-- dump date   	20140619_024942
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1105111000001	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
1105111000002	AAA domain; Region: AAA_30; pfam13604
1105111000003	Family description; Region: UvrD_C_2; pfam13538
1105111000004	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1105111000005	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1105111000006	catalytic residues [active]
1105111000007	catalytic nucleophile [active]
1105111000008	Presynaptic Site I dimer interface [polypeptide binding]; other site
1105111000009	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1105111000010	Synaptic Flat tetramer interface [polypeptide binding]; other site
1105111000011	Synaptic Site I dimer interface [polypeptide binding]; other site
1105111000012	DNA binding site [nucleotide binding]
1105111000013	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1105111000014	DNA-binding interface [nucleotide binding]; DNA binding site
1105111000015	Patatin-like phospholipase; includes PNPLA8, PNPLA9, and Pat17; Region: Pat17_PNPLA8_PNPLA9_like; cd07199
1105111000016	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1105111000017	active site
1105111000018	nucleophile elbow; other site
1105111000019	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1105111000020	TMP-binding site; other site
1105111000021	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105111000022	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105111000023	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1105111000024	binding surface
1105111000025	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111000026	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1105111000027	TPR motif; other site
1105111000028	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105111000029	non-specific DNA binding site [nucleotide binding]; other site
1105111000030	salt bridge; other site
1105111000031	sequence-specific DNA binding site [nucleotide binding]; other site
1105111000032	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1105111000033	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105111000034	P-loop; other site
1105111000035	Magnesium ion binding site [ion binding]; other site
1105111000036	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111000037	Walker A motif; other site
1105111000038	ATP binding site [chemical binding]; other site
1105111000039	Walker B motif; other site
1105111000040	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1105111000041	Helix-turn-helix domain; Region: HTH_38; pfam13936
1105111000042	Integrase core domain; Region: rve; pfam00665
1105111000043	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1105111000044	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105111000045	non-specific DNA binding site [nucleotide binding]; other site
1105111000046	salt bridge; other site
1105111000047	sequence-specific DNA binding site [nucleotide binding]; other site
1105111000048	Sex factor F TraW protein N terminal; Region: TraW_N; cl10149
1105111000049	potential frameshift: common BLAST hit: gi|113473810|ref|YP_718073.1| sex pilus assembly and synthesis protein
1105111000050	TraU protein; Region: TraU; cl06067
1105111000051	putative transposase; Provisional; Region: PRK09857
1105111000052	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105111000053	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1105111000054	active site
1105111000055	metal binding site [ion binding]; metal-binding site
1105111000056	interdomain interaction site; other site
1105111000057	potential frameshift: common BLAST hit: gi|67459877|ref|YP_247499.1| conjugative transfer protein TraA_Ti
1105111000058	potential frameshift: common BLAST hit: gi|67459877|ref|YP_247499.1| conjugative transfer protein TraA_Ti
1105111000059	Conjugal transfer protein TraD; Region: TraD; pfam06412
1105111000060	Uncharacterized conserved protein [Function unknown]; Region: COG4095
1105111000061	WGR domain; Region: WGR; cl01581
1105111000062	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1105111000063	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
1105111000064	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1105111000065	putative transposase; Provisional; Region: PRK09857
1105111000066	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105111000067	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1105111000068	active site
1105111000069	metal binding site [ion binding]; metal-binding site
1105111000070	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1105111000071	active site
1105111000072	substrate binding site [chemical binding]; other site
1105111000073	catalytic site [active]
1105111000074	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1105111000075	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
1105111000076	putative dimer interface [polypeptide binding]; other site
1105111000077	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1105111000078	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
1105111000079	putative dimer interface [polypeptide binding]; other site
1105111000080	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1105111000081	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1105111000082	catalytic residues [active]
1105111000083	catalytic nucleophile [active]
1105111000084	Presynaptic Site I dimer interface [polypeptide binding]; other site
1105111000085	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1105111000086	Synaptic Flat tetramer interface [polypeptide binding]; other site
1105111000087	Synaptic Site I dimer interface [polypeptide binding]; other site
1105111000088	DNA binding site [nucleotide binding]
1105111000089	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
1105111000090	DNA photolyase; Region: DNA_photolyase; pfam00875
1105111000091	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1105111000092	MULE transposase domain; Region: MULE; pfam10551
1105111000093	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1105111000094	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1105111000095	potential frameshift: common BLAST hit: gi|67459899|ref|YP_247521.1| transposase
1105111000096	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
1105111000097	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1105111000098	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1105111000099	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105111000100	P-loop; other site
1105111000101	Magnesium ion binding site [ion binding]; other site
1105111000102	Ferredoxin [Energy production and conversion]; Region: COG1146
1105111000103	4Fe-4S binding domain; Region: Fer4; cl02805
1105111000104	heme exporter protein CcmC; Region: ccmC; TIGR01191
1105111000105	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1105111000106	Cation efflux family; Region: Cation_efflux; cl00316
1105111000107	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1105111000108	nucleoside/Zn binding site; other site
1105111000109	dimer interface [polypeptide binding]; other site
1105111000110	catalytic motif [active]
1105111000111	Surface antigen [Cell envelope biogenesis, outer membrane]; Region: LipA; COG4520
1105111000112	PhosphatidylEthanolamine-Binding Protein (PEBP) domain; Region: PEBP; cl00227
1105111000113	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1105111000114	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1105111000115	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1105111000116	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1105111000117	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1105111000118	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1105111000119	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1105111000120	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1105111000121	dimer interface [polypeptide binding]; other site
1105111000122	ssDNA binding site [nucleotide binding]; other site
1105111000123	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1105111000124	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
1105111000125	hypothetical protein; Reviewed; Region: PRK01530
1105111000126	heat shock protein 90; Provisional; Region: PRK05218
1105111000127	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105111000128	ATP binding site [chemical binding]; other site
1105111000129	Mg2+ binding site [ion binding]; other site
1105111000130	G-X-G motif; other site
1105111000131	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1105111000132	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1105111000133	substrate-cofactor binding pocket; other site
1105111000134	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105111000135	catalytic residue [active]
1105111000136	trigger factor; Provisional; Region: tig; PRK01490
1105111000137	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1105111000138	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1105111000139	GTPase CgtA; Reviewed; Region: obgE; PRK12299
1105111000140	GTP1/OBG; Region: GTP1_OBG; pfam01018
1105111000141	Obg GTPase; Region: Obg; cd01898
1105111000142	G1 box; other site
1105111000143	GTP/Mg2+ binding site [chemical binding]; other site
1105111000144	Switch I region; other site
1105111000145	G2 box; other site
1105111000146	G3 box; other site
1105111000147	Switch II region; other site
1105111000148	G4 box; other site
1105111000149	G5 box; other site
1105111000150	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1105111000151	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1105111000152	dimer interface [polypeptide binding]; other site
1105111000153	active site
1105111000154	citrylCoA binding site [chemical binding]; other site
1105111000155	NADH binding [chemical binding]; other site
1105111000156	cationic pore residues; other site
1105111000157	oxalacetate/citrate binding site [chemical binding]; other site
1105111000158	coenzyme A binding site [chemical binding]; other site
1105111000159	catalytic triad [active]
1105111000160	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
1105111000161	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
1105111000162	Fe-S cluster binding site [ion binding]; other site
1105111000163	active site
1105111000164	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1105111000165	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105111000166	RNA binding surface [nucleotide binding]; other site
1105111000167	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1105111000168	active site
1105111000169	potential frameshift: common BLAST hit: gi|157964997|ref|YP_001499821.1| bifunctional N5-glutamine S-adenosyl-L-methionine-dependent
1105111000170	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1105111000171	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1105111000172	Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; Region: GlyS; COG0751
1105111000173	DALR anticodon binding domain; Region: DALR_1; pfam05746
1105111000174	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
1105111000175	motif 1; other site
1105111000176	dimer interface [polypeptide binding]; other site
1105111000177	active site
1105111000178	motif 2; other site
1105111000179	motif 3; other site
1105111000180	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1105111000181	oligomeric interface; other site
1105111000182	putative active site [active]
1105111000183	homodimer interface [polypeptide binding]; other site
1105111000184	prevent-host-death family protein; Region: phd_fam; TIGR01552
1105111000185	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
1105111000186	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111000187	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105111000188	putative substrate translocation pore; other site
1105111000189	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1105111000190	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1105111000191	motif 1; other site
1105111000192	active site
1105111000193	motif 2; other site
1105111000194	motif 3; other site
1105111000195	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1105111000196	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1105111000197	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1105111000198	dimerization interface 3.5A [polypeptide binding]; other site
1105111000199	active site
1105111000200	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
1105111000201	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1105111000202	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1105111000203	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1105111000204	DNA binding residues [nucleotide binding]
1105111000205	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1105111000206	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1105111000207	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1105111000208	DNA primase, catalytic core; Region: dnaG; TIGR01391
1105111000209	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1105111000210	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1105111000211	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1105111000212	active site
1105111000213	metal binding site [ion binding]; metal-binding site
1105111000214	interdomain interaction site; other site
1105111000215	Dolichol kinase [Lipid metabolism]; Region: SEC59; COG0170
1105111000216	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1105111000217	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1105111000218	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1105111000219	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
1105111000220	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1105111000221	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1105111000222	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
1105111000223	ligand binding site [chemical binding]; other site
1105111000224	homodimer interface [polypeptide binding]; other site
1105111000225	NAD(P) binding site [chemical binding]; other site
1105111000226	trimer interface B [polypeptide binding]; other site
1105111000227	trimer interface A [polypeptide binding]; other site
1105111000228	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1105111000229	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
1105111000230	DNA polymerase III subunits gamma and tau; Validated; Region: PRK06645
1105111000231	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111000232	Walker A motif; other site
1105111000233	ATP binding site [chemical binding]; other site
1105111000234	Walker B motif; other site
1105111000235	arginine finger; other site
1105111000236	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1105111000237	hypothetical protein; Validated; Region: PRK00153
1105111000238	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cl02529
1105111000239	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111000240	Predicted aspartyl protease [General function prediction only]; Region: COG3577
1105111000241	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
1105111000242	catalytic motif [active]
1105111000243	Catalytic residue [active]
1105111000244	Beta-lactamase; Region: Beta-lactamase; pfam00144
1105111000245	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1105111000246	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1105111000247	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1105111000248	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105111000249	Walker A/P-loop; other site
1105111000250	ATP binding site [chemical binding]; other site
1105111000251	Q-loop/lid; other site
1105111000252	ABC transporter signature motif; other site
1105111000253	Walker B; other site
1105111000254	D-loop; other site
1105111000255	H-loop/switch region; other site
1105111000256	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1105111000257	putative hydrolase; Provisional; Region: PRK02113
1105111000258	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1105111000259	active site
1105111000260	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
1105111000261	Predicted permeases [General function prediction only]; Region: COG0795
1105111000262	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1105111000263	DNA polymerase III subunit chi; Provisional; Region: PRK06646
1105111000264	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1105111000265	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1105111000266	metal binding site [ion binding]; metal-binding site
1105111000267	dimer interface [polypeptide binding]; other site
1105111000268	potential frameshift: common BLAST hit: gi|229587245|ref|YP_002845746.1| Type I restriction/modification enzyme endonuclease S subunit
1105111000269	potential frameshift: common BLAST hit: gi|157827849|ref|YP_001496913.1| Type I restriction-modification system methyltransferase subunit
1105111000270	potential frameshift: common BLAST hit: gi|157827849|ref|YP_001496913.1| Type I restriction-modification system methyltransferase subunit
1105111000271	potential frameshift: common BLAST hit: gi|157965011|ref|YP_001499835.1| Na+/H+ antiporter NhaA
1105111000272	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1105111000273	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1105111000274	putative active site [active]
1105111000275	lipoate-protein ligase B; Provisional; Region: PRK14347
1105111000276	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1105111000277	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1105111000278	amidase catalytic site [active]
1105111000279	Zn binding residues [ion binding]; other site
1105111000280	substrate binding site [chemical binding]; other site
1105111000281	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1105111000282	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1105111000283	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1105111000284	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1105111000285	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105111000286	ATP binding site [chemical binding]; other site
1105111000287	Mg2+ binding site [ion binding]; other site
1105111000288	G-X-G motif; other site
1105111000289	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1105111000290	ATP binding site [chemical binding]; other site
1105111000291	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1105111000292	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4391
1105111000293	potential frameshift: common BLAST hit: gi|157827810|ref|YP_001496874.1| oxidoreductase
1105111000294	TPR repeat; Region: TPR_11; pfam13414
1105111000295	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111000296	binding surface
1105111000297	TPR motif; other site
1105111000298	TPR repeat; Region: TPR_11; pfam13414
1105111000299	potential frameshift: common BLAST hit: gi|374319874|ref|YP_005066374.1| Tetratricopeptide repeat-containing protein
1105111000300	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111000301	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105111000302	putative substrate translocation pore; other site
1105111000303	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1105111000304	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1105111000305	potential frameshift: common BLAST hit: gi|67459789|ref|YP_247413.1| prophage antirepressor
1105111000306	BRO family, N-terminal domain; Region: Bro-N; cl10591
1105111000307	TIGR00701 family protein; Region: TIGR00701
1105111000308	ferrochelatase; Reviewed; Region: hemH; PRK00035
1105111000309	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1105111000310	C-terminal domain interface [polypeptide binding]; other site
1105111000311	active site
1105111000312	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1105111000313	active site
1105111000314	N-terminal domain interface [polypeptide binding]; other site
1105111000315	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1105111000316	substrate binding site [chemical binding]; other site
1105111000317	active site
1105111000318	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1806
1105111000319	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1105111000320	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1105111000321	catalytic residues [active]
1105111000322	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1105111000323	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1105111000324	Walker A/P-loop; other site
1105111000325	ATP binding site [chemical binding]; other site
1105111000326	Q-loop/lid; other site
1105111000327	ABC transporter signature motif; other site
1105111000328	Walker B; other site
1105111000329	D-loop; other site
1105111000330	H-loop/switch region; other site
1105111000331	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1105111000332	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1105111000333	putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; Validated; Region: PRK06567
1105111000334	FAD/NAD binding domain (electron transfer subunit) of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate...; Region: DHOD_e_trans_like; cd06192
1105111000335	FAD binding pocket [chemical binding]; other site
1105111000336	FAD binding motif [chemical binding]; other site
1105111000337	phosphate binding motif [ion binding]; other site
1105111000338	beta-alpha-beta structure motif; other site
1105111000339	NAD binding pocket [chemical binding]; other site
1105111000340	Iron coordination center [ion binding]; other site
1105111000341	Growth inhibitor [Signal transduction mechanisms]; Region: MazF; COG2337
1105111000342	Acyl-[acyl carrier protein]; Region: LpxA; COG1043
1105111000343	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1105111000344	active site
1105111000345	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1105111000346	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1105111000347	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1105111000348	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1105111000349	trimer interface [polypeptide binding]; other site
1105111000350	active site
1105111000351	UDP-GlcNAc binding site [chemical binding]; other site
1105111000352	lipid binding site [chemical binding]; lipid-binding site
1105111000353	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
1105111000354	active site
1105111000355	vitamin B12-dependent ribonucleotide reductase; Validated; Region: PRK06556
1105111000356	potential frameshift: common BLAST hit: gi|67458401|ref|YP_246025.1| alpha-beta hydrolase family esterase
1105111000357	potential frameshift: common BLAST hit: gi|157827876|ref|YP_001494118.1| ankyrin repeat-containing protein
1105111000358	potential frameshift: common BLAST hit: gi|67458403|ref|YP_246027.1| ankyrin repeat-containing protein
1105111000359	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111000360	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111000361	Protein of unknown function (DUF2748); Region: DUF2748; pfam10871
1105111000362	potential frameshift: common BLAST hit: gi|67458439|ref|YP_246063.1| cell surface antigen-like protein Sca10
1105111000363	potential frameshift: common BLAST hit: gi|341583274|ref|YP_004763765.1| cell surface antigen-like protein Sca10
1105111000364	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1105111000365	Colicin V production protein; Region: Colicin_V; pfam02674
1105111000366	Putative transcriptional regulator [Transcription]; Region: COG1678
1105111000367	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1105111000368	potential frameshift: common BLAST hit: gi|67458431|ref|YP_246055.1| folate synthesis bifunctional protein
1105111000369	potential frameshift: common BLAST hit: gi|67458431|ref|YP_246055.1| folate synthesis bifunctional protein
1105111000370	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1105111000371	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1105111000372	NADP+ binding site [chemical binding]; other site
1105111000373	folate binding site [chemical binding]; other site
1105111000374	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
1105111000375	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
1105111000376	Recombinational DNA repair ATPase (RecF pathway) [DNA replication, recombination, and repair]; Region: RecF; COG1195
1105111000377	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105111000378	Walker A/P-loop; other site
1105111000379	ATP binding site [chemical binding]; other site
1105111000380	Q-loop/lid; other site
1105111000381	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105111000382	ABC transporter signature motif; other site
1105111000383	Walker B; other site
1105111000384	D-loop; other site
1105111000385	H-loop/switch region; other site
1105111000386	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1105111000387	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105111000388	S-adenosylmethionine binding site [chemical binding]; other site
1105111000389	Predicted regulatory domain of a methyltransferase [General function prediction only]; Region: COG4797
1105111000390	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1105111000391	Transcriptional regulators, similar to M. xanthus CarD [Transcription]; Region: COG1329
1105111000392	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1105111000393	DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972
1105111000394	catalytic residues [active]
1105111000395	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5336
1105111000396	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1105111000397	ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Region: ATP_synt_6_or_A; TIGR01131
1105111000398	F0F1 ATP synthase subunit C; Validated; Region: PRK07558
1105111000399	F0F1 ATP synthase subunit B'; Validated; Region: PRK06569
1105111000400	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1105111000401	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1105111000402	F0F1 ATP synthase subunit B; Validated; Region: PRK06568
1105111000403	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1105111000404	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
1105111000405	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1105111000406	active site
1105111000407	NTP binding site [chemical binding]; other site
1105111000408	metal binding triad [ion binding]; metal-binding site
1105111000409	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1105111000410	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1105111000411	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1105111000412	intersubunit interface [polypeptide binding]; other site
1105111000413	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1105111000414	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1105111000415	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1105111000416	FMN binding site [chemical binding]; other site
1105111000417	active site
1105111000418	catalytic residues [active]
1105111000419	substrate binding site [chemical binding]; other site
1105111000420	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111000421	potential frameshift: common BLAST hit: gi|15891977|ref|NP_359691.1| acetoacetyl-CoA reductase
1105111000422	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1105111000423	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111000424	Walker A motif; other site
1105111000425	ATP binding site [chemical binding]; other site
1105111000426	Walker B motif; other site
1105111000427	arginine finger; other site
1105111000428	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111000429	Walker A motif; other site
1105111000430	ATP binding site [chemical binding]; other site
1105111000431	Walker B motif; other site
1105111000432	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1105111000433	UGMP family protein; Validated; Region: PRK09604
1105111000434	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1105111000435	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
