-- dump date   	20140619_032454
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
707184000001	Uncharacterized conserved protein [Function unknown]; Region: COG2155
707184000002	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit [Translation, ribosomal structure and biogenesis]; Region: GatC; COG0721
707184000003	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
707184000004	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
707184000005	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) [Translation, ribosomal structure and biogenesis]; Region: GatB; COG0064
707184000006	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
707184000007	GatB domain; Region: GatB_Yqey; pfam02637
707184000008	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
707184000009	ribonuclease HIII; Region: rnhC; TIGR00716
707184000010	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
707184000011	RNA/DNA hybrid binding site [nucleotide binding]; other site
707184000012	active site
707184000013	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
707184000014	Helix-turn-helix domain; Region: HTH_25; pfam13413
707184000015	lipid A biosynthesis lauroyl acyltransferase; Provisional; Region: PRK05906
707184000016	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
707184000017	putative acyl-acceptor binding pocket; other site
707184000018	Uncharacterized conserved protein [Function unknown]; Region: COG1624
707184000019	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
707184000020	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
707184000021	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
707184000022	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
707184000023	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
707184000024	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
707184000025	putative active site [active]
707184000026	PhoH-like protein; Region: PhoH; pfam02562
707184000027	Bacterial SH3 domain homologues; Region: SH3b; smart00287
707184000028	Bacterial SH3 domain homologues; Region: SH3b; smart00287
707184000029	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
707184000030	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
707184000031	HIGH motif; other site
707184000032	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
707184000033	active site
707184000034	KMSKS motif; other site
707184000035	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
707184000036	tRNA binding surface [nucleotide binding]; other site
707184000037	anticodon binding site; other site
707184000038	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
707184000039	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
707184000040	Catalytic site [active]
707184000041	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
707184000042	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
707184000043	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
707184000044	peptide chain release factor 1; Validated; Region: prfA; PRK00591
707184000045	PCRF domain; Region: PCRF; pfam03462
707184000046	RF-1 domain; Region: RF-1; pfam00472
707184000047	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
707184000048	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707184000049	S-adenosylmethionine binding site [chemical binding]; other site
707184000050	signal recognition particle protein; Provisional; Region: PRK10867
707184000051	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
707184000052	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
707184000053	P loop; other site
707184000054	GTP binding site [chemical binding]; other site
707184000055	Signal peptide binding domain; Region: SRP_SPB; pfam02978
707184000056	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14522
707184000057	tRNA (guanine-N(1)-)-methyltransferase/unknown domain fusion protein; Reviewed; Region: trmD; PRK01037
707184000058	tRNA-(guanine-N1)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmD; COG0336
707184000059	ribosomal protein L19, bacterial type; Region: rplS_bact; TIGR01024
707184000060	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
707184000061	RNA/DNA hybrid binding site [nucleotide binding]; other site
707184000062	active site
707184000063	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
707184000064	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
707184000065	catalytic site [active]
707184000066	G-X2-G-X-G-K; other site
707184000067	methionyl-tRNA synthetase; Reviewed; Region: PRK12268
707184000068	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
707184000069	active site
707184000070	HIGH motif; other site
707184000071	KMSKS motif; other site
707184000072	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
707184000073	tRNA binding surface [nucleotide binding]; other site
707184000074	anticodon binding site; other site
707184000075	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
707184000076	AAA domain; Region: AAA_30; pfam13604
707184000077	Family description; Region: UvrD_C_2; pfam13538
707184000078	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
707184000079	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
707184000080	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Saccharomyces cerevisiae biotin-apoprotein ligase (ScBLP); Region: GATase1_ScBLP_like; cd03144
707184000081	conserved cys residue [active]
707184000082	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
707184000083	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
707184000084	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
707184000085	trimer interface [polypeptide binding]; other site
707184000086	active site
707184000087	Holliday junction resolvasome, helicase subunit [DNA replication, recombination, and repair]; Region: RuvB; COG2255
707184000088	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184000089	Walker A motif; other site
707184000090	ATP binding site [chemical binding]; other site
707184000091	Walker B motif; other site
707184000092	arginine finger; other site
707184000093	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
707184000094	Type II secretory pathway, pullulanase PulA and related glycosidases [Carbohydrate transport and metabolism]; Region: PulA; COG1523
707184000095	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
707184000096	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
707184000097	active site
707184000098	catalytic site [active]
707184000099	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
707184000100	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
707184000101	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
707184000102	dimer interface [polypeptide binding]; other site
707184000103	ssDNA binding site [nucleotide binding]; other site
707184000104	tetramer (dimer of dimers) interface [polypeptide binding]; other site
707184000105	multifunctional aminopeptidase A; Provisional; Region: PRK00913
707184000106	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
707184000107	interface (dimer of trimers) [polypeptide binding]; other site
707184000108	Substrate-binding/catalytic site; other site
707184000109	Zn-binding sites [ion binding]; other site
707184000110	hypothetical protein; Provisional; Region: PRK05907
707184000111	Predicted methyltransferases [General function prediction only]; Region: COG0313
707184000112	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
707184000113	putative SAM binding site [chemical binding]; other site
707184000114	homodimer interface [polypeptide binding]; other site
707184000115	coproporphyrinogen III oxidase; Provisional; Region: PRK06294
707184000116	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
707184000117	FeS/SAM binding site; other site
707184000118	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes [Energy production and conversion]; Region: SucA; COG0567
707184000119	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
707184000120	TPP-binding site [chemical binding]; other site
707184000121	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
707184000122	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
707184000123	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
707184000124	E3 interaction surface; other site
707184000125	lipoyl attachment site [posttranslational modification]; other site
707184000126	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
707184000127	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
707184000128	uncharacterized protein, YfiH family; Region: TIGR00726
707184000129	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
707184000130	1-hydroxy-2-methyl-2-(e)-butenyl 4-diphosphate synthase [Lipid metabolism]; Region: gcpE; COG0821
707184000131	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cd02749
707184000132	ADP-ribose binding site [chemical binding]; other site
707184000133	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
707184000134	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
707184000135	catalytic loop [active]
707184000136	iron binding site [ion binding]; other site
707184000137	type III secretion system protein; Validated; Region: PRK05910
707184000138	FHIPEP family; Region: FHIPEP; pfam00771
707184000139	RNA polymerase sigma factor sigma-28; Reviewed; Region: PRK05911
707184000140	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
707184000141	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
707184000142	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
707184000143	DNA binding residues [nucleotide binding]
707184000144	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
707184000145	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
707184000146	active site
707184000147	HIGH motif; other site
707184000148	dimer interface [polypeptide binding]; other site
707184000149	KMSKS motif; other site
707184000150	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707184000151	RNA binding surface [nucleotide binding]; other site
707184000152	6-phosphogluconate dehydrogenase (decarboxylating); Region: gnd; TIGR00873
707184000153	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
707184000154	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
707184000155	GTP-binding protein LepA; Provisional; Region: PRK05433
707184000156	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
707184000157	G1 box; other site
707184000158	putative GEF interaction site [polypeptide binding]; other site
707184000159	GTP/Mg2+ binding site [chemical binding]; other site
707184000160	Switch I region; other site
707184000161	G2 box; other site
707184000162	G3 box; other site
707184000163	Switch II region; other site
707184000164	G4 box; other site
707184000165	G5 box; other site
707184000166	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
707184000167	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
707184000168	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
707184000169	ADP/ATP carrier protein family; Region: AAA; TIGR00769
707184000170	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
707184000171	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
707184000172	intersubunit interface [polypeptide binding]; other site
707184000173	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
707184000174	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
707184000175	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
707184000176	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
707184000177	ABC-ATPase subunit  interface; other site
707184000178	dimer interface [polypeptide binding]; other site
707184000179	putative PBP binding regions; other site
707184000180	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
707184000181	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
707184000182	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
707184000183	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
707184000184	ABC-ATPase subunit  interface; other site
707184000185	dimer interface [polypeptide binding]; other site
707184000186	putative PBP binding regions; other site
707184000187	1-deoxy-D-xylulose 5-phosphate reductoisomerase [Lipid metabolism]; Region: Dxr; COG0743
707184000188	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
707184000189	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
707184000190	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
707184000191	RIP metalloprotease RseP; Region: TIGR00054
707184000192	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
707184000193	active site
707184000194	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
707184000195	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
707184000196	putative substrate binding region [chemical binding]; other site
707184000197	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
707184000198	Putative serine esterase (DUF676); Region: DUF676; pfam05057
707184000199	recF protein; Region: recf; TIGR00611
707184000200	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707184000201	Walker A/P-loop; other site
707184000202	ATP binding site [chemical binding]; other site
707184000203	Q-loop/lid; other site
707184000204	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707184000205	ABC transporter signature motif; other site
707184000206	Walker B; other site
707184000207	DNA polymerase III subunit beta; Validated; Region: PRK05643
707184000208	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
707184000209	putative DNA binding surface [nucleotide binding]; other site
707184000210	dimer interface [polypeptide binding]; other site
707184000211	beta-clamp/clamp loader binding surface; other site
707184000212	beta-clamp/translesion DNA polymerase binding surface; other site
707184000213	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
707184000214	SmpB-tmRNA interface; other site
707184000215	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
707184000216	ApbE family; Region: ApbE; pfam02424
707184000217	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14181
707184000218	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
707184000219	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
707184000220	homodimer interface [polypeptide binding]; other site
707184000221	NADP binding site [chemical binding]; other site
707184000222	substrate binding site [chemical binding]; other site
707184000223	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707184000224	PLD-like domain; Region: PLDc_2; pfam13091
707184000225	putative active site [active]
707184000226	catalytic site [active]
707184000227	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
707184000228	PLD-like domain; Region: PLDc_2; pfam13091
707184000229	putative active site [active]
707184000230	catalytic site [active]
707184000231	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
707184000232	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
707184000233	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
707184000234	4-alpha-glucanotransferase; Region: Glyco_hydro_77; pfam02446
707184000235	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
707184000236	HrpJ-like domain; Region: HrpJ; pfam07201
707184000237	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
707184000238	FHIPEP family; Region: FHIPEP; pfam00771
707184000239	type III secretion system protein; Validated; Region: PRK06298
707184000240	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
707184000241	GTP-binding protein YchF; Reviewed; Region: PRK09601
707184000242	YchF GTPase; Region: YchF; cd01900
707184000243	G1 box; other site
707184000244	GTP/Mg2+ binding site [chemical binding]; other site
707184000245	Switch I region; other site
707184000246	G2 box; other site
707184000247	Switch II region; other site
707184000248	G3 box; other site
707184000249	G4 box; other site
707184000250	G5 box; other site
707184000251	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
707184000252	FAD synthase [Coenzyme metabolism]; Region: RibF; COG0196
707184000253	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
707184000254	active site
707184000255	Riboflavin kinase; Region: Flavokinase; smart00904
707184000256	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00989
707184000257	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
707184000258	RNA binding site [nucleotide binding]; other site
707184000259	active site
707184000260	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
707184000261	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
707184000262	Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; Region: InfB; COG0532
707184000263	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
707184000264	G1 box; other site
707184000265	putative GEF interaction site [polypeptide binding]; other site
707184000266	GTP/Mg2+ binding site [chemical binding]; other site
707184000267	Switch I region; other site
707184000268	G2 box; other site
707184000269	G3 box; other site
707184000270	Switch II region; other site
707184000271	G4 box; other site
707184000272	G5 box; other site
707184000273	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
707184000274	Translation-initiation factor 2; Region: IF-2; pfam11987
707184000275	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
707184000276	transcription termination factor NusA; Region: NusA; TIGR01953
707184000277	NusA N-terminal domain; Region: NusA_N; pfam08529
707184000278	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
707184000279	RNA binding site [nucleotide binding]; other site
707184000280	homodimer interface [polypeptide binding]; other site
707184000281	NusA-like KH domain; Region: KH_5; pfam13184
707184000282	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
707184000283	G-X-X-G motif; other site
707184000284	ribosomal protein S1; Region: rpsA; TIGR00717
707184000285	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
707184000286	RNA binding site [nucleotide binding]; other site
707184000287	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
707184000288	RNA binding site [nucleotide binding]; other site
707184000289	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
707184000290	RNA binding site [nucleotide binding]; other site
707184000291	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
707184000292	RNA binding site [nucleotide binding]; other site
707184000293	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
707184000294	RNA binding site [nucleotide binding]; other site
707184000295	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
707184000296	RNA binding site [nucleotide binding]; other site
707184000297	domain interface; other site
707184000298	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
707184000299	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
707184000300	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
707184000301	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
707184000302	Flagellar biogenesis protein [Cell motility and secretion]; Region: FliO; COG3190
707184000303	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
707184000304	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
707184000305	active site
707184000306	motif I; other site
707184000307	motif II; other site
707184000308	enoyl-[acyl-carrier-protein] reductase; Region: PLN02730
707184000309	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
707184000310	NAD binding site [chemical binding]; other site
707184000311	homotetramer interface [polypeptide binding]; other site
707184000312	homodimer interface [polypeptide binding]; other site
707184000313	substrate binding site [chemical binding]; other site
707184000314	active site
707184000315	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
707184000316	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707184000317	RNA binding surface [nucleotide binding]; other site
707184000318	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
707184000319	active site
707184000320	A/G-specific adenine glycosylase; Region: mutY; TIGR01084
707184000321	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
707184000322	minor groove reading motif; other site
707184000323	helix-hairpin-helix signature motif; other site
707184000324	substrate binding pocket [chemical binding]; other site
707184000325	active site
707184000326	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
707184000327	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
707184000328	DNA binding and oxoG recognition site [nucleotide binding]
707184000329	Uncharacterized conserved protein [Function unknown]; Region: COG0327
707184000330	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
707184000331	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
707184000332	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
707184000333	ring oligomerisation interface [polypeptide binding]; other site
707184000334	ATP/Mg binding site [chemical binding]; other site
707184000335	stacking interactions; other site
707184000336	hinge regions; other site
707184000337	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
707184000338	oligomerisation interface [polypeptide binding]; other site
707184000339	mobile loop; other site
707184000340	roof hairpin; other site
707184000341	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
707184000342	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
707184000343	active site
707184000344	Zn binding site [ion binding]; other site
707184000345	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
