-- dump date 20140619_041321 -- class Genbank::CDS -- table cds_note -- id note NP_660907.1 identified by match to PFAM protein family HMM PF02767 NP_660908.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. NP_660909.1 in Escherichia coli transcription of this gene is enhanced by polyamines NP_660910.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates NP_660912.1 identified by match to PFAM protein family HMM PF02096 NP_660913.1 identified by match to PFAM protein family HMM PF01569 NP_660914.1 identified by match to PFAM protein family HMM PF00480 NP_660915.1 identified by match to PFAM protein family HMM PF01938 NP_660916.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity NP_660917.1 transforms a conserved lysine residue of initiation factor 5A into deoxyhypusine NP_660919.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_660920.1 identified by match to PFAM protein family HMM PF00702 NP_660921.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase NP_660922.1 identified by match to TIGR protein family HMM TIGR00125 NP_660924.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex NP_660925.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. NP_660926.1 identified by match to PFAM protein family HMM PF00137 NP_660927.2 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit A is part of the membrane proton channel F0 NP_660930.1 identified by match to PFAM protein family HMM PF01370 NP_660935.1 identified by match to PFAM protein family HMM PF02550 NP_660936.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function NP_660937.1 identified by match to PFAM protein family HMM PF02491 NP_660938.1 similar to PID:2209033; identified by sequence similarity NP_660939.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis NP_660940.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis NP_660941.1 identified by match to PFAM protein family HMM PF01098 NP_660942.1 identified by match to PFAM protein family HMM PF01225 NP_660943.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NP_660944.1 identified by match to PFAM protein family HMM PF01225 NP_660945.1 identified by match to PFAM protein family HMM PF01225 NP_660946.1 identified by match to PFAM protein family HMM PF00905 NP_660949.1 MraZ; UPF0040; crystal structure shows similarity to AbrB NP_660952.1 identified by match to PFAM protein family HMM PF00501 NP_660953.1 identified by match to PFAM protein family HMM PF00202 NP_660954.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium NP_660955.1 similar to GB:J04423 SP:P12999 PID:145427 PID:490221 GB:U00096; identified by sequence similarity NP_660957.1 identified by match to PFAM protein family HMM PF00155 NP_660958.1 identified by match to PFAM protein family HMM PF01792 NP_660959.1 identified by match to PFAM protein family HMM PF01317 NP_660960.1 identified by match to PFAM protein family HMM PF01520 NP_660961.1 identified by match to PFAM protein family HMM PF01131 NP_660962.1 identified by match to PFAM protein family HMM PF01638 NP_660963.1 similar to SP:P33649 PID:414746 PID:606343 GB:U00096 PID:1789812; identified by sequence similarity NP_660964.1 identified by match to PFAM protein family HMM PF01230 NP_660970.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity NP_660972.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_660973.1 similar to GB:U07174 PID:463911 PID:463912 PID:463913; identified by sequence similarity NP_660976.1 identified by match to PFAM protein family HMM PF00266 NP_660979.1 identified by match to PFAM protein family HMM PF00034 NP_660981.1 identified by match to PFAM protein family HMM PF00034 NP_660983.1 identified by match to PFAM protein family HMM PF01089 NP_660985.1 identified by match to PFAM protein family HMM PF03009 NP_660989.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate NP_660990.1 identified by match to PFAM protein family HMM PF02153 NP_660994.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis NP_660996.1 identified by match to PFAM protein family HMM PF00933 NP_660997.1 identified by match to PFAM protein family HMM PF00300 NP_660998.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate NP_661000.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis NP_661001.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive NP_661003.1 identified by match to PFAM protein family HMM PF00877 NP_661004.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype NP_661005.1 identified by match to PFAM protein family HMM PF02541 NP_661009.1 identified by match to PFAM protein family HMM PF01641 NP_661010.1 identified by match to PFAM protein family HMM PF00083 NP_661011.1 identified by match to PFAM protein family HMM PF00529 NP_661012.1 identified by match to PFAM protein family HMM PF00582 NP_661013.1 identified by match to PFAM protein family HMM PF02321 NP_661014.1 identified by match to PFAM protein family HMM PF00004 NP_661016.1 identified by match to PFAM protein family HMM PF00155 NP_661019.1 Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. NP_661022.1 identified by match to PFAM protein family HMM PF02374 NP_661026.1 identified by match to PFAM protein family HMM PF00881 NP_661027.1 identified by match to PFAM protein family HMM PF02080 NP_661029.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 NP_661030.1 identified by match to PFAM protein family HMM PF00595 NP_661031.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate NP_661032.1 catalyzes the hydrolysis of acylphosphate NP_661033.1 identified by match to PFAM protein family HMM PF00004 NP_661036.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NP_661038.1 identified by match to PFAM protein family HMM PF00076 NP_661039.1 identified by match to PFAM protein family HMM PF00909 NP_661040.1 identified by match to PFAM protein family HMM PF00543 NP_661044.1 identified by match to PFAM protein family HMM PF02367 NP_661046.1 identified by match to PFAM protein family HMM PF02410 NP_661047.1 identified by match to PFAM protein family HMM PF00521 NP_661048.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer NP_661050.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_661051.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_661053.1 identified by match to TIGR protein family HMM TIGR00612 NP_661054.1 identified by match to PFAM protein family HMM PF00106 NP_661055.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force NP_661056.1 identified by match to PFAM protein family HMM PF00467 NP_661057.1 binds directly to 23S ribosomal RNA NP_661058.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA NP_661059.2 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit NP_661060.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors NP_661061.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme NP_661062.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter NP_661063.1 identified by match to PFAM protein family HMM PF00289 NP_661064.1 identified by match to PFAM protein family HMM PF00364 NP_661065.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_661066.1 identified by match to PFAM protein family HMM PF00216 NP_661067.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein NP_661068.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin NP_661069.1 identified by match to PFAM protein family HMM PF01558 NP_661072.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_661074.1 identified by match to PFAM protein family HMM PF00037 NP_661075.1 identified by match to PFAM protein family HMM PF00106 NP_661078.1 identified by match to PFAM protein family HMM PF01040 NP_661079.1 identified by match to PFAM protein family HMM PF00702 NP_661081.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway NP_661082.1 identified by match to PFAM protein family HMM PF00905 NP_661083.1 identified by match to PFAM protein family HMM PF00561 NP_661084.1 identified by match to PFAM protein family HMM PF00597 NP_661086.1 identified by match to PFAM protein family HMM PF01593 NP_661089.1 identified by match to PFAM protein family HMM PF01061 NP_661090.1 identified by match to PFAM protein family HMM PF00005 NP_661091.1 identified by match to PFAM protein family HMM PF00370 NP_661094.1 identified by match to Prosite PS00190 NP_661097.1 identified by match to PFAM protein family HMM PF00004 NP_661098.1 catalyzes the formation of L-tryptophan from indole and L-serine NP_661100.1 identified by match to PFAM protein family HMM PF00072 NP_661101.1 identified by match to PFAM protein family HMM PF00512 NP_661102.1 identified by match to PFAM protein family HMM PF00534 NP_661104.1 identified by match to PFAM protein family HMM PF00083 NP_661105.1 identified by match to TIGR protein family HMM TIGR00476 NP_661106.1 identified by match to PFAM protein family HMM PF00448 NP_661108.1 identified by match to PFAM protein family HMM PF01135 NP_661109.1 identified by match to PFAM protein family HMM PF00639 NP_661110.1 identified by match to PFAM protein family HMM PF00391 NP_661111.1 identified by match to PFAM protein family HMM PF00772 NP_661112.1 identified by match to PFAM protein family HMM PF03167 NP_661113.1 identified by match to PFAM protein family HMM PF02441 NP_661115.1 identified by match to PFAM protein family HMM PF01467 NP_661117.1 identified by match to PFAM protein family HMM PF03279 NP_661121.1 identified by match to PFAM protein family HMM PF00005 NP_661122.1 identified by match to PFAM protein family HMM PF00535 NP_661124.1 identified by match to PFAM protein family HMM PF00534 NP_661126.1 identified by match to PFAM protein family HMM PF01075 NP_661129.1 identified by match to PFAM protein family HMM PF00534 NP_661130.1 identified by match to PFAM protein family HMM PF00534 NP_661131.1 identified by match to PFAM protein family HMM PF00534 NP_661132.1 identified by match to PFAM protein family HMM PF00984 NP_661134.1 identified by match to PFAM protein family HMM PF01370 NP_661137.1 identified by match to PFAM protein family HMM PF01148 NP_661139.1 identified by match to PFAM protein family HMM PF00359 NP_661140.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG NP_661144.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination NP_661145.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NP_661146.1 identified by match to PFAM protein family HMM PF02033 NP_661147.1 identified by match to PFAM protein family HMM PF01509 NP_661148.1 identified by match to PFAM protein family HMM PF01687 NP_661149.