-- dump date   	20140619_023836
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
658172000001	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
658172000002	putative active site [active]
658172000003	Ap4A binding site [chemical binding]; other site
658172000004	nudix motif; other site
658172000005	putative metal binding site [ion binding]; other site
658172000006	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
658172000007	NodB motif; other site
658172000008	putative active site [active]
658172000009	putative catalytic site [active]
658172000010	Zn binding site [ion binding]; other site
658172000011	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
658172000012	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
658172000013	Walker A/P-loop; other site
658172000014	ATP binding site [chemical binding]; other site
658172000015	Q-loop/lid; other site
658172000016	ABC transporter signature motif; other site
658172000017	Walker B; other site
658172000018	D-loop; other site
658172000019	H-loop/switch region; other site
658172000020	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
658172000021	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
658172000022	dimer interface [polypeptide binding]; other site
658172000023	conserved gate region; other site
658172000024	putative PBP binding loops; other site
658172000025	ABC-ATPase subunit interface; other site
658172000026	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
658172000027	dimer interface [polypeptide binding]; other site
658172000028	conserved gate region; other site
658172000029	putative PBP binding loops; other site
658172000030	ABC-ATPase subunit interface; other site
658172000031	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
658172000032	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
658172000033	Oligomerisation domain; Region: Oligomerisation; cl00519
658172000034	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
658172000035	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
658172000036	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
658172000037	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
658172000038	dimerization interface [polypeptide binding]; other site
658172000039	putative ATP binding site [chemical binding]; other site
658172000040	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
658172000041	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
658172000042	active site
658172000043	substrate binding site [chemical binding]; other site
658172000044	cosubstrate binding site; other site
658172000045	catalytic site [active]
658172000046	Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961
658172000047	TadE-like protein; Region: TadE; pfam07811
658172000048	Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961
658172000049	TadE-like protein; Region: TadE; pfam07811
658172000050	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
658172000051	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
658172000052	active site
658172000053	HIGH motif; other site
658172000054	nucleotide binding site [chemical binding]; other site
658172000055	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
658172000056	KMSKS motif; other site
658172000057	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
658172000058	Predicted permeases [General function prediction only]; Region: RarD; COG2962
658172000059	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
658172000060	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
658172000061	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
658172000062	Walker A/P-loop; other site
658172000063	ATP binding site [chemical binding]; other site
658172000064	Q-loop/lid; other site
658172000065	ABC transporter signature motif; other site
658172000066	Walker B; other site
658172000067	D-loop; other site
658172000068	H-loop/switch region; other site
658172000069	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
658172000070	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
658172000071	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
658172000072	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
658172000073	putative active site [active]
658172000074	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
658172000075	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
658172000076	putative acyl-acceptor binding pocket; other site
658172000077	Methyltransferase domain; Region: Methyltransf_11; pfam08241
658172000078	Methyltransferase domain; Region: Methyltransf_23; pfam13489
658172000079	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
658172000080	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
658172000081	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
658172000082	HSP70 interaction site [polypeptide binding]; other site
658172000083	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
658172000084	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
658172000085	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
658172000086	active site
658172000087	DNA binding site [nucleotide binding]
658172000088	Int/Topo IB signature motif; other site
658172000089	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
658172000090	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
658172000091	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
658172000092	K+-transporting ATPase, c chain; Region: KdpC; cl00944
658172000093	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
658172000094	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
658172000095	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
658172000096	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
658172000097	catalytic residue [active]
658172000098	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
658172000099	TPR motif; other site
658172000100	binding surface
658172000101	Tetratricopeptide repeat; Region: TPR_16; pfam13432
658172000102	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
658172000103	TPR motif; other site
658172000104	binding surface
658172000105	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
658172000106	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
658172000107	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
658172000108	C-terminal domain interface [polypeptide binding]; other site
658172000109	GSH binding site (G-site) [chemical binding]; other site
658172000110	dimer interface [polypeptide binding]; other site
658172000111	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cd00299
658172000112	N-terminal domain interface [polypeptide binding]; other site
658172000113	dimer interface [polypeptide binding]; other site
658172000114	substrate binding pocket (H-site) [chemical binding]; other site
658172000115	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
658172000116	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
658172000117	putative NAD(P) binding site [chemical binding]; other site
658172000118	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
658172000119	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
658172000120	Walker A/P-loop; other site
658172000121	ATP binding site [chemical binding]; other site
658172000122	Q-loop/lid; other site
658172000123	ABC transporter signature motif; other site
658172000124	Walker B; other site
658172000125	D-loop; other site
658172000126	H-loop/switch region; other site
658172000127	ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; pfam09821
658172000128	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
658172000129	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
658172000130	dimer interface [polypeptide binding]; other site
658172000131	conserved gate region; other site
658172000132	putative PBP binding loops; other site
658172000133	ABC-ATPase subunit interface; other site
658172000134	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
658172000135	dimer interface [polypeptide binding]; other site
658172000136	conserved gate region; other site
658172000137	putative PBP binding loops; other site
658172000138	ABC-ATPase subunit interface; other site
658172000139	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
658172000140	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
658172000141	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
658172000142	GIY-YIG motif/motif A; other site
658172000143	active site
658172000144	catalytic site [active]
658172000145	putative DNA binding site [nucleotide binding]; other site
658172000146	metal binding site [ion binding]; metal-binding site
658172000147	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
658172000148	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
658172000149	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
658172000150	DEAD-like helicases superfamily; Region: DEXDc; smart00487
658172000151	ATP binding site [chemical binding]; other site
658172000152	putative Mg++ binding site [ion binding]; other site
658172000153	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
658172000154	nucleotide binding region [chemical binding]; other site
658172000155	ATP-binding site [chemical binding]; other site
658172000156	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
658172000157	RNA binding site [nucleotide binding]; other site
658172000158	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
658172000159	aspartate aminotransferase; Provisional; Region: PRK05764
658172000160	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
658172000161	pyridoxal 5'-phosphate binding site [chemical binding]; other site
658172000162	homodimer interface [polypeptide binding]; other site
658172000163	catalytic residue [active]
658172000164	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
658172000165	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
658172000166	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
658172000167	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
658172000168	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
658172000169	substrate-cofactor binding pocket; other site
658172000170	pyridoxal 5'-phosphate binding site [chemical binding]; other site
658172000171	catalytic residue [active]
658172000172	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
658172000173	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
658172000174	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
658172000175	active site
658172000176	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
658172000177	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
658172000178	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
658172000179	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
658172000180	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
658172000181	active site
658172000182	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
658172000183	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
658172000184	active site
658172000185	metal binding site [ion binding]; metal-binding site
658172000186	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
658172000187	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
658172000188	RNA binding surface [nucleotide binding]; other site
658172000189	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
658172000190	active site
658172000191	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
658172000192	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
658172000193	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
658172000194	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
658172000195	DNA binding residues [nucleotide binding]
658172000196	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
658172000197	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
658172000198	GDP-binding site [chemical binding]; other site
658172000199	ACT binding site; other site
658172000200	IMP binding site; other site
658172000201	F0F1 ATP synthase subunit epsilon; Provisional; Region: atpC; PRK14736
658172000202	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
658172000203	gamma subunit interface [polypeptide binding]; other site
658172000204	epsilon subunit interface [polypeptide binding]; other site
658172000205	LBP interface [polypeptide binding]; other site
658172000206	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
658172000207	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
658172000208	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
658172000209	alpha subunit interaction interface [polypeptide binding]; other site
658172000210	Walker A motif; other site
658172000211	ATP binding site [chemical binding]; other site
658172000212	Walker B motif; other site
658172000213	inhibitor binding site; inhibition site
658172000214	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
658172000215	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
658172000216	core domain interface [polypeptide binding]; other site
658172000217	delta subunit interface [polypeptide binding]; other site
658172000218	epsilon subunit interface [polypeptide binding]; other site
658172000219	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
658172000220	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
658172000221	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
658172000222	beta subunit interaction interface [polypeptide binding]; other site
658172000223	Walker A motif; other site
658172000224	ATP binding site [chemical binding]; other site
658172000225	Walker B motif; other site
658172000226	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
658172000227	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13429
658172000228	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
658172000229	primosome assembly protein PriA; Validated; Region: PRK05580
658172000230	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
658172000231	ATP binding site [chemical binding]; other site
658172000232	putative Mg++ binding site [ion binding]; other site
658172000233	helicase superfamily c-terminal domain; Region: HELICc; smart00490
658172000234	nucleotide binding region [chemical binding]; other site
658172000235	ATP-binding site [chemical binding]; other site
658172000236	Transcriptional regulator; Region: Rrf2; cl17282
658172000237	Rrf2 family protein; Region: rrf2_super; TIGR00738
658172000238	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
658172000239	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
658172000240	putative dimer interface [polypeptide binding]; other site
658172000241	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
658172000242	Flavoprotein; Region: Flavoprotein; pfam02441
658172000243	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
658172000244	ABC1 family; Region: ABC1; cl17513
658172000245	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
658172000246	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
658172000247	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
658172000248	S-adenosylmethionine binding site [chemical binding]; other site
658172000249	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
658172000250	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
658172000251	DNA binding site [nucleotide binding]
658172000252	catalytic residue [active]
658172000253	H2TH interface [polypeptide binding]; other site
658172000254	putative catalytic residues [active]
658172000255	turnover-facilitating residue; other site
658172000256	intercalation triad [nucleotide binding]; other site
658172000257	8OG recognition residue [nucleotide binding]; other site
658172000258	putative reading head residues; other site
658172000259	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
658172000260	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
658172000261	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
658172000262	DnaA N-terminal domain; Region: DnaA_N; pfam11638
658172000263	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
658172000264	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172000265	Walker A motif; other site
658172000266	ATP binding site [chemical binding]; other site
658172000267	Walker B motif; other site
658172000268	arginine finger; other site
658172000269	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
658172000270	DnaA box-binding interface [nucleotide binding]; other site
658172000271	coproporphyrinogen III oxidase; Provisional; Region: PRK09057
658172000272	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
658172000273	FeS/SAM binding site; other site
658172000274	HemN C-terminal domain; Region: HemN_C; pfam06969
658172000275	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
658172000276	active site
658172000277	dimerization interface [polypeptide binding]; other site
658172000278	ribonuclease PH; Reviewed; Region: rph; PRK00173
658172000279	Ribonuclease PH; Region: RNase_PH_bact; cd11362
658172000280	hexamer interface [polypeptide binding]; other site
658172000281	active site
658172000282	Creatinine amidohydrolase; Region: Creatininase; pfam02633
658172000283	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
658172000284	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
658172000285	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
658172000286	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
658172000287	Ligand binding site [chemical binding]; other site
658172000288	Electron transfer flavoprotein domain; Region: ETF; pfam01012
658172000289	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
658172000290	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
658172000291	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
658172000292	argininosuccinate lyase; Provisional; Region: PRK00855
658172000293	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
658172000294	active sites [active]
658172000295	tetramer interface [polypeptide binding]; other site
658172000296	diaminopimelate decarboxylase; Region: lysA; TIGR01048
658172000297	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
658172000298	active site
658172000299	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
658172000300	substrate binding site [chemical binding]; other site
658172000301	catalytic residues [active]
658172000302	dimer interface [polypeptide binding]; other site
658172000303	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
658172000304	Flagellar basal body-associated protein FliL; Region: FliL; pfam03748
658172000305	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
658172000306	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
658172000307	Uncharacterized conserved protein [Function unknown]; Region: COG3334
658172000308	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
658172000309	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
658172000310	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
658172000311	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
658172000312	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
658172000313	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12691
658172000314	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
658172000315	Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139
658172000316	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK12782
658172000317	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
658172000318	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
658172000319	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK06003
658172000320	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
658172000321	flagellum-specific ATP synthase; Validated; Region: fliI; PRK06002
658172000322	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
658172000323	Walker A motif; other site
658172000324	ATP binding site [chemical binding]; other site
658172000325	Walker B motif; other site
658172000326	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12642
658172000327	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
658172000328	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
658172000329	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
658172000330	Flagellar motor switch protein [Cell motility and secretion]; Region: FliM; COG1868
658172000331	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
658172000332	flagellar motor switch protein FliN; Region: fliN; TIGR02480
658172000333	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
658172000334	MgtE intracellular N domain; Region: MgtE_N; cl15244
658172000335	FliG C-terminal domain; Region: FliG_C; pfam01706
658172000336	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
658172000337	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
658172000338	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
658172000339	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
658172000340	DNA binding residues [nucleotide binding]
658172000341	dimerization interface [polypeptide binding]; other site
658172000342	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
658172000343	DNA binding residues [nucleotide binding]
658172000344	dimerization interface [polypeptide binding]; other site
658172000345	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
658172000346	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
658172000347	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
658172000348	glutathione synthetase; Provisional; Region: PRK05246
658172000349	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
658172000350	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
658172000351	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
658172000352	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
658172000353	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
658172000354	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
658172000355	Uncharacterized conserved protein [Function unknown]; Region: COG4983
658172000356	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
658172000357	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
658172000358	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
658172000359	protein binding site [polypeptide binding]; other site
658172000360	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
658172000361	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
658172000362	dimer interface [polypeptide binding]; other site
658172000363	phosphorylation site [posttranslational modification]
658172000364	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
658172000365	ATP binding site [chemical binding]; other site
658172000366	Mg2+ binding site [ion binding]; other site
658172000367	G-X-G motif; other site
658172000368	GrpE; Region: GrpE; pfam01025
658172000369	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
658172000370	dimer interface [polypeptide binding]; other site
658172000371	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
658172000372	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
658172000373	PhoU domain; Region: PhoU; pfam01895
658172000374	PhoU domain; Region: PhoU; pfam01895
658172000375	phosphate transporter ATP-binding protein; Provisional; Region: PRK14235
658172000376	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
658172000377	Walker A/P-loop; other site
658172000378	ATP binding site [chemical binding]; other site
658172000379	Q-loop/lid; other site
658172000380	ABC transporter signature motif; other site
658172000381	Walker B; other site
658172000382	D-loop; other site
658172000383	H-loop/switch region; other site
658172000384	Domain of unknown function (DUF3333); Region: DUF3333; pfam11812
658172000385	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
658172000386	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
658172000387	dimer interface [polypeptide binding]; other site
658172000388	conserved gate region; other site
658172000389	putative PBP binding loops; other site
658172000390	ABC-ATPase subunit interface; other site
658172000391	Phosphate ATP-binding cassette transporter; Region: DUF3708; pfam12501
658172000392	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
658172000393	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
658172000394	dimer interface [polypeptide binding]; other site
658172000395	conserved gate region; other site
658172000396	putative PBP binding loops; other site
658172000397	ABC-ATPase subunit interface; other site
658172000398	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
658172000399	Intracellular septation protein A; Region: IspA; pfam04279
658172000400	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
658172000401	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
658172000402	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
658172000403	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
658172000404	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
658172000405	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
658172000406	signal recognition particle protein; Provisional; Region: PRK10867
658172000407	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
658172000408	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
658172000409	P loop; other site
658172000410	GTP binding site [chemical binding]; other site
658172000411	Signal peptide binding domain; Region: SRP_SPB; pfam02978
658172000412	Ribosomal protein S16 [Translation, ribosomal structure and biogenesis]; Region: RpsP; COG0228
658172000413	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
658172000414	RimM N-terminal domain; Region: RimM; pfam01782
658172000415	PRC-barrel domain; Region: PRC; pfam05239
658172000416	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
658172000417	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
658172000418	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
658172000419	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
658172000420	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
658172000421	ABC-type Zn2+ transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: ZnuA; COG4531
658172000422	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
658172000423	metal binding site [ion binding]; metal-binding site
658172000424	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
