-- dump date   	20140619_024056
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
696127000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
696127000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
696127000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696127000004	Walker A motif; other site
696127000005	ATP binding site [chemical binding]; other site
696127000006	Walker B motif; other site
696127000007	arginine finger; other site
696127000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
696127000009	DnaA box-binding interface [nucleotide binding]; other site
696127000010	Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139
696127000011	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK12782
696127000012	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
696127000013	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
696127000014	Flagellar basal body protein [Cell motility and secretion]; Region: FlgB; COG1815
696127000015	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
696127000016	active site
696127000017	intersubunit interactions; other site
696127000018	catalytic residue [active]
696127000019	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
696127000020	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
696127000021	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
696127000022	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
696127000023	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
696127000024	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
696127000025	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
696127000026	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
696127000027	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
696127000028	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
696127000029	substrate binding pocket [chemical binding]; other site
696127000030	chain length determination region; other site
696127000031	substrate-Mg2+ binding site; other site
696127000032	catalytic residues [active]
696127000033	aspartate-rich region 1; other site
696127000034	active site lid residues [active]
696127000035	aspartate-rich region 2; other site
696127000036	Uncharacterized ACR, YagE family COG1723; Region: DUF155; cl00751
696127000037	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
696127000038	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
696127000039	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
696127000040	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
696127000041	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
696127000042	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
696127000043	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696127000044	Walker A motif; other site
696127000045	ATP binding site [chemical binding]; other site
696127000046	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
696127000047	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
696127000048	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
696127000049	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
696127000050	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000051	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
696127000052	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
696127000053	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
696127000054	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
696127000055	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
696127000056	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
696127000057	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
696127000058	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
696127000059	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
696127000060	putative translocon binding site; other site
696127000061	protein-rRNA interface [nucleotide binding]; other site
696127000062	ribosomal protein S3, bacterial type; Region: rpsC_bact; TIGR01009
696127000063	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
696127000064	G-X-X-G motif; other site
696127000065	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
696127000066	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
696127000067	23S rRNA interface [nucleotide binding]; other site
696127000068	5S rRNA interface [nucleotide binding]; other site
696127000069	putative antibiotic binding site [chemical binding]; other site
696127000070	L25 interface [polypeptide binding]; other site
696127000071	L27 interface [polypeptide binding]; other site
696127000072	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
696127000073	23S rRNA interface [nucleotide binding]; other site
696127000074	putative translocon interaction site; other site
696127000075	signal recognition particle (SRP54) interaction site; other site
696127000076	L23 interface [polypeptide binding]; other site
696127000077	trigger factor interaction site; other site
696127000078	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
696127000079	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
696127000080	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
696127000081	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
696127000082	RNA binding site [nucleotide binding]; other site
696127000083	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
696127000084	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
696127000085	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
696127000086	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
696127000087	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
696127000088	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
696127000089	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
696127000090	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
696127000091	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
696127000092	23S rRNA interface [nucleotide binding]; other site
696127000093	L21e interface [polypeptide binding]; other site
696127000094	5S rRNA interface [nucleotide binding]; other site
696127000095	L27 interface [polypeptide binding]; other site
696127000096	L5 interface [polypeptide binding]; other site
696127000097	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
696127000098	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
696127000099	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
696127000100	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
696127000101	23S rRNA binding site [nucleotide binding]; other site
696127000102	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
696127000103	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
696127000104	SecY translocase; Region: SecY; pfam00344
696127000105	adenylate kinase; Reviewed; Region: adk; PRK00279
696127000106	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
696127000107	AMP-binding site [chemical binding]; other site
696127000108	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
696127000109	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
696127000110	30S ribosomal protein S13; Region: bact_S13; TIGR03631
696127000111	Ribosomal protein S11; Region: Ribosomal_S11; cl00332
696127000112	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
696127000113	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
696127000114	alphaNTD - beta interaction site [polypeptide binding]; other site
696127000115	alphaNTD homodimer interface [polypeptide binding]; other site
696127000116	alphaNTD - beta' interaction site [polypeptide binding]; other site
696127000117	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
696127000118	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
696127000119	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000120	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
696127000121	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
696127000122	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
696127000123	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
696127000124	tetramer interface [polypeptide binding]; other site
696127000125	TPP-binding site [chemical binding]; other site
696127000126	heterodimer interface [polypeptide binding]; other site
696127000127	phosphorylation loop region [posttranslational modification]
696127000128	pyruvate dehydrogenase subunit beta; Validated; Region: PRK09212
696127000129	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
696127000130	alpha subunit interface [polypeptide binding]; other site
696127000131	TPP binding site [chemical binding]; other site
696127000132	heterodimer interface [polypeptide binding]; other site
696127000133	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
696127000134	Family description; Region: VCBS; pfam13517
696127000135	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000136	Family description; Region: VCBS; pfam13517
696127000137	Family description; Region: VCBS; pfam13517
696127000138	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
696127000139	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696127000140	active site
696127000141	motif I; other site
696127000142	motif II; other site
696127000143	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
696127000144	Proline dehydrogenase; Region: Pro_dh; cl03282
696127000145	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
696127000146	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000147	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
696127000148	Peptidase family M48; Region: Peptidase_M48; cl12018
696127000149	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
696127000150	RuvA N terminal domain; Region: RuvA_N; pfam01330
696127000151	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
696127000152	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
696127000153	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
696127000154	dimer interface [polypeptide binding]; other site
696127000155	active site
696127000156	glycine-pyridoxal phosphate binding site [chemical binding]; other site
696127000157	folate binding site [chemical binding]; other site
696127000158	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
696127000159	FG-GAP repeat; Region: FG-GAP; cl15299
696127000160	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000161	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
696127000162	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
696127000163	E3 interaction surface; other site
696127000164	lipoyl attachment site [posttranslational modification]; other site
696127000165	e3 binding domain; Region: E3_binding; pfam02817
696127000166	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
696127000167	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
696127000168	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
696127000169	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696127000170	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
696127000171	gluconate 5-dehydrogenase; Provisional; Region: PRK08213
696127000172	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000173	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
696127000174	intersubunit interface [polypeptide binding]; other site
696127000175	active site
696127000176	Zn2+ binding site [ion binding]; other site
696127000177	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
696127000178	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
696127000179	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
696127000180	F0F1 ATP synthase subunit C; Validated; Region: PRK07558
696127000181	ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Region: ATP_synt_6_or_A; TIGR01131
696127000182	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
696127000183	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
696127000184	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
696127000185	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
696127000186	Na binding site [ion binding]; other site
696127000187	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
696127000188	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
696127000189	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696127000190	FeS/SAM binding site; other site
696127000191	TRAM domain; Region: TRAM; pfam01938
696127000192	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
696127000193	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
696127000194	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
696127000195	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
696127000196	active site
696127000197	multimer interface [polypeptide binding]; other site
696127000198	enolase; Provisional; Region: eno; PRK00077
696127000199	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
696127000200	dimer interface [polypeptide binding]; other site
696127000201	metal binding site [ion binding]; metal-binding site
696127000202	substrate binding pocket [chemical binding]; other site
696127000203	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
696127000204	Glycoprotease family; Region: Peptidase_M22; pfam00814
696127000205	Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478
696127000206	lysyl-tRNA synthetase; Reviewed; Region: lysK; PRK00750
696127000207	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
696127000208	active site
696127000209	nucleotide binding site [chemical binding]; other site
696127000210	HIGH motif; other site
696127000211	KMSKS motif; other site
696127000212	delta-aminolevulinic acid dehydratase; Validated; Region: PRK09283
696127000213	dimer interface [polypeptide binding]; other site
696127000214	active site
696127000215	Schiff base residues; other site
696127000216	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000217	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696127000218	NADH dehydrogenase subunit E; Validated; Region: PRK07539
696127000219	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
696127000220	putative dimer interface [polypeptide binding]; other site
696127000221	[2Fe-2S] cluster binding site [ion binding]; other site
696127000222	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
696127000223	NADH dehydrogenase subunit D; Validated; Region: PRK06075
696127000224	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
696127000225	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
696127000226	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
696127000227	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
696127000228	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
696127000229	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
696127000230	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
696127000231	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
696127000232	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
696127000233	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
696127000234	NADH dehydrogenase subunit 6; Provisional; Region: ND6; MTH00213
696127000235	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
696127000236	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696127000237	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696127000238	catalytic residue [active]
696127000239	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
696127000240	UbiA prenyltransferase family; Region: UbiA; pfam01040
696127000241	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
696127000242	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
696127000243	AAA domain; Region: AAA_26; pfam13500
696127000244	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
696127000245	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
696127000246	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696127000247	S-adenosylmethionine binding site [chemical binding]; other site
696127000248	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
696127000249	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
696127000250	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
696127000251	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
696127000252	catalytic residue [active]
696127000253	biotin synthase; Region: bioB; TIGR00433
696127000254	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696127000255	FeS/SAM binding site; other site
696127000256	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
696127000257	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
696127000258	30S subunit binding site; other site
696127000259	elongation factor P; Validated; Region: PRK00529
696127000260	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
696127000261	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
696127000262	RNA binding site [nucleotide binding]; other site
696127000263	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
696127000264	RNA binding site [nucleotide binding]; other site
696127000265	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
696127000266	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
696127000267	putative GSH binding site [chemical binding]; other site
696127000268	catalytic residues [active]
696127000269	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
696127000270	Putative transmembrane protein (Alph_Pro_TM); Region: Alph_Pro_TM; cl09826
696127000271	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
696127000272	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
696127000273	RNA polymerase-binding protein DksA; Region: dksA; TIGR02420
696127000274	recombination protein RecR; Reviewed; Region: recR; PRK00076
696127000275	RecR protein; Region: RecR; pfam02132
696127000276	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
696127000277	putative active site [active]
696127000278	putative metal-binding site [ion binding]; other site
696127000279	tetramer interface [polypeptide binding]; other site
696127000280	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
696127000281	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
696127000282	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
696127000283	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12691
696127000284	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
696127000285	SAF-like; Region: SAF_2; pfam13144
696127000286	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
696127000287	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
696127000288	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
696127000289	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK12788
696127000290	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
696127000291	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
696127000292	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
696127000293	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
696127000294	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
696127000295	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
696127000296	active site
696127000297	dimer interface [polypeptide binding]; other site
696127000298	motif 1; other site
696127000299	motif 2; other site
696127000300	motif 3; other site
696127000301	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
696127000302	anticodon binding site; other site
696127000303	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
696127000304	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
696127000305	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
696127000306	FG-GAP repeat; Region: FG-GAP; cl15299
696127000307	GTPase CgtA; Reviewed; Region: obgE; PRK12299
696127000308	GTP1/OBG; Region: GTP1_OBG; pfam01018
696127000309	Obg GTPase; Region: Obg; cd01898
696127000310	G1 box; other site
696127000311	GTP/Mg2+ binding site [chemical binding]; other site
696127000312	Switch I region; other site
696127000313	G2 box; other site
696127000314	G3 box; other site
696127000315	Switch II region; other site
696127000316	G4 box; other site
696127000317	G5 box; other site
696127000318	putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; Validated; Region: PRK06567
696127000319	FAD/NAD binding domain (electron transfer subunit) of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate...; Region: DHOD_e_trans_like; cd06192
696127000320	FAD binding pocket [chemical binding]; other site
696127000321	FAD binding motif [chemical binding]; other site
696127000322	phosphate binding motif [ion binding]; other site
696127000323	beta-alpha-beta structure motif; other site
696127000324	NAD binding pocket [chemical binding]; other site
696127000325	Iron coordination center [ion binding]; other site
696127000326	SRP54-type protein, GTPase domain; Region: SRP54; smart00962
696127000327	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
696127000328	P loop; other site
696127000329	GTP binding site [chemical binding]; other site
696127000330	Predicted membrane protein (DUF2335); Region: DUF2335; pfam10097
696127000331	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000332	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK06585
696127000333	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
696127000334	NAD synthetase; Provisional; Region: PRK13981
696127000335	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
696127000336	multimer interface [polypeptide binding]; other site
696127000337	active site
696127000338	catalytic triad [active]
696127000339	protein interface 1 [polypeptide binding]; other site
696127000340	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
