-- dump date   	20140619_032338
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
707183000001	Uncharacterized conserved protein [Function unknown]; Region: COG2155
707183000002	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit [Translation, ribosomal structure and biogenesis]; Region: GatC; COG0721
707183000003	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
707183000004	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
707183000005	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) [Translation, ribosomal structure and biogenesis]; Region: GatB; COG0064
707183000006	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
707183000007	GatB domain; Region: GatB_Yqey; pfam02637
707183000008	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
707183000009	ribonuclease HIII; Region: rnhC; TIGR00716
707183000010	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
707183000011	RNA/DNA hybrid binding site [nucleotide binding]; other site
707183000012	active site
707183000013	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
707183000014	Helix-turn-helix domain; Region: HTH_25; pfam13413
707183000015	lipid A biosynthesis lauroyl acyltransferase; Provisional; Region: PRK05906
707183000016	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
707183000017	putative acyl-acceptor binding pocket; other site
707183000018	Uncharacterized conserved protein [Function unknown]; Region: COG1624
707183000019	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
707183000020	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
707183000021	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
707183000022	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
707183000023	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
707183000024	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
707183000025	putative active site [active]
707183000026	PhoH-like protein; Region: PhoH; pfam02562
707183000027	Bacterial SH3 domain homologues; Region: SH3b; smart00287
707183000028	Bacterial SH3 domain homologues; Region: SH3b; smart00287
707183000029	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
707183000030	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
707183000031	HIGH motif; other site
707183000032	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
707183000033	active site
707183000034	KMSKS motif; other site
707183000035	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
707183000036	tRNA binding surface [nucleotide binding]; other site
707183000037	anticodon binding site; other site
707183000038	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
707183000039	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
707183000040	Catalytic site [active]
707183000041	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
707183000042	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
707183000043	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
707183000044	peptide chain release factor 1; Validated; Region: prfA; PRK00591
707183000045	PCRF domain; Region: PCRF; pfam03462
707183000046	RF-1 domain; Region: RF-1; pfam00472
707183000047	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
707183000048	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707183000049	S-adenosylmethionine binding site [chemical binding]; other site
707183000050	signal recognition particle protein; Provisional; Region: PRK10867
707183000051	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
707183000052	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
707183000053	P loop; other site
707183000054	GTP binding site [chemical binding]; other site
707183000055	Signal peptide binding domain; Region: SRP_SPB; pfam02978
707183000056	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14522
707183000057	tRNA (guanine-N(1)-)-methyltransferase/unknown domain fusion protein; Reviewed; Region: trmD; PRK01037
707183000058	tRNA-(guanine-N1)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmD; COG0336
707183000059	ribosomal protein L19, bacterial type; Region: rplS_bact; TIGR01024
707183000060	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
707183000061	RNA/DNA hybrid binding site [nucleotide binding]; other site
707183000062	active site
707183000063	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
707183000064	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
707183000065	catalytic site [active]
707183000066	G-X2-G-X-G-K; other site
707183000067	methionyl-tRNA synthetase; Reviewed; Region: PRK12268
707183000068	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
707183000069	active site
707183000070	HIGH motif; other site
707183000071	KMSKS motif; other site
707183000072	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
707183000073	tRNA binding surface [nucleotide binding]; other site
707183000074	anticodon binding site; other site
707183000075	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
707183000076	AAA domain; Region: AAA_30; pfam13604
707183000077	Family description; Region: UvrD_C_2; pfam13538
707183000078	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
707183000079	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
707183000080	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Saccharomyces cerevisiae biotin-apoprotein ligase (ScBLP); Region: GATase1_ScBLP_like; cd03144
707183000081	conserved cys residue [active]
707183000082	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
707183000083	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
707183000084	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
707183000085	trimer interface [polypeptide binding]; other site
707183000086	active site
707183000087	Holliday junction resolvasome, helicase subunit [DNA replication, recombination, and repair]; Region: RuvB; COG2255
707183000088	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183000089	Walker A motif; other site
707183000090	ATP binding site [chemical binding]; other site
707183000091	Walker B motif; other site
707183000092	arginine finger; other site
707183000093	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
707183000094	Type II secretory pathway, pullulanase PulA and related glycosidases [Carbohydrate transport and metabolism]; Region: PulA; COG1523
707183000095	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
707183000096	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
707183000097	active site
707183000098	catalytic site [active]
707183000099	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
707183000100	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
707183000101	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
707183000102	dimer interface [polypeptide binding]; other site
707183000103	ssDNA binding site [nucleotide binding]; other site
707183000104	tetramer (dimer of dimers) interface [polypeptide binding]; other site
707183000105	multifunctional aminopeptidase A; Provisional; Region: PRK00913
707183000106	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
707183000107	interface (dimer of trimers) [polypeptide binding]; other site
707183000108	Substrate-binding/catalytic site; other site
707183000109	Zn-binding sites [ion binding]; other site
707183000110	hypothetical protein; Provisional; Region: PRK05907
707183000111	Predicted methyltransferases [General function prediction only]; Region: COG0313
707183000112	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
707183000113	putative SAM binding site [chemical binding]; other site
707183000114	homodimer interface [polypeptide binding]; other site
707183000115	coproporphyrinogen III oxidase; Provisional; Region: PRK06294
707183000116	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
707183000117	FeS/SAM binding site; other site
707183000118	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes [Energy production and conversion]; Region: SucA; COG0567
707183000119	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
707183000120	TPP-binding site [chemical binding]; other site
707183000121	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
707183000122	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
707183000123	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
707183000124	E3 interaction surface; other site
707183000125	lipoyl attachment site [posttranslational modification]; other site
707183000126	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
707183000127	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
707183000128	uncharacterized protein, YfiH family; Region: TIGR00726
707183000129	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
707183000130	1-hydroxy-2-methyl-2-(e)-butenyl 4-diphosphate synthase [Lipid metabolism]; Region: gcpE; COG0821
707183000131	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cd02749
707183000132	ADP-ribose binding site [chemical binding]; other site
707183000133	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
707183000134	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
707183000135	catalytic loop [active]
707183000136	iron binding site [ion binding]; other site
707183000137	type III secretion system protein; Validated; Region: PRK05910
707183000138	FHIPEP family; Region: FHIPEP; pfam00771
707183000139	RNA polymerase sigma factor sigma-28; Reviewed; Region: PRK05911
707183000140	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
707183000141	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
707183000142	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
707183000143	DNA binding residues [nucleotide binding]
707183000144	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
707183000145	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
707183000146	active site
707183000147	HIGH motif; other site
707183000148	dimer interface [polypeptide binding]; other site
707183000149	KMSKS motif; other site
707183000150	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707183000151	RNA binding surface [nucleotide binding]; other site
707183000152	6-phosphogluconate dehydrogenase (decarboxylating); Region: gnd; TIGR00873
707183000153	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
707183000154	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
707183000155	GTP-binding protein LepA; Provisional; Region: PRK05433
707183000156	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
707183000157	G1 box; other site
707183000158	putative GEF interaction site [polypeptide binding]; other site
707183000159	GTP/Mg2+ binding site [chemical binding]; other site
707183000160	Switch I region; other site
707183000161	G2 box; other site
707183000162	G3 box; other site
707183000163	Switch II region; other site
707183000164	G4 box; other site
707183000165	G5 box; other site
707183000166	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
707183000167	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
707183000168	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
707183000169	ADP/ATP carrier protein family; Region: AAA; TIGR00769
707183000170	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
707183000171	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
707183000172	intersubunit interface [polypeptide binding]; other site
707183000173	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
707183000174	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
707183000175	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
707183000176	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
707183000177	ABC-ATPase subunit  interface; other site
707183000178	dimer interface [polypeptide binding]; other site
707183000179	putative PBP binding regions; other site
707183000180	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
707183000181	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
707183000182	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
707183000183	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
707183000184	ABC-ATPase subunit  interface; other site
707183000185	dimer interface [polypeptide binding]; other site
707183000186	putative PBP binding regions; other site
707183000187	1-deoxy-D-xylulose 5-phosphate reductoisomerase [Lipid metabolism]; Region: Dxr; COG0743
707183000188	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
707183000189	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
707183000190	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
707183000191	RIP metalloprotease RseP; Region: TIGR00054
707183000192	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
707183000193	active site
707183000194	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
707183000195	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
707183000196	putative substrate binding region [chemical binding]; other site
707183000197	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
707183000198	Putative serine esterase (DUF676); Region: DUF676; pfam05057
707183000199	recF protein; Region: recf; TIGR00611
707183000200	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707183000201	Walker A/P-loop; other site
707183000202	ATP binding site [chemical binding]; other site
707183000203	Q-loop/lid; other site
707183000204	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707183000205	ABC transporter signature motif; other site
707183000206	Walker B; other site
707183000207	DNA polymerase III subunit beta; Validated; Region: PRK05643
707183000208	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
707183000209	putative DNA binding surface [nucleotide binding]; other site
707183000210	dimer interface [polypeptide binding]; other site
707183000211	beta-clamp/clamp loader binding surface; other site
707183000212	beta-clamp/translesion DNA polymerase binding surface; other site
707183000213	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
707183000214	SmpB-tmRNA interface; other site
707183000215	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
707183000216	ApbE family; Region: ApbE; pfam02424
707183000217	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14181
707183000218	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
707183000219	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
707183000220	homodimer interface [polypeptide binding]; other site
707183000221	NADP binding site [chemical binding]; other site
707183000222	substrate binding site [chemical binding]; other site
707183000223	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707183000224	PLD-like domain; Region: PLDc_2; pfam13091
707183000225	putative active site [active]
707183000226	catalytic site [active]
707183000227	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
707183000228	PLD-like domain; Region: PLDc_2; pfam13091
707183000229	putative active site [active]
707183000230	catalytic site [active]
707183000231	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
707183000232	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
707183000233	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
707183000234	4-alpha-glucanotransferase; Region: Glyco_hydro_77; pfam02446
707183000235	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
707183000236	HrpJ-like domain; Region: HrpJ; pfam07201
707183000237	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
707183000238	FHIPEP family; Region: FHIPEP; pfam00771
707183000239	type III secretion system protein; Validated; Region: PRK06298
707183000240	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
707183000241	GTP-binding protein YchF; Reviewed; Region: PRK09601
707183000242	YchF GTPase; Region: YchF; cd01900
707183000243	G1 box; other site
707183000244	GTP/Mg2+ binding site [chemical binding]; other site
707183000245	Switch I region; other site
707183000246	G2 box; other site
707183000247	Switch II region; other site
707183000248	G3 box; other site
707183000249	G4 box; other site
707183000250	G5 box; other site
707183000251	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
707183000252	FAD synthase [Coenzyme metabolism]; Region: RibF; COG0196
707183000253	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
707183000254	active site
707183000255	Riboflavin kinase; Region: Flavokinase; smart00904
707183000256	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00989
707183000257	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
707183000258	RNA binding site [nucleotide binding]; other site
707183000259	active site
707183000260	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
707183000261	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
707183000262	Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; Region: InfB; COG0532
707183000263	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
707183000264	G1 box; other site
707183000265	putative GEF interaction site [polypeptide binding]; other site
707183000266	GTP/Mg2+ binding site [chemical binding]; other site
707183000267	Switch I region; other site
707183000268	G2 box; other site
707183000269	G3 box; other site
707183000270	Switch II region; other site
707183000271	G4 box; other site
707183000272	G5 box; other site
707183000273	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
707183000274	Translation-initiation factor 2; Region: IF-2; pfam11987
707183000275	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
707183000276	transcription termination factor NusA; Region: NusA; TIGR01953
707183000277	NusA N-terminal domain; Region: NusA_N; pfam08529
707183000278	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
707183000279	RNA binding site [nucleotide binding]; other site
707183000280	homodimer interface [polypeptide binding]; other site
707183000281	NusA-like KH domain; Region: KH_5; pfam13184
707183000282	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
707183000283	G-X-X-G motif; other site
707183000284	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
707183000285	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
707183000286	RNA binding site [nucleotide binding]; other site
707183000287	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
707183000288	RNA binding site [nucleotide binding]; other site
707183000289	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
707183000290	RNA binding site [nucleotide binding]; other site
707183000291	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
707183000292	RNA binding site [nucleotide binding]; other site
707183000293	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
707183000294	RNA binding site [nucleotide binding]; other site
707183000295	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
707183000296	RNA binding site [nucleotide binding]; other site
707183000297	domain interface; other site
707183000298	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
707183000299	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
707183000300	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
707183000301	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
707183000302	Flagellar biogenesis protein [Cell motility and secretion]; Region: FliO; COG3190
707183000303	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
707183000304	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
707183000305	active site
707183000306	motif I; other site
707183000307	motif II; other site
707183000308	enoyl-[acyl-carrier-protein] reductase; Region: PLN02730
707183000309	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
707183000310	NAD binding site [chemical binding]; other site
707183000311	homotetramer interface [polypeptide binding]; other site
707183000312	homodimer interface [polypeptide binding]; other site
707183000313	substrate binding site [chemical binding]; other site
707183000314	active site
707183000315	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
707183000316	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707183000317	RNA binding surface [nucleotide binding]; other site
707183000318	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
707183000319	active site
707183000320	A/G-specific adenine glycosylase; Region: mutY; TIGR01084
707183000321	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
707183000322	minor groove reading motif; other site
707183000323	helix-hairpin-helix signature motif; other site
707183000324	substrate binding pocket [chemical binding]; other site
707183000325	active site
707183000326	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
707183000327	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
707183000328	DNA binding and oxoG recognition site [nucleotide binding]
707183000329	Uncharacterized conserved protein [Function unknown]; Region: COG0327
707183000330	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
707183000331	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
707183000332	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
707183000333	ring oligomerisation interface [polypeptide binding]; other site
707183000334	ATP/Mg binding site [chemical binding]; other site
707183000335	stacking interactions; other site
707183000336	hinge regions; other site
707183000337	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
707183000338	oligomerisation interface [polypeptide binding]; other site
707183000339	mobile loop; other site
707183000340	roof hairpin; other site
707183000341	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
707183000342	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
707183000343	active site
707183000344	Zn binding site [ion binding]; other site
707183000345	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