707184000346	Clp amino terminal domain; Region: Clp_N; pfam02861
707184000347	Clp amino terminal domain; Region: Clp_N; pfam02861
707184000348	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184000349	Walker A motif; other site
707184000350	ATP binding site [chemical binding]; other site
707184000351	Walker B motif; other site
707184000352	arginine finger; other site
707184000353	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184000354	Walker A motif; other site
707184000355	ATP binding site [chemical binding]; other site
707184000356	Walker B motif; other site
707184000357	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
707184000358	Uncharacterized conserved protein [Function unknown]; Region: COG2912
707184000359	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
707184000360	IncA protein; Region: IncA; pfam04156
707184000361	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
707184000362	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
707184000363	substrate binding site [chemical binding]; other site
707184000364	hexamer interface [polypeptide binding]; other site
707184000365	metal binding site [ion binding]; metal-binding site
707184000366	elongation factor P; Provisional; Region: PRK12426
707184000367	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
707184000368	RNA binding site [nucleotide binding]; other site
707184000369	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
707184000370	RNA binding site [nucleotide binding]; other site
707184000371	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
707184000372	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
707184000373	carboxyltransferase (CT) interaction site; other site
707184000374	biotinylation site [posttranslational modification]; other site
707184000375	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
707184000376	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
707184000377	ATP-grasp domain; Region: ATP-grasp_4; cl17255
707184000378	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
707184000379	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
707184000380	23S rRNA interface [nucleotide binding]; other site
707184000381	L3 interface [polypeptide binding]; other site
707184000382	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
707184000383	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
707184000384	NlpC/P60 family; Region: NLPC_P60; cl17555
707184000385	adenylate kinase; Reviewed; Region: adk; PRK00279
707184000386	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
707184000387	AMP-binding site [chemical binding]; other site
707184000388	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
707184000389	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
707184000390	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707184000391	dimer interface [polypeptide binding]; other site
707184000392	conserved gate region; other site
707184000393	putative PBP binding loops; other site
707184000394	ABC-ATPase subunit interface; other site
707184000395	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
707184000396	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707184000397	Walker A/P-loop; other site
707184000398	ATP binding site [chemical binding]; other site
707184000399	Q-loop/lid; other site
707184000400	ABC transporter signature motif; other site
707184000401	Walker B; other site
707184000402	D-loop; other site
707184000403	H-loop/switch region; other site
707184000404	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
707184000405	Methyltransferase domain; Region: Methyltransf_23; pfam13489
707184000406	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707184000407	S-adenosylmethionine binding site [chemical binding]; other site
707184000408	RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner; Region: RNase_H; cl14782
707184000409	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
707184000410	Serine hydrolase (FSH1); Region: FSH1; pfam03959
707184000411	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
707184000412	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
707184000413	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
707184000414	active site
707184000415	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
707184000416	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
707184000417	conserved hypothetical integral membrane protein; Region: TIGR00697
707184000418	Predicted metal-binding protein related to the C-terminal domain of SecA [General function prediction only]; Region: COG3318
707184000419	SEC-C motif; Region: SEC-C; pfam02810
707184000420	potential protein location (hypothetical protein E150_00750 [Chlamydia trachomatis E/150]) that overlaps RNA (tRNA-T)
707184000421	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
707184000422	Catalytic domain of Protein Kinases; Region: PKc; cd00180
707184000423	active site
707184000424	ATP binding site [chemical binding]; other site
707184000425	substrate binding site [chemical binding]; other site
707184000426	activation loop (A-loop); other site
707184000427	Uncharacterized conserved protein [Function unknown]; Region: COG1262
707184000428	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
707184000429	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
707184000430	DNA ligase, NAD-dependent; Region: dnlj; TIGR00575
707184000431	nucleotide binding pocket [chemical binding]; other site
707184000432	K-X-D-G motif; other site
707184000433	catalytic site [active]
707184000434	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
707184000435	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
707184000436	Helix-hairpin-helix motif; Region: HHH; pfam00633
707184000437	helix-hairpin-helix signature motif; other site
707184000438	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
707184000439	Dimer interface [polypeptide binding]; other site
707184000440	BRCT sequence motif; other site
707184000441	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
707184000442	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
707184000443	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
707184000444	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
707184000445	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
707184000446	FtsX-like permease family; Region: FtsX; pfam02687
707184000447	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
707184000448	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
707184000449	Walker A/P-loop; other site
707184000450	ATP binding site [chemical binding]; other site
707184000451	Q-loop/lid; other site
707184000452	ABC transporter signature motif; other site
707184000453	Walker B; other site
707184000454	D-loop; other site
707184000455	H-loop/switch region; other site
707184000456	membrane-attack complex / perforin; Region: MACPF; smart00457
707184000457	Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; Region: MIR; smart00472
707184000458	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707184000459	PLD-like domain; Region: PLDc_2; pfam13091
707184000460	putative active site [active]
707184000461	catalytic site [active]
707184000462	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
707184000463	PLD-like domain; Region: PLDc_2; pfam13091
707184000464	putative active site [active]
707184000465	catalytic site [active]
707184000466	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707184000467	PLD-like domain; Region: PLDc_2; pfam13091
707184000468	putative active site [active]
707184000469	catalytic site [active]
707184000470	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707184000471	PLD-like domain; Region: PLDc_2; pfam13091
707184000472	putative active site [active]
707184000473	catalytic site [active]
707184000474	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707184000475	PLD-like domain; Region: PLDc_2; pfam13091
707184000476	putative active site [active]
707184000477	catalytic site [active]
707184000478	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
707184000479	PLD-like domain; Region: PLDc_2; pfam13091
707184000480	putative active site [active]
707184000481	catalytic site [active]
707184000482	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707184000483	potential frameshift: common BLAST hit: gi|15835056|ref|NP_296815.1| adherence factor
707184000484	TcdB toxin N-terminal helical domain; Region: TcdB_N; pfam12918
707184000485	TcdA/TcdB catalytic glycosyltransferase domain; Region: TcdA_TcdB; pfam12919
707184000486	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
707184000487	Protein of unknown function (DUF3491); Region: DUF3491; pfam11996
707184000488	trp operon repressor, proteobacterial; Region: TrpR; TIGR01321
707184000489	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
707184000490	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
707184000491	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707184000492	catalytic residue [active]
707184000493	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
707184000494	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
707184000495	substrate binding site [chemical binding]; other site
707184000496	active site
707184000497	catalytic residues [active]
707184000498	heterodimer interface [polypeptide binding]; other site
707184000499	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
707184000500	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
707184000501	peptide binding site [polypeptide binding]; other site
707184000502	putative disulfide oxidoreductase; Provisional; Region: PRK00611
707184000503	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
707184000504	Thioredoxin; Region: Thioredoxin_4; cl17273
707184000505	Vitamin K epoxide reductase (VKOR) family; Region: VKOR; cl01729
707184000506	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
707184000507	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707184000508	Walker A/P-loop; other site
707184000509	ATP binding site [chemical binding]; other site
707184000510	Q-loop/lid; other site
707184000511	ABC transporter signature motif; other site
707184000512	Walker B; other site
707184000513	D-loop; other site
707184000514	H-loop/switch region; other site
707184000515	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
707184000516	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
707184000517	Ligand binding site; other site
707184000518	oligomer interface; other site
707184000519	CTP synthetase; Validated; Region: pyrG; PRK05380
707184000520	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
707184000521	Catalytic site [active]
707184000522	active site
707184000523	UTP binding site [chemical binding]; other site
707184000524	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
707184000525	active site
707184000526	putative oxyanion hole; other site
707184000527	catalytic triad [active]
707184000528	Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) [DNA replication, recombination, and repair]; Region: COG0816
707184000529	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
707184000530	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
707184000531	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
707184000532	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
707184000533	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
707184000534	putative active site [active]
707184000535	DNA polymerase III subunit delta'; Validated; Region: PRK05917
707184000536	DNA polymerase III subunit delta'; Validated; Region: PRK08485
707184000537	thymidylate kinase; Validated; Region: tmk; PRK00698
707184000538	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
707184000539	TMP-binding site; other site
707184000540	ATP-binding site [chemical binding]; other site
707184000541	DNA gyrase, A subunit; Region: gyrA; TIGR01063
707184000542	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
707184000543	CAP-like domain; other site
707184000544	active site
707184000545	primary dimer interface [polypeptide binding]; other site
707184000546	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707184000547	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707184000548	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707184000549	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707184000550	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707184000551	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707184000552	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
707184000553	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707184000554	ATP binding site [chemical binding]; other site
707184000555	Mg2+ binding site [ion binding]; other site
707184000556	G-X-G motif; other site
707184000557	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
707184000558	anchoring element; other site
707184000559	dimer interface [polypeptide binding]; other site
707184000560	ATP binding site [chemical binding]; other site
707184000561	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
707184000562	active site
707184000563	putative metal-binding site [ion binding]; other site
707184000564	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
707184000565	Protein of unknown function (DUF721); Region: DUF721; pfam05258
707184000566	queuine tRNA-ribosyltransferase; Provisional; Region: PRK01008
707184000567	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
707184000568	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
707184000569	MgtE intracellular N domain; Region: MgtE_N; pfam03448
707184000570	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
707184000571	Divalent cation transporter; Region: MgtE; pfam01769
707184000572	UGMP family protein; Validated; Region: PRK09604
707184000573	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
707184000574	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
707184000575	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
707184000576	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
707184000577	peptide binding site [polypeptide binding]; other site
707184000578	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
707184000579	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707184000580	dimer interface [polypeptide binding]; other site
707184000581	conserved gate region; other site
707184000582	putative PBP binding loops; other site
707184000583	ABC-ATPase subunit interface; other site
707184000584	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
707184000585	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707184000586	dimer interface [polypeptide binding]; other site
707184000587	conserved gate region; other site
707184000588	putative PBP binding loops; other site
707184000589	ABC-ATPase subunit interface; other site
707184000590	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707184000591	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
707184000592	Walker A/P-loop; other site
707184000593	ATP binding site [chemical binding]; other site
707184000594	Q-loop/lid; other site
707184000595	ABC transporter signature motif; other site
707184000596	Walker B; other site
707184000597	D-loop; other site
707184000598	H-loop/switch region; other site
707184000599	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
707184000600	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
707184000601	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707184000602	Walker A/P-loop; other site
707184000603	ATP binding site [chemical binding]; other site
707184000604	Q-loop/lid; other site
707184000605	ABC transporter signature motif; other site
707184000606	Walker B; other site
707184000607	D-loop; other site
707184000608	H-loop/switch region; other site
707184000609	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
707184000610	Protein of unknown function (DUF1186); Region: DUF1186; pfam06685
707184000611	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
707184000612	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
707184000613	transmembrane helices; other site
707184000614	diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional; Region: PRK07085
707184000615	active site
707184000616	ADP/pyrophosphate binding site [chemical binding]; other site
707184000617	dimerization interface [polypeptide binding]; other site
707184000618	allosteric effector site; other site
707184000619	fructose-1,6-bisphosphate binding site; other site
707184000620	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
707184000621	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
707184000622	diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional; Region: PRK07085
707184000623	pyrophosphate-dependent phosphofructokinase; Region: PLN02251
707184000624	active site
707184000625	ADP/pyrophosphate binding site [chemical binding]; other site
707184000626	dimerization interface [polypeptide binding]; other site
707184000627	allosteric effector site; other site
707184000628	fructose-1,6-bisphosphate binding site; other site
707184000629	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
707184000630	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
707184000631	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
707184000632	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
707184000633	HIGH motif; other site
707184000634	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
707184000635	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
707184000636	active site
707184000637	KMSKS motif; other site
707184000638	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
707184000639	tRNA binding surface [nucleotide binding]; other site
707184000640	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00615
707184000641	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
707184000642	inhibitor-cofactor binding pocket; inhibition site
707184000643	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707184000644	catalytic residue [active]
707184000645	Putative transcriptional regulator [Transcription]; Region: COG1678
707184000646	Uncharacterized conserved protein [Function unknown]; Region: COG1259
707184000647	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
707184000648	tetramer (dimer of dimers) interface [polypeptide binding]; other site
707184000649	active site
707184000650	dimer interface [polypeptide binding]; other site
707184000651	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
707184000652	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
707184000653	putative active site; other site
707184000654	catalytic residue [active]
707184000655	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
707184000656	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
707184000657	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
707184000658	Ligand Binding Site [chemical binding]; other site
707184000659	Predicted acid phosphatase [General function prediction only]; Region: SurE; COG0496
707184000660	prenyltransferase; Reviewed; Region: ubiA; PRK12876
707184000661	UbiA prenyltransferase family; Region: UbiA; pfam01040
707184000662	aromatic acid decarboxylase; Validated; Region: PRK05920
707184000663	Flavoprotein; Region: Flavoprotein; pfam02441
707184000664	Uncharacterized conserved protein [Function unknown]; Region: COG1284
707184000665	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
707184000666	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
707184000667	IncA protein; Region: IncA; pfam04156
707184000668	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
707184000669	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
707184000670	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
707184000671	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
707184000672	Na2 binding site [ion binding]; other site
707184000673	putative substrate binding site 1 [chemical binding]; other site
707184000674	Na binding site 1 [ion binding]; other site
707184000675	putative substrate binding site 2 [chemical binding]; other site
707184000676	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707184000677	putative substrate translocation pore; other site
707184000678	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
707184000679	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
707184000680	ligand binding site [chemical binding]; other site
707184000681	flexible hinge region; other site
707184000682	acyl carrier protein; Provisional; Region: acpP; PRK00982
707184000683	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
707184000684	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
707184000685	NAD(P) binding site [chemical binding]; other site
707184000686	homotetramer interface [polypeptide binding]; other site
707184000687	homodimer interface [polypeptide binding]; other site
707184000688	active site
707184000689	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
707184000690	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
707184000691	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
707184000692	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
707184000693	dimer interface [polypeptide binding]; other site
707184000694	active site
707184000695	CoA binding pocket [chemical binding]; other site
707184000696	recombination protein RecR; Region: recR; TIGR00615
707184000697	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
707184000698	putative active site [active]
707184000699	putative metal-binding site [ion binding]; other site
707184000700	tetramer interface [polypeptide binding]; other site