1105111000436	Fatty acid desaturase; Region: FA_desaturase; pfam00487
1105111000437	Di-iron ligands [ion binding]; other site
1105111000438	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
1105111000439	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1105111000440	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1105111000441	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1105111000442	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1105111000443	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1105111000444	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1105111000445	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1105111000446	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1105111000447	Ligand Binding Site [chemical binding]; other site
1105111000448	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111000449	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111000450	FtsH Extracellular; Region: FtsH_ext; pfam06480
1105111000451	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1105111000452	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111000453	Walker A motif; other site
1105111000454	ATP binding site [chemical binding]; other site
1105111000455	Walker B motif; other site
1105111000456	arginine finger; other site
1105111000457	Peptidase family M41; Region: Peptidase_M41; pfam01434
1105111000458	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1105111000459	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1105111000460	Uncharacterized conserved protein [Function unknown]; Region: COG1565
1105111000461	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111000462	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1105111000463	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1105111000464	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1105111000465	membrane protein insertase; Provisional; Region: PRK01318
1105111000466	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1105111000467	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1105111000468	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1105111000469	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105111000470	S-adenosylmethionine binding site [chemical binding]; other site
1105111000471	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105111000472	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1105111000473	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111000474	putative substrate translocation pore; other site
1105111000475	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1105111000476	active site
1105111000477	multimer interface [polypeptide binding]; other site
1105111000478	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1105111000479	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1105111000480	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1105111000481	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1105111000482	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; cl17726
1105111000483	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1105111000484	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105111000485	P-loop; other site
1105111000486	Magnesium ion binding site [ion binding]; other site
1105111000487	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105111000488	Magnesium ion binding site [ion binding]; other site
1105111000489	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1105111000490	ParB-like nuclease domain; Region: ParB; smart00470
1105111000491	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1105111000492	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105111000493	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105111000494	ABC transporter; Region: ABC_tran_2; pfam12848
1105111000495	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105111000496	Protein of unknown function (DUF2672); Region: DUF2672; pfam10878
1105111000497	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
1105111000498	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1105111000499	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1105111000500	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
1105111000501	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1105111000502	Zn2+ binding site [ion binding]; other site
1105111000503	Mg2+ binding site [ion binding]; other site
1105111000504	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1105111000505	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1105111000506	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
1105111000507	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1105111000508	active site
1105111000509	HIGH motif; other site
1105111000510	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105111000511	KMSK motif region; other site
1105111000512	tRNA binding surface [nucleotide binding]; other site
1105111000513	DALR anticodon binding domain; Region: DALR_1; smart00836
1105111000514	anticodon binding site; other site
1105111000515	Sporulation related domain; Region: SPOR; pfam05036
1105111000516	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1105111000517	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1105111000518	CAP-like domain; other site
1105111000519	active site
1105111000520	primary dimer interface [polypeptide binding]; other site
1105111000521	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105111000522	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105111000523	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105111000524	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105111000525	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105111000526	type IV secretion system ATPase VirB4; Provisional; Region: PRK13898
1105111000527	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1105111000528	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105111000529	Walker A/P-loop; other site
1105111000530	ATP binding site [chemical binding]; other site
1105111000531	type IV secretion system protein VirB3; Provisional; Region: PRK13899
1105111000532	Acetylglutamate kinase [Amino acid transport and metabolism]; Region: ArgB; COG0548
1105111000533	substrate binding site [chemical binding]; other site
1105111000534	nucleotide binding site [chemical binding]; other site
1105111000535	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1105111000536	G1 box; other site
1105111000537	GTP/Mg2+ binding site [chemical binding]; other site
1105111000538	Switch I region; other site
1105111000539	G2 box; other site
1105111000540	G3 box; other site
1105111000541	Switch II region; other site
1105111000542	G4 box; other site
1105111000543	G5 box; other site
1105111000544	50S ribosomal protein L31; Provisional; Region: PRK01397
1105111000545	Ribosomal protein L28 [Translation, ribosomal structure and biogenesis]; Region: RpmB; COG0227
1105111000546	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1105111000547	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105111000548	Walker A/P-loop; other site
1105111000549	ATP binding site [chemical binding]; other site
1105111000550	Q-loop/lid; other site
1105111000551	ABC transporter signature motif; other site
1105111000552	Walker B; other site
1105111000553	D-loop; other site
1105111000554	H-loop/switch region; other site
1105111000555	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1105111000556	Permease; Region: Permease; pfam02405
1105111000557	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
1105111000558	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1105111000559	active site
1105111000560	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1105111000561	dimer interface [polypeptide binding]; other site
1105111000562	substrate binding site [chemical binding]; other site
1105111000563	catalytic residues [active]
1105111000564	Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism]; Region: PrsA; COG0462
1105111000565	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1105111000566	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1105111000567	active site
1105111000568	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111000569	ABC-type transport system involved in resistance to organic solvents, auxiliary component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2D; COG2854
1105111000570	Surface lipoprotein [Cell envelope biogenesis, outer membrane]; Region: VacJ; COG2853
1105111000571	TPR repeat; Region: TPR_11; pfam13414
1105111000572	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111000573	binding surface
1105111000574	TPR motif; other site
1105111000575	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1105111000576	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105111000577	S-adenosylmethionine binding site [chemical binding]; other site
1105111000578	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
1105111000579	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
1105111000580	aspartate aminotransferase; Provisional; Region: PRK05764
1105111000581	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1105111000582	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105111000583	homodimer interface [polypeptide binding]; other site
1105111000584	catalytic residue [active]
1105111000585	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
1105111000586	putative acyl-acceptor binding pocket; other site
1105111000587	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1105111000588	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111000589	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1105111000590	elongation factor Ts; Provisional; Region: tsf; PRK09377
1105111000591	UBA/TS-N domain; Region: UBA; pfam00627
1105111000592	Elongation factor TS; Region: EF_TS; pfam00889
1105111000593	Elongation factor TS; Region: EF_TS; pfam00889
1105111000594	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1105111000595	rRNA interaction site [nucleotide binding]; other site
1105111000596	S8 interaction site; other site
1105111000597	putative laminin-1 binding site; other site
1105111000598	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1105111000599	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1105111000600	active site
1105111000601	HIGH motif; other site
1105111000602	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1105111000603	KMSKS motif; other site
1105111000604	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1105111000605	tRNA binding surface [nucleotide binding]; other site
1105111000606	anticodon binding site; other site
1105111000607	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1105111000608	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
1105111000609	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111000610	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105111000611	putative substrate translocation pore; other site
1105111000612	EamA-like transporter family; Region: EamA; pfam00892
1105111000613	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1105111000614	EamA-like transporter family; Region: EamA; pfam00892
1105111000615	Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047
1105111000616	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
1105111000617	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1105111000618	Protein of unknown function (DUF1013); Region: DUF1013; cl11533
1105111000619	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1105111000620	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1105111000621	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1105111000622	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1105111000623	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105111000624	active site
1105111000625	phosphorylation site [posttranslational modification]
1105111000626	intermolecular recognition site; other site
1105111000627	dimerization interface [polypeptide binding]; other site
1105111000628	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1105111000629	DNA binding site [nucleotide binding]
1105111000630	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1105111000631	SecA binding site; other site
1105111000632	Preprotein binding site; other site
1105111000633	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1105111000634	trimer interface [polypeptide binding]; other site
1105111000635	active site
1105111000636	Gram-negative porin; Region: Porin_4; pfam13609
1105111000637	tRNA-(guanine-N1)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmD; COG0336
1105111000638	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1105111000639	hypothetical protein; Provisional; Region: PRK13694
1105111000640	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1105111000641	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1105111000642	Protein export membrane protein; Region: SecD_SecF; pfam02355
1105111000643	NADH dehydrogenase I subunit F; Provisional; Region: PRK13596
1105111000644	SLBB domain; Region: SLBB; pfam10531
1105111000645	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
1105111000646	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1105111000647	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1105111000648	Catalytic site [active]
1105111000649	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1105111000650	ribonuclease III; Reviewed; Region: rnc; PRK00102
1105111000651	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1105111000652	dimerization interface [polypeptide binding]; other site
1105111000653	active site
1105111000654	metal binding site [ion binding]; metal-binding site
1105111000655	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1105111000656	dsRNA binding site [nucleotide binding]; other site
1105111000657	GTPase Era; Provisional; Region: era; PRK15494
1105111000658	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111000659	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1105111000660	G1 box; other site
1105111000661	GTP/Mg2+ binding site [chemical binding]; other site
1105111000662	Switch I region; other site
1105111000663	G2 box; other site
1105111000664	Switch II region; other site
1105111000665	G3 box; other site
1105111000666	G4 box; other site
1105111000667	G5 box; other site
1105111000668	KH domain; Region: KH_2; pfam07650
1105111000669	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1105111000670	active site
1105111000671	putative DNA-binding cleft [nucleotide binding]; other site
1105111000672	dimer interface [polypeptide binding]; other site
1105111000673	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1105111000674	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1105111000675	nucleotidyltransferase substrate binding protein, HI0074 family; Region: HI0074; TIGR01987
1105111000676	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1105111000677	active site
1105111000678	NTP binding site [chemical binding]; other site
1105111000679	metal binding triad [ion binding]; metal-binding site
1105111000680	antibiotic binding site [chemical binding]; other site
1105111000681	Predicted nucleoside-diphosphate-sugar epimerase [Cell envelope biogenesis, outer membrane]; Region: COG3660
1105111000682	Mitochondrial fission ELM1; Region: Mito_fiss_Elm1; pfam06258
1105111000683	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1105111000684	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1105111000685	Walker A motif; other site
1105111000686	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1105111000687	HflK protein; Region: hflK; TIGR01933
1105111000688	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1105111000689	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1105111000690	potential frameshift: common BLAST hit: gi|229586364|ref|YP_002844865.1| Periplasmic serine protease
1105111000691	hypothetical protein; Validated; Region: PRK01415
1105111000692	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1105111000693	active site residue [active]
1105111000694	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1105111000695	Iron-sulfur protein interface; other site
1105111000696	proximal quinone binding site [chemical binding]; other site
1105111000697	SdhD (CybS) interface [polypeptide binding]; other site
1105111000698	proximal heme binding site [chemical binding]; other site
1105111000699	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit-like; composed of predominantly uncharacterized bacterial proteins with similarity to the E. coli SdhD subunit. One characterized protein is the respiratory...; Region: SQR_TypeC_SdhD_like; cd03495
1105111000700	putative SdhC subunit interface [polypeptide binding]; other site
1105111000701	putative proximal heme binding site [chemical binding]; other site
1105111000702	putative Iron-sulfur protein interface [polypeptide binding]; other site
1105111000703	putative proximal quinone binding site; other site
1105111000704	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK09078
1105111000705	L-aspartate oxidase; Provisional; Region: PRK06175
1105111000706	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1105111000707	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1105111000708	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1105111000709	dimer interface [polypeptide binding]; other site
1105111000710	conserved gate region; other site
1105111000711	putative PBP binding loops; other site
1105111000712	ABC-ATPase subunit interface; other site
1105111000713	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1105111000714	S17 interaction site [polypeptide binding]; other site
1105111000715	S8 interaction site; other site
1105111000716	16S rRNA interaction site [nucleotide binding]; other site
1105111000717	streptomycin interaction site [chemical binding]; other site
1105111000718	23S rRNA interaction site [nucleotide binding]; other site
1105111000719	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1105111000720	30S ribosomal protein S7; Validated; Region: PRK05302
1105111000721	elongation factor G; Reviewed; Region: PRK00007
1105111000722	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1105111000723	G1 box; other site
1105111000724	putative GEF interaction site [polypeptide binding]; other site
1105111000725	GTP/Mg2+ binding site [chemical binding]; other site
1105111000726	Switch I region; other site
1105111000727	G2 box; other site
1105111000728	G3 box; other site
1105111000729	Switch II region; other site
1105111000730	G4 box; other site
1105111000731	G5 box; other site
1105111000732	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1105111000733	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1105111000734	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1105111000735	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
1105111000736	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1105111000737	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1105111000738	putative homodimer interface [polypeptide binding]; other site
1105111000739	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1105111000740	heterodimer interface [polypeptide binding]; other site
1105111000741	homodimer interface [polypeptide binding]; other site
1105111000742	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1105111000743	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1105111000744	23S rRNA interface [nucleotide binding]; other site
1105111000745	putative thiostrepton binding site; other site
1105111000746	L7/L12 interface [polypeptide binding]; other site
1105111000747	L25 interface [polypeptide binding]; other site
1105111000748	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1105111000749	mRNA/rRNA interface [nucleotide binding]; other site
1105111000750	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1105111000751	23S rRNA interface [nucleotide binding]; other site
1105111000752	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1105111000753	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1105111000754	core dimer interface [polypeptide binding]; other site
1105111000755	peripheral dimer interface [polypeptide binding]; other site
1105111000756	L10 interface [polypeptide binding]; other site
1105111000757	L11 interface [polypeptide binding]; other site
1105111000758	putative EF-Tu interaction site [polypeptide binding]; other site
1105111000759	putative EF-G interaction site [polypeptide binding]; other site
1105111000760	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1105111000761	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1105111000762	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1105111000763	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1105111000764	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1105111000765	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1105111000766	RPB3 interaction site [polypeptide binding]; other site
1105111000767	RPB1 interaction site [polypeptide binding]; other site
1105111000768	RPB11 interaction site [polypeptide binding]; other site
1105111000769	RPB10 interaction site [polypeptide binding]; other site
1105111000770	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1105111000771	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1105111000772	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1105111000773	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1105111000774	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1105111000775	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1105111000776	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1105111000777	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1105111000778	DNA binding site [nucleotide binding]
1105111000779	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1105111000780	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111000781	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1105111000782	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1105111000783	interface (dimer of trimers) [polypeptide binding]; other site
1105111000784	Substrate-binding/catalytic site; other site
1105111000785	Zn-binding sites [ion binding]; other site
1105111000786	ATPase MipZ; Region: MipZ; pfam09140
1105111000787	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105111000788	P-loop; other site
1105111000789	Magnesium ion binding site [ion binding]; other site
1105111000790	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1105111000791	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1105111000792	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1105111000793	dimer interface [polypeptide binding]; other site
1105111000794	anticodon binding site; other site
1105111000795	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1105111000796	homodimer interface [polypeptide binding]; other site
1105111000797	motif 1; other site
1105111000798	active site
1105111000799	motif 2; other site
1105111000800	GAD domain; Region: GAD; pfam02938
1105111000801	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1105111000802	active site
1105111000803	motif 3; other site
1105111000804	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1105111000805	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1105111000806	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1105111000807	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1105111000808	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1105111000809	Flavin reductase like domain; Region: Flavin_Reduct; smart00903
1105111000810	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1105111000811	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1105111000812	substrate binding pocket [chemical binding]; other site
1105111000813	membrane-bound complex binding site; other site
1105111000814	hinge residues; other site
1105111000815	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1105111000816	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1105111000817	GatB domain; Region: GatB_Yqey; smart00845
1105111000818	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1105111000819	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1105111000820	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1105111000821	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1105111000822	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1105111000823	hinge region; other site
1105111000824	potential frameshift: common BLAST hit: gi|157964222|ref|YP_001499046.1| uridylate kinase
1105111000825	putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK06580
1105111000826	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1105111000827	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111000828	putative substrate translocation pore; other site
1105111000829	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111000830	Protein of unknown function (DUF2674); Region: DUF2674; pfam10879
1105111000831	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1105111000832	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105111000833	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105111000834	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105111000835	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105111000836	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105111000837	Surface antigen; Region: Bac_surface_Ag; pfam01103
1105111000838	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
1105111000839	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1105111000840	active site
1105111000841	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1105111000842	protein binding site [polypeptide binding]; other site
1105111000843	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1105111000844	putative substrate binding region [chemical binding]; other site
1105111000845	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
1105111000846	putative RNA binding site [nucleotide binding]; other site
1105111000847	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1105111000848	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105111000849	S-adenosylmethionine binding site [chemical binding]; other site
1105111000850	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1105111000851	putative coenzyme Q binding site [chemical binding]; other site
1105111000852	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111000853	Uncharacterized conserved small protein [Function unknown]; Region: COG5508
1105111000854	Protein of unknown function (DUF1674); Region: DUF1674; pfam07896
1105111000855	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1105111000856	RNA methyltransferase, RsmE family; Region: TIGR00046
1105111000857	Uncharacterized conserved protein [Function unknown]; Region: COG2155
1105111000858	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1105111000859	Protein export membrane protein; Region: SecD_SecF; cl14618
1105111000860	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1105111000861	IHF dimer interface [polypeptide binding]; other site
1105111000862	IHF - DNA interface [nucleotide binding]; other site
1105111000863	DNA polymerase III subunit delta'; Validated; Region: PRK06581
1105111000864	signal recognition particle protein; Provisional; Region: PRK10867
1105111000865	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1105111000866	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1105111000867	P loop; other site
1105111000868	GTP binding site [chemical binding]; other site
1105111000869	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1105111000870	potential frameshift: common BLAST hit: gi|51473374|ref|YP_067131.1| post-proline cleaving enzyme
1105111000871	potential frameshift: common BLAST hit: gi|51473374|ref|YP_067131.1| post-proline cleaving enzyme
1105111000872	potential frameshift: common BLAST hit: gi|67459496|ref|YP_247120.1| prolyl endopeptidase
1105111000873	potential frameshift: common BLAST hit: gi|67459496|ref|YP_247120.1| prolyl endopeptidase
1105111000874	coproporphyrinogen III oxidase; Provisional; Region: PRK06582