707183000346	Clp amino terminal domain; Region: Clp_N; pfam02861
707183000347	Clp amino terminal domain; Region: Clp_N; pfam02861
707183000348	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183000349	Walker A motif; other site
707183000350	ATP binding site [chemical binding]; other site
707183000351	Walker B motif; other site
707183000352	arginine finger; other site
707183000353	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183000354	Walker A motif; other site
707183000355	ATP binding site [chemical binding]; other site
707183000356	Walker B motif; other site
707183000357	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
707183000358	Uncharacterized conserved protein [Function unknown]; Region: COG2912
707183000359	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
707183000360	IncA protein; Region: IncA; pfam04156
707183000361	Acetyl-CoA carboxylase, central region; Region: ACC_central; pfam08326
707183000362	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
707183000363	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
707183000364	substrate binding site [chemical binding]; other site
707183000365	hexamer interface [polypeptide binding]; other site
707183000366	metal binding site [ion binding]; metal-binding site
707183000367	elongation factor P; Provisional; Region: PRK12426
707183000368	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
707183000369	RNA binding site [nucleotide binding]; other site
707183000370	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
707183000371	RNA binding site [nucleotide binding]; other site
707183000372	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
707183000373	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
707183000374	carboxyltransferase (CT) interaction site; other site
707183000375	biotinylation site [posttranslational modification]; other site
707183000376	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
707183000377	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
707183000378	ATP-grasp domain; Region: ATP-grasp_4; cl17255
707183000379	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
707183000380	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
707183000381	23S rRNA interface [nucleotide binding]; other site
707183000382	L3 interface [polypeptide binding]; other site
707183000383	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
707183000384	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
707183000385	NlpC/P60 family; Region: NLPC_P60; cl17555
707183000386	adenylate kinase; Reviewed; Region: adk; PRK00279
707183000387	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
707183000388	AMP-binding site [chemical binding]; other site
707183000389	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
707183000390	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
707183000391	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707183000392	dimer interface [polypeptide binding]; other site
707183000393	conserved gate region; other site
707183000394	putative PBP binding loops; other site
707183000395	ABC-ATPase subunit interface; other site
707183000396	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
707183000397	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707183000398	Walker A/P-loop; other site
707183000399	ATP binding site [chemical binding]; other site
707183000400	Q-loop/lid; other site
707183000401	ABC transporter signature motif; other site
707183000402	Walker B; other site
707183000403	D-loop; other site
707183000404	H-loop/switch region; other site
707183000405	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
707183000406	Methyltransferase domain; Region: Methyltransf_23; pfam13489
707183000407	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707183000408	S-adenosylmethionine binding site [chemical binding]; other site
707183000409	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
707183000410	Serine hydrolase (FSH1); Region: FSH1; pfam03959
707183000411	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
707183000412	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
707183000413	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
707183000414	active site
707183000415	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
707183000416	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
707183000417	conserved hypothetical integral membrane protein; Region: TIGR00697
707183000418	Predicted metal-binding protein related to the C-terminal domain of SecA [General function prediction only]; Region: COG3318
707183000419	SEC-C motif; Region: SEC-C; pfam02810
707183000420	potential protein location (hypothetical protein E11023_00740 [Chlamydia trachomatis E/11023]) that overlaps RNA (tRNA-T)
707183000421	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
707183000422	Catalytic domain of Protein Kinases; Region: PKc; cd00180
707183000423	active site
707183000424	ATP binding site [chemical binding]; other site
707183000425	substrate binding site [chemical binding]; other site
707183000426	activation loop (A-loop); other site
707183000427	Uncharacterized conserved protein [Function unknown]; Region: COG1262
707183000428	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
707183000429	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
707183000430	DNA ligase, NAD-dependent; Region: dnlj; TIGR00575
707183000431	nucleotide binding pocket [chemical binding]; other site
707183000432	K-X-D-G motif; other site
707183000433	catalytic site [active]
707183000434	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
707183000435	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
707183000436	Helix-hairpin-helix motif; Region: HHH; pfam00633
707183000437	helix-hairpin-helix signature motif; other site
707183000438	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
707183000439	Dimer interface [polypeptide binding]; other site
707183000440	BRCT sequence motif; other site
707183000441	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
707183000442	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
707183000443	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
707183000444	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
707183000445	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
707183000446	FtsX-like permease family; Region: FtsX; pfam02687
707183000447	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
707183000448	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
707183000449	Walker A/P-loop; other site
707183000450	ATP binding site [chemical binding]; other site
707183000451	Q-loop/lid; other site
707183000452	ABC transporter signature motif; other site
707183000453	Walker B; other site
707183000454	D-loop; other site
707183000455	H-loop/switch region; other site
707183000456	membrane-attack complex / perforin; Region: MACPF; smart00457
707183000457	Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; Region: MIR; smart00472
707183000458	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707183000459	PLD-like domain; Region: PLDc_2; pfam13091
707183000460	putative active site [active]
707183000461	catalytic site [active]
707183000462	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
707183000463	PLD-like domain; Region: PLDc_2; pfam13091
707183000464	putative active site [active]
707183000465	catalytic site [active]
707183000466	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707183000467	PLD-like domain; Region: PLDc_2; pfam13091
707183000468	putative active site [active]
707183000469	catalytic site [active]
707183000470	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707183000471	PLD-like domain; Region: PLDc_2; pfam13091
707183000472	putative active site [active]
707183000473	catalytic site [active]
707183000474	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707183000475	PLD-like domain; Region: PLDc_2; pfam13091
707183000476	putative active site [active]
707183000477	catalytic site [active]
707183000478	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
707183000479	PLD-like domain; Region: PLDc_2; pfam13091
707183000480	putative active site [active]
707183000481	catalytic site [active]
707183000482	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707183000483	potential frameshift: common BLAST hit: gi|15835056|ref|NP_296815.1| adherence factor
707183000484	TcdB toxin N-terminal helical domain; Region: TcdB_N; pfam12918
707183000485	TcdA/TcdB catalytic glycosyltransferase domain; Region: TcdA_TcdB; pfam12919
707183000486	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
707183000487	Protein of unknown function (DUF3491); Region: DUF3491; pfam11996
707183000488	trp operon repressor, proteobacterial; Region: TrpR; TIGR01321
707183000489	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
707183000490	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
707183000491	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707183000492	catalytic residue [active]
707183000493	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
707183000494	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
707183000495	substrate binding site [chemical binding]; other site
707183000496	active site
707183000497	catalytic residues [active]
707183000498	heterodimer interface [polypeptide binding]; other site
707183000499	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
707183000500	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
707183000501	peptide binding site [polypeptide binding]; other site
707183000502	putative disulfide oxidoreductase; Provisional; Region: PRK00611
707183000503	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
707183000504	Thioredoxin; Region: Thioredoxin_4; cl17273
707183000505	Vitamin K epoxide reductase (VKOR) family; Region: VKOR; cl01729
707183000506	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
707183000507	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707183000508	Walker A/P-loop; other site
707183000509	ATP binding site [chemical binding]; other site
707183000510	Q-loop/lid; other site
707183000511	ABC transporter signature motif; other site
707183000512	Walker B; other site
707183000513	D-loop; other site
707183000514	H-loop/switch region; other site
707183000515	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
707183000516	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
707183000517	Ligand binding site; other site
707183000518	oligomer interface; other site
707183000519	CTP synthetase; Validated; Region: pyrG; PRK05380
707183000520	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
707183000521	Catalytic site [active]
707183000522	active site
707183000523	UTP binding site [chemical binding]; other site
707183000524	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
707183000525	active site
707183000526	putative oxyanion hole; other site
707183000527	catalytic triad [active]
707183000528	Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) [DNA replication, recombination, and repair]; Region: COG0816
707183000529	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
707183000530	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
707183000531	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
707183000532	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
707183000533	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
707183000534	putative active site [active]
707183000535	DNA polymerase III subunit delta'; Validated; Region: PRK05917
707183000536	DNA polymerase III subunit delta'; Validated; Region: PRK08485
707183000537	thymidylate kinase; Validated; Region: tmk; PRK00698
707183000538	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
707183000539	TMP-binding site; other site
707183000540	ATP-binding site [chemical binding]; other site
707183000541	DNA gyrase, A subunit; Region: gyrA; TIGR01063
707183000542	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
707183000543	CAP-like domain; other site
707183000544	active site
707183000545	primary dimer interface [polypeptide binding]; other site
707183000546	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707183000547	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707183000548	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707183000549	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707183000550	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707183000551	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707183000552	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
707183000553	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707183000554	ATP binding site [chemical binding]; other site
707183000555	Mg2+ binding site [ion binding]; other site
707183000556	G-X-G motif; other site
707183000557	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
707183000558	anchoring element; other site
707183000559	dimer interface [polypeptide binding]; other site
707183000560	ATP binding site [chemical binding]; other site
707183000561	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
707183000562	active site
707183000563	putative metal-binding site [ion binding]; other site
707183000564	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
707183000565	Protein of unknown function (DUF721); Region: DUF721; pfam05258
707183000566	queuine tRNA-ribosyltransferase; Provisional; Region: PRK01008
707183000567	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
707183000568	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
707183000569	MgtE intracellular N domain; Region: MgtE_N; pfam03448
707183000570	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
707183000571	Divalent cation transporter; Region: MgtE; pfam01769
707183000572	Metal-dependent proteases with possible chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: QRI7; COG0533
707183000573	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
707183000574	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
707183000575	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
707183000576	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
707183000577	peptide binding site [polypeptide binding]; other site
707183000578	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
707183000579	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707183000580	dimer interface [polypeptide binding]; other site
707183000581	conserved gate region; other site
707183000582	putative PBP binding loops; other site
707183000583	ABC-ATPase subunit interface; other site
707183000584	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
707183000585	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707183000586	dimer interface [polypeptide binding]; other site
707183000587	conserved gate region; other site
707183000588	putative PBP binding loops; other site
707183000589	ABC-ATPase subunit interface; other site
707183000590	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707183000591	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
707183000592	Walker A/P-loop; other site
707183000593	ATP binding site [chemical binding]; other site
707183000594	Q-loop/lid; other site
707183000595	ABC transporter signature motif; other site
707183000596	Walker B; other site
707183000597	D-loop; other site
707183000598	H-loop/switch region; other site
707183000599	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
707183000600	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
707183000601	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707183000602	Walker A/P-loop; other site
707183000603	ATP binding site [chemical binding]; other site
707183000604	Q-loop/lid; other site
707183000605	ABC transporter signature motif; other site
707183000606	Walker B; other site
707183000607	D-loop; other site
707183000608	H-loop/switch region; other site
707183000609	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
707183000610	Protein of unknown function (DUF1186); Region: DUF1186; pfam06685
707183000611	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
707183000612	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
707183000613	transmembrane helices; other site
707183000614	diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional; Region: PRK07085
707183000615	active site
707183000616	ADP/pyrophosphate binding site [chemical binding]; other site
707183000617	dimerization interface [polypeptide binding]; other site
707183000618	allosteric effector site; other site
707183000619	fructose-1,6-bisphosphate binding site; other site
707183000620	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
707183000621	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
707183000622	diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional; Region: PRK07085
707183000623	pyrophosphate-dependent phosphofructokinase; Region: PLN02251
707183000624	active site
707183000625	ADP/pyrophosphate binding site [chemical binding]; other site
707183000626	dimerization interface [polypeptide binding]; other site
707183000627	allosteric effector site; other site
707183000628	fructose-1,6-bisphosphate binding site; other site
707183000629	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
707183000630	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
707183000631	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
707183000632	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
707183000633	HIGH motif; other site
707183000634	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
707183000635	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
707183000636	active site
707183000637	KMSKS motif; other site
707183000638	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
707183000639	tRNA binding surface [nucleotide binding]; other site
707183000640	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00615
707183000641	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
707183000642	inhibitor-cofactor binding pocket; inhibition site
707183000643	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707183000644	catalytic residue [active]
707183000645	Putative transcriptional regulator [Transcription]; Region: COG1678
707183000646	Uncharacterized conserved protein [Function unknown]; Region: COG1259
707183000647	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
707183000648	tetramer (dimer of dimers) interface [polypeptide binding]; other site
707183000649	active site
707183000650	dimer interface [polypeptide binding]; other site
707183000651	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
707183000652	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
707183000653	putative active site; other site
707183000654	catalytic residue [active]
707183000655	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
707183000656	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
707183000657	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
707183000658	Ligand Binding Site [chemical binding]; other site
707183000659	Predicted acid phosphatase [General function prediction only]; Region: SurE; COG0496
707183000660	prenyltransferase; Reviewed; Region: ubiA; PRK12876
707183000661	UbiA prenyltransferase family; Region: UbiA; pfam01040
707183000662	aromatic acid decarboxylase; Validated; Region: PRK05920
707183000663	Flavoprotein; Region: Flavoprotein; pfam02441
707183000664	Uncharacterized conserved protein [Function unknown]; Region: COG1284
707183000665	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
707183000666	IncA protein; Region: IncA; pfam04156
707183000667	IncA protein; Region: IncA; pfam04156
707183000668	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
707183000669	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
707183000670	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
707183000671	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
707183000672	Na2 binding site [ion binding]; other site
707183000673	putative substrate binding site 1 [chemical binding]; other site
707183000674	Na binding site 1 [ion binding]; other site
707183000675	putative substrate binding site 2 [chemical binding]; other site
707183000676	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707183000677	putative substrate translocation pore; other site
707183000678	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
707183000679	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
707183000680	ligand binding site [chemical binding]; other site
707183000681	flexible hinge region; other site
707183000682	acyl carrier protein; Provisional; Region: acpP; PRK00982
707183000683	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
707183000684	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
707183000685	NAD(P) binding site [chemical binding]; other site
707183000686	homotetramer interface [polypeptide binding]; other site
707183000687	homodimer interface [polypeptide binding]; other site
707183000688	active site
707183000689	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
707183000690	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
707183000691	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
707183000692	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
707183000693	dimer interface [polypeptide binding]; other site
707183000694	active site
707183000695	CoA binding pocket [chemical binding]; other site
707183000696	recombination protein RecR; Region: recR; TIGR00615
707183000697	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
707183000698	putative active site [active]
