: Predicted transcriptional regulators [Pseudomonas fluorescens PfO-1]; NP_890689.1| putative MerR-family transcriptional regulator [Bordetella bronchiseptica RB50]). pfam00376, MerR, MerR family regulatory protein., binding; Specificity unclear; hypothetical protein complement(751420..751908) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174562 YP_001221405.1 CDS fdxA NC_009480.1 752015 752341 D ferredoxin (YP_062518.1| ferredoxin [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787703.1| ferredoxin [Tropheryma whipplei str. Twist]; NP_629284.1| ferredoxin [Streptomyces coelicolor A3(2)]). pfam00037, Fer4, 4Fe-4S binding domain. Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases.; High confidence in function and specificity; hypothetical protein 752015..752341 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174689 YP_001221406.1 CDS CMM_0666 NC_009480.1 752338 752832 D putative flavin-dependant reductase (NP_822657.1| putative flavin-dependent reductase [Streptomyces avermitilis MA-4680]; AAC38226.1| NADH-dependent FMN oxydoreductase [Rhodococcus erythropolis]). pfam01613,Flavin_Reduct, Flavin reductase like domain. This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components.; Specificity unclear; putative flavin-dependent reductase 752338..752832 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172953 YP_001221407.1 CDS CMM_0667 NC_009480.1 752869 754794 R putative secreted phosphoesterase (NP_631671.1| putative secreted protein [Streptomyces coelicolor A3(2)]; ZP_00199472.2| COG1409: Predicted phosphohydrolases [Kineococcus radiotolerans SRS30216]; AAO54034.1| Ser/Thr protein phosphatase family protein [Pseudomonas syringae pv. tomato str. DC3000]). pfam00149,Metallophos, Calcineurin-like phosphoesterase. This family includes a diverse range of phosphoesterases.; Function unclear; putative secreted phosphoesterase complement(752869..754794) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174477 YP_001221408.1 CDS CMM_0668 NC_009480.1 755391 756011 D conserved hypothetical protein, putative phosphohydrolase (AAN85489.1| putative cyanamide hydratase [Streptomyces atroolivaceus]; ZP_00170298.2| COG1418: Predicted HD superfamily hydrolase [Ralstonia eutropha JMP134]). pfam01966, HD, HD domain. HD domains are metal dependent phosphohydrolases.; Function unclear; putative phosphohydrolase 755391..756011 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174612 YP_001221409.1 CDS CMM_0669 NC_009480.1 756008 756292 D hypothetical protein 756008..756292 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174533 YP_001221410.1 CDS CMM_0670 NC_009480.1 756289 756963 R hypothetical protein complement(756289..756963) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174620 YP_001221411.1 CDS CMM_0671 NC_009480.1 757050 759155 R conserved membrane protein (YP_063090.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827281.1| putative membrane protein [Streptomyces avermitilis MA-4680]; NP_939709.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]). weak similarities to: pfam01061, ABC2_membrane, ABC-2 type transporter; and pfam00015, MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain. This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.; Function unclear; hypothetical protein complement(757050..759155) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174654 YP_001221412.1 CDS CMM_0672 NC_009480.1 759152 759820 R hypothetical protein with ATPase domain (CAF21648.1| conserved hypothetical protein [Corynebacterium glutamicum ATCC 13032]; ZP_00225487.1| COG1131: ABC-type multidrug transport system, ATPase component [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein complement(759152..759820) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174821 YP_001221413.1 CDS CMM_0673 NC_009480.1 759817 760500 R putative transcriptional regulator, TetR-family (YP_063089.1| transcriptional regulator, TetR family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_823990.1| hypothetical protein SAV2814 [Streptomyces avermitilis MA-4680]; NP_768856.1| transcriptional regulatory protein [Bradyrhizobium japonicum]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator complement(759817..760500) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174701 YP_001221414.1 CDS CMM_0674 NC_009480.1 760594 761907 R putative transcriptional regulator, AraC family (NP_519953.1| PROBABLE TRANSCRIPTION REGULATOR PROTEIN [Ralstonia solanacearum GMI1000]; NP_962164.1| hypothetical protein MAP3230c [Mycobacterium avium subsp. paratuberculosis str. k10]). smart00342, HTH_ARAC,helix_turn_helix, arabinose operon control protein. COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Specificity unclear; AraC family transcriptional regulator complement(760594..761907) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174941 YP_001221415.1 CDS CMM_0675 NC_009480.1 762248 762451 D Hypothetical protein; hypothetical protein 762248..762451 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174759 YP_001221416.1 CDS sbcC NC_009480.1 762473 765496 R putative dsDNA exonuclease subunit (NP_828232.1| putative exonuclease [Streptomyces avermitilis MA-4680]; AE1643 ATP-dependent dsDNA exonuclease SbcC homolog sbcC [imported] -Listeria innocua (strain Clip11262)). SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3->5 double strand exonuclease that can open hairpins. It also has a 5 single-strand endonuclease activity (By similarity).; High confidence in function and specificity; putative exonuclease complement(762473..765496) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175043 YP_001221417.1 CDS sbcD NC_009480.1 765496 766662 R putative dsDNA exonuclease subunit (NP_625587.1| putative exonuclease [Streptomyces coelicolor A3(2)]; NP_800533.1| putative exonuclease SbcD [Vibrio parahaemolyticus RIMD 2210633]). SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3->5 double strand exonuclease that can open hairpins. It also has a 5 single-strand endonuclease activity. InterPro: DNA repair exonuclease sbcd: exonuclease SbcD; High confidence in function and specificity; putative dsDNA exonuclease subunit complement(765496..766662) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175716 YP_001221418.1 CDS pknC NC_009480.1 766983 769637 D putative serine/threonine-protein kinase (NP_630756.1| putative serine/threonine protein kinase [Streptomyces coelicolor A3(2)]; NP_345802.1| conserved hypothetical protein [Streptococcus pneumoniae TIGR4]). pfam00069, Pkinase, Protein kinase domain. smart00220,S_TKc, Serine/Threonine protein kinases, catalytic domain; Phosphotransferases. Serine or threonine-specific kinase subfamily.; Function unclear; putative serine/threonine-protein kinase 766983..769637 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175910 YP_001221419.1 CDS CMM_0679 NC_009480.1 769707 770345 D putative acetyltransferase (NP_979782.1| acetyltransferase, GNAT family [Bacillus cereus ATCC 10987]; ZP_00200227.1| COG1670: Acetyltransferases,including N-acetylases of ribosomal proteins [Rubrobacter xylanophilus DSM 9941]).; Function unclear; hypothetical protein 769707..770345 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173559 YP_001221420.1 CDS CMM_0680 NC_009480.1 770342 773032 D putative acyl-CoA ligase/aldehyde dehydrogenase contains two domains: N-terminal: CoA ligase (COG0318,CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II ; pfam00501, AMP-binding, AMP-binding enzyme; ZP_00170177.2| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Ralstonia eutropha JMP134]; ZP_00029907.1| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Burkholderia fungorum]). C-terminal: Dehydrogenase (COG1012, PutA, NAD-dependent aldehyde dehydrogenases; CAC38029.1| aldehyde dehydrogenase [Alcanivorax borkumensis]; ZP_00080991.1| COG1012: NAD-dependent aldehyde dehydrogenases [Geobacter metallireducens]).; Specificity unclear; putative acyl-CoA ligase/aldehyde dehydrogenase 770342..773032 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174973 YP_001221421.1 CDS fabB NC_009480.1 773029 774276 D 3-oxoacyl-[acyl-carrier-protein] synthase (Beta-ketoacyl-ACP synthase) (ZP_00331147.1| COG0304: 3-oxoacyl-(acyl-carrier-protein) synthase [Moorella thermoacetica ATCC 39073]; ZP_00289321.1| COG0304: 3-oxoacyl-(acyl-carrier-protein) synthase [Magnetococcus sp. MC-1])., ,CATALYZES THE CONDENSATION REACTION OF FATTY ACID SYNTHESIS BY THE ADDITION TO AN ACYL ACCEPTOR OF TWO CARBONS FROM MALONYL-ACP. HAS A PREFERENCE FOR SHORT CHAIN ACID SUBSTRATES., , pfam00109, ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain. pfam02801, Ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain. fabH: 3-oxoacyl-(acyl-carrier-protein); High confidence in function and specificity; 3-oxoacyl-ACP synthase 773029..774276 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175065 YP_001221422.1 CDS ilvG NC_009480.1 774273 775922 D putative acetolactate synthase large subunit (Acetohydroxy-acid synthase large subunit) (YP_052316.1| acetolactate synthase isozyme II large subunit [Erwinia carotovora subsp. atroseptica SCRI1043]; NP_931847.1| acetolactate synthase isozyme II large subunit (AHAS-II) (acetohydroxy-acid synthase II large subunit) (ALS-II)[Photorhabdus luminescens subsp. laumondii TTO1]. pfam02776, TPP_enzyme_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. pfam00205, TPP_enzyme_M,Thiamine pyrophosphate enzyme, central domain. pfam02775,TPP_enzyme_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.; High confidence in function and specificity; putative acetolactate synthase 774273..775922 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175974 YP_001221423.1 CDS coaBC NC_009480.1 775919 776554 D putative pantothenate metabolism flavoprotein (|AAD21550.1| pantothenate metabolism flavoprotein [Zymomonas mobilis]; ZP_00318608.1| COG0452: Phosphopantothenoylcysteine synthetase/decarboxylase [Oenococcus oeni PSU-1]). pfam02441, Flavoprotein,Flavoprotein. This family contains diverse flavoprotein enzymes.; Function unclear; putative pantothenate metabolism flavoprotein 775919..776554 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175064 YP_001221424.1 CDS CMM_0684 NC_009480.1 776547 777245 D putative antimicrobial peptide ABC transporter, ATP-binding protein (NP_815381.1| ABC transporter, ATP-binding protein [Enterococcus faecalis V583]; ZP_00283781.1| COG1136: ABC-type antimicrobial peptide transport system,ATPase component [Burkholderia fungorum LB400]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; peptide ABC transporter ATP-binding protein 776547..777245 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173752 YP_001221425.1 CDS CMM_0685 NC_009480.1 777242 778471 D putative antimicrobial peptide ABC transporter,permease component (NP_815380.1| permease protein,putative [Enterococcus faecalis V583]; ZP_00227187.1| COG0577: ABC-type antimicrobial peptide transport system,permease component [Kineococcus radiotolerans SRS30216]).; Specificity unclear; peptide ABC transporter permease 777242..778471 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174986 YP_001221426.1 CDS CMM_0686 NC_009480.1 778696 779385 D hypothetical membrane protein (NP_960625.1| hypothetical protein MAP1691c [Mycobacterium avium subsp. paratuberculosis str. k10]; CAF19632.1| putative membrane protein [Corynebacterium glutamicum ATCC 13032]). only very weak similarity to: pfam02683, DsbD, Cytochrome C biogenesis protein transmembrane region.; hypothetical protein 778696..779385 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175097 YP_001221427.1 CDS CMM_0687 NC_009480.1 779420 780259 R putative short-chain alcohol oxidoreductase (NP_103147.1| oxidoreductase of short-chain [Mesorhizobium loti MAFF303099]; ZP_00227341.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; short chain dehydrogenase complement(779420..780259) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175144 YP_001221428.1 CDS CMM_0688 NC_009480.1 780416 780892 D conserved hypothetical protein (NP_825702.1| hypothetical protein SAV4525 [Streptomyces avermitilis MA-4680]; NP_962798.1| hypothetical protein MAP3864 [Mycobacterium avium subsp. paratuberculosis str. k10]).; hypothetical protein 780416..780892 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175193 YP_001221429.1 CDS purA NC_009480.1 780975 782264 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 780975..782264 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175178 YP_001221430.1 CDS CMM_0690 NC_009480.1 782357 782485 D hypothetical protein 782357..782485 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174853 YP_001221431.1 CDS CMM_0691 NC_009480.1 782498 782950 R putative transcriptional regulator, MarR family (NP_631735.1| putative marR-family transcriptional regulator [Streptomyces coelicolor A3(2)]; CAA98363.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator complement(782498..782950) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175283 YP_001221432.1 CDS CMM_0692 NC_009480.1 783012 783380 D conserved hypothetical protein (NP_631734.1| hypothetical protein [Streptomyces coelicolor A3(2)]; NP_532221.1| glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein [Agrobacterium tumefaciens str. C58]). pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; hypothetical protein 783012..783380 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175351 YP_001221433.1 CDS CMM_0693 NC_009480.1 783456 784205 D hypothetical protein 783456..784205 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174910 YP_001221434.1 CDS CMM_0694 NC_009480.1 784209 784745 R putative ATP/GTP binding protein (NP_625858.1| ATP/GTP binding protein [Streptomyces coelicolor A3(2)]; NP_814788.1| tunicamycin resistance protein, putative [Enterococcus faecalis V583]).; Conserved hypothetical protein; hypothetical protein complement(784209..784745) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175386 YP_001221435.1 CDS CMM_0695 NC_009480.1 784899 785327 D conserved hypothetical protein (NP_738977.1| hypothetical protein [Corynebacterium efficiens YS-314]; NP_903029.1| conserved hypothetical protein [Chromobacterium violaceum ATCC 12472]). pfam04940, BLUF,Sensors of blue-light using FAD. The BLUF domain has been shown to bind FAD in the AppA protein.; hypothetical protein 784899..785327 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175027 YP_001221436.1 CDS CMM_0696 NC_009480.1 785365 786303 R putative hydrolase (NP_824275.1| putative hydrolase [Streptomyces avermitilis MA-4680]; ZP_00057512.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Thermobifida fusca]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase complement(785365..786303) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174788 YP_001221437.1 CDS CMM_0697 NC_009480.1 786349 786603 R putative transcriptional regulator, Cro/CI family (NP_656871.1| HTH_XRE, Helix-turn-helix XRE-family like proteins [Bacillus anthracis A2012]; ZP_00035555.2| hypothetical protein Efae020552 [Enterococcus faecium]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. InterPro: Helix-turn-helix motif; Specificity unclear; Cro/CI family transcriptional regulator complement(786349..786603) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175339 YP_001221438.1 CDS CMM_0698 NC_009480.1 786623 787300 R hypothetical protein complement(786623..787300) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173785 YP_001221439.1 CDS CMM_0699 NC_009480.1 787367 788857 R two component system, sensor kinase (NP_960156.1| hypothetical protein MAP1222 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_951511.1| sensor histidine kinase [Geobacter sulfurreducens PCA]; NP_739103.1| putative sensor kinase [Corynebacterium efficiens YS-314]). pfam00672, HAMP, HAMP domain. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Function unclear; two component system, sensor kinase complement(787367..788857) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175826 YP_001221440.1 CDS CMM_0700 NC_009480.1 788854 789522 R putative two-component system response regulator (NP_960155.1| hypothetical protein MAP1221 [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00225501.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Kineococcus radiotolerans SRS30216]). pfam00072,Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. pfam00486, Trans_reg_C,Transcriptional regulatory protein, C terminal. InterPro: Response regulator receiver domain.; Function unclear; putative two-component system response regulator complement(788854..789522) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174623 YP_001221441.1 CDS CMM_0701 NC_009480.1 789670 790368 D hypothetical protein 789670..790368 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175953 YP_001221442.1 CDS CMM_0702 NC_009480.1 790440 791081 D putative acetyltransferase (AAC03422.1| unknown [Myxococcus xanthus]; NP_711398.1| probable Acetyltransferase, GNAT family protein [Leptospira interrogans serovar lai str. 56601]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 790440..791081 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175784 YP_001221443.1 CDS CMM_0703 NC_009480.1 791116 791481 R hypothetical protein complement(791116..791481) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175226 YP_001221444.1 CDS CMM_0704 NC_009480.1 791849 792331 R hypothetical protein complement(791849..792331) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174814 YP_001221445.1 CDS CMM_0705 NC_009480.1 792796 793188 D conserved hypothetical protein (NP_243026.1| BH2160~unknown conserved protein [Bacillus halodurans]; NP_691431.1| hypothetical protein OB0510 [Oceanobacillus iheyensis HTE831]). pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; hypothetical protein 792796..793188 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175960 YP_001221446.1 CDS pbpB NC_009480.1 793298 795367 D putative beta lactamase/penicillin-binding protein (NP_832928.1| Penicillin-binding protein [Bacillus cereus ATCC 14579]; NP_335363.1| penicillin-binding protein 4 [Mycobacterium tuberculosis CDC1551]). pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and pfam00768 D-alanyl-D-alanine carboxypeptidase.; Function unclear; putative beta lactamase/penicillin-binding protein 793298..795367 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175840 YP_001221447.1 CDS CMM_0707 NC_009480.1 795421 796800 D putative two-component system, sensor kinase (NP_627597.1| putative two component sensor kinase [Streptomyces coelicolor A3(2)]; ZP_00294209.1| COG4585: Signal transduction histidine kinase [Thermobifida fusca]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase- DNA gyrase B- phytochrome-like ATPase.; Specificity unclear; putative two-component system, sensor kinase 795421..796800 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175491 YP_001221448.1 CDS CMM_0708 NC_009480.1 796797 797477 D putative two-component system response regulator (ZP_00227053.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]; NP_625364.1| putative two component system response regulator [Streptomyces coelicolor A3(2)]). pfam00072, Response_reg,Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system response regulator 796797..797477 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175931 YP_001221449.1 CDS CMM_0709 NC_009480.1 797660 798079 D stress-induced protein, putative organic hydroperoxide resistance protein (CNP_599276.2| stress-induced protein [Corynebacterium glutamicum ATCC 13032]; YP_055293.1| stress-induced protein [Propionibacterium acnes KPA171202]). pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.; Function unclear; stress-induced protein organic hydroperoxide resistance protein 797660..798079 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175260 YP_001221450.1 CDS tyrA NC_009480.1 798162 798545 D putative chorismate mutase (YP_063084.1| chorismate mutase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626280.1| putative chorismate mutase [Streptomyces coelicolor A3(2)]). pfam01817, Chorismate_mut, Chorismate mutase. InterPro: Chorismate mutase; High confidence in function and specificity; hypothetical protein 798162..798545 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175132 YP_001221451.1 CDS CMM_0711 NC_009480.1 798577 799560 R conserved hypothetical protein (ZP_00189995.2| COG0189: Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Kineococcus radiotolerans SRS30216]; NP_860745.1| conserved hypothetical protein [Helicobacter hepaticus ATCC 51449]). rimK_fam: S6 modification enzyme RimK fa; hypothetical protein complement(798577..799560) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173898 YP_001221452.1 CDS CMM_0712 NC_009480.1 799650 800480 R conserved hypothetical protein (NP_822654.1| hypothetical protein [Streptomyces avermitilis MA-4680]; NP_691380.1| hypothetical protein OB0459 [Oceanobacillus iheyensis HTE831]). pfam03372, Exo_endo_phos,Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling.; Family membership; hypothetical protein complement(799650..800480) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175321 YP_001221453.1 CDS CMM_0713 NC_009480.1 800539 801126 R conserved hypothetical protein (CAF18943.1| putative secreted protein [Corynebacterium glutamicum ATCC 13032]; NP_662037.1| conserved hypothetical protein [Chlorobium tepidum TLS]).; Function unclear; hypothetical protein complement(800539..801126) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175783 YP_001221454.1 CDS CMM_0714 NC_009480.1 801284 803158 R hypothetical protein (ZP_00120551.1| hypothetical protein [Bifidobacterium longum DJO10A]; ZP_00199275.1| hypothetical protein Krad06001109 [Kineococcus radiotolerans SRS30216]).; hypothetical protein complement(801284..803158) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175961 YP_001221455.1 CDS wzy2 NC_009480.1 803155 804867 R conserved membrane protein, putative polysaccharide polymerase (only weak similarities: AAC45844.1| putative O-antigen polymerase [Escherichia coli]) may be involved in EPS biosynthesis; Hypothetical protein; putative polysaccharide polymerase complement(803155..804867) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175364 YP_001221456.1 CDS wcnG NC_009480.1 804846 805895 R putative pyruvyl-transferase (NP_830681.1| putative pyruvyl- transferase [Bacillus cereus ATCC 14579]; CAB92958.1| putative pyruvyl-transferase [Thermoanaerobacter thermohydrosulfuricus]). pfam04230,PS_pyruv_trans, Polysaccharide pyruvyl transferase. Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. weak similarity to: COG2327, WcaK,Uncharacterized conserved protein [Function unknown].; Conserved hypothetical protein; putative pyruvyl-transferase complement(804846..805895) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174066 YP_001221457.1 CDS wzx2 NC_009480.1 805892 807082 R putative membrane protein may be involved in the biosynthesis of EPS. weak similarity to: COG2244, RfbX,Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only], and pfam01943, Polysacc_synt, Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide.; Hypothetical protein; hypothetical protein complement(805892..807082) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173200 YP_001221458.1 CDS wcnE NC_009480.1 807079 808125 R putative mannosyltransferase (ZP_00033687.1| COG0438: Glycosyltransferase [Burkholderia fungorum]; AAF04384.1| WbdB; mannosyl transferase B [Klebsiella pneumoniae]). pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars; Specificity unclear; putative mannosyltransferase complement(807079..808125) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173994 YP_001221459.1 CDS wcnD NC_009480.1 808125 809255 R putative glycosyltransferase (ZP_00226742.1| COG0438: Glycosyltransferase [Kineococcus radiotolerans SRS30216]; NP_924472.1| probable glycosyltransferase [Gloeobacter violaceus]; BAA94399.1| mannosyl transferase [Actinobacillus actinomycetemcomitans]). pfam00534,Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP,ADP, GDP or CMP linked sugars.; Specificity unclear; putative glycosyltransferase complement(808125..809255) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173181 YP_001221460.1 CDS wcnC NC_009480.1 809255 810730 R putative undecaprenyl-phosphate galactosephosphotransferase (ZP_00228118.1| COG2148: Sugar transferases involved in lipopolysaccharide synthesis [Kineococcus radiotolerans SRS30216]; NP_624703.1| putative glycosyl transferase [Streptomyces coelicolor A3(2)]; NP_695455.1| undecaprenyl-phosphate sugar phosphotransferase [Bifidobacterium longum NCC2705]). pfam02397, Bac_transf, Bacterial sugar transferase. InterPro: Bacterial sugar transferase.; High confidence in function and specificity; putative undecaprenyl-phosphate sugar phosphotransferase complement(809255..810730) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173111 YP_001221461.1 CDS wzb NC_009480.1 810821 811540 R putative protein-tyrosine-phosphatase (NP_599596.1| protein-tyrosine-phosphatase [Corynebacterium glutamicum ATCC 13032]; NP_695454.1| hypothetical protein with possible low molecular weight protein-tyrosine-phosphatase domain [Bifidobacterium longum NCC2705]). pfam01451,LMWPc, Low molecular weight phosphotyrosine protein phosphatase.; Specificity unclear; hypothetical protein complement(810821..811540) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173154 YP_001221462.1 CDS wzc NC_009480.1 811550 812962 R putative capsular polysaccharide biosynthesis protein, putative protein tyrosine kinase (CAF19058.1| cell surface polysaccharide biosynthesis / Chain length determinant protein [Corynebacterium glutamicum ATCC 13032]; NP_696399.1| possible Etk-like tyrosine kinase involved in Eps biosynthesis [Bifidobacterium longum NCC2705]). two domains. N-terminal: COG3944, Capsular polysaccharide biosynthesis protein; pfam02706, Wzz, Chain length determinant protein. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases. C-terminal: COG0489, Mrp, ATPases involved in chromosome partitioning; Function unclear; putative protein tyrosine kinase complement(811550..812962) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173821 YP_001221463.1 CDS wcnB NC_009480.1 813177 815450 D putative acyltransferase (ZP_00057849.1| COG1835: Predicted acyltransferases [Thermobifida fusca]; CAF19073.1| PROBABLE LIPOPOLYSACCHARIDE MODIFICATION ACYLTRANS [Corynebacterium glutamicum ATCC 13032]). potentially involved in the biosynthesis of (Exo)polysaccharides. pfam01757, Acyl_transf_3,Acyltransferase family. This family includes a range of acyltransferase enzymes.; Family membership; putative acyltransferase 813177..815450 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173802 YP_001221464.1 CDS wcnA NC_009480.1 815640 816677 R putative acyltransferase (NP_626735.1| putative membrane protein [Streptomyces coelicolor A3(2)]; NP_102483.1| probable lipopolysaccharide modification acyltransferase [Mesorhizobium loti MAFF303099]). pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes.; Specificity unclear; putative membrane-bound acyltransferase complement(815640..816677) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173029 YP_001221465.1 CDS CMM_0725 NC_009480.1 816769 817479 R putative esterase (only weak similarities,ZP_00071593.1| COG2755: Lysophospholipase L1 and related esterases [Trichodesmium erythraeum IMS101]; NP_809482.1| conserved hypothetical protein [Bacteroides thetaiotaomicron VPI-5482]). pfam00657, Lipase_GDSL, GDSL-like Lipase/Acylhydrolase.; Family membership; putative esterase complement(816769..817479) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173033 YP_001221466.1 CDS CMM_0726 NC_009480.1 817680 818729 R conserved hypothetical protein (NP_822654.1| hypothetical protein [Streptomyces avermitilis MA-4680]; NP_737707.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam03372,Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling.; Function unclear; hypothetical protein complement(817680..818729) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173780 YP_001221467.1 CDS CMM_0727 NC_009480.1 818980 819783 R putative dienelactone hydrolase (NP_967924.1| dienelactone hydrolase family protein [Bdellovibrio bacteriovorus HD100]; NP_866914.1| probable dienelactone hydrolase [Pirellula sp. 1]). pfam01738, DLH, Dienelactone hydrolase family. InterPro: Dienelactone hydrolase.; Family membership; putative hydrolase complement(818980..819783) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175852 YP_001221468.1 CDS purL NC_009480.1 819780 822140 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II complement(819780..822140) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175789 YP_001221469.1 CDS purQ NC_009480.1 822137 822832 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I complement(822137..822832) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174917 YP_001221470.1 CDS purS NC_009480.1 822832 823224 R putative phosphoribosylformylglycinamidine (FGAM) synthase component (ZP_00197960.1| COG1828: Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component [Kineococcus radiotolerans SRS30216]; ZP_00292269.1| COG1828: Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component [Thermobifida fusca]). pfam02700, PurC, Phosphoribosylformylglycinamidine (FGAM) synthase. This family forms a component of the de novo purine biosynthesis pathway.; High confidence in function and specificity; putative phosphoribosylformylglycinamidine (FGAM) synthase complement(822832..823224) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174977 YP_001221471.1 CDS CMM_0731 NC_009480.1 823345 824028 R conserved hypothetical protein, putative isomerase (ZP_00227845.1| COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Kineococcus radiotolerans SRS30216]; AAP42849.1| NanT2 [Streptomyces nanchangensis]; NP_889535.1| hypothetical protein BB2999 [Bordetella bronchiseptica RB50]).; Function unclear; hypothetical protein complement(823345..824028) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175358 YP_001221472.1 CDS CMM_0732 NC_009480.1 824193 825590 D putative MFS permease (ZP_00227844.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; AAP42848.1| NanT1 [Streptomyces nanchangensis]). pfam00083, Sugar_tr, Sugar (and other) transporter. TIGRFAM (TIGR00883): metabolite:proton symporter family protein; Specificity unclear; putative MFS permease 824193..825590 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175929 YP_001221473.1 CDS CMM_0733 NC_009480.1 825663 826337 R putative transcriptional regulator, GntR-family (ZP_00227843.1| COG1802: Transcriptional regulators [Kineococcus radiotolerans SRS30216]; NP_627999.1| putative gntR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00392, GntR,Bacterial regulatory proteins, gntR family.; Specificity unclear; GntR family transcriptional regulator complement(825663..826337) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175448 YP_001221474.1 CDS CMM_0734 NC_009480.1 826366 827205 D putative amidohydrolase (NP_302587.1| putative hydrolase [Mycobacterium leprae]; ZP_00227842.1| COG0388: Predicted amidohydrolase [Kineococcus radiotolerans SRS30216]). pfam00795, CN_hydrolase, Carbon-nitrogen hydrolase. This family contains hydrolases that break carbon-nitrogen bonds.; Function unclear; putative amidohydrolase 826366..827205 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175004 YP_001221475.1 CDS CMM_0735 NC_009480.1 827277 828266 R putative oxidoreductase (NP_960686.1| hypothetical protein MAP1752c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00107451.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Nostoc punctiforme]). pfam00248,Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative oxidoreductase complement(827277..828266) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175672 YP_001221476.1 CDS furA NC_009480.1 828392 828877 D transcriptional regulator, Fur family (Ferric uptake regulator) (O07724|FUR_MYCTU Ferric uptake regulation protein (Ferric uptake regulator); YP_061416.1| ferric uptake regulator, Fur family [Leifsonia xyli subsp. xyli str. CTCB07]) . may act as a global negative controlling element employing Fe(2+) as a cofactor to bind the operator of the repressed genes (By similarity). pfam01475, FUR, Ferric uptake regulator family. This family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes. This family is also known as the FUR family.; Specificity unclear; FUR family transcriptional regulator 828392..828877 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174930 YP_001221477.1 CDS katA NC_009480.1 828956 830485 D catalase (YP_061415.1| catalase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00294401.1| COG0753: Catalase [Thermobifida fusca]). pfam00199, Catalase,Catalase., , InterPro: Catalase; High confidence in function and specificity; hypothetical protein 828956..830485 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174442 YP_001221478.1 CDS CMM_0738 NC_009480.1 830624 832954 R hypothetical protein (NP_736862.1| hypothetical protein [Corynebacterium efficiens YS-314]; NP_233017.1| SecA-related protein [Vibrio cholerae O1 biovar eltor str. N16961]); hypothetical protein complement(830624..832954) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175644 YP_001221479.1 CDS CMM_0739 NC_009480.1 833418 833921 R putative acetyltransferase (ZP_00199016.1| hypothetical protein Krad022685 [Kineococcus radiotolerans SRS30216]; NP_825281.1| putative acetyltransferase [Streptomyces avermitilis MA-4680]). InterPro: GCN5-related N-acetyltransferase pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Family membership; putative acetyltransferase complement(833418..833921) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174740 YP_001221480.1 CDS CMM_0740 NC_009480.1 833936 834535 R putative acyltransferase (CAE30321.1| acyltransferase [Mesorhizobium septentrionale]; CAC82838.1| NodA protein [Sinorhizobium sp. ORS1044]).; Hypothetical protein; putative acyltransferase complement(833936..834535) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173915 YP_001221481.1 CDS CMM_0741 NC_009480.1 834599 835756 D conserved membrane protein (CAA17327.1| PROBABLE CONSERVED TRANSMEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_940438.1| Putative integral membrane protein [Corynebacterium diphtheriae]). ,InterPro: Domain of unknown function DUF20 , pfam01594,UPF0118, Domain of unknown function DUF20. This transmembrane region is found in putative permeases and predicted transmembrane proteins it has no known function. It is not clear what source suggested that these proteins may be permeases and this information should be treated with caution.; Function unclear; hypothetical protein 834599..835756 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175701 YP_001221482.1 CDS CMM_0742 NC_009480.1 835753 836553 D putative membrane protein (NP_738715.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00051056.1| hypothetical protein Magn025090 [Magnetospirillum magnetotacticum]). pfam06724, DUF1206,Domain of Unknown Function (DUF1206). This region consists of two a pair of transmembrane helices and occurs three times in each of the family member proteins.; putative integral membrane protein 835753..836553 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175756 YP_001221483.1 CDS CMM_0743 NC_009480.1 836550 837290 D conserved hypothetical protein, putative epimerase (CAB09457.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_827106.1| hypothetical protein SAV5929 [Streptomyces avermitilis MA-4680]). InterPro: Phenazine biosynthesis PhzC/PhzF protein pfam02567, PhzC-PhzF, Phenazine biosynthesis-like protein. PhzF_family: phenazine biosynthesis pro; Function unclear; hypothetical protein 836550..837290 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175254 YP_001221484.1 CDS CMM_0744 NC_009480.1 837317 838630 R conserved membrane protein (NP_736814.1| putative transport protein [Corynebacterium efficiens YS-314]; ZP_00121591.2| COG1253: Hemolysins and related proteins containing CBS domains [Bifidobacterium longum DJO10A]). ,pfam01595, DUF21, Domain of unknown function DUF21. This transmembrane region has no known function. , pfam00571,CBS, CBS domain. CBS domains are small intracellular modules of unknown function. They are mostly found in 2 or four copies within a protein. (twice). pfam03471,CorC_HlyC, Transporter associated domain. This small domain is found in a family of proteins with the pfam01595 domain and two CBS domains with this domain found at the C-terminus of the proteins, the domain is also found at the C terminus of some Na+/H+ antiporters. This domain is also found in CorC that is involved in Magnesium and cobalt efflux. The function of this domain is uncertain but might be involved in modulating transport of ion substrates.; Family membership; hypothetical protein complement(837317..838630) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175378 YP_001221485.1 CDS CMM_0745 NC_009480.1 838844 839251 D Hypothetical protein; hypothetical protein 838844..839251 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175561 YP_001221486.1 CDS prkA NC_009480.1 839279 839833 R putative phosphoribulokinase (Phosphopentokinase) (P37101|KPPR_SYNY3 Phosphoribulokinase (Phosphopentokinase) (PRK); ZP_00109191.1| COG0572: Uridine kinase [Nostoc punctiforme]). pfam00485, PRK,Phosphoribulokinase / Uridine kinase family.; Specificity unclear; putative phosphoribulokinase complement(839279..839833) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173124 YP_001221487.1 CDS CMM_0747 NC_009480.1 839902 840855 R putative dioxygenase (ZP_00226029.1| COG3485: Protocatechuate 3,4-dioxygenase beta subunit [Kineococcus radiotolerans SRS30216]; CAF18808.1| 3,4-dioxygenase beta subunit [Corynebacterium glutamicum ATCC 13032]).,pfam00775, Dioxygenase_C, Dioxygenase.; Specificity unclear; putative dioxygenase complement(839902..840855) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175163 YP_001221488.1 CDS CMM_0748 NC_009480.1 840974 842203 R putative monooxygenase (NP_641998.1| oxidoreductase [Xanthomonas axonopodis pv. citri str. 306]; NP_624584.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]).,pfam01360, Monooxygenase, Monooxygenase. This family includes diverse enzymes that utilise FAD., InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase).; Specificity unclear; putative monooxygenase complement(840974..842203) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175410 YP_001221489.1 CDS CMM_0749 NC_009480.1 842313 842807 D putative transcriptional regulator, MarR family (NP_625140.1| putative marR-family transcriptional regulator [Streptomyces coelicolor A3(2)]; CAF19334.1| transcriptional regulator, MarR family [Corynebacterium glutamicum ATCC 13032]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 842313..842807 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175564 YP_001221490.1 CDS CMM_0750 NC_009480.1 842826 843623 R putative glycosyl transferase (NP_792926.1| glycosyl transferase, group 2 family protein [Pseudomonas syringae pv. tomato str. DC3000]; NP_745399.1| glycosyl transferase, group 2 family protein [Pseudomonas putida KT2440]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose,dolichol phosphate and teichoic acids.; Function unclear; putative glycosyl transferase complement(842826..843623) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175156 YP_001221491.1 CDS CMM_0751 NC_009480.1 843620 846349 R conserved hypothetical protein, acyl-CoA dehydrogenase/methyltransferase multidomain protein: N-terminal (AA 150-350) putative acyl-CoA dehydrogenase (COG1960, CaiA, Acyl-CoA dehydrogenases) (NP_962172.1| hypothetical protein MAP3238 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_745402.1| acyl-CoA dehydrogenase-related protein [Pseudomonas putida KT2440]); AA 475-700 COG2120, COG2120, Uncharacterized proteins, LmbE homologs (NP_962173.1| hypothetical protein MAP3239 [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00265336.1| COG2120: Uncharacterized proteins,LmbE homologs [Pseudomonas fluorescens PfO-1]); C-terminal (AA 720-850) putative methyltransferase (pfam05401, NodS,Nodulation protein S (NodS)(ZP_00284505.1| COG0500: SAM-dependent methyltransferases [Burkholderia fungorum LB400]; NP_745400.1| methyltransferase, putative [Pseudomonas putida KT2440]).; Function unclear; acyl-CoA dehydrogenase/methyltransferase complement(843620..846349) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174563 YP_001221492.1 CDS CMM_0752 NC_009480.1 846449 846667 D putative hypothetical protein; hypothetical protein 846449..846667 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174991 YP_001221493.1 CDS purC NC_009480.1 846755 847675 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(846755..847675) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175530 YP_001221494.1 CDS purD NC_009480.1 847672 848922 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(847672..848922) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175892 YP_001221495.1 CDS CMM_0755 NC_009480.1 849311 849691 D conserved hypothetical protein (AAT89946.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225567.1| hypothetical protein Krad06004784 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 849311..849691 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174455 YP_001221496.1 CDS CMM_0756 NC_009480.1 849751 850059 D putative membrane protein (YP_063050.1| hypothetical protein Lxx22770 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 849751..850059 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174899 YP_001221497.1 CDS purF NC_009480.1 850126 851586 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(850126..851586) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175706 YP_001221498.1 CDS purM NC_009480.1 851676 852785 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 851676..852785 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174092 YP_001221499.1 CDS CMM_0759 NC_009480.1 852922 853131 R conserved hypothetical protein (AAT89942.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_302445.1| conserved hypothetical protein [Mycobacterium leprae]).; hypothetical protein complement(852922..853131) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173132 YP_001221500.1 CDS CMM_0760 NC_009480.1 853341 854471 D putative FAD-dependant monooxygenase/oxidoreductase (YP_063046.1| flavine-dependent monooxygenase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625435.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]). pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain. InterPro: NAD binding site; Function unclear; putative FAD-dependent oxidoreductase 853341..854471 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174687 YP_001221501.1 CDS CMM_0761 NC_009480.1 854801 856861 R putative amino acid permease, APC family (AAR90221.1| putative membrane protein [Rhodococcus sp. DK17]; NP_825951.1| putative membrane protein [Streptomyces avermitilis MA-4680]). pfam00324,AA_permease, Amino acid permease. InterPro: Permease for amino acids and related compounds family I.; Specificity unclear; amino acid permease complement(854801..856861) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174049 YP_001221502.1 CDS CMM_0762 NC_009480.1 856950 857615 R conserved membrane protein (NP_625700.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00057925.1| COG2364: Predicted membrane protein [Thermobifida fusca]). pfam02588, DUF161,Uncharacterized BCR, YitT family COG1284. This is probably a bacterial ABC transporter permease (personal obs:Yeats C). (twice).; Function unclear; hypothetical protein complement(856950..857615) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174817 YP_001221503.1 CDS CMM_0763 NC_009480.1 857678 859141 D putative transcriptional regulator containing a DNA-binding HTH domain and an aminotransferase domain (ZP_00228006.1| COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Kineococcus radiotolerans SRS30216]; NP_828105.1| putative GntR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00392,GntR, Bacterial regulatory proteins, gntR family. pfam00155, Aminotran_1_2, Aminotransferase class I and II.; Function unclear; transcriptional regulator 857678..859141 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174302 YP_001221504.1 CDS ppaF NC_009480.1 859301 860284 D putative extracellular serine protease, glutamyl endopeptidase (ZP_00227464.1| COG3591: V8-like Glu-specific endopeptidase [Kineococcus radiotolerans SRS30216]; NP_297821.1| hypothetical protein [Xylella fastidiosa 9a5c]).; Function unclear; hypothetical protein 859301..860284 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174691 YP_001221505.1 CDS CMM_0765 NC_009480.1 860397 862478 D putative glycogen debranching enzyme (ZP_00228190.1| COG1523: Type II secretory pathway,pullulanase PulA and related glycosidases [Kineococcus radiotolerans SRS30216]; YP_061380.1| glycogen debranching enzyme [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00128, Alpha-amylase, Alpha amylase,catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases.; Specificity unclear; putative glycogen debranching enzyme 860397..862478 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174225 YP_001221506.1 CDS CMM_0766 NC_009480.1 862605 863672 D conserved membrane protein (NP_295927.1| conserved hypothetical protein [Deinococcus radiodurans R1]; NP_281741.1| putative integral membrane protein [Campylobacter jejuni subsp.jejuni NCTC 11168]).; Function unclear; hypothetical protein 862605..863672 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175686 YP_001221507.1 CDS CMM_0767 NC_009480.1 863669 864067 R hypothetical protein (YP_062777.1| hypothetical protein Lxx19520 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(863669..864067) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175330 YP_001221508.1 CDS CMM_0768 NC_009480.1 864085 864483 R hypothetical protein (ZP_00228438.1| COG4338: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; ZP_00267705.1| COG0117: Pyrimidine deaminase [Rhodospirillum rubrum]; ZP_00328354.1| COG4338: Uncharacterized protein conserved in bacteria [Trichodesmium erythraeum IMS101]). weak similarity to: COG4338, Uncharacterized protein conserved in bacteria [Function unknown].; hypothetical protein complement(864085..864483) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175160 YP_001221509.1 CDS CMM_0769 NC_009480.1 864672 867941 D putative integral membrane efflux protein, RND family (NP_827216.1| putative integral membrane efflux protein [Streptomyces avermitilis MA-4680]; ZP_00330620.1| COG0841: Cation/multidrug efflux pump [Moorella thermoacetica ATCC 39073]). pfam00873, ACR_tran,AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.; Specificity unclear; RND family mulitdrug efflux protein 864672..867941 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174822 YP_001221510.1 CDS CMM_0770 NC_009480.1 869280 870491 D putative RNA helicase (YP_062998.1| ATP-dependent RNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227011.1| COG0513: Superfamily II DNA and RNA helicases [Kineococcus radiotolerans SRS30216]). 25466,pfam00270, DEAD, DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Function unclear; putative ATP-dependent RNA helicase 869280..870491 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173401 YP_001221511.1 CDS CMM_0771 NC_009480.1 870534 871118 D putative acetyltransferase (ZP_00227685.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Kineococcus radiotolerans SRS30216]; ZP_00086502.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Pseudomonas fluorescens PfO-1]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 870534..871118 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173649 YP_001221512.1 CDS CMM_0772 NC_009480.1 871152 871655 D putative acetyltransferase (ZP_00226643.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Kineococcus radiotolerans SRS30216]; NP_828437.1| putative acetyltransferase [Streptomyces avermitilis MA-4680]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 871152..871655 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175528 YP_001221513.1 CDS CMM_0773 NC_009480.1 871708 872181 D Hypothetical protein; hypothetical protein 871708..872181 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175105 YP_001221514.1 CDS CMM_0774 NC_009480.1 872320 873297 D putative sugar kinase (BAB97551.1| Sugar kinases,ribokinase family [Corynebacterium glutamicum ATCC 13032]; ZP_00226213.1| COG0524: Sugar kinases, ribokinase family [Kineococcus radiotolerans SRS30216]). pfam00294,PfkB, pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases.; Specificity unclear; putative sugar kinase 872320..873297 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175673 YP_001221515.1 CDS CMM_0775 NC_009480.1 873294 874235 D conserved hypothetical protein, putative aldolase (CAF18726.1| conserved hypothetical protein [Corynebacterium glutamicum ATCC 13032]; ZP_00226214.1| hypothetical protein Krad06003760 [Kineococcus radiotolerans SRS30216]).; Function unclear; putative aldolase 873294..874235 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174913 YP_001221516.1 CDS CMM_0776 NC_009480.1 874289 875794 D putative NAD-dependent aldehyde dehydrogenase (NP_599412.1| NAD-dependent aldehyde dehydrogenase [Corynebacterium glutamicum ATCC 13032]; ZP_00226521.1| COG1012: NAD-dependent aldehyde dehydrogenases [Kineococcus radiotolerans SRS30216]). pfam00171, Aldedh,Aldehyde dehydrogenase family. InterPro: Aldehyde dehydrogenase family; Specificity unclear; putative NAD-dependent aldehyde dehydrogenase 874289..875794 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174559 YP_001221517.1 CDS CMM_0777 NC_009480.1 875854 876780 D conserved hypothetical protein involved in inositol metabolism (CAF18728.1| enzyme involved in inositol metabolism [Corynebacterium glutamicum ATCC 13032]; NP_631041.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam06845, IolB, Myo-inositol catabolism protein IolB. This family consists of several bacterial Myo-inositol catabolism (IolB) proteins.The exact function of IolB is unknown.; High confidence in function and specificity; hypothetical protein 875854..876780 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175236 YP_001221518.1 CDS CMM_0778 NC_009480.1 876777 878693 D putative acetolactate synthase (CAF18729.1| PUTATIVE ACETOLACTATE SYNTHASE PROTEIN [Corynebacterium glutamicum ATCC 13032]; ZP_00226216.1| COG3962: Acetolactate synthase [Kineococcus radiotolerans SRS30216]). pfam02776, TPP_enzyme_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. pfam00205, TPP_enzyme_M, Thiamine pyrophosphate enzyme,central domain. pfam02775, TPP_enzyme_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. acolac_lg: acetolactate synthase larg; Specificity unclear; putative acetolactate synthase 876777..878693 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173059 YP_001221519.1 CDS CMM_0779 NC_009480.1 878806 879132 R hypothetical protein complement(878806..879132) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173381 YP_001221520.1 CDS CMM_0780 NC_009480.1 879560 880537 D putative sugar phosphate isomerase/epimerase (NP_438000.1| HYPOTHETICAL PROTEIN SMb20768 [Sinorhizobium meliloti 1021]; ZP_00228598.1| COG3623: Putative L-xylulose-5-phosphate 3-epimerase [Kineococcus radiotolerans SRS30216]). COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]. hxl6Piso_put: hexulose-6-phosphate is; Specificity unclear; putative sugar phosphate isomerase/epimerase 879560..880537 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173074 YP_001221521.1 CDS CMM_0781 NC_009480.1 880534 881502 D putative 3-hydroxyacyl-CoA dehydrogenase (ZP_00228602.1| COG1250: 3-hydroxyacyl-CoA dehydrogenase [Kineococcus radiotolerans SRS30216]; ZP_00298783.1| COG1250: 3-hydroxyacyl-CoA dehydrogenase [Geobacter metallireducens GS-15]). pfam02737, 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. pfam00725, 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain.; Specificity unclear; putative 3-hydroxyacyl-CoA dehydrogenase 880534..881502 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175715 YP_001221522.1 CDS CMM_0782 NC_009480.1 881536 882285 R putative oxidoreductase (NP_793827.1| oxidoreductase, short-chain dehydrogenase/reductase family [Pseudomonas syringae pv. tomato str. DC3000]; NP_631846.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. TIGR00301: NADP oxidoreductase coenzym; Function unclear; putative oxidoreductase complement(881536..882285) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174279 YP_001221523.1 CDS CMM_0783 NC_009480.1 882419 883261 D putative transcriptional regulator, Cro/CI family (ZP_00226903.1| COG1396: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]; NP_631845.1| putative DNA-binding protein [Streptomyces coelicolor A3(2)]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator 882419..883261 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175629 YP_001221524.1 CDS CMM_0784 NC_009480.1 883362 884003 D Hypothetical protein; hypothetical protein 883362..884003 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174318 YP_001221525.1 CDS CMM_0785 NC_009480.1 884011 884700 R putative transcriptional regulator, GntR family (ZP_00196672.1| hypothetical protein MBNC415202 [Mesorhizobium sp. BNC1]; NP_435388.1| putative GntR-family regulator [Sinorhizobium meliloti 1021]). pfam00392, GntR, Bacterial regulatory proteins, gntR family. This domain comprises the N-terminal HTH-containing region of GntR-like bacterial transcription factors. At the C terminus there is usually an effector-binding/oligomerisation domain.; Specificity unclear; GntR family transcriptional regulator complement(884011..884700) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174001 YP_001221526.1 CDS tpiB NC_009480.1 884749 885546 R putative triosephosphate isomerase (NP_624890.1| putative triosephosphate isomerase [Streptomyces coelicolor A3(2)]; YP_048976.1| putative triosephosphate isomerase [Erwinia carotovora subsp. atroseptica SCRI1043]). , pfam00121, TIM, Triosephosphate isomerase.; High confidence in function and specificity; putative triosephosphate isomerase complement(884749..885546) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173030 YP_001221527.1 CDS rpiB NC_009480.1 885551 886012 R putative ribose 5-phosphate isomerase (NP_624891.1| putative ribose 5-phosphate isomerase [Streptomyces coelicolor A3(2)]; XP_456866.1| unnamed protein product [Debaryomyces hansenii]). , pfam02502, LacAB_rpiB,Ribose/Galactose Isomerase. InterPro: Ribose/Galactose Isomerase.; High confidence in function and specificity; putative ribose 5-phosphate isomerase complement(885551..886012) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175792 YP_001221528.1 CDS dakA NC_009480.1 886062 887798 R in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone; dihydroxyacetone kinase complement(886062..887798) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172945 YP_001221529.1 CDS CMM_0789 NC_009480.1 887879 888640 R putative transcriptional regulator, GntR family (CAF18724.1| Bacterial regulatory proteins, gntR family [Corynebacterium glutamicum ATCC 13032]; NP_823160.1| putative GntR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00392, GntR,Bacterial regulatory proteins, gntR family. This domain comprises the N-terminal HTH-containing region of GntR-like bacterial transcription factors. At the C terminus there is usually an effector-binding/oligomerisation domain. InterPro: Bacterial regulatory proteins GntR family.; Specificity unclear; GntR family transcriptional regulator complement(887879..888640) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174588 YP_001221530.1 CDS CMM_0790 NC_009480.1 888694 889623 R putative sugar ABC transporter ATP-binding protein (NP_630359.1| probable ABC sugar transport ATP binding protein [Streptomyces coelicolor A3(2)]; ZP_00226220.1| COG1129: ABC-type sugar transport system, ATPase component [Kineococcus radiotolerans SRS30216]). pfam00005,ABC_tran, ABC transporter.; Specificity unclear; putative sugar ABC transporter ATP-binding protein complement(888694..889623) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173546 YP_001221531.1 CDS CMM_0791 NC_009480.1 889620 890663 R putative sugar ABC transporter, permease component (NP_631045.1| probable ABC transport protein, membrane component. [Streptomyces coelicolor A3(2)]; ZP_00226219.1| COG1172: Ribose/xylose/arabinose/ galactoside ABC-type transport systems, permease components [Kineococcus radiotolerans SRS30216]). pfam02653, BPD_transp_2, Branched-chain amino acid transport system / permease component. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families); Specificity unclear; putative sugar ABC transporter permease complement(889620..890663) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172971 YP_001221532.1 CDS CMM_0792 NC_009480.1 890768 891745 R putative sugar ABC transporter, solute-binding protein (NP_631044.1| probable solute-binding lipoprotein. [Streptomyces coelicolor A3(2)]; ZP_00226218.1| COG1879: ABC-type sugar transport system, periplasmic component [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative sugar ABC transporter solute-binding protein complement(890768..891745) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174075 YP_001221533.1 CDS CMM_0793 NC_009480.1 892001 893008 R putative myo-inositol dehydrogenase (ZP_00199086.2| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_602254.1| myo-inositol dehydrogenase [Corynebacterium glutamicum ATCC 13032]). pfam01408, GFO_IDH_MocA, Oxidoreductase family,NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD. pfam02894, GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain.; Specificity unclear; putative myo-inositol dehydrogenase complement(892001..893008) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175140 YP_001221534.1 CDS CMM_0794 NC_009480.1 893068 893985 R putative sugar epimerase (ZP_00200300.1| COG1082: Sugar phosphate isomerases/epimerases [Rubrobacter xylanophilus DSM 9941]; ZP_00092855.1| COG1082: Sugar phosphate isomerases/epimerases [Azotobacter vinelandii]; NP_519368.1| PUTATIVE MYO-INOSITOL CATABOLISM PROTEIN [Ralstonia solanacearum]).; Function unclear; putative sugar epimerase complement(893068..893985) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172961 YP_001221535.1 CDS CMM_0795 NC_009480.1 894292 896427 D putative extracellular nuclease/phosphatase (NP_601790.1| predicted extracellular nuclease [Corynebacterium glutamicum ATCC 13032]; NP_927023.1| hypothetical protein gll4077 [Gloeobacter violaceus]). pfam03372, Exo_endo_phos,Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling.; Function unclear; putative extracellular nuclease/phosphatase 894292..896427 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173256 YP_001221536.1 CDS trxC NC_009480.1 896513 896914 D putative thioredoxin (ZP_00292263.1| COG0526: Thiol-disulfide isomerase and thioredoxins [Thermobifida fusca]; NP_739422.1| putative thioredoxin [Corynebacterium efficiens YS-314]). Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. pfam00085,Thioredoxin, Thioredoxin. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond. InterPro: Thioredoxin.; High confidence in function and specificity; putative thioredoxin 896513..896914 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173751 YP_001221537.1 CDS recQ3 NC_009480.1 897027 898910 D putative ATP-dependent DNA helicase (YP_062975.1| ATP-dependent DNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628739.1| putative helicase [Streptomyces coelicolor A3(2)]). pfam00270, DEAD,DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. pfam00271, Helicase_C,Helicase conserved C-terminal domain. pfam00570, HRDC,HRDC domain. The HRDC (Helicase and RNase D C-terminal) domain has a putative role in nucleic acid binding.; Specificity unclear; putative ATP-dependent DNA helicase 897027..898910 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174923 YP_001221538.1 CDS CMM_0798 NC_009480.1 899312 901318 D conserved hypothetical protein (ZP_00228010.1| COG3533: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_228092.1| hypothetical protein [Thermotoga maritima]).; Function unclear; hypothetical protein 899312..901318 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173345 YP_001221539.1 CDS bldKB NC_009480.1 901468 903150 D putative oligopeptide ABC transporter, substrate-binding lipoprotein (NP_629263.1| BldKB, putative ABC transport system lipoprotein [Streptomyces coelicolor A3(2)]; ZP_00294235.1| COG0747: ABC-type dipeptide transport system, periplasmic component [Thermobifida fusca]). This protein is a component of the oligopeptide permease, a binding protein-dependent transport system It binds peptides up small peptides with high affinity. Also required for sporulation and competence. pfam00496,SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative oligopeptide ABC transporter substrate-binding lipoprotein 901468..903150 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174539 YP_001221540.1 CDS bldKA NC_009480.1 903154 904116 D putative oligopeptide ABC transporter, permease component (ZP_00059564.1| COG1173: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Thermobifida fusca]; NP_629262.1| BldKA,putative ABC transport system integral membrane protein [Streptomyces coelicolor A3(2)]). Part of the binding-protein-dependent transport system for peptides; probably responsible for the translocation of the substrate across the membrane. pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative oligopeptide ABC transporter permease 903154..904116 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173204 YP_001221541.1 CDS bldKC NC_009480.1 904113 905105 D putative peptide ABC transporter, permease component (ZP_00059566.1| COG0601: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Thermobifida fusca]; NP_629264.1| BldKC,putative ABC transport system integral membrane protein [Streptomyces coelicolor A3(2)]). InterPro: Binding-protein-dependent transport systems inner membrane component. pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative peptide ABC transporter permease 904113..905105 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173679 YP_001221542.1 CDS bldKD NC_009480.1 905102 905968 D putative peptide ABC transporter, ATP-binding protein (NP_824329.1| putative ABC transporter intracellular ATPase BldKD [Streptomyces avermitilis MA-4680]; NP_059748.1| moaD [Agrobacterium tumefaciens]). ,, Part of the binding-protein-dependent transport system for peptides. Probably responsible for energy coupling to the transport system., , InterPro: AAA ATPase superfamily pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative peptide ABC transporter ATP-binding protein 905102..905968 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174002 YP_001221543.1 CDS bldKE NC_009480.1 905965 906903 D putative peptide ABC transporter, ATP-binding protein (NP_824330.1| putative ABC transporter ATP-binding protein BldKE [Streptomyces avermitilis MA-4680]; NP_244512.1| oligopeptide ABC transporter (ATP-binding protein) [Bacillus halodurans]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative peptide ABC transporter ATP-binding protein 905965..906903 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173804 YP_001221544.1 CDS pipA NC_009480.1 906900 908207 D putative proline iminopeptidase (Prolyl aminopeptidase)(JC4623 prolyl aminopeptidase (EC 3.4.11.5) - Hafnia alvei; NP_696104.1| proline iminopeptidase [Bifidobacterium longum NCC2705]). InterPro: Esterase/lipase/thioesterase family active site pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Specificity unclear; putative prolyl aminopeptidase 906900..908207 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175301 YP_001221545.1 CDS pepP1 NC_009480.1 908204 909688 D putative Xaa-Pro aminopeptidase (Aminoacylproline aminopeptidase) (NP_696514.1| Xaa-Pro aminopeptidase I [Bifidobacterium longum NCC2705]; NP_625637.1| Xaa-Pro aminopeptidase II (EC 3.4.11.9) [Streptomyces coelicolor A3(2)]). , pfam05195, AMP_N, Aminopeptidase P, N-terminal domain. , pfam00557, Peptidase_M24, metallopeptidase family M24.; High confidence in function and specificity; putative Xaa-Pro aminopeptidase 908204..909688 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173703 YP_001221546.1 CDS CMM_0806 NC_009480.1 909706 910419 D putative transcriptional regulator, GntR-family (NP_822905.1| putative GntR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_879291.1| putative GntR-family transcriptional regulator [Bordetella pertussis Tohama I]). pfam00392,GntR, Bacterial regulatory proteins, gntR family. This domain comprises the N-terminal HTH-containing region of GntR-like bacterial transcription factors. At the C terminus there is usually an effector-binding/oligomerisation domain.; Specificity unclear; GntR family transcriptional regulator 909706..910419 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175056 YP_001221547.1 CDS CMM_0807 NC_009480.1 910532 911776 D putative secreted D-amino acid oxidase (NP_630387.1| putative secreted oxidoreductase [Streptomyces coelicolor A3(2)]; NP_832586.1| Sarcosine oxidase beta subunit [Bacillus cereus ATCC 14579]). pfam01266, DAO, FAD dependent oxidoreductase. This family includes various FAD dependent oxidoreductases.; Specificity unclear; putative secreted D-amino acid oxidase 910532..911776 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173375 YP_001221548.1 CDS CMM_0808 NC_009480.1 911773 912111 D conserved hypothetical protein, putative D-amino acid oxidase subunit (NP_822909.1| hypothetical protein SAV1733 [Streptomyces avermitilis MA-4680]; NP_832589.1| Sarcosine oxidase alpha subunit [Bacillus cereus ATCC 14579]). weak similarity to COG3383, Uncharacterized anaerobic dehydrogenase; hypothetical protein 911773..912111 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173151 YP_001221549.1 CDS CMM_0809 NC_009480.1 912108 913799 D putative amino acid oxidase (NP_630389.1| putative secreted oxidase [Streptomyces coelicolor A3(2)]; AAQ87569.1| Opine oxidase subunit A [Rhizobium sp. NGR234]; AAC38595.1| hydrogen cyanide synthase HcnB [Pseudomonas fluorescens]) pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain. pfam04324, Fer2_BFD, BFD-like [2Fe-2S] binding domain. The two Fe ions are each coordinated by two conserved cysteine residues.; Function unclear; putative amino acid oxidase 912108..913799 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175641 YP_001221550.1 CDS dapX NC_009480.1 913796 914713 D putative dihydrodipicolinate synthase (NP_822907.1| putative dihydrodipicolinate synthase [Streptomyces avermitilis MA-4680]; NP_797714.1| probable dihydrodipicolinate synthetase [Vibrio parahaemolyticus RIMD 2210633]). pfam00701, DHDPS, Dihydrodipicolinate synthetase family. This family has a TIM barrel structure.; High confidence in function and specificity; dihydrodipicolinate synthase 913796..914713 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173083 YP_001221551.1 CDS CMM_0811 NC_009480.1 914721 915722 D putative proline racemase (NP_822906.1| putative proline racemase [Streptomyces avermitilis MA-4680]; NP_845180.1| proline racemase, putative [Bacillus anthracis str. Ames]). pfam05544, Pro_racemase, Proline racemase. This family consists of proline racemase (EC 5.1.1.4) proteins which catalyse the interconversion of L-and D-proline in bacteria.; High confidence in function and specificity; putative proline racemase 914721..915722 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174858 YP_001221552.1 CDS CMM_0812 NC_009480.1 915749 917269 D putative aldehyde dehydrogenase (AAR90163.1| putative aldehyde dehydrogenase [Rhodococcus sp. DK17]; NP_827565.1| putative aldehyde dehydrogenase [Streptomyces avermitilis MA-4680]). InterPro: Aldehyde dehydrogenase family pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor.; Specificity unclear; putative aldehyde dehydrogenase 915749..917269 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173343 YP_001221553.1 CDS CMM_0813 NC_009480.1 917535 919640 D putative acyl-CoA oxidase (YP_062974.1| acyl-CoA oxidase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058724.1| COG1960: Acyl-CoA dehydrogenases [Thermobifida fusca]). pfam02770, Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain. pfam00441, Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain. pfam01756, ACOX,Acyl-CoA oxidase. This is a family of Acyl-CoA oxidases EC:1.3.3.6. Acyl-coA oxidase converts acyl-CoA into trans-2- enoyl-CoA.; Specificity unclear; putative acyl-CoA oxidase 917535..919640 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173105 YP_001221554.1 CDS CMM_0814 NC_009480.1 919711 920055 R putative growth inhibitor (NP_713024.1| chpK [Leptospira interrogans serovar lai str. 56601]; CAA98393.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam02452, PemK, PemK-like protein. PemK is a growth inhibitor in E. Coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis.; Function unclear; putative growth inhibitor complement(919711..920055) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173760 YP_001221555.1 CDS CMM_0815 NC_009480.1 920052 920303 R putative transcriptional regulator, CopG family(NP_336510.1| DNA-binding protein, CopG family [Mycobacterium tuberculosis CDC1551]; NP_713025.1| ChpI protein [Leptospira interrogans serovar lai str. 56601]). pfam01402, HTH_4, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerisation and not DNA binding as might have been expected.; Conserved hypothetical protein; CopG family transcriptional regulator complement(920052..920303) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173445 YP_001221556.1 CDS CMM_0816 NC_009480.1 920376 921158 R putative esterase, lysophospholipase (ZP_00213268.1| COG2755: Lysophospholipase L1 and related esterases [Burkholderia cepacia R18194]; ZP_00137144.2| COG2755: Lysophospholipase L1 and related esterases [Pseudomonas aeruginosa UCBPP-PA14]; NP_215591.1| hypothetical protein Rv1075c [Mycobacterium tuberculosis H37Rv]).; Family membership; putative esterase, lysophospholipase complement(920376..921158) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173202 YP_001221557.1 CDS pipB NC_009480.1 921336 922304 D Proline iminopeptidase (Prolyl aminopeptidase) (YP_062972.1| prolyl aminopeptidase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058619.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Thermobifida fusca]). SPECIFICALLY CATALYZES THE REMOVAL OF N-TERMINAL PROLINE RESIDUES FROM PEPTIDES. pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; High confidence in function and specificity; proline iminopeptidase 921336..922304 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173207 YP_001221558.1 CDS tagD NC_009480.1 922323 922820 R putative glycerol-3-phosphate cytidylyltransferase (ZP_00227149.1| COG0615: Cytidylyltransferase [Kineococcus radiotolerans SRS30216]; NP_213944.1| glycerol-3-phosphate cytidyltransferase [Aquifex aeolicus]). pfam01467, CTP_transf_2, Cytidylyltransferase. This family includes: Cholinephosphate cytidylyltransferase, Glycerol-3-phosphate cytidylyltransferase. InterPro: Cytidylyltransferase.; Function unclear; glycerol-3-phosphate cytidylyltransferase complement(922323..922820) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173651 YP_001221559.1 CDS wcoA NC_009480.1 923198 925816 D putative cell surface protein, potentially involved in polysaccharide synthesis (only weak similarities to sugar transferases, endoglucanases and RTX toxins; NP_631284.1| putative polysaccharide lyase [Streptomyces coelicolor A3(2)).; Function unclear; putative cell surface protein 923198..925816 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174712 YP_001221560.1 CDS wcoB NC_009480.1 926113 928713 D hypothetical protein potentially involved in polysaccharide metabolism (only weak similarities to glucanases, RTX toxins; NP_680916.1| ORF_ID:tlr0125 unknown protein [Thermosynechococcus elongatus BP-1]; NP_631284.1| putative polysaccharide lyase [Streptomyces coelicolor A3(2)]). InterPro: Proline-rich region; Function unclear; hypothetical protein 926113..928713 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173258 YP_001221561.1 CDS wcoC NC_009480.1 929197 930732 D putative undecaprenyl-phosphate sugar phosphotransferase (NP_959898.1| hypothetical protein MAP0964c [Mycobacterium avium subsp. paratuberculosis str. k10]; AAM94041.1| putative undecaprenyl-phosphate glycosyl-1-phosphate transferase; glucose-1-phosphate transferase [Streptomyces sp. 139]). Contains two domains,N-terminal: COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases; pfam02719, Polysacc_synt_2,Polysaccharide biosynthesis protein. C-terminal: COG2148,WcaJ, Sugar transferases involved in lipopolysaccharide synthesis; pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.; Specificity unclear; putative undecaprenyl-phosphate sugar phosphotransferase 929197..930732 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173280 YP_001221562.1 CDS wcoD NC_009480.1 930734 931966 D putative glycosyltransferase (ZP_00081740.1| COG0438: Glycosyltransferase [Geobacter metallireducens]; CAC18356.1| putative rhamnosyltransferase [Streptococcus salivarius]). pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides.; Specificity unclear; putative glycosyltransferase 930734..931966 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173300 YP_001221563.1 CDS wcoE NC_009480.1 931963 932790 D putative phosphatidylglycerophosphate synthase (ZP_00227148.1| COG2870: ADP-heptose synthase,bifunctional sugar kinase/ adenylyltransferase [Kineococcus radiotolerans SRS30216]; NP_823318.1| hypothetical protein [Streptomyces avermitilis MA-4680]; ZP_00057237.1| COG0558: Phosphatidylglycerophosphate synthase [Thermobifida fusca]). pfam01066, CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase.; Specificity unclear; putative phosphatidylglycerophosphate synthase 931963..932790 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173339 YP_001221564.1 CDS wcoF NC_009480.1 932787 934028 D putative glycosyl transferase (NP_103517.1| unknown protein [Mesorhizobium loti MAFF303099]; AAN64562.1| glycosyltransferase [Streptococcus gordonii]). pfam00534,Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides.; Function unclear; putative glycosyltransferase 932787..934028 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173361 YP_001221565.1 CDS wcoG NC_009480.1 934078 939963 D hypothetical protein (only weak similarities to collagenases, glucanases and RTX toxins; ZP_00227150.1| hypothetical protein Krad06001747 [Kineococcus radiotolerans SRS30216]; ZP_00116912.1| COG3468: Type V secretory pathway, adhesin AidA [Cytophaga hutchinsonii]; NP_518236.1| PUTATIVE HEMAGGLUTININ-RELATED PROTEIN [Ralstonia solanacearum]). pfam00801, PKD, PKD domain.; Function unclear; putative cell surface protein 934078..939963 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173372 YP_001221566.1 CDS wcoH NC_009480.1 940128 941498 D Hypothetical protein; hypothetical protein 940128..941498 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173412 YP_001221567.1 CDS wcoI NC_009480.1 941495 942883 D putative capsular polysaccharide synthesis enzyme (CAF19058.1| cell surface polysaccharide biosynthesis / Chain length determinant protein [Corynebacterium glutamicum ATCC 13032]; NP_696399.1| possible Etk- like tyrosine kinase involved in Eps biosynthesis [Bifidobacterium longum NCC2705]). , Contains two domains. N-terminal: COG3944, Capsular polysaccharide biosynthesis protein; pfam02706, Wzz, Chain length determinant protein. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. , C-terminal: COG0489, Mrp, ATPases involved in chromosome partitioning; Specificity unclear; capsular polysaccharide synthesis enzyme 941495..942883 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173395 YP_001221568.1 CDS CMM_0828 NC_009480.1 943579 944319 D hypothetical protein (CAI37418.1| putative DNA restriction-modification system, hypothetical protein [Corynebacterium jeikeium K411]; NP_862180.1| hypothetical protein [Streptomyces violaceoruber]).; hypothetical protein 943579..944319 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175775 YP_001221569.1 CDS wcoK NC_009480.1 946682 947329 R hypothetical protein, putative membrane protein; hypothetical protein complement(946682..947329) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173077 YP_001221570.1 CDS CMM_0830 NC_009480.1 947529 949463 R Region start changed from 949550 to 949463 (-87 bases); putative glycosyltransferase complement(947529..949463) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173396 YP_001221571.1 CDS wcoM NC_009480.1 949624 950673 D putative glycosyl transferase (NP_637800.1| GumI protein [Xanthomonas campestris pv. campestris str. ATCC 33913] ; ZP_00228119.1| COG0438: Glycosyltransferase [Kineococcus radiotolerans SRS30216]). pfam00534,Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP,ADP, GDP or CMP linked sugars.; Specificity unclear; putative glycosyl transferase 949624..950673 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173325 YP_001221572.1 CDS wzx3 NC_009480.1 950845 952464 D putative membrane protein involved in the export of polysaccharides, MOP family (NP_637799.1| GumJ protein [Xanthomonas campestris pv. campestris str. ATCC 33913]; ZP_00039159.1| COG2244: Membrane protein involved in the export of O-antigen and teichoic acid [Xylella fastidiosa Dixon]; CAF19065.1| putative translocase involved in export of a cell surface polysaccaride [Corynebacterium glutamicum ATCC 13032]). , , pfam01943, Polysacc_synt,Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. InterPro: Polysaccharide biosynthesis protein.; Specificity unclear; putative membrane protein involved in the export of polysaccharides 950845..952464 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173481 YP_001221573.1 CDS wcoN NC_009480.1 952628 953671 D putative nucleotide sugar epimerase (ZP_00226592.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; ZP_00064898.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Microbulbifer degradans 2-40]). pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Function unclear; putative nucleotide sugar epimerase 952628..953671 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173971 YP_001221574.1 CDS wcoO NC_009480.1 953701 954522 R conserved membrane protein (ZP_00227474.1| hypothetical protein Krad06004208 [Kineococcus radiotolerans SRS30216]; NP_736959.1| hypothetical protein [Corynebacterium efficiens YS-314]).; Function unclear; hypothetical protein complement(953701..954522) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173447 YP_001221575.1 CDS wcoP NC_009480.1 954603 955109 D putative transcriptional regulator, MarR family (NP_782612.1| transcriptional regulator, marR family [Clostridium tetani E88]; ZP_00058332.1| COG1846: Transcriptional regulators [Thermobifida fusca]). smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein; Specificity unclear; MarR family transcriptional regulator 954603..955109 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173500 YP_001221576.1 CDS wcoQ NC_009480.1 955106 955870 D conserved hypothetical protein (ZP_00198897.1| COG3361: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_625469.1| conserved hypothetical protein SCG11A.10c [Streptomyces coelicolor A3(2)]).; Function unclear; hypothetical protein 955106..955870 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173474 YP_001221577.1 CDS wcoR NC_009480.1 955907 957742 R putative glycosyl hydrolase, family 15 (NP_636453.1| conserved hypothetical protein [Xanthomonas campestris pv. campestris str. ATCC 33913]; NP_733605.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam00723, Glyco_hydro_15, Glycosyl hydrolases family 15.; Specificity unclear; glycoside hydrolase family protein complement(955907..957742) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173525 YP_001221578.1 CDS CMM_0838 NC_009480.1 957982 958515 D conserved hypothetical protein (NP_630535.1| conserved hypothetical protein SC9B5.17 [Streptomyces coelicolor A3(2)]; Q9EYI6|Y189_STRNO Hypothetical 19.0 kDa protein in sno 5'region (ORF7); NP_663093.1| histone macro-H2A1-related protein [Chlorobium tepidum TLS]).; Function unclear; hypothetical protein 957982..958515 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173534 YP_001221579.1 CDS CMM_0839 NC_009480.1 959321 960616 D putative membrane bound metalloprotease (YP_062953.1| cell wall binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00109858.1| COG0739: Membrane proteins related to metalloendopeptidases, family M23 [Nostoc punctiforme]). pfam01551, Peptidase_M37,Peptidase family M23/M37. Members of this family are zinc metallopeptidases with a range of specificities.; Function unclear; putative membrane bound metalloprotease 959321..960616 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174949 YP_001221580.1 CDS CMM_0840 NC_009480.1 960630 962003 D putative membrane associated protein (NP_787277.1| NPL/P60 family secreted protein [Tropheryma whipplei str. Twist]; NP_471978.1| peptidoglycan lytic protein P45 [Listeria innocua]). pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins. InterPro: NLP/P60.; Function unclear; NPL/P60 family secreted protein 960630..962003 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173542 YP_001221581.1 CDS ipyA NC_009480.1 962140 962667 R putative inorganic pyrophosphatase (YP_062951.1| inorganic pyrophosphatase [Leifsonia xyli subsp. xyli str. CTCB07]; O06379|IPYR_MYCTU Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase) (PPase)). pfam00719,Pyrophosphatase, Inorganic pyrophosphatase.; High confidence in function and specificity; hypothetical protein complement(962140..962667) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173289 YP_001221582.1 CDS CMM_0842 NC_009480.1 962722 963747 D putative ATPase of the PP-loop superfamily implicated in cell cycle control (YP_062950.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058801.1| COG0037: Predicted ATPase of the PP-loop superfamily implicated in cell cycle control [Thermobifida fusca]). pfam01171, ATP_bind_3, PP-loop family. This family of proteins belongs to the PP-loop superfamily.; Specificity unclear; putative cell cycle protein 962722..963747 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175049 YP_001221583.1 CDS hptA NC_009480.1 963749 964300 D Hypoxanthine-guanine phosphoribosyltransferase (YP_062949.1| hypoxanthine phosphoribosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825842.1| putative hypoxanthine phosphoribosyltransferase [Streptomyces avermitilis MA-4680]). pfam00156,Pribosyltran, Phosphoribosyl transferase domain. InterPro: Phosphoribosyl transferase; High confidence in function and specificity; hypothetical protein 963749..964300 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175425 YP_001221584.1 CDS ftsH NC_009480.1 964458 966458 D cell division protein, membrane-bound ATP-dependent protease (YP_062948.1| cell division protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226547.1| COG0465: ATP-dependent Zn proteases [Kineococcus radiotolerans SRS30216]. pfam06480, FtsH_ext, FtsH Extracellular. This domain is found in the FtsH family of proteins. FtsH is the only membrane-bound ATP-dependent protease universally conserved in prokaryotes. pfam00004, AAA, ATPase family associated with various cellular activities (AAA). pfam01434, Peptidase_M41, Peptidase family M41.; High confidence in function and specificity; cell division protein, membrane-bound ATP-dependent protease 964458..966458 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175489 YP_001221585.1 CDS folE NC_009480.1 966463 967047 D GTP cyclohydrolase I (YP_062947.1| GTP cyclohydrolase I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_870186.1| GTP cyclohydrolase I [Pirellula sp. 1]). catalytic activity: gtp + 2 h(2)o = formate + 2-amino-4-hydroxy-6- (erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate. pathway: tetrahydrofolate biosynthesis; first step. pfam01227,GTP_cyclohydroI, GTP cyclohydrolase I. folE: GTP cyclohydrolase I; High confidence in function and specificity; hypothetical protein 966463..967047 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173969 YP_001221586.1 CDS folP NC_009480.1 967044 967916 D dihydropteroate synthase (Dihydropteroate pyrophosphorylase)(YP_062946.1| dihydropteroate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293163.1| COG0294: Dihydropteroate synthase and related enzymes [Thermobifida fusca]). pfam00809, Pterin_bind, Pterin binding enzyme.; High confidence in function and specificity; dihydropteroate synthase 967044..967916 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173640 YP_001221587.1 CDS CMM_0847 NC_009480.1 967921 968631 D Hypothetical protein; hypothetical protein 967921..968631 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173654 YP_001221588.1 CDS folBK NC_009480.1 968625 969515 D bifunctional folate synthesis protein [Includes: Dihydroneopterin aldolase (EC 4.1.2.25) (DHNA) and 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) (78- dihydro-6-hydroxymethylpterin pyrophosphokinase)] (NP_696836.1| probable bifunctional folate synthesis protein [includes: dihydroneopterin aldolase (DhnA); 2-amino-4-hydroxy-6-hydroxy- methyldihydropteridine pyrophosphokinase [Bifidobacterium longum NCC2705]; NP_561938.1| bifunctional folate synthesis protein [Clostridium perfringens str. 13]). COG1539, FolB, Dihydroneopterin aldolase [Coenzyme metabolism]; pfam02152, FolB,Dihydroneopterin aldolase. This enzyme EC:4.1.2.25 catalyses the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate. pfam01288, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK).; High confidence in function and specificity; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 968625..969515 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173082 YP_001221589.1 CDS CMM_0849 NC_009480.1 969512 969994 D conserved membrane protein (CAB08939.1| PROBABLE CONSERVED SECRETED PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_940327.1| Putative membrane protein [Corynebacterium diphtheriae]).; Conserved hypothetical protein; hypothetical protein 969512..969994 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173603 YP_001221590.1 CDS CMM_0850 NC_009480.1 970044 970532 D conserved membrane protein (YP_062943.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226554.1| COG3402: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_825854.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). pfam03703, DUF304,Bacterial membrane flanked domain. Domain found in uncharacterised family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices.; hypothetical protein 970044..970532 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173075 YP_001221591.1 CDS CMM_0851 NC_009480.1 970529 972331 D conserved membrane protein (NP_737260.1| hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00226555.1| COG3428: Predicted membrane protein [Kineococcus radiotolerans SRS30216]). three times pfam03703, DUF304, Bacterial membrane flanked domain. Domain found in uncharacterised family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices.; Function unclear; hypothetical protein 970529..972331 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174488 YP_001221592.1 CDS CMM_0852 NC_009480.1 972328 973089 D conserved hypothetical protein (COG5495, COG5495,Uncharacterized conserved protein; ZP_00058789.1| hypothetical protein [Thermobifida fusca]; NP_825863.1| hypothetical protein SAV4686 [Streptomyces avermitilis MA-4680]).; hypothetical protein 972328..973089 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173022 YP_001221593.1 CDS panC NC_009480.1 973132 974010 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 973132..974010 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173054 YP_001221594.1 CDS lysS NC_009480.1 974122 975663 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 974122..975663 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175390 YP_001221595.1 CDS CMM_0855 NC_009480.1 975670 975795 D hypothetical protein 975670..975795 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173629 YP_001221596.1 CDS CMM_0856 NC_009480.1 975817 975999 D hypothetical protein (YP_062937.1| hypothetical protein Lxx21380 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227406.1| hypothetical protein Krad06000875 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 975817..975999 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174032 YP_001221597.1 CDS clpC NC_009480.1 976162 978672 D ATP-dependent protease, ATPase subunit (NP_627581.1| putative Clp-family ATP-binding protease [Streptomyces coelicolor A3(2)]; NP_959395.1| ClpC [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam02861, Clp_N, Clp amino terminal domain (twice). pfam00004, AAA, ATPase family associated with various cellular activities (AAA) (twice). clpX: ATP-dependent Clp protease ATP; High confidence in function and specificity; ATP-dependent protease, ATPase subunit 976162..978672 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173399 YP_001221598.1 CDS galE2 NC_009480.1 978839 979726 D putative UDP-glucose 4-epimerase (ZP_00225979.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; NP_103218.1| UDP-galactose 4-epimerase [Mesorhizobium loti MAFF303099]). pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Specificity unclear; putative UDP-glucose 4-epimerase 978839..979726 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173616 YP_001221599.1 CDS CMM_0859 NC_009480.1 979723 980700 D putative oxidoreductase, aldo/keto reductase family (ZP_00279967.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Burkholderia fungorum LB400]; NP_822773.1| putative aldo/keto reductase [Streptomyces avermitilis MA-4680]). pfam00248,Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.; Function unclear; putative oxidoreductase 979723..980700 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174705 YP_001221600.1 CDS rplJ NC_009480.1 981002 981517 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 981002..981517 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172929 YP_001221601.1 CDS rplL NC_009480.1 981593 981976 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 981593..981976 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173754 YP_001221602.1 CDS CMM_0862 NC_009480.1 982055 983674 R putative transcriptional regulator, C-terminal response regulator domain (ZP_00140987.1| COG2202: FOG: PAS/PAC domain [Pseudomonas aeruginosa UCBPP-PA14]). pfam00196, GerE, Bacterial regulatory proteins, luxR family. InterPro: Bacterial regulatory protein LuxR family.; Function unclear; putative transcriptional regulator complement(982055..983674) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173834 YP_001221603.1 CDS CMM_0863 NC_009480.1 983800 984279 D putative transcriptional regulator, MarR family (CAB02063.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_628214.1| putative marR regulatory protein [Streptomyces coelicolor A3(2)]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 983800..984279 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172959 YP_001221604.1 CDS CMM_0864 NC_009480.1 984361 985593 D putative multidrug efflux MFS permease (O06473|YFMO_BACSU Multidrug efflux protein yfmO; ZP_00226584.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative multidrug efflux MFS permease 984361..985593 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172969 YP_001221605.1 CDS CMM_0865 NC_009480.1 985636 986655 R transcriptional regulator, LacI family (ZP_00048869.2| COG1609: Transcriptional regulators [Magnetospirillum magnetotacticum]; NP_695717.1| probable LacI-type transcriptional regulator [Bifidobacterium longum NCC2705]). pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The periplasmic binding proteins are the primary receptors for chemotaxis and transport of many sugar based solutes.; Specificity unclear; LacI family transcriptional regulator complement(985636..986655) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172943 YP_001221606.1 CDS CMM_0866 NC_009480.1 986970 988334 D putative alpha-glucoside ABC transporter, substrate-binding protein (ZP_00292314.1| COG1653: ABC-type sugar transport system, periplasmic component [Thermobifida fusca]; ZP_00201205.1| COG1653: ABC-type sugar transport system, periplasmic component [Crocosphaera watsonii WH 8501]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative alpha-glucoside ABC transportersubstrate-binding protein 986970..988334 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172991 YP_001221607.1 CDS CMM_0867 NC_009480.1 988471 989442 D putative alpha-glucoside ABC transporter, permease component (ZP_00292313.1| COG1175: ABC-type sugar transport systems, permease components [Thermobifida fusca]; ZP_00201204.1| COG1175: ABC-type sugar transport systems, permease components [Crocosphaera watsonii WH 8501]).; Specificity unclear; putative alpha-glucoside ABC transporterpermease 988471..989442 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172980 YP_001221608.1 CDS CMM_0868 NC_009480.1 989439 990428 D putative alpha-glucoside ABC transport system,permease component (ZP_00058629.1| COG0395: ABC-type sugar transport system, permease component [Thermobifida fusca]; NP_442748.1| membrane bound sugar transport protein [Synechocystis sp. PCC 6803]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative alpha-glucoside ABC transport system,permease 989439..990428 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173046 YP_001221609.1 CDS CMM_0869 NC_009480.1 990551 992431 D ABC transporter consisting of fused permease and ATPase domains (AAF67494.1| NovA [Streptomyces caeruleus]; ZP_00226145.1| COG1132: ABC-type multidrug transport system, ATPase and permease components [Kineococcus radiotolerans SRS30216]). pfam00664,ABC_membrane, ABC transporter transmembrane region. pfam00005, ABC_tran, ABC transporter.; Specificity unclear; ABC transporter permease/ATPase 990551..992431 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173014 YP_001221610.1 CDS CMM_0870 NC_009480.1 992488 993255 R conserved hypothetical protein (AAS20097.1| hypothetical protein [Arthrobacter aurescens]; NP_827127.1| putative secreted protein [Streptomyces avermitilis MA-4680]). pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function (twice). TIGR00729: ribonuclease HII; hypothetical protein complement(992488..993255) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173041 YP_001221611.1 CDS CMM_0871 NC_009480.1 993258 994001 R conserved hypothetical protein (AAS20096.1| hypothetical protein [Arthrobacter aurescens]; ZP_00293399.1| hypothetical protein Tfus02000754 [Thermobifida fusca]).; hypothetical protein complement(993258..994001) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173025 YP_001221612.1 CDS cysB NC_009480.1 994171 995535 D putative cystathionine beta-synthase (Serine sulfhydrase) (BAB96806.1| probable cystathionine beta-synthase [Rhodococcus erythropolis]; ZP_00227382.1| COG0031: Cysteine synthase [Kineococcus radiotolerans SRS30216]). pfam00291, PALP, Pyridoxal-phosphate dependent enzyme. COG0517, FOG: CBS domain [General function prediction only], pfam00571, CBS, CBS domain. CBS domains are small intracellular modules of unknown function.; High confidence in function and specificity; putative cystathionine beta-synthase 994171..995535 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173068 YP_001221613.1 CDS metB NC_009480.1 995583 996755 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 995583..996755 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174798 YP_001221614.1 CDS rnhA NC_009480.1 996801 997559 R putative Ribonuclease H (YP_062422.1| ribonuclease H [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056416.1| ribonuclease H [Propionibacterium acnes KPA171202]). pfam00075, RnaseH, RNase H. RNase H digests the RNA strand of an RNA/DNA hybrid. pfam01402, HTH_4, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerisation and not DNA binding as might have been expected.; High confidence in function and specificity; ribonuclease H complement(996801..997559) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174739 YP_001221615.1 CDS CMM_0875 NC_009480.1 997737 998759 D putative transcriptional regulator, LacI-family (NP_630441.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00198171.1| hypothetical protein Krad024574 [Kineococcus radiotolerans SRS30216]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; LacI family transcriptional regulator 997737..998759 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173061 YP_001221616.1 CDS araB NC_009480.1 998939 1000642 D catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 998939..1000642 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173055 YP_001221617.1 CDS araD NC_009480.1 1000639 1001349 D catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate; L-ribulose-5-phosphate 4-epimerase 1000639..1001349 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175021 YP_001221618.1 CDS araA NC_009480.1 1001346 1002863 D catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 1001346..1002863 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173360 YP_001221619.1 CDS CMM_0879 NC_009480.1 1002940 1004070 D putative sugar ABC transporter, substrate-binding protein (ZP_00198172.2| COG4213: ABC-type xylose transport system, periplasmic component [Kineococcus radiotolerans SRS30216]; NP_769848.1| ABC transporter sugar-binding protein [Bradyrhizobium japonicum USDA 110]). pfam00532,Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators.; Specificity unclear; putative sugar ABC transporter substrate-binding protein 1002940..1004070 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174052 YP_001221620.1 CDS CMM_0880 NC_009480.1 1004248 1005777 D putative sugar ABC transporter, ATPase component (ZP_00225839.1| COG1129: ABC-type sugar transport system,ATPase component [Kineococcus radiotolerans SRS30216]; NP_826945.1| putative sugar ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]). pfam00005,ABC_tran, ABC transporter (twice, two fused ATPases).; Specificity unclear; putative sugar ABC transporter ATPase 1004248..1005777 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173119 YP_001221621.1 CDS CMM_0881 NC_009480.1 1005783 1006970 D putative sugar ABC transporter, permease component (AAD45714.1| L-arabinose membrane permease [Geobacillus stearothermophilus]; NP_626652.1| putative sugar transport permease [Streptomyces coelicolor A3(2)]). pfam02653, BPD_transp_2, Branched-chain amino acid transport system / permease component (twice, two fused permeases).; Specificity unclear; putative sugar ABC transporter permease 1005783..1006970 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173100 YP_001221622.1 CDS xylA NC_009480.1 1007319 1008512 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(1007319..1008512) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173138 YP_001221623.1 CDS bglJ NC_009480.1 1008717 1010219 D putative beta-glucosidase (ZP_00188825.3| COG2723: Beta-glucosidase/ 6-phospho-beta-glucosidase/beta-galactosidase [Kineococcus radiotolerans SRS30216]; S45675 beta-glucosidase (EC 3.2.1.21) - Streptomyces sp. (strain QM-B814)). pfam00232, Glyco_hydro_1, Glycosyl hydrolase family 1.; Specificity unclear; beta-glucosidase 1008717..1010219 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174248 YP_001221624.1 CDS CMM_0884 NC_009480.1 1010216 1010782 D putative acetyltransferase (ZP_00227685.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Kineococcus radiotolerans SRS30216]; NP_389071.1|; Function unclear; putative acetyltransferase 1010216..1010782 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175482 YP_001221625.1 CDS CMM_0885 NC_009480.1 1010813 1011250 R putative transcriptional regulator, MarR family (ZP_00227991.1| COG1846: Transcriptional regulators [Kineococcus radiotolerans SRS30216]; NP_790665.1| transcriptional regulator, MarR family [Pseudomonas syringae pv. tomato str. DC3000]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator complement(1010813..1011250) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173155 YP_001221626.1 CDS CMM_0886 NC_009480.1 1011375 1011710 R hypothetical protein complement(1011375..1011710) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173174 YP_001221627.1 CDS CMM_0887 NC_009480.1 1011839 1012795 R putative transcriptional regulator, LysR family (NP_628924.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00292125.1| COG0583: Transcriptional regulator [Thermobifida fusca]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate, LysR substrate binding domain.; Specificity unclear; hypothetical protein complement(1011839..1012795) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174771 YP_001221628.1 CDS CMM_0888 NC_009480.1 1012877 1013932 D putative selenocysteine lyase (ZP_00057151.1| COG0520: Selenocysteine lyase [Thermobifida fusca]; NP_626135.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam00266, Aminotran_5,Aminotransferase class-V.; Family membership; hypothetical protein 1012877..1013932 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173201 YP_001221629.1 CDS CMM_0889 NC_009480.1 1014064 1015299 D putative MFS-type efflux transporter (ZP_00198278.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_827094.1| putative bicyclomycin resistance protein [Streptomyces avermitilis MA-4680]). pfam00083,Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS-type efflux transporter 1014064..1015299 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173190 YP_001221630.1 CDS CMM_0890 NC_009480.1 1015340 1016434 D putative membrane protein (NP_822458.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00056876.1| hypothetical protein [Thermobifida fusca]).; Function unclear; hypothetical protein 1015340..1016434 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173263 YP_001221631.1 CDS strB NC_009480.1 1016431 1017318 R putative streptomycin-kinase(AAN18030.1| putative streptomycin-3-kinase [Pseudomonas aurantiaca]; NP_250549.1| streptomycin 3''-phosphotransferase [Pseudomonas aeruginosa PA01]). pfam04655, APH_6_hur,Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.; Specificity unclear; putative streptomycin phosphotransferase complement(1016431..1017318) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173219 YP_001221632.1 CDS CMM_0892 NC_009480.1 1017315 1017965 R hypothetical protein complement(1017315..1017965) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175640 YP_001221633.1 CDS CMM_0893 NC_009480.1 1018383 1021241 R putative transcriptional regulator, LuxR family (ZP_00228816.1| COG2771: DNA-binding HTH domain-containing proteins [Kineococcus radiotolerans SRS30216]; NP_733725.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_335345.1| transcriptional regulator, LuxR family [Mycobacterium tuberculosis CDC1551]). pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; LuxR family transcriptional regulator complement(1018383..1021241) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173166 YP_001221634.1 CDS CMM_0894 NC_009480.1 1021575 1022228 R putative nucleoside-diphosphate-sugar epimerase (ZP_00058107.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Thermobifida fusca]; NP_826075.1| hypothetical protein SAV4898 [Streptomyces avermitilis MA-4680]).; Function unclear; putative nucleoside-diphosphate-sugar epimerase complement(1021575..1022228) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173233 YP_001221635.1 CDS ptaA NC_009480.1 1022461 1024578 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 1022461..1024578 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175704 YP_001221636.1 CDS ackA NC_009480.1 1024644 1025834 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1024644..1025834 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174998 YP_001221637.1 CDS CMM_0897 NC_009480.1 1026122 1031185 D putative cell surface protein (putative adhesin,putative hemagglutinin/hemolysin-related protein) (NP_879893.1| putative outer membrane ligand binding protein [Bordetella pertussis Tohama I]).; Conserved hypothetical protein; hypothetical protein 1026122..1031185 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175462 YP_001221638.1 CDS CMM_0898 NC_009480.1 1031353 1032204 D hypothetical protein 1031353..1032204 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173278 YP_001221639.1 CDS CMM_0899 NC_009480.1 1032201 1033412 D conserved membrane protein (NP_825339.1| hypothetical protein SAV4162 [Streptomyces avermitilis MA-4680]; NP_864673.1| conserved hypothetical protein [Pirellula sp. 1]).; hypothetical protein 1032201..1033412 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173316 YP_001221640.1 CDS CMM_0900 NC_009480.1 1033458 1035938 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1033458..1035938 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173308 YP_001221641.1 CDS recR NC_009480.1 1035945 1036544 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1035945..1036544 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173333 YP_001221642.1 CDS lysC NC_009480.1 1036654 1037919 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1036654..1037919 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173179 YP_001221643.1 CDS asdA NC_009480.1 1037969 1039066 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1037969..1039066 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175880 YP_001221644.1 CDS mqoA NC_009480.1 1039154 1040632 D malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 1039154..1040632 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174621 YP_001221645.1 CDS CMM_0905 NC_009480.1 1040702 1041886 D conserved hypothetical protein (YP_061469.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; CAB01265.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_630564.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam04055, Radical_SAM, Radical SAM superfamily.; High confidence in function and specificity; hypothetical protein 1040702..1041886 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174140 YP_001221646.1 CDS CMM_0906 NC_009480.1 1041957 1042655 D putative two-component system, response regulator (NP_737890.1| putative transcription regulator [Corynebacterium efficiens YS-314]; ZP_00033625.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Burkholderia fungorum]). pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system, response regulator 1041957..1042655 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173351 YP_001221647.1 CDS tdkA NC_009480.1 1042656 1043330 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1042656..1043330 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173379 YP_001221648.1 CDS CMM_0908 NC_009480.1 1043686 1045080 D putative tyrosine-protein kinase (NP_599595.1| putative ATPase involved in chromosome partitioning [Corynebacterium glutamicum ATCC 13032]; ZP_00190418.2| COG0489: ATPases involved in chromosome partitioning [Kineococcus radiotolerans SRS30216]). , N-terminal: COG3944, Capsular polysaccharide biosynthesis protein,pfam02706, Wzz, Chain length determinant protein. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This region is also found as part of bacterial tyrosine kinases. , C-terminal: COG0489, Mrp,ATPases involved in chromosome partitioning; Function unclear; putative tyrosine-protein kinase 1043686..1045080 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175978 YP_001221649.1 CDS CMM_0909 NC_009480.1 1045419 1046369 D hypothetical protein (BAB97739.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032]).; Function unclear; hypothetical protein 1045419..1046369 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173404 YP_001221650.1 CDS CMM_0910 NC_009480.1 1046366 1048186 D hypothetical protein (ZP_00120927.1| COG1463: ABC-type transport system involved in resistance to organic solvents, periplasmic component [Bifidobacterium longum DJO10A]; ZP_00120551.1| COG0840: Methyl-accepting chemotaxis protein [Bifidobacterium longum DJO10A]; ZP_00199275.1| hypothetical protein Krad06001109 [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein 1046366..1048186 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173386 YP_001221651.1 CDS CMM_0911 NC_009480.1 1048274 1048858 D hypothetical protein 1048274..1048858 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173439 YP_001221652.1 CDS CMM_0912 NC_009480.1 1049131 1049721 D hypothetical protein 1049131..1049721 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173420 YP_001221653.1 CDS CMM_0913 NC_009480.1 1049761 1050288 R conserved membrane protein, putative resistance protein (NP_347289.1| Uncharacterized conserved membrane protein, ; NP_832420.1| Teicoplanin resistance protein vanZ [Bacillus cereus ATCC 14579]). pfam04892, VanZ, VanZ like family.; Function unclear; hypothetical protein complement(1049761..1050288) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173462 YP_001221654.1 CDS CMM_0914 NC_009480.1 1050375 1051388 D putative flavin-dependent oxidoreductase/monooxygenase (NP_826413.1| putative LuxAB-like protein (oxygenase) [Streptomyces avermitilis MA-4680]; CAF25096.1| putative alkanalmonooxygenase [Yersinia enterocolitica]) pfam00296, Bac_luciferase,Luciferase-like monooxygenase. InterPro: Bacterial luciferase.; Function unclear; putative flavin-dependent oxidoreductase/monooxygenase 1050375..1051388 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173432 YP_001221655.1 CDS pbpC NC_009480.1 1051481 1053715 D putative penicillin-binding protein (YP_061622.1| penicillin-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789643.1| putative penicillin-binding protein/transpeptidase [Tropheryma whipplei TW08/27]; ZP_00120566.1| hypothetical protein Blon020421 [Bifidobacterium longum DJO10A]). Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. pfam00912, Transgly, Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyses the polymerisation of murein glycan chains. pfam00905, Transpeptidase, Penicillin binding protein transpeptidase domain. The active site serine is conserved in all members of this family.; Specificity unclear; putative penicillin-binding protein 1051481..1053715 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173493 YP_001221656.1 CDS CMM_0916 NC_009480.1 1053861 1055141 D putative acyltransferase (ZP_00226320.1| COG1835: Predicted acyltransferases [Kineococcus radiotolerans SRS30216]; NP_298068.1| O-antigen acetylase [Xylella fastidiosa 9a5c]; ZP_00058493.1| COG1835: Predicted acyltransferases [Thermobifida fusca]). pfam01757,Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes.; Specificity unclear; putative acyltransferase 1053861..1055141 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175496 YP_001221657.1 CDS CMM_0917 NC_009480.1 1055138 1055590 D hypothetical membrane protein; Hypothetical protein; hypothetical protein 1055138..1055590 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173450 YP_001221658.1 CDS CMM_0918 NC_009480.1 1055835 1056779 R putative phosphohydrolase (YP_061478.1| phosphohydrolase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789644.1| putative secreted protein [Tropheryma whipplei TW08/27]). InterPro: Serine/threonine specific protein phosphatase. pfam00149, Metallophos,Calcineurin-like phosphoesterase. This family includes a diverse range of phosphoesterases, including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD or yeast MRE11.; Function unclear; putative phosphohydrolase complement(1055835..1056779) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173927 YP_001221659.1 CDS pbpD NC_009480.1 1056779 1059316 R putative membrane carboxypeptidase (penicillin-binding protein) (YP_061622.1| penicillin-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789643.1| putative penicillin-binding protein/transpeptidase [Tropheryma whipplei TW08/27]). InterPro: Penicillin binding protein transpeptidase domain. pfam00912,Transgly, Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyses the polymerisation of murein glycan chains. pfam00905, Transpeptidase, Penicillin binding protein transpeptidase domain. The active site serine is conserved in all members of this family. pfam03793, PASTA, PASTA domain. This domain is found at the C termini of several Penicillin-binding proteins and bacterial serine/threonine kinases. It binds the beta-lactam stem, which implicates it in sensing D-alanyl-D-alanine - the PBP transpeptidase substrate.; Specificity unclear; putative penicillin-binding protein complement(1056779..1059316) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173508 YP_001221660.1 CDS CMM_0920 NC_009480.1 1059422 1059604 D conserved hypothetical protein (NP_787831.1| unknown [Tropheryma whipplei str. Twist]; NP_938688.1| Conserved hypothetical protein [Corynebacterium diphtheriae]).; hypothetical protein 1059422..1059604 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175512 YP_001221661.1 CDS CMM_0921 NC_009480.1 1059604 1060068 D putative endoribonuclease, putative translation initiation inhibitor (NP_627772.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_959330.1| hypothetical protein MAP0396 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam01042, Ribonuc_L-PSP,Endoribonuclease L-PSP. Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis. TIGR00004: endoribonuclease L-PSP puta; Function unclear; putative endoribonuclease translation initiation inhibitor 1059604..1060068 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173557 YP_001221662.1 CDS acsA1 NC_009480.1 1060150 1062189 R putative acetyl-coenzyme A synthetase (Acetate-CoA ligase) (ZP_00227761.1| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Kineococcus radiotolerans SRS30216]; ZP_00058154.1| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Thermobifida fusca]). pfam00501, AMP-binding, AMP-binding enzyme.; Specificity unclear; acetyl-coenzyme A synthetase complement(1060150..1062189) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173569 YP_001221663.1 CDS CMM_0923 NC_009480.1 1062551 1063795 D putative ATPase (NP_787829.1| putative type II/type IV pathway secretion protein [Tropheryma whipplei str. Twist]; NP_599554.2| predicted ATPase involved in pili and flagella biosynthesis [Corynebacterium glutamicum ATCC 13032]). pfam00437, GSPII_E, Type II/IV secretion system protein. This family contains both type II and type IV pathway secretion proteins from bacteria. also VirB11 (COG0630)- similarity; Family membership; hypothetical protein 1062551..1063795 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173158 YP_001221664.1 CDS CMM_0924 NC_009480.1 1063792 1064817 D conserved membrane protein (NP_789640.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; NP_798789.1| putative tight adherence TadC-related transmembrane protein [Vibrio parahaemolyticus RIMD 2210633]). weak similarity to: pfam00482, GSPII_F,Bacterial type II secretion system protein F domain.; Family membership; hypothetical protein 1063792..1064817 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173578 YP_001221665.1 CDS CMM_0925 NC_009480.1 1064943 1065368 D hypothetical protein (AAN24334.1| hypothetical protein BL0505 [Bifidobacterium longum NCC2705]).; hypothetical protein 1064943..1065368 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173601 YP_001221666.1 CDS CMM_0925A NC_009480.1 1065365 1065766 D hypothetical protein (AAT88406.1| hypothetical protein Lxx04030 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789638.1| hypothetical protein TW717 [Tropheryma whipplei TW08/27]); hypothetical protein 1065365..1065766 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173641 YP_001221667.1 CDS CMM_0926 NC_009480.1 1065756 1066115 D hypothetical protein (AAO44794.1| unknown [Tropheryma whipplei str. Twist]).; hypothetical protein 1065756..1066115 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173622 YP_001221668.1 CDS topA NC_009480.1 1066457 1069411 D DNA topoisomerase I (ZP_00227140.1| COG0550: Topoisomerase IA [Kineococcus radiotolerans SRS30216]; NP_959359.1| TopA [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam01751, Toprim, Toprim domain. This is a conserved region from DNA primase. pfam01131, Topoisom_bac, DNA topoisomerase.; High confidence in function and specificity; DNA topoisomerase I 1066457..1069411 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173699 YP_001221669.1 CDS tmkA NC_009480.1 1069408 1070043 D Thymidylate kinase (dTMP kinase) (Q8G6Z6|KTHY_BIFLO Thymidylate kinase (dTMP kinase); Q9RY40|KTHY_DEIRA Thymidylate kinase (dTMP kinase)). pfam02223,Thymidylate_kin, Thymidylate kinase. DTMP_kinase: thymidylate kinase; High confidence in function and specificity; hypothetical protein 1069408..1070043 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173708 YP_001221670.1 CDS holB NC_009480.1 1070040 1071284 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1070040..1071284 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175639 YP_001221671.1 CDS CMM_0930 NC_009480.1 1071281 1072858 D putative proteinase (ZP_00227136.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Kineococcus radiotolerans SRS30216]; NP_825801.1| putative proteinase [Streptomyces avermitilis MA-4680]). pfam00561, Abhydrolase_1,alpha/beta hydrolase fold (only weak similarity).; Conserved hypothetical protein; hypothetical protein 1071281..1072858 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174946 YP_001221672.1 CDS pbpE NC_009480.1 1073336 1074694 D D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 4 precursor (NP_601895.1| D-alanyl-D-alanine carboxypeptidase [Corynebacterium glutamicum ATCC 13032]; NP_218144.1| hypothetical protein Rv3627c [Mycobacterium tuberculosis H37Rv]). Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction. PBP4: D-alanyl-D-alanine carboxypeptid pfam02113, Peptidase_S13, D-Ala-D-Ala carboxypeptidase 3 (S13) family.; Function unclear; D-alanyl-D-alanine carboxypeptidase 1073336..1074694 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173904 YP_001221673.1 CDS pncA NC_009480.1 1074759 1075349 D putative pyrazinamidase/nicotinamidase (CAA17257.1| PYRAZINAMIDASE/NICOTINAMIDAS PNCA (PZase) [Mycobacterium tuberculosis H37Rv]; NP_787820.1| pyrazinamidase; nicotinamidase [Tropheryma whipplei str. Twist])., ,pfam00857, Isochorismatase, Isochorismatase family. This family are hydrolase enzymes.; Specificity unclear; putative pyrazinamidase / nicotinamidase 1074759..1075349 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175529 YP_001221674.1 CDS gabD NC_009480.1 1075427 1076902 D putative succinate-semialdehyde dehydrogenase [NADP+] (ZP_00293214.1| COG1012: NAD-dependent aldehyde dehydrogenases [Thermobifida fusca]; YP_054797.1| aldehyde dehydrogenase [Propionibacterium acnes KPA171202]). pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor.; High confidence in function and specificity; putative succinate-semialdehyde dehydrogenase 1075427..1076902 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173378 YP_001221675.1 CDS CMM_0934 NC_009480.1 1076902 1077702 D putative tRNA/rRNA methyltransferase (YP_062139.1| rRNA methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056231.1| rRNA methylase family protein [Propionibacterium acnes KPA171202]). pfam00588,SpoU_methylase, SpoU rRNA Methylase family. This family of proteins probably use S-AdoMet. InterPro: tRNA/rRNA methyltransferase (SpoU).; Function unclear; putative tRNA/rRNA methyltransferase 1076902..1077702 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174506 YP_001221676.1 CDS CMM_0935 NC_009480.1 1077769 1078116 D hypothetical protein (NP_895470.1| conserved hypothetical protein [Prochlorococcus marinus str. MIT 9313]; NP_898274.1| conserved hypothetical [Synechococcus sp. WH 8102]).; hypothetical protein 1077769..1078116 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173766 YP_001221677.1 CDS CMM_0936 NC_009480.1 1078250 1078618 D hypothetical protein (NP_895470.1| conserved hypothetical protein [Prochlorococcus marinus str. MIT 9313]; NP_898274.1| conserved hypothetical [Synechococcus sp. WH 8102]).; hypothetical protein 1078250..1078618 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173685 YP_001221678.1 CDS CMM_0937 NC_009480.1 1078702 1080633 R putative multidrug export ABC transporter, fused permease and ATP-binding protein (YP_061527.1| ABC transporter, NBP/MSD fusion protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627447.1| putative ABC transporter [Streptomyces coelicolor A3(2)]). pfam00664, ABC_membrane,ABC transporter transmembrane region. pfam00005, ABC_tran,ABC transporter.; Function unclear; putative multidrug export ABC transporter fused permease and ATP-binding protein complement(1078702..1080633) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173774 YP_001221679.1 CDS CMM_0938 NC_009480.1 1080838 1081764 D putative multidrug export ABC transporter, ATP-binding protein (ZP_00199970.1| COG1131: ABC-type multidrug transport system, ATPase component [Rubrobacter xylanophilus DSM 9941]; CAH04372.1| NodI membrane transport protein [Sinorhizobium sp. BR816]). pfam00005,ABC_tran, ABC transporter.; Specificity unclear; putative multidrug export ABC transporter ATP-binding protein 1080838..1081764 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173744 YP_001221680.1 CDS CMM_0939 NC_009480.1 1081761 1082594 D putative multidrug export ABC transporter, permease component (NP_435717.1| NodJ membrane transport protein [Sinorhizobium meliloti 1021]; ZP_00271835.1| COG0842: ABC-type multidrug transport system, permease component [Ralstonia metallidurans CH34]). pfam01061, ABC2_membrane,ABC-2 type transporter.; Function unclear; putative multidrug export ABC transporterpermease 1081761..1082594 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173831 YP_001221681.1 CDS CMM_0940 NC_009480.1 1082591 1083433 D putative multidrug export ABC transporter, permease component (ZP_00329441.1| COG0842: ABC-type multidrug transport system, permease component [Moorella thermoacetica ATCC 39073]; ZP_00291807.1| COG0842: ABC-type multidrug transport system, permease component [Thermobifida fusca]). pfam01061, ABC2_membrane, ABC-2 type transporter.; Specificity unclear; putative multidrug export ABC transporterpermease 1082591..1083433 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173803 YP_001221682.1 CDS CMM_0941 NC_009480.1 1083396 1084745 R putative MFS permease (NP_530800.1| MFS permease [Agrobacterium tumefaciens str. C58]; ZP_00195331.1| COG0477: Permeases of the major facilitator superfamily [Mesorhizobium sp. BNC1]). pfam05977, DUF894, Bacterial protein of unknown function (DUF894). This family consists of several bacterial proteins, many of which are annotated as putative transmembrane transport proteins.; Specificity unclear; MFS family transporter complement(1083396..1084745) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173870 YP_001221683.1 CDS CMM_0942 NC_009480.1 1084888 1085718 D putative ribokinase (ZP_00019960.1| hypothetical protein [Chloroflexus aurantiacus]; NP_781564.1| ribokinase [Clostridium tetani E88]). pfam00294, PfkB,pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases.; Specificity unclear; hypothetical protein 1084888..1085718 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173893 YP_001221684.1 CDS CMM_0943 NC_009480.1 1085724 1086191 D hypothetical protein 1085724..1086191 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173938 YP_001221685.1 CDS CMM_0944 NC_009480.1 1086418 1087686 D putative sugar ABC transporter, substrate-binding protein (NP_637562.1| ABC transporter sugar binding protein [Xanthomonas campestris pv. campestris str. ATCC 33913]; ZP_00233263.1| ABC transporter, substrate-binding protein [Listeria monocytogenes str. 1/2a F6854]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter substrate-binding protein 1086418..1087686 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173962 YP_001221686.1 CDS CMM_0945 NC_009480.1 1087690 1088631 D putative sugar ABC transporter, permease component (NP_779660.1| ABC transporter sugar permease [Xylella fastidiosa Temecula1]; AAM24057.1| ABC-type sugar transport systems, permease components [Thermoanaerobacter tengcongensis MB4]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 1087690..1088631 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174005 YP_001221687.1 CDS CMM_0946 NC_009480.1 1088643 1089554 D putative sugar ABC transporter, permease component (NP_471178.1| ; NP_694344.1| sugar binding-protein dependent transporter system permease [Oceanobacillus iheyensis HTE831]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 1088643..1089554 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173976 YP_001221688.1 CDS CMM_0947 NC_009480.1 1089587 1091449 D putative beta-glycosidase (EAA49874.1| hypothetical protein MG10038.4 [Magnaporthe grisea 70-15]; CAD47965.1| putative beta-glucosidase [Arthrobacter nicotinovorans]; ZP_00214214.1| COG1472: Beta-glucosidase-related glycosidases [Burkholderia cepacia R18194]). pfam00933,Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915, Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.sim; Specificity unclear; putative beta-glycosidase 1089587..1091449 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174078 YP_001221689.1 CDS CMM_0948 NC_009480.1 1091558 1092697 D puative transcriptional regulator, LacI family (Q45831|REGA_CLOSA HTH-type transcriptional regulator regA; ZP_00186316.1| COG1609: Transcriptional regulators [Rubrobacter xylanophilus DSM 9941]). pfam00356, LacI,Bacterial regulatory proteins, lacI family. pfam00532,Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family. InterPro: Periplasmic binding proteins and sugar binding domain LacI family.; Specificity unclear; LacI family transcriptional regulator 1091558..1092697 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174028 YP_001221690.1 CDS CMM_0949 NC_009480.1 1092708 1092917 R Hypothetical protein; hypothetical protein complement(1092708..1092917) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174135 YP_001221691.1 CDS CMM_0950 NC_009480.1 1092917 1093471 R conserved hypothetical protein (ZP_00141347.1| COG2258: Uncharacterized protein conserved in bacteria [Pseudomonas aeruginosa UCBPP-PA14]; ZP_00189460.2| COG2258: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). pfam03473, MOSC,MOSC domain. The MOSC (MOCO sulfurase C-terminal) domain is a superfamily of beta-strand-rich domains identified in the molybdenum cofactor sulfurase and several other proteins from both prokaryotes and eukaryotes.; Function unclear; hypothetical protein complement(1092917..1093471) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174041 YP_001221692.1 CDS CMM_0951 NC_009480.1 1093591 1094295 D Hypothetical protein; hypothetical protein 1093591..1094295 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174171 YP_001221693.1 CDS CMM_0952 NC_009480.1 1094342 1095748 R putative MFS permease (NP_629604.1| transmembrane transport protein [Streptomyces coelicolor A3(2)]; NP_386279.1| PUTATIVE TRANSPORT TRANSMEMBRANE PROTEIN [Sinorhizobium meliloti]). pfam00083, Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters.; Specificity unclear; putative MFS permease complement(1094342..1095748) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174098 YP_001221694.1 CDS CMM_0953 NC_009480.1 1095854 1097269 R putative MFS permease (NP_629604.1| transmembrane transport protein [Streptomyces coelicolor A3(2)]; NP_695723.1| transmembrane transport protein possibly for shikimate [Bifidobacterium longum NCC2705]). pfam00083,Sugar_tr, Sugar (and other) transporter. 2A0106: citrate-proton symport; Specificity unclear; putative MFS permease complement(1095854..1097269) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174243 YP_001221695.1 CDS CMM_0954 NC_009480.1 1097486 1097782 D hypothetical protein 1097486..1097782 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174206 YP_001221696.1 CDS CMM_0955 NC_009480.1 1097779 1099572 R putative peptide ABC transporter, permease compound (NP_630721.1| putative transport system permease protein [Streptomyces coelicolor A3(2)]; YP_049650.1| putative transport system membrane protein [Erwinia carotovora subsp. atroseptica SCRI1043]). two fused permease domains (COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components and COG1173, DppC,ABC-type dipeptide/oligopeptide/nickel transport systems,permease components).; Specificity unclear; putative peptide ABC transporter permease compound complement(1097779..1099572) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174285 YP_001221697.1 CDS CMM_0956 NC_009480.1 1099572 1101113 R putative peptide ABC transporter, binding protein (YP_049651.1| putative ABC transporter substrate-binding protein [Erwinia carotovora subsp. atroseptica SCRI1043]; NP_630720.1| putative solute-binding lipoprotein [Streptomyces coelicolor A3(2)]). pfam00496, SBP_bac_5,Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative peptide ABC transporter substrate-binding protein complement(1099572..1101113) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174300 YP_001221698.1 CDS CMM_0957 NC_009480.1 1101103 1102527 R putative MFS permease (YP_049652.1| putative transport system membrane protein [Erwinia carotovora subsp. atroseptica SCRI1043]; ZP_00226985.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam00083,Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters 2A0115: benzoate transport; Specificity unclear; putative MFS permease complement(1101103..1102527) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174357 YP_001221699.1 CDS CMM_0958 NC_009480.1 1102524 1103351 R putative peptide ABC transporter, ATP-binding protein (NP_943428.1| ABC transporter, ATP-binding protin [Klebsiella pneumoniae]; AAP21664.1| Shy17 [Streptomyces hygroscopicus subsp. yingchengensis]). pfam00005,ABC_tran, ABC transporter.; Specificity unclear; putative peptide ABC transporter ATP-binding protein complement(1102524..1103351) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174403 YP_001221700.1 CDS CMM_0959 NC_009480.1 1103348 1104208 R putative peptide ABC transporter, ATP-binding protein (NP_244513.1| oligopeptide ABC transporter (ATP-binding protein) [Bacillus halodurans]; NP_693374.1| oligopeptide ABC transporter ATP-binding protein [Oceanobacillus iheyensis HTE831]). pfam00005, ABC_tran,ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative peptide ABC transporter ATP-binding protein complement(1103348..1104208) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174459 YP_001221701.1 CDS ribH NC_009480.1 1104310 1104792 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(1104310..1104792) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174431 YP_001221702.1 CDS ribAB NC_009480.1 1104789 1106123 R Riboflavin biosynthesis protein ribA [Includes: GTP cyclohydrolase II (EC 3.5.4.25) and 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase)] (YP_061534.1| GTP cyclohydrolase II; 3,4-dihydroxy- 2-butanone-4-phosphate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_293879.1| GTP cyclohydrolase II/3,4-dihydroxy- 2-butanone-4-phosphate synthase [Deinococcus radiodurans R1]). contains two domains: N-terminal,pfam00926, DHBP_synthase, 3,4-dihydroxy-2-butanone 4-phosphate synthase. C-terminal, COG0807, RibA, GTP cyclohydrolase II [Coenzyme metabolism], pfam00925,GTP_cyclohydro2, GTP cyclohydrolase II.; High confidence in function and specificity; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(1104789..1106123) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174053 YP_001221703.1 CDS ribC NC_009480.1 1106120 1106776 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1106120..1106776) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174207 YP_001221704.1 CDS ribD NC_009480.1 1106776 1107846 R Riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) (Riboflavin-specific deaminase) and 5-amino-6-(5-phosphoribosylamino) uracil reductase (EC 1.1.1.193) (HTP reductase)] (YP_061536.1| riboflavin-specific deaminase; riboflavin-specific reductase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_855096.1| PROBABLE BIFUNCTIONAL riboflavin biosynthesis protein RIBG : Diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin- specific deaminase) + 5-amino-6-(5-phosphoribosylamino) uracil reductase (HTP reductase) [Mycobacterium bovis AF2122/97]). contains two domains: N-terminally, COG0117, RibD, Pyrimidine deaminase [Coenzyme metabolism]; pfam00383, dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region. C-terminally, COG1985, RibD, Pyrimidine reductase,riboflavin biosynthesis [Coenzyme metabolism]; pfam01872,RibD_C, RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis.; High confidence in function and specificity; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase complement(1106776..1107846) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174955 YP_001221705.1 CDS CMM_0964 NC_009480.1 1108127 1108891 R putative hydrolase (NP_629683.1| putative hydrolase [Streptomyces coelicolor A3(2)]; ZP_00191679.2| COG1011: Predicted hydrolase (HAD superfamily) [Kineococcus radiotolerans SRS30216]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This family are structurally different from the alpha/ beta hydrolase family (pfam00561). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.; Function unclear; putative hydrolase complement(1108127..1108891) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175554 YP_001221706.1 CDS trpS NC_009480.1 1108888 1109901 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(1108888..1109901) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174597 YP_001221707.1 CDS xthA NC_009480.1 1109984 1110829 R putative exonuclease III (NP_787813.1| putative exodeoxyribonuclease [Tropheryma whipplei str. Twist]; ZP_00198614.2| COG0708: Exonuclease III [Kineococcus radiotolerans SRS30216]). pfam03372, Exo_endo_phos,Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling.; High confidence in function and specificity; putative exonuclease III complement(1109984..1110829) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173922 YP_001221708.1 CDS CMM_0967 NC_009480.1 1110840 1111949 R conserved membrane protein, putative ribonuclease (ZP_00121873.1| COG1295: Predicted membrane protein [Bifidobacterium longum DJO10A]; NP_599910.1| multiple transmembrane domain containing protein [Corynebacterium glutamicum ATCC 13032]). pfam03631, Ribonuclease_BN,Ribonuclease BN-like family. This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation.; Function unclear; putative ribonuclease complement(1110840..1111949) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174361 YP_001221709.1 CDS ptsA NC_009480.1 1112074 1113729 D Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, EI component) (NP_828150.1| putative phosphoenolpyruvate- protein phosphotransferase [Streptomyces avermitilis MA-4680]; ZP_00293042.1| COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Thermobifida fusca]). pfam05524,PEP-utilisers_N, PEP-utilising enzyme, N-terminal. pfam00391, PEP-utilizers, PEP-utilising enzyme, mobile domain. pfam02896, PEP-utilizers_C, PEP-utilising enzyme,TIM barrel domain. InterPro: PEP-utilizing enzyme.; Specificity unclear; phosphoenolpyruvate--protein phosphatase 1112074..1113729 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174481 YP_001221710.1 CDS sdhB NC_009480.1 1113818 1114579 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit complement(1113818..1114579) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174833 YP_001221711.1 CDS sdhA NC_009480.1 1114637 1116460 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit complement(1114637..1116460) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174839 YP_001221712.1 CDS sdhD NC_009480.1 1116493 1116957 R succinate dehydrogenase, hydrophobic membrane subunit (YP_061549.1| succinate dehydrogenase, membrane subunit [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225992.1| COG2142: Succinate dehydrogenase,hydrophobic anchor subunit [Kineococcus radiotolerans SRS30216]). pfam01127, Sdh_cyt, Succinate dehydrogenase cytochrome b subunit.; High confidence in function and specificity; putative succinate dehydrogenase, hydrophobic membrane subunit complement(1116493..1116957) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174643 YP_001221713.1 CDS sdhC NC_009480.1 1116960 1117394 R succinate dehydrogenase, cytochrome b subunit (NP_629013.1| putative succinate dehydrogenase membrane subunit [Streptomyces coelicolor A3(2)]; ZP_00225993.1| COG2009: Succinate dehydrogenase/fumarate reductase,cytochrome b subunit [Kineococcus radiotolerans SRS30216]). MONO-HEME CYTOCHROME OF THE SUCCINATE DEHYDROGENASE COMPLEX. pfam01127, Sdh_cyt, Succinate dehydrogenase cytochrome b subunit.; High confidence in function and specificity; succinate dehydrogenase, cytochrome b subunit complement(1116960..1117394) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174191 YP_001221714.1 CDS CMM_0973 NC_009480.1 1117535 1118728 R putative mannosyl transferase (CAB08968.1| MANNOSYLTRANSFERASE PIMB [Mycobacterium tuberculosis H37Rv]; NP_737090.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). InterPro: Glycosyl transferases group 1. pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Specificity unclear; putative mannosyl transferase complement(1117535..1118728) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175055 YP_001221715.1 CDS manC NC_009480.1 1118828 1119949 D Mannose-1-phosphate guanylyltransferase (NP_787484.1| Mannose-1-phosphate guanylyltransferase [Tropheryma whipplei str. Twist]; ZP_00225994.1| COG0836: Mannose-1-phosphate guanylyltransferase [Kineococcus radiotolerans SRS30216]). INVOLVED IN GDP-MANNOSE BIOSYNTHESIS WHICH SERVES AS THE ACTIVATED SUGAR NUCLEOTIDE PRECURSOR FOR MANNOSE RESIDUES IN CELL SURFACE POLYSACCHARIDES. InterPro: ADP-glucose pyrophosphorylase. pfam00483, NTP_transferase, Nucleotidyl transferase. This family includes a wide range of enzymes which transfer nucleotides onto phosphosugars.; High confidence in function and specificity; hypothetical protein 1118828..1119949 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174534 YP_001221716.1 CDS CMM_0975 NC_009480.1 1120024 1121097 D putative ABC transporter, substrate-binding protein (ZP_00225996.1| COG1744: Uncharacterized ABC-type transport system, periplasmic component/ surface lipoprotein [Kineococcus radiotolerans SRS30216]; NP_622136.1| Surface lipoprotein [Thermoanaerobacter tengcongensis]). pfam02608, Bmp, Basic membrane protein. This is a family of basic membrane lipoproteins form Borrelia and various putative lipoproteins form other bacteria.; Function unclear; putative ABC transporter substrate-binding protein 1120024..1121097 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175172 YP_001221717.1 CDS CMM_0976 NC_009480.1 1121248 1122342 D putative ABC transporter, substrate-binding protein (ZP_00225996.1| COG1744: Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [Kineococcus radiotolerans SRS30216]; NP_622136.1| Surface lipoprotein [Thermoanaerobacter tengcongensis]). pfam02608, Bmp, Basic membrane protein. This is a family of basic membrane lipoproteins form Borrelia and various putative lipoproteins form other bacteria. InterPro: Basic membrane lipoprotein.; Function unclear; putative ABC transporter substrate-binding protein 1121248..1122342 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174663 YP_001221718.1 CDS CMM_0977 NC_009480.1 1122424 1123965 D putative sugar ABC transporter, ATPase component (ZP_00225997.1| COG3845: ABC-type uncharacterized transport systems, ATPase components [Kineococcus radiotolerans SRS30216]; NP_622137.1| ABC-type sugar (aldose) transport system, ATPase component [Thermoanaerobacter tengcongensis]). pfam00005, ABC_tran,ABC transporter (duplicated).; Specificity unclear; putative sugar ABC transporter ATPase 1122424..1123965 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174615 YP_001221719.1 CDS CMM_0978 NC_009480.1 1123962 1125338 D putative sugar ABC transporter, permease component (ZP_00198294.1| COG4603: ABC-type uncharacterized transport system, permease component [Kineococcus radiotolerans SRS30216]; ZP_00330811.1| COG4603: ABC-type uncharacterized transport system, permease component [Moorella thermoacetica ATCC 39073]). pfam02653,BPD_transp_2, Branched-chain amino acid transport system / permease component. This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease, and a ribose transport system. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families).; Specificity unclear; putative sugar ABC transporter permease 1123962..1125338 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174742 YP_001221720.1 CDS CMM_0979 NC_009480.1 1125335 1126639 D putative sugar ABC transporter, permease component (ZP_00226022.1| COG1079: Uncharacterized ABC-type transport system, permease component [Kineococcus radiotolerans SRS30216]; ZP_00108155.1| COG1079: Uncharacterized ABC-type transport system, permease component [Nostoc punctiforme]). pfam02653, BPD_transp_2,Branched-chain amino acid transport system / permease component. This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease, and a ribose transport system.; Specificity unclear; putative sugar ABC transporter permease 1125335..1126639 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174700 YP_001221721.1 CDS cddA NC_009480.1 1126645 1127067 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1126645..1127067 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174808 YP_001221722.1 CDS deoA NC_009480.1 1127064 1128362 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 1127064..1128362 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175072 YP_001221723.1 CDS iunH NC_009480.1 1128418 1129353 R Inosine-uridine nucleoside N-ribohydrolase (Purine nucleosidase) (NP_738092.1| putative nucleoside hydrolase [Corynebacterium efficiens YS-314]; NP_246706.1| IunH [Pasteurella multocida Pm70]). CATALYZES THE HYDROLYSIS OF ALL OF THE COMMONLY OCCURRING PURINE AND PYRIMIDINE NUCLEOSIDES INTO RIBOSE AND THE ASSOCIATED BASE BUT HAS A PREFERENCE FOR INOSINE AND URIDINE AS SUBSTRATES. pfam01156, IU_nuc_hydro, Inosine-uridine preferring nucleoside hydrolase.; High confidence in function and specificity; inosine-uridine preferring nucleoside hydrolase complement(1128418..1129353) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174567 YP_001221724.1 CDS addA NC_009480.1 1129456 1130574 D catalyzes the formation of inosine from adenosine; adenosine deaminase 1129456..1130574 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173704 YP_001221725.1 CDS CMM_0984 NC_009480.1 1130643 1131092 D putative phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) (NP_694338.1| hypothetical protein OB3416 [Oceanobacillus iheyensis HTE831]; NP_463246.1| putative PTS enzyme II [Salmonella typhimurium LT2]). pfam00359, PTS_EIIA_2,Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.; Specificity unclear; phosphotransferase system mannitol/fructose-specific IIA component 1130643..1131092 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173312 YP_001221726.1 CDS CMM_0985 NC_009480.1 1131089 1131361 D putative phosphotransferase system, IIB component (ZP_00234701.1| PTS system, lactose/cellobiose specific IIB subunit [Listeria monocytogenes str. 1/2a F6854]; NP_979285.1| PTS system, lactose/cellobiose specific IIB subunit [Bacillus cereus ATCC 10987]). , pfam02302,PTS_IIB, PTS system, Lactose/Cellobiose specific IIB subunit.; Specificity unclear; hypothetical protein 1131089..1131361 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174282 YP_001221727.1 CDS CMM_0986 NC_009480.1 1131310 1132320 R putative membrane protein (ZP_00226020.1| hypothetical protein Krad06004090 [Kineococcus radiotolerans SRS30216]).; hypothetical protein complement(1131310..1132320) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174966 YP_001221728.1 CDS CMM_0987 NC_009480.1 1132317 1132943 R transcriptional regulator, MerR family (ZP_00227809.1| COG0789: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]; ZP_00057612.1| COG0789: Predicted transcriptional regulators [Thermobifida fusca]). smart00422, HTH_MERR,helix_turn_helix, mercury resistance; Specificity unclear; MerR family transcriptional regulator complement(1132317..1132943) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174764 YP_001221729.1 CDS manB NC_009480.1 1133031 1134734 R putative phosphomannomutase (NP_873912.1| probable phosphomannomutase [Haemophilus ducreyi 35000HP]; NP_246011.1| YhxB [Pasteurella multocida]). pfam02878,PGM_PMM_I, Phosphoglucomutase/phosphomannomutase,alpha/beta/alpha domain I. pfam02879, PGM_PMM_II,Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II. pfam00408, PGM_PMM_IV,Phosphoglucomutase/phosphomannomutase, C-terminal domain.; High confidence in function and specificity; putative phosphomannomutase complement(1133031..1134734) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174979 YP_001221730.1 CDS punA NC_009480.1 1134731 1135558 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(1134731..1135558) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175780 YP_001221731.1 CDS lpdA NC_009480.1 1135649 1137091 D catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; flavoprotein disulfide reductase 1135649..1137091 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175365 YP_001221732.1 CDS accA NC_009480.1 1137170 1138939 R Acetyl-/propionyl-coenzyme A carboxylase alpha chain [Includes: Biotin carboxylase (EC 6.3.4.14); Biotin carboxyl carrier protein (BCCP)] (ZP_00293824.1| COG4770: Acetyl/propionyl-CoA carboxylase, alpha subunit [Thermobifida fusca]; NP_629074.1| putative acyl-CoA carboxylase complex A subunit [Streptomyces coelicolor A3(2)]). THIS PROTEIN CARRIES TWO FUNCTIONS: BIOTIN CARBOXYL CARRIER PROTEIN AND BIOTIN CARBOXYLTRANSFERASE. accC: acetyl-CoA carboxylase biotin c pfam00289,CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain. pfam02786, CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain. pfam02785,Biotin_carb_C, Biotin carboxylase C-terminal domain. pfam00364, Biotin_lipoyl, Biotin-requiring enzyme.; High confidence in function and specificity; acetyl/propionyl CoA carboxylase subunit complement(1137170..1138939) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173672 YP_001221733.1 CDS CMM_0992 NC_009480.1 1139062 1139589 D hypothetical protein 1139062..1139589 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173449 YP_001221734.1 CDS CMM_0993 NC_009480.1 1139611 1140282 R putative inhibitor of septum formation (ZP_00049215.1| COG0424: Nucleotide-binding protein implicated in inhibition of septum formation [Magnetospirillum magnetotacticum]; ZP_00226343.1| COG0424: Nucleotide-binding protein implicated in inhibition of septum formation [Kineococcus radiotolerans SRS30216]). pfam02545, Maf, Maf-like protein. Maf is a putative inhibitor of septum formation in eukaryotes,bacteria, and archaea.; High confidence in function and specificity; hypothetical protein complement(1139611..1140282) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174869 YP_001221735.1 CDS CMM_0994 NC_009480.1 1140337 1141602 D putative RNA methyltransferase (ZP_00294131.1| COG2265: SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Thermobifida fusca]; ZP_00226682.1| COG2265: SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Kineococcus radiotolerans SRS30216]). pfam01938, TRAM, TRAM domain. This small domain has no known function. However it may perform a nucleic acid binding role. pfam05958, tRNA_U5-meth_tr, tRNA (Uracil-5-)-methyltransferase.; Specificity unclear; putative RNA methyltransferase 1140337..1141602 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175063 YP_001221736.1 CDS CMM_0995 NC_009480.1 1141702 1142406 D putative two component system, response regulator (NP_737890.1| putative transcription regulator [Corynebacterium efficiens YS-314]; AAP42850.1| NanT3 [Streptomyces nanchangensis]). InterPro: Response regulator receiver domain pfam00072, Response_reg,Response regulator receiver domain. pfam00196, GerE,Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two component system, response regulator 1141702..1142406 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175025 YP_001221737.1 CDS CMM_0996 NC_009480.1 1142396 1143742 D putative two-component system, sensor kinase (ZP_00121793.2| COG4585: Signal transduction histidine kinase [Bifidobacterium longum DJO10A]; AAP42852.1| NanT5 [Streptomyces nanchangensis]). pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system, sensor kinase 1142396..1143742 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175096 YP_001221738.1 CDS CMM_0997 NC_009480.1 1143739 1144761 D Hypothetical protein; hypothetical protein 1143739..1144761 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175114 YP_001221739.1 CDS CMM_0998 NC_009480.1 1145049 1145282 R hypothetical protein (YP_056397.1| hypothetical protein PPA1708 [Propionibacterium acnes KPA171202]; NP_962334.1| hypothetical protein MAP3400 [Mycobacterium avium subsp. paratuberculosis str. k10]).; hypothetical protein complement(1145049..1145282) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175150 YP_001221740.1 CDS accD NC_009480.1 1145279 1146892 R putative acetyl-/propionyl-CoA carboxylase beta chain (NP_629079.1| propionyl-CoA carboxylase complex B subunit [Streptomyces coelicolor A3(2)]; ZP_00293826.1| COG4799: Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Thermobifida fusca]). pfam01039, Carboxyl_trans, Carboxyl transferase domain. All of the members in this family are biotin dependent carboxylases.; Specificity unclear; putative acetyl/propionyl-CoA carboxylase beta chain complement(1145279..1146892) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175179 YP_001221741.1 CDS CMM_1000 NC_009480.1 1147000 1147782 D putative lipoate protein ligase (NP_788981.1| putative protein ligase [Tropheryma whipplei TW08/27]; NP_599941.1| biotin-(acetyl-CoA carboxylase) ligase [Corynebacterium glutamicum ATCC 13032]). pfam03099,BPL_LipA_LipB, Biotin/lipoate A/B protein ligase family. pfam02237, BPL_C, Biotin protein ligase C terminal domain. birA_ligase: biotin--acetyl-CoA-carboxyla; Specificity unclear; putative lipoate protein ligase 1147000..1147782 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173471 YP_001221742.1 CDS CMM_1001 NC_009480.1 1147786 1148580 D hypothetical membrane protein pfam03703, DUF304,Bacterial membrane flanked domain.; Hypothetical protein; hypothetical protein 1147786..1148580 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175266 YP_001221743.1 CDS CMM_1002 NC_009480.1 1148600 1149118 R putative membrane protein (NP_301574.1| putative membrane protein [Mycobacterium leprae TN]; ZP_00293833.1| COG2246: Predicted membrane protein [Thermobifida fusca]). pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides.; Function unclear; hypothetical protein complement(1148600..1149118) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175195 YP_001221744.1 CDS purK NC_009480.1 1149255 1150382 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1149255..1150382 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175417 YP_001221745.1 CDS purE NC_009480.1 1150437 1150961 D Phosphoribosylaminoimidazole carboxylase catalytic subunit (O67239|PUR6_AQUAE Phosphoribosylaminoimidazole carboxylase catalytic subunit (AIR carboxylase) (AIRC); ZP_00226348.1| COG0041: Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Kineococcus radiotolerans SRS30216]; pfam00731, AIRC,AIR carboxylase. Members of this family catalyse the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyse the sixth step of de novo purine biosynthesis. InterPro: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; High confidence in function and specificity; phosphoribosylaminoimidazole carboxylase catalytic subunit 1150437..1150961 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173237 YP_001221746.1 CDS CMM_1005 NC_009480.1 1150958 1152307 D putative transcriptional regulator (ZP_00292832.1| COG1316: Transcriptional regulator [Thermobifida fusca]). pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain. InterPro: Cell envelope-related transcriptional attenuator domain.; Function unclear; putative transcriptional regulator 1150958..1152307 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175348 YP_001221747.1 CDS wcqB NC_009480.1 1152323 1153507 R putative glycosyltransferase, mannosyltransferase (YP_061577.1| mannosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; AAS55730.1| putative glycosyl transferase [Aneurinibacillus thermoaerophilus]; I76776 O9 mannan biosynthesis mannosyltransferase (EC 2.4.1.-) B - Escherichia coli). pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Specificity unclear; putative glycosyltransferase,mannosyltransferase complement(1152323..1153507) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175314 YP_001221748.1 CDS wzt NC_009480.1 1153554 1154300 R putative polysaccharide ABC transporter, ATP-binding protein (ZP_00226434.1| COG1134: ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Kineococcus radiotolerans SRS30216]; NP_787162.1| ABC transporter ATP-binding protein [Tropheryma whipplei str. Twist]). pfam00005, ABC_tran,ABC transporter.; Specificity unclear; putative polysaccharide ABC transporter ATP-binding protein complement(1153554..1154300) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173560 YP_001221749.1 CDS wzm NC_009480.1 1154284 1155153 R putative polysaccharide ABC-transporter, permease component (ZP_00226433.1| COG1682: ABC-type polysaccharide/polyol phosphate export systems, permease component [Kineococcus radiotolerans SRS30216]; NP_788992.1| putative ABC transport integral membrane subunit [Tropheryma whipplei TW08/27]). pfam01061,ABC2_membrane, ABC-2 type transporter.; Specificity unclear; putative polysaccharide ABC-transporter,permease complement(1154284..1155153) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173960 YP_001221750.1 CDS rmlD NC_009480.1 1155248 1156102 R putative dTDP-4-dehydrorhamnose reductase (dTDP-L-rhamnose synthetase) (YP_061578.1| dTDP-4-dehydrorhamnose reductase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787157.1| dTDP-4-dehydrorhamnose reductase [Tropheryma whipplei str. Twist]; AAG29801.1| dTDP-4-keto-6-deoxyhexose reductase [Streptomyces rishiriensis]). pfam04321, RmlD_sub_bind, RmlD substrate binding domain. L-rhanmose is a saccharide required for the virulence of some bacteria. Its precursor, dTDP-L-rhanmose, is synthesised by four different enzymes the final one of which is RmlD. The RmlD substrate binding domain is responsible for binding a sugar nucleotide.; High confidence in function and specificity; putative dTDP-4-dehydrorhamnose reductase complement(1155248..1156102) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173842 YP_001221751.1 CDS rmlB NC_009480.1 1156099 1157088 R putative dTDP-glucose 4,6-dehydratase (YP_061579.1| thymidine diphosphoglucose 4,6-dehydratase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787158.1| dTDP-glucose 4,6-dehydratase [Tropheryma whipplei str. Twist]; AAK83290.1| DTDP-glucose 4,6-dehydratase [Saccharopolyspora spinosa]). InterPro: NAD dependent epimerase/dehydratase family. pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; High confidence in function and specificity; putative dTDP-glucose 4,6-dehydratase complement(1156099..1157088) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174905 YP_001221752.1 CDS wcqC NC_009480.1 1157269 1157721 D conserved hypothetical protein, putative sugar translocase (NP_949391.1| hypothetical protein RPA4055 [Rhodopseudomonas palustris CGA009]; NP_790903.1| membrane protein, putative [Pseudomonas syringae pv. tomato str. DC3000]; NP_636006.1| sugar translocase [Xanthomonas campestris pv. campestris str. ATCC 33913]; ZP_00231618.1| cell wall teichoic acid glycosylation protein GtcA [Listeria monocytogenes str. 4b H7858]). pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides.; putative sugar translocase 1157269..1157721 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173940 YP_001221753.1 CDS rmlC NC_009480.1 1157747 1158352 D putative dTDP-4-dehydrorhamnose 3,5-epimerase (dTDP-L-rhamnose synthetase) (YP_061580.1| dTDP-4-dehydrorhamnose 3,5-epimerase [Leifsonia xyli subsp. xyli str. CTCB07]; dTDP-L-rhamnose synthetase) (NP_963158.1| RmlC [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00908, dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. This family catalyse the isomerisation of dTDP-4-dehydro-6-deoxy -D-glucose with dTDP-4-dehydro-6-deoxy-L-mannose.; High confidence in function and specificity; dTDP-4-dehydrorhamnose 3,5-epimerase 1157747..1158352 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173577 YP_001221754.1 CDS rmlA NC_009480.1 1158356 1159219 D putative glucose-1-phosphate thymidylyltransferase (dTDP-glucose synthase) (AAN65244.1| dTDP-glucose synthase [Streptomyces roseochromogenes subsp. oscitans]; AAF67515.1| NovV [Streptomyces caeruleus]). pfam00483,NTP_transferase, Nucleotidyl transferase. This family includes a wide range of enzymes which transfer nucleotides onto phosphosugars.; High confidence in function and specificity; putative glucose-1-phosphate thymidylyltransferase 1158356..1159219 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174141 YP_001221755.1 CDS wcqD NC_009480.1 1159283 1160260 R putative NDP-sugar-epimerase (AAP69596.1| putative NDP-sugar dehydratase/epimerase [Streptomyces griseoflavus]; YP_061584.1| UDP-glucose 4-epimerase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam01370,Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Specificity unclear; putative NDP-sugar-epimerase complement(1159283..1160260) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174199 YP_001221756.1 CDS wcqE NC_009480.1 1160257 1161288 R putative glycosyl transferase (NP_108629.1| ; NP_630465.1| putative sugar transferase [Streptomyces coelicolor A3(2)]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose,dolichol phosphate and teichoic acids.; Specificity unclear; putative glycosyl transferase complement(1160257..1161288) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173551 YP_001221757.1 CDS wcqF NC_009480.1 1161285 1162139 R putative glycosyl transferase (NP_661812.1| glycosyl transferase [Chlorobium tepidum TLS]; AAN04247.1| putative glycosyl transferase [Streptomyces sp. 139]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose,dolichol phosphate and teichoic acids.; Specificity unclear; putative glycosyl transferase complement(1161285..1162139) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173593 YP_001221758.1 CDS wcqG NC_009480.1 1162412 1164625 D hypothetical membrane protein (weak similarities,ZP_00047020.1| COG4485: Predicted membrane protein [Lactobacillus gasseri]; NP_689157.1| ABC transporter,permease protein, putative [Streptococcus agalactiae 2603V/R]). weak similarity to: COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Hypothetical protein; hypothetical protein 1162412..1164625 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173617 YP_001221759.1 CDS wcqH NC_009480.1 1164622 1165584 D putative glycosyl (rhamnosyl) transferase (ZP_00226429.1| COG0463: Glycosyltransferases involved in cell wall biogenesis [Kineococcus radiotolerans SRS30216]; YP_004503.1| dTDP-rhamnosyl transferase rfbF [Thermus thermophilus HB27]; NP_964886.1| hypothetical protein LJ1030 [Lactobacillus johnsonii NCC 533]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Specificity unclear; putative glycosyltransferase 1164622..1165584 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173618 YP_001221760.1 CDS wcqI NC_009480.1 1165776 1166624 D putative glycosyl transferase (NP_810558.1| putative glycosyltransferase [Bacteroides thetaiotaomicron VPI-5482]; BAA19631.1| unnamed protein product [Actinobacillus actinomycetemcomitans]). pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Specificity unclear; putative glycosyltransferase 1165776..1166624 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173592 YP_001221761.1 CDS glfA NC_009480.1 1166692 1167855 D putative UDP-galactopyranose mutase (ZP_00226431.1| COG0562: UDP-galactopyranose mutase [Kineococcus radiotolerans SS30216]; NP_739329.1| putative UDP-galactopyranose mutase [Corynebacterium efficiens YS-314]). pfam03275, GLF, UDP-galactopyranose mutase. UDP-GALP_mutase: UDP-galactopyranose; High confidence in function and specificity; hypothetical protein 1166692..1167855 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173635 YP_001221762.1 CDS wcqJ NC_009480.1 1167855 1169873 D putative glycosyltransferase (ZP_00226432.1| COG1216: Predicted glycosyltransferases [Kineococcus radiotolerans SRS30216]; NP_218325.1| hypothetical protein Rv3808c [Mycobacterium tuberculosis H37Rv]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. InterPro: Glycosyl transferase family 2.; Specificity unclear; putative glycosyltransferase 1167855..1169873 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175297 YP_001221763.1 CDS wcqK NC_009480.1 1170018 1171847 D putative peptidoglycan-binding protein (YP_061590.1| hemagglutinin-related protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696468.1| hypothetical protein BL1304 [Bifidobacterium longum NCC2705]).; Function unclear; hypothetical protein 1170018..1171847 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173625 YP_001221764.1 CDS wcqL NC_009480.1 1172007 1172477 D conserved membrane protein (NP_949391.1| hypothetical protein RPA4055 [Rhodopseudomonas palustris CGA009]; NP_816266.1| teichoic acid glycosylation protein, putative [Enterococcus faecalis V583]). pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides.; Conserved hypothetical protein; hypothetical protein 1172007..1172477 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173632 YP_001221765.1 CDS wcqM NC_009480.1 1172505 1173797 R conserved membrane protein (YP_061600.1| exopolysaccharide production protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00110594.1| COG3307: Lipid A core - O-antigen ligase and related enzymes [Nostoc punctiforme]; ZP_00085768.1| COG3307: Lipid A core - O-antigen ligase and related enzymes [Pseudomonas fluorescens PfO-1]). potentially involved in export of polysaccharides (EPS/teichoic acids).; Function unclear; hypothetical protein complement(1172505..1173797) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173645 YP_001221766.1 CDS wzy4 NC_009480.1 1173846 1175393 R conserved membrane protein, putative polysaccharide polymerase (YP_061601.1| exopolysaccharide production protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_419318.1| conserved hypothetical protein [Caulobacter crescentus CB15]; ZP_00085768.1| COG3307: Lipid A core -O-antigen ligase and related enzymes [Pseudomonas fluorescens PfO-1]). pfam04932, Wzy_C, O-Antigen Polymerase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria.; putative polysaccharide polymerase complement(1173846..1175393) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173702 YP_001221767.1 CDS gcdH NC_009480.1 1175393 1176571 R putative glutaryl-CoA dehydrogenase (NP_821894.1| putative glutaryl-CoA dehydrogenase [Streptomyces avermitilis MA-4680]; NP_294274.1| glutaryl-CoA dehydrogenase, putative [Deinococcus radiodurans]). pfam02771, Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain. The N-terminal domain of Acyl-CoA dehydrogenase is an all-alpha domain. pfam02770, Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain. Central domain of Acyl-CoA dehydrogenase has a beta-barrel fold. pfam00441, Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain. C-terminal domain of Acyl-CoA dehydrogenase is an all-alpha, four helical up-and-down bundle.; Specificity unclear; putative glutaryl-CoA dehydrogenase complement(1175393..1176571) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174059 YP_001221768.1 CDS manA NC_009480.1 1176737 1178029 D putative mannose-6-phosphate isomerase (YP_061602.1| mannose-6-phosphate isomerase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_301594.1| putative mannose-6-phosphate isomerase [Mycobacterium leprae]). pfam01238, PMI_typeI, Phosphomannose isomerase type I. manA: mannose-6-phosphate isomerase cl; High confidence in function and specificity; putative mannose-6-phosphate isomerase 1176737..1178029 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175725 YP_001221769.1 CDS galE1 NC_009480.1 1178064 1179032 D UDP-glucose 4-epimerase (UDP-galactose 4-epimerase) (YP_061604.1| UDP-glucose 4-epimerase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627211.1| UDP-glucose 4-epimerase [Streptomyces coelicolor A3(2)]). InterPro: NAD dependent epimerase/dehydratase family pfam01370,Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; High confidence in function and specificity; hypothetical protein 1178064..1179032 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175130 YP_001221770.1 CDS whiB1 NC_009480.1 1179182 1179499 D transcriptional regulator, whiB homolog (YP_061605.1| regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789077.1| WhiB-like regulatory protein [Tropheryma whipplei TW08/27]; S20912 regulatory protein whiB - Streptomyces coelicolor). pfam02467, Whib,Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.; Hypothetical protein; transcriptional regulator whiB-like protein 1179182..1179499 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174604 YP_001221771.1 CDS wcqR NC_009480.1 1179593 1182670 D putative glycosyl transferase (NP_789078.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; ZP_00058546.1| COG1216: Predicted glycosyltransferases [Thermobifida fusca]). InterPro: Glycosyl transferase family 2 pfam00535, Glycos_transf_2,Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyl transferase 1179593..1182670 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173772 YP_001221772.1 CDS CMM_1031 NC_009480.1 1182675 1184174 D putative secreted protein (NP_789079.1| putative secreted protein [Tropheryma whipplei TW08/27]; NP_826221.1| hypothetical protein [Streptomyces avermitilis MA-4680]).; Function unclear; hypothetical protein 1182675..1184174 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173712 YP_001221773.1 CDS CMM_1032 NC_009480.1 1184261 1184704 R conserved hypothetical protein (YP_061607.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696177.1| hypothetical protein BL1005 [Bifidobacterium longum NCC2705]).; hypothetical protein complement(1184261..1184704) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175869 YP_001221774.1 CDS CMM_1033 NC_009480.1 1184750 1184965 D conserved hypothetical protein (YP_061608.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00049347.1| hypothetical protein Magn022769 [Magnetospirillum magnetotacticum]; ZP_00058543.1| hypothetical protein [Thermobifida fusca]).; hypothetical protein 1184750..1184965 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175379 YP_001221775.1 CDS manB NC_009480.1 1184968 1186395 D converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; phosphomannomutase 1184968..1186395 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175403 YP_001221776.1 CDS CMM_1035 NC_009480.1 1186485 1186817 D conserved hypothetical protein (ZP_00227420.1| COG1937: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; CAB09730.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam02583, DUF156, Uncharacterised BCR, COG1937.; Function unclear; hypothetical protein 1186485..1186817 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175848 YP_001221777.1 CDS copP NC_009480.1 1186861 1187076 D putative copper binding protein (ZP_00227421.1| COG2608: Copper chaperone [Kineococcus radiotolerans SRS30216]; ZP_00293701.1| COG2608: Copper chaperone [Thermobifida fusca]). cd00371, HMA, Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain contains two cysteine residues that are important in binding and transfer of metal ions, such as copper, cadmium, cobalt and zinc. InterPro: Heavy-metal-associated domain TIGRFAM (TIGR00003): copper-ion-binding protein; Function unclear; putative copper binding protein 1186861..1187076 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175938 YP_001221778.1 CDS copA NC_009480.1 1187078 1189552 D putative metal-transporting ATPase (AAS20130.1| metal transporter ATPase [Arthrobacter aurescens]; ZP_00227422.1| COG2217: Cation transport ATPase [Kineococcus radiotolerans SRS30216]). , cd00371, HMA,Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain contains two cysteine residues that are important in binding and transfer of metal ions, such as copper, cadmium, cobalt and zinc. , pfam00122, E1-E2_ATPase, E1-E2 ATPase. pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase.; Specificity unclear; putative metal-transporting ATPase 1187078..1189552 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173687 YP_001221779.1 CDS ahcY NC_009480.1 1189615 1191099 D catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 1189615..1191099 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173633 YP_001221780.1 CDS CMM_1039 NC_009480.1 1191194 1192009 R conserved membrane protein (ZP_00228191.1| COG1714: Predicted membrane protein/domain [Kineococcus radiotolerans SRS30216]; ZP_00058535.1| COG1714: Predicted membrane protein/domain [Thermobifida fusca]). pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown.; Hypothetical protein; hypothetical protein complement(1191194..1192009) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172938 YP_001221781.1 CDS CMM_1040 NC_009480.1 1192080 1193075 D conserved membrane protein (ZP_00228195.1| COG1300: Uncharacterized membrane protein [Kineococcus radiotolerans SRS30216]; ZP_00058534.1| COG1300: Uncharacterized membrane protein [Thermobifida fusca]). pfam01944, DUF95, Integral membrane protein DUF95. Members of this family have several predicted transmembrane regions. The function of this family is unknown.; Function unclear; hypothetical protein 1192080..1193075 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175761 YP_001221782.1 CDS bglK NC_009480.1 1193129 1195615 R putative beta-glucosidase (glycosyl hydrolase,family3) (Beta-D- glucoside glucohydrolase) (NP_630676.1| putative beta-glucosidase [Streptomyces coelicolor A3(2)]; ZP_00019622.1| hypothetical protein [Chloroflexus aurantiacus]). pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915,Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain. InterPro: Glycoside hydrolase family 3 C terminal; Specificity unclear; beta-glucosidase complement(1193129..1195615) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175748 YP_001221783.1 CDS CMM_1042 NC_009480.1 1195669 1196949 R putative MFS permease (CAD47966.1| hypothetical protein [Arthrobacter nicotinovorans]; AAL78050.1| ORFB [Saccharopolyspora erythraea]). pfam00083, Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters.; Specificity unclear; putative MFS permease complement(1195669..1196949) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173523 YP_001221784.1 CDS CMM_1043 NC_009480.1 1197061 1197702 D putative transcriptional regulator, TetR family (ZP_00192310.3| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; ZP_00126888.1| COG1309: Transcriptional regulator [Pseudomonas syringae pv. syringae B728a]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 1197061..1197702 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175744 YP_001221785.1 CDS CMM_1044 NC_009480.1 1197725 1199032 R conserved hypothetical protein (CAA18015.1| POSSIBLE CONSERVED MEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_627241.1| putative lipoprotein [Streptomyces coelicolor A3(2)]). pfam01882, DUF58,Protein of unknown function DUF58. This family of prokaryotic proteins have no known function.; Function unclear; hypothetical protein complement(1197725..1199032) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175719 YP_001221786.1 CDS CMM_1045 NC_009480.1 1199047 1200000 R putative regulatory protein (NP_826235.1| putative regulatory protein [Streptomyces avermitilis MA-4680]; ZP_00058532.1| COG0714: MoxR-like ATPases [Thermobifida fusca]).; Specificity unclear; putative regulatory protein complement(1199047..1200000) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175722 YP_001221787.1 CDS CMM_1046 NC_009480.1 1199997 1201259 R conserved hypothetical protein (NP_338346.1| hypothetical protein [Mycobacterium tuberculosis CDC1551]; NP_627239.1| putative secreted protein [Streptomyces coelicolor A3(2)]).; Function unclear; hypothetical protein complement(1199997..1201259) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175731 YP_001221788.1 CDS CMM_1047 NC_009480.1 1201256 1201942 R conserved hypothetical protein (YP_061611.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826237.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). kdpC: potassium-transporting ATPase C; hypothetical protein complement(1201256..1201942) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175660 YP_001221789.1 CDS CMM_1048 NC_009480.1 1201939 1203135 R conserved membrane protein (YP_061612.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07] ; ZP_00225539.1| hypothetical protein Krad06004829 [Kineococcus radiotolerans SRS30216]).; Conserved hypothetical protein; hypothetical protein complement(1201939..1203135) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175711 YP_001221790.1 CDS CMM_1049 NC_009480.1 1203247 1203927 D putative two-component system response regulator (YP_061613.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058528.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Thermobifida fusca]). pfam00072, Response_reg, Response regulator receiver domain. pfam00486, Trans_reg_C,Transcriptional regulatory protein, C terminal. InterPro: Response regulator receiver domain.; Specificity unclear; putative two-component system response regulator 1203247..1203927 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175633 YP_001221791.1 CDS CMM_1050 NC_009480.1 1203932 1205566 D putative two-component system sensor kinase (YP_061614.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627234.1| putative two-component system histidine kinase [Streptomyces coelicolor A3(2)]). pfam00672, HAMP, HAMP domain. pfam00512, HisKA, His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 1203932..1205566 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175688 YP_001221792.1 CDS CMM_1051 NC_009480.1 1205550 1207277 D conserved hypothetical protein (YP_061615.1| lipoprotein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056043.1| membrane spanning lipoprotein [Propionibacterium acnes KPA171202]). ogg: 8-oxoguanine DNA-glycosylase (ogg); lipoprotein LpqB 1205550..1207277 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175630 YP_001221793.1 CDS CMM_1052 NC_009480.1 1207348 1208151 D putative amidophosphoribosyltransferase (YP_061616.1| competence protein F [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056042.1| putative amidophosphoribosyltransferase [Propionibacterium acnes KPA171202]). weak similarity to: pfam00156, Pribosyltran,Phosphoribosyl transferase domain.; Conserved hypothetical protein; putative amidophosphoribosyltransferase 1207348..1208151 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175648 YP_001221794.1 CDS CMM_1053 NC_009480.1 1208306 1208995 D putative ribosome-associated protein (YP_061617.1| sigma-54 modulation protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228969.1| COG1544: Ribosome-associated protein Y (PSrp-1) [Kineococcus radiotolerans SRS30216]). pfam02482, Ribosomal_S30AE, Sigma 54 modulation protein / S30EA ribosomal protein.; Function unclear; putative ribosome-associated protein 1208306..1208995 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175619 YP_001221795.1 CDS secA NC_009480.1 1209195 1212020 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1209195..1212020 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175626 YP_001221796.1 CDS CMM_1055 NC_009480.1 1212148 1212735 R hypothetical protein (ZP_00192100.2| hypothetical protein Krad06000007 [Kineococcus radiotolerans SRS30216]; ZP_00294296.1| hypothetical protein Tfus02000501 [Thermobifida fusca]).; hypothetical protein complement(1212148..1212735) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175541 YP_001221797.1 CDS CMM_1056 NC_009480.1 1212939 1213544 D hypothetical protein (ZP_00199350.1| hypothetical protein Krad06000009 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1212939..1213544 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175600 YP_001221798.1 CDS CMM_1057 NC_009480.1 1213614 1214252 D hypothetical protein (NP_789084.1| putative membrane/secreted protein [Tropheryma whipplei TW08/27]; ZP_00228975.1| hypothetical protein Krad06000011 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1213614..1214252 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175589 YP_001221799.1 CDS CMM_1058 NC_009480.1 1214954 1215841 D Region start changed from 1215161 to 1215047 (114 bases); putative septum formation inhibitor-activating ATPase 1214954..1215841 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175610 YP_001221800.1 CDS CMM_1059 NC_009480.1 1215851 1217356 D putative two-component system sensor kinase (ZP_00228292.1| COG3920: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]; NP_824193.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal.; Specificity unclear; putative two-component system sensor kinase 1215851..1217356 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175584 YP_001221801.1 CDS whiB2 NC_009480.1 1217450 1217698 R putative transcriptional regulator (CAB08318.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB1 [Mycobacterium tuberculosis H37Rv]; NP_696183.1| WhiB-type transcription regulator [Bifidobacterium longum NCC2705]). pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria,required for differentiation and sporulation.; Function unclear; putative transcriptional regulator, WhiB-like complement(1217450..1217698) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175591 YP_001221802.1 CDS CMM_1061 NC_009480.1 1217945 1218376 D hypothetical membrane protein (YP_062753.1| hypothetical protein Lxx19280 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228293.1| hypothetical protein Krad06001594 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1217945..1218376 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173706 YP_001221803.1 CDS bcp NC_009480.1 1218407 1218886 R putative alkyl hydroperoxide reductase (bacterioferritin comigratory protein) (NP_961263.1| Bcp [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_826353.1| putative AhpC/TSA family protein [Streptomyces avermitilis MA-4680]). pfam00578, AhpC-TSA,AhpC/TSA family. This family contains proteins related to alkyl hydroperoxide reductase (AhpC) and thiol specific antioxidant (TSA).; Specificity unclear; putative alkyl hydroperoxide reductase complement(1218407..1218886) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175566 YP_001221804.1 CDS CMM_1063 NC_009480.1 1219388 1219882 D putative transcription factor (ZP_00198110.2| COG1329: Transcriptional regulators, ; NP_301347.1| putative transcription factor [Mycobacterium leprae]). pfam02559, CarD_TRCF, CarD-like/TRCF domain. InterPro: Transcription factor CarD; Function unclear; putative transcription factor 1219388..1219882 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175272 YP_001221805.1 CDS CMM_1064 NC_009480.1 1220007 1220237 D hypothetical protein 1220007..1220237 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175576 YP_001221806.1 CDS CMM_1065 NC_009480.1 1220385 1221230 D conserved hypothetical protein (ZP_00226454.1| hypothetical protein Krad06003337 [Kineococcus radiotolerans SRS30216]; NP_627325.1| putative lipoprotein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1220385..1221230 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175559 YP_001221807.1 CDS CMM_1066 NC_009480.1 1221227 1221718 D hypothetical protein 1221227..1221718 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175556 YP_001221808.1 CDS ansP NC_009480.1 1221729 1223261 R putative L-asparagine permease, APC family (YP_062976.1| L-asparagine permease [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226832.1| COG1113: Gamma-aminobutyrate permease and related permeases [Kineococcus radiotolerans SRS30216]). pfam00324, AA_permease, Amino acid permease. InterPro: Amino acid permease; Specificity unclear; L-asparagine permease complement(1221729..1223261) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175547 YP_001221809.1 CDS CMM_1068 NC_009480.1 1223358 1223921 D hypothetical protein 1223358..1223921 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175913 YP_001221810.1 CDS CMM_1069 NC_009480.1 1223970 1225298 R putative MFS permease (YP_061411.1| integral membrane efflux protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00283009.1| COG0477: Permeases of the major facilitator superfamily [Burkholderia fungorum LB400]). TIGRFAM( TIGR00900): H+ Antiporter protein; Specificity unclear; putative MFS permease complement(1223970..1225298) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175532 YP_001221811.1 CDS CMM_1070 NC_009480.1 1225295 1225717 R putative transcriptional regulator, MarR family (NP_959753.1| hypothetical protein MAP0819 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_825072.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator complement(1225295..1225717) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175498 YP_001221812.1 CDS CMM_1071 NC_009480.1 1225905 1226081 D hypothetical protein 1225905..1226081 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175507 YP_001221813.1 CDS CMM_1072 NC_009480.1 1226186 1227004 D putative hydrolase/acyltransferase (NP_532260.1| hydrolase [Agrobacterium tumefaciens str. C58]; NP_981307.1| hydrolase, alpha/beta fold family [Bacillus cereus ATCC 10987]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. acid_CoA_mut_C: methylmalonyl-CoA muta; Function unclear; putative hydrolase/acyltransferase 1226186..1227004 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175479 YP_001221814.1 CDS CMM_1073 NC_009480.1 1227054 1228922 R putative glycosyl hydrolase, family 15 (YP_062268.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00292808.1| COG3387: Glucoamylase and related glycosyl hydrolases [Thermobifida fusca]). pfam00723, Glyco_hydro_15, Glycosyl hydrolases family 15.; Function unclear; glycoside hydrolase family protein complement(1227054..1228922) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175492 YP_001221815.1 CDS zwfB NC_009480.1 1228980 1230362 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1228980..1230362 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175454 YP_001221816.1 CDS CMM_1075 NC_009480.1 1230394 1231041 R hypothetical protein complement(1230394..1231041) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174396 YP_001221817.1 CDS CMM_1076 NC_009480.1 1231254 1232483 D putative small-conductance mechanosensitive channel (ZP_00227048.1| COG0668: Small-conductance mechanosensitive channel [Kineococcus radiotolerans SRS30216]; ZP_00023357.1| COG0668: Small-conductance mechanosensitive channel [Ralstonia metallidurans]). pfam00924, MS_channel, Mechanosensitive ion channel.; Function unclear; putative small-conductance mechanosensitive channel 1231254..1232483 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175485 YP_001221818.1 CDS arsB NC_009480.1 1232898 1234052 D putative arsenate permease, ArsB family (Arsenic efflux pump protein)(YP_062266.1| arsenical pump membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_736635.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00226785.1| COG1055: Na+/H+ antiporter NhaD and related arsenite permeases [Kineococcus radiotolerans SRS30216]). Involved in arsenical resistance. Thought to form the channel of an arsenite pump. 2a45: arsenical pump membrane protein pfam02040, ArsB, Arsenical pump membrane protein.; Specificity unclear; ArsB family arsenate permease 1232898..1234052 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175442 YP_001221819.1 CDS CMM_1078 NC_009480.1 1234135 1234713 D putative transcriptional regulator, TetR family (NP_959728.1| hypothetical protein MAP0794 [Mycobacterium avium subsp. paratuberculosis str. k10]; AAD13556.1| LanK [Streptomyces cyanogenus]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 1234135..1234713 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173216 YP_001221820.1 CDS CMM_1079 NC_009480.1 1234760 1237708 D putative drug exporter, RND family (YP_054789.1| putative membrane transport protein [Propionibacterium acnes KPA171202]; NP_824795.1| putative drug exporters of the RND superfamily [Streptomyces avermitilis MA-4680]). actII: Transport protein; Specificity unclear; RND superfamily drug exporter 1234760..1237708 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175471 YP_001221821.1 CDS CMM_1080 NC_009480.1 1237705 1239600 D conserved membrane protein (NP_961301.1| hypothetical protein MAP2367c [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_827281.1| putative membrane protein [Streptomyces avermitilis MA-4680]). Mtu_efflux: ABC transporter efflux pro; Function unclear; hypothetical protein 1237705..1239600 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175239 YP_001221822.1 CDS CMM_1081 NC_009480.1 1239603 1241030 D hypothetical protein 1239603..1241030 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175432 YP_001221823.1 CDS CMM_1082 NC_009480.1 1241105 1241407 R conserved hypothetical protein, putative monooxygenase (ZP_00226413.1| COG1359: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_959730.1| hypothetical protein MAP0796c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam03992, ABM,Antibiotic biosynthesis monooxygenase.; putative monooxygenase complement(1241105..1241407) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175102 YP_001221824.1 CDS CMM_1083 NC_009480.1 1241582 1242457 R putative sugar phosphate isomerase/epimerase (NP_627556.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00057048.1| COG1082: Sugar phosphate isomerases/epimerases [Thermobifida fusca]). pfam01261, AP_endonuc_2, AP endonuclease family 2.; Specificity unclear; hypothetical protein complement(1241582..1242457) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175806 YP_001221825.1 CDS CMM_1084 NC_009480.1 1242606 1243430 D conserved hypothetical protein, putative sugar kinase (NP_601735.1| hypothetical protein [Corynebacterium glutamicum ATCC 13032]; ZP_00225866.1| COG3001: Fructosamine-3-kinase [Kineococcus radiotolerans SRS30216]). pfam03881, Fructosamin_kin, Fructosamine kinase. This family includes eukaryotic fructosamine-3-kinase enzymes. The family also includes bacterial members that have not been characterised but probably have a similar or identical function.; putative sugar kinase 1242606..1243430 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174790 YP_001221826.1 CDS otsA NC_009480.1 1243531 1245126 D putative trehalose-phosphate synthase (UDP-glucose-glucosephosphate glucosyltransferase) (YP_062264.1| trehalose-6-phosphate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225984.1| COG0380: Trehalose-6-phosphate synthase [Kineococcus radiotolerans SRS30216]). pfam00982, Glyco_transf_20, Glycosyltransferase family 20.; High confidence in function and specificity; putative trehalose-phosphate synthase 1243531..1245126 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175256 YP_001221827.1 CDS otsB NC_009480.1 1245132 1245959 D putative trehalose-phosphatase (Trehalose 6-phosphate phosphatase) (ZP_00225983.1| COG1877: Trehalose-6-phosphatase [Kineococcus radiotolerans SRS30216]; NP_940299.1| Putative trehalose-phosphatase [Corynebacterium diphtheriae]). pfam02358,Trehalose_PPase, Trehalose-phosphatase. otsB: trehalose-phosphatase.; High confidence in function and specificity; putative trehalose-phosphatase 1245132..1245959 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175662 YP_001221828.1 CDS mnhAB NC_009480.1 1246033 1249041 D subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit A 1246033..1249041 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175252 YP_001221829.1 CDS mnhC NC_009480.1 1249038 1249598 D putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase (ZP_00226457.1| COG1006: Multisubunit Na+/H+ antiporter, MnhC subunit [Kineococcus radiotolerans SRS30216]; NP_739178.1| putative Na+/H+ antiporter [Corynebacterium efficiens YS-314]). pfam00420,Oxidored_q2, NADH-ubiquinone/plastoquinone oxidoreductase chain 4L. TIGRFAM (TIGR00941): Multicomponent Na+:H+ antiporter.; High confidence in function and specificity; putative Na+/H+ antiporter subunit 1249038..1249598 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175605 YP_001221830.1 CDS mnhD NC_009480.1 1249595 1251187 D subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 1249595..1251187 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172993 YP_001221831.1 CDS mnhE NC_009480.1 1251184 1251858 D subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit E 1251184..1251858 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173988 YP_001221832.1 CDS mnhF NC_009480.1 1251855 1252130 D putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase (ZP_00292641.1| hypothetical protein Tfus02001919 [Thermobifida fusca]; AAR35714.1| monovalent cation/proton antiporter, MrpF/PhaF family [Geobacter sulfurreducens PCA]).; High confidence in function and specificity; putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase 1251855..1252130 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175439 YP_001221833.1 CDS mnhG NC_009480.1 1252127 1252699 D putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase (ZP_00292640.1| COG1320: Multisubunit Na+/H+ antiporter, MnhG subunit [Thermobifida fusca]; ZP_00198672.2| COG1320: Multisubunit Na+/H+ antiporter, MnhG subunit [Kineococcus radiotolerans SRS30216]). pfam03334, PhaG_MnhG_YufB, Na+/H+ antiporter subunit.; Family membership; putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase 1252127..1252699 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173653 YP_001221834.1 CDS ilvD NC_009480.1 1252765 1254459 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1252765..1254459 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174345 YP_001221835.1 CDS ilvB NC_009480.1 1254456 1256339 D acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 1 catalytic subunit 1254456..1256339 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174479 YP_001221836.1 CDS ilvH NC_009480.1 1256336 1256845 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1256336..1256845 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174379 YP_001221837.1 CDS ilvC NC_009480.1 1257014 1258039 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1257014..1258039 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173472 YP_001221838.1 CDS CMM_1097 NC_009480.1 1258173 1258706 D Hypothetical protein; hypothetical protein 1258173..1258706 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174982 YP_001221839.1 CDS CMM_1098 NC_009480.1 1258703 1259071 D Hypothetical protein; hypothetical protein 1258703..1259071 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175090 YP_001221840.1 CDS CMM_1099 NC_009480.1 1259081 1259482 R conserved membrane protein (NP_869710.1| conserved hypothetical protein-putative transmembrane protein [Pirellula sp. 1]; ZP_00110025.1| COG4270: Predicted membrane protein [Nostoc punctiforme]).; hypothetical protein complement(1259081..1259482) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175933 YP_001221841.1 CDS serA NC_009480.1 1259548 1261137 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1259548..1261137 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175949 YP_001221842.1 CDS CMM_1101 NC_009480.1 1261216 1261839 R putative transcriptional regulator, TetR family (ZP_00198420.1| hypothetical protein Krad024089 [Kineococcus radiotolerans SRS30216]; NP_691916.1| transcriptional regulator [Oceanobacillus iheyensis HTE831]). InterPro: Bacterial regulatory proteins TetR family pfam00440, TetR_N, Bacterial regulatory proteins,tetR family.; Specificity unclear; TetR family transcriptional regulator complement(1261216..1261839) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175137 YP_001221843.1 CDS CMM_1102 NC_009480.1 1261961 1263502 D putative efflux MFS permease (CAE15934.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1]; AAN50737.1| possible transmembrane-transport protein [Leptospira interrogans serovar lai str. 56601]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative efflux MFS permease 1261961..1263502 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173740 YP_001221844.1 CDS CMM_1103 NC_009480.1 1263580 1263834 R hypothetical membrane protein (NP_627991.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00225753.1| hypothetical protein Krad06004516 [Kineococcus radiotolerans SRS30216]).; hypothetical protein complement(1263580..1263834) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174130 YP_001221845.1 CDS leuB NC_009480.1 1263947 1265014 D catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1263947..1265014 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175261 YP_001221846.1 CDS ilvE NC_009480.1 1265023 1266153 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1265023..1266153 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174161 YP_001221847.1 CDS CMM_1106 NC_009480.1 1266211 1266984 D putative 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase, putative fumarylacetoacetate (FAA) hydrolase (YP_062251.1| 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293380.1| COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Thermobifida fusca]). pfam01557,FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family.; Function unclear; hypothetical protein 1266211..1266984 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173337 YP_001221848.1 CDS CMM_1107 NC_009480.1 1266987 1267745 D hypothetical protein 1266987..1267745 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174336 YP_001221849.1 CDS gltX NC_009480.1 1267759 1269279 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1267759..1269279 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175327 YP_001221850.1 CDS trxB2 NC_009480.1 1269272 1270222 D putative thioredoxin reductase (YP_062249.1| pyridine nucleotide- disulfide oxidoreductase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_028840.1| thioredoxin reductase, putative [Bacillus anthracis str. Sterne]). ,pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases.; Function unclear; putative thioredoxin reductase 1269272..1270222 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174201 YP_001221851.1 CDS CMM_1110 NC_009480.1 1270661 1274278 D conserved hypothetical protein (AAB84461.1| DNA-binding protein [Bacillus subtilis]; AAO79850.1| conserved hypothetical protein [Bacteroides thetaiotaomicron VPI-5482]).; hypothetical protein 1270661..1274278 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174660 YP_001221852.1 CDS CMM_1111 NC_009480.1 1274459 1274689 D hypothetical protein (NP_737865.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; hypothetical protein 1274459..1274689 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174410 YP_001221853.1 CDS CMM_1112 NC_009480.1 1274834 1275844 R putative K+ channel protein, beta subunit (ZP_00228108.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; CAD19081.1| potassium channel beta chain [Stigmatella aurantiaca]). Pfam: Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity. Voltage-gated potassium channel beta-1 subunit (K+ channel beta-1 subunit) (Kv-beta-1). ACCESSORY POTASSIUM CHANNEL PROTEIN WHICH MODULATES THE ACTIVITY OF THE PORE-FORMING ALPHA SUBUNIT (BY SIMILARITY). InterPro: Aldo/keto reductase family; Function unclear; putative K+ channel protein subunit beta complement(1274834..1275844) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174274 YP_001221854.1 CDS CMM_1113 NC_009480.1 1275979 1276989 R putative potassium channel protein subunit (ZP_00228108.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; CAD19081.1| potassium channel beta chain [Stigmatella aurantiaca]). pfam00248,Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.; Function unclear; putative potassium channel protein subunit complement(1275979..1276989) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174535 YP_001221855.1 CDS CMM_1114 NC_009480.1 1277057 1277671 R putative transcriptional regulator, TetR family (NP_624827.1| putative regulatory protein [Streptomyces coelicolor A3(2)]; NP_959089.1| hypothetical protein MAP0155 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00440, TetR_N, Bacterial regulatory proteins,tetR family.; Specificity unclear; TetR family transcriptional regulator complement(1277057..1277671) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173865 YP_001221856.1 CDS CMM_1115 NC_009480.1 1277727 1278524 D putative short-chain dehydrogenase (ZP_00229050.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; CAB58271.1| putative dehydrogenase (putative secreted protein) [Streptomyces coelicolor A3(2)]). pfam00106, adh_short,short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Function unclear; putative short chain dehydrogenase 1277727..1278524 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173793 YP_001221857.1 CDS CMM_1116 NC_009480.1 1278593 1279696 R conserved membrane protein, TerC family (NP_738469.1| putative integral membrane export protein [Corynebacterium efficiens YS-314]; YP_061942.1| membrane protein, tellurium resistance [Leifsonia xyli subsp. xyli str. CTCB07]). pfam03741, TerC, Integral membrane protein TerC family. This family contains a number of integral membrane proteins that also contains the TerC protein. TerC has been implicated in resistance to tellurium. This protein may be involved in efflux of tellurium ions.; Function unclear; TerC family membrane protein complement(1278593..1279696) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174894 YP_001221858.1 CDS CMM_1117 NC_009480.1 1279936 1280352 R Hypothetical protein; hypothetical protein complement(1279936..1280352) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175592 YP_001221859.1 CDS CMM_1118 NC_009480.1 1280395 1281033 R putative Zn-dependant hydrolase (NP_335238.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]; NP_630432.1| conserved hypothetical protein SC3A7.08 [Streptomyces coelicolor A3(2)]). pfam00753,Lactamase_B, Metallo-beta-lactamase superfamily. menD: 2-succinyl-6-hydroxy-24-cyclohex; Function unclear; putative Zn-dependent hydrolase complement(1280395..1281033) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174901 YP_001221860.1 CDS CMM_1119 NC_009480.1 1281390 1282106 D putative serine protease, family S51 , related to cyanophycinase (NP_824488.1| hypothetical protein [Streptomyces avermitilis MA-4680]; YP_056776.1| hypothetical protein PPA2111 [Propionibacterium acnes KPA171202]). pfam03575, Peptidase_S51, Peptidase family S51.; Function unclear; S51 family peptidase 1281390..1282106 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175652 YP_001221861.1 CDS ungA NC_009480.1 1282117 1282803 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1282117..1282803 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175346 YP_001221862.1 CDS CMM_1121 NC_009480.1 1282857 1283546 D putative acetyltransferase (YP_062723.1| phosphinothricin acetyltransferase protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00054060.1| COG1247: Sortase and related acyltransferases [Magnetospirillum magnetotacticum]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 1282857..1283546 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173297 YP_001221863.1 CDS CMM_1122 NC_009480.1 1283428 1284360 R Region start changed from 1284588 to 1284360 (-228 bases); putative membrane bound protease complement(1283428..1284360) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174755 YP_001221864.1 CDS sgaH NC_009480.1 1286708 1287331 R putative hexulose-6-phosphate synthase (D-arabino 3-hexulose 6-phosphate formaldehyde lyase) (CAD28138.1| putative 3-hexulose-6-phosphate synthase [Rhodococcus opacus]; BAA90546.1| 3-hexulose-6-phosphate synthase [Mycobacterium gastri]). pfam00215, OMPdecase, Orotidine 5'-phosphate decarboxylase / HUMPS family.; High confidence in function and specificity; putative hexulose-6-phosphate synthase complement(1286708..1287331) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175804 YP_001221865.1 CDS CMM_1124 NC_009480.1 1287384 1287992 R putative 6-phospho-3-hexuloisomerase (BAA90545.1| 6-phospho- 3-hexuloisomerase [Mycobacterium gastri]; CAD28139.1| putative 6-phospho-3-hexuloisomerase [Rhodococcus opacus]). pfam01380, SIS, SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars. Presumably the SIS domains bind to the end-product of the pathway.; Function unclear; putative 6-phospho-3-hexuloisomerase complement(1287384..1287992) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175046 YP_001221866.1 CDS CMM_1125 NC_009480.1 1288259 1289437 D putative transcriptional regulator, LuxR family (CAD28140.1| putative LuxR-like transcriptional regulator [Rhodococcus opacus]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. pfam00196,GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; LuxR family transcriptional regulator 1288259..1289437 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175269 YP_001221867.1 CDS CMM_1126 NC_009480.1 1289562 1291709 D putative 5'-nucleotidase (YP_056763.1| 5'-nucleotidase/2',3'-cyclic phosphodiesterase or related esterase [Propionibacterium acnes KPA171202]; NP_736947.1| 5'-nucleotidase [Corynebacterium efficiens YS-314]). pfam00149, Metallophos, Calcineurin-like phosphoesterase. pfam02872, 5_nucleotid_C, 5'-nucleotidase, C-terminal domain. InterPro: 5-Nucleotidase; Function unclear; putative 5'-nucleotidase 1289562..1291709 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175718 YP_001221868.1 CDS CMM_1127 NC_009480.1 1291820 1293247 D putative Asp/Glu-tRNA amidotransferase (ZP_00058755.1| COG0154: Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Thermobifida fusca]; ZP_00111119.1| COG0154: Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Nostoc punctiforme]). pfam01425, Amidase,Amidase.; Specificity unclear; putative Asp/Glu-tRNA amidotransferase 1291820..1293247 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175799 YP_001221869.1 CDS CMM_1128 NC_009480.1 1293257 1293994 R conserved membrane protein (NP_738052.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; NP_631844.1| putative membrane protein. [Streptomyces coelicolor A3(2)]). pfam01925, DUF81, Domain of unknown function DUF81. This integral membrane protein family has no known function.; Function unclear; hypothetical protein complement(1293257..1293994) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173844 YP_001221870.1 CDS CMM_1129 NC_009480.1 1294075 1295067 D putative siderophore-interacting protein (ZP_00227633.1| COG2375: Siderophore-interacting protein [Kineococcus radiotolerans SRS30216]; NP_737293.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). involved in the intracellular removol of iron from siderophores. pfam04954, SIP, Siderophore-interacting protein.; Specificity unclear; putative siderophore-interacting protein 1294075..1295067 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175773 YP_001221871.1 CDS CMM_1130 NC_009480.1 1295500 1296378 R putative short-chain alcohol dehydrogenase (ZP_00227858.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; YP_061632.1| oxidoreductase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short chain alcohol dehydrogenase complement(1295500..1296378) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174599 YP_001221872.1 CDS CMM_1131 NC_009480.1 1296375 1296767 R hypothetical protein (ZP_00299320.1| hypothetical protein Gmet02002474 [Geobacter metallireducens GS-15]; ZP_00189534.3| hypothetical protein Krad06003867 [Kineococcus radiotolerans SRS30216]).; hypothetical protein complement(1296375..1296767) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175695 YP_001221873.1 CDS CMM_1132 NC_009480.1 1296764 1298197 R putative pyridine nucleotide-disulphide oxidoreductase (CAA73871.1| mercuric reductase/glutathione reductase/ dihydrolipoamide dehydrogenase [Mycobacterium tuberculosis]; NP_821842.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]). pfam00070, Pyr_redox,Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. pfam02852,Pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.; Function unclear; putative pyridine nucleotide-disulphide oxidoreductase complement(1296764..1298197) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175802 YP_001221874.1 CDS echA NC_009480.1 1298254 1299093 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(1298254..1299093) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175058 YP_001221875.1 CDS CMM_1134 NC_009480.1 1299162 1300004 R putative arginase (YP_061703.1| arginase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291576.1| COG0010: Arginase/agmatinase/ formimionoglutamate hydrolase,arginase family [Thermobifida fusca]). pfam00491,Arginase, Arginase family.; Specificity unclear; hypothetical protein complement(1299162..1300004) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175514 YP_001221876.1 CDS CMM_1135 NC_009480.1 1300110 1300760 R putative F420-dependent NADP reductase (ZP_00228826.1| COG2085: Predicted dinucleotide-binding enzymes [Kineococcus radiotolerans SRS30216]; AAR32680.1| conserved hypothetical protein [Streptomyces hygroscopicus]). pfam03807, F420_oxidored, NADP oxidoreductase coenzyme F420-dependent.; Function unclear; putative F420-dependent NADP reductase complement(1300110..1300760) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174496 YP_001221877.1 CDS CMM_1136 NC_009480.1 1300855 1301598 R conserved hypothetical protein, ; ZP_00326969.1| COG1842: Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Trichodesmium erythraeum IMS101]). pfam04012, PspA_IM30, PspA/IM30 family.; Function unclear; hypothetical protein complement(1300855..1301598) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175088 YP_001221878.1 CDS CMM_1137 NC_009480.1 1301683 1303725 R conserved hypothetical protein (NP_336889.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]; ZP_00227832.1| COG1512: Beta-propeller domains of methanol dehydrogenase type [Kineococcus radiotolerans SRS30216]). pfam04536, DUF477, Domain of unknown function (DUF477). The function of this presumed domain is unknown. EIIA-LAC: PTS system lactose-specifi; hypothetical protein complement(1301683..1303725) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174578 YP_001221879.1 CDS CMM_1138 NC_009480.1 1303814 1304239 R hypothetical protein (NP_336075.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]).; hypothetical protein complement(1303814..1304239) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175430 YP_001221880.1 CDS CMM_1139 NC_009480.1 1304368 1304679 R hypothetical protein complement(1304368..1304679) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174505 YP_001221881.1 CDS CMM_1140 NC_009480.1 1305414 1306103 D putative pyridoxamine-phosphate oxidase (NP_628586.1| putative oxidase [Streptomyces coelicolor A3(2)]; ZP_00013664.1| COG0259: Pyridoxamine-phosphate oxidase [Rhodospirillum rubrum]). pfam01243,Pyridox_oxidase, Pyridoxamine 5'-phosphate oxidase.; Specificity unclear; putative pyridoxamine-phosphate oxidase 1305414..1306103 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173323 YP_001221882.1 CDS CMM_1141 NC_009480.1 1306214 1306984 D putative glutamine amidotransferase (ZP_00331246.1| COG2071: Predicted glutamine amidotransferases [Moorella thermoacetica ATCC 39073]; NP_302088.1| possible amidotransferase [Mycobacterium leprae TN]). pfam00117,GATase, Glutamine amidotransferase class-I. InterPro: Glutamine amidotransferase class-I; Function unclear; putative glutamine amidotransferase 1306214..1306984 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174364 YP_001221883.1 CDS CMM_1142 NC_009480.1 1307034 1307789 R putative short chain alcohol dehydrogenase (AAO42633.1| putative short-chain dehydrogenase [Ralstonia eutropha]; AAO57656.1| oxidoreductase, short chain dehydrogenase/reductase family [Pseudomonas syringae pv. tomato str. DC3000] pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short chain alcohol dehydrogenase complement(1307034..1307789) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174843 YP_001221884.1 CDS CMM_1143 NC_009480.1 1307786 1308553 R putative short chain alcohol dehydrogenase (AAO57657.1| oxidoreductase, short chain dehydrogenase/reductase family [Pseudomonas syringae pv. tomato str. DC3000]; ZP_00126580.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Pseudomonas syringae pv. syringae B728a]). InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily pfam00106,adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; High confidence in function and specificity; putative short chain alcohol dehydrogenase complement(1307786..1308553) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174580 YP_001221885.1 CDS CMM_1144 NC_009480.1 1308550 1309935 R putative MFS permease (ZP_00126581.1| COG0477: Permeases of the major facilitator superfamily [Pseudomonas syringae pv. syringae B728a]; NP_992822.1| putative sugar transporter [Yersinia pestis biovar Medievalis str. 91001]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS permease complement(1308550..1309935) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173861 YP_001221886.1 CDS CMM_1145 NC_009480.1 1309970 1310860 R putative deacetylase (ZP_00126582.1| COG0726: Predicted xylanase/chitin deacetylase [Pseudomonas syringae pv. syringae B728a]; NP_738966.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam01522, Polysacc_deac_1, Polysaccharide deacetylase. This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It also includes chitin deacetylase from yeast, and endoxylanases which hydrolyses glucosidic bonds in xylan.; Specificity unclear; putative deacetylase complement(1309970..1310860) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174633 YP_001221887.1 CDS CMM_1146 NC_009480.1 1310886 1311911 R Region start changed from 1311968 to 1311911 (-57 bases); putative asparaginase complement(1310886..1311911) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174734 YP_001221888.1 CDS CMM_1147 NC_009480.1 1312083 1313111 D putative transcriptional regulator, LacI family (NP_886234.1| LacI family transcriptional regulator [Bordetella parapertussis 12822]; NP_535765.1| transcriptional regulator, LacI family [Agrobacterium tumefaciens str. C58]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; LacI family transcriptional regulator 1312083..1313111 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174650 YP_001221889.1 CDS CMM_1148 NC_009480.1 1313187 1313981 D conserved hypothetical protein (NP_865622.1| conserved hypothetical protein [Pirellula sp. 1]; ZP_00117918.1| COG1305: Transglutaminase-like enzymes,putative cysteine proteases [Cytophaga hutchinsonii]). pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function.; Family membership; hypothetical protein 1313187..1313981 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173558 YP_001221890.1 CDS CMM_1149 NC_009480.1 1314009 1314656 R hypothetical protein TIGR00426: competence protein ComEA helix; hypothetical protein complement(1314009..1314656) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174653 YP_001221891.1 CDS argS NC_009480.1 1314856 1316520 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1314856..1316520 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175073 YP_001221892.1 CDS CMM_1151 NC_009480.1 1316632 1317363 D hypothetical protein (YP_061720.1| hypothetical protein Lxx06820 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825215.1| hypothetical protein SAV4038 [Streptomyces avermitilis MA-4680]).; hypothetical protein 1316632..1317363 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173694 YP_001221893.1 CDS lysA NC_009480.1 1317520 1319019 D Diaminopimelate decarboxylase (DAP decarboxylase)(YP_061724.1| diaminopimelate decarboxylase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228463.1| COG0019: Diaminopimelate decarboxylase [Kineococcus radiotolerans SRS30216]). pfam02784, Orn_Arg_deC_N,Pyridoxal-dependent decarboxylase, pyridoxal binding domain. pfam00278, Orn_DAP_Arg_deC, Pyridoxal-dependent decarboxylase, C-terminal sheet domain.; High confidence in function and specificity; hypothetical protein 1317520..1319019 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175251 YP_001221894.1 CDS thrA NC_009480.1 1319016 1320347 D catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1319016..1320347 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174594 YP_001221895.1 CDS thrC NC_009480.1 1320347 1321423 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1320347..1321423 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174679 YP_001221896.1 CDS thrB NC_009480.1 1321435 1322385 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1321435..1322385 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174857 YP_001221897.1 CDS CMM_1156 NC_009480.1 1322682 1325153 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1322682..1325153 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173268 YP_001221898.1 CDS prfA NC_009480.1 1325159 1326238 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1325159..1326238 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174167 YP_001221899.1 CDS CMM_1158 NC_009480.1 1326263 1327138 D putative methylase of peptide chain release factors (YP_061731.1| methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824087.1| putative methyltransferase [Streptomyces avermitilis MA-4680]). TIGRFam: hemK_fam: modification methylase HemK; Function unclear; putative methylase of peptide chain release factors 1326263..1327138 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173923 YP_001221900.1 CDS CMM_1159 NC_009480.1 1327166 1327819 R putative hydrolase/phosphatase (ZP_00167336.1| COG1011: Predicted hydrolase (HAD superfamily) [Ralstonia eutropha JMP134]; NP_671096.1| putative phosphatase [Yersinia pestis KIM]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase.; Family membership; hypothetical protein complement(1327166..1327819) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175221 YP_001221901.1 CDS CMM_1160 NC_009480.1 1327903 1328832 D conserved hypothetical protein (ZP_00228471.1| COG0009: Putative translation factor (SUA5) [Kineococcus radiotolerans SRS30216]; NP_824086.1| hypothetical protein SAV2910 [Streptomyces avermitilis MA-4680]). pfam01300, Sua5_yciO_yrdC, yrdC domain. This domain has been shown to preferentially bind to dsRNA. The domain is found in SUA5 as well as HypF and YrdC.; hypothetical protein 1327903..1328832 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175901 YP_001221902.1 CDS rfeA NC_009480.1 1328829 1330148 D putative undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (YP_061734.1| undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824083.1| putative teichoic acid linkage unit synthesis (synthesis of undecaprenylpyrophosphate-N-aetylglucosamine), Streptomyces avermitilis MA-4680). pfam00953, Glycos_transf_4, Glycosyl transferase InterPro: Glycosyl transferase family 4; Function unclear; putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 1328829..1330148 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174450 YP_001221903.1 CDS CMM_1162 NC_009480.1 1330145 1330615 D conserved membrane protein (YP_061735.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_737918.1| hypothetical protein [Corynebacterium efficiens YS-314]). eventually involved in ATP synthesis (weak similarity to AtpI); Function unclear; hypothetical protein 1330145..1330615 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174353 YP_001221904.1 CDS atpB NC_009480.1 1330770 1331618 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1330770..1331618 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175770 YP_001221905.1 CDS atpE NC_009480.1 1331665 1331898 D ATP synthase C chain (Lipid-binding protein) (YP_061737.1| ATP synthase, C chain [Leifsonia xyli subsp. xyli str. CTCB07]; AAS68133.1| ATP synthase C subunit [Bifidobacterium animalis]). THIS IS ONE OF THE THREE CHAINS OF THE NONENZYMATIC COMPONENT (CF(0) SUBUNIT) OF THE ATPASE COMPLEX. pfam00137, ATP-synt_C, ATP synthase subunit C.; High confidence in function and specificity; ATP synthase subunit C 1331665..1331898 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174416 YP_001221906.1 CDS atpF NC_009480.1 1331910 1332476 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1331910..1332476 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174260 YP_001221907.1 CDS atpH NC_009480.1 1332476 1333267 D produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1332476..1333267 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175816 YP_001221908.1 CDS atpA NC_009480.1 1333323 1334960 D produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1333323..1334960 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173925 YP_001221909.1 CDS atpG NC_009480.1 1335010 1335909 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1335010..1335909 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174489 YP_001221910.1 CDS atpD NC_009480.1 1335945 1337405 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1335945..1337405 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173321 YP_001221911.1 CDS atpC NC_009480.1 1337407 1337676 D produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon 1337407..1337676 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174537 YP_001221912.1 CDS CMM_1171 NC_009480.1 1337796 1338551 D conserved hypothetical protein (YP_061745.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_738499.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam03883, DUF328,Protein of unknown function (DUF328). Members of this family are functionally uncharacterised.; hypothetical protein 1337796..1338551 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174397 YP_001221913.1 CDS tag NC_009480.1 1338564 1339157 R putative DNA-3-methyladenine glycosylase I (3-methyladenine-DNA glycosylase I constitutive) (YP_061746.1| DNA-3-methyladenine glycosydase I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629291.1| DNA-3-methyladenine glycosylase I [Streptomyces coelicolor A3(2)]). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. pfam03352, Adenine_glyco,Methyladenine glycosylase. The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA. tag: DNA-3-methyladenine glycosylase I; High confidence in function and specificity; putative DNA-3-methyladenine glycosylase I complement(1338564..1339157) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173715 YP_001221914.1 CDS ogtB NC_009480.1 1339154 1339618 R putative methylated-DNA--protein-cysteine methyltransferase (6-O- methylguanine-DNA methyltransferase) (YP_061747.1| methylated-DNA- protein-cysteine S-methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00267484.1| COG0350: Methylated DNA-protein cysteine methyltransferase [Pseudomonas fluorescens PfO-1]). pfam02870, Methyltransf_1N, 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain. pfam01035, Methyltransf_1, 6-O-methylguanine DNA methyltransferase, DNA binding domain.; High confidence in function and specificity; putative methylated-DNA--protein-cysteine methyltransferase complement(1339154..1339618) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175762 YP_001221915.1 CDS CMM_1174 NC_009480.1 1339881 1340360 R transcriptional regulatory protein, AsnC family (NP_823787.1| putative AsnC-family transcriptional regulator [Streptomyces avermitilis MA-4680]; ZP_00059068.1| COG1522: Transcriptional regulators [Thermobifida fusca]). InterPro: Bacterial regulatory proteins AsnC family pfam01037, AsnC_trans_reg, AsnC family. The AsnC family is a family of similar bacterial transcription regulatory proteins.; Specificity unclear; AsnC family transcriptional regulator complement(1339881..1340360) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175643 YP_001221916.1 CDS CMM_1175 NC_009480.1 1340590 1341780 D hypothetical protein containing putative FHA domain (YP_056718.1| hypothetical protein PPA2047 [Propionibacterium acnes KPA171202]).; hypothetical protein 1340590..1341780 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175243 YP_001221917.1 CDS CMM_1176 NC_009480.1 1341777 1342613 D putative protein serine/threonine phosphatase (YP_062154.1| protein phosphatase [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44187.1| protein phosphatase [Tropheryma whipplei str. Twist]). pfam00481, PP2C,Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase. InterPro: Protein phosphatase 2C domain.; Specificity unclear; putative protein serine/threonine phosphatase 1341777..1342613 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174714 YP_001221918.1 CDS dapD NC_009480.1 1342644 1343642 R putative 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase (YP_061899.1| 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226272.1| COG2171: Tetrahydrodipicolinate N-succinyltransferase [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase complement(1342644..1343642) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175936 YP_001221919.1 CDS dapE NC_009480.1 1343723 1344820 D catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; succinyl-diaminopimelate desuccinylase 1343723..1344820 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174877 YP_001221920.1 CDS CMM_1179 NC_009480.1 1344802 1346034 D conserved membrane protein (YP_061901.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789128.1| putative integral membrane protein [Tropheryma whipplei TW08/27]). mraY: phospho-N-acetylmuramoyl-pentape; Conserved hypothetical protein; hypothetical protein 1344802..1346034 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175801 YP_001221921.1 CDS CMM_1180 NC_009480.1 1346182 1346355 D conserved hypothetical protein (YP_061902.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_301785.1| conserved hypothetical protein [Mycobacterium leprae TN]).; hypothetical protein 1346182..1346355 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174405 YP_001221922.1 CDS CMM_1181 NC_009480.1 1346465 1347097 R putative O-methyltransferase (YP_061903.1| O-methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227539.1| COG4122: Predicted O-methyltransferase [Kineococcus radiotolerans SRS30216]). pfam01596, Methyltransf_3, O-methyltransferase. Members of this family are O-methyltransferases. The family includes catechol o-methyl- transferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production. InterPro: O-methyltransferase (family 3) pts-sorbose: PTS system sorbose subfam; Specificity unclear; putative O-methyltransferase complement(1346465..1347097) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175305 YP_001221923.1 CDS tatB NC_009480.1 1347248 1347622 D putative sec-independent protein translocase protein, twin arginine pathway (ZP_00227544.1| COG1826: Sec-independent protein secretion pathway components [Kineococcus radiotolerans SRS30216]; YP_055357.1| conserved protein, putative twin arginine translocation complex component [Propionibacterium acnes KPA171202]).; High confidence in function and specificity; putative sec-independent protein translocase protein, twin arginine pathway 1347248..1347622 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175967 YP_001221924.1 CDS CMM_1183 NC_009480.1 1347668 1348585 R putative transcriptional regulator, LysR-family (NP_828178.1| putative LysR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; ZP_00226031.1| COG0583: Transcriptional regulator [Kineococcus radiotolerans SRS30216]). pfam00126, HTH_1,Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate, LysR substrate binding domain.; Specificity unclear; LysR family transcriptional regulator complement(1347668..1348585) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175944 YP_001221925.1 CDS CMM_1184 NC_009480.1 1348665 1348823 D hypothetical protein 1348665..1348823 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175820 YP_001221926.1 CDS CMM_1185 NC_009480.1 1348915 1350090 R putative ATP-binding protein (NP_301793.1| MRP-family ATP-binding protein [Mycobacterium leprae TN]; NP_939359.1| Putative ATP-binding protein [Corynebacterium diphtheriae NCTC 13129]). pfam00142, Fer4_NifH, 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family. contains a second N-terminal domain: pfam01883, DUF59,Domain of unknown function DUF59. This family includes prokaryotic proteins of unknown function. InterPro: Domain of unknown function DUF59; Function unclear; putative ATP-binding protein complement(1348915..1350090) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175211 YP_001221927.1 CDS CMM_1186 NC_009480.1 1350080 1350628 R putative membrane protein (YP_061906.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824287.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). pfam06210, DUF1003,Protein of unknown function (DUF1003). This family consists of several hypothetical bacterial proteins of unknown function.; Function unclear; hypothetical protein complement(1350080..1350628) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175345 YP_001221928.1 CDS CMM_1187 NC_009480.1 1350612 1351958 R putative Mg2+ transporter, MgtE family (YP_061907.1| protein containg CBS domains [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789177.1| conserved hypothetical protein [Tropheryma whipplei TW08/27]). ,pfam03448, MgtE_N, MgtE intracellular domain. This domain is found in eubacterial magnesium transporters of the MgtE family pfam01769. This region of similarity is presumed to be an intracellular domain, that may be involved in magnesium binding. , pfam00571, CBS, CBS domain. CBS domains are small intracellular modules of unknown function.; Specificity unclear; Mg2+ transporter complement(1350612..1351958) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174948 YP_001221929.1 CDS CMM_1188 NC_009480.1 1352017 1352685 D conserved membrane protein (YP_061908.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_737795.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; hypothetical protein 1352017..1352685 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174127 YP_001221930.1 CDS pepP2 NC_009480.1 1352714 1354336 R putative Xaa-Pro aminopeptidase (Aminopeptidase P I)(Aminoacylproline aminopeptidase I) (YP_061909.1| aminopeptidase P [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225551.1| COG0006: Xaa-Pro aminopeptidase [Kineococcus radiotolerans SRS30216]). , pfam05195, AMP_N,Aminopeptidase P, N-terminal domain. , pfam00557,Peptidase_M24, metallopeptidase family M24.; High confidence in function and specificity; putative Xaa-Pro aminopeptidase complement(1352714..1354336) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174614 YP_001221931.1 CDS CMM_1190 NC_009480.1 1354385 1355422 R putative membrane protein with hydrolase activity (NP_954765.1| hypothetical protein [Gordonia westfalica]; ZP_00120778.2| hypothetical protein Blon020650 [Bifidobacterium longum DJO10A]; NP_789235.1| putative integral membrane protein (possible nuclease activity)[Tropheryma whipplei TW08/27]). pfam03372,Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling (in C-terminal half of the protein).; Function unclear; putative membrane protein with hydrolase activity complement(1354385..1355422) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175069 YP_001221932.1 CDS CMM_1191 NC_009480.1 1355503 1356378 D putative phosphoesterase (YP_061910.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225549.1| COG0613: Predicted metal-dependent phosphoesterases (PHP family) [Kineococcus radiotolerans SRS30216]). pfam02231, PHP_N, PHP domain N-terminal region. The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain.; Function unclear; hypothetical protein 1355503..1356378 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175497 YP_001221933.1 CDS rhlE NC_009480.1 1356467 1357996 R putative ATP dependant RNA helicase (YP_061912.1| ATP-dependent RNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00057513.1| COG0513: Superfamily II DNA and RNA helicases [Thermobifida fusca]; CAB08305.1| PROBABLE ATP-DEPENDENT RNA HELICASE RHLE [Mycobacterium tuberculosis H37Rv]). pfam00270, DEAD, DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Specificity unclear; putative ATP-dependent RNA helicase complement(1356467..1357996) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175679 YP_001221934.1 CDS CMM_1193 NC_009480.1 1358104 1358865 D conserved hypothetical protein (YP_061913.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629315.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1358104..1358865 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175758 YP_001221935.1 CDS CMM_1194 NC_009480.1 1358947 1359234 R putative membrane protein (YP_061914.1| hypothetical protein Lxx09200 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(1358947..1359234) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174235 YP_001221936.1 CDS CMM_1195 NC_009480.1 1359244 1359468 R conserved hypothetical protein (NP_337832.1| hypothetical protein MT3304 [Mycobacterium tuberculosis CDC1551]; YP_061915.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(1359244..1359468) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174711 YP_001221937.1 CDS uvrD1 NC_009480.1 1359662 1362931 D putative ATP-dependant DNA helicase/nuclease (YP_061916.1| ATP-dependent DNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291865.1| COG0210: Superfamily I DNA and RNA helicases [Thermobifida fusca]). pfam00580, UvrD-helicase, UvrD/REP helicase. The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA. Some members have large insertions near to the carboxy-terminus relative to other members of the family. COG2887, RecB family exonuclease [DNA replication,recombination, and repair] domain at the C-terminus; Specificity unclear; putative ATP-dependent DNA helicase/nuclease 1359662..1362931 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175303 YP_001221938.1 CDS uvrD2 NC_009480.1 1362928 1366203 D putative ATP-dependent DNA helicase (YP_061917.1| ATP-dependent DNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227594.1| COG0210: Superfamily I DNA and RNA helicases [Kineococcus radiotolerans SRS30216]). pfam00580, UvrD-helicase, UvrD/REP helicase. The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA. COG1074, RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair] (C-terminal).; Specificity unclear; putative ATP-dependent DNA helicase 1362928..1366203 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174809 YP_001221939.1 CDS CMM_1198 NC_009480.1 1366116 1367192 R putative phosphotransferase (YP_061918.1| macrolide 2'-phosphotransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227597.1| COG3173: Predicted aminoglycoside phosphotransferase [Kineococcus radiotolerans SRS30216]). pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides. degV: degV family protein; Specificity unclear; putative phosphotransferase complement(1366116..1367192) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173514 YP_001221940.1 CDS CMM_1199 NC_009480.1 1367328 1368281 D putative NTP pyrophosphohydrolase (YP_061919.1| NADH pyrophosphatase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227598.1| COG2816: NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid- binding [Kineococcus radiotolerans SRS30216]). pfam00293, NUDIX, NUDIX domain.; Specificity unclear; putative NTP pyrophosphohydrolase 1367328..1368281 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174766 YP_001221941.1 CDS uvrD3 NC_009480.1 1368292 1370205 D putative ATP-dependent DNA helicase (YP_061920.1| ATP-dependent DNA helicase II [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227601.1| COG0210: Superfamily I DNA and RNA helicases [Kineococcus radiotolerans SRS30216]). pfam00580, UvrD-helicase, UvrD/REP helicase. The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA. InterPro: UvrD/REP helicase.; Specificity unclear; putative ATP-dependent DNA helicase 1368292..1370205 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174330 YP_001221942.1 CDS CMM_1201 NC_009480.1 1370069 1370956 R conserved hypothetical protein (CAA16661.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_939100.1| Conserved hypothetical protein [Corynebacterium diphtheriae NCTC 13129]). bcl-2: Apoptosis regulator; hypothetical protein complement(1370069..1370956) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173941 YP_001221943.1 CDS CMM_1202 NC_009480.1 1371099 1372502 R conserved hypothetical protein (YP_061922.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824237.1| hypothetical protein SAV3061 [Streptomyces avermitilis MA-4680]).; hypothetical protein complement(1371099..1372502) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174447 YP_001221944.1 CDS CMM_1203 NC_009480.1 1372715 1373806 D putative ATP-dependant serine protease protein containing a PDZ domain, family S16 (ZP_00227615.1| COG3480: Predicted secreted protein containing a PDZ domain [Kineococcus radiotolerans SRS30216]; YP_061923.1| secreted protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00595, PDZ, PDZ domain (Also known as DHR or GLGF). PDZ domains are found in diverse signaling proteins. , pfam05362, Lon_C, Lon protease (S16) C-terminal proteolytic domain. The Lon serine proteases must hydrolyse ATP to degrade protein substrates.; Function unclear; ATP-dependent serine protease 1372715..1373806 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175671 YP_001221945.1 CDS CMM_1204 NC_009480.1 1373947 1376898 D conseved membrane protein (YP_061924.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789569.1| putative integral membrane protein [Tropheryma whipplei TW08/27]). TIGR00367: K+-dependent Na+/Ca+ exchan; hypothetical protein 1373947..1376898 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174523 YP_001221946.1 CDS CMM_1205 NC_009480.1 1377208 1377873 R putative peroxiredoxin (NP_624490.1| hypothetical protein SCJ1.03c [Streptomyces coelicolor A3(2)]; ZP_00092626.1| COG1225: Peroxiredoxin [Azotobacter vinelandii]). pfam00578, AhpC-TSA, AhpC/TSA family. This family contains proteins related to alkyl hydroperoxide reductase (AhpC) and thiol specific antioxidant (TSA).; Specificity unclear; putative peroxiredoxin complement(1377208..1377873) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175242 YP_001221947.1 CDS CMM_1206 NC_009480.1 1377992 1379713 R conserved hypothetical protein, putative protein kinase (ZP_00017319.1| hypothetical protein [Chloroflexus aurantiacus]; ZP_00112431.1| COG0661: Predicted unusual protein kinase [Nostoc punctiforme]). , pfam03109, ABC1,ABC1 family.; Function unclear; putative protein kinase complement(1377992..1379713) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174647 YP_001221948.1 CDS CMM_1207 NC_009480.1 1379710 1380282 R putative transcriptional regulator, PadR family (NP_625650.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_959288.1| hypothetical protein MAP0354c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam03551, PadR, Transcriptional regulator PadR-like family.; Specificity unclear; PadR family transcriptional regulator complement(1379710..1380282) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173390 YP_001221949.1 CDS lipA NC_009480.1 1380411 1381406 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(1380411..1381406) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174720 YP_001221950.1 CDS lipB NC_009480.1 1381403 1382104 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(1381403..1382104) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173747 YP_001221951.1 CDS CMM_1210 NC_009480.1 1382208 1383107 D putative siderophore-interacting protein (NP_625898.1| conserved hypothetical protein SCI41.06 [Streptomyces coelicolor A3(2)]; NP_337475.1| siderophore utilization protein [Mycobacterium tuberculosis CDC1551]). pfam04954, SIP, Siderophore-interacting protein.; Specificity unclear; putative siderophore-interacting protein 1382208..1383107 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173817 YP_001221952.1 CDS CMM_1211 NC_009480.1 1383261 1383848 D hypothetical protein 1383261..1383848 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174319 YP_001221953.1 CDS CMM_1212 NC_009480.1 1383874 1384521 D hypothetical protein 1383874..1384521 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174231 YP_001221954.1 CDS CMM_1213 NC_009480.1 1384572 1385234 D conserved membrane protein (YP_051757.1| putative membrane protein [Erwinia carotovora subsp. atroseptica SCRI1043]; ZP_00228341.1| COG1284: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]). pfam02588, DUF161, Uncharacterized BCR, YitT family COG1284. This is probably a bacterial ABC transporter permease (personal obs:Yeats C) (twice).; Function unclear; hypothetical protein 1384572..1385234 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174068 YP_001221955.1 CDS CMM_1214 NC_009480.1 1385245 1385583 R putative membrane protein (AAM35479.1| inner membrane protein [Xanthomonas axonopodis pv. citri str. 306]; ZP_00226239.1| COG1299: Phosphotransferase system,fructose-specific IIC component [Kineococcus radiotolerans SRS30216]). bcl-2: Apoptosis regulator; Hypothetical protein; hypothetical protein complement(1385245..1385583) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173933 YP_001221956.1 CDS CMM_1215 NC_009480.1 1386030 1389488 D hypothetical protein 1386030..1389488 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173719 YP_001221957.1 CDS CMM_1216 NC_009480.1 1389546 1390244 R putative cation efflux protein, CDF family (BAD34981.1| hypothetical protein [Arthrobacter globiformis]; ZP_00227400.1| COG0053: Predicted Co/Zn/Cd cation transporters [Kineococcus radiotolerans SRS30216]). pfam01545, Cation_efflux, Cation efflux family. Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.; Function unclear; CDF family cation efflux protein complement(1389546..1390244) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175032 YP_001221958.1 CDS CMM_1217 NC_009480.1 1390241 1390594 R putative transcriptional regulator, ArsR family (NP_600134.1| predicted arsR family transcriptional regulator [Corynebacterium glutamicum ATCC 13032]; H70757 probable transcription regulator - Mycobacterium tuberculosis (strain H37RV)). pfam01022, HTH_5, Bacterial regulatory protein, arsR family.; Specificity unclear; ArsR family transcriptional regulator complement(1390241..1390594) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174676 YP_001221959.1 CDS CMM_1218 NC_009480.1 1390705 1391142 D putative arsenate reductase (NP_898754.1| putative arsenate reductase (ArsC) [Rhodococcus erythropolis]; CAF21520.1| Low molecular weight phosphotyrosine protein phosphatase [Corynebacterium glutamicum ATCC 13032]). pfam01451, LMWPc, Low molecular weight phosphotyrosine protein phosphatase. InterPro: Low molecular weight phosphotyrosine protein phosphatase.; Function unclear; hypothetical protein 1390705..1391142 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175793 YP_001221960.1 CDS CMM_1219 NC_009480.1 1391174 1391800 R putative transcriptional regulator, TetR family (ZP_00188267.2| COG1309: Transcriptional regulator [Rubrobacter xylanophilus DSM 9941]; G69677 transcription regulator of polyketide synthase operon pksA - Bacillus subtilis). InterPro: Bacterial regulatory proteins TetR family pfam00440, TetR_N, Bacterial regulatory proteins,tetR family.; Specificity unclear; TetR family transcriptional regulator complement(1391174..1391800) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175921 YP_001221961.1 CDS CMM_1220 NC_009480.1 1391878 1393194 D putative carboxylesterase (B69680 para-nitrobenzyl esterase (EC 3.1.1.-) - Bacillus subtilis; AAP03116.1| putative carboxyesterase [Streptomyces griseochromogenes]). pfam00135, COesterase,Carboxylesterase.; Specificity unclear; putative carboxylesterase 1391878..1393194 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175781 YP_001221962.1 CDS CMM_1221 NC_009480.1 1393337 1394131 D hypothetical protein 1393337..1394131 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175952 YP_001221963.1 CDS CMM_1222 NC_009480.1 1394148 1395008 R putative hydrolase (NP_301650.1| putative oxidoreductase [Mycobacterium leprae TN]; NP_627387.1| putative hydrolase [Streptomyces coelicolor A3(2)]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. ispD: 4-diphosphocytidyl-2C-methyl-D-er; Function unclear; putative hydrolase complement(1394148..1395008) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175604 YP_001221964.1 CDS CMM_1223 NC_009480.1 1395005 1395571 R putative acetyltransferase (YP_061542.1| acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826247.1| putative acetyltransferase [Streptomyces avermitilis MA-4680]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(1395005..1395571) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175435 YP_001221965.1 CDS CMM_1224 NC_009480.1 1395742 1395936 D Hypothetical protein; hypothetical protein 1395742..1395936 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175634 YP_001221966.1 CDS CMM_1225 NC_009480.1 1396033 1397793 R putative ATP-dependent RNA helicase (YP_062280.1| ATP-dependent RNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; CAB00899.1| PROBABLE COLD-SHOCK DEAD-BOX PROTEIN A HOMOLOG DEAD (ATP-dependent RNA helicase deaD homolog) [Mycobacterium tuberculosis H37Rv]). Cold-shock DEAD-box protein A homolog (ATP-dependent RNA helicase deaD homolog). Has a helix-destabilizing activity (By similarity). pfam00270, DEAD, DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. pfam00271, Helicase_C, Helicase conserved C-terminal domain. pfam03880, DbpA, DbpA RNA binding domain. This RNA binding domain is found at the C-terminus of a number of DEAD helicase proteins.; Function unclear; putative ATP-dependent RNA helicase complement(1396033..1397793) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175128 YP_001221967.1 CDS CMM_1226 NC_009480.1 1397886 1398641 R Hypothetical protein; hypothetical protein complement(1397886..1398641) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174532 YP_001221968.1 CDS CMM_1227 NC_009480.1 1398721 1399578 R putative methyltransferase (NP_823028.1| hypothetical protein SAV1852 [Streptomyces avermitilis MA-4680]; ZP_00225290.1| COG4106: Trans-aconitate methyltransferase [Kineococcus radiotolerans SRS30216]).; Function unclear; putative methyltransferase complement(1398721..1399578) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174974 YP_001221969.1 CDS CMM_1228 NC_009480.1 1399626 1400255 D putative transcriptional regulator, Cro/CI family (ZP_00210190.1| COG1396: Predicted transcriptional regulators [Magnetospirillum magnetotacticum]; ZP_00225291.2| COG1396: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator 1399626..1400255 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174157 YP_001221970.1 CDS CMM_1229 NC_009480.1 1400252 1401739 R hypothetical membrane protein , pfam03793, PASTA,PASTA domain. This domain is found at the C termini of several Penicillin-binding proteins and bacterial serine/threonine kinases.; Hypothetical protein; hypothetical protein complement(1400252..1401739) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173620 YP_001221971.1 CDS CMM_1230 NC_009480.1 1401878 1402093 R hypothetical protein complement(1401878..1402093) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173505 YP_001221972.1 CDS CMM_1231 NC_009480.1 1402248 1402871 R putative carboxylesterase/phospholipase (ZP_00048910.1| COG0400: Predicted esterase [Magnetospirillum magnetotacticum]; NP_769886.1| bll3246 [Bradyrhizobium japonicum USDA 110]). pfam02230,Abhydrolase_2, Phospholipase/Carboxylesterase. This family consists of both phospholipases and carboxylesterases with broad substrate specificity. InterPro: Phospholipase/Carboxylesterase; Function unclear; putative carboxylesterase/phospholipase complement(1402248..1402871) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174020 YP_001221973.1 CDS CMM_1232 NC_009480.1 1402868 1403845 R putative dioxygenase (NP_769887.1| dioxygenase [Bradyrhizobium japonicum USDA 110]; ZP_00007110.1| COG0346: Lactoylglutathione lyase and related lyases [Rhodobacter sphaeroides]). pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily (twice). InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; putative dioxygenase complement(1402868..1403845) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173429 YP_001221974.1 CDS CMM_1233 NC_009480.1 1403907 1404470 R hypothetical protein complement(1403907..1404470) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173881 YP_001221975.1 CDS CMM_1234 NC_009480.1 1404553 1405680 D Hypothetical protein; hypothetical protein 1404553..1405680 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175421 YP_001221976.1 CDS CMM_1235 NC_009480.1 1405686 1406126 R conserved hypothetical protein (ZP_00186867.2| hypothetical protein Rxyl021934 [Rubrobacter xylanophilus DSM 9941]; YP_062966.