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence NP_661151.1 Essential for recycling GMP and indirectly, cGMP NP_661153.1 identified by match to PFAM protein family HMM PF00903 NP_661154.1 identified by match to PFAM protein family HMM PF00365 NP_661155.1 identified by match to PFAM protein family HMM PF00483 NP_661156.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) NP_661158.1 similar to GB:M34854 SP:P31519 PID:155479; identified by sequence similarity NP_661159.1 identified by match to PFAM protein family HMM PF02481 NP_661160.1 identified by match to PFAM protein family HMM PF00348 NP_661161.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate NP_661163.1 identified by match to PFAM protein family HMM PF00005 NP_661164.1 identified by match to PFAM protein family HMM PF00408 NP_661165.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase NP_661166.1 plays an essential role in ATP-dependent branch migration of the Holliday junction NP_661167.1 identified by match to PFAM protein family HMM PF02875 NP_661168.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes NP_661170.1 identified by match to PFAM protein family HMM PF01103 NP_661171.1 identified by match to PFAM protein family HMM PF01255 NP_661172.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_661173.1 identified by match to PFAM protein family HMM PF00549 NP_661174.1 identified by match to PFAM protein family HMM PF00571 NP_661177.1 identified by match to PFAM protein family HMM PF01943 NP_661178.1 identified by match to PFAM protein family HMM PF00795 NP_661182.1 identified by match to PFAM protein family HMM PF00776 NP_661183.1 identified by match to PFAM protein family HMM PF00408 NP_661184.1 identified by match to PFAM protein family HMM PF02684 NP_661186.2 these proteins belong to a family of oxidoreductases related to the NADPH-dependent glutamate synthase NP_661187.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway NP_661188.1 converts L-glutamate to D-glutamate, a component of peptidoglycan NP_661189.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 NP_661190.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP NP_661192.2 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins NP_661193.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome NP_661194.1 identified by match to PFAM protein family HMM PF01098 NP_661197.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis NP_661199.1 identified by match to PFAM protein family HMM PF00216 NP_661201.1 identified by match to PFAM protein family HMM PF00004 NP_661203.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation NP_661205.1 similar to PID:1809122; identified by sequence similarity NP_661206.1 identified by match to PFAM protein family HMM PF00355 NP_661207.1 identified by match to PFAM protein family HMM PF00033 NP_661208.1 identified by match to PFAM protein family HMM PF00128 NP_661209.1 identified by match to PFAM protein family HMM PF00483 NP_661210.1 identified by match to PFAM protein family HMM PF00908 NP_661212.1 identified by match to PFAM protein family HMM PF01370 NP_661213.1 identified by match to PFAM protein family HMM PF00483 NP_661215.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) NP_661217.1 identified by match to PFAM protein family HMM PF00310 NP_661219.1 identified by match to PFAM protein family HMM PF02687 NP_661220.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues NP_661221.1 identified by match to PFAM protein family HMM PF00535 NP_661222.1 identified by match to PFAM protein family HMM PF02143 NP_661223.1 identified by match to PFAM protein family HMM PF00551 NP_661224.1 involved in de novo purine biosynthesis NP_661226.1 identified by match to PFAM protein family HMM PF00037 NP_661227.1 identified by match to PFAM protein family HMM PF00355 NP_661228.1 identified by sequence similarity NP_661229.1 identified by match to PFAM protein family HMM PF02470 NP_661230.1 identified by match to PFAM protein family HMM PF00005 NP_661233.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell NP_661234.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine NP_661235.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) NP_661237.1 death on curing protein; similar to SP:Q06259 PID:463277; identified by sequence similarity NP_661238.1 identified by match to PFAM protein family HMM PF00488 NP_661239.1 identified by match to PFAM protein family HMM PF01066 NP_661240.1 similar to GB:U00096 PID:1773102 PID:1786620 PID:2329841; identified by sequence similarity NP_661241.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate NP_661244.1 identified by match to PFAM protein family HMM PF00128 NP_661246.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction NP_661247.1 identified by match to PFAM protein family HMM PF00580 NP_661250.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys NP_661252.1 identified by match to PFAM protein family HMM PF02374 NP_661254.1 identified by match to PFAM protein family HMM PF00106 NP_661255.1 identified by match to TIGR protein family HMM TIGR00178 NP_661262.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate NP_661264.1 identified by match to PFAM protein family HMM PF01368 NP_661266.1 identified by match to PFAM protein family HMM PF00535 NP_661268.1 identified by match to PFAM protein family HMM PF01569 NP_661271.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine NP_661273.1 identified by match to PFAM protein family HMM PF00070 NP_661275.1 identified by match to PFAM protein family HMM PF00731 NP_661276.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_661277.1 identified by match to PFAM protein family HMM PF01408 NP_661278.1 identified by match to PFAM protein family HMM PF00893 NP_661279.1 identified by match to PFAM protein family HMM PF00005 NP_661280.1 identified by match to PFAM protein family HMM PF02321 NP_661282.1 identified by match to PFAM protein family HMM PF00005 NP_661284.1 catalyzes the interconversion of succinyl-CoA and succinate NP_661285.1 identified by match to PFAM protein family HMM PF00383 NP_661289.1 identified by match to PFAM protein family HMM PF00590 NP_661290.1 identified by match to PFAM protein family HMM PF00590 NP_661291.1 identified by match to PFAM protein family HMM PF00590 NP_661292.1 identified by match to PFAM protein family HMM PF00590 NP_661294.1 identified by match to PFAM protein family HMM PF00590 NP_661295.1 identified by match to PFAM protein family HMM PF00005 NP_661296.1 identified by match to PFAM protein family HMM PF02361 NP_661297.1 periplasmic cobalt binding component of the cobalt transport system NP_661298.2 catalyzes the ATP-dependent transport of cobalt NP_661303.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate NP_661305.1 identified by match to PFAM protein family HMM PF01493 NP_661306.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate NP_661308.1 binds and unfolds substrates as part of the ClpXP protease NP_661313.1 identified by match to PFAM protein family HMM PF00037 NP_661314.1 identified by match to PFAM protein family HMM PF01497 NP_661315.1 identified by match to PFAM protein family HMM PF00003 NP_661316.1 identified by match to PFAM protein family HMM PF00005 NP_661319.1 identified by match to PFAM protein family HMM PF00795 NP_661321.1 identified by match to PFAM protein family HMM PF01444 NP_661322.1 identified by match to PFAM protein family HMM PF02514 NP_661324.1 identified by match to PFAM protein family HMM PF00092 NP_661325.1 identified by match to PFAM protein family HMM PF01078 NP_661326.1 identified by match to PFAM protein family HMM PF02514 NP_661328.1 identified by match to Interpro IPR001207 NP_661334.1 identified by match to PFAM protein family HMM PF00263 NP_661337.1 identified by match to PFAM protein family HMM PF00991 NP_661338.1 identified by match to PFAM protein family HMM PF00437 NP_661339.1 similar to GP:7208429; identified by sequence similarity NP_661340.1 similar to GP:5670332; identified by sequence similarity NP_661346.1 identified by match to PFAM protein family HMM PF00535 NP_661348.1 identified by match to PFAM protein family HMM PF01610 NP_661352.1 identified by match to PFAM protein family HMM PF00005 NP_661353.1 identified by match to PFAM protein family HMM PF00528 NP_661354.1 identified by match to PFAM protein family HMM PF01729 NP_661356.1 identified by match to PFAM protein family HMM PF00005 NP_661358.1 identified by match to PFAM protein family HMM PF00533 NP_661363.1 identified by match to PFAM protein family HMM PF01209 NP_661364.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers NP_661370.1 similar to GP:10802615; identified by sequence similarity NP_661373.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain NP_661376.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide NP_661377.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide NP_661379.1 identified by match to PFAM protein family HMM PF00849 NP_661384.1 identified by match to PFAM protein family HMM PF00361 NP_661394.1 similar to SP:P31077 GB:X65042 PID:48528; identified by sequence similarity NP_661395.1 identified by match to PFAM protein family HMM PF00037 NP_661396.1 identified by match to PFAM protein family HMM PF00384 NP_661398.1 identified by match to PFAM protein family HMM PF00909 NP_661399.1 identified by match to PFAM protein family HMM PF00543 NP_661402.1 identified by match to PFAM protein family HMM PF00776 NP_661409.1 identified by match to PFAM protein family HMM PF00575 NP_661411.1 identified by match to PFAM protein family HMM PF00875 NP_661412.1 identified by match to PFAM protein family HMM PF00117 NP_661418.1 identified by match to PFAM protein family HMM PF01610 NP_661421.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_661424.1 identified by match to PFAM protein family HMM PF00561 NP_661427.1 identified by match to PFAM protein family HMM PF00005 NP_661429.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring NP_661430.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth NP_661431.1 identified by match to PFAM protein family HMM PF00072 NP_661432.1 identified by match to TIGR protein family HMM TIGR00364 NP_661435.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis NP_661436.1 identified by match to PFAM protein family HMM PF00535 NP_661438.1 identified by match to PFAM protein family HMM PF01545 NP_661440.