696127000341	homodimer interface [polypeptide binding]; other site
696127000342	NAD binding pocket [chemical binding]; other site
696127000343	ATP binding pocket [chemical binding]; other site
696127000344	Mg binding site [ion binding]; other site
696127000345	active-site loop [active]
696127000346	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
696127000347	active site
696127000348	rpsU-divergently transcribed protein; Region: diverge_rpsU; TIGR02396
696127000349	COQ9; Region: COQ9; pfam08511
696127000350	Protein of unknown function (DUF721); Region: DUF721; pfam05258
696127000351	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14468
696127000352	Protein of unknown function (DUF721); Region: DUF721; pfam05258
696127000353	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
696127000354	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
696127000355	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
696127000356	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
696127000357	polyhydroxyalkanoate synthesis repressor PhaR; Region: PHA_reg_PhaR; TIGR01848
696127000358	PHB/PHA accumulation regulator DNA-binding domain; Region: PHB_acc_N; pfam07879
696127000359	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
696127000360	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
696127000361	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000362	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
696127000363	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
696127000364	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
696127000365	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
696127000366	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
696127000367	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
696127000368	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
696127000369	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
696127000370	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
696127000371	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
696127000372	protein binding site [polypeptide binding]; other site
696127000373	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
696127000374	putative substrate binding region [chemical binding]; other site
696127000375	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
696127000376	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
696127000377	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
696127000378	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
696127000379	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
696127000380	Surface antigen; Region: Bac_surface_Ag; pfam01103
696127000381	Surface antigen; Region: Bac_surface_Ag; pfam01103
696127000382	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
696127000383	SurA N-terminal domain; Region: SurA_N_3; cl07813
696127000384	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
696127000385	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
696127000386	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
696127000387	hypothetical protein; Reviewed; Region: PRK12497
696127000388	TLC ATP/ADP transporter; Region: TLC; pfam03219
696127000389	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
696127000390	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
696127000391	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
696127000392	rod shape-determining protein MreB; Provisional; Region: PRK13927
696127000393	MreB and similar proteins; Region: MreB_like; cd10225
696127000394	nucleotide binding site [chemical binding]; other site
696127000395	Mg binding site [ion binding]; other site
696127000396	putative protofilament interaction site [polypeptide binding]; other site
696127000397	RodZ interaction site [polypeptide binding]; other site
696127000398	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696127000399	FeS/SAM binding site; other site
696127000400	HemN C-terminal domain; Region: HemN_C; pfam06969
696127000401	Iron-sulfur cluster assembly accessory protein; Region: TIGR00049
696127000402	4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase [Lipid metabolism]; Region: IspE; COG1947
696127000403	transcription termination factor Rho; Provisional; Region: rho; PRK09376
696127000404	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
696127000405	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
696127000406	RNA binding site [nucleotide binding]; other site
696127000407	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
696127000408	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
696127000409	multimer interface [polypeptide binding]; other site
696127000410	Walker A motif; other site
696127000411	Walker A motif; other site
696127000412	ATP binding site [chemical binding]; other site
696127000413	Walker B motif; other site
696127000414	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
696127000415	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
696127000416	catalytic site [active]
696127000417	G-X2-G-X-G-K; other site
696127000418	glutathione synthetase; Provisional; Region: PRK05246
696127000419	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
696127000420	ATP-grasp domain; Region: ATP-grasp_4; cl17255
696127000421	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
696127000422	Ligand Binding Site [chemical binding]; other site
696127000423	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
696127000424	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
696127000425	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
696127000426	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696127000427	putative substrate translocation pore; other site
696127000428	multifunctional aminopeptidase A; Provisional; Region: PRK00913
696127000429	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
696127000430	interface (dimer of trimers) [polypeptide binding]; other site
696127000431	Substrate-binding/catalytic site; other site
696127000432	Zn-binding sites [ion binding]; other site
696127000433	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
696127000434	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696127000435	S-adenosylmethionine binding site [chemical binding]; other site
696127000436	IPP transferase; Region: IPPT; pfam01715
696127000437	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
696127000438	Part of AAA domain; Region: AAA_19; pfam13245
696127000439	UvrD-like helicase C-terminal domain; Region: UvrD_C; pfam13361
696127000440	Family description; Region: UvrD_C_2; pfam13538
696127000441	Trp repressor protein; Region: Trp_repressor; cl17266
696127000442	hypothetical protein; Validated; Region: PRK00228
696127000443	Coproporphyrinogen III oxidase [Coenzyme metabolism]; Region: HemF; COG0408
696127000444	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; cl17752
696127000445	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
696127000446	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
696127000447	5S rRNA interface [nucleotide binding]; other site
696127000448	CTC domain interface [polypeptide binding]; other site
696127000449	L16 interface [polypeptide binding]; other site
696127000450	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
696127000451	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
696127000452	active site
696127000453	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
696127000454	dimer interface [polypeptide binding]; other site
696127000455	substrate binding site [chemical binding]; other site
696127000456	catalytic residues [active]
696127000457	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
696127000458	Permease; Region: Permease; pfam02405
696127000459	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
696127000460	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696127000461	Walker A/P-loop; other site
696127000462	ATP binding site [chemical binding]; other site
696127000463	Q-loop/lid; other site
696127000464	ABC transporter signature motif; other site
696127000465	Walker B; other site
696127000466	D-loop; other site
696127000467	H-loop/switch region; other site
696127000468	Uncharacterized membrane-bound protein [Function unknown]; Region: COG3898
696127000469	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
696127000470	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
696127000471	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
696127000472	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
696127000473	thymidylate kinase; Validated; Region: tmk; PRK00698
696127000474	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
696127000475	TMP-binding site; other site
696127000476	ATP-binding site [chemical binding]; other site
696127000477	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
696127000478	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
696127000479	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
696127000480	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
696127000481	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
696127000482	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
696127000483	Walker A/P-loop; other site
696127000484	ATP binding site [chemical binding]; other site
696127000485	Q-loop/lid; other site
696127000486	ABC transporter signature motif; other site
696127000487	Walker B; other site
696127000488	D-loop; other site
696127000489	H-loop/switch region; other site
696127000490	TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: Imp; COG2358
696127000491	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
696127000492	hypothetical protein; Validated; Region: PRK00110
696127000493	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
696127000494	active site
696127000495	putative DNA-binding cleft [nucleotide binding]; other site
696127000496	dimer interface [polypeptide binding]; other site
696127000497	cell division protein FtsZ; Validated; Region: PRK09330
696127000498	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
696127000499	nucleotide binding site [chemical binding]; other site
696127000500	SulA interaction site; other site
696127000501	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
696127000502	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
696127000503	RNA binding surface [nucleotide binding]; other site
696127000504	DEAD-like helicases superfamily; Region: DEXDc; smart00487
696127000505	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696127000506	ATP binding site [chemical binding]; other site
696127000507	putative Mg++ binding site [ion binding]; other site
696127000508	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000509	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
696127000510	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
696127000511	dimer interface [polypeptide binding]; other site
696127000512	active site
696127000513	CoA binding pocket [chemical binding]; other site
696127000514	putative phosphate acyltransferase; Provisional; Region: PRK05331
696127000515	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
696127000516	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
696127000517	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
696127000518	putative tRNA-binding site [nucleotide binding]; other site
696127000519	B3/4 domain; Region: B3_4; pfam03483
696127000520	tRNA synthetase B5 domain; Region: B5; smart00874
696127000521	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
696127000522	dimer interface [polypeptide binding]; other site
696127000523	motif 1; other site
696127000524	motif 3; other site
696127000525	motif 2; other site
696127000526	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
696127000527	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
696127000528	ParB-like nuclease domain; Region: ParBc; pfam02195
696127000529	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
696127000530	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; cl17726
696127000531	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
696127000532	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
696127000533	P-loop; other site
696127000534	Magnesium ion binding site [ion binding]; other site
696127000535	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
696127000536	Magnesium ion binding site [ion binding]; other site
696127000537	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
696127000538	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
696127000539	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
696127000540	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
696127000541	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
696127000542	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696127000543	S-adenosylmethionine binding site [chemical binding]; other site
696127000544	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
696127000545	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
696127000546	substrate binding site [chemical binding]; other site
696127000547	active site
696127000548	replicative DNA helicase; Provisional; Region: PRK09165
696127000549	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
696127000550	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
696127000551	Walker A motif; other site
696127000552	ATP binding site [chemical binding]; other site
696127000553	Walker B motif; other site
696127000554	DNA binding loops [nucleotide binding]
696127000555	recombinase A; Provisional; Region: recA; PRK09354
696127000556	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
696127000557	hexamer interface [polypeptide binding]; other site
696127000558	Walker A motif; other site
696127000559	ATP binding site [chemical binding]; other site
696127000560	Walker B motif; other site
696127000561	pyruvate phosphate dikinase; Provisional; Region: PRK09279
696127000562	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
696127000563	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
696127000564	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
696127000565	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
696127000566	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
696127000567	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
696127000568	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
696127000569	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
696127000570	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
696127000571	SEC-C motif; Region: SEC-C; pfam02810
696127000572	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
696127000573	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
696127000574	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
696127000575	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
696127000576	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
696127000577	DNA binding site [nucleotide binding]
696127000578	catalytic residue [active]
696127000579	H2TH interface [polypeptide binding]; other site
696127000580	putative catalytic residues [active]
696127000581	turnover-facilitating residue; other site
696127000582	intercalation triad [nucleotide binding]; other site
696127000583	8OG recognition residue [nucleotide binding]; other site
696127000584	putative reading head residues; other site
696127000585	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
696127000586	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
696127000587	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
696127000588	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
696127000589	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
696127000590	Competence protein; Region: Competence; cl00471
696127000591	Domain of unknown function DUF20; Region: UPF0118; pfam01594
696127000592	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
696127000593	Uncharacterized protein conserved in bacteria (DUF2312); Region: DUF2312; cl11480
696127000594	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000595	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
696127000596	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
696127000597	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696127000598	FeS/SAM binding site; other site
696127000599	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
696127000600	Ribosomal prokaryotic L21 protein; Region: Ribosomal_L21p; cl00382
696127000601	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
696127000602	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
696127000603	active site
696127000604	catalytic site [active]
696127000605	putative DNA binding site [nucleotide binding]; other site
696127000606	GIY-YIG motif/motif A; other site
696127000607	metal binding site [ion binding]; metal-binding site
696127000608	UvrB/uvrC motif; Region: UVR; pfam02151
696127000609	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
696127000610	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
696127000611	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
696127000612	FHIPEP family; Region: FHIPEP; pfam00771
696127000613	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
696127000614	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
696127000615	helix-hairpin-helix signature motif; other site
696127000616	substrate binding pocket [chemical binding]; other site
696127000617	active site
696127000618	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
696127000619	Membrane fusogenic activity; Region: BMFP; pfam04380
696127000620	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
696127000621	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
696127000622	Peptidase family M23; Region: Peptidase_M23; pfam01551
696127000623	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
696127000624	Peptidase family M23; Region: Peptidase_M23; pfam01551
696127000625	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
696127000626	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
696127000627	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
696127000628	trimerization site [polypeptide binding]; other site
696127000629	active site
696127000630	cysteine desulfurase; Provisional; Region: PRK14012
696127000631	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
696127000632	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
696127000633	catalytic residue [active]
696127000634	Predicted transcriptional regulator [Transcription]; Region: COG1959
696127000635	Transcriptional regulator; Region: Rrf2; cl17282
696127000636	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
696127000637	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
696127000638	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
696127000639	catalytic residue [active]
696127000640	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
696127000641	Serine hydrolase (FSH1); Region: FSH1; pfam03959
696127000642	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
696127000643	RmuC family; Region: RmuC; pfam02646
696127000644	triosephosphate isomerase; Provisional; Region: PRK14567
696127000645	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
696127000646	substrate binding site [chemical binding]; other site
696127000647	dimer interface [polypeptide binding]; other site
696127000648	catalytic triad [active]
696127000649	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000650	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
696127000651	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
696127000652	active site
696127000653	HIGH motif; other site
696127000654	KMSKS motif; other site
696127000655	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
696127000656	tRNA binding surface [nucleotide binding]; other site
696127000657	anticodon binding site; other site
696127000658	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
696127000659	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
696127000660	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
696127000661	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
696127000662	trimer interface [polypeptide binding]; other site
696127000663	active site
696127000664	substrate binding site [chemical binding]; other site
696127000665	CoA binding site [chemical binding]; other site
696127000666	dihydrodipicolinate synthase; Region: dapA; TIGR00674
696127000667	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
696127000668	dimer interface [polypeptide binding]; other site
696127000669	active site
696127000670	catalytic residue [active]
696127000671	dihydrodipicolinate reductase; Provisional; Region: PRK00048
696127000672	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
696127000673	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
696127000674	Protein of unknown function (DUF1013); Region: DUF1013; cl11533
696127000675	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
696127000676	Na binding site [ion binding]; other site
696127000677	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
696127000678	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696127000679	Walker A/P-loop; other site
696127000680	ATP binding site [chemical binding]; other site
696127000681	Q-loop/lid; other site
696127000682	ABC transporter signature motif; other site
696127000683	Walker B; other site
696127000684	D-loop; other site
696127000685	H-loop/switch region; other site
696127000686	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