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(1405686..1406126) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173327 YP_001221977.1 CDS CMM_1236 NC_009480.1 1406232 1406501 D hypothetical protein 1406232..1406501 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173098 YP_001221978.1 CDS CMM_1237 NC_009480.1 1406568 1407698 D putative NDP-sugar phosphate epimerase (ZP_00126896.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Pseudomonas syringae pv. syringae B728a]; ZP_00227125.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; CAC80137.1| progesterone 5-beta-reductase [Digitalis purpurea]).; Function unclear; putative NDP-sugar phosphate epimerase 1406568..1407698 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173260 YP_001221979.1 CDS CMM_1238 NC_009480.1 1407685 1408923 R conserved membrane protein (ZP_00057288.1| COG2311: Predicted membrane protein [Thermobifida fusca]; CAF20253.1| putative membrane protein [Corynebacterium glutamicum ATCC 13032]). pfam04171, DUF405, Protein of unknown function (DUF405). Predicted to be an integral membrane protein. pfam04235, DUF418, Protein of unknown function (DUF418). Probable integral membrane protein.; Function unclear; hypothetical protein complement(1407685..1408923) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172941 YP_001221980.1 CDS CMM_1239 NC_009480.1 1409053 1409979 D putative multidrug ABC transporter, ATPase component (ZP_00227246.1| COG1131: ABC-type multidrug transport system, ATPase component [Kineococcus radiotolerans SRS30216]; NP_626193.1| putative ABC transporter, ATP-binding subunit [Streptomyces coelicolor A3(2)]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative multidrug ABC transporter ATPase 1409053..1409979 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172952 YP_001221981.1 CDS CMM_1240 NC_009480.1 1409976 1410839 D putative multidrug ABC transporter, permease component (ZP_00227245.1| COG0842: ABC-type multidrug transport system, permease component [Kineococcus radiotolerans SRS30216]; NP_827497.1| putative integral membrane transport protein [Streptomyces avermitilis MA-4680]).; Specificity unclear; putative multidrug ABC transporter permease 1409976..1410839 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175691 YP_001221982.1 CDS CMM_1241 NC_009480.1 1410843 1412144 D putative two-component system, sensor kinase (AAD45902.1| histidine kinase ChrS [Corynebacterium diphtheriae]; YP_061777.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-,and HSP90-like ATPase.; Specificity unclear; putative two-component system, sensor kinase 1410843..1412144 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173526 YP_001221983.1 CDS CMM_1242 NC_009480.1 1412141 1412815 D putative two-component system, response regulator (ZP_00200243.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Rubrobacter xylanophilus DSM 9941]; NP_294711.1| DNA-binding response regulator [Deinococcus radiodurans R1]). cd00156, REC, Signal receiver domain. pfam00196, GerE,Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system, response regulator 1412141..1412815 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173329 YP_001221984.1 CDS CMM_1243 NC_009480.1 1413116 1414258 D putative sugar ABC transporter, substrate-binding protein (NP_244309.1| multiple sugar transport system (multiple sugar-binding protein) [Bacillus halodurans C-125]; AAN25480.1| probable sugar binding protein of ABC transporter for pentoses [Bifidobacterium longum NCC2705]). pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators.; Specificity unclear; putative sugar ABC transporter substrate-binding protein 1413116..1414258 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174040 YP_001221985.1 CDS CMM_1244 NC_009480.1 1414382 1415926 D putative sugar ABC transporter, ATP-binding protein (ZP_00225839.1| COG1129: ABC-type sugar transport system,ATPase component [Kineococcus radiotolerans SRS30216]; NP_626651.1| putative sugar-transport ATP binding protein [Streptomyces coelicolor A3(2)]). pfam00005, ABC_tran, ABC transporter(twice).; Specificity unclear; putative sugar ABC transporter ATP-binding protein 1414382..1415926 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174554 YP_001221986.1 CDS CMM_1245 NC_009480.1 1415923 1417131 D putative sugar ABC transporter, permease component (YP_061240.1| L-arabinose ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00121446.1| COG4214: ABC-type xylose transport system,permease component [Bifidobacterium longum DJO10A]). pfam02653, BPD_transp_2, Branched-chain amino acid transport system / permease component.; Specificity unclear; putative sugar ABC transporter permease 1415923..1417131 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174471 YP_001221987.1 CDS CMM_1246 NC_009480.1 1417252 1417536 D hypothetical protein 1417252..1417536 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174433 YP_001221988.1 CDS sipX NC_009480.1 1417546 1418346 R putative signal peptidase I (Leader peptidase I) (ZP_00293226.1| COG0681: Signal peptidase I [Thermobifida fusca]; AAT59376.1| signal peptidase I [Bacillus thuringiensis serovar konkukian str. 97-27]). pfam00461,Peptidase_S26, Signal peptidase I.; Specificity unclear; putative signal peptidase I complement(1417546..1418346) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175396 YP_001221989.1 CDS CMM_1248 NC_009480.1 1418373 1419275 R hypothetical protein complement(1418373..1419275) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174081 YP_001221990.1 CDS CMM_1249 NC_009480.1 1419272 1419874 R hypothetical secreted protein (only weak similarity to: AAP08264.1| Cell envelope-bound metalloprotease (camelysin) [Bacillus cereus ATCC 14579]; ZP_00293230.1| hypothetical protein Tfus02001419 [Thermobifida fusca]).; hypothetical protein complement(1419272..1419874) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174992 YP_001221991.1 CDS CMM_1250 NC_009480.1 1419971 1420516 R hypothetical secreted protein (NP_737798.1| hypothetical protein [Corynebacterium efficiens YS-314];).; hypothetical protein complement(1419971..1420516) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175905 YP_001221992.1 CDS CMM_1251 NC_009480.1 1420874 1422520 D putative two-component system, sensor histidine kinase (ZP_00200781.1| COG0642: Signal transduction histidine kinase [Exiguobacterium sp. 255-15]; ZP_00236041.1| sensory box histidine kinase PhoR [Bacillus cereus G9241]). smart00388, HisKA, His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal.; Specificity unclear; putative two-component system, sensor histidine kinase 1420874..1422520 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174424 YP_001221993.1 CDS CMM_1252 NC_009480.1 1422657 1424486 D putative choline/glycine/betaine transporter, BCCT family (AAN69228.1| choline/carnitine/betaine transporter family protein [Pseudomonas putida KT2440]; CAB40689.1| putative BCCT family transporter [Streptomyces coelicolor A3(2)]). pfam02028, BCCT, BCCT family transporter. bcct: choline/carnitine/betaine transp; Specificity unclear; BCCT family choline/glycine betaine transporter 1422657..1424486 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174962 YP_001221994.1 CDS CMM_1253 NC_009480.1 1424616 1425632 D putative diacylglycerol kinase (YP_055799.1| conserved protein with diacylglycerol kinase catalytic domain [Propionibacterium acnes KPA171202]; YP_062988.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]).; Function unclear; putative diacylglycerol kinase 1424616..1425632 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174598 YP_001221995.1 CDS CMM_1254 NC_009480.1 1425688 1426866 D putative ATPase (NP_719329.1| conserved hypothetical protein [Shewanella oneidensis MR-1]; ZP_00262873.1| COG4637: Predicted ATPase [Pseudomonas fluorescens PfO-1]).; Function unclear; putative ATPase 1425688..1426866 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174288 YP_001221996.1 CDS CMM_1255 NC_009480.1 1426991 1428094 R putative fatty acid desaturase (NP_631110.1| putative delta fatty acid desaturase [Streptomyces coelicolor A3(2)]; ZP_00190195.3| COG3239: Fatty acid desaturase [Kineococcus radiotolerans SRS30216]) Fatty acid desaturase with both delta-5 and delta-6 activities. May represent a component of the polyunsaturated fatty acid biosynthesis pathway. pfam00487, FA_desaturase, Fatty acid desaturase.; Specificity unclear; putative fatty acid desaturase complement(1426991..1428094) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173422 YP_001221997.1 CDS CMM_1256 NC_009480.1 1428412 1429455 R putative Zn-dependent alcohol dehydrogenase (NP_631415.1| oxidoreductase. [Streptomyces coelicolor A3(2)]; AAN73270.1| (S)-specific alcohol dehydrogenase [Rhodococcus erythropolis]). , pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; putative Zn-dependent alcohol dehydrogenase complement(1428412..1429455) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173864 YP_001221998.1 CDS CMM_1257 NC_009480.1 1429505 1430248 R Hypothetical protein; hypothetical protein complement(1429505..1430248) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173304 YP_001221999.1 CDS CMM_1258 NC_009480.1 1430413 1431060 D conserved hypothetical protein (NP_627213.1| conserved hypothetical protein SCE50.18c [Streptomyces coelicolor A3(2)]; ZP_00225215.2| hypothetical protein Krad06002218 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1430413..1431060 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173359 YP_001222000.1 CDS CMM_1259 NC_009480.1 1431088 1434114 R putative alpha-mannosidase (Alpha-D-mannoside mannohydrolase) (NP_828453.1| putative alpha-mannosidase [Streptomyces avermitilis MA-4680]; YP_056165.1| alpha-mannosidase [Propionibacterium acnes KPA171202]). pfam01074, Glyco_hydro_38, Glycosyl hydrolases family 38.; High confidence in function and specificity; putative alpha-mannosidase complement(1431088..1434114) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173411 YP_001222001.1 CDS CMM_1260 NC_009480.1 1434234 1435142 R putative sugar ABC transporter, permease component (YP_061256.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629566.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease complement(1434234..1435142) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172940 YP_001222002.1 CDS CMM_1261 NC_009480.1 1435145 1436149 R putative sugar ABC transporter, permease component (YP_061255.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228402.1| COG1175: ABC-type sugar transport systems, permease components [Kineococcus radiotolerans SRS30216]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; High confidence in function and specificity; putative sugar ABC transporter permease complement(1435145..1436149) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173985 YP_001222003.1 CDS CMM_1262 NC_009480.1 1436152 1437543 R putative sugar ABC transporter, substrate binding protein (NP_629568.1| putative extracellular solute-binding lipoprotein [Streptomyces coelicolor A3(2)]; ZP_00228401.1| COG1653: ABC-type sugar transport system,periplasmic component [Kineococcus radiotolerans SRS30216]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter substrate binding protein complement(1436152..1437543) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172987 YP_001222004.1 CDS CMM_1263 NC_009480.1 1437721 1438986 R putative transcriptional regulator, Rok family (YP_061254.1| transcriptional regulator, ROK family [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00191333.2| COG1940: Transcriptional regulator/sugar kinase [Kineococcus radiotolerans SRS30216]). pfam00480, ROK, ROK family. ROK_glcA_fam: ROK family protein (puta; Specificity unclear; ROK family transcriptional regulator complement(1437721..1438986) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174265 YP_001222005.1 CDS CMM_1264 NC_009480.1 1439158 1440297 D conserved hypothetical protein (NP_625062.1| hypothetical protein SCF81.18 [Streptomyces coelicolor A3(2)]; ZP_00225772.1| hypothetical protein Krad06004462 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1439158..1440297 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173573 YP_001222006.1 CDS CMM_1265 NC_009480.1 1440294 1440596 D conserved secreted protein (ZP_00238872.1| conserved protein [Bacillus cereus G9241]; ZP_00274962.1| COG3369: Uncharacterized conserved protein [Ralstonia metallidurans CH34]).; Conserved hypothetical protein; hypothetical protein 1440294..1440596 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173892 YP_001222007.1 CDS CMM_1266 NC_009480.1 1440613 1441524 R putative Zn-metalloprotease (NP_959994.1| hypothetical protein MAP1060c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00227674.1| COG2321: Predicted metalloprotease [Kineococcus radiotolerans SRS30216]). pfam04228, Zn_peptidase, Putative neutral zinc metallopeptidase. Members of this family have a predicted zinc binding motif characteristic of neutral zinc metallopeptidases.; Function unclear; putative Zn-metalloprotease complement(1440613..1441524) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173034 YP_001222008.1 CDS CMM_1267 NC_009480.1 1441556 1442185 R putative DNA alkylation repair enzyme (weak similarity; NP_899834.1| DNA alkylation repair enzyme [Chromobacterium violaceum ATCC 12472]; NP_720542.1| DNA alkylation repair enzyme [Streptococcus mutans UA159]). possibly COG4912: Predicted DNA alkylation repair enzyme; Conserved hypothetical protein; putative DNA alkylation repair enzyme complement(1441556..1442185) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175500 YP_001222009.1 CDS CMM_1268 NC_009480.1 1442182 1443195 R putative NAD-dependant epimerase (NP_736669.1| hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00227493.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]). pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Specificity unclear; putative NAD-dependent epimerase complement(1442182..1443195) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173883 YP_001222010.1 CDS CMM_1269 NC_009480.1 1443309 1443824 R conserved hypothetical protein (YP_062270.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00294009.1| hypothetical protein Tfus02000211 [Thermobifida fusca]).; hypothetical protein complement(1443309..1443824) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175142 YP_001222011.1 CDS clpS NC_009480.1 1443821 1444195 R putative ATP-dependent Clp protease adaptor protein (YP_062269.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; Q9S2G5|CLPS_STRCO ATP-dependent Clp protease adaptor protein clpS). pfam02617,ClpS, ATP-dependent Clp protease adaptor protein ClpS. In the bacterial cytosol, ATP-dependent protein degradation is performed by several different chaperone-protease pairs, including ClpAP. ClpS directly influences the ClpAP machine by binding to the N-terminal domain of the chaperone ClpA.; High confidence in function and specificity; putative ATP-dependent Clp protease adaptor protein complement(1443821..1444195) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175304 YP_001222012.1 CDS CMM_1271 NC_009480.1 1444284 1444982 R putative two-component system, response regulator (ZP_00228547.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]; YP_061872.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]). cd00156, REC, Signal receiver domain. pfam00196, GerE, Bacterial regulatory proteins,luxR family.; Specificity unclear; putative two-component system, response regulator complement(1444284..1444982) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174381 YP_001222013.1 CDS CMM_1272 NC_009480.1 1444979 1446223 R putative two-component system sensor kinase (YP_061873.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627597.1| putative two component sensor kinase [Streptomyces coelicolor A3(2)]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase complement(1444979..1446223) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174545 YP_001222014.1 CDS CMM_1273 NC_009480.1 1446319 1447158 R putative ABC transporter, permease component (YP_061874.1| ABC transporter, integral membrane subunit [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198462.2| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). weak similarity to: COG1277, NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only] lspA: lipoprotein signal peptidase; Function unclear; putative ABC transporter permease complement(1446319..1447158) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174669 YP_001222015.1 CDS CMM_1274 NC_009480.1 1447155 1448090 R putative multidrug ABC transporter, ATP-binding protein (YP_061875.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_737963.1| putative transport ATP-binding protein [Corynebacterium efficiens YS-314]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative multidrug ABC transporter ATP-binding protein complement(1447155..1448090) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174890 YP_001222016.1 CDS CMM_1275 NC_009480.1 1448221 1449426 R putative aminotransferase (ZP_00225649.1| COG0436: Aspartate/tyrosine/ aromatic aminotransferase [Kineococcus radiotolerans SRS30216]; NP_825694.1| putative aminotransferase [Streptomyces avermitilis MA-4680]). pfam00155, Aminotran_1_2, Aminotransferase class I and II. InterPro: Aminotransferases class-I; Specificity unclear; putative aminotransferase complement(1448221..1449426) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174146 YP_001222017.1 CDS CMM_1276 NC_009480.1 1449499 1450152 D hypothetical protein (ZP_00228066.1| hypothetical protein Krad06002257 [Kineococcus radiotolerans SRS30216]; NP_629174.1| putative lipoprotein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1449499..1450152 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174147 YP_001222018.1 CDS CMM_1277 NC_009480.1 1450416 1451048 D hypothetical protein (ZP_00188960.2| hypothetical protein Krad06004713 [Kineococcus radiotolerans SRS30216]; NP_789426.1| hypothetical protein [Tropheryma whipplei TW08/27]).; hypothetical protein 1450416..1451048 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175320 YP_001222019.1 CDS CMM_1278 NC_009480.1 1451273 1452808 D putative serine protease (NP_737560.1| putative serine protease, heat shock protein [Corynebacterium efficiens YS-314]; YP_062302.1| serine protease [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089,Trypsin, Trypsin. pfam00595, PDZ, PDZ domain (Also known as DHR or GLGF). PDZ domains are found in diverse signaling proteins. InterPro: Serine proteases trypsin family.; Function unclear; putative serine protease 1451273..1452808 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173858 YP_001222020.1 CDS CMM_1279 NC_009480.1 1452959 1454032 D putative glycosyl transferase (YP_062303.1| glucosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826208.1| putative glycosyl transferase [Streptomyces avermitilis MA-4680]). pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyl transferase 1452959..1454032 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174908 YP_001222021.1 CDS CMM_1280 NC_009480.1 1454029 1454850 D putative transferase, putative phosphatidylglycerophosphate synthase (YP_062304.1| transferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293849.1| COG0558: Phosphatidylglycerophosphate synthase [Thermobifida fusca]).; Specificity unclear; putative transferase phosphatidylglycerophosphate synthase 1454029..1454850 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175866 YP_001222022.1 CDS CMM_1281 NC_009480.1 1454847 1455722 D putative glycosyl transferase (YP_062305.1| glycosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_630828.1| putative glycosyltransferase [Streptomyces coelicolor A3(2)]). pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyltransferase 1454847..1455722 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175570 YP_001222023.1 CDS CMM_1282 NC_009480.1 1455820 1457106 D putative CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase (Polyglycerol phosphate polymerase) (YP_062607.1| teichoic acid synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_267077.1| teichoic acid biosynthesis protein [Lactococcus lactis subsp. lactis Il1403]). pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerisation of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.; Function unclear; putative CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase 1455820..1457106 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175122 YP_001222024.1 CDS CMM_1283 NC_009480.1 1457153 1457902 R conserved membrane protein (YP_062301.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_301803.1| putative membrane protein [Mycobacterium leprae]).; hypothetical protein complement(1457153..1457902) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174565 YP_001222025.1 CDS CMM_1284 NC_009480.1 1458057 1458380 D putative transcriptional regulator, Cro/CI family (CAD12221.1| hypothetical protein [Corynebacterium glutamicum]; AAN62096.1| conserved hypothetical protein [Pseudomonas aeruginosa]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator 1458057..1458380 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174321 YP_001222026.1 CDS CMM_1285 NC_009480.1 1458370 1458681 R hypothetical protein (YP_062300.1| hypothetical protein Lxx13690 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(1458370..1458681) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173910 YP_001222027.1 CDS CMM_1286 NC_009480.1 1458766 1459545 R putative polysaccharide/polyol phosphate ABC transporter, ATP-binding protein (YP_062299.1| lipopolysaccharide exporter [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058569.1| COG1134: ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Thermobifida fusca]). MAYBE INVOLVED IN THE BIOSYNTHESIS OF TEICHOIC ACIDS. pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative polysaccharide/polyol phosphate ABC transporter ATP-binding protein complement(1458766..1459545) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173590 YP_001222028.1 CDS tagG NC_009480.1 1459545 1460345 R putative polysaccharide/polyol phosphate ABC transporter, permease component (YP_062298.1| lipopolysaccharide exporter [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058570.1| COG1682: ABC-type polysaccharide/polyol phosphate export systems, permease component [Thermobifida fusca]). MAYBE INVOLVED IN THE BIOSYNTHESIS OF TEICHOIC ACIDS. pfam01061, ABC2_membrane,ABC-2 type transporter.; Specificity unclear; putative polysaccharide/polyol phosphate ABC transporter permease complement(1459545..1460345) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175198 YP_001222029.1 CDS CMM_1288 NC_009480.1 1460382 1461074 R putative sugar nucleotidyltransferase (ZP_00226670.1| COG1213: Predicted sugar nucleotidyltransferases [Kineococcus radiotolerans SRS30216]; ZP_00058566.1| COG1213: Predicted sugar nucleotidyltransferases [Thermobifida fusca]; NP_810634.1| putative glucose-1-P -cytidylyltransferase [Bacteroides thetaiotaomicron VPI-5482]). MAYBE INVOLVED IN THE BIOSYNTHESIS OF TEICHOIC ACIDS. pfam00483,NTP_transferase, Nucleotidyl transferase. This family includes a wide range of enzymes which transfer nucleotides onto phosphosugars.; Specificity unclear; putative sugar nucleotidyltransferase complement(1460382..1461074) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174500 YP_001222030.1 CDS CMM_1289 NC_009480.1 1462342 1463223 D putative ABC transporter, ATP-binding protein (YP_062297.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; cNP_696828.1| ATP-binding protein of ABC transporter system [Bifidobacterium longum NCC2705]). pfam00005, ABC_tran,ABC transporter.; Specificity unclear; putative ABC transporter ATP-binding protein 1462342..1463223 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175006 YP_001222031.1 CDS CMM_1290 NC_009480.1 1463199 1464770 D conserved membrane protein, putative ABC transporter permease component (YP_062296.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056499.1| ABC transporter associated permease [Propionibacterium acnes KPA171202]).; putative ABC transporter permease 1463199..1464770 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174367 YP_001222032.1 CDS CMM_1291 NC_009480.1 1464824 1465111 D conserved hypothetical protein (YP_062295.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228314.1| hypothetical protein Krad06001616 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1464824..1465111 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174237 YP_001222033.1 CDS pncB NC_009480.1 1465136 1466452 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1465136..1466452) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175843 YP_001222034.1 CDS CMM_1293 NC_009480.1 1466543 1468006 D conserved hypothetical protein (ZP_00228361.1| COG3046: Uncharacterized protein related to deoxyribodipyrimidine photolyase [Kineococcus radiotolerans SRS30216]; NP_624520.1| conserved hypothetical protein SCJ1.33 [Streptomyces coelicolor A3(2)]). pfam04244, DPRP, Deoxyribodipyrimidine photolyase-related protein.; Function unclear; hypothetical protein 1466543..1468006 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173324 YP_001222035.1 CDS murI NC_009480.1 1468065 1468949 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1468065..1468949 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174688 YP_001222036.1 CDS rph NC_009480.1 1468958 1469695 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 1468958..1469695 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175360 YP_001222037.1 CDS CMM_1296 NC_009480.1 1469707 1470315 D putative xanthosine triphosphate pyrophosphatase (YP_062291.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228325.1| COG0127: Xanthosine triphosphate pyrophosphatase [Kineococcus radiotolerans SRS30216]; NP_739010.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). , cd00515, HAM1, NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. TIGR00042: HAM1 protein; Function unclear; putative xanthosine triphosphate pyrophosphatase 1469707..1470315 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172954 YP_001222038.1 CDS czcD NC_009480.1 1470406 1471323 D putative cobalt-zinc-cadmium efflux permease, CDF family (Cation efflux system protein)(YP_063177.1| cobalt-zinc-cadmium efflux permease [Leifsonia xyli subsp. xyli str. CTCB07]; NP_630824.1| putative efflux protein [Streptomyces coelicolor A3(2)]). , pfam01545,Cation_efflux, Cation efflux family. Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium,zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.; High confidence in function and specificity; cobalt-zinc-cadmium efflux permease 1470406..1471323 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174173 YP_001222039.1 CDS CMM_1298 NC_009480.1 1471378 1472106 R conserved membrane protein (YP_062290.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789563.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; NP_940604.1| Putative integral membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam00597, DedA, DedA family. This family combines the DedA related proteins and YIAN/YGIK family. Members of this family are not functionally characterised. These proteins contain multiple predicted transmembrane regions.; Function unclear; hypothetical protein complement(1471378..1472106) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174745 YP_001222040.1 CDS CMM_1299 NC_009480.1 1472374 1473798 D Region start changed from 1472365 to 1472374 (-9 bases); putative xylulose kinase 1472374..1473798 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174275 YP_001222041.1 CDS CMM_1300 NC_009480.1 1473870 1475105 D putative ATPase, type II/type IV pathway secretion protein (AAO44286.1| putative type II/type IV pathway secretion protein [Tropheryma whipplei str. Twist]; ZP_00228298.1| COG4962: Flp pilus assembly protein, ATPase CpaF [Kineococcus radiotolerans SRS30216]). pfam00437,GSPII_E, Type II/IV secretion system protein. This family contains both type II and type IV pathway secretion proteins from bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection.; Function unclear; putative ATPase, type II/type IV pathway secretion protein 1473870..1475105 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174133 YP_001222042.1 CDS CMM_1301 NC_009480.1 1475102 1475965 D conserved membrane protein, putative pilus assembly protein (NP_789510.1| putative membrane protein [Tropheryma whipplei TW08/27]; NP_628691.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam00482, GSPII_F, Bacterial type II secretion system protein F domain.; Function unclear; putative pilus assembly protein 1475102..1475965 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174577 YP_001222043.1 CDS CMM_1302 NC_009480.1 1475962 1476912 D conserved membrane protein, putative pilus assembly protein (NP_789509.1| putative membrane protein [Tropheryma whipplei TW08/27]; ZP_00228300.1| COG2064: Flp pilus assembly protein TadC [Kineococcus radiotolerans SRS30216]). pfam00482, GSPII_F, Bacterial type II secretion system protein F domain.; Function unclear; putative pilus assembly protein 1475962..1476912 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175609 YP_001222044.1 CDS CMM_1303 NC_009480.1 1476963 1477157 D conserved membrane protein (ZP_00228301.1| hypothetical protein Krad06001602 [Kineococcus radiotolerans SRS30216]; NP_789508.1| putative membrane protein [Tropheryma whipplei TW08/27]). may be involved in pilus assembly; hypothetical protein 1476963..1477157 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174449 YP_001222045.1 CDS CMM_1304 NC_009480.1 1477157 1477534 D conserved secreted protein (ZP_00228302.1| hypothetical protein Krad06001603 [Kineococcus radiotolerans SRS30216]; NP_789507.1| putative membrane protein [Tropheryma whipplei TW08/27]). may be involved in pilus assembly only weak similarity to: COG4961, TadG, Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; hypothetical protein 1477157..1477534 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174717 YP_001222046.1 CDS CMM_1305 NC_009480.1 1477509 1477964 D conserved hypothetical protein (ZP_00228303.1| hypothetical protein Krad06001604 [Kineococcus radiotolerans SRS30216]; NP_789506.1| putative membrane/secreted protein [Tropheryma whipplei TW08/27]). may be involved in pilus assembly. only weak similarity to: COG4961, TadG, Flp pilus assembly protein TadG [Intracellular trafficking and secretion].; hypothetical protein 1477509..1477964 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175735 YP_001222047.1 CDS CMM_1306 NC_009480.1 1477961 1478500 D puataive secreted protein (NP_789505.1| putative membrane protein [Tropheryma whipplei TW08/27]). may be involved in pilus assembly.; Hypothetical protein; hypothetical protein 1477961..1478500 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174999 YP_001222048.1 CDS CMM_1307 NC_009480.1 1478508 1479815 R putative MFS permease (CAE40411.1| probable transporter [Bordetella pertussis]; NP_787325.1| multidrug efflux protein [Tropheryma whipplei str. Twist]; ZP_00226080.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS permease complement(1478508..1479815) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173718 YP_001222049.1 CDS prfB NC_009480.1 1479891 1480994 D Peptide chain release factor 2 (RF-2) (YP_062287.1| peptide chain release factor 2 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228305.1| COG1186: Protein chain release factor B [Kineococcus radiotolerans SRS30216]). Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity). pfam00472, RF-1,Peptidyl-tRNA hydrolase domain. This domain is found in peptide chain release factors such as RF-1 and RF-2, and a number of smaller proteins of unknown function. This domain contains the peptidyl-tRNA hydrolase activity. prfB: peptide chain release factor 2.; High confidence in function and specificity; peptide chain release factor RF-2 1479891..1480994 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174630 YP_001222050.1 CDS ftsE NC_009480.1 1481070 1482737 D putative ABC transporter, ATP-binding protein involved in cell division (NP_789501.1| cell division ATP-binding protein FtsE [Tropheryma whipplei TW08/27]). pfam00005, ABC_tran, ABC transporter.; High confidence in function and specificity; putative cell division ABC transporter ATP-binding protein 1481070..1482737 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174531 YP_001222051.1 CDS ftsX NC_009480.1 1482734 1483651 D putative ABC transporter, permease component,involved in cell division (YP_062285.1| cell division protein [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44297.1| cell division protein FtsX [Tropheryma whipplei str. Twist]). pfam02687, FtsX, Predicted permease. This is a family of predicted permeases and hypothetical transmembrane proteins. ftsX: cell division ABC transporter pe; High confidence in function and specificity; putative ABC transporter permease,involved in cell division 1482734..1483651 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173885 YP_001222052.1 CDS smpB NC_009480.1 1483718 1484194 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1483718..1484194 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174190 YP_001222053.1 CDS CMM_1312 NC_009480.1 1484812 1486623 R putative iron ABC transporter, permease component (NP_359235.1| ABC transporter membrane-spanning permease -unknown substrate [Streptococcus pneumoniae R6]; ZP_00313850.1| COG1178: ABC-type Fe3+ transport system,permease component [Clostridium thermocellum ATCC 27405]).; Specificity unclear; putative iron ABC transporter permease complement(1484812..1486623) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175037 YP_001222054.1 CDS CMM_1313 NC_009480.1 1486626 1487654 R putative iron ABC transporter, ATPase component (NP_359236.1| ABC transporter ATP-binding protein -unknown substrate [Streptococcus pneumoniae R6]; ZP_00313849.1| COG3842: ABC-type spermidine/putrescine transport systems, ATPase components [Clostridium thermocellum ATCC 27405]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily; Specificity unclear; putative iron ABC transporter ATPase complement(1486626..1487654) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175036 YP_001222055.1 CDS CMM_1314 NC_009480.1 1487654 1488736 R putative iron ABC transporter, substrate-binding protein (NP_359237.1| ABC transporter substrate-binding protein - unknown substrate [Streptococcus pneumoniae R6]; ZP_00313848.1| COG1840: ABC-type Fe3+ transport system, periplasmic component [Clostridium thermocellum ATCC 27405]).; Specificity unclear; putative iron ABC transporter substrate-binding protein complement(1487654..1488736) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174349 YP_001222056.1 CDS CMM_1315 NC_009480.1 1488976 1490478 D putative MFS-type efflux protein (ZP_00228110.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_733510.1| putative transmembrane efflux protein. [Streptomyces coelicolor A3(2)]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS-type efflux protein 1488976..1490478 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174277 YP_001222057.1 CDS CMM_1316 NC_009480.1 1490510 1491322 R putative monophosphatase (ZP_00227046.1| COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monnophosphatase family [Kineococcus radiotolerans SRS30216]; NP_824226.1| putative monophosphatase [Streptomyces avermitilis MA-4680]). pfam00459, Inositol_P, Inositol monophosphatase family.; Specificity unclear; putative monophosphatase complement(1490510..1491322) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175546 YP_001222058.1 CDS CMM_1317 NC_009480.1 1491333 1492409 R putative GTPase (ZP_00227044.1| COG1162: Predicted GTPases [Kineococcus radiotolerans SRS30216]; CAF19467.1| putative GTPase [Corynebacterium glutamicum ATCC 13032]).; Function unclear; putative GTPase complement(1491333..1492409) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175074 YP_001222059.1 CDS aroA NC_009480.1 1492406 1493869 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(1492406..1493869) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175900 YP_001222060.1 CDS sigH NC_009480.1 1493934 1494758 D RNA polymerase sigma-factor, ECF subfamily (Sigma-24) (NP_962258.1| SigH [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00227040.1| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Kineococcus radiotolerans SRS30216]). ,pfam04542, Sigma70_r2, Sigma-70 region 2. , pfam04545,Sigma70_r4, Sigma-70, region 4.; Specificity unclear; ECF subfamily RNA polymerase sigma factor 1493934..1494758 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173043 YP_001222061.1 CDS rsrA NC_009480.1 1494755 1494997 D putative anti-sigma factor involved in the regulation of oxidative stress, putative regulation of sigH (directly upstream) (NP_939084.1| Putative anti sigma factor [Corynebacterium diphtheriae NCTC13129]; NP_824213.1| putative anti-sigma factor [Streptomyces avermitilis MA-4680]). COG5662, Predicted transmembrane transcriptional regulator [Transcription]; Specificity unclear; putative anti-sigma factor 1494755..1494997 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173920 YP_001222062.1 CDS CMM_1321 NC_009480.1 1495033 1495473 D putative acetyl transferase (AAP83142.1| putative acetyltransferase [Lysobacter enzymogenes]; ZP_00107049.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Nostoc punctiforme]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase; Function unclear; putative acetyl transferase 1495033..1495473 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174859 YP_001222063.1 CDS kgd NC_009480.1 1495574 1499392 R kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; alpha-ketoglutarate decarboxylase complement(1495574..1499392) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174369 YP_001222064.1 CDS guaB3 NC_009480.1 1499573 1501012 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 1499573..1501012 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173727 YP_001222065.1 CDS CMM_1324 NC_009480.1 1501126 1502556 D conserved membrane protein (ZP_00227019.1| COG1253: Hemolysins and related proteins containing CBS domains [Kineococcus radiotolerans SRS30216]; NP_828257.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). pfam01595, DUF21, Domain of unknown function DUF21. This transmembrane region has no known function. pfam00571, CBS, CBS domain. CBS domains are small intracellular modules of unknown function. pfam03471, CorC_HlyC, Transporter associated domain. This small domain is found in a family of proteins with the pfam01595 domain and two CBS domains with this domain found at the C-terminus of the proteins, the domain is also found at the C terminus of some Na+/H+ antiporters.; Function unclear; hypothetical protein 1501126..1502556 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173262 YP_001222066.1 CDS CMM_1325 NC_009480.1 1502549 1503592 D conserved membrane protein (ZP_00227018.1| COG1253: Hemolysins and related proteins containing CBS domains [Kineococcus radiotolerans SRS30216]; NP_828256.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). pfam01595, DUF21, Domain of unknown function DUF21. This transmembrane region has no known function. pfam00571, CBS, CBS domain. CBS domains are small intracellular modules of unknown function.; Function unclear; hypothetical protein 1502549..1503592 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174576 YP_001222067.1 CDS CMM_1326 NC_009480.1 1503662 1504741 R putative NADH-dependent flavin oxidoreductase (AAK73169.1| NADH-dependent flavin oxidoreductase [Brevibacterium sp. HCU]; NP_739487.1| putative NADH-dependent flavin oxidoreductase [Corynebacterium efficiens YS-314]). pfam00724, Oxidored_FMN, NADH:flavin oxidoreductase / NADH oxidase family.InterPro: NADH:flavin oxidoreductase/NADH oxidase; Function unclear; putative oxidoreductase complement(1503662..1504741) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174956 YP_001222068.1 CDS CMM_1327 NC_009480.1 1504825 1505757 D putative sugar kinase (BAA94841.1| hypothetical protein [Arthrobacter sp. Q36]). pfam01256, Carb_kinase,Carbohydrate kinase. InterPro: Uncharacterized protein family UPF0031; Function unclear; hypothetical protein 1504825..1505757 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175212 YP_001222069.1 CDS CMM_1328 NC_009480.1 1505754 1506434 R conserved hypothetical protein (ZP_00227777.1| COG2353: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_939578.1| Putative secreted protein [Corynebacterium diphtheriae NCTC 13129]).; Function unclear; hypothetical protein complement(1505754..1506434) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175759 YP_001222070.1 CDS CMM_1329 NC_009480.1 1506642 1506959 D conserved hypothetical protein (NP_737931.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00228490.1| COG0011: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]). pfam01910, DUF77, Domain of unknown function DUF77. Domain of unknown function.; Function unclear; hypothetical protein 1506642..1506959 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175763 YP_001222071.1 CDS CMM_1330 NC_009480.1 1507035 1508315 D putative MFS permease (NP_384591.1| PUTATIVE TRANSPORT TRANSMEMBRANE PROTEIN [Sinorhizobium meliloti 1021]; YP_046983.1| putative permease (MFS superfamily) [Acinetobacter sp. ADP1]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS permease 1507035..1508315 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175203 YP_001222072.1 CDS CMM_1331 NC_009480.1 1508355 1509011 R putative two-component system response regulator (ZP_00225674.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]; NP_737890.1| putative transcription regulator [Corynebacterium efficiens YS-314]). pfam00196, GerE, Bacterial regulatory proteins, luxR family. pfam00072, Response_reg, Response regulator receiver domain.; Specificity unclear; putative two-component system response regulator complement(1508355..1509011) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174136 YP_001222073.1 CDS CMM_1332 NC_009480.1 1509039 1510271 R putative membrane protein (ZP_01131051.1| hypothetical protein A20C1_00590 [marine actinobacterium PHSC20C1]; AAT89627.1| hypothetical protein Lxx18970 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(1509039..1510271) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173607 YP_001222074.1 CDS CMM_1333 NC_009480.1 1510268 1511422 R putative two-component system sensor kinase (BAB98004.1| Two-component system, sensory transduction histidine kinases [Corynebacterium glutamicum ATCC 13032]; NP_696797.1| possible histidine kinase sensor of two component system [Bifidobacterium longum NCC2705]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-,and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase complement(1510268..1511422) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174164 YP_001222075.1 CDS CMM_1334 NC_009480.1 1511593 1512273 R putative two-component system response regulator (ZP_00225674.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]; NP_737890.1| putative transcription regulator [Corynebacterium efficiens YS-314]). pfam00072, Response_reg, Response regulator receiver domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system response regulator complement(1511593..1512273) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173823 YP_001222076.1 CDS metX NC_009480.1 1512393 1513562 R Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase complement(1512393..1513562) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173731 YP_001222077.1 CDS metY NC_009480.1 1513646 1515016 R catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase complement(1513646..1515016) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173800 YP_001222078.1 CDS CMM_1337 NC_009480.1 1515152 1515949 D putative oxidoreductase/short chain dehydrogenase (NP_630900.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]; NP_601406.1| putative short-chain dehydrogenase [Corynebacterium glutamicum ATCC 13032]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Function unclear; putative oxidoreductase 1515152..1515949 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173225 YP_001222079.1 CDS CMM_1338 NC_009480.1 1515988 1516662 R putative transcriptional regulator, TetR-family (AAK45993.1| transcriptional regulator, TetR family [Mycobacterium tuberculosis CDC1551]; NP_627555.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator complement(1515988..1516662) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175794 YP_001222080.1 CDS CMM_1339 NC_009480.1 1516782 1517852 D putative transporter involved in metal resistance (ZP_00121878.1| COG0861: Membrane protein TerC, possibly involved in tellurium resistance [Bifidobacterium longum DJO10A]; NP_738469.1| putative integral membrane export protein [Corynebacterium efficiens YS-314]). , pfam03741,TerC, Integral membrane protein TerC family.; Function unclear; TerC family integral membrane export protein 1516782..1517852 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175778 YP_001222081.1 CDS CMM_1340 NC_009480.1 1517849 1518670 D putative serine/threonine protein phosphatase (NP_787218.1| protein phosphatase [Tropheryma whipplei str. Twist]; ZP_00024666.1| COG0631: Serine/threonine protein phosphatase [Ralstonia metallidurans]). pfam00481,PP2C, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.; Specificity unclear; putative serine/threonine protein phosphatase 1517849..1518670 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175459 YP_001222082.1 CDS leuC NC_009480.1 1518748 1520217 D dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1518748..1520217 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175377 YP_001222083.1 CDS leuD NC_009480.1 1520220 1520834 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1520220..1520834 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175578 YP_001222084.1 CDS murA NC_009480.1 1520877 1522205 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1520877..1522205 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175404 YP_001222085.1 CDS CMM_1344 NC_009480.1 1522329 1523066 D putative sugar phosphate acyltransferase 1522329..1523066 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174328 YP_001222086.1 CDS gpsA NC_009480.1 1523074 1524126 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1523074..1524126 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175309 YP_001222087.1 CDS ddlC NC_009480.1 1524129 1525238 D D-alanine--D-alanine ligase (D-alanylalanine synthetase) (D-Ala-D-Ala ligase) (NP_629695.1| D-alanine-D-alanine ligase [Streptomyces coelicolor A3(2)]; ZP_00059114.1| COG1181: D-alanine-D-alanine ligase and related ATP-grasp enzymes [Thermobifida fusca]). pfam01820, Dala_Dala_ligas, D-ala D-ala ligase. This family contains D-alanine--D-alanine ligase enzymes EC:6.3.2.4.; High confidence in function and specificity; D-alanine-D-alanine ligase 1524129..1525238 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174346 YP_001222088.1 CDS CMM_1347 NC_009480.1 1525341 1526258 D putative glycosyl transferase (AAK64294.1| unknown [Brevibacterium flavum]; NP_737258.1| putative glycosyl transferase [Corynebacterium efficiens YS-314]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyltransferase 1525341..1526258 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174921 YP_001222089.1 CDS CMM_1348 NC_009480.1 1526215 1526727 R hypothetical protein (NP_789197.1| conserved hypothetical lipoprotein [Tropheryma whipplei TW08/27]; NP_627822.1| putative secreted protein [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(1526215..1526727) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175205 YP_001222090.1 CDS thiL NC_009480.1 1526752 1527837 D thiamine-monophosphate kinase (Thiamine-phosphate kinase)(NP_629697.1| putative thiamine monphosphate kinase [Streptomyces coelicolor A3(2)]; ZP_00059104.1| COG0611: Thiamine monophosphate kinase [Thermobifida fusca]).; High confidence in function and specificity; thiamin-monophosphate kinase 1526752..1527837 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175162 YP_001222091.1 CDS CMM_1350 NC_009480.1 1527834 1528445 R putative DNA methylase (CAF20026.1| N6-adenine-specific methylase [Corynebacterium glutamicum ATCC 13032]; ZP_00228410.1| COG0742: N6-adenine-specific methylase [Kineococcus radiotolerans SRS30216]). pfam03602, Cons_hypoth95, Conserved hypothetical protein 95.; Specificity unclear; putative DNA methylase complement(1527834..1528445) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174120 YP_001222092.1 CDS CMM_1351 NC_009480.1 1528715 1529674 D putative regulatory protein, ATPase (NP_626353.1| putative regulatory protein [Streptomyces coelicolor A3(2)]; ZP_00225463.1| COG0714: MoxR-like ATPases [Kineococcus radiotolerans SRS30216]). pfam00004, AAA,ATPase family associated with various cellular activities (AAA). AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.; Function unclear; putative regulatory protein, ATPase 1528715..1529674 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175111 YP_001222093.1 CDS CMM_1352 NC_009480.1 1529700 1531007 D conserved memebrane protein (NP_626354.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00225464.1| COG1721: Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [Kineococcus radiotolerans SRS30216]). InterPro: Protein of unknown function DUF58 pfam01882, DUF58,Protein of unknown function DUF58.; Function unclear; hypothetical protein 1529700..1531007 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174964 YP_001222094.1 CDS CMM_1353 NC_009480.1 1531004 1533547 D putative membrane-bound protease (NP_626355.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00057749.1| COG1305: Transglutaminase-like enzymes, putative cysteine proteases [Thermobifida fusca]). pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine,and aspartate residues that form the catalytic triad in the structurally characterised transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologues of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.; Function unclear; putative membrane-bound protease 1531004..1533547 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174909 YP_001222095.1 CDS recG NC_009480.1 1533544 1535727 D ATP-dependent DNA helicase recG (ZP_00059102.1| COG1200: RecG-like helicase [Thermobifida fusca]; NP_629701.1| putative ATP-dependent DNA helicase [Streptomyces coelicolor A3(2)]). Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3 to 5 polarity. RecG unwind branched duplex DNA (Y-DNA) (By similarity). InterPro: DEAD/DEAH box helicase pfam00270, DEAD,DEAD/DEAH box helicase. pfam00271, Helicase_C, Helicase conserved C-terminal domain. recG: ATP-dependent DNA helicase RecG; High confidence in function and specificity; ATP-dependent DNA helicase 1533544..1535727 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174898 YP_001222096.1 CDS coaD NC_009480.1 1535754 1536245 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1535754..1536245 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174177 YP_001222097.1 CDS CMM_1356 NC_009480.1 1536265 1536837 D conserved hypothetical protein (ZP_00228407.1| COG1399: Predicted metal-binding, possibly nucleic acid-binding protein [Kineococcus radiotolerans SRS30216]; NP_629705.1| hypothetical protein [Streptomyces coelicolor A3(2)]). pfam02620, DUF177, Uncharacterized ACR, COG1399.; hypothetical protein 1536265..1536837 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173162 YP_001222098.1 CDS rpmF NC_009480.1 1536840 1537043 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1536840..1537043 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174867 YP_001222099.1 CDS rnc NC_009480.1 1537069 1537785 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1537069..1537785 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174840 YP_001222100.1 CDS fpgA NC_009480.1 1537792 1538727 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1537792..1538727 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174850 YP_001222101.1 CDS CMM_1360 NC_009480.1 1538740 1539858 R putative acetyltransferase (NP_822401.1| hypothetical protein SAV1226 [Streptomyces avermitilis MA-4680]; NP_285343.1| hypothetical protein [Deinococcus radiodurans]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions (duplicated). InterPro: GCN5-related N-acetyltransferase; Function unclear; putative acetyltransferase complement(1538740..1539858) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173659 YP_001222102.1 CDS smcA NC_009480.1 1540015 1543770 D putative chromosome segregation ATPase (NP_823834.1| putative chromosome segregation protein [Streptomyces avermitilis MA-4680]; Q9CBT5|SMC_MYCLE Chromosome partition protein smc). PLAYS AN IMPORTANT ROLE IN CHROMOSOME STRUCTURE AND PARTITIONING. ESSENTIAL FOR CHROMOSOME PARTITION (BY SIMILARITY). pfam02463, SMC_N,RecF/RecN/SMC N terminal domain. This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. pfam06470, SMC_hinge, SMC proteins Flexible Hinge Domain. pfam02483, SMC_C, SMC family, C-terminal domain. This Pfam family represents a conserved domain towards the C-terminus of the SMC family proteins.; High confidence in function and specificity; putative chromosome segregation ATPase 1540015..1543770 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174834 YP_001222103.1 CDS ftsY NC_009480.1 1543791 1544666 D Signal recognition particle component (SRP54)(NP_904493.1| signal recognition particle-docking protein FtsY [Porphyromonas gingivalis W83]; ZP_00098684.1| COG0552: Signal recognition particle GTPase [Desulfitobacterium hafniense]). Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). pfam02881, SRP54_N, SRP54-type protein, helical bundle domain. pfam00448, SRP54,SRP54-type protein, GTPase domain. This family includes relatives of the G-domain of the SRP54 family of proteins. InterPro: Cell division transporter substrate-binding protein FtsY; High confidence in function and specificity; signal recognition particle protein 1543791..1544666 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174339 YP_001222104.1 CDS ffhA NC_009480.1 1544729 1546300 D Signal recognition particle protein (srp54) (AAL32278.1| signal recognition particle protein subunit [Arcanobacterium pyogenes]; NP_695507.1| signal recognition particle protein [Bifidobacterium longum NCC2705]; NP_823824.1| putative signal recognition particle [Streptomyces avermitilis MA-4680]). NECESSARY FOR EFFICIENT EXPORT OF EXTRA-CYTOPLASMIC PROTEINS. BINDS TO THE SIGNAL SEQUENCE WHEN IT EMERGES FROM THE RIBOSOMES (BY SIMILARITY). pfam00448, SRP54, SRP54-type protein,GTPase domain. This family includes relatives of the G-domain of the SRP54 family of proteins. pfam02978,SRP_SPB, Signal peptide binding domain. pfam02881,SRP54_N, SRP54-type protein, helical bundle domain.; High confidence in function and specificity; signal recognition particle protein 1544729..1546300 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174196 YP_001222105.1 CDS CMM_1364 NC_009480.1 1546445 1546822 D putative lyase (AAL78051.1| ORFC [Saccharopolyspora erythraea]; ZP_00051953.2| COG0346: Lactoylglutathione lyase and related lyases [Magnetospirillum magnetotacticum]; NP_821960.1| hypothetical protein SAV785 [Streptomyces avermitilis MA-4680]). pfam00903,Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; putative lyase 1546445..1546822 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173388 YP_001222106.1 CDS CMM_1365 NC_009480.1 1546832 1548031 R putative membrane-associated serine protease,subfamily S1C (YP_061252.1| serine protease [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00292210.1| COG0265: Trypsin-like serine proteases, typically periplasmic,contain C-terminal PDZ domain [Thermobifida fusca]). contains two domains: N-terminal, pfam02674, Colicin_V,Colicin V production protein. C-terminal, pfam00089,Trypsin, Trypsin. InterPro: Serine proteases trypsin family.; Function unclear; membrane-associated serine protease complement(1546832..1548031) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174767 YP_001222107.1 CDS CMM_1366 NC_009480.1 1548045 1549196 R Region start changed from 1549235 to 1549196 (-39 bases); hypothetical protein complement(1548045..1549196) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174736 YP_001222108.1 CDS rpsP NC_009480.1 1549452 1549865 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1549452..1549865 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174658 YP_001222109.1 CDS CMM_1368 NC_009480.1 1549869 1550105 D putative RNA-binding protein (YP_062402.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198094.1| COG1837: Predicted RNA-binding protein (contains KH domain)[Kineococcus radiotolerans SRS30216]). pfam00013, KH, KH domain. KH motifs can bind RNA in vitro.; Function unclear; hypothetical protein 1549869..1550105 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174312 YP_001222110.1 CDS rimM NC_009480.1 1550137 1550718 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1550137..1550718 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174626 YP_001222111.1 CDS trmD NC_009480.1 1550720 1551406 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1550720..1551406 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173762 YP_001222112.1 CDS mapA1 NC_009480.1 1551426 1552193 R putative methionine aminopeptidase (Peptidase M) (YP_062397.1| methionine aminopeptidase [Leifsonia xyli subsp. xyli str. CTCB07]; AAN25516.1| methionine aminopeptidase [Bifidobacterium longum NCC2705]). Removes the amino-terminal methionine from nascent proteins. pfam00557, Peptidase_M24, metallopeptidase family M24.; High confidence in function and specificity; putative methionine aminopeptidase complement(1551426..1552193) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175443 YP_001222113.1 CDS CMM_1372 NC_009480.1 1552264 1552755 D Hypothetical protein; hypothetical protein 1552264..1552755 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174845 YP_001222114.1 CDS rplS NC_009480.1 1552926 1553270 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1552926..1553270 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174240 YP_001222115.1 CDS lepB NC_009480.1 1553337 1554089 D putative signal peptidase I (Leader peptidase I)(YP_062656.1| signal peptidase I [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225759.1| COG0681: Signal peptidase I [Kineococcus radiotolerans SRS30216]). pfam00461, Peptidase_S26, Signal peptidase I.; Function unclear; putative signal peptidase I 1553337..1554089 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175692 YP_001222116.1 CDS rnhB NC_009480.1 1554089 1554748 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1554089..1554748 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173114 YP_001222117.1 CDS CMM_1376 NC_009480.1 1554822 1555145 D conserved hypothetical protein (YP_062394.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; CAA98339.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; CAF20372.1| putative CTP synthase (UTP-ammonia lyase) [Corynebacterium glutamicum ATCC 13032]).; Function unclear; hypothetical protein 1554822..1555145 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173036 YP_001222118.1 CDS CMM_1377 NC_009480.1 1555257 1555613 D conserved hypothetical protein, putative endonuclease (YP_062393.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629736.1| hypothetical protein [Streptomyces coelicolor A3(2)]; CAA98371.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam02021, UPF0102, Uncharacterised protein family UPF0102. The function of this family is unknown.; hypothetical protein 1555257..1555613 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174178 YP_001222119.1 CDS CMM_1378 NC_009480.1 1555613 1557169 D putative ATP-dependant serine protease (NP_789248.1| conserved hypothetical protein [Tropheryma whipplei TW08/27]; YP_062392.1| competence protein M [Leifsonia xyli subsp. xyli str. CTCB07]). pfam05362,Lon_C, Lon protease (S16) C-terminal proteolytic domain. The Lon serine proteases must hydrolyse ATP to degrade protein substrates. pfam00004, AAA, ATPase family associated with various cellular activities (AAA). (pfam01078, Mg_chelatase, Magnesium chelatase, subunit ChlI. Magnesium-chelatase is a three-component enzyme that catalyses the insertion of Mg2+ into protoporphyrin IX.); Function unclear; putative ATP-dependent serine protease 1555613..1557169 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174174 YP_001222120.1 CDS CMM_1379 NC_009480.1 1557364 1558659 D putative DNA processing protein (YP_062391.1| DNA processing factor [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789249.1| putative DNA processing protein [Tropheryma whipplei TW08/27]). , pfam02481, SMF, SMF family. The SMF family (DNA processing chain A, dprA) are a group of bacterial proteins.; Function unclear; hypothetical protein 1557364..1558659 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174122 YP_001222121.1 CDS xerC NC_009480.1 1558833 1559729 D putative tyrosine recombinase (NP_961892.1| XerC [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_789250.1| putative DNA recombinase [Tropheryma whipplei TW08/27]). pfam02899, Phage_integr_N, Phage integrase, N-terminal SAM-like domain. pfam00589, Phage_integrase,Phage integrase family. Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase are Arg-173, His-289, Arg-292 and Tyr-324.; Specificity unclear; integrase/recombinase 1558833..1559729 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174050 YP_001222122.1 CDS CMM_1381 NC_009480.1 1559800 1560351 R putative metalloprotease, family M23B (NP_696656.1| narrowly conserved hypothetical protein in M23/M37 peptidase family [Bifidobacterium longum NCC2705]; NP_789252.1| hypothetical protein [Tropheryma whipplei TW08/27]). pfam01551, Peptidase_M37, Peptidase family M23/M37. Members of this family are zinc metallopeptidases with a range of specificities. InterPro: Peptidase family M23/M37.; Function unclear; M23B family metallopeptidase complement(1559800..1560351) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174006 YP_001222123.1 CDS CMM_1382 NC_009480.1 1560452 1561927 D putative sugar MFS permease (YP_062390.1| sugar transporter [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198873.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam00083, Sugar_tr, Sugar (and other) transporter. SP: Sugar transporter; Specificity unclear; putative sugar MFS permease 1560452..1561927 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173936 YP_001222124.1 CDS rpsB NC_009480.1 1562166 1563113 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1562166..1563113 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173737 YP_001222125.1 CDS tsf NC_009480.1 1563223 1564050 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1563223..1564050 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175713 YP_001222126.1 CDS pyrH NC_009480.1 1564207 1564923 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1564207..1564923 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175890 YP_001222127.1 CDS frr NC_009480.1 1565037 1565594 D frrA; Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1565037..1565594 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173857 YP_001222128.1 CDS cdsA NC_009480.1 1565595 1566635 D putative phosphatidate cytidylyltransferase (CDP-diacylglycerol synthase) (CTP:phosphatidate cytidylyltransferase) (NP_337459.1| phosphatidate cytidylyltransferase, putative [Mycobacterium tuberculosis CDC1551]; YP_062197.1| phosphatidate cytidylyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam01148,CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases.; Specificity unclear; putative phosphatidate cytidylyltransferase 1565595..1566635 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173696 YP_001222129.1 CDS CMM_1388 NC_009480.1 1566646 1567191 D conserved hypothetical protein (YP_062198.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789259.1| hypothetical protein [Tropheryma whipplei TW08/27]).; hypothetical protein 1566646..1567191 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173205 YP_001222130.1 CDS CMM_1389 NC_009480.1 1567295 1567999 D conserved secreted protein, putative transglycosylase (YP_062199.1| secreted protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291803.1| COG0741: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Thermobifida fusca]). weak similarity to: pfam01464, SLT,Transglycosylase SLT domain.; Conserved hypothetical protein; hypothetical protein 1567295..1567999 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175295 YP_001222131.1 CDS CMM_1390 NC_009480.1 1568070 1569800 D Putative Na(+)/H(+) antiporter, CPA1 family (YP_061417.1| Na+/H+ antiporter [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00189223.3| COG0025: NhaP-type Na+/H+ and K+/H+ antiporters [Kineococcus radiotolerans SRS30216]). pfam00999, Na_H_Exchanger, Sodium/hydrogen exchanger family. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. TIGRFAM (TIGR00831): Na+/H+ antiporter.; High confidence in function and specificity; CPA1 family Na+/H+ antiporter 1568070..1569800 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174841 YP_001222132.1 CDS CMM_1391 NC_009480.1 1569836 1570132 D putative ATP-/GTP-binding protein (YP_062200.1| ATP/GTP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293982.1| hypothetical protein Tfus02000184 [Thermobifida fusca]).; Conserved hypothetical protein; putative ATP-/GTP-binding protein 1569836..1570132 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174366 YP_001222133.1 CDS CMM_1392 NC_009480.1 1570129 1570863 D conserved hypothetical protein, putative hydrolase (YP_062201.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228488.1| COG2945: Predicted hydrolase of the alpha/beta superfamily [Kineococcus radiotolerans SRS30216]). weak similarity to: pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. gatB: glutamyl-tRNA(Gln) amidotransferas; Function unclear; hypothetical protein 1570129..1570863 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173553 YP_001222134.1 CDS CMM_1393 NC_009480.1 1570892 1571950 R conserved membrane protein, AI-E2 family (NP_789283.1| conserved hypothetical integral membrane protein [Tropheryma whipplei TW08/27]; NP_629892.1| putative membrane protein [Streptomyces coelicolor A3(2)]). , pfam01594, UPF0118, Domain of unknown function DUF20. This transmembrane region is found in putative permeases and predicted transmembrane proteins it has no known function.; Conserved hypothetical protein; AI-E2 family membrane protein complement(1570892..1571950) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174931 YP_001222135.1 CDS CMM_1394 NC_009480.1 1571980 1573755 R conserved hypothetical protein (YP_062203.1| large Ala/Glu-rich protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789284.1| putative low complexity hydrophilic protein [Tropheryma whipplei TW08/27]).; hypothetical protein complement(1571980..1573755) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173347 YP_001222136.1 CDS CMM_1395 NC_009480.1 1574038 1575897 D conserved membrane protein (YP_062204.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787545.1| unknown [Tropheryma whipplei str. Twist]).; hypothetical protein 1574038..1575897 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173453 YP_001222137.1 CDS CMM_1396 NC_009480.1 1575894 1576898 D putative thioredoxin (YP_062205.1| thioredoxin [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055812.1| putative thioredoxin [Propionibacterium acnes KPA171202]). pfam00085, Thioredoxin, Thioredoxin. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond. cd00189, TPR, Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2) -[ASL]-X(4)-[PKE] is the consensus sequence.; Family membership; putative thioredoxin 1575894..1576898 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174244 YP_001222138.1 CDS glgB NC_009480.1 1576974 1579553 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(1576974..1579553) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174492 YP_001222139.1 CDS CMM_1398 NC_009480.1 1579559 1581697 R putative glycosidase (YP_062207.1| alpha-amylase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228507.1| COG0366: Glycosidases [Kineococcus radiotolerans SRS30216]). , pfam00128, Alpha-amylase, Alpha amylase,catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases.; Specificity unclear; putative glycosidase complement(1579559..1581697) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175558 YP_001222140.1 CDS glgP NC_009480.1 1582236 1584791 D putative glucan phosphorylase (NP_733664.1| putative glycogen phosphorylase [Streptomyces coelicolor A3(2)]; ZP_00228508.1| COG0058: Glucan phosphorylase [Kineococcus radiotolerans SRS30216]). pfam00343,Phosphorylase, Carbohydrate phosphorylase. The members of this family catalyse the formation of glucose 1-phosphate from one of the following polyglucoses; glycogen, starch,glucan or maltodextrin.; Specificity unclear; putative glucan phosphorylase 1582236..1584791 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173309 YP_001222141.1 CDS CMM_1400 NC_009480.1 1584831 1586138 R hypothetical secreted protein (ZP_00414486.1| hypothetical protein ArthDRAFT_0607 [Arthrobacter sp. FB24]).; hypothetical protein complement(1584831..1586138) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175834 YP_001222142.1 CDS glgX NC_009480.1 1586295 1588373 R putative glycosyl hydrolase (ZP_00228514.1| COG1523: Type II secretory pathway, pullulanase PulA and related glycosidases [Kineococcus radiotolerans SRS30216]; YP_055821.1| putative glycogen debranching enzyme [Propionibacterium acnes KPA171202]). pfam02922,Isoamylase_N, Isoamylase N-terminal domain. This domain is found in a range of enzymes that act on branched substrates - isoamylase, pullulanase and branching enzyme. pfam00128, Alpha-amylase, Alpha amylase, catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases. InterPro: Glycoside hydrolase family 13; Specificity unclear; putative glycosyl hydrolase complement(1586295..1588373) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174498 YP_001222143.1 CDS csdA NC_009480.1 1588372 1589577 D putative cysteine desulfurase (NP_629622.1| putative pyridoxal-phosphate-dependent aminotransferase [Streptomyces coelicolor A3(2)]; YP_062359.1| cysteine desulfurase [Leifsonia xyli subsp. xyli str. CTCB07]). Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). pfam00266, Aminotran_5,Aminotransferase class-V. InterPro: Aminotransferase class-V; Specificity unclear; putative cysteine desulfurase 1588372..1589577 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173004 YP_001222144.1 CDS mnmA NC_009480.1 1589574 1590737 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1589574..1590737 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173906 YP_001222145.1 CDS ligA NC_009480.1 1590745 1593306 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1590745..1593306 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174763 YP_001222146.1 CDS CMM_1405 NC_009480.1 1593419 1594801 D conserved secreted protein (YP_062355.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626621.1| putative secreted protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1593419..1594801 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174095 YP_001222147.1 CDS CMM_1406 NC_009480.1 1594813 1595268 R putative secreted protein (NP_716552.1| conserved hypothetical protein [Shewanella oneidensis MR-1]). pfam03724, META, Domain of unknown function (306). Small domain family found in proteins of of unknown function.; hypothetical protein complement(1594813..1595268) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173507 YP_001222148.1 CDS gatC NC_009480.1 1595316 1595684 D putative glutamyl-tRNA(Gln) amidotransferase subunit C (Glu-ADT subunit C) (YP_062354.1| glutamyl-tRNA amidotransferase subunit C [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228527.1| COG0721: Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit [Kineococcus radiotolerans SRS30216]). pfam02686, Glu-tRNAGln, Glu-tRNAGln amidotransferase C subunit. This is a family of Glu-tRNAGln amidotransferase C subunits. The Glu-tRNA Gln amidotransferase enzyme itself is an important translational fidelity mechanism replacing incorrectly charged Glu-tRNAGln with the correct Gln-tRANGln via transmidation of the misacylated Glu-tRNAGln. This activity supplements the lack of glutaminyl-tRNA synthetase activity in gram-positive eubacterteria,cyanobacteria, Archaea, and organelles. InterPro: Glutamyl-tRNA(Gln) amidotransferase C subunit TIGRFam: gatC: glutamyl-tRNA(Gln) amidotransferase; High confidence in function and specificity; glutamyl-tRNA(Gln) amidotransferase subunit C 1595316..1595684 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173000 YP_001222149.1 CDS gatA NC_009480.1 1595692 1597239 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1595692..1597239 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175120 YP_001222150.1 CDS gatB NC_009480.1 1597239 1598741 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1597239..1598741 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175016 YP_001222151.1 CDS CMM_1410 NC_009480.1 1598738 1600375 D putative ABC transporter ATP-binding protein (CAF19765.1| ATPase component of ABC transporters with duplicated ATPase domains [Corynebacterium glutamicum ATCC 13032]; NP_630815.1| putative ABC transporter [Streptomyces coelicolor A3(2)]). pfam00005, ABC_tran, ABC transporter (2 times). InterPro: AAA ATPase superfamily.; Function unclear; putative ABC transporter ATP-binding protein 1598738..1600375 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175038 YP_001222152.1 CDS CMM_1411 NC_009480.1 1600400 1602049 R putative secreted protein (CAF19985.1| conserved hypothetical protein [Corynebacterium glutamicum ATCC 13032]). Mtu_fam_11: Mycobacterium tuberculosis; hypothetical protein complement(1600400..1602049) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175809 YP_001222153.1 CDS CMM_1412 NC_009480.1 1602196 1602912 D conserved membrane protein (ZP_00226283.1| COG0586: Uncharacterized membrane-associated protein [Kineococcus radiotolerans SRS30216]; NP_737534.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam00597, DedA, DedA family. This family combines the DedA related proteins and YIAN/YGIK family. Members of this family are not functionally characterised. InterPro: DedA family TIGR00367: K+-dependent Na+/Ca+ exchanger; Function unclear; hypothetical protein 1602196..1602912 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175665 YP_001222154.1 CDS CMM_1413 NC_009480.1 1603039 1603707 D conserved hypothetical protein (YP_061421.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227520.1| hypothetical protein Krad06003909 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1603039..1603707 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175973 YP_001222155.1 CDS CMM_1414 NC_009480.1 1603756 1605444 R activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(1603756..1605444) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175917 YP_001222156.1 CDS CMM_1415 NC_009480.1 1605541 1605987 R conserved hypothetical protein (NP_960888.1| hypothetical protein MAP1954c [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_631754.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(1605541..1605987) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174988 YP_001222157.1 CDS CMM_1416 NC_009480.1 1606061 1607509 R putative dehydrogenase (YP_062999.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_961968.1| hypothetical protein MAP3034 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase. This family consists of various amine oxidases, including maze polyamine oxidase (PAO) and various flavin containing monoamine oxidases (MAO).; Specificity unclear; putative dehydrogenase complement(1606061..1607509) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175296 YP_001222158.1 CDS CMM_1417 NC_009480.1 1607519 1608517 R putative short-chain dehydrogenase (ZP_00228984.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; ZP_00107839.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Nostoc punctiforme]; CAB76332.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]). pfam00106, adh_short,short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Function unclear; short chain dehydrogenase complement(1607519..1608517) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173355 YP_001222159.1 CDS CMM_1418 NC_009480.1 1608615 1610303 R activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(1608615..1610303) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175302 YP_001222160.1 CDS CMM_1419 NC_009480.1 1610368 1611297 R putative short chain dehydrogenase/oxidoreductase (NP_336791.1| oxidoreductase, short-chain dehydrogenase/reductase family [Mycobacterium tuberculosis CDC1551]; NP_535663.1| dehydrogenase [Agrobacterium tumefaciens str. C58]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase complement(1610368..1611297) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175560 YP_001222161.1 CDS argE NC_009480.1 1611781 1612998 D putative acetylornithine deacetylase (EAA64290.1| hypothetical protein AN1583.2 [Aspergillus nidulans FGSC A4]; ZP_00128135.1| COG0624: Acetylornithine deacetylase/ Succinyl-diaminopimelate desuccinylase and related deacylases [Pseudomonas syringae pv. syringae B728a]).,pfam01546, Peptidase_M20, Peptidase family M20/M25/M40. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification.; Specificity unclear; putative acetylornithine deacetylase 1611781..1612998 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173446 YP_001222162.1 CDS CMM_1421 NC_009480.1 1612995 1613486 R conserved hypothetical protein, putative phosphoesterase (NP_828681.1| hypothetical protein SAV7505 [Streptomyces avermitilis MA-4680]; NP_302694.1| conserved hypotehical protein [Mycobacterium leprae TN]). InterPro: Uncharacterized protein family UPF0025 TIGR00040: conserved hypothetical protein; Function unclear; putative phosphoesterase complement(1612995..1613486) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174666 YP_001222163.1 CDS CMM_1422 NC_009480.1 1613567 1614100 D putative acetyltransferase (NP_102782.1| hypothetical protein mlr1123 [Mesorhizobium loti MAFF303099]; NP_422206.1| acetyltransferase, GNAT family [Caulobacter crescentus CB15]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. TIGR00729: ribonuclease HII; Function unclear; putative acetyltransferase 1613567..1614100 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174564 YP_001222164.1 CDS CMM_1423 NC_009480.1 1614159 1614773 D putative sulfite oxidase (NP_822473.1| hypothetical protein SAV1298 [Streptomyces avermitilis MA-4680]; ZP_00051501.1| COG2041: Sulfite oxidase and related enzymes [Magnetospirillum magnetotacticum]). pfam00174,Oxidored_molyb, Oxidoreductase molybdopterin binding domain. This domain is found in a variety of oxidoreductases.; Function unclear; putative sulfite oxidase 1614159..1614773 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174816 YP_001222165.1 CDS CMM_1424 NC_009480.1 1614770 1615516 D Region start changed from 1614740 to 1614770 (-30 bases); putative oxidoreductase 1614770..1615516 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175253 YP_001222166.1 CDS CMM_1425 NC_009480.1 1615581 1616114 D conserved hypothetical protein (AAT89246.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. , CTCB07]; ZP_01090609.1| hypothetical protein DSM3645_12896 [Blastopirellula marina DSM 3645]); hypothetical protein 1615581..1616114 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175113 YP_001222167.1 CDS CMM_1426 NC_009480.1 1616230 1617228 D conserved hypothetical protein (ZP_00198062.1| COG3662: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; ZP_00274370.1| COG3662: Uncharacterized protein conserved in bacteria [Ralstonia metallidurans CH34]). menD: 2-succinyl-6-hydroxy-24-cyclohex; hypothetical protein 1616230..1617228 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175106 YP_001222168.1 CDS dinB NC_009480.1 1617311 1618603 D DNA polymerase IV (YP_062348.1| DNA polymerase IV [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225516.1| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair [Kineococcus radiotolerans SRS30216]). Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity). pfam00817, IMS, impB/mucB/samB family. These proteins are involved in UV protection. InterPro: UMUC family (DNA-repair).; High confidence in function and specificity; DNA polymerase IV 1617311..1618603 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174486 YP_001222169.1 CDS CMM_1428 NC_009480.1 1618615 1619118 D putative membrane protein (YP_063067.1| hypothetical protein Lxx23000 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1618615..1619118 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175670 YP_001222170.1 CDS udgA NC_009480.1 1619167 1620480 R UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (ZP_00226352.1| COG1004: Predicted UDP-glucose 6-dehydrogenase [Kineococcus radiotolerans SRS30216]; NP_334746.1| UDP-glucose 6-dehydrogenase [Mycobacterium tuberculosis CDC1551]). pfam03721, UDPG_MGDP_dh_N, UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain. pfam00984, UDPG_MGDP_dh, UDP-glucose/GDP-mannose dehydrogenase family, central domain. pfam03720,UDPG_MGDP_dh_C, UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain. InterPro: UDP-glucose/GDP-mannose dehydrogenase family.; High confidence in function and specificity; UDP-glucose 6-dehydrogenase complement(1619167..1620480) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174957 YP_001222171.1 CDS treZ NC_009480.1 1620650 1622452 R Malto-oligosyltrehalose trehalohydrolase (4- alpha-D-{(1->4)-alpha- D-glucano}trehalose trehalohydrolase) (Q44316|TREZ_ARTSQ Malto-oligosyltrehalose trehalohydrolase (MTHase) 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase) ; Q53238|TREZ_RHIS1 Malto-oligosyltrehalose trehalohydrolase (MTHase) (4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase) (Maltooligosyl trehalose trehalohydrolase)). , pfam02922,Isoamylase_N, Isoamylase N-terminal domain. This domain is found in a range of enzymes that act on branched substrates - isoamylase, pullulanase and branching enzyme. , pfam00128, Alpha-amylase, Alpha amylase, catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases. , InterPro: Glycoside hydrolase family 13.; High confidence in function and specificity; maltooligosyl trehalose trehalohydrolase complement(1620650..1622452) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172960 YP_001222172.1 CDS treY NC_009480.1 1622449 1624800 R Maltooligosyl trehalose synthase ((14)-alpha-D-glucan 1-alpha- D-glucosylmutase) (Q44315|TREY_ARTSQ Maltooligosyl trehalose synthase ((1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase); AAB95368.1| maltooligosyl trehalose synthase [Brevibacterium helvolum]). Catalyzes the conversion of maltooligosaccharide into the non-reducing saccharide maltooligosyl trehalose (alpha-maltooligosyl alpha-D-glucoside) by intramolecular transglycosylation.; High confidence in function and specificity; maltooligosyl trehalose synthase complement(1622449..1624800) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175231 YP_001222173.1 CDS treX NC_009480.1 1624797 1627001 R putative glucan debranching enzyme (BAA94842.1| glycogen debranching enzyme [Arthrobacter sp. Q36]; AAR83844.1| glycogen debranching enzyme [Brevibacterium helvolum]). pfam02922, Isoamylase_N, Isoamylase N-terminal domain. This domain is found in a range of enzymes that act on branched substrates - isoamylase, pullulanase and branching enzyme. pfam00128, Alpha-amylase, Alpha amylase,catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases.; High confidence in function and specificity; putative glucan debranching enzyme complement(1624797..1627001) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175895 YP_001222174.1 CDS CMM_1433 NC_009480.1 1627212 1627544 D conserved hypothetical protein (YP_062346.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_782141.1| conserved protein [Clostridium tetani E88]; NP_831863.1| hypothetical protein [Bacillus cereus ATCC 14579]).; Function unclear; hypothetical protein 1627212..1627544 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175878 YP_001222175.1 CDS CMM_1434 NC_009480.1 1627819 1628481 D putative ABC-type transporter, permease component (NP_737744.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00120538.2| COG4721: Predicted membrane protein [Bifidobacterium longum DJO10A]; YP_062345.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]).; Function unclear; putative ABC-type transporter, permease 1627819..1628481 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175883 YP_001222176.1 CDS CMM_1435 NC_009480.1 1628484 1630046 D putative ABC transporter, ATP-binding protein (ZP_00120537.1| COG1122: ABC-type cobalt transport system,ATPase component [Bifidobacterium longum DJO10A]; YP_062344.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]). cd00267,ABC_ATPase, ABC (ATP-binding cassette) transporter nucleotide-binding domain (duplicated). InterPro: AAA ATPase superfamily; Specificity unclear; putative ABC transporter ATP-binding protein 1628484..1630046 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175194 YP_001222177.1 CDS CMM_1436 NC_009480.1 1630043 1630837 D putative ABC transporter, permease component (YP_062343.1| ABC-type cobalt transport system [Leifsonia xyli subsp. xyli str. CTCB07]; NP_600308.1| ABC-type transporter, permease component [Corynebacterium glutamicum ATCC 13032]). pfam02361, CbiQ, Cobalt transport protein.; Specificity unclear; putative ABC transporter permease 1630043..1630837 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173586 YP_001222178.1 CDS CMM_1437 NC_009480.1 1630827 1631375 D conserved hypothetical protein (YP_062342.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_737747.1| hypothetical protein [Corynebacterium efficiens YS-314]). pfam00485, PRK,Phosphoribulokinase / Uridine kinase family. InterPro: ATP/GTP-binding site motif A (P-loop); Function unclear; hypothetical protein 1630827..1631375 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175013 YP_001222179.1 CDS CMM_1438 NC_009480.1 1631385 1631657 D hypothetical protein (YP_062341.1| Hypothetical protein Lxx14200 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1631385..1631657 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174830 YP_001222180.1 CDS CMM_1439 NC_009480.1 1631752 1632102 R conserved hypothetical protein (ZP_00228025.1| COG3824: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_857503.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97]). pfam06262, DUF1025, Domain of unknown function (DUF1025). Family of bacterial protein with undetermined function.; hypothetical protein complement(1631752..1632102) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173916 YP_001222181.1 CDS ornA NC_009480.1 1632354 1632974 R 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease complement(1632354..1632974) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174406 YP_001222182.1 CDS CMM_1441 NC_009480.1 1633031 1633246 D putative membrane protein (NP_789296.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; NP_629003.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]).; Hypothetical protein; hypothetical protein 1633031..1633246 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175649 YP_001222183.1 CDS CMM_1442 NC_009480.1 1633300 1633611 D Region start changed from 1633243 to 1633300 (-57 bases); putative thioredoxin 1633300..1633611 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174952 YP_001222184.1 CDS nadE NC_009480.1 1633739 1634560 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1633739..1634560 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175262 YP_001222185.1 CDS CMM_1444 NC_009480.1 1634639 1635346 R hypothetical protein (YP_062230.1| hypothetical protein Lxx12850 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787532.1| unknown [Tropheryma whipplei str. Twist]).; hypothetical protein complement(1634639..1635346) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174760 YP_001222186.1 CDS CMM_1445 NC_009480.1 1635428 1635664 R hypothetical protein complement(1635428..1635664) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175199 YP_001222187.1 CDS msrA NC_009480.1 1635835 1636362 D putative peptide methionine sulfoxide reductase (Protein- methionine-S-oxide reductase) (ZP_00301868.1| COG0225: Peptide methionine sulfoxide reductase [Novosphingobium aromaticivorans DSM 12444]; Q9RTB6|MSRA_DEIRA Peptide methionine sulfoxide reductase msrA (Protein-methionine-S-oxide reductase) (Peptide Met(O)reductase)). pfam01625, PMSR, Peptide methionine sulfoxide reductase. This enzyme repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine. msrA: peptide methionine sulfoxide redu; High confidence in function and specificity; putative peptide methionine sulfoxide reductase 1635835..1636362 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174695 YP_001222188.1 CDS CMM_1447 NC_009480.1 1636462 1636692 D hypothetical protein 1636462..1636692 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174051 YP_001222189.1 CDS CMM_1448 NC_009480.1 1636758 1637201 D hypothetical protein 1636758..1637201 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173091 YP_001222190.1 CDS CMM_1449 NC_009480.1 1637198 1637761 D putative transcriptional regulator, MarR-family (NP_627419.1| putative MarR-family transcriptional repressor [Streptomyces coelicolor A3(2)]; NP_824874.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 1637198..1637761 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174912 YP_001222191.1 CDS CMM_1450 NC_009480.1 1637758 1638231 D putative secreted protein (YP_062227.1| hypothetical protein Lxx12820 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789301.1| putative secreted protein [Tropheryma whipplei TW08/27]).; hypothetical protein 1637758..1638231 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174943 YP_001222192.1 CDS CMM_1451 NC_009480.1 1638295 1639977 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 1638295..1639977 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175136 YP_001222193.1 CDS CMM_1452 NC_009480.1 1639982 1640461 D putative thioesterase (ZP_00227872.1| COG0824: Predicted thioesterase [Kineococcus radiotolerans SRS30216]; NP_789303.1| hypothetical protein [Tropheryma whipplei TW08/27]). pfam03061, 4HBT, Thioesterase superfamily. This family contains a wide variety of enzymes, principally thioesterases. InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site.; Function unclear; putative thioesterase 1639982..1640461 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174754 YP_001222194.1 CDS tesB NC_009480.1 1640482 1641387 R putative acyl-coenzyme A thioesterase II (YP_062222.1| acyl-CoA thioesterase II [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227900.1| COG1946: Acyl-CoA thioesterase [Kineococcus radiotolerans SRS30216]). pfam02551, Acyl_CoA_thio, Acyl-CoA thioesterase. This family represents the thioesterase II domain (duplicated). tesB: acyl-CoA thioesterase II; Specificity unclear; putative acyl-CoA thioesterase II complement(1640482..1641387) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173565 YP_001222195.1 CDS CMM_1454 NC_009480.1 1641471 1642166 D conserved hypothetical protein (YP_062221.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826546.1| hypothetical protein SAV5369 [Streptomyces avermitilis MA-4680]).; hypothetical protein 1641471..1642166 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175484 YP_001222196.1 CDS glbO NC_009480.1 1642194 1642589 R hemoglobin-like protein, truncated hemoglobin family (NP_826547.1| putative globin [Streptomyces avermitilis MA-4680]; ZP_00058748.1| COG2346: Truncated hemoglobins [Thermobifida fusca])., , pfam01152,Bac_globin, Bacterial-like globin. This family of heme binding proteins are found mainly in bacteria. However they can also be found in some protozoa and plants as well., COG2346, Truncated hemoglobins.; Function unclear; hemoglobin-like protein complement(1642194..1642589) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173897 YP_001222197.1 CDS CMM_1456 NC_009480.1 1642589 1643908 R conserved membrane protein (YP_061871.1| small-conductance mechanosensitive channel [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625136.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_626892.1| putative membrane protein [Streptomyces coelicolor A3(2)])., , pfam00924, MS_channel,Mechanosensitive ion channel., COG0668, MscS, Small-conductance mechanosensitive channel.; Family membership; hypothetical protein complement(1642589..1643908) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173974 YP_001222198.1 CDS pepN NC_009480.1 1644071 1646614 R Aminopeptidase N (Lysyl aminopeptidase) (Alanine aminopeptidase) (YP_061876.1| aminopeptidase N [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225907.1| COG0308: Aminopeptidase N [Kineococcus radiotolerans SRS30216]). pfam01433, Peptidase_M1, Peptidase family M1. Members of this family are aminopeptidases. InterPro: Aminopeptidase N APN (CD13); High confidence in function and specificity; hypothetical protein complement(1644071..1646614) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174412 YP_001222199.1 CDS CMM_1458 NC_009480.1 1646766 1647392 D conserved hypothetical protein (ZP_00225908.1| hypothetical protein Krad06004249 [Kineococcus radiotolerans SRS30216]; CAA16043.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). weak similarity to: COG3917, NahD, 2-hydroxychromene-2-carboxylate isomerase [Secondary metabolites biosynthesis,transport, and catabolism]; pfam01323, DSBA, DSBA-like thioredoxin domain. This family contains a diverse set of proteins with a thioredoxin-like structure.; hypothetical protein 1646766..1647392 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175131 YP_001222200.1 CDS rpiA NC_009480.1 1647509 1647997 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 1647509..1647997 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175232 YP_001222201.1 CDS mutM NC_009480.1 1648004 1648993 D putative formamidopyrimidine-DNA glycosylase involved in DNA repair (YP_061878.1| DNA glycosylase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787524.1| putative DNA glycosylase [Tropheryma whipplei str. Twist]). pfam01149, Fapy_DNA_glyco, Formamidopyrimidine-DNA glycosylase N-terminal domain. Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidised purines from damaged DNA. pfam06831, H2TH,Formamidopyrimidine-DNA glycosylase H2TH domain.; High confidence in function and specificity; putative formamidopyrimidine-DNA glycosylase involved in DNA repair 1648004..1648993 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173598 YP_001222202.1 CDS dpsA NC_009480.1 1649193 1649678 R putative stress induced DNA-binding protein (YP_061879.1| starvation- induced DNA-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44492.1| stress induced DNA-binding protein [Tropheryma whipplei str. Twist]). pfam00210, Ferritin, Ferritin-like domain. This family contains ferritins and other ferritin-like proteins such as members of the DPS family and bacterioferritins.; Specificity unclear; putative stress induced DNA-binding protein complement(1649193..1649678) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175515 YP_001222203.1 CDS CMM_1462 NC_009480.1 1649831 1655266 R Hypothetical protein; hypothetical protein complement(1649831..1655266) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175475 YP_001222204.1 CDS tig NC_009480.1 1655837 1657291 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1655837..1657291 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174448 YP_001222205.1 CDS clpP NC_009480.1 1657490 1658077 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1657490..1658077 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173340 YP_001222206.1 CDS clpP2 NC_009480.1 1658114 1658794 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1658114..1658794 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174483 YP_001222207.1 CDS CMM_1466 NC_009480.1 1658859 1660001 R putative monooxygenase (ZP_00292953.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Thermobifida fusca]; NP_822383.1| putative monooxygenase [Streptomyces avermitilis MA-4680]). pfam00296, Bac_luciferase,Luciferase-like monooxygenase. InterPro: bacterial luciferase family protein; Function unclear; putative monooxygenase complement(1658859..1660001) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173287 YP_001222208.1 CDS clpX NC_009480.1 1660153 1661433 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1660153..1661433 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175294 YP_001222209.1 CDS dcpA NC_009480.1 1661515 1663578 R putative peptidyl-dipeptidase (Dipeptidyl carboxypeptidase) (AAM40709.1| peptidyl-dipeptidase [Xanthomonas campestris pv. campestris str. ATCC 33913]; ZP_00198809.2| COG0339: Zn-dependent oligopeptidases [Kineococcus radiotolerans SRS30216]). REMOVES DIPEPTIDES FROM THE C-TERMINI OF N-BLOCKED TRIPEPTIDES TETRAPEPTIDES AND LARGER PEPTIDES. pfam01432, Peptidase_M3, Peptidase family M3.; High confidence in function and specificity; putative peptidyl-dipeptidase complement(1661515..1663578) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173979 YP_001222210.1 CDS CMM_1469 NC_009480.1 1663618 1664421 D putative methylase (NP_823056.1| putative methyltransferase-UbiE family [Streptomyces avermitilis MA-4680]; NP_335290.1| methyltransferase, UbiE/COQ5 family [Mycobacterium tuberculosis CDC1551]). InterPro: ubiE/COQ5 methyltransferase; Function unclear; putative methylase 1663618..1664421 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175658 YP_001222211.1 CDS CMM_1470 NC_009480.1 1664434 1664697 R hypothetical protein (YP_061805.1| hypothetical protein Lxx07900 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(1664434..1664697) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175898 YP_001222212.1 CDS CMM_1471 NC_009480.1 1664697 1665149 R putative acetyltransferase, GNAT family (YP_061806.1| acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_107750.1|; Function unclear; GNAT family acetyltransferase complement(1664697..1665149) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175813 YP_001222213.1 CDS valS NC_009480.1 1665146 1667791 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(1665146..1667791) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174088 YP_001222214.1 CDS pckA NC_009480.1 1667927 1669867 R catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP; phosphoenolpyruvate carboxykinase complement(1667927..1669867) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173341 YP_001222215.1 CDS CMM_1474 NC_009480.1 1669979 1671406 D putative transcriptional regulator, Cro/CI family (ZP_00227904.1| COG3800: Predicted transcriptional regulator [Kineococcus radiotolerans SRS30216]; ZP_00057955.1| COG1396: Predicted transcriptional regulators [Thermobifida fusca]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. pfam06114, DUF955,Domain of unknown function (DUF955). Family of bacterial and viral proteins with undetermined function. InterPro: Helix-turn-helix motif.; Specificity unclear; Cro/CI family transcriptional regulator 1669979..1671406 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175535 YP_001222216.1 CDS CMM_1475 NC_009480.1 1671425 1673089 R putative oligopeptide ABC transporter ATP-binding protein, two fused domains (NP_768244.1| ABC transporter ATP-binding protein [Bradyrhizobium japonicum]; ZP_00191786.2| COG1123: ATPase components of various ABC-type transport systems, contain duplicated ATPase [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative oligopeptide ABC transporter ATP-binding protein complement(1671425..1673089) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174935 YP_001222217.1 CDS CMM_1476 NC_009480.1 1673086 1673946 R putative oligopeptide ABC transporter, permease component (ZP_00228687.1| COG1173: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Kineococcus radiotolerans SRS30216]; NP_768243.1| ABC transporter permease protein [Bradyrhizobium japonicum]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.; Specificity unclear; putative oligopeptide ABC transporter permease complement(1673086..1673946) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174400 YP_001222218.1 CDS CMM_1477 NC_009480.1 1673943 1675013 R putative oligopeptide ABC transporter, permease component (ZP_00228686.1| COG0601: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Kineococcus radiotolerans SRS30216]; NP_641209.1| ABC transporter permease [Xanthomonas axonopodis pv. citri str. 306]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative oligopeptide ABC transporter permease complement(1673943..1675013) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174082 YP_001222219.1 CDS CMM_1478 NC_009480.1 1675010 1676656 R putative oligopeptide ABC transporter, substrate-binding protein (NP_641208.1| ABC transporter oligopeptide binding protein [Xanthomonas axonopodis pv. citri str. 306]; ZP_00191783.2| COG0747: ABC-type dipeptide transport system, periplasmic component [Kineococcus radiotolerans SRS30216]). pfam00496, SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5. InterPro: Bacterial extracellular solute-binding protein family 5.; Specificity unclear; putative oligopeptide ABC transporter substrate-binding protein complement(1675010..1676656) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175915 YP_001222220.1 CDS CMM_1479 NC_009480.1 1676761 1677366 D putative transcriptional regulator, TetR family (ZP_00189647.3| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_518756.1| PROBABLE TRANSCRIPTION REGULATOR PROTEIN [Ralstonia solanacearum GMI1000]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 1676761..1677366 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173733 YP_001222221.1 CDS expA NC_009480.1 1677476 1678237 D putative expansin (AAK16222.1| cellulase CelA [Clavibacter michiganensis subsp. sepedonicus]; XP_367645.1| hypothetical protein MG07556.4 [Magnaporthe grisea 70-15]; AAL24497.1| alpha-expansin [Oryza sativa]).; Function unclear; putative expansin 1677476..1678237 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175204 YP_001222222.1 CDS CMM_1481 NC_009480.1 1678314 1679063 D putative SAM-dependant methyltransferase (NP_962393.1| hypothetical protein MAP3459 [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00276697.1| COG0500: SAM-dependent methyltransferases [Ralstonia metallidurans CH34]). InterPro: SAM (and some other nucleotide) binding motif; Specificity unclear; putative SAM-dependent methyltransferase 1678314..1679063 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172994 YP_001222223.1 CDS ileS NC_009480.1 1679310 1682612 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 1679310..1682612 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174668 YP_001222224.1 CDS folC NC_009480.1 1682609 1684183 D folylpolyglutamate synthase (Folylpoly-gamma-glutamate synthetase) (YP_061811.1| folylpolyglutamate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787604.1| folylpolyglutamate synthase; dihydrofolate synthase [Tropheryma whipplei str. Twist]; NP_826629.1| putative folylpolyglutamate synthase [Streptomyces avermitilis MA-4680]). Conversion of folates to polyglutamate derivatives. pfam01225, Mur_ligase, Mur ligase family, catalytic domain. This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. pfam02875, Mur_ligase_C, Mur ligase family,glutamate ligase domain.; High confidence in function and specificity; hypothetical protein 1682609..1684183 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175481 YP_001222225.1 CDS CMM_1484 NC_009480.1 1684180 1684677 D putative membrane protein (YP_061812.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226697.1| hypothetical protein Krad06002845 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1684180..1684677 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173631 YP_001222226.1 CDS ndkA NC_009480.1 1684687 1685106 D putative nucleoside diphosphate kinase (NDP kinase) (Nucleoside-2-P kinase) (YP_061813.1| nucleoside diphosphate kinase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198869.1| COG0105: Nucleoside diphosphate kinase [Kineococcus radiotolerans SRS30216]). smart00562,NDK, These are enzymes that catalyze nonsubstrate specific conversions of nucleoside diphosphates to nucleoside triphosphates. These enzymes play important roles in bacterial growth, signal transduction and pathogenicity. InterPro: Nucleoside diphosphate kinase; High confidence in function and specificity; hypothetical protein 1684687..1685106 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173809 YP_001222227.1 CDS CMM_1486 NC_009480.1 1685168 1685776 R conserved membrane protein (AAS20061.1| conserved hypothetical protein [Arthrobacter aurescens]; ZP_00227045.1| COG4243: Predicted membrane protein [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein complement(1685168..1685776) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174380 YP_001222228.1 CDS CMM_1487 NC_009480.1 1686082 1689102 D putative ribonuclease (YP_061815.1| ribonuclease G [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00292466.1| COG1530: Ribonucleases G and E [Thermobifida fusca]). pfam00575, S1, S1 RNA binding domain. The S1 domain occurs in a wide range of RNA associated proteins. RNaseEG: ribonuclease Rne/Rng family; Function unclear; putative ribonuclease 1686082..1689102 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174570 YP_001222229.1 CDS CMM_1488 NC_009480.1 1689191 1689469 R conserved hypothetical protein (YP_061816.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293669.1| hypothetical protein Tfus02001029 [Thermobifida fusca]).; hypothetical protein complement(1689191..1689469) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175975 YP_001222230.1 CDS rplU NC_009480.1 1689759 1690067 D 50S ribosomal protein L21 (YP_061817.1| 50S ribosomal protein L21 [Leifsonia xyli subsp. xyli str. CTCB07]; CAB03777.1| PROBABLE 50S RIBOSOMAL PROTEIN L21 RPLU [Mycobacterium tuberculosis H37Rv]; NP_940119.1| 50S ribosomal protein L21 [Corynebacterium diphtheriae NCTC 13129]). This protein binds to 23S ribosomal RNA in the presence of protein L20. pfam00829, Ribosomal_L21p,Ribosomal prokaryotic L21 protein.; High confidence in function and specificity; 50S ribosomal protein L21 1689759..1690067 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174828 YP_001222231.1 CDS rpmA NC_009480.1 1690092 1690346 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1690092..1690346 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173819 YP_001222232.1 CDS obgE NC_009480.1 1690466 1692004 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1690466..1692004 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175920 YP_001222233.1 CDS proB NC_009480.1 1692008 1692787 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1692008..1692787 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175636 YP_001222234.1 CDS proA NC_009480.1 1692835 1694133 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1692835..1694133 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175829 YP_001222235.1 CDS CMM_1494 NC_009480.1 1694234 1694449 D hypothetical membrane protein (YP_061822.1| hypothetical protein Lxx08090 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1694234..1694449 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175760 YP_001222236.1 CDS nadD NC_009480.1 1694467 1695069 D transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1694467..1695069 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175208 YP_001222237.1 CDS CMM_1496 NC_009480.1 1695066 1696592 D conserved hypothetical protein (YP_061824.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1695066..1696592 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173714 YP_001222238.1 CDS CMM_1497 NC_009480.1 1696632 1697009 D conserved hypothetical protein (YP_061825.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00197999.1| COG0799: Uncharacterized homolog of plant Iojap protein [Kineococcus radiotolerans SRS30216]). pfam02410, DUF143, Domain of unknown function DUF143. This domain has no known function nor do any of the proteins that possess it.; Function unclear; hypothetical protein 1696632..1697009 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175310 YP_001222239.1 CDS CMM_1498 NC_009480.1 1697041 1697457 D conserved hypothetical protein (NP_952619.1| conserved hypothetical protein [Geobacter sulfurreducens PCA]; NP_282311.1| hypothetical protein Cj1164c [Campylobacter jejuni subsp. jejuni NCTC 11168]).; Function unclear; hypothetical protein 1697041..1697457 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174584 YP_001222240.1 CDS CMM_1499 NC_009480.1 1697691 1698695 R hypothetical protein (only weak similarities to: NP_980009.1| conserved hypothetical protein [Bacillus cereus ATCC 10987]).; hypothetical protein complement(1697691..1698695) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174478 YP_001222241.1 CDS CMM_1500 NC_009480.1 1698747 1699070 D hypothetical protein 1698747..1699070 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174927 YP_001222242.1 CDS CMM_1501 NC_009480.1 1699112 1700116 D putative esterase (YP_061243.1| secreted hydrolase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_631558.1| putative secreted hydrolase [Streptomyces coelicolor A3(2)]). cd00229, SEST, Streptomyces scabies esterase is a causal agent of the potato scab disease. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases. InterPro: GDSL lipolytic enzyme TIGR00365: glutaredoxin-related protein; Function unclear; putative esterase 1699112..1700116 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175022 YP_001222243.1 CDS CMM_1502 NC_009480.1 1700253 1701041 D putative transcriptional regulator, DeoR family (YP_061707.1| transcriptional regulator, DeoR family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_738434.1| putative deoR-family transcriptional regulator [Corynebacterium efficiens YS-314]). pfam00455, DeoR,Bacterial regulatory proteins, deoR family.; Hypothetical protein; DeoR family transcriptional regulator 1700253..1701041 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174162 YP_001222244.1 CDS fruK NC_009480.1 1701038 1702009 D putative 1-phosphofructokinase (YP_061708.1| 1-phosphofructokinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_738438.1| putative 1-phosphofructokinase [Corynebacterium efficiens YS-314]). pfam00294, PfkB, pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases. InterPro: PfkB family of carbohydrate kinases; Specificity unclear; putative 1-phosphofructokinase 1701038..1702009 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175909 YP_001222245.1 CDS fruA NC_009480.1 1702032 1704089 D phosphoenolpyruvate-dependent fructose phosphotransferase system, EIIA, EIIB, EIIC (YP_054858.1| phosphotransferase system [Propionibacterium acnes KPA171202]; YP_061709.1| PTS system, fructose-specific permease, transmembrane protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00359, PTS_EIIA_2,Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. , pfam02379, PTS_IIB_fruc, PTS system,Fructose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). IIB is is phosphorylated by phospho-IIA, before the phosphoryl group is transferred to the sugar substrate. , pfam02378, PTS_EIIC,Phosphotransferase system, EIIC. , InterPro: Phosphotransferase system EIIC fruA: PTS system IIA component fructo; High confidence in function and specificity; phosphoenolpyruvate-dependent fructose phosphotransferase system, EIIA, EIIB, EIIC 1702032..1704089 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173786 YP_001222246.1 CDS fruB NC_009480.1 1704145 1704417 D phosphotransferase system, phosphocarrier protein HPr (ZP_00226194.1| COG1925: Phosphotransferase system,HPr-related proteins [Kineococcus radiotolerans SRS30216]; YP_055065.1| phosphocarrier protein HPr [Propionibacterium acnes KPA171202]). pfam00381, PTS-HPr,PTS HPr component phosphorylation site.; High confidence in function and specificity; phosphotransferase system, phosphocarrier protein HPr 1704145..1704417 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173729 YP_001222247.1 CDS CMM_1506 NC_009480.1 1704492 1706039 R putative short-chain dehydrogenase/oxidoreductase (NP_828433.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]; NP_640936.1| oxidoreductase [Xanthomonas axonopodis pv. citri str. 306]). pfam00106,adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Function unclear; putative short-chain dehydrogenase/oxidoreductase complement(1704492..1706039) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173829 YP_001222248.1 CDS CMM_1506A NC_009480.1 1706121 1706396 R hypothetical protein complement(1706121..1706396) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175726 YP_001222249.1 CDS CMM_1507 NC_009480.1 1706484 1709024 D putative ATP-dependent helicase (NP_822750.1| putative ATP-dependent helicase [Streptomyces avermitilis MA-4680]; ZP_00293629.1| COG4581: Superfamily II RNA helicase [Thermobifida fusca]). pfam00270, DEAD, DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Specificity unclear; putative ATP-dependent helicase 1706484..1709024 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175965 YP_001222250.1 CDS CMM_1508 NC_009480.1 1709021 1709950 D putative short chain dehydrogenase/oxidoreductase (NP_624645.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; CAA17300.1| Possible oxidoreductase [Mycobacterium tuberculosis H37Rv]). pfam00106, adh_short,short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase 1709021..1709950 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175924 YP_001222251.1 CDS hisC1 NC_009480.1 1709966 1711084 R catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase complement(1709966..1711084) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175268 YP_001222252.1 CDS CMM_1510 NC_009480.1 1711169 1712074 D putative hydrolase (ZP_00108734.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Nostoc punctiforme]; NP_295075.1| dihydrolipoamide acetyltransferase-related protein [Deinococcus radiodurans R1]). pfam00561, Abhydrolase_1,alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. InterPro: Alpha/beta hydrolase fold hupD: hydrogenase expression/formation; Function unclear; putative hydrolase 1711169..1712074 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173480 YP_001222253.1 CDS CMM_1511 NC_009480.1 1712142 1712876 D putative hydrolase/acyltransferase (ZP_00227961.1| COG1075: Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [Kineococcus radiotolerans SRS30216]; AAN48022.1| alpha/beta hydrolase fold [Leptospira interrogans serovar lai str. 56601]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. TIGR00253: conserved hypothetical prote; Function unclear; putative hydrolase/acyltransferase 1712142..1712876 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175966 YP_001222254.1 CDS CMM_1512 NC_009480.1 1712908 1714353 D putative efflux MFS permease (YP_061828.1| transmembrane efflux pump [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627842.1| putative transmembrane efflux protein [Streptomyces coelicolor A3(2)]). efflux_EmrB: drug resistance transport; Specificity unclear; putative efflux MFS permease 1712908..1714353 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175447 YP_001222255.1 CDS CMM_1513 NC_009480.1 1714350 1715327 R putative Zn-dependant oxidoreductase (NP_628012.1| putative quinone oxidoreductase [Streptomyces coelicolor A3(2)]; XP_468289.1| putative quinone oxidoreductase [Oryza sativa (japonica cultivar-group)]). pfam00107,ADH_zinc_N, Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily; Function unclear; putative Zn-dependent oxidoreductase complement(1714350..1715327) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175291 YP_001222256.1 CDS CMM_1514 NC_009480.1 1715482 1716048 D conserved hypothetical protein (YP_061830.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227945.1| COG2353: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]). pfam04264, YceI, YceI like family. E. coli YceI is a base-induced periplasmic protein. Its function has not yet been characterised.; Function unclear; hypothetical protein 1715482..1716048 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175882 YP_001222257.1 CDS CMM_1515 NC_009480.1 1716185 1717144 R putative hydrolase/acyltransferase (NP_661840.1| hydrolase, alpha/beta hydrolase fold family [Chlorobium tepidum TLS]; NP_821687.1| putative hydrolase [Streptomyces avermitilis MA-4680]). pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase/acyltransferase complement(1716185..1717144) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175000 YP_001222258.1 CDS CMM_1516 NC_009480.1 1717308 1718240 R putative hydrolase/acyltransferase (ZP_00283301.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Burkholderia fungorum LB400]; NP_822882.1| putative 3-oxoadipate enol-lactone hydrolase [Streptomyces avermitilis MA-4680]). pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase/acyltransferase complement(1717308..1718240) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175790 YP_001222259.1 CDS CMM_1517 NC_009480.1 1718237 1719283 R conserved membrane protein (YP_062173.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789315.1| putative integral membrane protein. [Tropheryma whipplei TW08/27]). TIGR00040: conserved hypothetical prot; Conserved hypothetical protein; hypothetical protein complement(1718237..1719283) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174622 YP_001222260.1 CDS dnaE1 NC_009480.1 1719355 1722777 R DNA polymerase III alpha subunit (ZP_00225627.1| COG0587: DNA polymerase III, alpha subunit [Kineococcus radiotolerans SRS30216]; NP_827731.1| putative DNA polymerase III alpha subunit [Streptomyces avermitilis MA-4680]). DNA POLYMERASE III IS A COMPLEX MULTICHAIN ENZYME RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA. THIS DNA POLYMERASE ALSO EXHIBITS 3 TO 5 EXONUCLEASE ACTIVITY. THE ALPHA CHAIN IS THE DNA POLYMERASE. polc: DNA polymerase III alpha subuni; High confidence in function and specificity; DNA polymerase III subunit alpha complement(1719355..1722777) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174737 YP_001222261.1 CDS zwfA1 NC_009480.1 1722892 1724259 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1722892..1724259 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175517 YP_001222262.1 CDS CMM_1520 NC_009480.1 1724367 1725110 D putative carboxymethylenebutenolidase (EC 3.1.1.45) (Dienelactone hydrolase) (NP_216570.1| hypothetical protein Rv2054 [Mycobacterium tuberculosis H37Rv]; NP_531327.1| carboxymethylenebutenolidase [Agrobacterium tumefaciens str. C58 (U. Washington)] ). pfam01738, DLH,Dienelactone hydrolase family. InterPro: Dienelactone hydrolase.; Function unclear; putative carboxymethylenebutenolidase 1724367..1725110 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174391 YP_001222263.1 CDS CMM_1521 NC_009480.1 1725174 1726481 D putative transcriptional regulator, LytR family (YP_061827.1| transcriptional regulator, LytR family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787856.1| transcriptional regulator [Tropheryma whipplei str. Twist]). pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.; Specificity unclear; LytR family transcriptional regulator 1725174..1726481 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175230 YP_001222264.1 CDS CMM_1522 NC_009480.1 1726516 1727436 R putative transcriptional regulator, LysR family (NP_534506.1| transcriptional regulator, LysR family [Agrobacterium tumefaciens str. C58]; YP_050354.1| LysR-family transcriptional regulator [Erwinia carotovora subsp. atroseptica SCRI1043]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate, LysR substrate binding domain. The structure of this domain is known and is; Specificity unclear; LysR family transcriptional regulator complement(1726516..1727436) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173841 YP_001222265.1 CDS CMM_1523 NC_009480.1 1727505 1728032 D putative acetyltransferase (YP_048512.1| putative acetyltransferase [Erwinia carotovora subsp. atroseptica SCRI1043]; ZP_00217564.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Burkholderia cepacia R18194]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 1727505..1728032 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175040 YP_001222266.1 CDS CMM_1524 NC_009480.1 1728051 1728749 R putative nicotinamide mononucleotide transporter,PnuC family (CAF18632.1| mononucleotide transporter [Corynebacterium glutamicum ATCC 13032]; YP_056127.1| nicotinamide mononucleotide transporter [Propionibacterium acnes KPA171202]). pfam04973, NMN_transporter,Nicotinamide mononucleotide transporter. Members of this family are integral membrane proteins that are involved in transport of nicotinamide mononucleotide.; Specificity unclear; nicotinamide mononucleotide transporter complement(1728051..1728749) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175343 YP_001222267.1 CDS CMM_1525 NC_009480.1 1728886 1729209 R hypothetical protein complement(1728886..1729209) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174180 YP_001222268.1 CDS CMM_1526 NC_009480.1 1729463 1730332 D putative oxidoreductase (NP_301411.1| putative oxidoreductase [Mycobacterium leprae TN]; ZP_00198753.2| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.; Function unclear; putative oxidoreductase 1729463..1730332 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175255 YP_001222269.1 CDS CMM_1527 NC_009480.1 1730403 1731542 R conserved hypothetical protein (YP_062174.