707183000699	putative metal-binding site [ion binding]; other site
707183000700	tetramer interface [polypeptide binding]; other site
707183000701	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
707183000702	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707183000703	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707183000704	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707183000705	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707183000706	Surface antigen; Region: Bac_surface_Ag; pfam01103
707183000707	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: HlpA; COG2825
707183000708	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
707183000709	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
707183000710	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
707183000711	trimer interface [polypeptide binding]; other site
707183000712	active site
707183000713	UDP-GlcNAc binding site [chemical binding]; other site
707183000714	lipid binding site [chemical binding]; lipid-binding site
707183000715	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
707183000716	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
707183000717	tetramer interface [polypeptide binding]; other site
707183000718	TPP-binding site [chemical binding]; other site
707183000719	heterodimer interface [polypeptide binding]; other site
707183000720	phosphorylation loop region [posttranslational modification]
707183000721	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
707183000722	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
707183000723	alpha subunit interface [polypeptide binding]; other site
707183000724	TPP binding site [chemical binding]; other site
707183000725	heterodimer interface [polypeptide binding]; other site
707183000726	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707183000727	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; Region: PDHac_trf_mito; TIGR01349
707183000728	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
707183000729	E3 interaction surface; other site
707183000730	lipoyl attachment site [posttranslational modification]; other site
707183000731	e3 binding domain; Region: E3_binding; pfam02817
707183000732	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
707183000733	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
707183000734	homodimer interface [polypeptide binding]; other site
707183000735	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
707183000736	active site pocket [active]
707183000737	chromosomal replication initiation protein; Provisional; Region: PRK12422
707183000738	DnaA N-terminal domain; Region: DnaA_N; pfam11638
707183000739	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183000740	Walker A motif; other site
707183000741	ATP binding site [chemical binding]; other site
707183000742	Walker B motif; other site
707183000743	arginine finger; other site
707183000744	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
707183000745	DnaA box-binding interface [nucleotide binding]; other site
707183000746	putative inner membrane protein translocase component YidC; Provisional; Region: PRK01001
707183000747	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
707183000748	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
707183000749	CAAX protease self-immunity; Region: Abi; pfam02517
707183000750	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
707183000751	homodimer interface [polypeptide binding]; other site
707183000752	metal binding site [ion binding]; metal-binding site
707183000753	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
707183000754	Domain of unknown function DUF21; Region: DUF21; pfam01595
707183000755	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
707183000756	Transporter associated domain; Region: CorC_HlyC; smart01091
707183000757	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
707183000758	Domain of unknown function DUF21; Region: DUF21; pfam01595
707183000759	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
707183000760	Transporter associated domain; Region: CorC_HlyC; smart01091
707183000761	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
707183000762	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
707183000763	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707183000764	catalytic residue [active]
707183000765	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
707183000766	Protein phosphatase 2C; Region: PP2C; pfam00481
707183000767	active site
707183000768	Uncharacterized conserved protein [Function unknown]; Region: COG5465
707183000769	DNA polymerase III subunit epsilon; Validated; Region: PRK06309
707183000770	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
707183000771	active site
707183000772	catalytic site [active]
707183000773	substrate binding site [chemical binding]; other site
707183000774	Protein of unknown function (DUF3820); Region: DUF3820; cl01411
707183000775	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
707183000776	nucleosidase; Provisional; Region: PRK05634
707183000777	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
707183000778	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
707183000779	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707183000780	Walker A/P-loop; other site
707183000781	ATP binding site [chemical binding]; other site
707183000782	Q-loop/lid; other site
707183000783	ABC transporter signature motif; other site
707183000784	Walker B; other site
707183000785	D-loop; other site
707183000786	H-loop/switch region; other site
707183000787	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
707183000788	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
707183000789	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
707183000790	IHF - DNA interface [nucleotide binding]; other site
707183000791	IHF dimer interface [polypeptide binding]; other site
707183000792	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
707183000793	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
707183000794	active site
707183000795	metal binding site [ion binding]; metal-binding site
707183000796	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
707183000797	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
707183000798	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707183000799	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707183000800	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
707183000801	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
707183000802	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
707183000803	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
707183000804	MraW methylase family; Region: Methyltransf_5; pfam01795
707183000805	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707183000806	TPR motif; other site
707183000807	binding surface
707183000808	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
707183000809	DnaA N-terminal domain; Region: DnaA_N; pfam11638
707183000810	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183000811	Walker A motif; other site
707183000812	ATP binding site [chemical binding]; other site
707183000813	Walker B motif; other site
707183000814	arginine finger; other site
707183000815	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
707183000816	DnaA box-binding interface [nucleotide binding]; other site
707183000817	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
707183000818	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
707183000819	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK01024
707183000820	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC [Energy production and conversion]; Region: NqrC; COG2869
707183000821	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
707183000822	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD [Energy production and conversion]; Region: NqrD; COG1347
707183000823	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK01061
707183000824	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
707183000825	lipoyl attachment site [posttranslational modification]; other site
707183000826	Chlamydial GcvH-like protein upstream region protein; Region: near_not_gcvH; TIGR03076
707183000827	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
707183000828	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707183000829	putative active site [active]
707183000830	catalytic site [active]
707183000831	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707183000832	putative active site [active]
707183000833	catalytic site [active]
707183000834	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
707183000835	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
707183000836	Clp amino terminal domain; Region: Clp_N; pfam02861
707183000837	Clp amino terminal domain; Region: Clp_N; pfam02861
707183000838	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183000839	Walker A motif; other site
707183000840	ATP binding site [chemical binding]; other site
707183000841	Walker B motif; other site
707183000842	arginine finger; other site
707183000843	UvrB/uvrC motif; Region: UVR; pfam02151
707183000844	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183000845	Walker A motif; other site
707183000846	ATP binding site [chemical binding]; other site
707183000847	Walker B motif; other site
707183000848	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
707183000849	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
707183000850	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
707183000851	Ligand Binding Site [chemical binding]; other site
707183000852	Helix-turn-helix domain; Region: HTH_17; pfam12728
707183000853	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
707183000854	active site
707183000855	phosphorylation site [posttranslational modification]
707183000856	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
707183000857	active site
707183000858	phosphorylation site [posttranslational modification]
707183000859	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
707183000860	trimer interface [polypeptide binding]; other site
707183000861	active site
707183000862	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
707183000863	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
707183000864	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
707183000865	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
707183000866	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
707183000867	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
707183000868	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
707183000869	active site
707183000870	substrate binding site [chemical binding]; other site
707183000871	metal binding site [ion binding]; metal-binding site
707183000872	ribonuclease III; Reviewed; Region: rnc; PRK00102
707183000873	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
707183000874	dimerization interface [polypeptide binding]; other site
707183000875	active site
707183000876	metal binding site [ion binding]; metal-binding site
707183000877	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
707183000878	dsRNA binding site [nucleotide binding]; other site
707183000879	DNA repair protein RadA; Provisional; Region: PRK11823
707183000880	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
707183000881	Walker A motif/ATP binding site; other site
707183000882	ATP binding site [chemical binding]; other site
707183000883	Walker B motif; other site
707183000884	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
707183000885	porphobilinogen deaminase; Provisional; Region: PRK01066
707183000886	Porphobilinogen deaminase, dipyromethane cofactor binding domain; Region: Porphobil_deam; pfam01379
707183000887	serine/threonine-protein kinase; Reviewed; Region: pknD; PRK13184
707183000888	Catalytic domain of Protein Kinases; Region: PKc; cd00180
707183000889	active site
707183000890	ATP binding site [chemical binding]; other site
707183000891	substrate binding site [chemical binding]; other site
707183000892	activation loop (A-loop); other site
707183000893	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
707183000894	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
707183000895	HIGH motif; other site
707183000896	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
707183000897	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
707183000898	active site
707183000899	KMSKS motif; other site
707183000900	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
707183000901	tRNA binding surface [nucleotide binding]; other site
707183000902	anticodon binding site; other site
707183000903	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
707183000904	V-type ATP synthase subunit K; Provisional; Region: PRK09621
707183000905	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
707183000906	V-type ATP synthase subunit I; Validated; Region: PRK05771
707183000907	Protein of unknown function (DUF1319); Region: DUF1319; pfam07028
707183000908	V-type ATP synthase subunit D; Provisional; Region: PRK02195
707183000909	V-type ATP synthase subunit B; Provisional; Region: PRK02118
707183000910	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707183000911	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
707183000912	Walker A motif homologous position; other site
707183000913	Walker B motif; other site
707183000914	V-type ATP synthase subunit A; Provisional; Region: PRK04192
707183000915	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707183000916	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
707183000917	Walker A motif/ATP binding site; other site
707183000918	Walker B motif; other site
707183000919	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
707183000920	Protein of unknown function (DUF2764); Region: DUF2764; pfam10962
707183000921	V-type ATP synthase subunit E; Provisional; Region: PRK01005
707183000922	V-type ATP synthase subunit E; Provisional; Region: PRK01558
707183000923	transaldolase-like protein; Provisional; Region: PTZ00411
707183000924	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
707183000925	active site
707183000926	dimer interface [polypeptide binding]; other site
707183000927	catalytic residue [active]
707183000928	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
707183000929	DNA-directed RNA polymerase, beta' subunit, predominant form; Region: rpoC_TIGR; TIGR02386
707183000930	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
707183000931	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
707183000932	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
707183000933	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
707183000934	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
707183000935	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
707183000936	DNA binding site [nucleotide binding]
707183000937	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
707183000938	RNA polymerase beta subunit; Region: RNA_pol_Rpb2_1; pfam04563
707183000939	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
707183000940	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
707183000941	DNA-directed RNA polymerase, beta subunit; Region: rpoB; TIGR02013
707183000942	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
707183000943	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
707183000944	RPB12 interaction site [polypeptide binding]; other site
707183000945	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
707183000946	RPB3 interaction site [polypeptide binding]; other site
707183000947	RPB1 interaction site [polypeptide binding]; other site
707183000948	RPB11 interaction site [polypeptide binding]; other site
707183000949	RPB10 interaction site [polypeptide binding]; other site
707183000950	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
707183000951	L11 interface [polypeptide binding]; other site
707183000952	putative EF-Tu interaction site [polypeptide binding]; other site
707183000953	putative EF-G interaction site [polypeptide binding]; other site
707183000954	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
707183000955	23S rRNA interface [nucleotide binding]; other site
707183000956	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
707183000957	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
707183000958	mRNA/rRNA interface [nucleotide binding]; other site
707183000959	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
707183000960	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
707183000961	putative thiostrepton binding site; other site
707183000962	23S rRNA interface [nucleotide binding]; other site
707183000963	L7/L12 interface [polypeptide binding]; other site
707183000964	L25 interface [polypeptide binding]; other site
707183000965	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
707183000966	transcription termination/antitermination factor NusG; Region: nusG; TIGR00922
707183000967	putative homodimer interface [polypeptide binding]; other site
707183000968	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
707183000969	heterodimer interface [polypeptide binding]; other site
707183000970	homodimer interface [polypeptide binding]; other site
707183000971	Preprotein translocase subunit SecE [Intracellular trafficking and secretion]; Region: SecE; COG0690
707183000972	elongation factor Tu; Reviewed; Region: PRK12735
707183000973	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
707183000974	G1 box; other site
707183000975	GEF interaction site [polypeptide binding]; other site
707183000976	GTP/Mg2+ binding site [chemical binding]; other site
707183000977	Switch I region; other site
707183000978	G2 box; other site
707183000979	G3 box; other site
707183000980	Switch II region; other site
707183000981	G4 box; other site
707183000982	G5 box; other site
707183000983	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
707183000984	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
707183000985	Antibiotic Binding Site [chemical binding]; other site
707183000986	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
707183000987	rRNA binding site [nucleotide binding]; other site
707183000988	predicted 30S ribosome binding site; other site
707183000989	Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]; Region: sufE; COG2166
707183000990	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
707183000991	active site
707183000992	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
707183000993	triosephosphate isomerase; Provisional; Region: PRK14565
707183000994	substrate binding site [chemical binding]; other site
707183000995	dimer interface [polypeptide binding]; other site
707183000996	catalytic triad [active]
707183000997	Exonuclease VII, large subunit [DNA replication, recombination, and repair]; Region: XseA; COG1570
707183000998	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
707183000999	generic binding surface II; other site
707183001000	generic binding surface I; other site
707183001001	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
707183001002	Deoxyxylulose-5-phosphate synthase [Coenzyme metabolism / Lipid metabolism]; Region: Dxs; COG1154
707183001003	1-deoxy-D-xylulose-5-phosphate synthase; Region: DXP_synthase_N; pfam13292
707183001004	TPP-binding site [chemical binding]; other site
707183001005	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
707183001006	PYR/PP interface [polypeptide binding]; other site
707183001007	dimer interface [polypeptide binding]; other site
707183001008	TPP binding site [chemical binding]; other site
707183001009	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707183001010	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
707183001011	pyruvate kinase; Region: pyruv_kin; TIGR01064
707183001012	domain interfaces; other site
707183001013	active site
707183001014	excinuclease ABC subunit A; Provisional; Region: PRK00635
707183001015	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707183001016	Walker A/P-loop; other site
707183001017	ATP binding site [chemical binding]; other site
707183001018	Q-loop/lid; other site
707183001019	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
707183001020	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
707183001021	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707183001022	Walker A/P-loop; other site
707183001023	ATP binding site [chemical binding]; other site
707183001024	Q-loop/lid; other site
707183001025	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707183001026	ABC transporter signature motif; other site
707183001027	Walker B; other site
707183001028	D-loop; other site
707183001029	H-loop/switch region; other site
707183001030	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707183001031	Walker A/P-loop; other site
707183001032	ATP binding site [chemical binding]; other site
707183001033	Q-loop/lid; other site
707183001034	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707183001035	Q-loop/lid; other site
707183001036	ABC transporter signature motif; other site
707183001037	Walker B; other site
707183001038	D-loop; other site
707183001039	H-loop/switch region; other site
707183001040	DNA polymerase III subunits gamma and tau; Validated; Region: PRK06305
707183001041	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183001042	Walker A motif; other site
707183001043	ATP binding site [chemical binding]; other site
707183001044	Walker B motif; other site
707183001045	arginine finger; other site