658172000425	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
658172000426	Walker A/P-loop; other site
658172000427	ATP binding site [chemical binding]; other site
658172000428	Q-loop/lid; other site
658172000429	ABC transporter signature motif; other site
658172000430	Walker B; other site
658172000431	D-loop; other site
658172000432	H-loop/switch region; other site
658172000433	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
658172000434	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
658172000435	ABC-ATPase subunit  interface; other site
658172000436	dimer interface [polypeptide binding]; other site
658172000437	putative PBP binding regions; other site
658172000438	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
658172000439	Ferritin-like domain; Region: Ferritin; pfam00210
658172000440	ferroxidase diiron center [ion binding]; other site
658172000441	Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064
658172000442	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
658172000443	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
658172000444	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
658172000445	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
658172000446	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
658172000447	ATP binding site [chemical binding]; other site
658172000448	Walker A motif; other site
658172000449	hexamer interface [polypeptide binding]; other site
658172000450	Walker B motif; other site
658172000451	AAA domain; Region: AAA_31; pfam13614
658172000452	This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111
658172000453	This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111
658172000454	Pilus biogenesis CpaD protein (pilus_cpaD); Region: Pilus_CpaD; pfam09476
658172000455	Type IV pili component [Cell motility and secretion]; Region: COG5461
658172000456	Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion]; Region: CpaC; COG4964
658172000457	Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629
658172000458	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
658172000459	Flp pilus assembly protein CpaB [Intracellular trafficking and secretion]; Region: CpaB; COG3745
658172000460	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
658172000461	Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960
658172000462	Flp/Fap pilin component; Region: Flp_Fap; cl01585
658172000463	Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion]; Region: Flp; COG3847
658172000464	Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion]; Region: Flp; COG3847
658172000465	Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion]; Region: Flp; COG3847
658172000466	Flp/Fap pilin component; Region: Flp_Fap; cl01585
658172000467	Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629
658172000468	Uncharacterized conserved protein [Function unknown]; Region: COG2835
658172000469	Uncharacterized protein, similar to the N-terminal domain of Lon protease [General function prediction only]; Region: COG2802
658172000470	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
658172000471	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
658172000472	dimer interface [polypeptide binding]; other site
658172000473	active site
658172000474	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
658172000475	catalytic residues [active]
658172000476	substrate binding site [chemical binding]; other site
658172000477	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
658172000478	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
658172000479	NAD(P) binding pocket [chemical binding]; other site
658172000480	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
658172000481	Fe-S cluster binding site [ion binding]; other site
658172000482	active site
658172000483	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
658172000484	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
658172000485	Walker A/P-loop; other site
658172000486	ATP binding site [chemical binding]; other site
658172000487	Q-loop/lid; other site
658172000488	ABC transporter signature motif; other site
658172000489	Walker B; other site
658172000490	D-loop; other site
658172000491	H-loop/switch region; other site
658172000492	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
658172000493	OstA-like protein; Region: OstA; pfam03968
658172000494	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5375
658172000495	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
658172000496	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
658172000497	tandem repeat interface [polypeptide binding]; other site
658172000498	oligomer interface [polypeptide binding]; other site
658172000499	active site residues [active]
658172000500	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
658172000501	IHF - DNA interface [nucleotide binding]; other site
658172000502	IHF dimer interface [polypeptide binding]; other site
658172000503	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
658172000504	lipoprotein signal peptidase; Provisional; Region: PRK14787
658172000505	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
658172000506	MutS domain I; Region: MutS_I; pfam01624
658172000507	MutS domain II; Region: MutS_II; pfam05188
658172000508	MutS domain III; Region: MutS_III; pfam05192
658172000509	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
658172000510	Walker A/P-loop; other site
658172000511	ATP binding site [chemical binding]; other site
658172000512	Q-loop/lid; other site
658172000513	ABC transporter signature motif; other site
658172000514	Walker B; other site
658172000515	D-loop; other site
658172000516	H-loop/switch region; other site
658172000517	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
658172000518	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
658172000519	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
658172000520	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
658172000521	Transglycosylase; Region: Transgly; pfam00912
658172000522	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
658172000523	peptide chain release factor 2; Validated; Region: prfB; PRK00578
658172000524	This domain is found in peptide chain release factors; Region: PCRF; smart00937
658172000525	RF-1 domain; Region: RF-1; pfam00472
658172000526	inorganic polyphosphate/ATP-NAD kinase; Reviewed; Region: ppnK; PRK04761
658172000527	ATP-NAD kinase; Region: NAD_kinase; pfam01513
658172000528	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
658172000529	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
658172000530	substrate binding pocket [chemical binding]; other site
658172000531	chain length determination region; other site
658172000532	substrate-Mg2+ binding site; other site
658172000533	catalytic residues [active]
658172000534	aspartate-rich region 1; other site
658172000535	active site lid residues [active]
658172000536	aspartate-rich region 2; other site
658172000537	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
658172000538	Methyltransferase domain; Region: Methyltransf_26; pfam13659
658172000539	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
658172000540	dimer interface [polypeptide binding]; other site
658172000541	motif 1; other site
658172000542	active site
658172000543	motif 2; other site
658172000544	motif 3; other site
658172000545	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
658172000546	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
658172000547	catalytic residues [active]
658172000548	structural protein; Region: PHA01972
658172000549	hypothetical protein; Region: PHA00661
658172000550	hypothetical protein; Region: PHA00662
658172000551	hypothetical protein; Region: PHA00670
658172000552	Bacteriophage head to tail connecting protein; Region: Head-tail_con; pfam12236
658172000553	Terminase-like family; Region: Terminase_6; pfam03237
658172000554	Helix-turn-helix domain; Region: HTH_19; pfam12844
658172000555	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
658172000556	non-specific DNA binding site [nucleotide binding]; other site
658172000557	salt bridge; other site
658172000558	sequence-specific DNA binding site [nucleotide binding]; other site
658172000559	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
658172000560	Prophage antirepressor [Transcription]; Region: COG3617
658172000561	BRO family, N-terminal domain; Region: Bro-N; smart01040
658172000562	Predicted nucleotide-binding protein containing TIR-like domain; Region: TIR-like; cl17861
658172000563	Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cl02488
658172000564	linker region; other site
658172000565	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
658172000566	Primase C terminal 2 (PriCT-2); Region: PriCT_2; pfam08707
658172000567	D5 N terminal like; Region: D5_N; pfam08706
658172000568	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
658172000569	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
658172000570	Protein of unknown function (DUF2800); Region: DUF2800; pfam10926
658172000571	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; cl10713
658172000572	Prophage antirepressor [Transcription]; Region: COG3617
658172000573	BRO family, N-terminal domain; Region: Bro-N; smart01040
658172000574	Protein of unknown function (DUF2815); Region: DUF2815; pfam10991
658172000575	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
658172000576	active site
658172000577	substrate binding site [chemical binding]; other site
658172000578	Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A; cl02626
658172000579	active site
658172000580	DNA binding site [nucleotide binding]
658172000581	catalytic site [active]
658172000582	VRR-NUC domain; Region: VRR_NUC; pfam08774
658172000583	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
658172000584	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
658172000585	ATP binding site [chemical binding]; other site
658172000586	putative Mg++ binding site [ion binding]; other site
658172000587	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
658172000588	NAD-dependent DNA ligase LigA; Provisional; Region: ligA; PRK14351
658172000589	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
658172000590	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
658172000591	active site
658172000592	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
658172000593	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
658172000594	active site
658172000595	catalytic residues [active]
658172000596	DNA binding site [nucleotide binding]
658172000597	Int/Topo IB signature motif; other site
658172000598	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
658172000599	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
658172000600	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
658172000601	FAD binding domain; Region: FAD_binding_4; pfam01565
658172000602	recombination protein RecR; Reviewed; Region: recR; PRK00076
658172000603	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
658172000604	putative active site [active]
658172000605	putative metal-binding site [ion binding]; other site
658172000606	tetramer interface [polypeptide binding]; other site
658172000607	hypothetical protein; Validated; Region: PRK00153
658172000608	DNA polymerase III gamma and tau subunits C terminal; Region: DUF3646; pfam12362
658172000609	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
658172000610	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172000611	Walker A motif; other site
658172000612	ATP binding site [chemical binding]; other site
658172000613	Walker B motif; other site
658172000614	arginine finger; other site
658172000615	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
658172000616	Bacterial SH3 domain; Region: SH3_4; pfam06347
658172000617	Bacterial SH3 domain; Region: SH3_4; pfam06347
658172000618	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
658172000619	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
658172000620	Ligand binding site; other site
658172000621	oligomer interface; other site
658172000622	recombination protein F; Reviewed; Region: recF; PRK00064
658172000623	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
658172000624	Walker A/P-loop; other site
658172000625	ATP binding site [chemical binding]; other site
658172000626	Q-loop/lid; other site
658172000627	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
658172000628	ABC transporter signature motif; other site
658172000629	Walker B; other site
658172000630	D-loop; other site
658172000631	H-loop/switch region; other site
658172000632	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
658172000633	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
658172000634	Protein of unknown function (DUF1009); Region: DUF1009; cl09182
658172000635	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
658172000636	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
658172000637	active site
658172000638	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
658172000639	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
658172000640	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
658172000641	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
658172000642	trimer interface [polypeptide binding]; other site
658172000643	active site
658172000644	UDP-GlcNAc binding site [chemical binding]; other site
658172000645	lipid binding site [chemical binding]; lipid-binding site
658172000646	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
658172000647	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
658172000648	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
658172000649	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
658172000650	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
658172000651	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
658172000652	Surface antigen; Region: Bac_surface_Ag; pfam01103
658172000653	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
658172000654	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
658172000655	active site
658172000656	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
658172000657	protein binding site [polypeptide binding]; other site
658172000658	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
658172000659	putative substrate binding region [chemical binding]; other site
658172000660	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
658172000661	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
658172000662	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14834
658172000663	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
658172000664	catalytic residue [active]
658172000665	putative FPP diphosphate  binding site; other site
658172000666	putative FPP binding hydrophobic cleft; other site
658172000667	dimer interface [polypeptide binding]; other site
658172000668	putative IPP diphosphate binding site; other site
658172000669	ribosome recycling factor; Reviewed; Region: frr; PRK00083
658172000670	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
658172000671	hinge region; other site
658172000672	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
658172000673	putative nucleotide binding site [chemical binding]; other site
658172000674	uridine monophosphate binding site [chemical binding]; other site
658172000675	homohexameric interface [polypeptide binding]; other site
658172000676	elongation factor Ts; Provisional; Region: tsf; PRK09377
658172000677	UBA/TS-N domain; Region: UBA; pfam00627
658172000678	Elongation factor TS; Region: EF_TS; pfam00889
658172000679	Elongation factor TS; Region: EF_TS; pfam00889
658172000680	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
658172000681	rRNA interaction site [nucleotide binding]; other site
658172000682	S8 interaction site; other site
658172000683	putative laminin-1 binding site; other site
658172000684	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
658172000685	HIT family signature motif; other site
658172000686	catalytic residue [active]
658172000687	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
658172000688	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
658172000689	trimer interface [polypeptide binding]; other site
658172000690	active site
658172000691	substrate binding site [chemical binding]; other site
658172000692	CoA binding site [chemical binding]; other site
658172000693	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
658172000694	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
658172000695	metal binding site [ion binding]; metal-binding site
658172000696	dimer interface [polypeptide binding]; other site
658172000697	Predicted transcriptional regulator [Transcription]; Region: COG4957
658172000698	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
658172000699	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
658172000700	RNase E interface [polypeptide binding]; other site
658172000701	trimer interface [polypeptide binding]; other site
658172000702	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
658172000703	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
658172000704	RNase E interface [polypeptide binding]; other site
658172000705	trimer interface [polypeptide binding]; other site
658172000706	active site
658172000707	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
658172000708	putative nucleic acid binding region [nucleotide binding]; other site
658172000709	G-X-X-G motif; other site
658172000710	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
658172000711	RNA binding site [nucleotide binding]; other site
658172000712	domain interface; other site
658172000713	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
658172000714	16S/18S rRNA binding site [nucleotide binding]; other site
658172000715	S13e-L30e interaction site [polypeptide binding]; other site
658172000716	25S rRNA binding site [nucleotide binding]; other site
658172000717	Ribosome-binding factor A; Region: RBFA; cl00542
658172000718	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
658172000719	Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; Region: InfB; COG0532
658172000720	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
658172000721	G1 box; other site
658172000722	putative GEF interaction site [polypeptide binding]; other site
658172000723	GTP/Mg2+ binding site [chemical binding]; other site
658172000724	Switch I region; other site
658172000725	G2 box; other site
658172000726	G3 box; other site
658172000727	Switch II region; other site
658172000728	G4 box; other site
658172000729	G5 box; other site
658172000730	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
658172000731	Translation-initiation factor 2; Region: IF-2; pfam11987
658172000732	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
658172000733	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
658172000734	NusA N-terminal domain; Region: NusA_N; pfam08529
658172000735	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
658172000736	RNA binding site [nucleotide binding]; other site
658172000737	homodimer interface [polypeptide binding]; other site
658172000738	NusA-like KH domain; Region: KH_5; pfam13184
658172000739	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
658172000740	G-X-X-G motif; other site
658172000741	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
658172000742	ribosome maturation protein RimP; Reviewed; Region: PRK00092
658172000743	Sm and related proteins; Region: Sm_like; cl00259
658172000744	heptamer interface [polypeptide binding]; other site
658172000745	Sm1 motif; other site
658172000746	hexamer interface [polypeptide binding]; other site
658172000747	RNA binding site [nucleotide binding]; other site
658172000748	Sm2 motif; other site
658172000749	GtrA-like protein; Region: GtrA; pfam04138
658172000750	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
658172000751	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
658172000752	generic binding surface II; other site
658172000753	generic binding surface I; other site
658172000754	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
658172000755	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
658172000756	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
658172000757	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
658172000758	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
658172000759	active site
658172000760	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
658172000761	HIGH motif; other site
658172000762	dimer interface [polypeptide binding]; other site
658172000763	KMSKS motif; other site
658172000764	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
658172000765	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
658172000766	Homoserine Kinase, type II. Homoserine kinase is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and...; Region: HomoserineK_II; cd05153
658172000767	putative active site [active]
658172000768	putative substrate binding site [chemical binding]; other site
658172000769	ATP binding site [chemical binding]; other site
658172000770	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
658172000771	RNA/DNA hybrid binding site [nucleotide binding]; other site
658172000772	active site
658172000773	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
658172000774	putative catalytic site [active]
658172000775	putative metal binding site [ion binding]; other site
658172000776	putative phosphate binding site [ion binding]; other site
658172000777	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
658172000778	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
658172000779	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
658172000780	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
658172000781	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
658172000782	Protein of unknown function (DUF1013); Region: DUF1013; cl11533
658172000783	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
658172000784	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
658172000785	catalytic residue [active]
658172000786	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
658172000787	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
658172000788	HIGH motif; other site
658172000789	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
658172000790	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
658172000791	active site
658172000792	KMSKS motif; other site
658172000793	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
658172000794	tRNA binding surface [nucleotide binding]; other site
658172000795	Lipopolysaccharide-assembly; Region: LptE; cl01125
658172000796	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK06585
658172000797	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
658172000798	ParB-like nuclease domain; Region: ParBc; pfam02195
658172000799	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
658172000800	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
658172000801	P-loop; other site
658172000802	Magnesium ion binding site [ion binding]; other site
658172000803	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
658172000804	Magnesium ion binding site [ion binding]; other site
658172000805	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
658172000806	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
658172000807	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
658172000808	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
658172000809	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
658172000810	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
658172000811	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
658172000812	trmE is a tRNA modification GTPase; Region: trmE; cd04164
658172000813	G1 box; other site
658172000814	GTP/Mg2+ binding site [chemical binding]; other site
658172000815	Switch I region; other site
658172000816	G2 box; other site
658172000817	Switch II region; other site
658172000818	G3 box; other site
658172000819	G4 box; other site
658172000820	G5 box; other site
658172000821	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
658172000822	transcription termination factor Rho; Provisional; Region: rho; PRK09376
658172000823	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
658172000824	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
658172000825	RNA binding site [nucleotide binding]; other site
658172000826	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
658172000827	multimer interface [polypeptide binding]; other site
658172000828	Walker A motif; other site
658172000829	ATP binding site [chemical binding]; other site
658172000830	Walker B motif; other site
658172000831	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
658172000832	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
658172000833	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
658172000834	substrate binding site [chemical binding]; other site
658172000835	active site
658172000836	Maf-like protein; Region: Maf; pfam02545
658172000837	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
658172000838	active site
658172000839	dimer interface [polypeptide binding]; other site
658172000840	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
658172000841	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
658172000842	Mg2+ binding site [ion binding]; other site
658172000843	G-X-G motif; other site
658172000844	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
658172000845	anchoring element; other site
658172000846	dimer interface [polypeptide binding]; other site
658172000847	ATP binding site [chemical binding]; other site
658172000848	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
658172000849	active site
658172000850	putative metal-binding site [ion binding]; other site
658172000851	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
658172000852	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4395
658172000853	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
658172000854	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
658172000855	active site
658172000856	catalytic site [active]
658172000857	substrate binding site [chemical binding]; other site
