-- dump date 20140619_013044 -- class Genbank::misc_feature -- table misc_feature_note -- id note 216591000001 Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999 216591000002 10 probable transmembrane helices predicted for BCAL0001 by TMHMM2.0 at aa 15-37, 44-66, 114-136, 157-176, 191-213, 233-264, 279-301, 306-328, 338-357 and 369-391 216591000003 HMMPfam hit to PF00999, Sodium/hydrogen exchanger family, score 8.4e-11 216591000004 gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516 216591000005 carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050 216591000006 HMMPfam hit to PF04107, Glutamate-cysteine ligase family 2(GCS2), score 1.3e-60 216591000007 Transcriptional regulators [Transcription]; Region: MarR; COG1846 216591000008 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591000009 putative DNA binding site [nucleotide binding]; other site 216591000010 putative Zn2+ binding site [ion binding]; other site 216591000011 HMMPfam hit to PF01047, MarR family, score 1.1e-12 216591000012 HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family, score 1.4e-05 216591000013 GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518 216591000014 Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741 216591000015 catalytic triad [active] 216591000016 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 4.3e-13 216591000017 PS00442 Glutamine amidotransferases class-I active site. 216591000018 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 216591000019 Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis. Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932 216591000020 active site 216591000021 FMN binding site [chemical binding]; other site 216591000022 substrate binding site [chemical binding]; other site 216591000023 homotetramer interface [polypeptide binding]; other site 216591000024 catalytic residue [active] 216591000025 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 4.2e-68 216591000026 Proteins containing SET domain [General function prediction only]; Region: COG2940 216591000027 SET domain; Region: SET; pfam00856 216591000028 HMMPfam hit to PF00856, SET domain, score 1.3e-24 216591000029 Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521 216591000030 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591000031 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591000032 dimer interface [polypeptide binding]; other site 216591000033 phosphorylation site [posttranslational modification] 216591000034 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591000035 ATP binding site [chemical binding]; other site 216591000036 Mg2+ binding site [ion binding]; other site 216591000037 G-X-G motif; other site 216591000038 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2.6e-36 216591000039 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.6e-14 216591000040 HMMPfam hit to PF00672, HAMP domain, score 2.7e-06 216591000041 2 probable transmembrane helices predicted for BCAL0007 by TMHMM2.0 at aa 20-39 and 161-183 216591000042 HMMPfam hit to PF08521, Two-component sensor kinase N-terminal, score 3.8e-48 216591000043 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591000044 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591000045 active site 216591000046 phosphorylation site [posttranslational modification] 216591000047 intermolecular recognition site; other site 216591000048 dimerization interface [polypeptide binding]; other site 216591000049 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591000050 DNA binding site [nucleotide binding] 216591000051 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.5e-22 216591000052 HMMPfam hit to PF00072, Response regulator receiver domain, score 6.5e-36 216591000053 Protein of unknown function (DUF3717); Region: DUF3717; pfam12512 216591000054 PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme. DCoH stimulates gene expression by...; Region: PCD_DCoH_subfamily_b; cd00914 216591000055 aromatic arch; other site 216591000056 DCoH dimer interaction site [polypeptide binding]; other site 216591000057 DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site 216591000058 DCoH tetramer interaction site [polypeptide binding]; other site 216591000059 substrate binding site [chemical binding]; other site 216591000060 HMMPfam hit to PF01329, Pterin 4 alpha carbinolamine dehydratase, score 2.4e-36 216591000061 Prokaryotic phenylalanine-4-hydroxylase (pro_PheOH); a member of the biopterin-dependent aromatic amino acid hydroxylase family of non-heme, iron(II)-dependent enzymes that also includes the eukaryotic proteins, phenylalanine-4-hydroxylase (eu_PheOH); Region: pro_PheOH; cd03348 216591000062 cofactor binding site; other site 216591000063 metal binding site [ion binding]; metal-binding site 216591000064 HMMPfam hit to PF00351, Biopterin-dependent aromatic amino acid h, score 2e-11 216591000065 PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. 216591000066 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591000067 Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412 216591000068 putative DNA binding site [nucleotide binding]; other site 216591000069 putative Zn2+ binding site [ion binding]; other site 216591000070 AsnC family; Region: AsnC_trans_reg; pfam01037 216591000071 Predicted helix-turn-helix motif with score 1383.000, SD 3.90 at aa 26-47, sequence ATHQQLGEEVPLSPSQIGRRLQ 216591000072 HMMPfam hit to PF01037, AsnC family, score 3e-28 216591000073 Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily; Region: CYTH-like_AC_IV-like; cd07890 216591000074 putative active site [active] 216591000075 putative metal binding residues [ion binding]; other site 216591000076 signature motif; other site 216591000077 putative triphosphate binding site [ion binding]; other site 216591000078 dimer interface [polypeptide binding]; other site 216591000079 HMMPfam hit to PF01928, CYTH domain, score 2.4e-19 216591000080 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591000081 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591000082 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591000083 dimerization interface [polypeptide binding]; other site 216591000084 HMMPfam hit to PF03466, LysR substrate binding domain, score 2e-27 216591000085 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 9.4e-20 216591000086 Predicted helix-turn-helix motif with score 1604.000, SD 4.65 at aa 16-37, sequence GNLTRAAAQLHLTQPAVSLQIK 216591000087 choline dehydrogenase; Validated; Region: PRK02106 216591000088 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 216591000089 HMMPfam hit to PF00732, GMC oxidoreductase, score 1.8e-105 216591000090 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000091 PS00624 GMC oxidoreductases signature 2. 216591000092 HMMPfam hit to PF05199, GMC oxidoreductase, score 2.5e-53 216591000093 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 216591000094 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 216591000095 Walker A/P-loop; other site 216591000096 ATP binding site [chemical binding]; other site 216591000097 Q-loop/lid; other site 216591000098 ABC transporter signature motif; other site 216591000099 Walker B; other site 216591000100 D-loop; other site 216591000101 H-loop/switch region; other site 216591000102 HMMPfam hit to PF00005, ABC transporter, score 5.9e-45 216591000103 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000104 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 216591000105 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 216591000106 Walker A/P-loop; other site 216591000107 ATP binding site [chemical binding]; other site 216591000108 Q-loop/lid; other site 216591000109 ABC transporter signature motif; other site 216591000110 Walker B; other site 216591000111 D-loop; other site 216591000112 H-loop/switch region; other site 216591000113 HMMPfam hit to PF00005, ABC transporter, score 1.1e-34 216591000114 PS00211 ABC transporters family signature. 216591000115 Periplasmic binding protein; Region: Peripla_BP_6; pfam13458 216591000116 Periplasmic solute-binding domain of active transport proteins that belong to the type I periplasmic binding fold protein family; Region: PBP1_SBP_like_1; cd06327 216591000117 putative ligand binding site [chemical binding]; other site 216591000118 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591000119 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 216591000120 TM-ABC transporter signature motif; other site 216591000121 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 2.1e-35 216591000122 8 probable transmembrane helices predicted for BCAL0018 by TMHMM2.0 at aa 15-37, 39-61, 65-87, 100-122, 148-167, 199-221, 236-258 and 265-287 216591000123 ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177 216591000124 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 216591000125 TM-ABC transporter signature motif; other site 216591000126 8 probable transmembrane helices predicted for BCAL0019 by TMHMM2.0 at aa 5-27, 42-64, 77-99, 103-122, 151-173, 203-225, 238-260 and 284-306 216591000127 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 6.5e-20 216591000128 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591000129 Type I periplasmic binding component of ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in uptake of amino acids; Region: PBP1_ABC-type_HAAT_like; cd06333 216591000130 putative ligand binding site [chemical binding]; other site 216591000131 HMMPfam hit to PF01094, Receptor family ligand binding region, score 2e-06 216591000132 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 216591000133 TM-ABC transporter signature motif; other site 216591000134 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 5e-05 216591000135 9 probable transmembrane helices predicted for BCAL0021 by TMHMM2.0 at aa 17-39, 61-83, 96-118, 123-145, 157-179, 199-221, 253-275, 290-312 and 325-342 216591000136 ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177 216591000137 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 216591000138 TM-ABC transporter signature motif; other site 216591000139 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 216591000140 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 216591000141 Walker A/P-loop; other site 216591000142 ATP binding site [chemical binding]; other site 216591000143 Q-loop/lid; other site 216591000144 ABC transporter signature motif; other site 216591000145 Walker B; other site 216591000146 D-loop; other site 216591000147 H-loop/switch region; other site 216591000148 9 probable transmembrane helices predicted for BCAL0022 by TMHMM2.0 at aa 9-28, 32-54, 61-80, 84-106, 113-132, 161-183, 207-229, 249-271 and 284-306 216591000149 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 2.5e-28 216591000150 HMMPfam hit to PF00005, ABC transporter, score 7.5e-56 216591000151 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000152 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 216591000153 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 216591000154 Walker A/P-loop; other site 216591000155 ATP binding site [chemical binding]; other site 216591000156 Q-loop/lid; other site 216591000157 ABC transporter signature motif; other site 216591000158 Walker B; other site 216591000159 D-loop; other site 216591000160 H-loop/switch region; other site 216591000161 HMMPfam hit to PF00005, ABC transporter, score 7.2e-46 216591000162 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000163 PS00211 ABC transporters family signature. 216591000164 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192 216591000165 tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137 216591000166 NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206 216591000167 GidA associated domain 3; Region: GIDA_assoc_3; pfam13932 216591000168 HMMPfam hit to PF01134, Glucose inhibited division protein A, score 1.4e-274 216591000169 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.0016 216591000170 PS01280 Glucose inhibited division protein A family signature 1. 216591000171 PS01281 Glucose inhibited division protein A family signature 2. 216591000172 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357 216591000173 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591000174 S-adenosylmethionine binding site [chemical binding]; other site 216591000175 HMMPfam hit to PF02527, Glucose inhibited division protein, score 5.5e-58 216591000176 HMMPfam hit to PF08241, Methyltransferase domain, score 0.0011 216591000177 ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192 216591000178 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 216591000179 P-loop; other site 216591000180 Magnesium ion binding site [ion binding]; other site 216591000181 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 216591000182 Magnesium ion binding site [ion binding]; other site 216591000183 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 1.4e-58 216591000184 Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475 216591000185 ParB-like nuclease domain; Region: ParBc; pfam02195 216591000186 HMMPfam hit to PF02195, ParB-like nuclease domain, score 2e-35 216591000187 Predicted helix-turn-helix motif with score 1768.000, SD 5.21 at aa 148-169, sequence FTHEQAAESVGRSRSAVSNLLR 216591000188 Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221 216591000189 transmembrane helices; other site 216591000190 Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055 216591000191 Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221 216591000192 9 probable transmembrane helices predicted for BCAL0028 by TMHMM2.0 at aa 13-35, 91-113, 125-147, 167-189, 210-243, 253-275, 288-310, 320-342 and 351-373 216591000193 HMMPfam hit to PF03600, Citrate transporter, score 5.2e-05 216591000194 ATP synthase I chain; Region: ATP_synt_I; cl09170 216591000195 4 probable transmembrane helices predicted for BCAL0029 by TMHMM2.0 at aa 68-87, 91-113, 126-148 and 153-172 216591000196 F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356 216591000197 F0F1 ATP synthase subunit A; Validated; Region: PRK05815 216591000198 HMMPfam hit to PF00119, ATP synthase A chain, score 2.9e-55 216591000199 5 probable transmembrane helices predicted for BCAL0030 by TMHMM2.0 at aa 47-66, 95-117, 152-171, 218-240 and 260-282 216591000200 PS00449 ATP synthase a subunit signature. 216591000201 F0F1 ATP synthase subunit C; Validated; Region: PRK06876 216591000202 HMMPfam hit to PF00137, ATP synthase subunit C, score 5e-18 216591000203 2 probable transmembrane helices predicted for BCAL0031 by TMHMM2.0 at aa 15-37 and 58-80 216591000204 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000205 PS00605 ATP synthase c subunit signature. 216591000206 F0F1 ATP synthase subunit B; Validated; Region: PRK05759 216591000207 F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711 216591000208 HMMPfam hit to PF00430, ATP synthase B/B' CF(0), score 3e-25 216591000209 F0F1 ATP synthase subunit delta; Validated; Region: PRK05758 216591000210 ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213 216591000211 HMMPfam hit to PF00213, ATP synthase delta (OSCP) subunit, score 9.6e-32 216591000212 F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281 216591000213 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 216591000214 F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132 216591000215 beta subunit interaction interface [polypeptide binding]; other site 216591000216 Walker A motif; other site 216591000217 ATP binding site [chemical binding]; other site 216591000218 Walker B motif; other site 216591000219 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 216591000220 HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 2.2e-19 216591000221 HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 5.7e-122 216591000222 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000223 PS00152 ATP synthase alpha and beta subunits signature. 216591000224 HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C termin, score 1.6e-33 216591000225 mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151 216591000226 core domain interface [polypeptide binding]; other site 216591000227 delta subunit interface [polypeptide binding]; other site 216591000228 epsilon subunit interface [polypeptide binding]; other site 216591000229 HMMPfam hit to PF00231, ATP synthase, score 7.8e-134 216591000230 PS00153 ATP synthase gamma subunit signature. 216591000231 F0F1 ATP synthase subunit beta; Validated; Region: PRK09280 216591000232 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 216591000233 F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133 216591000234 alpha subunit interaction interface [polypeptide binding]; other site 216591000235 Walker A motif; other site 216591000236 ATP binding site [chemical binding]; other site 216591000237 Walker B motif; other site 216591000238 inhibitor binding site; inhibition site 216591000239 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 216591000240 HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 3.2e-23 216591000241 HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 1.9e-96 216591000242 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000243 PS00152 ATP synthase alpha and beta subunits signature. 216591000244 HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C termin, score 4.6e-48 216591000245 F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571 216591000246 mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152 216591000247 gamma subunit interface [polypeptide binding]; other site 216591000248 epsilon subunit interface [polypeptide binding]; other site 216591000249 LBP interface [polypeptide binding]; other site 216591000250 HMMPfam hit to PF02823, ATP synthase, Delta/Epsilon chain, beta, score 2.5e-31 216591000251 HMMPfam hit to PF00401, ATP synthase, Delta/Epsilon chain, long, score 0.0026 216591000252 AMP-binding domain protein; Validated; Region: PRK08315 216591000253 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591000254 Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917 216591000255 acyl-activating enzyme (AAE) consensus motif; other site 216591000256 putative AMP binding site [chemical binding]; other site 216591000257 putative active site [active] 216591000258 putative CoA binding site [chemical binding]; other site 216591000259 HMMPfam hit to PF00501, AMP-binding enzyme, score 8e-129 216591000260 PS00455 Putative AMP-binding domain signature. 216591000261 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000262 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591000263 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591000264 substrate binding pocket [chemical binding]; other site 216591000265 membrane-bound complex binding site; other site 216591000266 hinge residues; other site 216591000267 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 5.9e-22 216591000268 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591000269 Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717 216591000270 substrate binding site [chemical binding]; other site 216591000271 active site 216591000272 HMMPfam hit to PF01208, Uroporphyrinogen decarboxylase (URO-D), score 2.6e-165 216591000273 PS00906 Uroporphyrinogen decarboxylase signature 1. 216591000274 PS00907 Uroporphyrinogen decarboxylase signature 2. 216591000275 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000276 Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198 216591000277 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 216591000278 ATP binding site [chemical binding]; other site 216591000279 putative Mg++ binding site [ion binding]; other site 216591000280 helicase superfamily c-terminal domain; Region: HELICc; smart00490 216591000281 nucleotide binding region [chemical binding]; other site 216591000282 ATP-binding site [chemical binding]; other site 216591000283 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 1.5e-09 216591000284 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 3.9e-18 216591000285 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000286 PS00036 bZIP transcription factors basic domain signature. 216591000287 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 2.4e-06 216591000288 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809 216591000289 Predicted transcriptional regulator [Transcription]; Region: COG3905 216591000290 Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506 216591000291 Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125 216591000292 Glutamate binding site [chemical binding]; other site 216591000293 NAD binding site [chemical binding]; other site 216591000294 catalytic residues [active] 216591000295 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 216591000296 HMMPfam hit to PF01619, Proline dehydrogenase, score 6.9e-174 216591000297 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.7e-109 216591000298 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591000299 PS00070 Aldehyde dehydrogenases cysteine active site. 216591000300 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591000301 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 216591000302 dimerization interface [polypeptide binding]; other site 216591000303 ligand binding site [chemical binding]; other site 216591000304 HMMPfam hit to PF01094, Receptor family ligand binding region, score 2.9e-48 216591000305 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591000306 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591000307 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591000308 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591000309 Predicted helix-turn-helix motif with score 1703.000, SD 4.99 at aa 20-41, sequence EAIRAVARTHGLSHSTVSQWYA 216591000310 putative transposase OrfB; Reviewed; Region: PHA02517 216591000311 HTH-like domain; Region: HTH_21; pfam13276 216591000312 Integrase core domain; Region: rve; pfam00665 216591000313 Integrase core domain; Region: rve_2; pfam13333 216591000314 HMMPfam hit to PF00665, Integrase core domain, score 5.1e-42 216591000315 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06187 216591000316 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591000317 Bacterial Bile acid CoA ligases and similar proteins; Region: BACL_like; cd05929 216591000318 acyl-activating enzyme (AAE) consensus motif; other site 216591000319 acyl-activating enzyme (AAE) consensus motif; other site 216591000320 putative AMP binding site [chemical binding]; other site 216591000321 putative active site [active] 216591000322 putative CoA binding site [chemical binding]; other site 216591000323 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.9e-114 216591000324 PS00455 Putative AMP-binding domain signature. 216591000325 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591000326 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591000327 active site 216591000328 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 1.5e-44 216591000329 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 8.6e-06 216591000330 PS00073 Acyl-CoA dehydrogenases signature 2. 216591000331 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 1.6e-16 216591000332 PS00072 Acyl-CoA dehydrogenases signature 1. 216591000333 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591000334 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591000335 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.6e-12 216591000336 PS01081 Bacterial regulatory proteins, tetR family signature. 216591000337 Predicted helix-turn-helix motif with score 1231.000, SD 3.38 at aa 55-76, sequence ATIREIAAVAGVSIGTFYEYFG 216591000338 putative aminotransferase; Provisional; Region: PRK12414 216591000339 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591000340 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591000341 homodimer interface [polypeptide binding]; other site 216591000342 catalytic residue [active] 216591000343 HMMPfam hit to PF00155, Aminotransferase class I and II, score 2.3e-59 216591000344 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591000345 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591000346 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591000347 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-31 216591000348 lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096 216591000349 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591000350 substrate binding pocket [chemical binding]; other site 216591000351 membrane-bound complex binding site; other site 216591000352 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 6.3e-75 216591000353 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591000354 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 216591000355 FAD binding domain; Region: FAD_binding_4; pfam01565 216591000356 HMMPfam hit to PF01565, FAD binding domain, score 3.6e-47 216591000357 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591000358 HMMPfam hit to PF02913, FAD linked oxidases, C-terminal domain, score 2e-48 216591000359 Predicted transcriptional regulators [Transcription]; Region: COG1695 216591000360 Transcriptional regulator PadR-like family; Region: PadR; cl17335 216591000361 HMMPfam hit to PF03551, Transcriptional regulator PadR-like family, score 6.4e-09 216591000362 Cd(II)/Pb(II)-responsive transcriptional regulator; Region: CadR-PbrR; TIGR02047 216591000363 Helix-Turn-Helix DNA binding domain of the CadR and PbrR transcription regulators; Region: HTH_CadR-PbrR; cd04784 216591000364 DNA binding residues [nucleotide binding] 216591000365 dimer interface [polypeptide binding]; other site 216591000366 putative metal binding site [ion binding]; other site 216591000367 HMMPfam hit to PF00376, MerR family regulatory protein, score 4.3e-12 216591000368 PS00552 Bacterial regulatory proteins, merR family signature. 216591000369 Predicted helix-turn-helix motif with score 1631.000, SD 4.74 at aa 1-22, sequence MKIGELAKAARCTPETIRFYEK 216591000370 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 216591000371 Heavy-metal-associated domain; Region: HMA; pfam00403 216591000372 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 216591000373 6 probable transmembrane helices predicted for BCAL0055 by TMHMM2.0 at aa 104-126, 146-168, 308-330, 345-367, 650-672 and 677-699 216591000374 HMMPfam hit to PF00122, E1-E2 ATPase, score 6.2e-91 216591000375 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.1e-33 216591000376 PS00154 E1-E2 ATPases phosphorylation site. 216591000377 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000378 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591000379 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591000380 GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445 216591000381 HMMPfam hit to PF06445, Bacterial transcription activator, effect, score 6.3e-41 216591000382 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pro, score 6.4e-05 216591000383 PS00041 Bacterial regulatory proteins, araC family signature. 216591000384 Conserved TM helix; Region: TM_helix; pfam05552 216591000385 HMMPfam hit to PF05552, Conserved TM helix, score 5.2e-13 216591000386 11 probable transmembrane helices predicted for BCAL0057 by TMHMM2.0 at aa 34-56, 77-99, 119-141, 175-197, 207-229, 262-284, 299-321, 358-377, 397-416, 429-448 and 458-480 216591000387 HMMPfam hit to PF05552, Conserved TM helix, score 1.3e-11 216591000388 HMMPfam hit to PF05552, Conserved TM helix, score 2.7e-16 216591000389 HMMPfam hit to PF05552, Conserved TM helix, score 1.2e-11 216591000390 ethanolamine permease; Region: 2A0305; TIGR00908 216591000391 hypothetical protein; Provisional; Region: PHA02764 216591000392 12 probable transmembrane helices predicted for BCAL0058 by TMHMM2.0 at aa 28-50, 54-76, 102-124, 139-161, 168-190, 205-227, 240-262, 292-314, 342-359, 374-396, 409-431 and 436-453 216591000393 HMMPfam hit to PF00324, Amino acid permease, score 1.1e-07 216591000394 ethanolamine ammonia lyase large subunit; Provisional; Region: PRK15067 216591000395 Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751 216591000396 HMMPfam hit to PF06751, Ethanolamine ammonia lyase large subunit (Eu, score 0 216591000397 ethanolamine ammonia-lyase small subunit; Provisional; Region: PRK05465 216591000398 HMMPfam hit to PF05985, Ethanolamine ammonia-lyase light chain (EutC, score 7.7e-112 216591000399 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591000400 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591000401 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_7; cd08476 216591000402 putative effector binding pocket; other site 216591000403 putative dimerization interface [polypeptide binding]; other site 216591000404 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.2e-58 216591000405 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 9.8e-16 216591000406 PS00044 Bacterial regulatory proteins, lysR family signature. 216591000407 Predicted helix-turn-helix motif with score 1053.000, SD 2.77 at aa 17-38, sequence LSFVAAGRALGISASAVGKTIA 216591000408 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591000409 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591000410 14 probable transmembrane helices predicted for BCAL0062 by TMHMM2.0 at aa 19-41, 56-78, 87-109, 113-132, 145-167, 172-191, 203-225, 235-254, 274-296, 311-328, 333-355, 370-392, 413-435 and 485-504 216591000411 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.9e-48 216591000412 PS00216 Sugar transport proteins signature 1. 216591000413 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000414 Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381 216591000415 HMMPfam hit to PF01243, Pyridoxamine 5'-phosphate oxidase, score 1.2e-10 216591000416 Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116 216591000417 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591000418 NAD(P) binding site [chemical binding]; other site 216591000419 catalytic residues [active] 216591000420 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.7e-224 216591000421 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000422 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591000423 PS00070 Aldehyde dehydrogenases cysteine active site. 216591000424 Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381 216591000425 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591000426 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591000427 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00013 216591000428 Predicted helix-turn-helix motif with score 1472.000, SD 4.20 at aa 256-277, sequence VGVPELCEQLHVSRRTLQYCFQ 216591000429 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00029 216591000430 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 216591000431 thiamine pyrophosphate protein; Validated; Region: PRK08199 216591000432 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 216591000433 PYR/PP interface [polypeptide binding]; other site 216591000434 dimer interface [polypeptide binding]; other site 216591000435 TPP binding site [chemical binding]; other site 216591000436 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591000437 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568 216591000438 TPP-binding site [chemical binding]; other site 216591000439 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 7.2e-55 216591000440 PS00187 Thiamine pyrophosphate enzymes signature. 216591000441 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 4.3e-07 216591000442 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 3.3e-49 216591000443 Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016 216591000444 HMMPfam hit to PF05016, Plasmid stabilisation system protein, score 1.3e-21 216591000445 L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720 216591000446 Serine dehydratase beta chain; Region: SDH_beta; pfam03315 216591000447 Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313 216591000448 HMMPfam hit to PF03313, Serine dehydratase alpha chain, score 5.4e-170 216591000449 HMMPfam hit to PF03315, Serine dehydratase beta chain, score 4.9e-71 216591000450 Alginate lyase; Region: Alginate_lyase; pfam05426 216591000451 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000452 1 probable transmembrane helix predicted for BCAL0072 by TMHMM2.0 at aa 20-42 216591000453 glycine dehydrogenase; Provisional; Region: PRK05367 216591000454 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 216591000455 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591000456 catalytic residue [active] 216591000457 Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613 216591000458 tetramer interface [polypeptide binding]; other site 216591000459 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591000460 catalytic residue [active] 216591000461 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0039 216591000462 HMMPfam hit to PF02347, Glycine cleavage system P-protein, score 1.9e-247 216591000463 Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848 216591000464 lipoyl attachment site [posttranslational modification]; other site 216591000465 HMMPfam hit to PF01597, Glycine cleavage H-protein, score 8.5e-54 216591000466 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 216591000467 glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389 216591000468 Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669 216591000469 HMMPfam hit to PF01571, Glycine cleavage T-protein (aminomethyl tran, score 3.3e-109 216591000470 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000471 putative oxidoreductase; Provisional; Region: PRK11579 216591000472 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 216591000473 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 6.2e-17 216591000474 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 1.9e-30 216591000475 SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases. FeeA and FeeB are part of a biosynthetic gene cluster and may participate in the biosynthesis of long-chain N-acyltyrosines by providing saturated and unsaturated fatty acids, which it...; Region: FeeA_FeeB_like; cd01836 216591000476 active site 216591000477 catalytic triad [active] 216591000478 oxyanion hole [active] 216591000479 ATP-dependent DNA helicase Rep; Region: rep; TIGR01074 216591000480 Part of AAA domain; Region: AAA_19; pfam13245 216591000481 Family description; Region: UvrD_C_2; pfam13538 216591000482 HMMPfam hit to PF00580, UvrD/REP helicase, score 2.2e-185 216591000483 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000484 Cytochrome c5 [Energy production and conversion]; Region: CycB; COG3245 216591000485 Cytochrome c5 [Energy production and conversion]; Region: CycB; COG3245 216591000486 HMMPfam hit to PF00034, Cytochrome c, score 0.0011 216591000487 PS00190 Cytochrome c family heme-binding site signature. 