1105111000875	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105111000876	FeS/SAM binding site; other site
1105111000877	HemN C-terminal domain; Region: HemN_C; pfam06969
1105111000878	potential frameshift: common BLAST hit: gi|238650633|ref|YP_002916485.1| ankyrin repeat-containing protein
1105111000879	potential frameshift: common BLAST hit: gi|157826898|ref|YP_001495962.1| cephalosporin hydroxylase
1105111000880	potential frameshift: common BLAST hit: gi|157826898|ref|YP_001495962.1| cephalosporin hydroxylase
1105111000881	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1105111000882	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1105111000883	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1105111000884	Uncharacterized protein involved in tolerance to divalent cations [Inorganic ion transport and metabolism]; Region: CutA; COG1324
1105111000885	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
1105111000886	active site
1105111000887	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1105111000888	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1105111000889	E3 interaction surface; other site
1105111000890	lipoyl attachment site [posttranslational modification]; other site
1105111000891	e3 binding domain; Region: E3_binding; pfam02817
1105111000892	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1105111000893	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1105111000894	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1105111000895	TPP-binding site [chemical binding]; other site
1105111000896	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1105111000897	dimer interface [polypeptide binding]; other site
1105111000898	PYR/PP interface [polypeptide binding]; other site
1105111000899	TPP binding site [chemical binding]; other site
1105111000900	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
1105111000901	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
1105111000902	active site
1105111000903	Zn binding site [ion binding]; other site
1105111000904	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1105111000905	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1105111000906	Walker A/P-loop; other site
1105111000907	ATP binding site [chemical binding]; other site
1105111000908	Q-loop/lid; other site
1105111000909	Allexivirus 40kDa protein; Region: Allexi_40kDa; pfam05549
1105111000910	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1105111000911	ABC transporter signature motif; other site
1105111000912	Walker B; other site
1105111000913	D-loop; other site
1105111000914	H-loop/switch region; other site
1105111000915	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
1105111000916	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1105111000917	Putative cation transport regulator [General function prediction only]; Region: ChaB; COG4572
1105111000918	chaperone protein DnaJ; Provisional; Region: PRK14300
1105111000919	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1105111000920	HSP70 interaction site [polypeptide binding]; other site
1105111000921	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1105111000922	Zn binding sites [ion binding]; other site
1105111000923	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1105111000924	dimer interface [polypeptide binding]; other site
1105111000925	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1105111000926	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1105111000927	nucleotide binding site [chemical binding]; other site
1105111000928	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1105111000929	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1105111000930	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1105111000931	Lipopolysaccharide-assembly; Region: LptE; cl01125
1105111000932	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK06585
1105111000933	Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042
1105111000934	diiron binding motif [ion binding]; other site
1105111000935	Cytochrome c oxidase subunit III.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_III; cd01665
1105111000936	Subunit III/VIIa interface [polypeptide binding]; other site
1105111000937	Phospholipid binding site [chemical binding]; other site
1105111000938	Subunit I/III interface [polypeptide binding]; other site
1105111000939	Subunit III/VIb interface [polypeptide binding]; other site
1105111000940	Subunit III/VIa interface; other site
1105111000941	Subunit III/Vb interface [polypeptide binding]; other site
1105111000942	Type IV secretory pathway, VirB2 components (pilins) [Intracellular trafficking and secretion]; Region: VirB2; COG3838
1105111000943	MJ0042 family finger-like domain; Region: MJ0042_CXXC; TIGR02098
1105111000944	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1105111000945	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1105111000946	trimer interface [polypeptide binding]; other site
1105111000947	active site
1105111000948	substrate binding site [chemical binding]; other site
1105111000949	CoA binding site [chemical binding]; other site
1105111000950	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell envelope biogenesis, outer membrane]; Region: PbpC; COG4953
1105111000951	Transglycosylase; Region: Transgly; pfam00912
1105111000952	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1105111000953	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1105111000954	potential frameshift: common BLAST hit: gi|341583480|ref|YP_004763971.1| cell surface antigen-like protein Sca8
1105111000955	potential frameshift: common BLAST hit: gi|67459460|ref|YP_247084.1| cell surface antigen-like protein Sca8
1105111000956	potential frameshift: common BLAST hit: gi|67459460|ref|YP_247084.1| cell surface antigen-like protein Sca8
1105111000957	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1105111000958	Ligand Binding Site [chemical binding]; other site
1105111000959	TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: Imp; COG2358
1105111000960	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1105111000961	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1105111000962	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1105111000963	catalytic loop [active]
1105111000964	iron binding site [ion binding]; other site
1105111000965	chaperone protein HscA; Provisional; Region: hscA; PRK01433
1105111000966	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1105111000967	nucleotide binding site [chemical binding]; other site
1105111000968	co-chaperone HscB; Provisional; Region: hscB; PRK01356
1105111000969	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1105111000970	HSP70 interaction site [polypeptide binding]; other site
1105111000971	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1105111000972	RNA/DNA hybrid binding site [nucleotide binding]; other site
1105111000973	active site
1105111000974	excinuclease ABC subunit B; Provisional; Region: PRK05298
1105111000975	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105111000976	ATP binding site [chemical binding]; other site
1105111000977	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105111000978	nucleotide binding region [chemical binding]; other site
1105111000979	ATP-binding site [chemical binding]; other site
1105111000980	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1105111000981	UvrB/uvrC motif; Region: UVR; pfam02151
1105111000982	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1105111000983	GSH binding site [chemical binding]; other site
1105111000984	catalytic residues [active]
1105111000985	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
1105111000986	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105111000987	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
1105111000988	ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; Region: ABCC_ATM1_transporter; cd03253
1105111000989	Walker A/P-loop; other site
1105111000990	ATP binding site [chemical binding]; other site
1105111000991	Q-loop/lid; other site
1105111000992	ABC transporter signature motif; other site
1105111000993	Walker B; other site
1105111000994	D-loop; other site
1105111000995	H-loop/switch region; other site
1105111000996	DNA gyrase subunit A; Validated; Region: PRK05560
1105111000997	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1105111000998	CAP-like domain; other site
1105111000999	active site
1105111001000	primary dimer interface [polypeptide binding]; other site
1105111001001	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105111001002	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105111001003	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105111001004	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105111001005	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105111001006	potential frameshift: common BLAST hit: gi|67458714|ref|YP_246338.1| transporter
1105111001007	potential frameshift: common BLAST hit: gi|67458714|ref|YP_246338.1| transporter
1105111001008	Iron-sulphur cluster assembly; Region: Fe-S_assembly; cl01123
1105111001009	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1105111001010	active site
1105111001011	catalytic residues [active]
1105111001012	metal binding site [ion binding]; metal-binding site
1105111001013	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1105111001014	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1105111001015	putative active site [active]
1105111001016	substrate binding site [chemical binding]; other site
1105111001017	putative cosubstrate binding site; other site
1105111001018	catalytic site [active]
1105111001019	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1105111001020	substrate binding site [chemical binding]; other site
1105111001021	Predicted ATPase [General function prediction only]; Region: COG1485
1105111001022	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111001023	Walker A motif; other site
1105111001024	ATP binding site [chemical binding]; other site
1105111001025	Walker B motif; other site
1105111001026	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: PRK01424
1105111001027	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1105111001028	potential frameshift: common BLAST hit: gi|350273268|ref|YP_004884581.1| ankyrin
1105111001029	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1105111001030	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105111001031	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105111001032	Walker A/P-loop; other site
1105111001033	ATP binding site [chemical binding]; other site
1105111001034	Q-loop/lid; other site
1105111001035	ABC transporter signature motif; other site
1105111001036	Walker B; other site
1105111001037	D-loop; other site
1105111001038	H-loop/switch region; other site
1105111001039	Protein of unknown function (DUF2671); Region: DUF2671; pfam10877
1105111001040	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1105111001041	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1105111001042	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1105111001043	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
1105111001044	toxin-antitoxin system, toxin component, Txe/YoeB family; Region: toxin_Txe_YoeB; TIGR02116
1105111001045	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1105111001046	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1105111001047	putative metal binding site; other site
1105111001048	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1105111001049	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1105111001050	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1105111001051	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1105111001052	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1105111001053	ATP binding site [chemical binding]; other site
1105111001054	active site
1105111001055	substrate binding site [chemical binding]; other site
1105111001056	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1105111001057	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1105111001058	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1105111001059	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1105111001060	active site
1105111001061	dimer interface [polypeptide binding]; other site
1105111001062	motif 1; other site
1105111001063	motif 2; other site
1105111001064	motif 3; other site
1105111001065	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1105111001066	anticodon binding site; other site
1105111001067	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1105111001068	Protein of unknown function (DUF2660); Region: DUF2660; pfam10859
1105111001069	flagellar hook-associated protein FlgK; Region: flgK_ends; TIGR02492
1105111001070	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1105111001071	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3827
1105111001072	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105111001073	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1105111001074	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1105111001075	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105111001076	ATP binding site [chemical binding]; other site
1105111001077	Mg2+ binding site [ion binding]; other site
1105111001078	G-X-G motif; other site
1105111001079	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1105111001080	anchoring element; other site
1105111001081	dimer interface [polypeptide binding]; other site
1105111001082	ATP binding site [chemical binding]; other site
1105111001083	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1105111001084	active site
1105111001085	metal binding site [ion binding]; metal-binding site
1105111001086	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1105111001087	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1105111001088	C-terminal peptidase (prc); Region: prc; TIGR00225
1105111001089	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1105111001090	protein binding site [polypeptide binding]; other site
1105111001091	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1105111001092	Catalytic dyad [active]
1105111001093	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1105111001094	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105111001095	dimer interface [polypeptide binding]; other site
1105111001096	phosphorylation site [posttranslational modification]
1105111001097	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105111001098	ATP binding site [chemical binding]; other site
1105111001099	Mg2+ binding site [ion binding]; other site
1105111001100	G-X-G motif; other site
1105111001101	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1105111001102	Protein of unknown function (DUF2659); Region: DUF2659; pfam10858
1105111001103	FOG: WD40-like repeat [Function unknown]; Region: COG1520
1105111001104	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
1105111001105	Trp docking motif [polypeptide binding]; other site
1105111001106	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1105111001107	23S rRNA interface [nucleotide binding]; other site
1105111001108	L3 interface [polypeptide binding]; other site
1105111001109	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1105111001110	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
1105111001111	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111001112	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111001113	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH_subfamily_a; cd00913
1105111001114	aromatic arch; other site
1105111001115	DCoH dimer interaction site [polypeptide binding]; other site
1105111001116	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
1105111001117	DCoH tetramer interaction site [polypeptide binding]; other site
1105111001118	substrate binding site [chemical binding]; other site
1105111001119	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1105111001120	putative active site [active]
1105111001121	Ap4A binding site [chemical binding]; other site
1105111001122	nudix motif; other site
1105111001123	putative metal binding site [ion binding]; other site
1105111001124	response regulator PleD; Reviewed; Region: pleD; PRK09581
1105111001125	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105111001126	active site
1105111001127	phosphorylation site [posttranslational modification]
1105111001128	intermolecular recognition site; other site
1105111001129	dimerization interface [polypeptide binding]; other site
1105111001130	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105111001131	active site
1105111001132	phosphorylation site [posttranslational modification]
1105111001133	intermolecular recognition site; other site
1105111001134	dimerization interface [polypeptide binding]; other site
1105111001135	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1105111001136	metal binding site [ion binding]; metal-binding site
1105111001137	active site
1105111001138	I-site; other site
1105111001139	elongation factor P; Validated; Region: PRK00529
1105111001140	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1105111001141	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1105111001142	RNA binding site [nucleotide binding]; other site
1105111001143	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1105111001144	RNA binding site [nucleotide binding]; other site
1105111001145	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1105111001146	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
1105111001147	active site
1105111001148	Domain of unknown function (DUF2610); Region: DUF2610; pfam11020
1105111001149	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
1105111001150	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
1105111001151	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1105111001152	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1105111001153	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1105111001154	HlyD family secretion protein; Region: HlyD_3; pfam13437
1105111001155	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1105111001156	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
1105111001157	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1105111001158	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1105111001159	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1105111001160	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105111001161	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105111001162	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
1105111001163	FAD binding domain; Region: FAD_binding_4; pfam01565
1105111001164	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1105111001165	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1105111001166	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1105111001167	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1105111001168	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
1105111001169	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1105111001170	Cell division protein FtsQ; Region: FtsQ; pfam03799
1105111001171	cell division protein FtsA; Region: ftsA; TIGR01174
1105111001172	Cell division protein FtsA; Region: FtsA; smart00842
1105111001173	Cell division protein FtsA; Region: FtsA; pfam14450
1105111001174	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1105111001175	Cytochrome c2 [Energy production and conversion]; Region: COG3474
1105111001176	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1105111001177	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1105111001178	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105111001179	RNA binding site [nucleotide binding]; other site
1105111001180	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105111001181	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
1105111001182	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
1105111001183	Cytochrome oxidase assembly protein; Region: COX15-CtaA; cl15852
1105111001184	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1105111001185	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105111001186	RNA binding surface [nucleotide binding]; other site
1105111001187	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1105111001188	active site
1105111001189	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1105111001190	Beta-lactamase; Region: Beta-lactamase; pfam00144
1105111001191	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1105111001192	putative catalytic site [active]
1105111001193	putative phosphate binding site [ion binding]; other site
1105111001194	active site
1105111001195	metal binding site A [ion binding]; metal-binding site
1105111001196	DNA binding site [nucleotide binding]
1105111001197	putative AP binding site [nucleotide binding]; other site
1105111001198	putative metal binding site B [ion binding]; other site
1105111001199	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
1105111001200	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1105111001201	tetramer interface [polypeptide binding]; other site
1105111001202	TPP-binding site [chemical binding]; other site
1105111001203	heterodimer interface [polypeptide binding]; other site
1105111001204	phosphorylation loop region [posttranslational modification]
1105111001205	pyruvate dehydrogenase subunit beta; Validated; Region: PRK09212
1105111001206	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1105111001207	alpha subunit interface [polypeptide binding]; other site
1105111001208	TPP binding site [chemical binding]; other site
1105111001209	heterodimer interface [polypeptide binding]; other site
1105111001210	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1105111001211	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1105111001212	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1105111001213	G1 box; other site
1105111001214	putative GEF interaction site [polypeptide binding]; other site
1105111001215	GTP/Mg2+ binding site [chemical binding]; other site
1105111001216	Switch I region; other site
1105111001217	G2 box; other site
1105111001218	G3 box; other site
1105111001219	Switch II region; other site
1105111001220	G4 box; other site
1105111001221	G5 box; other site
1105111001222	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1105111001223	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1105111001224	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: HlpA; COG2825
1105111001225	isocitrate dehydrogenase; Validated; Region: PRK09222
1105111001226	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
1105111001227	monovalent cation/proton antiporter, MnhG/PhaG subunit; Region: CPA3_mnhG_phaG; TIGR01300
1105111001228	putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12507
1105111001229	Predicted subunit of the Multisubunit Na+/H+ antiporter [Inorganic ion transport and metabolism]; Region: COG1563
1105111001230	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
1105111001231	Protein of unknown function (DUF2670); Region: DUF2670; pfam10875
1105111001232	Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal; Region: UCR_Fe-S_N; pfam10399
1105111001233	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
1105111001234	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
1105111001235	[2Fe-2S] cluster binding site [ion binding]; other site
1105111001236	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
1105111001237	Qi binding site; other site
1105111001238	cytochrome b; Provisional; Region: CYTB; MTH00191
1105111001239	intrachain domain interface; other site
1105111001240	interchain domain interface [polypeptide binding]; other site
1105111001241	heme bH binding site [chemical binding]; other site
1105111001242	heme bL binding site [chemical binding]; other site
1105111001243	Qo binding site; other site
1105111001244	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cd00290
1105111001245	interchain domain interface [polypeptide binding]; other site
1105111001246	intrachain domain interface; other site
1105111001247	Qi binding site; other site
1105111001248	Qo binding site; other site
1105111001249	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cl15257
1105111001250	catalytic site [active]
1105111001251	metal binding site [ion binding]; metal-binding site
1105111001252	Cytochrome C1 family; Region: Cytochrom_C1; pfam02167
1105111001253	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1105111001254	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
1105111001255	putative dimer interface [polypeptide binding]; other site
1105111001256	PCRF domain; Region: PCRF; pfam03462
1105111001257	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1105111001258	RF-1 domain; Region: RF-1; pfam00472
1105111001259	GTP-binding protein LepA; Provisional; Region: PRK05433
1105111001260	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1105111001261	G1 box; other site
1105111001262	putative GEF interaction site [polypeptide binding]; other site
1105111001263	GTP/Mg2+ binding site [chemical binding]; other site
1105111001264	Switch I region; other site
1105111001265	G2 box; other site
1105111001266	G3 box; other site
1105111001267	Switch II region; other site
1105111001268	G4 box; other site
1105111001269	G5 box; other site
1105111001270	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1105111001271	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1105111001272	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1105111001273	Phage capsid family; Region: Phage_capsid; pfam05065
1105111001274	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1105111001275	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111001276	TPR motif; other site
1105111001277	TPR repeat; Region: TPR_11; pfam13414
1105111001278	binding surface
1105111001279	potential frameshift: common BLAST hit: gi|157964969|ref|YP_001499793.1| outer membrane protein OmpA
1105111001280	potential frameshift: common BLAST hit: gi|157964969|ref|YP_001499793.1| outer membrane protein OmpA
1105111001281	potential frameshift: common BLAST hit: gi|146302430|ref|YP_001197021.1| activator of Hsp90 ATPase 1 family protein
1105111001282	potential frameshift: common BLAST hit: gi|15892293|ref|NP_360007.1| ATP-dependent protease subunit C (ClpC)
1105111001283	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111001284	HD domain; Region: HD_4; pfam13328
1105111001285	HD domain; Region: HD_4; pfam13328
1105111001286	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111001287	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105111001288	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1105111001289	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
1105111001290	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105111001291	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1105111001292	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK06588
1105111001293	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105111001294	potential frameshift: common BLAST hit: gi|350273344|ref|YP_004884657.1| toxin of toxin-antitoxin VapC
1105111001295	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK06589
1105111001296	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105111001297	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK06591
1105111001298	putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK07375
1105111001299	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1105111001300	VirB7 interaction site; other site
1105111001301	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
1105111001302	Protein of unknown function (DUF2706); Region: DUF2706; pfam10913
1105111001303	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
1105111001304	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
1105111001305	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
1105111001306	type IV secretion system ATPase VirB11; Provisional; Region: PRK13900
1105111001307	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1105111001308	Walker A motif; other site
1105111001309	hexamer interface [polypeptide binding]; other site