658172000858	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
658172000859	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
658172000860	CoA-binding site [chemical binding]; other site
658172000861	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
658172000862	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
658172000863	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
658172000864	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
658172000865	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
658172000866	catalytic residues [active]
658172000867	double-strand break repair helicase AddA, alphaproteobacterial type; Region: addA_alphas; TIGR02784
658172000868	Part of AAA domain; Region: AAA_19; pfam13245
658172000869	Family description; Region: UvrD_C_2; pfam13538
658172000870	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
658172000871	double-strand break repair protein AddB, alphaproteobacterial type; Region: addB_alphas; TIGR02786
658172000872	RecB family exonuclease [DNA replication, recombination, and repair]; Region: COG2887
658172000873	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
658172000874	PAS fold; Region: PAS_7; pfam12860
658172000875	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
658172000876	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
658172000877	dimer interface [polypeptide binding]; other site
658172000878	phosphorylation site [posttranslational modification]
658172000879	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
658172000880	ATP binding site [chemical binding]; other site
658172000881	Mg2+ binding site [ion binding]; other site
658172000882	G-X-G motif; other site
658172000883	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
658172000884	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
658172000885	active site
658172000886	substrate-binding site [chemical binding]; other site
658172000887	metal-binding site [ion binding]
658172000888	ATP binding site [chemical binding]; other site
658172000889	pantothenate kinase; Provisional; Region: PRK05439
658172000890	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
658172000891	ATP-binding site [chemical binding]; other site
658172000892	CoA-binding site [chemical binding]; other site
658172000893	Mg2+-binding site [ion binding]; other site
658172000894	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
658172000895	active site
658172000896	HslU subunit interaction site [polypeptide binding]; other site
658172000897	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
658172000898	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
658172000899	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172000900	Walker A motif; other site
658172000901	ATP binding site [chemical binding]; other site
658172000902	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
658172000903	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
658172000904	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK05963
658172000905	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
658172000906	dimer interface [polypeptide binding]; other site
658172000907	active site
658172000908	CoA binding pocket [chemical binding]; other site
658172000909	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
658172000910	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
658172000911	inhibitor-cofactor binding pocket; inhibition site
658172000912	pyridoxal 5'-phosphate binding site [chemical binding]; other site
658172000913	catalytic residue [active]
658172000914	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
658172000915	AAA domain; Region: AAA_26; pfam13500
658172000916	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
658172000917	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
658172000918	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
658172000919	catalytic residue [active]
658172000920	biotin synthase; Region: bioB; TIGR00433
658172000921	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
658172000922	FeS/SAM binding site; other site
658172000923	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
658172000924	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
658172000925	feedback inhibition sensing region; other site
658172000926	homohexameric interface [polypeptide binding]; other site
658172000927	nucleotide binding site [chemical binding]; other site
658172000928	N-acetyl-L-glutamate binding site [chemical binding]; other site
658172000929	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
658172000930	G1 box; other site
658172000931	GTP/Mg2+ binding site [chemical binding]; other site
658172000932	Switch I region; other site
658172000933	G2 box; other site
658172000934	G3 box; other site
658172000935	Switch II region; other site
658172000936	G4 box; other site
658172000937	G5 box; other site
658172000938	membrane protein insertase; Provisional; Region: PRK01318
658172000939	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
658172000940	ribonuclease P; Reviewed; Region: rnpA; PRK01313
658172000941	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
658172000942	2'-deoxycytidine 5'-triphosphate deaminase; Provisional; Region: PRK07559
658172000943	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cl00493
658172000944	trimer interface [polypeptide binding]; other site
658172000945	active site
658172000946	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cl00493
658172000947	trimer interface [polypeptide binding]; other site
658172000948	active site
658172000949	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
658172000950	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
658172000951	minor groove reading motif; other site
658172000952	helix-hairpin-helix signature motif; other site
658172000953	substrate binding pocket [chemical binding]; other site
658172000954	active site
658172000955	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
658172000956	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
658172000957	DNA binding and oxoG recognition site [nucleotide binding]
658172000958	Protein of unknown function (DUF721); Region: DUF721; cl02324
658172000959	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
658172000960	Thioredoxin; Region: Thioredoxin_4; pfam13462
658172000961	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
658172000962	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
658172000963	active site
658172000964	phosphorylation site [posttranslational modification]
658172000965	intermolecular recognition site; other site
658172000966	dimerization interface [polypeptide binding]; other site
658172000967	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
658172000968	cytochrome o ubiquinol oxidase subunit II; Region: CyoA; TIGR01433
658172000969	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
658172000970	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
658172000971	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
658172000972	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
658172000973	D-pathway; other site
658172000974	Putative ubiquinol binding site [chemical binding]; other site
658172000975	Low-spin heme (heme b) binding site [chemical binding]; other site
658172000976	Putative water exit pathway; other site
658172000977	Binuclear center (heme o3/CuB) [ion binding]; other site
658172000978	K-pathway; other site
658172000979	Putative proton exit pathway; other site
658172000980	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
658172000981	Subunit I/III interface [polypeptide binding]; other site
658172000982	Subunit III/IV interface [polypeptide binding]; other site
658172000983	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
658172000984	translation initiation factor IF-1; Validated; Region: infA; PRK00276
658172000985	RNA binding site [nucleotide binding]; other site
658172000986	Domain of unknown function (DUF329); Region: DUF329; cl01144
658172000987	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
658172000988	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
658172000989	PAS fold; Region: PAS_3; pfam08447
658172000990	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Region: PAC; smart00086
658172000991	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
658172000992	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
658172000993	metal binding site [ion binding]; metal-binding site
658172000994	active site
658172000995	I-site; other site
658172000996	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
658172000997	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
658172000998	hypothetical protein; Reviewed; Region: PRK12497
658172000999	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
658172001000	DNA methylase; Region: N6_N4_Mtase; pfam01555
658172001001	Fe2+ transport protein; Region: Iron_transport; pfam10634
658172001002	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
658172001003	Iron permease FTR1 family; Region: FTR1; cl00475
658172001004	Predicted periplasmic lipoprotein involved in iron transport [Inorganic ion transport and metabolism]; Region: COG2822
658172001005	Imelysin; Region: Peptidase_M75; cl09159
658172001006	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
658172001007	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
658172001008	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
658172001009	pyridoxal 5'-phosphate binding site [chemical binding]; other site
658172001010	catalytic residue [active]
658172001011	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
658172001012	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
658172001013	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
658172001014	ribonuclease Y; Region: RNase_Y; TIGR03319
658172001015	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK06505
658172001016	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
658172001017	NAD binding site [chemical binding]; other site
658172001018	homotetramer interface [polypeptide binding]; other site
658172001019	homodimer interface [polypeptide binding]; other site
658172001020	substrate binding site [chemical binding]; other site
658172001021	active site
658172001022	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
658172001023	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
658172001024	dimer interface [polypeptide binding]; other site
658172001025	active site
658172001026	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
658172001027	active site 1 [active]
658172001028	dimer interface [polypeptide binding]; other site
658172001029	active site 2 [active]
658172001030	Protein of unknown function (FYDLN_acid); Region: FYDLN_acid; pfam09538
658172001031	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4530
658172001032	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
658172001033	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
658172001034	putative active site [active]
658172001035	cytidylate kinase; Provisional; Region: cmk; PRK00023
658172001036	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
658172001037	CMP-binding site; other site
658172001038	The sites determining sugar specificity; other site
658172001039	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
658172001040	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
658172001041	RNA binding site [nucleotide binding]; other site
658172001042	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
658172001043	RNA binding site [nucleotide binding]; other site
658172001044	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
658172001045	RNA binding site [nucleotide binding]; other site
658172001046	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
658172001047	RNA binding site [nucleotide binding]; other site
658172001048	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
658172001049	RNA binding site [nucleotide binding]; other site
658172001050	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
658172001051	RNA binding site [nucleotide binding]; other site
658172001052	nicotinate phosphoribosyltransferase; Provisional; Region: PRK05321
658172001053	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
658172001054	active site
658172001055	DNA polymerase III subunit beta; Validated; Region: PRK05643
658172001056	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
658172001057	putative DNA binding surface [nucleotide binding]; other site
658172001058	dimer interface [polypeptide binding]; other site
658172001059	beta-clamp/clamp loader binding surface; other site
658172001060	beta-clamp/translesion DNA polymerase binding surface; other site
658172001061	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
658172001062	active site
658172001063	dimer interface [polypeptide binding]; other site
658172001064	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
658172001065	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
658172001066	aconitate hydratase; Validated; Region: PRK09277
658172001067	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
658172001068	substrate binding site [chemical binding]; other site
658172001069	ligand binding site [chemical binding]; other site
658172001070	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
658172001071	substrate binding site [chemical binding]; other site
658172001072	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
658172001073	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
658172001074	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
658172001075	dimer interface [polypeptide binding]; other site
658172001076	phosphorylation site [posttranslational modification]
658172001077	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
658172001078	ATP binding site [chemical binding]; other site
658172001079	Mg2+ binding site [ion binding]; other site
658172001080	G-X-G motif; other site
658172001081	Response regulator receiver domain; Region: Response_reg; pfam00072
658172001082	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
658172001083	active site
658172001084	phosphorylation site [posttranslational modification]
658172001085	intermolecular recognition site; other site
658172001086	dimerization interface [polypeptide binding]; other site
658172001087	isoleucyl-tRNA synthetase; Provisional; Region: ileS; PRK13804
658172001088	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
658172001089	active site
658172001090	HIGH motif; other site
658172001091	nucleotide binding site [chemical binding]; other site
658172001092	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
658172001093	active site
658172001094	KMSKS motif; other site
658172001095	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
658172001096	tRNA binding surface [nucleotide binding]; other site
658172001097	anticodon binding site; other site
658172001098	Predicted transcriptional regulator [Transcription]; Region: COG2932
658172001099	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
658172001100	Catalytic site [active]
658172001101	Protein of unknown function (DUF1036); Region: DUF1036; pfam06282
658172001102	pyruvate kinase; Provisional; Region: PRK06247
658172001103	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
658172001104	domain interfaces; other site
658172001105	active site
658172001106	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
658172001107	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
658172001108	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
658172001109	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
658172001110	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
658172001111	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
658172001112	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
658172001113	ATP-grasp domain; Region: ATP-grasp_4; cl17255
658172001114	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
658172001115	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
658172001116	ATP-grasp domain; Region: ATP-grasp_4; cl17255
658172001117	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
658172001118	IMP binding site; other site
658172001119	dimer interface [polypeptide binding]; other site
658172001120	interdomain contacts; other site
658172001121	partial ornithine binding site; other site
658172001122	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
658172001123	active site
658172001124	hydrophilic channel; other site
658172001125	dimerization interface [polypeptide binding]; other site
658172001126	catalytic residues [active]
658172001127	active site lid [active]
658172001128	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
658172001129	TPR repeat; Region: TPR_11; pfam13414
658172001130	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
658172001131	binding surface
658172001132	TPR motif; other site
658172001133	TPR repeat; Region: TPR_11; pfam13414
658172001134	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
658172001135	binding surface
658172001136	TPR repeat; Region: TPR_11; pfam13414
658172001137	TPR motif; other site
658172001138	TPR repeat; Region: TPR_11; pfam13414
658172001139	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
658172001140	binding surface
658172001141	TPR motif; other site
658172001142	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
658172001143	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
658172001144	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
658172001145	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
658172001146	active site
658172001147	catalytic residues [active]
658172001148	FMN binding site [chemical binding]; other site
658172001149	quinone interaction residues [chemical binding]; other site
658172001150	substrate binding site [chemical binding]; other site
658172001151	ornithine carbamoyltransferase; Provisional; Region: PRK00779
658172001152	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
658172001153	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
658172001154	acetylornithine transaminase protein; Provisional; Region: argD; PRK01278
658172001155	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
658172001156	inhibitor-cofactor binding pocket; inhibition site
658172001157	pyridoxal 5'-phosphate binding site [chemical binding]; other site
658172001158	catalytic residue [active]
658172001159	GcrA cell cycle regulator; Region: GcrA; cl11564
658172001160	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
658172001161	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
658172001162	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
658172001163	Glycoprotease family; Region: Peptidase_M22; pfam00814
658172001164	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
658172001165	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
658172001166	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
658172001167	FeS/SAM binding site; other site
658172001168	TRAM domain; Region: TRAM; pfam01938
658172001169	metal-binding heat shock protein; Provisional; Region: PRK00016
658172001170	FOG: CBS domain [General function prediction only]; Region: COG0517
658172001171	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
658172001172	Transporter associated domain; Region: CorC_HlyC; smart01091
658172001173	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
658172001174	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
658172001175	putative active site [active]
658172001176	putative dimer interface [polypeptide binding]; other site
658172001177	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
658172001178	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
658172001179	non-specific DNA binding site [nucleotide binding]; other site
658172001180	salt bridge; other site
658172001181	sequence-specific DNA binding site [nucleotide binding]; other site
658172001182	S-adenosylmethionine synthetase; Validated; Region: PRK05250
658172001183	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
658172001184	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
658172001185	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
658172001186	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
658172001187	S-adenosylmethionine binding site [chemical binding]; other site
658172001188	GTP-binding protein Der; Reviewed; Region: PRK00093
658172001189	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
658172001190	Switch I region; other site
658172001191	G2 box; other site
658172001192	Switch II region; other site
658172001193	G3 box; other site
658172001194	GTP/Mg2+ binding site [chemical binding]; other site
658172001195	G4 box; other site
658172001196	G5 box; other site
658172001197	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
658172001198	G1 box; other site
658172001199	GTP/Mg2+ binding site [chemical binding]; other site
658172001200	Switch I region; other site
658172001201	G2 box; other site
658172001202	G3 box; other site
658172001203	Switch II region; other site
658172001204	G4 box; other site
658172001205	G5 box; other site
658172001206	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4649
658172001207	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
658172001208	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
658172001209	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
658172001210	catalytic site [active]
658172001211	subunit interface [polypeptide binding]; other site
658172001212	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
658172001213	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
658172001214	dimer interface [polypeptide binding]; other site
658172001215	anticodon binding site; other site
658172001216	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
658172001217	homodimer interface [polypeptide binding]; other site
658172001218	motif 1; other site
658172001219	active site
658172001220	motif 2; other site
658172001221	GAD domain; Region: GAD; pfam02938
658172001222	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
658172001223	active site
658172001224	motif 3; other site
658172001225	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
658172001226	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
658172001227	5S rRNA interface [nucleotide binding]; other site
658172001228	CTC domain interface [polypeptide binding]; other site
658172001229	L16 interface [polypeptide binding]; other site
658172001230	Transcriptional regulators, similar to M. xanthus CarD [Transcription]; Region: COG1329
658172001231	Ferredoxin [Energy production and conversion]; Region: COG1146
658172001232	4Fe-4S binding domain; Region: Fer4; pfam00037
658172001233	Domain of unknown function (DUF3470); Region: DUF3470; pfam11953
658172001234	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
658172001235	FOG: CBS domain [General function prediction only]; Region: COG0517
658172001236	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
658172001237	Transporter associated domain; Region: CorC_HlyC; smart01091
658172001238	GMP synthase; Reviewed; Region: guaA; PRK00074
658172001239	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
658172001240	AMP/PPi binding site [chemical binding]; other site
658172001241	candidate oxyanion hole; other site
658172001242	catalytic triad [active]
658172001243	potential glutamine specificity residues [chemical binding]; other site
658172001244	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
658172001245	ATP Binding subdomain [chemical binding]; other site
658172001246	Ligand Binding sites [chemical binding]; other site
658172001247	Dimerization subdomain; other site
658172001248	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
658172001249	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
658172001250	putative active site [active]
658172001251	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
658172001252	dimer interface [polypeptide binding]; other site
658172001253	phosphorylation site [posttranslational modification]
658172001254	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
658172001255	ATP binding site [chemical binding]; other site
658172001256	Mg2+ binding site [ion binding]; other site
658172001257	G-X-G motif; other site
658172001258	Membrane fusogenic activity; Region: BMFP; cl01115
658172001259	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
658172001260	Uncharacterized conserved protein [Function unknown]; Region: COG1565
658172001261	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
658172001262	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
658172001263	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
658172001264	active site
658172001265	Uncharacterized conserved small protein [Function unknown]; Region: COG5508
658172001266	Protein of unknown function (DUF1674); Region: DUF1674; pfam07896
658172001267	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
658172001268	putative RNA binding site [nucleotide binding]; other site
658172001269	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
658172001270	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
658172001271	S-adenosylmethionine binding site [chemical binding]; other site
658172001272	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
658172001273	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
658172001274	purine monophosphate binding site [chemical binding]; other site
658172001275	dimer interface [polypeptide binding]; other site
658172001276	putative catalytic residues [active]
658172001277	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
658172001278	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
658172001279	active site clefts [active]
658172001280	zinc binding site [ion binding]; other site
658172001281	dimer interface [polypeptide binding]; other site
658172001282	Bacterial NAD-glutamate dehydrogenase; Region: Bac_GDH; pfam05088
658172001283	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; smart00839
658172001284	exonuclease I; Provisional; Region: sbcB; PRK11779
658172001285	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
658172001286	active site
658172001287	catalytic site [active]
658172001288	substrate binding site [chemical binding]; other site