216591000488 HMMPfam hit to PF00034, Cytochrome c, score 0.00049 216591000489 PS00190 Cytochrome c family heme-binding site signature. 216591000490 1 probable transmembrane helix predicted for BCAL0080 by TMHMM2.0 at aa 15-37 216591000491 BcenGI1 216591000492 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 216591000493 active site 216591000494 DNA binding site [nucleotide binding] 216591000495 Int/Topo IB signature motif; other site 216591000496 HMMPfam hit to PF00589, Phage integrase family, score 1.5e-34 216591000497 Helix-turn-helix domain; Region: HTH_17; pfam12728 216591000498 DNA primase domain-containing protein; Region: PHA02415 216591000499 TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029 216591000500 active site 216591000501 metal binding site [ion binding]; metal-binding site 216591000502 interdomain interaction site; other site 216591000503 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000504 Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606 216591000505 HMMPfam hit to PF04606, Ogr/Delta-like zinc finger, score 6.2e-22 216591000506 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591000507 non-specific DNA binding site [nucleotide binding]; other site 216591000508 salt bridge; other site 216591000509 sequence-specific DNA binding site [nucleotide binding]; other site 216591000510 IBS2? 216591000511 IBS1? 216591000512 Group II intron - EBS2 216591000513 Group II intron - EBS1? 216591000514 RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651 216591000515 Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078 216591000516 putative active site [active] 216591000517 putative NTP binding site [chemical binding]; other site 216591000518 putative nucleic acid binding site [nucleotide binding]; other site 216591000519 HMMPfam hit to PF00078, Reverse transcriptase (RNA-dependent DNA pol, score 1.5e-62 216591000520 tail protein; Provisional; Region: D; PHA02561 216591000521 HMMPfam hit to PF05954, Phage late control gene D protein (GPD), score 1.2e-151 216591000522 Phage P2 GpU; Region: Phage_P2_GpU; pfam06995 216591000523 HMMPfam hit to PF06995, Phage P2 GpU, score 1e-51 216591000524 2 probable transmembrane helices predicted for BCAL0091 by TMHMM2.0 at aa 571-593 and 614-636 216591000525 Phage P2 GpE; Region: Phage_P2_GpE; pfam06528 216591000526 HMMPfam hit to PF06528, Phage P2 GpE, score 4.5e-15 216591000527 Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109 216591000528 HMMPfam hit to PF06158, Phage tail protein E, score 7.1e-40 216591000529 major tail tube protein; Provisional; Region: FII; PHA02600 216591000530 HMMPfam hit to PF04985, Phage tail tube protein FII, score 4.1e-82 216591000531 major tail sheath protein; Provisional; Region: FI; PHA02560 216591000532 HMMPfam hit to PF04984, Phage tail sheath protein, score 4.9e-164 216591000533 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 216591000534 long tail fiber, proximal subunit; Provisional; Region: 34; PHA02584 216591000535 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 5.3e-07 216591000536 Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684 216591000537 Baseplate J-like protein; Region: Baseplate_J; cl01294 216591000538 HMMPfam hit to PF04865, Baseplate J-like protein, score 3.9e-81 216591000539 Gene 25-like lysozyme; Region: GPW_gp25; cl01403 216591000540 HMMPfam hit to PF04965, GPW / gp25 family, score 1.1e-26 216591000541 phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644 216591000542 Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540 216591000543 HMMPfam hit to PF04717, Phage-related baseplate assembly protein, score 2.5e-39 216591000544 P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891 216591000545 HMMPfam hit to PF06891, P2 phage tail completion protein R (GpR), score 5.9e-39 216591000546 phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495 216591000547 1 probable transmembrane helix predicted for BCAL0103 by TMHMM2.0 at aa 5-27 216591000548 Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409 216591000549 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 216591000550 Protein of unknown function (DUF3380); Region: DUF3380; pfam11860 216591000551 HMMPfam hit to PF01471, Putative peptidoglycan binding domain, score 1.7e-17 216591000552 Protein of unknown function (DUF754); Region: DUF754; pfam05449 216591000553 HMMPfam hit to PF05449, Protein of unknown function (DUF754), score 1.4e-17 216591000554 3 probable transmembrane helices predicted for BCAL0105 by TMHMM2.0 at aa 4-23, 35-54 and 59-81 216591000555 3 probable transmembrane helices predicted for BCAL0106 by TMHMM2.0 at aa 20-42, 54-76 and 81-98 216591000556 Phage Tail Protein X; Region: Phage_tail_X; pfam05489 216591000557 HMMPfam hit to PF05489, Phage Tail Protein X, score 1.2e-25 216591000558 Uncharacterized conserved protein [Function unknown]; Region: COG4278 216591000559 TIGR04222 domain; Region: near_uncomplex 216591000560 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000561 4 probable transmembrane helices predicted for BCAL0108 by TMHMM2.0 at aa 217-239, 363-380, 385-404 and 460-482 216591000562 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000563 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591000564 TPR motif; other site 216591000565 binding surface 216591000566 TPR repeat; Region: TPR_11; pfam13414 216591000567 TPR repeat; Region: TPR_11; pfam13414 216591000568 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591000569 binding surface 216591000570 TPR motif; other site 216591000571 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 216591000572 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 9.2e-06 216591000573 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 0.019 216591000574 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.4 216591000575 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.0085 216591000576 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.5e-06 216591000577 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 0.023 216591000578 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.7e-07 216591000579 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 5.9e-09 216591000580 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 9.6e-05 216591000581 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000582 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 216591000583 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399 216591000584 inhibitor-cofactor binding pocket; inhibition site 216591000585 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591000586 catalytic residue [active] 216591000587 HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 1.3e-100 216591000588 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.00017 216591000589 Tetratricopeptide repeat; Region: TPR_16; pfam13432 216591000590 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591000591 TPR motif; other site 216591000592 binding surface 216591000593 Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914 216591000594 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591000595 TPR motif; other site 216591000596 binding surface 216591000597 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 216591000598 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.028 216591000599 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 3e-06 216591000600 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.33 216591000601 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0049 216591000602 flagellar capping protein; Reviewed; Region: fliD; PRK08032 216591000603 Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195 216591000604 HMMPfam hit to PF07195, Flagellar hook-associated protein, score 1.6e-59 216591000605 HMMPfam hit to PF07196, Flagellin hook IN motif, score 2.7e-07 216591000606 HMMPfam hit to PF02465, Flagellar hook-associated protein, score 4.1e-18 216591000607 flagellin; Reviewed; Region: PRK08869 216591000608 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 216591000609 Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700 216591000610 HMMPfam hit to PF00700, Bacterial flagellin C-terminus, score 2.8e-15 216591000611 HMMPfam hit to PF00669, Bacterial flagellin N-terminus, score 2.9e-63 216591000612 30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270 216591000613 HMMPfam hit to PF01165, Ribosomal protein S21, score 3.6e-31 216591000614 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 216591000615 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591000616 N-terminal plug; other site 216591000617 ligand-binding site [chemical binding]; other site 216591000618 HMMPfam hit to PF00593, TonB dependent receptor, score 4e-23 216591000619 PS01156 TonB-dependent receptor proteins signature 2. 216591000620 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000621 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 8.6e-15 216591000622 Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182 216591000623 PepSY-associated TM helix; Region: PepSY_TM_3; pfam13706 216591000624 PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703 216591000625 HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.18 216591000626 5 probable transmembrane helices predicted for BCAL0117 by TMHMM2.0 at aa 25-47, 161-183, 223-245, 295-317 and 375-397 216591000627 HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.1 216591000628 HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.0053 216591000629 Methyladenine glycosylase; Region: Adenine_glyco; pfam03352 216591000630 HMMPfam hit to PF03352, Methyladenine glycosylase, score 6.7e-93 216591000631 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 216591000632 HMMPfam hit to PF01869, BadF/BadG/BcrA/BcrD ATPase family, score 3.5e-26 216591000633 putative hydrolase; Provisional; Region: PRK10976 216591000634 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591000635 active site 216591000636 motif I; other site 216591000637 motif II; other site 216591000638 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915 216591000639 HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 7.1e-06 216591000640 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.00014 216591000641 PS01228 Hypothetical cof family signature 1. 216591000642 HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 7.2e-65 216591000643 Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333 216591000644 amphipathic channel; other site 216591000645 Asn-Pro-Ala signature motifs; other site 216591000646 6 probable transmembrane helices predicted for BCAL0121 by TMHMM2.0 at aa 7-29, 34-56, 83-105, 130-152, 159-181 and 208-230 216591000647 HMMPfam hit to PF00230, Major intrinsic protein, score 1.1e-41 216591000648 PS00221 MIP family signature. 216591000649 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000650 H-NS histone family; Region: Histone_HNS; pfam00816 216591000651 HMMPfam hit to PF00816, H-NS histone family, score 1.5e-18 216591000652 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591000653 This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802 216591000654 putative ADP-binding pocket [chemical binding]; other site 216591000655 HMMPfam hit to PF00534, Glycosyl transferases group, score 4e-22 216591000656 transcriptional activator FlhD; Provisional; Region: PRK02909 216591000657 HMMPfam hit to PF05247, Flagellar transcriptional activator (FlhD), score 4.9e-47 216591000658 transcriptional activator FlhC; Provisional; Region: PRK12722 216591000659 HMMPfam hit to PF05280, Flagellar transcriptional activator (FlhC), score 7.2e-129 216591000660 Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291 216591000661 flagellar motor protein MotA; Validated; Region: PRK09110 216591000662 4 probable transmembrane helices predicted for BCAL0126 by TMHMM2.0 at aa 2-24, 29-51, 171-190 and 205-227 216591000663 PS01307 Flagellar motor protein motA family signature. 216591000664 Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677 216591000665 Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360 216591000666 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591000667 ligand binding site [chemical binding]; other site 216591000668 1 probable transmembrane helix predicted for BCAL0127 by TMHMM2.0 at aa 28-47 216591000669 HMMPfam hit to PF00691, OmpA family, score 3.2e-26 216591000670 Response regulator receiver domain; Region: Response_reg; pfam00072 216591000671 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591000672 active site 216591000673 phosphorylation site [posttranslational modification] 216591000674 intermolecular recognition site; other site 216591000675 dimerization interface [polypeptide binding]; other site 216591000676 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.7e-30 216591000677 Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088 216591000678 putative binding surface; other site 216591000679 active site 216591000680 CheY binding; Region: CheY-binding; pfam09078 216591000681 Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895 216591000682 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591000683 ATP binding site [chemical binding]; other site 216591000684 Mg2+ binding site [ion binding]; other site 216591000685 G-X-G motif; other site 216591000686 CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731 216591000687 HMMPfam hit to PF01627, Hpt domain, score 4.6e-17 216591000688 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 216591000689 HMMPfam hit to PF02895, Signal transducing histidine kinase, hom, score 2.7e-24 216591000690 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 2.6e-26 216591000691 HMMPfam hit to PF01584, CheW-like domain, score 1.8e-24 216591000692 CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256 216591000693 HMMPfam hit to PF01584, CheW-like domain, score 5.9e-35 216591000694 Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729 216591000695 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181 216591000696 dimer interface [polypeptide binding]; other site 216591000697 ligand binding site [chemical binding]; other site 216591000698 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591000699 dimerization interface [polypeptide binding]; other site 216591000700 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591000701 dimer interface [polypeptide binding]; other site 216591000702 putative CheW interface [polypeptide binding]; other site 216591000703 2 probable transmembrane helices predicted for BCAL0131 by TMHMM2.0 at aa 10-32 and 190-212 216591000704 HMMPfam hit to PF00672, HAMP domain, score 6.7e-13 216591000705 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 3.8e-99 216591000706 chemotaxis methyltransferase CheR; Provisional; Region: PRK10611 216591000707 CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705 216591000708 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591000709 HMMPfam hit to PF01739, CheR methyltransferase, SAM binding domain, score 1.8e-72 216591000710 chemoreceptor glutamine deamidase CheD; Provisional; Region: PRK13489 216591000711 HMMPfam hit to PF03975, CheD, score 9.6e-40 216591000712 chemotaxis-specific methylesterase; Provisional; Region: PRK00742 216591000713 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591000714 active site 216591000715 phosphorylation site [posttranslational modification] 216591000716 intermolecular recognition site; other site 216591000717 dimerization interface [polypeptide binding]; other site 216591000718 CheB methylesterase; Region: CheB_methylest; pfam01339 216591000719 HMMPfam hit to PF00072, Response regulator receiver domain, score 3.9e-30 216591000720 HMMPfam hit to PF01339, CheB methylesterase, score 5.1e-107 216591000721 chemotaxis regulatory protein CheY; Provisional; Region: PRK10610 216591000722 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591000723 active site 216591000724 phosphorylation site [posttranslational modification] 216591000725 intermolecular recognition site; other site 216591000726 dimerization interface [polypeptide binding]; other site 216591000727 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.1e-43 216591000728 chemotaxis regulator CheZ; Provisional; Region: PRK11166 216591000729 HMMPfam hit to PF04344, Chemotaxis phosphatase, CheZ, score 3.2e-69 216591000730 Protein of unknown function (DUF2844); Region: DUF2844; pfam11005 216591000731 Gly/Ala/Ser-rich lipoprotein (pseudogene);CDS contains a nonsense mutation (amber) after codon 47. Similar to Burkholderia pseudomallei Gly/Ala/Ser-rich lipoprotein UniProt:Q63PS6 (EMBL:BX571965) (434 aa) fasta scores: E()=2.6e-79, 55.909% id in 440 aa 216591000732 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591000733 Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588 216591000734 dimer interface [polypeptide binding]; other site 216591000735 HMMPfam hit to PF06983, 3-demethylubiquinone-9 3-methyltransfera, score 2e-71 216591000736 flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702 216591000737 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257 216591000738 HMMPfam hit to PF01312, FlhB HrpN YscU SpaS Family, score 2.9e-140 216591000739 4 probable transmembrane helices predicted for BCAL0140 by TMHMM2.0 at aa 33-55, 94-116, 146-165 and 185-207 216591000740 flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012 216591000741 FHIPEP family; Region: FHIPEP; pfam00771 216591000742 7 probable transmembrane helices predicted for BCAL0141 by TMHMM2.0 at aa 21-40, 44-66, 78-100, 120-142, 211-233, 253-275 and 296-318 216591000743 HMMPfam hit to PF00771, FHIPEP family, score 0 216591000744 PS00994 Bacterial export FHIPEP family signature. 216591000745 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 216591000746 flagellar biosynthetic protein FlhF; Region: FlhF; TIGR03499 216591000747 SRP54-type protein, GTPase domain; Region: SRP54; smart00962 216591000748 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 216591000749 HMMPfam hit to PF00448, SRP54-type protein, GTPase domain, score 2.6e-23 216591000750 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000751 Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455 216591000752 FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038 216591000753 P-loop; other site 216591000754 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000755 flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986 216591000756 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591000757 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 216591000758 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591000759 DNA binding residues [nucleotide binding] 216591000760 HMMPfam hit to PF04542, Sigma-70 region, score 1.9e-18 216591000761 PS00715 Sigma-70 factors family signature 1. 216591000762 HMMPfam hit to PF04539, Sigma-70 region, score 2.1e-09 216591000763 HMMPfam hit to PF08281, Sigma-70, region, score 5.4e-07 216591000764 HMMPfam hit to PF04545, Sigma-70, region, score 7.1e-17 216591000765 Predicted helix-turn-helix motif with score 1243.000, SD 3.42 at aa 202-223, sequence LNLREIGAVLEVSESRVCQLHS 216591000766 PS00716 Sigma-70 factors family signature 2. 216591000767 S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476 216591000768 S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401 216591000769 homotetramer interface [polypeptide binding]; other site 216591000770 ligand binding site [chemical binding]; other site 216591000771 catalytic site [active] 216591000772 NAD binding site [chemical binding]; other site 216591000773 HMMPfam hit to PF05221, S-adenosyl-L-homocysteine hydrolase, score 3.7e-193 216591000774 PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 216591000775 HMMPfam hit to PF00670, S-adenosyl-L-homocysteine hydrolase, NA, score 1.3e-111 216591000776 PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 216591000777 Predicted membrane protein [Function unknown]; Region: COG1950 216591000778 HMMPfam hit to PF04020, Membrane protein of unknown function, score 6.6e-37 216591000779 4 probable transmembrane helices predicted for BCAL0146 by TMHMM2.0 at aa 4-26, 33-55, 59-81 and 88-110 216591000780 Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537 216591000781 FAD binding site [chemical binding]; other site 216591000782 HMMPfam hit to PF02219, Methylenetetrahydrofolate reductase, score 1.4e-107 216591000783 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154 216591000784 Amidase; Region: Amidase; cl11426 216591000785 HMMPfam hit to PF01425, Amidase, score 2.4e-79 216591000786 PS00571 Amidases signature. 216591000787 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000788 Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412 216591000789 HMMPfam hit to PF01738, Dienelactone hydrolase family, score 2.7e-68 216591000790 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 216591000791 FMN binding site [chemical binding]; other site 216591000792 substrate binding site [chemical binding]; other site 216591000793 putative catalytic residue [active] 216591000794 HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 1.9e-84 216591000795 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591000796 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 216591000797 dimerization interface [polypeptide binding]; other site 216591000798 ligand binding site [chemical binding]; other site 216591000799 HMMPfam hit to PF01094, Receptor family ligand binding region, score 1.5e-68 216591000800 12 probable transmembrane helices predicted for BCAL0152 by TMHMM2.0 at aa 42-64, 79-101, 108-125, 129-148, 169-191, 195-217, 237-256, 266-288, 300-322, 327-349, 362-384 and 389-411 216591000801 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.5e-16 216591000802 Pyridoxamine 5'-phosphate oxidase; Region: Pyrid_oxidase_2; pfam13883 216591000803 Protein of unknown function (DUF2470); Region: DUF2470; pfam10615 216591000804 HMMPfam hit to PF01243, Pyridoxamine 5'-phosphate oxidase, score 1.2e-10 216591000805 H-NS histone family; Region: Histone_HNS; pfam00816 216591000806 Domain in histone-like proteins of HNS family; Region: HNS; smart00528 216591000807 HMMPfam hit to PF00816, H-NS histone family, score 3.9e-20 216591000808 Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053 216591000809 Cation efflux family; Region: Cation_efflux; pfam01545 216591000810 HMMPfam hit to PF01545, Cation efflux family, score 3.6e-73 216591000811 3 probable transmembrane helices predicted for BCAL0155 by TMHMM2.0 at aa 21-43, 88-107 and 114-136 216591000812 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591000813 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591000814 putative DNA binding site [nucleotide binding]; other site 216591000815 putative Zn2+ binding site [ion binding]; other site 216591000816 AsnC family; Region: AsnC_trans_reg; pfam01037 216591000817 HMMPfam hit to PF01037, AsnC family, score 8.9e-33 216591000818 PS00519 Bacterial regulatory proteins, asnC family signature. 216591000819 Predicted helix-turn-helix motif with score 1034.000, SD 2.71 at aa 24-45, sequence RSVQEISDQVGLSSTPCWRRIK 216591000820 active site 216591000821 catalytic site [active] 216591000822 substrate binding site [chemical binding]; other site 216591000823 DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012 216591000824 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 216591000825 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 1.8e-37 216591000826 Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797 216591000827 Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330 216591000828 HMMPfam hit to PF03330, Rare lipoprotein A (RlpA)-like double-psi be, score 7.4e-40 216591000829 Predicted methyltransferases [General function prediction only]; Region: COG0313 216591000830 Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648 216591000831 putative SAM binding site [chemical binding]; other site 216591000832 putative homodimer interface [polypeptide binding]; other site 216591000833 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 3.1e-43 216591000834 PS01296 Uncharacterized protein family UPF0011 signature. 216591000835 hypothetical protein; Provisional; Region: PRK14673 216591000836 HMMPfam hit to PF02021, Uncharacterised protein family UPF0102, score 3e-26 216591000837 Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006 216591000838 active site 216591000839 dimer interface [polypeptide binding]; other site 216591000840 outer membrane lipoprotein; Provisional; Region: PRK11023 216591000841 BON domain; Region: BON; pfam04972 216591000842 BON domain; Region: BON; cl02771 216591000843 1 probable transmembrane helix predicted for BCAL0163 by TMHMM2.0 at aa 21-43 216591000844 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000845 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 5.4e-13 216591000846 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 0.00011 216591000847 Cytochrome c; Region: Cytochrom_C; cl11414 216591000848 1 probable transmembrane helix predicted for BCAL0164 by TMHMM2.0 at aa 13-35 216591000849 HMMPfam hit to PF00034, Cytochrome c, score 6.5e-07 216591000850 PS00190 Cytochrome c family heme-binding site signature. 216591000851 BcenGI2 216591000852 Replication initiator protein A; Region: RPA; pfam10134 216591000853 Predicted helix-turn-helix motif with score 1060.000, SD 2.80 at aa 221-242, sequence RRIYELACKHCGNQPTWKSSIA 216591000854 putative transposase OrfB; Reviewed; Region: PHA02517 216591000855 HTH-like domain; Region: HTH_21; pfam13276 216591000856 Integrase core domain; Region: rve; pfam00665 216591000857 Integrase core domain; Region: rve_2; pfam13333 216591000858 HMMPfam hit to PF00665, Integrase core domain, score 5.1e-42 216591000859 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591000860 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591000861 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591000862 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591000863 Predicted helix-turn-helix motif with score 1703.000, SD 4.99 at aa 20-41, sequence EAIRAVARTHGLSHSTVSQWYA 216591000864 hypothetical protein (fragment) 216591000865 conjugal transfer relaxosome component TraJ; Provisional; Region: PRK13877 216591000866 conjugal transfer protein TrbJ; Provisional; Region: PRK13879 216591000867 P-type conjugative transfer protein TrbL; Region: TrbL_P; TIGR02783 216591000868 8 probable transmembrane helices predicted for BCAL0174 by TMHMM2.0 at aa 68-87, 107-129, 150-172, 218-240, 242-264, 274-296, 303-325 and 335-357 216591000869 HMMPfam hit to PF04610, TrbL/VirB6 plasmid conjugal transfer protein, score 1e-12 216591000870 Toxin of toxin-antitoxin type 1 system; Region: plasmid_Toxin; pfam12703 216591000871 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 216591000872 non-specific DNA binding site [nucleotide binding]; other site 216591000873 salt bridge; other site 216591000874 sequence-specific DNA binding site [nucleotide binding]; other site 216591000875 Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877 216591000876 Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338 216591000877 HMMPfam hit to PF02086, D12 class N6 adenine-specific DNA met, score 0.0013 216591000878 PS00092 N-6 Adenine-specific DNA methylases signature. 216591000879 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from archaea and bacteria; Region: NTP-PPase_COG4997; cd11532 216591000880 metal binding site [ion binding]; metal-binding site 216591000881 Predicted helix-turn-helix motif with score 1098.000, SD 2.93 at aa 115-136, sequence TTVTDLARALEICLRQISSSLS 216591000882 lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176 216591000883 4 probable transmembrane helices predicted for BCAL0180 by TMHMM2.0 at aa 94-116, 131-153, 166-188 and 192-214 216591000884 HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228 216591000885 nucleotide binding site/active site [active] 216591000886 HIT family signature motif; other site 216591000887 catalytic residue [active] 216591000888 integrase; Provisional; Region: int; PHA02601 216591000889 Rci recombinase, C-terminal catalytic domain. Rci enzymes are found in IncI1 incompatibility group plasmids such as R64. These recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain...; Region: INT_Rci; cd00796 216591000890 catalytic residues [active] 216591000891 Int/Topo IB signature motif; other site 216591000892 HMMPfam hit to PF00589, Phage integrase family, score 3e-28 216591000893 glucarate dehydratase; Region: glucar-dehydr; TIGR03247 216591000894 D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323 216591000895 active site 216591000896 tetramer interface [polypeptide binding]; other site 216591000897 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591000898 D-galactonate transporter; Region: 2A0114; TIGR00893 216591000899 putative substrate translocation pore; other site 216591000900 10 probable transmembrane helices predicted for BCAL0184 by TMHMM2.0 at aa 23-45, 60-82, 95-117, 179-201, 254-276, 291-313, 325-347, 351-373, 386-408 and 418-440 216591000901 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.2e-55 216591000902 LysR family transcriptional regulator; Provisional; Region: PRK14997 216591000903 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591000904 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591000905 putative effector binding pocket; other site 216591000906 dimerization interface [polypeptide binding]; other site 216591000907 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.7e-44 216591000908 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000909 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.5e-18 216591000910 PS00044 Bacterial regulatory proteins, lysR family signature. 216591000911 Predicted helix-turn-helix motif with score 1533.000, SD 4.41 at aa 21-42, sequence GSMSAAARRLDLPKSTVSKRVA 216591000912 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591000913 GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057 216591000914 C-terminal domain interface [polypeptide binding]; other site 216591000915 GSH binding site (G-site) [chemical binding]; other site 216591000916 dimer interface [polypeptide binding]; other site 216591000917 C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776 216591000918 N-terminal domain interface [polypeptide binding]; other site 216591000919 dimer interface [polypeptide binding]; other site 216591000920 substrate binding pocket (H-site) [chemical binding]; other site 216591000921 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 0.012 216591000922 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 1.3e-05 216591000923 Uncharacterized protein conserved in bacteria (DUF2239); Region: DUF2239; pfam09998 216591000924 Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3670 216591000925 Retinal pigment epithelial membrane protein; Region: RPE65; pfam03055 216591000926 HMMPfam hit to PF03055, Retinal pigment epithelial membrane protein, score 9e-87 216591000927 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 216591000928 FtsX-like permease family; Region: FtsX; pfam02687 216591000929 HMMPfam hit to PF02687, Predicted permease, score 1.9e-29 216591000930 4 probable transmembrane helices predicted for BCAL0189 by TMHMM2.0 at aa 17-39, 259-281, 301-323 and 349-371 216591000931 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000932 HMMPfam hit to PF02687, Predicted permease, score 2.2e-22 216591000933 4 probable transmembrane helices predicted for BCAL0190 by TMHMM2.0 at aa 21-43, 256-278, 299-321 and 349-371 216591000934 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 216591000935 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 216591000936 Walker A/P-loop; other site 216591000937 ATP binding site [chemical binding]; other site 216591000938 Q-loop/lid; other site 216591000939 ABC transporter signature motif; other site 216591000940 Walker B; other site 216591000941 D-loop; other site 216591000942 H-loop/switch region; other site 216591000943 HMMPfam hit to PF00005, ABC transporter, score 4e-62 216591000944 PS00211 ABC transporters family signature. 