1105111001310	ATP binding site [chemical binding]; other site
1105111001311	Walker B motif; other site
1105111001312	type IV secretion system component VirD4; Provisional; Region: PRK13897
1105111001313	The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome. They contain an ATP binding domain. VirD4 is involved in DNA transfer...; Region: TraG_VirD4; cd01126
1105111001314	Walker A motif; other site
1105111001315	ATP binding site [chemical binding]; other site
1105111001316	Walker B motif; other site
1105111001317	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
1105111001318	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1105111001319	Phage-related protein [Function unknown]; Region: COG4695; cl01923
1105111001320	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
1105111001321	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
1105111001322	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1105111001323	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1105111001324	active site
1105111001325	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1105111001326	MutS domain I; Region: MutS_I; pfam01624
1105111001327	MutS domain II; Region: MutS_II; pfam05188
1105111001328	MutS domain III; Region: MutS_III; pfam05192
1105111001329	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1105111001330	Walker A/P-loop; other site
1105111001331	ATP binding site [chemical binding]; other site
1105111001332	Q-loop/lid; other site
1105111001333	ABC transporter signature motif; other site
1105111001334	Walker B; other site
1105111001335	D-loop; other site
1105111001336	H-loop/switch region; other site
1105111001337	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
1105111001338	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1105111001339	Peptidase family M23; Region: Peptidase_M23; pfam01551
1105111001340	Protein of unknown function DUF45; Region: DUF45; pfam01863
1105111001341	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
1105111001342	translocation protein TolB; Provisional; Region: tolB; PRK05137
1105111001343	TolB amino-terminal domain; Region: TolB_N; pfam04052
1105111001344	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1105111001345	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1105111001346	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1105111001347	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1105111001348	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1105111001349	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1105111001350	DNA binding residues [nucleotide binding]
1105111001351	Cytochrome oxidase assembly factor [Posttranslational modification, protein turnover, chaperones]; Region: COX11; COG3175
1105111001352	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1105111001353	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1105111001354	Ligand Binding Site [chemical binding]; other site
1105111001355	amino acid transporter; Region: 2A0306; TIGR00909
1105111001356	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1105111001357	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1105111001358	dimer interface [polypeptide binding]; other site
1105111001359	motif 1; other site
1105111001360	active site
1105111001361	motif 2; other site
1105111001362	motif 3; other site
1105111001363	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1105111001364	anticodon binding site; other site
1105111001365	potential frameshift: common BLAST hit: gi|157827460|ref|YP_001496524.1| ABC transporter ATP-binding protein
1105111001366	potential frameshift: common BLAST hit: gi|67458892|ref|YP_246516.1| ABC transporter ATP-binding protein
1105111001367	TolQ protein; Region: tolQ; TIGR02796
1105111001368	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1105111001369	TolR protein; Region: tolR; TIGR02801
1105111001370	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111001371	HD domain; Region: HD_4; pfam13328
1105111001372	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111001373	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105111001374	putative substrate translocation pore; other site
1105111001375	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1105111001376	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
1105111001377	HlyD family secretion protein; Region: HlyD_3; pfam13437
1105111001378	type I secretion system ABC transporter, PrtD family; Region: type_I_sec_PrtD; TIGR01842
1105111001379	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105111001380	ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246
1105111001381	Walker A/P-loop; other site
1105111001382	ATP binding site [chemical binding]; other site
1105111001383	Q-loop/lid; other site
1105111001384	ABC transporter signature motif; other site
1105111001385	Walker B; other site
1105111001386	D-loop; other site
1105111001387	H-loop/switch region; other site
1105111001388	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1105111001389	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1105111001390	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
1105111001391	nucleotide binding site/active site [active]
1105111001392	HIT family signature motif; other site
1105111001393	catalytic residue [active]
1105111001394	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
1105111001395	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1105111001396	active site
1105111001397	HslU subunit interaction site [polypeptide binding]; other site
1105111001398	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1105111001399	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111001400	Walker A motif; other site
1105111001401	ATP binding site [chemical binding]; other site
1105111001402	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1105111001403	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1105111001404	potential frameshift: common BLAST hit: gi|91205630|ref|YP_537985.1| Mg chelatase-like protein
1105111001405	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105111001406	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1105111001407	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1105111001408	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105111001409	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
1105111001410	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1105111001411	dimerization interface [polypeptide binding]; other site
1105111001412	frataxin-like protein; Provisional; Region: cyaY; PRK01379
1105111001413	putative iron binding site [ion binding]; other site
1105111001414	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
1105111001415	glutamyl-tRNA synthetase; Provisional; Region: PRK12558
1105111001416	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1105111001417	HIGH motif; other site
1105111001418	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105111001419	active site
1105111001420	KMSKS motif; other site
1105111001421	DNA topoisomerase I; Validated; Region: PRK06599
1105111001422	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1105111001423	active site
1105111001424	interdomain interaction site; other site
1105111001425	putative metal-binding site [ion binding]; other site
1105111001426	nucleotide binding site [chemical binding]; other site
1105111001427	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1105111001428	domain I; other site
1105111001429	DNA binding groove [nucleotide binding]
1105111001430	phosphate binding site [ion binding]; other site
1105111001431	domain II; other site
1105111001432	domain III; other site
1105111001433	nucleotide binding site [chemical binding]; other site
1105111001434	catalytic site [active]
1105111001435	domain IV; other site
1105111001436	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1105111001437	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
1105111001438	potential frameshift: common BLAST hit: gi|67458923|ref|YP_246547.1| DNA processing protein DprA
1105111001439	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1105111001440	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1105111001441	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1105111001442	dimer interface [polypeptide binding]; other site
1105111001443	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1105111001444	catalytic triad [active]
1105111001445	peroxidatic and resolving cysteines [active]
1105111001446	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1105111001447	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1105111001448	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1105111001449	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1105111001450	Sulfatase; Region: Sulfatase; pfam00884
1105111001451	Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) [DNA replication, recombination, and repair]; Region: COG0816
1105111001452	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1105111001453	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105111001454	non-specific DNA binding site [nucleotide binding]; other site
1105111001455	salt bridge; other site
1105111001456	sequence-specific DNA binding site [nucleotide binding]; other site
1105111001457	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
1105111001458	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1105111001459	NADP binding site [chemical binding]; other site
1105111001460	active site
1105111001461	putative substrate binding site [chemical binding]; other site
1105111001462	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
1105111001463	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1105111001464	NAD(P) binding site [chemical binding]; other site
1105111001465	homodimer interface [polypeptide binding]; other site
1105111001466	substrate binding site [chemical binding]; other site
1105111001467	active site
1105111001468	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
1105111001469	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1105111001470	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1105111001471	active site
1105111001472	homodimer interface [polypeptide binding]; other site
1105111001473	potential frameshift: common BLAST hit: gi|238651057|ref|YP_002916914.1| methyltransferase
1105111001474	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1105111001475	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1105111001476	active site
1105111001477	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1105111001478	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1105111001479	active site
1105111001480	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
1105111001481	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1105111001482	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
1105111001483	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1105111001484	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1105111001485	catalytic site [active]
1105111001486	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1105111001487	This family is most closely related to the GT1 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core; Region: GT1_WavL_like; cd03819
1105111001488	putative ADP-binding pocket [chemical binding]; other site
1105111001489	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1105111001490	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1105111001491	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105111001492	RNA binding surface [nucleotide binding]; other site
1105111001493	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
1105111001494	UbiA prenyltransferase family; Region: UbiA; pfam01040
1105111001495	spore photoproduct lyase; Region: photo_TT_lyase; cl15393
1105111001496	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
1105111001497	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
1105111001498	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1105111001499	TPR motif; other site
1105111001500	binding surface
1105111001501	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1105111001502	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1105111001503	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1105111001504	RimM N-terminal domain; Region: RimM; pfam01782
1105111001505	PRC-barrel domain; Region: PRC; pfam05239
1105111001506	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1105111001507	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1105111001508	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5304
1105111001509	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
1105111001510	active site
1105111001511	DNA binding site [nucleotide binding]
1105111001512	YCII-related domain; Region: YCII; cl00999
1105111001513	hypothetical protein; Provisional; Region: PRK14388
1105111001514	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1105111001515	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1105111001516	putative dimer interface [polypeptide binding]; other site
1105111001517	[2Fe-2S] cluster binding site [ion binding]; other site
1105111001518	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
1105111001519	putative active site [active]
1105111001520	GIY-YIG motif/motif A; other site
1105111001521	putative metal binding site [ion binding]; other site
1105111001522	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
1105111001523	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1105111001524	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
1105111001525	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1105111001526	NADH dehydrogenase subunit B; Validated; Region: PRK06411
1105111001527	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1105111001528	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1105111001529	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4765
1105111001530	potential frameshift: common BLAST hit: gi|67458962|ref|YP_246586.1| phage protein
1105111001531	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1105111001532	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1105111001533	active site
1105111001534	DNA binding site [nucleotide binding]
1105111001535	Int/Topo IB signature motif; other site
1105111001536	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK06603
1105111001537	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1105111001538	NAD binding site [chemical binding]; other site
1105111001539	homotetramer interface [polypeptide binding]; other site
1105111001540	homodimer interface [polypeptide binding]; other site
1105111001541	substrate binding site [chemical binding]; other site
1105111001542	active site
1105111001543	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1105111001544	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1105111001545	putative active site [active]
1105111001546	catalytic triad [active]
1105111001547	putative dimer interface [polypeptide binding]; other site
1105111001548	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1105111001549	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1105111001550	substrate binding site [chemical binding]; other site
1105111001551	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG2984
1105111001552	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
1105111001553	TM-ABC transporter signature motif; other site
1105111001554	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
1105111001555	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105111001556	Walker A/P-loop; other site
1105111001557	ATP binding site [chemical binding]; other site
1105111001558	Q-loop/lid; other site
1105111001559	ABC transporter signature motif; other site
1105111001560	Walker B; other site
1105111001561	D-loop; other site
1105111001562	H-loop/switch region; other site
1105111001563	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105111001564	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105111001565	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105111001566	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1105111001567	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
1105111001568	lysyl-tRNA synthetase; Reviewed; Region: lysK; PRK00750
1105111001569	catalytic core domain of  class I lysyl tRNA synthetase; Region: LysRS_core_class_I; cd00674
1105111001570	active site
1105111001571	HIGH motif; other site
1105111001572	KMSKS motif; other site
1105111001573	Predicted permeases [General function prediction only]; Region: COG0679
1105111001574	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1105111001575	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1105111001576	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1105111001577	putative NAD(P) binding site [chemical binding]; other site
1105111001578	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1105111001579	potential frameshift: common BLAST hit: gi|165933089|ref|YP_001649878.1| protein transport protein SEC7
1105111001580	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
1105111001581	putative active site [active]
1105111001582	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105111001583	malate dehydrogenase; Reviewed; Region: PRK06223
1105111001584	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
1105111001585	NAD(P) binding site [chemical binding]; other site
1105111001586	dimer interface [polypeptide binding]; other site
1105111001587	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1105111001588	substrate binding site [chemical binding]; other site
1105111001589	potential frameshift: common BLAST hit: gi|67458983|ref|YP_246607.1| ankyrin repeat-containing protein
1105111001590	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105111001591	potential frameshift: common BLAST hit: gi|165933106|ref|YP_001649895.1| CTP synthetase
1105111001592	potential frameshift: common BLAST hit: gi|350273449|ref|YP_004884762.1| CTP synthetase
1105111001593	potential frameshift: common BLAST hit: gi|15892446|ref|NP_360160.1| CTP synthetase
1105111001594	potential frameshift: common BLAST hit: gi|341583751|ref|YP_004764242.1| CTP synthetase
1105111001595	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1105111001596	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1105111001597	Ligand binding site; other site
1105111001598	oligomer interface; other site
1105111001599	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_19; cd04678
1105111001600	nudix motif; other site
1105111001601	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
1105111001602	GTP cyclohydrolase I; Provisional; Region: PLN03044
1105111001603	active site
1105111001604	prolyl-tRNA synthetase; Provisional; Region: PRK12325
1105111001605	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1105111001606	dimer interface [polypeptide binding]; other site
1105111001607	motif 1; other site
1105111001608	active site
1105111001609	motif 2; other site
1105111001610	motif 3; other site
1105111001611	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1105111001612	anticodon binding site; other site
1105111001613	Fic family protein [Function unknown]; Region: COG3177
1105111001614	Fic/DOC family; Region: Fic; pfam02661
1105111001615	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1105111001616	RuvA N terminal domain; Region: RuvA_N; pfam01330
1105111001617	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1105111001618	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) [Translation, ribosomal structure and biogenesis]; Region: GatB; COG0064
1105111001619	Holliday junction resolvasome, helicase subunit [DNA replication, recombination, and repair]; Region: RuvB; COG2255
1105111001620	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111001621	Walker A motif; other site
1105111001622	ATP binding site [chemical binding]; other site
1105111001623	Walker B motif; other site
1105111001624	arginine finger; other site
1105111001625	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1105111001626	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1105111001627	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105111001628	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105111001629	Walker A/P-loop; other site
1105111001630	ATP binding site [chemical binding]; other site
1105111001631	Q-loop/lid; other site
1105111001632	ABC transporter signature motif; other site
1105111001633	Walker B; other site
1105111001634	D-loop; other site
1105111001635	H-loop/switch region; other site
1105111001636	Acetyl-coenzyme A transporter 1; Region: Acatn; pfam13000
1105111001637	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1105111001638	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111001639	putative substrate translocation pore; other site
1105111001640	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1105111001641	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1105111001642	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111001643	Rickettsial palindromic element RPE5 domain; Region: RPE5; TIGR03776
1105111001644	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1105111001645	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1105111001646	Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823
1105111001647	BON domain; Region: BON; pfam04972
1105111001648	BON domain; Region: BON; pfam04972
1105111001649	Intracellular septation protein A [Cell division and chromosome partitioning]; Region: COG2917
1105111001650	Iron permease FTR1 family; Region: FTR1; cl00475
1105111001651	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1105111001652	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1105111001653	Protocatechuate 3,4-dioxygenase beta subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PcaH; COG3485
1105111001654	Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208
1105111001655	active site
1105111001656	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1105111001657	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1105111001658	catalytic residues [active]
1105111001659	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
1105111001660	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1105111001661	tandem repeat interface [polypeptide binding]; other site
1105111001662	oligomer interface [polypeptide binding]; other site
1105111001663	active site residues [active]
1105111001664	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1105111001665	trimer interface [polypeptide binding]; other site
1105111001666	active site
1105111001667	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1105111001668	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1105111001669	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1105111001670	catalytic residue [active]
1105111001671	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1105111001672	dimer interface [polypeptide binding]; other site
1105111001673	catalytic triad [active]
1105111001674	Rickettsial palindromic element RPE4 domain; Region: RPE4; TIGR03777
1105111001675	RecB family exonuclease [DNA replication, recombination, and repair]; Region: COG2887
1105111001676	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1105111001677	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1105111001678	catalytic triad [active]
1105111001679	cytochrome c oxidase subunit I; Validated; Region: COX1; MTH00007
1105111001680	Cytochrome C oxidase subunit I.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_I; cd01663
1105111001681	Subunit I/III interface [polypeptide binding]; other site
1105111001682	D-pathway; other site
1105111001683	Subunit I/VIIc interface [polypeptide binding]; other site
1105111001684	Subunit I/IV interface [polypeptide binding]; other site
1105111001685	Subunit I/II interface [polypeptide binding]; other site
1105111001686	Low-spin heme (heme a) binding site [chemical binding]; other site
1105111001687	Subunit I/VIIa interface [polypeptide binding]; other site
1105111001688	Subunit I/VIa interface [polypeptide binding]; other site
1105111001689	Dimer interface; other site
1105111001690	Putative water exit pathway; other site
1105111001691	Binuclear center (heme a3/CuB) [ion binding]; other site
1105111001692	K-pathway; other site
1105111001693	Subunit I/Vb interface [polypeptide binding]; other site
1105111001694	Putative proton exit pathway; other site
1105111001695	Subunit I/VIb interface; other site
1105111001696	Subunit I/VIc interface [polypeptide binding]; other site
1105111001697	Electron transfer pathway; other site
1105111001698	Subunit I/VIIIb interface [polypeptide binding]; other site
1105111001699	Subunit I/VIIb interface [polypeptide binding]; other site
1105111001700	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1105111001701	active site
1105111001702	substrate binding site [chemical binding]; other site
1105111001703	trimer interface [polypeptide binding]; other site
1105111001704	CoA binding site [chemical binding]; other site
1105111001705	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111001706	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
1105111001707	cytochrome c oxidase subunit II; Provisional; Region: COX2; MTH00154
1105111001708	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1105111001709	putative peptidase; Provisional; Region: PRK11649
1105111001710	Peptidase family M23; Region: Peptidase_M23; pfam01551
1105111001711	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1105111001712	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1105111001713	Protein of unknown function (DUF3035); Region: DUF3035; pfam11233
1105111001714	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01368
1105111001715	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105111001716	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105111001717	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105111001718	cell division protein FtsW; Region: ftsW; TIGR02614
1105111001719	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1105111001720	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1105111001721	active site
1105111001722	homodimer interface [polypeptide binding]; other site
1105111001723	potential frameshift: common BLAST hit: gi|67459031|ref|YP_246655.1| RND family efflux transporter
1105111001724	potential frameshift: common BLAST hit: gi|157827177|ref|YP_001496241.1| RND family efflux transporter
1105111001725	potential frameshift: common BLAST hit: gi|157827177|ref|YP_001496241.1| RND family efflux transporter
1105111001726	potential frameshift: common BLAST hit: gi|67459033|ref|YP_246657.1| RND family efflux transporter
1105111001727	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1105111001728	HlyD family secretion protein; Region: HlyD_3; pfam13437
1105111001729	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1105111001730	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1105111001731	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1105111001732	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105111001733	diaminopimelate epimerase; Region: DapF; TIGR00652
1105111001734	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1105111001735	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1105111001736	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1105111001737	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1105111001738	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105111001739	FeS/SAM binding site; other site
1105111001740	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1105111001741	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1105111001742	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1105111001743	dimer interface [polypeptide binding]; other site
1105111001744	motif 1; other site
1105111001745	active site
1105111001746	motif 2; other site
1105111001747	motif 3; other site
1105111001748	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1105111001749	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1105111001750	putative tRNA-binding site [nucleotide binding]; other site
1105111001751	B3/4 domain; Region: B3_4; pfam03483