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP NP_661441.1 identified by match to PFAM protein family HMM PF00571 NP_661443.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate NP_661445.1 identified by match to PFAM protein family HMM PF02547 NP_661446.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer NP_661447.1 identified by match to TIGR protein family HMM TIGR00904 NP_661448.1 identified by match to PFAM protein family HMM PF00534 NP_661451.1 identified by match to PFAM protein family HMM PF02687 NP_661452.1 identified by match to PFAM protein family HMM PF00005 NP_661454.1 identified by match to PFAM protein family HMM PF02321 NP_661455.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_661458.1 identified by match to PFAM protein family HMM PF01551 NP_661460.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers NP_661461.1 identified by match to PFAM protein family HMM PF00890 NP_661462.1 PvlArgDC; converts arginine to agmatine and carbon dioxide; has a role in polyamine metabolism; in Methanococcus jannaschii this enzyme self-cleaves at serine-serine bond to form alpha (N-terminal) and beta (C-terminal) subunits; the alpha subunit contains a catalytically active pyruvoyl group; the beta subunit contains the substrate-binding residues; forms homotrimers of the alpha/beta complex NP_661463.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) NP_661464.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation NP_661465.1 identified by match to PFAM protein family HMM PF01565 NP_661466.1 identified by match to PFAM protein family HMM PF00905 NP_661468.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall NP_661469.1 identified by match to PFAM protein family HMM PF00166 NP_661470.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate NP_661476.1 identified by match to PFAM protein family HMM PF01073 NP_661478.1 Catalyzes the rate-limiting step in dNTP synthesis NP_661488.1 identified by match to PFAM protein family HMM PF00383 NP_661490.1 identified by match to PFAM protein family HMM PF00005 NP_661491.1 identified by match to TIGR protein family HMM TIGR00557 NP_661497.1 identified by match to PFAM protein family HMM PF00270 NP_661498.1 identified by match to PFAM protein family HMM PF00753 NP_661502.1 identified by match to PFAM protein family HMM PF00589 NP_661503.1 identified by match to PFAM protein family HMM PF01029 NP_661504.1 identified by match to PFAM protein family HMM PF01041 NP_661505.1 identified by match to PFAM protein family HMM PF00561 NP_661506.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_661509.1 identified by match to PFAM protein family HMM PF00106 NP_661510.1 identified by match to PFAM protein family HMM PF00313 NP_661511.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase NP_661512.1 catalyzes the formation of 2-isopropylmalate from 1-methyl-2-oxobutanoate and acetyl-CoA NP_661513.1 identified by match to PFAM protein family HMM PF00694 NP_661514.1 identified by match to PFAM protein family HMM PF00330 NP_661515.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis NP_661516.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis NP_661517.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit NP_661518.1 identified by match to PFAM protein family HMM PF00205 NP_661519.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis NP_661520.1 identified by match to Prosite PS00004; contains internal deletion NP_661521.1 identified by match to PFAM protein family HMM PF00467 NP_661524.1 identified by match to PFAM protein family HMM PF00293 NP_661528.1 identified by match to PFAM protein family HMM PF00122 NP_661529.1 identified by match to PFAM protein family HMM PF01879 NP_661530.1 identified by match to PFAM protein family HMM PF01618 NP_661531.1 identified by match to PFAM protein family HMM PF02472 NP_661533.1 similar to GB:M28232 SP:P19935 PID:148020 GB:U00096 PID:1651332; identified by sequence similarity NP_661535.1 identified by match to PFAM protein family HMM PF00691 NP_661538.1 similar to PID:624955; identified by sequence similarity NP_661540.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_661541.1 identified by match to PFAM protein family HMM PF00011 NP_661545.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response NP_661546.1 identified by match to PFAM protein family HMM PF01494 NP_661547.1 identified by match to PFAM protein family HMM PF01262 NP_661548.1 identified by match to PFAM protein family HMM PF00111 NP_661549.1 identified by match to PFAM protein family HMM PF00111 NP_661550.1 identified by match to PFAM protein family HMM PF00270 NP_661552.1 identified by match to PFAM protein family HMM PF00005 NP_661553.1 identified by match to PFAM protein family HMM PF00072 NP_661555.1 identified by match to PFAM protein family HMM PF00512 NP_661557.1 identified by match to PFAM protein family HMM PF00293 NP_661559.1 identified by match to PFAM protein family HMM PF00578 NP_661562.1 identified by match to PFAM protein family HMM PF00690 NP_661564.1 identified by match to PFAM protein family HMM PF00005 NP_661565.1 identified by match to PFAM protein family HMM PF00528 NP_661566.1 identified by match to PFAM protein family HMM PF01100 NP_661570.1 similar to GP:3482870; identified by sequence similarity NP_661571.1 identified by match to PFAM protein family HMM PF02384 NP_661575.1 identified by match to PFAM protein family HMM PF01420 NP_661580.1 similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743; identified by sequence similarity NP_661583.1 identified by match to PFAM protein family HMM PF00293 NP_661590.1 identified by match to PFAM protein family HMM PF01909 NP_661591.1 identified by match to PFAM protein family HMM PF00899 NP_661592.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center NP_661593.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate NP_661594.1 identified by match to PFAM protein family HMM PF02597 NP_661595.1 identified by match to PFAM protein family HMM PF00291 NP_661596.1 identified by match to PFAM protein family HMM PF01041 NP_661598.1 identified by match to PFAM protein family HMM PF01053 NP_661599.1 identified by match to PFAM protein family HMM PF01863 NP_661601.1 identified by match to PFAM protein family HMM PF01262 NP_661603.1 identified by match to PFAM protein family HMM PF03073 NP_661609.1 identified by match to PFAM protein family HMM PF00916 NP_661611.1 identified by match to PFAM protein family HMM PF00999 NP_661612.1 identified by match to PFAM protein family HMM PF00561 NP_661613.1 identified by match to PFAM protein family HMM PF00697 NP_661614.1 identified by match to PFAM protein family HMM PF00763 NP_661615.1 similar to PID:694120 SP:Q49135; identified by sequence similarity NP_661616.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine NP_661617.2 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase NP_661621.1 identified by match to PFAM protein family HMM PF01844 NP_661622.1 identified by match to PFAM protein family HMM PF00132 NP_661624.1 identified by match to PFAM protein family HMM PF00293 NP_661625.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily NP_661629.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP NP_661630.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis NP_661639.1 identified by match to PFAM protein family HMM PF01662 NP_661640.1 similar to GP:1808672; identified by sequence similarity NP_661641.1 identified by match to PFAM protein family HMM PF00383 NP_661642.1 identified by match to PFAM protein family HMM PF00383 NP_661648.1 identified by match to PFAM protein family HMM PF00005 NP_661649.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein NP_661650.1 identified by match to PFAM protein family HMM PF00128 NP_661651.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine NP_661652.1 identified by match to PFAM protein family HMM PF00004 NP_661653.1 identified by match to PFAM protein family HMM PF02321 NP_661655.1 identified by match to PFAM protein family HMM PF01230 NP_661659.1 identified by match to PFAM protein family HMM PF00515 NP_661661.1 identified by match to PFAM protein family HMM PF00507 NP_661662.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen NP_661663.1 identified by match to PFAM protein family HMM PF00329 NP_661664.1 identified by match to PFAM protein family HMM PF00346 NP_661665.1 identified by match to PFAM protein family HMM PF00146 NP_661666.1 identified by match to PFAM protein family HMM PF00037 NP_661667.1 identified by match to PFAM protein family HMM PF00499 NP_661668.1 identified by match to PFAM protein family HMM PF00420 NP_661669.1 identified by match to PFAM protein family HMM PF00361 NP_661670.1 identified by match to PFAM protein family HMM PF00361 NP_661671.1 identified by match to PFAM protein family HMM PF00361 NP_661672.1 identified by match to PFAM protein family HMM PF00374 NP_661675.1 identified by match to TIGR protein family HMM TIGR00072 NP_661676.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer NP_661677.1 identified by match to PFAM protein family HMM PF01242 NP_661680.1 identified by match to PFAM protein family HMM PF00085 NP_661687.1 similar to SP:P76134; identified by sequence similarity NP_661690.1 identified by match to PFAM protein family HMM PF01957 NP_661691.1 identified by match to PFAM protein family HMM PF01145 NP_661692.1 identified by match to PFAM protein family HMM PF00582 NP_661693.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins NP_661694.1 identified by match to PFAM protein family HMM PF02310 NP_661697.