707184000701	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
707184000702	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707184000703	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707184000704	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707184000705	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707184000706	Surface antigen; Region: Bac_surface_Ag; pfam01103
707184000707	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: HlpA; COG2825
707184000708	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
707184000709	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
707184000710	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
707184000711	trimer interface [polypeptide binding]; other site
707184000712	active site
707184000713	UDP-GlcNAc binding site [chemical binding]; other site
707184000714	lipid binding site [chemical binding]; lipid-binding site
707184000715	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
707184000716	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
707184000717	tetramer interface [polypeptide binding]; other site
707184000718	TPP-binding site [chemical binding]; other site
707184000719	heterodimer interface [polypeptide binding]; other site
707184000720	phosphorylation loop region [posttranslational modification]
707184000721	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
707184000722	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
707184000723	alpha subunit interface [polypeptide binding]; other site
707184000724	TPP binding site [chemical binding]; other site
707184000725	heterodimer interface [polypeptide binding]; other site
707184000726	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707184000727	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; Region: PDHac_trf_mito; TIGR01349
707184000728	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
707184000729	E3 interaction surface; other site
707184000730	lipoyl attachment site [posttranslational modification]; other site
707184000731	e3 binding domain; Region: E3_binding; pfam02817
707184000732	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
707184000733	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
707184000734	homodimer interface [polypeptide binding]; other site
707184000735	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
707184000736	active site pocket [active]
707184000737	chromosomal replication initiation protein; Provisional; Region: PRK12422
707184000738	DnaA N-terminal domain; Region: DnaA_N; pfam11638
707184000739	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184000740	Walker A motif; other site
707184000741	ATP binding site [chemical binding]; other site
707184000742	Walker B motif; other site
707184000743	arginine finger; other site
707184000744	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
707184000745	DnaA box-binding interface [nucleotide binding]; other site
707184000746	putative inner membrane protein translocase component YidC; Provisional; Region: PRK01001
707184000747	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
707184000748	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
707184000749	CAAX protease self-immunity; Region: Abi; pfam02517
707184000750	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
707184000751	homodimer interface [polypeptide binding]; other site
707184000752	metal binding site [ion binding]; metal-binding site
707184000753	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
707184000754	Domain of unknown function DUF21; Region: DUF21; pfam01595
707184000755	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
707184000756	Transporter associated domain; Region: CorC_HlyC; smart01091
707184000757	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
707184000758	Domain of unknown function DUF21; Region: DUF21; pfam01595
707184000759	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
707184000760	Transporter associated domain; Region: CorC_HlyC; smart01091
707184000761	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
707184000762	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
707184000763	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707184000764	catalytic residue [active]
707184000765	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
707184000766	Protein phosphatase 2C; Region: PP2C; pfam00481
707184000767	active site
707184000768	Uncharacterized conserved protein [Function unknown]; Region: COG5465
707184000769	DNA polymerase III subunit epsilon; Validated; Region: PRK06309
707184000770	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
707184000771	active site
707184000772	catalytic site [active]
707184000773	substrate binding site [chemical binding]; other site
707184000774	Protein of unknown function (DUF3820); Region: DUF3820; cl01411
707184000775	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
707184000776	nucleosidase; Provisional; Region: PRK05634
707184000777	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
707184000778	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
707184000779	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707184000780	Walker A/P-loop; other site
707184000781	ATP binding site [chemical binding]; other site
707184000782	Q-loop/lid; other site
707184000783	ABC transporter signature motif; other site
707184000784	Walker B; other site
707184000785	D-loop; other site
707184000786	H-loop/switch region; other site
707184000787	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
707184000788	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
707184000789	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
707184000790	IHF - DNA interface [nucleotide binding]; other site
707184000791	IHF dimer interface [polypeptide binding]; other site
707184000792	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
707184000793	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
707184000794	active site
707184000795	metal binding site [ion binding]; metal-binding site
707184000796	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
707184000797	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
707184000798	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707184000799	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707184000800	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
707184000801	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
707184000802	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
707184000803	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
707184000804	MraW methylase family; Region: Methyltransf_5; pfam01795
707184000805	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707184000806	TPR motif; other site
707184000807	binding surface
707184000808	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
707184000809	DnaA N-terminal domain; Region: DnaA_N; pfam11638
707184000810	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184000811	Walker A motif; other site
707184000812	ATP binding site [chemical binding]; other site
707184000813	Walker B motif; other site
707184000814	arginine finger; other site
707184000815	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
707184000816	DnaA box-binding interface [nucleotide binding]; other site
707184000817	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
707184000818	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
707184000819	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK01024
707184000820	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC [Energy production and conversion]; Region: NqrC; COG2869
707184000821	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
707184000822	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD [Energy production and conversion]; Region: NqrD; COG1347
707184000823	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK01061
707184000824	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
707184000825	lipoyl attachment site [posttranslational modification]; other site
707184000826	Chlamydial GcvH-like protein upstream region protein; Region: near_not_gcvH; TIGR03076
707184000827	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
707184000828	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707184000829	putative active site [active]
707184000830	catalytic site [active]
707184000831	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707184000832	putative active site [active]
707184000833	catalytic site [active]
707184000834	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
707184000835	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
707184000836	Clp amino terminal domain; Region: Clp_N; pfam02861
707184000837	Clp amino terminal domain; Region: Clp_N; pfam02861
707184000838	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184000839	Walker A motif; other site
707184000840	ATP binding site [chemical binding]; other site
707184000841	Walker B motif; other site
707184000842	arginine finger; other site
707184000843	UvrB/uvrC motif; Region: UVR; pfam02151
707184000844	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184000845	Walker A motif; other site
707184000846	ATP binding site [chemical binding]; other site
707184000847	Walker B motif; other site
707184000848	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
707184000849	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
707184000850	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
707184000851	Ligand Binding Site [chemical binding]; other site
707184000852	Helix-turn-helix domain; Region: HTH_17; pfam12728
707184000853	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
707184000854	active site
707184000855	phosphorylation site [posttranslational modification]
707184000856	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
707184000857	active site
707184000858	phosphorylation site [posttranslational modification]
707184000859	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
707184000860	trimer interface [polypeptide binding]; other site
707184000861	active site
707184000862	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
707184000863	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
707184000864	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
707184000865	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
707184000866	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
707184000867	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
707184000868	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
707184000869	active site
707184000870	substrate binding site [chemical binding]; other site
707184000871	metal binding site [ion binding]; metal-binding site
707184000872	ribonuclease III; Reviewed; Region: rnc; PRK00102
707184000873	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
707184000874	dimerization interface [polypeptide binding]; other site
707184000875	active site
707184000876	metal binding site [ion binding]; metal-binding site
707184000877	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
707184000878	dsRNA binding site [nucleotide binding]; other site
707184000879	DNA repair protein RadA; Provisional; Region: PRK11823
707184000880	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
707184000881	Walker A motif/ATP binding site; other site
707184000882	ATP binding site [chemical binding]; other site
707184000883	Walker B motif; other site
707184000884	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
707184000885	porphobilinogen deaminase; Provisional; Region: PRK01066
707184000886	Porphobilinogen deaminase, dipyromethane cofactor binding domain; Region: Porphobil_deam; pfam01379
707184000887	serine/threonine-protein kinase; Reviewed; Region: pknD; PRK13184
707184000888	Catalytic domain of Protein Kinases; Region: PKc; cd00180
707184000889	active site
707184000890	ATP binding site [chemical binding]; other site
707184000891	substrate binding site [chemical binding]; other site
707184000892	activation loop (A-loop); other site
707184000893	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
707184000894	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
707184000895	HIGH motif; other site
707184000896	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
707184000897	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
707184000898	active site
707184000899	KMSKS motif; other site
707184000900	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
707184000901	tRNA binding surface [nucleotide binding]; other site
707184000902	anticodon binding site; other site
707184000903	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
707184000904	V-type ATP synthase subunit K; Provisional; Region: PRK09621
707184000905	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
707184000906	V-type ATP synthase subunit I; Validated; Region: PRK05771
707184000907	Protein of unknown function (DUF1319); Region: DUF1319; pfam07028
707184000908	V-type ATP synthase subunit D; Provisional; Region: PRK02195
707184000909	V-type ATP synthase subunit B; Provisional; Region: PRK02118
707184000910	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707184000911	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
707184000912	Walker A motif homologous position; other site
707184000913	Walker B motif; other site
707184000914	V-type ATP synthase subunit A; Provisional; Region: PRK04192
707184000915	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707184000916	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
707184000917	Walker A motif/ATP binding site; other site
707184000918	Walker B motif; other site
707184000919	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
707184000920	Protein of unknown function (DUF2764); Region: DUF2764; pfam10962
707184000921	V-type ATP synthase subunit E; Provisional; Region: PRK01005
707184000922	V-type ATP synthase subunit E; Provisional; Region: PRK01558
707184000923	transaldolase-like protein; Provisional; Region: PTZ00411
707184000924	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
707184000925	active site
707184000926	dimer interface [polypeptide binding]; other site
707184000927	catalytic residue [active]
707184000928	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
707184000929	DNA-directed RNA polymerase, beta' subunit, predominant form; Region: rpoC_TIGR; TIGR02386
707184000930	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
707184000931	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
707184000932	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
707184000933	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
707184000934	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
707184000935	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
707184000936	DNA binding site [nucleotide binding]
707184000937	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
707184000938	RNA polymerase beta subunit; Region: RNA_pol_Rpb2_1; pfam04563
707184000939	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
707184000940	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
707184000941	DNA-directed RNA polymerase, beta subunit; Region: rpoB; TIGR02013
707184000942	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
707184000943	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
707184000944	RPB12 interaction site [polypeptide binding]; other site
707184000945	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
707184000946	RPB3 interaction site [polypeptide binding]; other site
707184000947	RPB1 interaction site [polypeptide binding]; other site
707184000948	RPB11 interaction site [polypeptide binding]; other site
707184000949	RPB10 interaction site [polypeptide binding]; other site
707184000950	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
707184000951	L11 interface [polypeptide binding]; other site
707184000952	putative EF-Tu interaction site [polypeptide binding]; other site
707184000953	putative EF-G interaction site [polypeptide binding]; other site
707184000954	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
707184000955	23S rRNA interface [nucleotide binding]; other site
707184000956	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
707184000957	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
707184000958	mRNA/rRNA interface [nucleotide binding]; other site
707184000959	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
707184000960	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
707184000961	putative thiostrepton binding site; other site
707184000962	23S rRNA interface [nucleotide binding]; other site
707184000963	L7/L12 interface [polypeptide binding]; other site
707184000964	L25 interface [polypeptide binding]; other site
707184000965	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
707184000966	transcription termination/antitermination factor NusG; Region: nusG; TIGR00922
707184000967	putative homodimer interface [polypeptide binding]; other site
707184000968	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
707184000969	heterodimer interface [polypeptide binding]; other site
707184000970	homodimer interface [polypeptide binding]; other site
707184000971	Preprotein translocase subunit SecE [Intracellular trafficking and secretion]; Region: SecE; COG0690
707184000972	elongation factor Tu; Reviewed; Region: PRK12735
707184000973	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
707184000974	G1 box; other site
707184000975	GEF interaction site [polypeptide binding]; other site
707184000976	GTP/Mg2+ binding site [chemical binding]; other site
707184000977	Switch I region; other site
707184000978	G2 box; other site
707184000979	G3 box; other site
707184000980	Switch II region; other site
707184000981	G4 box; other site
707184000982	G5 box; other site
707184000983	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
707184000984	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
707184000985	Antibiotic Binding Site [chemical binding]; other site
707184000986	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
707184000987	rRNA binding site [nucleotide binding]; other site
707184000988	predicted 30S ribosome binding site; other site
707184000989	Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]; Region: sufE; COG2166
707184000990	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
707184000991	active site
707184000992	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
707184000993	triosephosphate isomerase; Provisional; Region: PRK14565
707184000994	substrate binding site [chemical binding]; other site
707184000995	dimer interface [polypeptide binding]; other site
707184000996	catalytic triad [active]
707184000997	Exonuclease VII, large subunit [DNA replication, recombination, and repair]; Region: XseA; COG1570
707184000998	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
707184000999	generic binding surface II; other site
707184001000	generic binding surface I; other site
707184001001	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
707184001002	Deoxyxylulose-5-phosphate synthase [Coenzyme metabolism / Lipid metabolism]; Region: Dxs; COG1154
707184001003	1-deoxy-D-xylulose-5-phosphate synthase; Region: DXP_synthase_N; pfam13292
707184001004	TPP-binding site [chemical binding]; other site
707184001005	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
707184001006	PYR/PP interface [polypeptide binding]; other site
707184001007	dimer interface [polypeptide binding]; other site
707184001008	TPP binding site [chemical binding]; other site
707184001009	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707184001010	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
707184001011	pyruvate kinase; Region: pyruv_kin; TIGR01064
707184001012	domain interfaces; other site
707184001013	active site
707184001014	excinuclease ABC subunit A; Provisional; Region: PRK00635
707184001015	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707184001016	Walker A/P-loop; other site
707184001017	ATP binding site [chemical binding]; other site
707184001018	Q-loop/lid; other site
707184001019	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
707184001020	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
707184001021	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707184001022	Walker A/P-loop; other site
707184001023	ATP binding site [chemical binding]; other site
707184001024	Q-loop/lid; other site
707184001025	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707184001026	ABC transporter signature motif; other site
707184001027	Walker B; other site
707184001028	D-loop; other site
707184001029	H-loop/switch region; other site
707184001030	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707184001031	Walker A/P-loop; other site
707184001032	ATP binding site [chemical binding]; other site
707184001033	Q-loop/lid; other site
707184001034	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707184001035	Q-loop/lid; other site
707184001036	ABC transporter signature motif; other site
707184001037	Walker B; other site
707184001038	D-loop; other site
707184001039	H-loop/switch region; other site
707184001040	DNA polymerase III subunits gamma and tau; Validated; Region: PRK06305
707184001041	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184001042	Walker A motif; other site
707184001043	ATP binding site [chemical binding]; other site
707184001044	Walker B motif; other site
707184001045	arginine finger; other site
707184001046	hypothetical protein; Validated; Region: PRK00153
707184001047	phosphoenolpyruvate-protein phosphotransferase; Region: PTS_I_fam; TIGR01417