696127000687	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
696127000688	Bacterial export proteins, family 1; Region: Bac_export_1; cl00734
696127000689	Global regulator protein family; Region: CsrA; cl00670
696127000690	aconitate hydratase; Validated; Region: PRK09277
696127000691	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
696127000692	substrate binding site [chemical binding]; other site
696127000693	ligand binding site [chemical binding]; other site
696127000694	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
696127000695	substrate binding site [chemical binding]; other site
696127000696	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000697	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
696127000698	Zinc-finger domain; Region: zf-CHCC; cl01821
696127000699	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
696127000700	nucleotide binding site [chemical binding]; other site
696127000701	Type III pantothenate kinase; Region: Pan_kinase; cl17198
696127000702	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
696127000703	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
696127000704	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
696127000705	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
696127000706	amino acid transporter; Region: 2A0306; TIGR00909
696127000707	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
696127000708	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
696127000709	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
696127000710	putative active site [active]
696127000711	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
696127000712	Recombination protein O N terminal; Region: RecO_N; pfam11967
696127000713	Recombination protein O C terminal; Region: RecO_C; pfam02565
696127000714	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
696127000715	HlyD family secretion protein; Region: HlyD_3; pfam13437
696127000716	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
696127000717	Family description; Region: VCBS; pfam13517
696127000718	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
696127000719	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
696127000720	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
696127000721	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
696127000722	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
696127000723	Flavoprotein; Region: Flavoprotein; pfam02441
696127000724	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
696127000725	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
696127000726	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
696127000727	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5375
696127000728	co-chaperone HscB; Provisional; Region: hscB; PRK05014
696127000729	DnaJ domain; Region: DnaJ; pfam00226
696127000730	HSP70 interaction site [polypeptide binding]; other site
696127000731	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
696127000732	MreB/Mbl protein; Region: MreB_Mbl; pfam06723
696127000733	nucleotide binding site [chemical binding]; other site
696127000734	putative NEF/HSP70 interaction site [polypeptide binding]; other site
696127000735	SBD interface [polypeptide binding]; other site
696127000736	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
696127000737	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696127000738	Mg2+ binding site [ion binding]; other site
696127000739	G-X-G motif; other site
696127000740	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
696127000741	ATP binding site [chemical binding]; other site
696127000742	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
696127000743	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000744	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
696127000745	IHF dimer interface [polypeptide binding]; other site
696127000746	IHF - DNA interface [nucleotide binding]; other site
696127000747	Sulfatase; Region: Sulfatase; pfam00884
696127000748	TLC ATP/ADP transporter; Region: TLC; cl03940
696127000749	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
696127000750	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
696127000751	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
696127000752	Mechanosensitive ion channel; Region: MS_channel; pfam00924
696127000753	Uncharacterized BCR, COG1636; Region: DUF208; cl17782
696127000754	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
696127000755	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
696127000756	trmE is a tRNA modification GTPase; Region: trmE; cd04164
696127000757	G1 box; other site
696127000758	GTP/Mg2+ binding site [chemical binding]; other site
696127000759	Switch I region; other site
696127000760	G2 box; other site
696127000761	Switch II region; other site
696127000762	G3 box; other site
696127000763	G4 box; other site
696127000764	G5 box; other site
696127000765	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000766	Glutamate-cysteine ligase; Region: GshA; pfam08886
696127000767	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
696127000768	RNA methyltransferase, RsmE family; Region: TIGR00046
696127000769	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
696127000770	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
696127000771	GSH binding site (G-site) [chemical binding]; other site
696127000772	C-terminal domain interface [polypeptide binding]; other site
696127000773	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cd00299
696127000774	N-terminal domain interface [polypeptide binding]; other site
696127000775	dimer interface [polypeptide binding]; other site
696127000776	substrate binding pocket (H-site) [chemical binding]; other site
696127000777	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
696127000778	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
696127000779	PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_6; cd03396
696127000780	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
696127000781	active site
696127000782	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
696127000783	chaperone protein DnaJ; Provisional; Region: PRK10767
696127000784	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
696127000785	HSP70 interaction site [polypeptide binding]; other site
696127000786	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
696127000787	substrate binding site [polypeptide binding]; other site
696127000788	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
696127000789	Zn binding sites [ion binding]; other site
696127000790	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
696127000791	dimer interface [polypeptide binding]; other site
696127000792	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000793	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
696127000794	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
696127000795	putative active site [active]
696127000796	putative PHP Thumb interface [polypeptide binding]; other site
696127000797	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
696127000798	generic binding surface II; other site
696127000799	generic binding surface I; other site
696127000800	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
696127000801	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
696127000802	S-adenosylmethionine binding site [chemical binding]; other site
696127000803	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09102
696127000804	Class I ribonucleotide reductase; Region: RNR_I; cd01679
696127000805	active site
696127000806	dimer interface [polypeptide binding]; other site
696127000807	catalytic residues [active]
696127000808	effector binding site; other site
696127000809	R2 peptide binding site; other site
696127000810	Kinase/pyrophosphorylase; Region: Kinase-PPPase; pfam03618
696127000811	FtsH Extracellular; Region: FtsH_ext; pfam06480
696127000812	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
696127000813	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696127000814	Walker A motif; other site
696127000815	ATP binding site [chemical binding]; other site
696127000816	Walker B motif; other site
696127000817	arginine finger; other site
696127000818	Peptidase family M41; Region: Peptidase_M41; pfam01434
696127000819	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000820	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
696127000821	Preprotein translocase subunit SecB; Region: SecB; pfam02556
696127000822	SecA binding site; other site
696127000823	Preprotein binding site; other site
696127000824	Tim44-like domain; Region: Tim44; pfam04280
696127000825	MltA specific insert domain; Region: MltA; smart00925
696127000826	3D domain; Region: 3D; pfam06725
696127000827	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
696127000828	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
696127000829	active site clefts [active]
696127000830	zinc binding site [ion binding]; other site
696127000831	dimer interface [polypeptide binding]; other site
696127000832	DNA gyrase subunit A; Validated; Region: PRK05560
696127000833	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
696127000834	CAP-like domain; other site
696127000835	active site
696127000836	primary dimer interface [polypeptide binding]; other site
696127000837	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
696127000838	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
696127000839	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
696127000840	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
696127000841	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
696127000842	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
696127000843	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
696127000844	Bacterial protein of unknown function (HtrL_YibB); Region: HtrL_YibB; cl08171
696127000845	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
696127000846	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
696127000847	Surface antigen [Cell envelope biogenesis, outer membrane]; Region: LipA; COG4520
696127000848	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08159
696127000849	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
696127000850	NAD binding site [chemical binding]; other site
696127000851	homotetramer interface [polypeptide binding]; other site
696127000852	homodimer interface [polypeptide binding]; other site
696127000853	substrate binding site [chemical binding]; other site
696127000854	active site
696127000855	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); Region: PCMT; pfam01135
696127000856	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696127000857	S-adenosylmethionine binding site [chemical binding]; other site
696127000858	ribonuclease PH; Reviewed; Region: rph; PRK00173
696127000859	Ribonuclease PH; Region: RNase_PH_bact; cd11362
696127000860	hexamer interface [polypeptide binding]; other site
696127000861	active site
696127000862	Thioredoxin; Region: Thioredoxin_4; pfam13462
696127000863	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
696127000864	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
696127000865	RNA/DNA hybrid binding site [nucleotide binding]; other site
696127000866	active site
696127000867	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
696127000868	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
696127000869	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
696127000870	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
696127000871	DsbD alpha interface [polypeptide binding]; other site
696127000872	catalytic residues [active]
696127000873	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127000874	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
696127000875	active site
696127000876	Cell division protein ZapA; Region: ZapA; cl01146
696127000877	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
696127000878	seryl-tRNA synthetase; Provisional; Region: PRK05431
696127000879	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
696127000880	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
696127000881	dimer interface [polypeptide binding]; other site
696127000882	active site
696127000883	motif 1; other site
696127000884	motif 2; other site
696127000885	motif 3; other site
696127000886	RDD family; Region: RDD; pfam06271
696127000887	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
696127000888	GTP-binding protein Der; Reviewed; Region: PRK00093
696127000889	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
696127000890	G1 box; other site
696127000891	GTP/Mg2+ binding site [chemical binding]; other site
696127000892	Switch I region; other site
696127000893	G2 box; other site
696127000894	Switch II region; other site
696127000895	G3 box; other site
696127000896	G4 box; other site
696127000897	G5 box; other site
696127000898	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
696127000899	G1 box; other site
696127000900	GTP/Mg2+ binding site [chemical binding]; other site
696127000901	Switch I region; other site
696127000902	G2 box; other site
696127000903	G3 box; other site
696127000904	Switch II region; other site
696127000905	G4 box; other site
696127000906	G5 box; other site
696127000907	alkylhydroperoxidase, AhpD family; Region: ahpD; TIGR00777
696127000908	alkylhydroperoxidase AhpD family core domain; Region: ahpD_dom; TIGR00778
696127000909	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
696127000910	Fatty acid desaturase; Region: FA_desaturase; pfam00487
696127000911	Di-iron ligands [ion binding]; other site
696127000912	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
696127000913	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
696127000914	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
696127000915	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
696127000916	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
696127000917	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
696127000918	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
696127000919	FliG C-terminal domain; Region: FliG_C; pfam01706
696127000920	Flagellar assembly protein FliH; Region: FliH; pfam02108
696127000921	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
696127000922	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
696127000923	active site
696127000924	KMSKS motif; other site
696127000925	Riboflavin kinase; Region: Flavokinase; pfam01687
696127000926	RNA polymerase sigma-54 factor; Region: rpoN_sigma; TIGR02395
696127000927	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
696127000928	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
696127000929	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
696127000930	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
696127000931	catalytic residues [active]
696127000932	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696127000933	S-adenosylmethionine binding site [chemical binding]; other site
696127000934	VacJ like lipoprotein; Region: VacJ; cl01073
696127000935	Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; pfam05494
696127000936	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696127000937	Radical SAM superfamily; Region: Radical_SAM; pfam04055
696127000938	FeS/SAM binding site; other site
696127000939	rod shape-determining protein MreC; Provisional; Region: PRK13922
696127000940	rod shape-determining protein MreC; Region: MreC; pfam04085
696127000941	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
696127000942	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
696127000943	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
696127000944	dimer interface [polypeptide binding]; other site
696127000945	motif 1; other site
696127000946	active site
696127000947	motif 2; other site
696127000948	motif 3; other site
696127000949	FixH; Region: FixH; pfam05751
696127000950	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
696127000951	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
696127000952	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
696127000953	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
696127000954	Mg++ binding site [ion binding]; other site
696127000955	putative catalytic motif [active]
696127000956	putative substrate binding site [chemical binding]; other site
696127000957	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01390
696127000958	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
696127000959	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
696127000960	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
696127000961	phosphoglyceromutase; Provisional; Region: PRK05434
696127000962	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
696127000963	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696127000964	active site
696127000965	phosphorylation site [posttranslational modification]
696127000966	intermolecular recognition site; other site
696127000967	dimerization interface [polypeptide binding]; other site
696127000968	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696127000969	Walker A motif; other site
696127000970	ATP binding site [chemical binding]; other site
696127000971	Walker B motif; other site
696127000972	arginine finger; other site
696127000973	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
696127000974	Oligomerisation domain; Region: Oligomerisation; pfam02410
696127000975	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
696127000976	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
696127000977	active site
696127000978	(T/H)XGH motif; other site
696127000979	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
696127000980	Found in ATP-dependent protease La (LON); Region: LON; smart00464
696127000981	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696127000982	Walker A motif; other site
696127000983	ATP binding site [chemical binding]; other site
696127000984	Walker B motif; other site
696127000985	arginine finger; other site
696127000986	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
696127000987	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
696127000988	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
696127000989	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
696127000990	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
696127000991	Type IV secretory system Conjugative DNA transfer; Region: T4SS-DNA_transf; pfam02534
696127000992	The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome. They contain an ATP binding domain. VirD4 is involved in DNA transfer...; Region: TraG_VirD4; cd01126
696127000993	Walker A motif; other site
696127000994	ATP binding site [chemical binding]; other site
696127000995	Walker B motif; other site
696127000996	type IV secretion system ATPase VirB11; Provisional; Region: PRK13900
696127000997	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
696127000998	hexamer interface [polypeptide binding]; other site
696127000999	Walker B motif; other site
696127001000	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
696127001001	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
696127001002	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
696127001003	VirB7 interaction site; other site
696127001004	VirB8 protein; Region: VirB8; pfam04335
696127001005	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
696127001006	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
696127001007	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
696127001008	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs; Region: NDUFA9_like_SDR_a; cd05271
696127001009	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
696127001010	putative NAD(P) binding site [chemical binding]; other site
696127001011	active site
696127001012	NADH ubiquinone oxidoreductase subunit NDUFA12; Region: NDUFA12; cl01534
696127001013	mce related protein; Region: MCE; pfam02470
696127001014	Uncharacterized protein conserved in bacteria (DUF2155); Region: DUF2155; cl01970
696127001015	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05389
696127001016	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
696127001017	RNA binding site [nucleotide binding]; other site
696127001018	active site
696127001019	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
696127001020	16S/18S rRNA binding site [nucleotide binding]; other site
696127001021	S13e-L30e interaction site [polypeptide binding]; other site
696127001022	25S rRNA binding site [nucleotide binding]; other site
696127001023	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
696127001024	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
696127001025	trimer interface [polypeptide binding]; other site
696127001026	RNase E interface [polypeptide binding]; other site
696127001027	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
696127001028	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
696127001029	RNase E interface [polypeptide binding]; other site
696127001030	trimer interface [polypeptide binding]; other site
696127001031	active site
696127001032	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
696127001033	putative nucleic acid binding region [nucleotide binding]; other site
696127001034	G-X-X-G motif; other site
696127001035	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
696127001036	RNA binding site [nucleotide binding]; other site
696127001037	domain interface; other site
696127001038	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