658172001289	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
658172001290	hypothetical protein; Validated; Region: PRK00110
658172001291	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
658172001292	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
658172001293	putative active site [active]
658172001294	metal binding site [ion binding]; metal-binding site
658172001295	homodimer binding site [polypeptide binding]; other site
658172001296	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
658172001297	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
658172001298	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
658172001299	TPP-binding site [chemical binding]; other site
658172001300	dimer interface [polypeptide binding]; other site
658172001301	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
658172001302	PYR/PP interface [polypeptide binding]; other site
658172001303	dimer interface [polypeptide binding]; other site
658172001304	TPP binding site [chemical binding]; other site
658172001305	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
658172001306	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
658172001307	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
658172001308	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
658172001309	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
658172001310	Phosphoglycerate kinase; Region: PGK; pfam00162
658172001311	substrate binding site [chemical binding]; other site
658172001312	hinge regions; other site
658172001313	ADP binding site [chemical binding]; other site
658172001314	catalytic site [active]
658172001315	Class I aldolases; Region: Aldolase_Class_I; cl17187
658172001316	catalytic residue [active]
658172001317	Protein of unknown function (DUF1465); Region: DUF1465; cl11562
658172001318	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
658172001319	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
658172001320	active site
658172001321	(T/H)XGH motif; other site
658172001322	GTPase CgtA; Reviewed; Region: obgE; PRK12299
658172001323	GTP1/OBG; Region: GTP1_OBG; pfam01018
658172001324	Obg GTPase; Region: Obg; cd01898
658172001325	G1 box; other site
658172001326	GTP/Mg2+ binding site [chemical binding]; other site
658172001327	Switch I region; other site
658172001328	G2 box; other site
658172001329	G3 box; other site
658172001330	Switch II region; other site
658172001331	G4 box; other site
658172001332	G5 box; other site
658172001333	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
658172001334	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
658172001335	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
658172001336	chaperone protein DnaJ; Provisional; Region: PRK10767
658172001337	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
658172001338	HSP70 interaction site [polypeptide binding]; other site
658172001339	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
658172001340	substrate binding site [polypeptide binding]; other site
658172001341	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
658172001342	Zn binding sites [ion binding]; other site
658172001343	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
658172001344	dimer interface [polypeptide binding]; other site
658172001345	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
658172001346	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
658172001347	nucleotide binding site [chemical binding]; other site
658172001348	NEF interaction site [polypeptide binding]; other site
658172001349	SBD interface [polypeptide binding]; other site
658172001350	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
658172001351	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
658172001352	catalytic site [active]
658172001353	putative active site [active]
658172001354	putative substrate binding site [chemical binding]; other site
658172001355	Imelysin; Region: Peptidase_M75; cl09159
658172001356	Disulfide bond formation protein DsbB; Region: DsbB; pfam02600
658172001357	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
658172001358	active site
658172001359	tetramer interface; other site
658172001360	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
658172001361	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
658172001362	FAD binding pocket [chemical binding]; other site
658172001363	FAD binding motif [chemical binding]; other site
658172001364	phosphate binding motif [ion binding]; other site
658172001365	beta-alpha-beta structure motif; other site
658172001366	NAD binding pocket [chemical binding]; other site
658172001367	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
658172001368	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
658172001369	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
658172001370	UbiA prenyltransferase family; Region: UbiA; pfam01040
658172001371	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
658172001372	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
658172001373	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
658172001374	nucleoside/Zn binding site; other site
658172001375	dimer interface [polypeptide binding]; other site
658172001376	catalytic motif [active]
658172001377	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
658172001378	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
658172001379	RNA binding surface [nucleotide binding]; other site
658172001380	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
658172001381	active site
658172001382	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
658172001383	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
658172001384	S-adenosylmethionine binding site [chemical binding]; other site
658172001385	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
658172001386	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
658172001387	active site
658172001388	Domain of unknown function (DUF4170); Region: DUF4170; pfam13773
658172001389	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
658172001390	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
658172001391	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
658172001392	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
658172001393	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3908
658172001394	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
658172001395	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
658172001396	ATP binding site [chemical binding]; other site
658172001397	Mg2+ binding site [ion binding]; other site
658172001398	G-X-G motif; other site
658172001399	DNA mismatch repair protein, C-terminal domain; Region: DNA_mis_repair; pfam01119
658172001400	ATP binding site [chemical binding]; other site
658172001401	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
658172001402	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
658172001403	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
658172001404	S-adenosylmethionine binding site [chemical binding]; other site
658172001405	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK05312
658172001406	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
658172001407	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
658172001408	Organic solvent tolerance protein; Region: OstA_C; pfam04453
658172001409	Predicted permeases [General function prediction only]; Region: COG0795
658172001410	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
658172001411	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
658172001412	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
658172001413	multifunctional aminopeptidase A; Provisional; Region: PRK00913
658172001414	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
658172001415	interface (dimer of trimers) [polypeptide binding]; other site
658172001416	Substrate-binding/catalytic site; other site
658172001417	Zn-binding sites [ion binding]; other site
658172001418	DNA polymerase III chi subunit, HolC; Region: DNA_pol3_chi; pfam04364
658172001419	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
658172001420	active site
658172001421	multimer interface [polypeptide binding]; other site
658172001422	Putative Flp pilus-assembly TadE/G-like; Region: Tad; pfam13400
658172001423	von Willebrand factor (vWF) type A domain; Region: VWA; smart00327
658172001424	metal ion-dependent adhesion site (MIDAS); other site
658172001425	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
658172001426	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
658172001427	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
658172001428	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
658172001429	HlyD family secretion protein; Region: HlyD_3; pfam13437
658172001430	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
658172001431	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
658172001432	Walker A/P-loop; other site
658172001433	ATP binding site [chemical binding]; other site
658172001434	Q-loop/lid; other site
658172001435	ABC transporter signature motif; other site
658172001436	Walker B; other site
658172001437	D-loop; other site
658172001438	H-loop/switch region; other site
658172001439	Zinc-dependent metalloprotease, serralysin_like subfamily. Serralysins and related proteases are important virulence factors in pathogenic bacteria. They may be secreted into the medium via a mechanism found in gram-negative bacteria, that does not...; Region: ZnMc_serralysin_like; cd04277
658172001440	active site
658172001441	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
658172001442	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
658172001443	endonuclease III; Region: ENDO3c; smart00478
658172001444	minor groove reading motif; other site
658172001445	helix-hairpin-helix signature motif; other site
658172001446	substrate binding pocket [chemical binding]; other site
658172001447	active site
658172001448	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
658172001449	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
658172001450	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
658172001451	ATP binding site [chemical binding]; other site
658172001452	Mg++ binding site [ion binding]; other site
658172001453	motif III; other site
658172001454	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
658172001455	nucleotide binding region [chemical binding]; other site
658172001456	ATP-binding site [chemical binding]; other site
658172001457	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
658172001458	Peptidase family M23; Region: Peptidase_M23; pfam01551
658172001459	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
658172001460	seryl-tRNA synthetase; Provisional; Region: PRK05431
658172001461	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
658172001462	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
658172001463	dimer interface [polypeptide binding]; other site
658172001464	active site
658172001465	motif 1; other site
658172001466	motif 2; other site
658172001467	motif 3; other site
658172001468	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
658172001469	putative coenzyme Q binding site [chemical binding]; other site
658172001470	lipoyl synthase; Provisional; Region: PRK05481
658172001471	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
658172001472	FeS/SAM binding site; other site
658172001473	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
658172001474	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
658172001475	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
658172001476	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
658172001477	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
658172001478	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
658172001479	E3 interaction surface; other site
658172001480	lipoyl attachment site [posttranslational modification]; other site
658172001481	e3 binding domain; Region: E3_binding; pfam02817
658172001482	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
658172001483	pyruvate dehydrogenase subunit beta; Provisional; Region: PRK11892
658172001484	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
658172001485	E3 interaction surface; other site
658172001486	lipoyl attachment site [posttranslational modification]; other site
658172001487	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
658172001488	alpha subunit interface [polypeptide binding]; other site
658172001489	TPP binding site [chemical binding]; other site
658172001490	heterodimer interface [polypeptide binding]; other site
658172001491	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
658172001492	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
658172001493	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
658172001494	tetramer interface [polypeptide binding]; other site
658172001495	TPP-binding site [chemical binding]; other site
658172001496	heterodimer interface [polypeptide binding]; other site
658172001497	phosphorylation loop region [posttranslational modification]
658172001498	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
658172001499	Septum formation initiator; Region: DivIC; cl17659
658172001500	enolase; Provisional; Region: eno; PRK00077
658172001501	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
658172001502	dimer interface [polypeptide binding]; other site
658172001503	metal binding site [ion binding]; metal-binding site
658172001504	substrate binding pocket [chemical binding]; other site
658172001505	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
658172001506	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
658172001507	LexA repressor; Validated; Region: PRK00215
658172001508	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
658172001509	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
658172001510	Catalytic site [active]
658172001511	potential frameshift: common BLAST hit: gi|150396364|ref|YP_001326831.1| ComEC/Rec2-related protein
658172001512	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
658172001513	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
658172001514	dimer interface [polypeptide binding]; other site
658172001515	active site
658172001516	citrylCoA binding site [chemical binding]; other site
658172001517	NADH binding [chemical binding]; other site
658172001518	cationic pore residues; other site
658172001519	oxalacetate/citrate binding site [chemical binding]; other site
658172001520	coenzyme A binding site [chemical binding]; other site
658172001521	catalytic triad [active]
658172001522	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
658172001523	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
658172001524	CAP-like domain; other site
658172001525	active site
658172001526	primary dimer interface [polypeptide binding]; other site
658172001527	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
658172001528	dimer interface [polypeptide binding]; other site
658172001529	allosteric magnesium binding site [ion binding]; other site
658172001530	active site
658172001531	aspartate-rich active site metal binding site; other site
658172001532	Schiff base residues; other site
658172001533	Transcriptional regulators [Transcription]; Region: MarR; COG1846
658172001534	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
658172001535	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2989
658172001536	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
658172001537	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
658172001538	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
658172001539	dimer interface [polypeptide binding]; other site
658172001540	active site
658172001541	glycine-pyridoxal phosphate binding site [chemical binding]; other site
658172001542	folate binding site [chemical binding]; other site
658172001543	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
658172001544	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
658172001545	catalytic motif [active]
658172001546	Zn binding site [ion binding]; other site
658172001547	RibD C-terminal domain; Region: RibD_C; cl17279
658172001548	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
658172001549	Lumazine binding domain; Region: Lum_binding; pfam00677
658172001550	Lumazine binding domain; Region: Lum_binding; pfam00677
658172001551	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
658172001552	homopentamer interface [polypeptide binding]; other site
658172001553	active site
658172001554	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
658172001555	putative RNA binding site [nucleotide binding]; other site
658172001556	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
658172001557	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
658172001558	Cation efflux family; Region: Cation_efflux; pfam01545
658172001559	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113
658172001560	choline ABC transporter, periplasmic binding protein; Region: ABC_choline_bnd; TIGR03414
658172001561	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
658172001562	dimer interface [polypeptide binding]; other site
658172001563	conserved gate region; other site
658172001564	putative PBP binding loops; other site
658172001565	ABC-ATPase subunit interface; other site
658172001566	choline ABC transporter, ATP-binding protein; Region: ABC_choXWV_ATP; TIGR03415
658172001567	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
658172001568	Walker A/P-loop; other site
658172001569	ATP binding site [chemical binding]; other site
658172001570	Q-loop/lid; other site
658172001571	ABC transporter signature motif; other site
658172001572	Walker B; other site
658172001573	D-loop; other site
658172001574	H-loop/switch region; other site
658172001575	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
658172001576	classical (c) SDRs; Region: SDR_c; cd05233
658172001577	NAD(P) binding site [chemical binding]; other site
658172001578	active site
658172001579	amidophosphoribosyltransferase; Provisional; Region: PRK09123
658172001580	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
658172001581	active site
658172001582	tetramer interface [polypeptide binding]; other site
658172001583	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
658172001584	active site
658172001585	Colicin V production protein; Region: Colicin_V; pfam02674
658172001586	DNA repair protein RadA; Provisional; Region: PRK11823
658172001587	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
658172001588	Walker A motif; other site
658172001589	ATP binding site [chemical binding]; other site
658172001590	Walker B motif; other site
658172001591	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
658172001592	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
658172001593	active site
658172001594	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
658172001595	dimer interface [polypeptide binding]; other site
658172001596	substrate binding site [chemical binding]; other site
658172001597	catalytic residues [active]
658172001598	replicative DNA helicase; Provisional; Region: PRK09165
658172001599	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
658172001600	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
658172001601	Walker A motif; other site
658172001602	ATP binding site [chemical binding]; other site
658172001603	Walker B motif; other site
658172001604	DNA binding loops [nucleotide binding]
658172001605	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
658172001606	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
658172001607	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
658172001608	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
658172001609	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
658172001610	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
658172001611	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
658172001612	NAD binding site [chemical binding]; other site
658172001613	homodimer interface [polypeptide binding]; other site
658172001614	active site
658172001615	substrate binding site [chemical binding]; other site
658172001616	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
658172001617	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
658172001618	SEC-C motif; Region: SEC-C; pfam02810
658172001619	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
658172001620	heterotetramer interface [polypeptide binding]; other site
658172001621	active site pocket [active]
658172001622	cleavage site
658172001623	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
658172001624	active site
658172001625	8-oxo-dGMP binding site [chemical binding]; other site
658172001626	nudix motif; other site
658172001627	metal binding site [ion binding]; metal-binding site
658172001628	TLC ATP/ADP transporter; Region: TLC; pfam03219
658172001629	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
658172001630	GTP-binding protein LepA; Provisional; Region: PRK05433
658172001631	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
658172001632	G1 box; other site
658172001633	putative GEF interaction site [polypeptide binding]; other site
658172001634	GTP/Mg2+ binding site [chemical binding]; other site
658172001635	Switch I region; other site
658172001636	G2 box; other site
658172001637	G3 box; other site
658172001638	Switch II region; other site
658172001639	G4 box; other site
658172001640	G5 box; other site
658172001641	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
658172001642	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
658172001643	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
658172001644	translation initiation factor IF-3; Region: infC; TIGR00168
658172001645	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
658172001646	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
658172001647	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
658172001648	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
658172001649	23S rRNA binding site [nucleotide binding]; other site
658172001650	L21 binding site [polypeptide binding]; other site
658172001651	L13 binding site [polypeptide binding]; other site
658172001652	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
658172001653	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
658172001654	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
658172001655	dimer interface [polypeptide binding]; other site
658172001656	motif 1; other site
658172001657	active site
658172001658	motif 2; other site
658172001659	motif 3; other site
658172001660	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
658172001661	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
658172001662	putative tRNA-binding site [nucleotide binding]; other site
658172001663	B3/4 domain; Region: B3_4; pfam03483
658172001664	tRNA synthetase B5 domain; Region: B5; smart00874
658172001665	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
658172001666	dimer interface [polypeptide binding]; other site
658172001667	motif 1; other site
658172001668	motif 3; other site
658172001669	motif 2; other site
658172001670	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; smart00896
658172001671	Porin subfamily; Region: Porin_2; pfam02530
658172001672	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
658172001673	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
658172001674	S-adenosylmethionine binding site [chemical binding]; other site
658172001675	Response regulator receiver domain; Region: Response_reg; pfam00072
658172001676	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
658172001677	active site
658172001678	phosphorylation site [posttranslational modification]
658172001679	intermolecular recognition site; other site
658172001680	dimerization interface [polypeptide binding]; other site
658172001681	Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; Region: PRX5_like; cd03013
658172001682	catalytic triad [active]
658172001683	dimer interface [polypeptide binding]; other site
658172001684	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
658172001685	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
658172001686	active site
658172001687	Transglycosylase SLT domain; Region: SLT_2; pfam13406
658172001688	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
658172001689	N-acetyl-D-glucosamine binding site [chemical binding]; other site
658172001690	catalytic residue [active]
658172001691	Transglycosylase SLT domain; Region: SLT_2; pfam13406
658172001692	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
658172001693	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
658172001694	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
658172001695	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
658172001696	active site
658172001697	interdomain interaction site; other site
658172001698	putative metal-binding site [ion binding]; other site
658172001699	nucleotide binding site [chemical binding]; other site
658172001700	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
658172001701	domain I; other site
658172001702	DNA binding groove [nucleotide binding]
658172001703	phosphate binding site [ion binding]; other site
658172001704	domain II; other site
658172001705	domain III; other site
658172001706	nucleotide binding site [chemical binding]; other site
658172001707	catalytic site [active]
658172001708	domain IV; other site
658172001709	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
658172001710	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
658172001711	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
658172001712	DNA protecting protein DprA; Region: dprA; TIGR00732
658172001713	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
658172001714	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
658172001715	dihydroorotase; Validated; Region: PRK09059
658172001716	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
658172001717	active site
658172001718	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
658172001719	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
658172001720	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
658172001721	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