707184001048	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
707184001049	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
707184001050	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
707184001051	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
707184001052	dimerization domain swap beta strand [polypeptide binding]; other site
707184001053	regulatory protein interface [polypeptide binding]; other site
707184001054	active site
707184001055	regulatory phosphorylation site [posttranslational modification]; other site
707184001056	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
707184001057	Competence protein; Region: Competence; pfam03772
707184001058	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
707184001059	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
707184001060	tetramer interface [polypeptide binding]; other site
707184001061	TPP-binding site [chemical binding]; other site
707184001062	heterodimer interface [polypeptide binding]; other site
707184001063	phosphorylation loop region [posttranslational modification]
707184001064	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
707184001065	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
707184001066	alpha subunit interface [polypeptide binding]; other site
707184001067	TPP binding site [chemical binding]; other site
707184001068	heterodimer interface [polypeptide binding]; other site
707184001069	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707184001070	chaperone protein DnaJ; Provisional; Region: PRK14284
707184001071	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
707184001072	HSP70 interaction site [polypeptide binding]; other site
707184001073	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
707184001074	Zn binding sites [ion binding]; other site
707184001075	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
707184001076	dimer interface [polypeptide binding]; other site
707184001077	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
707184001078	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
707184001079	Glycoprotease family; Region: Peptidase_M22; pfam00814
707184001080	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
707184001081	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184001082	Walker A motif; other site
707184001083	ATP binding site [chemical binding]; other site
707184001084	Walker B motif; other site
707184001085	arginine finger; other site
707184001086	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
707184001087	ribonuclease Z; Region: RNase_Z; TIGR02651
707184001088	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
707184001089	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
707184001090	active site
707184001091	Int/Topo IB signature motif; other site
707184001092	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
707184001093	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
707184001094	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
707184001095	ABC transporter; Region: ABC_tran_2; pfam12848
707184001096	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
707184001097	Maf-like protein; Region: Maf; pfam02545
707184001098	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
707184001099	active site
707184001100	dimer interface [polypeptide binding]; other site
707184001101	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
707184001102	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
707184001103	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
707184001104	active site
707184001105	catalytic residues [active]
707184001106	metal binding site [ion binding]; metal-binding site
707184001107	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
707184001108	dimethyladenosine transferase; Region: ksgA; TIGR00755
707184001109	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
707184001110	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
707184001111	catalytic residues [active]
707184001112	potential protein location (hypothetical protein E150_01870 [Chlamydia trachomatis E/150]) that overlaps RNA (tRNA-S)
707184001113	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
707184001114	dihydrodipicolinate synthase; Region: dapA; TIGR00674
707184001115	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
707184001116	inhibitor site; inhibition site
707184001117	active site
707184001118	dimer interface [polypeptide binding]; other site
707184001119	catalytic residue [active]
707184001120	aspartate kinase; Provisional; Region: PRK05925
707184001121	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
707184001122	putative catalytic residues [active]
707184001123	nucleotide binding site [chemical binding]; other site
707184001124	aspartate binding site [chemical binding]; other site
707184001125	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK08664
707184001126	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
707184001127	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
707184001128	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
707184001129	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
707184001130	5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; Region: AroA; COG0128
707184001131	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
707184001132	hinge; other site
707184001133	active site
707184001134	shikimate kinase; Provisional; Region: PRK00625
707184001135	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
707184001136	ADP binding site [chemical binding]; other site
707184001137	magnesium binding site [ion binding]; other site
707184001138	putative shikimate binding site; other site
707184001139	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
707184001140	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
707184001141	Tetramer interface [polypeptide binding]; other site
707184001142	active site
707184001143	FMN-binding site [chemical binding]; other site
707184001144	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
707184001145	active site
707184001146	dimer interface [polypeptide binding]; other site
707184001147	metal binding site [ion binding]; metal-binding site
707184001148	bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase protein; Reviewed; Region: aroDE; PRK09310
707184001149	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
707184001150	active site
707184001151	catalytic residue [active]
707184001152	dimer interface [polypeptide binding]; other site
707184001153	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
707184001154	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
707184001155	shikimate binding site; other site
707184001156	NAD(P) binding site [chemical binding]; other site
707184001157	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
707184001158	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
707184001159	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) [Amino acid    transport and metabolism]; Region: COG1945
707184001160	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
707184001161	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
707184001162	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
707184001163	malate dehydrogenase; Provisional; Region: PRK05442
707184001164	Chloroplast-like malate dehydrogenases; Region: MDH_choloroplast_like; cd01338
707184001165	NAD(P) binding site [chemical binding]; other site
707184001166	dimer interface [polypeptide binding]; other site
707184001167	malate binding site [chemical binding]; other site
707184001168	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14095
707184001169	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
707184001170	active site
707184001171	dimer interface [polypeptide binding]; other site
707184001172	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
707184001173	dimer interface [polypeptide binding]; other site
707184001174	active site
707184001175	GTPases [General function prediction only]; Region: HflX; COG2262
707184001176	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
707184001177	HflX GTPase family; Region: HflX; cd01878
707184001178	G1 box; other site
707184001179	GTP/Mg2+ binding site [chemical binding]; other site
707184001180	Switch I region; other site
707184001181	G2 box; other site
707184001182	G3 box; other site
707184001183	Switch II region; other site
707184001184	G4 box; other site
707184001185	G5 box; other site
707184001186	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
707184001187	putative hydrolase; Provisional; Region: PRK02113
707184001188	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
707184001189	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
707184001190	substrate binding pocket [chemical binding]; other site
707184001191	membrane-bound complex binding site; other site
707184001192	hinge residues; other site
707184001193	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroA; COG2876
707184001194	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
707184001195	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
707184001196	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
707184001197	nucleotide binding site/active site [active]
707184001198	Uncharacterized conserved protein related to MYG1 family [Function unknown]; Region: COG4286
707184001199	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
707184001200	hypothetical protein; Validated; Region: PRK00647
707184001201	Protein of unknown function (DUF1207); Region: DUF1207; pfam06727
707184001202	LL-diaminopimelate aminotransferase; Region: DAPAT_plant; TIGR03542
707184001203	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
707184001204	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707184001205	homodimer interface [polypeptide binding]; other site
707184001206	catalytic residue [active]
707184001207	ABC transporter substrate binding protein; Region: ABC_sub_bind; pfam04392
707184001208	prolyl-tRNA synthetase; Provisional; Region: PRK09194
707184001209	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
707184001210	dimer interface [polypeptide binding]; other site
707184001211	motif 1; other site
707184001212	active site
707184001213	motif 2; other site
707184001214	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
707184001215	putative deacylase active site [active]
707184001216	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
707184001217	active site
707184001218	motif 3; other site
707184001219	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
707184001220	anticodon binding site; other site
707184001221	Transcriptional regulator of heat shock gene [Transcription]; Region: HrcA; COG1420
707184001222	GrpE; Region: GrpE; pfam01025
707184001223	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
707184001224	dimer interface [polypeptide binding]; other site
707184001225	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
707184001226	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
707184001227	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
707184001228	nucleotide binding site [chemical binding]; other site
707184001229	NEF interaction site [polypeptide binding]; other site
707184001230	SBD interface [polypeptide binding]; other site
707184001231	Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]; Region: NtpF; COG2811
707184001232	Exoribonuclease R [Transcription]; Region: VacB; COG0557
707184001233	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
707184001234	RNB domain; Region: RNB; pfam00773
707184001235	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
707184001236	Putative zinc ribbon domain; Region: DUF164; pfam02591
707184001237	KpsF/GutQ family protein; Region: kpsF; TIGR00393
707184001238	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
707184001239	putative active site [active]
707184001240	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
707184001241	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
707184001242	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
707184001243	E3 interaction surface; other site
707184001244	lipoyl attachment site [posttranslational modification]; other site
707184001245	e3 binding domain; Region: E3_binding; pfam02817
707184001246	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
707184001247	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
707184001248	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
707184001249	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
707184001250	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
707184001251	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
707184001252	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
707184001253	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
707184001254	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
707184001255	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707184001256	S-adenosylmethionine binding site [chemical binding]; other site
707184001257	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
707184001258	Lumazine binding domain; Region: Lum_binding; pfam00677
707184001259	Lumazine binding domain; Region: Lum_binding; pfam00677
707184001260	Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains [Transcription]; Region: COG1327
707184001261	ATP cone domain; Region: ATP-cone; pfam03477
707184001262	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
707184001263	Lipoprotein signal peptidase [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: LspA; COG0597
707184001264	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
707184001265	amino acid carrier protein; Region: agcS; TIGR00835
707184001266	poly(A) polymerase; Region: pcnB; TIGR01942
707184001267	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
707184001268	active site
707184001269	NTP binding site [chemical binding]; other site
707184001270	metal binding triad [ion binding]; metal-binding site
707184001271	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
707184001272	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK01021
707184001273	Lipid A Biosynthesis N-terminal domain; Region: LAB_N; pfam07578
707184001274	Predicted membrane protein [Function unknown]; Region: COG3952
707184001275	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
707184001276	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707184001277	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707184001278	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707184001279	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707184001280	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707184001281	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707184001282	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707184001283	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707184001284	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
707184001285	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
707184001286	intersubunit interface [polypeptide binding]; other site
707184001287	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707184001288	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
707184001289	Walker A/P-loop; other site
707184001290	ATP binding site [chemical binding]; other site
707184001291	Q-loop/lid; other site
707184001292	ABC transporter signature motif; other site
707184001293	Walker B; other site
707184001294	D-loop; other site
707184001295	H-loop/switch region; other site
707184001296	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
707184001297	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
707184001298	ABC-ATPase subunit  interface; other site
707184001299	dimer interface [polypeptide binding]; other site
707184001300	putative PBP binding regions; other site
707184001301	GTPase CgtA; Reviewed; Region: obgE; PRK12299
707184001302	GTP1/OBG; Region: GTP1_OBG; pfam01018
707184001303	Obg GTPase; Region: Obg; cd01898
707184001304	G1 box; other site
707184001305	GTP/Mg2+ binding site [chemical binding]; other site
707184001306	Switch I region; other site
707184001307	G2 box; other site
707184001308	G3 box; other site
707184001309	Switch II region; other site
707184001310	G4 box; other site
707184001311	G5 box; other site
707184001312	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
707184001313	Ribosomal protein L21 [Translation, ribosomal structure and biogenesis]; Region: RplU; COG0261
707184001314	Uncharacterized conserved protein [Function unknown]; Region: COG2928
707184001315	Chlam_Verruc_Plancto small basic protein; Region: Chlam_Ver_rRNA; TIGR04137
707184001316	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG0319
707184001317	FOG: CBS domain [General function prediction only]; Region: COG0517
707184001318	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
707184001319	Transporter associated domain; Region: CorC_HlyC; smart01091
707184001320	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
707184001321	anti sigma factor interaction site; other site
707184001322	regulatory phosphorylation site [posttranslational modification]; other site
707184001323	Protein of unknown function (DUF3604); Region: DUF3604; pfam12228
707184001324	hypothetical protein; Provisional; Region: PRK05926
707184001325	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
707184001326	FeS/SAM binding site; other site
707184001327	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
707184001328	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
707184001329	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707184001330	S-adenosylmethionine binding site [chemical binding]; other site
707184001331	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
707184001332	Uncharacterized protein family (UPF0158); Region: UPF0158; pfam03682
707184001333	diaminopimelate epimerase; Region: DapF; TIGR00652
707184001334	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
707184001335	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
707184001336	ATP-dependent Clp protease proteolytic subunit; Reviewed; Region: PRK12553
707184001337	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
707184001338	oligomer interface [polypeptide binding]; other site
707184001339	active site residues [active]
707184001340	serine hydroxymethyltransferase; Provisional; Region: PRK13580
707184001341	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
707184001342	dimer interface [polypeptide binding]; other site
707184001343	active site
707184001344	glycine-pyridoxal phosphate binding site [chemical binding]; other site
707184001345	folate binding site [chemical binding]; other site
707184001346	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
707184001347	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
707184001348	active site
707184001349	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
707184001350	homotrimer interaction site [polypeptide binding]; other site
707184001351	zinc binding site [ion binding]; other site
707184001352	CDP-binding sites; other site
707184001353	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
707184001354	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
707184001355	FAD binding pocket [chemical binding]; other site
707184001356	conserved FAD binding motif [chemical binding]; other site
707184001357	phosphate binding motif [ion binding]; other site
707184001358	beta-alpha-beta structure motif; other site
707184001359	NAD binding pocket [chemical binding]; other site
707184001360	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
707184001361	elongation factor G; Reviewed; Region: PRK12739
707184001362	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
707184001363	G1 box; other site
707184001364	putative GEF interaction site [polypeptide binding]; other site
707184001365	GTP/Mg2+ binding site [chemical binding]; other site
707184001366	Switch I region; other site
707184001367	G2 box; other site
707184001368	G3 box; other site
707184001369	Switch II region; other site
707184001370	G4 box; other site
707184001371	G5 box; other site
707184001372	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
707184001373	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
707184001374	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
707184001375	30S ribosomal protein S7; Validated; Region: PRK05302
707184001376	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
707184001377	S17 interaction site [polypeptide binding]; other site
707184001378	S8 interaction site; other site
707184001379	16S rRNA interaction site [nucleotide binding]; other site
707184001380	streptomycin interaction site [chemical binding]; other site
707184001381	23S rRNA interaction site [nucleotide binding]; other site
707184001382	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
707184001383	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
707184001384	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
707184001385	protein binding site [polypeptide binding]; other site
707184001386	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
707184001387	Catalytic dyad [active]
707184001388	Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA); Region: CRPA; pfam05745
707184001389	Chlamydia cysteine-rich outer membrane protein 6; Region: Chlam_OMP6; pfam03504
707184001390	Domain of unknown function DUF11; Region: DUF11; pfam01345
707184001391	Domain of unknown function DUF11; Region: DUF11; pfam01345
707184001392	Chlamydia cysteine-rich outer membrane protein 3; Region: Chlam_OMP3; pfam03503