1105111001752	tRNA synthetase B5 domain; Region: B5; smart00874
1105111001753	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1105111001754	dimer interface [polypeptide binding]; other site
1105111001755	motif 1; other site
1105111001756	motif 3; other site
1105111001757	motif 2; other site
1105111001758	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1105111001759	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1105111001760	DNA polymerase III subunit beta; Validated; Region: PRK05643
1105111001761	putative DNA binding surface [nucleotide binding]; other site
1105111001762	dimer interface [polypeptide binding]; other site
1105111001763	beta-clamp/clamp loader binding surface; other site
1105111001764	beta-clamp/translesion DNA polymerase binding surface; other site
1105111001765	Protein of unknown function (DUF1653); Region: DUF1653; pfam07866
1105111001766	Domain of unknown function (DUF3576); Region: DUF3576; pfam12100
1105111001767	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1105111001768	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1105111001769	HIGH motif; other site
1105111001770	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1105111001771	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105111001772	active site
1105111001773	KMSKS motif; other site
1105111001774	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1105111001775	tRNA binding surface [nucleotide binding]; other site
1105111001776	Rickettsial palindromic element RPE5 domain; Region: RPE5; TIGR03776
1105111001777	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
1105111001778	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1105111001779	catalytic site [active]
1105111001780	putative active site [active]
1105111001781	putative substrate binding site [chemical binding]; other site
1105111001782	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1105111001783	Septum formation initiator; Region: DivIC; pfam04977
1105111001784	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1105111001785	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1105111001786	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
1105111001787	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
1105111001788	catalytic residue [active]
1105111001789	putative FPP diphosphate  binding site; other site
1105111001790	putative FPP binding hydrophobic cleft; other site
1105111001791	dimer interface [polypeptide binding]; other site
1105111001792	putative IPP diphosphate binding site; other site
1105111001793	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105111001794	HAMP domain; Region: HAMP; pfam00672
1105111001795	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105111001796	dimer interface [polypeptide binding]; other site
1105111001797	phosphorylation site [posttranslational modification]
1105111001798	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105111001799	ATP binding site [chemical binding]; other site
1105111001800	Mg2+ binding site [ion binding]; other site
1105111001801	G-X-G motif; other site
1105111001802	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1105111001803	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105111001804	active site
1105111001805	phosphorylation site [posttranslational modification]
1105111001806	intermolecular recognition site; other site
1105111001807	dimerization interface [polypeptide binding]; other site
1105111001808	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1105111001809	DNA binding site [nucleotide binding]
1105111001810	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
1105111001811	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1105111001812	homodimer interface [polypeptide binding]; other site
1105111001813	substrate-cofactor binding pocket; other site
1105111001814	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105111001815	catalytic residue [active]
1105111001816	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1105111001817	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1105111001818	dimer interface [polypeptide binding]; other site
1105111001819	active site
1105111001820	catalytic residue [active]
1105111001821	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1105111001822	SmpB-tmRNA interface; other site
1105111001823	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1105111001824	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1105111001825	catalytic residues [active]
1105111001826	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1105111001827	CoA binding domain; Region: CoA_binding; pfam02629
1105111001828	CoA-ligase; Region: Ligase_CoA; pfam00549
1105111001829	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1105111001830	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1105111001831	CoA-ligase; Region: Ligase_CoA; pfam00549
1105111001832	potential frameshift: common BLAST hit: gi|374319289|ref|YP_005065788.1| Putative nucleic-acid-binding protein, containing PIN domain
1105111001833	potential frameshift: common BLAST hit: gi|165933193|ref|YP_001649982.1| cytochrome b561
1105111001834	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1105111001835	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1105111001836	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4395
1105111001837	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1105111001838	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1105111001839	Predicted membrane protein [Function unknown]; Region: COG1238
1105111001840	Predicted membrane protein/domain [Function unknown]; Region: COG1714
1105111001841	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
1105111001842	RecR protein; Region: RecR; pfam02132
1105111001843	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1105111001844	putative active site [active]
1105111001845	putative metal-binding site [ion binding]; other site
1105111001846	tetramer interface [polypeptide binding]; other site
1105111001847	inorganic polyphosphate/ATP-NAD kinase; Reviewed; Region: ppnK; PRK04761
1105111001848	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1105111001849	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1105111001850	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1105111001851	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1105111001852	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1105111001853	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1105111001854	Predicted permeases [General function prediction only]; Region: COG0679
1105111001855	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1105111001856	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1105111001857	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1105111001858	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105111001859	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1105111001860	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1105111001861	tetramerization interface [polypeptide binding]; other site
1105111001862	NAD(P) binding site [chemical binding]; other site
1105111001863	catalytic residues [active]
1105111001864	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1105111001865	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1105111001866	active site
1105111001867	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1105111001868	Part of AAA domain; Region: AAA_19; pfam13245
1105111001869	Family description; Region: UvrD_C_2; pfam13538
1105111001870	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1105111001871	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1105111001872	tetramer interface [polypeptide binding]; other site
1105111001873	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105111001874	catalytic residue [active]
1105111001875	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1105111001876	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1105111001877	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111001878	Walker A motif; other site
1105111001879	ATP binding site [chemical binding]; other site
1105111001880	Walker B motif; other site
1105111001881	arginine finger; other site
1105111001882	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1105111001883	potential frameshift: common BLAST hit: gi|67459085|ref|YP_246709.1| cell surface antigen Sca3
1105111001884	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1105111001885	30S subunit binding site; other site
1105111001886	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1105111001887	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1105111001888	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14171
1105111001889	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1105111001890	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1105111001891	homodimer interface [polypeptide binding]; other site
1105111001892	NADP binding site [chemical binding]; other site
1105111001893	substrate binding site [chemical binding]; other site
1105111001894	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1105111001895	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1105111001896	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105111001897	potential frameshift: common BLAST hit: gi|165933233|ref|YP_001650022.1| protein U
1105111001898	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1105111001899	potential frameshift: common BLAST hit: gi|157827080|ref|YP_001496144.1| P pilus assembly, fimbrial usher protein
1105111001900	potential frameshift: common BLAST hit: gi|67459098|ref|YP_246722.1| P pilus assembly protein FimD
1105111001901	potential frameshift: common BLAST hit: gi|67459098|ref|YP_246722.1| P pilus assembly protein FimD
1105111001902	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09102
1105111001903	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1105111001904	active site
1105111001905	dimer interface [polypeptide binding]; other site
1105111001906	catalytic residues [active]
1105111001907	effector binding site; other site
1105111001908	R2 peptide binding site; other site
1105111001909	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1105111001910	dimer interface [polypeptide binding]; other site
1105111001911	putative radical transfer pathway; other site
1105111001912	diiron center [ion binding]; other site
1105111001913	tyrosyl radical; other site
1105111001914	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1105111001915	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1105111001916	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1105111001917	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1105111001918	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1105111001919	active site
1105111001920	substrate binding site [chemical binding]; other site
1105111001921	metal binding site [ion binding]; metal-binding site
1105111001922	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1105111001923	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1105111001924	Walker A/P-loop; other site
1105111001925	ATP binding site [chemical binding]; other site
1105111001926	Q-loop/lid; other site
1105111001927	ABC transporter signature motif; other site
1105111001928	Walker B; other site
1105111001929	D-loop; other site
1105111001930	H-loop/switch region; other site
1105111001931	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111001932	OstA-like protein; Region: OstA; pfam03968
1105111001933	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5375
1105111001934	KpsF/GutQ family protein; Region: kpsF; TIGR00393
1105111001935	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1105111001936	putative active site [active]
1105111001937	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1105111001938	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1105111001939	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1105111001940	RNase E interface [polypeptide binding]; other site
1105111001941	trimer interface [polypeptide binding]; other site
1105111001942	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1105111001943	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1105111001944	RNase E interface [polypeptide binding]; other site
1105111001945	trimer interface [polypeptide binding]; other site
1105111001946	active site
1105111001947	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1105111001948	putative nucleic acid binding region [nucleotide binding]; other site
1105111001949	G-X-X-G motif; other site
1105111001950	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1105111001951	RNA binding site [nucleotide binding]; other site
1105111001952	domain interface; other site
1105111001953	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1105111001954	16S/18S rRNA binding site [nucleotide binding]; other site
1105111001955	S13e-L30e interaction site [polypeptide binding]; other site
1105111001956	25S rRNA binding site [nucleotide binding]; other site
1105111001957	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK14846
1105111001958	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1105111001959	RNA binding site [nucleotide binding]; other site
1105111001960	active site
1105111001961	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111001962	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105111001963	120 KDa Rickettsia surface antigen; Region: 120_Rick_ant; pfam12574
1105111001964	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1105111001965	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105111001966	non-specific DNA binding site [nucleotide binding]; other site
1105111001967	salt bridge; other site
1105111001968	sequence-specific DNA binding site [nucleotide binding]; other site
1105111001969	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
1105111001970	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1105111001971	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1105111001972	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1105111001973	uncharacterized protein, YfiH family; Region: TIGR00726
1105111001974	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1105111001975	active site
1105111001976	catalytic residues [active]
1105111001977	metal binding site [ion binding]; metal-binding site
1105111001978	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
1105111001979	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
1105111001980	putative active site [active]
1105111001981	homotetrameric interface [polypeptide binding]; other site
1105111001982	metal binding site [ion binding]; metal-binding site
1105111001983	potential frameshift: common BLAST hit: gi|374319343|ref|YP_005065842.1| Erythrocyte adducin alpha subunit
1105111001984	pyruvate phosphate dikinase; Provisional; Region: PRK09279
1105111001985	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1105111001986	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1105111001987	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1105111001988	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1105111001989	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1105111001990	GSH binding site (G-site) [chemical binding]; other site
1105111001991	C-terminal domain interface [polypeptide binding]; other site
1105111001992	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cd00299
1105111001993	N-terminal domain interface [polypeptide binding]; other site
1105111001994	dimer interface [polypeptide binding]; other site
1105111001995	substrate binding pocket (H-site) [chemical binding]; other site
1105111001996	COG4285 Uncharacterized conserved protein
1105111001997	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
1105111001998	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1105111001999	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1105111002000	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1105111002001	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1105111002002	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1105111002003	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
1105111002004	active site
1105111002005	nucleophile elbow; other site
1105111002006	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1105111002007	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1105111002008	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1105111002009	potential frameshift: common BLAST hit: gi|91205124|ref|YP_537479.1| Phage prohead protease and phage major capsid protein
1105111002010	potential frameshift: common BLAST hit: gi|67459141|ref|YP_246765.1| HK97 family phage prohead protease/phage major capsid protein
1105111002011	potential frameshift: common BLAST hit: gi|157827542|ref|YP_001496606.1| Phage prohead protease and phage major capsid protein
1105111002012	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
1105111002013	Nucleotidyltransferase substrate binding protein like; Region: NTase_sub_bind; pfam08780
1105111002014	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1105111002015	active site
1105111002016	NTP binding site [chemical binding]; other site
1105111002017	metal binding triad [ion binding]; metal-binding site
1105111002018	antibiotic binding site [chemical binding]; other site
1105111002019	Conserved hypothetical protein 2217 (DUF2460); Region: DUF2460; cl02268
1105111002020	Uncharacterized conserved protein (DUF2163); Region: DUF2163; pfam09931
1105111002021	Phage conserved hypothetical protein BR0599; Region: Phage_BR0599; pfam09356
1105111002022	Predicted membrane protein [Function unknown]; Region: COG5346
1105111002023	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1105111002024	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1105111002025	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1105111002026	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1105111002027	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; Region: PDHac_trf_mito; TIGR01349
1105111002028	E3 interaction surface; other site
1105111002029	lipoyl attachment site [posttranslational modification]; other site
1105111002030	e3 binding domain; Region: E3_binding; pfam02817
1105111002031	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1105111002032	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1105111002033	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1105111002034	RF-1 domain; Region: RF-1; pfam00472
1105111002035	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1105111002036	DHH family; Region: DHH; pfam01368
1105111002037	DHHA1 domain; Region: DHHA1; pfam02272
1105111002038	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105111002039	S-adenosylmethionine binding site [chemical binding]; other site
1105111002040	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1105111002041	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1105111002042	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1105111002043	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1105111002044	RNA binding site [nucleotide binding]; other site
1105111002045	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1105111002046	multimer interface [polypeptide binding]; other site
1105111002047	Walker A motif; other site
1105111002048	ATP binding site [chemical binding]; other site
1105111002049	Walker B motif; other site
1105111002050	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1105111002051	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1105111002052	tandem repeat interface [polypeptide binding]; other site
1105111002053	oligomer interface [polypeptide binding]; other site
1105111002054	active site residues [active]
1105111002055	Bacterial nucleoid DNA-binding protein [DNA replication, recombination, and repair]; Region: HimA; COG0776
1105111002056	IHF - DNA interface [nucleotide binding]; other site
1105111002057	IHF dimer interface [polypeptide binding]; other site
1105111002058	potential frameshift: common BLAST hit: gi|341583918|ref|YP_004764409.1| putative cytoplasmic protein
1105111002059	potential frameshift: common BLAST hit: gi|341583918|ref|YP_004764409.1| putative cytoplasmic protein
1105111002060	potential frameshift: common BLAST hit: gi|157827404|ref|YP_001496468.1| integrase
1105111002061	potential frameshift: common BLAST hit: gi|157964586|ref|YP_001499410.1| integrase
1105111002062	Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170
1105111002063	PLD-like domain; Region: PLDc_2; pfam13091
1105111002064	putative active site [active]
1105111002065	catalytic site [active]
1105111002066	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1105111002067	Na binding site [ion binding]; other site
1105111002068	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111002069	HD domain; Region: HD_4; pfam13328
1105111002070	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1105111002071	MULE transposase domain; Region: MULE; pfam10551
1105111002072	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111002073	TPR motif; other site
1105111002074	TPR repeat; Region: TPR_11; pfam13414
1105111002075	binding surface
1105111002076	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111002077	binding surface
1105111002078	TPR motif; other site
1105111002079	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1105111002080	potential frameshift: common BLAST hit: gi|157827423|ref|YP_001496487.1| conjugative transfer protein TraD
1105111002081	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105111002082	Conjugal transfer protein TraD; Region: TraD; pfam06412
1105111002083	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111002084	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1105111002085	synthetase active site [active]
1105111002086	NTP binding site [chemical binding]; other site
1105111002087	metal binding site [ion binding]; metal-binding site
1105111002088	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
1105111002089	DNA binding residues [nucleotide binding]
1105111002090	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111002091	HD domain; Region: HD_4; pfam13328
1105111002092	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1105111002093	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1105111002094	dimer interface [polypeptide binding]; other site
1105111002095	phosphorylation site [posttranslational modification]
1105111002096	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105111002097	ATP binding site [chemical binding]; other site
1105111002098	Mg2+ binding site [ion binding]; other site
1105111002099	G-X-G motif; other site
1105111002100	TraX protein; Region: TraX; pfam05857
1105111002101	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111002102	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1105111002103	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1105111002104	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1105111002105	dimer interface [polypeptide binding]; other site
1105111002106	substrate binding site [chemical binding]; other site
1105111002107	metal binding sites [ion binding]; metal-binding site
1105111002108	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13254
1105111002109	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
1105111002110	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1105111002111	Cu(I) binding site [ion binding]; other site
1105111002112	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1105111002113	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1105111002114	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1105111002115	Rickettsial palindromic element RPE5 domain; Region: RPE5; TIGR03776
1105111002116	Predicted DNA-binding protein with an HTH domain [General function prediction only]; Region: COG4710
1105111002117	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111002118	HD domain; Region: HD_4; pfam13328
1105111002119	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1105111002120	MgtE intracellular N domain; Region: MgtE_N; pfam03448
1105111002121	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1105111002122	Divalent cation transporter; Region: MgtE; pfam01769
1105111002123	HAD-superfamily class IIA hydrolase, TIGR01459; Region: HAD-SF-IIA-hyp4
1105111002124	Haloacid dehalogenase-like hydrolase; Region: Hydrolase_6; pfam13344
1105111002125	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1105111002126	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1105111002127	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105111002128	ATP binding site [chemical binding]; other site
1105111002129	Mg2+ binding site [ion binding]; other site
1105111002130	G-X-G motif; other site
1105111002131	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1105111002132	anchoring element; other site
1105111002133	dimer interface [polypeptide binding]; other site
1105111002134	ATP binding site [chemical binding]; other site
1105111002135	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1105111002136	active site
1105111002137	putative metal-binding site [ion binding]; other site
1105111002138	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1105111002139	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1105111002140	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1105111002141	hinge; other site
1105111002142	active site
1105111002143	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1105111002144	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1105111002145	peptidylprolyl isomerase; Reviewed; Region: prsA; PRK03095
1105111002146	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1105111002147	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1105111002148	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1105111002149	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1105111002150	SEC-C motif; Region: SEC-C; pfam02810
1105111002151	potential frameshift: common BLAST hit: gi|67459332|ref|YP_246956.1| nucleotidyltransferase/HEPN domain-containing protein
1105111002152	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1105111002153	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1105111002154	potential frameshift: common BLAST hit: gi|91205217|ref|YP_537572.1| Type I site-specific restriction-modification system, R
1105111002155	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1105111002156	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1105111002157	DNA binding site [nucleotide binding]
1105111002158	active site
1105111002159	potential frameshift: common BLAST hit: gi|15892791|ref|NP_360505.1| methylated-DNA--protein-cysteine methyltransferase
1105111002160	potential frameshift: common BLAST hit: gi|341584048|ref|YP_004764539.1| methylated-DNA--protein-cysteine methyltransferase
1105111002161	A new structural DNA glycosylase; Region: AlkD_like; cl11434
1105111002162	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
1105111002163	A new structural DNA glycosylase; Region: AlkD_like; cd06561
1105111002164	active site
1105111002165	Copper(I)-binding protein [Inorganic ion transport and    metabolism]; Region: COG2847
1105111002166	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1105111002167	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1105111002168	GIY-YIG motif/motif A; other site
1105111002169	active site
1105111002170	catalytic site [active]
1105111002171	putative DNA binding site [nucleotide binding]; other site
1105111002172	metal binding site [ion binding]; metal-binding site
1105111002173	UvrB/uvrC motif; Region: UVR; pfam02151
1105111002174	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1105111002175	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1105111002176	Na binding site [ion binding]; other site
1105111002177	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2001
1105111002178	MraZ protein; Region: MraZ; pfam02381
1105111002179	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1105111002180	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105111002181	S-adenosylmethionine binding site [chemical binding]; other site