658172001722	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
658172001723	active site
658172001724	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
658172001725	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
658172001726	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
658172001727	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
658172001728	ligand binding site [chemical binding]; other site
658172001729	chemotaxis protein; Reviewed; Region: PRK12798
658172001730	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
658172001731	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
658172001732	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
658172001733	DNA binding site [nucleotide binding]
658172001734	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
658172001735	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
658172001736	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
658172001737	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
658172001738	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07521
658172001739	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK06008
658172001740	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
658172001741	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
658172001742	Flagellar protein FlaF; Region: FlaF; cl11454
658172001743	flagellar biosynthesis regulatory protein FlaF; Reviewed; Region: flaF; PRK12793
658172001744	Flagellar protein FlbT; Region: FlbT; cl11455
658172001745	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06009
658172001746	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
658172001747	flagellar biosynthesis protein FliQ; Reviewed; Region: fliQ; PRK06010
658172001748	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; cl07980
658172001749	FHIPEP family; Region: FHIPEP; pfam00771
658172001750	Bacterial export proteins, family 1; Region: Bac_export_1; cl00734
658172001751	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14188
658172001752	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
658172001753	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
658172001754	homodimer interface [polypeptide binding]; other site
658172001755	NADP binding site [chemical binding]; other site
658172001756	substrate binding site [chemical binding]; other site
658172001757	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
658172001758	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
658172001759	putative active site [active]
658172001760	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
658172001761	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
658172001762	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
658172001763	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
658172001764	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
658172001765	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
658172001766	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
658172001767	dimer interface [polypeptide binding]; other site
658172001768	putative radical transfer pathway; other site
658172001769	diiron center [ion binding]; other site
658172001770	tyrosyl radical; other site
658172001771	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
658172001772	Reovirus sigma C capsid protein; Region: Reo_sigmaC; pfam04582
658172001773	structural protein; Region: PHA01972
658172001774	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
658172001775	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07207
658172001776	ATP cone domain; Region: ATP-cone; pfam03477
658172001777	Class I ribonucleotide reductase; Region: RNR_I; cd01679
658172001778	active site
658172001779	dimer interface [polypeptide binding]; other site
658172001780	catalytic residues [active]
658172001781	effector binding site; other site
658172001782	R2 peptide binding site; other site
658172001783	SmpA / OmlA family; Region: SmpA_OmlA; cl17115
658172001784	putative phosphate acyltransferase; Provisional; Region: PRK05331
658172001785	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
658172001786	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
658172001787	dimer interface [polypeptide binding]; other site
658172001788	active site
658172001789	CoA binding pocket [chemical binding]; other site
658172001790	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
658172001791	IHF dimer interface [polypeptide binding]; other site
658172001792	IHF - DNA interface [nucleotide binding]; other site
658172001793	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
658172001794	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
658172001795	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
658172001796	Cation efflux family; Region: Cation_efflux; cl00316
658172001797	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
658172001798	catalytic residue [active]
658172001799	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
658172001800	ATP binding site [chemical binding]; other site
658172001801	active site
658172001802	substrate binding site [chemical binding]; other site
658172001803	Domain of unknown function DUF59; Region: DUF59; pfam01883
658172001804	cell division ATPase MinD, archaeal; Region: minD_arch; TIGR01969
658172001805	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
658172001806	Walker A motif; other site
658172001807	K+ transporter [Inorganic ion transport and metabolism]; Region: Kup; COG3158
658172001808	hypothetical protein; Provisional; Region: PRK14013
658172001809	pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated; Region: PRK06555
658172001810	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases; Region: PFK; cl00204
658172001811	active site
658172001812	ADP/pyrophosphate binding site [chemical binding]; other site
658172001813	allosteric effector site; other site
658172001814	fructose-1,6-bisphosphate binding site; other site
658172001815	GTP-binding protein YchF; Reviewed; Region: PRK09601
658172001816	YchF GTPase; Region: YchF; cd01900
658172001817	G1 box; other site
658172001818	GTP/Mg2+ binding site [chemical binding]; other site
658172001819	Switch I region; other site
658172001820	G2 box; other site
658172001821	Switch II region; other site
658172001822	G3 box; other site
658172001823	G4 box; other site
658172001824	G5 box; other site
658172001825	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
658172001826	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
658172001827	putative active site [active]
658172001828	catalytic residue [active]
658172001829	Uncharacterized protein conserved in bacteria (DUF2336); Region: DUF2336; pfam10098
658172001830	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
658172001831	Domain of unknown function DUF20; Region: UPF0118; pfam01594
658172001832	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
658172001833	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
658172001834	ATP binding site [chemical binding]; other site
658172001835	Mg2+ binding site [ion binding]; other site
658172001836	G-X-G motif; other site
658172001837	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
658172001838	anchoring element; other site
658172001839	dimer interface [polypeptide binding]; other site
658172001840	ATP binding site [chemical binding]; other site
658172001841	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
658172001842	active site
658172001843	metal binding site [ion binding]; metal-binding site
658172001844	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
658172001845	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
658172001846	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
658172001847	TMP-binding site; other site
658172001848	ATP-binding site [chemical binding]; other site
658172001849	DNA polymerase III subunit delta'; Validated; Region: PRK09112
658172001850	DNA polymerase III subunit delta'; Validated; Region: PRK08485
658172001851	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
658172001852	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
658172001853	active site
658172001854	HIGH motif; other site
658172001855	KMSKS motif; other site
658172001856	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
658172001857	tRNA binding surface [nucleotide binding]; other site
658172001858	anticodon binding site; other site
658172001859	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
658172001860	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
658172001861	active site
658172001862	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
658172001863	putative hydrolase; Provisional; Region: PRK02113
658172001864	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
658172001865	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
658172001866	metal ion-dependent adhesion site (MIDAS); other site
658172001867	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
658172001868	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
658172001869	Uncharacterized conserved protein [Function unknown]; Region: COG1432
658172001870	LabA_like proteins; Region: LabA; cd10911
658172001871	putative metal binding site [ion binding]; other site
658172001872	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
658172001873	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
658172001874	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
658172001875	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
658172001876	Catalytic site [active]
658172001877	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
658172001878	ribonuclease III; Reviewed; Region: PRK12371
658172001879	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
658172001880	dimerization interface [polypeptide binding]; other site
658172001881	active site
658172001882	metal binding site [ion binding]; metal-binding site
658172001883	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
658172001884	dsRNA binding site [nucleotide binding]; other site
658172001885	GTPase Era; Reviewed; Region: era; PRK00089
658172001886	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
658172001887	G1 box; other site
658172001888	GTP/Mg2+ binding site [chemical binding]; other site
658172001889	Switch I region; other site
658172001890	G2 box; other site
658172001891	Switch II region; other site
658172001892	G3 box; other site
658172001893	G4 box; other site
658172001894	G5 box; other site
658172001895	KH domain; Region: KH_2; pfam07650
658172001896	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14353
658172001897	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
658172001898	Substrate binding site; other site
658172001899	Mg++ binding site; other site
658172001900	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
658172001901	active site
658172001902	substrate binding site [chemical binding]; other site
658172001903	CoA binding site [chemical binding]; other site
658172001904	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
658172001905	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
658172001906	glutaminase active site [active]
658172001907	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
658172001908	dimer interface [polypeptide binding]; other site
658172001909	active site
658172001910	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
658172001911	dimer interface [polypeptide binding]; other site
658172001912	active site
658172001913	Uncharacterized conserved protein [Function unknown]; Region: COG2928
658172001914	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
658172001915	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
658172001916	generic binding surface II; other site
658172001917	ssDNA binding site; other site
658172001918	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
658172001919	ATP binding site [chemical binding]; other site
658172001920	putative Mg++ binding site [ion binding]; other site
658172001921	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
658172001922	nucleotide binding region [chemical binding]; other site
658172001923	ATP-binding site [chemical binding]; other site
658172001924	Flavinator of succinate dehydrogenase; Region: Sdh5; cl01110
658172001925	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
658172001926	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
658172001927	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
658172001928	ATP binding site [chemical binding]; other site
658172001929	putative Mg++ binding site [ion binding]; other site
658172001930	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
658172001931	nucleotide binding region [chemical binding]; other site
658172001932	ATP-binding site [chemical binding]; other site
658172001933	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
658172001934	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
658172001935	Recombination protein O N terminal; Region: RecO_N; pfam11967
658172001936	Recombination protein O C terminal; Region: RecO_C; pfam02565
658172001937	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
658172001938	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
658172001939	active site
658172001940	HIGH motif; other site
658172001941	dimer interface [polypeptide binding]; other site
658172001942	KMSKS motif; other site
658172001943	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
658172001944	RNA binding surface [nucleotide binding]; other site
658172001945	YecR-like lipoprotein; Region: YecR; cl10256
658172001946	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
658172001947	Ligand Binding Site [chemical binding]; other site
658172001948	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
658172001949	active site
658172001950	Uncharacterized membrane-bound protein [Function unknown]; Region: COG3898
658172001951	HemY protein N-terminus; Region: HemY_N; pfam07219
658172001952	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
658172001953	binding surface
658172001954	TPR motif; other site
658172001955	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4223
658172001956	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
658172001957	active site
658172001958	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
658172001959	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
658172001960	domain interfaces; other site
658172001961	active site
658172001962	UGMP family protein; Validated; Region: PRK09604
658172001963	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
658172001964	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
658172001965	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
658172001966	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
658172001967	EVE domain; Region: EVE; cl00728
658172001968	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
658172001969	Iron-sulfur protein interface; other site
658172001970	proximal quinone binding site [chemical binding]; other site
658172001971	SdhD (CybS) interface [polypeptide binding]; other site
658172001972	proximal heme binding site [chemical binding]; other site
658172001973	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit-like; composed of predominantly uncharacterized bacterial proteins with similarity to the E. coli SdhD subunit. One characterized protein is the respiratory...; Region: SQR_TypeC_SdhD_like; cd03495
658172001974	putative SdhC subunit interface [polypeptide binding]; other site
658172001975	putative proximal heme binding site [chemical binding]; other site
658172001976	putative Iron-sulfur protein interface [polypeptide binding]; other site
658172001977	putative proximal quinone binding site; other site
658172001978	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK09078
658172001979	L-aspartate oxidase; Provisional; Region: PRK06175
658172001980	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
658172001981	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
658172001982	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
658172001983	Protease inhibitor Inh; Region: Inh; pfam02974
658172001984	Predicted ATPase [General function prediction only]; Region: COG1485
658172001985	malate dehydrogenase; Reviewed; Region: PRK06223
658172001986	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
658172001987	NAD(P) binding site [chemical binding]; other site
658172001988	dimer interface [polypeptide binding]; other site
658172001989	tetramer (dimer of dimers) interface [polypeptide binding]; other site
658172001990	substrate binding site [chemical binding]; other site
658172001991	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
658172001992	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
658172001993	CoA-ligase; Region: Ligase_CoA; pfam00549
658172001994	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
658172001995	CoA binding domain; Region: CoA_binding; smart00881
658172001996	Predicted kinase [General function prediction only]; Region: COG4857; cl17281
658172001997	CoA-ligase; Region: Ligase_CoA; pfam00549
658172001998	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
658172001999	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
658172002000	TPP-binding site [chemical binding]; other site
658172002001	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
658172002002	dimer interface [polypeptide binding]; other site
658172002003	PYR/PP interface [polypeptide binding]; other site
658172002004	TPP binding site [chemical binding]; other site
658172002005	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
658172002006	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
658172002007	E3 interaction surface; other site
658172002008	lipoyl attachment site [posttranslational modification]; other site
658172002009	e3 binding domain; Region: E3_binding; pfam02817
658172002010	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
658172002011	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
658172002012	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
658172002013	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
658172002014	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
658172002015	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
658172002016	tetramer (dimer of dimers) interface [polypeptide binding]; other site
658172002017	active site
658172002018	dimer interface [polypeptide binding]; other site
658172002019	glutathione reductase; Validated; Region: PRK06116
658172002020	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
658172002021	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
658172002022	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
658172002023	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
658172002024	putative ABC transporter; Region: ycf24; CHL00085
658172002025	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
658172002026	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
658172002027	Walker A/P-loop; other site
658172002028	ATP binding site [chemical binding]; other site
658172002029	Q-loop/lid; other site
658172002030	ABC transporter signature motif; other site
658172002031	Walker B; other site
658172002032	D-loop; other site
658172002033	H-loop/switch region; other site
658172002034	FeS assembly protein SufD; Region: sufD; TIGR01981
658172002035	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
658172002036	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
658172002037	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
658172002038	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
658172002039	catalytic residue [active]
658172002040	FeS assembly SUF system protein; Region: SUF_assoc; TIGR02945
658172002041	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
658172002042	Fe-S metabolism associated domain; Region: SufE; cl00951
658172002043	NAD synthetase; Provisional; Region: PRK13981
658172002044	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
658172002045	multimer interface [polypeptide binding]; other site
658172002046	active site
658172002047	catalytic triad [active]
658172002048	protein interface 1 [polypeptide binding]; other site
658172002049	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
658172002050	homodimer interface [polypeptide binding]; other site
658172002051	NAD binding pocket [chemical binding]; other site
658172002052	ATP binding pocket [chemical binding]; other site
658172002053	Mg binding site [ion binding]; other site
658172002054	active-site loop [active]
658172002055	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
658172002056	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
658172002057	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
658172002058	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
658172002059	active site
658172002060	dimer interface [polypeptide binding]; other site
658172002061	motif 1; other site
658172002062	motif 2; other site
658172002063	motif 3; other site
658172002064	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
658172002065	anticodon binding site; other site
658172002066	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
658172002067	DNA-binding site [nucleotide binding]; DNA binding site
658172002068	RNA-binding motif; other site
658172002069	cell division protein MraZ; Reviewed; Region: PRK00326
658172002070	MraZ protein; Region: MraZ; pfam02381
658172002071	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
658172002072	MraW methylase family; Region: Methyltransf_5; cl17771
658172002073	Predicted secreted (periplasmic) protein [Function unknown]; Region: COG5462
658172002074	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
658172002075	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
658172002076	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
658172002077	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
658172002078	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
658172002079	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
658172002080	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
658172002081	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Provisional; Region: PRK14093
658172002082	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
658172002083	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
658172002084	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
658172002085	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
658172002086	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
658172002087	Mg++ binding site [ion binding]; other site
658172002088	putative catalytic motif [active]
658172002089	putative substrate binding site [chemical binding]; other site
658172002090	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01390
658172002091	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
658172002092	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
658172002093	cell division protein FtsW; Region: ftsW; TIGR02614
658172002094	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
658172002095	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
658172002096	active site
658172002097	homodimer interface [polypeptide binding]; other site
658172002098	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
658172002099	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
658172002100	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
658172002101	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
658172002102	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
658172002103	FAD binding domain; Region: FAD_binding_4; pfam01565
658172002104	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
658172002105	hypothetical protein; Region: PHA00661
658172002106	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
658172002107	DALR anticodon binding domain; Region: DALR_1; pfam05746
658172002108	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
658172002109	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
658172002110	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
658172002111	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
658172002112	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
658172002113	catalytic residue [active]
658172002114	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
658172002115	ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Region: ATP_synt_6_or_A; TIGR01131
658172002116	F0F1 ATP synthase subunit C; Validated; Region: PRK07558
658172002117	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
658172002118	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
658172002119	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
658172002120	hypothetical protein; Provisional; Region: PRK13694
658172002121	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
658172002122	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
658172002123	metal binding site [ion binding]; metal-binding site
658172002124	active site
658172002125	I-site; other site
658172002126	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
658172002127	RNA/DNA hybrid binding site [nucleotide binding]; other site
658172002128	active site
658172002129	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
658172002130	ligand binding site [chemical binding]; other site
658172002131	active site
658172002132	UGI interface [polypeptide binding]; other site
658172002133	catalytic site [active]
658172002134	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
658172002135	Coproporphyrinogen III oxidase [Coenzyme metabolism]; Region: HemF; COG0408
658172002136	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; cl17752
658172002137	phosphoglucomutase; Region: PLN02307
658172002138	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
658172002139	active site
658172002140	substrate binding site [chemical binding]; other site
658172002141	metal binding site [ion binding]; metal-binding site
658172002142	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
658172002143	metal ion-dependent adhesion site (MIDAS); other site
658172002144	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
658172002145	metal ion-dependent adhesion site (MIDAS); other site
658172002146	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
658172002147	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