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin NP_661698.1 identified by match to PFAM protein family HMM PF02779 NP_661700.1 involved in a recombinational process of DNA repair, independent of the recBC complex NP_661701.1 identified by match to PFAM protein family HMM PF01593 NP_661709.1 identified by match to PFAM protein family HMM PF00122 NP_661712.1 identified by match to PFAM protein family HMM PF00009 NP_661716.1 identified by match to PFAM protein family HMM PF00324 NP_661717.1 identified by match to PFAM protein family HMM PF00719 NP_661719.1 identified by match to PFAM protein family HMM PF03102 NP_661723.1 molecular chaperone NP_661727.1 identified by match to TIGR protein family HMM TIGR00722 NP_661728.1 identified by match to PFAM protein family HMM PF00364 NP_661730.1 identified by match to PFAM protein family HMM PF00560 NP_661732.1 similar to GB:Pyro_h; identified by sequence similarity NP_661733.1 identified by match to PFAM protein family HMM PF00534 NP_661734.1 identified by match to PFAM protein family HMM PF01336 NP_661735.1 identified by match to PFAM protein family HMM PF00085 NP_661736.1 identified by match to PFAM protein family HMM PF00070 NP_661745.1 similar to GB:L05610 SP:P45573 PID:145087; identified by sequence similarity NP_661746.1 identified by match to PFAM protein family HMM PF01077 NP_661747.1 identified by match to PFAM protein family HMM PF00037 NP_661748.1 unknown function NP_661749.1 identified by match to PFAM protein family HMM PF02635 NP_661750.1 similar to GP:3228383; identified by sequence similarity NP_661751.1 similar to GP:3228384; identified by sequence similarity NP_661756.1 ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms NP_661758.1 identified by match to PFAM protein family HMM PF00037 NP_661759.1 catalyzes the reduction of adenosine 5'-phosphosulfate to AMP and sulfite NP_661760.1 identified by match to PFAM protein family HMM PF00037 NP_661761.1 identified by match to PFAM protein family HMM PF00037 NP_661771.1 contains internal deletion NP_661772.1 identified by match to PFAM protein family HMM PF00588 NP_661776.1 identified by match to PFAM protein family HMM PF00991 NP_661780.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate NP_661782.1 identified by match to PFAM protein family HMM PF00702 NP_661788.1 identified by match to PFAM protein family HMM PF01449 NP_661789.1 identified by match to PFAM protein family HMM PF01449 NP_661790.1 identified by match to PFAM protein family HMM PF00528 NP_661791.1 identified by match to PFAM protein family HMM PF00528 NP_661792.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation NP_661793.1 identified by match to PFAM protein family HMM PF01895 NP_661799.1 identified by match to PFAM protein family HMM PF00271 NP_661801.1 identified by match to PFAM protein family HMM PF01555 NP_661811.1 identified by match to PFAM protein family HMM PF00805 NP_661812.1 identified by match to PFAM protein family HMM PF00535 NP_661813.1 identified by match to PFAM protein family HMM PF00106 NP_661815.1 identified by match to PFAM protein family HMM PF00689 NP_661816.1 identified by match to PFAM protein family HMM PF00324 NP_661822.1 identified by match to TIGR protein family HMM TIGR00313 NP_661823.1 identified by match to PFAM protein family HMM PF01497 NP_661824.1 identified by match to PFAM protein family HMM PF00293 NP_661827.1 identified by match to PFAM protein family HMM PF02690 NP_661828.1 identified by match to PFAM protein family HMM PF00593 NP_661830.1 identified by match to PFAM protein family HMM PF00881 NP_661831.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation NP_661832.1 identified by match to PFAM protein family HMM PF00155 NP_661833.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group NP_661835.1 identified by match to PFAM protein family HMM PF01032 NP_661836.1 identified by match to PFAM protein family HMM PF00005 NP_661838.1 identified by match to PFAM protein family HMM PF02283 NP_661839.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole NP_661840.1 identified by match to PFAM protein family HMM PF00561 NP_661841.1 identified by match to PFAM protein family HMM PF02654 NP_661844.1 identified by match to PFAM protein family HMM PF00465 NP_661846.1 identified by match to PFAM protein family HMM PF00005 NP_661849.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient NP_661853.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase NP_661854.1 identified by match to PFAM protein family HMM PF00597 NP_661856.1 identified by match to PFAM protein family HMM PF00456 NP_661857.1 identified by match to TIGR protein family HMM TIGR00095 NP_661858.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA NP_661859.1 identified by match to PFAM protein family HMM PF00155 NP_661862.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content NP_661865.1 identified by match to PFAM protein family HMM PF01740 NP_661866.1 identified by match to PFAM protein family HMM PF01715 NP_661867.1 identified by match to PFAM protein family HMM PF02545 NP_661868.1 identified by match to PFAM protein family HMM PF00474 NP_661869.1 identified by match to PFAM protein family HMM PF00294 NP_661871.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability NP_661872.1 identified by match to PFAM protein family HMM PF01464 NP_661873.1 identified by match to PFAM protein family HMM PF02374 NP_661874.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive NP_661878.1 identified by match to PFAM protein family HMM PF00543 NP_661879.1 identified by match to PFAM protein family HMM PF00909 NP_661880.1 identified by match to PFAM protein family HMM PF02518 NP_661881.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family NP_661882.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide NP_661883.1 identified by match to PFAM protein family HMM PF01743 NP_661884.1 identified by match to PFAM protein family HMM PF01408 NP_661885.1 identified by match to PFAM protein family HMM PF00083 NP_661887.1 identified by match to PFAM protein family HMM PF00383 NP_661889.1 identified by match to PFAM protein family HMM PF00730 NP_661893.1 identified by match to PFAM protein family HMM PF00773 NP_661896.1 identified by match to TIGR protein family HMM TIGR00686 NP_661903.1 identified by match to PFAM protein family HMM PF01566 NP_661904.1 identified by match to PFAM protein family HMM PF00582 NP_661908.1 identified by match to PFAM protein family HMM PF00034 NP_661909.1 identified by match to TIGR protein family HMM TIGR01409 NP_661910.1 similar to GP:8517645; identified by sequence similarity NP_661911.1 similar to PID:2246425; identified by sequence similarity NP_661913.1 identified by match to PFAM protein family HMM PF01009 NP_661917.1 identified by match to PFAM protein family HMM PF00070 NP_661920.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 NP_661922.1 similar to GP:2605821; identified by sequence similarity NP_661923.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane NP_661924.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit NP_661925.1 identified by match to PFAM protein family HMM PF00270 NP_661927.1 identified by match to PFAM protein family HMM PF02608 NP_661929.1 identified by match to PFAM protein family HMM PF00027 NP_661930.1 identified by match to PFAM protein family HMM PF00929 NP_661933.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis NP_661934.1 identified by match to PFAM protein family HMM PF01557 NP_661936.1 identified by match to PFAM protein family HMM PF00805 NP_661937.1 similar to GP:3089168; identified by sequence similarity NP_661939.1 identified by match to PFAM protein family HMM PF01812 NP_661940.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate NP_661941.1 identified by match to PFAM protein family HMM PF02502 NP_661943.1 identified by match to PFAM protein family HMM PF01546 NP_661944.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate NP_661945.1 identified by match to PFAM protein family HMM PF00595 NP_661946.1 catalyzes the formation of arginine from (N-L-arginino)succinate NP_661949.1 identified by match to PFAM protein family HMM PF01546 NP_661951.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis NP_661959.1 identified by match to TIGR protein family HMM TIGR01450 NP_661960.1 identified by match to PFAM protein family HMM PF00580 NP_661961.1 identified by match to TIGR protein family HMM TIGR01447 NP_661963.1 identified by match to PFAM protein family HMM PF00578 NP_661965.1 identified by match to PFAM protein family HMM PF02424 NP_661966.1 identified by match to PFAM protein family HMM PF02683 NP_661969.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group NP_661976.1 catalyzes the formation of acetyl phosphate from acetyl-CoA and phosphate; can also act with other short-chain acyl-CoAs NP_661979.1 identified by match to PFAM protein family HMM PF00549 NP_661981.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein NP_661983.1 identified by match to PFAM protein family HMM PF00005 NP_661987.1 similar to GP:9951403; identified by sequence similarity NP_661990.1 identified by match to PFAM protein family HMM PF00583 NP_661991.1 identified by match to PFAM protein family HMM PF00301 NP_661992.1 identified by match to PFAM protein family HMM PF00301 NP_661996.1 identified by match to PFAM protein family HMM PF00990 NP_662000.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate NP_662001.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate NP_662002.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate NP_662003.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation NP_662004.1 identified by match to PFAM protein family HMM PF02863 NP_662005.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming NP_662026.1 identified by match to PFAM protein family HMM PF00271 NP_662030.1 identified by match to PFAM protein family HMM PF00037 NP_662034.1 identified by match to PFAM protein family HMM PF00106 NP_662035.1 identified by match to PFAM protein family HMM PF00999 NP_662036.1 identified by match to PFAM protein family HMM PF00877 NP_662039.1 identified by match to PFAM protein family HMM PF00149 NP_662041.1 identified by match to PFAM protein family HMM PF00037 NP_662042.1 identified by match to PFAM protein family HMM PF01041 NP_662043.1 identified by match to PFAM protein family HMM PF00465 NP_662044.1 identified by match to PFAM protein family HMM PF01128 NP_662047.1 identified by match to PFAM protein family HMM PF00501 NP_662050.1 similar to GP:2769574; identified by sequence similarity NP_662051.1 similar to GB:U00089 PID:1673692; identified by sequence similarity NP_662052.1 similar to GP:4467889; identified by sequence similarity NP_662053.1 identified by match to PFAM protein family HMM PF00730 NP_662054.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NP_662055.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA NP_662056.1 identified by match to PFAM protein family HMM PF01782 NP_662057.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity NP_662058.1 identified by match to PFAM protein family HMM PF00448 NP_662059.1 identified by match to PFAM protein family HMM PF00294 NP_662062.1 identified by match to PFAM protein family HMM PF00595 NP_662065.1 identified by match to PFAM protein family HMM PF02581 NP_662066.1 identified by match to PFAM protein family HMM PF02581 NP_662067.1 identified by match to PFAM protein family HMM PF00294 NP_662068.1 identified by match to PFAM protein family HMM PF00984 NP_662071.