216591000945 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000946 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 216591000947 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591000948 HMMPfam hit to PF00529, HlyD family secretion protein, score 5.5e-05 216591000949 1 probable transmembrane helix predicted for BCAL0192 by TMHMM2.0 at aa 25-47 216591000950 1 probable transmembrane helix predicted for BCAL0193 by TMHMM2.0 at aa 5-27 216591000951 Ub domain fused to Mut7-C; Region: Ub-Mut7C; pfam14451 216591000952 Uncharacterized conserved protein [Function unknown]; Region: COG1656 216591000953 Protein of unknown function DUF82; Region: DUF82; pfam01927 216591000954 HMMPfam hit to PF01927, Protein of unknown function DUF82, score 1.8e-30 216591000955 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084 216591000956 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 216591000957 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 2.3e-44 216591000958 HMMPfam hit to PF03807, NADP oxidoreductase coenzyme F420-depen, score 0.00017 216591000959 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591000960 6 probable transmembrane helices predicted for BCAL0195 by TMHMM2.0 at aa 5-27, 40-62, 67-86, 121-143, 153-175 and 187-209 216591000961 HMMPfam hit to PF01810, LysE type translocator, score 4.5e-32 216591000962 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591000963 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591000964 12 probable transmembrane helices predicted for BCAL0196 by TMHMM2.0 at aa 20-42, 62-84, 91-110, 115-137, 149-171, 175-197, 226-248, 261-283, 296-318, 322-344, 365-387 and 391-413 216591000965 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4e-27 216591000966 PS00136 Serine proteases, subtilase family, aspartic acid active site. 216591000967 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591000968 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591000969 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591000970 dimerization interface [polypeptide binding]; other site 216591000971 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.4e-21 216591000972 PS00044 Bacterial regulatory proteins, lysR family signature. 216591000973 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.9e-36 216591000974 Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047 216591000975 HMMPfam hit to PF03922, OmpW family, score 6.6e-12 216591000976 Protein of unknown function (DUF2957); Region: DUF2957; pfam11170 216591000977 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000978 Protein of unknown function (DUF2957); Region: DUF2957; pfam11170 216591000979 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000980 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591000981 N-acetyl-gamma-glutamyl-phosphate reductase; Provisional; Region: PRK11863 216591000982 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 216591000983 PS00017 ATP/GTP-binding site motif A (P-loop). 216591000984 HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindin, score 2.8e-06 216591000985 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 216591000986 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591000987 HMMPfam hit to PF00258, Flavodoxin, score 0.0005 216591000988 PS00201 Flavodoxin signature. 216591000989 PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865 216591000990 substrate binding site [chemical binding]; other site 216591000991 HMMPfam hit to PF01161, Phosphatidylethanolamine-binding protein, score 1.3e-06 216591000992 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 216591000993 active site 216591000994 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 3.9e-17 216591000995 bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232 216591000996 Malic enzyme, N-terminal domain; Region: malic; pfam00390 216591000997 NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311 216591000998 putative NAD(P) binding site [chemical binding]; other site 216591000999 Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280 216591001000 HMMPfam hit to PF00390, Malic enzyme, N-terminal domain, score 3.9e-77 216591001001 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001002 HMMPfam hit to PF03949, Malic enzyme, NAD binding domain, score 1.6e-127 216591001003 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001004 HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 2.1e-108 216591001005 indolepyruvate ferredoxin oxidoreductase; Validated; Region: PRK09193 216591001006 Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034 216591001007 dimer interface [polypeptide binding]; other site 216591001008 PYR/PP interface [polypeptide binding]; other site 216591001009 TPP binding site [chemical binding]; other site 216591001010 substrate binding site [chemical binding]; other site 216591001011 Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as...; Region: TPP_IOR_alpha; cd02008 216591001012 TPP-binding site; other site 216591001013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014 216591001014 Sfi1 spindle body protein; Region: Sfi1; pfam08457 216591001015 HMMPfam hit to PF01558, Pyruvate ferredoxin/flavodoxin oxidoreductas, score 1.1e-05 216591001016 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [Amino acid transport and metabolism / General function prediction only]; Region: COG3185 216591001017 N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342 216591001018 dimer interface [polypeptide binding]; other site 216591001019 C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250 216591001020 active site 216591001021 Fe binding site [ion binding]; other site 216591001022 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 1.1e-11 216591001023 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591001024 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591001025 putative DNA binding site [nucleotide binding]; other site 216591001026 putative Zn2+ binding site [ion binding]; other site 216591001027 AsnC family; Region: AsnC_trans_reg; pfam01037 216591001028 Predicted helix-turn-helix motif with score 1496.000, SD 4.28 at aa 23-44, sequence LSNQEIAERVNLSPSPCLRRIR 216591001029 PS00519 Bacterial regulatory proteins, asnC family signature. 216591001030 HMMPfam hit to PF01037, AsnC family, score 2.7e-24 216591001031 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 216591001032 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591001033 Coenzyme A binding pocket [chemical binding]; other site 216591001034 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 5.8e-09 216591001035 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591001036 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591001037 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 7.4e-12 216591001038 Predicted helix-turn-helix motif with score 1303.000, SD 3.62 at aa 32-53, sequence TSMSDLATASGTSKARLYHYYE 216591001039 Domain of unknown function (DUF1835); Region: DUF1835; pfam08874 216591001040 Protein of unknown function; Region: DUF3658; pfam12395 216591001041 phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160 216591001042 NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214 216591001043 FAD binding pocket [chemical binding]; other site 216591001044 FAD binding motif [chemical binding]; other site 216591001045 phosphate binding motif [ion binding]; other site 216591001046 beta-alpha-beta structure motif; other site 216591001047 NAD(p) ribose binding residues [chemical binding]; other site 216591001048 NAD binding pocket [chemical binding]; other site 216591001049 NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site 216591001050 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591001051 catalytic loop [active] 216591001052 iron binding site [ion binding]; other site 216591001053 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 7.4e-17 216591001054 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 8.6e-15 216591001055 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 2.4e-14 216591001056 Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151 216591001057 phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159 216591001058 HMMPfam hit to PF01883, Domain of unknown function DUF59, score 6.5e-15 216591001059 Phenylacetic acid catabolic protein; Region: PaaA_PaaC; pfam05138 216591001060 HMMPfam hit to PF05138, Phenylacetic acid catabolic protein, score 9.9e-52 216591001061 phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781 216591001062 HMMPfam hit to PF06243, Phenylacetic acid degradation B, score 8.5e-71 216591001063 phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778 216591001064 phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156 216591001065 HMMPfam hit to PF05138, Phenylacetic acid catabolic protein, score 2.9e-146 216591001066 SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE. The P. bryantii XynE gene is located in a xylanase gene cluster. SGNH hydrolases are a diverse family of lipases and esterases; Region: XynE_like; cd01830 216591001067 active site 216591001068 catalytic triad [active] 216591001069 oxyanion hole [active] 216591001070 HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 1.5e-22 216591001071 elongation factor Tu; Reviewed; Region: PRK00049 216591001072 Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884 216591001073 G1 box; other site 216591001074 GEF interaction site [polypeptide binding]; other site 216591001075 GTP/Mg2+ binding site [chemical binding]; other site 216591001076 Switch I region; other site 216591001077 G2 box; other site 216591001078 G3 box; other site 216591001079 Switch II region; other site 216591001080 G4 box; other site 216591001081 G5 box; other site 216591001082 EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697 216591001083 Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707 216591001084 Antibiotic Binding Site [chemical binding]; other site 216591001085 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 7e-102 216591001086 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001087 PS00301 GTP-binding elongation factors signature. 216591001088 HMMPfam hit to PF03144, Elongation factor Tu domain, score 7.5e-26 216591001089 HMMPfam hit to PF03143, Elongation factor Tu C-terminal domain, score 2.5e-62 216591001090 preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740 216591001091 3 probable transmembrane helices predicted for BCAL0220 by TMHMM2.0 at aa 15-37, 49-71 and 91-110 216591001092 HMMPfam hit to PF00584, SecE/Sec61-gamma subunits of protein translo, score 3.4e-17 216591001093 transcription antitermination protein NusG; Validated; Region: nusG; PRK05609 216591001094 Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891 216591001095 putative homodimer interface [polypeptide binding]; other site 216591001096 NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091 216591001097 heterodimer interface [polypeptide binding]; other site 216591001098 homodimer interface [polypeptide binding]; other site 216591001099 HMMPfam hit to PF02357, Transcription termination factor nusG, score 1.4e-54 216591001100 HMMPfam hit to PF00467, KOW motif, score 7.1e-10 216591001101 PS01014 Transcription termination factor nusG signature. 216591001102 50S ribosomal protein L11; Validated; Region: rplK; PRK00140 216591001103 Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349 216591001104 23S rRNA interface [nucleotide binding]; other site 216591001105 L7/L12 interface [polypeptide binding]; other site 216591001106 putative thiostrepton binding site; other site 216591001107 L25 interface [polypeptide binding]; other site 216591001108 Ribosomal protein L1. The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA. In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403 216591001109 mRNA/rRNA interface [nucleotide binding]; other site 216591001110 HMMPfam hit to PF00687, Ribosomal protein L1p/L10e family, score 1.5e-122 216591001111 PS01199 Ribosomal protein L1 signature. 216591001112 Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797 216591001113 23S rRNA interface [nucleotide binding]; other site 216591001114 Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site 216591001115 HMMPfam hit to PF00466, Ribosomal protein L10, score 3.8e-20 216591001116 Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387 216591001117 peripheral dimer interface [polypeptide binding]; other site 216591001118 core dimer interface [polypeptide binding]; other site 216591001119 L10 interface [polypeptide binding]; other site 216591001120 L11 interface [polypeptide binding]; other site 216591001121 putative EF-Tu interaction site [polypeptide binding]; other site 216591001122 putative EF-G interaction site [polypeptide binding]; other site 216591001123 HMMPfam hit to PF00542, Ribosomal protein L7/L12 C-terminal dom, score 3.4e-38 216591001124 DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405 216591001125 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585 216591001126 RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561 216591001127 RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561 216591001128 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653 216591001129 RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562 216591001130 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653 216591001131 RPB3 interaction site [polypeptide binding]; other site 216591001132 RPB1 interaction site [polypeptide binding]; other site 216591001133 RPB11 interaction site [polypeptide binding]; other site 216591001134 RPB10 interaction site [polypeptide binding]; other site 216591001135 HMMPfam hit to PF04563, RNA polymerase beta subunit, score 2e-28 216591001136 HMMPfam hit to PF04561, RNA polymerase Rpb2, domain, score 4.9e-06 216591001137 HMMPfam hit to PF04565, RNA polymerase Rpb2, domain, score 1.7e-45 216591001138 HMMPfam hit to PF00562, RNA polymerase Rpb2, domain, score 3.2e-184 216591001139 PS01166 RNA polymerases beta chain signature. 216591001140 HMMPfam hit to PF04560, RNA polymerase Rpb2, domain, score 1.3e-47 216591001141 DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086 216591001142 RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997 216591001143 RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663 216591001144 RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983 216591001145 RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000 216591001146 Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429 216591001147 Rpb1 - Rpb6 interaction site [polypeptide binding]; other site 216591001148 Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655 216591001149 DNA binding site [nucleotide binding] 216591001150 Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site 216591001151 ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389 216591001152 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 216591001153 ATP binding site [chemical binding]; other site 216591001154 putative Mg++ binding site [ion binding]; other site 216591001155 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591001156 nucleotide binding region [chemical binding]; other site 216591001157 ATP-binding site [chemical binding]; other site 216591001158 This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956 216591001159 HRDC domain; Region: HRDC; pfam00570 216591001160 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 3.6e-27 216591001161 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.8e-26 216591001162 HMMPfam hit to PF00570, HRDC domain, score 1.6e-20 216591001163 S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368 216591001164 S17 interaction site [polypeptide binding]; other site 216591001165 S8 interaction site; other site 216591001166 16S rRNA interaction site [nucleotide binding]; other site 216591001167 streptomycin interaction site [chemical binding]; other site 216591001168 23S rRNA interaction site [nucleotide binding]; other site 216591001169 aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site 216591001170 HMMPfam hit to PF00164, Ribosomal protein S12, score 2.8e-76 216591001171 PS00055 Ribosomal protein S12 signature. 216591001172 30S ribosomal protein S7; Validated; Region: PRK05302 216591001173 HMMPfam hit to PF00177, Ribosomal protein S7p/S5e, score 5.6e-82 216591001174 PS00052 Ribosomal protein S7 signature. 216591001175 elongation factor G; Reviewed; Region: PRK00007 216591001176 Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886 216591001177 G1 box; other site 216591001178 putative GEF interaction site [polypeptide binding]; other site 216591001179 GTP/Mg2+ binding site [chemical binding]; other site 216591001180 Switch I region; other site 216591001181 G2 box; other site 216591001182 G3 box; other site 216591001183 Switch II region; other site 216591001184 G4 box; other site 216591001185 G5 box; other site 216591001186 EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088 216591001187 EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434 216591001188 EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G. Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713 216591001189 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.2e-110 216591001190 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001191 PS00301 GTP-binding elongation factors signature. 216591001192 HMMPfam hit to PF03144, Elongation factor Tu domain, score 3.2e-21 216591001193 HMMPfam hit to PF03764, Elongation factor G, domain IV, score 3e-70 216591001194 HMMPfam hit to PF00679, Elongation factor G C-terminus, score 1.2e-50 216591001195 elongation factor Tu; Reviewed; Region: PRK00049 216591001196 Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884 216591001197 G1 box; other site 216591001198 GEF interaction site [polypeptide binding]; other site 216591001199 GTP/Mg2+ binding site [chemical binding]; other site 216591001200 Switch I region; other site 216591001201 G2 box; other site 216591001202 G3 box; other site 216591001203 Switch II region; other site 216591001204 G4 box; other site 216591001205 G5 box; other site 216591001206 EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697 216591001207 Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707 216591001208 Antibiotic Binding Site [chemical binding]; other site 216591001209 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 7e-102 216591001210 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001211 PS00301 GTP-binding elongation factors signature. 216591001212 HMMPfam hit to PF03144, Elongation factor Tu domain, score 7.5e-26 216591001213 HMMPfam hit to PF03143, Elongation factor Tu C-terminal domain, score 2.5e-62 216591001214 30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596 216591001215 HMMPfam hit to PF00338, Ribosomal protein S10p/S20e, score 2.3e-51 216591001216 PS00361 Ribosomal protein S10 signature. 216591001217 50S ribosomal protein L3; Validated; Region: rplC; PRK00001 216591001218 HMMPfam hit to PF00297, Ribosomal protein L3, score 1.1e-80 216591001219 PS00474 Ribosomal protein L3 signature. 216591001220 50S ribosomal protein L4; Provisional; Region: rplD; PRK05319 216591001221 HMMPfam hit to PF00573, Ribosomal protein L4/L1 family, score 1.9e-46 216591001222 50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738 216591001223 HMMPfam hit to PF00276, Ribosomal protein L23, score 9.3e-28 216591001224 50S ribosomal protein L2; Validated; Region: rplB; PRK09374 216591001225 Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181 216591001226 Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947 216591001227 HMMPfam hit to PF00181, Ribosomal Proteins L2, RNA binding dom, score 2.3e-47 216591001228 HMMPfam hit to PF03947, Ribosomal Proteins L2, C-terminal doma, score 8.1e-86 216591001229 PS00467 Ribosomal protein L2 signature. 216591001230 30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357 216591001231 HMMPfam hit to PF00203, Ribosomal protein S19, score 3.5e-52 216591001232 PS00323 Ribosomal protein S19 signature. 216591001233 Ribosomal protein L22/L17e. L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit. It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336 216591001234 putative translocon binding site; other site 216591001235 protein-rRNA interface [nucleotide binding]; other site 216591001236 HMMPfam hit to PF00237, Ribosomal protein L22p/L17e, score 1.1e-44 216591001237 PS00464 Ribosomal protein L22 signature. 216591001238 30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310 216591001239 K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3 is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel. The KH...; Region: 30S_S3_KH; cd02412 216591001240 G-X-X-G motif; other site 216591001241 Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189 216591001242 HMMPfam hit to PF00417, Ribosomal protein S3, N-terminal domai, score 1.3e-26 216591001243 HMMPfam hit to PF07650, KH domain, score 3.2e-22 216591001244 HMMPfam hit to PF00189, Ribosomal protein S3, C-terminal domai, score 1.4e-51 216591001245 PS00548 Ribosomal protein S3 signature. 216591001246 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001247 Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433 216591001248 23S rRNA interface [nucleotide binding]; other site 216591001249 5S rRNA interface [nucleotide binding]; other site 216591001250 putative antibiotic binding site [chemical binding]; other site 216591001251 L25 interface [polypeptide binding]; other site 216591001252 L27 interface [polypeptide binding]; other site 216591001253 HMMPfam hit to PF00252, Ribosomal protein L16, score 2.6e-86 216591001254 PS00586 Ribosomal protein L16 signature 1. 216591001255 Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals. L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427 216591001256 23S rRNA interface [nucleotide binding]; other site 216591001257 putative translocon interaction site; other site 216591001258 signal recognition particle (SRP54) interaction site; other site 216591001259 L23 interface [polypeptide binding]; other site 216591001260 trigger factor interaction site; other site 216591001261 HMMPfam hit to PF00831, Ribosomal L29 protein, score 3.2e-21 216591001262 PS00579 Ribosomal protein L29 signature. 216591001263 30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610 216591001264 HMMPfam hit to PF00366, Ribosomal protein S17, score 1.8e-35 216591001265 PS00056 Ribosomal protein S17 signature. 216591001266 50S ribosomal protein L14; Validated; Region: rplN; PRK05483 216591001267 HMMPfam hit to PF00238, Ribosomal protein L14p/L23e, score 6.6e-76 216591001268 PS00049 Ribosomal protein L14 signature. 216591001269 50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004 216591001270 KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089 216591001271 RNA binding site [nucleotide binding]; other site 216591001272 HMMPfam hit to PF00467, KOW motif, score 7.1e-06 216591001273 PS01108 Ribosomal protein L24 signature. 216591001274 50S ribosomal protein L5; Validated; Region: rplE; PRK00010 216591001275 Ribosomal protein L5; Region: Ribosomal_L5; pfam00281 216591001276 ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673 216591001277 HMMPfam hit to PF00281, Ribosomal protein L5, score 5.8e-31 216591001278 PS00358 Ribosomal protein L5 signature. 216591001279 HMMPfam hit to PF00673, ribosomal L5P family C-terminus, score 5.2e-50 216591001280 30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881 216591001281 HMMPfam hit to PF00253, Ribosomal protein S14p/S29e, score 1.4e-20 216591001282 30S ribosomal protein S8; Validated; Region: rpsH; PRK00136 216591001283 HMMPfam hit to PF00410, Ribosomal protein S8, score 2.2e-64 216591001284 PS00053 Ribosomal protein S8 signature. 216591001285 PS00294 Prenyl group binding site (CAAX box). 216591001286 50S ribosomal protein L6; Validated; Region: rplF; PRK05498 216591001287 Ribosomal protein L6; Region: Ribosomal_L6; pfam00347 216591001288 Ribosomal protein L6; Region: Ribosomal_L6; pfam00347 216591001289 HMMPfam hit to PF00347, Ribosomal protein L6, score 6.7e-13 216591001290 HMMPfam hit to PF00347, Ribosomal protein L6, score 7.6e-32 216591001291 PS00525 Ribosomal protein L6 signature 1. 216591001292 Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432 216591001293 5S rRNA interface [nucleotide binding]; other site 216591001294 L27 interface [polypeptide binding]; other site 216591001295 23S rRNA interface [nucleotide binding]; other site 216591001296 L5 interface [polypeptide binding]; other site 216591001297 HMMPfam hit to PF00861, Ribosomal L18p/L5e family, score 3.8e-37 216591001298 30S ribosomal protein S5; Validated; Region: rpsE; PRK00550 216591001299 Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333 216591001300 Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719 216591001301 HMMPfam hit to PF00333, Ribosomal protein S5, N-terminal domai, score 3.2e-31 216591001302 PS00585 Ribosomal protein S5 signature. 216591001303 HMMPfam hit to PF03719, Ribosomal protein S5, C-terminal domai, score 3.5e-29 216591001304 Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658 216591001305 23S rRNA binding site [nucleotide binding]; other site 216591001306 HMMPfam hit to PF00327, Ribosomal protein L30p/L7e, score 2.1e-13 216591001307 50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592 216591001308 HMMPfam hit to PF01305, Ribosomal protein L15 amino terminal re, score 3.2e-47 216591001309 HMMPfam hit to PF00256, Ribosomal protein L15, score 8.7e-09 216591001310 PS00475 Ribosomal protein L15 signature. 216591001311 preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204 216591001312 SecY translocase; Region: SecY; pfam00344 216591001313 10 probable transmembrane helices predicted for BCAL0254 by TMHMM2.0 at aa 26-45, 76-98, 119-141, 151-173, 180-202, 212-234, 270-292, 319-341, 372-394 and 399-421 216591001314 HMMPfam hit to PF00344, eubacterial secY protein, score 3.2e-173 216591001315 PS00755 Protein secY signature 1. 216591001316 PS00756 Protein secY signature 2. 216591001317 S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451 216591001318 rRNA binding site [nucleotide binding]; other site 216591001319 predicted 30S ribosome binding site; other site 216591001320 HMMPfam hit to PF00575, S1 RNA binding domain, score 2.4e-08 216591001321 HMMPfam hit to PF01176, Translation initiation factor 1A / IF-1, score 2.7e-36 216591001322 Ribosomal protein L36; Region: Ribosomal_L36; pfam00444 216591001323 HMMPfam hit to PF00444, Ribosomal protein L36, score 1.2e-15 216591001324 PS00828 Ribosomal protein L36 signature. 216591001325 30S ribosomal protein S13; Validated; Region: rpsM; PRK05179 216591001326 30S ribosomal protein S13; Region: bact_S13; TIGR03631 216591001327 HMMPfam hit to PF00416, Ribosomal protein S13/S18, score 1.3e-55 216591001328 PS00646 Ribosomal protein S13 signature. 216591001329 30S ribosomal protein S11; Validated; Region: PRK05309 216591001330 HMMPfam hit to PF00411, Ribosomal protein S11, score 1.6e-70 216591001331 PS00054 Ribosomal protein S11 signature. 216591001332 30S ribosomal protein S4; Validated; Region: rpsD; PRK05327 216591001333 Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163 216591001334 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 216591001335 RNA binding surface [nucleotide binding]; other site 216591001336 HMMPfam hit to PF00163, Ribosomal protein S4/S9 N-terminal domai, score 1.9e-31 216591001337 Predicted helix-turn-helix motif with score 1167.000, SD 3.16 at aa 57-78, sequence REKQKVKRIYGVLERQFRRYFA 216591001338 PS00632 Ribosomal protein S4 signature. 216591001339 HMMPfam hit to PF01479, S4 domain, score 3e-20 216591001340 DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182 216591001341 N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928 216591001342 alphaNTD homodimer interface [polypeptide binding]; other site 216591001343 alphaNTD - beta interaction site [polypeptide binding]; other site 216591001344 alphaNTD - beta' interaction site [polypeptide binding]; other site 216591001345 Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118 216591001346 HMMPfam hit to PF01193, RNA polymerase Rpb3/Rpb11 dimerisation, score 2.1e-20 216591001347 HMMPfam hit to PF01000, RNA polymerase Rpb3/RpoA insert domain, score 3.7e-48 216591001348 HMMPfam hit to PF03118, Bacterial RNA polymerase, alpha chain C, score 9.3e-28 216591001349 50S ribosomal protein L17; Validated; Region: rplQ; PRK05591 216591001350 HMMPfam hit to PF01196, Ribosomal protein L17, score 4.8e-53 216591001351 PS01167 Ribosomal protein L17 signature. 216591001352 Uncharacterized protein involved in tolerance to divalent cations [Inorganic ion transport and metabolism]; Region: CutA; COG1324 216591001353 HMMPfam hit to PF03091, CutA1 divalent ion tolerance protein, score 1.1e-19 216591001354 thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293 216591001355 Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412 216591001356 Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788 216591001357 DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953 216591001358 DsbD alpha interface [polypeptide binding]; other site 216591001359 catalytic residues [active] 216591001360 9 probable transmembrane helices predicted for BCAL0263 by TMHMM2.0 at aa 13-35, 189-211, 232-254, 269-288, 322-344, 354-376, 389-411, 415-437 and 444-466 216591001361 HMMPfam hit to PF02683, Cytochrome C biogenesis protein transmemb, score 2.8e-06 216591001362 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001363 HMMPfam hit to PF00085, Thioredoxin, score 0.00091 216591001364 PS00194 Thioredoxin family active site. 216591001365 Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823 216591001366 dimer interface [polypeptide binding]; other site 216591001367 active site 216591001368 aspartate-rich active site metal binding site; other site 216591001369 allosteric magnesium binding site [ion binding]; other site 216591001370 Schiff base residues; other site 216591001371 HMMPfam hit to PF00490, Delta-aminolevulinic acid dehydratase, score 1e-200 216591001372 PS00169 Delta-aminolevulinic acid dehydratase active site. 216591001373 YihA (EngB) GTPase family; Region: YihA_EngB; cd01876 216591001374 G1 box; other site 216591001375 GTP/Mg2+ binding site [chemical binding]; other site 216591001376 Switch I region; other site 216591001377 G2 box; other site 216591001378 G3 box; other site 216591001379 Switch II region; other site 216591001380 G4 box; other site 216591001381 G5 box; other site 216591001382 HMMPfam hit to PF01926, GTPase of unknown function, score 1e-27 216591001383 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001384 Cytochrome c553 [Energy production and conversion]; Region: COG2863 216591001385 Cytochrome c; Region: Cytochrom_C; cl11414 216591001386 HMMPfam hit to PF00034, Cytochrome c, score 3e-09 216591001387 PS00190 Cytochrome c family heme-binding site signature. 216591001388 HMMPfam hit to PF00034, Cytochrome c, score 0.0016 216591001389 PS00190 Cytochrome c family heme-binding site signature. 216591001390 ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125 216591001391 ResB-like family; Region: ResB; pfam05140 216591001392 HMMPfam hit to PF05140, ResB-like family, score 3.3e-123 216591001393 4 probable transmembrane helices predicted for BCAL0267 by TMHMM2.0 at aa 5-22, 50-72, 148-170 and 616-634 216591001394 cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144 216591001395 10 probable transmembrane helices predicted for BCAL0268 by TMHMM2.0 at aa 34-56, 85-102, 122-144, 156-175, 190-209, 216-238, 258-280, 301-323, 338-357 and 364-386 216591001396 HMMPfam hit to PF01578, Cytochrome C assembly protein, score 1.2e-55 216591001397 TMAO/DMSO reductase; Reviewed; Region: PRK05363 216591001398 Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199 216591001399 Moco binding site; other site 216591001400 metal coordination site [ion binding]; other site 216591001401 1 probable transmembrane helix predicted for BCAL0269 by TMHMM2.0 at aa 34-56 216591001402 HMMPfam hit to PF00174, Oxidoreductase molybdopterin binding d, score 8.4e-68 216591001403 putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419 216591001404 6 probable transmembrane helices predicted for BCAL0270 by TMHMM2.0 at aa 33-55, 68-90, 105-124, 137-159, 174-193 and 205-223 216591001405 HMMPfam hit to PF01794, Ferric reductase like transmembrane com, score 5.2e-32 216591001406 Prokaryotic lipoprotein-attachment site; Region: LPAM_2; pfam13627 216591001407 1 probable transmembrane helix predicted for BCAL0272 by TMHMM2.0 at aa 7-29 216591001408 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001409 frataxin-like protein; Provisional; Region: cyaY; PRK00446 216591001410 putative iron binding site [ion binding]; other site 216591001411 HMMPfam hit to PF01491, Frataxin-like domain, score 2.7e-35 216591001412 Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009 216591001413 Transglycosylase; Region: Transgly; pfam00912 216591001414 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 216591001415 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 3.4e-39 216591001416 HMMPfam hit to PF00912, Transglycosylase, score 1.8e-90 216591001417 1 probable transmembrane helix predicted for BCAL0274 by TMHMM2.0 at aa 25-47 216591001418 Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972 216591001419 HMMPfam hit to PF05137, Fimbrial assembly protein (PilN), score 0.034 216591001420 1 probable transmembrane helix predicted for BCAL0276 by TMHMM2.0 at aa 43-65 216591001421 type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515 216591001422 Secretin and TonB N terminus short domain; Region: STN; pfam07660 216591001423 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 216591001424 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 216591001425 1 probable transmembrane helix predicted for BCAL0278 by TMHMM2.0 at aa 7-29 216591001426 HMMPfam hit to PF07660, Secretin and TonB N terminus short domain, score 2.7e-12 216591001427 HMMPfam hit to PF03958, Bacterial type II/III secretion system sho, score 3.4e-07 216591001428 HMMPfam hit to PF00263, Bacterial type II and III secretion system, score 3.6e-64 216591001429 PS00875 Bacterial type II secretion system protein D signature. 