696127001039	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
696127001040	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
696127001041	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
696127001042	inhibitor-cofactor binding pocket; inhibition site
696127001043	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696127001044	catalytic residue [active]
696127001045	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
696127001046	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
696127001047	dimerization interface 3.5A [polypeptide binding]; other site
696127001048	active site
696127001049	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
696127001050	metal binding site 2 [ion binding]; metal-binding site
696127001051	putative DNA binding helix; other site
696127001052	metal binding site 1 [ion binding]; metal-binding site
696127001053	dimer interface [polypeptide binding]; other site
696127001054	structural Zn2+ binding site [ion binding]; other site
696127001055	HAMP domain; Region: HAMP; pfam00672
696127001056	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696127001057	dimer interface [polypeptide binding]; other site
696127001058	phosphorylation site [posttranslational modification]
696127001059	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696127001060	ATP binding site [chemical binding]; other site
696127001061	Mg2+ binding site [ion binding]; other site
696127001062	G-X-G motif; other site
696127001063	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
696127001064	uncharacterized subgroup of the Escherichia coli Mg2+ transporter CorA_like subfamily; Region: EcCorA-like_u1; cd12837
696127001065	Cl binding site [ion binding]; other site
696127001066	oligomer interface [polypeptide binding]; other site
696127001067	flagellar motor protein MotA; Validated; Region: PRK09110
696127001068	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
696127001069	active site
696127001070	substrate binding site [chemical binding]; other site
696127001071	catalytic site [active]
696127001072	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
696127001073	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
696127001074	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
696127001075	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696127001076	S-adenosylmethionine binding site [chemical binding]; other site
696127001077	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001078	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001079	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
696127001080	Fe-S cluster binding site [ion binding]; other site
696127001081	active site
696127001082	translation initiation factor IF-2; Region: IF-2; TIGR00487
696127001083	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
696127001084	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
696127001085	G1 box; other site
696127001086	putative GEF interaction site [polypeptide binding]; other site
696127001087	GTP/Mg2+ binding site [chemical binding]; other site
696127001088	Switch I region; other site
696127001089	G2 box; other site
696127001090	G3 box; other site
696127001091	Switch II region; other site
696127001092	G4 box; other site
696127001093	G5 box; other site
696127001094	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
696127001095	Translation-initiation factor 2; Region: IF-2; pfam11987
696127001096	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
696127001097	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
696127001098	NusA N-terminal domain; Region: NusA_N; pfam08529
696127001099	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
696127001100	RNA binding site [nucleotide binding]; other site
696127001101	homodimer interface [polypeptide binding]; other site
696127001102	NusA-like KH domain; Region: KH_5; pfam13184
696127001103	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
696127001104	G-X-X-G motif; other site
696127001105	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
696127001106	ribosome maturation protein RimP; Reviewed; Region: PRK00092
696127001107	Sm and related proteins; Region: Sm_like; cl00259
696127001108	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
696127001109	putative RNA binding site [nucleotide binding]; other site
696127001110	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
696127001111	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
696127001112	putative catalytic site [active]
696127001113	putative phosphate binding site [ion binding]; other site
696127001114	active site
696127001115	metal binding site A [ion binding]; metal-binding site
696127001116	DNA binding site [nucleotide binding]
696127001117	putative AP binding site [nucleotide binding]; other site
696127001118	putative metal binding site B [ion binding]; other site
696127001119	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
696127001120	active site
696127001121	HslU subunit interaction site [polypeptide binding]; other site
696127001122	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
696127001123	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
696127001124	active site
696127001125	HIGH motif; other site
696127001126	dimer interface [polypeptide binding]; other site
696127001127	KMSKS motif; other site
696127001128	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
696127001129	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
696127001130	CDP-alcohol phosphatidyltransferase 2; Region: CDP-OH_P_tran_2; pfam08009
696127001131	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
696127001132	MviN-like protein; Region: MVIN; pfam03023
696127001133	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
696127001134	dimer interface [polypeptide binding]; other site
696127001135	putative radical transfer pathway; other site
696127001136	diiron center [ion binding]; other site
696127001137	tyrosyl radical; other site
696127001138	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
696127001139	putative ligand binding site [chemical binding]; other site
696127001140	zinc binding site [ion binding]; other site
696127001141	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
696127001142	TM-ABC transporter signature motif; other site
696127001143	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
696127001144	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
696127001145	Walker A/P-loop; other site
696127001146	ATP binding site [chemical binding]; other site
696127001147	Q-loop/lid; other site
696127001148	ABC transporter signature motif; other site
696127001149	Walker B; other site
696127001150	D-loop; other site
696127001151	H-loop/switch region; other site
696127001152	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
696127001153	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
696127001154	ligand binding site [chemical binding]; other site
696127001155	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
696127001156	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
696127001157	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK08664
696127001158	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
696127001159	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
696127001160	nucleotide binding site [chemical binding]; other site
696127001161	substrate binding site [chemical binding]; other site
696127001162	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
696127001163	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
696127001164	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
696127001165	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
696127001166	homodimer interface [polypeptide binding]; other site
696127001167	substrate-cofactor binding pocket; other site
696127001168	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696127001169	catalytic residue [active]
696127001170	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
696127001171	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
696127001172	Glycyl-tRNA synthetase beta subunit; Region: tRNA_synt_2f; pfam02092
696127001173	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
696127001174	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
696127001175	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
696127001176	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
696127001177	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
696127001178	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
696127001179	putative homodimer interface [polypeptide binding]; other site
696127001180	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
696127001181	heterodimer interface [polypeptide binding]; other site
696127001182	homodimer interface [polypeptide binding]; other site
696127001183	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
696127001184	L7/L12 interface [polypeptide binding]; other site
696127001185	23S rRNA interface [nucleotide binding]; other site
696127001186	L25 interface [polypeptide binding]; other site
696127001187	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
696127001188	mRNA/rRNA interface [nucleotide binding]; other site
696127001189	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
696127001190	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
696127001191	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
696127001192	L11 interface [polypeptide binding]; other site
696127001193	putative EF-Tu interaction site [polypeptide binding]; other site
696127001194	putative EF-G interaction site [polypeptide binding]; other site
696127001195	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
696127001196	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
696127001197	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
696127001198	RPB12 interaction site [polypeptide binding]; other site
696127001199	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
696127001200	RPB3 interaction site [polypeptide binding]; other site
696127001201	RPB1 interaction site [polypeptide binding]; other site
696127001202	RPB11 interaction site [polypeptide binding]; other site
696127001203	RPB10 interaction site [polypeptide binding]; other site
696127001204	DNA-directed RNA polymerase subunit gamma; Provisional; Region: rpoC1; PRK02625
696127001205	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
696127001206	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
696127001207	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
696127001208	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001209	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
696127001210	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
696127001211	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
696127001212	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
696127001213	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
696127001214	active site
696127001215	phosphorylation site [posttranslational modification]
696127001216	dimerization interface [polypeptide binding]; other site
696127001217	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696127001218	Walker A motif; other site
696127001219	ATP binding site [chemical binding]; other site
696127001220	Walker B motif; other site
696127001221	arginine finger; other site
696127001222	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
696127001223	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
696127001224	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
696127001225	Competence-damaged protein; Region: CinA; pfam02464
696127001226	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
696127001227	tetramer interfaces [polypeptide binding]; other site
696127001228	binuclear metal-binding site [ion binding]; other site
696127001229	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
696127001230	IHF dimer interface [polypeptide binding]; other site
696127001231	IHF - DNA interface [nucleotide binding]; other site
696127001232	TolQ protein; Region: tolQ; TIGR02796
696127001233	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
696127001234	TolR protein; Region: tolR; TIGR02801
696127001235	Gram-negative bacterial tonB protein; Region: TonB; cl10048
696127001236	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
696127001237	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
696127001238	Transporter associated domain; Region: CorC_HlyC; smart01091
696127001239	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
696127001240	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
696127001241	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
696127001242	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
696127001243	IHF dimer interface [polypeptide binding]; other site
696127001244	IHF - DNA interface [nucleotide binding]; other site
696127001245	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
696127001246	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
696127001247	active site
696127001248	Queuosine biosynthesis protein; Region: Queuosine_synth; cl00523
696127001249	Queuosine biosynthesis protein; Region: Queuosine_synth; cl00523
696127001250	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
696127001251	putative active site [active]
696127001252	Ap4A binding site [chemical binding]; other site
696127001253	nudix motif; other site
696127001254	putative metal binding site [ion binding]; other site
696127001255	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
696127001256	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
696127001257	dimer interface [polypeptide binding]; other site
696127001258	ssDNA binding site [nucleotide binding]; other site
696127001259	tetramer (dimer of dimers) interface [polypeptide binding]; other site
696127001260	ribosomal protein L31; Region: L31; TIGR00105
696127001261	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
696127001262	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
696127001263	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
696127001264	Transglycosylase; Region: Transgly; pfam00912
696127001265	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
696127001266	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13254
696127001267	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
696127001268	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
696127001269	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
696127001270	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
696127001271	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
696127001272	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696127001273	Walker A/P-loop; other site
696127001274	ATP binding site [chemical binding]; other site
696127001275	Q-loop/lid; other site
696127001276	ABC transporter signature motif; other site
696127001277	Walker B; other site
696127001278	D-loop; other site
696127001279	H-loop/switch region; other site
696127001280	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696127001281	dimer interface [polypeptide binding]; other site
696127001282	conserved gate region; other site
696127001283	putative PBP binding loops; other site
696127001284	ABC-ATPase subunit interface; other site
696127001285	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
696127001286	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696127001287	intermolecular recognition site; other site
696127001288	active site
696127001289	dimerization interface [polypeptide binding]; other site
696127001290	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696127001291	DNA binding site [nucleotide binding]
696127001292	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
696127001293	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
696127001294	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
696127001295	histidinol-phosphate aminotransferase; Provisional; Region: PRK04635
696127001296	elongation factor Tu; Reviewed; Region: PRK00049
696127001297	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
696127001298	G1 box; other site
696127001299	GEF interaction site [polypeptide binding]; other site
696127001300	GTP/Mg2+ binding site [chemical binding]; other site
696127001301	Switch I region; other site
696127001302	G2 box; other site
696127001303	G3 box; other site
696127001304	Switch II region; other site
696127001305	G4 box; other site
696127001306	G5 box; other site
696127001307	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
696127001308	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
696127001309	Antibiotic Binding Site [chemical binding]; other site
696127001310	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
696127001311	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
696127001312	23S rRNA binding site [nucleotide binding]; other site
696127001313	L21 binding site [polypeptide binding]; other site
696127001314	L13 binding site [polypeptide binding]; other site
696127001315	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
696127001316	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
696127001317	IHF - DNA interface [nucleotide binding]; other site
696127001318	IHF dimer interface [polypeptide binding]; other site
696127001319	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
696127001320	ssDNA binding site; other site
696127001321	ATP-dependent DNA helicase RecG; Region: recG; TIGR00643
696127001322	generic binding surface II; other site
696127001323	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696127001324	ATP binding site [chemical binding]; other site
696127001325	putative Mg++ binding site [ion binding]; other site
696127001326	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696127001327	nucleotide binding region [chemical binding]; other site
696127001328	ATP-binding site [chemical binding]; other site
696127001329	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
696127001330	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
696127001331	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
696127001332	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
696127001333	homodimer interface [polypeptide binding]; other site
696127001334	NADP binding site [chemical binding]; other site
696127001335	substrate binding site [chemical binding]; other site
696127001336	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
696127001337	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
696127001338	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696127001339	Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208
696127001340	active site
696127001341	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696127001342	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696127001343	putative substrate translocation pore; other site
696127001344	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001345	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001346	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001347	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
696127001348	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
696127001349	RNA binding site [nucleotide binding]; other site
696127001350	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
696127001351	RNA binding site [nucleotide binding]; other site
696127001352	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
696127001353	RNA binding site [nucleotide binding]; other site
696127001354	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
696127001355	RNA binding site [nucleotide binding]; other site
696127001356	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
696127001357	RNA binding site [nucleotide binding]; other site
696127001358	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
696127001359	RNA binding site [nucleotide binding]; other site
696127001360	cytidylate kinase; Provisional; Region: cmk; PRK00023
696127001361	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
696127001362	CMP-binding site; other site
696127001363	The sites determining sugar specificity; other site
696127001364	Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770
696127001365	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
696127001366	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
696127001367	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
696127001368	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
696127001369	carboxyltransferase (CT) interaction site; other site
696127001370	biotinylation site [posttranslational modification]; other site
696127001371	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696127001372	putative substrate translocation pore; other site
696127001373	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696127001374	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
696127001375	aromatic amino acid transport protein; Region: araaP; TIGR00837
696127001376	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
696127001377	SurA N-terminal domain; Region: SurA_N; pfam09312
696127001378	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
696127001379	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
696127001380	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
696127001381	Organic solvent tolerance protein; Region: OstA_C; pfam04453
696127001382	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
696127001383	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
696127001384	homodimer interface [polypeptide binding]; other site