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227742.1| COG4850: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; CAF20598.1| ATPase component of ABC transporters with duplicated ATPase domains [Corynebacterium glutamicum ATCC 13032]).; Function unclear; hypothetical protein complement(1730403..1731542) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174919 YP_001222270.1 CDS CMM_1528 NC_009480.1 1731539 1732270 R conserved hypothetical protein (ZP_00189333.2| COG2135: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_629361.1| conserved hypothetical protein SC7E4.11 [Streptomyces coelicolor A3(2)]). pfam02586, DUF159, Uncharacterised ACR, COG2135.; hypothetical protein complement(1731539..1732270) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175245 YP_001222271.1 CDS proV NC_009480.1 1732461 1733366 D putative proline/glycine/betaine/choline ABC transporter, ATP-binding protein (AAP55490.1| PROV-like protein [Leifsonia xyli subsp. xyli]; NP_938494.1| choline transport system ATP-binding protein [Corynebacterium diphtheriae NCTC 13129]). PROBABLY INVOLVED IN OSMOPROTECTION. pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative proline/glycine/betaine/choline ABC transporter ATP-binding protein 1732461..1733366 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175258 YP_001222272.1 CDS proW NC_009480.1 1733363 1734064 D putative proline/glycine/betaine/choline ABC transporter, permease component (YP_062177.1| ABC-type glycine betaine transport, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055115.1| ABC transporter-associated permease [Propionibacterium acnes KPA171202]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative proline/glycine/betaine/choline ABC transporter permease 1733363..1734064 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174153 YP_001222273.1 CDS proZ NC_009480.1 1734061 1734786 D putative proline/glycine/betaine/choline ABC transporter, permease component (YP_062178.1| ABC-type glycine betaine transport, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055114.1| ABC transporter-associated permease [Propionibacterium acnes KPA171202]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative proline/glycine/betaine/choline ABC transporter permease 1734061..1734786 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174301 YP_001222274.1 CDS proX NC_009480.1 1734800 1735729 D putative proline/glycine/betaine/choline ABC transporter, substrate-binding protein (YP_062179.1| ABC-type glycine betaine transport, substrate-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055113.1| putative substrate-binding protein [Propionibacterium acnes KPA171202]). pfam04069, OpuAC, Substrate binding domain of ABC-type glycine betaine transport system. Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation.; Specificity unclear; putative proline/glycine/betaine/choline ABC transporter substrate-binding protein 1734800..1735729 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174057 YP_001222275.1 CDS CMM_1533 NC_009480.1 1735828 1736322 D hypothetical protein 1735828..1736322 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175426 YP_001222276.1 CDS chsA NC_009480.1 1736319 1737539 D putative chalcone synthase/polyketide synthase III (ZP_00225533.1| COG3424: Predicted naringenin-chalcone synthase [Kineococcus radiotolerans SRS30216]; ZP_00204033.1| COG3424: Predicted naringenin-chalcone synthase [Psychrobacter sp. 273-4]). pfam00195,Chal_sti_synt_N, Chalcone and stilbene synthases, N-terminal domain. The C-terminal domain of Chalcone synthase is reported to be structurally; Specificity unclear; putative chalcone synthase/polyketide synthase III 1736319..1737539 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175099 YP_001222277.1 CDS CMM_1535 NC_009480.1 1737539 1738261 D putative methylase (ZP_00225534.1| COG0500: SAM-dependent methyltransferases [Kineococcus radiotolerans SRS30216]; NP_285650.1| hypothetical protein [Deinococcus radiodurans]).; Specificity unclear; hypothetical protein 1737539..1738261 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173634 YP_001222278.1 CDS CMM_1536 NC_009480.1 1738258 1739448 D putative monooxygenase (AAF12452.1| oxidoreductase,putative [Deinococcus radiodurans]; ZP_00225535.1| COG0654: 2-polyprenyl- 6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]). pfam01494, FAD_binding_3, FAD binding domain. This domain is involved in FAD binding in a number of enzymes. pfam01360, Monooxygenase,Monooxygenase. This family includes diverse enzymes that utilise FAD. InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase).; Function unclear; putative monooxygenase 1738258..1739448 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174056 YP_001222279.1 CDS CMM_1537 NC_009480.1 1739441 1740286 R putative polyprenyltransferase (YP_061829.1| 1,4-dihydroxy- 2-naphthoate octaprenyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; CAC17489.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00004483.1| COG0382: 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Rhodobacter sphaeroides]). pfam01040, UbiA, UbiA prenyltransferase family. InterPro: UbiA prenyltransferase.; Function unclear; putative polyprenyltransferase complement(1739441..1740286) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175859 YP_001222280.1 CDS CMM_1538 NC_009480.1 1740283 1740753 R putative acetyltransferase (ZP_00198496.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Kineococcus radiotolerans SRS30216]; ZP_00294382.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Thermobifida fusca]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(1740283..1740753) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174031 YP_001222281.1 CDS CMM_1539 NC_009480.1 1740805 1741338 D putative N-acetyltransferase (ZP_00170037.2| COG1247: Sortase and related acyltransferases [Ralstonia eutropha JMP134]; AAN70415.1| phosphinothricin N-acetyltransferase, putative [Pseudomonas putida KT2440]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase; Function unclear; putative N-acetyltransferase 1740805..1741338 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173776 YP_001222282.1 CDS CMM_1540 NC_009480.1 1741632 1742075 R hypothetical protein complement(1741632..1742075) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175508 YP_001222283.1 CDS cydA NC_009480.1 1742453 1743865 D cytochrome bd-type menaquinol oxidase subunit I (YP_062182.1| cytochrome D ubiquinol oxidase subunit I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628129.1| putative cytochrome oxidase subunit I [Streptomyces coelicolor A3(2)]). pfam01654, Bac_Ubq_Cox, Bacterial Cytochrome Ubiquinol Oxidase. This family are the alternative oxidases found in many bacteria which oxidise ubiquinol and reduce oxygen as part of the electron transport chain.; High confidence in function and specificity; cytochrome bd-type menaquinol oxidase subunit I 1742453..1743865 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173241 YP_001222284.1 CDS cydB NC_009480.1 1743865 1744869 D cytochrome bd-type menaquinol oxidase subunit II (YP_062183.1| cytochrome D ubiquinol oxidase subunit II [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628130.1| putative cytochrome oxidase subunit II [Streptomyces coelicolor A3(2)]). pfam02322, Cyto_ox_2, Cytochrome oxidase subunit II. This Family consists of cytochrome bd type terminal oxidases that catalyses Quinol dependent,Na+ independent oxygen uptake. InterPro: Cytochrome bd ubiquinol oxidase subunit II cydB: cytochrome d ubiquinol oxidase; High confidence in function and specificity; cytochrome bd-type menaquinol oxidase subunit II 1743865..1744869 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174497 YP_001222285.1 CDS cydD NC_009480.1 1744877 1746637 D ABC transporter, ATP-binding protein involved in cytochrome bd biosynthesis (AAP55500.1| cytochrome oxidase subunit IV [Leifsonia xyli subsp. xyli]; NP_628131.1| putative ABC transporter [Streptomyces coelicolor A3(2)]). , pfam00005, ABC_tran, ABC transporter. InterPro: ABC transporter transmembrane region; High confidence in function and specificity; cytochrome bd biosynthesis ABC transporter ATP-binding protein 1744877..1746637 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175811 YP_001222286.1 CDS cydC NC_009480.1 1746634 1748301 D ABC transporter, fused permease/ATP-binding protein involved in the biosynthesis of cytochrom bd (YP_062185.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293394.1| COG4987: ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Thermobifida fusca]). pfam00005, ABC_tran, ABC transporter.; High confidence in function and specificity; transport ATP-binding protein CydC 1746634..1748301 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175863 YP_001222287.1 CDS CMM_1545 NC_009480.1 1748332 1749150 R conserved hypothetical protein, putative 4-amino-4-deoxychorismate lyase (YP_062186.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_822350.1| hypothetical protein SAV1175 [Streptomyces avermitilis MA-4680]).; Function unclear; hypothetical protein complement(1748332..1749150) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174572 YP_001222288.1 CDS trpE2 NC_009480.1 1749204 1750667 D putative anthranilate synthase component I (YP_062187.1| anthranilate synthase component I [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44483.1| anthranilate synthase component I [Tropheryma whipplei str. Twist]). ,pfam04715, Anth_synt_I_N, Anthranilate synthase component I, N terminal region. , pfam00425, Chorismate_bind,chorismate binding enzyme.; High confidence in function and specificity; putative anthranilate synthase component I 1749204..1750667 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173349 YP_001222289.1 CDS leuS NC_009480.1 1750767 1753322 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1750767..1753322 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174696 YP_001222290.1 CDS CMM_1548 NC_009480.1 1753719 1754390 D putative protein involved in DNA uptake (NP_622578.1| DNA uptake protein and related DNA-binding proteins [Thermoanaerobacter tengcongensis]; NP_789319.1| putative DNA uptake protein [Tropheryma whipplei TW08/27]).; Specificity unclear; putative DNA uptake protein 1753719..1754390 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175887 YP_001222291.1 CDS CMM_1549 NC_009480.1 1754387 1756144 D conserved membrane protein, putatively involved in DNA uptake (ZP_00293576.1| COG0658: Predicted membrane metal-binding protein [Thermobifida fusca]). pfam03772,Competence, Competence protein. Members of this family are integral membrane proteins with 6 predicted transmembrane helices. Some members of this family have been shown to be essential for bacterial competence in uptake of extracellular DNA. These proteins may transport DNA across the cell membrane.; Function unclear; DNA uptake membrane protein 1754387..1756144 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175617 YP_001222292.1 CDS holA NC_009480.1 1756230 1757258 D DNA polymerase III, delta subunit (YP_062389.1| DNA polymerase III, delta subunit [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626802.1| putative DNA-binding protein [Streptomyces coelicolor A3(2)]).; High confidence in function and specificity; DNA polymerase III subunit delta 1756230..1757258 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173997 YP_001222293.1 CDS rpsT NC_009480.1 1757361 1757624 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(1757361..1757624) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175606 YP_001222294.1 CDS CMM_1552 NC_009480.1 1757760 1758278 R putative NUDIX hydrolase (NP_822596.1| putative MutT/NUDIX-family protein [Streptomyces avermitilis MA-4680]; ZP_00058247.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Thermobifida fusca]). pfam00293, NUDIX, NUDIX domain.; Function unclear; putative NUDIX hydrolase complement(1757760..1758278) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173937 YP_001222295.1 CDS CMM_1553 NC_009480.1 1758372 1759631 D conserved hypothetical protein, putative amidohydrolase (ZP_00228134.1| COG1228: Imidazolonepropionase and related amidohydrolases [Kineococcus radiotolerans SRS30216]; NP_229522.1| conserved hypothetical protein [Thermotoga maritima]). pfam01979, Amidohydro_1, Amidohydrolase family. This family of enzymes are a a large metal dependent hydrolase superfamily. pyrC_multi: dihydroorotase multifunct; Function unclear; putative amidohydrolase 1758372..1759631 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174245 YP_001222296.1 CDS CMM_1554 NC_009480.1 1759628 1760605 D NDP sugar epimerase, putative cell-division inhibitor (ZP_00225407.2| COG1090: Predicted nucleoside-diphosphate sugar epimerase [Kineococcus radiotolerans SRS30216]; NP_244757.1| cell-division inhibitor [Bacillus halodurans C-125]). pfam01370, Epimerase, NAD dependent epimerase/dehydratase family.; Function unclear; NDP sugar epimerase cell-division inhibitor 1759628..1760605 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173710 YP_001222297.1 CDS lepA NC_009480.1 1760718 1762565 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1760718..1762565 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175521 YP_001222298.1 CDS CMM_1556 NC_009480.1 1762575 1763351 R Hypothetical protein; hypothetical protein complement(1762575..1763351) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173358 YP_001222299.1 CDS CMM_1557 NC_009480.1 1763578 1764357 R Hypothetical protein; hypothetical protein complement(1763578..1764357) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173368 YP_001222300.1 CDS CMM_1558 NC_009480.1 1764671 1765447 R Hypothetical protein; hypothetical protein complement(1764671..1765447) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175548 YP_001222301.1 CDS CMM_1559 NC_009480.1 1765744 1766397 D Region start changed from 1765816 to 1765744 (72 bases); hypothetical protein 1765744..1766397 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174103 YP_001222302.1 CDS CMM_1560 NC_009480.1 1766420 1767121 R putative phosphatase (ZP_00306861.1| COG0546: Predicted phosphatases [Ferroplasma acidarmanus]; ZP_00292966.1| COG0546: Predicted phosphatases [Thermobifida fusca])., , pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This family are structurally different from the alpha/ beta hydrolase family (pfam00561). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.,InterPro: Haloacid dehalogenase/epoxide hydrolase family ,serB: phosphoserine phosphatase SerB; Function unclear; putative phosphatase complement(1766420..1767121) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174609 YP_001222303.1 CDS hemN NC_009480.1 1767201 1768424 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1767201..1768424 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175457 YP_001222304.1 CDS CMM_1562 NC_009480.1 1768440 1768853 R conserved hypothetical protein (NP_824345.1| hypothetical protein SAV3169 [Streptomyces avermitilis MA-4680]; ZP_00292803.1| hypothetical protein Tfus02001595 [Thermobifida fusca]). pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; hypothetical protein complement(1768440..1768853) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174438 YP_001222305.1 CDS CMM_1563 NC_009480.1 1768864 1769259 R conserved hypothetical protein (NP_254020.1| conserved hypothetical protein [Pseudomonas aeruginosa PA01]; AAM41875.1| conserved hypothetical protein [Xanthomonas campestris pv. campestris str. ATCC 33913]).; hypothetical protein complement(1768864..1769259) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175581 YP_001222306.1 CDS hrcA NC_009480.1 1769447 1770469 D Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 1769447..1770469 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174970 YP_001222307.1 CDS dnaJ2 NC_009480.1 1770530 1771645 D chaperone (YP_062381.1| DnaJ protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198394.1| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger domain [Kineococcus radiotolerans SRS30216]). pfam00226,DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. pfam00684, DnaJ_CXXCXGXG,DnaJ central domain (4 repeats). pfam01556, DnaJ_C, DnaJ C terminal region. This family consists of the C terminal region form the DnaJ protein. DnaJ is a chaperone associated with the Hsp70 heat-shock system involved in protein folding and renaturation after stress. InterPro: DnaJ C terminal domain TIGR00270: conserved hypothetical prote; High confidence in function and specificity; chaperone 1770530..1771645 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175465 YP_001222308.1 CDS CMM_1566 NC_009480.1 1771648 1772406 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1771648..1772406 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175008 YP_001222309.1 CDS CMM_1567 NC_009480.1 1772435 1772791 D putative HIT family hydrolase (YP_062379.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00120249.2| COG0537: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Bifidobacterium longum DJO10A]). pfam01230,HIT, HIT domain.; Function unclear; HIT family hydrolase 1772435..1772791 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173826 YP_001222310.1 CDS CMM_1568 NC_009480.1 1772778 1773827 D putative phosphate starvation-induced ATPase (YP_062378.1| phosphate starvation-induced protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826760.1| putative phosphate starvation-induced protein [Streptomyces avermitilis MA-4680]). pfam02562, PhoH, PhoH-like protein. PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation.; Function unclear; putative phosphate starvation-induced ATPase 1772778..1773827 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174661 YP_001222311.1 CDS CMM_1569 NC_009480.1 1773824 1774285 D putative metal-dependent hydrolase (YP_062377.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226332.1| COG0319: Predicted metal-dependent hydrolase [Kineococcus radiotolerans SRS30216]). pfam02130, UPF0054, Uncharacterized protein family UPF0054.; Function unclear; putative metalloprotease 1773824..1774285 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174938 YP_001222312.1 CDS CMM_1570 NC_009480.1 1774294 1775616 D conserved membrane protein (YP_062376.1| hemolysin containing CBS domains [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055649.1| conserved protein, putative hemolysin [Propionibacterium acnes KPA171202]). pfam01595,DUF21, Domain of unknown function DUF21. This transmembrane region has no known function. pfam00571,CBS, CBS domain. CBS domains are small intracellular modules of unknown function. They are mostly found in 2 or four copies within a protein. pfam03471, CorC_HlyC,Transporter associated domain. This small domain is found in a family of proteins with the pfam01595 domain and two CBS domains with this domain found at the C-terminus of the proteins, the domain is also found at the C terminus of some Na+/H+ antiporters. This domain is also found in CorC that is involved in Magnesium and cobalt efflux. The function of this domain is uncertain but might be involved in modulating transport of ion substrates.; Function unclear; hypothetical protein 1774294..1775616 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173789 YP_001222313.1 CDS era NC_009480.1 1775609 1776661 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1775609..1776661 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173942 YP_001222314.1 CDS CMM_1572 NC_009480.1 1776773 1778284 D putative two-component system, sensor kinase (YP_062374.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825857.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system, sensor kinase 1776773..1778284 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173405 YP_001222315.1 CDS CMM_1573 NC_009480.1 1778338 1779024 D putative two-component system, response regulator (YP_062373.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825858.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]). cd00156, REC, Signal receiver domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system, response regulator 1778338..1779024 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174422 YP_001222316.1 CDS CMM_1574 NC_009480.1 1779110 1780513 D putative membrane bound esterase (YP_062370.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00121628.2| COG0627: Predicted esterase [Bifidobacterium longum DJO10A]; NP_939557.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam00756, Esterase, Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function.; Function unclear; putative membrane bound esterase 1779110..1780513 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173544 YP_001222317.1 CDS CMM_1575 NC_009480.1 1780510 1783086 D conserved membrane protein (ZP_00121629.1| COG2898: Uncharacterized conserved protein [Bifidobacterium longum DJO10A]; NP_600193.1| hypothetical protein NCgl0927 [Corynebacterium glutamicum ATCC 13032]). pfam04329,DUF470, Family of unknown function (DUF470). pfam04330,DUF471, Family of unknown function (DUF471). pfam04331,DUF472, Family of unknown function (DUF472). gntP: gluconate transporter; Function unclear; hypothetical protein 1780510..1783086 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173575 YP_001222318.1 CDS leuA NC_009480.1 1783252 1785018 D 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (YP_062368.1| 2-isopropylmalate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226323.1| COG0119: Isopropylmalate/homocitrate/ citramalate synthases [Kineococcus radiotolerans SRS30216]).; High confidence in function and specificity; 2-isopropylmalate synthase 1783252..1785018 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175499 YP_001222319.1 CDS CMM_1577 NC_009480.1 1785110 1785787 R conserved membrane protein (YP_062367.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_718896.1| conserved hypothetical protein [Shewanella oneidensis MR-1]). pfam03458, UPF0126, UPF0126 domain. Domain always found as pair in bacterial membrane proteins of unknown function. This domain contains three transmembrane helices. The conserved glycines are suggestive of an ion channel (C. Yeats unpublished obs.)(duplicated).; hypothetical protein complement(1785110..1785787) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175914 YP_001222320.1 CDS recO NC_009480.1 1785906 1786835 D DNA repair protein/recombination protein (Q9L2H3|RECO_STRCO DNA repair protein recO (Recombination protein O); ZP_00226321.1| COG1381: Recombinational DNA repair protein (RecF pathway)[Kineococcus radiotolerans SRS30216]). pfam02565, RecO, Recombination protein O.; High confidence in function and specificity; DNA repair protein /recombination protein 1785906..1786835 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174886 YP_001222321.1 CDS uppS1 NC_009480.1 1786832 1787698 D putative undecaprenyl pyrophosphate synthetase (YP_062365.1| undecaprenyl pyrophosphate synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; Q82BS5|UPS2_STRAW Undecaprenyl pyrophosphate synthetase 2 (UPP synthetase 2)(Di-trans-poly-cis-decaprenylcistransferase 2)). , pfam01255,UPP_synthetase, Putative undecaprenyl diphosphate synthase. , InterPro: Undecaprenyl pyrophosphate synthetase family; High confidence in function and specificity; putative undecaprenyl pyrophosphate synthetase 1786832..1787698 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172948 YP_001222322.1 CDS CMM_1580 NC_009480.1 1787708 1788817 D putative oxidoreductase (NP_627076.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]; AAT60489.1| oxidoreductase, Gfo/Idh/MocA family [Bacillus thuringiensis serovar konkukian str. 97-27]). pfam01408,GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. pfam02894, GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain.; Function unclear; putative oxidoreductase 1787708..1788817 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173490 YP_001222323.1 CDS glyS NC_009480.1 1788928 1790313 D Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 1788928..1790313 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173365 YP_001222324.1 CDS CMM_1582 NC_009480.1 1790365 1790829 R conserved hypothetical protein (YP_056922.1| putative transcriptional regulator [Propionibacterium acnes KPA171202]; NP_484703.1| probable transcription regulator [Nostoc sp. PCC 7120]). pfam04073, YbaK, YbaK / prolyl-tRNA synthetases associated domain. This domain of unknown function is found in numerous prokaryote organisms.; hypothetical protein complement(1790365..1790829) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173792 YP_001222325.1 CDS CMM_1583 NC_009480.1 1790950 1791675 D conserved hypothetical protein (ZP_00226827.1| COG2761: Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Kineococcus radiotolerans SRS30216]; NP_294382.1| frnE protein [Deinococcus radiodurans]; CAF21228.1| Predicted dithiol-disulfide isomerase [Corynebacterium glutamicum ATCC 13032]). pfam01323, DSBA, DSBA-like thioredoxin domain. This family contains a diverse set of proteins with a thioredoxin-like structure pfam00085. This family also includes 2-hydroxychromene-2-carboxylate (HCCA) isomerase enzymes catalyse one step in prokaryotic polyaromatic hydrocarbon (PAH) catabolic pathways.; Function unclear; hypothetical protein 1790950..1791675 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174613 YP_001222326.1 CDS dusA NC_009480.1 1791958 1793190 D putative tRNA-dihydrouridine synthase (ZP_00225742.1| COG0042: tRNA-dihydrouridine synthase [Kineococcus radiotolerans SRS30216]; NP_626738.1| conserved hypothetical protein SCC82.03c [Streptomyces coelicolor A3(2)]). Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity). pfam01207, Dus, Dihydrouridine synthase (Dus). Members of this family catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA.; Specificity unclear; putative tRNA-dihydrouridine synthase 1791958..1793190 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175005 YP_001222327.1 CDS dgtA NC_009480.1 1793195 1794454 D dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 1793195..1794454 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175694 YP_001222328.1 CDS dnaG NC_009480.1 1794549 1796438 D synthesizes RNA primers at the replication forks; DNA primase 1794549..1796438 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175675 YP_001222329.1 CDS CMM_1587 NC_009480.1 1796639 1798294 D putative oligopeptide ABC transporter, substrate-binding protein (YP_061855.1| ABC transporter, solute-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696509.1| probable solute-binding protein of ABC transporter for peptides [Bifidobacterium longum NCC2705]; NP_827846.1| putative solute binding transport lipoprotein [Streptomyces avermitilis MA-4680]). pfam00496, SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative oligopeptide ABC transporter substrate-binding protein 1796639..1798294 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175897 YP_001222330.1 CDS CMM_1588 NC_009480.1 1798439 1799533 D putative oligopeptide ABC transporter, permease component (YP_061856.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696510.1| probable permease of ABC transporter for peptides [Bifidobacterium longum NCC2705]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative oligopeptide ABC transporter permease 1798439..1799533 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173991 YP_001222331.1 CDS CMM_1589 NC_009480.1 1799535 1800557 D putative oligopeptide ABC transporter, permease component(ZP_00120658.1| COG1173: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Bifidobacterium longum DJO10A]; YP_061857.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative oligopeptide ABC transporter permease 1799535..1800557 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174937 YP_001222332.1 CDS CMM_1590 NC_009480.1 1800554 1802266 D putative oligopeptide ABC transporter, ATP-binding protein (duplicated ATPase domain; YP_061858.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696512.1| ATP binding protein of ABC transporter [Bifidobacterium longum NCC2705]).; Specificity unclear; putative oligopeptide ABC transporter ATP-binding protein 1800554..1802266 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174707 YP_001222333.1 CDS CMM_1591 NC_009480.1 1802380 1803327 D putative oligopeptide ABC transporter, ATP-binding protein (YP_061859.1| oligopeptide porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_798466.1| oligopeptide ABC transporter, ATP-binding protein [Vibrio parahaemolyticus RIMD 2210633]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative oligopeptide ABC transporter ATP-binding protein 1802380..1803327 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175616 YP_001222334.1 CDS CMM_1592 NC_009480.1 1803438 1804343 D putative 2-hydroxyacid dehydrogenase (YP_061860.1| phosphoglycerate dehydrogenase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226123.1| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [Kineococcus radiotolerans SRS30216]). pfam02826, 2-Hacid_dh_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain.; Specificity unclear; putative 2-hydroxyacid dehydrogenase 1803438..1804343 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174276 YP_001222335.1 CDS CMM_1593 NC_009480.1 1804431 1805438 D conserved hypothetical protein (ZP_00058653.1| COG2706: 3-carboxymuconate cyclase [Thermobifida fusca]; NP_822705.1| putative secreted protein [Streptomyces avermitilis MA-4680]).; Function unclear; hypothetical protein 1804431..1805438 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175613 YP_001222336.1 CDS CMM_1594 NC_009480.1 1805458 1805826 R hypothetical protein complement(1805458..1805826) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175513 YP_001222337.1 CDS defA NC_009480.1 1806057 1806623 R putative polypeptide deformylase (YP_061861.1| polypeptide deformylase [Leifsonia xyli subsp. xyli str. CTCB07]; Q83HQ3|DEF_TROW8 Peptide deformylase (PDF) (Polypeptide deformylase); P96275|DEF_MYCTU Peptide deformylase (PDF) (Polypeptide deformylase)). pfam01327,Pep_deformylase, Polypeptide deformylase.; High confidence in function and specificity; putative polypeptide deformylase complement(1806057..1806623) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173677 YP_001222338.1 CDS wcmE NC_009480.1 1806663 1807574 D conserved membrane protein, putative transporter of the DMT family (YP_061862.1| Integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789391.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; ZP_00059265.1| COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily [Thermobifida fusca]).; Family membership; exporter DMT family membrane protein 1806663..1807574 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173787 YP_001222339.1 CDS wcmF NC_009480.1 1807755 1809014 D putative glycosyltransferase (YP_061863.1| glucosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787440.1| glycosyltransferase [Tropheryma whipplei str. Twist]; ZP_00058706.1| COG0438: Glycosyltransferase [Thermobifida fusca]). pfam00534,Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP,ADP, GDP or CMP linked sugars. InterPro: Glycosyl transferases group 1; Specificity unclear; putative glycosyltransferase 1807755..1809014 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174868 YP_001222340.1 CDS wcmG NC_009480.1 1809356 1811548 D putative membrane-.bound acyltranferase (ZP_00057849.1| COG1835: Predicted acyltransferases [Thermobifida fusca]; NP_962944.1| hypothetical protein MAP4010c [Mycobacterium avium subsp. paratuberculosis str. k10]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes.; Specificity unclear; putative membrane-bound acyltranferase 1809356..1811548 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175638 YP_001222341.1 CDS fclA NC_009480.1 1811648 1812652 R putative fucose synthase (GDP-4-keto-6-deoxy-D-mannose- 3,5-epimerase-4-reductase) (NP_336015.1| fucose synthetase [Mycobacterium tuberculosis CDC1551]; ZP_00199161.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]). pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor.; High confidence in function and specificity; hypothetical protein complement(1811648..1812652) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173332 YP_001222342.1 CDS gmdA NC_009480.1 1812649 1813701 R putative D-GDP-mannose dehydratase (EC 4.2.1.47) (AAN05764.1| GDP-D-mannose-dehydratase MdhtA [Mycobacterium avium]; ZP_00227152.1| COG1089: GDP-D-mannose dehydratase [Kineococcus radiotolerans SRS30216]). Conversion of GDP-D-mannose to GDP-4-keto-6-D-deoxymannose (By similarity). PUTATIVELY INVOLVED IN EPS BIOSYNTHESIS pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; High confidence in function and specificity; putative GDP-mannose 4,6-dehydratase complement(1812649..1813701) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175117 YP_001222343.1 CDS wcmH NC_009480.1 1813877 1815163 D putative glycosyl transferase (ZP_00225721.1| COG0438: Glycosyltransferase [Kineococcus radiotolerans SRS30216]; ZP_00049876.2| COG0438: Glycosyltransferase [Magnetospirillum magnetotacticum]; NP_707945.1| putative colanic biosynthesis glycosyl transferase [Shigella flexneri 2a str. 301]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Specificity unclear; putative glycosyltransferase 1813877..1815163 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173531 YP_001222344.1 CDS wcmI NC_009480.1 1815160 1815744 D putative acetyltransferase involved in polysaccharide biosynthesis (ZP_00033229.1| COG0110: Acetyltransferase (isoleucine patch superfamily)[Burkholderia fungorum]; NP_864963.1| putative colanic acid biosynthesis acetyltransferase [Pirellula sp. 1]; ZP_00227153.1| COG0110: Acetyltransferase (isoleucine patch superfamily)[Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative acetyltransferase involved in polysaccharide biosynthesis 1815160..1815744 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172946 YP_001222345.1 CDS wcmJ NC_009480.1 1815849 1816784 D putative pyruvyltransferase (YP_009110.1| conserved domain protein [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough]; only weak similarities to: CAB01946.1| ExpA4 [Sinorhizobium meliloti]; AMSJ_ERWAM Amylovoran biosynthesis protein amsJ). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam04230, PS_pyruv_trans,Polysaccharide pyruvyl transferase. Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis.; Hypothetical protein; putative pyruvyltransferase 1815849..1816784 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172978 YP_001222346.1 CDS wcmK NC_009480.1 1816781 1818013 D putative glycosyl transferase (sp|P71237|WCAC_ECOLI Putative colanic acid biosynthesis glycosyl transferase wcaC; NP_707952.1| putative glycosyl transferase [Shigella flexneri 2a str. 301]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Specificity unclear; putative glycosyl transferase 1816781..1818013 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172988 YP_001222347.1 CDS wcaD NC_009480.1 1818010 1819293 D wzy1; essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; putative colanic acid biosynthesis protein 1818010..1819293 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172990 YP_001222348.1 CDS CMM_1606 NC_009480.1 1819193 1819942 D Region start changed from 1819358 to 1819193 (165 bases); putative glycosyl transferase 1819193..1819942 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174012 YP_001222349.1 CDS wcmM NC_009480.1 1819939 1820442 D putative serine acetyltransferase (NP_745280.1| serine O-acetyltransferase, putative [Pseudomonas putida KT2440]; NP_228475.1| serine acetyltransferase [Thermotoga maritima]) . PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. InterPro: Bacterial transferase hexapeptide repeat; Specificity unclear; putative serine acetyltransferase 1819939..1820442 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175886 YP_001222350.1 CDS wzx1 NC_009480.1 1820477 1821901 D putative membrane protein involved in the synthesis/export of EPS (NP_105963.1| probable succinoglycan transport protein [Mesorhizobium loti]; NP_266368.1| polysaccharide biosynthesis export protein [Lactococcus lactis subsp. lactis]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam01943, Polysacc_synt,Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins.; Family membership; putative membrane protein involved in the export of EPS 1820477..1821901 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173007 YP_001222351.1 CDS wcmN NC_009480.1 1821917 1823482 R putative undecaprenyl-phosphate glycosyl-1-phosphate transferase (NP_959898.1| hypothetical protein MAP0964c [Mycobacterium avium subsp. paratuberculosis str. k10]; AAM94041.1| putative undecaprenyl-phosphate glycosyl-1-phosphate transferase; glucose-1-phosphate transferase [Streptomyces sp. 139]; NP_695455.1| undecaprenyl-phosphate sugar phosphotransferase [Bifidobacterium longum NCC2705]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.; Specificity unclear; putative undecaprenyl-phosphate glycosyl-1-phosphate transfe complement(1821917..1823482) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173981 YP_001222352.1 CDS CMM_1610 NC_009480.1 1823628 1823915 R hypothetical protein (ZP_00049742.1| hypothetical protein Magn023325 [Magnetospirillum magnetotacticum]).; hypothetical protein complement(1823628..1823915) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173051 YP_001222353.1 CDS cspA1 NC_009480.1 1824033 1824236 R putative cold shock protein A (ZP_00047730.1| COG1278: Cold shock proteins [Magnetospirillum magnetotacticum]; YP_063017.1| cold shock protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00313, CSD,'Cold-shock' DNA-binding domain. InterPro: Cold-shock DNA-binding domain; Family membership; putative cold shock protein complement(1824033..1824236) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173743 YP_001222354.1 CDS polA2 NC_009480.1 1824495 1826165 D putative DNA polymerase I (YP_061866.1| DNA polymerase I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_733604.1| putative DNA polymerase I [Streptomyces coelicolor A3(2)]). pfam00476, DNA_pol_A, DNA polymerase family A. InterPro: Replicative DNA polymerase; Specificity unclear; putative DNA polymerase I 1824495..1826165 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174602 YP_001222355.1 CDS CMM_1612A NC_009480.1 1826256 1826405 D hypothetical protein 1826256..1826405 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173186 YP_001222356.1 CDS CMM_1613 NC_009480.1 1826513 1827364 D conserved hypothetical protein (YP_061867.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626020.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1826513..1827364 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173393 YP_001222357.1 CDS CMM_1614 NC_009480.1 1827366 1827968 R putative transcriptional regulator, PadR family (YP_054926.1| transcriptional regulator [Propionibacterium acnes KPA171202]; NP_737543.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam03551,PadR, Transcriptional regulator PadR-like family.; Specificity unclear; PadR family transcriptional regulator complement(1827366..1827968) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174169 YP_001222358.1 CDS CMM_1615 NC_009480.1 1828232 1828750 D conserved hypothetical protein (YP_061869.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00190504.2| hypothetical protein Krad06002672 [Kineococcus radiotolerans SRS30216]; NP_826961.1| hypothetical protein SAV5784 [Streptomyces avermitilis MA-4680]).; hypothetical protein 1828232..1828750 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175488 YP_001222359.1 CDS fabF NC_009480.1 1828844 1830085 R 3-oxoacyl-[acyl-carrier-protein] synthase 1 (Beta-ketoacyl-ACP synthase 1) (YP_062220.1| 3-oxoacyl-[acyl-carrier-protein] synthase I [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226800.1| COG0304: 3-oxoacyl-(acyl-carrier-protein) synthase [Kineococcus radiotolerans SRS30216]). Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity). pfam00109,ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain. pfam02801, Ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain. InterPro: Beta-ketoacyl synthase.; High confidence in function and specificity; 3-oxoacyl-ACP synthase complement(1828844..1830085) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174099 YP_001222360.1 CDS acpP NC_009480.1 1830165 1830413 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(1830165..1830413) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173830 YP_001222361.1 CDS fabH NC_009480.1 1830467 1831480 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase complement(1830467..1831480) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175682 YP_001222362.1 CDS fabD NC_009480.1 1831511 1832431 R putative malonyl CoA-acyl carrier protein transacylase (YP_062217.1| [acyl-carrier protein] S-malonyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626633.1| malonyl CoA:acyl carrier protein malonyltransferase [Streptomyces coelicolor A3(2)]). pfam00698, Acyl_transf_1, Acyl transferase domain. InterPro: Acyl transferase domain fabD: malonyl CoA-acyl carrier protein; High confidence in function and specificity; putative malonyl CoA-acyl carrier protein transacylase complement(1831511..1832431) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175415 YP_001222363.1 CDS CMM_1620 NC_009480.1 1832526 1833800 R putative transcriptional regulator (YP_062216.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826966.1| hypothetical protein SAV5789 [Streptomyces avermitilis MA-4680]).; Function unclear; putative transcriptional regulator complement(1832526..1833800) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174342 YP_001222364.1 CDS aceE NC_009480.1 1833817 1836543 R E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 complement(1833817..1836543) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173148 YP_001222365.1 CDS ahpE NC_009480.1 1836784 1837257 D putative thiol-specific antioxidant protein,thioredoxin peroxidase (YP_062214.1| AhpC/TSA family protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626616.1| putative thiol-specific antioxidant protein [Streptomyces coelicolor A3(2)]). pfam00578, AhpC-TSA,AhpC/TSA family. This family contains proteins related to alkyl hydroperoxide reductase (AhpC) and thiol specific antioxidant (TSA).; Family membership; putative thiol-specific antioxidant protein 1836784..1837257 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173231 YP_001222366.1 CDS CMM_1623 NC_009480.1 1837286 1837975 R putative membrane protein (NP_103276.1| unknown protein [Mesorhizobium loti MAFF303099]; NP_868937.1| conserved hypothetical protein [Pirellula sp. 1]). pfam07077, DUF1345, Protein of unknown function (DUF1345).; hypothetical protein complement(1837286..1837975) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173039 YP_001222367.1 CDS CMM_1624 NC_009480.1 1838182 1838772 R putative transcriptional regulator, TetR family (YP_062890.1| transcriptional regulator, TetR family [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056115.1| tetracycline repressor protein [Propionibacterium acnes KPA171202]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.; Specificity unclear; TetR family transcriptional regulator complement(1838182..1838772) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174721 YP_001222368.1 CDS CMM_1625 NC_009480.1 1838853 1839494 D conserved membrane protein, BioY-family (YP_062891.1| biotin synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_979945.1| bioY family protein [Bacillus cereus ATCC 10987]; NP_787339.1| biotin synthesis BioY protein [Tropheryma whipplei str. Twist]) pfam02632, BioY,BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin.; Conserved hypothetical protein; membrane protein BioY family 1838853..1839494 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173473 YP_001222369.1 CDS CMM_1626 NC_009480.1 1839509 1840195 D putative metal ABC transporter, ATP-binding protein (YP_062894.1| ABC- transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00269416.1| COG1122: ABC-type cobalt transport system, ATPase component [Rhodospirillum rubrum]). pfam00005, ABC_tran,ABC transporter. InterPro: AAA ATPase superfamily; Specificity unclear; putative metal ABC transporter ATP-binding protein 1839509..1840195 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174085 YP_001222370.1 CDS CMM_1627 NC_009480.1 1840192 1840803 D putative metal ABC transporter, permease component (YP_062895.1| ABC-type cobalt transport system, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00271172.1| COG0619: ABC-type cobalt transport system,permease component CbiQ and related transporters [Rhodospirillum rubrum]). pfam02361, CbiQ, Cobalt transport protein.; Specificity unclear; putative metal ABC transporter permease 1840192..1840803 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173688 YP_001222371.1 CDS CMM_1628 NC_009480.1 1840889 1841080 D hypothetical protein 1840889..1841080 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172919 YP_001222372.1 CDS CMM_1629 NC_009480.1 1841133 1841960 D conserved hypothetical protein (YP_061971.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789442.1| conserved hypothetical protein [Tropheryma whipplei TW08/27]; ZP_00059437.1| COG0327: Uncharacterized conserved protein [Thermobifida fusca]). pfam01784, NIF3, NIF3 (NGG1p interacting factor 3). TIGR00486: conserved hypothetical prote; Function unclear; hypothetical protein 1841133..1841960 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174112 YP_001222373.1 CDS CMM_1630 NC_009480.1 1842052 1842786 D conserved hypothetical protein (YP_061972.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226791.1| COG1579: Zn-ribbon protein,nucleic acid-binding [Kineococcus radiotolerans SRS30216]). pfam02591, DUF164, Uncharacterized ACR,COG1579. InterPro: DUF164; Function unclear; hypothetical protein 1842052..1842786 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172930 YP_001222374.1 CDS ppgK1 NC_009480.1 1843281 1844102 R putative polyphosphate glucokinase (Polyphosphate-glucose phosphotransferase) (YP_061973.1| glucokinase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056789.1| polyphosphate glucokinase/ transcriptional regulator [Propionibacterium acnes KPA171202]). , pfam00480, ROK,ROK family. , glk: glucokinase; Specificity unclear; putative polyphosphate glucokinase complement(1843281..1844102) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174801 YP_001222375.1 CDS CMM_1632 NC_009480.1 1844177 1844359 D conserved hypothetical protein (NP_940013.1| Conserved hypothetical protein [Corynebacterium diphtheriae NCTC 13129]; ZP_00121553.1| hypothetical protein Blon021481 [Bifidobacterium longum DJO10A]).; hypothetical protein 1844177..1844359 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175118 YP_001222376.1 CDS panB NC_009480.1 1844369 1845238 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(1844369..1845238) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172944 YP_001222377.1 CDS glnA2 NC_009480.1 1845324 1846661 D putative glutamine synthetase II (Glutamate--ammonia ligase 2)(YP_061977.1| glutamine synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226485.1| COG0174: Glutamine synthetase [Kineococcus radiotolerans SRS30216]). pfam03951, Gln-synt_N, Glutamine synthetase,beta-Grasp domain. pfam00120, Gln-synt_C, Glutamine synthetase, catalytic domain. InterPro: Glutamine synthetase.; High confidence in function and specificity; putative glutamine synthetase II 1845324..1846661 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175400 YP_001222378.1 CDS glnE NC_009480.1 1846720 1849740 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 1846720..1849740 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175002 YP_001222379.1 CDS glnA1 NC_009480.1 1849834 1851258 R Glutamine synthetase I (Glutamate--ammonia ligase) (YP_061980.1| glutamine synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198695.2| COG0174: Glutamine synthetase [Kineococcus radiotolerans SRS30216]). pfam03951, Gln-synt_N, Glutamine synthetase, beta-Grasp domain. pfam00120, Gln-synt_C, Glutamine synthetase,catalytic domain. GlnA: glutamine synthetase type I; High confidence in function and specificity; glutamine synthetase complement(1849834..1851258) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175158 YP_001222380.1 CDS CMM_1637 NC_009480.1 1851451 1851879 D conserved membrane protein (YP_061981.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626449.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00189987.2| COG1714: Predicted membrane protein/domain [Kineococcus radiotolerans SRS30216]). pfam06271, RDD, RDD family.; Function unclear; hypothetical protein 1851451..1851879 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173611 YP_001222381.1 CDS CMM_1638 NC_009480.1 1851905 1852630 R putative chaperone ( pfam00226, DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction.; Family membership; putative chaperone complement(1851905..1852630) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173475 YP_001222382.1 CDS CMM_1639 NC_009480.1 1852685 1853395 R conserved membrane protein (YP_061982.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198696.2| hypothetical protein Krad06003323 [Kineococcus radiotolerans SRS30216]).; Conserved hypothetical protein; hypothetical protein complement(1852685..1853395) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174008 YP_001222383.1 CDS pknD NC_009480.1 1853609 1855297 D putative serine/threonine protein kinase (AAO44694.1| putative serine/threonine-protein kinase [Tropheryma whipplei str. Twist]; NP_601379.1| serine/threonine protein kinase [Corynebacterium glutamicum ATCC 13032]). pfam00069, Pkinase, Protein kinase domain. smart00220, S_TKc, Serine/Threonine protein kinases, catalytic domain; Phosphotransferases. Serine or threonine-specific kinase subfamily.; Family membership; putative serine/threonine protein kinase 1853609..1855297 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173580 YP_001222384.1 CDS aceF NC_009480.1 1855324 1856766 R putative pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component (YP_061986.1| dihydrolipoamide acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789198.1| putative lipoamide acyltransferase [Tropheryma whipplei TW08/27]). pfam00364, Biotin_lipoyl, Biotin-requiring enzyme. pfam02817, E3_binding, e3 binding domain. This family represents a small domain of the E2 subunit of 2-oxo-acid dehydrogenases responsible for the binding of the E3 subunit. pfam00198, 2-oxoacid_dh, 2-oxoacid dehydrogenases acyltransferase (catalytic domain).; Specificity unclear; putative pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component complement(1855324..1856766) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173470 YP_001222385.1 CDS lpdB NC_009480.1 1856827 1858200 R E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(1856827..1858200) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173423 YP_001222386.1 CDS pepA NC_009480.1 1858292 1859800 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(1858292..1859800) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174383 YP_001222387.1 CDS CMM_1644 NC_009480.1 1859970 1860890 D conserved hypothetical protein (YP_061989.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058376.1| hypothetical protein [Thermobifida fusca]; NP_961765.1| hypothetical protein MAP2831 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam05601, DUF774, Protein of unknown function (DUF774). This family consists of several uncharacterised Actinomycete proteins of unknown function.; Function unclear; hypothetical protein 1859970..1860890 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175189 YP_001222388.1 CDS CMM_1645 NC_009480.1 1860965 1862287 D putative MFS permease (YP_061990.1| major facilitator superfamily permease [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226285.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam00083, Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters.; Specificity unclear; putative MFS permease 1860965..1862287 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174752 YP_001222389.1 CDS sigA NC_009480.1 1862537 1864015 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor 1862537..1864015 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173366 YP_001222390.1 CDS murX NC_009480.1 1864019 1865299 D putative UDP-N-acetylmuramyl tripeptide synthase(YP_061992.1| UDP-N-acetylmuramyl tripeptide synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787626.1| UDP-N-acetylmuramyl tripeptide synthase-like protein [Tropheryma whipplei str. Twist]). , pfam01225,Mur_ligase, Mur ligase family, catalytic domain. ,InterPro: Cytoplasmic peptidoglycan synthetases N-terminal.; High confidence in function and specificity; putative UDP-N-acetylmuramyl tripeptide synthase 1864019..1865299 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175188 YP_001222391.1 CDS CMM_1648 NC_009480.1 1865296 1866030 D putative glutamine amidotransferase (YP_061993.1| cobyric acid synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_621720.1| predicted glutamine amidotransferase [Thermoanaerobacter tengcongensis]; AAC84011.1| cobyric acid synthase CobQ [Heliobacillus mobilis]).; Function unclear; putative glutamine amidotransferase 1865296..1866030 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173228 YP_001222392.1 CDS CMM_1649 NC_009480.1 1866133 1866360 R conserved hypothetical protein (YP_062003.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226189.1| hypothetical protein Krad06003778 [Kineococcus radiotolerans SRS30216]).; hypothetical protein complement(1866133..1866360) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173140 YP_001222393.1 CDS CMM_1650 NC_009480.1 1866573 1868651 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1866573..1868651 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174670 YP_001222394.1 CDS CMM_1651 NC_009480.1 1868733 1871279 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(1868733..1871279) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173479 YP_001222395.1 CDS CMM_1652 NC_009480.1 1871364 1872503 D conserved hypothetical protein (ZP_00226205.1| COG1524: Uncharacterized proteins of the AP superfamily [Kineococcus radiotolerans SRS30216]; ZP_00291972.1| COG1524: Uncharacterized proteins of the AP superfamily [Thermobifida fusca]). pfam01663, Phosphodiest, Type I phosphodiesterase/nucleotide pyrophosphatase.; hypothetical protein 1871364..1872503 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173495 YP_001222396.1 CDS CMM_1653 NC_009480.1 1872559 1873749 R putative DNA-binding protein (NP_789210.1| conserved DNA-binding protein [Tropheryma whipplei TW08/27]; NP_629978.1| putative DNA-binding protein [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(1872559..1873749) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173564 YP_001222397.1 CDS CMM_1654 NC_009480.1 1874075 1874368 D conserved hypothetical protein (YP_062008.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226691.1| hypothetical protein Krad06002945 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1874075..1874368 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173990 YP_001222398.1 CDS CMM_1655 NC_009480.1 1874416 1874865 R putative membrane protein (NP_789212.1| putative membrane protein [Tropheryma whipplei TW08/27]; NP_629988.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; Conserved hypothetical protein; hypothetical protein complement(1874416..1874865) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173134 YP_001222399.1 CDS dutA NC_009480.1 1874904 1875374 D putative deoxyuridine 5'-triphosphate pyrophosphatase (NP_823575.1| putative deoxyuridine 5'-triphosphate pyrophosphatase [Streptomyces avermitilis MA-4680]; NP_789213.1| deoxyuridine 5'-triphosphate nucleotidohydrolase [Tropheryma whipplei TW08/27]). pfam00692, dUTPase, dUTPase. dUTPase hydrolyses dUTP to dUMP and pyrophosphate.; High confidence in function and specificity; hypothetical protein 1874904..1875374 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173488 YP_001222400.1 CDS CMM_1657 NC_009480.1 1875371 1876063 D conserved hypothetical protein (NP_787614.1| unknown [Tropheryma whipplei str. Twist]; NP_823574.1| hypothetical protein SAV2398 [Streptomyces avermitilis MA-4680]).; hypothetical protein 1875371..1876063 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174465 YP_001222401.1 CDS CMM_1658 NC_009480.1 1876066 1876857 D conserved membrane protein (NP_629996.1| putative membrane protein [Streptomyces coelicolor A3(2)]; NP_696556.1| narrowly conserved hypothetical transmembrane protein [Bifidobacterium longum NCC2705]).; Conserved hypothetical protein; hypothetical protein 1876066..1876857 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172949 YP_001222402.1 CDS acnA NC_009480.1 1877093 1879906 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1877093..1879906 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173139 YP_001222403.1 CDS dxsA NC_009480.1 1879985 1881973 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1879985..1881973 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175323 YP_001222404.1 CDS fadB NC_009480.1 1882035 1884164 R Fatty oxidation complex alpha subunit (ZP_00294150.1| COG1250: 3-hydroxyacyl-CoA dehydrogenase [Thermobifida fusca]; NP_823410.1| putative fatty acid oxidation complex alpha-subunit [Streptomyces avermitilis MA-4680]). FAOA AND FAOB ARE THE ALPHA AND BETA SUBUNITS OF THE MULTIFUNCTIONAL ENZYME COMPLEX OF THE FATTY ACID DEGRADATION CYCLE. N-terminal: COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase; pfam00378, ECH, Enoyl-CoA hydratase/isomerase family. C-terminal: COG1250, FadB, 3-hydroxyacyl-CoA dehydrogenase; pfam02737, 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. pfam00725, 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain (twice).; High confidence in function and specificity; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase complement(1882035..1884164) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174595 YP_001222405.1 CDS fadA NC_009480.1 1884161 1885369 R putative 3-oxoacyl-CoA thiolase (NP_823409.1| putative 3-oxoacyl-CoA thiolase [Streptomyces avermitilis MA-4680]; ZP_00294151.1| COG0183: Acetyl-CoA acetyltransferase [Thermobifida fusca]). pfam00108,Thiolase_N, Thiolase, N-terminal domain. pfam02803,Thiolase_C, Thiolase, C-terminal domain.; High confidence in function and specificity; putative 3-oxoacyl-CoA thiolase complement(1884161..1885369) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175369 YP_001222406.1 CDS CMM_1663 NC_009480.1 1885441 1886931 R putative Ribonuclease D (NP_630139.1| putative ribonuclease [Streptomyces coelicolor A3(2)]; ZP_00294153.1| COG0349: Ribonuclease D [Thermobifida fusca]). InterPro: 3-5 exonuclease. pfam01612, 3_5_exonuc,3'-5' exonuclease. pfam00570, HRDC, HRDC domain. The HRDC (Helicase and RNase D C-terminal) domain has a putative role in nucleic acid binding.; Specificity unclear; putative ribonuclease D complement(1885441..1886931) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173854 YP_001222407.1 CDS CMM_1664 NC_009480.1 1886928 1887524 R conserved hypothetical protein (ZP_00226661.1| hypothetical protein Krad06002913 [Kineococcus radiotolerans SRS30216]; NP_630141.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(1886928..1887524) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172920 YP_001222408.1 CDS CMM_1665 NC_009480.1 1887619 1888365 R putative pyrimidine reductase (NP_787520.1| 5-amino-6-(5-phospho- ribosylamino)uracil reductase [Tropheryma whipplei str. Twist]; ZP_00292785.1| COG1985: Pyrimidine reductase, riboflavin biosynthesis [Thermobifida fusca]). pfam01872, RibD_C, RibD C-terminal domain.; Function unclear; putative pyrimidine reductase complement(1887619..1888365) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172965 YP_001222409.1 CDS CMM_1666 NC_009480.1 1888362 1888802 R conserved protein putatively involved in Fe-S assembly (ZP_00228362.1| COG2166: SufE protein probably involved in Fe-S center assembly [Kineococcus radiotolerans SRS30216]; CAB07067.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). InterPro: UPF0050_DUF pfam02657, SufE, Fe-S metabolism associated domain. This family consists of the SufE-related proteins. These have been implicated in Fe-S metabolism and export.; Function unclear; hypothetical protein complement(1888362..1888802) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172984 YP_001222410.1 CDS sseA NC_009480.1 1888799 1889710 R Thiosulfate sulfurtransferase (ZP_00228363.1| COG2897: Rhodanese-related sulfurtransferase [Kineococcus radiotolerans SRS30216]; P96888|THT2_MYCTU Putative thiosulfate sulfurtransferase SSEA). pfam00581, Rhodanese,Rhodanese-like domain. Rhodanese has an internal duplication.; High confidence in function and specificity; thiosulfate sulfurtransferase complement(1888799..1889710) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172995 YP_001222411.1 CDS CMM_1668 NC_009480.1 1889879 1890943 D putative ATPase (NP_823384.1| putative ATP/GTP-binding protein [Streptomyces avermitilis MA-4680]; ZP_00228364.1| COG1485: Predicted ATPase [Kineococcus radiotolerans SRS30216]). pfam03969, AFG1_ATPase, AFG1-like ATPase. This family of proteins contains a P-loop motif and are predicted to be ATPases.; Function unclear; putative ATPase 1889879..1890943 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175927 YP_001222412.1 CDS amtB NC_009480.1 1891196 1892482 D putative ammonium transporter, Amt family (ZP_00225603.1| COG0004: Ammonia permease [Kineococcus radiotolerans SRS30216]; Q10968|AMT_MYCTU Probable ammonium transporter)., , pfam00909, Ammonium_transp,Ammonium Transporter Family.; High confidence in function and specificity; ammonium transporter 1891196..1892482 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173016 YP_001222413.1 CDS CMM_1670 NC_009480.1 1892731 1893570 D putative aldo/keto-reductase (NP_823025.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]; BAB99752.1| Aldo/keto reductases, related to diketogulonate reductase [Corynebacterium glutamicum ATCC 13032]). InterPro: Aldo/keto reductase family pfam00248,Aldo_ket_red, Aldo/keto reductase family.; Function unclear; oxidoreductase 1892731..1893570 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174820 YP_001222414.1 CDS CMM_1671 NC_009480.1 1893777 1894208 D hypothetical protein (only weak match to putative transcriptional regulator (NP_784581.1| transcription regulator [Lactobacillus plantarum WCFS1]).; hypothetical protein 1893777..1894208 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173064 YP_001222415.1 CDS CMM_1672 NC_009480.1 1894205 1895071 D putative methyltransferase, HemK family (NP_822468.1| putative methytransferase [Streptomyces avermitilis MA-4680]; ZP_00225817.1| COG2890: Methylase of polypeptide chain release factors [Kineococcus radiotolerans SRS30216]). TIGRFam: hemK_fam: modification methylase, HemK; Function unclear; putative methyltransferase 1894205..1895071 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173086 YP_001222416.1 CDS xysA NC_009480.1 1895220 1896515 D Endo-1,4-beta-xylanase precursor (ZP_00191610.3| COG3693: Beta-1,4-xylanase [Kineococcus radiotolerans SRS30216]; NP_242986.1| alkaline xylanase A (1,4-beta-D-xylan xylanohydrolase) [Bacillus halodurans C-125]). pfam00331, Glyco_hydro_10, Glycosyl hydrolase family 10.; High confidence in function and specificity; endo-1,4-beta-xylanase A 1895220..1896515 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173142 YP_001222417.1 CDS xysB NC_009480.1 1896686 1898695 D Endo-14-beta-xylanase precursor (ZP_00191610.3| COG3693: Beta-1,4-xylanase [Kineococcus radiotolerans SRS30216]; T30910 xylanase (EC 3.2.1.-) - Caldocellum saccharolyticum). pfam02018, CBM_4_9, Carbohydrate binding domain. pfam00331, Glyco_hydro_10, Glycosyl hydrolase family 10. pfam02494, HYR, HYR domain.; High confidence in function and specificity; endo-1,4-beta-xylanase A 1896686..1898695 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174317 YP_001222418.1 CDS CMM_1675 NC_009480.1 1899661 1900137 R hypothetical protein complement(1899661..1900137) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174350 YP_001222419.1 CDS CMM_1676 NC_009480.1 1900245 1900733 D hypothetical protein 1900245..1900733 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173092 YP_001222420.1 CDS CMM_1677 NC_009480.1 1900871 1901752 D conserved hypothetical protein (NP_721208.1| conserved hypothetical protein [Streptococcus mutans UA159]; ZP_00056756.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Thermobifida fusca]).; Function unclear; hypothetical protein 1900871..1901752 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173107 YP_001222421.1 CDS CMM_1678 NC_009480.1 1901811 1902281 R conserved hypothetical protein (ZP_00096355.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Novosphingobium aromaticivorans]; NP_629734.1| conserved hypothetical protein SC2E1.17 [Streptomyces coelicolor A3(2)]). pfam00293, NUDIX, NUDIX domain. mutt: mutator mutT protein; Function unclear; putative mutT-like protein complement(1901811..1902281) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173146 YP_001222422.1 CDS CMM_1679 NC_009480.1 1902278 1904365 R conserved hypothetical protein, ; NP_924649.1| probable peptidase [Gloeobacter violaceus]). pfam01738,DLH, Dienelactone hydrolase family.; Family membership; hypothetical protein complement(1902278..1904365) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173180 YP_001222423.1 CDS CMM_1680 NC_009480.1 1904405 1905184 R putative short chain dehydrogenase/oxidoreductase (ZP_00228097.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; NP_789380.1| putative oxidoreductase [Tropheryma whipplei TW08/27]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; short chain dehydrogenase complement(1904405..1905184) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173192 YP_001222424.1 CDS CMM_1681 NC_009480.1 1905363 1905680 D hypothetical protein 1905363..1905680 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173209 YP_001222425.1 CDS glpQ2 NC_009480.1 1905677 1906465 D putative glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) (ZP_00225962.1| COG0584: Glycerophosphoryl diester phosphodiesterase [Kineococcus radiotolerans SRS30216]; CAB09602.1| POSSIBLE GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE [Mycobacterium tuberculosis H37Rv]; NP_828103.1| putative glycerophosphoryl diester phosphodiesterase [Streptomyces avermitilis MA-4680]). GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE HYDROLYZES DEACYLATED PHOSPHOLIPIDS TO G3P AND THE CORRESPONDING ALCOHOLS. InterPro: Glycerophosphoryl diester phosphodiesterase pfam03009,GDPD, Glycerophosphoryl diester phosphodiesterase family. E. coli has two sequence related isozymes of glycerophosphoryl diester phosphodiesterase (GDPD) -periplasmic and cytosolic. This family also includes agrocinopine synthase, the similarity to GDPD has been noted. This family appears to have weak but not significant matches to mammalian phospholipase C pfam00388, which suggests that this family may adopt a TIM barrel fold.; Specificity unclear; putative glycerophosphoryl diester phosphodiesterase 1905677..1906465 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173266 YP_001222426.1 CDS CMM_1683 NC_009480.1 1906526 1906891 D conserved hypothetical protein (CAF21487.1| putative membrane-associated GTPase [Corynebacterium glutamicum ATCC 13032]; NP_216566.1| hypothetical protein Rv2050 [Mycobacterium tuberculosis H37Rv]).; hypothetical protein 1906526..1906891 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173798 YP_001222427.1 CDS CMM_1684 NC_009480.1 1906979 1908520 R putative apolipoprotein N-acyltransferase complement(1906979..1908520) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173288 YP_001222428.1 CDS CMM_1685 NC_009480.1 1908562 1911033 R putative helicase (NP_695922.1| probable helicase [Bifidobacterium longum NCC2705]; NP_625906.1| putative helicase [Streptomyces coelicolor A3(2)]). pfam00270,DEAD, DEAD/DEAH box helicase.; Family membership; putative helicase complement(1908562..1911033) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173303 YP_001222429.1 CDS tatC NC_009480.1 1911128 1911880 R Sec-independent twin-arginine protein translocase (ZP_00225800.1| COG0805: Sec-independent protein secretion pathway component TatC [Kineococcus radiotolerans SRS30216]; NP_787448.1| twin-arginine translocase TatC component [Tropheryma whipplei str. Twist]). pfam00902,TatC, Sec-independent protein translocase protein . The bacterial Tat system has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane.; High confidence in function and specificity; Sec-independent twin-arginine protein translocase complement(1911128..1911880) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173322 YP_001222430.1 CDS tatA NC_009480.1 1911935 1912279 R sec-independent twin-arginine protein translocase protein (Q10703|TATA_MYCTU Sec-independent protein translocase protein tatA/E homolog; P72267|TATA_RHOER Sec-independent protein translocase protein tatA/E homolog). pfam02416, MttA_Hcf106, mttA/Hcf106 family. Members of this protein family are involved in a sec independent translocation mechanism.; High confidence in function and specificity; sec-independent twin-arginine protein translocase protein complement(1911935..1912279) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173213 YP_001222431.1 CDS CMM_1688 NC_009480.1 1912477 1913466 R putative transcriptional regulator, DeoR family (ZP_00225803.1| COG2378: Predicted transcriptional regulator [Kineococcus radiotolerans SRS30216]; CAB04764.1| ORF11(1) [Rhodococcus erythropolis]).; Specificity unclear; DeoR family transcriptional regulator complement(1912477..1913466) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175908 YP_001222432.1 CDS CMM_1689 NC_009480.1 1913463 1914470 R putative transcriptional regulator (ZP_00225804.1| COG2378: Predicted transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_960766.1| hypothetical protein MAP1832c [Mycobacterium avium subsp. paratuberculosis str. k10]).; Specificity unclear; putative transcriptional regulator complement(1913463..1914470) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173367 YP_001222433.1 CDS CMM_1690 NC_009480.1 1914519 1915562 R Putative peptidyl-prolyl cis-trans isomerase (NP_787447.1| putative FKBP-type peptidyl-prolyl cis-trans isomerase [Tropheryma whipplei str. Twist]; NP_827862.1| putative FK-506 binding protein, peptidyl-prolyl cis-trans isomerase [Streptomyces avermitilis MA-4680]). pfam00254,FKBP_C, FKBP-type peptidyl-prolyl cis-trans isomerase.; Function unclear; putative peptidyl-prolyl cis-trans isomerase complement(1914519..1915562) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173382 YP_001222434.1 CDS CMM_1691 NC_009480.1 1915624 1916688 R putative methyltransferase (NP_625926.1| conserved hypothetical protein SCI41.34c [Streptomyces coelicolor A3(2)]; ZP_00199185.2| COG2519: tRNA(1-methyladenosine) methyltransferase and related methyltransferases [Kineococcus radiotolerans SRS30216]). pfam01135, PCMT,Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT). TIGRFam: pimt: protein-L-isoaspartate O-methyltr; Function unclear; putative methyltransferase complement(1915624..1916688) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173408 YP_001222435.1 CDS CMM_1692 NC_009480.1 1916685 1917380 R putative phosphatase (ZP_00047611.2| COG0637: Predicted phosphatase/phosphohexomutase [Magnetospirillum magnetotacticum]; ZP_00227166.1| COG0637: Predicted phosphatase/phosphohexomutase [Kineococcus radiotolerans SRS30216]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase.; Function unclear; putative phosphatase complement(1916685..1917380) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173435 YP_001222436.1 CDS CMM_1693 NC_009480.1 1917473 1918432 D conserved hypothetical protein (NP_625937.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00227165.1| hypothetical protein Krad06001765 [Kineococcus radiotolerans SRS30216]). pfam05601, DUF774,Protein of unknown function (DUF774). This family consists of several uncharacterised Actinomycete proteins of unknown function.; Family membership; hypothetical protein 1917473..1918432 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173452 YP_001222437.1 CDS cysS2 NC_009480.1 1918448 1919728 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(1918448..1919728) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173441 YP_001222438.1 CDS bacA NC_009480.1 1919733 1920551 R phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(1919733..1920551) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173944 YP_001222439.1 CDS CMM_1696 NC_009480.1 1920594 1921904 R putative metallopeptidase, peptidase family M20A (ZP_00228596.1| COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Kineococcus radiotolerans SRS30216]; NP_625951.1| putative peptidase [Streptomyces coelicolor A3(2)]). pfam01546, Peptidase_M20, Peptidase family M20/M25/M40. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification.; Specificity unclear; hypothetical protein complement(1920594..1921904) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174520 YP_001222440.1 CDS corA1 NC_009480.1 1922243 1923259 D putative magnesium and cobalt transporter, MIT family (ZP_00226389.1| COG0598: Mg2+ and Co2+ transporters [Kineococcus radiotolerans SRS30216]; ZP_00292887.1| COG0598: Mg2+ and Co2+ transporters [Thermobifida fusca]). , pfam01544, CorA, CorA-like Mg2+ transporter protein.,InterPro: Magnesium and cobalt transport protein CorA.; Specificity unclear; Mg2+/Co2+ transporter 1922243..1923259 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173053 YP_001222441.1 CDS CMM_1698 NC_009480.1 1923304 1924269 D conserved hypothetical protein, putative UDP-glucose 4-epimerase (ZP_00227689.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; NP_107357.1| hypothetical protein mll6957 [Mesorhizobium loti MAFF303099]). pfam01370, Epimerase,NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Function unclear; putative nucleoside-diphosphate-sugar epimerase 1923304..1924269 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173183 YP_001222442.1 CDS dnaJ3 NC_009480.1 1924278 1925618 R putative chaperone (NP_787408.1| chaperone protein [Tropheryma whipplei str. Twist]; NP_785551.1| chaperone protein DnaJ [Lactobacillus plantarum WCFS1]). pfam00226,DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system.; Function unclear; curved DNA binding protein complement(1924278..1925618) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173502 YP_001222443.1 CDS CMM_1700 NC_009480.1 1925869 1926510 D glycine betaine/carnitine/choline ABC transport system permease protein (NP_627156.1| putative permease membrane component [Streptomyces coelicolor A3(2)]; CAD91243.1| hypothetical protein [Nonomuraea sp. ATCC 39727]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; glycine betaine/carnitine/choline ABC transporter permease 1925869..1926510 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173434 YP_001222444.1 CDS CMM_1701 NC_009480.1 1926503 1927792 D glycine betaine/carnitine/choline ABC transporter ATP-binding protein (NP_826323.1| putative ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]; NP_627157.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]). cd00267, ABC_ATPase, ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop andWalker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.; Specificity unclear; glycine betaine/carnitin ABC transporter ATP-binding protein 1926503..1927792 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173563 YP_001222445.1 CDS CMM_1702 NC_009480.1 1927789 1928556 D putative glycine/betaine/choline ABC transporter,permease (NP_627158.1| putative permease membrane component [Streptomyces coelicolor A3(2)]; CAD91241.1| hypothetical protein [Nonomuraea sp. ATCC 39727]); Specificity unclear; putative glycine/betaine/choline ABC transporter permease 1927789..1928556 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173582 YP_001222446.1 CDS CMM_1703 NC_009480.1 1928559 1929566 D putative glycine betaine/carnitine/choline ABC transporter, substrate-binding protein (Osmoprotectant-binding protein) (CAD91240.1| hypothetical protein [Nonomuraea sp. ATCC 39727]; NP_627159.1| putative permease binding-protein component [Streptomyces coelicolor A3(2)]). MEMBER OF A HIGH AFFINITY MULTICOMPONENT BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR GLYCINE, BETAINE, CARNITINE AND CHOLINE. pfam04069,OpuAC, Substrate binding domain of ABC-type glycine betaine transport system. Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation. This domain is often fused to the permease component of the transporter complex. Family members are often integral membrane proteins or predicted to be attached to the membrane by a lipid anchor. Glycine betaine is involved in protection from high osmolarity environments for example in Bacillus subtilis. The family member OpuBC is closely related, and involved in choline transport. Choline is necessary for the biosynthesis of glycine betaine. L-carnitine is important for osmoregulation in Listeria monocytogenes. Family also contains proteins binding l-proline (ProX),histidine (HisX) and taurine (TauA).; Specificity unclear; putative glycine/betaine ABC transportersubstrate-binding protein 1928559..1929566 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173610 YP_001222447.1 CDS CMM_1704 NC_009480.1 1929809 1931617 R putative helicase (NP_826317.1| hypothetical protein SAV5140 [Streptomyces avermitilis MA-4680]; ZP_00293999.1| COG1061: DNA or RNA helicases of superfamily II [Thermobifida fusca]). pfam00270, DEAD,DEAD/DEAH box helicase.; Specificity unclear; putative DNA or RNA helicase complement(1929809..1931617) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174107 YP_001222448.1 CDS CMM_1705 NC_009480.1 1931818 1933017 R putative acyl-CoA dehydrogenase (ZP_00281635.1| COG1960: Acyl-CoA dehydrogenases [Burkholderia fungorum LB400]; NP_396585.1| acyl-CoA dehydrogenase [Agrobacterium tumefaciens str. C58]). pfam02771, Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain. pfam02770, Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain. pfam00441, Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain.; Specificity unclear; putative acyl-CoA dehydrogenase complement(1931818..1933017) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173650 YP_001222449.1 CDS CMM_1706 NC_009480.1 1933069 1933920 R conserved hypothetical protein (ZP_00209207.1| COG2514: Predicted ring-cleavage extradiol dioxygenase [Magnetospirillum magnetotacticum]; NP_738598.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). containing two domains of pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; hypothetical protein complement(1933069..1933920) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173671 YP_001222450.1 CDS CMM_1707 NC_009480.1 1934046 1934837 D putative esterase (ZP_00293606.1| COG2755: Lysophospholipase L1 and related esterases [Thermobifida fusca]; NP_822814.1| hypothetical protein SAV1638 [Streptomyces avermitilis MA-4680]). pfam00657,Lipase_GDSL, GDSL-like Lipase/Acylhydrolase.; Function unclear; putative esterase 1934046..1934837 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173753 YP_001222451.1 CDS pbpX NC_009480.1 1934853 1936067 R putative D-alanyl-D-alanine carboxypeptidase (Penicillin-binding protein) (NP_787455.1| serine-type D-Ala-D-Ala carboxypeptidase [Tropheryma whipplei str. Twist]; AAC32488.1| penicillin binding protein PbpA [Streptomyces clavuligerus]). , pfam00768, Peptidase_S11,D-alanyl-D-alanine carboxypeptidase.; High confidence in function and specificity; D-alanyl-D-alanine carboxypeptidase complement(1934853..1936067) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173788 YP_001222452.1 CDS CMM_1709 NC_009480.1 1936064 1936873 R putative rRNA methylase (NP_696042.1| possible tRNA/rRNA methyltransferase [Bifidobacterium longum NCC2705]; NP_827973.1| putative rRNA methylase [Streptomyces avermitilis MA-4680]). pfam00588,SpoU_methylase, SpoU rRNA Methylase family. This family of proteins probably use S-AdoMet.; Specificity unclear; hypothetical protein complement(1936064..1936873) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175525 YP_001222453.1 CDS CMM_1710 NC_009480.1 1937030 1937884 D putative NAD-dependent deacetylase, SIR2 family regulatory protein (NP_961194.1| hypothetical protein MAP2260 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_821712.1| putative Sir2-family regulator protein [Streptomyces avermitilis MA-4680]). Modulates the activities of several enzymes which are inactive in their acetylated form. pfam02146, SIR2, Sir2 family.; Specificity unclear; Sir2 family NAD-dependent protein deacetylase 1937030..1937884 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173807 YP_001222454.1 CDS CMM_1711 NC_009480.1 1937881 1938516 D putative phosphoglycerate mutase (ZP_00272306.1| COG0406: Fructose-2,6-bisphosphatase [Ralstonia metallidurans CH34]; ZP_00189764.2| COG0406: Fructose-2,6- bisphosphatase [Kineococcus radiotolerans SRS30216]). pfam00300, PGAM, Phosphoglycerate mutase family.; Specificity unclear; phosphoglycerate mutase 1937881..1938516 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173875 YP_001222455.1 CDS CMM_1712 NC_009480.1 1938570 1939664 R putative mannosyltransferase, glycosyl transferase family 1 (NP_780975.1| mannosyltransferase [Clostridium tetani E88]; NP_254135.1| glycosyltransferase WbpY [Pseudomonas aeruginosa PA01]). pfam00534,Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Specificity unclear; glycosyl transferase family protein complement(1938570..1939664) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173953 YP_001222456.1 CDS CMM_1713 NC_009480.1 1939661 1940557 R putative hydrolase (NP_249520.1| probable hydrolase [Pseudomonas aeruginosa PA01]; NP_824268.1| putative hydrolase [Streptomyces avermitilis MA-4680]). pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase complement(1939661..1940557) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173980 YP_001222457.1 CDS CMM_1714 NC_009480.1 1940695 1942416 D putative trehalose synthase (Maltose alpha-D-glucosyltransferase) (ZP_00228506.1| COG0366: Glycosidases [Kineococcus radiotolerans SRS30216]; NP_823979.1| putative trehalose synthase [Streptomyces avermitilis MA-4680]). pfam00128, Alpha-amylase, Alpha amylase, catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases.; Specificity unclear; putative trehalose synthase 1940695..1942416 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173964 YP_001222458.1 CDS dnaQ NC_009480.1 1942427 1943128 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1942427..1943128 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174034 YP_001222459.1 CDS rpmE2 NC_009480.1 1943205 1943462 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(1943205..1943462) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174780 YP_001222460.1 CDS modF NC_009480.1 1943594 1944388 R putative molybdate ABC transporter ATP-binding protein (NP_827656.1| putative ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]; ZP_00192057.2| COG1119: ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Kineococcus radiotolerans SRS30216]). pfam00005,ABC_tran, ABC transporter.; Specificity unclear; putative molybdate ABC transporter ATP-binding subunit complement(1943594..1944388) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174182 YP_001222461.1 CDS CMM_1718 NC_009480.1 1944470 1945654 R putative glycosyl transferase (ZP_00228927.1| COG0438: Glycosyltransferase [Kineococcus radiotolerans SRS30216]; ZP_00120280.2| COG0438: Glycosyltransferase [Bifidobacterium longum DJO10A]). InterPro: Glycosyl transferases group 1 pfam00534, Glycos_transf_1, Glycosyl transferases group 1.; Function unclear; putative glycosyl transferase complement(1944470..1945654) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175376 YP_001222462.1 CDS glgC NC_009480.1 1945701 1946942 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1945701..1946942 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174018 YP_001222463.1 CDS serB2 NC_009480.1 1946939 1947637 D putative phosphoserine phosphatase (O-phosphoserine phosphohydrolase) (NP_696939.1| probable phosphoserine phosphatase [Bifidobacterium longum NCC2705]; ZP_00209254.1| COG0560: Phosphoserine phosphatase [Magnetospirillum magnetotacticum]). pfam00702, Hydrolase,haloacid dehalogenase-like hydrolase. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. serB: phosphoserine phosphatase SerB.; Specificity unclear; hypothetical protein 1946939..1947637 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173169 YP_001222464.1 CDS CMM_1721 NC_009480.1 1947658 1948614 R putative proteinkinase or phosphotransferase (ZP_00238793.1| putative protein kinase [Bacillus cereus G9241]; ZP_00305365.1| COG3173: Predicted aminoglycoside phosphotransferase [Novosphingobium aromaticivorans DSM 12444]). pfam01636, APH, Phosphotransferase enzyme family.; Function unclear; putative protein kinase complement(1947658..1948614) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174218 YP_001222465.1 CDS CMM_1722 NC_009480.1 1948638 1949348 R putative 3-oxoacyl-[acyl-carrier protein] reductase (ZP_00059542.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Thermobifida fusca]; NP_626084.1| probable 3-oxacyl-(acyl-carrier-protein) reductase [Streptomyces coelicolor A3(2)] ). pfam00106, adh_short,short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative 3-oxoacyl-[acyl-carrier protein] reductase complement(1948638..1949348) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174087 YP_001222466.1 CDS CMM_1723 NC_009480.1 1949468 1949923 D hypothetical protein (ZP_00228932.1| hypothetical protein Krad06000613 [Kineococcus radiotolerans SRS30216]; NP_827633.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; hypothetical protein 1949468..1949923 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174104 YP_001222467.1 CDS CMM_1724 NC_009480.1 1949920 1950177 D conserved hypothetical protein (YP_062125.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827632.1| hypothetical protein SAV6456 [Streptomyces avermitilis MA-4680]).; hypothetical protein 1949920..1950177 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174251 YP_001222468.1 CDS CMM_1725 NC_009480.1 1950174 1951019 D conserved membrane protein (ZP_00228934.1| COG3346: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_302130.1| conserved membrane protein [Mycobacterium leprae TN]).; Conserved hypothetical protein; hypothetical protein 1950174..1951019 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174294 YP_001222469.1 CDS CMM_1726 NC_009480.1 1951025 1952623 R putative ABC transporter ATP-binding protein (ZP_00228938.1| COG0488: ATPase components of ABC transporters with duplicated ATPase domains [Kineococcus radiotolerans SRS30216]; NP_827602.1| putative ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]). InterPro: AAA ATPase superfamily pfam00005,ABC_tran, ABC transporter (twice).; Function unclear; putative ABC transporter ATP-binding protein complement(1951025..1952623) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174306 YP_001222470.1 CDS CMM_1727 NC_009480.1 1952848 1953183 R conserved hypothetical protein (ZP_00228941.1| COG2151: Predicted metal-sulfur cluster biosynthetic enzyme [Kineococcus radiotolerans SRS30216]; NP_827507.1| hypothetical protein SAV6331 [Streptomyces avermitilis MA-4680]). pfam01883, DUF59, Domain of unknown function DUF59.; Function unclear; hypothetical protein complement(1952848..1953183) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174389 YP_001222471.1 CDS CMM_1728 NC_009480.1 1953180 1953950 R putative ABC transporter, ATP-binding protein,putatively involved in Fe-S cluster assembly (YP_062121.1| multidrug Resistance Exporter [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228942.1| COG0396: ABC-type transport system involved in Fe-S cluster assembly, ATPase component [Kineococcus radiotolerans SRS30216]). pfam00005,ABC_tran, ABC transporter. InterPro: ABC transporter.; Function unclear; putative ABC transporter ATP-binding protein complement(1953180..1953950) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174413 YP_001222472.1 CDS CMM_1729 NC_009480.1 1953964 1954284 R putative 2Fe-2S ferredoxin (YP_062120.1| benzene 1,2-dioxygenase, ferredoxin protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787463.1| dioxygenase ferredoxin subunit [Tropheryma whipplei str. Twist]). pfam00355,Rieske, Rieske [2Fe-2S] domain. The rieske domain has a [2Fe-2S] centre. Two conserved cysteines that one Fe ion while the other Fe ion is coordinated by two conserved histidines. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit; Specificity unclear; putative 2Fe-2S ferredoxin complement(1953964..1954284) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174463 YP_001222473.1 CDS CMM_1730 NC_009480.1 1954281 1955504 R conserved hypothetical protein (YP_062119.1| ABC transporter, membrane component [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827502.1| hypothetical protein SAV6326 [Streptomyces avermitilis MA-4680]). pfam01458,UPF0051, Uncharacterized protein family (UPF0051).; hypothetical protein complement(1954281..1955504) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174499 YP_001222474.1 CDS CMM_1731 NC_009480.1 1955505 1956923 R conserved hypothetical protein (NP_626190.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00228944.1| COG0719: ABC-type transport system involved in Fe-S cluster assembly, permease component [Kineococcus radiotolerans SRS30216]). pfam01458, UPF0051,Uncharacterized protein family (UPF0051). InterPro: Uncharacterized protein family UPF0051.; hypothetical protein complement(1955505..1956923) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175317 YP_001222475.1 CDS ctaA NC_009480.1 1957190 1958200 D conserved membrane protein, putative cytochrome oxidase assembly protein (YP_062117.1| cytochrome oxidase assembly protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789364.1| putative cytochrome synthase [Tropheryma whipplei TW08/27]). , pfam02628, COX15-CtaA,Cytochrome oxidase assembly protein. This is a family of integral membrane proteins.; High confidence in function and specificity; putative cytochrome oxidase assembly protein 1957190..1958200 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174541 YP_001222476.1 CDS ctaB NC_009480.1 1958420 1959340 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(1958420..1959340) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175889 YP_001222477.1 CDS tktA NC_009480.1 1959514 1961604 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1959514..1961604 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174267 YP_001222478.1 CDS talA NC_009480.1 1961759 1962874 D catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase 1961759..1962874 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175888 YP_001222479.1 CDS pgiA NC_009480.1 1962871 1964466 D putative glucose-6-phosphate isomerase (Phosphoglucose isomerase)(Phosphohexose isomerase) (YP_062113.1| glucose-6-phosphate isomerase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789360.1| glucose-6-phosphate isomerase [Tropheryma whipplei TW08/27]). pfam00342, PGI, Phosphoglucose isomerase. Phosphoglucose isomerase catalyses the interconversion of glucose-6-phosphate and fructose-6-phosphate.; High confidence in function and specificity; hypothetical protein 1962871..1964466 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175855 YP_001222480.1 CDS zwfA2 NC_009480.1 1964505 1966046 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1964505..1966046 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174825 YP_001222481.1 CDS opcA NC_009480.1 1966043 1967041 D putative glucose-6-P dehydrogenase effector (YP_062111.1| oxppcycle protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228950.1| COG3429: Glucose-6-P dehydrogenase subunit [Kineococcus radiotolerans SRS30216]).; High confidence in function and specificity; putative glucose-6-P dehydrogenase effector 1966043..1967041 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173887 YP_001222482.1 CDS pglA NC_009480.1 1967038 1967808 D putative 6-phosphogluconolactonase (ZP_00294052.1| COG0363: 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Thermobifida fusca]; Q9XAB7|6PGL_STRCO 6-phosphogluconolactonase (6PGL)). pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase.; High confidence in function and specificity; putative 6-phosphogluconolactonase 1967038..1967808 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175651 YP_001222483.1 CDS CMM_1740 NC_009480.1 1968002 1968370 R putative electron transport protein (Rieske iron-sulfur protein) (YP_062109.1| electron transport protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827476.1| putative electron transport protein [Streptomyces avermitilis MA-4680]).; Function unclear; putative electron transport protein complement(1968002..1968370) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174784 YP_001222484.1 CDS secG NC_009480.1 1968382 1968633 R putative protein-export membrane protein (YP_062108.1| protein-export membrane protein SecG [Leifsonia xyli subsp. xyli str. CTCB07]; NP_695892.1| protein- export membrane protein SecG [Bifidobacterium longum NCC2705]; AAG16895.1| SecG [Streptomyces lividans]). pfam03840, SecG, Preprotein translocase SecG subunit.; Conserved hypothetical protein; preprotein translocase subunit SecG complement(1968382..1968633) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174674 YP_001222485.1 CDS tpiA NC_009480.1 1968777 1969574 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(1968777..1969574) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175020 YP_001222486.1 CDS pgk NC_009480.1 1969571 1970785 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(1969571..1970785) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175555 YP_001222487.1 CDS gapA NC_009480.1 1970792 1971799 R putative glyceraldehyde 3-phosphate dehydrogenase (YP_062105.1| glyceraldehyde 3-phosphate dehydrogenase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228958.1| COG0057: Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Kineococcus radiotolerans SRS30216]). pfam00044, Gp_dh_N,Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain. GAPDH is a tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis. pfam02800, Gp_dh_C,Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain.; High confidence in function and specificity; glyceraldehyde 3-phosphate dehydrogenase complement(1970792..1971799) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174718 YP_001222488.1 CDS sodA NC_009480.1 1971927 1972553 R superoxide dismutase [Mn/Fe] (YP_062104.1| superoxide dismutase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198450.2| COG0605: Superoxide dismutase [Kineococcus radiotolerans SRS30216]). , pfam00081,Sod_Fe_N, Iron/manganese superoxide dismutases, alpha-hairpin domain. , pfam02777, Sod_Fe_C, Iron/manganese superoxide dismutases, C-terminal domain. , InterPro: Manganese and iron superoxide dismutase (SODM); High confidence in function and specificity; hypothetical protein complement(1971927..1972553) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175066 YP_001222489.1 CDS whiA NC_009480.1 1972722 1973702 R conserved hypothetical protein, whiA homolog (YP_062103.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228959.1| COG1481: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_335917.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]). WhiA maybe a regulator which is essential for sporulation in Streptomyces pfam02650, DUF199,Uncharacterized BCR, COG1481.; Function unclear; hypothetical protein complement(1972722..1973702) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175710 YP_001222490.1 CDS CMM_1747 NC_009480.1 1973732 1974607 R conserved hypothetical protein, putative kinase (YP_062102.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228961.1| COG1660: Predicted P-loop-containing kinase [Kineococcus radiotolerans SRS30216]; NP_626216.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam03668, ATP_bind_2, P-loop ATPase protein family.; Function unclear; hypothetical protein complement(1973732..1974607) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173681 YP_001222491.1 CDS uvrC NC_009480.1 1974683 1976611 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(1974683..1976611) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174518 YP_001222492.1 CDS uvrA NC_009480.1 1976611 1979532 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(1976611..1979532) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175593 YP_001222493.1 CDS uvrB NC_009480.1 1979615 1981681 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1979615..1981681) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173808 YP_001222494.1 CDS coaE NC_009480.1 1981691 1982305 R dephospho-CoA kinase (YP_062097.1| dephospho-CoA kinase [Leifsonia xyli subsp. xyli str. CTCB07]; Q82A24|COAE_STRAW Dephospho-CoA kinase (Dephosphocoenzyme A kinase)). Catalyzes the phosphorylation of the 3-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity). pfam01121, CoaE, Dephospho-CoA kinase.; High confidence in function and specificity; hypothetical protein complement(1981691..1982305) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173234 YP_001222495.1 CDS rpsA NC_009480.1 1982392 1983846 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(1982392..1983846) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173497 YP_001222496.1 CDS CMM_1753 NC_009480.1 1984033 1985712 R conserved hypothetical protein (YP_062095.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226344.1| COG4805: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). pfam05960, DUF885, Bacterial protein of unknown function (DUF885). This family consists of several hypothetical bacterial proteins several of which are putative membrane proteins.; Function unclear; hypothetical protein complement(1984033..1985712) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175747 YP_001222497.1 CDS CMM_1754 NC_009480.1 1985709 1986167 R PTS system, IIA component (YP_044170.1| PTS system,mannitol-specific IIA component [Staphylococcus aureus subsp. aureus MSSA476]; NP_244719.1| PTS system, mannitol-specific enzyme II, A component [Bacillus halodurans C-125]). , pfam00359, PTS_EIIA_2, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.; Specificity unclear; PTS system fructose-specific transporter subunit IIA/fpr complement(1985709..1986167) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174651 YP_001222498.1 CDS polA1 NC_009480.1 1986210 1988894 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(1986210..1988894) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174702 YP_001222499.1 CDS CMM_1756 NC_009480.1 1988948 1989382 D conserved hypothetical protein, putative thioesterase (ZP_00057601.1| COG2050: Uncharacterized protein, possibly involved in aromatic compounds catabolism [Thermobifida fusca]; ZP_00227222.1| COG2050: Uncharacterized protein, possibly involved in aromatic compounds catabolism [Kineococcus radiotolerans SRS30216]). pfam03061, 4HBT, Thioesterase superfamily. This family contains a wide variety of enzymes,principally thioesterases.; Function unclear; putative thioesterase 1988948..1989382 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173250 YP_001222500.1 CDS CMM_1757 NC_009480.1 1989422 1990030 R putative response regulator involved in antitermination (YP_062092.1| two-component system,regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291532.1| COG3707: Response regulator with putative antiterminator output domain [Thermobifida fusca]). cd00156, REC, Signal receiver domain. pfam03861,ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins.; Specificity unclear; putative response regulator involved in antitermination complement(1989422..1990030) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174778 YP_001222501.1 CDS pykA NC_009480.1 1990294 1991739 R pyruvate kinase (YP_062088.1| pyruvate kinase II [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225692.1| COG0469: Pyruvate kinase [Kineococcus radiotolerans SRS30216]). pfam00224, PK, Pyruvate kinase, barrel domain. pfam02887, PK_C, Pyruvate kinase, alpha/beta domain.; High confidence in function and specificity; hypothetical protein complement(1990294..1991739) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174900 YP_001222502.1 CDS gltD NC_009480.1 1991826 1993283 R glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta complement(1991826..1993283) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174454 YP_001222503.1 CDS gltB NC_009480.1 1993276 1997847 R glutamate synthase (NADPH), alpha subunit (CAG18963.1| putative glutamate synthase, large subunit [Photobacterium profundum]; BAA75929.1| glutamine 2-oxoglutarate aminotransferase large subunit [Corynebacterium glutamicum]). pfam04897, Glu_synth_NTN,Glutamate synthase amidotransferase domain. pfam04898,Glu_syn_central, Glutamate synthase central domain. pfam01645, Glu_synthase, Conserved region in glutamate synthase. The aligned region of these proteins contains a putative FMN binding site and Fe-S cluster. pfam01493,GXGXG, GXGXG motif. InterPro: Ferredoxin-dependent glutamate synthase; High confidence in function and specificity; glutamate synthase (NADPH) subunit alpha complement(1993276..1997847) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174215 YP_001222504.1 CDS CMM_1761 NC_009480.1 1997955 1998977 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(1997955..1998977) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174995 YP_001222505.1 CDS trpA NC_009480.1 1999049 1999861 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1999049..1999861) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174984 YP_001222506.1 CDS trpB NC_009480.1 1999858 2001072 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1999858..2001072) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174329 YP_001222507.1 CDS trpC NC_009480.1 2001069 2001845 R involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase complement(2001069..2001845) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175347 YP_001222508.1 CDS CMM_1765 NC_009480.1 2001845 2002087 R putative membrane protein (YP_062081.1| mambrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626301.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00226960.1| COG3125: Heme/copper-type cytochrome/quinol oxidase, subunit 4 [Kineococcus radiotolerans SRS30216]).; Hypothetical protein; hypothetical protein complement(2001845..2002087) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174800 YP_001222509.1 CDS CMM_1766 NC_009480.1 2002192 2002830 R conserved membrane protein (YP_062080.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226959.1| hypothetical protein Krad06002361 [Kineococcus radiotolerans SRS30216]; NP_827348.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; hypothetical protein complement(2002192..2002830) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175165 YP_001222510.1 CDS trpE1 NC_009480.1 2002830 2004389 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(2002830..2004389) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174895 YP_001222511.1 CDS hisI NC_009480.1 2004386 2004784 R PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase complement(2004386..2004784) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174907 YP_001222512.1 CDS hisF NC_009480.1 2004781 2005572 R catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF complement(2004781..2005572) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175146 YP_001222513.1 CDS hisG NC_009480.1 2005575 2006414 R long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase complement(2005575..2006414) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173666 YP_001222514.1 CDS hisE NC_009480.1 2006463 2006726 R catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase complement(2006463..2006726) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174010 YP_001222515.1 CDS CMM_1772 NC_009480.1 2006826 2007194 R putative peptidyl-prolyl cis-trans isomerase (AAF04134.1| FK506 binding protein [Mycobacterium smegmatis]; YP_061894.1| FKBP-type peptidyl-prolyl cis-trans isomerase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_737516.1| putative peptidylprolyl isomerase [Corynebacterium efficiens YS-314]). PPIases accelerate the folding of proteins. pfam00254, FKBP_C, FKBP-type peptidyl-prolyl cis-trans isomerase. InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase); High confidence in function and specificity; FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase) complement(2006826..2007194) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173657 YP_001222516.1 CDS rpeA NC_009480.1 2007229 2007897 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(2007229..2007897) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175070 YP_001222517.1 CDS CMM_1774 NC_009480.1 2007908 2009407 R putative rRNA cytosine-C5-methylase (SUN protein,FMU protein) (ZP_00057727.1| COG0144: tRNA and rRNA cytosine-C5-methylases [Thermobifida fusca]; ZP_00226945.1| COG0144: tRNA and rRNA cytosine-C5-methylases [Kineococcus radiotolerans SRS30216]). cd00620,Methyltransferase_Sun, N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. pfam01189,Nol1_Nop2_Sun, NOL1/NOP2/sun family.; Specificity unclear; putative rRNA cytosine-C5-methylases complement(2007908..2009407) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172977 YP_001222518.1 CDS fmtA NC_009480.1 2009404 2010321 R methionyl-tRNA formyltransferase (YP_062073.1| methionyl-tRNA formyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291734.1| COG0223: Methionyl-tRNA formyltransferase [Thermobifida fusca]). Modify the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP. pfam00551, Formyl_trans_N, Formyl transferase. pfam02911, Formyl_trans_C, Formyl transferase, C-terminal domain. fmt: methionyl-tRNA formyltransferase; High confidence in function and specificity; hypothetical protein complement(2009404..2010321) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175100 YP_001222519.1 CDS priA NC_009480.1 2010413 2012509 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(2010413..2012509) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173538 YP_001222520.1 CDS metK NC_009480.1 2012552 2013763 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(2012552..2013763) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174516 YP_001222521.1 CDS dfpA NC_009480.1 2013803 2015020 R catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(2013803..2015020) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174232 YP_001222522.1 CDS rpoZ NC_009480.1 2015099 2015368 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(2015099..2015368) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174266 YP_001222523.1 CDS gmkA NC_009480.1 2015417 2016325 R putative fusion protein guanylate kinase (GMP kinase)/integration host factor (IHF) (YP_062068.1| guanylate kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787491.1| guanylate kinase; integration host factor fusion protein [Tropheryma whipplei str. Twist]; Q827Q3|KGUA_STRAW Guanylate kinase (GMP kinase)). Essential for recycling GMP and indirectly cGMP. pfam00625, Guanylate_kin, Guanylate kinase. InterPro: Guanylate kinase.; High confidence in function and specificity; guanylate kinase complement(2015417..2016325) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174929 YP_001222524.1 CDS pyrF NC_009480.1 2016322 2017215 R putative orotidine 5-phosphate decarboxylase (OMP decarboxylase) (YP_062067.1| orotidine 5'-phosphate decarboxylase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226927.1| COG0284: Orotidine-5'- phosphate decarboxylase [Kineococcus radiotolerans SRS30216]). pfam00215, OMPdecase, Orotidine 5'-phosphate decarboxylase / HUMPS family.; High confidence in function and specificity; putative orotidine 5'-phosphate decarboxylase complement(2016322..2017215) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175680 YP_001222525.1 CDS carB NC_009480.1 2017212 2020502 R putative carbamoyl-phosphate synthase large subunit (CAG19020.1| putative carbamoylphosphate synthase large subunit [Photobacterium profundum]; AAB39256.1| carbamoylphosphate synthetase large subunit [Salmonella typhimurium]). pfam00289, CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain (twice). pfam02786, CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain (twice). pfam02787, CPSase_L_D3,Carbamoyl-phosphate synthetase large chain,oligomerisation domain. pfam02142, MGS, MGS-like domain. This domain composes the whole protein of methylglyoxal synthetase and the domain is also found in Carbamoyl phosphate synthetase (CPS) where it forms a regulatory domain that binds to the allosteric effector ornithine.; High confidence in function and specificity; putative carbamoyl-phosphate synthase large subunit complement(2017212..2020502) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174408 YP_001222526.1 CDS carA NC_009480.1 2020502 2021680 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(2020502..2021680) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175950 YP_001222527.1 CDS CMM_1784 NC_009480.1 2021677 2022204 R conserved hypothetical protein (NP_625765.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; YP_062064.1| hypothetical protein Lxx11080 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(2021677..2022204) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175045 YP_001222528.1 CDS pyrC NC_009480.1 2022201 2023613 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(2022201..2023613) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175183 YP_001222529.1 CDS pyrB NC_009480.1 2023610 2024566 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit complement(2023610..2024566) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173363 YP_001222530.1 CDS pyrR NC_009480.1 2024563 2025147 R regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase complement(2024563..2025147) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173722 YP_001222531.1 CDS acsA2 NC_009480.1 2025260 2027296 R putative acetyl-coenzyme A synthetase (Acetate--CoA ligase) (ZP_00190335.3| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Kineococcus radiotolerans SRS30216]; ZP_00293126.1| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Thermobifida fusca]; ACSA_STRAW Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme)). pfam00501, AMP-binding, AMP-binding enzyme.; Specificity unclear; acyl-coenzyme A synthetase complement(2025260..2027296) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174149 YP_001222532.1 CDS CMM_1789 NC_009480.1 2027371 2028234 R putative anion ABC transporter, permease component (ZP_00226717.1| COG0600: ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Kineococcus radiotolerans SRS30216]; ZP_00267258.1| COG0600: ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Pseudomonas fluorescens PfO-1]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative anion ABC transporter permease complement(2027371..2028234) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173080 YP_001222533.1 CDS CMM_1790 NC_009480.1 2028231 2029283 R putative anion ABC transporter, substrate-binding protein (ZP_00226718.1| COG0715: ABC-type nitrate/sulfonate/bicarbonate transport systems,periplasmic components [Kineococcus radiotolerans SRS30216]; NP_959079.1| hypothetical protein MAP0145 [Mycobacterium avium subsp. paratuberculosis str. k10]). InterPro: Bacterial extracellular solute-binding proteins family 3.; Specificity unclear; putative anion ABC transporter substrate-binding protein complement(2028231..2029283) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175125 YP_001222534.1 CDS CMM_1791 NC_009480.1 2029356 2030225 R putative anion ABC transporter, ATP-binding protein (NP_959078.1| hypothetical protein MAP0145 [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00226719.1| COG1116: ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Kineococcus radiotolerans SRS30216]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative anion ABC transporter ATP-binding protein complement(2029356..2030225) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175277 YP_001222535.1 CDS nusB NC_009480.1 2030333 2030746 R putative antitermination protein (ZP_00291753.1| COG0781: Transcription termination factor [Thermobifida fusca]; Q9KXR0|NUSB_STRCO N utilization substance protein B homolog (NusB protein)). pfam01029, NusB, NusB family. The NusB protein is involved in the regulation of rRNA biosynthesis by transcriptional antitermination. InterPro: Antitermination protein NusB; High confidence in function and specificity; putative antitermination protein complement(2030333..2030746) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175385 YP_001222536.1 CDS efpA NC_009480.1 2030750 2031313 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(2030750..2031313) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173872 YP_001222537.1 CDS aroQ NC_009480.1 2031425 2031865 R catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase complement(2031425..2031865) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175155 YP_001222538.1 CDS CMM_1795 NC_009480.1 2031898 2032683 R putative short-chain dehydrogenase/reductase (ZP_00226581.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; NP_830063.1| 3-oxoacyl-[acyl-carrier protein] reductase [Bacillus cereus ATCC 14579]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short-chain dehydrogenase/reductase complement(2031898..2032683) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174639 YP_001222539.1 CDS aroB NC_009480.1 2032680 2033813 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(2032680..2033813) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175319 YP_001222540.1 CDS aroK NC_009480.1 2033810 2034301 R shikimate kinase (YP_062054.1| shikimate kinase I [Leifsonia xyli subsp. xyli str. CTCB07]; P95014|AROK_MYCTU Shikimate kinase (SK)). pfam01202, SKI,Shikimate kinase.; High confidence in function and specificity; hypothetical protein complement(2033810..2034301) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173596 YP_001222541.1 CDS aroC NC_009480.1 2034304 2035542 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2034304..2035542) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175614 YP_001222542.1 CDS aroE NC_009480.1 2035631 2036521 R Shikimate 5-dehydrogenase (YP_062052.1| shikimate 5-dehydrogenase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_301440.1| putative shikimate 5-dehydrogenase [Mycobacterium leprae TN]). pfam01488, Shikimate_DH,Shikimate / quinate 5-dehydrogenase. aroE: shikimate 5-dehydrogenase; High confidence in function and specificity; hypothetical protein complement(2035631..2036521) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175766 YP_001222543.1 CDS CMM_1800 NC_009480.1 2036514 2037659 R putative aminodeoxychorismate lyase (YP_055887.1| aminodeoxychorismate lyase [Propionibacterium acnes KPA171202]; NP_787502.1| hypothetical protein TWT374 [Tropheryma whipplei str. Twist]). pfam02618, ADC_lyase,Aminodeoxychorismate lyase. This family contains several aminodeoxychorismate lyase proteins. Aminodeoxychorismate lyase is a pyridoxal 5'-phosphate-dependent enzyme that converts 4-aminodeoxy- chorismate to pyruvate and p-aminobenzoate, a precursor of folic acid in bacteria.; Function unclear; hypothetical protein complement(2036514..2037659) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174854 YP_001222544.1 CDS CMM_1801 NC_009480.1 2038024 2038509 R similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein complement(2038024..2038509) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175315 YP_001222545.1 CDS alaS NC_009480.1 2038509 2041166 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(2038509..2041166) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175401 YP_001222546.1 CDS CMM_1803 NC_009480.1 2041172 2041393 R hypothetical protein (YP_062048.1| Hypothetical protein Lxx10900 [Leifsonia xyli subsp. xyli str. CTCB07]; CAD47949.1| hypothetical protein [Arthrobacter nicotinovorans]).; hypothetical protein complement(2041172..2041393) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173606 YP_001222547.1 CDS rpsD NC_009480.1 2041576 2042205 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(2041576..2042205) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175862 YP_001222548.1 CDS CMM_1805 NC_009480.1 2042454 2043875 R putative ATPase (YP_062045.1| ATPase related to the helicase subunit [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291928.1| COG2256: ATPase related to the helicase subunit of the Holliday junction resolvase [Thermobifida fusca]). pfam00004, AAA, ATPase family associated with various cellular activities (AAA).; Function unclear; recombination factor protein RarA complement(2042454..2043875) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174270 YP_001222549.1 CDS CMM_1807 NC_009480.1 2044467 2045699 D conserved hypothetical protein, putative ATPase (YP_062043.1| ATPase involved in DNA repair [Leifsonia xyli subsp. xyli str. CTCB07]; NP_828017.1| hypothetical protein SAV6841 [Streptomyces avermitilis MA-4680]; ZP_00057393.1| COG0419: ATPase involved in DNA repair [Thermobifida fusca]). pfam03993, DUF349, Domain of Unknown Function (DUF349). This domain is found singly or as up to five tandem repeats in a small set of bacterial proteins (twice).; Function unclear; putative ATPase 2044467..2045699 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175796 YP_001222550.1 CDS CMM_1808 NC_009480.1 2045793 2046401 D hypothetical protein (YP_062042.1| Hypothetical protein Lxx10830 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00121330.2| hypothetical protein Blon021233 [Bifidobacterium longum DJO10A]).; hypothetical protein 2045793..2046401 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175746 YP_001222551.1 CDS relA NC_009480.1 2046388 2048637 R GTP pyrophosphokinase (ATP:GTP 3-pyrophosphotransferase) (ppGpp synthetase I) ((P)ppGpp synthetase) (YP_062041.1| GTP pyrophosphokinase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291937.1| COG0317: Guanosine polyphosphate pyrophosphohydrolases/ synthetases [Thermobifida fusca]). pfam01966, HD, HD domain. HD domains are metal dependent phosphohydrolases. pfam04607,RelA_SpoT, Region found in RelA / SpoT proteins. pfam02824, TGS, TGS domain. The TGS domain is named after ThrRS, GTPase, and SpoT. pfam01842, ACT, ACT domain. This family of domains generally have a regulatory role. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. InterPro: RelA/SpoT family protein spoT_relA: RelA/SpoT family protein; High confidence in function and specificity; GTP pyrophosphokinase complement(2046388..2048637) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175742 YP_001222552.1 CDS CMM_1810 NC_009480.1 2048776 2049135 R conserved hypothetical protein (YP_062040.1| thiosulfate sulfurtransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293320.1| COG0607: Rhodanese-related sulfurtransferase [Thermobifida fusca]). pfam00581,Rhodanese, Rhodanese-like domain.; Family membership; hypothetical protein complement(2048776..2049135) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174264 YP_001222553.1 CDS secF NC_009480.1 2049132 2050142 R forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF complement(2049132..2050142) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175755 YP_001222554.1 CDS secD NC_009480.1 2050142 2051950 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(2050142..2051950) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175477 YP_001222555.1 CDS CMM_1813 NC_009480.1 2052077 2052460 R Region start changed from 2052547 to 2052460 (-87 bases); hypothetical protein complement(2052077..2052460) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174548 YP_001222556.1 CDS ruvB NC_009480.1 2052537 2053616 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(2052537..2053616) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175717 YP_001222557.1 CDS ruvA NC_009480.1 2053613 2054257 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(2053613..2054257) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174775 YP_001222558.1 CDS ruvC NC_009480.1 2054274 2054882 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(2054274..2054882) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173122 YP_001222559.1 CDS CMM_1817 NC_009480.1 2054934 2055701 R conserved hypothetical protein (YP_062033.1| Hypothetical protein Lxx10750 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00057401.1| COG0217: Uncharacterized conserved protein [Thermobifida fusca]; CAB10838.1| HIGHLY CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam01709, DUF28, Domain of unknown function DUF28. InterPro: Domain of unknown function DUF28.; Function unclear; hypothetical protein complement(2054934..2055701) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174390 YP_001222560.1 CDS CMM_1818 NC_009480.1 2055779 2056408 R with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT complement(2055779..2056408) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175677 YP_001222561.1 CDS CMM_1819 NC_009480.1 2056398 2057300 R with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS complement(2056398..2057300) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173840 YP_001222562.1 CDS CMM_1820 NC_009480.1 2057314 2057856 R conserved hypothetical protein (YP_062028.1| Hypothetical protein Lxx10700 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827999.1| putative HIT family protein [Streptomyces avermitilis MA-4680]). pfam01230, HIT, HIT domain. InterPro: HIT (Histidine triad) family; Family membership; hypothetical protein complement(2057314..2057856) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175655 YP_001222563.1 CDS thrS NC_009480.1 2057901 2059955 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase complement(2057901..2059955) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175631 YP_001222564.1 CDS CMM_1822 NC_009480.1 2060771 2061730 R putative transcriptional regulator, Cro/CI family (YP_056970.1| transcriptional regulator [Propionibacterium acnes KPA171202]; P39140|DEOR_BACSU Deoxyribonucleoside regulator). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. pfam04198, Sugar-bind, Putative sugar-binding domain. This probable domain is found in bacterial transcriptional regulators such as DeoR and SorC.; Specificity unclear; Cro/CI family transcriptional regulator complement(2060771..2061730) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174632 YP_001222565.1 CDS glpD NC_009480.1 2061839 2063599 D putative glycerol-3-phosphate dehydrogenase (NP_437021.1| putative glycerol-3-phosphate dehydrogenase protein [Sinorhizobium meliloti 1021]; NP_826180.1| putative glycerol-3-phosphate dehydrogenase [Streptomyces avermitilis MA-4680]). pfam01266, DAO, FAD dependent oxidoreductase. This family includes various FAD dependent oxidoreductases.; High confidence in function and specificity; putative glycerol-3-phosphate dehydrogenase 2061839..2063599 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175628 YP_001222566.1 CDS CMM_1824 NC_009480.1 2063716 2064207 D putative peroxidase (ZP_00293036.1| COG0386: Glutathione peroxidase [Thermobifida fusca]; ZP_00228459.1| COG0386: Glutathione peroxidase [Kineococcus radiotolerans SRS30216]; AAO68877.1| putative glutathione peroxidase; vitamin B12 transport periplasmic protein BtuE [Salmonella enterica subsp. enterica serovar Typhi Ty2]). pfam00255, GSHPx,Glutathione peroxidase. InterPro: Glutathione peroxidase; Specificity unclear; putative peroxidase 2063716..2064207 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175213 YP_001222567.1 CDS CMM_1825 NC_009480.1 2064253 2064768 R conserved hypothetical protein (ZP_00226621.1| hypothetical protein Krad06003015 [Kineococcus radiotolerans SRS30216]; NP_631325.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(2064253..2064768) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175621 YP_001222568.1 CDS CMM_1826 NC_009480.1 2064860 2065276 D conserved hypothetical protein (YP_062570.1| Hypothetical protein Lxx17000 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198676.1| COG3012: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). pfam02810, SEC-C, SEC-C motif. The SEC-C motif found in the C-terminus of the SecA protein, in the middle of some SWI2 ATPases and also solo in several proteins. The motif is predicted to chelate zinc with the CXC and C[HC] pairs that constitute the most conserved feature of the motif. It is predicted to be a potential nucleic acid binding domain. InterPro: SEC-C motif; hypothetical protein 2064860..2065276 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173867 YP_001222569.1 CDS CMM_1827 NC_009480.1 2065310 2066044 R putative PTS system hybrid protein (YP_061966.1| PTS system enzyme I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_415716.1| PTS hybrid protein; putative PTS family enzyme I and HPr components [Escherichia coli K12]). , , pfam03610, EIIA-man, PTS system fructose IIA component (N-terminal). , pfam00381, PTS-HPr, PTS HPr component phosphorylation site (C-terminal)., COG1925,FruB, Phosphotransferase system, HPr-related proteins (C-terminal)., InterPro: Phosphocarrier HPr protein , EIIA-man: PTS system fructose subfamil; Conserved hypothetical protein; putative PTS system hybrid protein complement(2065310..2066044) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175590 YP_001222570.1 CDS CMM_1828 NC_009480.1 2066041 2066694 R putative dihydroxyacetone kinase (YP_061965.1| dihydroxyacetone kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_782355.1| dihydroxyacetone kinase [Clostridium tetani E88]) pfam02734, Dak2, DAK2 domain. This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family. InterPro: Dak phosphatase domain; Function unclear; putative dihydroxyacetone kinase complement(2066041..2066694) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175596 YP_001222571.1 CDS CMM_1829 NC_009480.1 2066698 2067699 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(2066698..2067699) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175580 YP_001222572.1 CDS glpF NC_009480.1 2067981 2068733 D putative glycerol uptake facilitator protein, MIP family (YP_061539.1| glycerol uptake facilitator protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056969.1| glycerol uptake facilitator protein [Propionibacterium acnes KPA171202]). cd00333, MIP, Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water,small neutral molecules, and ions out of and between cells. InterPro: MIP family.; High confidence in function and specificity; MIP family glycerol uptake facilitator protein 2067981..2068733 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175565 YP_001222573.1 CDS glpK NC_009480.1 2068763 2070280 D putative glycerol kinase (ATP:glycerol 3-phosphotransferase) (YP_061540.1| glycerol kinase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056968.1| glycerol kinase 2 [Propionibacterium acnes KPA171202]). pfam00370, FGGY_N, FGGY family of carbohydrate kinases, N-terminal domain. pfam02782, FGGY_C, FGGY family of carbohydrate kinases, C-terminal domain.; High confidence in function and specificity; putative glycerol kinase 2068763..2070280 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175907 YP_001222574.1 CDS CMM_1832 NC_009480.1 2070370 2071101 R conserved hypothetical protein (ZP_00106310.2| COG2135: Uncharacterized conserved protein [Nostoc punctiforme PCC 73102]; NP_824216.1| hypothetical protein SAV3040 [Streptomyces avermitilis MA-4680]). pfam02586,DUF159, Uncharacterised ACR, COG2135.; hypothetical protein complement(2070370..2071101) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175821 YP_001222575.1 CDS trpD NC_009480.1 2071163 2072218 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(2071163..2072218) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175542 YP_001222576.1 CDS ctaE NC_009480.1 2072307 2072936 D putative cytochrome c oxidase subunit III (YP_061962.1| cytochrome C oxidase subunit III [Leifsonia xyli subsp. xyli str. CTCB07]; AAS20084.1| cytochrome-c oxidase chain III [Arthrobacter aurescens]; T35533 cytochrome-c oxidase (EC 1.9.3.1) chain III - Streptomyces coelicolor). pfam00510, COX3, Cytochrome c oxidase subunit III.; Specificity unclear; putative cytochrome c oxidase subunit III 2072307..2072936 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173909 YP_001222577.1 CDS qcrC NC_009480.1 2072963 2073763 D putative ubiquinol-cytochrome c reductase cytochrome c subunit (YP_061961.1| ubiquinol-cytochrome C reductase cytochrome C subunit [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789452.1| cytochrome C heme-binding subunit [Tropheryma whipplei TW08/27]). pfam00034,Cytochrom_C, Cytochrome c (twice).; Specificity unclear; putative ubiquinol-cytochrome c reductase cytochrome c subunit 2072963..2073763 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174852 YP_001222578.1 CDS qcrA NC_009480.1 2073809 2074918 D putative menaquinol-cytochrome C reductase iron-sulfur subunit (Rieske iron- sulfur protein)(YP_061960.1| Rieske iron-sulphur component of ubiQ-cytB reductase [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44345.1| ubiquinol-cytochrome c reductase iron-sulfur subunit [Tropheryma whipplei str. Twist]). pfam00355, Rieske,Rieske [2Fe-2S] domain. The rieske domain has a [2Fe-2S] centre.; High confidence in function and specificity; putative menaquinol-cytochrome C reductase iron-sulfur subunit 2073809..2074918 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173999 YP_001222579.1 CDS qcrB NC_009480.1 2074902 2076533 D putative menaquinol-cytochrome c reductase cytochrome B subunit (YP_061959.1| ubiquinol-cytochrome C reductase cytochrome B subunit [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44346.1| ubiquinol- cytochrome c reductase cytochrome b subunit [Tropheryma whipplei str. Twist]).; High confidence in function and specificity; putative menaquinol-cytochrome c reductase cytochrome B subunit 2074902..2076533 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173394 YP_001222580.1 CDS CMM_1838 NC_009480.1 2076648 2077565 D putative rRNA methylase involved in antibiotic resistance (AAD12162.1| tylosin resistance protein [Streptomyces fradiae]; MYRA_MICGR MYCINAMICIN-RESISTANCE PROTEIN MYRA [Micromonospora griseorubida]). assignment unsure, also weak similarity to COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis. hemK_rel_arch: methylase putative pfam01209,Ubie_methyltran, ubiE/COQ5 methyltransferase family (weak similarity).; Function unclear; putative rRNA methylase involved in antibiotic resistance 2076648..2077565 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175154 YP_001222581.1 CDS CMM_1839 NC_009480.1 2079396 2079833 R putative acetyltransferase (YP_002588.1| acetyltransferase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]; YP_048936.1| putative GNAT-family acetyltransferase [Erwinia carotovora subsp. atroseptica SCRI1043]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. InterPro: GCN5-related N-acetyltransferase.; Function unclear; putative acetyltransferase complement(2079396..2079833) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173667 YP_001222582.1 CDS CMM_1840 NC_009480.1 2079838 2080254 R conserved membrane protein (NP_301662.1| putative membrane protein [Mycobacterium leprae TN]; NP_626410.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). s1: malonate transporter MadL subunit; Conserved hypothetical protein; hypothetical protein complement(2079838..2080254) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175526 YP_001222583.1 CDS ctaD NC_009480.1 2080256 2082001 R putative cytochrome c oxidase subunit I (NP_827224.1| putative cytochrome c oxidase subunit I [Streptomyces avermitilis MA-4680]; ZP_00293766.1| COG0843: Heme/copper-type cytochrome/quinol oxidases,subunit 1 [Thermobifida fusca]). pfam00115, COX1,Cytochrome C and Quinol oxidase polypeptide I. InterPro: Cytochrome c oxidase subunit I.; High confidence in function and specificity; putative cytochrome c oxidase subunit I complement(2080256..2082001) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175495 YP_001222584.1 CDS ctaC NC_009480.1 2082014 2082925 R putative cytochrome c oxidase subunit II (Cytochrome AA3 subunit 2)(YP_062418.1| cytochrome C oxidase subunit II [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787371.1| cytochrome c oxidase subunit II [Tropheryma whipplei str. Twist]). pfam00116, COX2,Cytochrome C oxidase subunit II, periplasmic domain. InterPro: Cytochrome c oxidase subunit II.; High confidence in function and specificity; putative cytochrome c oxidase subunit II complement(2082014..2082925) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175246 YP_001222585.1 CDS CMM_1843 NC_009480.1 2083050 2083412 R conserved hypothetical protein (YP_062419.1| Hypothetical protein Lxx15060 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00354123.1| COG0316: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]). pfam01521, HesB, HesB-like domain. InterPro: Hypothetical hesB/yadR/yfhF family TIGR00049: HesB/YadR/YfhF family protein; hypothetical protein complement(2083050..2083412) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174724 YP_001222586.1 CDS CMM_1844 NC_009480.1 2083540 2084961 R putative metallopeptidase (YP_062420.1| peptidase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_961264.1| hypothetical protein MAP2330c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam01546, Peptidase_M20,Peptidase family M20/M25/M40. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. InterPro: Peptidase family M20/M25/M40; Family membership; hypothetical protein complement(2083540..2084961) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175460 YP_001222587.1 CDS CMM_1845 NC_009480.1 2085002 2085595 D putative membrane protein (YP_062421.1| Hypothetical protein Lxx15070 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00048249.2| hypothetical protein Magn021181 [Magnetospirillum magnetotacticum]; NP_626422.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]).; Conserved hypothetical protein; hypothetical protein 2085002..2085595 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175486 YP_001222588.1 CDS pyrD NC_009480.1 2085626 2086660 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(2085626..2086660) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175450 YP_001222589.1 CDS nrdR NC_009480.1 2086724 2087197 R putative transcriptional regulator (YP_062424.1| Hypothetical protein Lxx15110 [Leifsonia xyli subsp. xyli str. CTCB07]; CAE52895.1| regulatory protein [Streptomyces jumonjinensis]; NRDR_STRCL Putative regulatory protein nrdR). pfam03477, ATP-cone, ATP cone domain.; Function unclear; transcriptional regulator NrdR complement(2086724..2087197) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173040 YP_001222590.1 CDS hisD NC_009480.1 2087215 2088519 R catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase complement(2087215..2088519) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175424 YP_001222591.1 CDS CMM_1849 NC_009480.1 2088581 2089096 D putative flavin-dependent reductase/monooxygenase (YP_062426.1| flavin-dependent reductase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625377.1| putative flavin-dependent reductase [Streptomyces coelicolor A3(2)]; AAS77584.1| NADH-dependent FMN oxydoreductase [Rhodococcus sp. XP]). pfam01613, Flavin_Reduct, Flavin reductase like domain. This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components. InterPro: Flavin reductase-like domain.; Function unclear; putative flavin-dependent reductase/monooxygenase 2088581..2089096 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173626 YP_001222592.1 CDS dnaE NC_009480.1 2089128 2092640 R dnaE2; catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(2089128..2092640) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175422 YP_001222593.1 CDS CMM_1851 NC_009480.1 2092717 2093634 R putative 23S rRNa-specific pseudouridine synthase (YP_062428.1| ribosomal large subunit pseudouridine synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827309.1| putative ribosomal large subunit pseudouridine synthase [Streptomyces avermitilis MA-4680]). pfam01479, S4, S4 domain. pfam00849,PseudoU_synth_2, RNA pseudouridylate synthase. Members of this family are involved in modifying bases in RNA molecules.; Specificity unclear; putative pseudouridine synthase complement(2092717..2093634) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173331 YP_001222594.1 CDS CMM_1852 NC_009480.1 2093770 2094417 R putative cell division initiation protein (YP_062430.1| cell division initiation protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789188.1| putative cell division protein [Tropheryma whipplei TW08/27]; ZP_00226844.1| COG3599: Cell division initiation protein [Kineococcus radiotolerans SRS30216]). pfam05103, DivIVA,DivIVA protein.; Function unclear; cell division initiation protein complement(2093770..2094417) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175437 YP_001222595.1 CDS CMM_1853 NC_009480.1 2094564 2094869 R conserved membrane protein (YP_062431.1| Hypothetical protein Lxx15200 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291776.1| COG0762: Predicted integral membrane protein [Thermobifida fusca]).; Conserved hypothetical protein; hypothetical protein complement(2094564..2094869) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175937 YP_001222596.1 CDS CMM_1854 NC_009480.1 2094930 2095424 R conserved hypothetical protein (AAT89327.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00209988.1| COG1799: Uncharacterized protein conserved in bacteria [Magnetospirillum magnetotacticum MS-1]). pfam04472, DUF552, Protein of unknown function (DUF552). Family of uncharacterized proteins. cynS: cyanate lyase; hypothetical protein complement(2094930..2095424) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175244 YP_001222597.1 CDS CMM_1855 NC_009480.1 2095473 2096204 R conserved hypothetical protein (ZP_00291774.1| COG0325: Predicted enzyme with a TIM-barrel fold [Thermobifida fusca]; NP_827302.1| hypothetical protein SAV6126 [Streptomyces avermitilis MA-4680]). InterPro: Uncharacterized pyridoxal-5-phosphate dependent enzyme family UPF0001.; hypothetical protein complement(2095473..2096204) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174861 YP_001222598.1 CDS ftsZ NC_009480.1 2096201 2097340 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(2096201..2097340) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173827 YP_001222599.1 CDS ftsQ NC_009480.1 2097478 2098176 R putative cell division protein (NP_787358.1| cell division protein FtsQ [Tropheryma whipplei str. Twist]; ZP_00050269.2| COG1589: Cell division septal protein [Magnetospirillum magnetotacticum]). pfam03799, FtsQ, Cell division protein FtsQ.; Function unclear; cell division protein FtsQ complement(2097478..2098176) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174253 YP_001222600.1 CDS murC NC_009480.1 2098710 2100140 R putative UDP-N-acetylmuramate-alanine ligase (UDP-N- acetylmuramoyl- L-alanine synthetase) (YP_062436.1| UDP-N-acetylmuramate-alanine ligase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789469.1| UDP-N-acetylmuramate--alanine ligase [Tropheryma whipplei TW08/27]). pfam01225,Mur_ligase, Mur ligase family, catalytic domain. This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. pfam02875, Mur_ligase_C, Mur ligase family, glutamate ligase domain. InterPro: Cytoplasmic peptidoglycan synthetases N-terminal.; High confidence in function and specificity; putative UDP-N-acetylmuramate--alanine ligase complement(2098710..2100140) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174017 YP_001222601.1 CDS murG NC_009480.1 2100183 2101286 R UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase complement(2100183..2101286) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174124 YP_001222602.1 CDS ftsW2 NC_009480.1 2101283 2102572 R putative cell division membrane protein (YP_062438.1| cell division protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827297.1| putative cell division protein FtsW [Streptomyces avermitilis MA-4680]). pfam01098, FTSW_RODA_SPOVE, Cell cycle protein. InterPro: Cell cycle proteins.; High confidence in function and specificity; cell division membrane protein complement(2101283..2102572) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174503 YP_001222603.1 CDS murD NC_009480.1 2102529 2104073 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(2102529..2104073) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174091 YP_001222604.1 CDS mraY NC_009480.1 2104076 2105185 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(2104076..2105185) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174961 YP_001222605.1 CDS murF NC_009480.1 2105179 2106588 R putative UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase) (D-alanyl-D- alanine-adding enzyme)(YP_062441.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-alanyl ligase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626347.1| putative UDP-N-acetylmuramoylalanyl- D-glutamyl-2,6-diaminopimelate-D-alanyl-alanyl ligase [Streptomyces coelicolor A3(2)]). Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity). pfam01225, Mur_ligase, Mur ligase family,catalytic domain. pfam02875, Mur_ligase_C, Mur ligase family, glutamate ligase domain.; High confidence in function and specificity; putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase complement(2105179..2106588) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174579 YP_001222606.1 CDS murE NC_009480.1 2106590 2108134 R putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase (UDP-N-acetylmuramyl-tripeptide synthetase)(UDP-MurNAc-tripeptide synthetase) (YP_062442.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase [Leifsonia xyli subsp. xyli str. CTCB07]; Q82AE1|MURE_STRAW UDP-N-acetylmuramoylalanyl-D-glutamate- 2,6-diaminopimelate ligase (UDP-N-acetylmuramyl-tripeptide synthetase)). Cell wall formation. Diaminopimelic acid adding enzyme (By similarity). pfam01225, Mur_ligase, Mur ligase family, catalytic domain. pfam02875, Mur_ligase_C, Mur ligase family,glutamate ligase domain. InterPro: Cytoplasmic peptidoglycan synthetases N-terminal.; Specificity unclear; putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase complement(2106590..2108134) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175062 YP_001222607.1 CDS ftsI NC_009480.1 2108147 2109928 R putative peptidoglycan glycosyltransferase/penicillin-binding protein (Peptidoglycan glycosyltransferase 3) (Penicillin-binding protein 3) (YP_062443.1| penicillin binding protein,transpeptidase domain [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789476.1| penicillin-binding protein [Tropheryma whipplei TW08/27]). Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates. pfam03717, PBP_dimer, Penicillin-binding Protein dimerisation domain. This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. pfam00905, Transpeptidase,Penicillin binding protein transpeptidase domain. InterPro: Penicillin binding protein transpeptidase domain; High confidence in function and specificity; putative peptidoglycan glycosyltransferase/penicillin-binding protein complement(2108147..2109928) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174249 YP_001222608.1 CDS CMM_1866 NC_009480.1 2110020 2110694 R conserved hypothetical protein (YP_062444.1| Hypothetical protein Lxx15330 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626350.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(2110020..2110694) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173986 YP_001222609.1 CDS mraW NC_009480.1 2110691 2111647 R putative S-adenosyl-methyltransferase (YP_062445.1| S-adenosyl- methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; Q9S2W4|MRAW_STRCO S-adenosyl-methyltransferase mraW). pfam01795, Methyltransf_5, MraW methylase family. Members of this family are probably SAM dependent methyltransferases. InterPro: Methyltransferase family; Function unclear; S-adenosyl-methyltransferase MraW complement(2110691..2111647) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174097 YP_001222610.1 CDS mraZ NC_009480.1 2111751 2112182 R MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ complement(2111751..2112182) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175207 YP_001222611.1 CDS CMM_1869 NC_009480.1 2112521 2112916 R conserved membrane protein (YP_062447.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789481.1| putative membrane protein [Tropheryma whipplei TW08/27]; ZP_00057748.1| hypothetical protein [Thermobifida fusca]).; Conserved hypothetical protein; hypothetical protein complement(2112521..2112916) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174748 YP_001222612.1 CDS CMM_1870 NC_009480.1 2112994 2114115 D putative geranylgeranyl pyrophosphate synthetase (GGPP synthetase) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)] (YP_062448.1| geranylgeranyl pyrophosphate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225235.1| COG0142: Geranylgeranyl pyrophosphate synthase [Kineococcus radiotolerans SRS30216]). pfam00348, polyprenyl_synt,Polyprenyl synthetase. InterPro: Polyprenyl synthetase.; Specificity unclear; putative geranylgeranyl pyrophosphate synthase 2112994..2114115 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173954 YP_001222613.1 CDS CMM_1871 NC_009480.1 2114167 2114508 R conserved hypothetical protein, putative transcriptional regulator (YP_062449.1| Hypothetical protein Lxx15380 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_733557.1| putative transcriptional regulatory protein [Streptomyces coelicolor A3(2)]; ZP_00056758.1| hypothetical protein [Thermobifida fusca]).; putative transcriptional regulator complement(2114167..2114508) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174827 YP_001222614.1 CDS CMM_1872 NC_009480.1 2114721 2115992 D conserved hypothetical protein potentially involved in cell wall degradation (YP_062450.1| lipoprotein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_630954.1| putative secreted protein [Streptomyces coelicolor A3(2)]; NP_765874.1| autolysin (N-acetylmuramoyl-L-alanine amidase [Staphylococcus epidermidis ATCC 12228]). three LysM motifs are present: pfam01476, LysM, LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. InterPro: LysM motif pfam01476, LysM, LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.; Function unclear; hypothetical protein 2114721..2115992 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174922 YP_001222615.1 CDS pknE NC_009480.1 2116075 2118024 D putative eukaryotic-type serine/threonine protein kinase (YP_062451.1| serine/threonine kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787344.1| serine/threonine-protein kinase [Tropheryma whipplei str. Twist]; NP_827268.1| putative eukaryotic-type serine/threonine protein kinase [Streptomyces avermitilis MA-4680]). pfam00069, Pkinase, Protein kinase domain. pfam03793, PASTA, PASTA domain. This domain is found at the C termini of several Penicillin-binding proteins and bacterial serine/threonine kinases (thrice). InterPro: Eukaryotic protein kinase smart00220, S_TKc,Serine/Threonine protein kinases, catalytic domain; Phosphotransferases. Serine or threonine-specific kinase subfamily. pfam00069, Pkinase, Protein kinase domain.; Specificity unclear; putative serine/threonine protein kinase 2116075..2118024 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174278 YP_001222616.1 CDS aroG NC_009480.1 2118093 2119463 R putative phospho-2-dehydro-3-deoxyheptonate aldolase (Phospho-2- keto-3-deoxyheptonate aldolase) (YP_062452.1| 2-dehydro- 3-deoxyphosphoheptonate aldolase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827262.1| putative 2-dehydro-3-deoxyphosphoheptonate aldolase [Streptomyces avermitilis MA-4680]). pfam01474,DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyse the first step of the shikimate pathway.; High confidence in function and specificity; putative phospho-2-dehydro-3-deoxyheptonate aldolase complement(2118093..2119463) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173458 YP_001222617.1 CDS CMM_1875 NC_009480.1 2119523 2120212 R putative 1-acyl-sn-glycerol-3-phosphate acyltransferase (Lysophosphatidic acid acyltransferase) (YP_062453.1| 1-acylglycerol- 3-phosphate O-acyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827256.1| putative 1-acylglycerol-3-phosphate O-acyltransferase [Streptomyces avermitilis MA-4680]). ,pfam01553, Acyltransferase, Acyltransferase.; High confidence in function and specificity; putative acyltransferase complement(2119523..2120212) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175473 YP_001222618.1 CDS glkA NC_009480.1 2120291 2121256 R putative glucokinase, putative catabolite repressor (EC 2.7.1.2) (Glucose kinase) (NP_823156.1| putative sugar kinase [Streptomyces avermitilis MA-4680]; P40184|GLK_STRCO Glucokinase (Glucose kinase); NP_787341.1| glucokinase [Tropheryma whipplei str. Twist]). , REQUIRED FOR GLUCOSE REPRESSION OF MANY DIFFERENT GENES. , pfam00480, ROK, ROK family.; High confidence in function and specificity; putative glucokinase catabolite repressor complement(2120291..2121256) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175730 YP_001222619.1 CDS CMM_1877 NC_009480.1 2121390 2123216 D putative long-chain-fatty-acid-CoA ligase (Long-chain acyl-CoA synthetase) (YP_062455.1| long-chain-fatty-acid-CoA ligase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827245.1| putative acyl-CoA synthetase, long-chain-fatty-acid:CoA ligase [Streptomyces avermitilis MA-4680]). pfam00501, AMP-binding, AMP-binding enzyme. InterPro: AMP-dependent synthetase and ligase; Specificity unclear; putative long-chain-fatty-acid-CoA ligase 2121390..2123216 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173658 YP_001222620.1 CDS defB NC_009480.1 2123253 2123744 R putative polypeptide deformylase 2 (Polypeptide deformylase 2)(YP_062456.1| polypeptide deformylase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293948.1| COG0242: N-formylmethionyl-tRNA deformylase [Thermobifida fusca]). Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. pfam01327,Pep_deformylase, Polypeptide deformylase. pept_deformyl: polypeptide deformylase; High confidence in function and specificity; putative polypeptide deformylase complement(2123253..2123744) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174743 YP_001222621.1 CDS CMM_1879 NC_009480.1 2123779 2125251 R putative oxidoreductase (; AAO44726.1| pyridine nucleotide- disulphide oxidoreductase class I [Tropheryma whipplei str. Twist]). pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. 23387, pfam02852, Pyr_redox_dim,Pyridine nucleotide-disulphide oxidoreductase,dimerisation domain.; Function unclear; putative oxidoreductase ( E3 component of 2-oxoglutarate dehydrogenase complex) complement(2123779..2125251) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175135 YP_001222622.1 CDS pycA NC_009480.1 2125267 2128668 R biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase complement(2125267..2128668) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175423 YP_001222623.1 CDS CMM_1881 NC_009480.1 2128748 2129560 D putative ATPase (YP_062459.1| plasmid partitioning protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787759.1| putative plasmid partitioning protein [Tropheryma whipplei str. Twist]). InterPro: ParA family ATPase; Family membership; putative ATPase 2128748..2129560 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175539 YP_001222624.1 CDS CMM_1882 NC_009480.1 2129754 2130296 R putative transcriptional regulator, MerR family (YP_062460.1| Hypothetical protein Lxx15490 [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055792.1| predicted transcriptional regulator [Propionibacterium acnes KPA171202]). pfam00376, MerR, MerR family regulatory protein. InterPro: Bacterial regulatory proteins MerR family.; Specificity unclear; MerR family transcriptional regulator complement(2129754..2130296) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174525 YP_001222625.1 CDS CMM_1883 NC_009480.1 2130838 2131539 R putative transcriptional regulator, MerR family (YP_062461.1| Hypothetical protein Lxx15500 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_828158.1| hypothetical protein SAV6982 [Streptomyces avermitilis MA-4680]). pfam00376, MerR, MerR family regulatory protein. InterPro: Bacterial regulatory proteins MerR family.; Specificity unclear; MerR family transcriptional regulator complement(2130838..2131539) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175964 YP_001222626.1 CDS CMM_1884 NC_009480.1 2131539 2132021 R putative transcriptional regulator with FHA domain (YP_062462.1| Hypothetical protein Lxx15500 [Leifsonia xyli subsp. xyli str. CTCB07]; CAD67203.1| conserved hypothetical protein [Tropheryma whipplei TW08/27]; AAF07901.1| putative signal transduction protein GarA [Mycobacterium smegmatis]). InterPro: Forkhead-associated (FHA) domain; Function unclear; transcriptional regulator complement(2131539..2132021) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175299 YP_001222627.1 CDS dctA NC_009480.1 2132110 2133495 R putative Na+/H+-dicarboxylate symporter, DAACS family (NP_823991.1| putative sodium:dicarboxylate symporter [Streptomyces avermitilis MA-4680]; NP_601793.1| Na+/H+-dicarboxylate symporter [Corynebacterium glutamicum ATCC 13032]). pfam00375, SDF,Sodium:dicarboxylate symporter family.; Specificity unclear; Na+/H+-dicarboxylate symporter complement(2132110..2133495) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175831 YP_001222628.1 CDS dctS NC_009480.1 2133637 2135391 D putative two-component system sensor kinase (NP_629573.1| putative two-component sensor kinase [Streptomyces coelicolor A3(2)]; Q9RC53|CITS_BACHD Sensor protein citS). pfam00989, PAS, PAS domain. pfam02518,HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal sensory_box: PAS domain S-box; Specificity unclear; putative two-component system sensor kinase 2133637..2135391 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174812 YP_001222629.1 CDS dctR NC_009480.1 2135388 2136092 D putative two-component system response regulator (NP_629572.1| putative two-component response regulator [Streptomyces coelicolor A3(2)]; ZP_00198993.1| COG4565: Response regulator of citrate/malate metabolism [Kineococcus radiotolerans SRS30216]). cd00156, REC,Signal receiver domain. InterPro: Response regulator receiver domain; Specificity unclear; putative two-component system response regulator 2135388..2136092 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173879 YP_001222630.1 CDS CMM_1888 NC_009480.1 2136186 2137232 D putative zinc metalloprotease, family M4 (Q99132|PRT1_ERWCA Extracellular metalloprotease precursor; NP_626768.1| putative metalloprotease. [Streptomyces coelicolor A3(2)]). pfam02868,Peptidase_M4_C, Thermolysin metallopeptidase, alpha-helical domain. pfam01447, Peptidase_M4, Thermolysin metallopeptidase, catalytic domain. InterPro: Thermolysin metalloprotease (M4) family; Specificity unclear; zinc metalloprotease family M4 2136186..2137232 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174093 YP_001222631.1 CDS CMM_1889 NC_009480.1 2137233 2137514 D hypothetical protein (ZP_00413008.1| hypothetical protein ArthDRAFT_1891 [Arthrobacter sp. FB24]).; hypothetical protein 2137233..2137514 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175112 YP_001222632.1 CDS CMM_1890 NC_009480.1 2137511 2138371 D conserved hypothetical protein (YP_061831.1| Hypothetical protein Lxx08190 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_216549.1| hypothetical protein Rv2033c [Mycobacterium tuberculosis H37Rv]; ZP_00227509.1| hypothetical protein Krad06003896 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 2137511..2138371 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175860 YP_001222633.1 CDS CMM_1891 NC_009480.1 2138396 2139469 R putative transcriptional regulator, LacI family (CAB07149.1| TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LACI-FAMILY) [Mycobacterium tuberculosis H37Rv]; NP_940300.1| Putative LacI-family transcriptional regulator [Corynebacterium diphtheriae NCTC 13129]). pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family. smart00354,HTH_LACI, helix_turn _helix lactose operon repressor; Specificity unclear; hypothetical protein complement(2138396..2139469) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175805 YP_001222634.1 CDS CMM_1892 NC_009480.1 2139624 2140790 D putative polyamine ABC transporter, substrate binding protein (NP_627660.1| putative secreted protein [Streptomyces coelicolor A3(2)]; ZP_00130059.1| COG4134: ABC-type uncharacterized transport system, periplasmic component [Desulfovibrio desulfuricans G20]). pfam01547,SBP_bac_1, Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1.; Specificity unclear; putative polyamine ABC transporter substrate binding protein 2139624..2140790 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175599 YP_001222635.1 CDS CMM_1893 NC_009480.1 2140787 2141740 D putative polyamine ABC transporter, permease component (NP_827155.1| putative maltose permease [Streptomyces avermitilis MA-4680]; |NP_831069.1| Spermidine/putrescine transport system permease protein potB [Bacillus cereus ATCC 14579]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative polyamine ABC transporter permease 2140787..2141740 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175050 YP_001222636.1 CDS CMM_1894 NC_009480.1 2141740 2142555 D putative polyamine ABC transporter, permease component (CAG77144.1| ABC transporter permease protein [Erwinia carotovora subsp. atroseptica SCRI1043]; ZP_00126942.1| COG1177: ABC-type spermidine/putrescine transport system, permease component II [Pseudomonas syringae pv. syringae B728a]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative polyamine ABC transporter permease 2141740..2142555 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175238 YP_001222637.1 CDS CMM_1895 NC_009480.1 2142563 2143714 D putative polyamine ABC transporter, ATPase component (NP_579699.1| putative multiple sugar-binding transport ATP-binding protein [Pyrococcus furiosus DSM 3638]; ZP_00089377.1| COG3842: ABC-type spermidine/putrescine transport systems, ATPase components [Azotobacter vinelandii]). InterPro: AAA ATPase superfamily pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative polyamine ABC transporter ATPase 2142563..2143714 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175930 YP_001222638.1 CDS CMM_1896 NC_009480.1 2143711 2145303 D two-domain protein (Glycerophosphoryl diester phosphodiesterase, Inositol monophosphatase). N-terminal: COG0584, UgpQ, Glycerophosphoryl diester phosphodiesterase, pfam03009, GDPD, Glycerophosphoryl diester phosphodiesterase family (NP_823772.1| putative glycerophosphoryl diester phosphodiesterase [Streptomyces avermitilis MA-4680]; NP_622644.1| Glycerophosphoryl diester phosphodiesterase [Thermoanaerobacter tengcongensis]). C-terminal: COG0483, SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; pfam00459, Inositol_P,Inositol monophosphatase family (NP_699895.1| inositol monophosphatase family protein [Brucella suis 1330]; P44333|SUHB_HAEIN Inositol-1-monophosphatase (IMPase) (Inositol-1-phosphatase) (I-1-Pase)). Inositol-1-monophosphatase (EC 3.1.3.25) (IMPase) (Inositol-1-phosphatase) (I-1-Pase). InterPro: Inositol monophosphatase; High confidence in function and specificity; bifunctional glycerophosphoryl diester phosphodiesterase/inositol monophosphatase 2143711..2145303 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175841 YP_001222639.1 CDS CMM_1897 NC_009480.1 2145300 2146256 R NTP pyrophosphohydrolase complement(2145300..2146256) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175322 YP_001222640.1 CDS CMM_1898 NC_009480.1 2146297 2146776 D hypothetical protein 2146297..2146776 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174072 YP_001222641.1 CDS CMM_1899 NC_009480.1 2146817 2147833 R putative Zinc-dependant dehydrogenase (NP_962452.1| hypothetical protein MAP3518c [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_733654.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]). InterPro: Zinc-containing alcohol dehydrogenase superfamily pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Function unclear; putative Zinc-dependent dehydrogenase complement(2146817..2147833) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175830 YP_001222642.1 CDS CMM_1900 NC_009480.1 2147962 2148690 D conserved membrane protein (NP_832507.1| Integral membrane protein [Bacillus cereus ATCC 14579]; ZP_00227256.1| COG2324: Predicted membrane protein [Kineococcus radiotolerans SRS30216]).; Conserved hypothetical protein; hypothetical protein 2147962..2148690 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174365 YP_001222643.1 CDS CMM_1901 NC_009480.1 2148722 2149471 D hypothetical protein 2148722..2149471 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174327 YP_001222644.1 CDS CMM_1902 NC_009480.1 2149468 2150961 R putative amine oxidase (NP_746273.1| conserved hypothetical protein [Pseudomonas putida KT2440]; ZP_00225945.1| COG1231: Monoamine oxidase [Kineococcus radiotolerans SRS30216]). , pfam01593, Amino_oxidase,Flavin containing amine oxidoreductase.; Function unclear; hypothetical protein complement(2149468..2150961) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175867 YP_001222645.1 CDS CMM_1903 NC_009480.1 2151005 2151433 D putative RNA-binding heat shock protein (NP_626252.1| hypothetical protein [Streptomyces coelicolor A3(2)]; NP_601324.1| ribosome- associated heat shock protein [Corynebacterium glutamicum ATCC 13032]). smart00363, S4, S4 RNA-binding domain; Function unclear; putative heat shock protein 2151005..2151433 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174844 YP_001222646.1 CDS CMM_1904 NC_009480.1 2151430 2152398 R conserved hypothetical protein (ZP_00227630.1| hypothetical protein Krad06003512 [Kineococcus radiotolerans SRS30216]; NP_939566.1| Conserved hypothetical protein [Corynebacterium diphtheriae NCTC 13129]).; hypothetical protein complement(2151430..2152398) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174793 YP_001222647.1 CDS CMM_1905 NC_009480.1 2152491 2152925 D hypothetical protein 2152491..2152925 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174373 YP_001222648.1 CDS CMM_1906 NC_009480.1 2153147 2154175 D hypothetical protein 2153147..2154175 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175946 YP_001222649.1 CDS CMM_1907 NC_009480.1 2154219 2154473 D hypothetical protein 2154219..2154473 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174296 YP_001222650.1 CDS CMM_1908 NC_009480.1 2154561 2155541 R putative chaperone (ZP_00041700.1| COG2214: DnaJ-class molecular chaperone [Xylella fastidiosa Ann-1]; NP_111006.1| Molecular chaperone (DnaJ-related) [Thermoplasma volcanium GSS1]). InterPro: DnaJ N-terminal domain pfam00226, DnaJ, DnaJ domain.; Family membership; putative chaperone complement(2154561..2155541) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174404 YP_001222651.1 CDS cpsY NC_009480.1 2155538 2157205 R putative UDP-glucose-4-epimerase (NP_302449.1| probable UDP-glucose-4-epimerase [Mycobacterium leprae TN]; NP_630132.1| conserved hypothetical protein SC1C3.09 [Streptomyces coelicolor A3(2)]).; Function unclear; putative UDP-glucose-4-epimerase complement(2155538..2157205) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174903 YP_001222652.1 CDS CMM_1910 NC_009480.1 2157386 2158114 R hypothetical protein complement(2157386..2158114) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174234 YP_001222653.1 CDS CMM_1911 NC_009480.1 2158290 2159201 D putative dehydrogenase (NP_772800.1| blr6160 [Bradyrhizobium japonicum]; ZP_00228758.1| COG1319: Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Kineococcus radiotolerans SRS30216]). pfam00941, FAD_binding_5, FAD binding domain in molybdopterin dehydrogenase.; Function unclear; hypothetical protein 2158290..2159201 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174126 YP_001222654.1 CDS CMM_1912 NC_009480.1 2159198 2162083 D putative dehydrogenase (ZP_00228757.1| COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Kineococcus radiotolerans SRS30216]; NP_772801.1| blr6161 [Bradyrhizobium japonicum]). N-terminal: COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; pfam01799, Fer2_2, [2Fe-2S] binding domain. C-terminal: COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase,large subunit CoxL/CutL homologs; pfam01315, Ald_Xan_dh_C,Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain.; pfam02738, Ald_Xan_dh_C2, Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain (; Function unclear; hypothetical protein 2159198..2162083 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174139 YP_001222655.1 CDS CMM_1913 NC_009480.1 2162103 2163395 R putative amino acid permease, APC family (NP_336518.1| amino acid permease [Mycobacterium tuberculosis CDC1551]; NP_628774.1| putative amino acid transporter [Streptomyces coelicolor A3(2)]). InterPro: Amino acid permease pfam00324, AA_permease, Amino acid permease.; Specificity unclear; amino acid permease complement(2162103..2163395) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175031 YP_001222656.1 CDS CMM_1914 NC_009480.1 2163392 2164498 R conserved hypothetical protein (NP_823241.1| hypothetical protein SAV2065 [Streptomyces avermitilis MA-4680]; CAD47932.1| putative carbon monoxide dehydrogenase subunit F [Arthrobacter nicotinovorans]).; Function unclear; hypothetical protein complement(2163392..2164498) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175817 YP_001222657.1 CDS CMM_1915 NC_009480.1 2164684 2165313 D hypothetical protein 2164684..2165313 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175782 YP_001222658.1 CDS CMM_1916 NC_009480.1 2165363 2166028 D hypothetical protein 2165363..2166028 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174491 YP_001222659.1 CDS CMM_1917 NC_009480.1 2166240 2167694 D putative guanine deaminase (Guanine aminohydrolase) (NP_746397.1| guanine aminohydrolase [Pseudomonas putida KT2440]; P76641|GUAD_ECOLI Guanine deaminase (Guanase) (Guanine aminase) (Guanine aminohydrolase) (GAH)). pfam01979, Amidohydro_1, Amidohydrolase family. This family of enzymes are a a large metal dependent hydrolase superfamily.; Specificity unclear; guanine deaminase 2166240..2167694 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175881 YP_001222660.1 CDS CMM_1918 NC_009480.1 2167709 2168488 R putative membrane-associated acid phosphatase (ZP_00107252.1| COG0671: Membrane-associated phospholipid phosphatase [Nostoc punctiforme]; ZP_00052741.2| COG0671: Membrane-associated phospholipid phosphatase [Magnetospirillum magnetotacticum]). InterPro: PA-phosphatase related phosphoesterase smart00014, acidPPc,Acid phosphatase homologues pfam01569, PAP2, PAP2 superfamily.; Family membership; putative membrane-associated acid phosphatase complement(2167709..2168488) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174290 YP_001222661.1 CDS CMM_1919 NC_009480.1 2168485 2168853 R hypothetical protein complement(2168485..2168853) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174170 YP_001222662.1 CDS CMM_1920 NC_009480.1 2168921 2169544 D conserved hypothetical protein (ZP_00228764.1| COG2068: Uncharacterized MobA-related protein [Kineococcus radiotolerans SRS30216]; NP_630344.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; Function unclear; hypothetical protein 2168921..2169544 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174426 YP_001222663.1 CDS CMM_1921 NC_009480.1 2169552 2170271 R hypothetical protein complement(2169552..2170271) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175969 YP_001222664.1 CDS CMM_1922 NC_009480.1 2170402 2170863 R conserved hypothetical protein (ZP_00294077.1| COG0822: NifU homolog involved in Fe-S cluster formation [Thermobifida fusca]; NP_816042.1| NifU family protein [Enterococcus faecalis V583]). pfam01592, NifU_N, NifU-like N terminal domain. This domain is found in NifU in combination with pfam01106. This domain is found on isolated proteins in several bacterial species.; Function unclear; hypothetical protein complement(2170402..2170863) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174476 YP_001222665.1 CDS ggtA NC_009480.1 2170932 2172743 R putative gamma-glutamyltranspeptidase (ZP_00227294.1| COG0405: Gamma-glutamyltransferase [Kineococcus radiotolerans SRS30216]; NP_630062.1| putative transferase [Streptomyces coelicolor A3(2)]). g_glut_trans: gamma-glutamyltranspepti; High confidence in function and specificity; hypothetical protein complement(2170932..2172743) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175527 YP_001222666.1 CDS CMM_1924 NC_009480.1 2172845 2174284 D putative efflux MFS permease (NP_824729.1| putative integral membrane transport protein [Streptomyces avermitilis MA-4680]; ZP_00186259.2| COG0477: Permeases of the major facilitator superfamily [Rubrobacter xylanophilus DSM 9941]). pfam00083, Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters; Specificity unclear; putative efflux MFS permease 2172845..2174284 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175685 YP_001222667.1 CDS CMM_1925 NC_009480.1 2174382 2175410 D putative monooxygenase (NP_772138.1| blr5498 [Bradyrhizobium japonicum USDA 110]; ZP_00007886.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Rhodobacter sphaeroides]). pfam00296, Bac_luciferase, Luciferase-like monooxygenase.; Function unclear; putative monooxygenase/oxidoreductase 2174382..2175410 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174333 YP_001222668.1 CDS CMM_1926 NC_009480.1 2175523 2176338 D putative esterase (ZP_00220463.1| COG2755: Lysophospholipase L1 and related esterases [Burkholderia cepacia R1808]; NP_104793.1| hypothetical protein mlr3756 [Mesorhizobium loti MAFF303099]).; Function unclear; putative esterase 2175523..2176338 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174855 YP_001222669.1 CDS CMM_1927 NC_009480.1 2176335 2177027 D putative sugar kinase (ZP_00292020.1| COG0063: Predicted sugar kinase [Thermobifida fusca]; NP_771587.1| bll4947 [Bradyrhizobium japonicum]). pfam03853, YjeF_N,YjeF-related protein N-terminus.; Function unclear; hypothetical protein 2176335..2177027 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175220 YP_001222670.1 CDS CMM_1928 NC_009480.1 2177183 2177479 D Hypothetical protein; hypothetical protein 2177183..2177479 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173627 YP_001222671.1 CDS CMM_1929 NC_009480.1 2177572 2178600 R putative Zinc-dependant quinone oxidoreductase (NADPH:quinone reductase) (ZP_00190206.2| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_898787.1| putative quinone oxidoreductase [Rhodococcus erythropolis]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily.; High confidence in function and specificity; putative quinone oxidoreductase complement(2177572..2178600) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174926 YP_001222672.1 CDS CMM_1930 NC_009480.1 2178642 2180207 R conserved hypothetical protein (ZP_00121600.2| COG1574: Predicted metal-dependent hydrolase with the TIM-barrel fold [Bifidobacterium longum DJO10A]; ZP_00225851.1| COG1574: Predicted metal-dependent hydrolase with the TIM-barrel fold [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein complement(2178642..2180207) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175676 YP_001222673.1 CDS CMM_1931 NC_009480.1 2180204 2180872 R putative transcriptional regulator (NP_845841.1| protease synthase and sporulation negative regulatory protein PAI 2 [Bacillus anthracis str. Ames]; ZP_00118684.1| COG2808: Transcriptional regulator [Cytophaga hutchinsonii]). pfam04299, Neg_reg, Negative transcriptional regulator. In Bacillus subtilis, family member PAI 2 is involved in the negative regulation of protease synthesis and sporulation.; Specificity unclear; hypothetical protein complement(2180204..2180872) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173084 YP_001222674.1 CDS CMM_1932 NC_009480.1 2180987 2182702 R putative acyl-coenzyme A synthetase (ZP_00058202.1| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Thermobifida fusca]; NP_630298.1| putative acetyl-coenzyme A synthetase [Streptomyces coelicolor A3(2)]). InterPro: AMP-dependent synthetase and ligase pfam00501, AMP-binding, AMP-binding enzyme.; Specificity unclear; putative acyl-CoA synthetase complement(2180987..2182702) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174645 YP_001222675.1 CDS CMM_1933 NC_009480.1 2182827 2183663 D putative arylesterase (ZP_00228881.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Kineococcus radiotolerans SRS30216]; NP_832864.1| Arylesterase [Bacillus cereus ATCC 14579]). InterPro: Alpha/beta hydrolase fold pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative arylesterase 2182827..2183663 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174323 YP_001222676.1 CDS CMM_1934 NC_009480.1 2183722 2184069 R putative transcriptional regulator, LysR-family (AAN70636.1| transcriptional regulator, LysR family [Pseudomonas putida KT2440]; ZP_00091330.1| COG0583: Transcriptional regulator [Azotobacter vinelandii]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family.; Hypothetical protein; LysR family transcriptional regulator complement(2183722..2184069) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173853 YP_001222677.1 CDS CMM_1935 NC_009480.1 2184187 2184807 D putative pyrophosphohydrolase (NP_939379.1| Putative NUDIX-family hydrolase [Corynebacterium diphtheriae NCTC 13129]; NP_765595.1| mutator protein mutT [Staphylococcus epidermidis ATCC 12228]). pfam00293,NUDIX, NUDIX domain. also high similarity to: COG1051, ADP-ribose pyrophosphatase; Family membership; putative mutT-like hydrolase 2184187..2184807 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174940 YP_001222678.1 CDS CMM_1936 NC_009480.1 2184987 2185898 D putative lipase (gb|AAA53485.1| lipase precursor [Streptomyces albus]; ZP_00228194.1| COG4188: Predicted dienelactone hydrolase [Kineococcus radiotolerans SRS30216]). InterPro: Esterase/lipase/thioesterase family active site pfam01738, DLH, Dienelactone hydrolase family.; Family membership; putative lipase 2184987..2185898 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173726 YP_001222679.1 CDS CMM_1937 NC_009480.1 2186146 2187582 D putative membrane protein (CAA18059.1| PROBABLE CONSERVED TRANSMEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; ZP_00059568.1| COG2966: Uncharacterized conserved protein [Thermobifida fusca]). pfam06738, DUF1212, Protein of unknown function (DUF1212). This family represents a conserved region within a number of hypothetical proteins of unknown function found in eukaryotes, bacteria and archaea. Some family members are membrane proteins.; Family membership; hypothetical protein 2186146..2187582 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175875 YP_001222680.1 CDS CMM_1938 NC_009480.1 2187675 2188910 D putative peptidase, family M20D (NP_739352.1| putative peptidase [Corynebacterium efficiens YS-314]; NP_628283.1| peptidase [Streptomyces coelicolor A3(2)]). ,pfam01546, Peptidase_M20, Peptidase family M20/M25/M40. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification.; Specificity unclear; peptidase family M20D 2187675..2188910 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175216 YP_001222681.1 CDS CMM_1939 NC_009480.1 2188914 2189210 R putative transposase (NP_961542.1| hypothetical protein MAP2608 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_822059.1| putative transposase [Streptomyces avermitilis MA-4680])., ,pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome.; Family membership; IS481 family transposase complement(2188914..2189210) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174547 YP_001222682.1 CDS CMM_1940 NC_009480.1 2189210 2189917 R putative transposase (NP_961542.1| hypothetical protein MAP2608 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_628857.1| putative insertion element IS1652 transposase [Streptomyces coelicolor A3(2)]).; Family membership; IS481 family transposase complement(2189210..2189917) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174939 YP_001222683.1 CDS CMM_1941 NC_009480.1 2191227 2191718 R conserved membrane protein (NP_737704.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00209412.1| hypothetical protein Magn023696 [Magnetospirillum magnetotacticum]).; hypothetical protein complement(2191227..2191718) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175298 YP_001222684.1 CDS ppaG NC_009480.1 2191851 2192852 D conserved hypothetical protein, putative extracellular serine protease (NP_297821.1| hypothetical protein XF0531 [Xylella fastidiosa 9a5c]; NP_642686.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]).; Function unclear; putative extracellular serine protease 2191851..2192852 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174418 YP_001222685.1 CDS CMM_1943 NC_009480.1 2192928 2194061 R hypothetical protein complement(2192928..2194061) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174430 YP_001222686.1 CDS CMM_1944 NC_009480.1 2194058 2195218 R hypothetical protein complement(2194058..2195218) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174331 YP_001222687.1 CDS CMM_1945 NC_009480.1 2195319 2196569 R putative acyl-CoA dehydrogenase (ZP_00140036.1| COG1960: Acyl-CoA dehydrogenases [Pseudomonas aeruginosa UCBPP-PA14]; ZP_00226266.1| COG1960: Acyl-CoA dehydrogenases [Kineococcus radiotolerans SRS30216]).; Function unclear; putative acyl-CoA dehydrogenase complement(2195319..2196569) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174287 YP_001222688.1 CDS CMM_1946 NC_009480.1 2196566 2197936 R putative oxidoreductase/monooxygenase (ZP_00228688.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_794917.1| monooxygenase, DszA family [Pseudomonas syringae pv. tomato str. DC3000]).; Specificity unclear; putative oxidoreductase/monooxygenase complement(2196566..2197936) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174356 YP_001222689.1 CDS ppaH NC_009480.1 2198204 2199196 D putative extracellular serine protease (NP_779168.1| conserved hypothetical protein [Xylella fastidiosa Temecula1]; ZP_00293497.1| COG3591: V8-like Glu-specific endopeptidase [Thermobifida fusca]).; Function unclear; putative extracellular serine protease 2198204..2199196 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175461 YP_001222690.1 CDS ppaI NC_009480.1 2199308 2200276 D putative extracellular serine protease (NP_297821.1| hypothetical protein XF0531 [Xylella fastidiosa 9a5c]; NP_298723.1| hypothetical protein XF1434 [Xylella fastidiosa 9a5c]).; Conserved hypothetical protein; putative extracellular serine protease 2199308..2200276 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174360 YP_001222691.1 CDS CMM_1949 NC_009480.1 2200532 2202031 D putative shikimate MFS permease (ZP_00186986.1| COG0477: Permeases of the major facilitator superfamily [Rubrobacter xylanophilus DSM 9941]; NP_625306.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]; NP_756685.1| Shikimate transporter [Escherichia coli CFT073]). InterPro: General substrate transporters pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS permease 2200532..2202031 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174587 YP_001222692.1 CDS CMM_1950 NC_009480.1 2202084 2203658 R putative choline dehydrogenase (AAS99880.1| choline oxidase [Arthrobacter globiformis]; NP_828122.1| putative GMC-family oxidoreductase [Streptomyces avermitilis MA-4680]). InterPro: Glucose-methanol-choline (GMC) oxidoreductase pfam00732, GMC_oxred_N, GMC oxidoreductase. This family of proteins bind FAD as a cofactor. pfam05199,GMC_oxred_C, GMC oxidoreductase. This domain found associated with pfam00732.; Specificity unclear; putative oxidoreductase complement(2202084..2203658) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174371 YP_001222693.1 CDS CMM_1951 NC_009480.1 2203679 2205178 R putative betaine aldehyde dehydrogenase (EC 1.2.1.8) (NP_828124.1| putative betaine aldehyde dehydrogenase [Streptomyces avermitilis MA-4680]; NP_940508.1| betaine aldehyde dehydrogenase [Corynebacterium diphtheriae]). THIS IS A SOLUBLE NAD-DEPENDENT BETAINE ALDEHYDE-SPECIFIC DEHYDROGENASE. ESSENTIAL FOR THE UTILIZATION OF CHOLINE AS A PRECURSOR. InterPro: Aldehyde dehydrogenase family pfam00171, Aldedh,Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor.; Specificity unclear; putative glycine betaine aldehyde dehydrogenase complement(2203679..2205178) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175850 YP_001222694.1 CDS betT NC_009480.1 2205175 2207286 R high-affinity choline/glycine/betaine transport protein, BCCT family (CAG74648.1| high-affinity choline transport protein [Erwinia carotovora subsp. atroseptica SCRI1043]; NP_308387.1| high-affinity choline transport [Escherichia coli O157:H7]). High-affinity uptake of choline driven by a proton- motive force. InterPro: BCCT transporter pfam02028, BCCT, BCCT family transporter bcct: choline/carnitine/betaine transp; High confidence in function and specificity; BCCT family high-affinity choline/glycine/betaine transport protein complement(2205175..2207286) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175934 YP_001222695.1 CDS CMM_1953 NC_009480.1 2207514 2208182 R conserved hypothetical protein (ZP_00199506.1| hypothetical protein Krad06000279 [Kineococcus radiotolerans SRS30216]; NP_736786.1| hypothetical protein [Corynebacterium efficiens YS-314]).; hypothetical protein complement(2207514..2208182) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173344 YP_001222696.1 CDS CMM_1954 NC_009480.1 2208179 2208811 R conserved hypothetical protein (ZP_00199507.1| COG4950: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_792620.1| alkylhydroperoxidase AhpD domain protein [Pseudomonas syringae pv. tomato str. DC3000]; NP_773540.1| bll6900 [Bradyrhizobium japonicum]). InterPro: Alkylhydroperoxidase AhpD family core domain ahpD_dom: alkylhydroperoxidase AhpD famil; hypothetical protein complement(2208179..2208811) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175872 YP_001222697.1 CDS CMM_1955 NC_009480.1 2208808 2209464 R conserved hypothetical protein (ZP_00199507.1| COG4950: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_773541.1| bll6901 [Bradyrhizobium japonicum]). ahpD_dom: alkylhydroperoxidase AhpD fami; Function unclear; hypothetical protein complement(2208808..2209464) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174071 YP_001222698.1 CDS CMM_1956 NC_009480.1 2209461 2210534 R putative monooxygenase (YP_048200.1| putative monooxygenase [Erwinia carotovora subsp. atroseptica SCRI1043]; NP_822331.1| putative monooxygenase [Streptomyces avermitilis MA-4680]). pfam00296,Bac_luciferase, Luciferase-like monooxygenase. InterPro: Bacterial luciferase weak similaritiy to pfam00296,Bac_luciferase, Luciferase-like monooxygenase.; Function unclear; putative monooxygenase complement(2209461..2210534) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174684 YP_001222699.1 CDS CMM_1957 NC_009480.1 2210531 2212168 R putative peptide ABC transporter, ATP-binding protein (two fused ATPase domains; NP_601634.1| ABC-type transporter, duplicated ATPase component [Corynebacterium glutamicum ATCC 13032]; NP_789094.1| putative ABC transporter ATP-binding subunit [Tropheryma whipplei TW08/27]). InterPro: AAA ATPase superfamily.; Specificity unclear; putative peptide ABC transporter ATP-binding protein complement(2210531..2212168) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174212 YP_001222700.1 CDS CMM_1958 NC_009480.1 2212165 2213013 R putative peptide ABC transport system, permease component (YP_048202.1| ABC transporter permease protein [Erwinia carotovora subsp. atroseptica SCRI1043]; CAF21099.1| ABC-type dipeptide/oligopeptide/nickel transport systems, permease component [Corynebacterium glutamicum ATCC 13032]; NP_960023.1| hypothetical protein MAP1089 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative peptide ABC transport system, permease complement(2212165..2213013) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175795 YP_001222701.1 CDS CMM_1959 NC_009480.1 2213010 2213945 R putative peptide ABC transporter, permease component (NP_738943.1| putative transport protein [Corynebacterium efficiens YS-314]; YP_048203.1| ABC transporter permease protein [Erwinia carotovora subsp. atroseptica SCRI1043]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative peptide ABC transporter permease complement(2213010..2213945) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175149 YP_001222702.1 CDS CMM_1960 NC_009480.1 2213986 2215638 R putative peptide ABC transporter, substrate-binding protein (CAF21101.1| ABC-type dipeptide/oligopeptide/nickel transport systems, secreted component [Corynebacterium glutamicum ATCC 13032]; YP_048204.1| ABC-type transporter, substrate binding protein [Erwinia carotovora subsp. atroseptica SCRI1043]; NP_960020.1| hypothetical protein MAP1086 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00496,SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5. InterPro: Bacterial extracellular solute-binding protein family 5.; Specificity unclear; putative peptide ABC transporter substrate-binding protein complement(2213986..2215638) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175537 YP_001222703.1 CDS CMM_1961 NC_009480.1 2215852 2216343 D putative acetyltransferase (ZP_00191833.2| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Kineococcus radiotolerans SRS30216]; ZP_00182088.2| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Exiguobacterium sp. 255-15]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 2215852..2216343 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175197 YP_001222704.1 CDS clvE NC_009480.1 2216380 2217126 R conserved membrane protein (ZP_00099616.1| COG4200: Uncharacterized protein conserved in bacteria [Desulfitobacterium hafniense]; CAB60257.1| MrsE protein [Bacillus sp. HIL-Y85/54728]; NP_721536.1| putative transporter, trans-membrane domain bacteriocin immunity protein [Streptococcus mutans UA159]). PUTATIVE MEMBRANE PROTEIN INVOLVED IN LANTIBIOTIC IMMUNITY; Function unclear; hypothetical protein complement(2216380..2217126) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173849 YP_001222705.1 CDS clvG NC_009480.1 2217132 2217884 R conserved membrane protein (ZP_00099615.1| COG1277: ABC-type transport system involved in multi-copper enzyme maturation, permease component [Desulfitobacterium hafniense]; CAB60256.1| MrsG protein [Bacillus sp. HIL-Y85/54728]). PUTATIVELY INVOLVED IN IMMUNITY TO LANTIBIOTICS; Specificity unclear; hypothetical protein complement(2217132..2217884) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174003 YP_001222706.1 CDS clvF NC_009480.1 2217881 2218780 R putative ABC transporter, ATP-binding protein (CAB60255.1| MrsF protein [Bacillus sp. HIL-Y85/54728]; ZP_00099614.1| COG1131: ABC-type multidrug transport system, ATPase component [Desulfitobacterium hafniense]). PUTATIVELY INVOLVED IN IMMUNITY TO LANTIBIOTIC. pfam00005,ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative ABC transporter ATP-binding protein complement(2217881..2218780) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172928 YP_001222707.1 CDS clvR NC_009480.1 2218934 2219608 R putative two-component system, response regulator (NP_625929.1| putative two-component response regulator [Streptomyces coelicolor A3(2)]; ZP_00227053.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF LANTIOTIC pfam00072, Response_reg, Response regulator receiver domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family. InterPro: Response regulator receiver domain.; Specificity unclear; putative two-component system, response regulator complement(2218934..2219608) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173690 YP_001222708.1 CDS clvK NC_009480.1 2219605 2220741 R putative two-component system, sensor kinase (NP_825857.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; ZP_00228428.1| COG4585: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF LANTIBIOTIC InterPro: Histidine kinase-DNA gyrase B- phytochrome-like ATPase.; Specificity unclear; putative two-component system, sensor kinase complement(2219605..2220741) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172957 YP_001222709.1 CDS clvA NC_009480.1 2221103 2221309 D putative lantibiotic (clavicidin) precursor (LANA_ACTLG Lantibiotic actagardine (Gardimycin)). MAY INHIBIT PEPTIDOGLYCAN SYNTHESIS; Function unclear; putative lantibiotic 2221103..2221309 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173522 YP_001222710.1 CDS clvM NC_009480.1 2221401 2224562 D putative lantibiotic modifying protein (CAB60261.1| MrsM protein [Bacillus sp. HIL-Y85/54728]; CAD60521.1| CinM protein [Streptomyces cinnamoneus]). COULD BE IMPLICATED IN THE PROCESSING OR THE EXPORT PROCESS OF THE LANTIBIOTIC produced by Cmm_fin_1764. pfam05500, NisC,NisC-like family. Lantibiotics are peptide-derived, post-translationally modified antimicrobials produced by several bacterial strains.; Specificity unclear; putative lantibiotic modifying enzyme 2221401..2224562 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174819 YP_001222711.1 CDS CMM_1969 NC_009480.1 2224627 2225943 R hypothetical protein containing PASTA domain pfam03793, PASTA, PASTA domain. This domain is found at the C termini of several Penicillin-binding proteins and bacterial serine/threonine kinases. It binds the beta-lactam stem, which implicates it in sensing D-alanyl-D-alanine - the PBP transpeptidase substrate. InterPro: Proline-rich region.; Family membership; hypothetical protein complement(2224627..2225943) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173587 YP_001222712.1 CDS CMM_1970 NC_009480.1 2226073 2226537 R putative endonuclease (P50186|VSN1_NOCAE NaeI very-short-patch-repair endonuclease (V.NaeI); ZP_00149287.2| COG3727: DNA G:T-mismatch repair endonuclease [Methanococcoides burtonii DSM 6242]; ZP_00228987.1| COG3727: DNA G:T-mismatch repair endonuclease [Kineococcus radiotolerans SRS30216]). cd00221, Vsr, Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches. vsr: DNA mismatch endonuclease (vsr).; Specificity unclear; putative patch repair endonuclease complement(2226073..2226537) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174054 YP_001222713.1 CDS CMM_1971 NC_009480.1 2226747 2228012 R hypothetical protein complement(2226747..2228012) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174186 YP_001222714.1 CDS CMM_1972 NC_009480.1 2228593 2229132 R hypothetical membrane protein (NP_789466.1| putative integral membrane protein [Tropheryma whipplei TW08/27]).; Hypothetical protein; hypothetical protein complement(2228593..2229132) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174166 YP_001222715.1 CDS CMM_1973 NC_009480.1 2229419 2230750 D putative acyl-CoA dehydrogenase (ZP_00057322.1| COG1960: Acyl-CoA dehydrogenases [Thermobifida fusca]; XP_407376.1| hypothetical protein AN3239.2 [Aspergillus nidulans FGSC A4]; ZP_00226657.1| COG1960: Acyl-CoA dehydrogenases [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative acyl-CoA dehydrogenase 2229419..2230750 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174933 YP_001222716.1 CDS engA NC_009480.1 2230864 2232372 R synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(2230864..2232372) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174574 YP_001222717.1 CDS cmkA NC_009480.1 2232412 2233140 R putative cytidylate kinase (Cytidine monophosphate kinase) (YP_061643.1| cytidylate kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827698.1| putative cytidylate kinase [Streptomyces avermitilis MA-4680]). pfam02224, Cytidylate_kin, Cytidylate kinase. InterPro: Cytidylate kinase.; High confidence in function and specificity; putative cytidylate kinase complement(2232412..2233140) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175550 YP_001222718.1 CDS CMM_1976 NC_009480.1 2233137 2234213 R catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase complement(2233137..2234213) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175445 YP_001222719.1 CDS rluA NC_009480.1 2234252 2235112 R putative pseudouridine synthase (YP_061641.1| RNA pseudouridine synthase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056094.1| ribosomal large subunit pseudouridine synthase B [Propionibacterium acnes KPA171202]). pfam01479, S4, S4 domain. pfam00849,PseudoU_synth_2, RNA pseudouridylate synthase. Members of this family are involved in modifying bases in RNA molecules.; Family membership; putative pseudouridine synthase complement(2234252..2235112) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174444 YP_001222720.1 CDS CMM_1978 NC_009480.1 2235096 2235707 R conserved hypothetical protein, putative transcriptional regulator (YP_061640.1| Hypothetical protein Lxx05690 [Leifsonia xyli subsp. xyli str. CTCB07]; CAB52833.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam04079, DUF387,Putative transcriptional regulators (Ypuh-like). This family of conserved bacterial proteins are thought to possibly be helix-turn-helix type transcriptional regulators. potential Segregation and condensation protein B; Function unclear; putative transcriptional regulator complement(2235096..2235707) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173928 YP_001222721.1 CDS CMM_1979 NC_009480.1 2235697 2236494 R conserved hypothetical protein (YP_061639.1| Hypothetical protein Lxx05680 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00057587.1| COG1354: Uncharacterized conserved protein [Thermobifida fusca]; NP_626041.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). InterPro: DUF173 pfam02616, DUF173,Uncharacterised ACR, COG1354.; Function unclear; hypothetical protein complement(2235697..2236494) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174756 YP_001222722.1 CDS CMM_1980 NC_009480.1 2236550 2237434 R putative ATPase involved in partitioning (YP_061638.1| chromosome partitioning protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827684.1| putative partitioning or sporulation protein [Streptomyces avermitilis MA-4680]). pfam00991, ParA, ParA family ATPase. InterPro: ParA family ATPase; Function unclear; putative ATPase involved in partitioning complement(2236550..2237434) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173732 YP_001222723.1 CDS xerD NC_009480.1 2237504 2238490 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(2237504..2238490) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175373 YP_001222724.1 CDS CMM_1982 NC_009480.1 2238487 2239164 R putative NTP pyrophosphatase (YP_061636.1| NUDIX hydrolase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827681.1| putative ADP-ribose pyrophosphatase [Streptomyces avermitilis MA-4680]). pfam00293, NUDIX,NUDIX domain.; Function unclear; putative NTP pyrophosphatase complement(2238487..2239164) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174150 YP_001222725.1 CDS pyrG NC_009480.1 2239161 2240903 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(2239161..2240903) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174058 YP_001222726.1 CDS recN NC_009480.1 2240977 2242692 R putative DNA repair protein (Recombination protein N) (YP_061634.1| DNA repair protein RecN [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00294027.1| COG0497: ATPase involved in DNA repair [Thermobifida fusca]). pfam02463,SMC_N, RecF/RecN/SMC N terminal domain. This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini,and two extended coiled-coil domains separated by a hinge in the middle. pfam02483, SMC_C, SMC family, C-terminal domain. recN: DNA repair protein RecN; High confidence in function and specificity; putative DNA repair protein complement(2240977..2242692) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175407 YP_001222727.1 CDS ppnK NC_009480.1 2242685 2243602 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(2242685..2243602) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175487 YP_001222728.1 CDS CMM_1986 NC_009480.1 2243608 2244486 R putative rRNA methyltransferase (ZP_00294025.1| COG1189: Predicted rRNA methylase [Thermobifida fusca]; AAN24854.1| hemolysin-like protein with S4 domain found in bacteria and plants [Bifidobacterium longum NCC2705]). pfam01479, S4, S4 domain. Interpro: S4 domain. Interpro: Ribosomal RNA methyltransferase RrmJ/FtsJ.; Function unclear; hypothetical protein complement(2243608..2244486) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174256 YP_001222729.1 CDS CMM_1987 NC_009480.1 2244479 2244688 R hypothetical protein (YP_061679.1| Hypothetical protein Lxx06150 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(2244479..2244688) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175624 YP_001222730.1 CDS CMM_1988 NC_009480.1 2244698 2245738 R conserved hypothetical protein, putative hydrolase (YP_061321.1| 4-nitrophenylphosphatase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626059.1| hypothetical protein SCO1788 [Streptomyces coelicolor A3(2)]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase.; Function unclear; putative hydrolase complement(2244698..2245738) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175483 YP_001222731.1 CDS CMM_1989 NC_009480.1 2245728 2246708 R conserved hypothetical protein (ZP_00294017.1| COG0457: FOG: TPR repeat [Thermobifida fusca]; CAF21419.1| conserved hypothetical protein [Corynebacterium glutamicum ATCC 13032]).; hypothetical protein complement(2245728..2246708) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175668 YP_001222732.1 CDS tyrS NC_009480.1 2253555 2254859 R tyrosyl-tRNA synthetase (Tyrosine-tRNA ligase) (YP_061678.1| tyrosyl-tRNA synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827635.1| putative tyrosyl-tRNA synthetase [Streptomyces avermitilis MA-4680]). pfam00579, tRNA-synt_1b, tRNA synthetases class I (W and Y). pfam01479, S4, S4 domain.; High confidence in function and specificity; hypothetical protein complement(2253555..2254859) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173403 YP_001222733.1 CDS CMM_1991 NC_009480.1 2255079 2255786 D conserved hypothetical protein, putative DNA-binding protein (YP_061677.1| Hypothetical protein Lxx06130 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_939627.1| Putative DNA-binding protein [Corynebacterium diphtheriae NCTC 13129]).; hypothetical protein 2255079..2255786 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172970 YP_001222734.1 CDS CMM_1992 NC_009480.1 2255783 2256382 D putative membrane protein (YP_061675.1| Hypothetical protein Lxx06110 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_721449.1| conserved hypothetical protein, SatE [Streptococcus mutans UA159]).; hypothetical protein 2255783..2256382 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174776 YP_001222735.1 CDS CMM_1993 NC_009480.1 2256413 2257027 R responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase complement(2256413..2257027) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175290 YP_001222736.1 CDS CMM_1994 NC_009480.1 2257035 2257172 R hypothetical protein complement(2257035..2257172) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175839 YP_001222737.1 CDS argH NC_009480.1 2257169 2258662 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(2257169..2258662) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175086 YP_001222738.1 CDS argG NC_009480.1 2258667 2259905 R catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase complement(2258667..2259905) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173952 YP_001222739.1 CDS argF NC_009480.1 2259954 2260877 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase complement(2259954..2260877) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175478 YP_001222740.1 CDS argD NC_009480.1 2261027 2262244 R catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase complement(2261027..2262244) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175273 YP_001222741.1 CDS argB NC_009480.1 2262241 2263152 R catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase complement(2262241..2263152) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173913 YP_001222742.1 CDS argJ NC_009480.1 2263176 2264330 R bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase complement(2263176..2264330) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175093 YP_001222743.1 CDS argC NC_009480.1 2264327 2265376 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase complement(2264327..2265376) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175474 YP_001222744.1 CDS pheT NC_009480.1 2265506 2268049 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(2265506..2268049) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174077 YP_001222745.1 CDS pheS NC_009480.1 2268052 2269089 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(2268052..2269089) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174510 YP_001222746.1 CDS gluD NC_009480.1 2269218 2270042 R putative glutamate ABC transpoter, permease component (NP_738457.1| glutamate transporter permease protein GluD [Corynebacterium efficiens YS-314]; NP_823136.1| putative glutamate permease [Streptomyces avermitilis MA-4680]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative glutamate ABC transporter permease complement(2269218..2270042) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174542 YP_001222747.1 CDS gluC NC_009480.1 2270039 2270686 R putative glutamate ABC transpoter, permease component (NP_823137.1| putative glutamate permease [Streptomyces avermitilis MA-4680]; ZP_00293559.1| COG0765: ABC-type amino acid transport system, permease component [Thermobifida fusca]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative glutamate ABC transporter permease complement(2270039..2270686) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174617 YP_001222748.1 CDS gluB NC_009480.1 2270804 2271727 R putative glutamate ABC transporter, substrate-binding protein (NP_823138.1| putative glutamate periplasmic binding protein [Streptomyces avermitilis MA-4680]; ZP_00293560.1| COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/ domain [Thermobifida fusca]). pfam00497,SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3.; Specificity unclear; putative glutamate ABC transporter substrate-binding protein complement(2270804..2271727) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173167 YP_001222749.1 CDS gluA NC_009480.1 2271882 2272670 R putative glutamate ABC transporter, ATP-binding protein (NP_629902.1| glutamate uptake system ATP-binding protein [Streptomyces coelicolor A3(2)]; ZP_00293561.1| COG1126: ABC-type polar amino acid transport system,ATPase component [Thermobifida fusca]). InterPro: AAA ATPase superfamily; Specificity unclear; putative glutamate ABC transporter ATP-binding protein complement(2271882..2272670) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175388 YP_001222750.1 CDS CMM_2008 NC_009480.1 2272822 2273622 R putaive rRNA methyltransferase (YP_061662.1| rRNA methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625873.1| putative rRNA methylase [Streptomyces coelicolor A3(2)]). pfam00588,SpoU_methylase, SpoU rRNA Methylase family. This family of proteins probably use S-AdoMet.; Function unclear; putative rRNA methyltransferase complement(2272822..2273622) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174375 YP_001222751.1 CDS rplT NC_009480.1 2273685 2274077 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(2273685..2274077) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174142 YP_001222752.1 CDS rpmI NC_009480.1 2274124 2274318 R 50S ribosomal protein L35 (YP_062721.1| 50S ribosomal protein L35 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787293.1| 50S ribosomal protein L35 [Tropheryma whipplei str. Twist]). pfam01632,Ribosomal_L35p, Ribosomal protein L35.; High confidence in function and specificity; 50S ribosomal protein L35 complement(2274124..2274318) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173513 YP_001222753.1 CDS infC NC_009480.1 2274311 2274730 R translation initiation factor IF-3 (YP_062722.1| translation initiation factor IF-3 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625876.1| putative translation initiation factor IF-3 [Streptomyces coelicolor A3(2)]). IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. pfam05198, IF3_N, Translation initiation factor IF-3, N-terminal domain. pfam00707,IF3_C, Translation initiation factor IF-3, C-terminal domain.; High confidence in function and specificity; translation initiation factor IF-3 complement(2274311..2274730) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174138 YP_001222754.1 CDS CMM_2012 NC_009480.1 2275284 2275769 D hypothetical protein (ZP_00226864.1| COG0468: RecA/RadA recombinase [Kineococcus radiotolerans SRS30216]; NP_827912.1| hypothetical protein SAV6736 [Streptomyces avermitilis MA-4680]).; hypothetical protein 2275284..2275769 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174611 YP_001222755.1 CDS CMM_2013 NC_009480.1 2275809 2276576 R hypothetical protein (NP_625878.1| hypothetical protein SCI35.24c [Streptomyces coelicolor A3(2)]; ZP_00291747.1| hypothetical protein Tfus02002786 [Thermobifida fusca]).; Function unclear; hypothetical protein complement(2275809..2276576) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174569 YP_001222756.1 CDS hisA NC_009480.1 2276573 2277322 R catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; phosphoribosyl isomerase A complement(2276573..2277322) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175912 YP_001222757.1 CDS hisH NC_009480.1 2277386 2278027 R with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH complement(2277386..2278027) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173197 YP_001222758.1 CDS hisB NC_009480.1 2278024 2278632 R catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase complement(2278024..2278632) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174374 YP_001222759.1 CDS CMM_2017 NC_009480.1 2278745 2279143 R conserved membrane protein (ZP_00292498.1| COG0739: Membrane proteins related to metalloendopeptidases [Thermobifida fusca]; NP_337294.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]). weak similarity to: pfam01476, LysM, LysM domain. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function.; hypothetical protein complement(2278745..2279143) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173295 YP_001222760.1 CDS lexA NC_009480.1 2279505 2280185 D Represses a number of genes involved in the response to DNA damage; LexA repressor 2279505..2280185 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175173 YP_001222761.1 CDS hflX NC_009480.1 2280270 2281835 R putative GTP-binding protein (NP_629920.1| conserved hypothetical protein SC4H2.17 [Streptomyces coelicolor A3(2)]; ZP_00293571.1| COG2262: GTPases [Thermobifida fusca]). pfam00071, Ras, Ras family. Includes sub-families Ras, Rab, Rac, Ral, Ran, Rap Ypt1 and more. Shares P-loop motif with GTP_EFTU, arf and myosin_head.; Function unclear; putative GTP-binding protein complement(2280270..2281835) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173642 YP_001222762.1 CDS CMM_2020 NC_009480.1 2281876 2282502 D putative rRNA methylase (ZP_00226409.1| COG2813: 16S RNA G1207 methylase RsmC [Kineococcus radiotolerans SRS30216]; ZP_00120705.1| COG2813: 16S RNA G1207 methylase RsmC [Bifidobacterium longum DJO10A]). pfam01170, UPF0020, Putative RNA methylase family UPF0020.; Conserved hypothetical protein; hypothetical protein 2281876..2282502 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173133 YP_001222763.1 CDS dapF NC_009480.1 2282551 2283429 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(2282551..2283429) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174176 YP_001222764.1 CDS miaA NC_009480.1 2283439 2284362 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(2283439..2284362) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174179 YP_001222765.1 CDS miaB NC_009480.1 2284359 2285945 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(2284359..2285945) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175856 YP_001222766.1 CDS recX NC_009480.1 2285996 2286568 R putative recX, regulatory protein for recA activity (O50488|RECX_STRCO Regulatory protein recX; ZP_00058957.1| COG2137: Uncharacterized protein conserved in bacteria [Thermobifida fusca]). pfam02631, RecX, RecX family. RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.; Conserved hypothetical protein; hypothetical protein complement(2285996..2286568) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173198 YP_001222767.1 CDS recA NC_009480.1 2287165 2288253 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(2287165..2288253) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175940 YP_001222768.1 CDS CMM_2026 NC_009480.1 2288536 2288769 R conserved hypothetical protein (NP_961784.1| hypothetical protein MAP2850c [Mycobacterium avium subsp. paratuberculosis str. k10]; BAB99349.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032]).; hypothetical protein complement(2288536..2288769) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173414 YP_001222769.1 CDS CMM_2027 NC_009480.1 2288846 2289154 R putative transcriptional regulator, Cro/CI family (ZP_00293549.1| COG1396: Predicted transcriptional regulators [Thermobifida fusca]; H70878 probable regulator - Mycobacterium tuberculosis (strain H37RV)). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator complement(2288846..2289154) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173860 YP_001222770.1 CDS CMM_2028 NC_009480.1 2289294 2289818 R conserved hypothetical protein (ZP_00047717.1| COG1546: Uncharacterized protein (competence- and mitomycin-induced) [Magnetospirillum magnetotacticum]; NP_629879.1| conserved hypothetical protein SC7C7.09 [Streptomyces coelicolor A3(2)]). pfam02464, CinA,Competence-damaged protein. InterPro: Competence-damaged protein cinA_cterm: competence/damage-inducible p; Function unclear; hypothetical protein complement(2289294..2289818) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173810 YP_001222771.1 CDS pgsA NC_009480.1 2289815 2290441 R putative CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyl- transferase (NP_629878.1| phosphatidylglycerophosphate synthase [Streptomyces coelicolor A3(2)]; ZP_00058965.1| COG0558: Phosphatidyl-glycerophosphate synthase [Thermobifida fusca]). May catalyze the committed step to the synthesis of the acidic phospholipids. pfam01066, CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. InterPro: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Specificity unclear; hypothetical protein complement(2289815..2290441) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174975 YP_001222772.1 CDS ftsK NC_009480.1 2290445 2293300 R putative DNA translocase ftsK (Q82K93|FTSK_STRAW DNA translocase ftsK; ZP_00058968.1| COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins [Thermobifida fusca]). DNA motor protein which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind it. InterPro: FtsK/SpoIIIE family pfam01580, FtsK_SpoIIIE,FtsK/SpoIIIE family. FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids, termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif.; High confidence in function and specificity; cell division protein complement(2290445..2293300) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174649 YP_001222773.1 CDS CMM_2031 NC_009480.1 2293369 2294601 R putative ABC transporter, permease component (ZP_00198031.1| COG0577: ABC-type antimicrobial peptide transport system, permease component [Kineococcus radiotolerans SRS30216]; ZP_00048178.2| COG0577: ABC-type antimicrobial peptide transport system, permease component [Magnetospirillum magnetotacticum]). pfam02687, FtsX,Predicted permease. This is a family of predicted permeases and hypothetical transmembrane proteins).; Specificity unclear; putative ABC transporter permease complement(2293369..2294601) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174069 YP_001222774.1 CDS CMM_2032 NC_009480.1 2294598 2295305 R putative ABC transporter, ATPase component (ZP_00225680.1| COG1136: ABC-type antimicrobial peptide transport system, ATPase component [Kineococcus radiotolerans SRS30216]; NP_811407.1| ABC transporter,ATP-binding protein [Bacteroides thetaiotaomicron VPI-5482]). InterPro: AAA ATPase superfamily pfam00005,ABC_tran, ABC transporter.; Specificity unclear; putative ABC transporter ATPase complement(2294598..2295305) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174557 YP_001222775.1 CDS CMM_2033 NC_009480.1 2295302 2296327 R conserved hypothetical protein, weak similarity to multidrug export proteins (NP_903507.1| probable multidrug efflux membrane protein [Chromobacterium violaceum ATCC 12472]; NP_251079.1| conserved hypothetical protein [Pseudomonas aeruginosa PA01]).; Function unclear; hypothetical protein complement(2295302..2296327) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175903 YP_001222776.1 CDS CMM_2034 NC_009480.1 2296540 2298216 R putative hydrolase, metallo-beta-lactamase superfamily (NP_823691.1| putative hydrolase of the metallo-beta-lactamase superfamily [Streptomyces avermitilis MA-4680]; NP_629870.1| conserved hypothetical protein SC9A10.09 [Streptomyces coelicolor A3(2)]). pfam00753, Lactamase_B, Metallo-beta-lactamase superfamily.; Function unclear; metallo-beta-lactamase family hydrolase complement(2296540..2298216) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175138 YP_001222777.1 CDS dapA NC_009480.1 2298275 2299249 R putative dihydrodipicolinate synthase (O86841|DAP1_STRCO Dihydrodipicolinate synthase 1 (DHDPS 1); ZP_00225471.1| COG0329: Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Kineococcus radiotolerans SRS30216]). pfam00701, DHDPS,Dihydrodipicolinate synthetase family. InterPro: Dihydrodipicolinate synthetase.; High confidence in function and specificity; dihydrodipicolinate synthase complement(2298275..2299249) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175185 YP_001222778.1 CDS CMM_2036 NC_009480.1 2299389 2300642 D hypothetical protein 2299389..2300642 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175089 YP_001222779.1 CDS thyX NC_009480.1 2300672 2301463 R flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase complement(2300672..2301463) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175325 YP_001222780.1 CDS CMM_2038 NC_009480.1 2301571 2302491 D putative nucleoside-diphosphate sugar epimerase (ZP_00050154.1| COG1090: Predicted nucleoside-diphosphate sugar epimerase [Magnetospirillum magnetotacticum]; NP_827190.1| putative NAD dependent epimerase/dehydratase family [Streptomyces avermitilis MA-4680]).; Function unclear; putative nucleoside-diphosphate sugar epimerase 2301571..2302491 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174987 YP_001222781.1 CDS CMM_2039 NC_009480.1 2302512 2302961 R conserved membrane protein (P46830|YDAB_MYCBO Hypothetical 19.3 kDa protein in dapB 3'region (ORF Z); NP_629865.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; Conserved hypothetical protein; hypothetical protein complement(2302512..2302961) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175455 YP_001222782.1 CDS dapB NC_009480.1 2302961 2303794 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(2302961..2303794) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175449 YP_001222783.1 CDS gmpB NC_009480.1 2303854 2304456 R putative phosphoglycerate mutase (NP_631275.1| putative phosphoglycerate mutase [Streptomyces coelicolor A3(2)]; Q8ZJU8|GPMB_SALTY Probable phosphoglycerate mutase gpmB (Phosphoglyceromutase) (PGAM)). pfam00300,PGAM, Phosphoglycerate mutase family.; Specificity unclear; hypothetical protein complement(2303854..2304456) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175123 YP_001222784.1 CDS pepR NC_009480.1 2304465 2305820 R putative metallopeptidase, family M16 (ZP_00227821.1| COG0612: Predicted Zn-dependent peptidases [Kineococcus radiotolerans SRS30216]; O86835|YLD8_STRCO Hypothetical zinc protease SCO5738). pfam00675,Peptidase_M16, Insulinase (Peptidase family M16). pfam05193, Peptidase_M16_C, Peptidase M16 inactive domain. InterPro: Insulinase family (Peptidase family M16).; Specificity unclear; M16 family metallopeptidase complement(2304465..2305820) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175052 YP_001222785.1 CDS CMM_2043 NC_009480.1 2305884 2306792 R hypothetical protein (ZP_00412660.1| hypothetical protein ArthDRAFT_2763 [Arthrobacter sp. FB24]; ZP_00658097.1| hypothetical protein NocaDRAFT_2263 [Nocardioides sp. JS614]).; hypothetical protein complement(2305884..2306792) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175042 YP_001222786.1 CDS CMM_2044 NC_009480.1 2307500 2308606 R putative oxidoreductase (NP_733626.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00106480.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Nostoc punctiforme]). pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative oxidoreductase complement(2307500..2308606) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175557 YP_001222787.1 CDS CMM_2045 NC_009480.1 2309060 2309590 D conserved hypothetical protein, putative phospholipid-binding protein (NP_628200.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_960819.1| hypothetical protein MAP1885c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam01161, PBP,Phosphatidylethanolamine-binding protein.; Function unclear; hypothetical protein 2309060..2309590 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175472 YP_001222788.1 CDS CMM_2046 NC_009480.1 2309613 2309999 D hypothetical protein 2309613..2309999 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175536 YP_001222789.1 CDS pnpA NC_009480.1 2310069 2312342 R putative polyribonucleotide nucleotidyltransferase (Polynucleotide phosphorylase) (ZP_00227822.1| COG1185: Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) [Kineococcus radiotolerans SRS30216]; NP_787549.1| polyribonucleotide nucleotidyltransferase [Tropheryma whipplei str. Twist]). pfam01138, RNase_PH, 3' exoribonuclease family, domain 1. This family includes 3'-5' exoribonucleases (twice). pfam03725, RNase_PH_C, 3' exoribonuclease family, domain 2 (twice). pfam03726,PNPase, Polyribonucleotide nucleotidyltransferase, RNA binding domain. pfam00575, S1, S1 RNA binding domain. The S1 domain occurs in a wide range of RNA associated proteins.; High confidence in function and specificity; polynucleotide phosphorylase/polyadenylase complement(2310069..2312342) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175509 YP_001222790.1 CDS rpsO NC_009480.1 2312820 2313089 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(2312820..2313089) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173271 YP_001222791.1 CDS CMM_2049 NC_009480.1 2313325 2314626 D putative MFS permease (ZP_00190511.2| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_599375.1| permease of the major facilitator superfamily [Corynebacterium glutamicum ATCC 13032]).; Specificity unclear; putative MFS permease 2313325..2314626 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175217 YP_001222792.1 CDS CMM_2050 NC_009480.1 2314653 2315384 D conserved hypothetical protein (ZP_00226454.1| hypothetical protein Krad06003337 [Kineococcus radiotolerans SRS30216]; NP_739263.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; hypothetical protein 2314653..2315384 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175585 YP_001222793.1 CDS CMM_2051 NC_009480.1 2315628 2317202 R putative dicarboxylate transporter, DASS family (NP_348217.1| 2-oxoglutarate/malate translocator [Clostridium acetobutylicum ATCC 824]; ZP_00322706.1| COG0471: Di- and tricarboxylate transporters [Pediococcus pentosaceus ATCC 25745])., pfam00939, Na_sulph_symp,Sodium:sulfate symporter transmembrane region.; Specificity unclear; 2-oxoglutarate/malate translocator complement(2315628..2317202) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175562 YP_001222794.1 CDS CMM_2052 NC_009480.1 2317307 2319583 R putative ATP-dependent DNA helicase (ZP_00226623.1| COG3973: Superfamily I DNA and RNA helicases [Kineococcus radiotolerans SRS30216]; ZP_00120699.1| COG3973: Superfamily I DNA and RNA helicases [Bifidobacterium longum DJO10A]). InterPro: UvrD/REP helicase pfam00580,UvrD-helicase, UvrD/REP helicase.; Function unclear; putative ATP-dependent DNA helicase complement(2317307..2319583) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175627 YP_001222795.1 CDS CMM_2053 NC_009480.1 2319688 2320176 R putative membrane protein (ZP_00322542.1| COG4767: Glycopeptide antibiotics resistance protein [Pediococcus pentosaceus ATCC 25745]; NP_940629.1| Conserved integral membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam04892, VanZ, VanZ like family.; Hypothetical protein; hypothetical protein complement(2319688..2320176) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175577 YP_001222796.1 CDS metE2 NC_009480.1 2320419 2321678 D putative methionine synthase II (cobalamin-independent), 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (ZP_00226646.1| COG0620: Methionine synthase II (cobalamin-independent); NP_601330.1| methionine synthase II [Corynebacterium glutamicum ATCC 13032]). , pfam01717, Methionine_synt,Methionine synthase, vitamin-B12 independent.; High confidence in function and specificity; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 2320419..2321678 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175133 YP_001222797.1 CDS aptA NC_009480.1 2321683 2322210 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(2321683..2322210) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173678 YP_001222798.1 CDS CMM_2056 NC_009480.1 2322317 2323048 D conserved membrane protein (NP_824217.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]; ZP_00292627.1| hypothetical protein Tfus02001905 [Thermobifida fusca]).; Conserved hypothetical protein; hypothetical protein 2322317..2323048 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175053 YP_001222799.1 CDS CMM_2057 NC_009480.1 2323130 2323963 R putative 2,5-diketo-D-gluconic acid reductase (NP_631409.1| oxidoreductase. [Streptomyces coelicolor A3(2)]; A45961 2,5-diketo-D-gluconate reductase (EC 1.1.1.-) - Corynebacterium sp. (strain SHS752001)). pfam00248, Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.; Specificity unclear; putative 2,5-diketo-D-gluconic acid reductase complement(2323130..2323963) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175611 YP_001222800.1 CDS lspA NC_009480.1 2323986 2324600 R putative lipoprotein signal peptidase (Signal peptidase II) (CAF20476.1| LIPOPROTEIN SIGNAL PEPTIDASE [Corynebacterium glutamicum ATCC 13032]; H70760 probable lipoprotein signal peptidase - Mycobacterium tuberculosis (strain H37RV)). This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity). lspA: lipoprotein signal peptidase pfam01252,Peptidase_A8, Signal peptidase (SPase) II.; Specificity unclear; putative lipoprotein signal peptidase complement(2323986..2324600) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175698 YP_001222801.1 CDS CMM_2059 NC_009480.1 2324610 2325137 R hypothetical protein (weak similaritiy to NP_625313.1| putative lipoprotein [Streptomyces coelicolor A3(2)]; NP_822599.1| hypothetical protein [Streptomyces avermitilis MA-4680]).; hypothetical protein complement(2324610..2325137) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175300 YP_001222802.1 CDS CMM_2060 NC_009480.1 2325185 2325751 R putative cysteine peptidase, family C56 (NP_866072.1| proteinase I [Pirellula sp. 1]; ZP_00056842.1| COG0693: Putative intracellular protease/amidase [Thermobifida fusca]). pfam01965, DJ-1_PfpI, DJ-1/PfpI family. The family includes the protease PfpI. This domain is also found in transcriptional regulators.; Specificity unclear; cysteine peptidase family protein C56 complement(2325185..2325751) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175620 YP_001222803.1 CDS CMM_2061 NC_009480.1 2325834 2326712 R conserved hypothetical protein (ZP_00212210.1| COG3386: Gluconolactonase [Burkholderia cepacia R18194]; NP_925815.1| hypothetical protein gll2869 [Gloeobacter violaceus]) in eukaryotes a Ca-binding regulatory protein (pfam03758, SMP-30, Senescence marker protein-30 (SMP-30). SMP-30, also known as regucalcin, seems to play a critical role in the highly differentiated functions of the liver and kidney and to exert a major impact on Ca2+ homeostasis).; Family membership; hypothetical protein complement(2325834..2326712) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175745 YP_001222804.1 CDS dpsB NC_009480.1 2326956 2327516 D putative DNA-binding ferritin-like protein (ZP_00226002.1| COG0783: DNA-binding ferritin-like protein (oxidative damage protectant) [Kineococcus radiotolerans SRS30216]; NP_822781.1| hypothetical protein SAV1605 [Streptomyces avermitilis MA-4680]). pfam00210, Ferritin,Ferritin-like domain. This family contains ferritins and other ferritin-like proteins such as members of the DPS family and bacterioferritins.; Function unclear; putative DNA-binding ferritin-like protein 2326956..2327516 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175720 YP_001222805.1 CDS CMM_2063 NC_009480.1 2327638 2328435 D putative short chain dehydrogenase/oxidoreductase (NP_642446.1| 3-ketoacyl-acyl carrier protein reductase [Xanthomonas axonopodis pv. citri str. 306]; ZP_00052290.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Magnetospirillum magnetotacticum]). InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; short chain dehydrogenase/oxidoreductase 2327638..2328435 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173770 YP_001222806.1 CDS CMM_2064 NC_009480.1 2328435 2328644 D hypothetical protein (NP_631705.1| hypothetical protein [Streptomyces coelicolor A3(2)]; NP_883707.1| conserved hypothetical protein Bordetella parapertussis 12822]).; hypothetical protein 2328435..2328644 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175754 YP_001222807.1 CDS CMM_2065 NC_009480.1 2328724 2329971 D putative two-component system sensor kinase (NP_825857.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; ZP_00228428.1| COG4585: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]). InterPro: Histidine kinase- DNA gyrase B- phytochrome-like ATPase pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 2328724..2329971 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175733 YP_001222808.1 CDS CMM_2066 NC_009480.1 2329968 2330630 D putative two-component system response regulator (NP_625929.1| putative two-component response regulator [Streptomyces coelicolor A3(2)]; ZP_00229057.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]). InterPro: Response regulator receiver domain pfam00072, Response_reg, Response regulator receiver domain. pfam00196, GerE, Bacterial regulatory proteins,luxR family.; Specificity unclear; putative two-component system response regulator 2329968..2330630 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175942 YP_001222809.1 CDS dacB NC_009480.1 2330668 2332107 R putative D-alanyl-D-alanine carboxypeptidase (penicillin binding protein precursor) (NP_338276.1| D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family [Mycobacterium tuberculosis CDC1551]; ZP_00058807.1| COG2027: D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Thermobifida fusca]). InterPro: D-Ala-D-Ala carboxypeptidase 3 (S13) family pfam02113, Peptidase_S13,D-Ala-D-Ala carboxypeptidase 3 (S13) family. PBP4: D-alanyl-D-alanine carboxypeptid; High confidence in function and specificity; D-alanyl-D-alanine carboxypeptidase complement(2330668..2332107) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175871 YP_001222810.1 CDS CMM_2068 NC_009480.1 2332162 2332794 R DNA-invertase (Site-specific recombinase)(ZP_00016441.1| COG1961: Site-specific recombinases, DNA invertase Pin homologs [Rhodospirillum rubrum]; NP_061675.1| recombinase [Xylella fastidiosa]). InterPro: Site-specific recombinase pfam00239, Resolvase,Resolvase, N terminal domain. The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface.; Specificity unclear; putative DNA-invertase/recombinase complement(2332162..2332794) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175007 YP_001222811.1 CDS CMM_2069 NC_009480.1 2332896 2333174 R hypothetical protein (ZP_00227354.1| hypothetical protein Krad06001085 [Kineococcus radiotolerans SRS30216]; ZP_00050340.2| COG0532: Translation initiation factor 2 (IF-2; GTPase)[Magnetospirillum magnetotacticum]).; hypothetical protein complement(2332896..2333174) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175191 YP_001222812.1 CDS CMM_2070 NC_009480.1 2333276 2334481 R conserved membrane protein (ZP_00294063.1| COG2339: Predicted membrane protein [Thermobifida fusca]; NP_628289.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]).; Function unclear; hypothetical protein complement(2333276..2334481) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174354 YP_001222813.1 CDS CMM_2071 NC_009480.1 2334589 2336016 R putative FAD/FMN-containing dehydrogenase/oxidoreductase (ZP_00227456.1| COG0277: FAD/FMN-containing dehydrogenases [Kineococcus radiotolerans SRS30216]; NP_826328.1| putative glycolate oxidase [Streptomyces avermitilis MA-4680]). InterPro: FAD linked oxidase C-terminal. pfam01565, FAD_binding_4, FAD binding domain. pfam02913, FAD-oxidase_C, FAD linked oxidases, C-terminal domain. glcD: glycolate oxidase subunit GlcD; Specificity unclear; putative FAD/FMN-containing dehydrogenase complement(2334589..2336016) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175284 YP_001222814.1 CDS CMM_2072 NC_009480.1 2336075 2337010 D putative DNA glycosylase (ZP_00139319.1| COG0122: 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [Pseudomonas aeruginosa UCBPP-PA14]; ZP_00277968.1| COG0122: 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [Burkholderia fungorum LB400]). pfam06029,AlkA_N, AlkA N-terminal domain. pfam00730, HhH-GPD, HhH-GPD superfamily base excision DNA repair protein. This family contains a diverse range of structurally related DNA repair proteins.; Function unclear; putative DNA glycosylase 2336075..2337010 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175177 YP_001222815.1 CDS CMM_2073 NC_009480.1 2337014 2338063 R Region created by contig update; hypothetical protein complement(2337014..2338063) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175054 YP_001222816.1 CDS CMM_2074 NC_009480.1 2338121 2340619 D catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; ATP-dependent DNA ligase 2338121..2340619 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175015 YP_001222817.1 CDS CMM_2075 NC_009480.1 2340710 2341588 D putative hydrolase (NP_437231.1| putative bifunctional enzyme 2-hydroxyhepta-2,4-diene-1,7-dioatesomerase 5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioatedecarboxylase protein [Sinorhizobium meliloti 1021]; NP_697278.1| fumarylacetoacetate hydrolase family protein [Brucella suis 1330]). InterPro: Fumarylacetoacetate (FAA) hydrolase family pfam01557,FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family.; Function unclear; putative hydrolase 2340710..2341588 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174758 YP_001222818.1 CDS CMM_2075A NC_009480.1 2341631 2341768 D hypothetical protein 2341631..2341768 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174782 YP_001222819.1 CDS CMM_2076 NC_009480.1 2341812 2342720 D hypothetical protein pfam01442, Apolipoprotein,Apolipoprotein A1/A4/E family.; hypothetical protein 2341812..2342720 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174831 YP_001222820.1 CDS aspA NC_009480.1 2342798 2344315 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(2342798..2344315) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174732 YP_001222821.1 CDS CMM_2078 NC_009480.1 2344422 2345273 D conserved hypothetical protein (ZP_00326425.1| COG4328: Uncharacterized protein conserved in bacteria [Trichodesmium erythraeum IMS101]; NP_485314.1| hypothetical protein [Nostoc sp. PCC 7120]).; hypothetical protein 2344422..2345273 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174637 YP_001222822.1 CDS CMM_2079 NC_009480.1 2345295 2346041 R putative glycosyl transferase (NP_968447.1| putative glycosyl transferase [Bdellovibrio bacteriovorus HD100]; ZP_00188968.2| COG0463: Glycosyltransferases involved in cell wall biogenesis [Kineococcus radiotolerans SRS30216]; NP_738216.1| putative prenol monophospho-mannose synthase [Corynebacterium efficiens YS-314]). InterPro: Glycosyl transferase family 2 pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; glycosyl transferase family protein complement(2345295..2346041) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175342 YP_001222823.1 CDS CMM_2080 NC_009480.1 2346231 2346752 D putative membrane protein (ZP_00121383.2| COG2246: Predicted membrane protein [Bifidobacterium longum DJO10A]; NP_627281.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides.; Hypothetical protein; hypothetical protein 2346231..2346752 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173407 YP_001222824.1 CDS CMM_2081 NC_009480.1 2346772 2348049 R putative manganese transport protein, NRAMP family (NP_629145.1| putative metal ion transport protein [Streptomyces coelicolor A3(2)]; ZP_00188446.1| COG1914: Mn2+ and Fe2+ transporters of the NRAMP family [Rubrobacter xylanophilus DSM 9941]). pfam01566, Nramp,Natural resistance-associated macrophage protein. This family of membrane proteins are divalent cation transporters.; Specificity unclear; Mn2+/Fe2+ transporter complement(2346772..2348049) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174848 YP_001222825.1 CDS CMM_2082 NC_009480.1 2348147 2349622 R putative xanthine/uracil permease, MFS superfamily (CAF19530.1| Xanthine/uracil permeases family [Corynebacterium glutamicum ATCC 13032]; NP_827562.1| putative hypoxanthine/guanine permease [Streptomyces avermitilis MA-4680]). , InterPro: Xanthine/uracil permeases family , pfam00860, Xan_ur_permease, Permease family. This family includes permeases for diverse substrates such as xanthine, uracil and vitamin C. However many members of this family are functionally uncharacterised and may transport other substrates.; Specificity unclear; MFS family xanthine/uracil permease complement(2348147..2349622) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175926 YP_001222826.1 CDS CMM_2083 NC_009480.1 2349748 2349999 R Hypothetical protein; hypothetical protein complement(2349748..2349999) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174807 YP_001222827.1 CDS pitB NC_009480.1 2349996 2351177 R putative low-affinity inorganic phosphate permease (NP_599707.1| phosphate/sulphate permease [Corynebacterium glutamicum ATCC 13032]; NP_827595.1| putative transporter [Streptomyces avermitilis MA-4680]). InterPro: Phosphate transporter family pfam01384, PHO4, Phosphate transporter family.; Specificity unclear; low-affinity inorganic phosphate permease complement(2349996..2351177) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173956 YP_001222828.1 CDS lipT NC_009480.1 2351296 2352957 R putative carboxylesterase type B (NP_949230.1| putative carboxylesterase [Rhodopseudomonas palustris CGA009]; CAA17259.1| Probable carboxylesterase LipT [Mycobacterium tuberculosis H37Rv]). InterPro: Carboxylesterases type-B pfam00135, COesterase,Carboxylesterase.; High confidence in function and specificity; carboxylesterase complement(2351296..2352957) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173533 YP_001222829.1 CDS CMM_2086 NC_009480.1 2352954 2354537 R conserved hypothetical protein (NP_336756.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]; NP_940012.1| Conserved hypothetical protein [Corynebacterium diphtheriae]). pfam01928, CYTH, CYTH domain. pfam05235, CHAD, CHAD domain. The CHAD domain is an alpha-helical domain functionally associated with the pfam01928 domains. It has conserved histidines that may chelate metals.; hypothetical protein complement(2352954..2354537) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174065 YP_001222830.1 CDS CMM_2087 NC_009480.1 2354629 2355816 D conserved hypothetical protein (|ZP_00059173.1| COG1295: Predicted membrane protein [Thermobifida fusca]; NP_737633.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam03631,Ribonuclease_BN, Ribonuclease BN-like family. This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity.; Family membership; hypothetical protein 2354629..2355816 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174710 YP_001222831.1 CDS CMM_2088 NC_009480.1 2355761 2356780 R putative NADP-dependent oxidoreductase (ZP_00226498.1| COG2130: Putative NADP-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_826953.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]). InterPro: Zinc-containing alcohol dehydrogenase superfamily pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Function unclear; putative oxidoreductase complement(2355761..2356780) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174659 YP_001222832.1 CDS CMM_2089 NC_009480.1 2356917 2357858 R putative NAD-dependent epimerase/dehydratase (ZP_00228901.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; AAO42400.1| putative pinoresinol- lariciresinol reductase [Arabidopsis thaliana]). InterPro: Isoflavone reductase; Family membership; putative NAD-dependent epimerase/dehydratase complement(2356917..2357858) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174427 YP_001222833.1 CDS CMM_2090 NC_009480.1 2359330 2360022 R putative short chain dehydrogenase/oxidoreductase (NP_294134.1| oxidoreductase, short-chain dehydrogenase/reductase family [Deinococcus radiodurans]; NP_738947.1| putative reductase [Corynebacterium efficiens YS-314]). InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase complement(2359330..2360022) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174462 YP_001222834.1 CDS CMM_2091 NC_009480.1 2360157 2360507 D hypothetical protein 2360157..2360507 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174399 YP_001222835.1 CDS hsp20 NC_009480.1 2360643 2361101 D chaperone, heat shock protein, HSP20 family (CAD59401.1| putative heat shock protein 20_1 [Propionibacterium freudenreichii subsp. shermanii]; NP_821867.1| putative heat shock protein [Streptomyces avermitilis MA-4680]). InterPro: Heat shock hsp20 (alpha crystallin) proteins family pfam00011, HSP20, Hsp20/alpha crystallin family.; High confidence in function and specificity; HSP20 family protein 2360643..2361101 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174263 YP_001222836.1 CDS alcBC NC_009480.1 2361212 2363728 R putative siderophore biosynthesis protein (NP_931792.1| hypothetical protein [Photorhabdus luminescens subsp. laumondii TTO1]; ZP_00162775.2| COG4264: Siderophore synthetase component [Anabaena variabilis ATCC 29413]). two-domain protein: N-terminal: putative acetyl transferase (NC_003155.2, AlcB,Streptomyces avermitilis MA-4680, putative aceytltranferase). C-terminal: NC_003155.2, Streptomyces avermitilis MA-4680, putative siderophore biosynthetic enzyme, AlcC. pfam04183, IucA_IucC, IucA / IucC family. IucA and IucC catalyse discrete steps in biosynthesis of the siderophore aerobactin from N epsilon-acetyl-N epsilon-hydroxylysine and citrate.; Function unclear; putative siderophore biosynthesis protein complement(2361212..2363728) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175635 YP_001222837.1 CDS alcA NC_009480.1 2363725 2365095 R putative monooxygenase/hydroxylase (NP_826448.1| putative monooxigenase, AlcA, Streptomyces avermitilis MA-4680; NP_405116.1| putative siderophore biosynthetic enzyme, Yersinia pestis; ZP_00119405.1| COG3486: Lysine/ornithine N-monooxygenase, Cytophaga hutchinsonii); Specificity unclear; putative siderophore biosynthesis enzyme/monooxygenase complement(2363725..2365095) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173106 YP_001222838.1 CDS CMM_2095 NC_009480.1 2365092 2366702 R putative L-2,4-diaminobutyrate decarboxylase (NP_826449.1| putative L-2,4-diaminobutyrate decarboxylase [Streptomyces avermitilis MA-4680]; NP_405115.1| putative decarboxylase [Yersinia pestis]). InterPro: Pyridoxal-dependent decarboxylase family pfam00282, Pyridoxal_deC,Pyridoxal-dependent decarboxylase conserved domain.; Specificity unclear; L-amino acid decarboxylase complement(2365092..2366702) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173530 YP_001222839.1 CDS CMM_2095A NC_009480.1 2366913 2367224 D hypothetical protein 2366913..2367224 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174298 YP_001222840.1 CDS CMM_2095B NC_009480.1 2367226 2367378 D hypothetical protein 2367226..2367378 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174338 YP_001222841.1 CDS CMM_2096 NC_009480.1 2367480 2367764 D hypothetical protein 2367480..2367764 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174195 YP_001222842.1 CDS CMM_2097 NC_009480.1 2367761 2368054 D hypothetical protein 2367761..2368054 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174114 YP_001222843.1 CDS CMM_2098 NC_009480.1 2368102 2368998 D putative short chain dehydrogenase/oxidoreductase (NP_737722.1| putative oxidoreductase [Corynebacterium efficiens YS-314]; NP_641514.1| oxidoreductase [Xanthomonas axonopodis pv. citri str. 306])). pfam00106,adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase 2368102..2368998 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173958 YP_001222844.1 CDS CMM_2099 NC_009480.1 2369127 2369858 D hypothetical protein (ZP_00226806.1| hypothetical protein Krad06002561 [Kineococcus radiotolerans SRS30216]; NP_962000.1| hypothetical protein MAP3066c [Mycobacterium avium subsp. paratuberculosis str. k10]).; hypothetical protein 2369127..2369858 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173966 YP_001222845.1 CDS CMM_2100 NC_009480.1 2370010 2370741 R putative membrane protein; hypothetical protein complement(2370010..2370741) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173996 YP_001222846.1 CDS CMM_2101 NC_009480.1 2371085 2371822 R hypothetical protein complement(2371085..2371822) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173847 YP_001222847.1 CDS CMM_2102 NC_009480.1 2372140 2373021 D putative membrane protein containing a 2Fe-2S domain (ZP_00293646.1| COG4244: Predicted membrane protein [Thermobifida fusca]; ZP_00227494.1| COG2146: Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases [Kineococcus radiotolerans SRS30216]). N:terminal: COG4244, COG4244, Predicted membrane protein C-terminal: InterPro: Rieske iron-sulfur protein 2Fe-2S subunit pfam00355, Rieske, Rieske [2Fe-2S] domain. COG2146, {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Function unclear; 2Fe-2S domain-containing protein 2372140..2373021 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173761 YP_001222848.1 CDS CMM_2103 NC_009480.1 2373103 2374563 R conserved hypothetical protein, putative protease (T35375 probable membrane protein - Streptomyces coelicolor; ZP_00228735.1| COG2268: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). N-terminal: pfam01145, Band_7, SPFH domain / Band 7 family. C-terminal: pfam03149, Flotillin, Flotillin family.; Function unclear; hypothetical protein complement(2373103..2374563) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173824 YP_001222849.1 CDS CMM_2104 NC_009480.1 2374595 2375083 R Function unclear; hypothetical protein complement(2374595..2375083) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173683 YP_001222850.1 CDS CMM_2105 NC_009480.1 2375265 2375525 D hypothetical protein (NP_822693.1| hypothetical protein SAV1518 [Streptomyces avermitilis MA-4680]).; hypothetical protein 2375265..2375525 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173636 YP_001222851.1 CDS CMM_2106 NC_009480.1 2375647 2376999 D putative sugar ABC transporter, binding protein (NP_624969.1| probable solute-binding lipoprotein. [Streptomyces coelicolor A3(2)]; ZP_00121005.2| COG1653: ABC-type sugar transport system, periplasmic component [Bifidobacterium longum DJO10A]). InterPro: Bacterial extracellular solute-binding protein family 1. pfam01547,SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter binding protein 2375647..2376999 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173697 YP_001222852.1 CDS CMM_2107 NC_009480.1 2376996 2378012 D putative sugar ABC transporter, permease component (ZP_00227865.1| COG1175: ABC-type sugar transport systems,permease components [Kineococcus radiotolerans SRS30216]; ZP_00121800.2| COG1175: ABC-type sugar transport systems,permease components [Bifidobacterium longum DJO10A]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 2376996..2378012 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173548 YP_001222853.1 CDS CMM_2108 NC_009480.1 2378009 2378977 D putative sugar ABC transporter, permease component (ZP_00121009.2| COG0395: ABC-type sugar transport system,permease component [Bifidobacterium longum DJO10A]; NP_631458.1| putative binding-protein dependent transport protein. [Streptomyces coelicolor A3(2)]). InterPro: Binding-protein-dependent transport systems inner membrane component. pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 2378009..2378977 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173519 YP_001222854.1 CDS lacZ NC_009480.1 2379114 2382167 D putative beta-galactosidase (Q59140|BGAL_ARTSB Beta-galactosidase (Lactase); NP_823271.1| putative beta-galactosidase [Streptomyces avermitilis MA-4680]). pfam02837, Glyco_hydro_2_N, Glycosyl hydrolases family 2,sugar binding domain. pfam02836, Glyco_hydro_2_C, Glycosyl hydrolases family 2, TIM barrel domain. pfam02929,Bgal_small_N, Beta galactosidase small chain, N terminal domain. pfam02930, Bgal_small_C, Beta galactosidase small chain, C terminal domain.; High confidence in function and specificity; beta-galactosidase 2379114..2382167 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173595 YP_001222855.1 CDS CMM_2110 NC_009480.1 2382278 2383564 D putative sugar alcohol dehydrogenase (Q9ZBU1|XYOA_STRCO Probable xylitol oxidase; ZP_00228154.1| COG0277: FAD/FMN-containing dehydrogenases [Kineococcus radiotolerans SRS30216]). pfam01565,FAD_binding_4, FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are; Specificity unclear; putative sugar alcohol dehydrogenase 2382278..2383564 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173676 YP_001222856.1 CDS CMM_2111 NC_009480.1 2383679 2383948 D putative glutaredoxin (ZP_00227600.1| COG0695: Glutaredoxin and related proteins [Kineococcus radiotolerans SRS30216]; NP_629335.1| putative glutaredoxin-like protein [Streptomyces coelicolor A3(2)]). InterPro: Thioredoxin. pfam00462, Glutaredoxin,Glutaredoxin. redox_disulf_1: redox-active disulfide; Function unclear; putative glutaredoxin 2383679..2383948 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173483 YP_001222857.1 CDS CMM_2112 NC_009480.1 2383952 2385421 D conserved hypothetical protein, putative phosphotransferase (ZP_00228505.1| COG3281: Uncharacterized protein, probably involved in trehalose biosynthesis [Kineococcus radiotolerans SRS30216]; ZP_00293344.1| COG3281: Uncharacterized protein, probably involved in trehalose biosynthesis [Thermobifida fusca]).; Function unclear; putative phosphotransferase 2383952..2385421 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173370 YP_001222858.1 CDS CMM_2113 NC_009480.1 2385893 2386117 D Hypothetical protein; hypothetical protein 2385893..2386117 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173630 YP_001222859.1 CDS ptrB NC_009480.1 2386220 2388385 D putative protease II (Oligopeptidase B)(NP_335233.1| protease II [Mycobacterium tuberculosis CDC1551]; NP_940260.1| Putative prolyl oligopeptidase [Corynebacterium diphtheriae NCTC 13129]). pfam02897,Peptidase_S9_N, Prolyl oligopeptidase, N-terminal beta-propeller domain. pfam00326, Peptidase_S9, Prolyl oligopeptidase family. InterPro: Prolyl oligopeptidase N-terminal beta-propeller domain.; High confidence in function and specificity; putative protease II (oligopeptidase B) 2386220..2388385 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174042 YP_001222860.1 CDS thiM NC_009480.1 2388531 2389358 D hydroxyethylthiazole kinase (NP_713545.1| hydroxyethylthiazole kinase [Leptospira interrogans serovar lai str. 56601]; Q8X7G3|THIM_ECO57 Hydroxyethylthiazole kinase (4-methyl-5-beta-hydroxyethylthiazole kinase) (Thz kinase) (TH kinase)). pfam02110, HK, Hydroxyethylthiazole kinase family.; High confidence in function and specificity; hypothetical protein 2388531..2389358 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173647 YP_001222861.1 CDS thiED NC_009480.1 2389355 2391586 D catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; multifunctional thiamine-phosphate pyrophosphorylase/synthase/phosphomethylpyrimidine kinase 2389355..2391586 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175026 YP_001222862.1 CDS CMM_2117 NC_009480.1 2391766 2392656 D conserved hypothetical protein, putative fusion protein. N-terminal: COG1917, COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain (NP_534846.