216591001430 shikimate kinase; Reviewed; Region: aroK; PRK00131 216591001431 Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464 216591001432 ADP binding site [chemical binding]; other site 216591001433 magnesium binding site [ion binding]; other site 216591001434 putative shikimate binding site; other site 216591001435 PS00267 Tachykinin family signature. 216591001436 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001437 HMMPfam hit to PF01202, Shikimate kinase, score 5.5e-77 216591001438 PS01128 Shikimate kinase signature. 216591001439 Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195 216591001440 active site 216591001441 dimer interface [polypeptide binding]; other site 216591001442 metal binding site [ion binding]; metal-binding site 216591001443 HMMPfam hit to PF01761, 3-dehydroquinate synthase, score 3.6e-175 216591001444 deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286 216591001445 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 216591001446 Zn2+ binding site [ion binding]; other site 216591001447 Mg2+ binding site [ion binding]; other site 216591001448 Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286 216591001449 HMMPfam hit to PF01966, HD domain, score 1.3e-16 216591001450 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 216591001451 glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974 216591001452 1 probable transmembrane helix predicted for BCAL0282 by TMHMM2.0 at aa 7-29 216591001453 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 7.8e-20 216591001454 PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 216591001455 ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209 216591001456 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591001457 dimer interface [polypeptide binding]; other site 216591001458 conserved gate region; other site 216591001459 putative PBP binding loops; other site 216591001460 ABC-ATPase subunit interface; other site 216591001461 6 probable transmembrane helices predicted for BCAL0283 by TMHMM2.0 at aa 12-34, 74-96, 109-129, 144-166, 205-227 and 265-287 216591001462 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6.3e-13 216591001463 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001464 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591001465 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 216591001466 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591001467 dimer interface [polypeptide binding]; other site 216591001468 conserved gate region; other site 216591001469 putative PBP binding loops; other site 216591001470 ABC-ATPase subunit interface; other site 216591001471 8 probable transmembrane helices predicted for BCAL0284 by TMHMM2.0 at aa 10-32, 41-63, 83-105, 112-130, 145-167, 188-210, 215-234 and 247-269 216591001472 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 8.9e-23 216591001473 glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650 216591001474 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 216591001475 Walker A/P-loop; other site 216591001476 ATP binding site [chemical binding]; other site 216591001477 Q-loop/lid; other site 216591001478 ABC transporter signature motif; other site 216591001479 Walker B; other site 216591001480 D-loop; other site 216591001481 H-loop/switch region; other site 216591001482 HMMPfam hit to PF00005, ABC transporter, score 1.1e-57 216591001483 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001484 PS00211 ABC transporters family signature. 216591001485 HMMPfam hit to PF08402, TOBE domain, score 5.6e-08 216591001486 cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454 216591001487 Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562 216591001488 putative active site [active] 216591001489 catalytic site [active] 216591001490 putative metal binding site [ion binding]; other site 216591001491 HMMPfam hit to PF03009, Glycerophosphoryl diester phosphodiesterase, score 1.6e-57 216591001492 Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047 216591001493 HMMPfam hit to PF03922, OmpW family, score 2.8e-14 216591001494 1 probable transmembrane helix predicted for BCAL0287 by TMHMM2.0 at aa 5-27 216591001495 Transposase IS200 like; Region: Y1_Tnp; cl00848 216591001496 HMMPfam hit to PF07605, Protein of unknown function (DUF1568), score 1.1e-08 216591001497 glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750 216591001498 Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713 216591001499 active site 216591001500 dimer interface [polypeptide binding]; other site 216591001501 Glutamate synthase central domain; Region: Glu_syn_central; pfam04898 216591001502 Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808 216591001503 active site 216591001504 FMN binding site [chemical binding]; other site 216591001505 substrate binding site [chemical binding]; other site 216591001506 3Fe-4S cluster binding site [ion binding]; other site 216591001507 gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982 216591001508 domain interface; other site 216591001509 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 4.7e-224 216591001510 HMMPfam hit to PF04898, Glutamate synthase central domain, score 6.7e-175 216591001511 HMMPfam hit to PF01645, Conserved region in glutamate synthas, score 1.6e-232 216591001512 HMMPfam hit to PF01493, GXGXG motif, score 1.8e-91 216591001513 glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810 216591001514 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591001515 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591001516 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 6.9e-25 216591001517 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 0.002 216591001518 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 216591001519 amino acid carrier protein; Region: agcS; TIGR00835 216591001520 9 probable transmembrane helices predicted for BCAL0291 by TMHMM2.0 at aa 15-34, 77-99, 141-163, 184-203, 218-240, 300-322, 349-371, 384-406 and 416-435 216591001521 HMMPfam hit to PF01235, Sodium:alanine symporter family, score 6.4e-197 216591001522 PS00873 Sodium:alanine symporter family signature. 216591001523 2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258 216591001524 LigT like Phosphoesterase; Region: LigT_PEase; pfam02834 216591001525 HMMPfam hit to PF02834, 2',5' RNA ligase family, score 1.1e-05 216591001526 HMMPfam hit to PF02834, 2',5' RNA ligase family, score 0.0057 216591001527 D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711 216591001528 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591001529 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 6.5e-88 216591001530 benzoate transport; Region: 2A0115; TIGR00895 216591001531 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591001532 putative substrate translocation pore; other site 216591001533 HMMPfam hit to PF00083, Sugar (and other) transporter, score 1.4e-07 216591001534 10 probable transmembrane helices predicted for BCAL0294 by TMHMM2.0 at aa 21-43, 53-75, 149-168, 172-191, 228-250, 265-287, 294-316, 321-343, 356-378 and 382-404 216591001535 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.4e-43 216591001536 PS00216 Sugar transport proteins signature 1. 216591001537 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591001538 NAD(P) binding site [chemical binding]; other site 216591001539 active site 216591001540 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0012 216591001541 HMMPfam hit to PF00106, short chain dehydrogenase, score 4.4e-08 216591001542 1 probable transmembrane helix predicted for BCAL0295 by TMHMM2.0 at aa 7-26 216591001543 ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178 216591001544 ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549 216591001545 ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223 216591001546 HMMPfam hit to PF00005, ABC transporter, score 3.2e-26 216591001547 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001548 HMMPfam hit to PF06472, ABC transporter transmembrane region, score 1.9e-71 216591001549 5 probable transmembrane helices predicted for BCAL0296 by TMHMM2.0 at aa 36-58, 81-103, 163-182, 192-214 and 285-307 216591001550 tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137 216591001551 glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352 216591001552 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.2e-42 216591001553 sulfur carrier protein ThiS; Provisional; Region: PRK06944 216591001554 charged pocket; other site 216591001555 hydrophobic patch; other site 216591001556 HMMPfam hit to PF02597, ThiS family, score 3.4e-13 216591001557 Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728 216591001558 ThiS interaction site; other site 216591001559 putative active site [active] 216591001560 tetramer interface [polypeptide binding]; other site 216591001561 HMMPfam hit to PF05690, Thiazole biosynthesis protein ThiG, score 2.2e-159 216591001562 PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 216591001563 Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564 216591001564 thiamine phosphate binding site [chemical binding]; other site 216591001565 active site 216591001566 pyrophosphate binding site [ion binding]; other site 216591001567 HMMPfam hit to PF02581, Thiamine monophosphate synthase/TENI, score 1.2e-65 216591001568 ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127 216591001569 ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261 216591001570 Walker A/P-loop; other site 216591001571 ATP binding site [chemical binding]; other site 216591001572 Q-loop/lid; other site 216591001573 ABC transporter signature motif; other site 216591001574 Walker B; other site 216591001575 D-loop; other site 216591001576 H-loop/switch region; other site 216591001577 HMMPfam hit to PF00005, ABC transporter, score 4.7e-52 216591001578 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001579 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001580 PS00211 ABC transporters family signature. 216591001581 ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767 216591001582 Permease; Region: Permease; pfam02405 216591001583 HMMPfam hit to PF02405, Domain of unknown function DUF140, score 3.4e-95 216591001584 5 probable transmembrane helices predicted for BCAL0302 by TMHMM2.0 at aa 46-68, 83-105, 153-175, 195-214 and 235-254 216591001585 ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463 216591001586 mce related protein; Region: MCE; pfam02470 216591001587 1 probable transmembrane helix predicted for BCAL0303 by TMHMM2.0 at aa 7-28 216591001588 HMMPfam hit to PF02470, mce related protein, score 2.2e-27 216591001589 VacJ like lipoprotein; Region: VacJ; cl01073 216591001590 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001591 HMMPfam hit to PF04333, VacJ like lipoprotein, score 3.2e-91 216591001592 Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; pfam05494 216591001593 HMMPfam hit to PF05494, Toluene tolerance, Ttg2, score 2.9e-49 216591001594 Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043 216591001595 anti sigma factor interaction site; other site 216591001596 regulatory phosphorylation site [posttranslational modification]; other site 216591001597 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 216591001598 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 216591001599 Walker A/P-loop; other site 216591001600 ATP binding site [chemical binding]; other site 216591001601 Q-loop/lid; other site 216591001602 ABC transporter signature motif; other site 216591001603 Walker B; other site 216591001604 D-loop; other site 216591001605 H-loop/switch region; other site 216591001606 HMMPfam hit to PF00005, ABC transporter, score 5e-59 216591001607 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001608 PS00211 ABC transporters family signature. 216591001609 ABC-2 type transporter; Region: ABC2_membrane; cl17235 216591001610 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 216591001611 HMMPfam hit to PF01061, ABC-2 type transporter, score 5.7e-42 216591001612 6 probable transmembrane helices predicted for BCAL0308 by TMHMM2.0 at aa 20-42, 52-74, 107-129, 139-161, 173-195 and 224-246 216591001613 PS00890 ABC-2 type transport system integral membrane proteins signature. 216591001614 Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007 216591001615 HMMPfam hit to PF01722, BolA-like protein, score 1.2e-21 216591001616 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072 216591001617 UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555 216591001618 hinge; other site 216591001619 active site 216591001620 HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 1.8e-144 216591001621 ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686 216591001622 ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040 216591001623 HMMPfam hit to PF01634, ATP phosphoribosyltransferase, score 4.1e-53 216591001624 PS01316 ATP phosphoribosyltransferase signature. 216591001625 Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141 216591001626 Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572 216591001627 NAD binding site [chemical binding]; other site 216591001628 dimerization interface [polypeptide binding]; other site 216591001629 product binding site; other site 216591001630 substrate binding site [chemical binding]; other site 216591001631 zinc binding site [ion binding]; other site 216591001632 catalytic residues [active] 216591001633 HMMPfam hit to PF00815, Histidinol dehydrogenase, score 1.7e-187 216591001634 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591001635 histidinol-phosphate aminotransferase; Provisional; Region: PRK04870 216591001636 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591001637 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591001638 homodimer interface [polypeptide binding]; other site 216591001639 catalytic residue [active] 216591001640 HMMPfam hit to PF00155, Aminotransferase class I and II, score 9.7e-45 216591001641 Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914 216591001642 putative active site pocket [active] 216591001643 4-fold oligomerization interface [polypeptide binding]; other site 216591001644 metal binding residues [ion binding]; metal-binding site 216591001645 3-fold/trimer interface [polypeptide binding]; other site 216591001646 HMMPfam hit to PF00475, Imidazoleglycerol-phosphate dehydratase, score 4e-91 216591001647 PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 216591001648 PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 216591001649 MarC family integral membrane protein; Region: MarC; cl00919 216591001650 HMMPfam hit to PF01914, MarC family integral membrane protein, score 2.1e-71 216591001651 6 probable transmembrane helices predicted for BCAL0315 by TMHMM2.0 at aa 4-26, 39-61, 65-87, 111-133, 143-160 and 181-203 216591001652 imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13146 216591001653 Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748 216591001654 putative active site [active] 216591001655 oxyanion strand; other site 216591001656 catalytic triad [active] 216591001657 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 4.5e-31 216591001658 PS00442 Glutamine amidotransferases class-I active site. 216591001659 HisA. Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732 216591001660 Histidine biosynthesis protein; Region: His_biosynth; pfam00977 216591001661 catalytic residues [active] 216591001662 HMMPfam hit to PF00977, Histidine biosynthesis protein, score 4e-121 216591001663 The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731 216591001664 Histidine biosynthesis protein; Region: His_biosynth; pfam00977 216591001665 substrate binding site [chemical binding]; other site 216591001666 glutamase interaction surface [polypeptide binding]; other site 216591001667 HMMPfam hit to PF00977, Histidine biosynthesis protein, score 5.4e-138 216591001668 phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051 216591001669 HMMPfam hit to PF01502, Phosphoribosyl-AMP cyclohydrolase, score 9.8e-53 216591001670 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534 216591001671 metal binding site [ion binding]; metal-binding site 216591001672 HMMPfam hit to PF01503, Phosphoribosyl-ATP pyrophosphohydrolase, score 6.2e-36 216591001673 Predicted membrane protein [Function unknown]; Region: COG3671 216591001674 2 probable transmembrane helices predicted for BCAL0321 by TMHMM2.0 at aa 39-61 and 88-110 216591001675 Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276 216591001676 nucleotide binding site/active site [active] 216591001677 HIT family signature motif; other site 216591001678 catalytic residue [active] 216591001679 HMMPfam hit to PF01230, HIT domain, score 1.1e-40 216591001680 twin arginine translocase protein A; Provisional; Region: tatA; PRK02958 216591001681 HMMPfam hit to PF02416, mttA/Hcf106 family, score 6.4e-08 216591001682 1 probable transmembrane helix predicted for BCAL0323 by TMHMM2.0 at aa 4-21 216591001683 sec-independent translocase; Provisional; Region: tatB; PRK01919 216591001684 HMMPfam hit to PF02416, mttA/Hcf106 family, score 0.0002 216591001685 Sec-independent protein translocase protein (TatC); Region: TatC; cl00521 216591001686 HMMPfam hit to PF00902, Sec-independent protein translocase protein, score 1.1e-92 216591001687 6 probable transmembrane helices predicted for BCAL0325 by TMHMM2.0 at aa 27-49, 81-103, 123-145, 165-187, 200-218 and 223-245 216591001688 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265 216591001689 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 216591001690 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 216591001691 protein binding site [polypeptide binding]; other site 216591001692 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 1.1e-13 216591001693 HMMPfam hit to PF00089, Trypsin, score 4.5e-18 216591001694 1 probable transmembrane helix predicted for BCAL0326 by TMHMM2.0 at aa 5-24 216591001695 Uncharacterized conserved protein [Function unknown]; Region: COG0327 216591001696 NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371 216591001697 HMMPfam hit to PF01784, NIF3 (NGG1p interacting factor 3), score 1.1e-93 216591001698 Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470 216591001699 ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416 216591001700 [2Fe-2S] cluster binding site [ion binding]; other site 216591001701 1 probable transmembrane helix predicted for BCAL0328 by TMHMM2.0 at aa 17-39 216591001702 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 2e-05 216591001703 PS00199 Rieske iron-sulfur protein signature 1. 216591001704 PS00200 Rieske iron-sulfur protein signature 2. 216591001705 Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290 216591001706 Cytochrome b (N-terminus)/b6/petB: Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284 216591001707 Qi binding site; other site 216591001708 intrachain domain interface; other site 216591001709 interchain domain interface [polypeptide binding]; other site 216591001710 heme bH binding site [chemical binding]; other site 216591001711 heme bL binding site [chemical binding]; other site 216591001712 Qo binding site; other site 216591001713 interchain domain interface [polypeptide binding]; other site 216591001714 intrachain domain interface; other site 216591001715 Qi binding site; other site 216591001716 Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032 216591001717 Qo binding site; other site 216591001718 HMMPfam hit to PF00033, Cytochrome b(N-terminal)/b6/petB, score 1.9e-86 216591001719 11 probable transmembrane helices predicted for BCAL0329 by TMHMM2.0 at aa 42-64, 89-111, 126-148, 160-179, 194-216, 254-276, 311-333, 340-357, 361-380, 392-414 and 424-446 216591001720 PS00192 Cytochrome b/b6 heme-ligand signature. 216591001721 Cytochrome C1 family; Region: Cytochrom_C1; pfam02167 216591001722 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001723 HMMPfam hit to PF02167, Cytochrome C1 family, score 4.6e-07 216591001724 PS00190 Cytochrome c family heme-binding site signature. 216591001725 1 probable transmembrane helix predicted for BCAL0330 by TMHMM2.0 at aa 224-246 216591001726 stringent starvation protein A; Provisional; Region: sspA; PRK09481 216591001727 GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059 216591001728 C-terminal domain interface [polypeptide binding]; other site 216591001729 putative GSH binding site (G-site) [chemical binding]; other site 216591001730 dimer interface [polypeptide binding]; other site 216591001731 C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186 216591001732 dimer interface [polypeptide binding]; other site 216591001733 N-terminal domain interface [polypeptide binding]; other site 216591001734 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal do, score 2.9e-17 216591001735 HMMPfam hit to PF00462, Glutaredoxin, score 0.004 216591001736 ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798 216591001737 HMMPfam hit to PF04386, Stringent starvation protein B, score 4.9e-52 216591001738 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591001739 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591001740 substrate binding pocket [chemical binding]; other site 216591001741 membrane-bound complex binding site; other site 216591001742 hinge residues; other site 216591001743 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 9.3e-93 216591001744 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591001745 1 probable transmembrane helix predicted for BCAL0334 by TMHMM2.0 at aa 7-26 216591001746 Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850 216591001747 1 probable transmembrane helix predicted for BCAL0337 by TMHMM2.0 at aa 209-231 216591001748 type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353 216591001749 Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936 216591001750 HMMPfam hit to PF05936, Bacterial protein of unknown function (DUF87, score 9.6e-179 216591001751 Type VI secretion lipoprotein; Region: T6SS-SciN; cl01405 216591001752 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001753 1 probable transmembrane helix predicted for BCAL0339 by TMHMM2.0 at aa 5-27 216591001754 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001755 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591001756 TPR motif; other site 216591001757 binding surface 216591001758 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001759 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0047 216591001760 Protein of unknown function (DUF770); Region: DUF770; pfam05591 216591001761 HMMPfam hit to PF05591, Protein of unknown function (DUF770), score 2e-88 216591001762 type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355 216591001763 Protein of unknown function (DUF877); Region: DUF877; pfam05943 216591001764 HMMPfam hit to PF05943, Protein of unknown function (DUF877), score 0 216591001765 Protein of unknown function (DUF796); Region: DUF796; pfam05638 216591001766 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 8.2e-50 216591001767 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3518 216591001768 HMMPfam hit to PF07025, Protein of unknown function (DUF1316), score 3e-53 216591001769 Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3519 216591001770 type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359 216591001771 HMMPfam hit to PF05947, Bacterial protein of unknown function (DUF87, score 1.4e-240 216591001772 Protein of unknown function (DUF1305); Region: DUF1305; pfam06996 216591001773 HMMPfam hit to PF06996, Protein of unknown function (DUF1305), score 1.7e-93 216591001774 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591001775 type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345 216591001776 Clp amino terminal domain; Region: Clp_N; pfam02861 216591001777 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591001778 Walker A motif; other site 216591001779 ATP binding site [chemical binding]; other site 216591001780 Walker B motif; other site 216591001781 arginine finger; other site 216591001782 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591001783 Walker A motif; other site 216591001784 ATP binding site [chemical binding]; other site 216591001785 Walker B motif; other site 216591001786 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; cl11083 216591001787 HMMPfam hit to PF02861, Clp amino terminal domain, score 1.2e-08 216591001788 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.1e-06 216591001789 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001790 PS00870 Chaperonins clpA/B signature 1. 216591001791 HMMPfam hit to PF07724, ATPase family associated with various cellul, score 5.9e-89 216591001792 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 3.2e-05 216591001793 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001794 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001795 type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363 216591001796 ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812 216591001797 HMMPfam hit to PF06812, ImpA-related N-terminal, score 1.2e-24 216591001798 Merozoite surface protein 1 (MSP1) C-terminus; Region: MSP1_C; pfam07462 216591001799 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 216591001800 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591001801 ligand binding site [chemical binding]; other site 216591001802 HMMPfam hit to PF00691, OmpA family, score 1.8e-35 216591001803 1 probable transmembrane helix predicted for BCAL0349 by TMHMM2.0 at aa 12-34 216591001804 Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; cl01611 216591001805 ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331 216591001806 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 216591001807 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 216591001808 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 216591001809 HMMPfam hit to PF06744, Protein of unknown function (DUF1215), score 1.6e-35 216591001810 HMMPfam hit to PF06761, ImcF-related, score 6.8e-76 216591001811 3 probable transmembrane helices predicted for BCAL0351 by TMHMM2.0 at aa 13-30, 35-57 and 444-466 216591001812 PS00242 Integrins alpha chain signature. 216591001813 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001814 D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557 216591001815 D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539 216591001816 HMMPfam hit to PF02557, D-alanyl-D-alanine carboxypeptidase, score 0.00022 216591001817 2 probable transmembrane helices predicted for BCAL0352 by TMHMM2.0 at aa 7-29 and 78-97 216591001818 CorA-like Mg2+ transporter protein; Region: CorA; pfam01544 216591001819 Uncharacterized bacterial subgroup of the Salmonella typhimurium Zn2+ transporter ZntB-like subfamily; Region: ZntB_u1; cd12834 216591001820 Cl binding site [ion binding]; other site 216591001821 oligomer interface [polypeptide binding]; other site 216591001822 HMMPfam hit to PF01544, CorA-like Mg2+ transporter protein, score 0.00037 216591001823 2 probable transmembrane helices predicted for BCAL0354 by TMHMM2.0 at aa 280-302 and 317-336 216591001824 putative membrane protein (fragment);Probable gene remnant. Similar to the N-terminal regions of several proteins, for example, Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) hypothetical protein UniProt:Q46RN6 (EMBL:CP000091) (97 aa) fasta scores: E()=5.9e-07, 56.000% id in 50 aa, and Pseudomonas aeruginosa hypothetical protein UniProt:Q9I0E5 (EMBL:AE004698) (93 aa) fasta scores: E()=4.4e-06, 65.217% id in 46 aa 216591001825 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 216591001826 NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604 216591001827 NAD(P) binding site [chemical binding]; other site 216591001828 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.5e-14 216591001829 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 2.1e-08 216591001830 transcriptional activator TtdR; Provisional; Region: PRK09801 216591001831 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591001832 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591001833 putative effector binding pocket; other site 216591001834 dimerization interface [polypeptide binding]; other site 216591001835 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.1e-19 216591001836 Predicted helix-turn-helix motif with score 1234.000, SD 3.39 at aa 31-52, sequence QSFSAAARRLGVAASSVTRRID 216591001837 PS00044 Bacterial regulatory proteins, lysR family signature. 216591001838 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.3e-43 216591001839 Peptidase family M1; Region: Peptidase_M1; pfam01433 216591001840 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 216591001841 Zn binding site [ion binding]; other site 216591001842 HMMPfam hit to PF01433, Peptidase family M1, score 5.7e-59 216591001843 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591001844 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001845 Water Stress and Hypersensitive response; Region: WHy; smart00769 216591001846 1 probable transmembrane helix predicted for BCAL0359 by TMHMM2.0 at aa 27-49 216591001847 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001848 Domain of unknown function (DUF1508); Region: DUF1508; pfam07411 216591001849 Domain of unknown function (DUF1508); Region: DUF1508; pfam07411 216591001850 HMMPfam hit to PF07411, Domain of unknown function (DUF1508), score 3.5e-20 216591001851 HMMPfam hit to PF07411, Domain of unknown function (DUF1508), score 5.5e-24 216591001852 Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]; Region: HemK; COG2890 216591001853 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591001854 S-adenosylmethionine binding site [chemical binding]; other site 216591001855 PS00296 Chaperonins cpn60 signature. 216591001856 HMMPfam hit to PF05175, Methyltransferase small domain, score 4.5e-09 216591001857 PS00092 N-6 Adenine-specific DNA methylases signature. 216591001858 Methyltransferase domain; Region: Methyltransf_32; pfam13679 216591001859 Protein of unknown function (DUF1415); Region: DUF1415; pfam07209 216591001860 HMMPfam hit to PF07209, Protein of unknown function (DUF1415), score 4.2e-95 216591001861 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591001862 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591001863 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.2e-16 216591001864 Predicted helix-turn-helix motif with score 1033.000, SD 2.71 at aa 43-64, sequence VGVEAVVERAGVNKMSLYRQFS 216591001865 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591001866 putative substrate translocation pore; other site 216591001867 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591001868 12 probable transmembrane helices predicted for BCAL0365 by TMHMM2.0 at aa 13-32, 52-74, 79-98, 108-130, 142-164, 174-193, 241-263, 278-297, 304-326, 331-353, 365-387 and 391-413 216591001869 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.2e-46 216591001870 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001871 PS00283 Soybean trypsin inhibitor (Kunitz) protease inhibitors family signature. 216591001872 Nitroreductase-like family 2. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_2; cd02138 216591001873 putative FMN binding site [chemical binding]; other site 216591001874 HMMPfam hit to PF00881, Nitroreductase family, score 2.4e-22 216591001875 putative chaperone; Provisional; Region: PRK11678 216591001876 Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231 216591001877 nucleotide binding site [chemical binding]; other site 216591001878 putative NEF/HSP70 interaction site [polypeptide binding]; other site 216591001879 SBD interface [polypeptide binding]; other site 216591001880 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591001881 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 216591001882 DNA-binding site [nucleotide binding]; DNA binding site 216591001883 RNA-binding motif; other site 216591001884 HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 2.9e-40 216591001885 PS00352 'Cold-shock' DNA-binding domain signature. 216591001886 amino acid transporter; Region: 2A0306; TIGR00909 216591001887 14 probable transmembrane helices predicted for BCAL0369 by TMHMM2.0 at aa 9-31, 46-68, 81-103, 129-151, 158-180, 195-217, 238-260, 280-302, 345-362, 366-388, 400-422, 426-444, 457-476 and 486-508 216591001888 HMMPfam hit to PF00324, Amino acid permease, score 1.3e-15 216591001889 The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363 216591001890 Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900 216591001891 putative active site [active] 216591001892 metal binding site [ion binding]; metal-binding site 216591001893 HMMPfam hit to PF02900, Catalytic LigB subunit of aromatic ring-open, score 6.7e-86 216591001894 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029 216591001895 Flavoprotein; Region: Flavoprotein; pfam02441 216591001896 HMMPfam hit to PF02441, Flavoprotein, score 1.4e-49 216591001897 Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028 216591001898 putative GSH binding site [chemical binding]; other site 216591001899 catalytic residues [active] 216591001900 HMMPfam hit to PF00462, Glutaredoxin, score 3.1e-31 216591001901 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328 216591001902 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591001903 S-adenosylmethionine binding site [chemical binding]; other site 216591001904 HMMPfam hit to PF05175, Methyltransferase small domain, score 5.3e-10 216591001905 HMMPfam hit to PF08242, Methyltransferase domain, score 0.00082 216591001906 PS00092 N-6 Adenine-specific DNA methylases signature. 