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides NP_662072.1 identified by match to PFAM protein family HMM PF01368 NP_662074.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance NP_662076.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP NP_662078.1 identified by match to PFAM protein family HMM PF00271 NP_662081.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis NP_662082.1 heat shock protein involved in degradation of misfolded proteins NP_662083.1 heat shock protein involved in degradation of misfolded proteins NP_662084.1 identified by match to PFAM protein family HMM PF00309 NP_662086.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents NP_662088.1 identified by match to PFAM protein family HMM PF00107 NP_662096.1 identified by match to PFAM protein family HMM PF00348 NP_662097.1 identified by match to PFAM protein family HMM PF00902 NP_662099.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis NP_662101.1 identified by match to PFAM protein family HMM PF00081 NP_662105.1 identified by match to PFAM protein family HMM PF00085 NP_662118.1 identified by match to PFAM protein family HMM PF01565 NP_662120.1 similar to PID:1477486; identified by sequence similarity; contains internal deletion NP_662121.1 identified by match to PFAM protein family HMM PF01360 NP_662124.1 similar to GP:9757183; identified by sequence similarity NP_662127.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins NP_662128.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_662129.1 identified by match to PFAM protein family HMM PF01256 NP_662130.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate NP_662131.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock NP_662133.1 identified by match to PFAM protein family HMM PF02754 NP_662134.1 identified by match to PFAM protein family HMM PF00037 NP_662135.1 identified by match to PFAM protein family HMM PF02662 NP_662138.1 identified by match to PFAM protein family HMM PF00175 NP_662140.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_662141.1 identified by match to PFAM protein family HMM PF00561 NP_662143.1 identified by match to PFAM protein family HMM PF00588 NP_662144.1 identified by match to PFAM protein family HMM PF00155 NP_662146.1 identified by match to PFAM protein family HMM PF01370 NP_662147.1 identified by match to PFAM protein family HMM PF02562 NP_662148.1 identified by match to PFAM protein family HMM PF00037 NP_662149.1 identified by match to PFAM protein family HMM PF00037 NP_662153.1 identified by match to PFAM protein family HMM PF00768 NP_662155.1 identified by match to PFAM protein family HMM PF01810 NP_662156.1 identified by match to PFAM protein family HMM PF00583 NP_662158.1 identified by match to PFAM protein family HMM PF01040 NP_662159.1 identified by match to PFAM protein family HMM PF00535 NP_662163.1 identified by match to PFAM protein family HMM PF00107 NP_662166.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae NP_662174.1 identified by match to PFAM protein family HMM PF02321 NP_662175.1 identified by match to PFAM protein family HMM PF00873 NP_662176.1 identified by match to PFAM protein family HMM PF00364 NP_662177.1 identified by match to PFAM protein family HMM PF01035 NP_662181.1 identified by match to PFAM protein family HMM PF00478 NP_662183.1 identified by match to PFAM protein family HMM PF02514 NP_662184.1 identified by match to PFAM protein family HMM PF00092 NP_662185.1 identified by match to PFAM protein family HMM PF01078 NP_662186.1 identified by match to PFAM protein family HMM PF00070 NP_662187.1 identified by match to PFAM protein family HMM PF00849 NP_662189.1 identified by match to PFAM protein family HMM PF00326 NP_662191.1 identified by match to PFAM protein family HMM PF00005 NP_662196.1 identified by match to PFAM protein family HMM PF00106 NP_662200.1 identified by match to PFAM protein family HMM PF00561 NP_662201.1 identified by match to PFAM protein family HMM PF02223 NP_662203.1 identified by match to PFAM protein family HMM PF00702 NP_662205.1 identified by match to PFAM protein family HMM PF01128 NP_662206.1 identified by match to PFAM protein family HMM PF02584 NP_662211.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes NP_662212.1 identified by match to PFAM protein family HMM PF00004 NP_662213.1 identified by match to TIGR protein family HMM TIGR00765 NP_662214.1 identified by match to PFAM protein family HMM PF02915 NP_662217.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis NP_662218.1 identified by match to PFAM protein family HMM PF00994 NP_662219.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; MobB is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway NP_662220.1 identified by match to PFAM protein family HMM PF01444 NP_662225.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_662227.1 identified by match to PFAM protein family HMM PF01066 NP_662228.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate NP_662229.1 identified by match to PFAM protein family HMM PF02539 NP_662232.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli NP_662234.1 identified by match to PFAM protein family HMM PF02321 NP_662235.1 identified by match to PFAM protein family HMM PF00529 NP_662236.1 identified by match to PFAM protein family HMM PF00005 NP_662237.1 identified by match to PFAM protein family HMM PF02687 NP_662238.1 identified by match to PFAM protein family HMM PF02687 NP_662240.1 identified by match to PFAM protein family HMM PF00691 NP_662245.1 identified by match to PFAM protein family HMM PF00072 NP_662247.1 identified by match to PFAM protein family HMM PF00132 NP_662248.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP NP_662249.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response NP_662251.1 identified by match to PFAM protein family HMM PF00528 NP_662252.1 identified by match to PFAM protein family HMM PF00293 NP_662254.1 identified by match to TIGR protein family HMM TIGR00360 NP_662255.1 identified by match to PFAM protein family HMM PF02219 NP_662258.1 identified by match to PFAM protein family HMM PF00278 NP_662260.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_662263.1 identified by match to PFAM protein family HMM PF00072 NP_662265.1 identified by match to PFAM protein family HMM PF00785 NP_662268.1 identified by match to PFAM protein family HMM PF00155 NP_662269.1 identified by match to PFAM protein family HMM PF00111 NP_662273.1 identified by match to PFAM protein family HMM PF00494 NP_662274.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 NP_662278.1 identified by match to PFAM protein family HMM PF00571 NP_662282.1 identified by match to PFAM protein family HMM PF00072 NP_662283.1 identified by match to PFAM protein family HMM PF01702 NP_662288.1 identified by match to TIGR protein family HMM TIGR01448 NP_662291.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis NP_662292.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis NP_662294.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP NP_662297.1 identified by match to PFAM protein family HMM PF00120 NP_662298.1 identified by match to PFAM protein family HMM PF01037 NP_662300.1 identified by match to PFAM protein family HMM PF01593 NP_662302.1 identified by match to PFAM protein family HMM PF00535 NP_662303.1 similar to GP:3089175; identified by sequence similarity NP_662304.1 identified by match to PFAM protein family HMM PF00692 NP_662306.1 identified by match to PFAM protein family HMM PF00496 NP_662307.1 similar to SP:P26165 PID:46110; identified by sequence similarity NP_662308.1 identified by match to PFAM protein family HMM PF00107 NP_662309.1 identified by match to PFAM protein family HMM PF00142 NP_662310.1 identified by match to PFAM protein family HMM PF00009 NP_662312.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins NP_662313.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis NP_662314.1 identified by match to PFAM protein family HMM PF02602 NP_662316.1 identified by match to PFAM protein family HMM PF00459 NP_662317.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate NP_662318.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis NP_662322.1 identified by match to PFAM protein family HMM PF00132 NP_662323.1 identified by match to PFAM protein family HMM PF01242 NP_662326.1 identified by match to PFAM protein family HMM PF01444 NP_662328.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine NP_662330.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate NP_662332.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus NP_662333.1 identified by match to PFAM protein family HMM PF00089 NP_662334.1 identified by match to PFAM protein family HMM PF00425 NP_662336.1 identified by match to PFAM protein family HMM PF00461 NP_662337.1 binds to the ribosome on the universally-conserved alpha-sarcin loop NP_662339.1 identified by match to PFAM protein family HMM PF00551 NP_662340.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_662341.1 identified by match to PFAM protein family HMM PF01475 NP_662342.1 identified by match to PFAM protein family HMM PF00893 NP_662343.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis NP_662347.1 similar to GP:161532; identified by sequence similarity NP_662357.1 identified by match to PFAM protein family HMM PF00230 NP_662358.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway NP_662359.1 identified by match to PFAM protein family HMM PF00005 NP_662360.1 identified by match to PFAM protein family HMM PF00083 NP_662362.1 identified by match to PFAM protein family HMM PF01041 NP_662364.1 identified by match to PFAM protein family HMM PF01225 NP_662365.1 identified by match to PFAM protein family HMM PF00044 NP_662369.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_662370.1 identified by match to PFAM protein family HMM PF01025 NP_662371.1 identified by match to PFAM protein family HMM PF01628 NP_662372.1 identified by match to PFAM protein family HMM PF01209 NP_662376.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_662377.1 identified by match to PFAM protein family HMM PF00578 NP_662378.1 identified by match to PFAM protein family HMM PF00860 NP_662379.1 identified by match to PFAM protein family HMM PF00795 NP_662380.