696127001385	substrate-cofactor binding pocket; other site
696127001386	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696127001387	catalytic residue [active]
696127001388	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
696127001389	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696127001390	S-adenosylmethionine binding site [chemical binding]; other site
696127001391	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
696127001392	MutS domain I; Region: MutS_I; pfam01624
696127001393	MutS domain II; Region: MutS_II; pfam05188
696127001394	MutS domain III; Region: MutS_III; pfam05192
696127001395	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
696127001396	Walker A/P-loop; other site
696127001397	ATP binding site [chemical binding]; other site
696127001398	Q-loop/lid; other site
696127001399	ABC transporter signature motif; other site
696127001400	Walker B; other site
696127001401	D-loop; other site
696127001402	H-loop/switch region; other site
696127001403	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
696127001404	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; cl00588
696127001405	Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170
696127001406	PLD-like domain; Region: PLDc_2; pfam13091
696127001407	putative active site [active]
696127001408	catalytic site [active]
696127001409	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
696127001410	HlyD family secretion protein; Region: HlyD_3; pfam13437
696127001411	ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only]; Region: ArpD; COG4618
696127001412	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
696127001413	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696127001414	Walker A/P-loop; other site
696127001415	ATP binding site [chemical binding]; other site
696127001416	Q-loop/lid; other site
696127001417	ABC transporter signature motif; other site
696127001418	Walker B; other site
696127001419	D-loop; other site
696127001420	H-loop/switch region; other site
696127001421	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
696127001422	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
696127001423	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001424	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001425	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
696127001426	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
696127001427	domain interfaces; other site
696127001428	active site
696127001429	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
696127001430	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
696127001431	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
696127001432	Zn2+ binding site [ion binding]; other site
696127001433	Mg2+ binding site [ion binding]; other site
696127001434	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
696127001435	synthetase active site [active]
696127001436	NTP binding site [chemical binding]; other site
696127001437	metal binding site [ion binding]; metal-binding site
696127001438	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
696127001439	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001440	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
696127001441	active site
696127001442	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
696127001443	EamA-like transporter family; Region: EamA; pfam00892
696127001444	Predicted esterase [General function prediction only]; Region: COG0400
696127001445	putative hydrolase; Provisional; Region: PRK11460
696127001446	cell division protein FtsW; Region: ftsW; TIGR02614
696127001447	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
696127001448	Tetratricopeptide repeat; Region: TPR_12; pfam13424
696127001449	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
696127001450	binding surface
696127001451	TPR motif; other site
696127001452	Tetratricopeptide repeat; Region: TPR_12; pfam13424
696127001453	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
696127001454	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
696127001455	glutaminase active site [active]
696127001456	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
696127001457	dimer interface [polypeptide binding]; other site
696127001458	active site
696127001459	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
696127001460	dimer interface [polypeptide binding]; other site
696127001461	active site
696127001462	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
696127001463	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001464	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
696127001465	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
696127001466	NADP binding site [chemical binding]; other site
696127001467	dimer interface [polypeptide binding]; other site
696127001468	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
696127001469	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
696127001470	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
696127001471	Domain of unknown function DUF21; Region: DUF21; pfam01595
696127001472	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
696127001473	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
696127001474	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
696127001475	Transporter associated domain; Region: CorC_HlyC; smart01091
696127001476	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
696127001477	active site residue [active]
696127001478	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
696127001479	dimer interface [polypeptide binding]; other site
696127001480	substrate binding site [chemical binding]; other site
696127001481	metal binding sites [ion binding]; metal-binding site
696127001482	DNA polymerase I; Provisional; Region: PRK05755
696127001483	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
696127001484	active site
696127001485	metal binding site 1 [ion binding]; metal-binding site
696127001486	putative 5' ssDNA interaction site; other site
696127001487	metal binding site 3; metal-binding site
696127001488	metal binding site 2 [ion binding]; metal-binding site
696127001489	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
696127001490	putative DNA binding site [nucleotide binding]; other site
696127001491	putative metal binding site [ion binding]; other site
696127001492	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
696127001493	active site
696127001494	substrate binding site [chemical binding]; other site
696127001495	catalytic site [active]
696127001496	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
696127001497	active site
696127001498	DNA binding site [nucleotide binding]
696127001499	catalytic site [active]
696127001500	Bacterial NAD-glutamate dehydrogenase; Region: Bac_GDH; pfam05088
696127001501	DNA polymerase III chi subunit, HolC; Region: DNA_pol3_chi; cl01106
696127001502	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
696127001503	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
696127001504	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
696127001505	Predicted secreted (periplasmic) protein [Function unknown]; Region: COG5462
696127001506	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
696127001507	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696127001508	S-adenosylmethionine binding site [chemical binding]; other site
696127001509	cell division protein MraZ; Reviewed; Region: PRK00326
696127001510	MraZ protein; Region: MraZ; pfam02381
696127001511	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
696127001512	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
696127001513	Zn2+ binding site [ion binding]; other site
696127001514	Mg2+ binding site [ion binding]; other site
696127001515	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
696127001516	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
696127001517	ETC complex I subunit conserved region; Region: ETC_C1_NDUFA4; pfam04800
696127001518	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
696127001519	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
696127001520	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
696127001521	putative active site [active]
696127001522	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
696127001523	ribosome recycling factor; Reviewed; Region: frr; PRK00083
696127001524	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
696127001525	hinge region; other site
696127001526	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
696127001527	putative nucleotide binding site [chemical binding]; other site
696127001528	uridine monophosphate binding site [chemical binding]; other site
696127001529	homohexameric interface [polypeptide binding]; other site
696127001530	elongation factor Ts; Provisional; Region: tsf; PRK09377
696127001531	UBA/TS-N domain; Region: UBA; pfam00627
696127001532	Elongation factor TS; Region: EF_TS; pfam00889
696127001533	Elongation factor TS; Region: EF_TS; pfam00889
696127001534	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
696127001535	rRNA interaction site [nucleotide binding]; other site
696127001536	S8 interaction site; other site
696127001537	putative laminin-1 binding site; other site
696127001538	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
696127001539	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
696127001540	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms]; Region: NtrY; COG5000
696127001541	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696127001542	dimerization interface [polypeptide binding]; other site
696127001543	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696127001544	dimer interface [polypeptide binding]; other site
696127001545	phosphorylation site [posttranslational modification]
696127001546	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696127001547	ATP binding site [chemical binding]; other site
696127001548	G-X-G motif; other site
696127001549	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
696127001550	EamA-like transporter family; Region: EamA; pfam00892
696127001551	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
696127001552	EamA-like transporter family; Region: EamA; pfam00892
696127001553	EamA-like transporter family; Region: EamA; pfam00892
696127001554	peptide chain release factor 1; Validated; Region: prfA; PRK00591
696127001555	This domain is found in peptide chain release factors; Region: PCRF; smart00937
696127001556	RF-1 domain; Region: RF-1; pfam00472
696127001557	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
696127001558	Family description; Region: VCBS; pfam13517
696127001559	Family description; Region: VCBS; pfam13517
696127001560	Family description; Region: VCBS; pfam13517
696127001561	isocitrate dehydrogenase; Validated; Region: PRK09222
696127001562	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
696127001563	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
696127001564	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
696127001565	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
696127001566	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
696127001567	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
696127001568	SmpB-tmRNA interface; other site
696127001569	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
696127001570	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
696127001571	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
696127001572	Uncharacterized conserved protein [Function unknown]; Region: COG1434
696127001573	putative active site [active]
696127001574	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
696127001575	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
696127001576	active site
696127001577	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
696127001578	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
696127001579	GatB domain; Region: GatB_Yqey; smart00845
696127001580	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
696127001581	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
696127001582	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
696127001583	Disulfide bond formation protein DsbB; Region: DsbB; pfam02600
696127001584	Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042
696127001585	diiron binding motif [ion binding]; other site
696127001586	Cytochrome c2 [Energy production and conversion]; Region: COG3474
696127001587	Family description; Region: VCBS; pfam13517
696127001588	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
696127001589	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
696127001590	TPP-binding site [chemical binding]; other site
696127001591	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
696127001592	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
696127001593	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
696127001594	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
696127001595	Eukaryotic Glutathione Synthetase (eu-GS); catalyses the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner. Belongs to the ATP-grasp superfamily; Region: eu-GS; cl00170
696127001596	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696127001597	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
696127001598	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001599	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001600	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
696127001601	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
696127001602	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696127001603	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
696127001604	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
696127001605	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; pfam04610
696127001606	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; pfam04610
696127001607	CTP synthetase; Validated; Region: pyrG; PRK05380
696127001608	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
696127001609	Catalytic site [active]
696127001610	active site
696127001611	UTP binding site [chemical binding]; other site
696127001612	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
696127001613	active site
696127001614	putative oxyanion hole; other site
696127001615	catalytic triad [active]
696127001616	protein translocase, SecG subunit; Region: secG; TIGR00810
696127001617	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
696127001618	Septum formation initiator; Region: DivIC; pfam04977
696127001619	TrbC/VIRB2 family; Region: TrbC; pfam04956
696127001620	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
696127001621	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
696127001622	substrate binding pocket [chemical binding]; other site
696127001623	chain length determination region; other site
696127001624	substrate-Mg2+ binding site; other site
696127001625	catalytic residues [active]
696127001626	aspartate-rich region 1; other site
696127001627	active site lid residues [active]
696127001628	aspartate-rich region 2; other site
696127001629	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001630	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001631	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001632	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
696127001633	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
696127001634	HIGH motif; other site
696127001635	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
696127001636	active site
696127001637	KMSKS motif; other site
696127001638	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
696127001639	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
696127001640	TPP-binding site; other site
696127001641	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
696127001642	PYR/PP interface [polypeptide binding]; other site
696127001643	dimer interface [polypeptide binding]; other site
696127001644	TPP binding site [chemical binding]; other site
696127001645	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
696127001646	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
696127001647	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
696127001648	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
696127001649	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
696127001650	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
696127001651	Ankyrin repeat; Region: Ank; pfam00023
696127001652	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
696127001653	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
696127001654	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
696127001655	HD domain; Region: HD_4; pfam13328
696127001656	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
696127001657	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
696127001658	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
696127001659	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
696127001660	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
696127001661	DNA binding residues [nucleotide binding]
696127001662	Flagellar basal body-associated protein FliL; Region: FliL; cl00681
696127001663	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07718
696127001664	Flagellar motor switch protein FliM; Region: FliM; pfam02154
696127001665	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
696127001666	Uncharacterized conserved protein [Function unknown]; Region: COG3334
696127001667	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
696127001668	FAD binding domain; Region: FAD_binding_4; pfam01565
696127001669	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
696127001670	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
696127001671	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14315
696127001672	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
696127001673	active site
696127001674	substrate binding site [chemical binding]; other site
696127001675	metal binding site [ion binding]; metal-binding site
696127001676	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
696127001677	active site
696127001678	tetramer interface; other site
696127001679	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
696127001680	Part of AAA domain; Region: AAA_19; pfam13245
696127001681	Family description; Region: UvrD_C_2; pfam13538
696127001682	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
696127001683	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
696127001684	catalytic residue [active]
696127001685	putative FPP diphosphate  binding site; other site
696127001686	putative FPP binding hydrophobic cleft; other site
696127001687	dimer interface [polypeptide binding]; other site
696127001688	putative IPP diphosphate binding site; other site
696127001689	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
696127001690	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
696127001691	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
696127001692	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
696127001693	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
696127001694	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
696127001695	FG-GAP repeat; Region: FG-GAP; cl15299
696127001696	translocation protein TolB; Provisional; Region: tolB; PRK05137
696127001697	TolB amino-terminal domain; Region: TolB_N; pfam04052
696127001698	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
696127001699	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
696127001700	Protein of unknown function (DUF2497); Region: DUF2497; pfam10691
696127001701	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
696127001702	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
696127001703	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
696127001704	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
696127001705	IHF - DNA interface [nucleotide binding]; other site
696127001706	IHF dimer interface [polypeptide binding]; other site
696127001707	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
696127001708	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
696127001709	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cl02529
696127001710	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
696127001711	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
696127001712	dimer interface [polypeptide binding]; other site
696127001713	active site
696127001714	ATPase MipZ; Region: MipZ; pfam09140
696127001715	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
696127001716	P-loop; other site
696127001717	Magnesium ion binding site [ion binding]; other site
696127001718	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
696127001719	Magnesium ion binding site [ion binding]; other site
696127001720	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
696127001721	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
696127001722	dimer interface [polypeptide binding]; other site
696127001723	motif 1; other site
696127001724	active site
696127001725	motif 2; other site
696127001726	motif 3; other site
696127001727	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
696127001728	anticodon binding site; other site
696127001729	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
696127001730	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
696127001731	substrate-cofactor binding pocket; other site
696127001732	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696127001733	catalytic residue [active]