658172002148	substrate binding pocket [chemical binding]; other site
658172002149	chain length determination region; other site
658172002150	substrate-Mg2+ binding site; other site
658172002151	catalytic residues [active]
658172002152	aspartate-rich region 1; other site
658172002153	active site lid residues [active]
658172002154	aspartate-rich region 2; other site
658172002155	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
658172002156	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
658172002157	substrate binding pocket [chemical binding]; other site
658172002158	membrane-bound complex binding site; other site
658172002159	hinge residues; other site
658172002160	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
658172002161	dimer interface [polypeptide binding]; other site
658172002162	conserved gate region; other site
658172002163	putative PBP binding loops; other site
658172002164	ABC-ATPase subunit interface; other site
658172002165	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
658172002166	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
658172002167	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
658172002168	excinuclease ABC subunit B; Provisional; Region: PRK05298
658172002169	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
658172002170	ATP binding site [chemical binding]; other site
658172002171	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
658172002172	nucleotide binding region [chemical binding]; other site
658172002173	ATP-binding site [chemical binding]; other site
658172002174	Ultra-violet resistance protein B; Region: UvrB; pfam12344
658172002175	UvrB/uvrC motif; Region: UVR; pfam02151
658172002176	Protein of unknown function (DUF1217); Region: DUF1217; pfam06748
658172002177	Protein of unknown function (DUF1217); Region: DUF1217; pfam06748
658172002178	Protein of unknown function (DUF1217); Region: DUF1217; pfam06748
658172002179	Protein of unknown function (DUF1217); Region: DUF1217; pfam06748
658172002180	Helix-turn-helix domain; Region: HTH_19; pfam12844
658172002181	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
658172002182	non-specific DNA binding site [nucleotide binding]; other site
658172002183	salt bridge; other site
658172002184	sequence-specific DNA binding site [nucleotide binding]; other site
658172002185	Protein of unknown function (DUF1640); Region: DUF1640; pfam07798
658172002186	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
658172002187	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
658172002188	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
658172002189	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
658172002190	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
658172002191	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
658172002192	motif II; other site
658172002193	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
658172002194	catalytic residues [active]
658172002195	HflC protein; Region: hflC; TIGR01932
658172002196	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
658172002197	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
658172002198	HflK protein; Region: hflK; TIGR01933
658172002199	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
658172002200	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
658172002201	folate binding site [chemical binding]; other site
658172002202	NADP+ binding site [chemical binding]; other site
658172002203	thymidylate synthase; Reviewed; Region: thyA; PRK01827
658172002204	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
658172002205	dimerization interface [polypeptide binding]; other site
658172002206	active site
658172002207	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3814
658172002208	AsmA family; Region: AsmA; pfam05170
658172002209	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
658172002210	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
658172002211	ligand binding site [chemical binding]; other site
658172002212	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
658172002213	Part of AAA domain; Region: AAA_19; pfam13245
658172002214	Family description; Region: UvrD_C_2; pfam13538
658172002215	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; cl00868
658172002216	Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase; cl00205
658172002217	homodimer interface [polypeptide binding]; other site
658172002218	substrate binding pocket [chemical binding]; other site
658172002219	catalytic residues [active]
658172002220	NADH/NADPH cofactor binding site [chemical binding]; other site
658172002221	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
658172002222	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
658172002223	homotetramer interface [polypeptide binding]; other site
658172002224	FMN binding site [chemical binding]; other site
658172002225	homodimer contacts [polypeptide binding]; other site
658172002226	putative active site [active]
658172002227	putative substrate binding site [chemical binding]; other site
658172002228	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
658172002229	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
658172002230	dimer interface [polypeptide binding]; other site
658172002231	active site
658172002232	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
658172002233	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
658172002234	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
658172002235	Mevalonate pyrophosphate decarboxylase [Lipid metabolism]; Region: MVD1; COG3407
658172002236	diphosphomevalonate decarboxylase; Region: PLN02407
658172002237	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
658172002238	active site
658172002239	substrate binding pocket [chemical binding]; other site
658172002240	dimer interface [polypeptide binding]; other site
658172002241	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
658172002242	active site
658172002243	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
658172002244	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
658172002245	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
658172002246	GatB domain; Region: GatB_Yqey; smart00845
658172002247	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
658172002248	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
658172002249	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
658172002250	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
658172002251	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
658172002252	Terminase-like family; Region: Terminase_6; pfam03237
658172002253	Bacteriophage terminase large (ATPase) subunit and inactivated derivatives [General function prediction only]; Region: COG5565
658172002254	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
658172002255	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
658172002256	non-specific DNA binding site [nucleotide binding]; other site
658172002257	salt bridge; other site
658172002258	sequence-specific DNA binding site [nucleotide binding]; other site
658172002259	replicative DNA helicase; Region: DnaB; TIGR00665
658172002260	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
658172002261	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
658172002262	Walker A motif; other site
658172002263	ATP binding site [chemical binding]; other site
658172002264	Walker B motif; other site
658172002265	DNA binding loops [nucleotide binding]
658172002266	Protein of unknown function (DUF1376); Region: DUF1376; cl01531
658172002267	SurA N-terminal domain; Region: SurA_N_3; cl07813
658172002268	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
658172002269	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
658172002270	Gamma-glutamylcysteine synthetase [Coenzyme metabolism]; Region: GshA; COG3572
658172002271	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
658172002272	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
658172002273	Coenzyme A binding pocket [chemical binding]; other site
658172002274	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
658172002275	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
658172002276	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
658172002277	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08159
658172002278	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
658172002279	NAD binding site [chemical binding]; other site
658172002280	homotetramer interface [polypeptide binding]; other site
658172002281	homodimer interface [polypeptide binding]; other site
658172002282	substrate binding site [chemical binding]; other site
658172002283	active site
658172002284	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
658172002285	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
658172002286	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
658172002287	FMN binding site [chemical binding]; other site
658172002288	active site
658172002289	catalytic residues [active]
658172002290	substrate binding site [chemical binding]; other site
658172002291	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
658172002292	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
658172002293	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
658172002294	DNA photolyase; Region: DNA_photolyase; pfam00875
658172002295	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
658172002296	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
658172002297	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
658172002298	catalytic residues [active]
658172002299	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
658172002300	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
658172002301	nucleotide binding pocket [chemical binding]; other site
658172002302	K-X-D-G motif; other site
658172002303	catalytic site [active]
658172002304	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
658172002305	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
658172002306	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
658172002307	Dimer interface [polypeptide binding]; other site
658172002308	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
658172002309	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
658172002310	Walker A/P-loop; other site
658172002311	ATP binding site [chemical binding]; other site
658172002312	Q-loop/lid; other site
658172002313	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
658172002314	ABC transporter signature motif; other site
658172002315	Walker B; other site
658172002316	D-loop; other site
658172002317	H-loop/switch region; other site
658172002318	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
658172002319	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
658172002320	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
658172002321	Cell division GTPase [Cell division and chromosome partitioning]; Region: FtsZ; COG0206
658172002322	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
658172002323	nucleotide binding site [chemical binding]; other site
658172002324	SulA interaction site; other site
658172002325	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
658172002326	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
658172002327	Cell division protein FtsA; Region: FtsA; smart00842
658172002328	Cell division protein FtsA; Region: FtsA; pfam14450
658172002329	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
658172002330	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
658172002331	Cell division protein FtsQ; Region: FtsQ; pfam03799
658172002332	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
658172002333	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
658172002334	ATP-grasp domain; Region: ATP-grasp_4; cl17255
658172002335	Protein of unknown function (DUF4231); Region: DUF4231; pfam14015
658172002336	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
658172002337	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
658172002338	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
658172002339	non-specific DNA binding site [nucleotide binding]; other site
658172002340	salt bridge; other site
658172002341	sequence-specific DNA binding site [nucleotide binding]; other site
658172002342	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
658172002343	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
658172002344	non-specific DNA binding site [nucleotide binding]; other site
658172002345	salt bridge; other site
658172002346	sequence-specific DNA binding site [nucleotide binding]; other site
658172002347	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
658172002348	DNA binding site [nucleotide binding]
658172002349	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
658172002350	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
658172002351	active site
658172002352	NTP binding site [chemical binding]; other site
658172002353	metal binding triad [ion binding]; metal-binding site
658172002354	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
658172002355	Preprotein translocase subunit YajC [Intracellular trafficking and secretion]; Region: YajC; COG1862
658172002356	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
658172002357	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
658172002358	HIGH motif; other site
658172002359	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
658172002360	active site
658172002361	KMSKS motif; other site
658172002362	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
658172002363	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
658172002364	dimer interface [polypeptide binding]; other site
658172002365	putative anticodon binding site; other site
658172002366	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
658172002367	motif 1; other site
658172002368	active site
658172002369	motif 2; other site
658172002370	motif 3; other site
658172002371	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
658172002372	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
658172002373	FeS/SAM binding site; other site
658172002374	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
658172002375	Thiamine pyrophosphokinase; Region: TPK; cd07995
658172002376	active site
658172002377	dimerization interface [polypeptide binding]; other site
658172002378	thiamine binding site [chemical binding]; other site
658172002379	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
658172002380	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
658172002381	ABC transporter; Region: ABC_tran_2; pfam12848
658172002382	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
658172002383	elongation factor P; Validated; Region: PRK00529
658172002384	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
658172002385	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
658172002386	RNA binding site [nucleotide binding]; other site
658172002387	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
658172002388	RNA binding site [nucleotide binding]; other site
658172002389	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
658172002390	EF-P lysine aminoacylase GenX; Region: genX; TIGR00462
658172002391	motif 1; other site
658172002392	dimer interface [polypeptide binding]; other site
658172002393	active site
658172002394	motif 2; other site
658172002395	motif 3; other site
658172002396	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
658172002397	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
658172002398	FeS/SAM binding site; other site
658172002399	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
658172002400	catalytic center binding site [active]
658172002401	ATP binding site [chemical binding]; other site
658172002402	Dihydroneopterin aldolase [Coenzyme metabolism]; Region: FolB; COG1539
658172002403	active site
658172002404	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
658172002405	dihydropteroate synthase; Region: DHPS; TIGR01496
658172002406	substrate binding pocket [chemical binding]; other site
658172002407	dimer interface [polypeptide binding]; other site
658172002408	inhibitor binding site; inhibition site
658172002409	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07133
658172002410	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
658172002411	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
658172002412	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
658172002413	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
658172002414	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
658172002415	trimer interface [polypeptide binding]; other site
658172002416	active site
658172002417	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
658172002418	hydroxyglutarate oxidase; Provisional; Region: PRK11728
658172002419	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
658172002420	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
658172002421	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
658172002422	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
658172002423	substrate binding site [chemical binding]; other site
658172002424	hexamer interface [polypeptide binding]; other site
658172002425	metal binding site [ion binding]; metal-binding site
658172002426	adenylosuccinate lyase; Provisional; Region: PRK07492
658172002427	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
658172002428	tetramer interface [polypeptide binding]; other site
658172002429	active site
658172002430	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
658172002431	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
658172002432	ATP binding site [chemical binding]; other site
658172002433	active site
658172002434	substrate binding site [chemical binding]; other site
658172002435	phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed; Region: PRK05974
658172002436	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
658172002437	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
658172002438	putative active site [active]
658172002439	catalytic triad [active]
658172002440	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
658172002441	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
658172002442	dimerization interface [polypeptide binding]; other site
658172002443	ATP binding site [chemical binding]; other site
658172002444	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
658172002445	dimerization interface [polypeptide binding]; other site
658172002446	ATP binding site [chemical binding]; other site
658172002447	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
658172002448	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
658172002449	putative GSH binding site [chemical binding]; other site
658172002450	catalytic residues [active]
658172002451	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
658172002452	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
658172002453	putative substrate translocation pore; other site
658172002454	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
658172002455	glutaminase; Provisional; Region: PRK00971
658172002456	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
658172002457	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
658172002458	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
658172002459	RNA binding surface [nucleotide binding]; other site
658172002460	glutamate racemase; Provisional; Region: PRK00865
658172002461	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
658172002462	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
658172002463	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
658172002464	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
658172002465	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
658172002466	dimer interface [polypeptide binding]; other site
658172002467	phosphorylation site [posttranslational modification]
658172002468	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
658172002469	ATP binding site [chemical binding]; other site
658172002470	Mg2+ binding site [ion binding]; other site
658172002471	G-X-G motif; other site
658172002472	isocitrate dehydrogenase; Validated; Region: PRK08299
658172002473	CTP synthetase; Validated; Region: pyrG; PRK05380
658172002474	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
658172002475	Catalytic site [active]
658172002476	active site
658172002477	UTP binding site [chemical binding]; other site
658172002478	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
658172002479	active site
658172002480	putative oxyanion hole; other site
658172002481	catalytic triad [active]
658172002482	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
658172002483	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
658172002484	triosephosphate isomerase; Provisional; Region: PRK14565
658172002485	substrate binding site [chemical binding]; other site
658172002486	dimer interface [polypeptide binding]; other site
658172002487	catalytic triad [active]
658172002488	ferrochelatase; Reviewed; Region: hemH; PRK00035
658172002489	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
658172002490	C-terminal domain interface [polypeptide binding]; other site
658172002491	active site
658172002492	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
658172002493	active site
658172002494	N-terminal domain interface [polypeptide binding]; other site
658172002495	Lipopolysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: RgpF; COG3754
658172002496	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
658172002497	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
658172002498	FeS/SAM binding site; other site
658172002499	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
658172002500	UbiA prenyltransferase family; Region: UbiA; pfam01040
658172002501	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
658172002502	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
658172002503	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
658172002504	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
658172002505	hypothetical protein; Region: PHA00662
658172002506	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
658172002507	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
658172002508	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
658172002509	active site
658172002510	Int/Topo IB signature motif; other site
658172002511	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
658172002512	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
658172002513	catalytic triad [active]
658172002514	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
658172002515	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
658172002516	active site
658172002517	HIGH motif; other site
658172002518	nucleotide binding site [chemical binding]; other site
658172002519	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
658172002520	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
658172002521	active site
658172002522	KMSKS motif; other site
658172002523	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
658172002524	tRNA binding surface [nucleotide binding]; other site
658172002525	anticodon binding site; other site
658172002526	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
658172002527	Protein of unknown function (DUF2497); Region: DUF2497; pfam10691
658172002528	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
658172002529	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
658172002530	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
658172002531	dimer interface [polypeptide binding]; other site
658172002532	motif 1; other site
658172002533	active site
658172002534	motif 2; other site
658172002535	motif 3; other site
658172002536	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
658172002537	anticodon binding site; other site
658172002538	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
658172002539	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
658172002540	hinge; other site
658172002541	active site
658172002542	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK13024
658172002543	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
658172002544	Protein export membrane protein; Region: SecD_SecF; pfam02355
658172002545	putative cation:proton antiport protein; Provisional; Region: PRK10669
658172002546	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
658172002547	TrkA-N domain; Region: TrkA_N; pfam02254
658172002548	Lipopolysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: RgpF; COG3754
658172002549	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
658172002550	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
658172002551	substrate binding site; other site
658172002552	tetramer interface; other site
658172002553	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
658172002554	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
658172002555	NADP binding site [chemical binding]; other site
658172002556	active site
658172002557	putative substrate binding site [chemical binding]; other site
658172002558	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
658172002559	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
658172002560	NAD binding site [chemical binding]; other site
658172002561	substrate binding site [chemical binding]; other site
658172002562	homodimer interface [polypeptide binding]; other site
658172002563	active site
658172002564	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
658172002565	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
658172002566	Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; Region: GT2_RfbC_Mx_like; cd04184
658172002567	Probable Catalytic site; other site
658172002568	metal-binding site
658172002569	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
658172002570	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
658172002571	Probable Catalytic site; other site
658172002572	metal-binding site
658172002573	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
658172002574	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
658172002575	ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; Region: ABC_MTABC3_MDL1_MDL2; cd03249
658172002576	Walker A/P-loop; other site