216591001907 peptide chain release factor 1; Validated; Region: prfA; PRK00591 216591001908 This domain is found in peptide chain release factors; Region: PCRF; smart00937 216591001909 RF-1 domain; Region: RF-1; pfam00472 216591001910 HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 1.3e-72 216591001911 HMMPfam hit to PF03462, PCRF domain, score 4e-62 216591001912 glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045 216591001913 NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213 216591001914 tRNA; other site 216591001915 putative tRNA binding site [nucleotide binding]; other site 216591001916 putative NADP binding site [chemical binding]; other site 216591001917 Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745 216591001918 HMMPfam hit to PF00745, Glutamyl-tRNAGlu reductase, dimerisation, score 2.9e-25 216591001919 HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase, score 3.4e-65 216591001920 HMMPfam hit to PF05201, Glutamyl-tRNAGlu reductase, N-terminal d, score 1.9e-66 216591001921 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591001922 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591001923 active site 216591001924 phosphorylation site [posttranslational modification] 216591001925 intermolecular recognition site; other site 216591001926 dimerization interface [polypeptide binding]; other site 216591001927 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591001928 DNA binding site [nucleotide binding] 216591001929 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 4.9e-12 216591001930 HMMPfam hit to PF00072, Response regulator receiver domain, score 0.0012 216591001931 3 probable transmembrane helices predicted for BCAL0376a by TMHMM2.0 at aa 4-21, 28-50 and 60-82 216591001932 Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321 216591001933 Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006 216591001934 X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085 216591001935 active site 216591001936 HMMPfam hit to PF00557, metallopeptidase family M24, score 8.1e-11 216591001937 Isochorismatase family; Region: Isochorismatase; pfam00857 216591001938 Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014 216591001939 catalytic triad [active] 216591001940 conserved cis-peptide bond; other site 216591001941 HMMPfam hit to PF00857, Isochorismatase family, score 2.4e-11 216591001942 Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419 216591001943 ?-D-glucose-1-phosphatase; Provisional; Region: PRK09456 216591001944 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.00075 216591001945 putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819 216591001946 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591001947 Walker A/P-loop; other site 216591001948 ATP binding site [chemical binding]; other site 216591001949 Q-loop/lid; other site 216591001950 ABC transporter signature motif; other site 216591001951 Walker B; other site 216591001952 D-loop; other site 216591001953 H-loop/switch region; other site 216591001954 ABC transporter; Region: ABC_tran_2; pfam12848 216591001955 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 216591001956 HMMPfam hit to PF00005, ABC transporter, score 1.3e-47 216591001957 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001958 HMMPfam hit to PF00005, ABC transporter, score 2.1e-55 216591001959 PS00211 ABC transporters family signature. 216591001960 PS00017 ATP/GTP-binding site motif A (P-loop). 216591001961 Protein of unknown function (DUF3761); Region: DUF3761; pfam12587 216591001962 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001963 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591001964 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591001965 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591001966 dimerization interface [polypeptide binding]; other site 216591001967 substrate binding pocket [chemical binding]; other site 216591001968 HMMPfam hit to PF03466, LysR substrate binding domain, score 7.3e-43 216591001969 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.4e-19 216591001970 PS00044 Bacterial regulatory proteins, lysR family signature. 216591001971 Predicted helix-turn-helix motif with score 1614.000, SD 4.68 at aa 22-43, sequence LSVKSAAEELSVTPGAVSQMIR 216591001972 oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890 216591001973 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591001974 putative substrate translocation pore; other site 216591001975 12 probable transmembrane helices predicted for BCAL0383 by TMHMM2.0 at aa 17-39, 59-81, 88-110, 114-136, 149-171, 175-197, 245-267, 277-299, 311-329, 334-356, 368-390 and 394-416 216591001976 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.8e-56 216591001977 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591001978 PS00216 Sugar transport proteins signature 1. 216591001979 Protein of unknown function (DUF419); Region: DUF419; cl15265 216591001980 HMMPfam hit to PF04944, Uncharacterised BCR (COG3801), score 2.3e-34 216591001981 gamma-aminobutyrate permease; Region: GABAperm; TIGR01773 216591001982 HMMPfam hit to PF00324, Amino acid permease, score 4.6e-146 216591001983 12 probable transmembrane helices predicted for BCAL0385 by TMHMM2.0 at aa 17-39, 44-63, 84-106, 121-143, 155-177, 192-214, 238-260, 285-307, 334-353, 357-379, 399-421 and 426-445 216591001984 PS00218 Amino acid permeases signature. 216591001985 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 216591001986 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 5.6e-17 216591001987 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591001988 GTP-binding protein YchF; Reviewed; Region: PRK09601 216591001989 YchF GTPase; Region: YchF; cd01900 216591001990 G1 box; other site 216591001991 GTP/Mg2+ binding site [chemical binding]; other site 216591001992 Switch I region; other site 216591001993 G2 box; other site 216591001994 Switch II region; other site 216591001995 G3 box; other site 216591001996 G4 box; other site 216591001997 G5 box; other site 216591001998 TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867 216591001999 HMMPfam hit to PF06071, Protein of unknown function (DUF933), score 2.7e-59 216591002000 HMMPfam hit to PF01926, GTPase of unknown function, score 1.6e-31 216591002001 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002002 PS00443 Glutamine amidotransferases class-II active site. 216591002003 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608 216591002004 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988 216591002005 HMMPfam hit to PF01494, FAD binding domain, score 3e-10 216591002006 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002007 PS01304 ubiH/COQ6 monooxygenase family signature. 216591002008 Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651 216591002009 DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020 216591002010 dimerization domain [polypeptide binding]; other site 216591002011 dimer interface [polypeptide binding]; other site 216591002012 catalytic residues [active] 216591002013 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002014 PS00194 Thioredoxin family active site. 216591002015 Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975 216591002016 M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299 216591002017 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 216591002018 protein binding site [polypeptide binding]; other site 216591002019 HMMPfam hit to PF05299, M61 glycyl aminopeptidase, score 6.5e-71 216591002020 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591002021 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 0.018 216591002022 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 216591002023 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591002024 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 0.00038 216591002025 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591002026 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591002027 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591002028 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591002029 Predicted helix-turn-helix motif with score 1703.000, SD 4.99 at aa 20-41, sequence EAIRAVARTHGLSHSTVSQWYA 216591002030 putative transposase OrfB; Reviewed; Region: PHA02517 216591002031 HTH-like domain; Region: HTH_21; pfam13276 216591002032 Integrase core domain; Region: rve; pfam00665 216591002033 Integrase core domain; Region: rve_2; pfam13333 216591002034 HMMPfam hit to PF00665, Integrase core domain, score 5.1e-42 216591002035 Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027 216591002036 ligand binding site [chemical binding]; other site 216591002037 active site 216591002038 UGI interface [polypeptide binding]; other site 216591002039 catalytic site [active] 216591002040 HMMPfam hit to PF03167, Uracil DNA glycosylase superfamily, score 2.1e-71 216591002041 PS00130 Uracil-DNA glycosylase signature. 216591002042 Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756 216591002043 putative active site [active] 216591002044 putative metal binding residues [ion binding]; other site 216591002045 signature motif; other site 216591002046 putative triphosphate binding site [ion binding]; other site 216591002047 HMMPfam hit to PF01928, CYTH domain, score 2.2e-40 216591002048 Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331 216591002049 active site 216591002050 ribulose/triose binding site [chemical binding]; other site 216591002051 phosphate binding site [ion binding]; other site 216591002052 substrate (anthranilate) binding pocket [chemical binding]; other site 216591002053 product (indole) binding pocket [chemical binding]; other site 216591002054 HMMPfam hit to PF00218, Indole-3-glycerol phosphate synthase, score 8.4e-129 216591002055 PS00614 Indole-3-glycerol phosphate synthase signature. 216591002056 anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188 216591002057 Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885 216591002058 Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591 216591002059 HMMPfam hit to PF00591, Glycosyl transferase family, a/b doma, score 9.1e-126 216591002060 HMMPfam hit to PF02885, Glycosyl transferase family, helical, score 2.6e-09 216591002061 para-aminobenzoate synthase component II; Provisional; Region: PRK08857 216591002062 Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743 216591002063 glutamine binding [chemical binding]; other site 216591002064 catalytic triad [active] 216591002065 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 5.5e-89 216591002066 PS00442 Glutamine amidotransferases class-I active site. 216591002067 anthranilate synthase component I; Provisional; Region: PRK13565 216591002068 Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715 216591002069 chorismate binding enzyme; Region: Chorismate_bind; pfam00425 216591002070 HMMPfam hit to PF00425, chorismate binding enzyme, score 4e-154 216591002071 HMMPfam hit to PF04715, Anthranilate synthase component I, N, score 1.6e-53 216591002072 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915 216591002073 phosphoglycolate phosphatase; Provisional; Region: PRK13222 216591002074 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591002075 motif II; other site 216591002076 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 7.3e-38 216591002077 Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429 216591002078 ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163 216591002079 substrate binding site [chemical binding]; other site 216591002080 hexamer interface [polypeptide binding]; other site 216591002081 metal binding site [ion binding]; metal-binding site 216591002082 HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase /, score 0.0029 216591002083 HMMPfam hit to PF00834, Ribulose-phosphate 3 epimerase family, score 4.3e-140 216591002084 PS01086 Ribulose-phosphate 3-epimerase family signature 2. 216591002085 PS01085 Ribulose-phosphate 3-epimerase family signature 1. 216591002086 CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461 216591002087 HMMPfam hit to PF04379, Protein of unknown function (DUF525), score 2.3e-50 216591002088 MltA specific insert domain; Region: MltA; smart00925 216591002089 3D domain; Region: 3D; pfam06725 216591002090 1 probable transmembrane helix predicted for BCAL0403 by TMHMM2.0 at aa 12-34 216591002091 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002092 HMMPfam hit to PF03562, MltA N-terminal domain, score 3.9e-83 216591002093 HMMPfam hit to PF06725, 3D domain, score 4.1e-33 216591002094 Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913 216591002095 phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155 216591002096 active site 216591002097 AMP binding site [chemical binding]; other site 216591002098 homodimer interface [polypeptide binding]; other site 216591002099 acyl-activating enzyme (AAE) consensus motif; other site 216591002100 CoA binding site [chemical binding]; other site 216591002101 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 216591002102 CoenzymeA binding site [chemical binding]; other site 216591002103 subunit interaction site [polypeptide binding]; other site 216591002104 PHB binding site; other site 216591002105 HMMPfam hit to PF03061, Thioesterase superfamily, score 9.9e-17 216591002106 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002107 enoyl-CoA hydratase; Provisional; Region: PRK08140 216591002108 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591002109 substrate binding site [chemical binding]; other site 216591002110 oxyanion hole (OAH) forming residues; other site 216591002111 trimer interface [polypeptide binding]; other site 216591002112 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 9.6e-58 216591002113 PS00166 Enoyl-CoA hydratase/isomerase signature. 216591002114 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002115 beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050 216591002116 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 216591002117 dimer interface [polypeptide binding]; other site 216591002118 active site 216591002119 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 1.7e-62 216591002120 PS00099 Thiolases active site. 216591002121 PS00737 Thiolases signature 2. 216591002122 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 8.2e-101 216591002123 PS00098 Thiolases acyl-enzyme intermediate signature. 216591002124 phenylacetic acid degradation protein paaN; Region: PaaN_2; TIGR02288 216591002125 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 216591002126 NAD(P) binding site [chemical binding]; other site 216591002127 catalytic residues [active] 216591002128 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 2e-10 216591002129 enoyl-CoA hydratase; Provisional; Region: PRK05862 216591002130 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591002131 substrate binding site [chemical binding]; other site 216591002132 oxyanion hole (OAH) forming residues; other site 216591002133 trimer interface [polypeptide binding]; other site 216591002134 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 5.6e-74 216591002135 PS00166 Enoyl-CoA hydratase/isomerase signature. 216591002136 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002137 BcenGI3 216591002138 Transposase; Region: HTH_Tnp_1; pfam01527 216591002139 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591002140 CDS lacks appropriate translational start site. It is likely that this CDS encodes the C-terminal region of a larger protein encompassing the upstream CDS. A translational frameshift possibly occurs after residue 86 of the upstream overlapping CDS 216591002141 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591002142 Probable gene remnant. Similar to the C-terminal region of Verminephrobacter eiseniae hypothetical protein UniProt:Q0XH92 (EMBL:CP000542 (296 aa) fasta scores: E()=1.7e-51, 76.136% id in 176 aa 216591002143 CDS lacks appropriate translational start site. It is likely that this CDS encodes the C-terminal region of a larger protein encompassing the upstream CDS. A translational frameshift possibly occurs after residue 86 of the upstream overlapping CDS 216591002144 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591002145 Transposase; Region: HTH_Tnp_1; pfam01527 216591002146 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591002147 Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732 216591002148 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 216591002149 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 216591002150 HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 1.7e-13 216591002151 HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 4.7e-12 216591002152 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610 216591002153 Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313 216591002154 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 216591002155 ATP binding site [chemical binding]; other site 216591002156 putative Mg++ binding site [ion binding]; other site 216591002157 Domain of unknown function (DUF3387); Region: DUF3387; pfam11867 216591002158 HMMPfam hit to PF04313, Type I restriction enzyme R protein N term, score 2.8e-40 216591002159 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 4.1e-07 216591002160 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.024 216591002161 DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939 216591002162 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591002163 ATP binding site [chemical binding]; other site 216591002164 Mg2+ binding site [ion binding]; other site 216591002165 G-X-G motif; other site 216591002166 TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822 216591002167 anchoring element; other site 216591002168 dimer interface [polypeptide binding]; other site 216591002169 ATP binding site [chemical binding]; other site 216591002170 TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366 216591002171 active site 216591002172 putative metal-binding site [ion binding]; other site 216591002173 DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986 216591002174 HMMPfam hit to PF00986, DNA gyrase B subunit, carboxyl terminus, score 5.2e-44 216591002175 HMMPfam hit to PF01751, Toprim domain, score 6.1e-06 216591002176 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002177 PS00177 DNA topoisomerase II signature. 216591002178 HMMPfam hit to PF00204, DNA gyrase B, score 2.7e-87 216591002179 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and H, score 1.2e-25 216591002180 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002181 DNA polymerase III subunit beta; Validated; Region: PRK05643 216591002182 Beta clamp domain. The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria. The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140 216591002183 putative DNA binding surface [nucleotide binding]; other site 216591002184 dimer interface [polypeptide binding]; other site 216591002185 beta-clamp/clamp loader binding surface; other site 216591002186 beta-clamp/translesion DNA polymerase binding surface; other site 216591002187 HMMPfam hit to PF02768, DNA polymerase III beta subunit, C-te, score 2e-39 216591002188 HMMPfam hit to PF02767, DNA polymerase III beta subunit, cent, score 7.3e-43 216591002189 HMMPfam hit to PF00712, DNA polymerase III beta subunit, N-te, score 2.3e-29 216591002190 DnaA N-terminal domain; Region: DnaA_N; pfam11638 216591002191 chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149 216591002192 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591002193 Walker A motif; other site 216591002194 ATP binding site [chemical binding]; other site 216591002195 Walker B motif; other site 216591002196 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189 216591002197 arginine finger; other site 216591002198 C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571 216591002199 DnaA box-binding interface [nucleotide binding]; other site 216591002200 HMMPfam hit to PF08299, Bacterial dnaA protein helix-turn-helix, score 9e-43 216591002201 PS01008 DnaA protein signature. 216591002202 HMMPfam hit to PF00308, Bacterial dnaA protein, score 1.5e-120 216591002203 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002204 50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399 216591002205 Ribonuclease P; Region: Ribonuclease_P; cl00457 216591002206 hypothetical protein; Validated; Region: PRK00041 216591002207 HMMPfam hit to PF01809, Domain of unknown function DUF37, score 6.7e-33 216591002208 membrane protein insertase; Provisional; Region: PRK01318 216591002209 membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592 216591002210 4 probable transmembrane helices predicted for BCAL0426 by TMHMM2.0 at aa 7-24, 364-386, 429-451 and 506-528 216591002211 HMMPfam hit to PF02096, 60Kd inner membrane protein, score 1.8e-105 216591002212 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591002213 non-specific DNA binding site [nucleotide binding]; other site 216591002214 salt bridge; other site 216591002215 sequence-specific DNA binding site [nucleotide binding]; other site 216591002216 tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291 216591002217 GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396 216591002218 trmE is a tRNA modification GTPase; Region: trmE; cd04164 216591002219 G1 box; other site 216591002220 GTP/Mg2+ binding site [chemical binding]; other site 216591002221 Switch I region; other site 216591002222 G2 box; other site 216591002223 Switch II region; other site 216591002224 G3 box; other site 216591002225 G4 box; other site 216591002226 G5 box; other site 216591002227 Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631 216591002228 HMMPfam hit to PF01926, GTPase of unknown function, score 2.6e-43 216591002229 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002230 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591002231 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591002232 metal binding site [ion binding]; metal-binding site 216591002233 active site 216591002234 I-site; other site 216591002235 HMMPfam hit to PF00990, GGDEF domain, score 2.4e-59 216591002236 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591002237 7 probable transmembrane helices predicted for BCAL0430 by TMHMM2.0 at aa 13-35, 50-68, 75-97, 112-134, 154-176, 191-213 and 248-270 216591002238 Protein of unknown function (DUF2795); Region: DUF2795; pfam11387 216591002239 1 probable transmembrane helix predicted for BCAL0432 by TMHMM2.0 at aa 5-22 216591002240 spermidine N1-acetyltransferase; Provisional; Region: PRK15130 216591002241 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591002242 Coenzyme A binding pocket [chemical binding]; other site 216591002243 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.2e-19 216591002244 YaeQ protein; Region: YaeQ; pfam07152 216591002245 HMMPfam hit to PF07152, YaeQ protein, score 1.8e-104 216591002246 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253 216591002247 dimer interface [polypeptide binding]; other site 216591002248 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591002249 metal binding site [ion binding]; metal-binding site 216591002250 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 3e-15 216591002251 bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435 216591002252 Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805 216591002253 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591002254 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870 216591002255 The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445 216591002256 DNA binding site [nucleotide binding] 216591002257 active site 216591002258 HMMPfam hit to PF02805, Metal binding domain of Ada, score 4e-41 216591002259 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix, score 2.3e-10 216591002260 Predicted helix-turn-helix motif with score 1844.000, SD 5.47 at aa 97-118, sequence LTLQQLSDAVHVSPFHLQRLFK 216591002261 HMMPfam hit to PF02870, 6-O-methylguanine DNA methyltransfera, score 1.6e-12 216591002262 HMMPfam hit to PF01035, 6-O-methylguanine DNA methyltransfera, score 2.4e-47 216591002263 PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 216591002264 AlkA N-terminal domain; Region: AlkA_N; pfam06029 216591002265 3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308 216591002266 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 216591002267 minor groove reading motif; other site 216591002268 helix-hairpin-helix signature motif; other site 216591002269 substrate binding pocket [chemical binding]; other site 216591002270 active site 216591002271 HMMPfam hit to PF06029, AlkA N-terminal domain, score 3e-27 216591002272 HMMPfam hit to PF00730, HhH-GPD superfamily base excision DNA repair, score 5.6e-10 216591002273 glutamate--cysteine ligase; Provisional; Region: PRK02107 216591002274 HMMPfam hit to PF04262, Glutamate-cysteine ligase, score 1e-196 216591002275 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591002276 1 probable transmembrane helix predicted for BCAL0440 by TMHMM2.0 at aa 7-25 216591002277 L-lactate permease [Energy production and conversion]; Region: LldP; COG1620 216591002278 L-lactate permease; Region: Lactate_perm; cl00701 216591002279 13 probable transmembrane helices predicted for BCAL0441 by TMHMM2.0 at aa 20-42, 49-68, 83-105, 126-148, 152-174, 179-201, 206-228, 235-257, 307-329, 354-376, 396-418, 425-447 and 510-532 216591002280 HMMPfam hit to PF02652, L-lactate permease, score 6.8e-127 216591002281 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002282 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591002283 aminoethylphosphonate catabolism associated LysR family transcriptional regulator; Region: phn_lysR; TIGR03339 216591002284 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591002285 dimerization interface [polypeptide binding]; other site 216591002286 HMMPfam hit to PF03466, LysR substrate binding domain, score 8.2e-43 216591002287 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.4e-20 216591002288 PS00044 Bacterial regulatory proteins, lysR family signature. 216591002289 Predicted helix-turn-helix motif with score 2007.000, SD 6.02 at aa 15-36, sequence GSITRAARHLGVSQPTIAAQIR 216591002290 phospholipase C, phosphocholine-specific, Pseudomonas-type; Region: PC_PLC; TIGR03396 216591002291 Phosphoesterase family; Region: Phosphoesterase; pfam04185 216591002292 Domain of unknown function (DUF756); Region: DUF756; pfam05506 216591002293 Domain of unknown function (DUF756); Region: DUF756; pfam05506 216591002294 HMMPfam hit to PF04185, Phosphoesterase family, score 3.2e-125 216591002295 HMMPfam hit to PF05506, Domain of unknown function (DUF756), score 1.3e-26 216591002296 HMMPfam hit to PF05506, Domain of unknown function (DUF756), score 8.3e-24 216591002297 PS00192 Cytochrome b/b6 heme-ligand signature. 216591002298 phosphonate utilization associated transcriptional regulator; Region: phnR_burk; TIGR03338 216591002299 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591002300 DNA-binding site [nucleotide binding]; DNA binding site 216591002301 FCD domain; Region: FCD; pfam07729 216591002302 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 3.7e-18 216591002303 PS00043 Bacterial regulatory proteins, gntR family signature. 216591002304 Predicted helix-turn-helix motif with score 1208.000, SD 3.30 at aa 41-62, sequence LNEVEIATRLNVSRGPVREAFR 216591002305 HMMPfam hit to PF07729, FCD domain, score 1.4e-26 216591002306 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591002307 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591002308 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1e-80 216591002309 2-aminoethylphosphonate--pyruvate transaminase; Provisional; Region: PRK13479 216591002310 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591002311 catalytic residue [active] 216591002312 HMMPfam hit to PF00266, Aminotransferase class-V, score 4.6e-08 216591002313 putative 2-aminoethylphosphonate ABC transporter, permease protein; Region: PhnU2; TIGR03262 216591002314 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591002315 dimer interface [polypeptide binding]; other site 216591002316 conserved gate region; other site 216591002317 putative PBP binding loops; other site 216591002318 ABC-ATPase subunit interface; other site 216591002319 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591002320 dimer interface [polypeptide binding]; other site 216591002321 conserved gate region; other site 216591002322 putative PBP binding loops; other site 216591002323 ABC-ATPase subunit interface; other site 216591002324 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.00031 216591002325 12 probable transmembrane helices predicted for BCAL0447 by TMHMM2.0 at aa 31-53, 85-107, 120-142, 162-184, 204-226, 261-283, 310-332, 364-386, 399-421, 436-458, 479-501 and 537-559 216591002326 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.00096 216591002327 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591002328 putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; Region: PhnT2; TIGR03265 216591002329 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591002330 Walker A/P-loop; other site 216591002331 ATP binding site [chemical binding]; other site 216591002332 Q-loop/lid; other site 216591002333 ABC transporter signature motif; other site 216591002334 Walker B; other site 216591002335 D-loop; other site 216591002336 H-loop/switch region; other site 216591002337 TOBE domain; Region: TOBE_2; pfam08402 216591002338 HMMPfam hit to PF08402, TOBE domain, score 5.8e-11 216591002339 HMMPfam hit to PF03459, TOBE domain, score 0.00056 216591002340 HMMPfam hit to PF00005, ABC transporter, score 2.5e-63 216591002341 PS00211 ABC transporters family signature. 216591002342 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002343 ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143 216591002344 putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein; Region: phnS2; TIGR03261 216591002345 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 1.6e-08 216591002346 1 probable transmembrane helix predicted for BCAL0449 by TMHMM2.0 at aa 13-35 216591002347 phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335 216591002348 Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663 216591002349 HMMPfam hit to PF01663, Type I phosphodiesterase / nucleotide py, score 7.5e-17 216591002350 putative phosphonoacetaldehyde dehydrogenase; Region: PhnAcAld_DH; TIGR03250 216591002351 Streptomyces putative phosphonoformaldehyde dehydrogenase PhpJ-like; Region: ALDH_PhpJ; cd07146 216591002352 NAD(P) binding site [chemical binding]; other site 216591002353 catalytic residues [active] 216591002354 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 3.6e-178 216591002355 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002356 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591002357 PS00070 Aldehyde dehydrogenases cysteine active site. 216591002358 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591002359 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591002360 substrate binding pocket [chemical binding]; other site 216591002361 membrane-bound complex binding site; other site 216591002362 hinge residues; other site 216591002363 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 4.9e-99 216591002364 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591002365 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591002366 dimer interface [polypeptide binding]; other site 216591002367 conserved gate region; other site 216591002368 putative PBP binding loops; other site 216591002369 ABC-ATPase subunit interface; other site 216591002370 3 probable transmembrane helices predicted for BCAL0453 by TMHMM2.0 at aa 15-37, 58-80 and 188-207 216591002371 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.1e-28 216591002372 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 216591002373 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591002374 Walker A/P-loop; other site 216591002375 ATP binding site [chemical binding]; other site 216591002376 Q-loop/lid; other site 216591002377 ABC transporter signature motif; other site 216591002378 Walker B; other site 216591002379 D-loop; other site 216591002380 H-loop/switch region; other site 216591002381 HMMPfam hit to PF00005, ABC transporter, score 5.2e-64 216591002382 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002383 PS00211 ABC transporters family signature. 