1105111002182	Predicted secreted (periplasmic) protein [Function unknown]; Region: COG5462
1105111002183	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1105111002184	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1105111002185	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1105111002186	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1105111002187	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1105111002188	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1105111002189	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: COG3264
1105111002190	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1105111002191	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1105111002192	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1105111002193	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105111002194	active site
1105111002195	phosphorylation site [posttranslational modification]
1105111002196	intermolecular recognition site; other site
1105111002197	dimerization interface [polypeptide binding]; other site
1105111002198	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111002199	Walker A motif; other site
1105111002200	ATP binding site [chemical binding]; other site
1105111002201	Walker B motif; other site
1105111002202	arginine finger; other site
1105111002203	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1105111002204	putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK12612
1105111002205	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111002206	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK06617
1105111002207	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1105111002208	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1105111002209	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1105111002210	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
1105111002211	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1105111002212	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1105111002213	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1105111002214	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
1105111002215	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1105111002216	substrate binding site [chemical binding]; other site
1105111002217	oxyanion hole (OAH) forming residues; other site
1105111002218	trimer interface [polypeptide binding]; other site
1105111002219	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1105111002220	MG2 domain; Region: A2M_N; pfam01835
1105111002221	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1105111002222	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1105111002223	surface patch; other site
1105111002224	thioester region; other site
1105111002225	specificity defining residues; other site
1105111002226	potential frameshift: common BLAST hit: gi|157826964|ref|YP_001496028.1| proline/betaine transporter
1105111002227	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1105111002228	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5304
1105111002229	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1105111002230	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1105111002231	active site
1105111002232	HIGH motif; other site
1105111002233	dimer interface [polypeptide binding]; other site
1105111002234	KMSKS motif; other site
1105111002235	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105111002236	RNA binding surface [nucleotide binding]; other site
1105111002237	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1105111002238	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105111002239	RNA binding surface [nucleotide binding]; other site
1105111002240	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1105111002241	Predicted transcriptional regulator [Transcription]; Region: COG1959
1105111002242	Transcriptional regulator; Region: Rrf2; cl17282
1105111002243	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
1105111002244	Sm and related proteins; Region: Sm_like; cl00259
1105111002245	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1105111002246	putative oligomer interface [polypeptide binding]; other site
1105111002247	putative RNA binding site [nucleotide binding]; other site
1105111002248	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1105111002249	NusA N-terminal domain; Region: NusA_N; pfam08529
1105111002250	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1105111002251	RNA binding site [nucleotide binding]; other site
1105111002252	homodimer interface [polypeptide binding]; other site
1105111002253	NusA-like KH domain; Region: KH_5; pfam13184
1105111002254	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1105111002255	G-X-X-G motif; other site
1105111002256	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1105111002257	translation initiation factor IF-2; Validated; Region: infB; PRK05306
1105111002258	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1105111002259	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1105111002260	G1 box; other site
1105111002261	putative GEF interaction site [polypeptide binding]; other site
1105111002262	GTP/Mg2+ binding site [chemical binding]; other site
1105111002263	Switch I region; other site
1105111002264	G2 box; other site
1105111002265	G3 box; other site
1105111002266	Switch II region; other site
1105111002267	G4 box; other site
1105111002268	G5 box; other site
1105111002269	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1105111002270	Translation-initiation factor 2; Region: IF-2; pfam11987
1105111002271	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1105111002272	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1105111002273	Glycoprotease family; Region: Peptidase_M22; pfam00814
1105111002274	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1105111002275	Recombination protein O N terminal; Region: RecO_N; pfam11967
1105111002276	Recombination protein O C terminal; Region: RecO_C; pfam02565
1105111002277	DNA repair protein RadA; Provisional; Region: PRK11823
1105111002278	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1105111002279	Walker A motif/ATP binding site; other site
1105111002280	ATP binding site [chemical binding]; other site
1105111002281	Walker B motif; other site
1105111002282	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1105111002283	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1105111002284	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105111002285	S-adenosylmethionine binding site [chemical binding]; other site
1105111002286	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1105111002287	Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576
1105111002288	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1105111002289	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1105111002290	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1105111002291	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1105111002292	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105111002293	RNA binding surface [nucleotide binding]; other site
1105111002294	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1105111002295	active site
1105111002296	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1105111002297	potential frameshift: common BLAST hit: gi|67459254|ref|YP_246878.1| to amino acid permeases
1105111002298	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1105111002299	replicative DNA helicase; Provisional; Region: PRK09165
1105111002300	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1105111002301	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1105111002302	Walker A motif; other site
1105111002303	ATP binding site [chemical binding]; other site
1105111002304	Walker B motif; other site
1105111002305	DNA binding loops [nucleotide binding]
1105111002306	polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases; Region: ubiX_pad; TIGR00421
1105111002307	Flavoprotein; Region: Flavoprotein; pfam02441
1105111002308	primosome assembly protein PriA; Validated; Region: PRK05580
1105111002309	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105111002310	ATP binding site [chemical binding]; other site
1105111002311	putative Mg++ binding site [ion binding]; other site
1105111002312	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1105111002313	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
1105111002314	dimer interface [polypeptide binding]; other site
1105111002315	allosteric magnesium binding site [ion binding]; other site
1105111002316	active site
1105111002317	aspartate-rich active site metal binding site; other site
1105111002318	Schiff base residues; other site
1105111002319	NADH dehydrogenase subunit 2; Provisional; Region: ND2; MTH00196
1105111002320	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105111002321	potential frameshift: common BLAST hit: gi|67459245|ref|YP_246869.1| NTPase
1105111002322	potential frameshift: common BLAST hit: gi|67458839|ref|YP_246463.1| NACHT domain-containing protein
1105111002323	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105111002324	Predicted transcriptional regulator [Transcription]; Region: COG1959
1105111002325	iron-sulfur cluster assembly transcription factor IscR; Region: IscR; TIGR02010
1105111002326	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1105111002327	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1105111002328	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1105111002329	catalytic residue [active]
1105111002330	cysteine desulfurase; Provisional; Region: PRK14012
1105111002331	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1105111002332	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1105111002333	catalytic residue [active]
1105111002334	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1105111002335	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1105111002336	trimerization site [polypeptide binding]; other site
1105111002337	active site
1105111002338	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1105111002339	arginine:agmatin antiporter; Provisional; Region: PRK10644
1105111002340	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1105111002341	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1105111002342	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111002343	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
1105111002344	active site
1105111002345	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1105111002346	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1105111002347	substrate binding pocket [chemical binding]; other site
1105111002348	chain length determination region; other site
1105111002349	substrate-Mg2+ binding site; other site
1105111002350	catalytic residues [active]
1105111002351	aspartate-rich region 1; other site
1105111002352	active site lid residues [active]
1105111002353	aspartate-rich region 2; other site
1105111002354	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105111002355	muropeptide transporter; Validated; Region: ampG; cl17669
1105111002356	muropeptide transporter; Validated; Region: ampG; cl17669
1105111002357	Lysine efflux permease [General function prediction only]; Region: COG1279
1105111002358	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1105111002359	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1105111002360	active site
1105111002361	Rickettsial palindromic element RPE2 domain; Region: RPE2; TIGR03774
1105111002362	HemY protein N-terminus; Region: HemY_N; pfam07219
1105111002363	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
1105111002364	Serine hydrolase (FSH1); Region: FSH1; pfam03959
1105111002365	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
1105111002366	Protein required for attachment to host cells; Region: Host_attach; cl02398
1105111002367	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1105111002368	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1105111002369	putative acyl-acceptor binding pocket; other site
1105111002370	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1105111002371	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1105111002372	active site
1105111002373	HIGH motif; other site
1105111002374	dimer interface [polypeptide binding]; other site
1105111002375	KMSKS motif; other site
1105111002376	AAA domain; Region: AAA_14; pfam13173
1105111002377	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1105111002378	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1105111002379	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1105111002380	domain interfaces; other site
1105111002381	active site
1105111002382	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105111002383	ATP binding site [chemical binding]; other site
1105111002384	G-X-G motif; other site
1105111002385	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105111002386	dimer interface [polypeptide binding]; other site
1105111002387	phosphorylation site [posttranslational modification]
1105111002388	potential frameshift: common BLAST hit: gi|15892625|ref|NP_360339.1| sodium/pantothenate symporter
1105111002389	potential frameshift: common BLAST hit: gi|157964645|ref|YP_001499469.1| ankyrin repeat-containing protein
1105111002390	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
1105111002391	Rickettsial palindromic element RPE2 domain; Region: RPE2; TIGR03774
1105111002392	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1105111002393	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1105111002394	Uncharacterized conserved protein [Function unknown]; Region: COG1723
1105111002395	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
1105111002396	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1105111002397	catalytic site [active]
1105111002398	putative active site [active]
1105111002399	putative substrate binding site [chemical binding]; other site
1105111002400	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1105111002401	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
1105111002402	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1105111002403	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
1105111002404	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1105111002405	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105111002406	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1105111002407	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1105111002408	S-adenosylmethionine binding site [chemical binding]; other site
1105111002409	Methyltransferase domain; Region: Methyltransf_11; pfam08241
1105111002410	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1105111002411	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1105111002412	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1105111002413	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
1105111002414	Protein of unknown function (DUF2532); Region: DUF2532; pfam10811
1105111002415	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1105111002416	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1105111002417	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1105111002418	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1105111002419	hypothetical protein; Validated; Region: PRK00110
1105111002420	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1105111002421	Substrate binding site; other site
1105111002422	Mg++ binding site; other site
1105111002423	Domain of unknown function (DUF4415); Region: DUF4415; cl01401
1105111002424	Protein of unknown function (DUF497); Region: DUF497; cl01108
1105111002425	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1105111002426	homodimer interface [polypeptide binding]; other site
1105111002427	active site
1105111002428	putative chemical substrate binding site [chemical binding]; other site
1105111002429	metal binding site [ion binding]; metal-binding site
1105111002430	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1105111002431	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1105111002432	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1105111002433	CoA binding site [chemical binding]; other site
1105111002434	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1105111002435	Coenzyme A binding pocket [chemical binding]; other site
1105111002436	Predicted acetyltransferase [General function prediction only]; Region: COG5628
1105111002437	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
1105111002438	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
1105111002439	homotetramer interface [polypeptide binding]; other site
1105111002440	FMN binding site [chemical binding]; other site
1105111002441	homodimer contacts [polypeptide binding]; other site
1105111002442	putative active site [active]
1105111002443	putative substrate binding site [chemical binding]; other site
1105111002444	potential frameshift: common BLAST hit: gi|67459167|ref|YP_246791.1| acetyltransferase
1105111002445	potential frameshift: common BLAST hit: gi|379713793|ref|YP_005302131.1| streptomycin 6-kinase
1105111002446	Aminoglycoside/hydroxyurea antibiotic resistance kinase; Region: APH_6_hur; cl17810
1105111002447	potential frameshift: common BLAST hit: gi|67459165|ref|YP_246789.1| transcription activator
1105111002448	type-IV secretion system protein TraC; Region: TraC-F-type; TIGR02746
1105111002449	Sex factor F TraW protein N terminal; Region: TraW_N; cl10149
1105111002450	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1105111002451	potential frameshift: common BLAST hit: gi|157827416|ref|YP_001496480.1| conjugal transfer protein TraU
1105111002452	Type-F conjugative transfer system pilin assembly protein; Region: TrbC_Ftype; pfam09673
1105111002453	potential frameshift: common BLAST hit: gi|157827418|ref|YP_001496482.1| conjugative transfer protein TraN
1105111002454	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
1105111002455	F plasmid transfer operon protein; Region: TraF; pfam13728
1105111002456	potential frameshift: common BLAST hit: gi|157827423|ref|YP_001496487.1| conjugative transfer protein TraD
1105111002457	Conjugal transfer protein TraD; Region: TraD; cl05753
1105111002458	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
1105111002459	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1105111002460	active site
1105111002461	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1105111002462	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
1105111002463	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1105111002464	Leucine rich repeat, ribonuclease inhibitor type; Region: LRR_RI; smart00368
1105111002465	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1105111002466	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1105111002467	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1105111002468	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1105111002469	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1105111002470	oligomer interface [polypeptide binding]; other site
1105111002471	active site residues [active]
1105111002472	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1105111002473	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1105111002474	RNA binding site [nucleotide binding]; other site
1105111002475	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1105111002476	RNA binding site [nucleotide binding]; other site
1105111002477	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1105111002478	RNA binding site [nucleotide binding]; other site
1105111002479	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105111002480	RNA binding site [nucleotide binding]; other site
1105111002481	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105111002482	RNA binding site [nucleotide binding]; other site
1105111002483	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105111002484	RNA binding site [nucleotide binding]; other site
1105111002485	Cytidylate kinase [Nucleotide transport and metabolism]; Region: Cmk; COG0283
1105111002486	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1105111002487	CMP-binding site; other site
1105111002488	The sites determining sugar specificity; other site
1105111002489	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105111002490	sequence-specific DNA binding site [nucleotide binding]; other site
1105111002491	salt bridge; other site
1105111002492	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1105111002493	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1105111002494	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1105111002495	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105111002496	ATP binding site [chemical binding]; other site
1105111002497	Mg2+ binding site [ion binding]; other site
1105111002498	G-X-G motif; other site
1105111002499	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111002500	HD domain; Region: HD_4; pfam13328
1105111002501	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111002502	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1105111002503	synthetase active site [active]
1105111002504	NTP binding site [chemical binding]; other site
1105111002505	metal binding site [ion binding]; metal-binding site
1105111002506	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1105111002507	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105111002508	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105111002509	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105111002510	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105111002511	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111002512	HD domain; Region: HD_4; pfam13328
1105111002513	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
1105111002514	BNR repeat-like domain; Region: BNR_2; pfam13088
1105111002515	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111002516	putative substrate translocation pore; other site
1105111002517	Conjugal transfer protein TraD; Region: TraD; pfam06412
1105111002518	Ti-type conjugative transfer relaxase TraA; Region: TraA_Ti; TIGR02768
1105111002519	MobA/MobL family; Region: MobA_MobL; pfam03389
1105111002520	AAA domain; Region: AAA_30; pfam13604
1105111002521	Family description; Region: UvrD_C_2; pfam13538
1105111002522	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1105111002523	active site
1105111002524	metal binding site [ion binding]; metal-binding site
1105111002525	interdomain interaction site; other site
1105111002526	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105111002527	hypothetical protein; Provisional; Region: PRK09956
1105111002528	F sex factor protein N terminal; Region: TraD_N; pfam12615
1105111002529	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1105111002530	Type IV secretion-system coupling protein DNA-binding domain; Region: TrwB_AAD_bind; pfam10412
1105111002531	Walker A motif; other site
1105111002532	ATP binding site [chemical binding]; other site
1105111002533	Walker B motif; other site
1105111002534	TPR repeat; Region: TPR_11; pfam13414
1105111002535	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111002536	binding surface
1105111002537	TPR motif; other site
1105111002538	TPR repeat; Region: TPR_11; pfam13414
1105111002539	TPR repeat; Region: TPR_11; pfam13414
1105111002540	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111002541	binding surface
1105111002542	TPR motif; other site
1105111002543	TPR repeat; Region: TPR_11; pfam13414
1105111002544	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111002545	binding surface
1105111002546	TPR motif; other site
1105111002547	TPR repeat; Region: TPR_11; pfam13414
1105111002548	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111002549	TPR motif; other site
1105111002550	binding surface
1105111002551	TPR repeat; Region: TPR_11; pfam13414
1105111002552	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
1105111002553	Conjugative relaxosome accessory transposon protein; Region: TraH; pfam06122
1105111002554	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
1105111002555	F plasmid transfer operon protein; Region: TraF; pfam13728
1105111002556	Type-1V conjugative transfer system mating pair stabilisation; Region: TraN; pfam06986
1105111002557	HD domain; Region: HD_4; pfam13328
1105111002558	Winged helix-turn helix; Region: HTH_29; pfam13551
1105111002559	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1105111002560	Winged helix-turn helix; Region: HTH_33; pfam13592
1105111002561	DDE superfamily endonuclease; Region: DDE_3; pfam13358
1105111002562	YtxC-like family; Region: YtxC; cl08500
1105111002563	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111002564	HD domain; Region: HD_4; pfam13328
1105111002565	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111002566	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105111002567	putative substrate translocation pore; other site
1105111002568	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1105111002569	Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]; Region: HemK; COG2890
1105111002570	S-adenosylmethionine binding site [chemical binding]; other site
1105111002571	MobA/MobL family; Region: MobA_MobL; pfam03389
1105111002572	Conjugal transfer protein TraD; Region: TraD; pfam06412
1105111002573	SecA DEAD-like domain; Region: SecA_DEAD; pfam07517
1105111002574	SecA preprotein cross-linking domain; Region: SecA_PP_bind; cl03078
1105111002575	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1105111002576	nucleotide binding region [chemical binding]; other site
1105111002577	ATP-binding site [chemical binding]; other site
1105111002578	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1105111002579	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1105111002580	Walker A motif; other site
1105111002581	potential frameshift: common BLAST hit: gi|225630616|ref|YP_002727407.1| transposase
1105111002582	Helix-turn-helix domain; Region: HTH_28; pfam13518
1105111002583	Winged helix-turn helix; Region: HTH_29; pfam13551
1105111002584	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1105111002585	Walker B motif; other site
1105111002586	potential frameshift: common BLAST hit: gi|189183023|ref|YP_001936808.1| transposase
1105111002587	Ti-type conjugative transfer relaxase TraA; Region: TraA_Ti; TIGR02768
1105111002588	MobA/MobL family; Region: MobA_MobL; pfam03389
1105111002589	AAA domain; Region: AAA_30; pfam13604
1105111002590	Family description; Region: UvrD_C_2; pfam13538
1105111002591	DNA primase, catalytic core; Region: dnaG; TIGR01391
1105111002592	Toprim domain; Region: Toprim_3; pfam13362
1105111002593	Conjugal transfer protein TraD; Region: TraD; pfam06412
1105111002594	Toprim domain; Region: Toprim_3; pfam13362
1105111002595	active site
1105111002596	metal binding site [ion binding]; metal-binding site
1105111002597	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1105111002598	potential frameshift: common BLAST hit: gi|157964587|ref|YP_001499411.1| Phage-associated protein
1105111002599	potential frameshift: common BLAST hit: gi|157827433|ref|YP_001496497.1| site-specific DNA adenine methylase
1105111002600	RecG-like helicase [DNA replication, recombination, and repair / Transcription]; Region: RecG; COG1200
1105111002601	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1105111002602	ssDNA binding site; other site
1105111002603	generic binding surface II; other site
1105111002604	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105111002605	ATP binding site [chemical binding]; other site
1105111002606	putative Mg++ binding site [ion binding]; other site
1105111002607	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105111002608	nucleotide binding region [chemical binding]; other site
1105111002609	ATP-binding site [chemical binding]; other site
1105111002610	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1105111002611	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1105111002612	V-type ATP synthase subunit I; Validated; Region: PRK05771
1105111002613	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1105111002614	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1105111002615	Mg++ binding site [ion binding]; other site