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis NP_662382.1 identified by match to PFAM protein family HMM PF00158 NP_662383.1 identified by match to PFAM protein family HMM PF00795 NP_662384.1 identified by match to PFAM protein family HMM PF02327 NP_662386.1 identified by match to PFAM protein family HMM PF00005 NP_662388.1 This protein performs the mismatch recognition step during the DNA repair process NP_662390.1 identified by match to PFAM protein family HMM PF00829 NP_662391.1 involved in the peptidyltransferase reaction during translation NP_662392.1 Catalyzes the reversible oxidation of malate to oxaloacetate NP_662394.1 identified by match to PFAM protein family HMM PF01435 NP_662395.1 identified by match to PFAM protein family HMM PF00795 NP_662396.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate NP_662397.1 identified by match to PFAM protein family HMM PF00070 NP_662399.1 cyclase; catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase NP_662401.1 identified by match to PFAM protein family HMM PF02416 NP_662410.1 identified by match to PFAM protein family HMM PF00871 NP_662411.1 identified by match to PFAM protein family HMM PF00071 NP_662412.1 identified by match to PFAM protein family HMM PF00156 NP_662413.1 identified by match to PFAM protein family HMM PF00682 NP_662414.1 identified by match to PFAM protein family HMM PF00158 NP_662417.1 nitrogenase iron protein; nitrogenase component 2; with component 1, an molybdenum-iron protein, catalyzes the fixation of nitrogen to ammonia; nitrogen reductase provides electrons to the nitrogenase complex NP_662418.1 identified by match to PFAM protein family HMM PF00543 NP_662419.1 identified by match to PFAM protein family HMM PF00543 NP_662420.1 identified by match to PFAM protein family HMM PF00148 NP_662421.1 identified by match to PFAM protein family HMM PF00148 NP_662422.1 identified by match to PFAM protein family HMM PF00148 NP_662423.1 identified by match to PFAM protein family HMM PF00148 NP_662424.1 identified by match to PFAM protein family HMM PF01444 NP_662425.1 similar to SP:P07324 PID:40563; identified by sequence similarity NP_662426.1 identified by match to PFAM protein family HMM PF00593 NP_662427.1 identified by match to PFAM protein family HMM PF03459 NP_662429.1 identified by match to PFAM protein family HMM PF01842 NP_662430.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion NP_662432.1 identified by match to PFAM protein family HMM PF00675 NP_662435.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain NP_662436.1 identified by match to PFAM protein family HMM PF00574 NP_662437.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor NP_662438.1 identified by match to TIGR protein family HMM TIGR00515 NP_662440.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate NP_662442.1 identified by match to PFAM protein family HMM PF01578 NP_662448.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity NP_662450.1 identified by match to PFAM protein family HMM PF00781 NP_662451.1 identified by match to PFAM protein family HMM PF01451 NP_662456.1 identified by match to PFAM protein family HMM PF00171 NP_662458.1 catalyzes branch migration in Holliday junction intermediates NP_662459.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_662460.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs NP_662461.1 similar to SP:P09999 GB:M95287 GB:L06418 GB:X12868 GB:J02967; identified by sequence similarity NP_662463.1 similar to GB:Z30315 PID:535274; identified by sequence similarity NP_662469.1 identified by match to PFAM protein family HMM PF01618 NP_662471.1 identified by match to PFAM protein family HMM PF01751 NP_662473.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_662474.1 identified by match to PFAM protein family HMM PF00925 NP_662475.1 identified by match to PFAM protein family HMM PF00289 NP_662480.1 identified by match to PFAM protein family HMM PF01180 NP_662484.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate NP_662485.1 identified by match to PFAM protein family HMM PF02687 NP_662486.1 identified by match to PFAM protein family HMM PF00365 NP_662488.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids NP_662490.1 identified by match to PFAM protein family HMM PF03091 NP_662491.1 identified by match to PFAM protein family HMM PF00557 NP_662492.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate NP_662493.1 identified by match to PFAM protein family HMM PF01040 NP_662494.1 required for 70S ribosome assembly NP_662495.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids NP_662498.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine NP_662499.1 identified by match to PFAM protein family HMM PF02416 NP_662501.1 identified by match to TIGR protein family HMM TIGR00611 NP_662507.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis NP_662508.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein NP_662509.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor NP_662510.1 identified by match to PFAM protein family HMM PF00588 NP_662511.1 identified by match to PFAM protein family HMM PF00037 NP_662512.1 identified by match to PFAM protein family HMM PF00515 NP_662513.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration NP_662514.1 identified by match to PFAM protein family HMM PF00528 NP_662515.1 identified by match to PFAM protein family HMM PF00496 NP_662516.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system NP_662518.1 identified by match to PFAM protein family HMM PF00589 NP_662521.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis NP_662522.1 similar to PID:2190048; identified by sequence similarity NP_662523.1 identified by match to PFAM protein family HMM PF00311 NP_662524.1 identified by match to PFAM protein family HMM PF01078 NP_662527.1 identified by match to PFAM protein family HMM PF01343 NP_662528.1 identified by match to PFAM protein family HMM PF00005 NP_662529.1 identified by match to PFAM protein family HMM PF00590 NP_662530.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine NP_662532.1 identified by match to PFAM protein family HMM PF00013 NP_662533.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase NP_662535.2 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA NP_662538.1 similar to SP:P07324 PID:40563; identified by sequence similarity NP_662543.1 identified by match to PFAM protein family HMM PF03073 NP_662544.1 identified by match to PFAM protein family HMM PF00459 NP_662545.1 catalyzes the zinc dependent deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis and catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP in fatty acid biosynthesis NP_662546.1 identified by match to PFAM protein family HMM PF01066 NP_662547.1 identified by match to PFAM protein family HMM PF02075 NP_662549.1 identified by match to PFAM protein family HMM PF00800 NP_662550.1 identified by match to PFAM protein family HMM PF00476 NP_662553.1 identified by match to PFAM protein family HMM PF00834 NP_662554.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water NP_662555.1 identified by match to PFAM protein family HMM PF00289 NP_662557.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis NP_662559.1 identified by match to PFAM protein family HMM PF02606 NP_662560.1 identified by match to PFAM protein family HMM PF00857 NP_662563.1 identified by match to PFAM protein family HMM PF01965 NP_662565.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_662566.1 identified by match to PFAM protein family HMM PF00122 NP_662572.1 identified by match to PFAM protein family HMM PF00005 NP_662578.1 identified by match to PFAM protein family HMM PF00072 NP_662579.1 identified by match to PFAM protein family HMM PF00702 NP_662581.1 catalyzes the reduction of hydroxylamine to ammonia and water NP_662583.1 identified by match to PFAM protein family HMM PF00037 NP_662586.1 similar to GB:AE000513; identified by sequence similarity NP_662587.1 identified by match to Prosite PS00142 NP_662588.1 identified by match to PFAM protein family HMM PF00809 NP_662589.1 identified by match to PFAM protein family HMM PF02463 NP_662590.1 identified by match to PFAM protein family HMM PF00702 NP_662591.1 identified by match to PFAM protein family HMM PF01029 NP_662592.1 identified by match to PFAM protein family HMM PF00730 NP_662594.1 identified by match to PFAM protein family HMM PF00425 NP_662595.1 identified by match to PFAM protein family HMM PF01966 NP_662596.1 identified by match to PFAM protein family HMM PF01879 NP_662597.1 identified by match to PFAM protein family HMM PF01300 NP_662598.1 identified by match to PFAM protein family HMM PF02663 NP_662600.1 identified by match to PFAM protein family HMM PF00027 NP_662605.1 identified by match to PFAM protein family HMM PF01758 NP_662606.1 identified by match to PFAM protein family HMM PF01451 NP_662608.1 identified by match to TIGR protein family HMM TIGR00411 NP_662610.1 identified by match to PFAM protein family HMM PF01555 NP_662614.1 similar to GB:AE000657; identified by sequence similarity NP_662616.1 identified by match to PFAM protein family HMM PF00037 NP_662617.1 identified by match to PFAM protein family HMM PF01047 NP_662618.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group NP_662620.1 identified by match to PFAM protein family HMM PF00210 NP_662622.1 identified by match to PFAM protein family HMM PF02421 NP_662623.1 similar to SP:P33649 PID:414746 PID:606343 GB:U00096 PID:1789812; identified by sequence similarity NP_662627.2 alkyl hydroperoxidase; catalyze the reduction of hydrogen peroxide to water and the reduction of alkyl hydroperoxides to the corresponding alcohols NP_662628.1 identified by match to PFAM protein family HMM PF01209 NP_662629.1 identified by match to PFAM protein family HMM PF01444 NP_662634.1 identified by match to PFAM protein family HMM PF00005 NP_662637.1 identified by match to PFAM protein family HMM PF01497 NP_662638.1 identified by match to PFAM protein family HMM PF01209 NP_662639.1 identified by match to PFAM protein family HMM PF00005 NP_662640.1 identified by match to PFAM protein family HMM PF00950 NP_662641.1 identified by match to PFAM protein family HMM PF00593 NP_662642.1 identified by match to PFAM protein family HMM PF00590 NP_662644.1 identified by match to PFAM protein family HMM PF03459 NP_662645.1 identified by match to PFAM protein family HMM PF00106 NP_662650.1 identified by match to PFAM protein family HMM PF00106 NP_662651.1 identified by match to PFAM protein family HMM PF00016 NP_662653.1 identified by match to PFAM protein family HMM PF00106 NP_662655.1 similar to SP:P26165 PID:46110; identified by sequence similarity NP_662656.1 similar to PID:1001780 PID:1001797; identified by sequence similarity NP_662657.