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]; ZP_00105951.1| COG1917: Uncharacterized conserved protein, contains double-stranded beta-helix domain [Nostoc punctiforme]). C-terminal: similarity to NP_641577.1| hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]; ZP_00205709.1| hypothetical protein Psyr022367 [Pseudomonas syringae pv. syringae B728a]). panD: aspartate 1-decarboxylase; Function unclear; putative fusion protein 2391766..2392656 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175615 YP_001222863.1 CDS CMM_2118 NC_009480.1 2392771 2394168 D putative sugar MFS permease (BAC00372.1| Permeases of the major facilitator superfamily [Corynebacterium glutamicum ATCC 13032]; ZP_00227700.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam00083, Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters.; Specificity unclear; putative sugar MFS permease 2392771..2394168 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173555 YP_001222864.1 CDS CMM_2119 NC_009480.1 2394451 2394660 D Hypothetical protein; hypothetical protein 2394451..2394660 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175894 YP_001222865.1 CDS CMM_2120 NC_009480.1 2394728 2396863 R putative DNA helicase (NP_787246.1| DNA helicase [Tropheryma whipplei str. Twist]). pfam00176, SNF2_N, SNF2 family N-terminal domain. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Function unclear; putative DNA helicase complement(2394728..2396863) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173275 YP_001222866.1 CDS CMM_2121 NC_009480.1 2397158 2398306 D putative glutathion S-transferase (ZP_00190023.2| COG0435: Predicted glutathione S-transferase [Kineococcus radiotolerans SRS30216]; NP_600487.1| predicted glutathione S-transferase [Corynebacterium glutamicum ATCC 13032]).; Family membership; putative glutathione S-transferase 2397158..2398306 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173426 YP_001222867.1 CDS CMM_2122 NC_009480.1 2398306 2399100 D putative esterase (BAA82510.1| esterase HDE [petroleum-degrading bacterium HD-1]; ZP_00312658.1| COG0657: Esterase/lipase [Clostridium thermocellum ATCC 27405]).; Family membership; putative esterase 2398306..2399100 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173249 YP_001222868.1 CDS CMM_2123 NC_009480.1 2399063 2399437 R Hypothetical protein; hypothetical protein complement(2399063..2399437) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172974 YP_001222869.1 CDS CMM_2124 NC_009480.1 2399572 2400084 D conserved hypothetical protein (NP_241345.1| BH0479~unknown conserved protein in others [Bacillus halodurans C-125]; NP_993986.1| TPR-repeat-containing proteins [Yersinia pestis biovar Medievalis str. 91001]). weak similarity to: cd00189, TPR, Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi,plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; Function unclear; hypothetical protein 2399572..2400084 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173354 YP_001222870.1 CDS CMM_2125 NC_009480.1 2400081 2400482 D hypothetical protein 2400081..2400482 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174452 YP_001222871.1 CDS CMM_2126 NC_009480.1 2400540 2401580 D putative Zn-dependant alcohol dehydrogenase (NP_102793.1| alcohol dehydrogenase [Mesorhizobium loti MAFF303099]; NP_532825.1| alcohol dehydrogenase [Agrobacterium tumefaciens str. C58]). pfam00107,ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; putative Zn-dependent alcohol dehydrogenase 2400540..2401580 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173224 YP_001222872.1 CDS CMM_2127 NC_009480.1 2401596 2401913 R conserved hypothetical protein (CAA15545.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_925803.1| hypothetical protein gsl2857 [Gloeobacter violaceus PCC 7421]). pfam03992, ABM,Antibiotic biosynthesis monooxygenase.; Function unclear; hypothetical protein complement(2401596..2401913) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173125 YP_001222873.1 CDS poxB NC_009480.1 2401961 2403715 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(2401961..2403715) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174009 YP_001222874.1 CDS CMM_2129 NC_009480.1 2403823 2404554 D conserved hypothetical protein (NP_626020.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_602236.1| hypothetical protein NCgl2940 [Corynebacterium glutamicum ATCC13032]).; Function unclear; hypothetical protein 2403823..2404554 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173908 YP_001222875.1 CDS CMM_2130 NC_009480.1 2404551 2405513 R putative Zn-dependant oxidoreductase (NP_733654.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; NP_962452.1| hypothetical protein MAP3518c [Mycobacterium avium subsp. paratuberculosis str. k10]). InterPro: Zinc-containing alcohol dehydrogenase superfamily pfam00107,ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; putative Zn-dependent oxidoreductase complement(2404551..2405513) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174884 YP_001222876.1 CDS CMM_2131 NC_009480.1 2405657 2406577 D putative transcriptional regulator, LysR family (ZP_00267509.1| COG0583: Transcriptional regulator [Rhodospirillum rubrum]; NP_102796.1| probable transcriptional regulator [Mesorhizobium loti MAFF303099]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466,LysR_substrate, LysR substrate binding domain.; Specificity unclear; LysR family transcriptional regulator 2405657..2406577 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174521 YP_001222877.1 CDS CMM_2132 NC_009480.1 2408857 2409756 D putative transcriptional regulator, TetR family (P09164|TER4_ECOLI Tetracycline repressor protein class D; NP_792454.1| transcriptional regulator, TetR family [Pseudomonas syringae pv. tomato str. DC3000]).; Specificity unclear; TetR family transcriptional regulator 2408857..2409756 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173459 YP_001222878.1 CDS CMM_2133 NC_009480.1 2409753 2410391 R putative lipase/esterase (ZP_00110422.1| COG2755: Lysophospholipase L1 and related esterases [Nostoc punctiforme]; NP_641188.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]). pfam00657,Lipase_GDSL, GDSL-like Lipase/Acylhydrolase.; putative lipase/esterase complement(2409753..2410391) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173024 YP_001222879.1 CDS CMM_2134 NC_009480.1 2410435 2410884 R putative membrane protein; hypothetical protein complement(2410435..2410884) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173156 YP_001222880.1 CDS CMM_2135 NC_009480.1 2410881 2412407 R putative nucleoside-diphosphate-sugar epimerase (NP_822386.1| hypothetical protein [Streptomyces avermitilis MA-4680]; ZP_00227908.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein complement(2410881..2412407) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175490 YP_001222881.1 CDS CMM_2136 NC_009480.1 2412481 2413242 R hypothetical protein (ZP_00198157.1| COG3832: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]).; hypothetical protein complement(2412481..2413242) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175625 YP_001222882.1 CDS CMM_2137 NC_009480.1 2413422 2414360 D putative sugarkinase (Glucose kinase) (CAB07107.1| POSSIBLE SUGAR KINASE [Mycobacterium tuberculosis H37Rv]; NP_822651.1| putative sugar kinase [Streptomyces avermitilis MA-4680]). pfam00480, ROK, ROK family.; Specificity unclear; putative sugarkinase 2413422..2414360 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173482 YP_001222883.1 CDS CMM_2138 NC_009480.1 2414413 2416014 R conserved hypothetical protein (NP_630250.1| hypothetical protein SC1A9.09 [Streptomyces coelicolor A3(2)]; ZP_00198190.1| COG1387: Histidinol phosphatase and related hydrolases of the PHP family [Kineococcus radiotolerans SRS30216]). pfam02231, PHP_N, PHP domain N-terminal region. The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain. weak similarity to: COG1387, HIS2, Histidinol phosphatase and related hydrolases of the PHP family.; hypothetical protein complement(2414413..2416014) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174885 YP_001222884.1 CDS cynX NC_009480.1 2416143 2417408 R putative cyanate MFS permease (ZP_00225824.1| COG2807: Cyanate permease [Kineococcus radiotolerans SRS30216]; NP_642656.1| MFS transporter [Xanthomonas axonopodis pv. citri str. 306]). TIGRFAM (TIGR00896): Cyanate transport system protein CynX; Specificity unclear; MFS family permease complement(2416143..2417408) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174067 YP_001222885.1 CDS CMM_2140 NC_009480.1 2417443 2418129 D conserved hypothetical protein (ZP_00199464.2| hypothetical protein Krad06000208 [Kineococcus radiotolerans SRS30216]; NP_216552.1| hypothetical protein Rv2036 [Mycobacterium tuberculosis H37Rv]).; hypothetical protein 2417443..2418129 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174640 YP_001222886.1 CDS ribF NC_009480.1 2418126 2419058 R multifunctional Riboflavin biosynthesis protein ribF [Includes: Riboflavin kinase (EC 2.7.1.26) (Flavokinase); FMN adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase) (FAD synthetase)] (NP_823722.1| putative riboflavin kinase [Streptomyces avermitilis MA-4680]; NP_738481.1| riboflavin kinase/FMN adenylyltransferase [Corynebacterium efficiens YS-314]). pfam06574, Flavokinase, Riboflavin kinase (Flavokinase). pfam01687, FAD_Synth, Riboflavin kinase / FAD synthetase. InterPro: Riboflavin kinase / FAD synthetase ribF: riboflavin biosynthesis protein R.; High confidence in function and specificity; bifunctional riboflavin kinase/FMN adenylyltransferase complement(2418126..2419058) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173159 YP_001222887.1 CDS CMM_2142 NC_009480.1 2419061 2419522 R putative membrane protein (NP_827963.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]; ZP_00227300.1| hypothetical protein Krad06001357 [Kineococcus radiotolerans SRS30216]).; hypothetical protein complement(2419061..2419522) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175877 YP_001222888.1 CDS CMM_2143 NC_009480.1 2419560 2419928 R putative membrane protein (NP_789537.1| putative membrane protein [Tropheryma whipplei TW08/27]; NP_625839.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]).; Hypothetical protein; hypothetical protein complement(2419560..2419928) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173424 YP_001222889.1 CDS truB NC_009480.1 2419925 2420884 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(2419925..2420884) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173532 YP_001222890.1 CDS apbA NC_009480.1 2420971 2421966 D Putative 2-dehydropantoate 2-reductase (NP_624781.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; NP_949896.1| putative 2-dehydropantoate 2-reductase [Rhodopseudomonas palustris CGA009]). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). pfam02558,ApbA, Ketopantoate reductase PanE/ApbA. InterPro: Ketopantoate reductase ApbA/PanE apbA_panE: 2-dehydropantoate 2-reductase; High confidence in function and specificity; 2-dehydropantoate 2-reductase 2420971..2421966 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174920 YP_001222891.1 CDS CMM_2146 NC_009480.1 2422016 2422582 R hypothetical protein complement(2422016..2422582) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175018 YP_001222892.1 CDS mutY NC_009480.1 2422621 2423499 D A/G-specific adenine glycosylase (NP_825884.1| putative adenine glycosylase [Streptomyces avermitilis MA-4680]; ZP_00293144.1| COG1194: A/G-specific DNA glycosylase [Thermobifida fusca]). ADENINE GLYCOSYLASE ACTIVE ON G-A MISPAIRS. MUTY ALSO CORRECTS ERROR-PRONE DNA SYNTHESIS PAST GO LESIONS WHICH ARE DUE TO THE OXIDATIVELY DAMAGED FORM OF GUANINE: 78-DIHYDRO-8- OXOGUANINE.; High confidence in function and specificity; A/G-specific adenine glycosylase 2422621..2423499 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172937 YP_001222893.1 CDS rbfA NC_009480.1 2423544 2424044 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(2423544..2424044) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174074 YP_001222894.1 CDS infB NC_009480.1 2424224 2427058 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(2424224..2427058) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174013 YP_001222895.1 CDS CMM_2150 NC_009480.1 2427155 2427448 R Region created by contig update; putative nucleic-acid-binding protein complement(2427155..2427448) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175947 YP_001222896.1 CDS nusA NC_009480.1 2427499 2428506 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(2427499..2428506) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174208 YP_001222897.1 CDS proS NC_009480.1 2428593 2430365 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(2428593..2430365) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174586 YP_001222898.1 CDS CMM_2153 NC_009480.1 2430397 2431398 R putative NAD(P)H dependant steroid dehydrogenase/isomerase (AAL01055.1| putative steroid dehydrogenase [Photobacterium profundum]; NP_717355.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Shewanella oneidensis MR-1]). pfam01073, 3Beta_HSD, 3-beta hydroxysteroid dehydrogenase/isomerase family.; Specificity unclear; putative NAD(P)H steroid dehydrogenase/isomerase complement(2430397..2431398) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175736 YP_001222899.1 CDS CMM_2154 NC_009480.1 2431395 2434067 R putative acyl-CoA synthetase (ZP_00353402.1| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Kineococcus radiotolerans SRS30216]; two-domain protein: N-terminal (AA 1-330):COG0596, MhpC,Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); pfam00561, Abhydrolase_1,alpha/beta hydrolase fold (NP_717353.1| hydrolase,alpha/beta hydrolase fold family [Shewanella oneidensis MR-1]). C-terminal (330- ):COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; pfam00501,AMP-binding, AMP-binding enzyme (ZP_00039494.1| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Xylella fastidiosa Dixon]). InterPro: AMP-dependent synthetase and ligase.; Function unclear; putative acyl-CoA synthetase complement(2431395..2434067) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175223 YP_001222900.1 CDS CMM_2155 NC_009480.1 2434075 2435106 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase complement(2434075..2435106) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173048 YP_001222901.1 CDS ispG NC_009480.1 2435214 2436359 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2435214..2436359) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173097 YP_001222902.1 CDS CMM_2157 NC_009480.1 2436450 2437868 R putative membrane-associated zinc metalloprotease,family M50 (YP_062170.1| zinc metalloprotease [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00059010.1| COG0750: Predicted membrane-associated Zn-dependent proteases 1 [Thermobifida fusca]; NP_823738.1| hypothetical protein [Streptomyces avermitilis MA-4680]). InterPro: PDZ domain (also known as DHR or GLGF) TIGR00054: membrane-associated zinc met; Specificity unclear; M50 family zinc metalloprotease complement(2436450..2437868) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175767 YP_001222903.1 CDS pknF NC_009480.1 2438004 2439254 D putative serine/threonine-protein kinase (NP_623114.1| Serine/threonine protein kinase [Thermoanaerobacter tengcongensis]; NP_785211.1| serine/threonine protein kinase (putative) [Lactobacillus plantarum WCFS1]). pfam00069, Pkinase, Protein kinase domain. InterPro: Serine/Threonine protein kinase.; Function unclear; putative serine/threonine protein kinase 2438004..2439254 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173501 YP_001222904.1 CDS CMM_2159 NC_009480.1 2439251 2439862 D hypothetical protein 2439251..2439862 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173421 YP_001222905.1 CDS dxrA NC_009480.1 2439980 2441062 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(2439980..2441062) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174690 YP_001222906.1 CDS CMM_2161 NC_009480.1 2441071 2442093 R putative peptidyl-prolyl cis-trans isomerase (YP_062168.1| peptidylprolyl isomerase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056093.1| putative peptidyl-prolyl cis-trans isomerase [Propionibacterium acnes KPA171202]). pfam00254, FKBP_C, FKBP-type peptidyl-prolyl cis-trans isomerase (twice). InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase).; Family membership; putative peptidylprolyl isomerase complement(2441071..2442093) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175876 YP_001222907.1 CDS CMM_2162 NC_009480.1 2442228 2442713 R conserved hypothetical protein (YP_062164.1| Hypothetical protein Lxx12120 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00310296.1| COG1764: Predicted redox protein, regulator of disulfide bond formation [Cytophaga hutchinsonii]). pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.; Function unclear; hypothetical protein complement(2442228..2442713) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173613 YP_001222908.1 CDS gabT NC_009480.1 2442785 2444200 D putative 4-aminobutyrate aminotransferase (Gamma-amino-N-butyrate transaminase) (YP_062163.1| 4-aminobutyrate aminotransferase [Leifsonia xyli subsp. xyli str. CTCB07]; P40829|GABT_MYCLE 4-aminobutyrate aminotransferase ((S)-3-amino-2-methylpropionate transaminase) (Gamma-amino-N-butyrate transaminase)). InterPro: 4-aminobutyrate aminotransferase bacterial.; High confidence in function and specificity; putative 4-aminobutyrate aminotransferase 2442785..2444200 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173550 YP_001222909.1 CDS CMM_2164 NC_009480.1 2444200 2445210 D putative asparaginase II (YP_062162.1| Hypothetical protein Lxx12130 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628361.1| hypothetical protein SCO4185 [Streptomyces coelicolor A3(2)]; ZP_00192634.1| COG4448: L-asparaginase II [Mesorhizobium sp. BNC1]). pfam06089,Asparaginase_II, L-asparaginase II.; Specificity unclear; putative asparaginase II 2444200..2445210 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174583 YP_001222910.1 CDS CMM_2165 NC_009480.1 2445200 2448691 R conserved hypothetical protein with duplicated ATPase domain (CAB77299.1| putative cell division-related protein [Streptomyces coelicolor A3(2)]; NP_737190.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam01580, FtsK_SpoIIIE, FtsK/SpoIIIE family. FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids, termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif. It is found in the FtsK cell division protein from E. coli and the stage III sporulation protein E SpoIIIE, which has roles in regulation of prespore specific gene expression in B. subtilis. A mutation in FtsK causes a temperature sensitive block in cell division and it is involved in peptidoglycan synthesis or modification. The SpoIIIE protein is implicated in intercellular chromosomal DNA transfer.; Family membership; hypothetical protein complement(2445200..2448691) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173285 YP_001222911.1 CDS CMM_2166 NC_009480.1 2448782 2451325 R conserved membrane protein containing transglutaminase domain, putative cysteine protease (YP_062159.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00120584.1| COG1305: Transglutaminase-like enzymes, putative cysteine proteases [Bifidobacterium longum DJO10A]). pfam01027, UPF0005,Uncharacterised protein family UPF0005. pfam01841,Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function.; Function unclear; hypothetical protein complement(2448782..2451325) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173136 YP_001222912.1 CDS CMM_2167 NC_009480.1 2451322 2452782 R conserved hypothetical protein (YP_062158.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696370.1| narrowly conserved hypothetical protein with duf54 [Bifidobacterium longum NCC2705]). pfam01882, DUF58, Protein of unknown function DUF58. This family of prokaryotic proteins have no known function. InterPro: Protein of unknown function DUF58.; Function unclear; hypothetical protein complement(2451322..2452782) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173931 YP_001222913.1 CDS CMM_2168 NC_009480.1 2452779 2453822 R MoxR-like ATPase, putative regulator (YP_062157.1| methanol dehydrogenase regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_622051.1| MoxR-like ATPases [Thermoanaerobacter tengcongensis]). pfam00004, AAA,ATPase family associated with various cellular activities (AAA). AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.; Function unclear; MoxR-like ATPase regulator complement(2452779..2453822) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172921 YP_001222914.1 CDS CMM_2169 NC_009480.1 2453881 2459895 R putative RTX toxin (YP_062156.1| fibronectin-related protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00206687.1| COG5295: Autotransporter adhesin [Bifidobacterium longum DJO10A]; NP_696368.1| large protein with C-terminal fibronectin type III domain [Bifidobacterium longum NCC2705]). pfam00041, fn3,Fibronectin type III domain (twice). InterPro: Fibronectin type III domain.; Function unclear; putative RTX toxin complement(2453881..2459895) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174021 YP_001222915.1 CDS pknG NC_009480.1 2459892 2461463 R putative serine/threonine protein kinase (YP_062155.1| serine/ threonine kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696367.1| probable serine/threonine-protein kinase [Bifidobacterium longum NCC2705]; NP_687353.1| serine/threonine protein kinase [Streptococcus agalactiae 2603V/R]). cd00180, S_TKc,Serine/Threonine protein kinases, catalytic domain. Phosphotransferases of the serine or threonine-specific kinase subfamily. pfam00069, Pkinase, Protein kinase domain.; Function unclear; hypothetical protein complement(2459892..2461463) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175402 YP_001222916.1 CDS gltA NC_009480.1 2461621 2462946 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(2461621..2462946) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173336 YP_001222917.1 CDS CMM_2172 NC_009480.1 2463108 2464241 R catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; N-succinyldiaminopimelate aminotransferase complement(2463108..2464241) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175139 YP_001222918.1 CDS fdxB NC_009480.1 2464238 2464558 R putative ferredoxin (YP_062518.1| ferredoxin [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629284.1| ferredoxin [Streptomyces coelicolor A3(2)]). pfam00037,Fer4, 4Fe-4S binding domain. Superfamily includes proteins containing domains which bind to iron-sulfur clusters.; Specificity unclear; hypothetical protein complement(2464238..2464558) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173389 YP_001222919.1 CDS CMM_2174 NC_009480.1 2464599 2465891 R putative fusion protein; conserved hypothetical protein, putative mycothiol biosynthesis + membrane protein (ZP_00057485.1| COG2120: Uncharacterized proteins,LmbE homologs [Thermobifida fusca]; NP_824314.1| hypothetical protein SAV3138 [Streptomyces avermitilis MA-4680]; YP_062519.1| hypothetical protein Lxx16250 [Leifsonia xyli subsp. xyli str. CTCB07]). pfam02585,DUF158, Uncharacterised LmbE-like protein, COG2120. pfam01284, MARVEL, Membrane-associating domain.; Function unclear; hypothetical protein complement(2464599..2465891) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172935 YP_001222920.1 CDS CMM_2175 NC_009480.1 2466135 2467046 D putative Fe2+ permease, OFeT family (NP_827101.1| putative membrane protein [Streptomyces avermitilis MA-4680]; YP_062520.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam03239, FTR1, Iron permease FTR1 family.; Specificity unclear; OFeT family Fe2+ permease 2466135..2467046 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174644 YP_001222921.1 CDS CMM_2176 NC_009480.1 2467123 2468340 D conserved secreted lipoprotein (YP_062521.1| lipoprotein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827103.1| putative lipoprotein [Streptomyces avermitilis MA-4680]). pfam04302, DUF451, Protein of unknown function (DUF451). Putative lipoprotein.; Function unclear; secreted lipoprotein 2467123..2468340 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173524 YP_001222922.1 CDS CMM_2177 NC_009480.1 2468340 2469671 D conserved hypothetical protein, putative Fe-dependant peroxidase (YP_062522.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827102.1| hypothetical protein SAV5925 [Streptomyces avermitilis MA-4680]). pfam04261, Dyp_perox, Dyp-type peroxidase family. This family of dye-decolourising peroxidases lack a typical heme-binding region.; Function unclear; putative Fe-dependent peroxidase 2468340..2469671 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175275 YP_001222923.1 CDS CMM_2178 NC_009480.1 2469708 2470217 R Hypothetical protein; hypothetical protein complement(2469708..2470217) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173713 YP_001222924.1 CDS bipA NC_009480.1 2470224 2472131 R GTP-binding protein typA/bipA homolog (YP_062523.1| GTP-binding protein elongation factor [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629261.1| putative GTP-binding protein [Streptomyces coelicolor A3(2)]; ZP_00058492.1| COG1217: Predicted membrane GTPase involved in stress response [Thermobifida fusca]). pfam00009,GTP_EFTU, Elongation factor Tu GTP binding domain. pfam03144, GTP_EFTU_D2, Elongation factor Tu domain 2. pfam00679, EFG_C, Elongation factor G C-terminus.; Specificity unclear; GTP-binding protein typA/bipA-like protein complement(2470224..2472131) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173749 YP_001222925.1 CDS CMM_2180 NC_009480.1 2472245 2474098 R putative peptide ABC transporter, binding protein (YP_062530.1| dipeptide porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_822049.1| putative solute-binding dependent transport lipoprotein [Streptomyces avermitilis MA-4680]; NP_217101.1| hypothetical protein Rv2585c [Mycobacterium tuberculosis H37Rv]). pfam00496, SBP_bac_5,Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative peptide ABC transporter substrate-binding protein complement(2472245..2474098) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173878 YP_001222926.1 CDS CMM_2181 NC_009480.1 2474197 2475888 R putative peptide ABC transporter, ATP-binding protein (duplicated ATPase domains) (YP_062526.1| oligopeptide porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696512.1| ATP binding protein of ABC transporter [Bifidobacterium longum NCC2705]; NP_773349.1| bll6709 [Bradyrhizobium japonicum]). InterPro: AAA ATPase superfamily; Specificity unclear; putative peptide ABC transporter ATP-binding protein complement(2474197..2475888) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173984 YP_001222927.1 CDS CMM_2182 NC_009480.1 2475960 2476565 D putative membrane protein (YP_062527.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056519.1| hypothetical membane-associated protein [Propionibacterium acnes KPA171202]).; Conserved hypothetical protein; hypothetical protein 2475960..2476565 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174441 YP_001222928.1 CDS CMM_2183 NC_009480.1 2476619 2477812 R putative peptide ABC transporter, permease component (YP_062528.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00056958.1| COG1173: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Thermobifida fusca]; AAG09259.1| EppC [EDTA-degrading bacterium BNC1]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative oligopeptide ABC transporter permease complement(2476619..2477812) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174156 YP_001222929.1 CDS CMM_2184 NC_009480.1 2477816 2479342 R putative peptide ABC transporter, permease component (YP_062529.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824223.1| putative peptide ABC transporter permease protein [Streptomyces avermitilis MA-4680]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative peptide ABC transporter permease complement(2477816..2479342) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173693 YP_001222930.1 CDS CMM_2185 NC_009480.1 2479521 2481356 R putative peptide ABC transporter, substrate-binding protein (YP_062530.1| dipeptide porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_822049.1| putative solute-binding dependent transport lipoprotein [Streptomyces avermitilis MA-4680]). pfam00496, SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative peptide ABC transporter substrate-binding protein complement(2479521..2481356) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174311 YP_001222931.1 CDS CMM_2186 NC_009480.1 2481646 2482461 D conserved membran protein (YP_062531.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625656.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam02517, Abi, CAAX amino terminal protease family. Members of this family are probably proteases; the family contains CAAX prenyl protease. prfB: peptide chain release factor 2; Conserved hypothetical protein; membrane protein 2481646..2482461 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174768 YP_001222932.1 CDS CMM_2187 NC_009480.1 2482570 2482977 D hypothetical protein 2482570..2482977 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175206 YP_001222933.1 CDS CMM_2188 NC_009480.1 2482974 2484596 D conserved membrane protein, putative transporter of the SSS family (ZP_00293132.1| COG4147: Predicted symporter [Thermobifida fusca]; NP_939157.1| Putative transport membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam00474, SSF, Sodium:solute symporter family. sss: SSS sodium solute transporter sup; Specificity unclear; SSS family transporter membrane protein 2482974..2484596 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174083 YP_001222934.1 CDS CMM_2189 NC_009480.1 2484641 2485513 R putative transcriptional regulator, RpiR family (CAF21466.1| transcriptional regulator, rpiR family [Corynebacterium glutamicum ATCC 13032]; NP_346833.1| Transcriptional regulator, RpiR family [Clostridium acetobutylicum]). pfam01418, HTH_6, Helix-turn-helix domain, rpiR family. pfam01380, SIS, SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. InterPro: SIS domain.; Specificity unclear; RpiR family transcriptional regulator complement(2484641..2485513) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174682 YP_001222935.1 CDS CMM_2190 NC_009480.1 2485500 2486306 R putative phosphate/phosphonate ABC transporter,permease component (CAF21467.1| ABC-type phosphate/phosphonate transport system, permease component [Corynebacterium glutamicum ATCC 13032]; NP_691520.1| alkylphosphonate ABC tranporter permease [Oceanobacillus iheyensis HTE831]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative phosphate/phosphonate ABC transporterpermease complement(2485500..2486306) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174128 YP_001222936.1 CDS CMM_2191 NC_009480.1 2486303 2487097 R putative phosphate/phosphonate ABC transporter,permease component (CAF21468.1| ABC-type phosphate/phosphonate transport system, permease component [Corynebacterium glutamicum ATCC 13032]; ZP_00239895.1| phosphonates transport system permease protein phnE [Bacillus cereus G9241]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative phosphate/phosphonate ABC transporterpermease complement(2486303..2487097) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173838 YP_001222937.1 CDS CMM_2192 NC_009480.1 2487094 2487915 R putative phosphate/phosphonate ABC transporter, ATP-binding protein (CAF21469.1| ABC-type phosphate/phosphonate transport system, ATPase component [Corynebacterium glutamicum ATCC 13032]; YP_039609.1| putative ABC transport ATP-binding protein [Staphylococcus aureus subsp. aureus MRSA252]).; Specificity unclear; putative phosphate/phosphonate ABC transporterATP-binding protein complement(2487094..2487915) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173239 YP_001222938.1 CDS CMM_2193 NC_009480.1 2487919 2488896 R putative phosphate/phosphonate ABC transporter,substrate-binding protein (CAF21470.1| ALKYLPHOSPHONATE ABC TRANPORTER (SECRETED PHOSPHATE-BINDING PROTEIN) [Corynebacterium glutamicum ATCC 13032]; NP_765811.1| alkylphosphonate ABC tranporter [Staphylococcus epidermidis ATCC 12228]).; Specificity unclear; putative phosphate/phosphonate ABC transportersubstrate-binding protein complement(2487919..2488896) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175538 YP_001222939.1 CDS CMM_2194 NC_009480.1 2488893 2489639 R putative hydrolase/phosphatase (CAF21471.1| PUTATIVE PHOSPHOGLYCOLATE PHOSPHATASE [Corynebacterium glutamicum ATCC 13032]; NP_879254.1| putative hydrolase [Bordetella pertussis Tohama I]). pfam00702, Hydrolase,haloacid dehalogenase-like hydrolase.; Function unclear; putative hydrolase/phosphatase complement(2488893..2489639) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174045 YP_001222940.1 CDS gcvP NC_009480.1 2489862 2492837 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(2489862..2492837) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173643 YP_001222941.1 CDS gcvH NC_009480.1 2492834 2493205 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(2492834..2493205) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175836 YP_001222942.1 CDS gcvT NC_009480.1 2493202 2494422 R putative aminomethyltransferase (Glycine cleavage system T protein) (YP_055458.1| glycine cleavage system protein T [Propionibacterium acnes KPA171202]; Q82JI2|GCST_STRAW Aminomethyltransferase (Glycine cleavage system T protein)). pfam01571, GCV_T, Glycine cleavage T-protein (aminomethyl transferase). InterPro: Glycine cleavage T-protein (aminomethyl transferase).; High confidence in function and specificity; putative aminomethyltransferase (glycine cleavage system T protein) complement(2493202..2494422) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175751 YP_001222943.1 CDS CMM_2198 NC_009480.1 2494792 2495247 R hypothetical protein complement(2494792..2495247) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175524 YP_001222944.1 CDS CMM_2199 NC_009480.1 2495374 2495745 D putative transcriptional regulator (NP_898715.1| putative regulator [Rhodococcus erythropolis]; ZP_00056896.1| COG3682: Predicted transcriptional regulator [Thermobifida fusca]). only weak similarity to: pfam01047, MarR, MarR family.; Specificity unclear; putative transcriptional regulator 2495374..2495745 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173515 YP_001222945.1 CDS CMM_2200 NC_009480.1 2495764 2496534 R putative copper resistance protein (AAS20064.1| hypothetical protein [Arthrobacter aurescens]; AAP73994.1| putative copper resistance protein (CopC) [Rhodococcus erythropolis]). pfam04234, CopC, Copper resistance protein CopC. CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule.; Conserved hypothetical protein; putative copper resistance protein complement(2495764..2496534) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173589 YP_001222946.1 CDS CMM_2201 NC_009480.1 2496636 2497937 D putative cysteine desulfurase (YP_061934.1| cysteine desulfurase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00294076.1| COG0520: Selenocysteine lyase [Thermobifida fusca]). pfam00266, Aminotran_5,Aminotransferase class-V. InterPro: Aminotransferase class-V.; Function unclear; putative cysteine desulfurase 2496636..2497937 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174606 YP_001222947.1 CDS CMM_2202 NC_009480.1 2497934 2498377 D conserved hypothetical protein (YP_061935.1| NifU homolog [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198827.3| COG0822: NifU homolog involved in Fe-S cluster formation [Kineococcus radiotolerans SRS30216]). pfam01592, NifU_N, NifU-like N terminal domain.; hypothetical protein 2497934..2498377 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173602 YP_001222948.1 CDS CMM_2203 NC_009480.1 2498457 2498852 D conserved hypothetical protein (ZP_00293644.1| COG3668: Plasmid stabilization system protein [Thermobifida fusca]; NP_961886.1| hypothetical protein MAP2952c [Mycobacterium avium subsp. paratuberculosis str. k10]).; hypothetical protein 2498457..2498852 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173950 YP_001222949.1 CDS CMM_2204 NC_009480.1 2498892 2501741 R putative glycosyl hydrolase containing C-terminal fibronectin/RTX domain (NP_811025.1| conserved hypothetical protein [Bacteroides thetaiotaomicron VPI-5482]; NP_695377.1| very narrowly conserved hypothetical protein [Bifidobacterium longum NCC2705]). , weak similarity to: COG3507, XynB, Beta-xylosidase; hypothetical protein complement(2498892..2501741) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175544 YP_001222950.1 CDS CMM_2205 NC_009480.1 2501901 2502455 R putative acetyltransferase (ZP_00209608.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Magnetospirillum magnetotacticum MS-1]; ZP_00293653.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Thermobifida fusca]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(2501901..2502455) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175823 YP_001222951.1 CDS CMM_2206 NC_009480.1 2502502 2503578 D hypothetical protein 2502502..2503578 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173246 YP_001222952.1 CDS CMM_2207 NC_009480.1 2503597 2504160 R hypothetical protein complement(2503597..2504160) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173210 YP_001222953.1 CDS CMM_2208 NC_009480.1 2504219 2504623 R hypothetical protein (only weak similarity to: NP_628387.1| hypothetical protein SCO4212 [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(2504219..2504623) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174198 YP_001222954.1 CDS CMM_2209 NC_009480.1 2504846 2505268 D hypothetical transcriptional regulator, MarR family (only weak similarities: NP_470525.1| ; ZP_00088731.2| COG1846: Transcriptional regulators [Azotobacter vinelandii]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Hypothetical protein; MarR family transcriptional regulator 2504846..2505268 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174648 YP_001222955.1 CDS CMM_2210 NC_009480.1 2505311 2506036 R conserved hypothetical protein, hypothetical two-component response regulator (NP_769771.1| two-component response regulator [Bradyrhizobium japonicum]; P_00217823.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Burkholderia cepacia R18194]). InterPro: Response regulator receiver domain pfam00072, Response_reg,Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems.; hypothetical protein complement(2505311..2506036) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175510 YP_001222956.1 CDS CMM_2211 NC_009480.1 2506159 2506773 R hypothetical protein complement(2506159..2506773) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173276 YP_001222957.1 CDS CMM_2212 NC_009480.1 2506863 2508329 D putative amino acid permease, APC family (ZP_00187138.1| COG0531: Amino acid transporters [Rubrobacter xylanophilus DSM 9941]; ZP_00127340.1| COG0531: Amino acid transporters [Pseudomonas syringae pv. syringae B728a]). pfam00324, AA_permease, Amino acid permease. InterPro: Amino acid permease.; Specificity unclear; amino acid permease 2506863..2508329 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173143 YP_001222958.1 CDS CMM_2213 NC_009480.1 2508333 2508782 D conserved hypothetical protein belonging to universal stress protein family (YP_094969.1| universal stress protein A (UspA) [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]; ZP_00359330.1| COG0589: Universal stress protein UspA and related nucleotide-binding proteins [Chloroflexus aurantiacus]). pfam00582,Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents.; Function unclear; hypothetical protein 2508333..2508782 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173102 YP_001222959.1 CDS CMM_2214 NC_009480.1 2508793 2509215 R putative thiol-disulfide oxidoreductase (YP_061316.1| thiol:disulfide interchange protein [Leifsonia xyli subsp. xyli str. CTCB07]; AAS20062.1| hypothetical protein [Arthrobacter aurescens]). InterPro: Thioredoxin.; Function unclear; putative thiol-disulfide oxidoreductase complement(2508793..2509215) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173078 YP_001222960.1 CDS CMM_2215 NC_009480.1 2509535 2509981 D hypothetical protein with peptidoglycan binding domain pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function.; hypothetical protein 2509535..2509981 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174015 YP_001222961.1 CDS CMM_2216 NC_009480.1 2510037 2510237 R hypothetical protein (CAD47973.1| hypothetical protein [Arthrobacter nicotinovorans]). mobB: molybdopterin-guanine dinucleotide; hypothetical protein complement(2510037..2510237) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173978 YP_001222962.1 CDS gabP NC_009480.1 2510689 2512101 D putative gamma-aminobutyrate permease, APC family (NP_215036.1| Gamma-aminobutyrate permease [Mycobacterium tuberculosis H37Rv]; T44252 transport protein homolog [imported] - Arthrobacter sp. (strain TE1826)). pfam00324,AA_permease, Amino acid permease. InterPro: Amino acid permease.; Specificity unclear; gamma-aminobutyrate permease 2510689..2512101 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173291 YP_001222963.1 CDS CMM_2218 NC_009480.1 2512152 2512844 D conserved hypothetical protein, phosphoglycerate mutase family (NP_625941.1| putative phosphatase [Streptomyces coelicolor A3(2)]; NP_336663.1| phosphoglycerate mutase family protein [Mycobacterium tuberculosis CDC1551]). pfam00300, PGAM, Phosphoglycerate mutase family. InterPro: Phosphoglycerate mutase family; Function unclear; hypothetical protein 2512152..2512844 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174552 YP_001222964.1 CDS CMM_2219 NC_009480.1 2512868 2513431 D conserved hypothetical protein (NP_827821.1| hypothetical protein SAV6646 [Streptomyces avermitilis MA-4680]; NP_855807.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97]).; hypothetical protein 2512868..2513431 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173554 YP_001222965.1 CDS CMM_2220 NC_009480.1 2513431 2514198 D conserved hypothetical protein (CAB08660.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_827822.1| hypothetical protein SAV6646 [Streptomyces avermitilis MA-4680]). , pfam00454,PI3_PI4_kinase, Phosphatidylinositol 3- and 4-kinase.; hypothetical protein 2513431..2514198 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173689 YP_001222966.1 CDS CMM_2221 NC_009480.1 2514367 2515011 D hypothetical protein , weak similarity to: COG4969,PilA, Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; hypothetical protein 2514367..2515011 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172985 YP_001222967.1 CDS CMM_2222 NC_009480.1 2515482 2515967 R hypothetical protein (AAN12593.1| gp32 [Mycobacteriophage Che9c]; YP_113190.1| Hypothetical protein MCA0678 [Methylococcus capsulatus str. Bath]). ,pfam06114, DUF955, Domain of unknown function (DUF955). Family of bacterial and viral proteins with undetermined function.; hypothetical protein complement(2515482..2515967) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173194 YP_001222968.1 CDS CMM_2223 NC_009480.1 2516137 2517210 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(2516137..2517210) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173129 YP_001222969.1 CDS CMM_2224 NC_009480.1 2517310 2517939 D putative 3'-5' exonuclease (YP_062544.1| DNA polymerase III, epsilon subunit [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293652.1| COG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [Thermobifida fusca]). pfam00929, Exonuc_X-T, Exonuclease. This family includes a variety of exonuclease proteins,such as ribonuclease T and the epsilon subunit of DNA polymerase III.; Function unclear; hypothetical protein 2517310..2517939 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173060 YP_001222970.1 CDS CMM_2225 NC_009480.1 2518006 2519385 D conserved hypothetical protein (YP_062546.1| Hypothetical protein Lxx16660 [Leifsonia xyli subsp. xyli str. CTCB07]; Q9CLG7|RMUC_PASMU DNA recombination protein rmuC homolog; ZP_00134138.1| COG1322: Uncharacterized protein conserved in bacteria [Actinobacillus pleuropneumoniae serovar 1 str. 4074]). pfam02646, RmuC,RmuC family. This family contains several bacterial RmuC DNA recombination proteins. The function of the RMUC protein is unknown but it is suspected that it is either a structural protein that protects DNA against nuclease action, or is itself involved in DNA cleavage at the regions of DNA secondary structures.; Family membership; hypothetical protein 2518006..2519385 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173070 YP_001222971.1 CDS fbaA NC_009480.1 2519491 2520516 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 2519491..2520516 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173066 YP_001222972.1 CDS CMM_2227 NC_009480.1 2520612 2521448 R hypothetical membrane protein (YP_062549.1| Hypothetical protein Lxx16690 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(2520612..2521448) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173171 YP_001222973.1 CDS ispH NC_009480.1 2521445 2522434 R catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase complement(2521445..2522434) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175201 YP_001222974.1 CDS xseA NC_009480.1 2522582 2523898 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2522582..2523898 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174783 YP_001222975.1 CDS xseB NC_009480.1 2523909 2524151 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 2523909..2524151 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174106 YP_001222976.1 CDS CMM_2231 NC_009480.1 2524154 2524861 D conserved hypothetical protein (NP_629200.1| putative secreted protein [Streptomyces coelicolor A3(2)]; ZP_00225733.1| hypothetical protein Krad06004532 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 2524154..2524861 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174125 YP_001222977.1 CDS cynT NC_009480.1 2524858 2525520 D putative carbonic anhydrase (YP_062554.1| carbonic anhydrase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_338238.1| carbonic anhydrase [Mycobacterium tuberculosis CDC1551]). pfam00484, Pro_CA, Carbonic anhydrase.; Function unclear; putative carbonic anhydrase 2524858..2525520 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173730 YP_001222978.1 CDS fumC NC_009480.1 2525602 2527026 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 2525602..2527026 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174358 YP_001222979.1 CDS CMM_2234 NC_009480.1 2527058 2527327 D hypothetical protein 2527058..2527327 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174352 YP_001222980.1 CDS CMM_2235 NC_009480.1 2527411 2528766 R putative ATPase (YP_062557.1| PhoH-like protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824412.1| putative ATP-binding protein [Streptomyces avermitilis MA-4680]). pfam01850, PIN, PIN domain. This PIN (PilT N terminus) domain is a compact domain of about 100 amino acids. pfam02562, PhoH, PhoH-like protein. PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation.; Function unclear; putative ATPase complement(2527411..2528766) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175344 YP_001222981.1 CDS uppS2 NC_009480.1 2528994 2529779 R putative undecaprenyl diphosphate synthase (YP_062559.1| undecaprenyl pyrophosphate synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; BAD59670.1| putative undecaprenyl pyrophosphate synthetase [Nocardia farcinica]). , pfam01255, UPP_synthetase, Putative undecaprenyl diphosphate synthase. Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase. , uppS: undecaprenyl diphosphate synthas; High confidence in function and specificity; putative undecaprenyl diphosphate synthase complement(2528994..2529779) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175916 YP_001222982.1 CDS CMM_2237 NC_009480.1 2529861 2530616 D conserved membrane protein, HlyIII family (YP_062560.1| hemolysin III family protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629130.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; NP_696186.1| conserved hypothetical protein [Bifidobacterium longum NCC2705]). , pfam03006, UPF0073,Uncharacterised protein family (Hly-III / UPF0073). Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus. It is not clear if all the members of this family are hemolysins.; Function unclear; HlyIII family membrane protein 2529861..2530616 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173254 YP_001222983.1 CDS CMM_2238 NC_009480.1 2530641 2532020 R putative sugar ABC transporter, substrate-binding protein (ZP_00049406.2| COG1653: ABC-type sugar transport system, periplasmic component [Magnetospirillum magnetotacticum MS-1]; CAB03653.1| PROBABLE Sn-GLYCEROL-3-PHOSPHATE-BINDING LIPOPROTEIN UGPB [Mycobacterium tuberculosis H37Rv]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter substrate-binding protein complement(2530641..2532020) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174932 YP_001222984.1 CDS CMM_2239 NC_009480.1 2532082 2532996 R putative glycerol ABC transporter, permease component (ZP_00356561.1| COG0395: ABC-type sugar transport system, permease component [Chloroflexus aurantiacus]; NP_600603.1| ABC-type transporter, permease component [Corynebacterium glutamicum ATCC 13032]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative glycerol ABC transporter permease complement(2532082..2532996) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173918 YP_001222985.1 CDS CMM_2240 NC_009480.1 2532993 2533982 R putative glycerol ABC transporter, permease component (CAB03651.1| PROBABLE Sn-GLYCEROL-3-PHOSPHATE TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER UGPA [Mycobacterium tuberculosis H37Rv]; NP_738124.1| putative ABC transporter permease protein [Corynebacterium efficiens YS-314]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative glycerol ABC transporter permease complement(2532993..2533982) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175228 YP_001222986.1 CDS CMM_2241 NC_009480.1 2534162 2534506 R hypothetical membrane protein (AAS20077.1| membrane protein [Arthrobacter aurescens]; YP_062561.1| Hypothetical protein Lxx16880 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(2534162..2534506) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173891 YP_001222987.1 CDS CMM_2242 NC_009480.1 2534506 2535387 R conserved hypothetical protein (NP_737662.1| hypothetical protein CE1052 [Corynebacterium efficiens YS-314]; CAA17198.1| Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase)[Mycobacterium tuberculosis H37Rv]). pfam02585, DUF158, Uncharacterised LmbE-like protein, COG2120. 3mg: DNA-3-methyladenine glycosylase; hypothetical protein complement(2534506..2535387) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174635 YP_001222988.1 CDS CMM_2243 NC_009480.1 2535454 2535936 D hypothetical protein (YP_055275.1| hypothetical protein PPA0562 [Propionibacterium acnes KPA171202]; BAD59677.1| hypothetical protein [Nocardia farcinica]).; hypothetical protein 2535454..2535936 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174238 YP_001222989.1 CDS greA NC_009480.1 2535997 2536485 D transcription elongation factor (Transcript cleavage factor greA)(YP_062562.1| transcription elongation factor [Leifsonia xyli subsp. xyli str. CTCB07]; Q9ADK2|GREA_STRCO Transcription elongation factor greA (Transcript cleavage factor greA)). pfam03449,GreA_GreB_N, Prokaryotic transcription elongation factor,GreA/GreB, N-terminal domain. pfam01272, GreA_GreB,Prokaryotic transcription elongation factor, GreA/GreB, C-terminal domain.; High confidence in function and specificity; transcription elongation factor GreA 2535997..2536485 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174370 YP_001222990.1 CDS ilvA NC_009480.1 2536552 2537820 R catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase complement(2536552..2537820) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174762 YP_001222991.1 CDS CMM_2246 NC_009480.1 2537925 2539160 R conserved membrane protein, AI-E2 family (YP_062564.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; BAD60345.1| hypothetical protein [Nocardia farcinica])., pfam01594, UPF0118, Domain of unknown function DUF20. This transmembrane region is found in putative permeases and predicted transmembrane proteins it has no known function.; AI-E2 family membrane protein complement(2537925..2539160) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173535 YP_001222992.1 CDS CMM_2247 NC_009480.1 2539261 2540511 D conserved hypothetical protein (YP_062567.1| Hypothetical protein Lxx16960 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00194535.1| COG3214: Uncharacterized protein conserved in bacteria [Mesorhizobium sp. BNC1]). pfam06224, DUF1006, Protein of unknown function (DUF1006). Family of conserved bacterial proteins with unknown function. aroC: chorismate synthase; hypothetical protein 2539261..2540511 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175039 YP_001222993.1 CDS CMM_2248 NC_009480.1 2540522 2541088 R conserved hypothetical protein (YP_062568.1| LemA-like protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787140.1| hypothetical protein TWT012 [Tropheryma whipplei str. Twist]). pfam04011, LemA, LemA family. The members of this family are related to the LemA protein.; hypothetical protein complement(2540522..2541088) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173873 YP_001222994.1 CDS bglL NC_009480.1 2541091 2542593 R putative beta-glucosidase (Gentiobiase) (Cellobiase) (NP_826775.1| putative beta-glucosidase [Streptomyces avermitilis MA-4680]; AAN05440.1| beta-glycosidase [Thermus filiformis]). pfam00232,Glyco_hydro_1, Glycosyl hydrolase family 1. InterPro: Glycoside hydrolase family 1; Specificity unclear; putative beta-glucosidase complement(2541091..2542593) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175028 YP_001222995.1 CDS CMM_2250 NC_009480.1 2542734 2545028 D Region start changed from 2542743 to 2542734 (9 bases); hypothetical protein 2542734..2545028 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175420 YP_001222996.1 CDS CMM_2251 NC_009480.1 2545161 2546603 D putative amino acid permease, APC family (NP_625236.1| putative amino acid transporter protein [Streptomyces coelicolor A3(2)]; ZP_00187751.1| COG0531: Amino acid transporters [Rubrobacter xylanophilus DSM 9941]). pfam00324, AA_permease, Amino acid permease.; Specificity unclear; amino acid permease 2545161..2546603 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173721 YP_001222997.1 CDS CMM_2252 NC_009480.1 2546679 2547620 R conserved hypothetical protein (ZP_00227307.1| hypothetical protein Krad06001366 [Kineococcus radiotolerans SRS30216]; ZP_00029551.1| hypothetical protein [Burkholderia fungorum]; NP_051649.1| dessication-associated protein [Deinococcus radiodurans R1]).; Function unclear; hypothetical protein complement(2546679..2547620) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175865 YP_001222998.1 CDS CMM_2253 NC_009480.1 2547805 2550366 R conserved hypothetical protein contains two domains: N-terminal: putative endoglucanase domain (CAD47882.1| hypothetical protein [Arthrobacter nicotinovorans]). C-terminal: pfam01757, Acyl_transf_3,Acyltransferase family. This family includes a range of acyltransferase enzymes (NP_946456.1| possible OpgC protein, require for succinylation of osmoregulated periplasmic glucans [Rhodopseudomonas palustris CGA009]; NP_771053.1| bll4413 [Bradyrhizobium japonicum USDA 110]).; Function unclear; hypothetical protein complement(2547805..2550366) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175084 YP_001222999.1 CDS CMM_2254 NC_009480.1 2550438 2550872 R putative anti-sigma regulatory factor (Ser/Thr protein kinase) (NP_737815.1| hypothetical protein [Corynebacterium efficiens YS-314]; NP_681341.1| sigma-B activity negative regulator [Thermosynechococcus elongatus BP-1]).; Function unclear; putative anti-sigma regulatory factor (Ser/Thr protein kinase) complement(2550438..2550872) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174904 YP_001223000.1 CDS CMM_2255 NC_009480.1 2550877 2551215 R putative anti-sigma factor antagonist (ZP_00357937.1| COG1366: Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) [Chloroflexus aurantiacus]; NP_737814.1| putative anti-sigma factor antagonist [Corynebacterium efficiens YS-314]). pfam01740,STAS, STAS domain. The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.; Function unclear; putative anti-sigma factor antagonist complement(2550877..2551215) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175307 YP_001223001.1 CDS CMM_2256 NC_009480.1 2551212 2553203 R putative glycosyl transferase (NP_737812.1 + NP_737813.1|| putative cellulose synthase catalytic subunit [Corynebacterium efficiens YS-314]; ZP_00020665.2| COG1215: Glycosyltransferases, probably involved in cell wall biogenesis [Chloroflexus aurantiacus]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose,dolichol phosphate and teichoic acids. only weak similarity to: pfam03552, Cellulose_synt, Cellulose synthase.; Function unclear; putative glycosyl transferase complement(2551212..2553203) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172927 YP_001223002.1 CDS CMM_2257 NC_009480.1 2553200 2554396 R Sensory box histidine kinase/response regulator (NP_737811.1| putative regulatory protein [Corynebacterium efficiens YS-314]). , contains two domains: N-terminal,pfam01590, GAF, GAF domain. Domain present in phytochromes and cGMP-specific phosphodiesterases (ZP_00265410.1| COG2199: FOG: GGDEF domain [Pseudomonas fluorescens PfO-1]; ZP_00052301.2| COG2203: FOG: GAF domain [Magnetospirillum magnetotacticum MS-1]). , C-terminal,COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; smart00331, PP2C_SIG, Sigma factor PP2C-like phosphatases (ZP_00187433.1| COG2208: Serine phosphatase RsbU,regulator of sigma subunit; ZP_00356055.1| COG3706: Response regulator containing a CheY-like receiver domain and a GGDEF domain [Chloroflexus aurantiacus]).; Conserved hypothetical protein; putative protein kinase/phosphatase regulator hybrid protein complement(2553200..2554396) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173820 YP_001223003.1 CDS CMM_2258 NC_009480.1 2554575 2555729 D putative membrane-bound acyltransferase (ZP_00107696.1| COG1835: Predicted acyltransferases [Nostoc punctiforme PCC 73102]; AAO54531.1| acyltransferase family protein [Pseudomonas syringae pv. tomato str. DC3000]). pfam01757, Acyl_transf_3,Acyltransferase family. This family includes a range of acyltransferase enzymes.; Specificity unclear; putative membrane-bound acyltransferase 2554575..2555729 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175833 YP_001223004.1 CDS CMM_2259 NC_009480.1 2555945 2557432 R putative NADH dehydrogenase (YP_062580.1| NADH dehydrogenase, type 2 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_631162.1| putative dehydrogenase [Streptomyces coelicolor A3(2)]). , pfam00070, Pyr_redox,Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases.; Specificity unclear; putative NADH dehydrogenase complement(2555945..2557432) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174832 YP_001223005.1 CDS CMM_2260 NC_009480.1 2557470 2558753 R putative serine peptidase, family S8 (YP_062581.1| serine protease [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827909.1| putative secreted serine proteinase [Streptomyces avermitilis MA-4680]). pfam00082,Peptidase_S8, Subtilase family. Subtilases are a family of serine proteases. InterPro: Serine proteases subtilase family.; Function unclear; serine peptidase complement(2557470..2558753) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174115 YP_001223006.1 CDS CMM_2261 NC_009480.1 2558750 2559265 R conserved hypothetical protein (YP_062582.1| Hypothetical protein Lxx17160 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789712.1| hypothetical protein TW791 [Tropheryma whipplei TW08/27]). pfam04417, DUF501, Protein of unknown function (DUF501). Family of uncharacterised bacterial proteins. TIGR00162: conserved hypothetical protei; hypothetical protein complement(2558750..2559265) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175003 YP_001223007.1 CDS CMM_2262 NC_009480.1 2559262 2559834 R conserved hypothetical protein (YP_062583.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824709.1| hypothetical protein SAV3532 [Streptomyces avermitilis MA-4680]). pfam04977, DivIC,Septum formation initiator. DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation.; hypothetical protein complement(2559262..2559834) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175810 YP_001223008.1 CDS eno NC_009480.1 2559922 2561202 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(2559922..2561202) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175418 YP_001223009.1 CDS hisS NC_009480.1 2561319 2562626 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2561319..2562626) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174037 YP_001223010.1 CDS CMM_2265 NC_009480.1 2562639 2563280 R putative transcriptional regulator, TetR-family (YP_061371.1| transcriptional regulator, TetR family [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228510.1| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_824937.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator complement(2562639..2563280) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175200 YP_001223011.1 CDS CMM_2266 NC_009480.1 2563435 2564199 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase complement(2563435..2564199) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175103 YP_001223012.1 CDS nhaA2 NC_009480.1 2564307 2565536 D putative Na+/H+ antiporter, NhaA family (NP_789716.1| putative sodium/proton antiporter [Tropheryma whipplei TW08/27]; AAL15616.1| sodium/proton antiporter [Streptomyces antibioticus]). , pfam06965,Na_H_antiport_1, Na+/H+ antiporter 1. , InterPro: Na+/H+ exchanger.; High confidence in function and specificity; NhaA family Na+/H+ antiporter 2564307..2565536 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175190 YP_001223013.1 CDS mfdA NC_009480.1 2565560 2569192 R putative transcription-repair coupling factor (superfamily II helicase) (BAD59727.1| putative transcription-repair coupling factor [Nocardia farcinica]; ZP_00059332.1| COG1197: Transcription-repair coupling factor (superfamily II helicase) [Thermobifida fusca]; NP_824726.1| putative transcriptional-repair coupling factor [Streptomyces avermitilis MA-4680]). NECESSARY FOR STRAND-SPECIFIC REPAIR. A LESION IN THE TEMPLATE STRAND BLOCKS THE RNA POLYMERASE COMPLEX (RNAP). THE RNAP-DNA-RNA COMPLEX IS SPECIFICALLY RECOGNIZED BY TRCF WHICH RELEASES RNAP AND THE TRUNCATED TRANSCRIPT; THE TCRF MAY REPLACE RNAP AT THE LESION SITE AND THEN RECRUIT THE UVRA/B/C REPAIR SYSTEM (BY SIMILARITY). pfam02559,CarD_TRCF, CarD-like/TRCF domain. pfam00270, DEAD,DEAD/DEAH box helicase. pfam00271, Helicase_C, Helicase conserved C-terminal domain. pfam03461, TRCF, TRCF domain. InterPro: Transcription-repair coupling factor.; High confidence in function and specificity; putative transcription-repair coupling factor complement(2565560..2569192) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174686 YP_001223014.1 CDS pthA NC_009480.1 2569281 2569868 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(2569281..2569868) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173869 YP_001223015.1 CDS rplY NC_009480.1 2570009 2570653 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc complement(2570009..2570653) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175035 YP_001223016.1 CDS CMM_2271 NC_009480.1 2570824 2572833 R putative gluconokinase/dehydrogenase two-domain protein N-terminal: COG3265, GntK, Gluconate kinase (NP_738994.1| putative gluconokinase [Corynebacterium efficiens YS-314]; ZP_00057417.1| COG3265: Gluconate kinase [Thermobifida fusca]). C-terminal: COG0673, MviM,Predicted dehydrogenases and related proteins; pfam01408,GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold, pfam02894, GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain. (NP_622316.1| predicted dehydrogenases and related proteins [Thermoanaerobacter tengcongensis]; NP_782809.1| lipopolysaccharide biosynthesis protein [Clostridium tetani E88]). InterPro: Shikimate kinase; Function unclear; putative gluconokinase/dehydrogenase complement(2570824..2572833) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175399 YP_001223017.1 CDS gndA2 NC_009480.1 2572917 2574371 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2572917..2574371 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174551 YP_001223018.1 CDS CMM_2273 NC_009480.1 2574441 2574815 D hypothetical protein (YP_062601.1| Hypothetical protein Lxx17390 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2574441..2574815 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173364 YP_001223019.1 CDS prsA NC_009480.1 2574861 2575838 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(2574861..2575838) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173779 YP_001223020.1 CDS glmU NC_009480.1 2575853 2577397 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(2575853..2577397) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175349 YP_001223021.1 CDS CMM_2276 NC_009480.1 2577650 2578153 D putative transcriptional regulator, MarR family (YP_062606.1| transcriptional regulator, MarR family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627350.1| putative MarR-family regulator [Streptomyces coelicolor A3(2)]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 2577650..2578153 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175777 YP_001223022.1 CDS CMM_2277 NC_009480.1 2578182 2578538 R conserved hypothetical protein, putative DNA-binding protein (ZP_00352245.1| COG1734: DnaK suppressor protein [Kineococcus radiotolerans SRS30216]; ZP_00238743.1| DnaK suppressor protein [Bacillus cereus G9241]). pfam01258, zf-dskA_traR, Prokaryotic dksA/traR C4-type zinc finger.; putative DNA-binding protein complement(2578182..2578538) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175224 YP_001223023.1 CDS CMM_2278 NC_009480.1 2578549 2579556 R putative monooxygenase (NP_601510.1| coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase [Corynebacterium glutamicum ATCC 13032]; NP_767884.1| flavin dependant oxidoreductase [Bradyrhizobium japonicum USDA 110]). pfam00296,Bac_luciferase, Luciferase-like monooxygenase.; Function unclear; putative monooxygenase complement(2578549..2579556) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174221 YP_001223024.1 CDS CMM_2279 NC_009480.1 2579559 2580359 R conserved membrane protein, LysE transporter family (CAA98398.1| PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_638302.1| membrane transport protein [Xanthomonas campestris pv. campestris str. ATCC 33913]). pfam01810, LysE, LysE type translocator. This family consists of various hypothetical proteins and an l-lysine exporter LysE from Corynebacterium glutamicum which is proposed to be the first of a novel family of translocators.; Function unclear; amino acid transporter LysE complement(2579559..2580359) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175326 YP_001223025.1 CDS CMM_2280 NC_009480.1 2580429 2581325 D putative transcriptional regulator, LysR family (NP_822296.1| putative LysR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; YP_116352.1| putative transcriptional regulator [Nocardia farcinica]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466,LysR_substrate, LysR substrate binding domain.; Specificity unclear; LysR family transcriptional regulator 2580429..2581325 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174836 YP_001223026.1 CDS CMM_2281 NC_009480.1 2581363 2582022 R putative metal ABC transporter , permease component (YP_062479.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00121550.1| COG2011: ABC-type metal ion transport system, permease component [Bifidobacterium longum DJO10A]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative metal ABC transporter permease complement(2581363..2582022) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175702 YP_001223027.1 CDS CMM_2282 NC_009480.1 2582024 2583061 R putative metal ABC transporter , ATP-binding protein (YP_062480.1| glycine betaine/proline porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696132.1| ATP binding protein of ABC transporter [Bifidobacterium longum NCC2705]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative metal ABC transporter ATP-binding protein complement(2582024..2583061) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174747 YP_001223028.1 CDS CMM_2283 NC_009480.1 2583058 2583990 R putative metal ABC transporter, substrate-binding protein (ZP_00121548.1| COG1464: ABC-type metal ion transport system, periplasmic component/surface antigen [Bifidobacterium longum DJO10A]; YP_120623.1| putative lipoprotein [Nocardia farcinica]). pfam03180,Lipoprotein_9, NLPA lipoprotein. This family of bacterial lipoproteins contains several antigenic members, that may be involved in bacterial virulence. Their precise function is unknown. However they are probably distantly related to pfam00497 which are solute binding proteins.; Specificity unclear; putative metal ABC transporter substrate-binding protein complement(2583058..2583990) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174423 YP_001223029.1 CDS CMM_2284 NC_009480.1 2584336 2585238 D hypothetical protein 2584336..2585238 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174181 YP_001223030.1 CDS CMM_2285 NC_009480.1 2585251 2587068 R putative ABC transporter, duplicated ATP-binding protein (YP_062608.1| oleandomycin resistance ATPase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_960308.1| hypothetical protein MAP1374c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00059317.1| COG0488: ATPase components of ABC transporters with duplicated ATPase domains [Thermobifida fusca]). pfam00005, ABC_tran,ABC transporter (twice). InterPro: AAA ATPase superfamily.; Specificity unclear; putative ABC transporter duplicated ATP-binding protein complement(2585251..2587068) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174627 YP_001223031.1 CDS intA NC_009480.1 2587139 2588842 D putative DNA recombinase/integrase (BAA07372.1| ORF469 protein [Bacteriophage R4]; CAB09083.1| Probable phiRv1 integrase [Mycobacterium tuberculosis H37Rv]; NP_825645.1| putative integrase/recombinase [Streptomyces avermitilis MA-4680]).; Specificity unclear; putative integrase/recombinase 2587139..2588842 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173852 YP_001223032.1 CDS CMM_2287 NC_009480.1 2589829 2591448 R conserved hypothetical protein, ftsK homolog (NP_902149.1| cell division ftsk transmembrane protein [Chromobacterium violaceum ATCC 12472]; ZP_00217369.1| COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins [Burkholderia cepacia R18194]). pfam01580,FtsK_SpoIIIE, FtsK/SpoIIIE family. FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids, termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif.; Family membership; hypothetical protein complement(2589829..2591448) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175958 YP_001223033.1 CDS CMM_2288 NC_009480.1 2591441 2591923 R hypothetical protein complement(2591441..2591923) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174236 YP_001223034.1 CDS CMM_2289 NC_009480.1 2592071 2593186 R hypothetical protein complement(2592071..2593186) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175169 YP_001223035.1 CDS CMM_2290 NC_009480.1 2594184 2594678 D putative endonuclease (NP_821177.1| putative endonuclease VII [Streptomyces avermitilis MA-4680]; AAN12731.1| gp89 [Mycobacteriophage Omega]) pfam02945,Endonuclease_7, Recombination endonuclease VII.; Function unclear; putative endonuclease 2594184..2594678 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174942 YP_001223036.1 CDS CMM_2291 NC_009480.1 2595263 2596027 R putative endonuclease (NP_487703.1| unknown protein [Nostoc sp. PCC 7120]; CAD54902.1| putative lysogenic conversion protein [Bacteriophage P2-EC46]). pfam01844,HNH, HNH endonuclease.; Hypothetical protein; putative endonuclease complement(2595263..2596027) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174704 YP_001223037.1 CDS CMM_2292 NC_009480.1 2596073 2597857 R hypothetical protein (NP_744426.1| hypothetical protein PP2277 [Pseudomonas putida KT2440]); hypothetical protein complement(2596073..2597857) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174504 YP_001223038.1 CDS CMM_2293 NC_009480.1 2598067 2598270 D hypothetical protein 2598067..2598270 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175012 YP_001223039.1 CDS CMM_2294 NC_009480.1 2598267 2598668 D hypothetical protein 2598267..2598668 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174255 YP_001223040.1 CDS CMM_2295 NC_009480.1 2599259 2599699 D hypothetical secreted protein, putative pilin (NP_935571.1| type IV pilin PilA [Vibrio vulnificus YJ016]; ZP_00224593.1| COG4969: Tfp pilus assembly protein, major pilin PilA [Burkholderia cepacia R1808]). weak similarity to: COG4969, PilA, Tfp pilus assembly protein, major pilin PilA; pfam00114, Pilin, Pilin (bacterial filament).; Hypothetical protein; pilin 2599259..2599699 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175337 YP_001223041.1 CDS CMM_2296 NC_009480.1 2600459 2601316 R hypothetical protein complement(2600459..2601316) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174581 YP_001223042.1 CDS CMM_2297 NC_009480.1 2602014 2602694 D putative recombinase/resolvase (AAG24402.1| site-specific recombinase [Actinobacillus actinomycetemcomitans]; CAE46772.1| recombinase [Yersinia enterocolitica]). pfam00239, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface.; Hypothetical protein; putative resolvase 2602014..2602694 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175082 YP_001223043.1 CDS CMM_2298 NC_009480.1 2602691 2602870 D hypothetical protein 2602691..2602870 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175340 YP_001223044.1 CDS CMM_2299 NC_009480.1 2602854 2603441 D hypothetical protein (only weak similarities to endonucleases: pfam01541, GIY-YIG, GIY-YIG catalytic domain. This domain called GIY-YIG is found in the amino terminal region of excinuclease abc subunit c (uvrC),bacteriophage T4 endonucleases segA, segB, segC, segD and segE; it is also found in putative endonucleases encoded by group I introns of fungi and phage; AAD42655.2| SegB homing endonuclease [Enterobacteria phage T4]).; hypothetical protein 2602854..2603441 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174715 YP_001223045.1 CDS CMM_2300 NC_009480.1 2603570 2604280 D hypothetical protein 2603570..2604280 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175977 YP_001223046.1 CDS CMM_2301 NC_009480.1 2605923 2606174 D hypothetical protein 2605923..2606174 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173425 YP_001223047.1 CDS CMM_2302 NC_009480.1 2606235 2606807 R hypothetical protein (weak similarities to: NP_607806.1| conserved hypothetical phage protein [Streptococcus pyogenes MGAS8232]). weak similarity to: smart00470, ParB, ParB-like nuclease domain.; hypothetical protein complement(2606235..2606807) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175654 YP_001223048.1 CDS CMM_2303 NC_009480.1 2607098 2607688 R hypothetical protein complement(2607098..2607688) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174168 YP_001223049.1 CDS CMM_2304 NC_009480.1 2607802 2608245 R hypothetical protein complement(2607802..2608245) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175602 YP_001223050.1 CDS CMM_2305 NC_009480.1 2609051 2610355 D putative multidrug-efflux MFS permease (NP_792949.1| multidrug resistance protein, putative [Pseudomonas syringae pv. tomato str. DC3000]; ZP_00363247.1| COG0477: Permeases of the major facilitator superfamily [Polaromonas sp. JS666]). pfam00083, Sugar_tr,Sugar (and other) transporter. InterPro: General substrate transporters.; Specificity unclear; putative multidrug-efflux MFS permease 2609051..2610355 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173935 YP_001223051.1 CDS CMM_2306 NC_009480.1 2610519 2610689 D hypothetical membrane protein (YP_062968.1| Hypothetical protein Lxx21740 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2610519..2610689 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174163 YP_001223052.1 CDS CMM_2307 NC_009480.1 2610836 2612569 D putative memebrane protein (YP_061591.1| Hypothetical protein Lxx05060 [Leifsonia xyli subsp. xyli str. CTCB07]; BAA19642.1| unnamed protein product [Actinobacillus actinomycetemcomitans]).; hypothetical protein 2610836..2612569 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173478 YP_001223053.1 CDS CMM_2308 NC_009480.1 2612566 2613045 D putative membrane protein, probably involved in polysaccharide biosynthesis (CAE11262.1| YngA protein [Bacillus amyloliquefaciens]; AAG49410.1| dTDP-glucose-4-keto-6-deoxy-D-glucose reductase [Actinobacillus actinomycetemcomitans]; ZP_00293833.1| COG2246: Predicted membrane protein [Thermobifida fusca]). pfam04138, GtrA,GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides.; Conserved hypothetical protein; hypothetical protein 2612566..2613045 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175225 YP_001223054.1 CDS CMM_2309 NC_009480.1 2612952 2613452 R conserved membrane protein (YP_061597.1| Hypothetical protein Lxx05130 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_788994.1| putative integral membrane protein [Tropheryma whipplei TW08/27]).; Conserved hypothetical protein; hypothetical protein complement(2612952..2613452) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174997 YP_001223055.1 CDS CMM_2310 NC_009480.1 2613449 2614183 R putative glycosyl transferase (YP_061598.1| dolichyl-phosphate mannose synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787166.1| glycosyltransferase [Tropheryma whipplei str. Twist]; NP_835088.1| Glycosyltransferase involved in cell wall biogenesis [Bacillus cereus ATCC 14579]). pfam00535, Glycos_transf_2,Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. InterPro: Glycosyl transferase family 2. pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyl transferase complement(2613449..2614183) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175845 YP_001223056.1 CDS moaE NC_009480.1 2615624 2616055 R putative molybdopterin cofactor biosynthesis protein (CAD47961.1| molybdopterin synthase (large subunit moaE) [Arthrobacter nicotinovorans]; CAF18780.1| MOLYBDOPTERIN SYNTHASE, LARGE SUBUNIT [Corynebacterium glutamicum ATCC 13032]). pfam02391, MoaE, MoaE protein. This family contains the MoaE protein that is involved in biosynthesis of molybdopterin. InterPro: Molydopterin converting factor subunit 2.; High confidence in function and specificity; molybdopterin cofactor biosynthesis protein complement(2615624..2616055) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174842 YP_001223057.1 CDS moaB NC_009480.1 2616052 2616606 R putative molybdenum cofactor biosynthesis protein (NP_335315.1| molybdopterin biosynthesis Mog protein [Mycobacterium tuberculosis CDC1551]; NP_824847.1| putative molybdopterin biosynthesis protein [Streptomyces avermitilis MA-4680]). pfam00994, MoCF_biosynth, Probable molybdopterin binding domain. This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor.; Function unclear; putative molybdenum cofactor biosynthesis protein complement(2616052..2616606) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173919 YP_001223058.1 CDS moaC NC_009480.1 2616603 2617097 R putative molybdenum cofactor biosynthesis protein (CAD47960.1| molybdopterin cofactor synthesis protein moaC [Arthrobacter nicotinovorans]; NP_599464.1| molybdenum cofactor biosynthesis enzyme [Corynebacterium glutamicum ATCC 13032]). pfam01967, MoaC, MoaC family. Members of this family are involved in molybdenum cofactor biosynthesis. However their molecular function is not known. InterPro: MoaC family.; High confidence in function and specificity; putative molybdenum cofactor biosynthesis protein complement(2616603..2617097) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174322 YP_001223059.1 CDS moaA1 NC_009480.1 2617090 2618382 R putative molybdopterin biosynthesis protein (CAD47959.1| molybdopterin cofactor synthesis protein moeA [Arthrobacter nicotinovorans]; O53725|MEA2_MYCTU Molybdopterin biosynthesis protein moeA 2). pfam03453,MoeA_N, MoeA N-terminal region (domain I and II). pfam00994, MoCF_biosynth, Probable molybdopterin binding domain. pfam03454, MoeA_C, MoeA C-terminal region (domain IV). InterPro: Molybdenum cofactor biosynthesis protein.; High confidence in function and specificity; putative molybdopterin biosynthesis protein complement(2617090..2618382) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175520 YP_001223060.1 CDS CMM_2315 NC_009480.1 2618515 2618739 D hypothetical protein 2618515..2618739 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175689 YP_001223061.1 CDS CMM_2316 NC_009480.1 2618837 2619610 D conserved hypothetical protein, putative carboxyphosphonoenolpyruvate phosphonomutase (AAU16741.1| conserved hypothetical protein; possible carboxyphosphonoenolpyruvate phosphonomutase [Bacillus cereus ZK]; NP_463608.1|; Function unclear; putative carboxyphosphonoenolpyruvate phosphonomutase 2618837..2619610 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173949 YP_001223062.1 CDS CMM_2317 NC_009480.1 2619720 2620640 D putative methylthioadenosine phosphorylase (ZP_00059934.1| COG0005: Purine nucleoside phosphorylase [Clostridium thermocellum ATCC 27405]; NP_627402.1| putative methylthioadenosine phosphorylase [Streptomyces coelicolor A3(2)]). pfam00896, Mtap_PNP, Phosphorylase family 2.; Specificity unclear; putative methylthioadenosine phosphorylase 2619720..2620640 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174993 YP_001223063.1 CDS galE3 NC_009480.1 2620637 2621701 D putative UDP-glucose 4-epimerase (NP_627930.1| putative epimerase [Streptomyces coelicolor A3(2)]; NP_334969.1| NAD-dependent epimerase/dehydratase family protein [Mycobacterium tuberculosis CDC1551]). pfam01370,Epimerase, NAD dependent epimerase/dehydratase family. InterPro: NAD dependent epimerase/dehydratase family.; Specificity unclear; putative UDP-glucose 4-epimerase 2620637..2621701 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174589 YP_001223064.1 CDS CMM_2319 NC_009480.1 2621822 2622271 D hypothetical protein 2621822..2622271 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174697 YP_001223065.1 CDS CMM_2320 NC_009480.1 2622330 2623118 R putative short chain dehydrogenase/oxidoreductase (LVR_LEIAQ Levodione reductase ((6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase) [Leifsonia aquatica]; NP_691955.1| cyclohexanol dehydrogenase [Oceanobacillus iheyensis HTE831]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase complement(2622330..2623118) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174558 YP_001223066.1 CDS CMM_2321 NC_009480.1 2623196 2624224 R hypothetical membrane protein, putative protease (NP_691838.1| hypothetical protein OB0917 [Oceanobacillus iheyensis HTE831]; YP_099030.1| putative metal-dependent membrane protease [Bacteroides fragilis YCH46]).; hypothetical protein complement(2623196..2624224) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174515 YP_001223067.1 CDS CMM_2322 NC_009480.1 2624335 2624799 R hypothetical protein (ZP_00193445.2| hypothetical protein MBNC02003411 [Mesorhizobium sp. BNC1]; AAG02159.1| unknown [Zymomonas mobilis]).; hypothetical protein complement(2624335..2624799) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174888 YP_001223068.1 CDS CMM_2323 NC_009480.1 2624856 2625038 R hypothetical protein complement(2624856..2625038) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174111 YP_001223069.1 CDS CMM_2324 NC_009480.1 2625536 2626249 D hypothetical protein 2625536..2626249 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174377 YP_001223070.1 CDS CMM_2325 NC_009480.1 2626246 2627307 D hypothetical protein 2626246..2627307 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175603 YP_001223071.1 CDS CMM_2326 NC_009480.1 2627593 2628633 D putative permease (NP_721165.1| conserved hypothetical protein; putative permease [Streptococcus mutans UA159]; NP_978154.1| membrane protein, putative [Bacillus cereus ATCC 10987]; NP_825745.1| hypothetical protein SAV4568 [Streptomyces avermitilis MA-4680]). pfam03773, DUF318, Predicted permease. This family of integral membrane proteins are predicted to be permeases of unknown specificity.; putative permease 2627593..2628633 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175147 YP_001223072.1 CDS CMM_2327 NC_009480.1 2628620 2629543 D conserved membrane protein (NP_681143.1| hypothetical protein tlr0353 [Thermosynechococcus elongatus BP-1]; ZP_00112177.1| COG3689: Predicted membrane protein [Nostoc punctiforme PCC 73102]). 2_A_01_02: Multidrug resistance protein; Conserved hypothetical protein; hypothetical protein 2628620..2629543 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172996 YP_001223073.1 CDS CMM_2328 NC_009480.1 2629551 2630942 D hypothetical protein 2629551..2630942 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173771 YP_001223074.1 CDS CMM_2329 NC_009480.1 2630973 2631356 D conserved hypothetical protein (ZP_00220356.1| COG0662: Mannose-6-phosphate isomerase [Burkholderia cepacia R1808]; ZP_00135743.1| COG0662: Mannose-6-phosphate isomerase [Pseudomonas aeruginosa UCBPP-PA14]).; Function unclear; hypothetical protein 2630973..2631356 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173901 YP_001223075.1 CDS CMM_2330 NC_009480.1 2631480 2632172 R hypothetical protein (NP_925435.1| hypothetical protein glr2489 [Gloeobacter violaceus PCC 7421]; ZP_00291340.1| COG2931: RTX toxins and related Ca2+-binding proteins).; hypothetical protein complement(2631480..2632172) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174188 YP_001223076.1 CDS CMM_2331 NC_009480.1 2632438 2633121 D putative transcriptional regulator, PadR family (NP_625650.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_959288.1| hypothetical protein MAP0354c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam03551, PadR, Transcriptional regulator PadR-like family.; Specificity unclear; hypothetical protein 2632438..2633121 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175166 YP_001223077.1 CDS CMM_2332 NC_009480.1 2633198 2633452 R hypothetical protein complement(2633198..2633452) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173017 YP_001223078.1 CDS CMM_2333 NC_009480.1 2633569 2635188 R putative membrane-bound oxidoreductase (NP_624868.1| putative membrane-bound oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00228326.1| COG2041: Sulfite oxidase and related enzymes [Kineococcus radiotolerans SRS30216]). pfam00174, Oxidored_molyb,Oxidoreductase molybdopterin binding domain. This domain is found in a variety of oxidoreductases. pfam03404, Mo-co_dimer, Mo-co oxidoreductase dimerisation domain. This domain is found in molybdopterin cofactor (Mo-co) oxidoreductases. It is involved in dimer formation, and has an Ig-fold structure.; Function unclear; putative membrane-bound oxidoreductase complement(2633569..2635188) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173536 YP_001223079.1 CDS CMM_2334 NC_009480.1 2635185 2636447 R putative two-component system sensor kinase (NP_825594.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; NP_824147.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]). pfam00512, HisKA, His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase complement(2635185..2636447) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173655 YP_001223080.1 CDS CMM_2335 NC_009480.1 2636444 2637295 R putative two-component system response regulator (NP_825593.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]; ZP_00062053.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Clostridium thermocellum ATCC 27405]). pfam00072,Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. pfam00486,Trans_reg_C, Transcriptional regulatory protein, C terminal.; Specificity unclear; putative two-component system response regulator complement(2636444..2637295) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173905 YP_001223081.1 CDS CMM_2336 NC_009480.1 2637444 2638151 D putative glycosyl transferase (NP_627933.1| putative glycosyltransferase [Streptomyces coelicolor A3(2)]; O32851|Y539_MYCTU Putative glycosyl transferase Rv0539/MT0564/Mb0553). pfam00535, Glycos_transf_2,Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyltransferase 2637444..2638151 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173814 YP_001223082.1 CDS CMM_2337 NC_009480.1 2638148 2638831 D conserved hypothetical protein (NP_825749.1| hypothetical protein SAV4572 [Streptomyces avermitilis MA-4680]; NP_215054.1| hypothetical protein Rv0540 [Mycobacterium tuberculosis H37Rv]). pfam05143, DUF703,Uncharacterized BCR (DUF703). Proteins in this family have no known function. They contain many conserved aspartates that might suggest this is a metalloprotein.; Function unclear; hypothetical protein 2638148..2638831 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175757 YP_001223083.1 CDS CMM_2338 NC_009480.1 2638828 2639529 D putative SAM-dependant methyltransferase (NP_825748.1| hypothetical protein [Streptomyces avermitilis MA-4680]; AAK68925.1| putative methyltransferase [Bacteroides fragilis]). InterPro: SAM (and some other nucleotide) binding motif.; Family membership; putative SAM-dependent methyltransferase 2638828..2639529 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175196 YP_001223084.1 CDS CMM_2339 NC_009480.1 2639478 2639957 R Hypothetical protein; hypothetical protein complement(2639478..2639957) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174773 YP_001223085.1 CDS CMM_2340 NC_009480.1 2639957 2641198 R conserved membrane protein (CAB07013.1| PROBABLE CONSERVED TRANSMEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_627937.1| putative membrane protein [Streptomyces coelicolor A3(2)]). pfam00174,Oxidored_molyb, Oxidoreductase molybdopterin binding domain. CynX: Cyanate transport system protein; Family membership; hypothetical protein complement(2639957..2641198) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173492 YP_001223086.1 CDS CMM_2341 NC_009480.1 2641277 2642725 D hypothetical membrane protein (only weak similarities: NP_960846.1| hypothetical protein MAP1912 [Mycobacterium avium subsp. paratuberculosis str. k10]; YP_056579.1| conserved membrane protein [Propionibacterium acnes KPA171202]).; hypothetical protein 2641277..2642725 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173790 YP_001223087.1 CDS modC NC_009480.1 2642726 2643784 R putative molybdate ABC transporter, ATP-binding protein (NP_822897.1| putative ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]; ZP_00292621.1| COG1118: ABC-type sulfate/molybdate transport systems, ATPase component [Thermobifida fusca]). pfam00005, ABC_tran, ABC transporter.; High confidence in function and specificity; putative molybdate ABC transporter ATP-binding protein complement(2642726..2643784) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175391 YP_001223088.1 CDS modB NC_009480.1 2643781 2644638 R putative molybdate ABC transporter, permease component (NP_627897.1| putative ABC transporter membrane subunit [Streptomyces coelicolor A3(2)]; ZP_00292622.1| COG4149: ABC-type molybdate transport system, permease component [Thermobifida fusca]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component.; High confidence in function and specificity; putative molybdate ABC transporter permease complement(2643781..2644638) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173899 YP_001223089.1 CDS modA NC_009480.1 2644628 2645434 R putative molybdate ABC transporter, substrate-binding protein (NP_822895.1| putative substrate-binding periplasmic transport [Streptomyces avermitilis MA-4680]; YP_120541.1| putative transporter [Nocardia farcinica]).; High confidence in function and specificity; putative molybdate ABC transporter substrate-binding protein complement(2644628..2645434) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174846 YP_001223090.1 CDS CMM_2345 NC_009480.1 2645434 2645946 R putative transcriptional regulator involved in molybdate uptake (NP_960055.1| hypothetical protein MAP1121c [Mycobacterium avium subsp. paratuberculosis str. k10]; YP_055214.1| putative molybdopterin-binding protein [Propionibacterium acnes KPA171202]). COG3585, MopI,Molybdopterin-binding protein [Coenzyme metabolism].; High confidence in function and specificity; putative transcriptional regulator involved in molybdate uptake complement(2645434..2645946) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175807 YP_001223091.1 CDS moaA NC_009480.1 2646067 2647125 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 2646067..2647125 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174673 YP_001223092.1 CDS moaD NC_009480.1 2647139 2647393 D putative molybdopterin converting factor, small subunit (CAD47957.1| putative molybdopterin cofactor synthesis protein moaD [Arthrobacter nicotinovorans]; NP_959740.1| MoaD2 [Mycobacterium avium subsp. paratuberculosis str. k10]).; High confidence in function and specificity; putative molybdopterin converting factor 2647139..2647393 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175923 YP_001223093.1 CDS CMM_2348 NC_009480.1 2647417 2648304 D putative siderophore-interacting protein (NP_600036.1| siderophore- interacting protein [Corynebacterium glutamicum ATCC 13032]; ZP_00139712.1| COG2375: Siderophore-interacting protein [Pseudomonas aeruginosa UCBPP-PA14]). pfam04954, SIP, Siderophore-interacting protein.; Function unclear; putative siderophore-interacting protein 2647417..2648304 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173724 YP_001223094.1 CDS fecB1 NC_009480.1 2648374 2649348 D putative Fe3+-siderophore ABC transporter,substrate-binding protein (NP_600037.1| ABC-type cobalamin/Fe3+-siderophore transport system, periplasmic component [Corynebacterium glutamicum ATCC 13032]; ZP_00187377.2| COG0614: ABC-type Fe3+-hydroxamate transport system, periplasmic component [Rubrobacter xylanophilus DSM 9941]). , pfam01497, Peripla_BP_2,Periplasmic binding protein. This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport.; Specificity unclear; putative Fe3+-siderophore ABC transportersubstrate-binding protein 2648374..2649348 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174685 YP_001223095.1 CDS fecC1 NC_009480.1 2649345 2650358 D putative Fe3+-siderophore ABC transporter, permease component (CAF19214.1| cobalamin/ Fe3+-siderophores transport system, permease component [Corynebacterium glutamicum ATCC 13032]; AAD29085.1| FepD [Yersinia enterocolitica]). , pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system. InterPro: FecCD transport family.; Specificity unclear; putative Fe3+-siderophore ABC transporterpermease 2649345..2650358 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172986 YP_001223096.1 CDS fecD1 NC_009480.1 2650355 2651407 D putative Fe3+-siderophore ABC transporter, permease component (NP_535687.1| ABC transporter, membrane spanning protein [iron] [Agrobacterium tumefaciens str. C58]; CAF19213.1| cobalamin/Fe3+-siderophores transport system,permease component [Corynebacterium glutamicum ATCC 13032]). , pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.,InterPro: FecCD transport family; Specificity unclear; putative Fe3+-siderophore ABC transporterpermease 2650355..2651407 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173027 YP_001223097.1 CDS CMM_2352 NC_009480.1 2651453 2651932 R conserved hypothetical protein (ZP_00028735.1| COG3865: Uncharacterized protein conserved in bacteria [Burkholderia fungorum]; NP_961602.1| hypothetical protein MAP2668c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam06983, 3-dmu-9_3-mt, 3-demethylubiquinone-9 3-methyltransferase.; Function unclear; hypothetical protein complement(2651453..2651932) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173137 YP_001223098.1 CDS CMM_2353 NC_009480.1 2652042 2653007 R putative membrane protein (NP_628002.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; Hypothetical protein; hypothetical protein complement(2652042..2653007) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174753 YP_001223099.1 CDS CMM_2354 NC_009480.1 2653004 2653354 R putative transcriptional regulator, GntR family (NP_628001.1| putative putative transcriptional regulator,GntR family [Streptomyces coelicolor A3(2)]; NP_765180.1| transcription regulator GntR family [Staphylococcus epidermidis ATCC 12228]). pfam00392, GntR, Bacterial regulatory proteins, gntR family. InterPro: Bacterial regulatory proteins GntR family.; Specificity unclear; GntR family transcriptional regulator complement(2653004..2653354) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175235 YP_001223100.1 CDS CMM_2355 NC_009480.1 2653401 2654468 R putative transcriptional regulator, LacI family (ZP_00238821.1| ribose operon repressor RbsR [Bacillus cereus G9241]; NP_621898.1| Transcriptional regulator [Thermoanaerobacter tengcongensis]; NP_625360.1| putative lacI-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. InterPro: Periplasmic binding proteins and sugar binding domain LacI family.; Specificity unclear; LacI family transcriptional regulator complement(2653401..2654468) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174314 YP_001223101.1 CDS CMM_2356 NC_009480.1 2654447 2656480 R putative oxidoreductase (NP_106951.1| ; NP_533647.1| oxidoreductase [Agrobacterium tumefaciens str. C58]). contains two domains: N-terminal, COG0673,MviM, Predicted dehydrogenases and related proteins; pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. C-terminal, COG0667, Tas, Predicted oxidoreductases; pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative oxidoreductase complement(2654447..2656480) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175579 YP_001223102.1 CDS CMM_2357 NC_009480.1 2656608 2656919 R putative transcriptional regulator,ArsR family (NP_422181.1| conserved hypothetical protein [Caulobacter crescentus CB15]; ZP_00199062.1| COG1846: Transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam01022, HTH_5, Bacterial regulatory protein, arsR family.; Specificity unclear; ArsR family transcriptional regulator complement(2656608..2656919) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174159 YP_001223103.1 CDS CMM_2358 NC_009480.1 2656919 2657335 R Hypothetical protein; hypothetical protein complement(2656919..2657335) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174432 YP_001223104.1 CDS CMM_2359 NC_009480.1 2657452 2657946 R putative transcriptional regulator, MarR family (NP_629432.1| putative MarR-family transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00197677.1| COG1846: Transcriptional regulators [Mesorhizobium sp. BNC1]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; hypothetical protein complement(2657452..2657946) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174262 YP_001223105.1 CDS CMM_2360 NC_009480.1 2658055 2658552 D conserved membrane protein (NP_739226.1| hypothetical protein CE2616 [Corynebacterium efficiens YS-314]; YP_061908.1| Hypothetical protein Lxx09140 [Leifsonia xyli subsp. xyli str. CTCB07]). 2_A_01_02: Multidrug resistance protein; Conserved hypothetical protein; hypothetical protein 2658055..2658552 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175594 YP_001223106.1 CDS CMM_2361 NC_009480.1 2658605 2659216 R hypothetical acetyltransferase (ZP_00210091.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Magnetospirillum magnetotacticum MS-1]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Hypothetical protein; acetyltransferase complement(2658605..2659216) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174415 YP_001223107.1 CDS CMM_2362 NC_009480.1 2659384 2660649 D hypothetical protein 2659384..2660649 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175545 YP_001223108.1 CDS moeB NC_009480.1 2660677 2661864 R putative molybdenum cofactor biosynthesis protein (Molybdopterin synthase sulfurylase) (YP_120782.1| putative molybdopterin biosynthesis protein [Nocardia farcinica]; NP_301623.1| probably involved in molybdopterin biosynthesis [Mycobacterium leprae TN]). pfam00899, ThiF, ThiF family. This family contains a repeated domain in ubiquitin activating enzyme E1 and members of the bacterial ThiF/MoeB/HesA family. pfam05237,MoeZ_MoeB, MoeZ/MoeB domain. pfam00581, Rhodanese,Rhodanese-like domain.; High confidence in function and specificity; putative molybdenum cofactor biosynthesis protein complement(2660677..2661864) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175076 YP_001223109.1 CDS CMM_2364 NC_009480.1 2661863 2663569 D conserved membrane protein (NP_962739.1| hypothetical protein MAP3805c [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_826266.1| hypothetical protein SAV5089 [Streptomyces avermitilis MA-4680]). 2A0106: citrate-proton symport; Conserved hypothetical protein; hypothetical protein 2661863..2663569 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174826 YP_001223110.1 CDS CMM_2365 NC_009480.1 2663582 2664442 R putative hydrolase (NP_823898.1| putative hydrolase [Streptomyces avermitilis MA-4680]; ZP_00216890.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Burkholderia cepacia R18194]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Family membership; putative hydrolase complement(2663582..2664442) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174185 YP_001223111.1 CDS CMM_2366 NC_009480.1 2664529 2665032 D conserved hypothetical protein (NP_624780.1| hypothetical protein SCF51A.38 [Streptomyces coelicolor A3(2)]; YP_120059.1| hypothetical protein nfa38470 [Nocardia farcinica]). pfam07336, DUF1470, Protein of unknown function (DUF1470). ahpD_dom: alkylhydroperoxidase AhpD famil; hypothetical protein 2664529..2665032 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174593 YP_001223112.1 CDS ispE NC_009480.1 2666044 2666982 R catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(2666044..2666982) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175414 YP_001223113.1 CDS ksgA NC_009480.1 2666993 2667907 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(2666993..2667907) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174936 YP_001223114.1 CDS CMM_2369 NC_009480.1 2667904 2668854 R putative DNase (YP_062611.1| sec-independent protein TadD [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227356.1| COG0084: Mg-dependent DNase [Kineococcus radiotolerans SRS30216]; NP_789377.1| putative TatD-family DNase [Tropheryma whipplei TW08/27]). pfam01026,TatD_DNase, TatD related DNase. This family of proteins are related to a large superfamily of metalloenzymes. TatD, a member of this family has been shown experimentally to be a DNase enzyme.; Function unclear; hypothetical protein complement(2667904..2668854) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175663 YP_001223115.1 CDS metS NC_009480.1 2668926 2670503 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(2668926..2670503) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175693 YP_001223116.1 CDS gltA1 NC_009480.1 2670566 2671717 R catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase complement(2670566..2671717) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174656 YP_001223117.1 CDS CMM_2372 NC_009480.1 2671965 2673452 D putative dihydrolipoamide dehydrogenase (E3) component (ZP_00163991.2| COG1249: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Synechococcus elongatus PCC 7942]; NP_713067.1| Dihydrolipoamide dehydrogenase [Leptospira interrogans serovar Lai str. 56601]). ,pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. , pfam02852, Pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.; Function unclear; putative dihydrolipoamide dehydrogenase (E3) component 2671965..2673452 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175234 YP_001223118.1 CDS CMM_2373 NC_009480.1 2673487 2674095 D putative NAD(P)H oxidoreductase (NP_249916.1| probable NAD(P)H dehydrogenase [Pseudomonas aeruginosa PA01]; ZP_00270658.1| COG2249: Putative NADPH-quinone reductase (modulator of drug activity B) [Rhodospirillum rubrum])., , pfam02525, Flavodoxin_2, Flavodoxin-like fold.; Function unclear; putative NAD(P)H oxidoreductase 2673487..2674095 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175948 YP_001223119.1 CDS CMM_2374 NC_009480.1 2674118 2675161 R putative Zn-dependant alcohol dehydrogenase (NP_628443.1| putative NADP-dependent alcohol dehydrogenase [Streptomyces coelicolor A3(2)]; NP_299023.1| NADP-alcohol dehydrogenase [Xylella fastidiosa 9a5c]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase. tdh: L-threonine 3-dehydrogenase; Function unclear; putative Zn-dependent alcohol dehydrogenase complement(2674118..2675161) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175444 YP_001223120.1 CDS CMM_2375 NC_009480.1 2675207 2675797 D putative transcriptional regulator, TetR family (ZP_00191751.2| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_628442.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family.; Specificity unclear; TetR family transcriptional regulator 2675207..2675797 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175433 YP_001223121.1 CDS CMM_2376 NC_009480.1 2675821 2676240 R putative membrane protein (AAN58622.1| conserved hypothetical protein [Streptococcus mutans UA159]; AAF24085.1| unknown [Staphylococcus aureus]).; hypothetical protein complement(2675821..2676240) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174989 YP_001223122.1 CDS CMM_2377 NC_009480.1 2676441 2677838 D putative SAM-dependent methyltransferase (NP_630088.1| hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00060190.1| COG0500: SAM-dependent methyltransferases [Clostridium thermocellum ATCC 27405]).; Function unclear; putative SAM-dependent methyltransferase 2676441..2677838 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172973 YP_001223123.1 CDS CMM_2378 NC_009480.1 2677835 2680420 D putative phosphatase (ZP_00227056.1| COG0639: Diadenosine tetraphosphatase and related serine/threonine protein phosphatases [Kineococcus radiotolerans SRS30216]; NP_630089.1| putative phosphatase [Streptomyces coelicolor A3(2)]). pfam00149, Metallophos,Calcineurin-like phosphoesterase. InterPro: Serine/threonine specific protein phosphatase.; Function unclear; putative phosphatase 2677835..2680420 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173521 YP_001223124.1 CDS prpB NC_009480.1 2680639 2681553 R putative methylisocitrate lyase (YP_061313.1| phosphonomutase [Leifsonia xyli subsp. xyli str. CTCB07]; Q8NSL2|PRB2_CORGL Probable methylisocitrate lyase 2 (2-methylisocitrate lyase 2)).; Specificity unclear; putative methylisocitrate lyase/phosphonomutase complement(2680639..2681553) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174785 YP_001223125.1 CDS prpD NC_009480.1 2681553 2683103 R putative 2-methylcitrate dehydratase (ZP_00267780.1| COG2079: Uncharacterized protein involved in propionate catabolism [Rhodospirillum rubrum]; Q8NSL3|PRD2_CORGL 2-methylcitrate dehydratase 2). pfam03972, MmgE_PrpD, MmgE/PrpD family. This family includes 2-methylcitrate dehydratase EC:4.2.1.79 that is required for propionate catabolism. It catalyses the third step of the 2-methylcitric acid cycle.; Specificity unclear; putative 2-methylcitrate dehydratase complement(2681553..2683103) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174213 YP_001223126.1 CDS CMM_2381 NC_009480.1 2683142 2684110 D putative acetyltransferase pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions (duplicated). similarities N-terminal: putative IAA acetyltransferase; D97569 iaa acetyltransferase [imported] - Agrobacterium tumefaciens (strain C58,Cereon); P26945|IAAT_AZOBR IAA ACETYLTRANSFERASE). C-terminal: NP_627571.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]; ZP_00215080.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Burkholderia cepacia R18194]. duplicated domain: pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative duplicated acetyltransferase 2683142..2684110 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174953 YP_001223127.1 CDS CMM_2382 NC_009480.1 2685035 2686447 D hypothetical protein, putative perforin (CAE13708.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1]; ZP_00328149.1| hypothetical protein Tery02000057 [Trichodesmium erythraeum IMS101]). , weak similarity to: smart00457,MACPF, membrane-attack complex/perforin; putative perforin 2685035..2686447 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175248 YP_001223128.1 CDS CMM_2383 NC_009480.1 2686864 2687451 R conserved hypothetical protein (NP_642470.1| hypothetical protein XAC2153 [Xanthomonas axonopodis pv. citri str. 306]; ZP_00127398.2| COG3506: Uncharacterized conserved protein [Pseudomonas syringae pv. syringae B728a]). pfam07081, DUF1349, Protein of unknown function (DUF1349).; hypothetical protein complement(2686864..2687451) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173203 YP_001223129.1 CDS CMM_2384 NC_009480.1 2687476 2688069 D putative sugar acetyltransferase (NP_631564.1| putative sugar acetyltransferase [Streptomyces coelicolor A3(2)]; ZP_00291641.1| COG0110: Acetyltransferase (isoleucine patch superfamily) [Thermobifida fusca]). cd00208, LbetaH, Left-Handed Parallel beta-Helix; Proteins containing hexapeptide repeats are often enzymes showing acyl-transferase activity, many are trimeric in their active form. InterPro: Bacterial transferase hexapeptide repeat.; Function unclear; putative sugar acetyltransferase 2687476..2688069 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173430 YP_001223130.1 CDS CMM_2385 NC_009480.1 2688066 2688659 D putative transcriptional regulator, TetR family (NP_631563.1| putative tetR-family transcriptional regulatory protein [Streptomyces coelicolor A3(2)]; NP_415367.1| putative DEOR-type transcriptional regulator; putative transcriptional regulator (TetR family) [Escherichia coli K12]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family.; Specificity unclear; TetR family transcriptional regulator 2688066..2688659 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175709 YP_001223131.1 CDS CMM_2386 NC_009480.1 2688928 2690457 D putative membrane-bound tyrosin-protein phosphatase (YP_014420.1| protein-tyrosine phosphatase, putative [Listeria monocytogenes str. 4b F2365]). pfam03162,Y_phosphatase2, Tyrosine phosphatase family. InterPro: Tyrosine specific protein phosphatase and dual specificity protein phosphatase family.; Family membership; putative membrane-bound tyrosin-protein phosphatase 2688928..2690457 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175357 YP_001223132.1 CDS CMM_2387 NC_009480.1 2690466 2691113 D Hypothetical protein; hypothetical protein 2690466..2691113 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175041 YP_001223133.1 CDS CMM_2388 NC_009480.1 2691192 2692289 D conserved membrane protein (NP_736677.1| hypothetical protein CE0067 [Corynebacterium efficiens YS-314]; NP_625097.1| putative integral membrane protein. [Streptomyces coelicolor A3(2)]).; Conserved hypothetical protein; hypothetical protein 2691192..2692289 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175108 YP_001223134.1 CDS CMM_2389 NC_009480.1 2692308 2693273 R putative permease, DMT family (ZP_00294424.1| COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily [Thermobifida fusca]; YP_117052.1| hypothetical protein nfa8430 [Nocardia farcinica]). pfam00892, DUF6, Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function (duplicated).; Specificity unclear; permease DMT family complement(2692308..2693273) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174945 YP_001223135.1 CDS CMM_2390 NC_009480.1 2693347 2693907 D conserved hypothetical protein (NP_827985.1| hypothetical protein SAV6809 [Streptomyces avermitilis MA-4680]; NP_927352.1| hypothetical protein glr4405 [Gloeobacter violaceus PCC 7421]). pfam07336, DUF1470,Protein of unknown function (DUF1470).; hypothetical protein 2693347..2693907 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174453 YP_001223136.1 CDS CMM_2391 NC_009480.1 2693927 2694742 R putative methyltransferase (YP_062614.1| tetrapyrrole methylase [Leifsonia xyli subsp. xyli str. CTCB07]; BAB98284.1| Predicted methyltransferases [Corynebacterium glutamicum ATCC 13032]). pfam00590,TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases. This family uses S-AdoMet in the methylation of diverse substrates. InterPro: Uncharacterized protein family UPF0011.; Function unclear; putative methyltransferase complement(2693927..2694742) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173313 YP_001223137.1 CDS CMM_2392 NC_009480.1 2694739 2695059 R hypothetical protein complement(2694739..2695059) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173247 YP_001223138.1 CDS CMM_2393 NC_009480.1 2695639 2696082 D conserved membrane protein (NP_939230.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]; NP_744462.1| hypothetical protein PP2313 [Pseudomonas putida KT2440]). pfam04173, DoxD, DoxD-like family.; Conserved hypothetical protein; hypothetical protein 2695639..2696082 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173215 YP_001223139.1 CDS CMM_2394 NC_009480.1 2696095 2696316 R Hypothetical protein; hypothetical protein complement(2696095..2696316) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174772 YP_001223140.1 CDS aglB NC_009480.1 2696499 2698745 D putative alpha glycosidase 2696499..2698745 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173518 YP_001223141.1 CDS CMM_2396 NC_009480.1 2698798 2699334 R hypothetical protein complement(2698798..2699334) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175551 YP_001223142.1 CDS CMM_2397 NC_009480.1 2699336 2699902 R hypothetical protein complement(2699336..2699902) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174550 YP_001223143.1 CDS CMM_2398 NC_009480.1 2700125 2701852 D putative dolichyl-phosphate-mannose-protein mannosyltransferase (YP_062615.