707183001046	hypothetical protein; Validated; Region: PRK00153
707183001047	phosphoenolpyruvate-protein phosphotransferase; Region: PTS_I_fam; TIGR01417
707183001048	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
707183001049	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
707183001050	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
707183001051	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
707183001052	dimerization domain swap beta strand [polypeptide binding]; other site
707183001053	regulatory protein interface [polypeptide binding]; other site
707183001054	active site
707183001055	regulatory phosphorylation site [posttranslational modification]; other site
707183001056	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
707183001057	Competence protein; Region: Competence; pfam03772
707183001058	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
707183001059	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
707183001060	tetramer interface [polypeptide binding]; other site
707183001061	TPP-binding site [chemical binding]; other site
707183001062	heterodimer interface [polypeptide binding]; other site
707183001063	phosphorylation loop region [posttranslational modification]
707183001064	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
707183001065	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
707183001066	alpha subunit interface [polypeptide binding]; other site
707183001067	TPP binding site [chemical binding]; other site
707183001068	heterodimer interface [polypeptide binding]; other site
707183001069	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707183001070	chaperone protein DnaJ; Provisional; Region: PRK14284
707183001071	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
707183001072	HSP70 interaction site [polypeptide binding]; other site
707183001073	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
707183001074	Zn binding sites [ion binding]; other site
707183001075	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
707183001076	dimer interface [polypeptide binding]; other site
707183001077	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
707183001078	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
707183001079	Glycoprotease family; Region: Peptidase_M22; pfam00814
707183001080	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
707183001081	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183001082	Walker A motif; other site
707183001083	ATP binding site [chemical binding]; other site
707183001084	Walker B motif; other site
707183001085	arginine finger; other site
707183001086	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
707183001087	ribonuclease Z; Region: RNase_Z; TIGR02651
707183001088	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
707183001089	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
707183001090	active site
707183001091	Int/Topo IB signature motif; other site
707183001092	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
707183001093	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
707183001094	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
707183001095	ABC transporter; Region: ABC_tran_2; pfam12848
707183001096	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
707183001097	Maf-like protein; Region: Maf; pfam02545
707183001098	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
707183001099	active site
707183001100	dimer interface [polypeptide binding]; other site
707183001101	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
707183001102	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
707183001103	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
707183001104	active site
707183001105	catalytic residues [active]
707183001106	metal binding site [ion binding]; metal-binding site
707183001107	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
707183001108	dimethyladenosine transferase; Region: ksgA; TIGR00755
707183001109	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
707183001110	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
707183001111	catalytic residues [active]
707183001112	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
707183001113	dihydrodipicolinate synthase; Region: dapA; TIGR00674
707183001114	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
707183001115	inhibitor site; inhibition site
707183001116	active site
707183001117	dimer interface [polypeptide binding]; other site
707183001118	catalytic residue [active]
707183001119	aspartate kinase; Provisional; Region: PRK05925
707183001120	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
707183001121	putative catalytic residues [active]
707183001122	nucleotide binding site [chemical binding]; other site
707183001123	aspartate binding site [chemical binding]; other site
707183001124	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK08664
707183001125	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
707183001126	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
707183001127	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
707183001128	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
707183001129	5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; Region: AroA; COG0128
707183001130	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
707183001131	hinge; other site
707183001132	active site
707183001133	shikimate kinase; Provisional; Region: PRK00625
707183001134	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
707183001135	ADP binding site [chemical binding]; other site
707183001136	magnesium binding site [ion binding]; other site
707183001137	putative shikimate binding site; other site
707183001138	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
707183001139	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
707183001140	Tetramer interface [polypeptide binding]; other site
707183001141	active site
707183001142	FMN-binding site [chemical binding]; other site
707183001143	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
707183001144	active site
707183001145	dimer interface [polypeptide binding]; other site
707183001146	metal binding site [ion binding]; metal-binding site
707183001147	bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase protein; Reviewed; Region: aroDE; PRK09310
707183001148	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
707183001149	active site
707183001150	catalytic residue [active]
707183001151	dimer interface [polypeptide binding]; other site
707183001152	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
707183001153	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
707183001154	shikimate binding site; other site
707183001155	NAD(P) binding site [chemical binding]; other site
707183001156	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
707183001157	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
707183001158	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) [Amino acid    transport and metabolism]; Region: COG1945
707183001159	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
707183001160	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
707183001161	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
707183001162	malate dehydrogenase; Provisional; Region: PRK05442
707183001163	Chloroplast-like malate dehydrogenases; Region: MDH_choloroplast_like; cd01338
707183001164	NAD(P) binding site [chemical binding]; other site
707183001165	dimer interface [polypeptide binding]; other site
707183001166	malate binding site [chemical binding]; other site
707183001167	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14095
707183001168	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
707183001169	active site
707183001170	dimer interface [polypeptide binding]; other site
707183001171	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
707183001172	dimer interface [polypeptide binding]; other site
707183001173	active site
707183001174	GTPases [General function prediction only]; Region: HflX; COG2262
707183001175	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
707183001176	HflX GTPase family; Region: HflX; cd01878
707183001177	G1 box; other site
707183001178	GTP/Mg2+ binding site [chemical binding]; other site
707183001179	Switch I region; other site
707183001180	G2 box; other site
707183001181	G3 box; other site
707183001182	Switch II region; other site
707183001183	G4 box; other site
707183001184	G5 box; other site
707183001185	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
707183001186	putative hydrolase; Provisional; Region: PRK02113
707183001187	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
707183001188	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
707183001189	substrate binding pocket [chemical binding]; other site
707183001190	membrane-bound complex binding site; other site
707183001191	hinge residues; other site
707183001192	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroA; COG2876
707183001193	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
707183001194	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
707183001195	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
707183001196	nucleotide binding site/active site [active]
707183001197	Uncharacterized conserved protein related to MYG1 family [Function unknown]; Region: COG4286
707183001198	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
707183001199	hypothetical protein; Validated; Region: PRK00647
707183001200	Protein of unknown function (DUF1207); Region: DUF1207; pfam06727
707183001201	LL-diaminopimelate aminotransferase; Region: DAPAT_plant; TIGR03542
707183001202	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
707183001203	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707183001204	homodimer interface [polypeptide binding]; other site
707183001205	catalytic residue [active]
707183001206	ABC transporter substrate binding protein; Region: ABC_sub_bind; pfam04392
707183001207	prolyl-tRNA synthetase; Provisional; Region: PRK09194
707183001208	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
707183001209	dimer interface [polypeptide binding]; other site
707183001210	motif 1; other site
707183001211	active site
707183001212	motif 2; other site
707183001213	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
707183001214	putative deacylase active site [active]
707183001215	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
707183001216	active site
707183001217	motif 3; other site
707183001218	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
707183001219	anticodon binding site; other site
707183001220	Transcriptional regulator of heat shock gene [Transcription]; Region: HrcA; COG1420
707183001221	GrpE; Region: GrpE; pfam01025
707183001222	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
707183001223	dimer interface [polypeptide binding]; other site
707183001224	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
707183001225	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
707183001226	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
707183001227	nucleotide binding site [chemical binding]; other site
707183001228	NEF interaction site [polypeptide binding]; other site
707183001229	SBD interface [polypeptide binding]; other site
707183001230	Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]; Region: NtpF; COG2811
707183001231	Exoribonuclease R [Transcription]; Region: VacB; COG0557
707183001232	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
707183001233	RNB domain; Region: RNB; pfam00773
707183001234	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
707183001235	Putative zinc ribbon domain; Region: DUF164; pfam02591
707183001236	KpsF/GutQ family protein; Region: kpsF; TIGR00393
707183001237	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
707183001238	putative active site [active]
707183001239	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
707183001240	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
707183001241	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
707183001242	E3 interaction surface; other site
707183001243	lipoyl attachment site [posttranslational modification]; other site
707183001244	e3 binding domain; Region: E3_binding; pfam02817
707183001245	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
707183001246	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
707183001247	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
707183001248	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
707183001249	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
707183001250	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
707183001251	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
707183001252	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
707183001253	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
707183001254	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707183001255	S-adenosylmethionine binding site [chemical binding]; other site
707183001256	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
707183001257	Lumazine binding domain; Region: Lum_binding; pfam00677
707183001258	Lumazine binding domain; Region: Lum_binding; pfam00677
707183001259	Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains [Transcription]; Region: COG1327
707183001260	ATP cone domain; Region: ATP-cone; pfam03477
707183001261	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
707183001262	Lipoprotein signal peptidase [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: LspA; COG0597
707183001263	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
707183001264	amino acid carrier protein; Region: agcS; TIGR00835
707183001265	poly(A) polymerase; Region: pcnB; TIGR01942
707183001266	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
707183001267	active site
707183001268	NTP binding site [chemical binding]; other site
707183001269	metal binding triad [ion binding]; metal-binding site
707183001270	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
707183001271	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK01021
707183001272	Lipid A Biosynthesis N-terminal domain; Region: LAB_N; pfam07578
707183001273	Predicted membrane protein [Function unknown]; Region: COG3952
707183001274	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
707183001275	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707183001276	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707183001277	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707183001278	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707183001279	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707183001280	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707183001281	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707183001282	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707183001283	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
707183001284	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
707183001285	intersubunit interface [polypeptide binding]; other site
707183001286	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707183001287	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
707183001288	Walker A/P-loop; other site
707183001289	ATP binding site [chemical binding]; other site
707183001290	Q-loop/lid; other site
707183001291	ABC transporter signature motif; other site
707183001292	Walker B; other site
707183001293	D-loop; other site
707183001294	H-loop/switch region; other site
707183001295	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
707183001296	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
707183001297	ABC-ATPase subunit  interface; other site
707183001298	dimer interface [polypeptide binding]; other site
707183001299	putative PBP binding regions; other site
707183001300	GTPase CgtA; Reviewed; Region: obgE; PRK12299
707183001301	GTP1/OBG; Region: GTP1_OBG; pfam01018
707183001302	Obg GTPase; Region: Obg; cd01898
707183001303	G1 box; other site
707183001304	GTP/Mg2+ binding site [chemical binding]; other site
707183001305	Switch I region; other site
707183001306	G2 box; other site
707183001307	G3 box; other site
707183001308	Switch II region; other site
707183001309	G4 box; other site
707183001310	G5 box; other site
707183001311	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
707183001312	Ribosomal protein L21 [Translation, ribosomal structure and biogenesis]; Region: RplU; COG0261
707183001313	Uncharacterized conserved protein [Function unknown]; Region: COG2928
707183001314	Chlam_Verruc_Plancto small basic protein; Region: Chlam_Ver_rRNA; TIGR04137
707183001315	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG0319
707183001316	FOG: CBS domain [General function prediction only]; Region: COG0517
707183001317	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
707183001318	Transporter associated domain; Region: CorC_HlyC; smart01091
707183001319	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
707183001320	anti sigma factor interaction site; other site
707183001321	regulatory phosphorylation site [posttranslational modification]; other site
707183001322	Protein of unknown function (DUF3604); Region: DUF3604; pfam12228
707183001323	hypothetical protein; Provisional; Region: PRK05926
707183001324	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
707183001325	FeS/SAM binding site; other site
707183001326	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
707183001327	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
707183001328	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707183001329	S-adenosylmethionine binding site [chemical binding]; other site
707183001330	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
707183001331	Uncharacterized protein family (UPF0158); Region: UPF0158; pfam03682
707183001332	diaminopimelate epimerase; Region: DapF; TIGR00652
707183001333	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
707183001334	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
707183001335	ATP-dependent Clp protease proteolytic subunit; Reviewed; Region: PRK12553
707183001336	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
707183001337	oligomer interface [polypeptide binding]; other site
707183001338	active site residues [active]
707183001339	serine hydroxymethyltransferase; Provisional; Region: PRK13580
707183001340	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
707183001341	dimer interface [polypeptide binding]; other site
707183001342	active site
707183001343	glycine-pyridoxal phosphate binding site [chemical binding]; other site
707183001344	folate binding site [chemical binding]; other site
707183001345	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
707183001346	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
707183001347	active site
707183001348	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
707183001349	homotrimer interaction site [polypeptide binding]; other site
707183001350	zinc binding site [ion binding]; other site
707183001351	CDP-binding sites; other site
707183001352	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
707183001353	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
707183001354	FAD binding pocket [chemical binding]; other site
707183001355	conserved FAD binding motif [chemical binding]; other site
707183001356	phosphate binding motif [ion binding]; other site
707183001357	beta-alpha-beta structure motif; other site
707183001358	NAD binding pocket [chemical binding]; other site
707183001359	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
707183001360	elongation factor G; Reviewed; Region: PRK12739
707183001361	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
707183001362	G1 box; other site
707183001363	putative GEF interaction site [polypeptide binding]; other site
707183001364	GTP/Mg2+ binding site [chemical binding]; other site
707183001365	Switch I region; other site
707183001366	G2 box; other site
707183001367	G3 box; other site
707183001368	Switch II region; other site
707183001369	G4 box; other site
707183001370	G5 box; other site
707183001371	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
707183001372	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
707183001373	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
707183001374	30S ribosomal protein S7; Validated; Region: PRK05302
707183001375	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
707183001376	S17 interaction site [polypeptide binding]; other site
707183001377	S8 interaction site; other site
707183001378	16S rRNA interaction site [nucleotide binding]; other site
707183001379	streptomycin interaction site [chemical binding]; other site
707183001380	23S rRNA interaction site [nucleotide binding]; other site
707183001381	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
707183001382	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
707183001383	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
707183001384	protein binding site [polypeptide binding]; other site
707183001385	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
707183001386	Catalytic dyad [active]
707183001387	Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA); Region: CRPA; pfam05745
707183001388	Chlamydia cysteine-rich outer membrane protein 6; Region: Chlam_OMP6; pfam03504
707183001389	Domain of unknown function DUF11; Region: DUF11; pfam01345
707183001390	Domain of unknown function DUF11; Region: DUF11; pfam01345
707183001391	Chlamydia cysteine-rich outer membrane protein 3; Region: Chlam_OMP3; pfam03503