707184001393	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
707184001394	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
707184001395	HIGH motif; other site
707184001396	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
707184001397	active site
707184001398	KMSKS motif; other site
707184001399	Helix-turn-helix domain; Region: HTH_17; pfam12728
707184001400	Helix-turn-helix domain; Region: HTH_17; pfam12728
707184001401	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
707184001402	DHH family; Region: DHH; pfam01368
707184001403	DHHA1 domain; Region: DHHA1; pfam02272
707184001404	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK12911
707184001405	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
707184001406	Protein export membrane protein; Region: SecD_SecF; pfam02355
707184001407	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14840
707184001408	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
707184001409	catalytic residue [active]
707184001410	putative FPP diphosphate  binding site; other site
707184001411	putative FPP binding hydrophobic cleft; other site
707184001412	dimer interface [polypeptide binding]; other site
707184001413	putative IPP diphosphate binding site; other site
707184001414	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
707184001415	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
707184001416	Cytidylate kinase [Nucleotide transport and metabolism]; Region: Cmk; COG0283
707184001417	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
707184001418	CMP-binding site; other site
707184001419	The sites determining sugar specificity; other site
707184001420	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
707184001421	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
707184001422	putative acyl-acceptor binding pocket; other site
707184001423	arginine-tRNA ligase; Region: PLN02286
707184001424	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
707184001425	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
707184001426	active site
707184001427	HIGH motif; other site
707184001428	KMSK motif region; other site
707184001429	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
707184001430	tRNA binding surface [nucleotide binding]; other site
707184001431	anticodon binding site; other site
707184001432	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
707184001433	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
707184001434	hinge; other site
707184001435	active site
707184001436	Domain of Unknown Function (DUF1547); Region: DUF1547; pfam07577
707184001437	Domain of Unknown Function (DUF1547); Region: DUF1547; pfam07577
707184001438	Domain of Unknown Function (DUF1547); Region: DUF1547; pfam07577
707184001439	DNA-binding regulatory protein, YebC/PmpR family; Region: TIGR01033
707184001440	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
707184001441	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
707184001442	Coenzyme A binding pocket [chemical binding]; other site
707184001443	PCRF domain; Region: PCRF; pfam03462
707184001444	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
707184001445	RF-1 domain; Region: RF-1; pfam00472
707184001446	SWIB-domain-containing proteins implicated in chromatin remodeling [Chromatin structure and dynamics]; Region: COG5531
707184001447	SWI complex, BAF60b domains; Region: SWIB; smart00151
707184001448	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
707184001449	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
707184001450	putative active site [active]
707184001451	putative metal binding site [ion binding]; other site
707184001452	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
707184001453	substrate binding site; other site
707184001454	dimer interface; other site
707184001455	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
707184001456	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
707184001457	dimerization interface 3.5A [polypeptide binding]; other site
707184001458	active site
707184001459	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
707184001460	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
707184001461	active site
707184001462	motif I; other site
707184001463	motif II; other site
707184001464	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
707184001465	PAS domain; Region: PAS; smart00091
707184001466	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
707184001467	dimer interface [polypeptide binding]; other site
707184001468	phosphorylation site [posttranslational modification]
707184001469	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707184001470	ATP binding site [chemical binding]; other site
707184001471	Mg2+ binding site [ion binding]; other site
707184001472	G-X-G motif; other site
707184001473	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
707184001474	Response regulator receiver domain; Region: Response_reg; pfam00072
707184001475	active site
707184001476	phosphorylation site [posttranslational modification]
707184001477	intermolecular recognition site; other site
707184001478	dimerization interface [polypeptide binding]; other site
707184001479	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184001480	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
707184001481	Walker A motif; other site
707184001482	ATP binding site [chemical binding]; other site
707184001483	Walker B motif; other site
707184001484	arginine finger; other site
707184001485	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
707184001486	Recombination protein O N terminal; Region: RecO_N; pfam11967
707184001487	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecO; COG1381
707184001488	Recombination protein O C terminal; Region: RecO_C; pfam02565
707184001489	potential protein location (hypothetical protein E150_02490 [Chlamydia trachomatis E/150]) that overlaps RNA (tRNA-L)
707184001490	Uncharacterized conserved protein [Function unknown]; Region: COG1723
707184001491	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
707184001492	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
707184001493	putative tRNA-binding site [nucleotide binding]; other site
707184001494	B3/4 domain; Region: B3_4; pfam03483
707184001495	tRNA synthetase B5 domain; Region: B5; smart00874
707184001496	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
707184001497	dimer interface [polypeptide binding]; other site
707184001498	motif 1; other site
707184001499	motif 3; other site
707184001500	motif 2; other site
707184001501	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
707184001502	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
707184001503	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
707184001504	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
707184001505	DNA binding site [nucleotide binding]
707184001506	active site
707184001507	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
707184001508	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707184001509	dimer interface [polypeptide binding]; other site
707184001510	conserved gate region; other site
707184001511	putative PBP binding loops; other site
707184001512	ABC-ATPase subunit interface; other site
707184001513	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
707184001514	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
707184001515	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
707184001516	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
707184001517	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
707184001518	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
707184001519	putative active site [active]
707184001520	putative metal binding site [ion binding]; other site
707184001521	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707184001522	binding surface
707184001523	TPR motif; other site
707184001524	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
707184001525	Protoheme ferro-lyase (ferrochelatase) [Coenzyme metabolism]; Region: HemH; COG0276
707184001526	C-terminal domain interface [polypeptide binding]; other site
707184001527	active site
707184001528	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
707184001529	active site
707184001530	N-terminal domain interface [polypeptide binding]; other site
707184001531	ABC-type amino acid transport/signal transduction systems, periplasmic component/domain [Amino acid transport and metabolism / Signal transduction mechanisms]; Region: HisJ; COG0834
707184001532	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
707184001533	substrate binding pocket [chemical binding]; other site
707184001534	membrane-bound complex binding site; other site
707184001535	hinge residues; other site
707184001536	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
707184001537	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707184001538	S-adenosylmethionine binding site [chemical binding]; other site
707184001539	Predicted phosphohydrolase [General function prediction only]; Region: COG1768
707184001540	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
707184001541	ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Region: GlgC; COG0448
707184001542	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
707184001543	ligand binding site; other site
707184001544	oligomer interface; other site
707184001545	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
707184001546	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
707184001547	N-terminal domain interface [polypeptide binding]; other site
707184001548	sulfate 1 binding site; other site
707184001549	transcription termination factor Rho; Region: rho; TIGR00767
707184001550	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
707184001551	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
707184001552	RNA binding site [nucleotide binding]; other site
707184001553	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
707184001554	multimer interface [polypeptide binding]; other site
707184001555	Walker A motif; other site
707184001556	ATP binding site [chemical binding]; other site
707184001557	Walker B motif; other site
707184001558	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
707184001559	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
707184001560	CoA-binding site [chemical binding]; other site
707184001561	ATP-binding [chemical binding]; other site
707184001562	DNA polymerase I; Provisional; Region: PRK05755
707184001563	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
707184001564	active site
707184001565	metal binding site 1 [ion binding]; metal-binding site
707184001566	putative 5' ssDNA interaction site; other site
707184001567	metal binding site 3; metal-binding site
707184001568	metal binding site 2 [ion binding]; metal-binding site
707184001569	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
707184001570	putative DNA binding site [nucleotide binding]; other site
707184001571	putative metal binding site [ion binding]; other site
707184001572	3'-5' exonuclease; Region: 35EXOc; smart00474
707184001573	active site
707184001574	substrate binding site [chemical binding]; other site
707184001575	catalytic site [active]
707184001576	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
707184001577	active site
707184001578	DNA binding site [nucleotide binding]
707184001579	catalytic site [active]
707184001580	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
707184001581	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
707184001582	tandem repeat interface [polypeptide binding]; other site
707184001583	oligomer interface [polypeptide binding]; other site
707184001584	active site residues [active]
707184001585	TLC ATP/ADP transporter; Region: TLC; pfam03219
707184001586	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
707184001587	replicative DNA helicase; Provisional; Region: PRK06321
707184001588	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
707184001589	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
707184001590	Walker A motif; other site
707184001591	ATP binding site [chemical binding]; other site
707184001592	Walker B motif; other site
707184001593	DNA binding loops [nucleotide binding]
707184001594	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
707184001595	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
707184001596	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
707184001597	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
707184001598	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
707184001599	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
707184001600	active site
707184001601	multimer interface [polypeptide binding]; other site
707184001602	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
707184001603	RuvA N terminal domain; Region: RuvA_N; pfam01330
707184001604	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
707184001605	active site
707184001606	putative DNA-binding cleft [nucleotide binding]; other site
707184001607	dimer interface [polypeptide binding]; other site
707184001608	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
707184001609	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
707184001610	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
707184001611	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
707184001612	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
707184001613	DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; Region: rpoA; TIGR02027
707184001614	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
707184001615	alphaNTD - beta interaction site [polypeptide binding]; other site
707184001616	alphaNTD homodimer interface [polypeptide binding]; other site
707184001617	alphaNTD - beta' interaction site [polypeptide binding]; other site
707184001618	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
707184001619	30S ribosomal protein S11; Validated; Region: PRK05309
707184001620	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
707184001621	30S ribosomal protein S13; Region: bact_S13; TIGR03631
707184001622	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
707184001623	SecY translocase; Region: SecY; pfam00344
707184001624	ribosomal protein L15, bacterial/organelle; Region: rplO_bact; TIGR01071
707184001625	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
707184001626	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
707184001627	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
707184001628	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
707184001629	5S rRNA interface [nucleotide binding]; other site
707184001630	23S rRNA interface [nucleotide binding]; other site
707184001631	L5 interface [polypeptide binding]; other site
707184001632	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
707184001633	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
707184001634	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
707184001635	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
707184001636	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
707184001637	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
707184001638	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
707184001639	Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Region: RplX; COG0198
707184001640	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
707184001641	RNA binding site [nucleotide binding]; other site
707184001642	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
707184001643	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
707184001644	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
707184001645	23S rRNA interface [nucleotide binding]; other site
707184001646	putative translocon interaction site; other site
707184001647	signal recognition particle (SRP54) interaction site; other site
707184001648	L23 interface [polypeptide binding]; other site
707184001649	trigger factor interaction site; other site
707184001650	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
707184001651	23S rRNA interface [nucleotide binding]; other site
707184001652	5S rRNA interface [nucleotide binding]; other site
707184001653	putative antibiotic binding site [chemical binding]; other site
707184001654	L25 interface [polypeptide binding]; other site
707184001655	L27 interface [polypeptide binding]; other site
707184001656	ribosomal protein S3, bacterial type; Region: rpsC_bact; TIGR01009
707184001657	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
707184001658	G-X-X-G motif; other site
707184001659	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
707184001660	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
707184001661	putative translocon binding site; other site
707184001662	protein-rRNA interface [nucleotide binding]; other site
707184001663	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
707184001664	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
707184001665	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
707184001666	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
707184001667	Ribosomal protein L23 [Translation, ribosomal structure and biogenesis]; Region: RplW; COG0089
707184001668	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
707184001669	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
707184001670	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
707184001671	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
707184001672	putative active site [active]
707184001673	substrate binding site [chemical binding]; other site
707184001674	putative cosubstrate binding site; other site
707184001675	catalytic site [active]
707184001676	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
707184001677	substrate binding site [chemical binding]; other site
707184001678	Acyl-[acyl carrier protein]; Region: LpxA; COG1043
707184001679	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
707184001680	active site
707184001681	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
707184001682	UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell envelope biogenesis, outer membrane]; Region: LpxC; COG0774
707184001683	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
707184001684	Apolipoprotein N-acyltransferase [Cell envelope biogenesis, outer membrane]; Region: Lnt; COG0815
707184001685	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
707184001686	putative active site [active]
707184001687	catalytic triad [active]
707184001688	putative dimer interface [polypeptide binding]; other site
707184001689	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
707184001690	DNA polymerase III subunit epsilon; Validated; Region: PRK06310
707184001691	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
707184001692	active site
707184001693	catalytic site [active]
707184001694	substrate binding site [chemical binding]; other site
707184001695	Protein of unknown function (DUF3820); Region: DUF3820; cl01411
707184001696	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; pfam02367
707184001697	Protein of unknown function (DUF2709); Region: DUF2709; pfam10915
707184001698	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
707184001699	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
707184001700	catalytic residues [active]
707184001701	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
707184001702	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
707184001703	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
707184001704	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
707184001705	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
707184001706	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
707184001707	dimer interface [polypeptide binding]; other site
707184001708	anticodon binding site; other site
707184001709	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
707184001710	homodimer interface [polypeptide binding]; other site
707184001711	motif 1; other site
707184001712	active site
707184001713	motif 2; other site
707184001714	GAD domain; Region: GAD; pfam02938
707184001715	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
707184001716	active site
707184001717	motif 3; other site
707184001718	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
707184001719	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
707184001720	dimer interface [polypeptide binding]; other site
707184001721	motif 1; other site
707184001722	active site
707184001723	motif 2; other site
707184001724	motif 3; other site
707184001725	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
707184001726	anticodon binding site; other site
707184001727	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
707184001728	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707184001729	putative substrate translocation pore; other site
707184001730	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707184001731	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
707184001732	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
707184001733	active site
707184001734	PHP Thumb interface [polypeptide binding]; other site
707184001735	metal binding site [ion binding]; metal-binding site
707184001736	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
707184001737	generic binding surface I; other site
707184001738	generic binding surface II; other site
707184001739	TPR repeat; Region: TPR_11; pfam13414
707184001740	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707184001741	binding surface
707184001742	TPR motif; other site