658172002577	ATP binding site [chemical binding]; other site
658172002578	Q-loop/lid; other site
658172002579	ABC transporter signature motif; other site
658172002580	Walker B; other site
658172002581	D-loop; other site
658172002582	H-loop/switch region; other site
658172002583	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
658172002584	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
658172002585	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
658172002586	active site
658172002587	substrate binding site [chemical binding]; other site
658172002588	cosubstrate binding site; other site
658172002589	catalytic site [active]
658172002590	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
658172002591	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
658172002592	catalytic site [active]
658172002593	G-X2-G-X-G-K; other site
658172002594	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
658172002595	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
658172002596	active site
658172002597	phosphorylation site [posttranslational modification]
658172002598	intermolecular recognition site; other site
658172002599	dimerization interface [polypeptide binding]; other site
658172002600	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172002601	Walker A motif; other site
658172002602	ATP binding site [chemical binding]; other site
658172002603	Walker B motif; other site
658172002604	arginine finger; other site
658172002605	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
658172002606	Squalene/phytoene synthase; Region: SQS_PSY; pfam00494
658172002607	substrate binding pocket [chemical binding]; other site
658172002608	ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639
658172002609	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172002610	Walker A motif; other site
658172002611	ATP binding site [chemical binding]; other site
658172002612	Walker B motif; other site
658172002613	arginine finger; other site
658172002614	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
658172002615	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172002616	Walker A motif; other site
658172002617	ATP binding site [chemical binding]; other site
658172002618	Walker B motif; other site
658172002619	arginine finger; other site
658172002620	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
658172002621	Uncharacterized conserved protein [Function unknown]; Region: COG2127
658172002622	Protein of unknown function (DUF3126); Region: DUF3126; pfam11324
658172002623	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
658172002624	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
658172002625	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4391
658172002626	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
658172002627	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
658172002628	lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096
658172002629	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
658172002630	substrate binding pocket [chemical binding]; other site
658172002631	membrane-bound complex binding site; other site
658172002632	hinge residues; other site
658172002633	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
658172002634	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
658172002635	conserved gate region; other site
658172002636	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
658172002637	dimer interface [polypeptide binding]; other site
658172002638	ABC-ATPase subunit interface; other site
658172002639	putative PBP binding loops; other site
658172002640	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
658172002641	dimer interface [polypeptide binding]; other site
658172002642	conserved gate region; other site
658172002643	putative PBP binding loops; other site
658172002644	ABC-ATPase subunit interface; other site
658172002645	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
658172002646	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
658172002647	Walker A/P-loop; other site
658172002648	ATP binding site [chemical binding]; other site
658172002649	Q-loop/lid; other site
658172002650	ABC transporter signature motif; other site
658172002651	Walker B; other site
658172002652	D-loop; other site
658172002653	H-loop/switch region; other site
658172002654	ETC complex I subunit conserved region; Region: ETC_C1_NDUFA4; pfam04800
658172002655	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
658172002656	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
658172002657	DHH family; Region: DHH; pfam01368
658172002658	DHHA1 domain; Region: DHHA1; pfam02272
658172002659	homoserine dehydrogenase; Provisional; Region: PRK06349
658172002660	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
658172002661	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
658172002662	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
658172002663	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
658172002664	active site
658172002665	hypothetical protein; Reviewed; Region: PRK00024
658172002666	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
658172002667	MPN+ (JAMM) motif; other site
658172002668	Zinc-binding site [ion binding]; other site
658172002669	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
658172002670	trigger factor; Provisional; Region: tig; PRK01490
658172002671	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
658172002672	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
658172002673	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
658172002674	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
658172002675	TM-ABC transporter signature motif; other site
658172002676	Protein of unknown function (DUF1153); Region: DUF1153; pfam06627
658172002677	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
658172002678	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
658172002679	active site
658172002680	phosphorylation site [posttranslational modification]
658172002681	intermolecular recognition site; other site
658172002682	dimerization interface [polypeptide binding]; other site
658172002683	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
658172002684	DNA binding site [nucleotide binding]
658172002685	Response regulator receiver domain; Region: Response_reg; pfam00072
658172002686	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
658172002687	active site
658172002688	phosphorylation site [posttranslational modification]
658172002689	intermolecular recognition site; other site
658172002690	dimerization interface [polypeptide binding]; other site
658172002691	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5385
658172002692	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
658172002693	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
658172002694	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
658172002695	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
658172002696	active site
658172002697	PilZ domain; Region: PilZ; pfam07238
658172002698	PilZ domain; Region: PilZ; pfam07238
658172002699	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
658172002700	GTP cyclohydrolase I; Provisional; Region: PLN03044
658172002701	active site
658172002702	hypothetical protein; Validated; Region: PRK00041
658172002703	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
658172002704	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
658172002705	active site
658172002706	DNA binding site [nucleotide binding]
658172002707	Int/Topo IB signature motif; other site
658172002708	Domain of unknown function DUF59; Region: DUF59; pfam01883
658172002709	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
658172002710	Peptidase family M23; Region: Peptidase_M23; pfam01551
658172002711	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
658172002712	Clp amino terminal domain; Region: Clp_N; pfam02861
658172002713	Clp amino terminal domain; Region: Clp_N; pfam02861
658172002714	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172002715	Walker A motif; other site
658172002716	ATP binding site [chemical binding]; other site
658172002717	Walker B motif; other site
658172002718	arginine finger; other site
658172002719	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172002720	Walker A motif; other site
658172002721	ATP binding site [chemical binding]; other site
658172002722	Walker B motif; other site
658172002723	arginine finger; other site
658172002724	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
658172002725	Domain of unknown function (DUF4167); Region: DUF4167; pfam13763
658172002726	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
658172002727	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
658172002728	S-adenosylmethionine binding site [chemical binding]; other site
658172002729	peptide chain release factor 1; Validated; Region: prfA; PRK00591
658172002730	This domain is found in peptide chain release factors; Region: PCRF; smart00937
658172002731	RF-1 domain; Region: RF-1; pfam00472
658172002732	aspartate kinase; Reviewed; Region: PRK06635
658172002733	AAK_AK-DapG-like: Amino Acid Kinase Superfamily (AAK), AK-DapG-like; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the diaminopimelate-sensitive aspartokinase isoenzyme AKI (DapG), a monofunctional enzymes found in Bacilli; Region: AAK_AK-DapG-like; cd04246
658172002734	putative catalytic residues [active]
658172002735	putative nucleotide binding site [chemical binding]; other site
658172002736	putative aspartate binding site [chemical binding]; other site
658172002737	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
658172002738	putative allosteric regulatory site; other site
658172002739	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
658172002740	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
658172002741	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
658172002742	S-adenosylmethionine binding site [chemical binding]; other site
658172002743	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
658172002744	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
658172002745	Walker A/P-loop; other site
658172002746	ATP binding site [chemical binding]; other site
658172002747	Q-loop/lid; other site
658172002748	ABC transporter signature motif; other site
658172002749	Walker B; other site
658172002750	D-loop; other site
658172002751	H-loop/switch region; other site
658172002752	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
658172002753	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
658172002754	FtsX-like permease family; Region: FtsX; pfam02687
658172002755	prolyl-tRNA synthetase; Provisional; Region: PRK12325
658172002756	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
658172002757	dimer interface [polypeptide binding]; other site
658172002758	motif 1; other site
658172002759	active site
658172002760	motif 2; other site
658172002761	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
658172002762	active site
658172002763	motif 3; other site
658172002764	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
658172002765	anticodon binding site; other site
658172002766	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
658172002767	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
658172002768	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
658172002769	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
658172002770	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
658172002771	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
658172002772	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
658172002773	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
658172002774	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
658172002775	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
658172002776	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
658172002777	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
658172002778	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
658172002779	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
658172002780	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
658172002781	NADH dehydrogenase subunit 6; Provisional; Region: ND6; MTH00213
658172002782	NADH dehydrogenase subunit 6; Provisional; Region: ND6; MTH00213
658172002783	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
658172002784	4Fe-4S binding domain; Region: Fer4; cl02805
658172002785	4Fe-4S binding domain; Region: Fer4; pfam00037
658172002786	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
658172002787	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
658172002788	NADH dehydrogenase subunit G; Validated; Region: PRK09130
658172002789	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
658172002790	catalytic loop [active]
658172002791	iron binding site [ion binding]; other site
658172002792	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
658172002793	MopB_Res_Cmplx1_Nad11: The second domain of the Nad11/75-kDa subunit of the NADH-quinone oxidoreductase/respiratory complex I/NADH dehydrogenase-1(NDH-1) of eukaryotes and the Nqo3/G subunit of alphaproteobacteria NDH-1. The NADH-quinone oxidoreductase...; Region: MopB_Res-Cmplx1_Nad11; cd02773
658172002794	Domain of unknown function (DUF1982); Region: DUF1982; pfam09326
658172002795	NADH dehydrogenase I subunit F; Provisional; Region: PRK13596
658172002796	SLBB domain; Region: SLBB; pfam10531
658172002797	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
658172002798	NADH dehydrogenase subunit E; Validated; Region: PRK07539
658172002799	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
658172002800	putative dimer interface [polypeptide binding]; other site
658172002801	[2Fe-2S] cluster binding site [ion binding]; other site
658172002802	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
658172002803	NADH dehydrogenase subunit D; Validated; Region: PRK06075
658172002804	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
658172002805	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
658172002806	NADH dehydrogenase subunit B; Validated; Region: PRK06411
658172002807	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
658172002808	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
658172002809	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
658172002810	ring oligomerisation interface [polypeptide binding]; other site
658172002811	ATP/Mg binding site [chemical binding]; other site
658172002812	stacking interactions; other site
658172002813	hinge regions; other site
658172002814	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
658172002815	oligomerisation interface [polypeptide binding]; other site
658172002816	mobile loop; other site
658172002817	roof hairpin; other site
658172002818	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
658172002819	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
658172002820	active site
658172002821	motif I; other site
658172002822	motif II; other site
658172002823	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
658172002824	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
658172002825	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
658172002826	active site
658172002827	Riboflavin kinase; Region: Flavokinase; smart00904
658172002828	glucose/galactose transporter; Region: gluP; TIGR01272
658172002829	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
658172002830	2-octaprenyl-6-methoxyphenyl hydroxylase; Provisional; Region: PRK07494
658172002831	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
658172002832	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
658172002833	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
658172002834	KpsF/GutQ family protein; Region: kpsF; TIGR00393
658172002835	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
658172002836	putative active site [active]
658172002837	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
658172002838	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
658172002839	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
658172002840	active site
658172002841	phosphorylation site [posttranslational modification]
658172002842	intermolecular recognition site; other site
658172002843	dimerization interface [polypeptide binding]; other site
658172002844	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172002845	Walker A motif; other site
658172002846	ATP binding site [chemical binding]; other site
658172002847	Walker B motif; other site
658172002848	arginine finger; other site
658172002849	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
658172002850	DNA-binding interface [nucleotide binding]; DNA binding site
658172002851	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
658172002852	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
658172002853	active site
658172002854	Zn binding site [ion binding]; other site
658172002855	malic enzyme; Reviewed; Region: PRK12862
658172002856	Malic enzyme, N-terminal domain; Region: malic; pfam00390
658172002857	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
658172002858	putative NAD(P) binding site [chemical binding]; other site
658172002859	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
658172002860	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
658172002861	Permease; Region: Permease; pfam02405
658172002862	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
658172002863	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
658172002864	Walker A/P-loop; other site
658172002865	ATP binding site [chemical binding]; other site
658172002866	Q-loop/lid; other site
658172002867	ABC transporter signature motif; other site
658172002868	Walker B; other site
658172002869	D-loop; other site
658172002870	H-loop/switch region; other site
658172002871	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
658172002872	mce related protein; Region: MCE; pfam02470
658172002873	Protein of unknown function (DUF330); Region: DUF330; cl01135
658172002874	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
658172002875	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
658172002876	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
658172002877	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
658172002878	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
658172002879	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
658172002880	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
658172002881	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
658172002882	Rpb1 - Rpb5 interaction site [polypeptide binding]; other site
658172002883	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
658172002884	DNA binding site [nucleotide binding]
658172002885	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
658172002886	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
658172002887	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
658172002888	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
658172002889	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
658172002890	RPB12 interaction site [polypeptide binding]; other site
658172002891	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
658172002892	RPB3 interaction site [polypeptide binding]; other site
658172002893	RPB1 interaction site [polypeptide binding]; other site
658172002894	RPB11 interaction site [polypeptide binding]; other site
658172002895	RPB10 interaction site [polypeptide binding]; other site
658172002896	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
658172002897	peripheral dimer interface [polypeptide binding]; other site
658172002898	core dimer interface [polypeptide binding]; other site
658172002899	L10 interface [polypeptide binding]; other site
658172002900	L11 interface [polypeptide binding]; other site
658172002901	putative EF-Tu interaction site [polypeptide binding]; other site
658172002902	putative EF-G interaction site [polypeptide binding]; other site
658172002903	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
658172002904	23S rRNA interface [nucleotide binding]; other site
658172002905	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
658172002906	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
658172002907	mRNA/rRNA interface [nucleotide binding]; other site
658172002908	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
658172002909	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
658172002910	23S rRNA interface [nucleotide binding]; other site
658172002911	L7/L12 interface [polypeptide binding]; other site
658172002912	putative thiostrepton binding site; other site
658172002913	L25 interface [polypeptide binding]; other site
658172002914	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
658172002915	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
658172002916	putative homodimer interface [polypeptide binding]; other site
658172002917	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
658172002918	heterodimer interface [polypeptide binding]; other site
658172002919	homodimer interface [polypeptide binding]; other site
658172002920	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
658172002921	elongation factor Tu; Reviewed; Region: PRK00049
658172002922	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
658172002923	G1 box; other site
658172002924	GEF interaction site [polypeptide binding]; other site
658172002925	GTP/Mg2+ binding site [chemical binding]; other site
658172002926	Switch I region; other site
658172002927	G2 box; other site
658172002928	G3 box; other site
658172002929	Switch II region; other site
658172002930	G4 box; other site
658172002931	G5 box; other site
658172002932	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
658172002933	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
658172002934	Antibiotic Binding Site [chemical binding]; other site
658172002935	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
658172002936	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
658172002937	Ligand Binding Site [chemical binding]; other site
658172002938	potential frameshift: common BLAST hit: gi|15966483|ref|NP_386836.1| D-3-phosphoglycerate dehydrogenase
658172002939	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cd01494
658172002940	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
658172002941	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
658172002942	catalytic residue [active]
658172002943	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
658172002944	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
658172002945	active site
658172002946	dimerization interface [polypeptide binding]; other site
658172002947	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
658172002948	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
658172002949	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
658172002950	NAD binding site [chemical binding]; other site
658172002951	ATP-grasp domain; Region: ATP-grasp; pfam02222
658172002952	fumarate hydratase; Reviewed; Region: fumC; PRK00485
658172002953	Class II fumarases; Region: Fumarase_classII; cd01362
658172002954	active site
658172002955	tetramer interface [polypeptide binding]; other site
658172002956	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
658172002957	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
658172002958	motif 1; other site
658172002959	active site
658172002960	motif 2; other site
658172002961	motif 3; other site
658172002962	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
658172002963	recombinase A; Provisional; Region: recA; PRK09354
658172002964	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
658172002965	hexamer interface [polypeptide binding]; other site
658172002966	Walker A motif; other site
658172002967	ATP binding site [chemical binding]; other site
658172002968	Walker B motif; other site
658172002969	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
658172002970	ABC transporter; Region: ABC_tran; pfam00005
658172002971	Q-loop/lid; other site
658172002972	ABC transporter signature motif; other site
658172002973	Walker B; other site
658172002974	D-loop; other site
658172002975	H-loop/switch region; other site
658172002976	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
658172002977	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
658172002978	Walker A/P-loop; other site
658172002979	ATP binding site [chemical binding]; other site
658172002980	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00528
658172002981	potential protein location (hypothetical protein CKC_05105 [Candidatus Liberibacter solanacearum CLso-ZC1]) that overlaps RNA (tRNA-E)
658172002982	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
658172002983	structural protein; Region: PHA01972
658172002984	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
658172002985	lipoate-protein ligase B; Provisional; Region: PRK14341
658172002986	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
658172002987	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
658172002988	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
658172002989	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
658172002990	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
658172002991	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
658172002992	active site
658172002993	nucleotide binding site [chemical binding]; other site
658172002994	HIGH motif; other site
658172002995	KMSKS motif; other site
658172002996	DNA gyrase subunit A; Validated; Region: PRK05560
658172002997	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
658172002998	CAP-like domain; other site
658172002999	active site
658172003000	primary dimer interface [polypeptide binding]; other site
658172003001	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
658172003002	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
658172003003	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
658172003004	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
658172003005	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
658172003006	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
658172003007	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
658172003008	dimer interface [polypeptide binding]; other site