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228125.1| COG1928: Dolichyl-phosphate-mannose-protein O-mannosyl transferase [Kineococcus radiotolerans SRS30216]; NP_627370.1| putative integral membrane protein. [Streptomyces coelicolor A3(2)]). pfam02366, PMT,Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyl- transferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyse the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. InterPro: Dolichyl-phosphate-mannose-protein mannosyltransferase.; Function unclear; dolichyl-phosphate-mannose-protein mannosyltransferase 2700125..2701852 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174378 YP_001223144.1 CDS CMM_2399 NC_009480.1 2701852 2702856 D conserved membrane protein (CAF18580.1| HYPOTHETICAL MEMBRANE PROTEIN [Corynebacterium glutamicum ATCC 13032]; ZP_00226109.1| COG2855: Predicted membrane protein [Kineococcus radiotolerans SRS30216]). pfam03601,Cons_hypoth698, Conserved hypothetical protein 698.; hypothetical protein 2701852..2702856 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173464 YP_001223145.1 CDS CMM_2400 NC_009480.1 2702957 2704252 D putative O-acetylhomoserine (thiol)-lyase (ZP_00352381.1| COG2873: O-acetylhomoserine sulfhydrylase [Kineococcus radiotolerans SRS30216]; ZP_00329508.1| COG2873: O-acetylhomoserine sulfhydrylase [Moorella thermoacetica ATCC 39073]). pfam01053, Cys_Met_Meta_PP,Cys/Met metabolism PLP-dependent enzyme. This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.; High confidence in function and specificity; putative O-acetylhomoserine (thiol)-lyase 2702957..2704252 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175392 YP_001223146.1 CDS CMM_2401 NC_009480.1 2704249 2705022 D conserved hypothetical protein (ZP_00225776.1| COG1832: Predicted CoA-binding protein [Kineococcus radiotolerans SRS30216]; NP_243007.1| BH2141~unknown conserved protein [Bacillus halodurans C-125]). pfam02629,CoA_binding, CoA binding domain. This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases. InterPro: DUF184.; Family membership; hypothetical protein 2704249..2705022 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172962 YP_001223147.1 CDS CMM_2402 NC_009480.1 2705041 2705550 R conserved hypothetical protein (NP_683235.1| hypothetical protein tll2445 [Thermosynechococcus elongatus BP-1]; ZP_00353314.1| COG2343: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). pfam04248, DUF427, Domain of unknown function (DUF427). L37a: ribosomal protein L37a; hypothetical protein complement(2705041..2705550) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175622 YP_001223148.1 CDS CMM_2403 NC_009480.1 2705737 2705997 D conserved membrane protein (YP_056449.1| hypothetical protein PPA1762 [Propionibacterium acnes KPA171202]; ZP_00208942.1| COG2261: Predicted membrane protein [Magnetospirillum magnetotacticum MS-1]).; Conserved hypothetical protein; hypothetical protein 2705737..2705997 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172922 YP_001223149.1 CDS CMM_2404 NC_009480.1 2706088 2706834 D Hypothetical protein; hypothetical protein 2706088..2706834 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174897 YP_001223150.1 CDS sdaA NC_009480.1 2706844 2708211 D putative L-serine dehydratase (ZP_00278039.1| COG1760: L-serine deaminase [Burkholderia fungorum LB400]; ZP_00244926.1| COG1760: L-serine deaminase [Rubrivivax gelatinosus PM1]). pfam03313, SDH_alpha,Serine dehydratase alpha chain.L-serine dehydratase (EC:4.2.1.13) is a found as a heterodimer of alpha and beta chain or as a fusion of the two chains in a single protein. This enzyme catalyses the deamination of serine to form pyruvate. This enzyme is part of the gluconeogenesis pathway. pfam03315, SDH_beta, Serine dehydratase beta chain. InterPro: Iron-sulfur-dependent L-serine dehydratase single chain form.; High confidence in function and specificity; putative L-serine dehydratase 2706844..2708211 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174543 YP_001223151.1 CDS CMM_2406 NC_009480.1 2708249 2708644 D hypothetical membrane protein (NP_600018.1| hypothetical membrane protein [Corynebacterium glutamicum ATCC 13032];).; Hypothetical protein; hypothetical protein 2708249..2708644 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175647 YP_001223152.1 CDS CMM_2407 NC_009480.1 2708641 2709747 R conserved hypothetical protein (AAL17938.1| alanine-rich hypothetical protein [Mycobacterium smegmatis]; NP_626160.1| hypothetical alanine-rich protein [Streptomyces coelicolor A3(2)]).; hypothetical protein complement(2708641..2709747) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173090 YP_001223153.1 CDS CMM_2408 NC_009480.1 2709744 2710535 R putative transcriptional regulator, IclR family (NP_827564.1| putative IclR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_626139.1| putative IclR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). , pfam01614,IclR, Bacterial transcriptional regulator. , InterPro: Bacterial regulatory proteins IclR family.; Specificity unclear; IclR family transcriptional regulator complement(2709744..2710535) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174000 YP_001223154.1 CDS CMM_2409 NC_009480.1 2710532 2711326 R putative NDP-sugar epimerase (AAL17942.1| putative UDP glucose epimerase [Mycobacterium smegmatis]; ZP_00057790.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Thermobifida fusca]). pfam01370, Epimerase,NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Function unclear; putative NDP-sugar epimerase complement(2710532..2711326) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173934 YP_001223155.1 CDS CMM_2410 NC_009480.1 2711440 2712786 D putative sugar ABC transporter, substrate-binding protein (YP_069044.1| putative sugar binding protein, ABC transport system [Yersinia pseudotuberculosis IP 32953]; NP_826308.1| putative sugar transporter sugar-binding protein [Streptomyces avermitilis MA-4680]). pfam01547,SBP_bac_1, Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1.; Specificity unclear; putative sugar ABC transporter substrate-binding protein 2711440..2712786 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173376 YP_001223156.1 CDS CMM_2411 NC_009480.1 2712783 2713745 D putative sugar ABC transporter, permease component (NP_406930.1| sugar transport system, permease protein [Yersinia pestis CO92]; NP_107401.1| ABC transporter,permease protein [Mesorhizobium loti MAFF303099]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 2712783..2713745 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175957 YP_001223157.1 CDS CMM_2412 NC_009480.1 2713742 2714647 D putative sugar ABC transporter, permease component (NP_406929.1| sugar transport system, permease protein [Yersinia pestis CO92]; YP_059565.1| N-acetylneuraminate transport system permease protein [Streptococcus pyogenes MGAS10394]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 2713742..2714647 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173983 YP_001223158.1 CDS CMM_2413 NC_009480.1 2714652 2715884 D putative glucarate dehydratase (EAA73209.1| conserved hypothetical protein [Gibberella zeae PH-1]; NP_826758.1| putative glucarate dehydratase [Streptomyces avermitilis MA-4680]). pfam02746, MR_MLE_N, Mandelate racemase / muconate lactonizing enzyme, N-terminal domain. pfam01188, MR_MLE, Mandelate racemase / muconate lactonizing enzyme, C-terminal domain. InterPro: Mandelate racemase/muconate lactonizing enzyme family.; Specificity unclear; putative glucarate dehydratase 2714652..2715884 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174823 YP_001223159.1 CDS CMM_2414 NC_009480.1 2715884 2716852 D catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate; 5-dehydro-4-deoxyglucarate dehydratase 2715884..2716852 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173305 YP_001223160.1 CDS CMM_2415 NC_009480.1 2716857 2718758 R conserved hypothetical protein (ZP_00291796.1| COG1331: Highly conserved protein containing a thioredoxin domain [Thermobifida fusca]; NP_824472.1| hypothetical protein SAV3296 [Streptomyces avermitilis MA-4680]). pfam03190, DUF255, Protein of unknown function, DUF255.; hypothetical protein complement(2716857..2718758) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175779 YP_001223161.1 CDS corA2 NC_009480.1 2718810 2719976 R putative magnesium and cobalt transport protein,MIT family (NP_823212.1| putative metal-transport protein [Streptomyces avermitilis MA-4680]; ZP_00292887.1| COG0598: Mg2+ and Co2+ transporters [Thermobifida fusca]). pfam01544, CorA, CorA-like Mg2+ transporter protein. ,InterPro: CorA-like Mg2+ transporter protein.; Specificity unclear; Mg2+/Co2+ transporter complement(2718810..2719976) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174308 YP_001223162.1 CDS CMM_2417 NC_009480.1 2720024 2720866 R putative aldo/keto reductase (BAB99752.1| Aldo/keto reductases, related to diketogulonate reductase [Corynebacterium glutamicum ATCC 13032]; NP_788971.1| 2,5-diketo-D-gluconic acid reductase A [Tropheryma whipplei TW08/27]). pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative aldo/keto reductase complement(2720024..2720866) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173781 YP_001223163.1 CDS fadD NC_009480.1 2720863 2722449 R putative long-chain-fatty-acid-CoA ligase (ZP_00294061.1| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Thermobifida fusca]; NP_822779.1| putative acyl-CoA synthetase, long-chain fatty acid:CoA ligase [Streptomyces avermitilis MA-4680]). pfam00501, AMP-binding, AMP-binding enzyme. InterPro: AMP-dependent synthetase and ligase.; Specificity unclear; putative long-chain-fatty-acid-CoA ligase complement(2720863..2722449) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173485 YP_001223164.1 CDS CMM_2419 NC_009480.1 2722590 2726408 D putative ATP-dependent helicase (CAG20164.1| putative ATP-dependent helicase HrpA [Photobacterium profundum]; ZP_00292334.1| COG1643: HrpA-like helicases [Thermobifida fusca]). pfam00270, DEAD, DEAD/DEAH box helicase. pfam04408, HA2, Helicase associated domain (HA2). This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Function unclear; putative ATP-dependent helicase 2722590..2726408 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174959 YP_001223165.1 CDS CMM_2420 NC_009480.1 2726599 2728137 D putative peptide ABC transporter, substrate-binding protein (NP_631716.1| putative secreted solute-binding protein [Streptomyces coelicolor A3(2)]; ZP_00278819.1| COG0747: ABC-type dipeptide transport system, periplasmic component [Burkholderia fungorum LB400]). pfam00496,SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5. InterPro: Bacterial extracellular solute-binding protein family 5.; Specificity unclear; putative peptide ABC transporter substrate-binding protein 2726599..2728137 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174220 YP_001223166.1 CDS CMM_2421 NC_009480.1 2728134 2729108 D putative peptide ABC transporter, permease component ( NP_631717.1| putative metal transport integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00303394.1| COG0601: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Novosphingobium aromaticivorans DSM 12444]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative peptide ABC transporter permease 2728134..2729108 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173926 YP_001223167.1 CDS CMM_2422 NC_009480.1 2729105 2729929 D putative peptide ABC transporter, permease component (ZP_00364680.1| COG1173: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Polaromonas sp. JS666]; NP_105840.1| ABC transporter, permease protein [Mesorhizobium loti MAFF303099]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative peptide ABC transporter permease 2729105..2729929 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174677 YP_001223168.1 CDS CMM_2423 NC_009480.1 2729926 2731371 D putative peptide ABC transporter, ATP-binding protein (NP_631719.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]; NP_790103.1| peptide ABC transporter, ATP-binding protein [Pseudomonas syringae pv. tomato str. DC3000]). pfam00005, ABC_tran,ABC transporter (duplicated).; Specificity unclear; putative peptide ABC transporter ATP-binding protein 2729926..2731371 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173660 YP_001223169.1 CDS CMM_2424 NC_009480.1 2731414 2732382 R hypothetical protein complement(2731414..2732382) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174102 YP_001223170.1 CDS CMM_2425 NC_009480.1 2732379 2732978 R conserved membrane protein (NP_629518.1| putative membrane protein [Streptomyces coelicolor A3(2)]; YP_080528.1| hypothetical protein BL02151 [Bacillus licheniformis DSM 13]).; Conserved hypothetical protein; hypothetical protein complement(2732379..2732978) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175416 YP_001223171.1 CDS sseB NC_009480.1 2733969 2734817 R putative thiosulfate sulfurtransferase (YP_117233.1| putative thiosulfate sulfurtransferase [Nocardia farcinica]; ZP_00199189.1| COG2897: Rhodanese-related sulfurtransferase [Kineococcus radiotolerans SRS30216]). pfam00581, Rhodanese, Rhodanese-like domain (twice).; Specificity unclear; putative thiosulfate sulfurtransferase complement(2733969..2734817) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174414 YP_001223172.1 CDS CMM_2427 NC_009480.1 2734846 2735379 R putative acetyltransferase (ZP_00057878.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Thermobifida fusca]; NP_627391.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(2734846..2735379) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175899 YP_001223173.1 CDS nrdF NC_009480.1 2735514 2736509 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta complement(2735514..2736509) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175791 YP_001223174.1 CDS nrdA NC_009480.1 2736681 2739185 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(2736681..2739185) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174796 YP_001223175.1 CDS CMM_2430 NC_009480.1 2739562 2740773 D putative MFS permease (YP_062629.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787812.1| putative efflux protein [Tropheryma whipplei str. Twist]).; Function unclear; putative MFS permease 2739562..2740773 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173510 YP_001223176.1 CDS CMM_2431 NC_009480.1 2740869 2741342 D hypothetical protein 2740869..2741342 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174043 YP_001223177.1 CDS CMM_2432 NC_009480.1 2741410 2742402 R putative aldo/keto reductase (NP_631342.1| putative oxidoreducatse [Streptomyces coelicolor A3(2)]; ZP_00294378.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Thermobifida fusca]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity. InterPro: Aldo/keto reductase family.; Function unclear; putative aldo/keto reductase complement(2741410..2742402) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175467 YP_001223178.1 CDS CMM_2433 NC_009480.1 2742412 2742984 R Hypothetical protein; hypothetical protein complement(2742412..2742984) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174591 YP_001223179.1 CDS CMM_2434 NC_009480.1 2743501 2744685 D putative secreted serine protease, family S1C (NP_853797.1| PROBABLE SERINE PROTEASE PEPA [Mycobacterium bovis AF2122/97]; YP_121441.1| putative protease [Nocardia farcinica]). pfam00089, Trypsin, Trypsin. pfam00595, PDZ, PDZ domain (Also known as DHR or GLGF). PDZ domains are found in diverse signaling proteins.; Function unclear; secreted serine protease 2743501..2744685 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175739 YP_001223180.1 CDS abfA2 NC_009480.1 2744756 2746294 R putative alpha-L-arabinofuranosidase (Arabinosidase) (ZP_00199261.1| COG3534: Alpha-L-arabinofuranosidase [Kineococcus radiotolerans SRS30216]; NP_626674.1| alpha-L-arabinofuranosidase [Streptomyces coelicolor A3(2)]). , pfam06964, Alpha-L-AF_C, Alpha-L-arabinofuranosidase C-terminus.; Specificity unclear; putative alpha-L-arabinofuranosidase complement(2744756..2746294) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173255 YP_001223181.1 CDS CMM_2436 NC_009480.1 2746389 2747309 R putative L-arabinose ABC transporter, permease component (NP_631551.1| putative integral membrane binding-protein-dependent transport protein [Streptomyces coelicolor A3(2)]; NP_437582.1| putative sugar uptake ABC transporter permease protein [Sinorhizobium meliloti 1021]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative L-arabinose ABC transporter permease complement(2746389..2747309) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173005 YP_001223182.1 CDS CMM_2437 NC_009480.1 2747306 2748250 R putative L-arabinose ABC transporter, permease component (NP_631550.1| putative integral membrane binding-protein-dependent transport protein [Streptomyces coelicolor A3(2)]; NP_470102.1|; Specificity unclear; putative L-arabinose ABC transporter permease complement(2747306..2748250) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173001 YP_001223183.1 CDS CMM_2438 NC_009480.1 2748345 2749694 R putative L-arabinose ABC transporter, substrate binding protein (NP_631549.1| putative extracellular solute-binding protein [Streptomyces coelicolor A3(2)]; NP_437584.1| putative sugar uptake ABC transporter periplasmic solute-binding protein precursor [Sinorhizobium meliloti 1021]). pfam01547, SBP_bac_1,Bacterial extracellular solute-binding protein.; Specificity unclear; putative L-arabinose ABC transporter substrate binding protein complement(2748345..2749694) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175697 YP_001223184.1 CDS CMM_2439 NC_009480.1 2749799 2750800 R putative transcriptional regulator, LacI family (NP_625360.1| putative lacI-family transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00198050.1| COG1609: Transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; LacI family transcriptional regulator complement(2749799..2750800) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175657 YP_001223185.1 CDS CMM_2440 NC_009480.1 2750921 2751358 D hypothetical protein (YP_061780.1| hypothetical protein Lxx07550 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2750921..2751358 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173319 YP_001223186.1 CDS CMM_2441 NC_009480.1 2751378 2751773 R conserved membrane protein (NP_962814.1| hypothetical protein MAP3880 [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00291826.1| COG0477: Permeases of the major facilitator superfamily [Thermobifida fusca]).; hypothetical protein complement(2751378..2751773) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175180 YP_001223187.1 CDS CMM_2442 NC_009480.1 2751783 2753402 R putative methyltransferase (NP_627743.1| putative transferase [Streptomyces coelicolor A3(2)]; ZP_00292538.1| COG2890: Methylase of polypeptide chain release factors [Thermobifida fusca]). Interpro: SAM (and some other nucleotide) binding motif.; Family membership; putative methyltransferase complement(2751783..2753402) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175815 YP_001223188.1 CDS celB NC_009480.1 2753479 2755086 R putative secreted cellulase containing cellulose-binding domain (endo-1,4-beta-glucanase) (CAA44467.2| Cellulase [Clavibacter michiganensis]; YP_063040.1| cellulase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5). smart00637, CBD_II, CBD_II domain. InterPro: Glycoside hydrolase family 5.; Specificity unclear; cellulase complement(2753479..2755086) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175428 YP_001223189.1 CDS CMM_2444 NC_009480.1 2755424 2756392 R putative membrane protein (YP_061659.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789610.1| putative integral membrane protein [Tropheryma whipplei TW08/27]).; Conserved hypothetical protein; hypothetical protein complement(2755424..2756392) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175687 YP_001223190.1 CDS CMM_2445 NC_009480.1 2756479 2757147 R putative acetyltransferase (YP_061658.1| ribosomal-protein-alanine N-acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00059290.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Thermobifida fusca]; NP_824846.1| putative ribosomal- protein-alanine N-acetyltransferase [Streptomyces avermitilis MA-4680]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(2756479..2757147) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175968 YP_001223191.1 CDS galU NC_009480.1 2757205 2758101 R putative UTP-glucose-1-phosphate uridylyltransferase (YP_061657.1| UTP-glucose-1-phosphate uridylyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824850.1| putative UTP-glucose-1-phosphate uridylyltransferase [Streptomyces avermitilis MA-4680]). pfam00483, NTP_transferase, Nucleotidyl transferase. This family includes a wide range of enzymes which transfer nucleotides onto phosphosugars.; High confidence in function and specificity; putative UTP-glucose-1-phosphate uridylyltransferase complement(2757205..2758101) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173745 YP_001223192.1 CDS CMM_2447 NC_009480.1 2758142 2758717 D putative 5-formyltetrahydrofolate cyclo-ligase (YP_061656.1| 5-formyltetrahydrofolate cyclo-ligase-related protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_600108.1| 5-formyltetrahydrofolate cyclo-ligase [Corynebacterium glutamicum ATCC 13032]). pfam01812, 5-FTHF_cyc-lig, 5-formyltetrahydrofolate cyclo-ligase family. InterPro: 5-formyltetrahydrofolate cyclo-ligase.; Function unclear; putative 5-formyltetrahydrofolate cyclo-ligase 2758142..2758717 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174889 YP_001223193.1 CDS CMM_2448 NC_009480.1 2758724 2759131 D conserved hypothetical protein (only N-terminal similarities; NP_335453.1| hypothetical protein MT1020 [Mycobacterium tuberculosis CDC1551]; NP_627401.1| conserved hypothetical protein SCE22.04 [Streptomyces coelicolor A3(2);).; hypothetical protein 2758724..2759131 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173353 YP_001223194.1 CDS CMM_2449 NC_009480.1 2759160 2759642 D putative large-conductance mechanosensitive channel (YP_061654.1| large-conductance mechanosensitive channel [Leifsonia xyli subsp. xyli str. CTCB07]; NP_939223.1| large-conductance mechanosensitive channel [Corynebacterium diphtheriae]; NP_627404.1| putative mechanosensitive channel [Streptomyces coelicolor A3(2)]). pfam01741, MscL, Large-conductance mechanosensitive channel, MscL. InterPro: Large-conductance mechanosensitive channel mscL.; Function unclear; putative large-conductance mechanosensitive channel 2759160..2759642 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175289 YP_001223195.1 CDS CMM_2451 NC_009480.1 2759950 2763675 R conserved hypothetical protein (YP_061653.1| hypothetical protein Lxx05870 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789612.1| conserved large hypothetical protein [Tropheryma whipplei TW08/27]).; Family membership; hypothetical protein complement(2759950..2763675) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175666 YP_001223196.1 CDS CMM_2452 NC_009480.1 2764021 2764482 D putative fusion protein containg a putative transcriptional regulator, Cro/CI family and a nucleotidyltransferase (ZP_00186470.1| COG1396: Predicted transcriptional regulators [Rubrobacter xylanophilus DSM 9941]; AAP86029.1| putative nucleotidyl-transferase [Ralstonia eutropha]). N-terminal: pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. InterPro: Helix-turn-helix motif. C-terminal: pfam01909, NTP_transf_2,Nucleotidyltransferase domain.; Conserved hypothetical protein; Cro/CI family transcriptional regulator /nucleotidyltransferase 2764021..2764482 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175451 YP_001223197.1 CDS CMM_2453 NC_009480.1 2764482 2764814 D conserved hypothetical protein (ZP_00178030.1| COG2361: Uncharacterized conserved protein [Crocosphaera watsonii WH 8501]; NP_634631.1| nucleotidyltransferase [Methanosarcina mazei Go1]). pfam01934, DUF86, Protein of unknown function DUF86.; hypothetical protein 2764482..2764814 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174536 YP_001223198.1 CDS CMM_2454 NC_009480.1 2764825 2765937 R conserved hypothetical protein, putative restriction enzyme (ZP_00128036.1| COG4748: Uncharacterized conserved protein [Pseudomonas syringae pv. syringae B728a]; NP_801082.1| hypothetical protein VPA1572 [Vibrio parahaemolyticus RIMD 2210633]; NP_601625.1| predicted type IV restriction endonuclease [Corynebacterium glutamicum ATCC 13032]). pfam04313,HSDR_N, Type I restriction enzyme R protein N terminus (HSDR_N). This family consists of a number of N terminal regions found in type I restriction enzyme R (HSDR) proteins.; Function unclear; putative restriction enzyme complement(2764825..2765937) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175737 YP_001223199.1 CDS CMM_2455 NC_009480.1 2766824 2768191 D putative cytosine/purine permease, NCS1 family (NP_624885.1| putative cytosine permease [Streptomyces coelicolor A3(2)]; YP_049041.1| permease [Erwinia carotovora subsp. atroseptica SCRI1043]). pfam02133,Transp_cyt_pur, Permease for cytosine/purines, uracil,thiamine, allantoin.; Specificity unclear; cytosine/purine permease NCS1 family 2766824..2768191 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175047 YP_001223200.1 CDS CMM_2456 NC_009480.1 2768188 2769747 D putative hydantoinase (NP_085687.1| hydantoinase [Mesorhizobium loti MAFF303099]; NP_242750.1| hydantoinase [Bacillus halodurans C-125]). pfam05378,Hydant_A_N, Hydantoinase/oxoprolinase N-terminal region. pfam01968, Hydantoinase_A, Hydantoinase/oxoprolinase. This family includes the enzymes hydantoinase and oxoprolinase EC:3.5.2.9. Both reactions involve the hydrolysis of 5-membered rings via hydrolysis of their internal imide bonds.; Specificity unclear; putative hydantoinase 2768188..2769747 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175519 YP_001223201.1 CDS CMM_2457 NC_009480.1 2769740 2770855 D conserved hypothetical protein (YP_013096.1| conserved hypothetical protein [Listeria monocytogenes str. 4b F2365]; ZP_00197761.1| COG3535: Uncharacterized conserved protein [Mesorhizobium sp. BNC1]). pfam06032,DUF917, Protein of unknown function (DUF917).; Function unclear; hypothetical protein 2769740..2770855 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175480 YP_001223202.1 CDS CMM_2458 NC_009480.1 2770882 2771997 D conserved hypothetical protein (EAL09859.1| conserved hypothetical protein [Listeria monocytogenes str. 4b H7858] ; NP_085686.1| hypothetical protein mll9130 [Mesorhizobium loti MAFF303099]). pfam06032, DUF917,Protein of unknown function (DUF917).; hypothetical protein 2770882..2771997 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174060 YP_001223203.1 CDS CMM_2459 NC_009480.1 2771994 2773559 D conserved hypothetical protein, putative regulatory protein (ZP_00059062.1| COG2508: Regulator of polyketide synthase expression [Thermobifida fusca]; NP_631097.1| putative regulatory protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 2771994..2773559 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173670 YP_001223204.1 CDS CMM_2460 NC_009480.1 2773568 2775175 R Function unclear; putative ATPase complement(2773568..2775175) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173889 YP_001223205.1 CDS CMM_2461 NC_009480.1 2775387 2776169 D conserved hypothetical protein (ZP_00063576.1| COG0009: Putative translation factor (SUA5) [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293]; NP_781010.1| SUA5 protein [Clostridium tetani E88]). pfam01300, Sua5_yciO_yrdC, yrdC domain. This domain has been shown to preferentially bind to dsRNA.; Function unclear; hypothetical protein 2775387..2776169 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175078 YP_001223206.1 CDS CMM_2462 NC_009480.1 2776527 2776877 D conserved hypothetical protein, putative Lsr2-like protein (YP_062335.1| hypothetical protein Lxx14130 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198461.1| hypothetical protein Krad06003802 [Kineococcus radiotolerans SRS30216]; YP_118525.1| putative LSR2 protein [Nocardia farcinica]).; Function unclear; putative Lsr2-like protein 2776527..2776877 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172917 YP_001223207.1 CDS CMM_2463 NC_009480.1 2777098 2778465 D hypothetical protein (weak similarity to low GC Gram-positive surface proteins and RTX toxins).; hypothetical protein 2777098..2778465 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175335 YP_001223208.1 CDS CMM_2464 NC_009480.1 2778699 2779463 D putative transcriptional activator (NP_821574.1| putative transcriptional regulator [Streptomyces avermitilis MA-4680]; AAP42853.1| NanR1 [Streptomyces nanchangensis]). pfam03704, BTAD, Bacterial transcriptional activator domain. Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production.; Function unclear; putative transcriptional activator 2778699..2779463 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175427 YP_001223209.1 CDS CMM_2465 NC_009480.1 2779506 2781578 R putative serine protease, family S9A (NP_638852.1| prolyl oligopeptidase [Xanthomonas campestris pv. campestris str. ATCC 33913]; NP_962885.1| hypothetical protein MAP3951c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam02897, Peptidase_S9_N,Prolyl oligopeptidase, N-terminal beta-propeller domain. pfam00326, Peptidase_S9, Prolyl oligopeptidase family. InterPro: Prolyl oligopeptidase N-terminal beta-propeller domain.; Specificity unclear; serine protease complement(2779506..2781578) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175157 YP_001223210.1 CDS CMM_2466 NC_009480.1 2781613 2782110 R putative restriction endonuclease (YP_062634.1| hypothetical protein Lxx17860 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_961224.1| hypothetical protein MAP2290c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00058752.1| COG1403: Restriction endonuclease [Thermobifida fusca]). pfam01844, HNH, HNH endonuclease. InterPro: HNH nuclease.; Specificity unclear; putative restriction endonuclease complement(2781613..2782110) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174873 YP_001223211.1 CDS CMM_2467 NC_009480.1 2782470 2783414 R putative secreted hydrolase (NP_787417.1| NPL/P60 family secreted protein [Tropheryma whipplei str. Twist]; NP_780938.1| putative cell wall-associated hydrolase [Clostridium tetani E88]). pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.; Function unclear; putative secreted hydrolase complement(2782470..2783414) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173128 YP_001223212.1 CDS dtxR NC_009480.1 2783738 2784436 R putative iron-dependent repressor (YP_062636.1| iron-dependent repressor, DxtR metalloregulatory family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628563.1| iron repressor [Streptomyces coelicolor A3(2)]; AAF36925.1| transcriptional regulatory protein DtxR [Rhodococcus erythropolis]). pfam01325, Fe_dep_repress,Iron dependent repressor, N-terminal DNA binding domain. This family includes the Diphtheria toxin repressor. DNA binding is through a helix-turn-helix motif. pfam02742,Fe_dep_repr_C, Iron dependent repressor, metal binding and dimerisation domain. This family includes the Diphtheria toxin repressor. pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.; Specificity unclear; putative iron-dependent repressor complement(2783738..2784436) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174990 YP_001223213.1 CDS serC NC_009480.1 2784545 2785663 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 2784545..2785663 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173362 YP_001223214.1 CDS CMM_2470 NC_009480.1 2785736 2786401 R conserved hypothetical protein (YP_062639.1| hypothetical protein Lxx17910 [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055188.1| hypothetical protein PPA0478 [Propionibacterium acnes KPA171202]).; hypothetical protein complement(2785736..2786401) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173279 YP_001223215.1 CDS cspB NC_009480.1 2786394 2786777 R putative cold-shock protein (YP_062640.1| cold shock protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00059156.1| COG1278: Cold shock proteins [Thermobifida fusca]; NP_628496.1| cold shock protein B [Streptomyces coelicolor A3(2)]). pfam00313, CSD, 'Cold-shock' DNA-binding domain. smart00357, CSP, Cold shock protein domain; RNA-binding domain that functions as a RNA-chaperone in bacteria and is involved in regulating translation in eukaryotes. Contains sub-family of RNA-binding domains in the Rho transcription termination factor. InterPro: Cold-shock DNA-binding domain.; Function unclear; putative cold shock protein complement(2786394..2786777) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173157 YP_001223216.1 CDS CMM_2472 NC_009480.1 2786936 2787205 D hypothetical membrane protein (YP_062641.1| hypothetical protein Lxx17930 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2786936..2787205 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174978 YP_001223217.1 CDS CMM_2473 NC_009480.1 2787216 2789102 D putative DNA binding protein (YP_062642.1| hypothetical protein Lxx17940 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_302419.1| possible DNA-binding protein [Mycobacterium leprae]; NP_737502.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; Function unclear; hypothetical protein 2787216..2789102 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173196 YP_001223218.1 CDS CMM_2474 NC_009480.1 2789099 2790763 D putative ATP-dependent DNA helicase (YP_062643.1| DNA repair helicase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825089.1| putative ATP-dependent DNA helicase [Streptomyces avermitilis MA-4680]; ZP_00226628.1| COG1061: DNA or RNA helicases of superfamily II [Kineococcus radiotolerans SRS30216]). pfam00270, DEAD,DEAD/DEAH box helicase. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Function unclear; putative ATP-dependent DNA helicase 2789099..2790763 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174494 YP_001223219.1 CDS CMM_2475 NC_009480.1 2790841 2791533 D putative two component system response regulator (YP_062646.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787175.1| two-component system response regulator [Tropheryma whipplei str. Twist]; ZP_00198812.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Kineococcus radiotolerans SRS30216]). pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. pfam00486, Trans_reg_C, Transcriptional regulatory protein, C terminal. InterPro: Response regulator receiver domain.; Specificity unclear; putative two component system response regulator 2790841..2791533 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175503 YP_001223220.1 CDS CMM_2476 NC_009480.1 2791654 2793414 D putative two-component system sensor kinase (YP_062647.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226631.1| COG0642: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]; ZP_00081281.1| COG0642: Signal transduction histidine kinase [Geobacter metallireducens]). pfam00672, HAMP, HAMP domain. pfam00512, HisKA, His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 2791654..2793414 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173163 YP_001223221.1 CDS CMM_2477 NC_009480.1 2793461 2793751 D conserved hypothetical protein, 6 kDa early secretory antigenic target (ESAT-6) homolog (ZP_00198816.2| COG4842: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_695234.1| hypothetical protein BL0003 [Bifidobacterium longum NCC2705]). pfam06013, DUF909, Bacterial protein of unknown function (DUF909). This family consists of several short bacterial proteins of unknown function.; Function unclear; hypothetical protein 2793461..2793751 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173173 YP_001223222.1 CDS groEL NC_009480.1 2793882 2795501 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(2793882..2795501) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173120 YP_001223223.1 CDS cspA2 NC_009480.1 2795691 2795909 R putative cold shock protein (YP_062650.1| cold-shock protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825109.1| putative cold shock protein [Streptomyces avermitilis MA-4680]; ZP_00228151.1| COG1278: Cold shock proteins [Kineococcus radiotolerans SRS30216]). pfam00313,CSD, 'Cold-shock' DNA-binding domain. InterPro: Cold-shock DNA-binding domain.; Function unclear; putative cold shock protein complement(2795691..2795909) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173973 YP_001223224.1 CDS CMM_2480 NC_009480.1 2796130 2796702 R hypothetical protein (YP_062651.1| hypothetical protein Lxx18030 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_334855.1| tuberculin related peptide [Mycobacterium tuberculosis CDC1551]; NP_940367.1| Putative secreted protein [Corynebacterium diphtheriae NCTC 13129]). 2a75: L-lysine exporter; hypothetical protein complement(2796130..2796702) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175148 YP_001223225.1 CDS CMM_2481 NC_009480.1 2796737 2797066 R conserved hypothetical protein (YP_062652.1| hypothetical protein Lxx18040 [Leifsonia xyli subsp. xyli str. CTCB07]; CAB06570.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; ZP_00059146.1| hypothetical protein [Thermobifida fusca]).; hypothetical protein complement(2796737..2797066) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173851 YP_001223226.1 CDS CMM_2482 NC_009480.1 2797303 2797704 D conserved hypothetical protein, putative methionine sulfoxide reductase (YP_062653.1| oxidoreductase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_630170.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; CAB02327.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam01641, SelR, SelR domain. Methionine sulfoxide reduction is an important process, by which cells regulate biological processes and cope with oxidative stress.; Function unclear; putative methionine sulfoxide reductase 2797303..2797704 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174289 YP_001223227.1 CDS CMM_2483 NC_009480.1 2797710 2798309 D conserved hypothetical protein, putative nitroreductase (YP_062654.1| nitroreductase [Leifsonia xyli subsp. xyli str. CTCB07]P24250|YDJA_ECOLI Protein ydjA; NP_460262.1| putative oxidoreductase [Salmonella typhimurium LT2]). pfam00881, Nitroreductase,Nitroreductase family. Members of this family utilise FMN as a cofactor.; Function unclear; putative nitroreductase 2797710..2798309 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173619 YP_001223228.1 CDS CMM_2484 NC_009480.1 2798439 2799356 R conserved hypothetical protein (YP_062663.1| hypothetical protein Lxx18180 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789357.1| putative secreted protein [Tropheryma whipplei TW08/27]).; Function unclear; hypothetical protein complement(2798439..2799356) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174818 YP_001223229.1 CDS CMM_2485 NC_009480.1 2799672 2800772 D putative sugar ABC transporter, ATP-binding protein (YP_062664.1| glycerol-phosphate porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628414.1| ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Function unclear; putative sugar ABC transporter ATP-binding protein 2799672..2800772 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174158 YP_001223230.1 CDS CMM_2486 NC_009480.1 2800874 2802178 D conserved hypothetical protein (YP_062665.1| hypothetical protein Lxx18190 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_938914.1| hypothetical protein DIP0538 [Corynebacterium diphtheriae NCTC 13129]).; hypothetical protein 2800874..2802178 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174189 YP_001223231.1 CDS CMM_2487 NC_009480.1 2802251 2803321 R putative tRNA/rRNA methyltransferase (ZP_00225978.1| COG0566: rRNA methylases [Kineococcus radiotolerans SRS30216]; NP_601840.1| rRNA methylase [Corynebacterium glutamicum ATCC 13032]). InterPro: RNA methyltransferase TrmH family group 3 pfam00588,SpoU_methylase, SpoU rRNA Methylase family. This family of proteins probably use S-AdoMet. TIGRFam: rRNA_methyl_3: RNA methyltransferase; Specificity unclear; putative tRNA/rRNA methyltransferase complement(2802251..2803321) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173357 YP_001223232.1 CDS cysS NC_009480.1 2803311 2804765 R cysS1; catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(2803311..2804765) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173056 YP_001223233.1 CDS ispDF NC_009480.1 2804849 2806081 R putative IspDF bifunctional enzyme (N-terminally: COG1211, IspD, 4-diphosphocytidyl- 2-methyl-D-erithritol synthase, EC 2.7.7.60; C-terminally: COG0245, IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, EC 4.6.1.12) (NP_787476.1| IspD; IspF [Tropheryma whipplei str. Twist]; NP_698125.1| 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/ 4-diphosphocytidyl-2C-methyl-D-erythritol synthase [Brucella suis 1330]). Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol 4-phosphate (ispD) and converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 24- cyclodiphosphate and CMP (ispF). Also converts 4-diphosphocytidyl- 2C-methyl-D-erythritol into 2C-methyl-D-erythritol 34- cyclophosphate and CMP (ispF) (By similarity). InterPro: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase ispD: 4-diphosphocytidyl-2C-methyl-D-e; High confidence in function and specificity; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(2804849..2806081) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174582 YP_001223234.1 CDS CMM_2490 NC_009480.1 2806125 2806607 R putative transcriptional regulator, CarD family (ZP_00198110.2| COG1329: Transcriptional regulators, ; NP_301347.1| putative transcription factor [Mycobacterium leprae]). InterPro: Transcription factor CarD pfam02559,CarD_TRCF, CarD-like/TRCF domain. CarD is a Myxococcus xanthus protein required for the activation of light- and starvation- inducible genes. This domain is involved in binding to the stalled RNA polymerase.; Specificity unclear; CarD family transcriptional regulator complement(2806125..2806607) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173812 YP_001223235.1 CDS CMM_2491 NC_009480.1 2806771 2807337 D hypothetical protein 2806771..2807337 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173686 YP_001223236.1 CDS CMM_2492 NC_009480.1 2807423 2808103 R putative two-component system response regulator (CAB00952.1| TWO COMPONENT SENSORY TRANSDUCTION PROTEIN REGX3 (TRANSCRIPTIONAL REGULATORY PROTEIN) (PROBABLY LUXR-FAMILY)[Mycobacterium tuberculosis H37Rv]; NP_938772.1| Putative two component system response regulator [Corynebacterium diphtheriae]). pfam00072, Response_reg,Response regulator receiver domain. pfam00486,Trans_reg_C, Transcriptional regulatory protein, C terminal.; Specificity unclear; putative two-component system response regulator complement(2807423..2808103) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175436 YP_001223237.1 CDS CMM_2493 NC_009480.1 2808100 2809263 R two-component system sensor kinase (NP_825150.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; ZP_00058811.1| COG0642: Signal transduction histidine kinase [Thermobifida fusca]). InterPro: Histidine kinase C-terminal pfam00512, HisKA,His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518,HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase complement(2808100..2809263) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173109 YP_001223238.1 CDS phoU NC_009480.1 2809468 2810121 D putative phosphate transport system regulator (NP_825151.1| putative phosphate transport system regulatory protein [Streptomyces avermitilis MA-4680]; ZP_00225901.1| COG0704: Phosphate uptake regulator [Kineococcus radiotolerans SRS30216]). pfam01895, PhoU,PhoU family. This family contains phosphate regulatory proteins including PhoU. (twice); High confidence in function and specificity; putative phosphate transport system regulator 2809468..2810121 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173073 YP_001223239.1 CDS gpmA NC_009480.1 2810206 2810961 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(2810206..2810961) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173777 YP_001223240.1 CDS CMM_2496 NC_009480.1 2810997 2811809 D putative methylase (ZP_00198230.1| COG2890: Methylase of polypeptide chain release factors [Kineococcus radiotolerans SRS30216]; NP_825184.1| hypothetical protein SAV4007 [Streptomyces avermitilis MA-4680]). InterPro: SAM (and some other nucleotide) binding motif surE: stationary-phase survival protein; Function unclear; hypothetical protein 2810997..2811809 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175683 YP_001223241.1 CDS CMM_2497 NC_009480.1 2811806 2812927 R putative membrane protein (ZP_00227637.1| COG4129: Predicted membrane protein [Kineococcus radiotolerans SRS30216]; NP_739210.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; Function unclear; hypothetical protein complement(2811806..2812927) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175186 YP_001223242.1 CDS CMM_2498 NC_009480.1 2812911 2814065 R putative aminomethyltransferase (ZP_00198226.1| COG0354: Predicted aminomethyltransferase related to GcvT [Kineococcus radiotolerans SRS30216]; NP_825205.1| hypothetical protein SAV4028 [Streptomyces avermitilis MA-4680]). InterPro: Glycine cleavage T-protein (aminomethyl transferase). gcvT: glycine cleavage system T protein. pfam01571, GCV_T, Glycine cleavage T-protein (aminomethyl transferase).; Function unclear; putative aminomethyltransferase complement(2812911..2814065) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173330 YP_001223243.1 CDS CMM_2499 NC_009480.1 2814055 2814654 R conserved hypothetical protein (ZP_00198224.2| hypothetical protein Krad06004263 [Kineococcus radiotolerans SRS30216]; ZP_00293141.1| COG1185: Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) [Thermobifida fusca]).; hypothetical protein complement(2814055..2814654) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173663 YP_001223244.1 CDS CMM_2499A NC_009480.1 2814666 2814782 R hypothetical protein (ZP_01130428.1| hypothetical protein A20C1_06691 [marine actinobacterium PHSC20C1]; AAT89577.1| hypothetical protein Lxx18360 [Leifsonia xyli subsp. xyli str. CTCB07]); hypothetical protein complement(2814666..2814782) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173591 YP_001223245.1 CDS CMM_2500 NC_009480.1 2814826 2815092 R Hypothetical protein; hypothetical protein complement(2814826..2815092) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173894 YP_001223246.1 CDS glnR NC_009480.1 2815146 2815844 D transcriptional regulator (NP_825219.1| putative GlnR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; Q05943|GLNR_STRCO Transcriptional regulatory protein glnR). InterPro: Transcriptional regulatory protein C terminal pfam00486, Trans_reg_C,Transcriptional regulatory protein, C terminal.; Specificity unclear; transcriptional regulator 2815146..2815844 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173385 YP_001223247.1 CDS CMM_2502 NC_009480.1 2815807 2816727 D putative acetyltransferase (NP_628328.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]; CAA17625.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions (twice). InterPro: GCN5-related N-acetyltransferase.; Function unclear; putative acetyltransferase 2815807..2816727 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175001 YP_001223248.1 CDS ppkA NC_009480.1 2816821 2819004 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2816821..2819004 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173356 YP_001223249.1 CDS CMM_2504 NC_009480.1 2819046 2819987 D putative NTP pyrophosphohydrolase (NP_961957.1| MutT1 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_600538.1| NTP pyrophosphohydrolase [Corynebacterium glutamicum ATCC 13032]). pfam00293,NUDIX, NUDIX domain. C-terminally second domain: COG2062,SixA, Phosphohistidine phosphatase.; Function unclear; putative NTP pyrophosphohydrolase 2819046..2819987 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175438 YP_001223250.1 CDS pstS NC_009480.1 2820187 2821284 D phosphate ABC transporter, substrate-binding protein (ZP_00293017.1| COG0226: ABC-type phosphate transport system, periplasmic component [Thermobifida fusca]; NP_695519.1| phosphate-binding transport protein of ABC transporter system [Bifidobacterium longum NCC2705]).; High confidence in function and specificity; phosphate ABC transporter substrate-binding protein 2820187..2821284 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173251 YP_001223251.1 CDS pstC NC_009480.1 2821392 2822402 D Phosphate ABC transporter, permease component (ZP_00293018.1| COG0573: ABC-type phosphate transport system, permease component [Thermobifida fusca]; NP_628318.1| phosphate ABC transport system permease protein [Streptomyces coelicolor A3(2)]). InterPro: Binding-protein-dependent transport systems inner membrane component.; High confidence in function and specificity; phosphate ABC transporter permease 2821392..2822402 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175608 YP_001223252.1 CDS pstA NC_009480.1 2822402 2823502 D phosphate ABC transporter, permease component (ZP_00293019.1| COG0581: ABC-type phosphate transport system, permease component [Thermobifida fusca]; NP_825251.1| putative phosphate ABC transporter permease protein [Streptomyces avermitilis MA-4680]). InterPro: Binding-protein-dependent transport systems inner membrane component. pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; High confidence in function and specificity; phosphate ABC transporter permease 2822402..2823502 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174080 YP_001223253.1 CDS pstB NC_009480.1 2823546 2824325 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 2823546..2824325 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174733 YP_001223254.1 CDS CMM_2509 NC_009480.1 2824407 2825270 R conserved membrane protein (NP_827759.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00228329.1| hypothetical protein Krad06001631 [Kineococcus radiotolerans SRS30216]). weak similarity to: COG5343, COG5343, Uncharacterized protein conserved in bacteria.; Function unclear; hypothetical protein complement(2824407..2825270) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173717 YP_001223255.1 CDS sigK NC_009480.1 2825267 2825857 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins; RNA polymerase sigma factor SigK complement(2825267..2825857) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173541 YP_001223256.1 CDS CMM_2511 NC_009480.1 2826425 2827057 R hypothetical protein (ZP_00206537.1| hypothetical protein Blon021115 [Bifidobacterium longum DJO10A]; ZP_00226802.1| hypothetical protein Krad06002674 [Kineococcus radiotolerans).; hypothetical protein complement(2826425..2827057) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174421 YP_001223257.1 CDS CMM_2512 NC_009480.1 2827274 2828314 R putative acyltransferase (NP_945889.1| Acyltransferase 3 family [Rhodopseudomonas palustris CGA009]; NP_738686.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam01757,Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes.; Function unclear; putative acyltransferase complement(2827274..2828314) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174046 YP_001223258.1 CDS CMM_2513 NC_009480.1 2828591 2829256 D hypothetical esterase (only weak similarities in C-terminal half to: NP_387325.1| PUTATIVE ACYL-COA THIOESTERASE I PROTEIN [Sinorhizobium meliloti 1021]; ZP_00244751.1| COG2755: Lysophospholipase L1 and related esterases [Rubrivivax gelatinosus PM1]). weak similarity to: pfam00657, Lipase_GDSL, GDSL-like Lipase/Acylhydrolase.; Hypothetical protein; esterase 2828591..2829256 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173063 YP_001223259.1 CDS CMM_2514 NC_009480.1 2829282 2830661 R hypothetical protein complement(2829282..2830661) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174016 YP_001223260.1 CDS CMM_2515 NC_009480.1 2830903 2831148 D hypothetical protein 2830903..2831148 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175116 YP_001223261.1 CDS CMM_2516 NC_009480.1 2831145 2832065 R putative aldose-1-epimerase (NP_696524.1| hypothetical protein in aldose epimerase family [Bifidobacterium longum NCC2705]; ZP_00291742.1| COG2017: Galactose mutarotase and related enzymes [Thermobifida fusca]). pfam01263, Aldose_epim, Aldose 1-epimerase.; Specificity unclear; putative aldose-1-epimerase complement(2831145..2832065) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174804 YP_001223262.1 CDS CMM_2517 NC_009480.1 2832076 2832903 R putative transcriptional regulator, DeoT family (NP_624108.1| Transcriptional regulator of sugar metabolism [Thermoanaerobacter tengcongensis]; ZP_00180163.2| COG1349: Transcriptional regulators of sugar metabolism [Moorella thermoacetica ATCC 39073]). pfam00455, DeoR, Bacterial regulatory proteins, deoR family.; Specificity unclear; DeoR family transcriptional regulator complement(2832076..2832903) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175405 YP_001223263.1 CDS galT NC_009480.1 2832997 2834139 D Galactose-1-phosphate uridylyltransferase (UDP-glucose-hexose- 1-phosphate uridylyltransferase) (ZP_00226399.1| COG1085: Galactose-1-phosphate uridylyltransferase [Kineococcus radiotolerans SRS30216]; NP_939376.1| Galactose-1-phosphate uridylyltransferase [Corynebacterium diphtheriae NCTC 13129]). InterPro: Galactose-1-phosphate uridyl transferase. pfam01087,GalP_UDP_transf, Galactose-1-phosphate uridyl transferase,N-terminal domain. pfam02744, GalP_UDP_tr_C, Galactose-1-phosphate uridyl transferase, C-terminal domain.; High confidence in function and specificity; hypothetical protein 2832997..2834139 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175240 YP_001223264.1 CDS galK NC_009480.1 2834136 2835296 D Galactokinase (Galactose kinase) (Q9K3S8|GAL1_STRCO Galactokinase (Galactose kinase); ZP_00120571.1| COG0153: Galactokinase [Bifidobacterium longum DJO10A]). InterPro: Galactokinase. pfam00288, GHMP_kinases, GHMP kinases putative ATP-binding protein.; High confidence in function and specificity; hypothetical protein 2834136..2835296 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174864 YP_001223265.1 CDS CMM_2520 NC_009480.1 2835369 2835974 D putative acetyltransferase (NP_828214.1| putative siderophore binding protein [Streptomyces avermitilis MA-4680]; ZP_00084142.1| COG0663: Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [Pseudomonas fluorescens PfO-1]). InterPro: Bacterial transferase hexapeptide repeat. cd00208, LbetaH,Left-Handed Parallel beta-Helix; Proteins containing hexapeptide repeats are often enzymes showing acyl-transferase activity, many are trimeric in their active form.; Function unclear; putative acetyltransferase/ siderophore binding protein 2835369..2835974 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174824 YP_001223266.1 CDS folD NC_009480.1 2836038 2836940 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(2836038..2836940) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174280 YP_001223267.1 CDS glyA NC_009480.1 2836937 2838214 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(2836937..2838214) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173583 YP_001223268.1 CDS CMM_2523 NC_009480.1 2838511 2840157 D putative glycosidase, possible alpha-amylase (AAM51152.1| amylosucrase Ams [Neisseria meningitidis]; ZP_00293345.1| COG0366: Glycosidases [Thermobifida fusca]). pfam00128, Alpha-amylase, Alpha amylase,catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases.; Specificity unclear; putative glycosidase 2838511..2840157 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175553 YP_001223269.1 CDS CMM_2524 NC_009480.1 2840198 2840698 D hypothetical membrane protein; hypothetical protein 2840198..2840698 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175458 YP_001223270.1 CDS CMM_2525 NC_009480.1 2840729 2841586 R putative transcriptional regulator, LysR family (NP_823021.1| putative LysR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; ZP_00198639.2| COG0583: Transcriptional regulator [Kineococcus radiotolerans SRS30216]). pfam00126, HTH_1,Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate, LysR substrate binding domain. The structure of this domain is known and is; Specificity unclear; hypothetical protein complement(2840729..2841586) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175372 YP_001223271.1 CDS CMM_2526 NC_009480.1 2841743 2843209 D putative efflux MFS permease (NP_825071.1| putative integral membrane efflux protein [Streptomyces avermitilis MA-4680]; ZP_00227648.1| COG0477: permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam05977, DUF894, Bacterial protein of unknown function (DUF894). 2A0121: H+ Antiporter protein. COG2814, AraJ, Arabinose efflux permease.; Specificity unclear; putative MFS permease 2841743..2843209 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175642 YP_001223272.1 CDS CMM_2527 NC_009480.1 2843118 2844149 R putative oxidoreductase (ZP_00226289.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; BAB79295.1| putative oxidoreductase [Streptomyces griseus]). pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Specificity unclear; putative oxidoreductase complement(2843118..2844149) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174461 YP_001223273.1 CDS sirR NC_009480.1 2844268 2844942 D putative manganese/iron-dependent repressor (C70884 probable transcription repressor sirR - Mycobacterium tuberculosis (strain H37RV); ZP_00226601.1| COG1321: Mn-dependent transcriptional regulator [Kineococcus radiotolerans SRS30216]). smart00529, HTH_DTXR, Helix-turn-helix diphteria tox regulatory element; iron dependent repressor. pfam02742, Fe_dep_repr_C, Iron dependent repressor, metal binding and dimerisation domain. This family includes the Diphtheria toxin repressor. pfam01325,Fe_dep_repress, Iron dependent repressor, N-terminal DNA binding domain. This family includes the Diphtheria toxin repressor. DNA binding is through a helix-turn-helix motif.; Specificity unclear; hypothetical protein 2844268..2844942 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174501 YP_001223274.1 CDS mntH NC_009480.1 2844964 2846214 R putative manganese transporter, NRAMP family (AAS20095.1| H+-stimulated manganese uptake system protein [Arthrobacter aurescens]; O05916|MNTH_MYCTU Probable manganese transport protein mntH (BRAMP)). InterPro: Natural resistance-associated macrophage protein pfam01566, Nramp, Natural resistance-associated macrophage protein.; High confidence in function and specificity; manganese transporter complement(2844964..2846214) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175167 YP_001223275.1 CDS CMM_2530 NC_009480.1 2846343 2847263 R hypothetical protein (ZP_00198979.1| hypothetical protein Krad06002582 [Kineococcus radiotolerans SRS30216]).; hypothetical protein complement(2846343..2847263) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175653 YP_001223276.1 CDS CMM_2531 NC_009480.1 2847322 2848626 R putative sugar MFS-permease (NP_789043.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; ZP_00227340.1| COG2814: Arabinose efflux permease [Kineococcus radiotolerans SRS30216]). pfam00083,Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative sugar MFS-permease complement(2847322..2848626) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175771 YP_001223277.1 CDS purU NC_009480.1 2848705 2849577 D putative formyltetrahydrofolate deformylase (ZP_00226393.1| COG0788: Formyltetrahydrofolate hydrolase [Kineococcus radiotolerans SRS30216]; ZP_00215833.1| COG0788: Formyltetrahydrofolate hydrolase [Burkholderia cepacia R18194]). InterPro: Formyltetrahydrofolate deformylase. pfam01842, ACT, ACT domain. This family of domains generally have a regulatory role. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. pfam00551,Formyl_trans_N, Formyl transferase. PurU: formyltetrahydrofolate deformylase; High confidence in function and specificity; putative formyltetrahydrofolate deformylase 2848705..2849577 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175659 YP_001223278.1 CDS CMM_2533 NC_009480.1 2849608 2850462 R putative ABC-transporter, permease component (ZP_00225856.1| COG0842: ABC-type multidrug transport system, permease component [Kineococcus radiotolerans SRS30216]; NP_629116.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]). Mtu_efflux: ABC transporter efflux protein; Specificity unclear; putative ABC-transporter, permease complement(2849608..2850462) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174517 YP_001223279.1 CDS CMM_2534 NC_009480.1 2850459 2851523 R putative ABC transporter ATP-binding protein (NP_629115.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]; ZP_00198185.1| COG1131: ABC-type multidrug transport system, ATPase component [Kineococcus radiotolerans SRS30216]). pfam00005,ABC_tran, ABC transporter.; Specificity unclear; hypothetical protein complement(2850459..2851523) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175972 YP_001223280.1 CDS sbtB NC_009480.1 2851656 2855336 R putative serine protease, peptidase family S8A (Subtilase) (T05768 subtilisin-like proteinase (EC 3.4.21.-) - Arabidopsis thaliana; T07172 subtilisin-like proteinase (EC 3.4.21.-) 2 - tomato). , pfam05922,Subtilisin_N, Subtilisin N-terminal Region. This family is found at the N-terminus of a number of subtilisins. It is cleaved prior to activation of the enzyme. , pfam00082,Peptidase_S8, Subtilase family. , pfam02225, PA, PA domain. The PA (Protease associated) domain is found as an insert domain in diverse proteases.; Specificity unclear; serine protease complement(2851656..2855336) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174928 YP_001223281.1 CDS sbtC NC_009480.1 2855583 2859182 R putative subtilisin-like serine protease, peptidase family S8 (T07172 subtilisin-like proteinase (EC 3.4.21.-) 2 - tomato; T05768 subtilisin-like proteinase (EC 3.4.21.-) - Arabidopsis thaliana). pfam05922, Subtilisin_N,Subtilisin N-terminal Region. This family is found at the N-terminus of a number of subtilisins. It is cleaved prior to activation of the enzyme. pfam00082, Peptidase_S8,Subtilase family. Subtilases are a family of serine proteases. pfam02225, PA, PA domain. The PA (Protease associated) domain is found as an insert domain in diverse proteases.; Specificity unclear; subtilisin-like serine protease,peptidase family S8 complement(2855583..2859182) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175787 YP_001223282.1 CDS icdA NC_009480.1 2859432 2860646 R Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase complement(2859432..2860646) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174024 YP_001223283.1 CDS CMM_2538 NC_009480.1 2860890 2861333 D putative acetyltransferase (YP_062775.1| spermidine acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628451.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; hypothetical protein 2860890..2861333 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175765 YP_001223284.1 CDS CMM_2539 NC_009480.1 2861337 2861657 D Region created by contig update; putative methylated DNA-protein cysteine methyltransferase 2861337..2861657 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175083 YP_001223285.1 CDS CMM_2540 NC_009480.1 2861712 2862218 D hypothetical protein 2861712..2862218 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173728 YP_001223286.1 CDS CMM_2541 NC_009480.1 2862295 2864103 R putative ABC transporter, fused permease and ATP-binding protein (NP_629587.1| putative ABC transporter [Streptomyces coelicolor A3(2)]; NP_622488.1| ABC-type multidrug/protein/lipid transport system, ATPase component [Thermoanaerobacter tengcongensis]). pfam00664,ABC_membrane, ABC transporter transmembrane region. pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative ABC transporter fused permease and ATP-binding protein complement(2862295..2864103) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174219 YP_001223287.1 CDS CMM_2542 NC_009480.1 2864100 2865962 R putative ABC transporter, fused permease and ATP-binding protein (NP_629588.1| putative ABC transporter [Streptomyces coelicolor A3(2)]; CAA89862.1| ABC transporter [Bacillus subtilis]). pfam00664, ABC_membrane,ABC transporter transmembrane region. pfam00005, ABC_tran,ABC transporter.; Specificity unclear; putative ABC transporter fused permease and ATP-binding protein complement(2864100..2865962) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174915 YP_001223288.1 CDS ddaH NC_009480.1 2866540 2867391 R putative NGNG-dimethylarginine dimethylaminohydrolase (Dimethylargininase) (NP_822866.1| putative dimethylarginine dimethylaminohydrolase [Streptomyces avermitilis MA-4680]; ZP_00213107.1| COG1834: N-Dimethylarginine dimethylaminohydrolase [Burkholderia cepacia R18194]). pfam02274, Amidinotransf,Amidinotransferase.; High confidence in function and specificity; putative dimethylarginine dimethylaminohydrolase complement(2866540..2867391) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174883 YP_001223289.1 CDS purH NC_009480.1 2873905 2875530 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(2873905..2875530) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175352 YP_001223290.1 CDS purN NC_009480.1 2875527 2876126 R glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase complement(2875527..2876126) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175699 YP_001223291.1 CDS CMM_2546 NC_009480.1 2876130 2877410 R conserved membrane protein (NP_789039.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; ZP_00293807.1| hypothetical protein Tfus02000005 [Thermobifida fusca]).; hypothetical protein complement(2876130..2877410) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175057 YP_001223292.1 CDS sucD NC_009480.1 2877571 2878458 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(2877571..2878458) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174829 YP_001223293.1 CDS sucC NC_009480.1 2878486 2879649 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(2878486..2879649) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175724 YP_001223294.1 CDS CMM_2549 NC_009480.1 2879897 2880718 D conserved hypothetical protein (EAA63080.1| hypothetical protein AN2678.2 [Aspergillus nidulans FGSC A4]; ZP_00293575.1| COG3662: Uncharacterized protein conserved in bacteria [Thermobifida fusca]).; hypothetical protein 2879897..2880718 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175080 YP_001223295.1 CDS CMM_2550 NC_009480.1 2880821 2882821 D hypothetical protein 2880821..2882821 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175009 YP_001223296.1 CDS uvrD1 NC_009480.1 2882793 2885243 R putative ATP-dependent DNA helicase (ZP_00227575.1| COG0210: Superfamily I DNA and RNA helicases [Kineococcus radiotolerans SRS30216]; NP_628954.1| putative ATP-dependent DNA helicase II [Streptomyces coelicolor A3(2)]). pfam00580, UvrD-helicase, UvrD/REP helicase. The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA.; Specificity unclear; ATP-dependent DNA helicase complement(2882793..2885243) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175077 YP_001223297.1 CDS glpQ1 NC_009480.1 2885343 2886401 R putative glycerophosphoryl diester phosphodiesterase (ZP_00108394.1| COG0584: Glycerophosphoryl diester phosphodiesterase [Nostoc punctiforme]; ZP_00292545.1| COG0584: Glycerophosphoryl diester phosphodiesterase [Thermobifida fusca]). GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE HYDROLYZES DEACYLATED PHOSPHOLIPIDS TO G3P AND THE CORRESPONDING ALCOHOLS. pfam03009, GDPD, Glycerophosphoryl diester phosphodiesterase family.; High confidence in function and specificity; hypothetical protein complement(2885343..2886401) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173222 YP_001223298.1 CDS CMM_2553 NC_009480.1 2886534 2887337 D conserved membrane protein (ZP_00227380.1| COG4760: Predicted membrane protein [Kineococcus radiotolerans SRS30216]; NP_627303.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam06539,DUF1112, Protein of unknown function (DUF1112).; Function unclear; hypothetical protein 2886534..2887337 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175362 YP_001223299.1 CDS guaA NC_009480.1 2887446 2889026 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(2887446..2889026) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175014 YP_001223300.1 CDS CMM_2555 NC_009480.1 2889023 2889565 R conserved membrane protein (NP_789036.1| putative membrane protein [Tropheryma whipplei TW08/27]; NP_601701.1| hypothetical membrane protein [Corynebacterium glutamicum ATCC 13032]).; Conserved hypothetical protein; hypothetical protein complement(2889023..2889565) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174061 YP_001223301.1 CDS CMM_2556 NC_009480.1 2889575 2890582 R conserved membrane protein (NP_789035.1| putative membrane protein [Tropheryma whipplei TW08/27]; ZP_00057673.1| COG3346: Uncharacterized conserved protein [Thermobifida fusca]).; Conserved hypothetical protein; hypothetical protein complement(2889575..2890582) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175837 YP_001223302.1 CDS napA NC_009480.1 2890582 2892102 R putative Na+/H+ exchange transport protein, Cpa2 family (NP_631436.1| putative transmembrane transport protein. [Streptomyces coelicolor A3(2)]; G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis). , InterPro: Na+/H+ exchanger pfam00999, Na_H_Exchanger,Sodium/hydrogen exchanger family. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells.; High confidence in function and specificity; CPA2 family Na+/H+ antiporter complement(2890582..2892102) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174837 YP_001223303.1 CDS CMM_2558 NC_009480.1 2892106 2892639 R conserved hypothetical protein (ZP_00225982.1| COG0490: Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Kineococcus radiotolerans SRS30216]; CAB08338.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam02080, TrkA_C, TrkA-C domain. This domain is often found next to the pfam02254 domain.; Function unclear; hypothetical protein complement(2892106..2892639) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174746 YP_001223304.1 CDS guaB1 NC_009480.1 2892741 2893859 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase complement(2892741..2893859) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175838 YP_001223305.1 CDS CMM_2560 NC_009480.1 2893852 2894952 R hypothetical protein complement(2893852..2894952) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173882 YP_001223306.1 CDS guaB2 NC_009480.1 2895118 2896620 R Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (ZP_00227592.1| COG0516: IMP dehydrogenase/GMP reductase [Kineococcus radiotolerans SRS30216]; NP_826177.1| putative inosine-5'-monophosphate dehydrogenase [Streptomyces avermitilis MA-4680]). pfam00478, IMPDH, IMP dehydrogenase / GMP reductase domain.; High confidence in function and specificity; inosine-5'-monophosphate dehydrogenase complement(2895118..2896620) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174384 YP_001223307.1 CDS livH NC_009480.1 2896858 2898318 D putative branched-chain amino acid ABC transporter,permease component (ZP_00291531.1| COG0559: Branched-chain amino acid ABC-type transport system, permease components [Thermobifida fusca]; NP_682382.1| branched-chain amino acid ABC transporter permease protein [Thermosynechococcus elongatus BP-1]). InterPro: Binding-system dependent bacterial transporters (araH livH/limM families). pfam02653, BPD_transp_2, Branched-chain amino acid transport system / permease component.; High confidence in function and specificity; branched-chain amino acid ABC transporterpermease 2896858..2898318 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175280 YP_001223308.1 CDS livM NC_009480.1 2898325 2899296 D putative branched-chain amino acid ABC transporter,permease component (ZP_00291530.1| COG4177: ABC-type branched-chain amino acid transport system, permease component [Thermobifida fusca]; ZP_00202257.1| COG4177: ABC-type branched-chain amino acid transport system,permease component [Synechococcus elongatus PCC 7942]). pfam02653, BPD_transp_2, Branched-chain amino acid transport system / permease component.; High confidence in function and specificity; putative branched-chain amino acid ABC transporter permease 2898325..2899296 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173123 YP_001223309.1 CDS livG NC_009480.1 2899289 2900212 D putatice branched-chain amino acid ABC transporter,ATPase component (ZP_00291529.1| COG0411: ABC-type branched-chain amino acid transport systems, ATPase component [Thermobifida fusca]; ZP_00202256.1| COG0411: ABC-type branched-chain amino acid transport systems,ATPase component [Synechococcus elongatus PCC 7942]). pfam00005, ABC_tran, ABC transporter.; High confidence in function and specificity; putative branched-chain amino acid ABC transporter ATPase 2899289..2900212 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173705 YP_001223310.1 CDS livF NC_009480.1 2900209 2900967 D putative branched-chain amino acid ABC transporter,ATPase component (ZP_00291528.1| COG0410: ABC-type branched-chain amino acid transport systems, ATPase component [Thermobifida fusca]; NP_680844.1| branched-chain amino acid ABC transporter ATP-binding protein [Thermosynechococcus elongatus BP-1]). pfam00005,ABC_tran, ABC transporter.; High confidence in function and specificity; putative branched-chain amino acid ABC transporter ATPase 2900209..2900967 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174603 YP_001223311.1 CDS livK NC_009480.1 2901299 2902582 R putative branched-chain amino acid ABC transporter,substrate-binding protein (ZP_00291710.1| COG0683: ABC-type branched-chain amino acid transport systems,periplasmic component [Thermobifida fusca]; ZP_00164894.2| COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component [Synechococcus elongatus PCC 7942]). pfam01094, ANF_receptor, Receptor family ligand binding region. This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.; High confidence in function and specificity; putative branched-chain amino acid ABC transporter substrate-binding protein complement(2901299..2902582) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174891 YP_001223312.1 CDS CMM_2567 NC_009480.1 2902761 2903714 R putative permease, DMT family (NP_826050.1| hypothetical protein SAV4873 [Streptomyces avermitilis MA-4680]; AAQ73536.1| RarD [Streptomyces exfoliatus]). InterPro: RarD protein; Specificity unclear; permease DMT family complement(2902761..2903714) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174794 YP_001223313.1 CDS groES NC_009480.1 2903875 2904171 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(2903875..2904171) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174878 YP_001223314.1 CDS CMM_2569 NC_009480.1 2904316 2905518 D putative SAM-dependant methyltransferase (ZP_00190966.2| COG0500: SAM-dependent methyltransferases [Kineococcus radiotolerans SRS30216]; NP_628916.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00058035.1| COG0500: SAM-dependent methyltransferases [Thermobifida fusca]).; Function unclear; putative SAM-dependent methyltransferase 2904316..2905518 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174628 YP_001223315.1 CDS CMM_2570 NC_009480.1 2905604 2906029 R conserved membrane protein (YP_062810.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629794.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; NP_390387.1| yqfX [Bacillus subtilis]).; Function unclear; hypothetical protein complement(2905604..2906029) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174856 YP_001223316.1 CDS CMM_2571 NC_009480.1 2906134 2907753 R putative acetyltransferase/glycoprotease fusion protein (NP_826151.1| putative glycoprotease [Streptomyces avermitilis MA-4680]; NP_628910.1| putative O-sialoglycoprotein endopeptidase [Streptomyces coelicolor A3(2)]). apparently a fusion protein with a C-terminal peptidase domain: InterPro: Glycoprotease (M22) metallo-protease family pfam00814, Peptidase_M22, Glycoprotease family. and a N-terminal acetyltransferase domain: COG0456, RimI, Acetyltransferases [General function prediction only] pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase/glycoprotease fusion protein complement(2906134..2907753) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173835 YP_001223317.1 CDS CMM_2572 NC_009480.1 2907750 2908367 R conserved hypothetical protein (YP_062813.1| hypothetical protein Lxx19930 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058039.1| COG1214: Inactive homolog of metal-dependent proteases, putative molecular chaperone [Thermobifida fusca]; NP_628908.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam00814,Peptidase_M22, Glycoprotease family.; hypothetical protein complement(2907750..2908367) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175048 YP_001223318.1 CDS alrA2 NC_009480.1 2908377 2910077 R putative alanine racemase (YP_062001.1| alanine racemase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826144.1| putative alanine racemase [Streptomyces avermitilis MA-4680]; ZP_00058041.1| COG0787: Alanine racemase [Thermobifida fusca]). fusion protein; N-terminal alanine racemase domain: pfam01168, Ala_racemase_N,Alanine racemase, N-terminal domain + pfam00842,Ala_racemase_C, Alanine racemase, C-terminal domain. and C-terminal ATPase domain: COG0802, COG0802, Predicted ATPase or kinase [General function prediction only], pfam02367,UPF0079, Uncharacterised P-loop hydrolase UPF0079. This uncharacterised family contains a P-loop.; Specificity unclear; putative alanine racemase complement(2908377..2910077) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174730 YP_001223319.1 CDS alrA1 NC_009480.1 2910074 2911231 R putative alanine racemase (YP_062815.1| alanine racemase [Leifsonia xyli subsp. xyli str. CTCB07]; CAB01033.1| ALANINE RACEMASE ALR [Mycobacterium tuberculosis H37Rv]; ZP_00058041.1| COG0787: Alanine racemase [Thermobifida fusca]). pfam01168, Ala_racemase_N,Alanine racemase, N-terminal domain. pfam00842,Ala_racemase_C, Alanine racemase, C-terminal domain. InterPro: Alanine racemase.; High confidence in function and specificity; putative alanine racemase complement(2910074..2911231) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174795 YP_001223320.1 CDS acpS NC_009480.1 2911228 2911587 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(2911228..2911587) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173026 YP_001223321.1 CDS glmS NC_009480.1 2911598 2913448 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(2911598..2913448) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175318 YP_001223322.1 CDS coaA NC_009480.1 2913597 2914556 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 2913597..2914556 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173153 YP_001223323.1 CDS glmM NC_009480.1 2914590 2915903 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(2914590..2915903) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174761 YP_001223324.1 CDS rpsI NC_009480.1 2915927 2916412 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(2915927..2916412) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174838 YP_001223325.1 CDS rplM NC_009480.1 2916463 2916909 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(2916463..2916909) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174726 YP_001223326.1 CDS truA NC_009480.1 2917061 2918065 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(2917061..2918065) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175287 YP_001223327.1 CDS CMM_2582 NC_009480.1 2918062 2919132 R conserved hypothetical protein, putative acetyltransferase (CAF21237.1| GCN5-related N-acetyltransferase [Corynebacterium glutamicum ATCC 13032]; NP_628328.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase complement(2918062..2919132) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175650 YP_001223328.1 CDS rplQ NC_009480.1 2919257 2919820 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(2919257..2919820) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175354 YP_001223329.1 CDS rpoA NC_009480.1 2919873 2920868 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(2919873..2920868) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173499 YP_001223330.1 CDS rpsK NC_009480.1 2921030 2921428 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(2921030..2921428) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174340 YP_001223331.1 CDS rpsM NC_009480.1 2921473 2921847 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(2921473..2921847) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173081 YP_001223332.1 CDS rpmJ NC_009480.1 2922001 2922114 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(2922001..2922114) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175361 YP_001223333.1 CDS infA NC_009480.1 2922187 2922408 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(2922187..2922408) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174797 YP_001223334.1 CDS mtlD NC_009480.1 2922650 2923819 R putative mannitol-1-phosphate 5-dehydrogenase (YP_061273.1| mannitol-1-phosphate 5-dehydrogenase [Leifsonia xyli subsp. xyli str. CTCB07]; AAL89587.1| mannitol-1-phosphate dehydrogenase [Aspergillus niger]). pfam01232, Mannitol_dh, Mannitol dehydrogenase.; High confidence in function and specificity; mannitol-1-phosphate 5-dehydrogenase complement(2922650..2923819) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175980 YP_001223335.1 CDS mtlF NC_009480.1 2923816 2924253 R putative PTS system mannitol-specific IIA component (Mannitol- permease IIA component) (YP_061274.1| PTS system, mannitol-specific enzyme II, A component [Leifsonia xyli subsp. xyli str. CTCB07]; NP_244719.1| PTS system, mannitol-specific enzyme II, A component [Bacillus halodurans C-125]). pfam00359, PTS_EIIA_2,Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. InterPro: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.; Specificity unclear; putative PTS system mannitol-specific IIA component complement(2923816..2924253) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174224 YP_001223336.1 CDS mtlA NC_009480.1 2924361 2925890 R putative PTS system mannitol-specific IIBC component (Mannitol- permease IIBC component) (YP_061275.1| PTS system, mannitol-specific IIBC component [Leifsonia xyli subsp. xyli str. CTCB07]; YP_090154.1| MtlA [Bacillus licheniformis DSM 13]). pfam02378,PTS_EIIC, Phosphotransferase system, EIIC. pfam02302,PTS_IIB, PTS system, Lactose/Cellobiose specific IIB subunit.; Specificity unclear; putative PTS system mannitol-specific IIBC component complement(2924361..2925890) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174667 YP_001223337.1 CDS CMM_2592 NC_009480.1 2926003 2927673 R phosphoenolpyruvate-protein phosphotransferase, PTS enzyme I (YP_061276.1| PTS system, enzyme I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_828150.1| putative phosphoenolpyruvate-protein phosphotransferase [Streptomyces avermitilis MA-4680]). pfam05524, PEP-utilisers_N, PEP-utilising enzyme, N-terminal. pfam02896,PEP-utilizers_C, PEP-utilising enzyme, TIM barrel domain. pfam00391, PEP-utilizers, PEP-utilising enzyme, mobile domain. InterPro: PEP-utilizing enzyme.; Specificity unclear; phosphoenolpyruvate-protein phosphotransferase,PTS enzyme I complement(2926003..2927673) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174038 YP_001223338.1 CDS CMM_2593 NC_009480.1 2927670 2927936 R phosphotransferase system, HPr-related protein (YP_061277.1| phosphocarrier protein HPr [Leifsonia xyli subsp. xyli str. CTCB07]; NP_623408.1| Phosphotransferase system, HPr-related proteins [Thermoanaerobacter tengcongensis]). pfam00381, PTS-HPr, PTS HPr component phosphorylation site.; Specificity unclear; hypothetical protein complement(2927670..2927936) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173888 YP_001223339.1 CDS CMM_2594 NC_009480.1 2928035 2928415 R putative PTS system cellobiose-specific IIB component (Cellobiose- permease IIB component) (ZP_00322547.1| COG1440: Phosphotransferase system cellobiose-specific component IIB [Pediococcus pentosaceus ATCC 25745]; YP_061278.1| PTS system, IIB component [Leifsonia xyli subsp. xyli str. CTCB07]). pfam02302,PTS_IIB, PTS system, Lactose/Cellobiose specific IIB subunit.; Specificity unclear; putative PTS system cellobiose-specific IIB component complement(2928035..2928415) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174642 YP_001223340.1 CDS CMM_2595 NC_009480.1 2928627 2930615 D putative transcription antiterminator containing a PTS domain (YP_061280.1| transcription antiterminator,BglG family [Leifsonia xyli subsp. xyli str. CTCB07]; YP_074779.1| transcription antiterminator BglG family [Symbiobacterium thermophilum IAM 14863]). pfam00874, PRD,PRD domain. The PRD domain (for PTS Regulation Domain), is the phosphorylatable regulatory domain found in bacterial transcriptional antiterminator of the BglG family as well as in activators such as MtlR and LevR. pfam00359,PTS_EIIA_2, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. InterPro: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.; Specificity unclear; transcription antiterminator 2928627..2930615 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175825 YP_001223341.1 CDS mapA2 NC_009480.1 2930668 2931504 R putative methionine aminopeptidase, family M24A (Peptidase M) (YP_062833.1| methionine aminopeptidase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227085.1| COG0024: Methionine aminopeptidase [Kineococcus radiotolerans SRS30216]; NP_826125.1| putative methionine aminopeptidase [Streptomyces avermitilis MA-4680]). pfam00557, Peptidase_M24, metallopeptidase family M24. InterPro: Methionine aminopeptidase subfamily 1.; High confidence in function and specificity; putative methionine aminopeptidase complement(2930668..2931504) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175752 YP_001223342.1 CDS adk NC_009480.1 2931509 2932111 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(2931509..2932111) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175264 YP_001223343.1 CDS secY NC_009480.1 2932108 2933430 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(2932108..2933430) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173069 YP_001223344.1 CDS rplO NC_009480.1 2933556 2934134 R late assembly protein; 50S ribosomal protein L15 complement(2933556..2934134) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173274 YP_001223345.1 CDS rpmD NC_009480.1 2934134 2934316 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(2934134..2934316) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173427 YP_001223346.1 CDS rpsE NC_009480.1 2934316 2934981 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(2934316..2934981) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173805 YP_001223347.1 CDS rplR NC_009480.1 2935017 2935388 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(2935017..2935388) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175741 YP_001223348.1 CDS rplF NC_009480.1 2935391 2935927 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(2935391..2935927) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173836 YP_001223349.1 CDS rpsH NC_009480.1 2935932 2936330 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(2935932..2936330) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173700 YP_001223350.1 CDS rplE NC_009480.1 2936468 2937064 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(2936468..2937064) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175075 YP_001223351.1 CDS rplX NC_009480.1 2937067 2937426 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(2937067..2937426) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174553 YP_001223352.1 CDS rplN NC_009480.1 2937429 2937797 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(2937429..2937797) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173571 YP_001223353.1 CDS rpsQ NC_009480.1 2937825 2938121 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(2937825..2938121) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175408 YP_001223354.1 CDS rpmC NC_009480.1 2938124 2938450 R 50S ribosomal protein L29 (YP_062846.1| 50S ribosomal protein L29 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789155.1| 50s ribosomal protein L29 [Tropheryma whipplei TW08/27]). pfam00831, Ribosomal_L29,Ribosomal L29 protein. InterPro: Ribosomal protein L29.; High confidence in function and specificity; 50S ribosomal protein L29 complement(2938124..2938450) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173398 YP_001223355.1 CDS rplP NC_009480.1 2938450 2938869 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(2938450..2938869) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175071 YP_001223356.1 CDS rpsC NC_009480.1 2938872 2939669 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(2938872..2939669) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173113 YP_001223357.1 CDS rplV NC_009480.1 2939669 2940061 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(2939669..2940061) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173009 YP_001223358.1 CDS rpsS NC_009480.1 2940087 2940368 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(2940087..2940368) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174210 YP_001223359.1 CDS rplB NC_009480.1 2940381 2941220 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(2940381..2941220) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174211 YP_001223360.1 CDS rplW NC_009480.1 2941243 2941542 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(2941243..2941542) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173292 YP_001223361.1 CDS rplD NC_009480.1 2941539 2942195 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(2941539..2942195) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174526 YP_001223362.1 CDS rplC NC_009480.1 2942198 2942851 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(2942198..2942851) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174925 YP_001223363.1 CDS rpsJ NC_009480.1 2942860 2943168 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(2942860..2943168) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173021 YP_001223364.1 CDS CMM_2619 NC_009480.1 2943609 2944577 R putative topoisomerase IB (NP_962178.1| hypothetical protein MAP3244 [Mycobacterium avium subsp. paratuberculosis str. k10]; YP_119639.1| hypothetical protein nfa34270 [Nocardia farcinica IFM 10152]; ZP_00195032.2| COG3569: Topoisomerase IB [Mesorhizobium sp. BNC1]). pfam01028, Topoisom_I, Eukaryotic DNA topoisomerase I, catalytic core. Topoisomerase I promotes the relaxation of DNA superhelical tension by introducing a transient single-stranded break in duplex DNA and are vital for the processes of replication, transcription, and recombination.; Function unclear; putative topoisomerase IB complement(2943609..2944577) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173782 YP_001223365.1 CDS tufA NC_009480.1 2944727 2945920 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(2944727..2945920) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175645 YP_001223366.1 CDS fusA NC_009480.1 2946034 2948148 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(2946034..2948148) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175233 YP_001223367.1 CDS rpsG NC_009480.1 2948196 2948666 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(2948196..2948666) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174475 YP_001223368.1 CDS rpsL NC_009480.1 2948666 2949040 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(2948666..2949040) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174347 YP_001223369.1 CDS CMM_2624 NC_009480.1 2949306 2949731 R hypothetical membrane protein (YP_062863.1| hypothetical protein Lxx20430 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(2949306..2949731) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174985 YP_001223370.1 CDS CMM_2625 NC_009480.1 2949751 2950743 R hypothetical membrane protein (YP_062864.1| hypothetical protein Lxx20440 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(2949751..2950743) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175094 YP_001223371.1 CDS CMM_2626 NC_009480.1 2950817 2951656 R putative polar amino acid ABC transporter, ATP-binding protein (P39456|YCKI_BACSU Probable amino-acid ABC transporter ATP-binding protein yckI; YP_088467.1| GlnQ protein [Mannheimia succiniciproducens MBEL55E]).; Specificity unclear; putative polar amino acid ABC transporter ATP-binding protein complement(2950817..2951656) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174439 YP_001223372.1 CDS CMM_2627 NC_009480.1 2951643 2952308 R putative polar amino acid ABC transporter, permease component (ZP_00235846.1| amino acid ABC transporter,permease protein [Bacillus cereus G9241]; NP_283777.1| putative amino acid permease integral membrane protein [Neisseria meningitidis Z2491]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative polar amino acid ABC transporterpermease complement(2951643..2952308) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174875 YP_001223373.1 CDS CMM_2628 NC_009480.1 2952353 2953201 R putative polar amino acid ABC transporter,substrate-binding protein (ZP_00332407.1| COG0834: ABC-type amino acid transport/signal transduction systems,periplasmic component/domain [Streptococcus suis 89/1591]; NP_349917.1| Periplasmic amino acid binding protein [Clostridium acetobutylicum ATCC 824]). pfam00497,SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3. InterPro: Bacterial extracellular solute-binding proteins family 3.; Specificity unclear; putative polar amino acid ABC transportersubstrate-binding protein complement(2952353..2953201) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174540 YP_001223374.1 CDS CMM_2629 NC_009480.1 2953410 2953895 R hypothetical protein complement(2953410..2953895) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174480 YP_001223375.1 CDS rpoC NC_009480.1 2954078 2957977 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(2954078..2957977) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174881 YP_001223376.1 CDS rpoB NC_009480.1 2958026 2961514 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(2958026..2961514) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174810 YP_001223377.1 CDS CMM_2632 NC_009480.1 2961820 2962488 D putative Zn-dependant hydrolase (ZP_00291971.1| COG0491: Zn-dependent hydrolases, including glyoxylases [Thermobifida fusca]; NP_626224.1| putative hydrolase [Streptomyces coelicolor A3(2)]). pfam00753, Lactamase_B,Metallo-beta-lactamase superfamily. InterPro: Metallo-beta-lactamase superfamily.; Hypothetical protein; putative Zn-dependent hydrolase 2961820..2962488 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173071 YP_001223378.1 CDS CMM_2633 NC_009480.1 2962541 2963398 D conserved hypothetical protein (YP_062875.1| hypothetical protein Lxx20650 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625605.1| hypothetical protein SCO1320 [Streptomyces coelicolor A3(2)]). only weak similarity to: pfam01564, Spermine_synth, Spermine/spermidine synthase.; hypothetical protein 2962541..2963398 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174451 YP_001223379.1 CDS CMM_2634 NC_009480.1 2963439 2964623 D conserved hypothetical protein (ZP_00293383.1| COG2133: Glucose/sorbosone dehydrogenases [Thermobifida fusca]; NP_823913.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]).; Function unclear; hypothetical protein 2963439..2964623 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174304 YP_001223380.1 CDS CMM_2635 NC_009480.1 2964688 2965164 D hypothetical protein (YP_062878.1| hypothetical protein Lxx20680 [Leifsonia xyli subsp. xyli str. CTCB07]; D83991 hypothetical protein BH2732 [imported] -Bacillus halodurans (strain C-125)).; hypothetical protein 2964688..2965164 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173454 YP_001223381.1 CDS CMM_2636 NC_009480.1 2965201 2965713 D conserved hypothetical protein (YP_062877.1| phage-related protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228460.2| COG3091: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). weak similarity to: pfam03926, DUF335, Putative metallopeptidase (SprT family). This family of uncharacterised proteins may be zinc metallopeptidases.; hypothetical protein 2965201..2965713 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173096 YP_001223382.1 CDS CMM_2637 NC_009480.1 2965710 2966387 D conserved hypothetical protein (YP_062876.1| hypothetical protein Lxx20660 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628753.1| hypothetical protein SCO4591 [Streptomyces coelicolor A3(2)]). pfam07336, DUF1470,Protein of unknown function (DUF1470). This family consists of several hypothetical bacterial proteins of around 180 residues in length.; hypothetical protein 2965710..2966387 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175274 YP_001223383.1 CDS CMM_2638 NC_009480.1 2966416 2966718 R conserved hypothetical protein (ZP_00358905.1| COG2343: Uncharacterized protein conserved in bacteria [Chloroflexus aurantiacus]; NP_924913.1| hypothetical protein gsl1967 [Gloeobacter violaceus PCC 7421]). pfam04248, DUF427, Domain of unknown function (DUF427).; hypothetical protein complement(2966416..2966718) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173556 YP_001223384.1 CDS CMM_2639 NC_009480.1 2966832 2967422 R hypothetical protein (YP_062880.1| hypothetical protein Lxx20740 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(2966832..2967422) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175552 YP_001223385.1 CDS CMM_2640 NC_009480.1 2967406 2967906 R conserved hypothetical protein (Q98GR7|YW06_RHILO Hypothetical UPF0310 protein msl3206; BAA06500.1| hypothetical protein [Bacillus licheniformis]). pfam01878,DUF55, Protein of unknown function DUF55. This family of proteins have no known function.; hypothetical protein complement(2967406..2967906) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174029 YP_001223386.1 CDS CMM_2641 NC_009480.1 2967976 2968512 D hypothetical protein 2967976..2968512 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175798 YP_001223387.1 CDS CMM_2642 NC_009480.1 2968514 2969041 R hypothetical protein complement(2968514..2969041) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174187 YP_001223388.1 CDS CMM_2643 NC_009480.1 2969091 2969738 D conserved hypothetical protein (YP_062881.1| hypothetical protein Lxx20760 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227854.1| COG3358: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; ZP_00117067.1| COG3358: Uncharacterized conserved protein [Cytophaga hutchinsonii]).; hypothetical protein 2969091..2969738 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173868 YP_001223389.1 CDS CMM_2644 NC_009480.1 2969846 2971516 D putative ATP-dependent helicase (NP_960415.1| hypothetical protein MAP1481c [Mycobacterium avium subsp. paratuberculosis str. k10]; YP_062883.1| ATP-dependent RNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00270, DEAD, DEAD/DEAH box helicase. pfam00271,Helicase_C, Helicase conserved C-terminal domain.; Family membership; putative ATP-dependent helicase 2969846..2971516 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173290 YP_001223390.1 CDS CMM_2645 NC_009480.1 2971696 2972319 D putative transcriptional regulator, TetR family (ZP_00192174.3| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_792961.1| transcriptional regulator, TetR family [Pseudomonas syringae pv. tomato str. DC3000]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 2971696..2972319 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174981 YP_001223391.1 CDS CMM_2646 NC_009480.1 2972390 2972944 R conserved hypothetical protein (YP_062885.1| hypothetical protein Lxx20800 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00049868.1| COG1051: ADP-ribose pyrophosphatase [Magnetospirillum magnetotacticum MS-1]). pfam00293, NUDIX, NUDIX domain.; Family membership; hypothetical protein complement(2972390..2972944) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174996 YP_001223392.1 CDS CMM_2647 NC_009480.1 2973111 2973752 D conserved hypothetical protein, putative phospholipase/carboxylesterase (YP_062886.1| hypothetical protein Lxx20810 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00121273.2| COG0400: Predicted esterase [Bifidobacterium longum DJO10A]). pfam02230,Abhydrolase_2, Phospholipase/Carboxylesterase. This family consists of both phospholipases and carboxylesterases with broad substrate specificity. InterPro: Phospholipase/Carboxylesterase.; Family membership; putative phospholipase/carboxylesterase 2973111..2973752 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175431 YP_001223393.1 CDS CMM_2648 NC_009480.1 2973833 2978653 D putative ATP-dependent helicase (NP_856969.1| PROBABLE ATP-DEPENDENT HELICASE LHR (LARGE HELICASE-RELATED PROTEIN) [Mycobacterium bovis AF2122/97]; NP_600075.2| Lhr-like helicase [Corynebacterium glutamicum ATCC 13032]). pfam00270, DEAD, DEAD/DEAH box helicase. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Function unclear; putative ATP-dependent helicase 2973833..2978653 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175943 YP_001223394.1 CDS CMM_2649 NC_009480.1 2978681 2979484 D putative endonuclease VIII/DNA glycosylase (YP_062887.1| DNA glycosylase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_117186.1| putative endonuclease VIII [Nocardia farcinica IFM 10152]). pfam01149,Fapy_DNA_glyco, Formamidopyrimidine-DNA glycosylase N-terminal domain. pfam06831, H2TH, Formamidopyrimidine-DNA glycosylase H2TH domain. Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidised purines from damaged DNA.; Function unclear; putative endonuclease VIII/DNA glycosylase 2978681..2979484 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175637 YP_001223395.1 CDS CMM_2650 NC_009480.1 2979603 2981135 R putative cationic amino acid permease, APC family (YP_121066.1| putative transporter permease [Nocardia farcinica IFM 10152]; NP_696717.1| possible cationic amino acid transporter [Bifidobacterium longum NCC2705]). pfam00324, AA_permease, Amino acid permease.; Specificity unclear; cationic amino acid permease APC family complement(2979603..2981135) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174862 YP_001223396.1 CDS sigF NC_009480.1 2981390 2982397 D putative RNA polymerase sigma factor, SigF-homolog (stress response/stationary phase sigma factor) (YP_116363.1| putative sigma factor [Nocardia farcinica IFM 10152]; BAC55891.1| RNA polymerase sigma factor [Streptomyces griseus subsp. griseus]). pfam04542,Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. pfam04539,Sigma70_r3, Sigma-70 region 3. pfam04545, Sigma70_r4,Sigma-70, region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. InterPro: Sigma-70 factor family.; Specificity unclear; putative RNA polymerase sigma factor SigF 2981390..2982397 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174495 YP_001223397.1 CDS CMM_2652 NC_009480.1 2982466 2983068 R putative two-component system, sensor kinase/response regulator hybrid protein (NP_631472.1| conserved hypothetical protein SC6D11.19c. [Streptomyces coelicolor A3(2)]; ZP_00226918.1| COG2203: FOG: GAF domain [Kineococcus radiotolerans SRS30216]). pfam03861,ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins.; Family membership; putative two-component system, sensor kinase/response regulator hybrid protein complement(2982466..2983068) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174326 YP_001223398.1 CDS CMM_2653 NC_009480.1 2983279 2984091 R hypothetical protein complement(2983279..2984091) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175563 YP_001223399.1 CDS CMM_2654 NC_009480.1 2984215 2984622 D hypothetical protein (NP_894767.1| possible GRAM domain [Prochlorococcus marinus str. MIT 9313]; NP_638722.1| hypothetical protein XCC3376 [Xanthomonas campestris pv. campestris str. ATCC 33913]).; hypothetical protein 2984215..2984622 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173914 YP_001223400.1 CDS CMM_2655 NC_009480.1 2984687 2984869 D putative transcriptional regulator (NP_824532.1| hypothetical protein SAV3356 [Streptomyces avermitilis MA-4680]; ZP_00226779.1| COG1983: Putative stress-responsive transcriptional regulator [Kineococcus radiotolerans SRS30216]). pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator.; Function unclear; putative transcriptional regulator 2984687..2984869 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173498 YP_001223401.1 CDS CMM_2656 NC_009480.1 2984985 2986892 D putative amidase (NP_831822.1| Glutamyl-tRNA(Gln) amidotransferase subunit A [Bacillus cereus ATCC 14579]; NP_630436.1| putative secreted amidase [Streptomyces coelicolor A3(2)]). pfam01425, Amidase, Amidase.; Family membership; putative amidase 2984985..2986892 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174655 YP_001223402.1 CDS CMM_2657 NC_009480.1 2986913 2988430 R conserved hypothetical protein, putative phosphatase (NP_695256.1| hypothetical secreted protein with probable acid phosphatase domain [Bifidobacterium longum NCC2705]; YP_050157.1| putative phosphatase [Erwinia carotovora subsp. atroseptica SCRI1043]).; Family membership; putative phosphatase complement(2986913..2988430) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174958 YP_001223403.1 CDS CMM_2658 NC_009480.1 2988519 2989901 R putative penicillin-binding protein (ZP_00244789.1| COG1680: Beta-lactamase class C and other penicillin binding proteins [Rubrivivax gelatinosus PM1]; ZP_00109292.1| COG1680: Beta-lactamase class C and other penicillin binding proteins [Nostoc punctiforme PCC 73102]). pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and pfam00768 D-alanyl-D-alanine carboxypeptidase.; Specificity unclear; putative penicillin-binding protein complement(2988519..2989901) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173734 YP_001223404.1 CDS CMM_2659 NC_009480.1 2989898 2990410 R putative transcriptional regulator, MarR-family (ZP_00188603.2| COG1846: Transcriptional regulators [Rubrobacter xylanophilus DSM 9941]; YP_118181.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]). pfam01047, MarR, MarR family.; Specificity unclear; MarR family transcriptional regulator complement(2989898..2990410) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173160 YP_001223405.1 CDS CMM_2660 NC_009480.1 2990469 2991677 D putative monooxygenase (NP_641998.1| oxidoreductase [Xanthomonas axonopodis pv. citri str. 306]; NP_052574.1| oxidoreductase protein homolog Oxi [Corynebacterium glutamicum]). pfam01494, FAD_binding_3, FAD binding domain. pfam01360, Monooxygenase, Monooxygenase. This family includes diverse enzymes that utilise FAD. InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase); Function unclear; putative monooxygenase 2990469..2991677 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173675 YP_001223406.1 CDS CMM_2661 NC_009480.1 2991847 2992254 D Hypothetical protein; hypothetical protein 2991847..2992254 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173118 YP_001223407.1 CDS CMM_2662 NC_009480.1 2992321 2992926 R conserved hypothetical protein, putative nitroreductase (YP_104321.1| nitroreductase family protein [Burkholderia mallei ATCC 23344]; ZP_00310829.1| COG0778: Nitroreductase [Cytophaga hutchinsonii]). pfam00881,Nitroreductase, Nitroreductase family. Members of this family utilise FMN as a cofactor. InterPro: Nitroreductase family.; Function unclear; putative nitroreductase complement(2992321..2992926) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174528 YP_001223408.1 CDS CMM_2663 NC_009480.1 2993046 2994182 R putative oxidoreductase (P55609|Y4OX_RHISN HYPOTHETICAL 39.9 KD PROTEIN Y4OX; NP_437577.1| putative exported oxidoreductase protein [Sinorhizobium meliloti 1021]). pfam01408, GFO_IDH_MocA, Oxidoreductase family,NAD-binding Rossmann fold. pfam02894, GFO_IDH_MocA_C,Oxidoreductase family, C-terminal alpha/beta domain. InterPro: Oxidoreductase N-terminal.; Function unclear; putative oxidoreductase complement(2993046..2994182) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174392 YP_001223409.1 CDS CMM_2664 NC_009480.1 2994179 2994910 R conserved hypothetical protein (YP_061429.1| ThuA protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00354380.1| COG4813: Trehalose utilization protein [Kineococcus radiotolerans SRS30216]). pfam06283, DUF1037,Protein of unknown function (DUF1037).; Function unclear; hypothetical protein complement(2994179..2994910) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173759 YP_001223410.1 CDS CMM_2665 NC_009480.1 2995087 2995941 D conserved hypothetical protein (NP_870739.1| hypothetical protein RB12844 [Rhodopirellula baltica SH 1]; ZP_00316033.1| hypothetical protein Mdeg02002771 [Microbulbifer degradans 2-40]).; hypothetical protein 2995087..2995941 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174144 YP_001223411.1 CDS CMM_2666 NC_009480.1 2995954 2997852 R putative multidrug ABC transporter, fused permease and ATP-binding protein (NP_828394.1| putative ABC-transport protein [Streptomyces avermitilis MA-4680]; ZP_00294356.1| COG1132: ABC-type multidrug transport system, ATPase and permease components [Thermobifida fusca]). pfam00664, ABC_membrane, ABC transporter transmembrane region. pfam00005, ABC_tran, ABC transporter. InterPro: ABC transporter transmembrane region.; Specificity unclear; putative multidrug ABC transporter fused permease and ATP-binding protein complement(2995954..2997852) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173968 YP_001223412.1 CDS CMM_2667 NC_009480.1 2998206 2999030 D conserved hypothetical protein (NP_627919.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00310497.1| hypothetical protein Chut02000054 [Cytophaga hutchinsonii]). cd01045, Ferritin_like_AB,Ferritin-like domain found in Archaea and Bacteria (Ferritin_like_AB) is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins.; hypothetical protein 2998206..2999030 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175371 YP_001223413.1 CDS CMM_2668 NC_009480.1 2999145 2999423 R conserved membrane protein (YP_056449.1| hypothetical protein PPA1762 [Propionibacterium acnes KPA171202]; NP_879781.1| putative membrane protein [Bordetella pertussis Tohama I]).; Conserved hypothetical protein; hypothetical protein complement(2999145..2999423) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174657 YP_001223414.1 CDS CMM_2669 NC_009480.1 2999548 3000216 D putative two-component system response regulator (YP_004956.1| transcriptional regulatory protein [Thermus thermophilus HB27]; NP_835072.1| Two-component response regulator yhcZ [Bacillus cereus ATCC 14579]). pfam00072,Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. pfam00196, GerE,Bacterial regulatory proteins, luxR family. InterPro: Response regulator receiver domain.; Specificity unclear; putative two-component system response regulator 2999548..3000216 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175331 YP_001223415.1 CDS CMM_2670 NC_009480.1 3000417 3001199 R conserved hypothetical protein, putative cell filamentation protein (NP_298946.1| cell filamentation protein [Xylella fastidiosa 9a5c]; ZP_00133651.2| COG2184: Protein involved in cell division [Haemophilus somnus 2336]). pfam02661, Fic, Fic protein family. This family consists of the Fic (filamentation induced by cAMP) protein and its relatives.; Function unclear; putative cell filamentation protein complement(3000417..3001199) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175857 YP_001223416.1 CDS CMM_2671 NC_009480.1 3001199 3001405 R hypothetical protein complement(3001199..3001405) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174860 YP_001223417.1 CDS CMM_2672 NC_009480.1 3001534 3002652 D putative antibiotic immunity protein, peptidase family S66 (NP_827455.1| hypothetical protein SAV6279 [Streptomyces avermitilis MA-4680]; NP_694083.1| microcin immunity protein [Oceanobacillus iheyensis HTE831]).; Specificity unclear; antibiotic immunity protein peptidase family S66 protein 3001534..3002652 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173058 YP_001223418.1 CDS CMM_2673 NC_009480.1 3003259 3004305 D conserved hypothetical protein (NP_931545.1| hypothetical protein [Photorhabdus luminescens subsp. laumondii TTO1]; NP_416276.2| hypothetical protein b1762 [Escherichia coli K12]).; hypothetical protein 3003259..3004305 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174815 YP_001223419.1 CDS CMM_2674 NC_009480.1 3004315 3005382 R putative glycosyl transferase (YP_119472.1| putative glycosyltransferase [Nocardia farcinica IFM 10152]; ZP_00058346.1| COG0859: ADP-heptose:LPS heptosyltransferase [Thermobifida fusca]). pfam01075,Glyco_transf_9, Glycosyltransferase family 9 (heptosyltransferase).; Function unclear; putative glycosyl transferase complement(3004315..3005382) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173252 YP_001223420.1 CDS CMM_2675 NC_009480.1 3005450 3006115 R conserved membrane protein (NP_626607.1| putative membrane protein [Streptomyces coelicolor A3(2)]; NP_600078.1| hypothetical membrane-associated protein [Corynebacterium glutamicum ATCC 13032]). pfam00597, DedA,DedA family. Members of this family are not functionally characterised. These proteins contain multiple predicted transmembrane regions.; Function unclear; hypothetical protein complement(3005450..3006115) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174443 YP_001223421.1 CDS blaC NC_009480.1 3006326 3007294 D putative beta-lactamase type I precursor (S03167 beta-lactamase (EC 3.5.2.6) precursor - Bacillus cereus; BAD05863.1| beta-lactamase [Streptomyces albulus]). pfam00144, Beta-lactamase, Beta-lactamase. InterPro: Beta-lactamase family.; High confidence in function and specificity; putative beta-lactamase 3006326..3007294 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174575 YP_001223422.1 CDS CMM_2677 NC_009480.1 3007331 3007954 R putative transcriptional regulator, TetR-family (YP_076084.1| TetR family transcriptional regulator [Symbiobacterium thermophilum IAM 14863]; CAA17330.1| POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) [Mycobacterium tuberculosis H37Rv]; NP_827280.