707183001392	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
707183001393	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
707183001394	HIGH motif; other site
707183001395	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
707183001396	active site
707183001397	KMSKS motif; other site
707183001398	Helix-turn-helix domain; Region: HTH_17; pfam12728
707183001399	Helix-turn-helix domain; Region: HTH_17; pfam12728
707183001400	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
707183001401	DHH family; Region: DHH; pfam01368
707183001402	DHHA1 domain; Region: DHHA1; pfam02272
707183001403	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK12911
707183001404	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
707183001405	Protein export membrane protein; Region: SecD_SecF; pfam02355
707183001406	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14840
707183001407	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
707183001408	catalytic residue [active]
707183001409	putative FPP diphosphate  binding site; other site
707183001410	putative FPP binding hydrophobic cleft; other site
707183001411	dimer interface [polypeptide binding]; other site
707183001412	putative IPP diphosphate binding site; other site
707183001413	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
707183001414	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
707183001415	Cytidylate kinase [Nucleotide transport and metabolism]; Region: Cmk; COG0283
707183001416	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
707183001417	CMP-binding site; other site
707183001418	The sites determining sugar specificity; other site
707183001419	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
707183001420	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
707183001421	putative acyl-acceptor binding pocket; other site
707183001422	arginine-tRNA ligase; Region: PLN02286
707183001423	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
707183001424	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
707183001425	active site
707183001426	HIGH motif; other site
707183001427	KMSK motif region; other site
707183001428	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
707183001429	tRNA binding surface [nucleotide binding]; other site
707183001430	anticodon binding site; other site
707183001431	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
707183001432	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
707183001433	hinge; other site
707183001434	active site
707183001435	Domain of Unknown Function (DUF1547); Region: DUF1547; pfam07577
707183001436	Domain of Unknown Function (DUF1547); Region: DUF1547; pfam07577
707183001437	Domain of Unknown Function (DUF1547); Region: DUF1547; pfam07577
707183001438	DNA-binding regulatory protein, YebC/PmpR family; Region: TIGR01033
707183001439	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
707183001440	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
707183001441	Coenzyme A binding pocket [chemical binding]; other site
707183001442	PCRF domain; Region: PCRF; pfam03462
707183001443	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
707183001444	RF-1 domain; Region: RF-1; pfam00472
707183001445	SWIB-domain-containing proteins implicated in chromatin remodeling [Chromatin structure and dynamics]; Region: COG5531
707183001446	SWI complex, BAF60b domains; Region: SWIB; smart00151
707183001447	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
707183001448	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
707183001449	putative active site [active]
707183001450	putative metal binding site [ion binding]; other site
707183001451	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
707183001452	substrate binding site; other site
707183001453	dimer interface; other site
707183001454	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
707183001455	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
707183001456	dimerization interface 3.5A [polypeptide binding]; other site
707183001457	active site
707183001458	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
707183001459	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
707183001460	active site
707183001461	motif I; other site
707183001462	motif II; other site
707183001463	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
707183001464	PAS domain; Region: PAS; smart00091
707183001465	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
707183001466	dimer interface [polypeptide binding]; other site
707183001467	phosphorylation site [posttranslational modification]
707183001468	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707183001469	ATP binding site [chemical binding]; other site
707183001470	Mg2+ binding site [ion binding]; other site
707183001471	G-X-G motif; other site
707183001472	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
707183001473	Response regulator receiver domain; Region: Response_reg; pfam00072
707183001474	active site
707183001475	phosphorylation site [posttranslational modification]
707183001476	intermolecular recognition site; other site
707183001477	dimerization interface [polypeptide binding]; other site
707183001478	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183001479	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
707183001480	Walker A motif; other site
707183001481	ATP binding site [chemical binding]; other site
707183001482	Walker B motif; other site
707183001483	arginine finger; other site
707183001484	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
707183001485	Recombination protein O N terminal; Region: RecO_N; pfam11967
707183001486	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecO; COG1381
707183001487	Recombination protein O C terminal; Region: RecO_C; pfam02565
707183001488	potential protein location (hypothetical protein E11023_02475 [Chlamydia trachomatis E/11023]) that overlaps RNA (tRNA-L)
707183001489	Uncharacterized conserved protein [Function unknown]; Region: COG1723
707183001490	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
707183001491	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
707183001492	putative tRNA-binding site [nucleotide binding]; other site
707183001493	B3/4 domain; Region: B3_4; pfam03483
707183001494	tRNA synthetase B5 domain; Region: B5; smart00874
707183001495	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
707183001496	dimer interface [polypeptide binding]; other site
707183001497	motif 1; other site
707183001498	motif 3; other site
707183001499	motif 2; other site
707183001500	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
707183001501	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
707183001502	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
707183001503	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
707183001504	DNA binding site [nucleotide binding]
707183001505	active site
707183001506	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
707183001507	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707183001508	dimer interface [polypeptide binding]; other site
707183001509	conserved gate region; other site
707183001510	putative PBP binding loops; other site
707183001511	ABC-ATPase subunit interface; other site
707183001512	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
707183001513	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
707183001514	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
707183001515	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
707183001516	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
707183001517	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
707183001518	putative active site [active]
707183001519	putative metal binding site [ion binding]; other site
707183001520	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707183001521	binding surface
707183001522	TPR motif; other site
707183001523	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
707183001524	Protoheme ferro-lyase (ferrochelatase) [Coenzyme metabolism]; Region: HemH; COG0276
707183001525	C-terminal domain interface [polypeptide binding]; other site
707183001526	active site
707183001527	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
707183001528	active site
707183001529	N-terminal domain interface [polypeptide binding]; other site
707183001530	ABC-type amino acid transport/signal transduction systems, periplasmic component/domain [Amino acid transport and metabolism / Signal transduction mechanisms]; Region: HisJ; COG0834
707183001531	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
707183001532	substrate binding pocket [chemical binding]; other site
707183001533	membrane-bound complex binding site; other site
707183001534	hinge residues; other site
707183001535	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
707183001536	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707183001537	S-adenosylmethionine binding site [chemical binding]; other site
707183001538	Predicted phosphohydrolase [General function prediction only]; Region: COG1768
707183001539	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
707183001540	ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Region: GlgC; COG0448
707183001541	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
707183001542	ligand binding site; other site
707183001543	oligomer interface; other site
707183001544	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
707183001545	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
707183001546	N-terminal domain interface [polypeptide binding]; other site
707183001547	sulfate 1 binding site; other site
707183001548	transcription termination factor Rho; Region: rho; TIGR00767
707183001549	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
707183001550	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
707183001551	RNA binding site [nucleotide binding]; other site
707183001552	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
707183001553	multimer interface [polypeptide binding]; other site
707183001554	Walker A motif; other site
707183001555	ATP binding site [chemical binding]; other site
707183001556	Walker B motif; other site
707183001557	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
707183001558	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
707183001559	CoA-binding site [chemical binding]; other site
707183001560	ATP-binding [chemical binding]; other site
707183001561	DNA polymerase I; Provisional; Region: PRK05755
707183001562	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
707183001563	active site
707183001564	metal binding site 1 [ion binding]; metal-binding site
707183001565	putative 5' ssDNA interaction site; other site
707183001566	metal binding site 3; metal-binding site
707183001567	metal binding site 2 [ion binding]; metal-binding site
707183001568	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
707183001569	putative DNA binding site [nucleotide binding]; other site
707183001570	putative metal binding site [ion binding]; other site
707183001571	3'-5' exonuclease; Region: 35EXOc; smart00474
707183001572	active site
707183001573	substrate binding site [chemical binding]; other site
707183001574	catalytic site [active]
707183001575	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
707183001576	active site
707183001577	DNA binding site [nucleotide binding]
707183001578	catalytic site [active]
707183001579	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
707183001580	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
707183001581	tandem repeat interface [polypeptide binding]; other site
707183001582	oligomer interface [polypeptide binding]; other site
707183001583	active site residues [active]
707183001584	TLC ATP/ADP transporter; Region: TLC; pfam03219
707183001585	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
707183001586	replicative DNA helicase; Provisional; Region: PRK06321
707183001587	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
707183001588	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
707183001589	Walker A motif; other site
707183001590	ATP binding site [chemical binding]; other site
707183001591	Walker B motif; other site
707183001592	DNA binding loops [nucleotide binding]
707183001593	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
707183001594	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
707183001595	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
707183001596	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
707183001597	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
707183001598	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
707183001599	active site
707183001600	multimer interface [polypeptide binding]; other site
707183001601	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
707183001602	RuvA N terminal domain; Region: RuvA_N; pfam01330
707183001603	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
707183001604	active site
707183001605	putative DNA-binding cleft [nucleotide binding]; other site
707183001606	dimer interface [polypeptide binding]; other site
707183001607	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
707183001608	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
707183001609	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
707183001610	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
707183001611	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
707183001612	DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; Region: rpoA; TIGR02027
707183001613	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
707183001614	alphaNTD - beta interaction site [polypeptide binding]; other site
707183001615	alphaNTD homodimer interface [polypeptide binding]; other site
707183001616	alphaNTD - beta' interaction site [polypeptide binding]; other site
707183001617	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
707183001618	30S ribosomal protein S11; Validated; Region: PRK05309
707183001619	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
707183001620	30S ribosomal protein S13; Region: bact_S13; TIGR03631
707183001621	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
707183001622	SecY translocase; Region: SecY; pfam00344
707183001623	ribosomal protein L15, bacterial/organelle; Region: rplO_bact; TIGR01071
707183001624	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
707183001625	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
707183001626	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
707183001627	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
707183001628	5S rRNA interface [nucleotide binding]; other site
707183001629	23S rRNA interface [nucleotide binding]; other site
707183001630	L5 interface [polypeptide binding]; other site
707183001631	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
707183001632	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
707183001633	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
707183001634	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
707183001635	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
707183001636	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
707183001637	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
707183001638	Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Region: RplX; COG0198
707183001639	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
707183001640	RNA binding site [nucleotide binding]; other site
707183001641	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
707183001642	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
707183001643	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
707183001644	23S rRNA interface [nucleotide binding]; other site
707183001645	putative translocon interaction site; other site
707183001646	signal recognition particle (SRP54) interaction site; other site
707183001647	L23 interface [polypeptide binding]; other site
707183001648	trigger factor interaction site; other site
707183001649	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
707183001650	23S rRNA interface [nucleotide binding]; other site
707183001651	5S rRNA interface [nucleotide binding]; other site
707183001652	putative antibiotic binding site [chemical binding]; other site
707183001653	L25 interface [polypeptide binding]; other site
707183001654	L27 interface [polypeptide binding]; other site
707183001655	ribosomal protein S3, bacterial type; Region: rpsC_bact; TIGR01009
707183001656	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
707183001657	G-X-X-G motif; other site
707183001658	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
707183001659	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
707183001660	putative translocon binding site; other site
707183001661	protein-rRNA interface [nucleotide binding]; other site
707183001662	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
707183001663	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
707183001664	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
707183001665	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
707183001666	Ribosomal protein L23 [Translation, ribosomal structure and biogenesis]; Region: RplW; COG0089
707183001667	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
707183001668	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
707183001669	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
707183001670	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
707183001671	putative active site [active]
707183001672	substrate binding site [chemical binding]; other site
707183001673	putative cosubstrate binding site; other site
707183001674	catalytic site [active]
707183001675	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
707183001676	substrate binding site [chemical binding]; other site
707183001677	Acyl-[acyl carrier protein]; Region: LpxA; COG1043
707183001678	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
707183001679	active site
707183001680	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
707183001681	UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell envelope biogenesis, outer membrane]; Region: LpxC; COG0774
707183001682	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
707183001683	Apolipoprotein N-acyltransferase [Cell envelope biogenesis, outer membrane]; Region: Lnt; COG0815
707183001684	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
707183001685	putative active site [active]
707183001686	catalytic triad [active]
707183001687	putative dimer interface [polypeptide binding]; other site
707183001688	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
707183001689	DNA polymerase III subunit epsilon; Validated; Region: PRK06310
707183001690	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
707183001691	active site
707183001692	catalytic site [active]
707183001693	substrate binding site [chemical binding]; other site
707183001694	Protein of unknown function (DUF3820); Region: DUF3820; cl01411
707183001695	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; pfam02367
707183001696	Protein of unknown function (DUF2709); Region: DUF2709; pfam10915
707183001697	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
707183001698	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
707183001699	catalytic residues [active]
707183001700	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
707183001701	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
707183001702	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
707183001703	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
707183001704	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
707183001705	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
707183001706	dimer interface [polypeptide binding]; other site
707183001707	anticodon binding site; other site
707183001708	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
707183001709	homodimer interface [polypeptide binding]; other site
707183001710	motif 1; other site
707183001711	active site
707183001712	motif 2; other site
707183001713	GAD domain; Region: GAD; pfam02938
707183001714	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
707183001715	active site
707183001716	motif 3; other site
707183001717	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
707183001718	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
707183001719	dimer interface [polypeptide binding]; other site
707183001720	motif 1; other site
707183001721	active site
707183001722	motif 2; other site
707183001723	motif 3; other site
707183001724	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
707183001725	anticodon binding site; other site
707183001726	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
707183001727	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707183001728	putative substrate translocation pore; other site
707183001729	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707183001730	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
707183001731	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
707183001732	active site
707183001733	PHP Thumb interface [polypeptide binding]; other site
707183001734	metal binding site [ion binding]; metal-binding site
707183001735	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
707183001736	generic binding surface I; other site
707183001737	generic binding surface II; other site
707183001738	TPR repeat; Region: TPR_11; pfam13414