658172003009	ssDNA binding site [nucleotide binding]; other site
658172003010	tetramer (dimer of dimers) interface [polypeptide binding]; other site
658172003011	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
658172003012	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
658172003013	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
658172003014	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
658172003015	glutamine synthetase; Provisional; Region: glnA; PRK09469
658172003016	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
658172003017	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
658172003018	DNA primase; Validated; Region: dnaG; PRK05667
658172003019	CHC2 zinc finger; Region: zf-CHC2; cl17510
658172003020	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
658172003021	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
658172003022	active site
658172003023	metal binding site [ion binding]; metal-binding site
658172003024	interdomain interaction site; other site
658172003025	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
658172003026	DNA-directed DNA polymerase III (polc); Region: polc; TIGR00594
658172003027	putative active site [active]
658172003028	putative PHP Thumb interface [polypeptide binding]; other site
658172003029	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
658172003030	generic binding surface I; other site
658172003031	Protein of unknown function (DUF4011); Region: DUF4011; pfam13195
658172003032	AAA domain; Region: AAA_11; pfam13086
658172003033	Part of AAA domain; Region: AAA_19; pfam13245
658172003034	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
658172003035	AAA domain; Region: AAA_30; pfam13604
658172003036	AAA domain; Region: AAA_12; pfam13087
658172003037	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
658172003038	putative active site [active]
658172003039	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
658172003040	dimer interface [polypeptide binding]; other site
658172003041	substrate binding site [chemical binding]; other site
658172003042	metal binding sites [ion binding]; metal-binding site
658172003043	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
658172003044	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
658172003045	G1 box; other site
658172003046	putative GEF interaction site [polypeptide binding]; other site
658172003047	GTP/Mg2+ binding site [chemical binding]; other site
658172003048	Switch I region; other site
658172003049	G2 box; other site
658172003050	G3 box; other site
658172003051	Switch II region; other site
658172003052	G4 box; other site
658172003053	G5 box; other site
658172003054	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
658172003055	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
658172003056	argininosuccinate synthase; Provisional; Region: PRK13820
658172003057	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
658172003058	ANP binding site [chemical binding]; other site
658172003059	Substrate Binding Site II [chemical binding]; other site
658172003060	Substrate Binding Site I [chemical binding]; other site
658172003061	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
658172003062	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
658172003063	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
658172003064	alphaNTD - beta interaction site [polypeptide binding]; other site
658172003065	alphaNTD homodimer interface [polypeptide binding]; other site
658172003066	alphaNTD - beta' interaction site [polypeptide binding]; other site
658172003067	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
658172003068	30S ribosomal protein S11; Validated; Region: PRK05309
658172003069	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
658172003070	30S ribosomal protein S13; Region: bact_S13; TIGR03631
658172003071	adenylate kinase; Reviewed; Region: adk; PRK00279
658172003072	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
658172003073	AMP-binding site [chemical binding]; other site
658172003074	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
658172003075	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
658172003076	SecY translocase; Region: SecY; pfam00344
658172003077	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
658172003078	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
658172003079	23S rRNA binding site [nucleotide binding]; other site
658172003080	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
658172003081	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
658172003082	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
658172003083	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
658172003084	23S rRNA interface [nucleotide binding]; other site
658172003085	L21e interface [polypeptide binding]; other site
658172003086	5S rRNA interface [nucleotide binding]; other site
658172003087	L27 interface [polypeptide binding]; other site
658172003088	L5 interface [polypeptide binding]; other site
658172003089	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
658172003090	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
658172003091	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
658172003092	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
658172003093	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
658172003094	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
658172003095	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
658172003096	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
658172003097	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
658172003098	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
658172003099	RNA binding site [nucleotide binding]; other site
658172003100	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
658172003101	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
658172003102	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
658172003103	23S rRNA interface [nucleotide binding]; other site
658172003104	putative translocon interaction site; other site
658172003105	signal recognition particle (SRP54) interaction site; other site
658172003106	L23 interface [polypeptide binding]; other site
658172003107	trigger factor interaction site; other site
658172003108	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
658172003109	23S rRNA interface [nucleotide binding]; other site
658172003110	5S rRNA interface [nucleotide binding]; other site
658172003111	putative antibiotic binding site [chemical binding]; other site
658172003112	L25 interface [polypeptide binding]; other site
658172003113	L27 interface [polypeptide binding]; other site
658172003114	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
658172003115	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
658172003116	G-X-X-G motif; other site
658172003117	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
658172003118	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
658172003119	putative translocon binding site; other site
658172003120	protein-rRNA interface [nucleotide binding]; other site
658172003121	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
658172003122	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
658172003123	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
658172003124	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
658172003125	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
658172003126	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
658172003127	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
658172003128	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
658172003129	elongation factor Tu; Reviewed; Region: PRK00049
658172003130	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
658172003131	G1 box; other site
658172003132	GEF interaction site [polypeptide binding]; other site
658172003133	GTP/Mg2+ binding site [chemical binding]; other site
658172003134	Switch I region; other site
658172003135	G2 box; other site
658172003136	G3 box; other site
658172003137	Switch II region; other site
658172003138	G4 box; other site
658172003139	G5 box; other site
658172003140	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
658172003141	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
658172003142	Antibiotic Binding Site [chemical binding]; other site
658172003143	elongation factor G; Reviewed; Region: PRK00007
658172003144	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
658172003145	G1 box; other site
658172003146	putative GEF interaction site [polypeptide binding]; other site
658172003147	GTP/Mg2+ binding site [chemical binding]; other site
658172003148	Switch I region; other site
658172003149	G2 box; other site
658172003150	G3 box; other site
658172003151	Switch II region; other site
658172003152	G4 box; other site
658172003153	G5 box; other site
658172003154	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
658172003155	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
658172003156	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
658172003157	Ribosomal protein S7p/S5e; Region: Ribosomal_S7; cl00313
658172003158	Ribosomal protein S7p/S5e; Region: Ribosomal_S7; cl00313
658172003159	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
658172003160	S17 interaction site [polypeptide binding]; other site
658172003161	S8 interaction site; other site
658172003162	16S rRNA interaction site [nucleotide binding]; other site
658172003163	streptomycin interaction site [chemical binding]; other site
658172003164	23S rRNA interaction site [nucleotide binding]; other site
658172003165	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
658172003166	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
658172003167	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
658172003168	carboxyltransferase (CT) interaction site; other site
658172003169	biotinylation site [posttranslational modification]; other site
658172003170	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
658172003171	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
658172003172	ATP-grasp domain; Region: ATP-grasp_4; cl17255
658172003173	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
658172003174	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
658172003175	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
658172003176	Found in ATP-dependent protease La (LON); Region: LON; smart00464
658172003177	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172003178	Walker A motif; other site
658172003179	ATP binding site [chemical binding]; other site
658172003180	Walker B motif; other site
658172003181	arginine finger; other site
658172003182	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
658172003183	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
658172003184	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
658172003185	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
658172003186	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172003187	Walker A motif; other site
658172003188	ATP binding site [chemical binding]; other site
658172003189	Walker B motif; other site
658172003190	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
658172003191	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
658172003192	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
658172003193	oligomer interface [polypeptide binding]; other site
658172003194	active site residues [active]
658172003195	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
658172003196	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
658172003197	Walker A/P-loop; other site
658172003198	ATP binding site [chemical binding]; other site
658172003199	Q-loop/lid; other site
658172003200	ABC transporter signature motif; other site
658172003201	Walker B; other site
658172003202	D-loop; other site
658172003203	H-loop/switch region; other site
658172003204	ABC transporter; Region: ABC_tran_2; pfam12848
658172003205	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
658172003206	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
658172003207	potential protein location (hypothetical protein CKC_05445 [Candidatus Liberibacter solanacearum CLso-ZC1]) that overlaps RNA (tRNA-K)
658172003208	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
658172003209	SmpB-tmRNA interface; other site
658172003210	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
658172003211	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
658172003212	dimer interface [polypeptide binding]; other site
658172003213	active site
658172003214	catalytic residue [active]
658172003215	5'-3' exonuclease, N-terminal resolvase-like domain; Region: 5_3_exonuc_N; pfam02739
658172003216	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
658172003217	active site
658172003218	metal binding site 1 [ion binding]; metal-binding site
658172003219	putative 5' ssDNA interaction site; other site
658172003220	metal binding site 3; metal-binding site
658172003221	metal binding site 2 [ion binding]; metal-binding site
658172003222	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
658172003223	putative DNA binding site [nucleotide binding]; other site
658172003224	putative metal binding site [ion binding]; other site
658172003225	DNA polymerase I - 3'-5' exonuclease and polymerase domains [DNA replication, recombination, and repair]; Region: PolA; COG0749
658172003226	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
658172003227	active site
658172003228	substrate binding site [chemical binding]; other site
658172003229	catalytic site [active]
658172003230	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
658172003231	active site
658172003232	DNA binding site [nucleotide binding]
658172003233	catalytic site [active]
658172003234	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
658172003235	catalytic core [active]
658172003236	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
658172003237	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
658172003238	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
658172003239	glucokinase, proteobacterial type; Region: glk; TIGR00749
658172003240	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
658172003241	nucleotide binding site [chemical binding]; other site
658172003242	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
658172003243	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
658172003244	Cu(I) binding site [ion binding]; other site
658172003245	Transcriptional regulator [Transcription]; Region: LysR; COG0583
658172003246	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
658172003247	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
658172003248	putative effector binding pocket; other site
658172003249	dimerization interface [polypeptide binding]; other site
658172003250	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
658172003251	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
658172003252	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
658172003253	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
658172003254	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
658172003255	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
658172003256	active site
658172003257	HIGH motif; other site
658172003258	KMSK motif region; other site
658172003259	tRNA binding surface [nucleotide binding]; other site
658172003260	DALR anticodon binding domain; Region: DALR_1; smart00836
658172003261	anticodon binding site; other site
658172003262	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
658172003263	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
658172003264	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
658172003265	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
658172003266	putative catalytic site [active]
658172003267	putative phosphate binding site [ion binding]; other site
658172003268	active site
658172003269	metal binding site A [ion binding]; metal-binding site
658172003270	DNA binding site [nucleotide binding]
658172003271	putative AP binding site [nucleotide binding]; other site
658172003272	putative metal binding site B [ion binding]; other site
658172003273	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
658172003274	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
658172003275	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
658172003276	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
658172003277	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
658172003278	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
658172003279	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
658172003280	DNA binding residues [nucleotide binding]
658172003281	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
658172003282	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
658172003283	23S rRNA interface [nucleotide binding]; other site
658172003284	L3 interface [polypeptide binding]; other site
658172003285	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
658172003286	N-acetyl-gamma-glutamyl-phosphate reductase; Provisional; Region: PRK11863
658172003287	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
658172003288	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
658172003289	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
658172003290	dimerization interface 3.5A [polypeptide binding]; other site
658172003291	active site
658172003292	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
658172003293	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
658172003294	putative active site [active]
658172003295	substrate binding site [chemical binding]; other site
658172003296	putative cosubstrate binding site; other site
658172003297	catalytic site [active]
658172003298	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
658172003299	substrate binding site [chemical binding]; other site
658172003300	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
658172003301	active site
658172003302	catalytic residues [active]
658172003303	metal binding site [ion binding]; metal-binding site
658172003304	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
658172003305	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
658172003306	dimerization interface [polypeptide binding]; other site
658172003307	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
658172003308	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
658172003309	dimer interface [polypeptide binding]; other site
658172003310	active site
658172003311	acyl carrier protein; Provisional; Region: acpP; PRK00982
658172003312	3-ketoacyl-(acyl-carrier-protein) reductase NodG; Reviewed; Region: PRK12936
658172003313	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
658172003314	NAD(P) binding site [chemical binding]; other site
658172003315	homotetramer interface [polypeptide binding]; other site
658172003316	homodimer interface [polypeptide binding]; other site
658172003317	active site
658172003318	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
658172003319	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
658172003320	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
658172003321	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
658172003322	intersubunit interface [polypeptide binding]; other site
658172003323	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
658172003324	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
658172003325	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
658172003326	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
658172003327	ABC-ATPase subunit  interface; other site
658172003328	dimer interface [polypeptide binding]; other site
658172003329	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
658172003330	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
658172003331	ABC-ATPase subunit  interface; other site
658172003332	dimer interface [polypeptide binding]; other site
658172003333	putative PBP binding regions; other site
658172003334	Uncharacterized protein conserved in bacteria (DUF2155); Region: DUF2155; cl01970
658172003335	NADH dehydrogenase; Validated; Region: PRK08183
658172003336	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14315
658172003337	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
658172003338	active site
658172003339	substrate binding site [chemical binding]; other site
658172003340	metal binding site [ion binding]; metal-binding site
658172003341	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
658172003342	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172003343	Walker A motif; other site
658172003344	ATP binding site [chemical binding]; other site
658172003345	Walker B motif; other site
658172003346	arginine finger; other site
658172003347	Peptidase family M41; Region: Peptidase_M41; pfam01434
658172003348	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
658172003349	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
658172003350	Ligand Binding Site [chemical binding]; other site
658172003351	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
658172003352	ligand binding site [chemical binding]; other site
658172003353	translocation protein TolB; Provisional; Region: tolB; PRK05137
658172003354	TolB amino-terminal domain; Region: TolB_N; pfam04052
658172003355	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
658172003356	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
658172003357	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
658172003358	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
658172003359	Walker A motif; other site
658172003360	ATP binding site [chemical binding]; other site
658172003361	Walker B motif; other site
658172003362	arginine finger; other site
658172003363	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
658172003364	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
658172003365	RuvA N terminal domain; Region: RuvA_N; pfam01330
658172003366	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
658172003367	active site
658172003368	putative DNA-binding cleft [nucleotide binding]; other site
658172003369	dimer interface [polypeptide binding]; other site
658172003370	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
658172003371	active site
658172003372	DNA binding site [nucleotide binding]
658172003373	structural protein; Region: PHA01972
658172003374	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
658172003375	hypothetical protein; Region: PHA00661
658172003376	hypothetical protein; Region: PHA00662
658172003377	hypothetical protein; Region: PHA00670
658172003378	Bacteriophage head to tail connecting protein; Region: Head-tail_con; pfam12236
658172003379	Terminase-like family; Region: Terminase_6; pfam03237
658172003380	Helix-turn-helix domain; Region: HTH_19; pfam12844
658172003381	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
658172003382	non-specific DNA binding site [nucleotide binding]; other site
658172003383	salt bridge; other site
658172003384	sequence-specific DNA binding site [nucleotide binding]; other site
658172003385	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
658172003386	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
658172003387	non-specific DNA binding site [nucleotide binding]; other site
658172003388	salt bridge; other site
658172003389	sequence-specific DNA binding site [nucleotide binding]; other site
658172003390	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
658172003391	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
658172003392	non-specific DNA binding site [nucleotide binding]; other site
658172003393	salt bridge; other site
658172003394	sequence-specific DNA binding site [nucleotide binding]; other site
658172003395	Prophage antirepressor [Transcription]; Region: COG3617
658172003396	BRO family, N-terminal domain; Region: Bro-N; smart01040
658172003397	Predicted nucleotide-binding protein containing TIR-like domain; Region: TIR-like; cl17861
658172003398	Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cl02488
658172003399	linker region; other site
658172003400	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
658172003401	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
658172003402	Primase C terminal 2 (PriCT-2); Region: PriCT_2; pfam08707
658172003403	D5 N terminal like; Region: D5_N; pfam08706
658172003404	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
658172003405	Protein of unknown function (DUF2800); Region: DUF2800; pfam10926
658172003406	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; cl10713
658172003407	Prophage antirepressor [Transcription]; Region: COG3617
658172003408	BRO family, N-terminal domain; Region: Bro-N; smart01040
658172003409	Protein of unknown function (DUF2815); Region: DUF2815; pfam10991
658172003410	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
658172003411	active site
658172003412	substrate binding site [chemical binding]; other site
658172003413	Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A; cl02626
658172003414	active site
658172003415	DNA binding site [nucleotide binding]
658172003416	catalytic site [active]
658172003417	VRR-NUC domain; Region: VRR_NUC; pfam08774
658172003418	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
658172003419	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
658172003420	ATP binding site [chemical binding]; other site
658172003421	putative Mg++ binding site [ion binding]; other site
658172003422	nucleotide binding region [chemical binding]; other site
658172003423	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
658172003424	ATP-binding site [chemical binding]; other site
658172003425	NAD-dependent DNA ligase LigA; Provisional; Region: ligA; PRK14351
658172003426	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
658172003427	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
658172003428	active site
658172003429	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
658172003430	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
658172003431	active site
658172003432	catalytic residues [active]
658172003433	DNA binding site [nucleotide binding]
658172003434	Int/Topo IB signature motif; other site