707184001743	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
707184001744	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
707184001745	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
707184001746	Mg2+ binding site [ion binding]; other site
707184001747	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
707184001748	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
707184001749	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
707184001750	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707184001751	S-adenosylmethionine binding site [chemical binding]; other site
707184001752	branched-chain amino acid uptake carrier; Region: livcs; TIGR00796
707184001753	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
707184001754	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707184001755	ATP binding site [chemical binding]; other site
707184001756	putative Mg++ binding site [ion binding]; other site
707184001757	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707184001758	ATP-binding site [chemical binding]; other site
707184001759	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
707184001760	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
707184001761	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
707184001762	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
707184001763	lipoate synthase; Region: lipA; TIGR00510
707184001764	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
707184001765	FeS/SAM binding site; other site
707184001766	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
707184001767	type III secretion system protein; Validated; Region: PRK06328
707184001768	Flagellar assembly protein FliH; Region: FliH; pfam02108
707184001769	type III secretion system protein; Reviewed; Region: PRK09617
707184001770	Type III secretory pathway, component EscS [Intracellular trafficking and secretion]; Region: EscS; COG4794
707184001771	Type III secretory pathway, component EscT [Intracellular trafficking and secretion]; Region: EscT; COG4791
707184001772	Protein of unknown function (DUF1494); Region: DUF1494; pfam07379
707184001773	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
707184001774	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
707184001775	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
707184001776	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
707184001777	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
707184001778	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
707184001779	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
707184001780	Walker A motif; other site
707184001781	ATP binding site [chemical binding]; other site
707184001782	Walker B motif; other site
707184001783	Type II secretory pathway, component PulD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulD; COG1450
707184001784	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
707184001785	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
707184001786	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
707184001787	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
707184001788	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
707184001789	active site
707184001790	DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair]; Region: MutL; COG0323
707184001791	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707184001792	ATP binding site [chemical binding]; other site
707184001793	Mg2+ binding site [ion binding]; other site
707184001794	G-X-G motif; other site
707184001795	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
707184001796	ATP binding site [chemical binding]; other site
707184001797	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
707184001798	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
707184001799	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707184001800	binding surface
707184001801	TPR motif; other site
707184001802	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
707184001803	EamA-like transporter family; Region: EamA; pfam00892
707184001804	EamA-like transporter family; Region: EamA; pfam00892
707184001805	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
707184001806	The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information...; Region: TGS; cd01616
707184001807	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
707184001808	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
707184001809	active site
707184001810	dimer interface [polypeptide binding]; other site
707184001811	motif 1; other site
707184001812	motif 2; other site
707184001813	motif 3; other site
707184001814	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
707184001815	anticodon binding site; other site
707184001816	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
707184001817	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
707184001818	Uncharacterized protein family (UPF0137); Region: UPF0137; pfam03677
707184001819	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
707184001820	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
707184001821	active site
707184001822	HIGH motif; other site
707184001823	dimer interface [polypeptide binding]; other site
707184001824	KMSKS motif; other site
707184001825	excinuclease ABC subunit B; Provisional; Region: PRK05298
707184001826	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707184001827	ATP binding site [chemical binding]; other site
707184001828	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707184001829	nucleotide binding region [chemical binding]; other site
707184001830	ATP-binding site [chemical binding]; other site
707184001831	Ultra-violet resistance protein B; Region: UvrB; pfam12344
707184001832	enolase; Provisional; Region: eno; PRK00077
707184001833	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
707184001834	dimer interface [polypeptide binding]; other site
707184001835	metal binding site [ion binding]; metal-binding site
707184001836	substrate binding pocket [chemical binding]; other site
707184001837	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
707184001838	HAMP domain; Region: HAMP; pfam00672
707184001839	dimerization interface [polypeptide binding]; other site
707184001840	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
707184001841	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
707184001842	Sigma factor PP2C-like phosphatases; Region: PP2C_SIG; smart00331
707184001843	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK08640
707184001844	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
707184001845	potential frameshift: common BLAST hit: gi|237803021|ref|YP_002888215.1| succinate dehydrogenase flavoprotein subunit
707184001846	Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, transmembrane subunits; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol, while QFR catalyzes the reverse reaction. SQR; Region: SQR_QFR_TM; cl00881
707184001847	Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, transmembrane subunits; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol, while QFR catalyzes the reverse reaction. SQR; Region: SQR_QFR_TM; cl00881
707184001848	proximal heme binding site [chemical binding]; other site
707184001849	Iron-sulfur protein interface; other site
707184001850	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
707184001851	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
707184001852	active site
707184001853	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
707184001854	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
707184001855	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
707184001856	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
707184001857	DsbD alpha interface [polypeptide binding]; other site
707184001858	catalytic residues [active]
707184001859	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
707184001860	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
707184001861	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
707184001862	translocation protein TolB; Provisional; Region: tolB; PRK01029
707184001863	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
707184001864	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
707184001865	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
707184001866	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
707184001867	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
707184001868	ligand binding site [chemical binding]; other site
707184001869	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
707184001870	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
707184001871	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
707184001872	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
707184001873	dimer interface [polypeptide binding]; other site
707184001874	decamer (pentamer of dimers) interface [polypeptide binding]; other site
707184001875	catalytic triad [active]
707184001876	peroxidatic and resolving cysteines [active]
707184001877	Chaperonin GroEL (HSP60 family) [Posttranslational modification, protein turnover, chaperones]; Region: GroL; COG0459
707184001878	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
707184001879	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3876
707184001880	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
707184001881	active site
707184001882	dimerization interface [polypeptide binding]; other site
707184001883	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
707184001884	ligand binding site [chemical binding]; other site
707184001885	active site
707184001886	UGI interface [polypeptide binding]; other site
707184001887	catalytic site [active]
707184001888	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
707184001889	Part of AAA domain; Region: AAA_19; pfam13245
707184001890	Family description; Region: UvrD_C_2; pfam13538
707184001891	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog [Transcription]; Region: RpoN; COG1508
707184001892	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
707184001893	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
707184001894	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
707184001895	Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C [Coenzyme metabolism]; Region: COG5424
707184001896	GTP and metal dependent enzyme involved F420 coenzyme biosynthesis (catalyzes addition of two l-glutamates to F420 precursor) [Coenzyme transport and metabolism]; Region: COG1478
707184001897	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; cl00644
707184001898	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
707184001899	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
707184001900	folate binding site [chemical binding]; other site
707184001901	NADP+ binding site [chemical binding]; other site
707184001902	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
707184001903	catalytic center binding site [active]
707184001904	ATP binding site [chemical binding]; other site
707184001905	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
707184001906	dihydropteroate synthase; Region: DHPS; TIGR01496
707184001907	substrate binding pocket [chemical binding]; other site
707184001908	dimer interface [polypeptide binding]; other site
707184001909	inhibitor binding site; inhibition site
707184001910	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
707184001911	homooctamer interface [polypeptide binding]; other site
707184001912	active site
707184001913	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
707184001914	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
707184001915	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
707184001916	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
707184001917	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
707184001918	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
707184001919	DNA binding residues [nucleotide binding]
707184001920	Uncharacterized protein family (UPF0242); Region: UPF0242; pfam06785
707184001921	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
707184001922	Effector from type III secretion system; Region: Effector_1; pfam04518
707184001923	Effector from type III secretion system; Region: Effector_1; pfam04518
707184001924	Effector from type III secretion system; Region: Effector_1; pfam04518
707184001925	Exodeoxyribonuclease V, gamma subunit; Region: Exonuc_V_gamma; pfam04257
707184001926	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
707184001927	MviN-like protein; Region: MVIN; pfam03023
707184001928	endonuclease IV; Provisional; Region: PRK01060
707184001929	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
707184001930	AP (apurinic/apyrimidinic) site pocket; other site
707184001931	DNA interaction; other site
707184001932	Metal-binding active site; metal-binding site
707184001933	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
707184001934	ribosomal protein S4, bacterial/organelle type; Region: rpsD_bact; TIGR01017
707184001935	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707184001936	RNA binding surface [nucleotide binding]; other site
707184001937	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
707184001938	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
707184001939	active site residue [active]
707184001940	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
707184001941	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
707184001942	substrate binding pocket [chemical binding]; other site
707184001943	chain length determination region; other site
707184001944	substrate-Mg2+ binding site; other site
707184001945	catalytic residues [active]
707184001946	aspartate-rich region 1; other site
707184001947	active site lid residues [active]
707184001948	aspartate-rich region 2; other site
707184001949	Putative glucose-1-phosphate thymidylyltransferase, C-terminal Left-handed parallel beta-Helix (LbH) domain: Proteins in this family show simlarity to glucose-1-phosphate adenylyltransferases in that they contain N-terminal catalytic domains that...; Region: LbH_G1P_TT_C_like; cd05636
707184001950	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
707184001951	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
707184001952	DNA binding site [nucleotide binding]
707184001953	Predicted alternative thymidylate synthase [Nucleotide transport and metabolism]; Region: THY1; COG1351
707184001954	Thymidylate synthase complementing protein; Region: Thy1; cl03630
707184001955	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
707184001956	dimer interface [polypeptide binding]; other site
707184001957	active site
707184001958	aspartate-rich active site metal binding site; other site
707184001959	allosteric magnesium binding site [ion binding]; other site
707184001960	Schiff base residues; other site
707184001961	NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit; Region: nqrA; TIGR01936
707184001962	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
707184001963	lipoyl-biotinyl attachment site [posttranslational modification]; other site
707184001964	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
707184001965	Putative bacteriophage terminase small subunit; Region: Phage_term_sma; pfam07141
707184001966	transcript cleavage factor/unknown domain fusion protein; Validated; Region: PRK06330
707184001967	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
707184001968	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
707184001969	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
707184001970	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
707184001971	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707184001972	homodimer interface [polypeptide binding]; other site
707184001973	catalytic residue [active]
707184001974	rod shape-determining protein MreC; Provisional; Region: PRK14872
707184001975	rod shape-determining protein MreC; Region: MreC; pfam04085
707184001976	exodeoxyribonuclease V, beta subunit; Region: recB; TIGR00609
707184001977	Part of AAA domain; Region: AAA_19; pfam13245
707184001978	Family description; Region: UvrD_C_2; pfam13538
707184001979	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
707184001980	Major Facilitator Superfamily; Region: MFS_1; pfam07690
707184001981	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707184001982	putative substrate translocation pore; other site
707184001983	DNA topoisomerase I/SWI domain fusion protein; Validated; Region: PRK06319
707184001984	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
707184001985	active site
707184001986	interdomain interaction site; other site
707184001987	putative metal-binding site [ion binding]; other site
707184001988	nucleotide binding site [chemical binding]; other site
707184001989	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
707184001990	domain I; other site
707184001991	DNA binding groove [nucleotide binding]
707184001992	phosphate binding site [ion binding]; other site
707184001993	domain II; other site
707184001994	domain III; other site
707184001995	nucleotide binding site [chemical binding]; other site
707184001996	catalytic site [active]
707184001997	domain IV; other site
707184001998	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
707184001999	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
707184002000	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
707184002001	SWI complex, BAF60b domains; Region: SWIB; smart00151
707184002002	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
707184002003	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
707184002004	FMN binding site [chemical binding]; other site
707184002005	active site
707184002006	catalytic residues [active]
707184002007	substrate binding site [chemical binding]; other site
707184002008	Predicted integral membrane protein [Function unknown]; Region: COG0762
707184002009	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
707184002010	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
707184002011	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
707184002012	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
707184002013	recombinase A; Provisional; Region: recA; PRK09354
707184002014	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
707184002015	hexamer interface [polypeptide binding]; other site
707184002016	Walker A motif; other site
707184002017	ATP binding site [chemical binding]; other site
707184002018	Walker B motif; other site
707184002019	Protein of unknown function (DUF1347); Region: DUF1347; pfam07079
707184002020	exodeoxyribonuclease V, alpha subunit; Region: recD; TIGR01447
707184002021	AAA domain; Region: AAA_30; pfam13604
707184002022	Family description; Region: UvrD_C_2; pfam13538
707184002023	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
707184002024	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
707184002025	Walker A/P-loop; other site
707184002026	ATP binding site [chemical binding]; other site
707184002027	Q-loop/lid; other site
707184002028	ABC transporter signature motif; other site
707184002029	Walker B; other site
707184002030	D-loop; other site
707184002031	H-loop/switch region; other site
707184002032	Protein of unknown function (DUF1137); Region: DUF1137; pfam06587
707184002033	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
707184002034	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
707184002035	potential protein location (hypothetical protein E150_03485 [Chlamydia trachomatis E/150]) that overlaps RNA (tRNA-R)
707184002036	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
707184002037	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707184002038	RNA binding surface [nucleotide binding]; other site
707184002039	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
707184002040	active site
707184002041	hypothetical protein; Provisional; Region: PRK01064
707184002042	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
707184002043	DNA topoisomerase IV subunit A; Provisional; Region: PRK09630
707184002044	DNA Topoisomerase IV; Region: TOP4c; smart00434
707184002045	CAP-like domain; other site
707184002046	active site
707184002047	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
707184002048	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707184002049	ATP binding site [chemical binding]; other site
707184002050	Mg2+ binding site [ion binding]; other site
707184002051	G-X-G motif; other site
707184002052	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of type II DNA topoisomerases (Topo II) and DNA mismatch repair (MutL/MLH1/PMS2) proteins. This transducer domain is homologous to the second...; Region: TopoII_MutL_Trans; cl02783
707184002053	ATP binding site [chemical binding]; other site
707184002054	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
707184002055	active site
707184002056	putative metal-binding site [ion binding]; other site
707184002057	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
707184002058	glutamyl-tRNA reductase; Validated; Region: hemA; PRK00676
707184002059	Glutamyl-tRNAGlu reductase, N-terminal domain; Region: GlutR_N; pfam05201
707184002060	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
707184002061	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
707184002062	phosphopeptide binding site; other site
707184002063	MARCKS family; Region: MARCKS; pfam02063
707184002064	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
707184002065	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