707183001739	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707183001740	binding surface
707183001741	TPR motif; other site
707183001742	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
707183001743	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
707183001744	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
707183001745	Mg2+ binding site [ion binding]; other site
707183001746	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
707183001747	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
707183001748	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
707183001749	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707183001750	S-adenosylmethionine binding site [chemical binding]; other site
707183001751	branched-chain amino acid uptake carrier; Region: livcs; TIGR00796
707183001752	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
707183001753	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707183001754	ATP binding site [chemical binding]; other site
707183001755	putative Mg++ binding site [ion binding]; other site
707183001756	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707183001757	ATP-binding site [chemical binding]; other site
707183001758	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
707183001759	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
707183001760	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
707183001761	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
707183001762	lipoate synthase; Region: lipA; TIGR00510
707183001763	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
707183001764	FeS/SAM binding site; other site
707183001765	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
707183001766	type III secretion system protein; Validated; Region: PRK06328
707183001767	Flagellar assembly protein FliH; Region: FliH; pfam02108
707183001768	type III secretion system protein; Reviewed; Region: PRK09617
707183001769	Type III secretory pathway, component EscS [Intracellular trafficking and secretion]; Region: EscS; COG4794
707183001770	Type III secretory pathway, component EscT [Intracellular trafficking and secretion]; Region: EscT; COG4791
707183001771	Protein of unknown function (DUF1494); Region: DUF1494; pfam07379
707183001772	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
707183001773	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
707183001774	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
707183001775	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
707183001776	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
707183001777	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
707183001778	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
707183001779	Walker A motif; other site
707183001780	ATP binding site [chemical binding]; other site
707183001781	Walker B motif; other site
707183001782	Type II secretory pathway, component PulD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulD; COG1450
707183001783	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
707183001784	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
707183001785	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
707183001786	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
707183001787	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
707183001788	active site
707183001789	DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair]; Region: MutL; COG0323
707183001790	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707183001791	ATP binding site [chemical binding]; other site
707183001792	Mg2+ binding site [ion binding]; other site
707183001793	G-X-G motif; other site
707183001794	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
707183001795	ATP binding site [chemical binding]; other site
707183001796	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
707183001797	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
707183001798	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707183001799	binding surface
707183001800	TPR motif; other site
707183001801	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
707183001802	EamA-like transporter family; Region: EamA; pfam00892
707183001803	EamA-like transporter family; Region: EamA; pfam00892
707183001804	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
707183001805	The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information...; Region: TGS; cd01616
707183001806	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
707183001807	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
707183001808	active site
707183001809	dimer interface [polypeptide binding]; other site
707183001810	motif 1; other site
707183001811	motif 2; other site
707183001812	motif 3; other site
707183001813	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
707183001814	anticodon binding site; other site
707183001815	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
707183001816	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
707183001817	Uncharacterized protein family (UPF0137); Region: UPF0137; pfam03677
707183001818	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
707183001819	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
707183001820	active site
707183001821	HIGH motif; other site
707183001822	dimer interface [polypeptide binding]; other site
707183001823	KMSKS motif; other site
707183001824	excinuclease ABC subunit B; Provisional; Region: PRK05298
707183001825	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707183001826	ATP binding site [chemical binding]; other site
707183001827	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707183001828	nucleotide binding region [chemical binding]; other site
707183001829	ATP-binding site [chemical binding]; other site
707183001830	Ultra-violet resistance protein B; Region: UvrB; pfam12344
707183001831	enolase; Provisional; Region: eno; PRK00077
707183001832	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
707183001833	dimer interface [polypeptide binding]; other site
707183001834	metal binding site [ion binding]; metal-binding site
707183001835	substrate binding pocket [chemical binding]; other site
707183001836	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
707183001837	HAMP domain; Region: HAMP; pfam00672
707183001838	dimerization interface [polypeptide binding]; other site
707183001839	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
707183001840	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
707183001841	Sigma factor PP2C-like phosphatases; Region: PP2C_SIG; smart00331
707183001842	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK08640
707183001843	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
707183001844	potential frameshift: common BLAST hit: gi|237803021|ref|YP_002888215.1| succinate dehydrogenase flavoprotein subunit
707183001845	Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, transmembrane subunits; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol, while QFR catalyzes the reverse reaction. SQR; Region: SQR_QFR_TM; cl00881
707183001846	Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, transmembrane subunits; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol, while QFR catalyzes the reverse reaction. SQR; Region: SQR_QFR_TM; cl00881
707183001847	proximal heme binding site [chemical binding]; other site
707183001848	Iron-sulfur protein interface; other site
707183001849	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
707183001850	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
707183001851	active site
707183001852	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
707183001853	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
707183001854	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
707183001855	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
707183001856	DsbD alpha interface [polypeptide binding]; other site
707183001857	catalytic residues [active]
707183001858	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
707183001859	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
707183001860	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
707183001861	translocation protein TolB; Provisional; Region: tolB; PRK01029
707183001862	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
707183001863	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
707183001864	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
707183001865	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
707183001866	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
707183001867	ligand binding site [chemical binding]; other site
707183001868	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
707183001869	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
707183001870	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
707183001871	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
707183001872	dimer interface [polypeptide binding]; other site
707183001873	decamer (pentamer of dimers) interface [polypeptide binding]; other site
707183001874	catalytic triad [active]
707183001875	peroxidatic and resolving cysteines [active]
707183001876	Chaperonin GroEL (HSP60 family) [Posttranslational modification, protein turnover, chaperones]; Region: GroL; COG0459
707183001877	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
707183001878	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3876
707183001879	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
707183001880	active site
707183001881	dimerization interface [polypeptide binding]; other site
707183001882	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
707183001883	ligand binding site [chemical binding]; other site
707183001884	active site
707183001885	UGI interface [polypeptide binding]; other site
707183001886	catalytic site [active]
707183001887	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
707183001888	Part of AAA domain; Region: AAA_19; pfam13245
707183001889	Family description; Region: UvrD_C_2; pfam13538
707183001890	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog [Transcription]; Region: RpoN; COG1508
707183001891	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
707183001892	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
707183001893	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
707183001894	Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C [Coenzyme metabolism]; Region: COG5424
707183001895	GTP and metal dependent enzyme involved F420 coenzyme biosynthesis (catalyzes addition of two l-glutamates to F420 precursor) [Coenzyme transport and metabolism]; Region: COG1478
707183001896	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; cl00644
707183001897	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
707183001898	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
707183001899	folate binding site [chemical binding]; other site
707183001900	NADP+ binding site [chemical binding]; other site
707183001901	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
707183001902	catalytic center binding site [active]
707183001903	ATP binding site [chemical binding]; other site
707183001904	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
707183001905	dihydropteroate synthase; Region: DHPS; TIGR01496
707183001906	substrate binding pocket [chemical binding]; other site
707183001907	dimer interface [polypeptide binding]; other site
707183001908	inhibitor binding site; inhibition site
707183001909	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
707183001910	homooctamer interface [polypeptide binding]; other site
707183001911	active site
707183001912	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
707183001913	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
707183001914	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
707183001915	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
707183001916	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
707183001917	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
707183001918	DNA binding residues [nucleotide binding]
707183001919	Uncharacterized protein family (UPF0242); Region: UPF0242; pfam06785
707183001920	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
707183001921	Effector from type III secretion system; Region: Effector_1; pfam04518
707183001922	Effector from type III secretion system; Region: Effector_1; pfam04518
707183001923	Effector from type III secretion system; Region: Effector_1; pfam04518
707183001924	Exodeoxyribonuclease V, gamma subunit; Region: Exonuc_V_gamma; pfam04257
707183001925	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
707183001926	MviN-like protein; Region: MVIN; pfam03023
707183001927	endonuclease IV; Provisional; Region: PRK01060
707183001928	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
707183001929	AP (apurinic/apyrimidinic) site pocket; other site
707183001930	DNA interaction; other site
707183001931	Metal-binding active site; metal-binding site
707183001932	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
707183001933	ribosomal protein S4, bacterial/organelle type; Region: rpsD_bact; TIGR01017
707183001934	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707183001935	RNA binding surface [nucleotide binding]; other site
707183001936	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
707183001937	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
707183001938	active site residue [active]
707183001939	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
707183001940	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
707183001941	substrate binding pocket [chemical binding]; other site
707183001942	chain length determination region; other site
707183001943	substrate-Mg2+ binding site; other site
707183001944	catalytic residues [active]
707183001945	aspartate-rich region 1; other site
707183001946	active site lid residues [active]
707183001947	aspartate-rich region 2; other site
707183001948	Putative glucose-1-phosphate thymidylyltransferase, C-terminal Left-handed parallel beta-Helix (LbH) domain: Proteins in this family show simlarity to glucose-1-phosphate adenylyltransferases in that they contain N-terminal catalytic domains that...; Region: LbH_G1P_TT_C_like; cd05636
707183001949	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
707183001950	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
707183001951	DNA binding site [nucleotide binding]
707183001952	Predicted alternative thymidylate synthase [Nucleotide transport and metabolism]; Region: THY1; COG1351
707183001953	Thymidylate synthase complementing protein; Region: Thy1; cl03630
707183001954	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
707183001955	dimer interface [polypeptide binding]; other site
707183001956	active site
707183001957	aspartate-rich active site metal binding site; other site
707183001958	allosteric magnesium binding site [ion binding]; other site
707183001959	Schiff base residues; other site
707183001960	NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit; Region: nqrA; TIGR01936
707183001961	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
707183001962	lipoyl-biotinyl attachment site [posttranslational modification]; other site
707183001963	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
707183001964	Putative bacteriophage terminase small subunit; Region: Phage_term_sma; pfam07141
707183001965	transcript cleavage factor/unknown domain fusion protein; Validated; Region: PRK06330
707183001966	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
707183001967	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
707183001968	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
707183001969	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
707183001970	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707183001971	homodimer interface [polypeptide binding]; other site
707183001972	catalytic residue [active]
707183001973	rod shape-determining protein MreC; Provisional; Region: PRK14872
707183001974	rod shape-determining protein MreC; Region: MreC; pfam04085
707183001975	exodeoxyribonuclease V, beta subunit; Region: recB; TIGR00609
707183001976	Part of AAA domain; Region: AAA_19; pfam13245
707183001977	Family description; Region: UvrD_C_2; pfam13538
707183001978	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
707183001979	Major Facilitator Superfamily; Region: MFS_1; pfam07690
707183001980	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707183001981	putative substrate translocation pore; other site
707183001982	DNA topoisomerase I/SWI domain fusion protein; Validated; Region: PRK06319
707183001983	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
707183001984	active site
707183001985	interdomain interaction site; other site
707183001986	putative metal-binding site [ion binding]; other site
707183001987	nucleotide binding site [chemical binding]; other site
707183001988	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
707183001989	domain I; other site
707183001990	DNA binding groove [nucleotide binding]
707183001991	phosphate binding site [ion binding]; other site
707183001992	domain II; other site
707183001993	domain III; other site
707183001994	nucleotide binding site [chemical binding]; other site
707183001995	catalytic site [active]
707183001996	domain IV; other site
707183001997	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
707183001998	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
707183001999	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
707183002000	SWI complex, BAF60b domains; Region: SWIB; smart00151
707183002001	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
707183002002	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
707183002003	FMN binding site [chemical binding]; other site
707183002004	active site
707183002005	catalytic residues [active]
707183002006	substrate binding site [chemical binding]; other site
707183002007	Predicted integral membrane protein [Function unknown]; Region: COG0762
707183002008	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
707183002009	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
707183002010	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
707183002011	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
707183002012	recombinase A; Provisional; Region: recA; PRK09354
707183002013	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
707183002014	hexamer interface [polypeptide binding]; other site
707183002015	Walker A motif; other site
707183002016	ATP binding site [chemical binding]; other site
707183002017	Walker B motif; other site
707183002018	Protein of unknown function (DUF1347); Region: DUF1347; pfam07079
707183002019	exodeoxyribonuclease V, alpha subunit; Region: recD; TIGR01447
707183002020	AAA domain; Region: AAA_30; pfam13604
707183002021	Family description; Region: UvrD_C_2; pfam13538
707183002022	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
707183002023	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
707183002024	Walker A/P-loop; other site
707183002025	ATP binding site [chemical binding]; other site
707183002026	Q-loop/lid; other site
707183002027	ABC transporter signature motif; other site
707183002028	Walker B; other site
707183002029	D-loop; other site
707183002030	H-loop/switch region; other site
707183002031	Protein of unknown function (DUF1137); Region: DUF1137; pfam06587
707183002032	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
707183002033	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
707183002034	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
707183002035	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707183002036	RNA binding surface [nucleotide binding]; other site
707183002037	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
707183002038	active site
707183002039	hypothetical protein; Provisional; Region: PRK01064
707183002040	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
707183002041	DNA topoisomerase IV subunit A; Provisional; Region: PRK09630
707183002042	DNA Topoisomerase IV; Region: TOP4c; smart00434
707183002043	CAP-like domain; other site
707183002044	active site
707183002045	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
707183002046	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707183002047	ATP binding site [chemical binding]; other site
707183002048	Mg2+ binding site [ion binding]; other site
707183002049	G-X-G motif; other site
707183002050	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of type II DNA topoisomerases (Topo II) and DNA mismatch repair (MutL/MLH1/PMS2) proteins. This transducer domain is homologous to the second...; Region: TopoII_MutL_Trans; cl02783
707183002051	ATP binding site [chemical binding]; other site
707183002052	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
707183002053	active site
707183002054	putative metal-binding site [ion binding]; other site
707183002055	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
707183002056	glutamyl-tRNA reductase; Validated; Region: hemA; PRK00676
707183002057	Glutamyl-tRNAGlu reductase, N-terminal domain; Region: GlutR_N; pfam05201
707183002058	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
707183002059	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
707183002060	phosphopeptide binding site; other site
707183002061	MARCKS family; Region: MARCKS; pfam02063
707183002062	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
707183002063	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