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities NP_662658.1 Catalyzes the phosphorylation of UMP to UDP NP_662659.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu NP_662660.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit NP_662661.1 forms a direct contact with the tRNA during translation NP_662662.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit NP_662663.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains NP_662664.1 identified by match to PFAM protein family HMM PF01883 NP_662665.1 identified by match to PFAM protein family HMM PF01106 NP_662666.1 identified by match to PFAM protein family HMM PF01580 NP_662667.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein NP_662671.1 identified by match to PFAM protein family HMM PF00586 NP_662673.1 identified by match to PFAM protein family HMM PF01924 NP_662674.1 identified by match to TIGR protein family HMM TIGR00074 NP_662676.1 identified by match to PFAM protein family HMM PF00708 NP_662677.1 identified by match to PFAM protein family HMM PF01495 NP_662678.1 identified by match to PFAM protein family HMM PF01155 NP_662679.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis NP_662681.1 identified by match to PFAM protein family HMM PF00293 NP_662685.1 identified by match to PFAM protein family HMM PF00474 NP_662686.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NP_662687.1 identified by match to PFAM protein family HMM PF00515 NP_662688.1 identified by match to PFAM protein family HMM PF01488 NP_662689.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis NP_662690.1 identified by match to PFAM protein family HMM PF01026 NP_662692.1 identified by match to PFAM protein family HMM PF00160 NP_662694.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation NP_662695.1 identified by match to PFAM protein family HMM PF01008 NP_662697.1 identified by match to PFAM protein family HMM PF01654 NP_662698.1 identified by match to PFAM protein family HMM PF02322 NP_662700.1 identified by match to PFAM protein family HMM PF00005 NP_662701.1 identified by match to PFAM protein family HMM PF00005 NP_662702.1 similar to GB:U14003 SP:P39281 GB:U21726 PID:536993 PID:717134; identified by sequence similarity NP_662703.1 identified by match to PFAM protein family HMM PF01545 NP_662704.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine NP_662705.1 identified by match to PFAM protein family HMM PF00148 NP_662707.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides NP_662709.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS NP_662710.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine NP_662712.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain NP_662713.1 identified by match to PFAM protein family HMM PF00285 NP_662714.1 identified by match to PFAM protein family HMM PF00403 NP_662716.1 identified by match to PFAM protein family HMM PF00515 NP_662717.1 identified by match to PFAM protein family HMM PF00425 NP_662718.1 identified by match to PFAM protein family HMM PF02776 NP_662720.1 identified by match to PFAM protein family HMM PF00583 NP_662723.1 identified by match to PFAM protein family HMM PF00561 NP_662724.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA NP_662725.1 identified by match to PFAM protein family HMM PF01188 NP_662726.1 identified by match to PFAM protein family HMM PF00501 NP_662728.1 identified by match to PFAM protein family HMM PF01113 NP_662729.1 identified by match to PFAM protein family HMM PF02195 NP_662730.1 identified by match to PFAM protein family HMM PF00991 NP_662731.1 identified by match to PFAM protein family HMM PF02245 NP_662732.1 identified by match to PFAM protein family HMM PF00571 NP_662733.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs NP_662734.1 identified by match to PFAM protein family HMM PF02230 NP_662735.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity NP_662747.1 identified by match to PFAM protein family HMM PF00456 NP_662748.1 identified by match to PFAM protein family HMM PF01182 NP_662750.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate NP_662751.2 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate NP_662755.1 identified by match to TIGR protein family HMM TIGR00348 NP_662757.1 identified by match to PFAM protein family HMM PF01420 NP_662758.1 identified by match to PFAM protein family HMM PF02384 NP_662759.1 identified by match to PFAM protein family HMM PF00534 NP_662763.1 identified by match to PFAM protein family HMM PF00171 NP_662765.1 identified by match to PFAM protein family HMM PF00588 NP_662767.1 identified by match to PFAM protein family HMM PF01136 NP_662768.1 similar to PID:563905; identified by sequence similarity NP_662769.1 identified by match to PFAM protein family HMM PF00175 NP_662770.1 identified by match to PFAM protein family HMM PF01058 NP_662771.1 identified by match to PFAM protein family HMM PF00374 NP_662773.1 identified by match to PFAM protein family HMM PF00254 NP_662775.1 identified by match to PFAM protein family HMM PF01593 NP_662776.1 identified by match to PFAM protein family HMM PF00132 NP_662778.1 identified by match to PFAM protein family HMM PF00005 NP_662780.1 similar to GB:D10716 SP:P42349 PID:217099 PID:1653260; identified by sequence similarity NP_662785.1 identified by match to PFAM protein family HMM PF00561 NP_662790.1 similar to SP:P29568; identified by sequence similarity NP_662795.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis NP_662796.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA NP_662798.1 identified by match to PFAM protein family HMM PF00291 NP_662799.1 identified by match to PFAM protein family HMM PF00842 NP_662802.1 identified by match to PFAM protein family HMM PF01610 NP_662805.1 identified by match to PFAM protein family HMM PF01118 NP_662806.1 identified by match to PFAM protein family HMM PF01207 NP_662807.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs NP_662809.1 identified by match to PFAM protein family HMM PF00675 NP_662811.1 identified by match to TIGR protein family HMM TIGR00115 NP_662812.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids NP_662813.1 identified by match to PFAM protein family HMM PF01729 NP_662814.1 identified by match to PFAM protein family HMM PF02152 NP_662815.1 identified by match to PFAM protein family HMM PF01288 NP_662816.1 identified by match to PFAM protein family HMM PF02374 NP_662819.1 identified by match to PFAM protein family HMM PF02043 NP_662820.1 similar to GB:U09866 PID:497321; identified by sequence similarity NP_662822.1 identified by match to PFAM protein family HMM PF02374 NP_662823.1 identified by match to PFAM protein family HMM PF00970 NP_662824.1 identified by match to PFAM protein family HMM PF00436 NP_662828.1 identified by match to PFAM protein family HMM PF00155 NP_662830.1 identified by match to PFAM protein family HMM PF00593 NP_662832.1 identified by match to PFAM protein family HMM PF02514 NP_662834.1 catalyzes the formation of Mg-protoporphyrin IX from protoporphyrin IX and Mg(2+); first committed step of chlorophyll biosynthesis NP_662835.1 catalyzes the formation of Mg-protoporphyrin IX methyl ester and S-adenosyl-L-homocysteine from Mg-protoporphyrin IX and S-adenosyl-L-methionine NP_662838.1 identified by match to PFAM protein family HMM PF00070 NP_662839.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_662840.1 identified by match to PFAM protein family HMM PF01545 NP_662845.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge NP_662846.1 identified by match to PFAM protein family HMM PF00011 NP_662858.1 identified by match to PFAM protein family HMM PF01551 NP_662859.1 identified by match to PFAM protein family HMM PF00472 NP_662862.1 identified by match to PFAM protein family HMM PF00400 NP_662863.1 identified by match to PFAM protein family HMM PF00535 NP_662864.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors NP_662868.1 catalyzes the synthesis of bacteriochlorophyll c which is the primary pigment in the chlorosomes of the photosynthetic green bacteria NP_662869.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) NP_662870.1 identified by match to PFAM protein family HMM PF01592 NP_662871.1 identified by match to PFAM protein family HMM PF00266 NP_662876.1 identified by match to PFAM protein family HMM PF00571 NP_662877.1 identified by match to PFAM protein family HMM PF00578 NP_662878.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate NP_662881.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase NP_662883.1 identified by match to PFAM protein family HMM PF00480 NP_662884.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis NP_662886.1 identified by match to PFAM protein family HMM PF02473 NP_662888.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose NP_662890.1 similar to GP:3820550; identified by sequence similarity NP_662893.1 identified by match to PFAM protein family HMM PF00535 NP_662894.1 identified by match to PFAM protein family HMM PF00037 NP_662895.1 similar to PID:953218; identified by sequence similarity NP_662896.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate NP_662898.1 identified by match to PFAM protein family HMM PF00208 NP_662899.1 identified by match to PFAM protein family HMM PF00301 NP_662900.1 identified by match to PFAM protein family HMM PF00912 NP_662901.1 identified by match to PFAM protein family HMM PF00034 NP_662903.1 identified by match to PFAM protein family HMM PF01119 NP_662904.1 identified by match to PFAM protein family HMM PF00994 NP_662905.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways NP_662907.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit NP_662908.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit NP_662909.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate NP_662910.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine NP_662911.1 identified by match to PFAM protein family HMM PF01553 NP_662912.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not NP_662913.1 identified by match to PFAM protein family HMM PF01380 NP_662914.