707184002066	phosphopeptide binding site; other site
707184002067	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
707184002068	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
707184002069	binding surface
707184002070	Tetratricopeptide repeat; Region: TPR_16; pfam13432
707184002071	TPR motif; other site
707184002072	type III secretion system ATPase; Provisional; Region: PRK06315
707184002073	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707184002074	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
707184002075	Walker A motif/ATP binding site; other site
707184002076	Walker B motif; other site
707184002077	type III secretion system protein; Validated; Region: PRK05933
707184002078	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
707184002079	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
707184002080	Catalytic domain of Protein Kinases; Region: PKc; cd00180
707184002081	active site
707184002082	ATP binding site [chemical binding]; other site
707184002083	substrate binding site [chemical binding]; other site
707184002084	activation loop (A-loop); other site
707184002085	Type II secretory pathway, component PulD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulD; COG1450
707184002086	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
707184002087	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
707184002088	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
707184002089	Arginine kinase [Amino acid transport and metabolism]; Region: COG3869
707184002090	Phosphagen (guanidino) kinases; Region: phosphagen_kinases; cl02823
707184002091	ADP binding site [chemical binding]; other site
707184002092	phosphagen binding site; other site
707184002093	substrate specificity loop; other site
707184002094	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
707184002095	UvrB/uvrC motif; Region: UVR; pfam02151
707184002096	ribosome recycling factor; Reviewed; Region: frr; PRK00083
707184002097	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
707184002098	hinge region; other site
707184002099	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
707184002100	putative nucleotide binding site [chemical binding]; other site
707184002101	uridine monophosphate binding site [chemical binding]; other site
707184002102	homohexameric interface [polypeptide binding]; other site
707184002103	Translation elongation factor Ts [Translation, ribosomal structure and biogenesis]; Region: Tsf; COG0264
707184002104	Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; Region: UBA; cl00153
707184002105	Elongation factor TS; Region: EF_TS; pfam00889
707184002106	Elongation factor TS; Region: EF_TS; pfam00889
707184002107	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
707184002108	rRNA interaction site [nucleotide binding]; other site
707184002109	S8 interaction site; other site
707184002110	putative laminin-1 binding site; other site
707184002111	Chlamydia major outer membrane protein; Region: Chlam_OMP; pfam01308
707184002112	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
707184002113	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
707184002114	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
707184002115	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
707184002116	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707184002117	TPR motif; other site
707184002118	Tetratricopeptide repeat; Region: TPR_16; pfam13432
707184002119	binding surface
707184002120	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707184002121	binding surface
707184002122	TPR motif; other site
707184002123	TPR repeat; Region: TPR_11; pfam13414
707184002124	TPR repeat; Region: TPR_11; pfam13414
707184002125	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707184002126	binding surface
707184002127	TPR motif; other site
707184002128	TPR repeat; Region: TPR_11; pfam13414
707184002129	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
707184002130	putative ABC transporter; Region: ycf24; CHL00085
707184002131	FeS assembly ATPase SufC; Region: sufC; TIGR01978
707184002132	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
707184002133	Walker A/P-loop; other site
707184002134	ATP binding site [chemical binding]; other site
707184002135	Q-loop/lid; other site
707184002136	ABC transporter signature motif; other site
707184002137	Walker B; other site
707184002138	D-loop; other site
707184002139	H-loop/switch region; other site
707184002140	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
707184002141	FeS assembly protein SufD; Region: sufD; TIGR01981
707184002142	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
707184002143	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
707184002144	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707184002145	catalytic residue [active]
707184002146	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
707184002147	ParB-like nuclease domain; Region: ParBc; pfam02195
707184002148	KorB domain; Region: KorB; pfam08535
707184002149	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707184002150	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
707184002151	Walker A/P-loop; other site
707184002152	ATP binding site [chemical binding]; other site
707184002153	Q-loop/lid; other site
707184002154	ABC transporter signature motif; other site
707184002155	Walker B; other site
707184002156	D-loop; other site
707184002157	H-loop/switch region; other site
707184002158	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
707184002159	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
707184002160	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707184002161	Walker A/P-loop; other site
707184002162	ATP binding site [chemical binding]; other site
707184002163	Q-loop/lid; other site
707184002164	ABC transporter signature motif; other site
707184002165	Walker B; other site
707184002166	D-loop; other site
707184002167	H-loop/switch region; other site
707184002168	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
707184002169	Protein of unknown function DUF47; Region: PhoU_div; pfam01865
707184002170	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
707184002171	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
707184002172	Phosphoglycerate kinase; Region: PGK; pfam00162
707184002173	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
707184002174	substrate binding site [chemical binding]; other site
707184002175	hinge regions; other site
707184002176	ADP binding site [chemical binding]; other site
707184002177	catalytic site [active]
707184002178	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
707184002179	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
707184002180	minor groove reading motif; other site
707184002181	helix-hairpin-helix signature motif; other site
707184002182	substrate binding pocket [chemical binding]; other site
707184002183	active site
707184002184	Predicted GTPase [General function prediction only]; Region: ThdF; COG0486
707184002185	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
707184002186	trmE is a tRNA modification GTPase; Region: trmE; cd04164
707184002187	G1 box; other site
707184002188	GTP/Mg2+ binding site [chemical binding]; other site
707184002189	Switch I region; other site
707184002190	G2 box; other site
707184002191	Switch II region; other site
707184002192	G3 box; other site
707184002193	G4 box; other site
707184002194	G5 box; other site
707184002195	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
707184002196	phosphatidylserine decarboxylase; Provisional; Region: PRK00723
707184002197	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707184002198	binding surface
707184002199	TPR motif; other site
707184002200	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12899
707184002201	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
707184002202	ATP binding site [chemical binding]; other site
707184002203	putative Mg++ binding site [ion binding]; other site
707184002204	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
707184002205	Predicted GTPases [General function prediction only]; Region: COG1160
707184002206	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
707184002207	G1 box; other site
707184002208	GTP/Mg2+ binding site [chemical binding]; other site
707184002209	Switch I region; other site
707184002210	G2 box; other site
707184002211	Switch II region; other site
707184002212	G3 box; other site
707184002213	G4 box; other site
707184002214	G5 box; other site
707184002215	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
707184002216	G1 box; other site
707184002217	GTP/Mg2+ binding site [chemical binding]; other site
707184002218	Switch I region; other site
707184002219	G2 box; other site
707184002220	G3 box; other site
707184002221	Switch II region; other site
707184002222	G4 box; other site
707184002223	G5 box; other site
707184002224	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
707184002225	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
707184002226	active site
707184002227	NTP binding site [chemical binding]; other site
707184002228	metal binding triad [ion binding]; metal-binding site
707184002229	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
707184002230	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
707184002231	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
707184002232	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184002233	Walker A motif; other site
707184002234	ATP binding site [chemical binding]; other site
707184002235	Walker B motif; other site
707184002236	arginine finger; other site
707184002237	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
707184002238	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
707184002239	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
707184002240	oligomer interface [polypeptide binding]; other site
707184002241	active site residues [active]
707184002242	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) [Posttranslational modification, protein turnover, chaperones]; Region: Tig; COG0544
707184002243	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
707184002244	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
707184002245	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
707184002246	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707184002247	ATP binding site [chemical binding]; other site
707184002248	putative Mg++ binding site [ion binding]; other site
707184002249	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707184002250	nucleotide binding region [chemical binding]; other site
707184002251	ATP-binding site [chemical binding]; other site
707184002252	rod shape-determining protein MreB; Provisional; Region: PRK13927
707184002253	MreB and similar proteins; Region: MreB_like; cd10225
707184002254	nucleotide binding site [chemical binding]; other site
707184002255	Mg binding site [ion binding]; other site
707184002256	putative protofilament interaction site [polypeptide binding]; other site
707184002257	RodZ interaction site [polypeptide binding]; other site
707184002258	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819
707184002259	active site
707184002260	substrate-binding site [chemical binding]; other site
707184002261	metal-binding site [ion binding]
707184002262	GTP binding site [chemical binding]; other site
707184002263	Effector from type III secretion system; Region: Effector_1; pfam04518
707184002264	Effector from type III secretion system; Region: Effector_1; pfam04518
707184002265	Chlamydia major outer membrane protein; Region: Chlam_OMP; pfam01308
707184002266	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
707184002267	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
707184002268	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
707184002269	UDP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Region: COG4284
707184002270	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
707184002271	active site
707184002272	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
707184002273	type III secretion system ATPase; Validated; Region: PRK05922
707184002274	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707184002275	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
707184002276	Walker A motif; other site
707184002277	ATP binding site [chemical binding]; other site
707184002278	Walker B motif; other site
707184002279	type III secretion system protein; Validated; Region: PRK05934
707184002280	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
707184002281	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cl00528
707184002282	active site
707184002283	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
707184002284	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
707184002285	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707184002286	catalytic residue [active]
707184002287	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
707184002288	catalytic core [active]
707184002289	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
707184002290	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707184002291	RNA binding surface [nucleotide binding]; other site
707184002292	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
707184002293	active site
707184002294	biotin--protein ligase; Provisional; Region: PRK05935
707184002295	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
707184002296	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
707184002297	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
707184002298	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
707184002299	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
707184002300	motif II; other site
707184002301	CCC1-related protein family; Region: CCC1_like_1; cd02437
707184002302	seryl-tRNA synthetase; Provisional; Region: PRK05431
707184002303	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
707184002304	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
707184002305	dimer interface [polypeptide binding]; other site
707184002306	active site
707184002307	motif 1; other site
707184002308	motif 2; other site
707184002309	motif 3; other site
707184002310	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
707184002311	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
707184002312	catalytic motif [active]
707184002313	Zn binding site [ion binding]; other site
707184002314	RibD C-terminal domain; Region: RibD_C; pfam01872
707184002315	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
707184002316	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
707184002317	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
707184002318	dimerization interface [polypeptide binding]; other site
707184002319	active site
707184002320	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
707184002321	homopentamer interface [polypeptide binding]; other site
707184002322	active site
707184002323	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
707184002324	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
707184002325	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
707184002326	substrate binding site [chemical binding]; other site
707184002327	Proteins containing SET domain [General function prediction only]; Region: COG2940
707184002328	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; Region: SET; smart00317
707184002329	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
707184002330	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
707184002331	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
707184002332	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
707184002333	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
707184002334	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF [Energy production and conversion]; Region: NqrF; COG2871
707184002335	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
707184002336	catalytic loop [active]
707184002337	iron binding site [ion binding]; other site
707184002338	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
707184002339	FAD binding pocket [chemical binding]; other site
707184002340	FAD binding motif [chemical binding]; other site
707184002341	phosphate binding motif [ion binding]; other site
707184002342	beta-alpha-beta structure motif; other site
707184002343	NAD binding pocket [chemical binding]; other site
707184002344	preprotein translocase, YajC subunit; Region: yajC; TIGR00739
707184002345	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
707184002346	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707184002347	S-adenosylmethionine binding site [chemical binding]; other site
707184002348	Histone H1-like protein Hc1; Region: Hc1; pfam07432
707184002349	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707184002350	binding surface
707184002351	TPR motif; other site
707184002352	Tetratricopeptide repeat; Region: TPR_12; pfam13424
707184002353	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
707184002354	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
707184002355	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
707184002356	HemN C-terminal domain; Region: HemN_C; pfam06969
707184002357	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
707184002358	substrate binding site [chemical binding]; other site
707184002359	active site
707184002360	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
707184002361	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
707184002362	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707184002363	ATP binding site [chemical binding]; other site
707184002364	putative Mg++ binding site [ion binding]; other site
707184002365	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707184002366	nucleotide binding region [chemical binding]; other site
707184002367	ATP-binding site [chemical binding]; other site
707184002368	TRCF domain; Region: TRCF; pfam03461
707184002369	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
707184002370	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
707184002371	motif 1; other site
707184002372	active site
707184002373	motif 2; other site
707184002374	motif 3; other site
707184002375	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
707184002376	DHHA1 domain; Region: DHHA1; pfam02272
707184002377	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
707184002378	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
707184002379	TPP-binding site [chemical binding]; other site
707184002380	dimer interface [polypeptide binding]; other site
707184002381	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
707184002382	PYR/PP interface [polypeptide binding]; other site
707184002383	dimer interface [polypeptide binding]; other site
707184002384	TPP binding site [chemical binding]; other site
707184002385	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707184002386	AMP nucleosidase, putative; Region: AMN-like; TIGR01721
707184002387	elongation factor P; Validated; Region: PRK00529
707184002388	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
707184002389	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
707184002390	RNA binding site [nucleotide binding]; other site
707184002391	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
707184002392	RNA binding site [nucleotide binding]; other site
707184002393	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
707184002394	Bacillus subtilis YydB and related proteins, metallophosphatase domain; Region: MPP_YydB; cd07400
707184002395	putative active site [active]
707184002396	putative metal binding site [ion binding]; other site
707184002397	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
707184002398	active site
707184002399	metal binding site [ion binding]; metal-binding site
707184002400	Chaperonin GroEL (HSP60 family) [Posttranslational modification, protein turnover, chaperones]; Region: GroL; COG0459
707184002401	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
707184002402	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
707184002403	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707184002404	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707184002405	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
707184002406	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
707184002407	Mg++ binding site [ion binding]; other site
707184002408	putative catalytic motif [active]
707184002409	putative substrate binding site [chemical binding]; other site
707184002410	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK00683
707184002411	TrkA-N domain; Region: TrkA_N; pfam02254
707184002412	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707184002413	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707184002414	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
707184002415	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
707184002416	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
707184002417	cell division protein FtsW; Region: ftsW; TIGR02614
707184002418	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
707184002419	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
707184002420	active site
707184002421	homodimer interface [polypeptide binding]; other site
707184002422	bifunctional D-alanyl-alanine synthetase A/UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: PRK14573
707184002423	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