707183002064	phosphopeptide binding site; other site
707183002065	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
707183002066	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
707183002067	binding surface
707183002068	Tetratricopeptide repeat; Region: TPR_16; pfam13432
707183002069	TPR motif; other site
707183002070	type III secretion system ATPase; Provisional; Region: PRK06315
707183002071	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707183002072	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
707183002073	Walker A motif/ATP binding site; other site
707183002074	Walker B motif; other site
707183002075	type III secretion system protein; Validated; Region: PRK05933
707183002076	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
707183002077	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
707183002078	Catalytic domain of Protein Kinases; Region: PKc; cd00180
707183002079	active site
707183002080	ATP binding site [chemical binding]; other site
707183002081	substrate binding site [chemical binding]; other site
707183002082	activation loop (A-loop); other site
707183002083	Type II secretory pathway, component PulD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulD; COG1450
707183002084	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
707183002085	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
707183002086	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
707183002087	Arginine kinase [Amino acid transport and metabolism]; Region: COG3869
707183002088	Phosphagen (guanidino) kinases; Region: phosphagen_kinases; cl02823
707183002089	ADP binding site [chemical binding]; other site
707183002090	phosphagen binding site; other site
707183002091	substrate specificity loop; other site
707183002092	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
707183002093	UvrB/uvrC motif; Region: UVR; pfam02151
707183002094	ribosome recycling factor; Reviewed; Region: frr; PRK00083
707183002095	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
707183002096	hinge region; other site
707183002097	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
707183002098	putative nucleotide binding site [chemical binding]; other site
707183002099	uridine monophosphate binding site [chemical binding]; other site
707183002100	homohexameric interface [polypeptide binding]; other site
707183002101	Translation elongation factor Ts [Translation, ribosomal structure and biogenesis]; Region: Tsf; COG0264
707183002102	Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; Region: UBA; cl00153
707183002103	Elongation factor TS; Region: EF_TS; pfam00889
707183002104	Elongation factor TS; Region: EF_TS; pfam00889
707183002105	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
707183002106	rRNA interaction site [nucleotide binding]; other site
707183002107	S8 interaction site; other site
707183002108	putative laminin-1 binding site; other site
707183002109	Chlamydia major outer membrane protein; Region: Chlam_OMP; pfam01308
707183002110	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
707183002111	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
707183002112	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
707183002113	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
707183002114	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707183002115	TPR motif; other site
707183002116	Tetratricopeptide repeat; Region: TPR_16; pfam13432
707183002117	binding surface
707183002118	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707183002119	binding surface
707183002120	TPR motif; other site
707183002121	TPR repeat; Region: TPR_11; pfam13414
707183002122	TPR repeat; Region: TPR_11; pfam13414
707183002123	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707183002124	binding surface
707183002125	TPR motif; other site
707183002126	TPR repeat; Region: TPR_11; pfam13414
707183002127	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
707183002128	putative ABC transporter; Region: ycf24; CHL00085
707183002129	FeS assembly ATPase SufC; Region: sufC; TIGR01978
707183002130	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
707183002131	Walker A/P-loop; other site
707183002132	ATP binding site [chemical binding]; other site
707183002133	Q-loop/lid; other site
707183002134	ABC transporter signature motif; other site
707183002135	Walker B; other site
707183002136	D-loop; other site
707183002137	H-loop/switch region; other site
707183002138	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
707183002139	FeS assembly protein SufD; Region: sufD; TIGR01981
707183002140	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
707183002141	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
707183002142	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707183002143	catalytic residue [active]
707183002144	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
707183002145	ParB-like nuclease domain; Region: ParBc; pfam02195
707183002146	KorB domain; Region: KorB; pfam08535
707183002147	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707183002148	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
707183002149	Walker A/P-loop; other site
707183002150	ATP binding site [chemical binding]; other site
707183002151	Q-loop/lid; other site
707183002152	ABC transporter signature motif; other site
707183002153	Walker B; other site
707183002154	D-loop; other site
707183002155	H-loop/switch region; other site
707183002156	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
707183002157	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
707183002158	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707183002159	Walker A/P-loop; other site
707183002160	ATP binding site [chemical binding]; other site
707183002161	Q-loop/lid; other site
707183002162	ABC transporter signature motif; other site
707183002163	Walker B; other site
707183002164	D-loop; other site
707183002165	H-loop/switch region; other site
707183002166	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
707183002167	Protein of unknown function DUF47; Region: PhoU_div; pfam01865
707183002168	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
707183002169	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
707183002170	Phosphoglycerate kinase; Region: PGK; pfam00162
707183002171	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
707183002172	substrate binding site [chemical binding]; other site
707183002173	hinge regions; other site
707183002174	ADP binding site [chemical binding]; other site
707183002175	catalytic site [active]
707183002176	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
707183002177	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
707183002178	minor groove reading motif; other site
707183002179	helix-hairpin-helix signature motif; other site
707183002180	substrate binding pocket [chemical binding]; other site
707183002181	active site
707183002182	Predicted GTPase [General function prediction only]; Region: ThdF; COG0486
707183002183	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
707183002184	trmE is a tRNA modification GTPase; Region: trmE; cd04164
707183002185	G1 box; other site
707183002186	GTP/Mg2+ binding site [chemical binding]; other site
707183002187	Switch I region; other site
707183002188	G2 box; other site
707183002189	Switch II region; other site
707183002190	G3 box; other site
707183002191	G4 box; other site
707183002192	G5 box; other site
707183002193	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
707183002194	phosphatidylserine decarboxylase; Provisional; Region: PRK00723
707183002195	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707183002196	binding surface
707183002197	TPR motif; other site
707183002198	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12899
707183002199	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
707183002200	ATP binding site [chemical binding]; other site
707183002201	putative Mg++ binding site [ion binding]; other site
707183002202	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
707183002203	Predicted GTPases [General function prediction only]; Region: COG1160
707183002204	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
707183002205	G1 box; other site
707183002206	GTP/Mg2+ binding site [chemical binding]; other site
707183002207	Switch I region; other site
707183002208	G2 box; other site
707183002209	Switch II region; other site
707183002210	G3 box; other site
707183002211	G4 box; other site
707183002212	G5 box; other site
707183002213	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
707183002214	G1 box; other site
707183002215	GTP/Mg2+ binding site [chemical binding]; other site
707183002216	Switch I region; other site
707183002217	G2 box; other site
707183002218	G3 box; other site
707183002219	Switch II region; other site
707183002220	G4 box; other site
707183002221	G5 box; other site
707183002222	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
707183002223	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
707183002224	active site
707183002225	NTP binding site [chemical binding]; other site
707183002226	metal binding triad [ion binding]; metal-binding site
707183002227	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
707183002228	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
707183002229	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
707183002230	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183002231	Walker A motif; other site
707183002232	ATP binding site [chemical binding]; other site
707183002233	Walker B motif; other site
707183002234	arginine finger; other site
707183002235	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
707183002236	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
707183002237	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
707183002238	oligomer interface [polypeptide binding]; other site
707183002239	active site residues [active]
707183002240	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) [Posttranslational modification, protein turnover, chaperones]; Region: Tig; COG0544
707183002241	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
707183002242	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
707183002243	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
707183002244	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707183002245	ATP binding site [chemical binding]; other site
707183002246	putative Mg++ binding site [ion binding]; other site
707183002247	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707183002248	nucleotide binding region [chemical binding]; other site
707183002249	ATP-binding site [chemical binding]; other site
707183002250	rod shape-determining protein MreB; Provisional; Region: PRK13927
707183002251	MreB and similar proteins; Region: MreB_like; cd10225
707183002252	nucleotide binding site [chemical binding]; other site
707183002253	Mg binding site [ion binding]; other site
707183002254	putative protofilament interaction site [polypeptide binding]; other site
707183002255	RodZ interaction site [polypeptide binding]; other site
707183002256	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819
707183002257	active site
707183002258	substrate-binding site [chemical binding]; other site
707183002259	metal-binding site [ion binding]
707183002260	GTP binding site [chemical binding]; other site
707183002261	Effector from type III secretion system; Region: Effector_1; pfam04518
707183002262	Effector from type III secretion system; Region: Effector_1; pfam04518
707183002263	Chlamydia major outer membrane protein; Region: Chlam_OMP; pfam01308
707183002264	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
707183002265	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
707183002266	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
707183002267	UDP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Region: COG4284
707183002268	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
707183002269	active site
707183002270	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
707183002271	type III secretion system ATPase; Validated; Region: PRK05922
707183002272	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707183002273	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
707183002274	Walker A motif; other site
707183002275	ATP binding site [chemical binding]; other site
707183002276	Walker B motif; other site
707183002277	type III secretion system protein; Validated; Region: PRK05934
707183002278	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
707183002279	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cl00528
707183002280	active site
707183002281	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
707183002282	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
707183002283	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707183002284	catalytic residue [active]
707183002285	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
707183002286	catalytic core [active]
707183002287	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
707183002288	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707183002289	RNA binding surface [nucleotide binding]; other site
707183002290	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
707183002291	active site
707183002292	biotin--protein ligase; Provisional; Region: PRK05935
707183002293	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
707183002294	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
707183002295	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
707183002296	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
707183002297	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
707183002298	motif II; other site
707183002299	CCC1-related protein family; Region: CCC1_like_1; cd02437
707183002300	seryl-tRNA synthetase; Provisional; Region: PRK05431
707183002301	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
707183002302	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
707183002303	dimer interface [polypeptide binding]; other site
707183002304	active site
707183002305	motif 1; other site
707183002306	motif 2; other site
707183002307	motif 3; other site
707183002308	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
707183002309	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
707183002310	catalytic motif [active]
707183002311	Zn binding site [ion binding]; other site
707183002312	RibD C-terminal domain; Region: RibD_C; pfam01872
707183002313	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
707183002314	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
707183002315	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
707183002316	dimerization interface [polypeptide binding]; other site
707183002317	active site
707183002318	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
707183002319	homopentamer interface [polypeptide binding]; other site
707183002320	active site
707183002321	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
707183002322	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
707183002323	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
707183002324	substrate binding site [chemical binding]; other site
707183002325	Proteins containing SET domain [General function prediction only]; Region: COG2940
707183002326	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; Region: SET; smart00317
707183002327	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
707183002328	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
707183002329	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
707183002330	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
707183002331	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
707183002332	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF [Energy production and conversion]; Region: NqrF; COG2871
707183002333	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
707183002334	catalytic loop [active]
707183002335	iron binding site [ion binding]; other site
707183002336	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
707183002337	FAD binding pocket [chemical binding]; other site
707183002338	FAD binding motif [chemical binding]; other site
707183002339	phosphate binding motif [ion binding]; other site
707183002340	beta-alpha-beta structure motif; other site
707183002341	NAD binding pocket [chemical binding]; other site
707183002342	preprotein translocase, YajC subunit; Region: yajC; TIGR00739
707183002343	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
707183002344	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707183002345	S-adenosylmethionine binding site [chemical binding]; other site
707183002346	Histone H1-like protein Hc1; Region: Hc1; pfam07432
707183002347	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707183002348	binding surface
707183002349	TPR motif; other site
707183002350	Tetratricopeptide repeat; Region: TPR_12; pfam13424
707183002351	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
707183002352	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
707183002353	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
707183002354	HemN C-terminal domain; Region: HemN_C; pfam06969
707183002355	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
707183002356	substrate binding site [chemical binding]; other site
707183002357	active site
707183002358	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
707183002359	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
707183002360	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707183002361	ATP binding site [chemical binding]; other site
707183002362	putative Mg++ binding site [ion binding]; other site
707183002363	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707183002364	nucleotide binding region [chemical binding]; other site
707183002365	ATP-binding site [chemical binding]; other site
707183002366	TRCF domain; Region: TRCF; pfam03461
707183002367	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
707183002368	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
707183002369	motif 1; other site
707183002370	active site
707183002371	motif 2; other site
707183002372	motif 3; other site
707183002373	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
707183002374	DHHA1 domain; Region: DHHA1; pfam02272
707183002375	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
707183002376	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
707183002377	TPP-binding site [chemical binding]; other site
707183002378	dimer interface [polypeptide binding]; other site
707183002379	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
707183002380	PYR/PP interface [polypeptide binding]; other site
707183002381	dimer interface [polypeptide binding]; other site
707183002382	TPP binding site [chemical binding]; other site
707183002383	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707183002384	AMP nucleosidase, putative; Region: AMN-like; TIGR01721
707183002385	elongation factor P; Validated; Region: PRK00529
707183002386	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
707183002387	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
707183002388	RNA binding site [nucleotide binding]; other site
707183002389	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
707183002390	RNA binding site [nucleotide binding]; other site
707183002391	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
707183002392	Bacillus subtilis YydB and related proteins, metallophosphatase domain; Region: MPP_YydB; cd07400
707183002393	putative active site [active]
707183002394	putative metal binding site [ion binding]; other site
707183002395	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
707183002396	active site
707183002397	metal binding site [ion binding]; metal-binding site
707183002398	Chaperonin GroEL (HSP60 family) [Posttranslational modification, protein turnover, chaperones]; Region: GroL; COG0459
707183002399	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
707183002400	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
707183002401	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707183002402	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707183002403	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
707183002404	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
707183002405	Mg++ binding site [ion binding]; other site
707183002406	putative catalytic motif [active]
707183002407	putative substrate binding site [chemical binding]; other site
707183002408	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK00683
707183002409	TrkA-N domain; Region: TrkA_N; pfam02254
707183002410	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707183002411	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707183002412	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
707183002413	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
707183002414	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
707183002415	cell division protein FtsW; Region: ftsW; TIGR02614
707183002416	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
707183002417	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
707183002418	active site
707183002419	homodimer interface [polypeptide binding]; other site
707183002420	bifunctional D-alanyl-alanine synthetase A/UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: PRK14573
707183002421	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