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III NP_662915.1 identified by match to PFAM protein family HMM PF02754 NP_662916.1 identified by match to PFAM protein family HMM PF00111 NP_662917.1 identified by match to PFAM protein family HMM PF00890 NP_662919.1 identified by match to PFAM protein family HMM PF00571 NP_662920.1 identified by match to PFAM protein family HMM PF00753 NP_662922.1 identified by match to PFAM protein family HMM PF00873 NP_662924.1 identified by match to PFAM protein family HMM PF02321 NP_662929.1 similar to PID:1377877; identified by sequence similarity NP_662931.1 identified by match to PFAM protein family HMM PF00483 NP_662933.1 identified by match to PFAM protein family HMM PF00474 NP_662934.1 identified by match to PFAM protein family HMM PF00072 NP_662935.1 identified by match to PFAM protein family HMM PF00072 NP_662936.1 identified by match to PFAM protein family HMM PF00072 NP_662937.1 identified by match to PFAM protein family HMM PF02043 NP_662939.1 similar to PID:1381651; identified by sequence similarity NP_662942.1 identified by match to PFAM protein family HMM PF00805 NP_662945.1 identified by match to PFAM protein family HMM PF02374 NP_662948.1 identified by match to PFAM protein family HMM PF02705 NP_662950.1 identified by match to PFAM protein family HMM PF00515 NP_662952.1 identified by match to PFAM protein family HMM PF03330 NP_662953.1 identified by match to PFAM protein family HMM PF00070 NP_662955.1 identified by match to PFAM protein family HMM PF00034 NP_662956.1 identified by match to TIGR protein family HMM TIGR01409 NP_662959.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE NP_662960.1 identified by match to PFAM protein family HMM PF00106 NP_662961.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era NP_662962.1 identified by match to PFAM protein family HMM PF02230 NP_662963.1 identified by match to PFAM protein family HMM PF00128 NP_662964.1 identified by match to PFAM protein family HMM PF00128 NP_662969.1 identified by match to PFAM protein family HMM PF02350 NP_662973.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway NP_662976.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling NP_662978.1 identified by match to PFAM protein family HMM PF00950 NP_662979.1 identified by match to PFAM protein family HMM PF00005 NP_662980.1 identified by match to PFAM protein family HMM PF01297 NP_662981.1 identified by match to PFAM protein family HMM PF00682 NP_662986.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_662987.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY NP_662988.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs NP_662989.1 identified by match to PFAM protein family HMM PF00698 NP_662990.1 identified by match to PFAM protein family HMM PF00106 NP_662991.1 carries the fatty acid chain in fatty acid biosynthesis NP_662992.1 identified by match to PFAM protein family HMM PF00109 NP_662993.1 identified by match to PFAM protein family HMM PF00035 NP_662995.1 similar to SP:P54458 PID:1303794 GB:AL009126; identified by sequence similarity NP_662996.1 similar to GB:M26404 SP:P14633 GB:X16025 GB:X55817 PID:145838; identified by sequence similarity NP_662997.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein NP_662998.1 identified by match to PFAM protein family HMM PF00933 NP_662999.1 identified by match to PFAM protein family HMM PF00148 NP_663000.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) NP_663001.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits NP_663002.1 identified by match to PFAM protein family HMM PF01632 NP_663003.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit NP_663004.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily NP_663006.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk NP_663007.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_663008.1 identified by match to PFAM protein family HMM PF00436 NP_663009.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 NP_663010.1 identified by match to PFAM protein family HMM PF01260 NP_663011.1 identified by match to PFAM protein family HMM PF01075 NP_663015.1 identified by match to PFAM protein family HMM PF00766 NP_663016.1 identified by match to PFAM protein family HMM PF01012 NP_663019.1 identified by match to PFAM protein family HMM PF00557 NP_663020.1 identified by match to PFAM protein family HMM PF00037 NP_663024.1 light-independent; with chlN(bchN) and chlB(bchB) reduces ring D of protochlorophyllide to form chlorophyllide a in chlorophyll/bacteriochlorophyll production NP_663025.1 light-independent reduction of protochlorophyllide to form chlorophyllide a NP_663026.1 light-independent reduction of protochlorophyllide to form chlorophyllide a NP_663028.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis NP_663029.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential NP_663030.1 identified by match to PFAM protein family HMM PF01610 NP_663032.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_663033.1 identified by match to PFAM protein family HMM PF00483 NP_663034.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA NP_663035.1 is a component of the macrolide binding site in the peptidyl transferase center NP_663036.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_663037.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination NP_663038.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 NP_663039.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA NP_663040.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif NP_663041.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 NP_663042.1 identified by match to PFAM protein family HMM PF00557 NP_663043.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_663044.1 late assembly protein NP_663045.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 NP_663046.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance NP_663047.1 binds 5S rRNA along with protein L5 and L25 NP_663048.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance NP_663049.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NP_663050.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif NP_663051.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 NP_663052.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel NP_663053.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase NP_663054.1 primary binding protein; helps mediate assembly; involved in translation fidelity NP_663055.1 one of the stabilizing components for the large ribosomal subunit NP_663056.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e NP_663057.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation NP_663058.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center NP_663059.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA NP_663060.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation NP_663061.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel NP_663062.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA NP_663063.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin NP_663064.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex NP_663065.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_663066.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_663067.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit NP_663068.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance NP_663070.1 identified by match to PFAM protein family HMM PF01648 NP_663076.1 identified by match to PFAM protein family HMM PF01544 NP_663080.1 identified by match to PFAM protein family HMM PF01554 NP_663081.1 identified by match to PFAM protein family HMM PF00534 NP_663083.1 identified by match to PFAM protein family HMM PF00535 NP_663084.1 identified by match to PFAM protein family HMM PF00534 NP_663085.1 identified by match to PFAM protein family HMM PF00381 NP_663086.1 catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate NP_663087.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication NP_663088.1 identified by match to PFAM protein family HMM PF02609 NP_663089.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_663093.1 identified by match to PFAM protein family HMM PF01661 NP_663096.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway NP_663098.1 identified by match to PFAM protein family HMM PF01817 NP_663106.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP NP_663108.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit NP_663109.1 identified by match to PFAM protein family HMM PF02823 NP_663110.1 identified by match to PFAM protein family HMM PF02016 NP_663112.1 identified by match to PFAM protein family HMM PF00590 NP_663113.1 identified by match to TIGR protein family HMM TIGR01470 NP_663114.1 similar to SP:P31077 GB:X65042 PID:48528; identified by sequence similarity NP_663115.1 identified by match to PFAM protein family HMM PF00037 NP_663116.1 similar to GB:AE000782; identified by sequence similarity NP_663117.1 identified by match to PFAM protein family HMM PF00037 NP_663118.1 identified by match to PFAM protein family HMM PF02665 NP_663121.1 unknown function NP_663122.1 identified by match to PFAM protein family HMM PF01077 NP_663123.1 similar to GB:L05610 SP:P45573 PID:145087; identified by sequence similarity NP_663124.1 identified by match to PFAM protein family HMM PF01656 NP_663128.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_663129.1 identified by match to PFAM protein family HMM PF01360 NP_663131.1 identified by match to PFAM protein family HMM PF00595 NP_663132.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway NP_663133.1 identified by match to PFAM protein family HMM PF00575 NP_663134.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids NP_663136.1 identified by match to PFAM protein family HMM PF00204 NP_663137.1 identified by match to PFAM protein family HMM PF00639 NP_663138.1 catalyzes the reversible formation of fumarate and ubiquinol from succinate and ubiquinone NP_663139.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol NP_663140.1 similar to GP:6580638; identified by sequence similarity NP_663145.1 identified by match to PFAM protein family HMM PF03330 NP_663152.1 identified by match to PFAM protein family HMM PF00004 NP_663154.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs NP_663155.1 identified by match to PFAM protein family HMM PF00136 NP_663156.1 identified by match to PFAM protein family HMM PF00258 NP_663158.1 identified by match to PFAM protein family HMM PF00470