696127001734	HflC protein; Region: hflC; TIGR01932
696127001735	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
696127001736	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
696127001737	HflK protein; Region: hflK; TIGR01933
696127001738	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
696127001739	trigger factor; Provisional; Region: tig; PRK01490
696127001740	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
696127001741	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
696127001742	Clp protease; Region: CLP_protease; pfam00574
696127001743	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
696127001744	oligomer interface [polypeptide binding]; other site
696127001745	active site residues [active]
696127001746	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
696127001747	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
696127001748	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696127001749	Walker A motif; other site
696127001750	ATP binding site [chemical binding]; other site
696127001751	Walker B motif; other site
696127001752	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
696127001753	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
696127001754	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696127001755	putative substrate translocation pore; other site
696127001756	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
696127001757	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
696127001758	active site
696127001759	HIGH motif; other site
696127001760	nucleotide binding site [chemical binding]; other site
696127001761	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
696127001762	KMSKS motif; other site
696127001763	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
696127001764	tRNA binding surface [nucleotide binding]; other site
696127001765	anticodon binding site; other site
696127001766	GTP-binding protein LepA; Provisional; Region: PRK05433
696127001767	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
696127001768	G1 box; other site
696127001769	putative GEF interaction site [polypeptide binding]; other site
696127001770	GTP/Mg2+ binding site [chemical binding]; other site
696127001771	Switch I region; other site
696127001772	G2 box; other site
696127001773	G3 box; other site
696127001774	Switch II region; other site
696127001775	G4 box; other site
696127001776	G5 box; other site
696127001777	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
696127001778	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
696127001779	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
696127001780	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
696127001781	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; pfam04610
696127001782	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; cl01503
696127001783	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001784	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
696127001785	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
696127001786	putative acyl-acceptor binding pocket; other site
696127001787	Tetratricopeptide repeat; Region: TPR_12; pfam13424
696127001788	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
696127001789	binding surface
696127001790	TPR motif; other site
696127001791	Tetratricopeptide repeat; Region: TPR_12; pfam13424
696127001792	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001793	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696127001794	Predicted methyltransferases [General function prediction only]; Region: COG0313
696127001795	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
696127001796	putative SAM binding site [chemical binding]; other site
696127001797	putative homodimer interface [polypeptide binding]; other site
696127001798	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
696127001799	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
696127001800	prolyl-tRNA synthetase; Provisional; Region: PRK12325
696127001801	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
696127001802	dimer interface [polypeptide binding]; other site
696127001803	motif 1; other site
696127001804	active site
696127001805	motif 2; other site
696127001806	motif 3; other site
696127001807	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
696127001808	anticodon binding site; other site
696127001809	UGMP family protein; Validated; Region: PRK09604
696127001810	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
696127001811	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
696127001812	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
696127001813	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
696127001814	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
696127001815	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
696127001816	active site
696127001817	DNA binding site [nucleotide binding]
696127001818	Int/Topo IB signature motif; other site
696127001819	Uncharacterized protein family (UPF0104); Region: UPF0104; cl04219
696127001820	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001821	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
696127001822	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
696127001823	active site
696127001824	(T/H)XGH motif; other site
696127001825	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
696127001826	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
696127001827	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
696127001828	active site
696127001829	ferrochelatase; Reviewed; Region: hemH; PRK00035
696127001830	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
696127001831	C-terminal domain interface [polypeptide binding]; other site
696127001832	active site
696127001833	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
696127001834	active site
696127001835	N-terminal domain interface [polypeptide binding]; other site
696127001836	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14353
696127001837	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
696127001838	Substrate binding site; other site
696127001839	Mg++ binding site; other site
696127001840	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
696127001841	active site
696127001842	substrate binding site [chemical binding]; other site
696127001843	CoA binding site [chemical binding]; other site
696127001844	Phage capsid family; Region: Phage_capsid; pfam05065
696127001845	30S ribosomal protein S12; Validated; Region: rpsL; PRK05163
696127001846	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
696127001847	30S ribosomal protein S7; Validated; Region: PRK05302
696127001848	elongation factor G; Reviewed; Region: PRK00007
696127001849	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
696127001850	G1 box; other site
696127001851	putative GEF interaction site [polypeptide binding]; other site
696127001852	GTP/Mg2+ binding site [chemical binding]; other site
696127001853	Switch I region; other site
696127001854	G2 box; other site
696127001855	G3 box; other site
696127001856	Switch II region; other site
696127001857	G4 box; other site
696127001858	G5 box; other site
696127001859	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
696127001860	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
696127001861	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
696127001862	Dolichol kinase [Lipid metabolism]; Region: SEC59; COG0170
696127001863	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
696127001864	motif 1; other site
696127001865	dimer interface [polypeptide binding]; other site
696127001866	active site
696127001867	motif 2; other site
696127001868	motif 3; other site
696127001869	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001870	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001871	phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154
696127001872	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696127001873	active site
696127001874	phosphorylation site [posttranslational modification]
696127001875	intermolecular recognition site; other site
696127001876	dimerization interface [polypeptide binding]; other site
696127001877	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696127001878	DNA binding site [nucleotide binding]
696127001879	fumarate hydratase; Reviewed; Region: fumC; PRK00485
696127001880	Class II fumarases; Region: Fumarase_classII; cd01362
696127001881	active site
696127001882	tetramer interface [polypeptide binding]; other site
696127001883	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
696127001884	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
696127001885	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
696127001886	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
696127001887	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
696127001888	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
696127001889	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696127001890	S-adenosylmethionine binding site [chemical binding]; other site
696127001891	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
696127001892	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
696127001893	catalytic site [active]
696127001894	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696127001895	metabolite-proton symporter; Region: 2A0106; TIGR00883
696127001896	putative substrate translocation pore; other site
696127001897	S-adenosyl-l-methionine hydroxide adenosyltransferase; Region: SAM_adeno_trans; cl17774
696127001898	signal recognition particle protein; Provisional; Region: PRK10867
696127001899	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
696127001900	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
696127001901	P loop; other site
696127001902	GTP binding site [chemical binding]; other site
696127001903	Signal peptide binding domain; Region: SRP_SPB; pfam02978
696127001904	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
696127001905	SmpA / OmlA family; Region: SmpA_OmlA; cl17115
696127001906	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
696127001907	DNA binding site [nucleotide binding]
696127001908	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
696127001909	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
696127001910	dimer interface [polypeptide binding]; other site
696127001911	decamer (pentamer of dimers) interface [polypeptide binding]; other site
696127001912	catalytic triad [active]
696127001913	peroxidatic and resolving cysteines [active]
696127001914	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
696127001915	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
696127001916	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696127001917	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001918	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
696127001919	catalytic motif [active]
696127001920	Zn binding site [ion binding]; other site
696127001921	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
696127001922	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
696127001923	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696127001924	motif II; other site
696127001925	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
696127001926	metal-binding site [ion binding]
696127001927	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
696127001928	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
696127001929	Soluble P-type ATPase [General function prediction only]; Region: COG4087
696127001930	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
696127001931	Domain of unknown function (DUF3470); Region: DUF3470; pfam11953
696127001932	lumazine synthase and riboflavin synthase; involved in the riboflavin (vitamin B2) biosynthetic pathway; Region: Lumazine_synthase-like; cl00317
696127001933	homopentamer interface [polypeptide binding]; other site
696127001934	active site
696127001935	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
696127001936	putative RNA binding site [nucleotide binding]; other site
696127001937	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001938	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127001939	putative hydrolase; Provisional; Region: PRK02113
696127001940	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
696127001941	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
696127001942	active site
696127001943	catalytic residues [active]
696127001944	metal binding site [ion binding]; metal-binding site
696127001945	aspartate aminotransferase; Provisional; Region: PRK05764
696127001946	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
696127001947	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696127001948	homodimer interface [polypeptide binding]; other site
696127001949	catalytic residue [active]
696127001950	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
696127001951	Na binding site [ion binding]; other site
696127001952	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
696127001953	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696127001954	ATP binding site [chemical binding]; other site
696127001955	Mg2+ binding site [ion binding]; other site
696127001956	G-X-G motif; other site
696127001957	CoA binding domain; Region: CoA_binding; smart00881
696127001958	CoA-ligase; Region: Ligase_CoA; pfam00549
696127001959	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
696127001960	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
696127001961	CoA-ligase; Region: Ligase_CoA; pfam00549
696127001962	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
696127001963	nucleotide binding site/active site [active]
696127001964	HIT family signature motif; other site
696127001965	catalytic residue [active]
696127001966	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
696127001967	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
696127001968	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696127001969	Walker A motif; other site
696127001970	ATP binding site [chemical binding]; other site
696127001971	Walker B motif; other site
696127001972	arginine finger; other site
696127001973	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
696127001974	hypothetical protein; Validated; Region: PRK00153
696127001975	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
696127001976	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
696127001977	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cl00700
696127001978	dimer interface [polypeptide binding]; other site
696127001979	catalytic triad [active]
696127001980	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
696127001981	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696127001982	S-adenosylmethionine binding site [chemical binding]; other site
696127001983	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
696127001984	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
696127001985	amidase catalytic site [active]
696127001986	Zn binding residues [ion binding]; other site
696127001987	substrate binding site [chemical binding]; other site
696127001988	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
696127001989	Preprotein translocase subunit; Region: YajC; pfam02699
696127001990	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
696127001991	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
696127001992	catalytic loop [active]
696127001993	iron binding site [ion binding]; other site
696127001994	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
696127001995	NADH dehydrogenase subunit B; Validated; Region: PRK06411
696127001996	Cytochrome C1 family; Region: Cytochrom_C1; pfam02167
696127001997	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
696127001998	ABC1 family; Region: ABC1; pfam03109
696127001999	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
696127002000	active site
696127002001	ATP binding site [chemical binding]; other site
696127002002	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
696127002003	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
696127002004	dimer interface [polypeptide binding]; other site
696127002005	active site
696127002006	citrylCoA binding site [chemical binding]; other site
696127002007	NADH binding [chemical binding]; other site
696127002008	cationic pore residues; other site
696127002009	oxalacetate/citrate binding site [chemical binding]; other site
696127002010	coenzyme A binding site [chemical binding]; other site
696127002011	catalytic triad [active]
696127002012	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002013	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
696127002014	VirB7 interaction site; other site
696127002015	VirB8 protein; Region: VirB8; cl01500
696127002016	Uncharacterized conserved protein [Function unknown]; Region: COG1565
696127002017	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
696127002018	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
696127002019	Membrane transport protein; Region: Mem_trans; cl09117
696127002020	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
696127002021	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
696127002022	active site
696127002023	NTP binding site [chemical binding]; other site
696127002024	metal binding triad [ion binding]; metal-binding site
696127002025	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
696127002026	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
696127002027	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
696127002028	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002029	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002030	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
696127002031	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
696127002032	23S rRNA interface [nucleotide binding]; other site
696127002033	L3 interface [polypeptide binding]; other site
696127002034	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002035	Stringent starvation protein B; Region: SspB; pfam04386
696127002036	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
696127002037	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
696127002038	putative active site [active]
696127002039	substrate binding site [chemical binding]; other site
696127002040	putative cosubstrate binding site; other site
696127002041	catalytic site [active]
696127002042	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
696127002043	substrate binding site [chemical binding]; other site
696127002044	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
696127002045	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
696127002046	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
696127002047	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
696127002048	DHH family; Region: DHH; pfam01368
696127002049	DHHA1 domain; Region: DHHA1; pfam02272
696127002050	GrpE; Region: GrpE; pfam01025
696127002051	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
696127002052	dimer interface [polypeptide binding]; other site
696127002053	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
696127002054	malate dehydrogenase; Reviewed; Region: PRK06223
696127002055	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
696127002056	NAD(P) binding site [chemical binding]; other site
696127002057	dimer interface [polypeptide binding]; other site
696127002058	tetramer (dimer of dimers) interface [polypeptide binding]; other site
696127002059	substrate binding site [chemical binding]; other site
696127002060	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002061	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
696127002062	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
696127002063	catalytic triad [active]
696127002064	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
696127002065	dihydropteroate synthase; Region: DHPS; TIGR01496
696127002066	substrate binding pocket [chemical binding]; other site
696127002067	dimer interface [polypeptide binding]; other site
696127002068	inhibitor binding site; inhibition site
696127002069	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cl00233
696127002070	catalytic center binding site [active]
696127002071	ATP binding site [chemical binding]; other site
696127002072	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
696127002073	aspartate kinase; Reviewed; Region: PRK06635
696127002074	AAK_AK-DapG-like: Amino Acid Kinase Superfamily (AAK), AK-DapG-like; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the diaminopimelate-sensitive aspartokinase isoenzyme AKI (DapG), a monofunctional enzymes found in Bacilli; Region: AAK_AK-DapG-like; cd04246
696127002075	putative catalytic residues [active]
696127002076	putative nucleotide binding site [chemical binding]; other site
696127002077	putative aspartate binding site [chemical binding]; other site
696127002078	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
696127002079	Predicted permeases [General function prediction only]; Region: COG0795
696127002080	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
696127002081	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
696127002082	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
696127002083	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
696127002084	generic binding surface II; other site
696127002085	generic binding surface I; other site
696127002086	YceG-like family; Region: YceG; pfam02618