707184002424	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707184002425	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707184002426	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
707184002427	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
707184002428	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
707184002429	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cd02409
707184002430	G-X-X-G motif; other site
707184002431	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
707184002432	anti sigma factor interaction site; other site
707184002433	regulatory phosphorylation site [posttranslational modification]; other site
707184002434	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
707184002435	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
707184002436	hypothetical protein; Provisional; Region: PRK05927
707184002437	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
707184002438	FeS/SAM binding site; other site
707184002439	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
707184002440	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
707184002441	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK06333
707184002442	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
707184002443	dimer interface [polypeptide binding]; other site
707184002444	active site
707184002445	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Ap4A hydrolases are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_human_like; cd03428
707184002446	active site
707184002447	Ap4A binding cleft/pocket [chemical binding]; other site
707184002448	P4 phosphate binding site; other site
707184002449	nudix motif; other site
707184002450	putative P2/P3 phosphate binding site [ion binding]; other site
707184002451	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
707184002452	dimer interface [polypeptide binding]; other site
707184002453	substrate binding site [chemical binding]; other site
707184002454	metal binding sites [ion binding]; metal-binding site
707184002455	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
707184002456	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
707184002457	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
707184002458	NAD binding site [chemical binding]; other site
707184002459	Phe binding site; other site
707184002460	PAP-phosphatase_like domains. PAP-phosphatase is a member of the inositol monophosphatase family, and catalyses the hydrolysis of 3'-phosphoadenosine-5'-phosphate (PAP) to AMP. In Saccharomyces cerevisiae, HAL2 (MET22) is involved in methionine...; Region: PAP_phosphatase; cd01517
707184002461	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
707184002462	active site
707184002463	putative lithium-binding site [ion binding]; other site
707184002464	substrate binding site [chemical binding]; other site
707184002465	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
707184002466	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
707184002467	putative acyl-acceptor binding pocket; other site
707184002468	long chain fatty acid--[acyl-carrier-protein] ligase; Validated; Region: PRK06334
707184002469	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
707184002470	acyl-activating enzyme (AAE) consensus motif; other site
707184002471	AMP binding site [chemical binding]; other site
707184002472	active site
707184002473	CoA binding site [chemical binding]; other site
707184002474	8-amino-7-oxononanoate synthase; Provisional; Region: PRK05937
707184002475	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
707184002476	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707184002477	catalytic residue [active]
707184002478	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
707184002479	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707184002480	ATP binding site [chemical binding]; other site
707184002481	putative Mg++ binding site [ion binding]; other site
707184002482	helicase superfamily c-terminal domain; Region: HELICc; smart00490
707184002483	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
707184002484	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
707184002485	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
707184002486	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
707184002487	dimer interface [polypeptide binding]; other site
707184002488	putative anticodon binding site; other site
707184002489	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
707184002490	motif 1; other site
707184002491	dimer interface [polypeptide binding]; other site
707184002492	active site
707184002493	motif 2; other site
707184002494	motif 3; other site
707184002495	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
707184002496	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
707184002497	active site
707184002498	HIGH motif; other site
707184002499	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
707184002500	KMSKS motif; other site
707184002501	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
707184002502	tRNA binding surface [nucleotide binding]; other site
707184002503	anticodon binding site; other site
707184002504	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
707184002505	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
707184002506	ribonuclease P; Reviewed; Region: rnpA; PRK00730
707184002507	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
707184002508	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
707184002509	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
707184002510	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
707184002511	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
707184002512	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
707184002513	GIY-YIG motif/motif A; other site
707184002514	active site
707184002515	catalytic site [active]
707184002516	putative DNA binding site [nucleotide binding]; other site
707184002517	metal binding site [ion binding]; metal-binding site
707184002518	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
707184002519	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
707184002520	MutS domain I; Region: MutS_I; pfam01624
707184002521	MutS domain II; Region: MutS_II; pfam05188
707184002522	MutS domain III; Region: MutS_III; pfam05192
707184002523	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
707184002524	Walker A/P-loop; other site
707184002525	ATP binding site [chemical binding]; other site
707184002526	Q-loop/lid; other site
707184002527	ABC transporter signature motif; other site
707184002528	Walker B; other site
707184002529	D-loop; other site
707184002530	H-loop/switch region; other site
707184002531	DNA primase; Validated; Region: dnaG; PRK05667
707184002532	CHC2 zinc finger; Region: zf-CHC2; pfam01807
707184002533	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
707184002534	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
707184002535	active site
707184002536	metal binding site [ion binding]; metal-binding site
707184002537	interdomain interaction site; other site
707184002538	glycyl-tRNA synthetase; Provisional; Region: PRK14908
707184002539	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
707184002540	dimer interface [polypeptide binding]; other site
707184002541	motif 1; other site
707184002542	active site
707184002543	motif 2; other site
707184002544	motif 3; other site
707184002545	DALR anticodon binding domain; Region: DALR_1; pfam05746
707184002546	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
707184002547	glycogen synthase; Provisional; Region: glgA; PRK00654
707184002548	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
707184002549	ADP-binding pocket [chemical binding]; other site
707184002550	homodimer interface [polypeptide binding]; other site
707184002551	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
707184002552	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
707184002553	5S rRNA interface [nucleotide binding]; other site
707184002554	CTC domain interface [polypeptide binding]; other site
707184002555	L16 interface [polypeptide binding]; other site
707184002556	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
707184002557	putative active site [active]
707184002558	catalytic residue [active]
707184002559	Ribosomal protein S6 [Translation, ribosomal structure and biogenesis]; Region: RpsF; COG0360
707184002560	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
707184002561	Ribosomal protein L9 [Translation, ribosomal structure and biogenesis]; Region: RplI; COG0359
707184002562	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
707184002563	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
707184002564	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK00650
707184002565	Protein of unknown function (DUF1504); Region: DUF1504; pfam07399
707184002566	Secreted/periplasmic Zn-dependent peptidases, insulinase-like [Posttranslational modification, protein turnover, chaperones]; Region: Ptr; COG1025
707184002567	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
707184002568	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707184002569	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707184002570	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
707184002571	putative acyl-acceptor binding pocket; other site
707184002572	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
707184002573	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
707184002574	homodimer interface [polypeptide binding]; other site
707184002575	oligonucleotide binding site [chemical binding]; other site
707184002576	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
707184002577	putative glycerol-3-phosphate acyltransferase PlsX; Provisional; Region: PRK13846
707184002578	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707184002579	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707184002580	YtxH-like protein; Region: YtxH; cl02079
707184002581	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14314
707184002582	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
707184002583	active site
707184002584	substrate binding site [chemical binding]; other site
707184002585	metal binding site [ion binding]; metal-binding site
707184002586	glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Region: glmS; TIGR01135
707184002587	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
707184002588	glutaminase active site [active]
707184002589	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
707184002590	dimer interface [polypeptide binding]; other site
707184002591	active site
707184002592	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
707184002593	dimer interface [polypeptide binding]; other site
707184002594	active site
707184002595	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; pfam03222
707184002596	aromatic amino acid transport protein; Region: araaP; TIGR00837
707184002597	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; pfam03222
707184002598	aromatic amino acid transport protein; Region: araaP; TIGR00837
707184002599	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
707184002600	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
707184002601	SRP54-type protein, GTPase domain; Region: SRP54; pfam00448
707184002602	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
707184002603	succinyl-CoA synthetase, beta subunit; Region: sucCoAbeta; TIGR01016
707184002604	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
707184002605	CoA-ligase; Region: Ligase_CoA; pfam00549
707184002606	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
707184002607	CoA binding domain; Region: CoA_binding; smart00881
707184002608	CoA-ligase; Region: Ligase_CoA; pfam00549
707184002609	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
707184002610	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
707184002611	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
707184002612	protein binding site [polypeptide binding]; other site
707184002613	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
707184002614	protein binding site [polypeptide binding]; other site
707184002615	Predicted Zn-dependent peptidases, insulinase-like [General function prediction only]; Region: COG1026
707184002616	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
707184002617	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707184002618	Peptidase M16C associated; Region: M16C_assoc; pfam08367
707184002619	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707184002620	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
707184002621	RmuC family; Region: RmuC; pfam02646
707184002622	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
707184002623	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
707184002624	ribonucleotide-diphosphate reductase subunit alpha; Provisional; Region: PRK12365
707184002625	ATP cone domain; Region: ATP-cone; pfam03477
707184002626	ATP cone domain; Region: ATP-cone; pfam03477
707184002627	Class I ribonucleotide reductase; Region: RNR_I; cd01679
707184002628	active site
707184002629	dimer interface [polypeptide binding]; other site
707184002630	catalytic residues [active]
707184002631	effector binding site; other site
707184002632	R2 peptide binding site; other site
707184002633	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
707184002634	dimer interface [polypeptide binding]; other site
707184002635	putative radical transfer pathway; other site
707184002636	diiron center [ion binding]; other site
707184002637	tyrosyl radical; other site
707184002638	Putative methyltransferase; Region: Methyltransf_4; pfam02390
707184002639	Methyltransferase domain; Region: Methyltransf_18; pfam12847
707184002640	Putative rRNA methylase; Region: rRNA_methylase; pfam06962
707184002641	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
707184002642	FAD binding domain; Region: FAD_binding_4; pfam01565
707184002643	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
707184002644	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
707184002645	putative RNA binding site [nucleotide binding]; other site
707184002646	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
707184002647	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
707184002648	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
707184002649	Ribosomal protein L35 [Translation, ribosomal structure and biogenesis]; Region: RpmI; COG0291
707184002650	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
707184002651	23S rRNA binding site [nucleotide binding]; other site
707184002652	L21 binding site [polypeptide binding]; other site
707184002653	L13 binding site [polypeptide binding]; other site
707184002654	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
707184002655	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
707184002656	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
707184002657	motif 1; other site
707184002658	dimer interface [polypeptide binding]; other site
707184002659	active site
707184002660	motif 2; other site
707184002661	motif 3; other site
707184002662	Predicted permeases [General function prediction only]; Region: COG0795
707184002663	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
707184002664	Predicted permeases [General function prediction only]; Region: COG0795
707184002665	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
707184002666	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
707184002667	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
707184002668	Ligand Binding Site [chemical binding]; other site
707184002669	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
707184002670	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707184002671	Walker A motif; other site
707184002672	ATP binding site [chemical binding]; other site
707184002673	Walker B motif; other site
707184002674	arginine finger; other site
707184002675	Peptidase family M41; Region: Peptidase_M41; pfam01434
707184002676	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
707184002677	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
707184002678	RNase E interface [polypeptide binding]; other site
707184002679	trimer interface [polypeptide binding]; other site
707184002680	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
707184002681	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
707184002682	RNase E interface [polypeptide binding]; other site
707184002683	trimer interface [polypeptide binding]; other site
707184002684	active site
707184002685	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
707184002686	putative nucleic acid binding region [nucleotide binding]; other site
707184002687	G-X-X-G motif; other site
707184002688	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
707184002689	RNA binding site [nucleotide binding]; other site
707184002690	domain interface; other site
707184002691	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
707184002692	16S/18S rRNA binding site [nucleotide binding]; other site
707184002693	S13e-L30e interaction site [polypeptide binding]; other site
707184002694	25S rRNA binding site [nucleotide binding]; other site
707184002695	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
707184002696	nucleoside/Zn binding site; other site
707184002697	dimer interface [polypeptide binding]; other site
707184002698	catalytic motif [active]
707184002699	Protein of unknown function (DUF720); Region: DUF720; pfam05302
707184002700	Protein of unknown function (DUF720); Region: DUF720; pfam05302
707184002701	Protein of unknown function (DUF720); Region: DUF720; pfam05302
707184002702	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
707184002703	methionine aminopeptidase; Provisional; Region: PRK12318
707184002704	SEC-C motif; Region: SEC-C; pfam02810
707184002705	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
707184002706	active site
707184002707	MarC family integral membrane protein; Region: MarC; pfam01914
707184002708	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
707184002709	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
707184002710	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707184002711	dimer interface [polypeptide binding]; other site
707184002712	conserved gate region; other site
707184002713	putative PBP binding loops; other site
707184002714	ABC-ATPase subunit interface; other site
707184002715	NMT1/THI5 like; Region: NMT1; pfam09084
707184002716	fumarate hydratase, class II; Region: fumC_II; TIGR00979
707184002717	Class II fumarases; Region: Fumarase_classII; cd01362
707184002718	active site
707184002719	tetramer interface [polypeptide binding]; other site
707184002720	high affinity sulphate transporter 1; Region: sulP; TIGR00815
707184002721	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
707184002722	Sulfate transporter family; Region: Sulfate_transp; pfam00916
707184002723	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
707184002724	Na+/H+ antiporter, NhaD family; Region: NhaD; TIGR00775
707184002725	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
707184002726	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
707184002727	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
707184002728	Interphotoreceptor retinoid-binding protein; serine protease family S41; Region: Peptidase_S41_IRBP; cd07563
707184002729	active site triad [active]
707184002730	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
707184002731	LytB protein; Region: LYTB; pfam02401
707184002732	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
707184002733	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707184002734	binding surface
707184002735	TPR motif; other site
707184002736	potential protein location (hypothetical protein E150_04635 [Chlamydia trachomatis E/150]) that overlaps RNA (tRNA-L)
707184002737	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
707184002738	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
707184002739	active site
707184002740	DNA binding site [nucleotide binding]
707184002741	Int/Topo IB signature motif; other site
707184002742	glycogen branching enzyme; Provisional; Region: PRK05402
707184002743	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
707184002744	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
707184002745	active site
707184002746	catalytic site [active]
707184002747	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
707184002748	Ulp1 protease family, C-terminal catalytic domain; Region: Peptidase_C48; cl17784
707184002749	Ulp1 protease family, C-terminal catalytic domain; Region: Peptidase_C48; cl17784
707184002750	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707184002751	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707184002752	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707184002753	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707184002754	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707184002755	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707184002756	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707184002757	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707184002758	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707184002759	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707184002760	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707184002761	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707184002762	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707184002763	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707184002764	Autotransporter beta-domain; Region: Autotransporter; pfam03797