1105111002616	putative catalytic motif [active]
1105111002617	putative substrate binding site [chemical binding]; other site
1105111002618	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1105111002619	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
1105111002620	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105111002621	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105111002622	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1105111002623	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1105111002624	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105111002625	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105111002626	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1105111002627	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1105111002628	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105111002629	ATP binding site [chemical binding]; other site
1105111002630	putative Mg++ binding site [ion binding]; other site
1105111002631	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105111002632	nucleotide binding region [chemical binding]; other site
1105111002633	ATP-binding site [chemical binding]; other site
1105111002634	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1105111002635	Uncharacterized conserved protein [Function unknown]; Region: COG2938
1105111002636	Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins; Region: RHOD_1; cd01522
1105111002637	active site residue [active]
1105111002638	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1105111002639	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1105111002640	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111002641	Walker A motif; other site
1105111002642	ATP binding site [chemical binding]; other site
1105111002643	Walker B motif; other site
1105111002644	arginine finger; other site
1105111002645	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1105111002646	DnaA box-binding interface [nucleotide binding]; other site
1105111002647	Patatin [General function prediction only]; Region: COG3621
1105111002648	Patatin-like phospholipase; includes PNPLA8, PNPLA9, and Pat17; Region: Pat17_PNPLA8_PNPLA9_like; cd07199
1105111002649	active site
1105111002650	nucleophile elbow; other site
1105111002651	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1105111002652	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111002653	putative substrate translocation pore; other site
1105111002654	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
1105111002655	GTP-binding protein YchF; Reviewed; Region: PRK09601
1105111002656	YchF GTPase; Region: YchF; cd01900
1105111002657	G1 box; other site
1105111002658	GTP/Mg2+ binding site [chemical binding]; other site
1105111002659	Switch I region; other site
1105111002660	G2 box; other site
1105111002661	Switch II region; other site
1105111002662	G3 box; other site
1105111002663	G4 box; other site
1105111002664	G5 box; other site
1105111002665	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1105111002666	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1105111002667	putative active site [active]
1105111002668	catalytic residue [active]
1105111002669	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1105111002670	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1105111002671	5S rRNA interface [nucleotide binding]; other site
1105111002672	CTC domain interface [polypeptide binding]; other site
1105111002673	L16 interface [polypeptide binding]; other site
1105111002674	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1105111002675	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105111002676	FeS/SAM binding site; other site
1105111002677	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1105111002678	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1105111002679	23S rRNA binding site [nucleotide binding]; other site
1105111002680	L21 binding site [polypeptide binding]; other site
1105111002681	L13 binding site [polypeptide binding]; other site
1105111002682	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1105111002683	ribonuclease P; Reviewed; Region: rnpA; PRK01492
1105111002684	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105111002685	potential frameshift: common BLAST hit: gi|157964755|ref|YP_001499579.1| magnesium/cobalt transporter CorA
1105111002686	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1105111002687	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms]; Region: NtrY; COG5000
1105111002688	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1105111002689	dimerization interface [polypeptide binding]; other site
1105111002690	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105111002691	dimer interface [polypeptide binding]; other site
1105111002692	phosphorylation site [posttranslational modification]
1105111002693	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105111002694	ATP binding site [chemical binding]; other site
1105111002695	Mg2+ binding site [ion binding]; other site
1105111002696	G-X-G motif; other site
1105111002697	Ribosomal protein S21 [Translation, ribosomal structure and biogenesis]; Region: RpsU; COG0828
1105111002698	Uncharacterized conserved protein [Function unknown]; Region: COG5590
1105111002699	COQ9; Region: COQ9; pfam08511
1105111002700	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
1105111002701	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1105111002702	HIGH motif; other site
1105111002703	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1105111002704	active site
1105111002705	KMSKS motif; other site
1105111002706	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
1105111002707	tRNA binding surface [nucleotide binding]; other site
1105111002708	anticodon binding site; other site
1105111002709	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105111002710	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1105111002711	TPR repeat; Region: TPR_11; pfam13414
1105111002712	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1105111002713	TPR motif; other site
1105111002714	binding surface
1105111002715	Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770
1105111002716	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1105111002717	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1105111002718	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1105111002719	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1105111002720	carboxyltransferase (CT) interaction site; other site
1105111002721	biotinylation site [posttranslational modification]; other site
1105111002722	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
1105111002723	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1105111002724	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1105111002725	acylglycerophosphoethanolamine acyltransferase; Provisional; Region: PRK06814
1105111002726	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111002727	putative substrate translocation pore; other site
1105111002728	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1105111002729	putative acyl-acceptor binding pocket; other site
1105111002730	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1105111002731	acyl-activating enzyme (AAE) consensus motif; other site
1105111002732	putative AMP binding site [chemical binding]; other site
1105111002733	TfoX N-terminal domain; Region: TfoX_N; pfam04993
1105111002734	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1105111002735	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
1105111002736	ABC-ATPase subunit  interface; other site
1105111002737	dimer interface [polypeptide binding]; other site
1105111002738	putative PBP binding regions; other site
1105111002739	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1105111002740	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111002741	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105111002742	S-adenosylmethionine binding site [chemical binding]; other site
1105111002743	glutamyl-tRNA synthetase; Provisional; Region: gltX; PRK14895
1105111002744	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1105111002745	HIGH motif; other site
1105111002746	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1105111002747	active site
1105111002748	KMSKS motif; other site
1105111002749	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111002750	Invasion protein B, involved in pathogenesis [General function prediction only]; Region: COG5342
1105111002751	Chitin binding domain; Region: Chitin_bind_3; cl03871
1105111002752	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111002753	HD domain; Region: HD_4; pfam13328
1105111002754	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111002755	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1105111002756	synthetase active site [active]
1105111002757	NTP binding site [chemical binding]; other site
1105111002758	metal binding site [ion binding]; metal-binding site
1105111002759	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1105111002760	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1105111002761	ring oligomerisation interface [polypeptide binding]; other site
1105111002762	ATP/Mg binding site [chemical binding]; other site
1105111002763	stacking interactions; other site
1105111002764	hinge regions; other site
1105111002765	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1105111002766	oligomerisation interface [polypeptide binding]; other site
1105111002767	mobile loop; other site
1105111002768	roof hairpin; other site
1105111002769	potential frameshift: common BLAST hit: gi|67458799|ref|YP_246423.1| glycosyltransferase
1105111002770	potential frameshift: common BLAST hit: gi|67458799|ref|YP_246423.1| glycosyltransferase
1105111002771	ribonuclease PH; Reviewed; Region: rph; PRK00173
1105111002772	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1105111002773	hexamer interface [polypeptide binding]; other site
1105111002774	active site
1105111002775	GrpE; Region: GrpE; pfam01025
1105111002776	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1105111002777	dimer interface [polypeptide binding]; other site
1105111002778	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1105111002779	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1105111002780	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1105111002781	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1105111002782	hypothetical protein; Validated; Region: PRK06620
1105111002783	potential frameshift: common BLAST hit: gi|67458578|ref|YP_246202.1| proline/betaine transporter
1105111002784	potential frameshift: common BLAST hit: gi|157826979|ref|YP_001496043.1| guanosine polyphosphate pyrophosphohydrolase/synthetase
1105111002785	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111002786	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111002787	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1105111002788	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
1105111002789	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1105111002790	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1105111002791	alphaNTD - beta interaction site [polypeptide binding]; other site
1105111002792	alphaNTD homodimer interface [polypeptide binding]; other site
1105111002793	alphaNTD - beta' interaction site [polypeptide binding]; other site
1105111002794	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1105111002795	30S ribosomal protein S11; Validated; Region: PRK05309
1105111002796	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
1105111002797	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1105111002798	adenylate kinase; Reviewed; Region: adk; PRK00279
1105111002799	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1105111002800	AMP-binding site [chemical binding]; other site
1105111002801	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1105111002802	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1105111002803	SecY translocase; Region: SecY; pfam00344
1105111002804	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1105111002805	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1105111002806	23S rRNA binding site [nucleotide binding]; other site
1105111002807	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1105111002808	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1105111002809	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1105111002810	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1105111002811	5S rRNA interface [nucleotide binding]; other site
1105111002812	23S rRNA interface [nucleotide binding]; other site
1105111002813	L5 interface [polypeptide binding]; other site
1105111002814	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1105111002815	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1105111002816	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1105111002817	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1105111002818	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1105111002819	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1105111002820	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1105111002821	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1105111002822	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1105111002823	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1105111002824	RNA binding site [nucleotide binding]; other site
1105111002825	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1105111002826	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1105111002827	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1105111002828	L23 interface [polypeptide binding]; other site
1105111002829	trigger factor interaction site; other site
1105111002830	23S rRNA interface [nucleotide binding]; other site
1105111002831	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1105111002832	23S rRNA interface [nucleotide binding]; other site
1105111002833	5S rRNA interface [nucleotide binding]; other site
1105111002834	putative antibiotic binding site [chemical binding]; other site
1105111002835	L25 interface [polypeptide binding]; other site
1105111002836	L27 interface [polypeptide binding]; other site
1105111002837	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1105111002838	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1105111002839	G-X-X-G motif; other site
1105111002840	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1105111002841	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1105111002842	putative translocon binding site; other site
1105111002843	protein-rRNA interface [nucleotide binding]; other site
1105111002844	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1105111002845	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1105111002846	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1105111002847	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1105111002848	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1105111002849	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1105111002850	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1105111002851	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1105111002852	elongation factor Tu; Reviewed; Region: PRK00049
1105111002853	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1105111002854	G1 box; other site
1105111002855	GEF interaction site [polypeptide binding]; other site
1105111002856	GTP/Mg2+ binding site [chemical binding]; other site
1105111002857	Switch I region; other site
1105111002858	G2 box; other site
1105111002859	G3 box; other site
1105111002860	Switch II region; other site
1105111002861	G4 box; other site
1105111002862	G5 box; other site
1105111002863	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1105111002864	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1105111002865	Antibiotic Binding Site [chemical binding]; other site
1105111002866	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1105111002867	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1105111002868	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1105111002869	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1105111002870	Class II fumarases; Region: Fumarase_classII; cd01362
1105111002871	active site
1105111002872	tetramer interface [polypeptide binding]; other site
1105111002873	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
1105111002874	homotetrameric interface [polypeptide binding]; other site
1105111002875	putative active site [active]
1105111002876	metal binding site [ion binding]; metal-binding site
1105111002877	cell division protein FtsZ; Validated; Region: PRK09330
1105111002878	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1105111002879	nucleotide binding site [chemical binding]; other site
1105111002880	SulA interaction site; other site
1105111002881	potential frameshift: common BLAST hit: gi|341584204|ref|YP_004764695.1| ecotin
1105111002882	potential frameshift: common BLAST hit: gi|67458660|ref|YP_246284.1| ecotin
1105111002883	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; smart00932
1105111002884	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1105111002885	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1105111002886	muropeptide transporter; Validated; Region: ampG; cl17669
1105111002887	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1105111002888	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1105111002889	ATP binding site [chemical binding]; other site
1105111002890	Mg++ binding site [ion binding]; other site
1105111002891	motif III; other site
1105111002892	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105111002893	nucleotide binding region [chemical binding]; other site
1105111002894	ATP-binding site [chemical binding]; other site
1105111002895	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1105111002896	DNA-binding site [nucleotide binding]; DNA binding site
1105111002897	RNA-binding motif; other site
1105111002898	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1105111002899	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105111002900	S-adenosylmethionine binding site [chemical binding]; other site
1105111002901	SurA N-terminal domain; Region: SurA_N_3; cl07813
1105111002902	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1105111002903	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1105111002904	Exonuclease VII, large subunit [DNA replication, recombination, and repair]; Region: XseA; COG1570
1105111002905	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1105111002906	generic binding surface II; other site
1105111002907	generic binding surface I; other site
1105111002908	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1105111002909	putative catalytic site [active]
1105111002910	putative phosphate binding site [ion binding]; other site
1105111002911	active site
1105111002912	metal binding site A [ion binding]; metal-binding site
1105111002913	DNA binding site [nucleotide binding]
1105111002914	putative AP binding site [nucleotide binding]; other site
1105111002915	putative metal binding site B [ion binding]; other site
1105111002916	Uncharacterized conserved protein [Function unknown]; Region: COG4095
1105111002917	GTP-binding protein Der; Reviewed; Region: PRK00093
1105111002918	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1105111002919	G1 box; other site
1105111002920	GTP/Mg2+ binding site [chemical binding]; other site
1105111002921	Switch I region; other site
1105111002922	G2 box; other site
1105111002923	Switch II region; other site
1105111002924	G3 box; other site
1105111002925	G4 box; other site
1105111002926	G5 box; other site
1105111002927	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1105111002928	G1 box; other site
1105111002929	GTP/Mg2+ binding site [chemical binding]; other site
1105111002930	Switch I region; other site
1105111002931	G2 box; other site
1105111002932	G3 box; other site
1105111002933	Switch II region; other site
1105111002934	G4 box; other site
1105111002935	G5 box; other site
1105111002936	potential frameshift: common BLAST hit: gi|374319630|ref|YP_005066129.1| Putative AAA+ superfamily ATPase
1105111002937	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1105111002938	ABC1 family; Region: ABC1; pfam03109
1105111002939	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1105111002940	active site
1105111002941	ATP binding site [chemical binding]; other site
1105111002942	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1105111002943	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105111002944	S-adenosylmethionine binding site [chemical binding]; other site
1105111002945	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1105111002946	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1105111002947	DNA binding site [nucleotide binding]
1105111002948	catalytic residue [active]
1105111002949	H2TH interface [polypeptide binding]; other site
1105111002950	putative catalytic residues [active]
1105111002951	turnover-facilitating residue; other site
1105111002952	intercalation triad [nucleotide binding]; other site
1105111002953	8OG recognition residue [nucleotide binding]; other site
1105111002954	putative reading head residues; other site
1105111002955	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1105111002956	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1105111002957	potential frameshift: common BLAST hit: gi|15892962|ref|NP_360676.1| mannose-1-phosphate guanylyltransferase
1105111002958	potential frameshift: common BLAST hit: gi|67458633|ref|YP_246257.1| mannose-1-phosphate guanylyltransferase
1105111002959	potential frameshift: common BLAST hit: gi|67458630|ref|YP_246254.1| Poly-beta-hydroxyalkanoate depolymerase
1105111002960	Protein of unknown function (DUF511); Region: DUF511; cl01114
1105111002961	Protein of unknown function (DUF511); Region: DUF511; cl01114
1105111002962	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1105111002963	active site
1105111002964	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
1105111002965	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1105111002966	HIGH motif; other site
1105111002967	active site
1105111002968	KMSKS motif; other site
1105111002969	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1105111002970	tRNA binding surface [nucleotide binding]; other site
1105111002971	anticodon binding site; other site
1105111002972	thymidylate kinase; Validated; Region: tmk; PRK00698
1105111002973	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1105111002974	TMP-binding site; other site
1105111002975	ATP-binding site [chemical binding]; other site
1105111002976	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105111002977	4-hydroxybenzoate polyprenyltransferase; Reviewed; Region: ubiA; PRK12847
1105111002978	UbiA prenyltransferase family; Region: UbiA; pfam01040
1105111002979	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1105111002980	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105111002981	valyl-tRNA synthetase; Reviewed; Region: valS; PRK13208
1105111002982	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105111002983	active site
1105111002984	HIGH motif; other site
1105111002985	nucleotide binding site [chemical binding]; other site
1105111002986	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1105111002987	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105111002988	active site
1105111002989	KMSKS motif; other site
1105111002990	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1105111002991	tRNA binding surface [nucleotide binding]; other site
1105111002992	anticodon binding site; other site
1105111002993	LPS biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3475
1105111002994	LPS biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3475
1105111002995	AAA domain; Region: AAA_14; pfam13173
1105111002996	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1105111002997	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
1105111002998	RmuC family; Region: RmuC; pfam02646
1105111002999	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1105111003000	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1105111003001	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1105111003002	NAD(P) binding site [chemical binding]; other site
1105111003003	potential frameshift: common BLAST hit: gi|67458613|ref|YP_246237.1| oxidoreductase protein
1105111003004	Predicted integral membrane protein (DUF2269); Region: DUF2269; pfam10027
1105111003005	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1105111003006	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1105111003007	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105111003008	Walker A motif; other site
1105111003009	ATP binding site [chemical binding]; other site
1105111003010	Walker B motif; other site
1105111003011	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1105111003012	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1105111003013	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1105111003014	Coenzyme A binding pocket [chemical binding]; other site
1105111003015	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1105111003016	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
1105111003017	HicB family; Region: HicB; pfam05534
1105111003018	YcfA-like protein; Region: YcfA; cl00752
1105111003019	ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204
1105111003020	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105111003021	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105111003022	Walker A/P-loop; other site
1105111003023	ATP binding site [chemical binding]; other site
1105111003024	Q-loop/lid; other site
1105111003025	ABC transporter signature motif; other site
1105111003026	Walker B; other site
1105111003027	D-loop; other site
1105111003028	H-loop/switch region; other site
1105111003029	Protein of unknown function (DUF2673); Region: DUF2673; pfam10880
1105111003030	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111003031	putative substrate translocation pore; other site
1105111003032	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
1105111003033	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1105111003034	FtsX-like permease family; Region: FtsX; pfam02687
1105111003035	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1105111003036	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1105111003037	Walker A/P-loop; other site
1105111003038	ATP binding site [chemical binding]; other site
1105111003039	Q-loop/lid; other site
1105111003040	ABC transporter signature motif; other site
1105111003041	Walker B; other site
1105111003042	D-loop; other site
1105111003043	H-loop/switch region; other site
1105111003044	Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism]; Region: CorB; COG4536
1105111003045	Domain of unknown function DUF21; Region: DUF21; pfam01595
1105111003046	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1105111003047	Transporter associated domain; Region: CorC_HlyC; smart01091
1105111003048	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
1105111003049	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111003050	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111003051	Rickettsia outer membrane protein B; Region: rOmpB; pfam12334
1105111003052	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1105111003053	Autotransporter beta-domain; Region: Autotransporter; smart00869
1105111003054	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111003055	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1105111003056	synthetase active site [active]
1105111003057	NTP binding site [chemical binding]; other site
1105111003058	metal binding site [ion binding]; metal-binding site
1105111003059	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1105111003060	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
1105111003061	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1105111003062	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1105111003063	DNA binding residues [nucleotide binding]