707183002422	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707183002423	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707183002424	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
707183002425	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
707183002426	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
707183002427	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cd02409
707183002428	G-X-X-G motif; other site
707183002429	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
707183002430	anti sigma factor interaction site; other site
707183002431	regulatory phosphorylation site [posttranslational modification]; other site
707183002432	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
707183002433	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
707183002434	hypothetical protein; Provisional; Region: PRK05927
707183002435	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
707183002436	FeS/SAM binding site; other site
707183002437	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
707183002438	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
707183002439	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK06333
707183002440	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
707183002441	dimer interface [polypeptide binding]; other site
707183002442	active site
707183002443	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Ap4A hydrolases are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_human_like; cd03428
707183002444	active site
707183002445	Ap4A binding cleft/pocket [chemical binding]; other site
707183002446	P4 phosphate binding site; other site
707183002447	nudix motif; other site
707183002448	putative P2/P3 phosphate binding site [ion binding]; other site
707183002449	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
707183002450	dimer interface [polypeptide binding]; other site
707183002451	substrate binding site [chemical binding]; other site
707183002452	metal binding sites [ion binding]; metal-binding site
707183002453	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
707183002454	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
707183002455	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
707183002456	NAD binding site [chemical binding]; other site
707183002457	Phe binding site; other site
707183002458	PAP-phosphatase_like domains. PAP-phosphatase is a member of the inositol monophosphatase family, and catalyses the hydrolysis of 3'-phosphoadenosine-5'-phosphate (PAP) to AMP. In Saccharomyces cerevisiae, HAL2 (MET22) is involved in methionine...; Region: PAP_phosphatase; cd01517
707183002459	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
707183002460	active site
707183002461	putative lithium-binding site [ion binding]; other site
707183002462	substrate binding site [chemical binding]; other site
707183002463	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
707183002464	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
707183002465	putative acyl-acceptor binding pocket; other site
707183002466	long chain fatty acid--[acyl-carrier-protein] ligase; Validated; Region: PRK06334
707183002467	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
707183002468	acyl-activating enzyme (AAE) consensus motif; other site
707183002469	AMP binding site [chemical binding]; other site
707183002470	active site
707183002471	CoA binding site [chemical binding]; other site
707183002472	8-amino-7-oxononanoate synthase; Provisional; Region: PRK05937
707183002473	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
707183002474	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707183002475	catalytic residue [active]
707183002476	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
707183002477	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707183002478	ATP binding site [chemical binding]; other site
707183002479	putative Mg++ binding site [ion binding]; other site
707183002480	helicase superfamily c-terminal domain; Region: HELICc; smart00490
707183002481	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
707183002482	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
707183002483	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
707183002484	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
707183002485	dimer interface [polypeptide binding]; other site
707183002486	putative anticodon binding site; other site
707183002487	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
707183002488	motif 1; other site
707183002489	dimer interface [polypeptide binding]; other site
707183002490	active site
707183002491	motif 2; other site
707183002492	motif 3; other site
707183002493	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
707183002494	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
707183002495	active site
707183002496	HIGH motif; other site
707183002497	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
707183002498	KMSKS motif; other site
707183002499	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
707183002500	tRNA binding surface [nucleotide binding]; other site
707183002501	anticodon binding site; other site
707183002502	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
707183002503	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
707183002504	ribonuclease P; Reviewed; Region: rnpA; PRK00730
707183002505	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
707183002506	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
707183002507	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
707183002508	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
707183002509	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
707183002510	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
707183002511	GIY-YIG motif/motif A; other site
707183002512	active site
707183002513	catalytic site [active]
707183002514	putative DNA binding site [nucleotide binding]; other site
707183002515	metal binding site [ion binding]; metal-binding site
707183002516	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
707183002517	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
707183002518	MutS domain I; Region: MutS_I; pfam01624
707183002519	MutS domain II; Region: MutS_II; pfam05188
707183002520	MutS domain III; Region: MutS_III; pfam05192
707183002521	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
707183002522	Walker A/P-loop; other site
707183002523	ATP binding site [chemical binding]; other site
707183002524	Q-loop/lid; other site
707183002525	ABC transporter signature motif; other site
707183002526	Walker B; other site
707183002527	D-loop; other site
707183002528	H-loop/switch region; other site
707183002529	DNA primase; Validated; Region: dnaG; PRK05667
707183002530	CHC2 zinc finger; Region: zf-CHC2; pfam01807
707183002531	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
707183002532	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
707183002533	active site
707183002534	metal binding site [ion binding]; metal-binding site
707183002535	interdomain interaction site; other site
707183002536	glycyl-tRNA synthetase; Provisional; Region: PRK14908
707183002537	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
707183002538	dimer interface [polypeptide binding]; other site
707183002539	motif 1; other site
707183002540	active site
707183002541	motif 2; other site
707183002542	motif 3; other site
707183002543	DALR anticodon binding domain; Region: DALR_1; pfam05746
707183002544	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
707183002545	glycogen synthase; Provisional; Region: glgA; PRK00654
707183002546	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
707183002547	ADP-binding pocket [chemical binding]; other site
707183002548	homodimer interface [polypeptide binding]; other site
707183002549	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
707183002550	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
707183002551	5S rRNA interface [nucleotide binding]; other site
707183002552	CTC domain interface [polypeptide binding]; other site
707183002553	L16 interface [polypeptide binding]; other site
707183002554	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
707183002555	putative active site [active]
707183002556	catalytic residue [active]
707183002557	Ribosomal protein S6 [Translation, ribosomal structure and biogenesis]; Region: RpsF; COG0360
707183002558	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
707183002559	Ribosomal protein L9 [Translation, ribosomal structure and biogenesis]; Region: RplI; COG0359
707183002560	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
707183002561	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
707183002562	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK00650
707183002563	Protein of unknown function (DUF1504); Region: DUF1504; pfam07399
707183002564	Secreted/periplasmic Zn-dependent peptidases, insulinase-like [Posttranslational modification, protein turnover, chaperones]; Region: Ptr; COG1025
707183002565	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
707183002566	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707183002567	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707183002568	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
707183002569	putative acyl-acceptor binding pocket; other site
707183002570	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
707183002571	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
707183002572	homodimer interface [polypeptide binding]; other site
707183002573	oligonucleotide binding site [chemical binding]; other site
707183002574	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
707183002575	putative glycerol-3-phosphate acyltransferase PlsX; Provisional; Region: PRK13846
707183002576	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707183002577	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707183002578	YtxH-like protein; Region: YtxH; cl02079
707183002579	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14314
707183002580	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
707183002581	active site
707183002582	substrate binding site [chemical binding]; other site
707183002583	metal binding site [ion binding]; metal-binding site
707183002584	glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Region: glmS; TIGR01135
707183002585	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
707183002586	glutaminase active site [active]
707183002587	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
707183002588	dimer interface [polypeptide binding]; other site
707183002589	active site
707183002590	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
707183002591	dimer interface [polypeptide binding]; other site
707183002592	active site
707183002593	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; pfam03222
707183002594	aromatic amino acid transport protein; Region: araaP; TIGR00837
707183002595	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; pfam03222
707183002596	aromatic amino acid transport protein; Region: araaP; TIGR00837
707183002597	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
707183002598	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
707183002599	SRP54-type protein, GTPase domain; Region: SRP54; pfam00448
707183002600	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
707183002601	succinyl-CoA synthetase, beta subunit; Region: sucCoAbeta; TIGR01016
707183002602	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
707183002603	CoA-ligase; Region: Ligase_CoA; pfam00549
707183002604	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
707183002605	CoA binding domain; Region: CoA_binding; smart00881
707183002606	CoA-ligase; Region: Ligase_CoA; pfam00549
707183002607	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
707183002608	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
707183002609	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
707183002610	protein binding site [polypeptide binding]; other site
707183002611	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
707183002612	protein binding site [polypeptide binding]; other site
707183002613	Predicted Zn-dependent peptidases, insulinase-like [General function prediction only]; Region: COG1026
707183002614	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
707183002615	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707183002616	Peptidase M16C associated; Region: M16C_assoc; pfam08367
707183002617	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707183002618	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
707183002619	RmuC family; Region: RmuC; pfam02646
707183002620	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
707183002621	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
707183002622	ribonucleotide-diphosphate reductase subunit alpha; Provisional; Region: PRK12365
707183002623	ATP cone domain; Region: ATP-cone; pfam03477
707183002624	ATP cone domain; Region: ATP-cone; pfam03477
707183002625	Class I ribonucleotide reductase; Region: RNR_I; cd01679
707183002626	active site
707183002627	dimer interface [polypeptide binding]; other site
707183002628	catalytic residues [active]
707183002629	effector binding site; other site
707183002630	R2 peptide binding site; other site
707183002631	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
707183002632	dimer interface [polypeptide binding]; other site
707183002633	putative radical transfer pathway; other site
707183002634	diiron center [ion binding]; other site
707183002635	tyrosyl radical; other site
707183002636	Putative methyltransferase; Region: Methyltransf_4; pfam02390
707183002637	Methyltransferase domain; Region: Methyltransf_18; pfam12847
707183002638	Putative rRNA methylase; Region: rRNA_methylase; pfam06962
707183002639	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
707183002640	FAD binding domain; Region: FAD_binding_4; pfam01565
707183002641	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
707183002642	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
707183002643	putative RNA binding site [nucleotide binding]; other site
707183002644	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
707183002645	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
707183002646	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
707183002647	Ribosomal protein L35 [Translation, ribosomal structure and biogenesis]; Region: RpmI; COG0291
707183002648	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
707183002649	23S rRNA binding site [nucleotide binding]; other site
707183002650	L21 binding site [polypeptide binding]; other site
707183002651	L13 binding site [polypeptide binding]; other site
707183002652	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
707183002653	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
707183002654	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
707183002655	motif 1; other site
707183002656	dimer interface [polypeptide binding]; other site
707183002657	active site
707183002658	motif 2; other site
707183002659	motif 3; other site
707183002660	Predicted permeases [General function prediction only]; Region: COG0795
707183002661	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
707183002662	Predicted permeases [General function prediction only]; Region: COG0795
707183002663	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
707183002664	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
707183002665	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
707183002666	Ligand Binding Site [chemical binding]; other site
707183002667	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
707183002668	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707183002669	Walker A motif; other site
707183002670	ATP binding site [chemical binding]; other site
707183002671	Walker B motif; other site
707183002672	arginine finger; other site
707183002673	Peptidase family M41; Region: Peptidase_M41; pfam01434
707183002674	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
707183002675	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
707183002676	RNase E interface [polypeptide binding]; other site
707183002677	trimer interface [polypeptide binding]; other site
707183002678	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
707183002679	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
707183002680	RNase E interface [polypeptide binding]; other site
707183002681	trimer interface [polypeptide binding]; other site
707183002682	active site
707183002683	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
707183002684	putative nucleic acid binding region [nucleotide binding]; other site
707183002685	G-X-X-G motif; other site
707183002686	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
707183002687	RNA binding site [nucleotide binding]; other site
707183002688	domain interface; other site
707183002689	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
707183002690	16S/18S rRNA binding site [nucleotide binding]; other site
707183002691	S13e-L30e interaction site [polypeptide binding]; other site
707183002692	25S rRNA binding site [nucleotide binding]; other site
707183002693	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
707183002694	nucleoside/Zn binding site; other site
707183002695	dimer interface [polypeptide binding]; other site
707183002696	catalytic motif [active]
707183002697	Protein of unknown function (DUF720); Region: DUF720; pfam05302
707183002698	Protein of unknown function (DUF720); Region: DUF720; pfam05302
707183002699	Protein of unknown function (DUF720); Region: DUF720; pfam05302
707183002700	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
707183002701	methionine aminopeptidase; Provisional; Region: PRK12318
707183002702	SEC-C motif; Region: SEC-C; pfam02810
707183002703	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
707183002704	active site
707183002705	MarC family integral membrane protein; Region: MarC; pfam01914
707183002706	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
707183002707	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
707183002708	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707183002709	dimer interface [polypeptide binding]; other site
707183002710	conserved gate region; other site
707183002711	putative PBP binding loops; other site
707183002712	ABC-ATPase subunit interface; other site
707183002713	NMT1/THI5 like; Region: NMT1; pfam09084
707183002714	fumarate hydratase, class II; Region: fumC_II; TIGR00979
707183002715	Class II fumarases; Region: Fumarase_classII; cd01362
707183002716	active site
707183002717	tetramer interface [polypeptide binding]; other site
707183002718	high affinity sulphate transporter 1; Region: sulP; TIGR00815
707183002719	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
707183002720	Sulfate transporter family; Region: Sulfate_transp; pfam00916
707183002721	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
707183002722	Na+/H+ antiporter, NhaD family; Region: NhaD; TIGR00775
707183002723	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
707183002724	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
707183002725	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
707183002726	Interphotoreceptor retinoid-binding protein; serine protease family S41; Region: Peptidase_S41_IRBP; cd07563
707183002727	active site triad [active]
707183002728	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
707183002729	LytB protein; Region: LYTB; pfam02401
707183002730	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
707183002731	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
707183002732	binding surface
707183002733	TPR motif; other site
707183002734	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
707183002735	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
707183002736	active site
707183002737	DNA binding site [nucleotide binding]
707183002738	Int/Topo IB signature motif; other site
707183002739	glycogen branching enzyme; Provisional; Region: PRK05402
707183002740	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
707183002741	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
707183002742	active site
707183002743	catalytic site [active]
707183002744	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
707183002745	Ulp1 protease family, C-terminal catalytic domain; Region: Peptidase_C48; cl17784
707183002746	Ulp1 protease family, C-terminal catalytic domain; Region: Peptidase_C48; cl17784
707183002747	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707183002748	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707183002749	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707183002750	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707183002751	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707183002752	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707183002753	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707183002754	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707183002755	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707183002756	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707183002757	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707183002758	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707183002759	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707183002760	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707183002761	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707183002762	Autotransporter beta-domain; Region: Autotransporter; pfam03797