216591002384 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591002385 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 6.8e-11 216591002386 Protein of unknown function (DUF1470); Region: DUF1470; pfam07336 216591002387 CGNR zinc finger; Region: zf-CGNR; pfam11706 216591002388 HMMPfam hit to PF07336, Protein of unknown function (DUF1470), score 8.3e-18 216591002389 Protein of unknown function (DUF3592); Region: DUF3592; pfam12158 216591002390 Protein of unknown function (DUF3592); Region: DUF3592; pfam12158 216591002391 4 probable transmembrane helices predicted for BCAL0457 by TMHMM2.0 at aa 7-29, 109-131, 157-179 and 266-288 216591002392 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 216591002393 Thioesterase-like superfamily; Region: 4HBT_3; pfam13622 216591002394 CoenzymeA binding site [chemical binding]; other site 216591002395 subunit interaction site [polypeptide binding]; other site 216591002396 PHB binding site; other site 216591002397 HMMPfam hit to PF03061, Thioesterase superfamily, score 2.2e-15 216591002398 Patatin-like phospholipase; Region: Patatin; pfam01734 216591002399 active site 216591002400 nucleophile elbow; other site 216591002401 Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396 216591002402 HMMPfam hit to PF01734, Patatin-like phospholipase, score 6.3e-06 216591002403 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002404 Putative D-3-Phosphoglycerate Dehydrogenases; Region: PGDH_like_1; cd12169 216591002405 Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111 216591002406 dimerization interface [polypeptide binding]; other site 216591002407 NAD binding site [chemical binding]; other site 216591002408 ligand binding site [chemical binding]; other site 216591002409 catalytic site [active] 216591002410 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 8.4e-20 216591002411 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 8.1e-67 216591002412 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591002413 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591002414 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591002415 putative effector binding pocket; other site 216591002416 dimerization interface [polypeptide binding]; other site 216591002417 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.3e-18 216591002418 PS00044 Bacterial regulatory proteins, lysR family signature. 216591002419 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.4e-51 216591002420 DNA topoisomerase III; Validated; Region: PRK08173 216591002421 TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362 216591002422 active site 216591002423 putative interdomain interaction site [polypeptide binding]; other site 216591002424 putative metal-binding site [ion binding]; other site 216591002425 putative nucleotide binding site [chemical binding]; other site 216591002426 DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186 216591002427 domain I; other site 216591002428 DNA binding groove [nucleotide binding] 216591002429 phosphate binding site [ion binding]; other site 216591002430 domain II; other site 216591002431 domain III; other site 216591002432 nucleotide binding site [chemical binding]; other site 216591002433 catalytic site [active] 216591002434 domain IV; other site 216591002435 C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342 216591002436 C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342 216591002437 HMMPfam hit to PF01131, DNA topoisomerase, score 1.8e-100 216591002438 PS00396 Prokaryotic DNA topoisomerase I active site. 216591002439 HMMPfam hit to PF01751, Toprim domain, score 2.6e-14 216591002440 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 216591002441 catalytic residues [active] 216591002442 HMMPfam hit to PF00085, Thioredoxin, score 0.015 216591002443 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758 216591002444 DNA protecting protein DprA; Region: dprA; TIGR00732 216591002445 HMMPfam hit to PF02481, SMF family, score 2.5e-91 216591002446 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002447 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 216591002448 active site 216591002449 catalytic residues [active] 216591002450 metal binding site [ion binding]; metal-binding site 216591002451 HMMPfam hit to PF01327, Polypeptide deformylase, score 1.6e-71 216591002452 methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005 216591002453 Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646 216591002454 putative active site [active] 216591002455 substrate binding site [chemical binding]; other site 216591002456 putative cosubstrate binding site; other site 216591002457 catalytic site [active] 216591002458 C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704 216591002459 substrate binding site [chemical binding]; other site 216591002460 HMMPfam hit to PF00551, Formyl transferase, score 4.7e-49 216591002461 HMMPfam hit to PF02911, Formyl transferase, C-terminal domain, score 4e-29 216591002462 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591002463 5 probable transmembrane helices predicted for BCAL0467 by TMHMM2.0 at aa 4-21, 41-63, 67-89, 121-143 and 153-175 216591002464 HMMPfam hit to PF01810, LysE type translocator, score 1.8e-36 216591002465 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002466 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591002467 M48 family peptidase; Provisional; Region: PRK03001 216591002468 4 probable transmembrane helices predicted for BCAL0468 by TMHMM2.0 at aa 7-26, 30-49, 142-164 and 174-193 216591002469 HMMPfam hit to PF01435, Peptidase family M48, score 1e-22 216591002470 16S rRNA methyltransferase B; Provisional; Region: PRK10901 216591002471 RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223 216591002472 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591002473 S-adenosylmethionine binding site [chemical binding]; other site 216591002474 HMMPfam hit to PF01189, NOL1/NOP2/sun family, score 3.3e-65 216591002475 PS01153 NOL1/NOP2/sun family signature. 216591002476 Domain of unknown function (DUF4390); Region: DUF4390; pfam14334 216591002477 1 probable transmembrane helix predicted for BCAL0470 by TMHMM2.0 at aa 7-29 216591002478 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591002479 dimerization interface [polypeptide binding]; other site 216591002480 PAS domain; Region: PAS; smart00091 216591002481 Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852 216591002482 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591002483 dimer interface [polypeptide binding]; other site 216591002484 phosphorylation site [posttranslational modification] 216591002485 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591002486 ATP binding site [chemical binding]; other site 216591002487 Mg2+ binding site [ion binding]; other site 216591002488 G-X-G motif; other site 216591002489 4 probable transmembrane helices predicted for BCAL0471 by TMHMM2.0 at aa 5-27, 39-58, 73-95 and 297-319 216591002490 HMMPfam hit to PF00672, HAMP domain, score 5.3e-16 216591002491 HMMPfam hit to PF08448, PAS fold, score 0.0012 216591002492 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5.3e-09 216591002493 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 7.9e-28 216591002494 Response regulator receiver domain; Region: Response_reg; pfam00072 216591002495 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591002496 active site 216591002497 phosphorylation site [posttranslational modification] 216591002498 intermolecular recognition site; other site 216591002499 dimerization interface [polypeptide binding]; other site 216591002500 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.8e-36 216591002501 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis family, score 0.0028 216591002502 Predicted helix-turn-helix motif with score 1531.000, SD 4.40 at aa 197-218, sequence GSMRRVAEKTGLERTHLYRKLK 216591002503 ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995 216591002504 Ligand Binding Site [chemical binding]; other site 216591002505 HMMPfam hit to PF06508, ExsB, score 1.8e-88 216591002506 Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602 216591002507 putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322 216591002508 6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242 216591002509 active site 216591002510 HMMPfam hit to PF01242, 6-pyruvoyl tetrahydropterin synthase, score 4.7e-06 216591002511 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism]; Region: HpcH; COG3836 216591002512 HMMPfam hit to PF03328, HpcH/HpaI aldolase/citrate lyase family, score 1.3e-72 216591002513 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591002514 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 216591002515 Sel1-like repeats; Region: SEL1; smart00671 216591002516 Sel1-like repeats; Region: SEL1; smart00671 216591002517 Sel1-like repeats; Region: SEL1; smart00671 216591002518 HMMPfam hit to PF08238, Sel1 repeat, score 1.3e-07 216591002519 HMMPfam hit to PF08238, Sel1 repeat, score 2.1e-09 216591002520 HMMPfam hit to PF08238, Sel1 repeat, score 8.5e-07 216591002521 HMMPfam hit to PF08238, Sel1 repeat, score 2.7e-06 216591002522 rod shape-determining protein RodA; Region: rodA_shape; TIGR02210 216591002523 HMMPfam hit to PF01098, Cell cycle protein, score 1e-123 216591002524 8 probable transmembrane helices predicted for BCAL0478 by TMHMM2.0 at aa 21-43, 73-95, 135-157, 162-181, 186-203, 286-308, 315-337 and 352-374 216591002525 PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 216591002526 penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423 216591002527 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 216591002528 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 216591002529 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 5.6e-83 216591002530 HMMPfam hit to PF03717, Penicillin-binding Protein dimerisatio, score 8.8e-47 216591002531 1 probable transmembrane helix predicted for BCAL0479 by TMHMM2.0 at aa 20-39 216591002532 Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreD; COG2891 216591002533 HMMPfam hit to PF04093, rod shape-determining protein MreD, score 6e-11 216591002534 3 probable transmembrane helices predicted for BCAL0480 by TMHMM2.0 at aa 13-32, 80-99 and 106-128 216591002535 Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792 216591002536 rod shape-determining protein MreC; Region: MreC; pfam04085 216591002537 HMMPfam hit to PF04085, rod shape-determining protein MreC, score 2.7e-33 216591002538 1 probable transmembrane helix predicted for BCAL0481 by TMHMM2.0 at aa 15-32 216591002539 rod shape-determining protein MreB; Provisional; Region: PRK13927 216591002540 MreB and similar proteins; Region: MreB_like; cd10225 216591002541 nucleotide binding site [chemical binding]; other site 216591002542 Mg binding site [ion binding]; other site 216591002543 putative protofilament interaction site [polypeptide binding]; other site 216591002544 RodZ interaction site [polypeptide binding]; other site 216591002545 HMMPfam hit to PF06723, MreB/Mbl protein, score 6.7e-231 216591002546 aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034 216591002547 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154 216591002548 aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012 216591002549 HMMPfam hit to PF01425, Amidase, score 1.4e-184 216591002550 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002551 PS00571 Amidases signature. 216591002552 aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477 216591002553 GatB/GatE catalytic domain; Region: GatB_N; pfam02934 216591002554 GatB domain; Region: GatB_Yqey; smart00845 216591002555 HMMPfam hit to PF02934, PET112 family, N terminal region, score 1e-146 216591002556 PS01234 PET112 family signature. 216591002557 HMMPfam hit to PF01162, PET112 family, C terminal region, score 5.2e-33 216591002558 HMMPfam hit to PF02637, GatB/Yqey domain, score 6.3e-64 216591002559 polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709 216591002560 HMMPfam hit to PF03976, Polyphosphate kinase, score 2.8e-78 216591002561 Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281 216591002562 putative active site [active] 216591002563 putative catalytic site [active] 216591002564 putative DNA binding site [nucleotide binding]; other site 216591002565 putative phosphate binding site [ion binding]; other site 216591002566 metal binding site A [ion binding]; metal-binding site 216591002567 putative AP binding site [nucleotide binding]; other site 216591002568 putative metal binding site B [ion binding]; other site 216591002569 HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 2.4e-51 216591002570 Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064 216591002571 Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283 216591002572 putative NAD(P) binding site [chemical binding]; other site 216591002573 putative substrate binding site [chemical binding]; other site 216591002574 catalytic Zn binding site [ion binding]; other site 216591002575 structural Zn binding site [ion binding]; other site 216591002576 dimer interface [polypeptide binding]; other site 216591002577 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.6e-35 216591002578 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 216591002579 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 6.8e-35 216591002580 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591002581 PS00190 Cytochrome c family heme-binding site signature. 216591002582 AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719 216591002583 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591002584 HMMPfam hit to PF06719, AraC-type transcriptional regulator N-termin, score 2.7e-68 216591002585 PS00041 Bacterial regulatory proteins, araC family signature. 216591002586 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.1e-06 216591002587 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.0012 216591002588 Peptidase family M48; Region: Peptidase_M48; cl12018 216591002589 HMMPfam hit to PF01435, Peptidase family M48, score 2.5e-14 216591002590 muropeptide transporter; Reviewed; Region: ampG; PRK11902 216591002591 AmpG-like permease; Region: 2A0125; TIGR00901 216591002592 12 probable transmembrane helices predicted for BCAL0491 by TMHMM2.0 at aa 31-53, 63-80, 100-119, 124-146, 167-184, 189-211, 242-261, 281-303, 310-329, 339-361, 374-396 and 434-456 216591002593 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4e-10 216591002594 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 216591002595 HMMPfam hit to PF07021, Methionine biosynthesis protein MetW, score 2e-118 216591002596 HMMPfam hit to PF08241, Methyltransferase domain, score 5.3e-07 216591002597 HMMPfam hit to PF08242, Methyltransferase domain, score 7.4e-06 216591002598 homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175 216591002599 homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392 216591002600 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.4e-13 216591002601 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591002602 division inhibitor protein; Provisional; Region: slmA; PRK09480 216591002603 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591002604 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.4e-06 216591002605 Predicted helix-turn-helix motif with score 1850.000, SD 5.49 at aa 48-69, sequence ITTAALAARLDVSEAALYRHFT 216591002606 pyrimidine 5'-nucleotidase; Region: Pyr-5-nucltdase; TIGR01993 216591002607 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.3e-08 216591002608 AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250 216591002609 feedback inhibition sensing region; other site 216591002610 homohexameric interface [polypeptide binding]; other site 216591002611 nucleotide binding site [chemical binding]; other site 216591002612 N-acetyl-L-glutamate binding site [chemical binding]; other site 216591002613 HMMPfam hit to PF00696, Amino acid kinase family, score 9.1e-50 216591002614 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591002615 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591002616 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591002617 dimer interface [polypeptide binding]; other site 216591002618 phosphorylation site [posttranslational modification] 216591002619 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591002620 ATP binding site [chemical binding]; other site 216591002621 Mg2+ binding site [ion binding]; other site 216591002622 G-X-G motif; other site 216591002623 5 probable transmembrane helices predicted for BCAL0497 by TMHMM2.0 at aa 16-38, 43-65, 72-94, 114-136 and 156-173 216591002624 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002625 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 6.2e-05 216591002626 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.6e-21 216591002627 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain [Signal transduction mechanisms / Transcription]; Region: COG4567 216591002628 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591002629 active site 216591002630 phosphorylation site [posttranslational modification] 216591002631 intermolecular recognition site; other site 216591002632 dimerization interface [polypeptide binding]; other site 216591002633 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591002634 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.2e-21 216591002635 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis family, score 1.5e-09 216591002636 Predicted helix-turn-helix motif with score 1579.000, SD 4.56 at aa 153-174, sequence NNISATARALNMHRRTLQRKLA 216591002637 ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201 216591002638 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591002639 Walker A motif; other site 216591002640 ATP binding site [chemical binding]; other site 216591002641 AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724 216591002642 Walker B motif; other site 216591002643 arginine finger; other site 216591002644 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 216591002645 HMMPfam hit to PF07724, ATPase family associated with various cellul, score 1.3e-51 216591002646 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002647 Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913 216591002648 active site 216591002649 HslU subunit interaction site [polypeptide binding]; other site 216591002650 HMMPfam hit to PF00227, Proteasome A-type and B-type, score 5.7e-32 216591002651 RNA polymerase-binding protein DksA; Region: dksA; TIGR02420 216591002652 HMMPfam hit to PF01258, Prokaryotic dksA/traR C4-type zinc finge, score 6.6e-13 216591002653 Putative GTPases (G3E family) [General function prediction only]; Region: COG0523 216591002654 The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112 216591002655 P-loop, Walker A motif; other site 216591002656 Base recognition motif; other site 216591002657 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683 216591002658 HMMPfam hit to PF07683, Cobalamin synthesis protein cobW C-terminal, score 3.2e-33 216591002659 HMMPfam hit to PF02492, CobW/HypB/UreG, nucleotide-binding domain, score 1.4e-76 216591002660 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002661 Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092 216591002662 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359 216591002663 Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572 216591002664 putative RNA binding site [nucleotide binding]; other site 216591002665 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591002666 S-adenosylmethionine binding site [chemical binding]; other site 216591002667 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002668 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236 216591002669 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 216591002670 active site 216591002671 DNA binding site [nucleotide binding] 216591002672 Int/Topo IB signature motif; other site 216591002673 HMMPfam hit to PF00589, Phage integrase family, score 1.4e-39 216591002674 HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like, score 1.6e-19 216591002675 Protein of unknown function, DUF484; Region: DUF484; cl17449 216591002676 HMMPfam hit to PF04340, Protein of unknown function, DUF484, score 5.4e-12 216591002677 diaminopimelate epimerase; Provisional; Region: dapF; PRK00450 216591002678 Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678 216591002679 Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678 216591002680 HMMPfam hit to PF01678, Diaminopimelate epimerase, score 2.4e-40 216591002681 HMMPfam hit to PF01678, Diaminopimelate epimerase, score 8.2e-46 216591002682 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984 216591002683 putative acyl-acceptor binding pocket; other site 216591002684 HMMPfam hit to PF03279, Bacterial lipid A biosynthesis acyltr, score 3.1e-40 216591002685 S-adenosylmethionine synthetase; Validated; Region: PRK05250 216591002686 S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438 216591002687 S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772 216591002688 S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773 216591002689 HMMPfam hit to PF00438, S-adenosylmethionine synthetase, N-te, score 3.8e-51 216591002690 HMMPfam hit to PF02772, S-adenosylmethionine synthetase, cent, score 3.8e-72 216591002691 PS00376 S-adenosylmethionine synthetase signature 1. 216591002692 HMMPfam hit to PF02773, S-adenosylmethionine synthetase, C-te, score 9.1e-87 216591002693 PS00377 S-adenosylmethionine synthetase signature 2. 216591002694 Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312 216591002695 HMMPfam hit to PF05721, Phytanoyl-CoA dioxygenase (PhyH), score 4.4e-36 216591002696 Protein of unknown function (DUF3185); Region: DUF3185; pfam11381 216591002697 2 probable transmembrane helices predicted for BCAL0512 by TMHMM2.0 at aa 5-24 and 44-66 216591002698 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591002699 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 216591002700 active site 216591002701 catalytic tetrad [active] 216591002702 HMMPfam hit to PF00248, Aldo/keto reductase family, score 1.3e-74 216591002703 2 probable transmembrane helices predicted for BCAL0514 by TMHMM2.0 at aa 5-27 and 40-59 216591002704 EamA-like transporter family; Region: EamA; pfam00892 216591002705 10 probable transmembrane helices predicted for BCAL0515 by TMHMM2.0 at aa 7-26, 36-58, 71-90, 94-115, 122-144, 148-170, 182-204, 208-230, 239-261 and 266-288 216591002706 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.1e-15 216591002707 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002708 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.1e-07 216591002709 Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334 216591002710 serine/threonine protein kinase; Provisional; Region: PRK11768 216591002711 HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 2e-31 216591002712 NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012 216591002713 Coniferyl aldehyde dehydrogenase-like; Region: ALDH_CALDH_CalB; cd07133 216591002714 NAD(P) binding site [chemical binding]; other site 216591002715 catalytic residues [active] 216591002716 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 2.4e-56 216591002717 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591002718 choline dehydrogenase; Validated; Region: PRK02106 216591002719 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 216591002720 HMMPfam hit to PF00732, GMC oxidoreductase, score 1e-99 216591002721 PS00624 GMC oxidoreductases signature 2. 216591002722 HMMPfam hit to PF05199, GMC oxidoreductase, score 2.9e-54 216591002723 Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120 216591002724 HMMPfam hit to PF02120, Flagellar hook-length control protein, score 1.7e-19 216591002725 Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882 216591002726 flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689 216591002727 HMMPfam hit to PF02050, Flagellar FliJ protein, score 2.1e-11 216591002728 flagellar protein export ATPase FliI; Region: FliI_clade1; TIGR03496 216591002729 Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136 216591002730 Walker A motif/ATP binding site; other site 216591002731 Walker B motif; other site 216591002732 HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleotid, score 2.2e-120 216591002733 PS00152 ATP synthase alpha and beta subunits signature. 216591002734 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002735 flagellar assembly protein H; Validated; Region: fliH; PRK05687 216591002736 Flagellar assembly protein FliH; Region: FliH; pfam02108 216591002737 HMMPfam hit to PF02108, Flagellar assembly protein FliH, score 3.2e-15 216591002738 flagellar motor switch protein G; Validated; Region: fliG; PRK05686 216591002739 FliG C-terminal domain; Region: FliG_C; pfam01706 216591002740 HMMPfam hit to PF01706, FliG C-terminal domain, score 1.5e-53 216591002741 flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007 216591002742 Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514 216591002743 Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345 216591002744 HMMPfam hit to PF08345, Flagellar M-ring protein C-terminal, score 6e-94 216591002745 HMMPfam hit to PF01514, Secretory protein of YscJ/FliF family, score 1.6e-81 216591002746 1 probable transmembrane helix predicted for BCAL0525 by TMHMM2.0 at aa 60-79 216591002747 Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139 216591002748 HMMPfam hit to PF02049, Flagellar hook-basal body complex protein Fl, score 1.3e-25 216591002749 Flagellar protein FliS; Region: FliS; cl00654 216591002750 HMMPfam hit to PF02561, Flagellar protein FliS, score 7.4e-27 216591002751 Flagellar protein FliT; Region: FliT; cl05125 216591002752 Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120 216591002753 PS00012 Phosphopantetheine attachment site. 216591002754 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257 216591002755 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3295 216591002756 HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.14 216591002757 3 probable transmembrane helices predicted for BCAL0531 by TMHMM2.0 at aa 53-75, 195-217 and 226-243 216591002758 HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.38 216591002759 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975 216591002760 XdhC and CoxI family; Region: XdhC_CoxI; pfam02625 216591002761 XdhC Rossmann domain; Region: XdhC_C; pfam13478 216591002762 HMMPfam hit to PF02625, XdhC and CoxI family, score 3.5e-19 216591002763 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002764 amino acid transporter; Region: 2A0306; TIGR00909 216591002765 C-terminus of AA_permease; Region: AA_permease_C; pfam13906 216591002766 HMMPfam hit to PF00324, Amino acid permease, score 3.7e-27 216591002767 12 probable transmembrane helices predicted for BCAL0533 by TMHMM2.0 at aa 30-52, 57-76, 83-105, 154-176, 183-205, 220-242, 255-277, 301-323, 349-371, 375-397, 410-429 and 434-453 216591002768 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002769 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002770 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591002771 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591002772 active site 216591002773 phosphorylation site [posttranslational modification] 216591002774 intermolecular recognition site; other site 216591002775 dimerization interface [polypeptide binding]; other site 216591002776 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591002777 DNA binding residues [nucleotide binding] 216591002778 dimerization interface [polypeptide binding]; other site 216591002779 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 4.2e-12 216591002780 Predicted helix-turn-helix motif with score 1219.000, SD 3.34 at aa 165-186, sequence KRLTDIANTLSLSVKTVSVYRS 216591002781 HMMPfam hit to PF00072, Response regulator receiver domain, score 4.9e-38 216591002782 Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581 216591002783 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591002784 ATP binding site [chemical binding]; other site 216591002785 Mg2+ binding site [ion binding]; other site 216591002786 G-X-G motif; other site 216591002787 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 9.7e-18 216591002788 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018 216591002789 Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195 216591002790 FAD binding pocket [chemical binding]; other site 216591002791 FAD binding motif [chemical binding]; other site 216591002792 phosphate binding motif [ion binding]; other site 216591002793 beta-alpha-beta structure motif; other site 216591002794 NAD binding pocket [chemical binding]; other site 216591002795 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 0.00081 216591002796 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 0.00059 216591002797 Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490 216591002798 putative catalytic site [active] 216591002799 putative phosphate binding site [ion binding]; other site 216591002800 putative metal binding site [ion binding]; other site 216591002801 HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 9.7e-10 216591002802 Nitroreductase family. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source...; Region: Nitroreductase; cd02136 216591002803 putative FMN binding site [chemical binding]; other site 216591002804 HMMPfam hit to PF00881, Nitroreductase family, score 3.9e-22 216591002805 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591002806 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591002807 ATP binding site [chemical binding]; other site 216591002808 Walker B motif; other site 216591002809 arginine finger; other site 216591002810 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 4.5e-15 216591002811 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 2e-06 216591002812 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002813 Predicted dehydrogenase [General function prediction only]; Region: COG0579 216591002814 hydroxyglutarate oxidase; Provisional; Region: PRK11728 216591002815 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 5.9e-73 216591002816 High potential iron-sulfur protein; Region: HIPIP; pfam01355 216591002817 HMMPfam hit to PF01355, High potential iron-sulfur protein, score 1.3e-25 216591002818 PS00596 High potential iron-sulfur proteins signature. 216591002819 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591002820 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591002821 putative substrate translocation pore; other site 216591002822 HMMPfam hit to PF00083, Sugar (and other) transporter, score 1.3e-26 216591002823 12 probable transmembrane helices predicted for BCAL0543 by TMHMM2.0 at aa 21-43, 63-85, 92-111, 115-137, 158-180, 195-212, 249-271, 281-303, 310-330, 340-362, 375-397 and 407-426 216591002824 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.4e-21 216591002825 PS00217 Sugar transport proteins signature 2. 216591002826 PS00216 Sugar transport proteins signature 1. 216591002827 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 216591002828 The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493 216591002829 peptide binding site [polypeptide binding]; other site 216591002830 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 2.3e-87 216591002831 PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 216591002832 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 216591002833 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591002834 dimer interface [polypeptide binding]; other site 216591002835 conserved gate region; other site 216591002836 putative PBP binding loops; other site 216591002837 ABC-ATPase subunit interface; other site 216591002838 6 probable transmembrane helices predicted for BCAL0545 by TMHMM2.0 at aa 9-31, 100-122, 143-165, 198-220, 256-278 and 306-328 216591002839 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 8.3e-63 216591002840 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591002841 dipeptide transporter; Provisional; Region: PRK10913 216591002842 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591002843 dimer interface [polypeptide binding]; other site 216591002844 conserved gate region; other site 216591002845 putative PBP binding loops; other site 216591002846 ABC-ATPase subunit interface; other site 216591002847 5 probable transmembrane helices predicted for BCAL0546 by TMHMM2.0 at aa 34-56, 106-128, 143-165, 226-248 and 268-290 216591002848 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 8.1e-51 216591002849 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591002850 dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022 216591002851 Walker A/P-loop; other site 216591002852 ATP binding site [chemical binding]; other site 216591002853 Q-loop/lid; other site 216591002854 ABC transporter signature motif; other site 216591002855 Walker B; other site 216591002856 D-loop; other site 216591002857 H-loop/switch region; other site 216591002858 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 216591002859 HMMPfam hit to PF00005, ABC transporter, score 9e-61 216591002860 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002861 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 7.9e-25 216591002862 dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308 216591002863 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591002864 Walker A/P-loop; other site 216591002865 ATP binding site [chemical binding]; other site 216591002866 Q-loop/lid; other site 216591002867 ABC transporter signature motif; other site 216591002868 Walker B; other site 216591002869 D-loop; other site 216591002870 H-loop/switch region; other site 216591002871 oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727 216591002872 HMMPfam hit to PF00005, ABC transporter, score 1.1e-65 216591002873 PS00017 ATP/GTP-binding site motif A (P-loop). 216591002874 PS00211 ABC transporters family signature. 