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator complement(3007331..3007954) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173791 YP_001223423.1 CDS CMM_2678 NC_009480.1 3008020 3008658 D putative acetyltransferase (NP_600742.1| histone acetyltransferase HPA2 and related acetyltransferases [Corynebacterium glutamicum ATCC 13032]; CAB07039.1| PROBABLE ACETYLTRANSFERASE [Mycobacterium tuberculosis H37Rv]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 3008020..3008658 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175101 YP_001223424.1 CDS CMM_2679 NC_009480.1 3008701 3008937 R hypothetical protein complement(3008701..3008937) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173921 YP_001223425.1 CDS CMM_2680 NC_009480.1 3008983 3009453 D putative transcriptional regulator, MarR family (ZP_00227991.1| COG1846: Transcriptional regulators [Kineococcus radiotolerans SRS30216]; ZP_00058332.1| COG1846: Transcriptional regulators [Thermobifida fusca]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 3008983..3009453 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174113 YP_001223426.1 CDS CMM_2681 NC_009480.1 3009517 3010362 D conserved hypothetical protein, putative hydrolase (NP_737707.1| hypothetical protein CE1097 [Corynebacterium efficiens YS-314]; NP_822654.1| hypothetical protein SAV1479 [Streptomyces avermitilis MA-4680]). pfam03372,Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling.; putative hydrolase 3009517..3010362 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175176 YP_001223427.1 CDS CMM_2682 NC_009480.1 3010356 3011033 D hypothetical membrane protein (NP_737708.1| hypothetical protein CE1098 [Corynebacterium efficiens YS-314]; ZP_00198909.1| hypothetical protein Krad07002970 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 3010356..3011033 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174202 YP_001223428.1 CDS CMM_2683 NC_009480.1 3011123 3012706 D putative bifunctional phosphatase/glycosyl transferase (N-terminal: COG0241, HisB, Histidinol phosphatase and related phosphatases; pfam00702,Hydrolase, haloacid dehalogenase-like hydrolase.; ZP_00056621.1| COG0241: Histidinol phosphatase and related phosphatases [Magnetospirillum magnetotacticum] C-terminal: COG0859, RfaF, ADP-heptose:LPS heptosyltransferase, pfam01075, Glyco_transf_9,Glycosyltransferase family 9 (heptosyltransferase); NP_630286.1| putative transferase [Streptomyces coelicolor A3(2)]; ZP_00058348.1| COG0859: ADP-heptose:LPS heptosyltransferase [Thermobifida fusca]). two domain protein. N-terminal: COG0241, HisB, Histidinol phosphatase and related phosphatases; pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. C-terminal: InterPro: Glycosyltransferase family 9; pfam01075, Glyco_transf_9,Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.; Function unclear; putative bifunctional phosphatase/glycosyl transferase 3011123..3012706 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174363 YP_001223429.1 CDS CMM_2684 NC_009480.1 3012715 3013755 D putative glycosyl transferase (YP_118607.1| hypothetical protein nfa23960 [Nocardia farcinica IFM 10152]; NP_962179.1| hypothetical protein MAP3245 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_630287.1| putative transferase [Streptomyces coelicolor A3(2)]). pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. InterPro: Glycosyl transferases group 1.; Function unclear; putative glycosyl transferase 3012715..3013755 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174466 YP_001223430.1 CDS CMM_2685 NC_009480.1 3013752 3015701 D putative bifunctional glycosyl transferase/isomerase 3013752..3015701 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174777 YP_001223431.1 CDS CMM_2686 NC_009480.1 3015698 3017101 D putative bifunctional ADP-heptose synthase/transferase (NP_630290.1| putative bifunctional synthase/transferase [Streptomyces coelicolor A3(2)]; NP_962186.1| hypothetical protein MAP3252 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00294, PfkB,pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases. pfam01467,CTP_transf_2, Cytidylyltransferase. InterPro: PfkB family of carbohydrate kinases.; Specificity unclear; putative bifunctional ADP-heptose synthase/transferase 3015698..3017101 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174076 YP_001223432.1 CDS CMM_2687 NC_009480.1 3017174 3017878 D putative short-chain dehydrogenase/oxidoreductase (NP_962187.1| hypothetical protein MAP3253 [Mycobacterium avium subsp. paratuberculosis str. k10]; YP_118608.1| putative short chain dehydrogenase [Nocardia farcinica IFM 10152]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Function unclear; putative short-chain dehydrogenase/oxidoreductase 3017174..3017878 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174530 YP_001223433.1 CDS CMM_2688 NC_009480.1 3018382 3019062 R putative acetyl xylan esterase (XP_330314.1| hypothetical protein [Neurospora crassa]; AAC39371.1| acetyl xylan esterase II precursor [Penicillium purpurogenum]). , pfam01083, Cutinase, Cutinase.; Conserved hypothetical protein; hypothetical protein complement(3018382..3019062) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175842 YP_001223434.1 CDS CMM_2689 NC_009480.1 3019687 3020064 R Hypothetical protein; hypothetical protein complement(3019687..3020064) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174257 YP_001223435.1 CDS CMM_2690 NC_009480.1 3020157 3020768 R hypothetical protein (NP_103310.1| hypothetical protein mll1813 [Mesorhizobium loti MAFF303099]).; hypothetical protein complement(3020157..3020768) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174359 YP_001223436.1 CDS CMM_2691 NC_009480.1 3020952 3021953 D putative endoglucanase (NP_436984.1| putative cellulase H precursor protein [Sinorhizobium meliloti 1021]; P16218|GUNH_CLOTM Endoglucanase H precursor (EGH) (Endo-1,4-beta-glucanase)(Cellulase H)). weak similarity to: pfam02156, Glyco_hydro_26, Glycosyl hydrolase family 26.; Specificity unclear; putative endoglucanase 3020952..3021953 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175104 YP_001223437.1 CDS CMM_2692 NC_009480.1 3022066 3023475 D putative endoglucanase (P16218|GUNH_CLOTM Endoglucanase H precursor (EGH) (Endo-1,4-beta-glucanase)(Cellulase H); ZP_00329205.1| COG4124: Beta-mannanase [Moorella thermoacetica ATCC 39073]). , weak similarity to: pfam02156, Glyco_hydro_26, Glycosyl hydrolase family 26.; Specificity unclear; putative endoglucanase 3022066..3023475 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173738 YP_001223438.1 CDS CMM_2693 NC_009480.1 3023600 3024913 D conserved hypothetical protein (YP_062996.1| hypothetical protein Lxx22070 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627950.1| putative secreted protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 3023600..3024913 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174556 YP_001223439.1 CDS CMM_2694 NC_009480.1 3025105 3026142 D conserved hypothetical protein (NP_948299.1| putative DNA-binding protein [Rhodopseudomonas palustris CGA009]; YP_081386.1| Hypothetical Virulence protein RhuM [Bacillus licheniformis DSM 13]).; Family membership; hypothetical protein 3025105..3026142 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173930 YP_001223440.1 CDS CMM_2695 NC_009480.1 3026264 3027400 R putative heptosyltransferase (YP_118610.1| putative glycosyltransferase [Nocardia farcinica IFM 10152]; ZP_00333863.1| COG0859: ADP-heptose:LPS heptosyltransferase [Thiobacillus denitrificans ATCC 25259]). pfam01075, Glyco_transf_9, Glycosyltransferase family 9 (heptosyltransferase).; Function unclear; hypothetical protein complement(3026264..3027400) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175019 YP_001223441.1 CDS CMM_2696 NC_009480.1 3027486 3028577 R putative transcriptional regulator, LacI family (NP_631460.1| putative LacI-family transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_696340.1| probable LacI-type transcriptional regulator [Bifidobacterium longum NCC2705]). pfam00356, LacI,Bacterial regulatory proteins, lacI family. pfam00532,Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; hypothetical protein complement(3027486..3028577) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175861 YP_001223442.1 CDS CMM_2697 NC_009480.1 3028654 3029595 D putative sugar ABC transporter, permease component (NP_822205.1| putative binding-protein dependent transport protein [Streptomyces avermitilis MA-4680]; ZP_00121010.2| COG1175: ABC-type sugar transport systems,permease components [Bifidobacterium longum DJO10A]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 3028654..3029595 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175847 YP_001223443.1 CDS CMM_2698 NC_009480.1 3029598 3030548 D putative sugar ABC transporter, permease component (NP_631458.1| putative binding-protein dependent transport protein. [Streptomyces coelicolor A3(2)]; NP_696338.1| probable permease of ABC transporter system for sugars [Bifidobacterium longum NCC2705]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 3029598..3030548 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175567 YP_001223444.1 CDS CMM_2699 NC_009480.1 3030610 3031965 D putative sugar ABC transporter, substrate-binding protein (NP_631457.1| probable solute-binding lipoprotein. [Streptomyces coelicolor A3(2)]; ZP_00121005.2| COG1653: ABC-type sugar transport system, periplasmic component [Bifidobacterium longum DJO10A]). pfam01547, SBP_bac_1,Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1; Specificity unclear; putative sugar ABC transporter substrate-binding protein 3030610..3031965 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175270 YP_001223445.1 CDS bgaB NC_009480.1 3032047 3033846 D putative beta-galactosidase (BAA21669.1| beta-galactosidase [Bacillus circulans]; AAC45218.1| beta-galactosidase [Arthrobacter sp.]). pfam01301,Glyco_hydro_35, Glycosyl hydrolases family 35.; Specificity unclear; putative beta-galactosidase 3032047..3033846 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173608 YP_001223446.1 CDS CMM_2701 NC_009480.1 3033952 3035502 D putative aldehyde dehydrogenase (YP_120727.1| putative aldehyde dehydrogenase [Nocardia farcinica IFM 10152]; NP_828335.1| putative succinate-semialdehyde dehydrogenase [Streptomyces avermitilis MA-4680]). pfam00171, Aldedh, Aldehyde dehydrogenase family.; Function unclear; hypothetical protein 3033952..3035502 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172925 YP_001223447.1 CDS CMM_2702 NC_009480.1 3035499 3037055 D putative bifunctional sugar kinase/nucleotidyltransferase (P_118622.1| hypothetical protein nfa24110 [Nocardia farcinica IFM 10152]; ZP_00299509.1| COG2870: ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Geobacter metallireducens GS-15]). pfam00294, PfkB, pfkB family carbohydrate kinase. pfam01467, CTP_transf_2,Cytidylyltransferase. InterPro: PfkB family of carbohydrate kinases.; Specificity unclear; putative bifunctional sugar kinase/nucleotidyltransferase 3035499..3037055 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174675 YP_001223448.1 CDS CMM_2703 NC_009480.1 3037145 3037336 D hypothetical protein (YP_118623.1| hypothetical protein nfa24120 [Nocardia farcinica IFM 10152]; NP_487423.1| unknown protein [Nostoc sp. PCC 7120]).; hypothetical protein 3037145..3037336 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175543 YP_001223449.1 CDS CMM_2704 NC_009480.1 3037437 3037766 R hypothetical protein complement(3037437..3037766) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173273 YP_001223450.1 CDS CMM_2705 NC_009480.1 3038021 3038533 D conserved hypothetical protein (ZP_00332567.1| COG3860: Uncharacterized protein conserved in bacteria [Streptococcus suis 89/1591]; NP_972365.1| hypothetical protein TDE1761 [Treponema denticola ATCC 35405]; NP_626931.1| putative secreted protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 3038021..3038533 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174469 YP_001223451.1 CDS CMM_2706 NC_009480.1 3038530 3039546 R conserved hypothetical protein (only weak similarities: AAP74077.1| hypothetical protein PBD2.192 [Rhodococcus erythropolis]; NP_960710.1| hypothetical protein MAP1776c [Mycobacterium avium subsp. paratuberculosis str. k10]).; hypothetical protein complement(3038530..3039546) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173417 YP_001223452.1 CDS CMM_2707 NC_009480.1 3039550 3040071 R hypothetical protein complement(3039550..3040071) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174241 YP_001223453.1 CDS CMM_2708 NC_009480.1 3040244 3040732 R hypothetical protein, putative excisionase (NP_938638.1| Putative excisionase [Corynebacterium diphtheriae NCTC 13129]; AAF76245.1| putative excisionase [Arthrobacter sp. TM1]).; hypothetical protein complement(3040244..3040732) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173283 YP_001223454.1 CDS CMM_2709 NC_009480.1 3040792 3041967 R putative metallopeptidase, family M23 (AAS20161.1| hypothetical protein [Arthrobacter aurescens]; CAD47991.1| hypothetical protein [Arthrobacter nicotinovorans]). pfam01551, Peptidase_M37, Peptidase family M23/M37. Members of this family are zinc metallopeptidases with a range of specificities. InterPro: Peptidase family M23/M37.; Function unclear; M23 family metallopeptidase complement(3040792..3041967) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175411 YP_001223455.1 CDS CMM_2710 NC_009480.1 3041964 3042524 R hypothetical protein (CAD47990.1| hypothetical protein [Arthrobacter nicotinovorans]; CAD47990.1| hypothetical protein [Arthrobacter nicotinovorans]).; hypothetical protein complement(3041964..3042524) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174246 YP_001223456.1 CDS CMM_2711 NC_009480.1 3042524 3043921 R hypothetical protein (CAD47989.1| hypothetical protein [Arthrobacter nicotinovorans]; YP_117040.1| hypothetical protein nfa8310 [Nocardia farcinica IFM 10152]; ZP_00058679.1| COG0455: ATPases involved in chromosome partitioning [Thermobifida fusca]).; Family membership; hypothetical protein complement(3042524..3043921) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172924 YP_001223457.1 CDS CMM_2712 NC_009480.1 3044186 3044797 D hypothetical protein (CAD47988.1| hypothetical protein [Arthrobacter nicotinovorans]; NP_862425.1| MC47 [Micrococcus sp. 28]; NP_826047.1| hypothetical protein SAV4870 [Streptomyces avermitilis MA-4680]).; hypothetical protein 3044186..3044797 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173117 YP_001223458.1 CDS CMM_2713 NC_009480.1 3044822 3045145 D Hypothetical protein; hypothetical protein 3044822..3045145 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175750 YP_001223459.1 CDS CMM_2714 NC_009480.1 3045207 3045968 D conserved hypothetical protein (CAD47986.1| hypothetical protein [Arthrobacter nicotinovorans]; NP_954834.1| hypothetical protein [Gordonia westfalica]).; hypothetical protein 3045207..3045968 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174683 YP_001223460.1 CDS CMM_2715 NC_009480.1 3045970 3047523 D conserved hypothetical protein, weak similarities to congugal transfer proteins like TrbL (CAD47985.1| putative transfer gene complex protein-like protein [Arthrobacter nicotinovorans]; NP_066793.1| transfer gene complex protein-like protein [Rhodococcus equi]). weak similarity to:pfam04610, TrbL, TrbL/VirB6 plasmid conjugal transfer protein, and COG3846, TrbL, Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; hypothetical protein 3045970..3047523 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174239 YP_001223461.1 CDS CMM_2716 NC_009480.1 3047536 3049044 D conserved membrane protein (CAD47984.1| putative integral membrane protein [Arthrobacter nicotinovorans]; NP_696643.1| narrowly conserved hypothetical protein [Bifidobacterium longum NCC2705]).; hypothetical protein 3047536..3049044 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174281 YP_001223462.1 CDS CMM_2717 NC_009480.1 3049099 3050808 D putative ATP-binding protein (CAD47983.1| putative ATP-binding protein [Arthrobacter nicotinovorans]; NP_862419.1| putative ATP-binding protein [Micrococcus sp. 28]).; hypothetical protein 3049099..3050808 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174204 YP_001223463.1 CDS CMM_2718 NC_009480.1 3050805 3052583 D putative congujal transfer protein, coupling protein (traG/VirB4) homolog (CAD47982.1| putative conjugative transfer gene complex protein-like protein [Arthrobacter nicotinovorans]; NP_825686.1| putative traG-family protein [Streptomyces avermitilis MA-4680]). InterPro: TraG protein pfam02534, TRAG, TraG/TraD family. The TraG/TraD family are bacterial conjugation proteins.; Specificity unclear; putative traG-family protein 3050805..3052583 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175229 YP_001223464.1 CDS CMM_2719 NC_009480.1 3052580 3052966 D hypothetical protein (CAD47981.1| hypothetical protein [Arthrobacter nicotinovorans]; ZP_00058175.1| hypothetical protein [Thermobifida fusca]).; hypothetical protein 3052580..3052966 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174703 YP_001223465.1 CDS CMM_2720 NC_009480.1 3052963 3053808 D Hypothetical protein; hypothetical protein 3052963..3053808 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175851 YP_001223466.1 CDS CMM_2721 NC_009480.1 3053831 3055084 R Region start changed from 3055087 to 3055030 (-57 bases); putative protein phosphatase complement(3053831..3055084) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175824 YP_001223467.1 CDS CMM_2722 NC_009480.1 3055238 3056566 R putative serine phosphatase, possible regulator of sigma factor activity (ZP_00175659.2| COG2208: Serine phosphatase RsbU, regulator of sigma subunit [Crocosphaera watsonii WH 8501]; NP_874405.1| Serine phosphatase RsbU [Prochlorococcus marinus subsp. marinus str. CCMP1375]). InterPro: Protein phosphatase 2C domain smart00331,PP2C_SIG, Sigma factor PP2C-like phosphatases; Function unclear; putative serine phosphatase complement(3055238..3056566) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175891 YP_001223468.1 CDS CMM_2723 NC_009480.1 3056566 3056988 R conserved hypothetical protein, putative anti-sigma regulatory factor (NP_737815.1| hypothetical protein [Corynebacterium efficiens YS-314]; NP_681341.1| sigma-B activity negative regulator [Thermosynechococcus elongatus BP-1]).; Function unclear; hypothetical protein complement(3056566..3056988) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175067 YP_001223469.1 CDS CMM_2724 NC_009480.1 3056981 3057319 R putative anti-sigma factor antagonist (NP_737814.1| putative anti-sigma factor antagonist [Corynebacterium efficiens YS-314]; ZP_00357937.1| COG1366: Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) [Chloroflexus aurantiacus]). pfam01740, STAS, STAS domain.; Function unclear; hypothetical protein complement(3056981..3057319) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175597 YP_001223470.1 CDS CMM_2725 NC_009480.1 3057585 3057953 D hypothetical protein 3057585..3057953 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175011 YP_001223471.1 CDS CMM_2726 NC_009480.1 3057950 3058576 R putative phosphoglycerate mutase (NP_822948.1| putative mutase [Streptomyces avermitilis MA-4680]; NP_349622.1| Possible phosphoglycerate mutase [Clostridium acetobutylicum ATCC 824]). pfam00300, PGAM,Phosphoglycerate mutase family.; High confidence in function and specificity; phosphoglycerate mutase complement(3057950..3058576) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174681 YP_001223472.1 CDS CMM_2727 NC_009480.1 3058730 3059692 D Hypothetical protein; hypothetical protein 3058730..3059692 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174947 YP_001223473.1 CDS CMM_2728 NC_009480.1 3059727 3060149 R putative acetyltransferase (ZP_00036563.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Enterococcus faecium]; NP_344795.1| acetyltransferase, GNAT family [Streptococcus pneumoniae TIGR4]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase.; Function unclear; putative acetyltransferase complement(3059727..3060149) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174508 YP_001223474.1 CDS CMM_2729 NC_009480.1 3060249 3061322 D conserved hypothetical protein (NP_825341.1| hypothetical protein SAV4164 [Streptomyces avermitilis MA-4680]; ZP_00119088.1| COG2931: RTX toxins and related Ca2+-binding proteins [Cytophaga hutchinsonii]).; hypothetical protein 3060249..3061322 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174468 YP_001223475.1 CDS CMM_2730 NC_009480.1 3061491 3062450 D putative sugar ABC transporter, permease component (NP_827989.1| putative transport system inner membrane protein [Streptomyces avermitilis MA-4680]; ZP_00228707.1| COG1175: ABC-type sugar transport systems,permease components [Kineococcus radiotolerans SRS30216]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 3061491..3062450 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173884 YP_001223476.1 CDS CMM_2731 NC_009480.1 3062450 3063445 D putative sugar ABC transporter, permease component (ZP_00206070.1| COG0395: ABC-type sugar transport system,permease component [Enterococcus faecium]; NP_242732.1| sugar transport system (permease) (binding protein dependent transporter) [Bacillus halodurans C-125]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter permease 3062450..3063445 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174229 YP_001223477.1 CDS CMM_2732 NC_009480.1 3063473 3063796 R conserved membrane protein, putative exporter, DMT family (AAR04620.1| SugE [Rhodococcus equi]; ZP_00291640.1| COG2076: Membrane transporters of cations and cationic drugs [Thermobifida fusca]). pfam00893,Multi_Drug_Res, Small Multidrug Resistance protein. This family is the Small Multidrug Resistance (SMR) family. InterPro: Integral membrane protein DUF7.; Function unclear; exporter DMT family membrane protein complement(3063473..3063796) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173723 YP_001223478.1 CDS CMM_2733 NC_009480.1 3063923 3065281 R putative sugar ABC transporter, substrate binding protein (BAB18102.1| cyclomaltodextrin binding protein [Thermococcus sp. B1001]; ZP_00110980.2| COG1653: ABC-type sugar transport system, periplasmic component [Nostoc punctiforme PCC 73102]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1.; Specificity unclear; putative sugar ABC transporter substrate binding protein complement(3063923..3065281) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174334 YP_001223479.1 CDS CMM_2734 NC_009480.1 3065381 3066292 R conserved hypothetical protein, putative esterase (NP_102879.1| esterase [Mesorhizobium loti MAFF303099]; NP_765650.1| hypothetical protein SE2095 [Staphylococcus epidermidis ATCC 12228]).; Function unclear; putative esterase complement(3065381..3066292) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174625 YP_001223480.1 CDS glpX NC_009480.1 3066305 3067291 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(3066305..3067291) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174507 YP_001223481.1 CDS CMM_2736 NC_009480.1 3067350 3068483 R conserved membrane protein, AI-E2 family (YP_062564.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_121709.1| hypothetical protein nfa54930 [Nocardia farcinica IFM 10152]). ,pfam01594, UPF0118, Domain of unknown function DUF20. This transmembrane region is found in putative permeases and predicted transmembrane proteins it has no known function. InterPro: Domain of unknown function DUF20.; Conserved hypothetical protein; AI-E2 family membrane protein complement(3067350..3068483) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174610 YP_001223482.1 CDS CMM_2737 NC_009480.1 3068672 3069394 R putative peptide ABC transporter, ATP-binding protein (NP_625651.1| putative ABC transport system ATP-binding protein [Streptomyces coelicolor A3(2)]; NP_601218.1| ABC-type transporter, ATPase component [Corynebacterium glutamicum ATCC 13032]). pfam00005,ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative peptide ABC transporter ATP-binding protein complement(3068672..3069394) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175828 YP_001223483.1 CDS CMM_2738 NC_009480.1 3069391 3070488 R putative peptide ABC transporter, permease component (NP_625652.1| putative ABC transport system transmembrane protein [Streptomyces coelicolor A3(2)]; NP_940625.1| Putative ABC transport system integral membrane protein [Corynebacterium diphtheriae NCTC 13129]). InterPro: DUF214.; Specificity unclear; putative peptide ABC transporter permease complement(3069391..3070488) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175341 YP_001223484.1 CDS CMM_2739 NC_009480.1 3070638 3071813 D putative two component system, sensor kinase (YP_061777.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625653.1| putative two component system histidine kinase [Streptomyces coelicolor A3(2)]). pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal.; Specificity unclear; putative two component system, sensor kinase 3070638..3071813 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175010 YP_001223485.1 CDS CMM_2740 NC_009480.1 3071814 3072434 D putative two-component system, response regulator (CAF20959.1| putative two component response regulator [Corynebacterium glutamicum ATCC 13032]; YP_061776.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00072, Response_reg,Response regulator receiver domain. pfam00196, GerE,Bacterial regulatory proteins, luxR family. InterPro: Response regulator receiver domain.; Specificity unclear; putative two-component system, response regulator 3071814..3072434 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174368 YP_001223486.1 CDS CMM_2741 NC_009480.1 3072689 3073270 R hypothetical protein complement(3072689..3073270) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175723 YP_001223487.1 CDS CMM_2742 NC_009480.1 3073439 3074080 D putative hydrolase (ZP_00291963.1| COG1011: Predicted hydrolase (HAD superfamily) [Thermobifida fusca]; NP_231282.1| hypothetical protein VC1645 [Vibrio cholerae O1 biovar eltor str. N16961]). pfam00702,Hydrolase, haloacid dehalogenase-like hydrolase.; Function unclear; putative hydrolase 3073439..3074080 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175846 YP_001223488.1 CDS CMM_2743 NC_009480.1 3074136 3074864 R conserved hypothetical protein (NP_825805.1| hypothetical protein SAV4628 [Streptomyces avermitilis MA-4680]; YP_120347.1| hypothetical protein nfa41340 [Nocardia farcinica IFM 10152]). pfam01590, GAF, GAF domain. pfam03861, ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. InterPro: GAF domain.; Function unclear; hypothetical protein complement(3074136..3074864) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173945 YP_001223489.1 CDS CMM_2744 NC_009480.1 3074915 3075628 R conserved hypothetical protein (NP_825806.1| hypothetical protein SAV4629 [Streptomyces avermitilis MA-4680]; AAD43816.1| unknown [Rhodococcus rhodochrous]). pfam03861, ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins.; hypothetical protein complement(3074915..3075628) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173682 YP_001223490.1 CDS CMM_2745 NC_009480.1 3076020 3076745 D conserved hypothetical protein, putative F420-dependent NADP reductase (NP_785408.1| hypothetical protein lp_1859 [Lactobacillus plantarum WCFS1]; CAF20864.1| putative secreted protein [Corynebacterium glutamicum ATCC 13032]; ZP_00030268.1| COG2085: Predicted dinucleotide-binding enzymes [Burkholderia fungorum]). pfam03807, F420_oxidored, NADP oxidoreductase coenzyme F420-dependent.; Function unclear; putative F420-dependent NADP reductase 3076020..3076745 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173318 YP_001223491.1 CDS CMM_2746 NC_009480.1 3076755 3077555 D conserved membrane protein, putative permease (ZP_00226048.1| COG0730: Predicted permeases [Kineococcus radiotolerans SRS30216]; NP_746063.1| conserved hypothetical protein [Pseudomonas putida KT2440]). pfam01925, DUF81, Domain of unknown function DUF81. This integral membrane protein family has no known function. InterPro: Domain of unknown function DUF81.; Family membership; putative permease 3076755..3077555 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175893 YP_001223492.1 CDS CMM_2747 NC_009480.1 3077633 3077902 D putative transcriptional regulator, Cro/CI family (NP_640544.1| transcriptional regulator [Xanthomonas axonopodis pv. citri str. 306]; ZP_00193904.3| COG1396: Predicted transcriptional regulators [Mesorhizobium sp. BNC1]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. InterPro: Helix-turn-helix motif.; Specificity unclear; Cro/CI family transcriptional regulator 3077633..3077902 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174744 YP_001223493.1 CDS CMM_2748 NC_009480.1 3077895 3079214 D conserved hypothetical protein, putatively involved in polysaccharide synthesis (P55564|Y4ME_RHISN HYPOTHETICAL 45.7 KD PROTEIN Y4ME; NP_768625.1| HipA protein [Bradyrhizobium japonicum]; ZP_00016645.1| COG3550: Uncharacterized protein related to capsule biosynthesis enzymes [Rhodospirillum rubrum]).; Family membership; hypothetical protein 3077895..3079214 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173517 YP_001223494.1 CDS CMM_2749 NC_009480.1 3079341 3079994 D hypothetical protein 3079341..3079994 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173227 YP_001223495.1 CDS CMM_2750 NC_009480.1 3080032 3080556 D hypothetical protein (YP_118843.1| hypothetical protein nfa26320 [Nocardia farcinica IFM 10152]).; hypothetical protein 3080032..3080556 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174293 YP_001223496.1 CDS kdpA NC_009480.1 3080942 3082618 D catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 3080942..3082618 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175568 YP_001223497.1 CDS kdpB NC_009480.1 3082615 3084765 D putative potassium-transporting ATPase B chain, P-type ATPase (Potassium- translocating ATPase B chain) (YP_054834.1| potassium-transporting ATPase B chain [Propionibacterium acnes KPA171202]; Q9X8Z9|ATKB_STRCO Potassium- transporting ATPase B chain (Potassium-translocating ATPase B chain)). pfam00122, E1-E2_ATPase,E1-E2 ATPase.; High confidence in function and specificity; putative potassium-transporting ATPase B chain,P-type ATPase 3082615..3084765 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174546 YP_001223498.1 CDS kdpC NC_009480.1 3084808 3085416 D putative potassium-transporting ATPase C chain, P-type ATPase (Potassium- translocating ATPase C chain) (YP_054835.1| potassium-transporting ATPase C chain [Propionibacterium acnes KPA171202]; P65212|ATKC_MYCBO Potassium- transporting ATPase C chain (Potassium-translocating ATPase C chain) ). pfam02669, KdpC, K+-transporting ATPase, c chain.; High confidence in function and specificity; putative potassium-transporting ATPase C chain,P-type ATPase 3084808..3085416 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174680 YP_001223499.1 CDS kdpD NC_009480.1 3085448 3087994 D putative two-component system, sensor kinase (YP_054836.1| two-component sensor, KdpD [Propionibacterium acnes KPA171202]; O34971|KDPD_RATRA Sensor protein kdpD; T34823 probable turgor pressure sensor kdpD - Streptomyces coelicolor). MEMBER OF THE TWO-COMPONENT REGULATORY SYSTEM KDPD/KDPE INVOLVED IN THE REGULATION OF THE KDP OPERON. KDPD MAY FUNCTION AS A MEMBRANE-ASSOCIATED PROTEIN KINASE THAT PHOSPHORYLATES KDPE IN RESPONSE TO ENVIRONMENTAL SIGNALS (BY SIMILARITY). pfam02702, KdpD, Osmosensitive K+ channel His kinase sensor domain. pfam00582, Usp, Universal stress protein family. pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Osmosensitive K+ channel His kinase sensor domain.; High confidence in function and specificity; putative two-component system, sensor kinase 3085448..3087994 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174876 YP_001223500.1 CDS kdpE NC_009480.1 3087991 3088695 D putative two-component system, response regulator (YP_054837.1| two-component response regulator, KdpE [Propionibacterium acnes KPA171202]; CAB06852.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN KDPE [Mycobacterium tuberculosis H37Rv]; T34824 probable turgor pressure regulator kdpE - Streptomyces coelicolor). pfam00072,Response_reg, Response regulator receiver domain. pfam00486, Trans_reg_C, Transcriptional regulatory protein, C terminal. InterPro: Response regulator receiver domain.; High confidence in function and specificity; putative two-component system, response regulator 3087991..3088695 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174568 YP_001223501.1 CDS CMM_2756 NC_009480.1 3088749 3089528 D putative esterase/lipase (YP_062928.1| hypothetical protein Lxx21280 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00239215.1| lipase/acylhydrolase, putative [Bacillus cereus G9241]). pfam00657, Lipase_GDSL, GDSL-like Lipase/Acylhydrolase.; Function unclear; putative esterase/lipase 3088749..3089528 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175598 YP_001223502.1 CDS CMM_2757 NC_009480.1 3089570 3089929 D Hypothetical protein; hypothetical protein 3089570..3089929 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175209 YP_001223503.1 CDS CMM_2758 NC_009480.1 3089943 3090152 R hypothetical protein (AC1282 hypothetical protein lmo1659 [imported] - Listeria monocytogenes (strain EGD-e)).; hypothetical protein complement(3089943..3090152) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173011 YP_001223504.1 CDS CMM_2759 NC_009480.1 3090292 3091683 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 3090292..3091683 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174880 YP_001223505.1 CDS CMM_2760 NC_009480.1 3091723 3092037 R putative transcriptional regulator, ArsR family (NP_789021.1| putative regulator [Tropheryma whipplei TW08/27]; NP_301626.1| putative ArsR-family transcriptional regulator [Mycobacterium leprae TN]). pfam01022, HTH_5, Bacterial regulatory protein, arsR family. InterPro: Bacterial regulatory proteins ArsR family.; Specificity unclear; ArsR family transcriptional regulator complement(3091723..3092037) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173638 YP_001223506.1 CDS CMM_2761 NC_009480.1 3092149 3092307 R hypothetical protein complement(3092149..3092307) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173294 YP_001223507.1 CDS CMM_2762 NC_009480.1 3092425 3093090 R conserved hypothetical protein (YP_062932.1| hypothetical protein Lxx21320 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789027.1| putative secreted protein [Tropheryma whipplei TW08/27]).; hypothetical protein complement(3092425..3093090) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174100 YP_001223508.1 CDS CMM_2763 NC_009480.1 3093169 3093711 R catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; N-acetylglutamate synthase complement(3093169..3093711) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173711 YP_001223509.1 CDS CMM_2764 NC_009480.1 3093763 3094035 R Hypothetical protein; hypothetical protein complement(3093763..3094035) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173725 YP_001223510.1 CDS CMM_2765 NC_009480.1 3094037 3095713 R putative two-component system, sensor kinase (YP_061437.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_338421.1| sensor histidine kinase [Mycobacterium tuberculosis CDC1551]). pfam00512, HisKA, His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal.; Specificity unclear; putative two-component system, sensor kinase complement(3094037..3095713) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173567 YP_001223511.1 CDS CMM_2766 NC_009480.1 3095710 3096483 R putative two-component system, response regulator (YP_061436.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225501.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Kineococcus radiotolerans SRS30216]). pfam00072,Response_reg, Response regulator receiver domain. pfam00486, Trans_reg_C, Transcriptional regulatory protein, C terminal.; Specificity unclear; putative two-component system, response regulator complement(3095710..3096483) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174787 YP_001223512.1 CDS CMM_2767 NC_009480.1 3096554 3097384 R Hypothetical protein; hypothetical protein complement(3096554..3097384) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173859 YP_001223513.1 CDS CMM_2768 NC_009480.1 3097455 3098483 R conserved membrane protein, putative exporter (YP_120073.1| putative transporter membrane protein [Nocardia farcinica IFM 10152]; NP_738469.1| putative integral membrane export protein [Corynebacterium efficiens YS-314]). pfam03741, TerC, Integral membrane protein TerC family.; Family membership; putative exporter complement(3097455..3098483) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173217 YP_001223514.1 CDS CMM_2769 NC_009480.1 3098668 3099606 R conserved hypothetical protein (ZP_00309143.1| COG0823: Periplasmic component of the Tol biopolymer transport system [Cytophaga hutchinsonii]; Q8UEU8|YG56_AGRT5 Hypothetical protein ATU1656/AGR_C_3050).; Family membership; hypothetical protein complement(3098668..3099606) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173837 YP_001223515.1 CDS CMM_2770 NC_009480.1 3099603 3100676 R conserved hypothetical protein (NP_630651.1| putative DNA-binding protein [Streptomyces coelicolor A3(2)]; ZP_00186827.1| COG1082: Sugar phosphate isomerases/epimerases [Rubrobacter xylanophilus DSM 9941]). pfam01261, AP_endonuc_2, AP endonuclease family 2.; hypothetical protein complement(3099603..3100676) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175588 YP_001223516.1 CDS CMM_2771 NC_009480.1 3100799 3101581 R putative multidrug ABC transporter, permease component (NP_981776.1| ABC transporter, permease protein,putative [Bacillus cereus ATCC 10987]; AAF12290.1| conserved hypothetical protein [Deinococcus radiodurans]). pfam03699, UPF0182, Uncharacterised protein family (UPF0182). This family contains uncharacterised integral membrane proteins.; Specificity unclear; putative multidrug ABC transporter permease complement(3100799..3101581) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174022 YP_001223517.1 CDS CMM_2772 NC_009480.1 3101578 3102534 R putative ABC transporter, ATP-binding protein (NP_629278.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]; NP_285331.1| ABC transporter, ATP-binding protein, putative [Deinococcus radiodurans R1]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative ABC transporter ATP-binding protein complement(3101578..3102534) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174434 YP_001223518.1 CDS CMM_2773 NC_009480.1 3102527 3103495 R conserved hypothetical protein, putative nitroreductase (NP_578479.1| putative NADH oxidase [Pyrococcus furiosus DSM 3638]; ZP_00294650.1| COG0778: Nitroreductase [Methanosarcina barkeri str. fusaro]).; Family membership; putative nitroreductase complement(3102527..3103495) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174062 YP_001223519.1 CDS CMM_2774 NC_009480.1 3103554 3104816 R conserved hypothetical protein (YP_055575.1| conserved protein DUF181 [Propionibacterium acnes KPA171202]; Q58494|YA94_METJA Hypothetical UPF0142 protein MJ1094). pfam02624, DUF181, Uncharacterized ACR,COG1944.; hypothetical protein complement(3103554..3104816) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172982 YP_001223520.1 CDS CMM_2775 NC_009480.1 3104813 3105724 R hypothetical protein complement(3104813..3105724) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174765 YP_001223521.1 CDS CMM_2776 NC_009480.1 3105735 3105947 R hypothetical protein complement(3105735..3105947) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173902 YP_001223522.1 CDS CMM_2777 NC_009480.1 3106119 3106781 D conserved hypothetical protein (YP_061428.1| hypothetical protein Lxx02960 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_950795.1| hypothetical protein [Onion yellows phytoplasma OY-M]; ZP_00040545.1| COG5377: Phage-related protein, predicted endonuclease [Xylella fastidiosa Ann-1]).; hypothetical protein 3106119..3106781 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175873 YP_001223523.1 CDS CMM_2778 NC_009480.1 3106979 3108031 D putative zinc-dependant oxidoreductase (YP_061427.1| zinc-binding oxidoreductase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629556.1| putative zinc-binding oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00297421.1| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases [Methanosarcina barkeri str. fusaro]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily.; Function unclear; putative zinc-dependent oxidoreductase 3106979..3108031 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175812 YP_001223524.1 CDS CMM_2779 NC_009480.1 3108196 3109407 R putative carboxylesterase, putative penicillin-binding protein (ZP_00126504.2| COG1680: Beta-lactamase class C and other penicillin binding proteins [Pseudomonas syringae pv. syringae B728a]; NP_824788.1| putative esterase [Streptomyces avermitilis MA-4680]). pfam00144,Beta-lactamase, Beta-lactamase.; Function unclear; putative carboxylesterase complement(3108196..3109407) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174226 YP_001223525.1 CDS CMM_2780 NC_009480.1 3109404 3110396 R putative sugar hydrolase (CAD47861.1| putative sucrose hydrolase [Arthrobacter nicotinovorans]).; Function unclear; hypothetical protein complement(3109404..3110396) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173775 YP_001223526.1 CDS CMM_2781 NC_009480.1 3110396 3111220 R putative sugar ABC transporter, permease component (ZP_00206541.1| COG0395: ABC-type sugar transport system,permease component [Bifidobacterium longum DJO10A]; NP_107402.1| ABC transporter, permease protein [Mesorhizobium loti MAFF303099]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative sugar ABC transporter permease complement(3110396..3111220) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174310 YP_001223527.1 CDS CMM_2782 NC_009480.1 3111217 3112212 R putative sugar ABC transporter, permease component (ZP_00206542.1| COG1175: ABC-type sugar transport systems,permease components [Bifidobacterium longum DJO10A]; ZP_00183308.1| COG1175: ABC-type sugar transport systems,permease components [Exiguobacterium sp. 255-15]).; Specificity unclear; putative sugar ABC transporter permease complement(3111217..3112212) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175853 YP_001223528.1 CDS CMM_2783 NC_009480.1 3112209 3113558 R putative sugar ABC transporter, substrate binding protein (ZP_00121121.2| COG1653: ABC-type sugar transport system, periplasmic component [Bifidobacterium longum DJO10A]; NP_107400.1| ABC transporter, periplasmic binding-protein [Mesorhizobium loti MAFF303099]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter substrate binding protein complement(3112209..3113558) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174527 YP_001223529.1 CDS CMM_2784 NC_009480.1 3113760 3114845 D putative transcriptional regulator, LacI-family (ZP_00033618.1| COG1609: Transcriptional regulators [Burkholderia fungorum]; NP_231357.1| transcriptional regulator, LacI family [Vibrio cholerae O1 biovar eltor str. N16961]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; LacI family transcriptional regulator 3113760..3114845 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174600 YP_001223530.1 CDS CMM_2785 NC_009480.1 3114871 3115467 R putative acetyltransferase (YP_119942.1| putative acetyltransferase [Nocardia farcinica IFM 10152]; NP_961723.1| hypothetical protein MAP2789 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase.; Function unclear; putative acetyltransferase complement(3114871..3115467) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175366 YP_001223531.1 CDS rplA NC_009480.1 3115572 3116258 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(3115572..3116258) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174123 YP_001223532.1 CDS rplK NC_009480.1 3116358 3116789 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(3116358..3116789) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175822 YP_001223533.1 CDS nusG NC_009480.1 3116843 3117865 R putative transcription antitermination protein (YP_061423.1| transcription antitermination factor [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787843.1| transcription antitermination protein [Tropheryma whipplei str. Twist]). pfam02357, NusG, Transcription termination factor nusG. pfam00467, KOW, KOW motif. The KOW (Kyprides,Ouzounis, Woese) motif is found in a variety of ribosomal proteins and NusG. InterPro: Bacterial transcription antitermination protein nusG.; High confidence in function and specificity; putative transcription antitermination protein complement(3116843..3117865) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173612 YP_001223534.1 CDS secE NC_009480.1 3118053 3118325 R forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(3118053..3118325) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175607 YP_001223535.1 CDS aspC NC_009480.1 3118661 3119890 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 3118661..3119890 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175466 YP_001223536.1 CDS murB NC_009480.1 3119924 3121078 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(3119924..3121078) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175126 YP_001223537.1 CDS CMM_2792 NC_009480.1 3121086 3121520 R conserved hypothetical protein, putative dehydratase (YP_061419.1| hypothetical protein Lxx02820 [Leifsonia xyli subsp. xyli str.CTCB07]; NP_826079.1| hypothetical protein SAV4902 [Streptomyces avermitilis MA-4680]). , pfam01575, MaoC_dehydratas, MaoC like domain. ,InterPro: MaoC-like dehydratase domain.; Family membership; putative dehydratase complement(3121086..3121520) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174355 YP_001223538.1 CDS CMM_2793 NC_009480.1 3121517 3121966 R conserved hypothetical protein, putative dehydratase (YP_061418.1| hypothetical protein Lxx02810 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00292077.1| COG2030: Acyl dehydratase [Thermobifida fusca]). pfam05921, DUF875, Actinomycete protein of unknown function (DUF875). arcC: carbamate kinase; Family membership; hypothetical protein complement(3121517..3121966) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173581 YP_001223540.1 CDS CMM_2795 NC_009480.1 3122592 3122789 R hypothetical protein complement(3122592..3122789) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172983 YP_001223541.1 CDS CMM_2796 NC_009480.1 3123286 3124224 R putative oxidoreductase (NP_733626.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00106480.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Nostoc punctiforme PCC 73102]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. InterPro: Aldo/keto reductase family.; Function unclear; putative oxidoreductase complement(3123286..3124224) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175187 YP_001223542.1 CDS aglC NC_009480.1 3124385 3126124 D putative alpha-glucosidase, glycosyl hydrolase family 13 (NP_626479.1| alpha-glucosidase [Streptomyces coelicolor A3(2)]; ZP_00089179.1| COG0366: Glycosidases [Azotobacter vinelandii]). pfam00128, Alpha-amylase, Alpha amylase, catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases. InterPro: Glycoside hydrolase family 13.; Specificity unclear; alpha-glucosidase 3124385..3126124 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173223 YP_001223543.1 CDS CMM_2798 NC_009480.1 3126205 3127389 R putative membrane bound metalloendopeptidase,family M23 (NP_354816.1| AGR_C_3364p [Agrobacterium tumefaciens]; ZP_00193020.1| COG0739: Membrane proteins related to metalloendopeptidases [Mesorhizobium sp. BNC1]). pfam01551, Peptidase_M37, Peptidase family M23/M37. Members of this family are zinc metallopeptidases with a range of specificities. InterPro: Peptidase family M23/M37.; Family membership; M23 family membrane bound metalloendopeptidase complement(3126205..3127389) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172967 YP_001223544.1 CDS suhB NC_009480.1 3127615 3128424 R putative inositol-1-monophosphatase (Q92M71|SUHB_RHIME Inositol-1-monophosphatase (IMPase) (Inositol-1-phosphatase); AAF63339.1| myo-inositol-1-monophosphotase [Streptomyces spectabilis]). pfam00459,Inositol_P, Inositol monophosphatase family.; Specificity unclear; putative inositol-1-monophosphatase complement(3127615..3128424) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174608 YP_001223545.1 CDS CMM_2800 NC_009480.1 3128470 3129210 R conserved membrane protein (NP_962548.1| hypothetical protein MAP3614 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_827020.1| hypothetical protein SAV5843 [Streptomyces avermitilis MA-4680]). pfam06912, DUF1275, Protein of unknown function (DUF1275).; Conserved hypothetical protein; hypothetical protein complement(3128470..3129210) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175738 YP_001223546.1 CDS CMM_2801 NC_009480.1 3129273 3130259 R putative oxidoreductase (NP_733626.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00106480.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Nostoc punctiforme PCC 73102]). pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative oxidoreductase complement(3129273..3130259) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173212 YP_001223547.1 CDS CMM_2802 NC_009480.1 3130585 3131073 D conserved hypothetical protein (NP_826073.1| hypothetical protein SAV4896 [Streptomyces avermitilis MA-4680]; YP_061355.1| hypothetical protein Lxx01880 [Leifsonia xyli subsp. xyli str. CTCB07]). pfam04461,DUF520, Protein of unknown function (DUF520). Family of uncharacterised proteins.; hypothetical protein 3130585..3131073 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174401 YP_001223548.1 CDS CMM_2803 NC_009480.1 3131155 3132624 D putative phospholipase, cardiolipin synthetase (YP_062936.1| cardiolipin synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787192.1| cardiolipin synthetase [Tropheryma whipplei str. Twist]). pfam00614, PLDc,Phospholipase D. Active site motif (twice). InterPro: Phospholipase D/Transphosphatidylase.; High confidence in function and specificity; putative phospholipase, cardiolipin synthetase 3131155..3132624 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174175 YP_001223549.1 CDS CMM_2804 NC_009480.1 3132652 3133146 R putative transcriptional regulator, MarR family (ZP_00058332.1| COG1846: Transcriptional regulators [Thermobifida fusca]; ZP_00227991.1| COG1846: Transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. InterPro: Bacterial regulatory protein MarR family.; Specificity unclear; MarR family transcriptional regulator complement(3132652..3133146) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175768 YP_001223550.1 CDS CMM_2805 NC_009480.1 3133271 3133954 R putative signalpeptidase (NP_628711.1| putative type IV peptidase [Streptomyces coelicolor A3(2)]; ZP_00171774.1| COG1989: Type II secretory pathway,prepilin signal peptidase PulO and related peptidases [Methylobacillus flagellatus KT]; AAG18589.1| pilin biogenesis protein PilD [Pseudomonas fluorescens]).; Conserved hypothetical protein; hypothetical protein complement(3133271..3133954) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174252 YP_001223551.1 CDS CMM_2806 NC_009480.1 3134092 3135462 R putative ferredoxin/ferredoxin-NADP reductase (YP_061354.1| ferredoxin/ferredoxin-NADP reductase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_121578.1| putative ferredoxin reductase [Nocardia farcinica IFM 10152]). possibly involved in menaquinone biosynthesis. pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase.; Specificity unclear; putative ferredoxin/ferredoxin-NADP reductase complement(3134092..3135462) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174969 YP_001223552.1 CDS menX NC_009480.1 3135553 3136626 R putative polyprenyl diphosphate synthase, involved in menaquinone biosynthesis (YP_061353.1| trans-hexaprenyltranstransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826041.1| putative polyprenyl diphosphate synthase [Streptomyces avermitilis MA-4680]). pfam00348, polyprenyl_synt, Polyprenyl synthetase. InterPro: Polyprenyl synthetase.; Specificity unclear; putative polyprenyl diphosphate synthase complement(3135553..3136626) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174791 YP_001223553.1 CDS menH NC_009480.1 3136662 3137396 R putative menaquinone biosynthesis methyltransferase (YP_061352.1| ubiquinone/menaquinone biosynthesis methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_121345.1| putative ubiquinone/ menaquinone methyltransferase [Nocardia farcinica IFM 10152]). pfam01209, Ubie_methyltran, ubiE/COQ5 methyltransferase family. InterPro: ubiE/COQ5 methyltransferase.; Specificity unclear; putative menaquinone biosynthesis methyltransferase complement(3136662..3137396) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174079 YP_001223554.1 CDS CMM_2809 NC_009480.1 3137404 3140142 R putative sugar MFS permease (NP_629540.1| probable integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00209176.1| COG0477: Permeases of the major facilitator superfamily [Magnetospirillum magnetotacticum MS-1]). pfam05977, DUF894, Bacterial protein of unknown function (DUF894).; Function unclear; putative sugar MFS permease complement(3137404..3140142) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174865 YP_001223555.1 CDS menF NC_009480.1 3137557 3138831 D putative isochorismate synthase (YP_061351.1| isochorismate mutase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00292873.1| COG1169: Isochorismate synthase [Thermobifida fusca]). pfam00425, Chorismate_bind,chorismate binding enzyme. InterPro: Isochorismate synthase.; High confidence in function and specificity; putative isochorismate synthase 3137557..3138831 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175068 YP_001223556.1 CDS CMM_2811 NC_009480.1 3140139 3140684 R putative transcriptional regulator, ArsR family (NP_826320.1| hypothetical protein SAV5143 [Streptomyces avermitilis MA-4680]; NP_579519.1| transcriptional regulatory protein arsR family [Pyrococcus furiosus DSM 3638])., , pfam01022, HTH_5, Bacterial regulatory protein,arsR family.; Function unclear; hypothetical protein complement(3140139..3140684) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175595 YP_001223557.1 CDS menD NC_009480.1 3140800 3142566 R menaquinone biosynthesis bifunctional protein menD contains two activities: 2-succinyl-6-hydroxy-24-cyclohexadiene- 1-carboxylate synthase (EC 4.1.3.-) and 2-oxoglutarate decarboxylase (EC 4.1.1.71) (Alpha-ketoglutarate decarboxylase)] (YP_061328.1| 2-oxoglutarate decarboxylase; 2-succinyl-6-hydroxy- 2,4-cyclohexadiene-1-carboxylate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789026.1| putative menaquinone biosynthesis protein MenD [Tropheryma whipplei TW08/27]. pfam02776,TPP_enzyme_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. InterPro: Menaquinone biosynthesis protein.; High confidence in function and specificity; menaquinone biosynthesis bifunctional protein menD complement(3140800..3142566) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173302 YP_001223558.1 CDS CMM_2813 NC_009480.1 3142573 3142995 R hypothetical membrane protein (YP_061327.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628654.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; Hypothetical protein; hypothetical protein complement(3142573..3142995) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173661 YP_001223559.1 CDS CMM_2814 NC_009480.1 3143135 3143515 D hypothetical membrane protein (ZP_00292109.1| hypothetical protein Tfus02002535 [Thermobifida fusca]).; hypothetical protein 3143135..3143515 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172933 YP_001223560.1 CDS CMM_2815 NC_009480.1 3143526 3143903 R hypothetical protein complement(3143526..3143903) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175181 YP_001223561.1 CDS menA NC_009480.1 3143909 3144793 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(3143909..3144793) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175393 YP_001223562.1 CDS CMM_2817 NC_009480.1 3144952 3145704 R putative mutase (NP_822948.1| putative mutase [Streptomyces avermitilis MA-4680]; NP_896839.1| putative phosphoglycerate mutase family protein [Synechococcus sp. WH 8102]; NP_962249.1| EntD [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00300, PGAM,Phosphoglycerate mutase family.; Family membership; putative mutase complement(3144952..3145704) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175350 YP_001223563.1 CDS CMM_2818 NC_009480.1 3145803 3146711 R conserved hypothetical protein (YP_061292.1| beta-lactamase related protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00106502.1| COG2367: Beta-lactamase class A [Nostoc punctiforme PCC 73102]).; hypothetical protein complement(3145803..3146711) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172936 YP_001223564.1 CDS CMM_2819 NC_009480.1 3146734 3148716 R putative metallopeptidase, family M13 (YP_061291.1| metallopeptidase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_121856.1| putative peptidase [Nocardia farcinica IFM 10152]). pfam05649, Peptidase_M13_N,Peptidase family M13. pfam01431, Peptidase_M13, Peptidase family M13.; Function unclear; metallopeptidase family M13 complement(3146734..3148716) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173281 YP_001223565.1 CDS CMM_2820 NC_009480.1 3148824 3149030 D putative transcriptional regulator, Cro/CI family (NP_639310.1| transcriptional regulator [Xanthomonas campestris pv. campestris str. ATCC 33913]; ZP_00225863.1| COG1476: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator 3148824..3149030 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174023 YP_001223566.1 CDS CMM_2821 NC_009480.1 3149014 3149415 D Hypothetical protein; hypothetical protein 3149014..3149415 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175573 YP_001223567.1 CDS CMM_2822 NC_009480.1 3149521 3150804 D putative xanthine/uracil family permease, NCS2 family (YP_104807.1| xanthine/uracil permease family protein [Burkholderia mallei ATCC 23344]; ZP_00275416.1| COG2233: Xanthine/uracil permeases [Ralstonia metallidurans CH34]). pfam00860, Xan_ur_permease, Permease family.; Specificity unclear; xanthine/uracil family permease 3149521..3150804 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174511 YP_001223568.1 CDS CMM_2823 NC_009480.1 3150990 3152369 D conserved membrane protein (YP_062737.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055965.1| hypothetical protein PPA1260 [Propionibacterium acnes KPA171202]).; Conserved hypothetical protein; hypothetical protein 3150990..3152369 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175161 YP_001223569.1 CDS CMM_2824 NC_009480.1 3152348 3154141 R catalyzes the hydrolysis of allophanate; allophanate hydrolase complement(3152348..3154141) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175502 YP_001223570.1 CDS CMM_2825 NC_009480.1 3154138 3154869 R conserved hypothetical protein, isochorismatase family (NP_772791.1| hypothetical isochorismatase family protein [Bradyrhizobium japonicum]; ZP_00125671.2| COG1335: Amidases related to nicotinamidase [Pseudomonas syringae pv. syringae B728a]). pfam00857, Isochorismatase,Isochorismatase family. This family are hydrolase enzymes.; hypothetical protein complement(3154138..3154869) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173116 YP_001223571.1 CDS CMM_2826 NC_009480.1 3154866 3156242 R putative cytosine permease, NCS1 family (NP_937310.1| purine-cytosine permease [Vibrio vulnificus YJ016]; NP_462243.1| putative purine-cytosine permease [Salmonella typhimurium LT2]). pfam02133, Transp_cyt_pur,Permease for cytosine/purines, uracil, thiamine,allantoin. InterPro: Permeases for cytosine/purines uracil thiamine allantoin; Specificity unclear; cytosine permease complement(3154866..3156242) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175574 YP_001223572.1 CDS CMM_2827 NC_009480.1 3156391 3157080 D putative transcriptional regulator, GntR-family (NP_715986.1| transcriptional regulator. GntR family [Shewanella oneidensis MR-1]; NP_823595.1| putative GntR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00392, GntR, Bacterial regulatory proteins,gntR family.; Specificity unclear; GntR family transcriptional regulator 3156391..3157080 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175312 YP_001223573.1 CDS CMM_2828 NC_009480.1 3157101 3157799 R putative phosphatase (NP_662590.1| hydrolase,haloacid dehalogenase- like family [Chlorobium tepidum TLS]; ZP_00306861.1| COG0546: Predicted phosphatases [Ferroplasma acidarmanus]; ZP_00057308.1| COG0546: Predicted phosphatases [Thermobifida fusca]). pfam00702,Hydrolase, haloacid dehalogenase-like hydrolase. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.; Function unclear; putative phosphatase complement(3157101..3157799) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173756 YP_001223574.1 CDS CMM_2829 NC_009480.1 3157838 3158350 R putative transcriptional regulator, MarR family (YP_062606.1| transcriptional regulator, MarR family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824748.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; hypothetical protein complement(3157838..3158350) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175928 YP_001223575.1 CDS mmuM NC_009480.1 3158485 3159390 D converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 3158485..3159390 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174965 YP_001223576.1 CDS CMM_2831 NC_009480.1 3159476 3160339 R putative nucleoside-diphosphate-sugar epimerase (YP_062550.1| hypothetical protein Lxx16700 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_600590.1| predicted nucleoside-diphosphate-sugar epimerase [Corynebacterium glutamicum ATCC 13032]). only weak similarity to: pfam02716, Isoflavone_redu, Isoflavone reductase.; Function unclear; putative nucleoside-diphosphate-sugar epimerase complement(3159476..3160339) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175712 YP_001223577.1 CDS CMM_2832 NC_009480.1 3160454 3160834 D putative transcriptional regulator (NP_629709.1| conserved hypothetical protein SC7A1.18c [Streptomyces coelicolor A3(2)]; NP_695657.1| narrowly conserved hypothetical protein with duf24 [Bifidobacterium longum NCC2705]). pfam01638, DUF24, Transcriptional regulator.; Function unclear; putative transcriptional regulator 3160454..3160834 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175864 YP_001223578.1 CDS CMM_2833 NC_009480.1 3160911 3162206 D putative MFS permease (NP_631565.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00294170.1| COG0477: Permeases of the major facilitator superfamily [Thermobifida fusca]). pfam00083,Sugar_tr, Sugar (and other) transporter.; Function unclear; putative MFS permease 3160911..3162206 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174672 YP_001223579.1 CDS CMM_2834 NC_009480.1 3162309 3163175 D putative aldo/keto reductase (YP_119166.1| putative oxidoreductase [Nocardia farcinica IFM 10152]; NP_624627.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. InterPro: Aldo/keto reductase family.; Function unclear; putative oxidoreductase 3162309..3163175 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175870 YP_001223580.1 CDS CMM_2835 NC_009480.1 3163203 3164138 R putative transcriptional regulator, LysR-family (ZP_00226031.1| COG0583: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; ZP_00057998.1| COG0583: Transcriptional regulator [Thermobifida fusca]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate, LysR substrate binding domain.; Specificity unclear; LysR family transcriptional regulator complement(3163203..3164138) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175734 YP_001223581.1 CDS CMM_2836 NC_009480.1 3164228 3165205 D putative permease, DMT family (NP_823168.1| hypothetical protein SAV1992 [Streptomyces avermitilis MA-4680]; ZP_00279369.1| COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily [Burkholderia fungorum LB400]). pfam00892, DUF6, Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function (twice).; Specificity unclear; permease DMT family 3164228..3165205 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173087 YP_001223582.1 CDS CMM_2837 NC_009480.1 3165202 3165591 D putative membrane protein (ZP_00199035.1| hypothetical protein Krad07002569 [Kineococcus radiotolerans SRS30216]; NP_599355.1| predicted membrane protein [Corynebacterium glutamicum ATCC 13032]). pfam02656, DUF202, Domain of unknown function DUF. InterPro: DUF202.; hypothetical protein 3165202..3165591 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173763 YP_001223583.1 CDS CMM_2838 NC_009480.1 3165588 3165944 D putative membrane protein (ZP_00292261.1| hypothetical protein Tfus02002381 [Thermobifida fusca]; NP_418131.1| hypothetical protein b3675 [Escherichia coli K12]).; hypothetical protein 3165588..3165944 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173182 YP_001223584.1 CDS CMM_2839 NC_009480.1 3165974 3166843 R conserved hypothetical protein, putative nucleoside-diphosphate-sugar epimerase (NP_792815.1| conserved hypothetical protein [Pseudomonas syringae pv. tomato str. DC3000]; NP_969467.1| conserved hypothetical protein [Bdellovibrio bacteriovorus HD100]).; Family membership; putative nucleoside-diphosphate-sugar epimerase complement(3165974..3166843) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175832 YP_001223585.1 CDS CMM_2840 NC_009480.1 3167078 3167968 R putative sugar kinase (ZP_00293678.1| COG0524: Sugar kinases, ribokinase family [Thermobifida fusca]; ZP_00337675.1| COG0524: Sugar kinases, ribokinase family [Silicibacter sp. TM1040]). pfam00294, PfkB, pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases.; Specificity unclear; putative sugar kinase complement(3167078..3167968) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175381 YP_001223586.1 CDS CMM_2841 NC_009480.1 3167961 3169025 R putative ranscriptional regulator, LacI-family (NP_625372.1| putative lacI-family transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00186316.1| COG1609: Transcriptional regulators [Rubrobacter xylanophilus DSM 9941]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. InterPro: Periplasmic binding proteins and sugar binding domain LacI family.; Specificity unclear; LacI family transcriptional regulator complement(3167961..3169025) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174027 YP_001223587.1 CDS CMM_2842 NC_009480.1 3169139 3170239 D putative sugar ABC transporter, substrate binding protein (NP_530772.1| ABC transporter, substrate binding protein [sugar] [Agrobacterium tumefaciens str. C58]; NP_107869.1| sugar ABC transporter, periplasmic sugar-binding protein [Mesorhizobium loti MAFF303099]). pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; putative sugar ABC transporter substrate binding protein 3169139..3170239 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175700 YP_001223588.1 CDS CMM_2843 NC_009480.1 3170242 3171288 D putative sugar ABC transporter, permease component (ZP_00338367.1| COG1172: Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Silicibacter sp. TM1040]; AAC16210.1| ribose transport system permease protein RbsC [Rhodobacter capsulatus]). pfam02653, BPD_transp_2,Branched-chain amino acid transport system / permease component.; Specificity unclear; putative sugar ABC transporter permease 3170242..3171288 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174887 YP_001223589.1 CDS CMM_2844 NC_009480.1 3171285 3172082 D putative sugar ABC transporter, ATP-binding protein (NP_530774.1| ABC transporter, nucleotide binding/ATPase protein [sugar] [Agrobacterium tumefaciens str. C58]; NP_107871.1| sugar ABC transporter, ATP binding protein [Mesorhizobium loti MAFF303099]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative sugar ABC transporter ATP-binding protein 3171285..3172082 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175353 YP_001223590.1 CDS CMM_2845 NC_009480.1 3172079 3172372 D conserved hypothetical protein (NP_826883.1| hypothetical protein SAV5706 [Streptomyces avermitilis MA-4680]; ZP_00274581.1| COG1359: Uncharacterized conserved protein [Ralstonia metallidurans CH34]). pfam03992, ABM,Antibiotic biosynthesis monooxygenase. This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. InterPro: DUF176.; Function unclear; hypothetical protein 3172079..3172372 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174968 YP_001223591.1 CDS CMM_2846 NC_009480.1 3172596 3173699 R putative plasmid maintenance system, antidote protein (ZP_00271057.1| COG3093: Plasmid maintenance system antidote protein [Rhodospirillum rubrum]; YP_112809.1| DNA-binding protein [Methylococcus capsulatus str. Bath]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. pfam06114, DUF955, Domain of unknown function (DUF955). Family of bacterial and viral proteins with undetermined function.; Conserved hypothetical protein; putative plasmid maintenance system, antidote protein complement(3172596..3173699) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175721 YP_001223592.1 CDS CMM_2847 NC_009480.1 3173728 3174063 R putative plasmid maintemance system, killer protein complement(3173728..3174063) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173615 YP_001223593.1 CDS CMM_2848 NC_009480.1 3174495 3175247 R putative short chain dehydrogenase/oxidoreductase (ZP_00194667.1| COG1028: Dehydrogenases with different specificities (related to short- chain alcohol dehydrogenases) [Mesorhizobium sp. BNC1]; NP_631416.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase complement(3174495..3175247) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173692 YP_001223594.1 CDS CMM_2849 NC_009480.1 3175441 3177510 D conserved hypothetical protein, putative phosphatase (NP_825582.1| hypothetical protein SAV4405 [Streptomyces avermitilis MA-4680]; ZP_00188457.2| COG3211: Predicted phosphatase [Rubrobacter xylanophilus DSM 9941]). pfam05787, DUF839, Bacterial protein of unknown function (DUF839). This family consists of several bacterial proteins of unknown function.; Family membership; putative phosphatase 3175441..3177510 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175707 YP_001223595.1 CDS CMM_2850 NC_009480.1 3177707 3178060 D hypothetical protein (NP_870934.1| hypothetical protein RB13228 [Rhodopirellula baltica SH 1]; AAO55387.1| conserved hypothetical protein [Pseudomonas syringae pv. tomato str. DC3000]).; hypothetical protein 3177707..3178060 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175044 YP_001223596.1 CDS CMM_2851 NC_009480.1 3178108 3178713 D putative membrane protein (NP_959547.1| hypothetical protein MAP0613c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00293703.1| hypothetical protein Tfus02001064 [Thermobifida fusca]).; hypothetical protein 3178108..3178713 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174145 YP_001223597.1 CDS CMM_2852 NC_009480.1 3178770 3179507 D putative zinc transporter, ZIP family (ZP_00110916.1| COG0428: Predicted divalent heavy-metal cations transporter [Nostoc punctiforme PCC 73102]; ZP_00293877.1| COG0428: Predicted divalent heavy-metal cations transporter [Thermobifida fusca]). pfam02535, Zip,ZIP Zinc transporter. The ZIP family consists of zinc transport proteins and many putative metal transporters.; Specificity unclear; ZIP family zinc transporter 3178770..3179507 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175115 YP_001223598.1 CDS CMM_2853 NC_009480.1 3179562 3180116 R putative transcriptional regulator, MarR family (NP_824140.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_629113.1| putative marR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam01047,MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator complement(3179562..3180116) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174307 YP_001223599.1 CDS CMM_2854 NC_009480.1 3180258 3182069 D putative ATPase involved in chromosome partitioning (NP_301161.1| conserved hypothetical protein [Mycobacterium leprae TN]; ZP_00056814.1| COG0455: ATPases involved in chromosome partitioning [Thermobifida fusca]; AAP73957.1| putative septum site-determining protein (MinD) [Rhodococcus erythropolis]).; Family membership; hypothetical protein 3180258..3182069 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174197 YP_001223600.1 CDS CMM_2855 NC_009480.1 3182066 3183478 D conserved membrane protein, putative multidrug exporter MOP(MATE) family (NP_628096.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00291615.1| COG0534: Na+-driven multidrug efflux pump [Thermobifida fusca])., , pfam01554, MatE, MatE. The MatE domain (twice).; Specificity unclear; multidrug exporter MOPMATE family membrane protein 3182066..3183478 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174976 YP_001223601.1 CDS CMM_2856 NC_009480.1 3183494 3184354 R putative aldo/keto reductase (YP_074487.1| oxidoreductase [Symbiobacterium thermophilum IAM 14863]; ZP_00281237.1| COG0656: Aldo/keto reductases, related to diketogulonate reductase [Burkholderia fungorum LB400]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. InterPro: Aldo/keto reductase family. holB: DNA polymerase III delta prime s; Function unclear; putative aldo/keto reductase complement(3183494..3184354) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174073 YP_001223602.1 CDS CMM_2857 NC_009480.1 3184406 3184846 R hypothetical protein complement(3184406..3184846) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173811 YP_001223603.1 CDS CMM_2858 NC_009480.1 3184856 3185875 R conserved hypothetical protein, putative protein-S-isoprenylcysteine methyltransferase (Isoprenylcysteine carboxylmethyltransferase) (NP_869869.1| ; ZP_00191379.2| COG2020: Putative protein-S-isoprenylcysteine methyltransferase [Kineococcus radiotolerans SRS30216]).; Function unclear; S-isoprenylcysteine methyltransferase-like protein complement(3184856..3185875) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175868 YP_001223604.1 CDS CMM_2859 NC_009480.1 3185872 3186387 R conserved hypothetical protein (EAL05363.1| conserved hypothetical protein [Listeria monocytogenes str. 1/2a F6854]; NP_347636.1| Uncharacterized protein,homolog of yhfF B.subtilis [Clostridium acetobutylicum ATCC 824]). pfam06171, DUF984, Protein of unknown function (DUF984).; hypothetical protein complement(3185872..3186387) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175134 YP_001223605.1 CDS CMM_2860 NC_009480.1 3186445 3186981 D Hypothetical protein; hypothetical protein 3186445..3186981 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175311 YP_001223606.1 CDS CMM_2861 NC_009480.1 3187048 3187608 D putative acetyltransferase (NP_644579.1| acetyltransferase [Xanthomonas axonopodis pv. citri str. 306]; NP_925980.1| probable acetyltransferase [Gloeobacter violaceus PCC 7421]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase.; Function unclear; putative acetyltransferase 3187048..3187608 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175356 YP_001223607.1 CDS CMM_2862 NC_009480.1 3187605 3188123 R putative acetyltransferase (NP_626478.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]; NP_925980.1| probable acetyltransferase [Gloeobacter violaceus PCC 7421]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase.; Family membership; putative acetyltransferase complement(3187605..3188123) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174802 YP_001223608.1 CDS CMM_2863 NC_009480.1 3188177 3188785 D conserved membrane protein (NP_294914.1| hypothetical protein [Deinococcus radiodurans R1]; ZP_00185697.1| COG3548: Predicted integral membrane protein [Rubrobacter xylanophilus DSM 9941]). pfam06736,DUF1211, Protein of unknown function (DUF1211).; Conserved hypothetical protein; hypothetical protein 3188177..3188785 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173520 YP_001223609.1 CDS CMM_2864 NC_009480.1 3188818 3189879 D conserved membrane protein, putative DMT transporter (YP_063076.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_733531.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam00892, DUF6, Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function (twice). InterPro: Integral membrane protein DUF6.; Family membership; putative DMT transporter 3188818..3189879 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175398 YP_001223610.1 CDS CMM_2865 NC_009480.1 3189889 3190584 D conserved hypothetical protein (YP_061283.1| hypothetical protein Lxx00930 [Leifsonia xyli subsp. xyli str. CTCB07]; YP_117280.1| hypothetical protein nfa10710 [Nocardia farcinica IFM 10152]). pfam01939, DUF91, Protein of unknown function DUF91.; hypothetical protein 3189889..3190584 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173668 YP_001223611.1 CDS CMM_2866 NC_009480.1 3190640 3191359 D conserved hypothetical protein, putative hydrolase (YP_061281.1| hydrolase, haloacid dehalogenase-like family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_816534.1| hydrolase, haloacid dehalogenase-like family [Enterococcus faecalis V583]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. InterPro: Haloacid dehalogenase/epoxide hydrolase family. hstdl_phs_rel: histidinol phosphatase-r; putative hydrolase 3190640..3191359 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173170 YP_001223612.1 CDS CMM_2867 NC_009480.1 3191473 3191934 D putative transcriptional regulator, MarR family (ZP_00227991.1| COG1846: Transcriptional regulators [Kineococcus radiotolerans SRS30216]; ZP_00058332.1| COG1846: Transcriptional regulators [Thermobifida fusca]). pfam01047, MarR, MarR family. InterPro: Bacterial regulatory protein MarR family.; Specificity unclear; MarR family transcriptional regulator 3191473..3191934 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172998 YP_001223613.1 CDS CMM_2868 NC_009480.1 3191994 3192863 D putative membrane-bound Zn-dependent protease (YP_118728.1| hypothetical protein nfa25170 [Nocardia farcinica IFM 10152]; NP_736926.1| hypothetical protein CE0316 [Corynebacterium efficiens YS-314]).; Function unclear; putative membrane-bound Zn-dependent protease 3191994..3192863 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173652 YP_001223614.1 CDS CMM_2869 NC_009480.1 3193115 3194224 D conserved membrane protein (YP_061832.1| hypothetical protein Lxx08200 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_738791.1| hypothetical protein CE2181 [Corynebacterium efficiens YS-314]). contains two domains: N-terminal: COG1633, Uncharacterized conserved protein [Function unknown]; cd01044, Ferritin_like_CCC1, Ferritin-like domain present at the N-terminus of the iron transport protein CCC1 of some eubacteria and archaebacteria, and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. This uncharacterized domain has the conserved residues of a diiron center. C-terminal: pfam01988, DUF125, Integral membrane protein DUF125. This family of predicted integral membrane proteins has no known function.; hypothetical protein 3193115..3194224 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175690 YP_001223615.1 CDS CMM_2870 NC_009480.1 3194287 3194934 D hypothetical protein 3194287..3194934 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173637 YP_001223616.1 CDS pgaA NC_009480.1 3194955 3196445 R putative polygalacturonase (Pectinase) (YP_061794.1| endopolygalacturonase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_638805.1| endopolygalacturonase [Xanthomonas campestris pv. campestris str. ATCC 33913]). , pfam00295, Glyco_hydro_28, Glycosyl hydrolases family 28. , InterPro: Glycoside hydrolase family 28.; High confidence in function and specificity; hypothetical protein complement(3194955..3196445) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175468 YP_001223617.1 CDS CMM_2872 NC_009480.1 3196563 3197429 R putative hydrolase/acyltransferase (NP_421198.1| acetoin dehydrogenase E2 component, putative [Caulobacter crescentus CB15]; BAC75995.1| meta cleavage compound hydrolase [Terrabacter sp. DBF63]). pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Family membership; putative hydrolase/acyltransferase complement(3196563..3197429) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174871 YP_001223618.1 CDS CMM_2873 NC_009480.1 3197579 3198913 D catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 3197579..3198913 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175753 YP_001223619.1 CDS CMM_2874 NC_009480.1 3198968 3199315 R conserved hypothetical protein (NP_142428.2| hypothetical protein PH0448 [Pyrococcus horikoshii OT3]; NP_614860.1| hypothetical protein MK1577 [Methanopyrus kandleri AV19]). pfam04266, DUF437, Protein of unknown function (DUF437).; hypothetical protein complement(3198968..3199315) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175463 YP_001223620.1 CDS CMM_2875 NC_009480.1 3199354 3199821 R conserved hypothetical protein (YP_061264.1| hypothetical protein Lxx00670 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824697.1| hypothetical protein SAV3520 [Streptomyces avermitilis MA-4680]). weak similarity to: COG4319, Ketosteroid isomerase homolog [Function unknown].; hypothetical protein complement(3199354..3199821) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175383 YP_001223621.1 CDS CMM_2876 NC_009480.1 3199850 3200512 R putative two-component system, response regulator (NP_599321.1| two-component system response regulator [Corynebacterium glutamicum ATCC 13032]; YP_062659.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_823607.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]). pfam00072, Response_reg, Response regulator receiver domain. InterPro: Response regulator receiver domain.; Specificity unclear; putative two-component system, response regulator complement(3199850..3200512) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175109 YP_001223622.1 CDS CMM_2877 NC_009480.1 3200509 3202332 R putative two-component system, sensor kinase (YP_062660.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_599320.1| two-component system sensory transduction histidine kinase [Corynebacterium glutamicum ATCC 13032]; NP_629952.1| putative two-component sensor [Streptomyces coelicolor A3(2)]). pfam00989, PAS, PAS domain. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal.; Specificity unclear; putative two-component system, sensor kinase complement(3200509..3202332) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174457 YP_001223623.1 CDS CMM_2878 NC_009480.1 3202468 3203919 D putative citrate transporter, CitMHS family (YP_062661.1| Mg++/citrate complex transporter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_599319.2| H+/citrate symporter [Corynebacterium glutamicum ATCC 13032]). pfam03600, CitMHS, Citrate transporter. InterPro: Citrate transporter.; High confidence in function and specificity; citrate transporter 3202468..3203919 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174799 YP_001223624.1 CDS CMM_2879 NC_009480.1 3204043 3205512 R conserved membrane protein (NP_821248.1| hypothetical protein SAV74 [Streptomyces avermitilis MA-4680]; ZP_00175585.2| COG3463: Predicted membrane protein [Crocosphaera watsonii WH 8501]).; Conserved hypothetical protein; hypothetical protein complement(3204043..3205512) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173877 YP_001223625.1 CDS CMM_2880 NC_009480.1 3205613 3206044 R conserved hypothetical protein (YP_061782.1| hypothetical protein Lxx07570 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_822361.1| hypothetical protein SAV1186 [Streptomyces avermitilis MA-4680]).; hypothetical protein complement(3205613..3206044) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174428 YP_001223626.1 CDS CMM_2881 NC_009480.1 3206148 3207173 D putative transcriptional regulator, LysR family (YP_120335.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]; NP_625268.1| putative lysR-family trancsriptional regulator [Streptomyces coelicolor A3(2)]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate,LysR substrate binding domain. InterPro: Bacterial regulatory protein LysR family.; Specificity unclear; LysR family transcriptional regulator 3206148..3207173 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174316 YP_001223627.1 CDS CMM_2882 NC_009480.1 3207204 3207935 R hypothetical protein (NP_104793.1| hypothetical protein mlr3756 [Mesorhizobium loti MAFF303099]; YP_133572.1| hypothetical protein PBPRB1925 [Photobacterium profundum SS9]).; hypothetical protein complement(3207204..3207935) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174694 YP_001223628.1 CDS CMM_2883 NC_009480.1 3208085 3208432 D hypothetical protein 3208085..3208432 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175951 YP_001223629.1 CDS ubiA NC_009480.1 3208462 3209358 R crtEb; UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase complement(3208462..3209358) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174335 YP_001223630.1 CDS crtY2 NC_009480.1 3209351 3209719 R putative C50 carotenoid epsilon cyclase/lycopene e-cyclase isoprenoid transferase B (NP_737248.1| C50 carotenoid epsilon cyclase [Corynebacterium efficiens YS-314]; lycopene e-cyclase isoprenoid transferase B [Agromyces mediolanus]).; High confidence in function and specificity; putative C50 carotenoid epsilon cyclase complement(3209351..3209719) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175127 YP_001223631.1 CDS crtY1 NC_009480.1 3209716 3210060 R putative C50 carotenoid epsilon cyclase (NP_599857.1| C50 carotenoid epsilon cyclase [Corynebacterium glutamicum ATCC 13032]; AAM94365.1| lycopene e-cyclase isoprenoid transferase A [Agromyces mediolanus]).; High confidence in function and specificity; putative C50 carotenoid epsilon cyclase complement(3209716..3210060) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174222 YP_001223632.1 CDS crtBI NC_009480.1 3210060 3212705 R putative bifunctional phytoene synthase/phytoene dehydrogenase ( N-terminal, COG1562, ERG9,Phytoene/squalene synthetase; pfam00494, SQS_PSY,Squalene/phytoene synthase. (AAM94363.1| phytoene synthase [Agromyces mediolanus]; AAK64298.1| phytoene synthase [Corynebacterium glutamicum]). C-terminal, COG1233,COG1233, Phytoene dehydrogenase and related proteins (Phytoene dehydrogenase (Phytoene desaturase). (AAM94364.1| phytoene desaturase [Agromyces mediolanus]; AAK64299.1| phytoene desaturase [Corynebacterium glutamicum]). CAROTENOID BIOSYNTHESIS; High confidence in function and specificity; putative bifunctional phytoene synthase/phytoene dehydrogenase complement(3210060..3212705) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173765 YP_001223633.1 CDS crtE NC_009480.1 3212702 3213724 R putative geranylgeranyl pyrophosphate synthase [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)] (AAF65590.1| GGPP synthase [Brevibacterium linens]; YP_062473.1| geranylgeranyl pyrophosphate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; AAM94362.1| geranylgeranyl pyrophosphate synthase [Agromyces mediolanus]). pfam00348,polyprenyl_synt, Polyprenyl synthetase. InterPro: Polyprenyl synthetase.; High confidence in function and specificity; putative geranylgeranyl pyrophosphate synthase complement(3212702..3213724) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173032 YP_001223634.1 CDS idiA NC_009480.1 3213817 3214401 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3213817..3214401 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173455 YP_001223635.1 CDS CMM_2890 NC_009480.1 3214474 3215352 R conserved hypothetical protein, putative phospholipase (NP_629464.1| hypothetical protein SCO5322 [Streptomyces coelicolor A3(2)]; NP_335532.1| hypothetical protein MT1092 [Mycobacterium tuberculosis CDC1551]). pfam01734, Patatin, Patatin-like phospholipase. This family consists of various patatin glycoproteins from plants. hydrog_prot: hydrogenase maturation prot; Function unclear; putative phospholipase complement(3214474..3215352) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174394 YP_001223636.1 CDS CMM_2891 NC_009480.1 3215480 3216064 R putative transcription regulator, MarR family (YP_062474.1| transcriptional regulator, MarR family [Leifsonia xyli subsp. xyli str. CTCB07]; CAF19334.1| transcriptional regulator, MarR family [Corynebacterium glutamicum ATCC 13032]; NP_625140.1| putative marR-family transcriptional regulator [Streptomyces coelicolor A3(2)). pfam01047, MarR, MarR family.; Specificity unclear; MarR family transcriptional regulator complement(3215480..3216064) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174781 YP_001223637.1 CDS CMM_2892 NC_009480.1 3216142 3218220 D putative RND family transporter (Q53902|MMLA_STRCO Putative membrane protein actII-3; YP_118784.1| putative membrane protein [Nocardia farcinica IFM 10152]). pfam03176, MMPL, MMPL family. Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport. InterPro: HMGCR/Patched 5TM box.; Conserved hypothetical protein; RND family transporter 3216142..3218220 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174284 YP_001223638.1 CDS CMM_2893 NC_009480.1 3218297 3219049 D putative short chain dehydrogenase/oxidoreductase (NP_465699.1| ; ZP_00103824.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Desulfitobacterium hafniense]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short chain dehydrogenase/oxidoreductase 3218297..3219049 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174896 YP_001223639.1 CDS CMM_2894 NC_009480.1 3219046 3219654 R putative transcriptional regulator, TetR family (ZP_00189647.3| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_963085.1| hypothetical protein MAP4151c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family.; Specificity unclear; TetR family transcriptional regulator complement(3219046..3219654) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175017 YP_001223640.1 CDS CMM_2895 NC_009480.1 3219715 3220203 D conserved hypothetical protein (NP_245758.1| unknown [Pasteurella multocida]; NP_758064.1| conserved hypothetical protein [Mycoplasma penetrans HF-2]).; hypothetical protein 3219715..3220203 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173540 YP_001223641.1 CDS CMM_2896 NC_009480.1 3220506 3221165 R hypothetical membrane protein (NP_821188.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00120603.2| hypothetical protein Blon03000461 [Bifidobacterium longum DJO10A]).; hypothetical protein complement(3220506..3221165) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173757 YP_001223642.1 CDS CMM_2897 NC_009480.1 3221309 3222004 R hypothetical membrane protein (NP_821188.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00120603.2| hypothetical protein Blon03000461 [Bifidobacterium longum DJO10A]).; hypothetical protein complement(3221309..3222004) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175375 YP_001223643.1 CDS aldA NC_009480.1 3222082 3223197 R putative L-alanine dehydrogenase (NP_827683.1| putative L-alanine dehydrogenase [Streptomyces avermitilis MA-4680]; AAM44187.1| L-alanine dehydrogenase [Mycobacterium smegmatis]). pfam05222, AlaDh_PNT_N,Alanine dehydrogenase/PNT, N-terminal domain. pfam01262,AlaDh_PNT_C, Alanine dehydrogenase/PNT, C-terminal domain. InterPro: Alanine dehydrogenase and pyridine nucleotide transhydrogenase.; High confidence in function and specificity; putative L-alanine dehydrogenase complement(3222082..3223197) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173813 YP_001223644.1 CDS CMM_2899 NC_009480.1 3223363 3223857 D putative leucine-responsive regulatory protein,AsnC family (NP_337354.1| transcriptional regulator, AsnC family [Mycobacterium tuberculosis CDC1551]; ZP_00226252.1| COG1522: Transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam01037,AsnC_trans_reg, AsnC family. The AsnC family is a family of similar bacterial transcription regulatory proteins. InterPro: Bacterial regulatory proteins AsnC family.; Specificity unclear; leucine-responsive regulatory protein 3223363..3223857 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173588 YP_001223645.1 CDS dcd NC_009480.1 3223871 3224476 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(3223871..3224476) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174678 YP_001223646.1 CDS CMM_2901 NC_009480.1 3224825 3227245 D hypothetical protein 3224825..3227245 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175367 YP_001223647.1 CDS CMM_2902 NC_009480.1 3228028 3228462 R hypothetical protein complement(3228028..3228462) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174386 YP_001223648.1 CDS CMM_2903 NC_009480.1 3228643 3229398 D putative ABC transporter, ATP-binding protein (NP_821704.1| putative ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]; NP_763672.1| ABC transporter (ATP-binding protein) [Staphylococcus epidermidis ATCC 12228]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative ABC transporter ATP-binding protein 3228643..3229398 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174109 YP_001223649.1 CDS CMM_2904 NC_009480.1 3229398 3230696 D hypothetical membrane protein (NP_939325.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]; YP_054886.1| hypothetical protein PPA0171 [Propionibacterium acnes KPA171202]).; hypothetical protein 3229398..3230696 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174835 YP_001223650.1 CDS CMM_2905 NC_009480.1 3230693 3231316 D Hypothetical protein; hypothetical protein 3230693..3231316 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173993 YP_001223651.1 CDS CMM_2906 NC_009480.1 3231313 3232077 R putative transcriptional regulator, GntR family (ZP_00051637.1| COG2186: Transcriptional regulators [Magnetospirillum magnetotacticum]; NP_739032.1| putative transcription factor [Corynebacterium efficiens YS-314]). pfam00392, GntR, Bacterial regulatory proteins, gntR family. InterPro: Bacterial regulatory proteins GntR family.; Specificity unclear; GntR family transcriptional regulator complement(3231313..3232077) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172951 YP_001223652.1 CDS gntK NC_009480.1 3232226 3232744 D putative gluconokinase (Gluconate kinase 2)(NP_625954.1| putative gluconokinase [Streptomyces coelicolor A3(2)]; ZP_00291960.1| COG3265: Gluconate kinase [Thermobifida fusca]).; Specificity unclear; putative gluconokinase 3232226..3232744 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173639 YP_001223653.1 CDS gntP NC_009480.1 3232827 3234227 D putative gluconate permease, GntP family (NP_602098.1| putative gluconate permease [Corynebacterium glutamicum ATCC 13032]; NP_283240.1| putative gluconate permease [Neisseria meningitidis Z2491]). , pfam02447,GntP_permease, GntP family permease. This is a family of integral membrane permeases that are involved in gluconate uptake.; High confidence in function and specificity; gluconate permease 3232827..3234227 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172955 YP_001223654.1 CDS CMM_2909 NC_009480.1 3234224 3234799 R putative pyridoxamine 5-phosphate oxidase (NP_681121.1| pyridoxamine 5'-phosphate oxidase [Thermosynechococcus elongatus BP-1]; NP_825001.1| putative oxidase [Streptomyces avermitilis MA-4680]). pfam01243, Pyridox_oxidase, Pyridoxamine 5'-phosphate oxidase. InterPro: Pyridoxamine 5-phosphate oxidase.; Specificity unclear; putative pyridoxamine 5-phosphate oxidase complement(3234224..3234799) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174951 YP_001223655.1 CDS CMM_2910 NC_009480.1 3234844 3235653 R putative DNA glycosylase/endonuclease VIII (NP_939193.1| Putative endonuclease [Corynebacterium diphtheriae NCTC 13129]; YP_062887.1| DNA glycosylase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam01149,Fapy_DNA_glyco, Formamidopyrimidine-DNA glycosylase N-terminal domain. Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidised purines from damaged DNA. pfam06831, H2TH, Formamidopyrimidine-DNA glycosylase H2TH domain.; Specificity unclear; putative DNA glycosylase/endonuclease VIII complement(3234844..3235653) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173038 YP_001223656.1 CDS CMM_2911 NC_009480.1 3235699 3236730 R Hypothetical protein; hypothetical protein complement(3235699..3236730) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174544 YP_001223657.1 CDS CMM_2912 NC_009480.1 3237001 3237747 D putative short-chain dehydrogenase (NP_793827.1| oxidoreductase, short-chain dehydrogenase/reductase family [Pseudomonas syringae pv. tomato str. DC3000]; NP_631846.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Function unclear; putative short-chain dehydrogenase/oxidoreductase 3237001..3237747 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173019 YP_001223658.1 CDS CMM_2913 NC_009480.1 3237806 3238822 D putative oxidoreductase (NP_626533.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00294380.1| COG0673: Predicted dehydrogenases and related proteins [Thermobifida fusca]). pfam01408,GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. pfam02894, GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain.; Function unclear; putative oxidoreductase 3237806..3238822 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175674 YP_001223659.1 CDS CMM_2914 NC_009480.1 3238887 3239504 D conserved hypothetical protein, putative reductase (NP_625187.1| putative secreted protein [Streptomyces coelicolor A3(2)]; NP_217570.1| hypothetical protein Rv3054c [Mycobacterium tuberculosis H37Rv]). pfam03358,FMN_red, NADPH-dependent FMN reductase. thiE: thiamine-phosphate pyrophosphorylas; Function unclear; putative reductase 3238887..3239504 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174155 YP_001223660.1 CDS CMM_2915 NC_009480.1 3239594 3240769 R putative Zn-dependant dehydrogenase (NP_737735.1| putative glutathione-dependent aldehyde dehydrogenase [Corynebacterium efficiens YS-314]; NP_962197.1| hypothetical protein MAP3263c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Function unclear; putative Zn-dependent dehydrogenase complement(3239594..3240769) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175164 YP_001223661.1 CDS CMM_2916 NC_009480.1 3241144 3241494 R hypothetical protein complement(3241144..3241494) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174411 YP_001223662.1 CDS CMM_2917 NC_009480.1 3241651 3241974 R hypothetical protein (YP_062476.1| hypothetical protein Lxx15660 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein complement(3241651..3241974) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175800 YP_001223663.1 CDS CMM_2918 NC_009480.1 3242226 3242429 D hypothetical protein 3242226..3242429 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175265 YP_001223664.1 CDS deoC NC_009480.1 3242535 3243257 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 3242535..3243257 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175971 YP_001223665.1 CDS CMM_2920 NC_009480.1 3243257 3244552 D catalyzes the removal of amino acids from the N termini of peptides; putative aminopeptidase 2 3243257..3244552 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173946 YP_001223666.1 CDS CMM_2921 NC_009480.1 3244634 3245347 R conserved hypothetical protein (NP_825954.1| hypothetical protein SAV4777 [Streptomyces avermitilis MA-4680]; AAS20121.1| hypothetical protein [Arthrobacter aurescens]). pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function.; hypothetical protein complement(3244634..3245347) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175705 YP_001223667.1 CDS CMM_2922 NC_009480.1 3245403 3246053 D conserved hypothetical protein, putative dienelactone hydrolase (P46209|USF_AQUPY USF PROTEIN [Aquifex pyrophilus]; ZP_00211570.1| COG0412: Dienelactone hydrolase and related enzymes [Burkholderia cepacia R18194]). pfam01738, DLH, Dienelactone hydrolase family.; Family membership; putative dienelactone hydrolase 3245403..3246053 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173876 YP_001223668.1 CDS CMM_2923 NC_009480.1 3246154 3246573 D hypothetical membrane protein (YP_063203.1| hypothetical protein Lxx24840 [Leifsonia xyli subsp. xyli str. CTCB07]; YP_120716.1| hypothetical protein nfa45010 [Nocardia farcinica IFM 10152]).; hypothetical protein 3246154..3246573 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175370 YP_001223669.1 CDS CMM_2924 NC_009480.1 3246688 3247383 D Hypothetical protein; hypothetical protein 3246688..3247383 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173373 YP_001223670.1 CDS CMM_2925 NC_009480.1 3247415 3248716 R conserved hypothetical protein, putative helicase (NP_813041.1| putative helicase [Bacteroides thetaiotaomicron VPI-5482]; NP_904413.1| TPR domain protein [Porphyromonas gingivalis W83]). cd00009, AAA, AAA-superfamily of ATPases associated with a wide variety of cellular activities, including membrane fusion,proteolysis, and DNA replication.; Family membership; putative helicase complement(3247415..3248716) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172999 YP_001223671.1 CDS CMM_2926 NC_009480.1 3248847 3249866 D hypothetical protein (YP_063208.1| hypothetical protein Lxx24950 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 3248847..3249866 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174134 YP_001223672.1 CDS CMM_2927 NC_009480.1 3249982 3250410 D conserved hypothetical protein (YP_119319.1| hypothetical protein nfa31080 [Nocardia farcinica IFM 10152]; NP_631048.1| conserved hypothetical protein SC8F11.09. [Streptomyces coelicolor A3(2)]). pfam00903,Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; hypothetical protein 3249982..3250410 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173848 YP_001223673.1 CDS fecE NC_009480.1 3250434 3251276 R putative iron-siderophore ABC transporter, ATP-binding protein (NP_827669.1| putative iron(III) dicitrate transport system ATP-binding protein [Streptomyces avermitilis MA-4680]; ZP_00292631.1| COG1120: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Thermobifida fusca]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative iron-siderophore ABC transporter ATP-binding protein complement(3250434..3251276) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175678 YP_001223674.1 CDS fecD2 NC_009480.1 3251311 3252417 R putative iron-siderophore ABC transporter, permease component (NP_396248.1| AGR_pAT_451p [Agrobacterium tumefaciens str. C58]; CAF19213.1| cobalamin/Fe3+-siderophores transport system, permease component [Corynebacterium glutamicum ATCC 13032]). , pfam01032,FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.; Specificity unclear; putative iron-siderophore ABC transporterpermease complement(3251311..3252417) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173270 YP_001223675.1 CDS fecC2 NC_009480.1 3252414 3253472 R putative iron-siderophore ABC transporter, permease component (NP_535686.1| ABC transporter, membrane spanning protein [iron] [Agrobacterium tumefaciens str. C58]; CAF19214.1| cobalamin/ Fe3+-siderophores transport system,permease component [Corynebacterium glutamicum ATCC 13032]). , pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.; Specificity unclear; putative iron-siderophore ABC transporterpermease complement(3252414..3253472) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173214 YP_001223676.1 CDS fecB2 NC_009480.1 3253575 3254579 D putative iron-siderophore ABC transporter,substrate-binding protein (CAF19960.1| ABC-type cobalamin/Fe3+-siderophores transport system secreted component [Corynebacterium glutamicum ATCC 13032]; NP_789016.1| putative iron-siderophore binding lipoprotein [Tropheryma whipplei TW08/27]). , pfam01497, Peripla_BP_2,Periplasmic binding protein. This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport. InterPro: Periplasmic binding protein.; Specificity unclear; putative iron-siderophore ABC transportersubstrate-binding protein 3253575..3254579 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173175 YP_001223677.1 CDS CMM_2932 NC_009480.1 3254708 3255382 D conserved membrane protein (ZP_00135206.2| COG0477: Permeases of the major facilitator superfamily [Actinobacillus pleuropneumoniae serovar 1 str. 4074]; AAO81566.1| conserved hypothetical protein [Enterococcus faecalis V583]).; hypothetical protein 3254708..3255382 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173013 YP_001223678.1 CDS CMM_2933 NC_009480.1 3255416 3257395 R conserved membrane protein, putative copper export protein (YP_063209.1| hypothetical protein Lxx24960 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226005.1| COG3336: Predicted membrane protein [Kineococcus radiotolerans SRS30216]; ZP_00293713.1| COG3336: Predicted membrane protein [Thermobifida fusca]). two different domains. N-terminal: pfam05425, CopD, Copper resistance protein D; COG1276, PcoD, Putative copper export protein. C-terminal: COG3336 Predicted membrane protein.; Function unclear; putative copper export protein complement(3255416..3257395) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174751 YP_001223679.1 CDS hupB NC_009480.1 3257527 3257814 R putative DNA-binding protein HU (DNA-binding protein II) (YP_063210.1| DNA-binding HU protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787244.1| DNA-binding protein HU [Tropheryma whipplei str. Twist]; NP_826304.1| putative DNA-binding protein Hu 1 [Streptomyces avermitilis MA-4680]). pfam00216,Bac_DNA_binding, Bacterial DNA-binding protein.; Function unclear; putative DNA-binding protein HU complement(3257527..3257814) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173147 YP_001223680.1 CDS rpsN NC_009480.1 3257946 3258251 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(3257946..3258251) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174512 YP_001223681.1 CDS rpmG NC_009480.1 3258254 3258421 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(3258254..3258421) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173972 YP_001223682.1 CDS rpmB NC_009480.1 3258421 3258657 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(3258421..3258657) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175336 YP_001223683.1 CDS furB NC_009480.1 3258872 3259321 R putative ferric uptake regulator, Fur family (YP_063214.1| ferric uptake regulator, Fur family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696299.1| probable metal uptake regulator; Specificity unclear; ferric uptake regulator family protein complement(3258872..3259321) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174934 YP_001223684.1 CDS CMM_2939 NC_009480.1 3259318 3260244 R putative metal ABC transporter, permease component (YP_063215.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055329.1| ABC-type transporter, permease components [Propionibacterium acnes KPA171202]). pfam00950, ABC-3, ABC 3 transport family.; Specificity unclear; putative metal ABC transporter permease complement(3259318..3260244) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174337 YP_001223685.1 CDS CMM_2940 NC_009480.1 3260241 3261116 R putative metal ABC transporter, ATP-binding protein (YP_063216.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_116650.1| putative ABC transporter ATP-binding protein [Nocardia farcinica IFM 10152]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative metal ABC transporter ATP-binding protein complement(3260241..3261116) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175257 YP_001223686.1 CDS CMM_2941 NC_009480.1 3261113 3262066 R putative metal ABC transporter, substrate-binding protein (YP_063217.1| ABC transporter, solute binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055331.1| solute binding protein [Propionibacterium acnes KPA171202]). pfam01297, SBP_bac_9, Periplasmic solute binding protein family.; Specificity unclear; putative metal ABC transporter substrate-binding protein complement(3261113..3262066) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174474 YP_001223687.1 CDS CMM_2942 NC_009480.1 3262136 3263536 R putative 2-keto-acid dehydrogenase,dihydrolipoamide acetyltransferase E2 component (YP_063218.1| dihydrolipoamide acyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825555.1| putative dihydrolipoamide acyltransferase component [Streptomyces avermitilis MA-4680]). pfam00364, Biotin_lipoyl, Biotin-requiring enzyme. pfam02817, E3_binding, e3 binding domain. This family represents a small domain of the E2 subunit of 2-oxo-acid dehydrogenases responsible for the binding of the E3 subunit. pfam00198, 2-oxoacid_dh, 2-oxoacid dehydrogenases acyltransferase (catalytic domain). These proteins contain one to three copies of a lipoyl binding domain followed by the catalytic domain.; Specificity unclear; branched-chain alpha-keto acid dehydrogenase subunit E2 complement(3262136..3263536) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174283 YP_001223688.1 CDS CMM_2943 NC_009480.1 3263577 3264632 R putative 2-keto acid dehydrogenase, dehydrogenase E1 beta component (YP_063219.1| pyruvate dehydrogenase E1 component, beta subunit [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628005.1| putative branched-chain alpha keto acid dehydrogenase E1 beta subunit [Streptomyces coelicolor A3(2)]). pfam02779, Transket_pyr,Transketolase, pyridine binding domain. pfam02780,Transketolase_C, Transketolase, C-terminal domain. The C-terminal domain of transketolase has been proposed as a regulatory molecule binding site. InterPro: Transketolase.; Specificity unclear; putative 2-keto acid dehydrogenase,dehydrogenase E1 beta component complement(3263577..3264632) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173597 YP_001223689.1 CDS CMM_2944 NC_009480.1 3264629 3265741 R putative 2-keto acid dehydrogenase, dehydrogenase E1 beta component (YP_063220.1| pyruvate dehydrogenase E1 component, alpha subunit [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628006.1| putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit [Streptomyces coelicolor A3(2)]). , pfam00676, E1_dh, Dehydrogenase E1 component. This family uses thiamine pyrophosphate as a cofactor.; Specificity unclear; putative 2-keto acid dehydrogenase,dehydrogenase E1 beta component complement(3264629..3265741) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175714 YP_001223690.1 CDS hisC2 NC_009480.1 3265751 3266866 R putative histidinol-phosphate aminotransferase 2 (YP_063221.1| histidinol-phosphate aminotransferase 2 [Leifsonia xyli subsp. xyli str. CTCB07]; Q82FJ1|PATR_STRAW Putative phenylalanine aminotransferase). pfam00155, Aminotran_1_2,Aminotransferase class I and II.; Specificity unclear; putative aminotransferase complement(3265751..3266866) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174774 YP_001223691.1 CDS CMM_2946 NC_009480.1 3266937 3267332 D conserved membrane protein (YP_063222.1| hypothetical protein Lxx25090 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293541.1| COG1950: Predicted membrane protein [Thermobifida fusca]). pfam04020, DUF360, Membrane protein of unknown function.; Conserved hypothetical protein; hypothetical protein 3266937..3267332 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173605 YP_001223692.1 CDS CMM_2947 NC_009480.1 3267341 3268615 R hypothetical protein gidA: glucose-inhibited division protein; hypothetical protein complement(3267341..3268615) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174893 YP_001223693.1 CDS CMM_2948 NC_009480.1 3268612 3268938 R hypothetical protein complement(3268612..3268938) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175092 YP_001223694.1 CDS CMM_2949 NC_009480.1 3269071 3269598 D putative protein-tyrosine-phosphatase (Small acidic phosphotyrosine protein phosphatase) (P53433|PTPA_STRCO Low molecular weight protein-tyrosine-phosphatase (PTPase) (Small, acidic phosphotyrosine protein phosphatase); ZP_00292310.1| COG0394: Protein-tyrosine- phosphatase [Thermobifida fusca]). pfam01451, LMWPc, Low molecular weight phosphotyrosine protein phosphatase.; Function unclear; putative protein-tyrosine-phosphatase 3269071..3269598 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175727 YP_001223695.1 CDS purB NC_009480.1 3269612 3270994 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 3269612..3270994 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174863 YP_001223696.1 CDS CMM_2951 NC_009480.1 3271053 3271322 R hypothetical membrane protein (YP_063224.1| hypothetical protein Lxx25110 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787867.1| hypothetical protein TWT739 [Tropheryma whipplei str. Twist]).; hypothetical protein complement(3271053..3271322) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173229 YP_001223697.1 CDS CMM_2952 NC_009480.1 3271325 3271981 R conserved membrane protein (ZP_00347695.1| COG3247: Uncharacterized conserved protein [Pseudomonas aeruginosa UCBPP-PA14]; NP_879989.1| putative membrane protein [Bordetella pertussis Tohama I]).; Conserved hypothetical protein; hypothetical protein complement(3271325..3271981) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174118 YP_001223698.1 CDS ppgK2 NC_009480.1 3272339 3273223 D putative polyphosphate glucokinase (Polyphosphate-glucose phosphotransferase) (YP_061973.1| glucokinase [Leifsonia xyli subsp. xyli str. CTCB07]; BAC84981.1| polyphosphate-dependent glucokinase [Microlunatus phosphovorus]). , pfam00480, ROK, ROK family.; High confidence in function and specificity; putative polyphosphate glucokinase 3272339..3273223 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173253 YP_001223699.1 CDS CMM_2954 NC_009480.1 3273314 3274429 D putative glycerate kinase (YP_061712.1| glycerate kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_931292.1| Glycerate kinase 2 [Photorhabdus luminescens subsp. laumondii TTO1]). pfam02595, Gly_kinase, Glycerate kinase family.; High confidence in function and specificity; putative glycerate kinase 3273314..3274429 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175939 YP_001223700.1 CDS CMM_2955 NC_009480.1 3274446 3275672 R putative glycosyl transferase (NP_789728.1| putative glycosyltransferase [Tropheryma whipplei TW08/27]; ZP_00058815.1| COG0438: Glycosyltransferase [Thermobifida fusca]). , pfam00534, Glycos_transf_1,Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates,including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP,ADP, GDP or CMP linked sugars. InterPro: Glycosyl transferases group 1.; Function unclear; putative glycosyl transferase complement(3274446..3275672) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175601 YP_001223701.1 CDS CMM_2956 NC_009480.1 3275841 3276230 D putative transcriptional regulator, MerR family (ZP_00225271.3| COG0789: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]; NP_627487.1| putative merR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00376,MerR, MerR family regulatory protein.; Hypothetical protein; hypothetical protein 3275841..3276230 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175452 YP_001223702.1 CDS prfC NC_009480.1 3276287 3277912 D putative peptide chain release factor 3 (RF-3)(YP_121111.1| putative peptide chain release factor [Nocardia farcinica IFM 10152]; ZP_00292654.1| COG4108: Peptide chain release factor RF-3 [Thermobifida fusca]). pfam00009, GTP_EFTU, Elongation factor Tu GTP binding domain. pfam03144, GTP_EFTU_D2, Elongation factor Tu domain 2.; High confidence in function and specificity; putative peptide chain release factor 3 3276287..3277912 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173932 YP_001223703.1 CDS CMM_2958 NC_009480.1 3278067 3278372 D conserved hypothetical protein (YP_062896.1| hypothetical protein Lxx20930 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_691705.1| hypothetical protein OB0784 [Oceanobacillus iheyensis HTE831]; NP_738809.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam05495, zf-CHY, CHY zinc finger. This family of domains are likely to bind to zinc ions. They contain many conserved cysteine and histidine residues. We have named this domain after the N-terminal motif CXHY.; Function unclear; hypothetical protein 3278067..3278372 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173866 YP_001223704.1 CDS dnaB NC_009480.1 3278482 3279861 R putative replicative DNA helicase (YP_063226.1| replicative DNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628097.1| putative replicative DNA helicase [Streptomyces coelicolor A3(2)]). pfam00772, DnaB, DnaB-like helicase N terminal domain. pfam03796, DnaB_C, DnaB-like helicase C terminal domain. InterPro: DnaB helicase.; High confidence in function and specificity; putative replicative DNA helicase complement(3278482..3279861) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174719 YP_001223705.1 CDS rplI NC_009480.1 3280318 3280770 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(3280318..3280770) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175453 YP_001223706.1 CDS rpsR NC_009480.1 3280782 3281045 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(3280782..3281045) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174555 YP_001223707.1 CDS ssb NC_009480.1 3281082 3281633 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(3281082..3281633) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175849 YP_001223708.1 CDS rpsF NC_009480.1 3281637 3282101 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(3281637..3282101) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175696 YP_001223709.1 CDS pcnA NC_009480.1 3282265 3283695 R putative tRNA nucleotidyltransferase/ poly(A)nucleotidyltransferase (YP_063231.1| poly(A) polymerase; tRNA nucleotidyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825476.1| putative RNA nucleotidyltransferase [Streptomyces avermitilis MA-4680]; NP_787928.1| poly(A) polymerase [Tropheryma whipplei str. Twist]). pfam01743, PolyA_pol, Poly A polymerase family. This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase,which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. pfam01966,HD, HD domain. HD domains are metal dependent phosphohydrolases.; Specificity unclear; putative RNA nucleotidyltransferase complement(3282265..3283695) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173088 YP_001223710.1 CDS CMM_2965 NC_009480.1 3283789 3286086 D conserved hypothetical protein (YP_063232.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291602.1| hypothetical protein Tfus02002926 [Thermobifida fusca]); hypothetical protein 3283789..3286086 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175572 YP_001223711.1 CDS CMM_2966 NC_009480.1 3286123 3287751 D conserved membrane protein, MOP family (YP_063233.1| hypothetical protein Lxx25210 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789730.1| conserved integral membrane protein (possible virulence factor)[Tropheryma whipplei TW08/27]). pfam03023, MVIN,MviN-like protein.; Function unclear; MOP family membrane protein 3286123..3287751 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175409 YP_001223712.1 CDS trxB1 NC_009480.1 3287908 3288945 D putative thioredoxin reductase (YP_063234.1| thioredoxin-disulfide reductase [Leifsonia xyli subsp. xyli str. CTCB07]; Q05741|TRXB_STRCL Thioredoxin reductase (TRXR)). , pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase.; High confidence in function and specificity; putative thioredoxin reductase 3287908..3288945 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174874 YP_001223713.1 CDS trxA NC_009480.1 3289013 3289336 D putative thioredoxin (YP_063235.1| thioredoxin [Leifsonia xyli subsp. xyli str. CTCB07]; Q05739|THIO_STRCL Thioredoxin (TRX)). pfam00085,Thioredoxin, Thioredoxin. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond.; High confidence in function and specificity; putative thioredoxin 3289013..3289336 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175941 YP_001223714.1 CDS CMM_2969 NC_009480.1 3289507 3290829 D putative transcriptional regulator containing an aminotransferase domain (YP_063236.1| valine-pyruvate aminotransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00294408.1| COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Thermobifida fusca]). pfam00155, Aminotran_1_2,Aminotransferase class I and II.; Function unclear; transcriptional regulator 3289507..3290829 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174325 YP_001223715.1 CDS ddlB NC_009480.1 3290873 3291838 D putative D-alanine-D-alanine ligase (D-alanylalanine synthetase) (ZP_00057905.1| COG1181: D-alanine-D-alanine ligase and related ATP-grasp enzymes [Thermobifida fusca]; O66806|DDL_AQUAE D-alanine--D-alanine ligase (D-alanylalanine synthetase)(D-Ala-D-Ala ligase)). pfam01820, Dala_Dala_ligas, D-ala D-ala ligase. This family contains D-alanine--D-alanine ligase enzymes EC:6.3.2.4. InterPro: D-alanine--D-alanine ligase.; High confidence in function and specificity; putative D-alanine-D-alanine ligase 3290873..3291838 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174665 YP_001223716.1 CDS parB1 NC_009480.1 3291891 3292880 R putative chromosome partitioning protein (YP_063237.1| chromosome partitioning protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_302727.1| putative cell division protein [Mycobacterium leprae TN]). pfam02195,ParBc, ParB-like nuclease domain. , InterPro: ParB-like partition protein.; High confidence in function and specificity; putative chromosome partitioning protein complement(3291891..3292880) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175168 YP_001223717.1 CDS parA NC_009480.1 3292880 3293761 R putative chromosome partitioning protein (YP_063238.1| chromosome partitioning protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825486.1| putative partitioning or sporulation protein [Streptomyces avermitilis MA-4680]). pfam00991, ParA, ParA family ATPase. InterPro: ParA family ATPase.; High confidence in function and specificity; putative chromosome partitioning protein complement(3292880..3293761) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175456 YP_001223718.1 CDS gidB NC_009480.1 3293912 3294547 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(3293912..3294547) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175446 YP_001223719.1 CDS CMM_2974 NC_009480.1 3295096 3295653 R putative DNA/RNA binding protein (YP_063240.1| hypothetical protein Lxx25260 [Leifsonia xyli subsp. xyli str. CTCB07]; AAK48405.1| R3H domain-containing protein [Mycobacterium tuberculosis CDC1551]). pfam01424, R3H, R3H domain. The function of the domain is predicted to be binding ssDNA. InterPro: R3H domain.; Function unclear; putative DNA/RNA binding protein complement(3295096..3295653) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173460 YP_001223720.1 CDS CMM_2975 NC_009480.1 3295650 3296612 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC complement(3295650..3296612) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174770 YP_001223721.1 CDS CMM_2976 NC_009480.1 3296623 3296934 R conserved hypothetical protein (YP_063242.1| alpha-hemolysin [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825490.1| hypothetical protein SAV4313 [Streptomyces avermitilis MA-4680]). pfam01809, DUF37, Domain of unknown function DUF37. This domain is found in short (70 amino acid) hypothetical proteins from various bacteria.; hypothetical protein complement(3296623..3296934) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173584 YP_001223722.1 CDS rnpA NC_009480.1 3296931 3297272 R putative RNAse P, protein component (Q50789|RNPA_MYCTU Ribonuclease P protein component (RNaseP protein) (RNase P protein)(Protein C5); NP_602290.1| RNase P protein component [Corynebacterium glutamicum ATCC 13032]). pfam00825, Ribonuclease_P,Ribonuclease P.; High confidence in function and specificity; putative RNAse P, protein component complement(3296931..3297272) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174634 YP_001223723.1 CDS rpmH NC_009480.1 3297276 3297413 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(3297276..3297413) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173031 CMM_tRNA_0001 tRNA CMM_tRNA_0001 NC_009480.1 11222 11298 D tRNA-Ile 11222..11298 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174467 CMM_tRNA_0002 tRNA CMM_tRNA_0002 NC_009480.1 11379 11451 D tRNA-Ala 11379..11451 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172956 CMM_tRNA_0003 tRNA CMM_tRNA_0003 NC_009480.1 25622 25708 D tRNA-Leu 25622..25708 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5172972 CMM_tRNA_0004 tRNA CMM_tRNA_0004 NC_009480.1 602300 602387 D tRNA-Ser 602300..602387 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173444 CMM_tRNA_0005 tRNA CMM_tRNA_0005 NC_009480.1 604058 604149 D tRNA-Ser 604058..604149 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174152 CMM_tRNA_0006 tRNA CMM_tRNA_0006 NC_009480.1 609908 609980 D tRNA-Arg 609908..609980 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175501 CMM_tRNA_0007 tRNA CMM_tRNA_0007 NC_009480.1 958577 958652 R tRNA-Phe complement(958577..958652) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174258 CMM_tRNA_0008 tRNA CMM_tRNA_0008 NC_009480.1 958722 958798 R tRNA-Asp complement(958722..958798) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173594 CMM_tRNA_0009 tRNA CMM_tRNA_0009 NC_009480.1 958820 958895 R tRNA-Glu complement(958820..958895) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173509 CMM_tRNA_0010 tRNA CMM_tRNA_0010 NC_009480.1 1018250 1018337 R tRNA-Ser complement(1018250..1018337) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173245 CMM_tRNA_0011 tRNA CMM_tRNA_0011 NC_009480.1 1055698 1055771 R tRNA-Pro complement(1055698..1055771) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173528 CMM_tRNA_0012 tRNA CMM_tRNA_0012 NC_009480.1 1072979 1073054 D tRNA-Thr 1072979..1073054 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173665 CMM_tRNA_0013 tRNA CMM_tRNA_0013 NC_009480.1 1219040 1219115 D tRNA-Lys 1219040..1219115 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174007 CMM_tRNA_0014 tRNA CMM_tRNA_0014 NC_009480.1 1270326 1270397 D tRNA-Gln 1270326..1270397 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175218 CMM_tRNA_0015 tRNA CMM_tRNA_0015 NC_009480.1 1281203 1281278 D tRNA-Glu 1281203..1281278 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175835 CMM_tRNA_0016 tRNA CMM_tRNA_0016 NC_009480.1 1304816 1304887 D tRNA-Arg 1304816..1304887 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173755 CMM_tRNA_0017 tRNA CMM_tRNA_0017 NC_009480.1 1377056 1377132 D tRNA-Met 1377056..1377132 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174735 CMM_tRNA_0018 tRNA CMM_tRNA_0018 NC_009480.1 1472248 1472332 R tRNA-Leu complement(1472248..1472332) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173816 CMM_tRNA_0019 tRNA CMM_tRNA_0019 NC_009480.1 1632234 1632309 R tRNA-His complement(1632234..1632309) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174519 CMM_tRNA_0020 tRNA CMM_tRNA_0020 NC_009480.1 1633626 1633701 D tRNA-Arg 1633626..1633701 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174420 CMM_tRNA_0021 tRNA CMM_tRNA_0021 NC_009480.1 1655431 1655504 R tRNA-Gly complement(1655431..1655504) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174879 CMM_tRNA_0022 tRNA CMM_tRNA_0022 NC_009480.1 1655696 1655771 D tRNA-Pro 1655696..1655771 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175030 CMM_tRNA_0023 tRNA CMM_tRNA_0023 NC_009480.1 1697559 1697634 D tRNA-Ala 1697559..1697634 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175956 CMM_tRNA_0024 tRNA CMM_tRNA_0024 NC_009480.1 1805904 1805979 R tRNA-Asn complement(1805904..1805979) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174315 CMM_tRNA_0025 tRNA CMM_tRNA_0025 NC_009480.1 1809026 1809099 D tRNA-Met 1809026..1809099 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175533 CMM_tRNA_0026 tRNA CMM_tRNA_0026 NC_009480.1 1838068 1838143 D tRNA-Val 1838068..1838143 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174110 CMM_tRNA_0027 tRNA CMM_tRNA_0027 NC_009480.1 1922019 1922104 D tRNA-Leu 1922019..1922104 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174117 CMM_tRNA_0028 tRNA CMM_tRNA_0028 NC_009480.1 1990115 1990200 D tRNA-Leu 1990115..1990200 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174972 CMM_tRNA_0029 tRNA CMM_tRNA_0029 NC_009480.1 2060091 2060165 R tRNA-Val complement(2060091..2060165) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173992 CMM_tRNA_0030 tRNA CMM_tRNA_0030 NC_009480.1 2060176 2060249 R tRNA-Cys complement(2060176..2060249) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174549 CMM_tRNA_0031 tRNA CMM_tRNA_0031 NC_009480.1 2060311 2060385 R tRNA-Gly complement(2060311..2060385) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173862 CMM_tRNA_0032 tRNA CMM_tRNA_0032 NC_009480.1 2060666 2060741 D tRNA-Val 2060666..2060741 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174129 CMM_tRNA_0033 tRNA CMM_tRNA_0033 NC_009480.1 2228446 2228519 R tRNA-Pro complement(2228446..2228519) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175440 CMM_tRNA_0034 tRNA CMM_tRNA_0034 NC_009480.1 2555753 2555830 R tRNA-Leu complement(2555753..2555830) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175152 CMM_tRNA_0035 tRNA CMM_tRNA_0035 NC_009480.1 2577446 2577520 R tRNA-Gln complement(2577446..2577520) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175884 CMM_tRNA_0036 tRNA CMM_tRNA_0036 NC_009480.1 2755189 2755264 R tRNA-Ala complement(2755189..2755264) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173545 CMM_tRNA_0037 tRNA CMM_tRNA_0037 NC_009480.1 2763910 2763981 D tRNA-Arg 2763910..2763981 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173794 CMM_tRNA_0038 tRNA CMM_tRNA_0038 NC_009480.1 2798325 2798397 R tRNA-Thr complement(2798325..2798397) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175708 CMM_tRNA_0039 tRNA CMM_tRNA_0039 NC_009480.1 2827156 2827231 D tRNA-Lys 2827156..2827231 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175523 CMM_tRNA_0040 tRNA CMM_tRNA_0040 NC_009480.1 3072543 3072632 R tRNA-Ser complement(3072543..3072632) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174729 CMM_tRNA_0041 tRNA CMM_tRNA_0041 NC_009480.1 3118409 3118484 R tRNA-Trp complement(3118409..3118484) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5173165 CMM_tRNA_0042 tRNA CMM_tRNA_0042 NC_009480.1 3122985 3123058 R tRNA-Met complement(3122985..3123058) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175531 CMM_tRNA_0043 tRNA CMM_tRNA_0043 NC_009480.1 3123098 3123172 R tRNA-Thr complement(3123098..3123172) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175703 CMM_tRNA_0044 tRNA CMM_tRNA_0044 NC_009480.1 3130370 3130454 R tRNA-Tyr complement(3130370..3130454) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175192 CMM_tRNA_0045 tRNA CMM_tRNA_0045 NC_009480.1 3224558 3224631 D tRNA-Gly 3224558..3224631 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175470 CMM_RNA_0001 rRNA CMM_RNA_0001 NC_009480.1 2247692 2247815 R 5S ribosomal RNA complement(2247692..2247815) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5174502 CMM_rRNA_0004 rRNA CMM_rRNA_0004 NC_009480.1 2247934 2251046 R 23S ribosomal RNA complement(join(2247934..2249439,2249514..2251046)) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5714854 CMM_RNA_0001a rRNA CMM_RNA_0001a NC_009480.1 2251470 2252999 R 16S ribosomal RNA complement(2251470..2252999) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5309727 CMM_RNA_0002 rRNA CMM_RNA_0002 NC_009480.1 2868024 2868147 R 5S ribosomal RNA complement(2868024..2868147) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5175249 CMM_rRNA_0003 rRNA CMM_rRNA_0003 NC_009480.1 2868266 2871378 R 23S ribosomal RNA complement(join(2868266..2869771,2869847..2871378)) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5714853 CMM_RNA_0002a rRNA CMM_RNA_0002a NC_009480.1 2871802 2873331 R 16S ribosomal RNA complement(2871802..2873331) Clavibacter michiganensis subsp. michiganensis NCPPB 382 5309728