696127002087	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
696127002088	dimerization interface [polypeptide binding]; other site
696127002089	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002090	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
696127002091	Clp amino terminal domain; Region: Clp_N; pfam02861
696127002092	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696127002093	Walker A motif; other site
696127002094	ATP binding site [chemical binding]; other site
696127002095	Walker B motif; other site
696127002096	arginine finger; other site
696127002097	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696127002098	Walker A motif; other site
696127002099	ATP binding site [chemical binding]; other site
696127002100	Walker B motif; other site
696127002101	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
696127002102	TspO/MBR family; Region: TspO_MBR; cl01379
696127002103	Integral membrane protein TerC family; Region: TerC; cl10468
696127002104	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
696127002105	Malic enzyme, N-terminal domain; Region: malic; pfam00390
696127002106	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
696127002107	putative NAD(P) binding site [chemical binding]; other site
696127002108	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
696127002109	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
696127002110	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
696127002111	active site
696127002112	substrate binding site [chemical binding]; other site
696127002113	metal binding site [ion binding]; metal-binding site
696127002114	glutamyl-tRNA synthetase; Provisional; Region: PRK12558
696127002115	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
696127002116	active site
696127002117	HIGH motif; other site
696127002118	nucleotide binding site [chemical binding]; other site
696127002119	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
696127002120	active site
696127002121	KMSKS motif; other site
696127002122	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
696127002123	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
696127002124	metal binding site [ion binding]; metal-binding site
696127002125	dimer interface [polypeptide binding]; other site
696127002126	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
696127002127	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
696127002128	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
696127002129	Predicted flavoprotein [General function prediction only]; Region: COG0431
696127002130	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
696127002131	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
696127002132	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
696127002133	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
696127002134	ligand binding site [chemical binding]; other site
696127002135	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
696127002136	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
696127002137	Maf-like protein; Region: Maf; pfam02545
696127002138	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
696127002139	active site
696127002140	dimer interface [polypeptide binding]; other site
696127002141	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
696127002142	rRNA binding site [nucleotide binding]; other site
696127002143	predicted 30S ribosome binding site; other site
696127002144	Protein of unknown function (DUF1009); Region: DUF1009; pfam06230
696127002145	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
696127002146	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
696127002147	active site
696127002148	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
696127002149	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
696127002150	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
696127002151	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
696127002152	protein binding site [polypeptide binding]; other site
696127002153	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
696127002154	protein binding site [polypeptide binding]; other site
696127002155	ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204
696127002156	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
696127002157	ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; Region: ABC_MTABC3_MDL1_MDL2; cd03249
696127002158	Walker A/P-loop; other site
696127002159	ATP binding site [chemical binding]; other site
696127002160	Q-loop/lid; other site
696127002161	ABC transporter signature motif; other site
696127002162	Walker B; other site
696127002163	D-loop; other site
696127002164	H-loop/switch region; other site
696127002165	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
696127002166	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
696127002167	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
696127002168	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
696127002169	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
696127002170	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
696127002171	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
696127002172	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
696127002173	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
696127002174	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
696127002175	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
696127002176	active site
696127002177	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
696127002178	Protein of unknown function (DUF541); Region: SIMPL; cl01077
696127002179	Protein of unknown function (DUF541); Region: SIMPL; cl01077
696127002180	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
696127002181	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
696127002182	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
696127002183	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK09078
696127002184	L-aspartate oxidase; Provisional; Region: PRK06175
696127002185	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
696127002186	Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, transmembrane subunits; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol, while QFR catalyzes the reverse reaction. SQR; Region: SQR_QFR_TM; cl00881
696127002187	Iron-sulfur protein interface; other site
696127002188	proximal heme binding site [chemical binding]; other site
696127002189	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
696127002190	proximal quinone binding site [chemical binding]; other site
696127002191	SdhD (CybS) interface [polypeptide binding]; other site
696127002192	proximal heme binding site [chemical binding]; other site
696127002193	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167
696127002194	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
696127002195	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
696127002196	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
696127002197	HIGH motif; other site
696127002198	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
696127002199	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
696127002200	active site
696127002201	KMSKS motif; other site
696127002202	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
696127002203	tRNA binding surface [nucleotide binding]; other site
696127002204	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
696127002205	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
696127002206	TPR motif; other site
696127002207	binding surface
696127002208	Dihydroneopterin aldolase; Region: FolB; smart00905
696127002209	active site
696127002210	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696127002211	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
696127002212	substrate binding pocket [chemical binding]; other site
696127002213	membrane-bound complex binding site; other site
696127002214	hinge residues; other site
696127002215	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
696127002216	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
696127002217	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
696127002218	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
696127002219	Ligand binding site; other site
696127002220	Putative Catalytic site; other site
696127002221	DXD motif; other site
696127002222	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
696127002223	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
696127002224	CoA-binding site [chemical binding]; other site
696127002225	ATP-binding [chemical binding]; other site
696127002226	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
696127002227	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
696127002228	active site
696127002229	catalytic site [active]
696127002230	substrate binding site [chemical binding]; other site
696127002231	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
696127002232	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
696127002233	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
696127002234	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
696127002235	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
696127002236	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002237	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
696127002238	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
696127002239	HIGH motif; other site
696127002240	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
696127002241	active site
696127002242	KMSKS motif; other site
696127002243	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
696127002244	tRNA binding surface [nucleotide binding]; other site
696127002245	anticodon binding site; other site
696127002246	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
696127002247	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
696127002248	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
696127002249	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
696127002250	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
696127002251	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
696127002252	DNA binding residues [nucleotide binding]
696127002253	DNA primase; Validated; Region: dnaG; PRK05667
696127002254	CHC2 zinc finger; Region: zf-CHC2; pfam01807
696127002255	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
696127002256	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
696127002257	active site
696127002258	metal binding site [ion binding]; metal-binding site
696127002259	interdomain interaction site; other site
696127002260	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
696127002261	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
696127002262	active site
696127002263	DNA binding site [nucleotide binding]
696127002264	Int/Topo IB signature motif; other site
696127002265	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
696127002266	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
696127002267	catalytic site [active]
696127002268	putative active site [active]
696127002269	putative substrate binding site [chemical binding]; other site
696127002270	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
696127002271	putative active site [active]
696127002272	catalytic residue [active]
696127002273	GTP-binding protein YchF; Reviewed; Region: PRK09601
696127002274	YchF GTPase; Region: YchF; cd01900
696127002275	G1 box; other site
696127002276	GTP/Mg2+ binding site [chemical binding]; other site
696127002277	Switch I region; other site
696127002278	G2 box; other site
696127002279	Switch II region; other site
696127002280	G3 box; other site
696127002281	G4 box; other site
696127002282	G5 box; other site
696127002283	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
696127002284	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
696127002285	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
696127002286	dimer interface [polypeptide binding]; other site
696127002287	anticodon binding site; other site
696127002288	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
696127002289	homodimer interface [polypeptide binding]; other site
696127002290	motif 1; other site
696127002291	active site
696127002292	motif 2; other site
696127002293	GAD domain; Region: GAD; pfam02938
696127002294	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
696127002295	active site
696127002296	motif 3; other site
696127002297	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
696127002298	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
696127002299	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
696127002300	active site
696127002301	dimerization interface [polypeptide binding]; other site
696127002302	histidinol-phosphate aminotransferase; Provisional; Region: PRK04635
696127002303	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
696127002304	G1 box; other site
696127002305	GTP/Mg2+ binding site [chemical binding]; other site
696127002306	Switch I region; other site
696127002307	G2 box; other site
696127002308	G3 box; other site
696127002309	Switch II region; other site
696127002310	G4 box; other site
696127002311	G5 box; other site
696127002312	NADH dehydrogenase I subunit F; Provisional; Region: PRK13596
696127002313	SLBB domain; Region: SLBB; pfam10531
696127002314	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
696127002315	Transglycosylase; Region: Transgly; pfam00912
696127002316	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
696127002317	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
696127002318	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002319	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002320	flagellar hook-basal body protein; Region: FlgEFG_subfam; TIGR03506
696127002321	glutamine synthetase, type III; Region: gln_synth_III; TIGR03105
696127002322	excinuclease ABC subunit B; Provisional; Region: PRK05298
696127002323	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696127002324	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696127002325	nucleotide binding region [chemical binding]; other site
696127002326	ATP-binding site [chemical binding]; other site
696127002327	Ultra-violet resistance protein B; Region: UvrB; pfam12344
696127002328	UvrB/uvrC motif; Region: UVR; pfam02151
696127002329	DNA topoisomerase I; Validated; Region: PRK06599
696127002330	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
696127002331	active site
696127002332	interdomain interaction site; other site
696127002333	putative metal-binding site [ion binding]; other site
696127002334	nucleotide binding site [chemical binding]; other site
696127002335	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
696127002336	domain I; other site
696127002337	DNA binding groove [nucleotide binding]
696127002338	phosphate binding site [ion binding]; other site
696127002339	domain II; other site
696127002340	domain III; other site
696127002341	nucleotide binding site [chemical binding]; other site
696127002342	catalytic site [active]
696127002343	domain IV; other site
696127002344	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
696127002345	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
696127002346	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
696127002347	nucleoside/Zn binding site; other site
696127002348	dimer interface [polypeptide binding]; other site
696127002349	catalytic motif [active]
696127002350	Class I aldolases; Region: Aldolase_Class_I; cl17187
696127002351	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
696127002352	4Fe-4S binding domain; Region: Fer4; pfam00037
696127002353	4Fe-4S binding domain; Region: Fer4; pfam00037
696127002354	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
696127002355	putative coenzyme Q binding site [chemical binding]; other site
696127002356	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
696127002357	RNA/DNA hybrid binding site [nucleotide binding]; other site
696127002358	active site
696127002359	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
696127002360	C-terminal peptidase (prc); Region: prc; TIGR00225
696127002361	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
696127002362	protein binding site [polypeptide binding]; other site
696127002363	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
696127002364	Catalytic dyad [active]
696127002365	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
696127002366	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
696127002367	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
696127002368	NodB motif; other site
696127002369	putative active site [active]
696127002370	putative catalytic site [active]
696127002371	Zn binding site [ion binding]; other site
696127002372	apolipoprotein N-acyltransferase; Region: lnt; TIGR00546
696127002373	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
696127002374	putative active site [active]
696127002375	catalytic triad [active]
696127002376	putative dimer interface [polypeptide binding]; other site
696127002377	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
696127002378	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696127002379	non-specific DNA binding site [nucleotide binding]; other site
696127002380	salt bridge; other site
696127002381	sequence-specific DNA binding site [nucleotide binding]; other site
696127002382	Family of unknown function (DUF577); Region: DUF577; pfam04510
696127002383	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002384	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
696127002385	Ribosomal protein L28 [Translation, ribosomal structure and biogenesis]; Region: RpmB; COG0227
696127002386	ATP-NAD kinase; Region: NAD_kinase; pfam01513
696127002387	inorganic polyphosphate/ATP-NAD kinase; Reviewed; Region: ppnK; PRK04761
696127002388	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
696127002389	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
696127002390	Catalytic site [active]
696127002391	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
696127002392	ribonuclease III; Reviewed; Region: rnc; PRK00102
696127002393	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
696127002394	dimerization interface [polypeptide binding]; other site
696127002395	active site
696127002396	metal binding site [ion binding]; metal-binding site
696127002397	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
696127002398	dsRNA binding site [nucleotide binding]; other site
696127002399	GTPase Era; Reviewed; Region: era; PRK00089
696127002400	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
696127002401	G1 box; other site
696127002402	GTP/Mg2+ binding site [chemical binding]; other site
696127002403	Switch I region; other site
696127002404	G2 box; other site
696127002405	Switch II region; other site
696127002406	G3 box; other site
696127002407	G4 box; other site
696127002408	G5 box; other site
696127002409	KH domain; Region: KH_2; pfam07650
696127002410	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
696127002411	membrane protein insertase; Provisional; Region: PRK01318
696127002412	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
696127002413	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
696127002414	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
696127002415	Ligand Binding Site [chemical binding]; other site
696127002416	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002417	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
696127002418	FliW protein; Region: FliW; cl00740
696127002419	Flagellar hook-associated protein [Cell motility and secretion]; Region: FlgK; COG1256
696127002420	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
696127002421	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
696127002422	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
696127002423	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
696127002424	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
696127002425	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
696127002426	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
696127002427	active site
696127002428	HIGH motif; other site
696127002429	dimer interface [polypeptide binding]; other site
696127002430	KMSKS motif; other site
696127002431	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
696127002432	RNA binding surface [nucleotide binding]; other site
696127002433	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
696127002434	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
696127002435	FtsX-like permease family; Region: FtsX; pfam02687
696127002436	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
696127002437	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
696127002438	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
696127002439	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
696127002440	TrkA-N domain; Region: TrkA_N; pfam02254
696127002441	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
696127002442	pteridine reductase; Provisional; Region: PRK09135
696127002443	NAD(P) binding site [chemical binding]; other site
696127002444	active site
696127002445	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
696127002446	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
696127002447	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696127002448	Mg2+ binding site [ion binding]; other site
696127002449	G-X-G motif; other site