1105111003064	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1105111003065	IHF dimer interface [polypeptide binding]; other site
1105111003066	IHF - DNA interface [nucleotide binding]; other site
1105111003067	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1105111003068	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1105111003069	catalytic triad [active]
1105111003070	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1105111003071	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1105111003072	putative acyl-acceptor binding pocket; other site
1105111003073	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1105111003074	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1105111003075	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1105111003076	Peptidase family M23; Region: Peptidase_M23; pfam01551
1105111003077	Protein of unknown function (DUF519); Region: DUF519; pfam04378
1105111003078	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1105111003079	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1105111003080	nucleotide binding pocket [chemical binding]; other site
1105111003081	K-X-D-G motif; other site
1105111003082	catalytic site [active]
1105111003083	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1105111003084	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1105111003085	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1105111003086	Dimer interface [polypeptide binding]; other site
1105111003087	BRCT sequence motif; other site
1105111003088	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1105111003089	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1105111003090	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111003091	HD domain; Region: HD_4; pfam13328
1105111003092	potential frameshift: common BLAST hit: gi|91205620|ref|YP_537975.1| proline/betaine transporter
1105111003093	potential frameshift: common BLAST hit: gi|67458578|ref|YP_246202.1| proline/betaine transporter
1105111003094	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1105111003095	mce related protein; Region: MCE; pfam02470
1105111003096	hypothetical protein; Provisional; Region: PRK06630
1105111003097	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1105111003098	RNA/DNA hybrid binding site [nucleotide binding]; other site
1105111003099	active site
1105111003100	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3814
1105111003101	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3494
1105111003102	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1105111003103	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1105111003104	CoA-binding site [chemical binding]; other site
1105111003105	ATP-binding [chemical binding]; other site
1105111003106	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1105111003107	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1105111003108	active site
1105111003109	catalytic site [active]
1105111003110	substrate binding site [chemical binding]; other site
1105111003111	SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662
1105111003112	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
1105111003113	Part of AAA domain; Region: AAA_19; pfam13245
1105111003114	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
1105111003115	UvrD-like helicase C-terminal domain; Region: UvrD_C; pfam13361
1105111003116	Family description; Region: UvrD_C_2; pfam13538
1105111003117	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1105111003118	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1105111003119	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111003120	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111003121	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1105111003122	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105111003123	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
1105111003124	AAA domain; Region: AAA_12; pfam13087
1105111003125	acetyl-CoA acetyltransferase; Provisional; Region: PRK06633
1105111003126	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1105111003127	dimer interface [polypeptide binding]; other site
1105111003128	active site
1105111003129	potential frameshift: common BLAST hit: gi|157964877|ref|YP_001499701.1| Poly-beta-hydroxybutyrate polymerase
1105111003130	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105111003131	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a...; Region: Nudix_Hydrolase_1; cd03674
1105111003132	nudix motif; other site
1105111003133	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1105111003134	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1105111003135	Transporter associated domain; Region: CorC_HlyC; smart01091
1105111003136	metal-binding heat shock protein; Provisional; Region: PRK00016
1105111003137	PemK-like protein; Region: PemK; cl00995
1105111003138	lipoyl synthase; Provisional; Region: PRK05481
1105111003139	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105111003140	FeS/SAM binding site; other site
1105111003141	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1105111003142	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1105111003143	dimer interface [polypeptide binding]; other site
1105111003144	active site
1105111003145	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1105111003146	folate binding site [chemical binding]; other site
1105111003147	Predicted esterase [General function prediction only]; Region: COG0400
1105111003148	putative hydrolase; Provisional; Region: PRK11460
1105111003149	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1105111003150	putative GSH binding site [chemical binding]; other site
1105111003151	catalytic residues [active]
1105111003152	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1105111003153	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1105111003154	minor groove reading motif; other site
1105111003155	helix-hairpin-helix signature motif; other site
1105111003156	substrate binding pocket [chemical binding]; other site
1105111003157	active site
1105111003158	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1105111003159	Entericidin EcnA/B family; Region: Entericidin; cl02322
1105111003160	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105111003161	Predicted methyltransferases [General function prediction only]; Region: COG0313
1105111003162	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1105111003163	putative SAM binding site [chemical binding]; other site
1105111003164	putative homodimer interface [polypeptide binding]; other site
1105111003165	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1105111003166	putative ligand binding site [chemical binding]; other site
1105111003167	twin arginine translocase protein A; Provisional; Region: tatA; PRK01470
1105111003168	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1105111003169	tetramer interfaces [polypeptide binding]; other site
1105111003170	binuclear metal-binding site [ion binding]; other site
1105111003171	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1105111003172	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1105111003173	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1105111003174	aspartate kinase; Reviewed; Region: PRK06635
1105111003175	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1105111003176	putative nucleotide binding site [chemical binding]; other site
1105111003177	putative catalytic residues [active]
1105111003178	putative Mg ion binding site [ion binding]; other site
1105111003179	putative aspartate binding site [chemical binding]; other site
1105111003180	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
1105111003181	putative allosteric regulatory residue; other site
1105111003182	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1105111003183	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105111003184	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1105111003185	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1105111003186	potential frameshift: common BLAST hit: gi|157964899|ref|YP_001499723.1| beta-lactamase
1105111003187	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105111003188	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105111003189	putative substrate translocation pore; other site
1105111003190	Cell division protein ZapA (stimulator of FtsZ polymerization and Z-ring component) [Cell cycle control, cell division,    chromosome partitioning]; Region: zapA; COG3027
1105111003191	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111003192	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
1105111003193	Helix-turn-helix domain; Region: HTH_25; pfam13413
1105111003194	NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism]; Region: COG2902
1105111003195	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; smart00839
1105111003196	Predicted GTPase [General function prediction only]; Region: ThdF; COG0486
1105111003197	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1105111003198	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1105111003199	G1 box; other site
1105111003200	GTP/Mg2+ binding site [chemical binding]; other site
1105111003201	Switch I region; other site
1105111003202	G2 box; other site
1105111003203	Switch II region; other site
1105111003204	G3 box; other site
1105111003205	G4 box; other site
1105111003206	G5 box; other site
1105111003207	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1105111003208	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1105111003209	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1105111003210	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
1105111003211	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1105111003212	RecA/RadA recombinase [DNA replication, recombination, and repair]; Region: RecA; COG0468
1105111003213	hexamer interface [polypeptide binding]; other site
1105111003214	Walker A motif; other site
1105111003215	ATP binding site [chemical binding]; other site
1105111003216	Walker B motif; other site
1105111003217	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1105111003218	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1105111003219	NAD(P) binding site [chemical binding]; other site
1105111003220	active site
1105111003221	acyl carrier protein; Provisional; Region: acpP; PRK00982
1105111003222	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1105111003223	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1105111003224	dimer interface [polypeptide binding]; other site
1105111003225	active site
1105111003226	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1105111003227	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105111003228	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105111003229	endonuclease subunit; Provisional; Region: 46; PHA02562
1105111003230	AAA domain; Region: AAA_14; pfam13173
1105111003231	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1105111003232	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111003233	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1105111003234	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1105111003235	catalytic site [active]
1105111003236	G-X2-G-X-G-K; other site
1105111003237	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105111003238	sequence-specific DNA binding site [nucleotide binding]; other site
1105111003239	salt bridge; other site
1105111003240	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
1105111003241	rod shape-determining protein MreC; Region: MreC; pfam04085
1105111003242	rod shape-determining protein MreB; Provisional; Region: PRK13927
1105111003243	MreB and similar proteins; Region: MreB_like; cd10225
1105111003244	nucleotide binding site [chemical binding]; other site
1105111003245	Mg binding site [ion binding]; other site
1105111003246	putative protofilament interaction site [polypeptide binding]; other site
1105111003247	RodZ interaction site [polypeptide binding]; other site
1105111003248	Predicted permeases [General function prediction only]; Region: COG0795
1105111003249	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1105111003250	putative outer membrane lipoprotein; Provisional; Region: PRK09967
1105111003251	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1105111003252	ligand binding site [chemical binding]; other site
1105111003253	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1105111003254	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1105111003255	dimer interface [polypeptide binding]; other site
1105111003256	active site
1105111003257	CoA binding pocket [chemical binding]; other site
1105111003258	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
1105111003259	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
1105111003260	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1105111003261	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1105111003262	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1105111003263	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1105111003264	P loop; other site
1105111003265	GTP binding site [chemical binding]; other site
1105111003266	DNA polymerase I; Provisional; Region: PRK05755
1105111003267	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1105111003268	active site
1105111003269	metal binding site 1 [ion binding]; metal-binding site
1105111003270	putative 5' ssDNA interaction site; other site
1105111003271	metal binding site 3; metal-binding site
1105111003272	metal binding site 2 [ion binding]; metal-binding site
1105111003273	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1105111003274	putative DNA binding site [nucleotide binding]; other site
1105111003275	putative metal binding site [ion binding]; other site
1105111003276	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1105111003277	active site
1105111003278	substrate binding site [chemical binding]; other site
1105111003279	catalytic site [active]
1105111003280	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1105111003281	active site
1105111003282	DNA binding site [nucleotide binding]
1105111003283	catalytic site [active]
1105111003284	potential frameshift: common BLAST hit: gi|157826229|ref|YP_001493949.1| S-adenosylmethionine synthetase
1105111003285	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1105111003286	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111003287	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105111003288	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1105111003289	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1105111003290	putative active site [active]
1105111003291	putative PHP Thumb interface [polypeptide binding]; other site
1105111003292	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1105111003293	generic binding surface I; other site
1105111003294	generic binding surface II; other site
1105111003295	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1105111003296	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1105111003297	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1105111003298	Protein of unknown function; Region: DUF3971; pfam13116
1105111003299	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1105111003300	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1105111003301	muropeptide transporter; Validated; Region: ampG; cl17669
1105111003302	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1105111003303	seryl-tRNA synthetase; Provisional; Region: PRK05431
1105111003304	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1105111003305	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1105111003306	dimer interface [polypeptide binding]; other site
1105111003307	active site
1105111003308	motif 1; other site
1105111003309	motif 2; other site
1105111003310	motif 3; other site
1105111003311	Rickettsial palindromic element RPE5 domain; Region: RPE5; TIGR03776
1105111003312	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1105111003313	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1105111003314	Integral membrane protein TerC family; Region: TerC; cl10468
1105111003315	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1105111003316	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1105111003317	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105111003318	S-adenosylmethionine binding site [chemical binding]; other site
1105111003319	Predicted regulatory domain of a methyltransferase [General function prediction only]; Region: COG4797
1105111003320	potential frameshift: common BLAST hit: gi|165933781|ref|YP_001650570.1| transcriptional repressor
1105111003321	potential frameshift: common BLAST hit: gi|165933781|ref|YP_001650570.1| transcriptional repressor
1105111003322	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1105111003323	NADH dehydrogenase subunit 6; Provisional; Region: ND6; MTH00213
1105111003324	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1105111003325	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1105111003326	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105111003327	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1105111003328	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105111003329	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13541
1105111003330	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105111003331	Walker A/P-loop; other site
1105111003332	ATP binding site [chemical binding]; other site
1105111003333	Q-loop/lid; other site
1105111003334	ABC transporter signature motif; other site
1105111003335	Walker B; other site
1105111003336	D-loop; other site
1105111003337	H-loop/switch region; other site
1105111003338	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1105111003339	4Fe-4S binding domain; Region: Fer4; cl02805
1105111003340	4Fe-4S binding domain; Region: Fer4; pfam00037
1105111003341	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1105111003342	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1105111003343	NADH dehydrogenase subunit G; Validated; Region: PRK09130
1105111003344	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1105111003345	catalytic loop [active]
1105111003346	iron binding site [ion binding]; other site
1105111003347	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1105111003348	MopB_Res_Cmplx1_Nad11: The second domain of the Nad11/75-kDa subunit of the NADH-quinone oxidoreductase/respiratory complex I/NADH dehydrogenase-1(NDH-1) of eukaryotes and the Nqo3/G subunit of alphaproteobacteria NDH-1. The NADH-quinone oxidoreductase...; Region: MopB_Res-Cmplx1_Nad11; cd02773
1105111003349	Domain of unknown function (DUF1982); Region: DUF1982; pfam09326
1105111003350	Predicted membrane protein [Function unknown]; Region: COG3671
1105111003351	aconitate hydratase; Validated; Region: PRK09277
1105111003352	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1105111003353	substrate binding site [chemical binding]; other site
1105111003354	ligand binding site [chemical binding]; other site
1105111003355	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1105111003356	substrate binding site [chemical binding]; other site
1105111003357	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK01474
1105111003358	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1105111003359	gamma subunit interface [polypeptide binding]; other site
1105111003360	epsilon subunit interface [polypeptide binding]; other site
1105111003361	LBP interface [polypeptide binding]; other site
1105111003362	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1105111003363	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1105111003364	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1105111003365	alpha subunit interaction interface [polypeptide binding]; other site
1105111003366	Walker A motif; other site
1105111003367	ATP binding site [chemical binding]; other site
1105111003368	Walker B motif; other site
1105111003369	inhibitor binding site; inhibition site
1105111003370	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1105111003371	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1105111003372	core domain interface [polypeptide binding]; other site
1105111003373	delta subunit interface [polypeptide binding]; other site
1105111003374	epsilon subunit interface [polypeptide binding]; other site
1105111003375	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1105111003376	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1105111003377	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1105111003378	beta subunit interaction interface [polypeptide binding]; other site
1105111003379	Walker A motif; other site
1105111003380	ATP binding site [chemical binding]; other site
1105111003381	Walker B motif; other site
1105111003382	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1105111003383	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1105111003384	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1105111003385	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1105111003386	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1105111003387	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105111003388	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1105111003389	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1105111003390	dinuclear metal binding motif [ion binding]; other site
1105111003391	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1105111003392	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1105111003393	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
1105111003394	Transglycosylase; Region: Transgly; pfam00912
1105111003395	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1105111003396	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1105111003397	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1105111003398	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105111003399	FeS/SAM binding site; other site
1105111003400	TRAM domain; Region: TRAM; pfam01938
1105111003401	potential frameshift: common BLAST hit: gi|67459672|ref|YP_247296.1| nucleotidyltransferase/HEPN domain-containing protein
1105111003402	potential frameshift: common BLAST hit: gi|67459672|ref|YP_247296.1| nucleotidyltransferase/HEPN domain-containing protein
1105111003403	potential frameshift: common BLAST hit: gi|67459332|ref|YP_246956.1| nucleotidyltransferase/HEPN domain-containing protein
1105111003404	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105111003405	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3807
1105111003406	Bacterial SH3 domain; Region: SH3_4; pfam06347
1105111003407	Bacterial SH3 domain; Region: SH3_4; pfam06347
1105111003408	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1105111003409	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1105111003410	TrkA-N domain; Region: TrkA_N; pfam02254
1105111003411	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
1105111003412	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
1105111003413	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105111003414	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105111003415	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105111003416	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1105111003417	rRNA binding site [nucleotide binding]; other site
1105111003418	predicted 30S ribosome binding site; other site
1105111003419	Maf-like protein; Region: Maf; pfam02545
1105111003420	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1105111003421	active site
1105111003422	dimer interface [polypeptide binding]; other site
1105111003423	RNA polymerase-binding protein DksA; Region: dksA; TIGR02420
1105111003424	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1105111003425	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1105111003426	active site
1105111003427	DNA binding site [nucleotide binding]
1105111003428	Int/Topo IB signature motif; other site
1105111003429	Phasin protein; Region: Phasin_2; pfam09361
1105111003430	potential frameshift: common BLAST hit: gi|67459690|ref|YP_247314.1| Poly(3-hydroxyalkanoate) synthetase
1105111003431	potential frameshift: common BLAST hit: gi|67459690|ref|YP_247314.1| Poly(3-hydroxyalkanoate) synthetase
1105111003432	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1105111003433	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1105111003434	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1105111003435	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1105111003436	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1105111003437	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1105111003438	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1105111003439	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1105111003440	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1105111003441	potential frameshift: common BLAST hit: gi|374319799|ref|YP_005066298.1| Putative acyltransferase
1105111003442	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1105111003443	active site
1105111003444	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1105111003445	potential frameshift: common BLAST hit: gi|91204972|ref|YP_537327.1| DNA repair protein RadC
1105111003446	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1105111003447	The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854
1105111003448	Mg++ binding site [ion binding]; other site
1105111003449	putative catalytic motif [active]
1105111003450	putative substrate binding site [chemical binding]; other site
1105111003451	Protein of unknown function (DUF721); Region: DUF721; pfam05258
1105111003452	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1105111003453	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1105111003454	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1105111003455	catalytic residues [active]
1105111003456	catalytic nucleophile [active]
1105111003457	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1105111003458	Presynaptic Site I dimer interface [polypeptide binding]; other site
1105111003459	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1105111003460	Synaptic Flat tetramer interface [polypeptide binding]; other site
1105111003461	Synaptic Site I dimer interface [polypeptide binding]; other site
1105111003462	DNA binding site [nucleotide binding]
1105111003463	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1105111003464	DNA-binding interface [nucleotide binding]; DNA binding site
1105111003465	HD domain; Region: HD_4; pfam13328
1105111003466	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105111003467	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1105111003468	synthetase active site [active]
1105111003469	NTP binding site [chemical binding]; other site
1105111003470	metal binding site [ion binding]; metal-binding site
1105111003471	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1105111003472	Leucine-rich repeats; other site
1105111003473	Substrate binding site [chemical binding]; other site
1105111003474	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111003475	TPR repeat; Region: TPR_11; pfam13414
1105111003476	binding surface
1105111003477	TPR motif; other site
1105111003478	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105111003479	TPR motif; other site
1105111003480	HicB family; Region: HicB; pfam05534
1105111003481	ParA-like protein; Provisional; Region: PHA02518
1105111003482	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105111003483	P-loop; other site
1105111003484	Magnesium ion binding site [ion binding]; other site
1105111003485	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1105111003486	HTH-like domain; Region: HTH_21; pfam13276
1105111003487	Integrase core domain; Region: rve; pfam00665
1105111003488	putative transposase; Provisional; Region: PRK09857
1105111003489	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105111003490	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1105111003491	Integrase core domain; Region: rve; pfam00665