-- dump date   	20140619_022256
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_001957188.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_001957196.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_001957204.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_001957205.1	PRINTS: PR00781, Peptidase A8, signal peptidase II; PRODOM: PD004304, Peptidase A8, signal peptidase II
YP_001957216.1	heat shock protein involved in degradation of misfolded proteins
YP_001957218.1	SUPERFAMILY: SSF46689, Homeodomain-like
YP_001957220.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_001957230.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_001957269.1	part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_001957277.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_001957279.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_001957280.1	SUPERFAMILY: SSF48537, Phospholipase C/P1 nuclease, core
YP_001957285.1	involved in the peptidyltransferase reaction during translation
YP_001957292.1	PRINTS: PR00019, Leucine-rich repeat; SMART: SM00368, Leucine-rich repeat, ribonuclease inhibitor subtype
YP_001957300.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_001957301.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_001957302.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_001957303.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_001957313.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_001957314.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_001957315.1	PROFILE: PS50175, Peptidase A2A, retrovirus, catalytic; SUPERFAMILY: SSF50630, Peptidase aspartic, catalytic
YP_001957316.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_001957323.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_001957344.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_001957345.1	PROSITE: PS00539, Pyrokinin, conserved site
YP_001957346.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_001957351.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_001957352.1	late assembly protein
YP_001957354.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_001957356.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_001957357.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_001957359.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_001957363.1	one of the stabilizing components for the large ribosomal subunit
YP_001957364.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_001957368.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_001957369.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_001957370.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_001957371.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_001957379.1	PROSITE: PS00622, Bacterial regulatory protein, LuxR
YP_001957385.1	PROSITE: PS00221, Major intrinsic protein; SUPERFAMILY: SSF49464, Carboxypeptidase-like, regulatory region
YP_001957386.1	SUPERFAMILY: SSF49452, Carbohydrate-binding-like fold
YP_001957395.1	PROSITE: PS00221, Major intrinsic protein; SUPERFAMILY: SSF49464, Carboxypeptidase-like, regulatory region
YP_001957396.1	SUPERFAMILY: SSF49452, Carbohydrate-binding-like fold
YP_001957409.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_001957421.1	functions in MreBCD complex in some organisms
YP_001957428.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_001957429.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_001957433.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_003573007.1	SUPERFAMILY: SSF49464, Carboxypeptidase-like, regulatory region
YP_001957442.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_001957443.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_001957445.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_001957454.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YP_001957456.1	catalyzes the zinc dependent deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis and catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP in fatty acid biosynthesis
YP_001957457.1	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis
YP_001957460.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_001957465.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_001957473.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_001957475.1	catalyzes branch migration in Holliday junction intermediates
YP_003573022.1	SUPERFAMILY: SSF53098, Polynucleotidyl transferase, Ribonuclease H fold
YP_001957514.1	Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001957526.1	SUPERFAMILY: SSF53098, Polynucleotidyl transferase, Ribonuclease H fold
YP_001957534.1	TIGRFAMS: TIGR02453, Conserved hypothetical protein CHP02453
YP_001957536.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_001957545.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_001957546.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_001957558.1	SMART: SM00712, PUR-alpha/beta/gamma, DNA/RNA-binding
YP_001957570.1	SUPERFAMILY: SSF46689, Homeodomain-like
YP_001957578.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin)
YP_001957582.1	PROFILE: PS50297, Ankyrin; SUPERFAMILY: SSF48403, Ankyrin
YP_001957600.1	PROFILE: PS51128, Zinc finger, DksA/TraR C4-type
YP_001957605.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_001957610.1	heat shock protein involved in degradation of misfolded proteins
YP_001957619.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_001957620.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
YP_001957634.1	SUPERFAMILY: SSF46458, Globin-like
YP_001957638.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_001957658.1	SUPERFAMILY: SSF55729, Acyl-CoA N-acyltransferase
YP_001957689.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_001957690.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
YP_001957692.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_001957694.1	SUPERFAMILY: SSF48371, Armadillo-type fold