216591002875 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 4.7e-30 216591002876 TraB family; Region: TraB; pfam01963 216591002877 HMMPfam hit to PF07446, GumN protein, score 1.3e-18 216591002878 Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800 216591002879 putative active site [active] 216591002880 HMMPfam hit to PF03746, LamB/YcsF family, score 3.7e-138 216591002881 Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984 216591002882 HMMPfam hit to PF02626, Allophanate hydrolase subunit, score 2.5e-100 216591002883 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002884 Allophanate hydrolase subunit 1; Region: AHS1; smart00796 216591002885 Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049 216591002886 HMMPfam hit to PF02682, Allophanate hydrolase subunit, score 1.2e-100 216591002887 MarR family; Region: MarR_2; cl17246 216591002888 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591002889 HMMPfam hit to PF01047, MarR family, score 0.0015 216591002890 5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812 216591002891 5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360 216591002892 HMMPfam hit to PF01812, 5-formyltetrahydrofolate cyclo-ligase, score 1.9e-27 216591002893 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 216591002894 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591002895 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591002896 catalytic residue [active] 216591002897 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002898 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 4.8e-20 216591002899 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs; Region: NDUFA9_like_SDR_a; cd05271 216591002900 NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370 216591002901 putative NAD(P) binding site [chemical binding]; other site 216591002902 active site 216591002903 HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.003 216591002904 HMMPfam hit to PF05368, NmrA-like family, score 2e-05 216591002905 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 1.8e-13 216591002906 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 9.6e-08 216591002907 HMMPfam hit to PF07993, Male sterility protein, score 0.00024 216591002908 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002909 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591002910 GST_N family, unknown subfamily 1; composed of uncharacterized proteins, predominantly from bacteria, with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with...; Region: GST_N_1; cd03043 216591002911 putative C-terminal domain interface [polypeptide binding]; other site 216591002912 putative GSH binding site (G-site) [chemical binding]; other site 216591002913 putative dimer interface [polypeptide binding]; other site 216591002914 C-terminal, alpha helical domain of an unknown subfamily 3 of Glutathione S-transferases; Region: GST_C_3; cd03194 216591002915 putative N-terminal domain interface [polypeptide binding]; other site 216591002916 putative dimer interface [polypeptide binding]; other site 216591002917 putative substrate binding pocket (H-site) [chemical binding]; other site 216591002918 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 1.8e-08 216591002919 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885 216591002920 Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398 216591002921 active site 216591002922 NTP binding site [chemical binding]; other site 216591002923 metal binding triad [ion binding]; metal-binding site 216591002924 Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627 216591002925 CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cl17503 216591002926 HMMPfam hit to PF01743, Poly A polymerase family, score 2.8e-40 216591002927 HMMPfam hit to PF01966, HD domain, score 8.2e-07 216591002928 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591002929 sequence-specific DNA binding site [nucleotide binding]; other site 216591002930 salt bridge; other site 216591002931 Cupin domain; Region: Cupin_2; pfam07883 216591002932 HMMPfam hit to PF07883, Cupin domain, score 5.6e-19 216591002933 HMMPfam hit to PF01381, Helix-turn-helix, score 2.6e-08 216591002934 Predicted helix-turn-helix motif with score 1258.000, SD 3.47 at aa 21-42, sequence KTLLEVATEANLSVGFLSQVER 216591002935 Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321 216591002936 Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006 216591002937 A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279 216591002938 active site 216591002939 HMMPfam hit to PF00557, metallopeptidase family M24, score 4.3e-18 216591002940 PS00491 Aminopeptidase P and proline dipeptidase signature. 216591002941 PS00294 Prenyl group binding site (CAAX box). 216591002942 FlgN protein; Region: FlgN; pfam05130 216591002943 HMMPfam hit to PF05130, FlgN protein, score 1.8e-06 216591002944 flagellar biosynthesis anti-sigma factor FlgM; Region: FlgM_jcvi; TIGR03824 216591002945 SAF-like; Region: SAF_2; pfam13144 216591002946 SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614 216591002947 HMMPfam hit to PF03240, FlgA family, score 4.4e-40 216591002948 flagellar basal body rod protein FlgB; Provisional; Region: flgB; PRK12626 216591002949 flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182 216591002950 HMMPfam hit to PF00460, Flagella basal body rod protein, score 3.4e-07 216591002951 PS00588 Flagella basal body rod proteins signature. 216591002952 flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681 216591002953 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 216591002954 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 216591002955 HMMPfam hit to PF00460, Flagella basal body rod protein, score 1.7e-10 216591002956 PS00588 Flagella basal body rod proteins signature. 216591002957 HMMPfam hit to PF06429, Domain of unknown function (DUF1078), score 1.3e-10 216591002958 flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655 216591002959 Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963 216591002960 FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861 216591002961 HMMPfam hit to PF03963, Flagellar hook capping protein, score 3.1e-33 216591002962 flagellar hook protein FlgE; Validated; Region: flgE; PRK05682 216591002963 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 216591002964 Flagellar basal body protein FlaE; Region: FlaE; pfam07559 216591002965 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 216591002966 HMMPfam hit to PF00460, Flagella basal body rod protein, score 7.8e-10 216591002967 PS00588 Flagella basal body rod proteins signature. 216591002968 HMMPfam hit to PF07559, Flagellar basal body protein FlaE, score 7e-20 216591002969 HMMPfam hit to PF06429, Domain of unknown function (DUF1078), score 1.3e-16 216591002970 flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640 216591002971 flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490 216591002972 HMMPfam hit to PF00460, Flagella basal body rod protein, score 2.5e-10 216591002973 PS00588 Flagella basal body rod proteins signature. 216591002974 HMMPfam hit to PF06429, Domain of unknown function (DUF1078), score 3.8e-05 216591002975 flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12694 216591002976 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 216591002977 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 216591002978 HMMPfam hit to PF00460, Flagella basal body rod protein, score 1.7e-13 216591002979 PS00588 Flagella basal body rod proteins signature. 216591002980 HMMPfam hit to PF06429, Domain of unknown function (DUF1078), score 5.7e-20 216591002981 flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK12697 216591002982 Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063 216591002983 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002984 HMMPfam hit to PF02107, Flagellar L-ring protein, score 9.9e-64 216591002985 flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303 216591002986 flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622 216591002987 1 probable transmembrane helix predicted for BCAL0571 by TMHMM2.0 at aa 21-43 216591002988 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002989 HMMPfam hit to PF02119, Flagellar P-ring protein, score 2.4e-186 216591002990 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591002991 flagellar rod assembly protein/muramidase FlgJ; Provisional; Region: flgJ; PRK12709 216591002992 Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951 216591002993 Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705 216591002994 HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 2.3e-39 216591002995 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 216591002996 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 216591002997 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 216591002998 Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586 216591002999 HMMPfam hit to PF01609, Transposase DDE domain, score 3.6e-32 216591003000 Flagellar regulator YcgR; Region: YcgR; pfam07317 216591003001 c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581 216591003002 PilZ domain; Region: PilZ; pfam07238 216591003003 HMMPfam hit to PF07317, YcgR protein, score 6.7e-65 216591003004 HMMPfam hit to PF07238, PilZ domain, score 1.3e-15 216591003005 flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK06945 216591003006 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 216591003007 HMMPfam hit to PF06429, Domain of unknown function (DUF1078), score 7.2e-17 216591003008 flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08870 216591003009 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 216591003010 HMMPfam hit to PF00669, Bacterial flagellin N-terminus, score 1.1e-12 216591003011 pyrimidine utilization transport protein G; Region: RutG; TIGR03616 216591003012 HMMPfam hit to PF00860, Permease family, score 4.3e-114 216591003013 11 probable transmembrane helices predicted for BCAL0578 by TMHMM2.0 at aa 53-75, 80-102, 112-134, 141-163, 173-190, 197-219, 243-265, 286-308, 323-345, 352-374 and 403-425 216591003014 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003015 PS01116 Xanthine/uracil permeases family signature. 216591003016 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591003017 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591003018 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591003019 dimerization interface [polypeptide binding]; other site 216591003020 substrate binding pocket [chemical binding]; other site 216591003021 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.8e-42 216591003022 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4e-18 216591003023 PS00044 Bacterial regulatory proteins, lysR family signature. 216591003024 Predicted helix-turn-helix motif with score 1587.000, SD 4.59 at aa 21-42, sequence ESFSAAGDELHVTHGAISRQIA 216591003025 Chromate transporter; Region: Chromate_transp; pfam02417 216591003026 HMMPfam hit to PF02417, Chromate transporter, score 4.5e-23 216591003027 4 probable transmembrane helices predicted for BCAL0580 by TMHMM2.0 at aa 25-47, 95-117, 127-149 and 162-184 216591003028 Chromate transporter; Region: Chromate_transp; pfam02417 216591003029 HMMPfam hit to PF02417, Chromate transporter, score 3.7e-17 216591003030 5 probable transmembrane helices predicted for BCAL0581 by TMHMM2.0 at aa 5-27, 47-69, 76-98, 113-135 and 156-173 216591003031 PS01036 Heat shock hsp70 proteins family signature 3. 216591003032 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003033 1 probable transmembrane helix predicted for BCAL0582 by TMHMM2.0 at aa 7-26 216591003034 Protein of unknown function (DUF1275); Region: DUF1275; pfam06912 216591003035 HMMPfam hit to PF06912, Protein of unknown function (DUF1275), score 1.3e-42 216591003036 6 probable transmembrane helices predicted for BCAL0583 by TMHMM2.0 at aa 13-35, 55-77, 90-112, 116-138, 173-195 and 199-216 216591003037 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591003038 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591003039 trimer interface [polypeptide binding]; other site 216591003040 eyelet of channel; other site 216591003041 HMMPfam hit to PF00267, Gram-negative porin, score 5.8e-05 216591003042 glutathione reductase; Validated; Region: PRK06116 216591003043 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591003044 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591003045 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 216591003046 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 7.3e-58 216591003047 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 216591003048 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 1.3e-28 216591003049 HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 7.9e-53 216591003050 Curli production assembly/transport component CsgG; Region: CsgG; pfam03783 216591003051 HMMPfam hit to PF03783, Curli production assembly/transport componen, score 4.3e-80 216591003052 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003053 PS00017 ATP/GTP-binding site motif A (P-loop). 216591003054 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4259 216591003055 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003056 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4380 216591003057 HMMPfam hit to PF05643, Putative bacterial lipoprotein (DUF799), score 4.3e-68 216591003058 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003059 putative transposase OrfB; Reviewed; Region: PHA02517 216591003060 HTH-like domain; Region: HTH_21; pfam13276 216591003061 Integrase core domain; Region: rve; pfam00665 216591003062 Integrase core domain; Region: rve_2; pfam13333 216591003063 HMMPfam hit to PF00665, Integrase core domain, score 3.8e-47 216591003064 Predicted helix-turn-helix motif with score 1108.000, SD 2.96 at aa 8-29, sequence HPVAALLKAAGLARSTFYYQLK 216591003065 PS00228 Tubulin-beta mRNA autoregulation signal. 216591003066 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591003067 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591003068 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591003069 HMMPfam hit to PF02178, AT hook motif, score 0.016 216591003070 Predicted helix-turn-helix motif with score 1069.000, SD 2.83 at aa 21-42, sequence AGTKTLAHRYGVGRTMVRRWAA 216591003071 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591003072 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591003073 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 9.4e-102 216591003074 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003075 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591003076 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591003077 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.7e-93 216591003078 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591003079 Protein of unknown function (DUF3138); Region: DUF3138; pfam11336 216591003080 Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642 216591003081 1 probable transmembrane helix predicted for BCAL0594 by TMHMM2.0 at aa 5-27 216591003082 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 216591003083 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591003084 dimer interface [polypeptide binding]; other site 216591003085 conserved gate region; other site 216591003086 putative PBP binding loops; other site 216591003087 ABC-ATPase subunit interface; other site 216591003088 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.7e-10 216591003089 7 probable transmembrane helices predicted for BCAL0595 by TMHMM2.0 at aa 10-32, 66-88, 103-125, 138-160, 180-202, 209-231 and 241-263 216591003090 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591003091 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591003092 dimer interface [polypeptide binding]; other site 216591003093 conserved gate region; other site 216591003094 putative PBP binding loops; other site 216591003095 ABC-ATPase subunit interface; other site 216591003096 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3.6e-19 216591003097 6 probable transmembrane helices predicted for BCAL0596 by TMHMM2.0 at aa 30-52, 105-127, 134-156, 186-208, 240-259 and 286-308 216591003098 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591003099 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591003100 putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607 216591003101 Walker A/P-loop; other site 216591003102 ATP binding site [chemical binding]; other site 216591003103 Q-loop/lid; other site 216591003104 ABC transporter signature motif; other site 216591003105 Walker B; other site 216591003106 D-loop; other site 216591003107 H-loop/switch region; other site 216591003108 TOBE domain; Region: TOBE_2; pfam08402 216591003109 HMMPfam hit to PF08402, TOBE domain, score 1e-22 216591003110 HMMPfam hit to PF00005, ABC transporter, score 1.8e-61 216591003111 PS00211 ABC transporters family signature. 216591003112 PS00017 ATP/GTP-binding site motif A (P-loop). 216591003113 putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682 216591003114 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 216591003115 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 3.9e-13 216591003116 putative aminotransferase; Validated; Region: PRK07480 216591003117 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591003118 inhibitor-cofactor binding pocket; inhibition site 216591003119 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591003120 catalytic residue [active] 216591003121 HMMPfam hit to PF00202, Aminotransferase class-III, score 2.2e-94 216591003122 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591003123 Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174 216591003124 Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120 216591003125 HMMPfam hit to PF00120, Glutamine synthetase, catalytic domain, score 1.5e-118 216591003126 Peptidase C26; Region: Peptidase_C26; pfam07722 216591003127 Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745 216591003128 catalytic triad [active] 216591003129 HMMPfam hit to PF07722, Peptidase C26, score 2.5e-105 216591003130 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591003131 DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943 216591003132 non-specific DNA binding site [nucleotide binding]; other site 216591003133 salt bridge; other site 216591003134 sequence-specific DNA binding site [nucleotide binding]; other site 216591003135 Cupin domain; Region: Cupin_2; pfam07883 216591003136 HMMPfam hit to PF01381, Helix-turn-helix, score 1.3e-14 216591003137 Predicted helix-turn-helix motif with score 1970.000, SD 5.90 at aa 24-45, sequence LSQRELAKRAGVTNGTISLIEQ 216591003138 HMMPfam hit to PF07883, Cupin domain, score 5e-17 216591003139 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847 216591003140 Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112 216591003141 NAD(P) binding site [chemical binding]; other site 216591003142 catalytic residues [active] 216591003143 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 2.1e-240 216591003144 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591003145 PS00070 Aldehyde dehydrogenases cysteine active site. 216591003146 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 216591003147 metal-binding site [ion binding] 216591003148 HMMPfam hit to PF00403, Heavy-metal-associated domain, score 2.2e-09 216591003149 PS01047 Heavy-metal-associated domain. 216591003150 Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473 216591003151 Iron permease FTR1 family; Region: FTR1; cl00475 216591003152 HMMPfam hit to PF03239, Iron permease FTR1 family, score 5.2e-17 216591003153 6 probable transmembrane helices predicted for BCAL0606 by TMHMM2.0 at aa 34-53, 68-87, 108-125, 150-172, 185-207 and 243-265 216591003154 PS00017 ATP/GTP-binding site motif A (P-loop). 216591003155 Predicted transcriptional regulator [Transcription]; Region: COG2944 216591003156 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591003157 non-specific DNA binding site [nucleotide binding]; other site 216591003158 salt bridge; other site 216591003159 sequence-specific DNA binding site [nucleotide binding]; other site 216591003160 Predicted helix-turn-helix motif with score 1964.000, SD 5.88 at aa 60-81, sequence VSQSVFALYLNTTTSTIRQWEQ 216591003161 Protein of unknown function (DUF1044); Region: DUF1044; pfam06296 216591003162 HMMPfam hit to PF06296, Protein of unknown function (DUF1044), score 1.5e-46 216591003163 glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331 216591003164 Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans). The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714 216591003165 glutaminase active site [active] 216591003166 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 216591003167 dimer interface [polypeptide binding]; other site 216591003168 active site 216591003169 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 216591003170 dimer interface [polypeptide binding]; other site 216591003171 active site 216591003172 HMMPfam hit to PF01380, SIS domain, score 3.7e-28 216591003173 HMMPfam hit to PF01380, SIS domain, score 3.6e-29 216591003174 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 1.2e-45 216591003175 PS00443 Glutamine amidotransferases class-II active site. 216591003176 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane]; Region: GlmU; COG1207 216591003177 N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540 216591003178 Substrate binding site; other site 216591003179 Mg++ binding site; other site 216591003180 N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353 216591003181 active site 216591003182 substrate binding site [chemical binding]; other site 216591003183 CoA binding site [chemical binding]; other site 216591003184 PS00101 Hexapeptide-repeat containing-transferases signature. 216591003185 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 0.98 216591003186 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 34 216591003187 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 25 216591003188 PS00101 Hexapeptide-repeat containing-transferases signature. 216591003189 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 3.3 216591003190 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 1.4 216591003191 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 0.2 216591003192 HMMPfam hit to PF00483, Nucleotidyl transferase, score 2e-09 216591003193 HMMPfam hit to PF01128, Uncharacterized protein family UPF000, score 0.00024 216591003194 tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696 216591003195 This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily; Region: Alpha_ANH_like_II; cd01993 216591003196 Ligand Binding Site [chemical binding]; other site 216591003197 HMMPfam hit to PF01171, PP-loop family, score 2.3e-08 216591003198 Dihydroneopterin aldolase; Region: FolB; smart00905 216591003199 active site 216591003200 Probable gene remnant. Similar to the C-terminal regions of Burkholderia ambifaria AMMD hypothetical protein UniProt:Q3FJS9 (EMBL:AAJL01000001) (247 aa) fasta scores: E()=5.1e-56, 92.135% id in 178 aa, and Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) short-chain dehydrogenase/reductase UniProt:Q476S6 (EMBL:CP000090) (277 aa) fasta scores: E()=1.6e-09, 38.679% id in 212 aa 216591003201 Uncharacterized conserved protein [Function unknown]; Region: COG1565 216591003202 HMMPfam hit to PF02636, Uncharacterized ACR, COG1565, score 2.2e-66 216591003203 HMMPfam hit to PF08242, Methyltransferase domain, score 0.0012 216591003204 Protein of unknown function (DUF2905); Region: DUF2905; pfam11146 216591003205 2 probable transmembrane helices predicted for BCAL0616a by TMHMM2.0 at aa 5-23 and 43-60 216591003206 Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167 216591003207 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 216591003208 putative substrate binding site [chemical binding]; other site 216591003209 putative ATP binding site [chemical binding]; other site 216591003210 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 1.9e-37 216591003211 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003212 PS00584 pfkB family of carbohydrate kinases signature 2. 216591003213 Predicted helix-turn-helix motif with score 1038.000, SD 2.72 at aa 175-196, sequence EKMAALADLIKVSDEDLRHLFG 216591003214 PS00583 pfkB family of carbohydrate kinases signature 1. 216591003215 AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249 216591003216 dimerization interface [polypeptide binding]; other site 216591003217 putative active cleft [active] 216591003218 HMMPfam hit to PF07221, N-acylglucosamine 2-epimerase (GlcNAc, score 4.3e-139 216591003219 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591003220 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591003221 DNA binding site [nucleotide binding] 216591003222 domain linker motif; other site 216591003223 Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267 216591003224 ligand binding site [chemical binding]; other site 216591003225 dimerization interface [polypeptide binding]; other site 216591003226 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 9.3e-10 216591003227 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 1.3e-07 216591003228 Predicted helix-turn-helix motif with score 1986.000, SD 5.95 at aa 3-24, sequence TTIRDVARAAEVSIGTVSRALK 216591003229 PS00356 Bacterial regulatory proteins, lacI family signature. 216591003230 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 216591003231 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the GGDEF (DiGuanylate-Cyclase (DGC)) domain. The GGDEF domain has been suggested to be homologous to the adenylyl cyclase catalytic domain and...; Region: CBS_pair_GGDEF_assoc; cd04598 216591003232 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591003233 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591003234 metal binding site [ion binding]; metal-binding site 216591003235 active site 216591003236 I-site; other site 216591003237 HMMPfam hit to PF00990, GGDEF domain, score 1.4e-05 216591003238 HMMPfam hit to PF00571, CBS domain pair, score 0.0011 216591003239 HMMPfam hit to PF00563, EAL domain, score 1.6e-30 216591003240 Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385 216591003241 SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593 216591003242 9 probable transmembrane helices predicted for BCAL0622 by TMHMM2.0 at aa 7-26, 30-52, 65-87, 97-119, 131-153, 163-185, 197-216, 231-253 and 285-307 216591003243 PS00904 Protein prenyltransferases alpha subunit repeat signature. 216591003244 HMMPfam hit to PF01758, Sodium Bile acid symporter family, score 8.8e-05 216591003245 1 probable transmembrane helix predicted for BCAL0623 by TMHMM2.0 at aa 12-31 216591003246 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591003247 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591003248 eyelet of channel; other site 216591003249 trimer interface [polypeptide binding]; other site 216591003250 HMMPfam hit to PF00267, Gram-negative porin, score 0.00044 216591003251 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591003252 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591003253 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591003254 putative effector binding pocket; other site 216591003255 dimerization interface [polypeptide binding]; other site 216591003256 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.6e-11 216591003257 PS00044 Bacterial regulatory proteins, lysR family signature. 216591003258 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.8e-52 216591003259 Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070 216591003260 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 216591003261 FMN binding site [chemical binding]; other site 216591003262 substrate binding site [chemical binding]; other site 216591003263 putative catalytic residue [active] 216591003264 HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 2e-12 216591003265 alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561 216591003266 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.9e-10 216591003267 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591003268 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591003269 dimerization interface [polypeptide binding]; other site 216591003270 putative DNA binding site [nucleotide binding]; other site 216591003271 putative Zn2+ binding site [ion binding]; other site 216591003272 AsnC family; Region: AsnC_trans_reg; pfam01037 216591003273 HMMPfam hit to PF01037, AsnC family, score 9.7e-16 216591003274 PS00519 Bacterial regulatory proteins, asnC family signature. 216591003275 Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950 216591003276 EamA-like transporter family; Region: EamA; cl17759 216591003277 10 probable transmembrane helices predicted for BCAL0629 by TMHMM2.0 at aa 9-27, 37-59, 68-90, 95-117, 124-142, 157-174, 181-203, 213-235, 240-262 and 266-288 216591003278 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.2e-05 216591003279 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.4e-18 216591003280 Protein of unknown function (DUF1289); Region: DUF1289; pfam06945 216591003281 HMMPfam hit to PF06945, Protein of unknown function (DUF1289), score 1.2e-14 216591003282 This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333 216591003283 putative deacylase active site [active] 216591003284 HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associated do, score 5.7e-25 216591003285 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591003286 Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119 216591003287 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938 216591003288 active site 216591003289 catalytic residues [active] 216591003290 metal binding site [ion binding]; metal-binding site 216591003291 HMMPfam hit to PF00682, HMGL-like, score 3.4e-74 216591003292 PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 216591003293 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003294 bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469 216591003295 Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164 216591003296 putative ligand binding site [chemical binding]; other site 216591003297 NAD binding site [chemical binding]; other site 216591003298 dimerization interface [polypeptide binding]; other site 216591003299 catalytic site [active] 216591003300 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydro, score 8.5e-48 216591003301 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 0.0006 216591003302 Serine hydrolase; Region: Ser_hydrolase; pfam06821 216591003303 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591003304 HMMPfam hit to PF06821, Alpha/Beta hydrolase family of unknown funct, score 1.5e-65 216591003305 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003306 4-hydroxybenzoyl-CoA reductase, gamma subunit; Region: 4hydroxCoAred; TIGR03193 216591003307 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591003308 catalytic loop [active] 216591003309 iron binding site [ion binding]; other site 216591003310 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 216591003311 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 1.2e-09 216591003312 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591003313 HMMPfam hit to PF01799, [2Fe-2S] binding domain, score 1.6e-36 216591003314 PS00070 Aldehyde dehydrogenases cysteine active site. 216591003315 FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941 216591003316 CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092 216591003317 HMMPfam hit to PF00941, FAD binding domain in molybdopterin deh, score 2.3e-88 216591003318 HMMPfam hit to PF03450, CO dehydrogenase flavoprotein C-termina, score 0.00013 216591003319 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 216591003320 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 216591003321 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591003322 HMMPfam hit to PF01315, Aldehyde oxidase and xanthine dehydroge, score 8.8e-20 216591003323 HMMPfam hit to PF02738, Aldehyde oxidase and xanthine dehydroge, score 1.1e-74 216591003324 Predicted helix-turn-helix motif with score 1009.000, SD 2.62 at aa 211-232, sequence GTSAAVAAVFGIAPEQVRVISP 216591003325 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003326 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591003327 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591003328 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591003329 dimerization interface [polypeptide binding]; other site 216591003330 substrate binding pocket [chemical binding]; other site 216591003331 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.2e-36 216591003332 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.3e-17 216591003333 PS00044 Bacterial regulatory proteins, lysR family signature. 216591003334 Predicted helix-turn-helix motif with score 1624.000, SD 4.72 at aa 22-43, sequence QSFTRAADELALTQGAVSQHIR 216591003335 GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057 216591003336 C-terminal domain interface [polypeptide binding]; other site 216591003337 GSH binding site (G-site) [chemical binding]; other site 216591003338 dimer interface [polypeptide binding]; other site 216591003339 C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188 216591003340 dimer interface [polypeptide binding]; other site 216591003341 substrate binding pocket (H-site) [chemical binding]; other site 216591003342 N-terminal domain interface [polypeptide binding]; other site 216591003343 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 1e-11 216591003344 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591003345 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591003346 12 probable transmembrane helices predicted for BCAL0640 by TMHMM2.0 at aa 23-45, 60-82, 91-113, 123-142, 163-180, 185-207, 242-264, 274-296, 309-331, 336-358, 365-387 and 402-421 216591003347 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.1e-50 216591003348 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591003349 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591003350 dimerization interface [polypeptide binding]; other site 216591003351 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 7.2e-14 216591003352 Predicted helix-turn-helix motif with score 1107.000, SD 2.96 at aa 44-65, sequence GSFAKAADRVARSSSAVSAQIR 216591003353 PS00044 Bacterial regulatory proteins, lysR family signature. 