696127002450	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
696127002451	anchoring element; other site
696127002452	dimer interface [polypeptide binding]; other site
696127002453	ATP binding site [chemical binding]; other site
696127002454	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
696127002455	active site
696127002456	putative metal-binding site [ion binding]; other site
696127002457	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
696127002458	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
696127002459	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
696127002460	active site
696127002461	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
696127002462	Smr domain; Region: Smr; pfam01713
696127002463	acyl carrier protein; Provisional; Region: acpP; PRK00982
696127002464	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
696127002465	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
696127002466	dimer interface [polypeptide binding]; other site
696127002467	active site
696127002468	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
696127002469	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
696127002470	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
696127002471	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
696127002472	Phosphoglycerate kinase; Region: PGK; pfam00162
696127002473	substrate binding site [chemical binding]; other site
696127002474	hinge regions; other site
696127002475	ADP binding site [chemical binding]; other site
696127002476	catalytic site [active]
696127002477	heat shock protein 90; Provisional; Region: PRK05218
696127002478	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696127002479	ATP binding site [chemical binding]; other site
696127002480	Mg2+ binding site [ion binding]; other site
696127002481	G-X-G motif; other site
696127002482	4Fe-4S binding domain; Region: Fer4_5; pfam12801
696127002483	4Fe-4S dicluster domain; Region: Fer4_18; pfam13746
696127002484	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
696127002485	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
696127002486	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
696127002487	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
696127002488	ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; Region: ABC_MTABC3_MDL1_MDL2; cd03249
696127002489	Walker A/P-loop; other site
696127002490	ATP binding site [chemical binding]; other site
696127002491	Q-loop/lid; other site
696127002492	ABC transporter signature motif; other site
696127002493	Walker B; other site
696127002494	D-loop; other site
696127002495	H-loop/switch region; other site
696127002496	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
696127002497	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
696127002498	homodimer interface [polypeptide binding]; other site
696127002499	oligonucleotide binding site [chemical binding]; other site
696127002500	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
696127002501	Protein export membrane protein; Region: SecD_SecF; pfam02355
696127002502	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
696127002503	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
696127002504	active site
696127002505	hinge; other site
696127002506	PCRF domain; Region: PCRF; pfam03462
696127002507	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
696127002508	RF-1 domain; Region: RF-1; pfam00472
696127002509	Iron-sulphur cluster assembly; Region: Fe-S_assembly; pfam04384
696127002510	ATP synthase, Delta/Epsilon chain, beta-sandwich domain; Region: ATP-synt_DE_N; pfam02823
696127002511	LBP interface [polypeptide binding]; other site
696127002512	gamma subunit interface [polypeptide binding]; other site
696127002513	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
696127002514	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
696127002515	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
696127002516	alpha subunit interaction interface [polypeptide binding]; other site
696127002517	Walker A motif; other site
696127002518	ATP binding site [chemical binding]; other site
696127002519	Walker B motif; other site
696127002520	inhibitor binding site; inhibition site
696127002521	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
696127002522	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
696127002523	core domain interface [polypeptide binding]; other site
696127002524	delta subunit interface [polypeptide binding]; other site
696127002525	epsilon subunit interface [polypeptide binding]; other site
696127002526	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
696127002527	flagellar protein export ATPase FliI; Region: FliI_clade2; TIGR03497
696127002528	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
696127002529	beta subunit interaction interface [polypeptide binding]; other site
696127002530	Walker A motif; other site
696127002531	ATP binding site [chemical binding]; other site
696127002532	Walker B motif; other site
696127002533	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
696127002534	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
696127002535	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
696127002536	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
696127002537	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
696127002538	nucleotide binding pocket [chemical binding]; other site
696127002539	K-X-D-G motif; other site
696127002540	catalytic site [active]
696127002541	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
696127002542	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
696127002543	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
696127002544	Dimer interface [polypeptide binding]; other site
696127002545	BRCT sequence motif; other site
696127002546	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
696127002547	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
696127002548	motif 1; other site
696127002549	active site
696127002550	motif 2; other site
696127002551	motif 3; other site
696127002552	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
696127002553	DHHA1 domain; Region: DHHA1; pfam02272
696127002554	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08927
696127002555	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
696127002556	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
696127002557	Walker A motif/ATP binding site; other site
696127002558	Walker B motif; other site
696127002559	Cytochrome C biogenesis protein; Region: CcmH; cl01179
696127002560	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
696127002561	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
696127002562	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
696127002563	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
696127002564	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
696127002565	A new structural DNA glycosylase; Region: AlkD_like; cd06561
696127002566	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
696127002567	active site
696127002568	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
696127002569	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
696127002570	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
696127002571	catalytic residues [active]
696127002572	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
696127002573	trimer interface [polypeptide binding]; other site
696127002574	active site
696127002575	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
696127002576	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
696127002577	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
696127002578	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
696127002579	active site
696127002580	homodimer interface [polypeptide binding]; other site
696127002581	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
696127002582	ATP cone domain; Region: ATP-cone; pfam03477
696127002583	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
696127002584	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
696127002585	RNA binding surface [nucleotide binding]; other site
696127002586	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
696127002587	active site
696127002588	Family description; Region: VCBS; pfam13517
696127002589	FeoA domain; Region: FeoA; pfam04023
696127002590	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
696127002591	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
696127002592	G1 box; other site
696127002593	GTP/Mg2+ binding site [chemical binding]; other site
696127002594	G2 box; other site
696127002595	Switch I region; other site
696127002596	G3 box; other site
696127002597	Switch II region; other site
696127002598	G4 box; other site
696127002599	Nucleoside recognition; Region: Gate; pfam07670
696127002600	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
696127002601	Nucleoside recognition; Region: Gate; pfam07670
696127002602	MarR family; Region: MarR_2; cl17246
696127002603	GTA TIM-barrel-like domain; Region: GTA_TIM; pfam13547
696127002604	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002605	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
696127002606	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
696127002607	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
696127002608	phosphate binding site [ion binding]; other site
696127002609	DNA polymerase III subunit beta; Validated; Region: PRK05643
696127002610	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
696127002611	putative DNA binding surface [nucleotide binding]; other site
696127002612	dimer interface [polypeptide binding]; other site
696127002613	beta-clamp/clamp loader binding surface; other site
696127002614	beta-clamp/translesion DNA polymerase binding surface; other site
696127002615	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696127002616	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696127002617	ABC transporter signature motif; other site
696127002618	Walker B; other site
696127002619	D-loop; other site
696127002620	H-loop/switch region; other site
696127002621	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
696127002622	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
696127002623	NADH dehydrogenase subunit G; Validated; Region: PRK09130
696127002624	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
696127002625	catalytic loop [active]
696127002626	iron binding site [ion binding]; other site
696127002627	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
696127002628	MopB_Res_Cmplx1_Nad11: The second domain of the Nad11/75-kDa subunit of the NADH-quinone oxidoreductase/respiratory complex I/NADH dehydrogenase-1(NDH-1) of eukaryotes and the Nqo3/G subunit of alphaproteobacteria NDH-1. The NADH-quinone oxidoreductase...; Region: MopB_Res-Cmplx1_Nad11; cd02773
696127002629	Domain of unknown function (DUF1982); Region: DUF1982; pfam09326
696127002630	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
696127002631	PspC domain; Region: PspC; cl00864
696127002632	Cytochrome c; Region: Cytochrom_C; pfam00034
696127002633	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
696127002634	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
696127002635	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
696127002636	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
696127002637	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
696127002638	D-pathway; other site
696127002639	Putative water exit pathway; other site
696127002640	K-pathway; other site
696127002641	Binuclear center (active site) [active]
696127002642	Family description; Region: DsbD_2; pfam13386
696127002643	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
696127002644	active site
696127002645	Trp docking motif [polypeptide binding]; other site
696127002646	PQQ-like domain; Region: PQQ_2; pfam13360
696127002647	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696127002648	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696127002649	putative substrate translocation pore; other site
696127002650	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
696127002651	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
696127002652	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
696127002653	active site
696127002654	HIGH motif; other site
696127002655	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
696127002656	KMSK motif region; other site
696127002657	tRNA binding surface [nucleotide binding]; other site
696127002658	DALR anticodon binding domain; Region: DALR_1; smart00836
696127002659	anticodon binding site; other site
696127002660	Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823
696127002661	BON domain; Region: BON; pfam04972
696127002662	BON domain; Region: BON; pfam04972
696127002663	Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only]; Region: COG3178
696127002664	Phosphotransferase enzyme family; Region: APH; pfam01636
696127002665	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
696127002666	NTP_transferase_like_1 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_1; cd06422
696127002667	Substrate binding site; other site
696127002668	metal-binding site
696127002669	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
696127002670	oligomerisation interface [polypeptide binding]; other site
696127002671	mobile loop; other site
696127002672	roof hairpin; other site
696127002673	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
696127002674	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
696127002675	ring oligomerisation interface [polypeptide binding]; other site
696127002676	ATP/Mg binding site [chemical binding]; other site
696127002677	hinge regions; other site
696127002678	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
696127002679	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
696127002680	S-adenosylmethionine synthetase; Validated; Region: PRK05250
696127002681	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
696127002682	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
696127002683	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
696127002684	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
696127002685	putative acyl-acceptor binding pocket; other site
696127002686	Apolipoprotein O; Region: ApoO; pfam09769
696127002687	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
696127002688	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696127002689	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
696127002690	Walker A/P-loop; other site
696127002691	ATP binding site [chemical binding]; other site
696127002692	Q-loop/lid; other site
696127002693	ABC transporter signature motif; other site
696127002694	Walker B; other site
696127002695	D-loop; other site
696127002696	H-loop/switch region; other site
696127002697	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
696127002698	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
696127002699	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
696127002700	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
696127002701	homotetramer interface [polypeptide binding]; other site
696127002702	NAD(P) binding site [chemical binding]; other site
696127002703	homodimer interface [polypeptide binding]; other site
696127002704	active site
696127002705	Predicted ATPase [General function prediction only]; Region: COG1485
696127002706	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
696127002707	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
696127002708	catalytic residues [active]
696127002709	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
696127002710	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
696127002711	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
696127002712	ATP-grasp domain; Region: ATP-grasp_4; cl17255
696127002713	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
696127002714	Cell division protein FtsQ; Region: FtsQ; pfam03799
696127002715	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
696127002716	Cell division protein FtsA; Region: FtsA; smart00842
696127002717	Cell division protein FtsA; Region: FtsA; pfam14450
696127002718	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
696127002719	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
696127002720	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
696127002721	Domain of unknown function (DUF2610); Region: DUF2610; pfam11020
696127002722	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
696127002723	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
696127002724	nucleotide binding site [chemical binding]; other site
696127002725	CutA1 divalent ion tolerance protein; Region: CutA1; cl00584
696127002726	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
696127002727	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
696127002728	Conjugal transfer protein TraD; Region: TraD; pfam06412
696127002729	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
696127002730	Conserved hypothetical protein 2217 (DUF2460); Region: DUF2460; cl02268
696127002731	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
696127002732	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
696127002733	transmembrane helices; other site
696127002734	Uncharacterized conserved protein (DUF2163); Region: DUF2163; pfam09931
696127002735	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
696127002736	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
696127002737	Walker A motif; other site
696127002738	ATP binding site [chemical binding]; other site
696127002739	Walker B motif; other site
696127002740	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
696127002741	Colicin V production protein; Region: Colicin_V; pfam02674
696127002742	EamA-like transporter family; Region: EamA; pfam00892
696127002743	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
696127002744	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
696127002745	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
696127002746	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
696127002747	G1 box; other site
696127002748	putative GEF interaction site [polypeptide binding]; other site
696127002749	GTP/Mg2+ binding site [chemical binding]; other site
696127002750	Switch I region; other site
696127002751	G2 box; other site
696127002752	G3 box; other site
696127002753	Switch II region; other site
696127002754	G4 box; other site
696127002755	G5 box; other site
696127002756	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
696127002757	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
696127002758	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
696127002759	Qi binding site; other site
696127002760	intrachain domain interface; other site
696127002761	interchain domain interface [polypeptide binding]; other site
696127002762	cytochrome b; Provisional; Region: CYTB; MTH00156
696127002763	heme bH binding site [chemical binding]; other site
696127002764	heme bL binding site [chemical binding]; other site
696127002765	Qo binding site; other site
696127002766	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cd00290
696127002767	interchain domain interface [polypeptide binding]; other site
696127002768	intrachain domain interface; other site
696127002769	Qi binding site; other site
696127002770	Qo binding site; other site
696127002771	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
696127002772	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
696127002773	[2Fe-2S] cluster binding site [ion binding]; other site
696127002774	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
696127002775	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002776	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696127002777	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696127002778	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
696127002779	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696127002780	Walker A motif; other site
696127002781	ATP binding site [chemical binding]; other site
696127002782	Walker B motif; other site
696127002783	arginine finger; other site
696127002784	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
696127002785	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
696127002786	Walker A/P-loop; other site
696127002787	ATP binding site [chemical binding]; other site
696127002788	ABC transporter; Region: ABC_tran; pfam00005
696127002789	Q-loop/lid; other site
696127002790	ABC transporter signature motif; other site
696127002791	Walker B; other site
696127002792	D-loop; other site
696127002793	H-loop/switch region; other site
696127002794	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
696127002795	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
696127002796	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3807
696127002797	Bacterial SH3 domain; Region: SH3_4; pfam06347
696127002798	Bacterial SH3 domain; Region: SH3_4; pfam06347
696127002799	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
696127002800	active site
696127002801	HIGH motif; other site
696127002802	nucleotide binding site [chemical binding]; other site
696127002803	Transposase; Region: DEDD_Tnp_IS110; pfam01548
696127002804	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
696127002805	Phage-related protein [Function unknown]; Region: COG4695; cl01923
696127002806	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
696127002807	active site residue [active]