YP_001957707.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_001957708.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001957722.1	SUPERFAMILY: SSF56719, DNA topoisomerase, type IIA, central
YP_001957724.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_001957726.1	SUPERFAMILY: SSF53098, Polynucleotidyl transferase, Ribonuclease H fold
YP_001957729.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_001957742.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_001957752.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_001957755.1	SUPERFAMILY: SSF53790, Tetrapyrrole methylase
YP_001957756.1	pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient
YP_001957762.1	TIGRFAMS: TIGR02273, 16S rRNA processing protein RimM
YP_001957770.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_001957771.1	TIGRFAMS: TIGR00810, Preprotein translocase SecG subunit
YP_001957773.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_001957778.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_001957810.1	SUPERFAMILY: SSF69189, Penicillin-binding protein-associated
YP_001957818.1	PROFILE: PS50089, Zinc finger, RING-type
YP_001957820.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_001957822.1	TIGRFAMS: TIGR02757, Conserved hypothetical protein CHP02757
YP_001957827.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_001957829.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_001957834.1	SUPERFAMILY: SSF88713, Glycoside hydrolase/deacetylase, beta/alpha-barrel
YP_001957857.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_001957867.1	TIGRFAMS: TIGR00613, Recombination protein O, RecO
YP_001957876.1	This protein performs the mismatch recognition step during the DNA repair process
YP_001957878.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
YP_001957888.1	PROSITE: PS00290, Immunoglobulin/major histocompatibility complex, conserved site; SUPERFAMILY: SSF46689, Homeodomain-like
YP_001957895.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001957901.1	catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine
YP_001957905.1	PRINTS: PR00032, Helix-turn-helix, AraC type; PROFILE: PS01124, Helix-turn-helix, AraC type; SUPERFAMILY: SSF46689, Homeodomain-like
YP_001957911.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins
YP_001957927.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_001957978.1	PROFILE: PS50293, Tetratricopeptide region
YP_001957981.1	PROFILE: PS50111, Chemotaxis methyl-accepting receptor, signalling; SUPERFAMILY: SSF55194, Ribosome recycling factor
YP_001958000.1	SUPERFAMILY: SSF46589, tRNA-binding arm
YP_001958013.1	SUPERFAMILY: SSF53686, Pyridoxal phosphate-dependent enzyme, beta subunit
YP_001958019.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_001958023.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_001958024.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_001958032.1	molecular chaperone
YP_001958033.1	PROFILE: PS50297, Ankyrin; SUPERFAMILY: SSF48403, Ankyrin
YP_001958041.1	PRINTS: PR01590, Helix-turn-helix, Fis-type; SUPERFAMILY: SSF46689, Homeodomain-like
YP_001958070.1	SMART: SM00368, Leucine-rich repeat, ribonuclease inhibitor subtype
YP_001958092.1	responsible for recognizing base lesions in the genome and initiating base excision DNA repair
YP_001958097.1	SUPERFAMILY: SSF53098, Polynucleotidyl transferase, Ribonuclease H fold
YP_001958106.1	PROSITE: PS00018, Calcium-binding EF-hand
YP_001958113.1	catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway
YP_001958126.1	PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP
YP_001958152.1	SUPERFAMILY: SSF55811, NUDIX
YP_001958153.1	PROSITE: PS00120, Lipase, active site
YP_001958175.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_001958176.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_001958196.1	SMART: SM00368, Leucine-rich repeat, ribonuclease inhibitor subtype
YP_001958207.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_001958216.1	PROSITE: PS00687, Aldehyde dehydrogenase, conserved site; TIGRFAMS: TIGR01646, Rhs element Vgr protein
YP_001958221.1	PRINTS: PR01415, Ankyrin; PROFILE: PS50297, Ankyrin; SUPERFAMILY: SSF48403, Ankyrin
YP_001958231.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_001958232.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_001958233.1	with SufCD activates cysteine desulfurase SufS
YP_001958241.1	binds and unfolds substrates as part of the ClpXP protease
YP_001958259.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_001958294.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_001958299.1	PRINTS: PR00830, Peptidase S16, Lon protease;PR01874, DNA repair protein RadA; SMART: SM00382, AAA+ ATPase, core; TIGRFAMS: TIGR00416, DNA repair protein RadA
YP_001958307.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_001958321.1	SUPERFAMILY: SSF48425, SEC7-like
YP_001958326.1	SUPERFAMILY: SSF63562, RNA polymerase Rpb6
YP_001958363.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_001958366.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_001958396.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_001958399.1	SUPERFAMILY: SSF48464, ENTH/VHS
YP_001958408.1	SUPERFAMILY: SSF101447, Actin-binding FH2
YP_001958420.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_001958421.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_001958422.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_001958423.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_001958424.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_001958425.1	SUPERFAMILY: SSF46689, Homeodomain-like
YP_001958428.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_001958439.1	SUPERFAMILY: SSF46689, Homeodomain-like
YP_001958450.1	catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate
YP_001958453.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_001958456.1	SUPERFAMILY: SSF51045, WW/Rsp5/WWP
YP_001958460.1	PROSITE: PS00639, Peptidase, cysteine peptidase active site