216591003354 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-26 216591003355 PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872 216591003356 putative active site [active] 216591003357 HMMPfam hit to PF01850, PIN domain, score 2.7e-10 216591003358 Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329 216591003359 Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950 216591003360 dimer interface [polypeptide binding]; other site 216591003361 active site 216591003362 catalytic residue [active] 216591003363 HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 5.9e-56 216591003364 PS00666 Dihydrodipicolinate synthetase signature 2. 216591003365 ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: Sbp; COG1613 216591003366 Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531 216591003367 PS00782 Transcription factor TFIIB repeat signature. 216591003368 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 3.8e-06 216591003369 Inward rectifier potassium channel; Region: IRK; pfam01007 216591003370 HMMPfam hit to PF01007, Inward rectifier potassium channel, score 7e-17 216591003371 PS00041 Bacterial regulatory proteins, araC family signature. 216591003372 3 probable transmembrane helices predicted for BCAL0646 by TMHMM2.0 at aa 61-83, 93-112 and 124-146 216591003373 HMMPfam hit to PF07885, Ion channel, score 3e-14 216591003374 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591003375 GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046 216591003376 putative C-terminal domain interface [polypeptide binding]; other site 216591003377 putative GSH binding site (G-site) [chemical binding]; other site 216591003378 putative dimer interface [polypeptide binding]; other site 216591003379 C-terminal, alpha helical domain of an unknown subfamily 8 of Glutathione S-transferases; Region: GST_C_8; cd03207 216591003380 dimer interface [polypeptide binding]; other site 216591003381 N-terminal domain interface [polypeptide binding]; other site 216591003382 putative substrate binding pocket (H-site) [chemical binding]; other site 216591003383 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 3.5e-14 216591003384 CDS contains a frameshift after codon 78. Similar to Rhizobium leguminosarum bv. viciae nodulation protein L NodL UniProt:P08632 (EMBL:RLNODLGEE) (190 aa) fasta scores: E()=1.1e-16, 40.881% id in 159 aa 216591003385 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1.2 216591003386 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.0018 216591003387 PS00101 Hexapeptide-repeat containing-transferases signature. 216591003388 2-oxoacid ferredoxin oxidoreductase; Provisional; Region: PRK13030 216591003389 Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034 216591003390 dimer interface [polypeptide binding]; other site 216591003391 PYR/PP interface [polypeptide binding]; other site 216591003392 TPP binding site [chemical binding]; other site 216591003393 substrate binding site [chemical binding]; other site 216591003394 Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as...; Region: TPP_IOR_alpha; cd02008 216591003395 TPP-binding site; other site 216591003396 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014 216591003397 HMMPfam hit to PF01558, Pyruvate ferredoxin/flavodoxin oxidoreductas, score 1.5e-05 216591003398 PS00017 ATP/GTP-binding site motif A (P-loop). 216591003399 Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831 216591003400 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482 216591003401 Predicted helix-turn-helix motif with score 1002.000, SD 2.60 at aa 565-586, sequence ETLTKLIREIDLSETALSTRKK 216591003402 HMMPfam hit to PF00999, Sodium/hydrogen exchanger family, score 4.8e-62 216591003403 13 probable transmembrane helices predicted for BCAL0651 by TMHMM2.0 at aa 24-46, 53-75, 90-107, 120-142, 148-170, 191-213, 218-240, 253-270, 275-294, 315-337, 350-372, 395-417 and 432-454 216591003404 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 216591003405 HMMPfam hit to PF00563, EAL domain, score 1.2e-35 216591003406 4 probable transmembrane helices predicted for BCAL0653 by TMHMM2.0 at aa 5-27, 42-64, 76-93 and 98-115 216591003407 4 probable transmembrane helices predicted for BCAL0654 by TMHMM2.0 at aa 7-29, 39-61, 68-90 and 110-132 216591003408 CutC family; Region: CutC; cl01218 216591003409 HMMPfam hit to PF03932, CutC family, score 6.7e-47 216591003410 Suppressor of fused protein (SUFU); Region: SUFU; pfam05076 216591003411 Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456 216591003412 12 probable transmembrane helices predicted for BCAL0657 by TMHMM2.0 at aa 34-56, 61-83, 95-117, 137-159, 166-188, 198-220, 241-263, 273-295, 327-346, 350-372, 393-412 and 417-439 216591003413 Allophanate hydrolase subunit 2; Region: AHS2; smart00797 216591003414 HMMPfam hit to PF02626, Allophanate hydrolase subunit, score 1.4e-74 216591003415 Allophanate hydrolase subunit 1; Region: AHS1; smart00796 216591003416 Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049 216591003417 HMMPfam hit to PF02682, Allophanate hydrolase subunit, score 5.4e-07 216591003418 acetyl-CoA carboxylase biotin carboxylase subunit; Provisional; Region: PRK12833 216591003419 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 216591003420 ATP-grasp domain; Region: ATP-grasp_4; cl17255 216591003421 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 216591003422 HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain, score 2.3e-55 216591003423 HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 8e-102 216591003424 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 216591003425 HMMPfam hit to PF02222, ATP-grasp domain, score 0.003 216591003426 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 216591003427 HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 5.9e-40 216591003428 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 216591003429 carboxyltransferase (CT) interaction site; other site 216591003430 biotinylation site [posttranslational modification]; other site 216591003431 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 1.5e-21 216591003432 hypothetical protein; Provisional; Region: PRK12569 216591003433 HMMPfam hit to PF03746, LamB/YcsF family, score 2e-125 216591003434 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591003435 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591003436 The C-terminal substrate-binding domain of putative LysR-type transcriptional regulator PAO1-like, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_PAO1_like; cd08412 216591003437 putative substrate binding pocket [chemical binding]; other site 216591003438 dimerization interface [polypeptide binding]; other site 216591003439 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.9e-19 216591003440 Predicted helix-turn-helix motif with score 1384.000, SD 3.90 at aa 18-39, sequence GQISQAAIQLTISQSAVTSAIK 216591003441 PS00044 Bacterial regulatory proteins, lysR family signature. 216591003442 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.4e-45 216591003443 biotin synthase; Region: bioB; TIGR00433 216591003444 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591003445 FeS/SAM binding site; other site 216591003446 Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876 216591003447 HMMPfam hit to PF06968, Biotin and Thiamin Synthesis associated d, score 9.9e-45 216591003448 HMMPfam hit to PF04055, Radical SAM superfamily, score 3e-26 216591003449 dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090 216591003450 AAA domain; Region: AAA_26; pfam13500 216591003451 8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958 216591003452 pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825 216591003453 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591003454 catalytic residue [active] 216591003455 HMMPfam hit to PF00155, Aminotransferase class I and II, score 2.4e-68 216591003456 HMMPfam hit to PF00202, Aminotransferase class-III, score 0.27 216591003457 adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK06943 216591003458 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591003459 inhibitor-cofactor binding pocket; inhibition site 216591003460 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591003461 catalytic residue [active] 216591003462 HMMPfam hit to PF00202, Aminotransferase class-III, score 9.5e-117 216591003463 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591003464 PS00436 Peroxidases active site signature. 216591003465 Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412 216591003466 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 216591003467 hypothetical protein; Provisional; Region: PRK01842 216591003468 C factor cell-cell signaling protein; Provisional; Region: PRK09009 216591003469 carbonyl reductase sniffer-like, classical (c) SDRs; Region: carb_red_sniffer_like_SDR_c; cd05325 216591003470 NADP binding site [chemical binding]; other site 216591003471 homodimer interface [polypeptide binding]; other site 216591003472 active site 216591003473 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.6e-07 216591003474 Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883 216591003475 active site clefts [active] 216591003476 zinc binding site [ion binding]; other site 216591003477 dimer interface [polypeptide binding]; other site 216591003478 HMMPfam hit to PF00484, Carbonic anhydrase, score 5.1e-36 216591003479 PS00704 Prokaryotic-type carbonic anhydrases signature 1. 216591003480 bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946 216591003481 Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579 216591003482 HMMPfam hit to PF06315, Isocitrate dehydrogenase kinase/phosphatase, score 0 216591003483 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 216591003484 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 3.4e-23 216591003485 ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488 216591003486 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591003487 Walker A/P-loop; other site 216591003488 ATP binding site [chemical binding]; other site 216591003489 ABC transporter signature motif; other site 216591003490 Walker B; other site 216591003491 D-loop; other site 216591003492 H-loop/switch region; other site 216591003493 ABC transporter; Region: ABC_tran_2; pfam12848 216591003494 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 216591003495 HMMPfam hit to PF00005, ABC transporter, score 3.7e-33 216591003496 PS00017 ATP/GTP-binding site motif A (P-loop). 216591003497 HMMPfam hit to PF00005, ABC transporter, score 1.9e-32 216591003498 PS00211 ABC transporters family signature. 216591003499 PS00017 ATP/GTP-binding site motif A (P-loop). 216591003500 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 216591003501 The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493 216591003502 peptide binding site [polypeptide binding]; other site 216591003503 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 9.1e-85 216591003504 short chain dehydrogenase; Provisional; Region: PRK07024 216591003505 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591003506 NAD(P) binding site [chemical binding]; other site 216591003507 active site 216591003508 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.5e-21 216591003509 PS00061 Short-chain dehydrogenases/reductases family signature. 216591003510 DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019 216591003511 DSBA-like thioredoxin domain; Region: DSBA; pfam01323 216591003512 catalytic residues [active] 216591003513 hinge region; other site 216591003514 alpha helical domain; other site 216591003515 HMMPfam hit to PF01323, DSBA-like thioredoxin domain, score 7.3e-12 216591003516 PS00194 Thioredoxin family active site. 216591003517 Sporulation related domain; Region: SPOR; pfam05036 216591003518 HMMPfam hit to PF05036, Sporulation related domain, score 1.6e-20 216591003519 1 probable transmembrane helix predicted for BCAL0678 by TMHMM2.0 at aa 2-19 216591003520 arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611 216591003521 Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016 216591003522 catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671 216591003523 active site 216591003524 HIGH motif; other site 216591003525 KMSK motif region; other site 216591003526 Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956 216591003527 tRNA binding surface [nucleotide binding]; other site 216591003528 anticodon binding site; other site 216591003529 HMMPfam hit to PF05746, DALR anticodon binding domain, score 4.8e-44 216591003530 HMMPfam hit to PF00750, tRNA synthetases class I (R), score 1.5e-67 216591003531 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591003532 HMMPfam hit to PF03485, Arginyl tRNA synthetase N terminal do, score 2e-23 216591003533 Domain of unknown function (DUF1840); Region: DUF1840; pfam08895 216591003534 Methionine synthase I, cobalamin-binding domain [Amino acid transport and metabolism]; Region: MetH; COG1410 216591003535 MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH). Cobalamin-dependent...; Region: MeTr; cd00740 216591003536 substrate binding pocket [chemical binding]; other site 216591003537 B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069 216591003538 B12 binding site [chemical binding]; other site 216591003539 cobalt ligand [ion binding]; other site 216591003540 Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965 216591003541 HMMPfam hit to PF02965, Vitamin B12 dependent methionine syntha, score 2.3e-65 216591003542 HMMPfam hit to PF02310, B12 binding domain, score 2e-22 216591003543 HMMPfam hit to PF02607, B12 binding domain, score 3.9e-42 216591003544 HMMPfam hit to PF00809, Pterin binding enzyme, score 3.2e-72 216591003545 Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646 216591003546 Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574 216591003547 HMMPfam hit to PF02574, Homocysteine S-methyltransferase, score 1e-144 216591003548 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003549 Protein of unknown function (DUF3567); Region: DUF3567; pfam12091 216591003550 Protein of unknown function (DUF3108); Region: DUF3108; pfam11306 216591003551 1 probable transmembrane helix predicted for BCAL0684 by TMHMM2.0 at aa 35-57 216591003552 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 216591003553 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591003554 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 0.002 216591003555 PS00043 Bacterial regulatory proteins, gntR family signature. 216591003556 Predicted helix-turn-helix motif with score 1287.000, SD 3.57 at aa 52-73, sequence MMLRDLAQRAGMSPAKAHRYLV 216591003557 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 216591003558 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 216591003559 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 1.8e-07 216591003560 Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024 216591003561 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591003562 substrate binding site [chemical binding]; other site 216591003563 oxyanion hole (OAH) forming residues; other site 216591003564 trimer interface [polypeptide binding]; other site 216591003565 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 6.6e-21 216591003566 PS00166 Enoyl-CoA hydratase/isomerase signature. 216591003567 Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209 216591003568 active site 216591003569 nucleophile elbow; other site 216591003570 HMMPfam hit to PF01734, Patatin-like phospholipase, score 2.5e-11 216591003571 Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264 216591003572 dinuclear metal binding motif [ion binding]; other site 216591003573 rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199 216591003574 Cytidylyltransferase; Region: CTP_transf_2; pfam01467 216591003575 active site 216591003576 HIGH motif; other site 216591003577 nucleotide binding site [chemical binding]; other site 216591003578 HMMPfam hit to PF01467, Cytidylyltransferase, score 8.4e-23 216591003579 1 probable transmembrane helix predicted for BCAL0692 by TMHMM2.0 at aa 2-24 216591003580 pantothenate kinase; Reviewed; Region: PRK13328 216591003581 HMMPfam hit to PF03309, Bordetella pertussis Bvg accessory fac, score 4.4e-12 216591003582 biotin--protein ligase; Provisional; Region: PRK06955 216591003583 Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057 216591003584 Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237 216591003585 HMMPfam hit to PF02237, Biotin protein ligase C terminal domain, score 7.2e-09 216591003586 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003587 HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase famil, score 3.5e-07 216591003588 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 216591003589 HMMPfam hit to PF08238, Sel1 repeat, score 6.3e-06 216591003590 HMMPfam hit to PF08238, Sel1 repeat, score 7.6e-06 216591003591 HMMPfam hit to PF08238, Sel1 repeat, score 1e-05 216591003592 1 probable transmembrane helix predicted for BCAL0695 by TMHMM2.0 at aa 21-43 216591003593 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420 216591003594 Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410 216591003595 active site 216591003596 metal binding site [ion binding]; metal-binding site 216591003597 5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872 216591003598 HMMPfam hit to PF02872, 5'-nucleotidase, C-terminal domain, score 1.5e-39 216591003599 Predicted helix-turn-helix motif with score 985.000, SD 2.54 at aa 544-565, sequence FTSADLAYEIDVTQPVGSRIRN 216591003600 PS00017 ATP/GTP-binding site motif A (P-loop). 216591003601 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 4.1e-11 216591003602 PS00017 ATP/GTP-binding site motif A (P-loop). 216591003603 PS00786 5'-nucleotidase signature 2. 216591003604 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591003605 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003606 ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767 216591003607 Permease; Region: Permease; pfam02405 216591003608 HMMPfam hit to PF02405, Domain of unknown function DUF140, score 2e-55 216591003609 5 probable transmembrane helices predicted for BCAL0697 by TMHMM2.0 at aa 163-185, 198-220, 269-291, 304-326 and 346-368 216591003610 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003611 ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127 216591003612 ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261 216591003613 Walker A/P-loop; other site 216591003614 ATP binding site [chemical binding]; other site 216591003615 Q-loop/lid; other site 216591003616 ABC transporter signature motif; other site 216591003617 Walker B; other site 216591003618 D-loop; other site 216591003619 H-loop/switch region; other site 216591003620 HMMPfam hit to PF00005, ABC transporter, score 1.4e-54 216591003621 PS00017 ATP/GTP-binding site motif A (P-loop). 216591003622 ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463 216591003623 mce related protein; Region: MCE; pfam02470 216591003624 1 probable transmembrane helix predicted for BCAL0699 by TMHMM2.0 at aa 7-29 216591003625 HMMPfam hit to PF02470, mce related protein, score 1.9e-17 216591003626 Protein of unknown function (DUF330); Region: DUF330; pfam03886 216591003627 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003628 Predicted integral membrane protein [Function unknown]; Region: COG5652 216591003629 10 probable transmembrane helices predicted for BCAL0701 by TMHMM2.0 at aa 17-39, 54-76, 81-103, 118-140, 160-182, 224-246, 253-275, 280-302, 309-331 and 346-368 216591003630 Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980 216591003631 dimer interface [polypeptide binding]; other site 216591003632 [2Fe-2S] cluster binding site [ion binding]; other site 216591003633 Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945 216591003634 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686 216591003635 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872 216591003636 Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936 216591003637 HMMPfam hit to PF00144, Beta-lactamase, score 0.00033 216591003638 HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase, score 6.4e-97 216591003639 HMMPfam hit to PF07943, Penicillin-binding protein 5, C-termin, score 9.7e-29 216591003640 D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558 216591003641 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115 216591003642 homodimer interface [polypeptide binding]; other site 216591003643 substrate-cofactor binding pocket; other site 216591003644 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591003645 catalytic residue [active] 216591003646 HMMPfam hit to PF01063, Aminotransferase class IV, score 1.6e-59 216591003647 hypothetical protein; Provisional; Region: PRK02047 216591003648 HMMPfam hit to PF04359, Protein of unknown function (DUF493), score 1.5e-35 216591003649 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591003650 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591003651 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591003652 dimerization interface [polypeptide binding]; other site 216591003653 substrate binding pocket [chemical binding]; other site 216591003654 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.9e-42 216591003655 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 7.1e-21 216591003656 PS00044 Bacterial regulatory proteins, lysR family signature. 216591003657 Predicted helix-turn-helix motif with score 1399.000, SD 3.95 at aa 22-43, sequence ENFSRAADELFVTHGAVSHQVR 216591003658 Protein of unknown function (DUF2917); Region: DUF2917; pfam11142 216591003659 lipoate-protein ligase B; Provisional; Region: PRK14343 216591003660 HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase famil, score 1.6e-12 216591003661 PS00141 Eukaryotic and viral aspartyl proteases active site. 216591003662 PS01313 Lipoate-protein ligase B signature. 216591003663 lipoyl synthase; Provisional; Region: PRK05481 216591003664 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591003665 FeS/SAM binding site; other site 216591003666 HMMPfam hit to PF04055, Radical SAM superfamily, score 2.8e-25 216591003667 ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521 216591003668 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591003669 substrate binding pocket [chemical binding]; other site 216591003670 membrane-bound complex binding site; other site 216591003671 hinge residues; other site 216591003672 HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 2.7e-06 216591003673 taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248 216591003674 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 216591003675 Walker A/P-loop; other site 216591003676 ATP binding site [chemical binding]; other site 216591003677 Q-loop/lid; other site 216591003678 ABC transporter signature motif; other site 216591003679 Walker B; other site 216591003680 D-loop; other site 216591003681 H-loop/switch region; other site 216591003682 HMMPfam hit to PF00005, ABC transporter, score 5.7e-57 216591003683 PS00017 ATP/GTP-binding site motif A (P-loop). 216591003684 PS00211 ABC transporters family signature. 216591003685 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591003686 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591003687 dimer interface [polypeptide binding]; other site 216591003688 conserved gate region; other site 216591003689 putative PBP binding loops; other site 216591003690 ABC-ATPase subunit interface; other site 216591003691 6 probable transmembrane helices predicted for BCAL0713 by TMHMM2.0 at aa 45-64, 107-129, 141-163, 168-187, 231-253 and 263-285 216591003692 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.2e-30 216591003693 Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405 216591003694 Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019 216591003695 HMMPfam hit to PF01019, Gamma-glutamyltranspeptidase, score 8.4e-187 216591003696 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591003697 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591003698 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591003699 putative effector binding pocket; other site 216591003700 dimerization interface [polypeptide binding]; other site 216591003701 HMMPfam hit to PF03466, LysR substrate binding domain, score 8.5e-41 216591003702 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.2e-16 216591003703 PS00044 Bacterial regulatory proteins, lysR family signature. 216591003704 Predicted helix-turn-helix motif with score 1750.000, SD 5.15 at aa 16-37, sequence GNLSKAAQRLKMSRANVSYRLN 216591003705 multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154 216591003706 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591003707 substrate binding site [chemical binding]; other site 216591003708 oxyanion hole (OAH) forming residues; other site 216591003709 trimer interface [polypeptide binding]; other site 216591003710 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 216591003711 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 216591003712 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 216591003713 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 7.8e-55 216591003714 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD binding, score 5.5e-80 216591003715 PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 216591003716 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 1.9e-32 216591003717 pimeloyl-CoA dehydrogenase, large subunit; Region: pimC_large; TIGR03204 216591003718 Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26; Region: ACAD_fadE6_17_26; cd01152 216591003719 FAD binding site [chemical binding]; other site 216591003720 substrate binding site [chemical binding]; other site 216591003721 catalytic base [active] 216591003722 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 2.4e-24 216591003723 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 2.7e-27 216591003724 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591003725 pimeloyl-CoA dehydrogenase, small subunit; Region: pimD_small; TIGR03203 216591003726 Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771 216591003727 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 216591003728 active site 216591003729 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 5.6e-06 216591003730 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 1.4e-16 216591003731 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 0.0021 216591003732 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591003733 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591003734 HMMPfam hit to PF02515, CoA-transferase family III, score 2.6e-65 216591003735 PS00213 Lipocalin signature. 216591003736 Protein of unknown function, DUF485; Region: DUF485; pfam04341 216591003737 HMMPfam hit to PF04341, Protein of unknown function, DUF485, score 8.4e-24 216591003738 2 probable transmembrane helices predicted for BCAL0720 by TMHMM2.0 at aa 25-47 and 62-84 216591003739 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003740 Predicted symporter [General function prediction only]; Region: DhlC; COG4147 216591003741 Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480 216591003742 Na binding site [ion binding]; other site 216591003743 14 probable transmembrane helices predicted for BCAL0721 by TMHMM2.0 at aa 7-26, 36-58, 79-101, 106-128, 148-170, 180-202, 215-237, 267-289, 301-323, 373-395, 416-438, 443-465, 472-491 and 506-528 216591003744 HMMPfam hit to PF00474, Sodium:solute symporter family, score 1.2e-132 216591003745 C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663 216591003746 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 216591003747 HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 1.5e-172 216591003748 8 probable transmembrane helices predicted for BCAL0722 by TMHMM2.0 at aa 7-25, 40-57, 70-92, 137-159, 179-201, 216-238, 307-329 and 344-366 216591003749 PS00713 Sodium:dicarboxylate symporter family signature 1. 216591003750 PS00714 Sodium:dicarboxylate symporter family signature 2. 216591003751 Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms]; Region: COG4191 216591003752 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591003753 dimer interface [polypeptide binding]; other site 216591003754 phosphorylation site [posttranslational modification] 216591003755 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591003756 ATP binding site [chemical binding]; other site 216591003757 G-X-G motif; other site 216591003758 2 probable transmembrane helices predicted for BCAL0723 by TMHMM2.0 at aa 43-65 and 331-349 216591003759 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003760 PS00210 Arthropod hemocyanins / insect LSPs signature 2. 216591003761 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.4e-07 216591003762 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.1e-31 216591003763 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 216591003764 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591003765 active site 216591003766 phosphorylation site [posttranslational modification] 216591003767 intermolecular recognition site; other site 216591003768 dimerization interface [polypeptide binding]; other site 216591003769 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591003770 Walker A motif; other site 216591003771 ATP binding site [chemical binding]; other site 216591003772 Walker B motif; other site 216591003773 arginine finger; other site 216591003774 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591003775 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.8e-32 216591003776 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 1.3e-139 216591003777 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591003778 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591003779 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591003780 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 3.8e-11 216591003781 TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966 216591003782 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591003783 catalytic residues [active] 216591003784 HMMPfam hit to PF08534, Redoxin, score 9.8e-37 216591003785 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003786 1 probable transmembrane helix predicted for BCAL0725 by TMHMM2.0 at aa 12-34 216591003787 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003788 Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606 216591003789 Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541 216591003790 Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078 216591003791 Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335 216591003792 HMMPfam hit to PF01078, Magnesium chelatase, subunit ChlI, score 5.3e-143 216591003793 HMMPfam hit to PF07728, ATPase family associated with various ce, score 8.3e-05 216591003794 PS00017 ATP/GTP-binding site motif A (P-loop). 216591003795 Membrane fusogenic activity; Region: BMFP; pfam04380 216591003796 HMMPfam hit to PF04380, Protein of unknown function (DUF526), score 8.3e-27 216591003797 Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347 216591003798 Nitrogen regulatory protein P-II; Region: P-II; smart00938 216591003799 HMMPfam hit to PF00543, Nitrogen regulatory protein P-II, score 1.9e-70 216591003800 PS00496 P-II protein urydylation site. 216591003801 PS00638 P-II protein C-terminal region signature. 216591003802 Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004 216591003803 HMMPfam hit to PF00909, Ammonium Transporter Family, score 1.6e-156 216591003804 11 probable transmembrane helices predicted for BCAL0730 by TMHMM2.0 at aa 98-120, 127-149, 195-217, 222-244, 259-281, 294-313, 328-350, 355-374, 378-400, 413-432 and 442-464 216591003805 PS01219 Ammonium transporters signature. 216591003806 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003807 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003808 glutamate--cysteine ligase, T. ferrooxidans family; Region: gshA_ferroox; TIGR02049 216591003809 Glutamate-cysteine ligase; Region: GshA; pfam08886 216591003810 glutathione synthetase; Provisional; Region: PRK05246 216591003811 Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951 216591003812 Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955 216591003813 HMMPfam hit to PF02951, Prokaryotic glutathione synthetase, N-termi, score 1.5e-24 216591003814 HMMPfam hit to PF08443, RimK-like ATP-grasp domain, score 5.6e-05 216591003815 HMMPfam hit to PF02955, Prokaryotic glutathione synthetase, ATP-gra, score 7.4e-118 216591003816 PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006 216591003817 active pocket/dimerization site; other site 216591003818 active site 216591003819 phosphorylation site [posttranslational modification] 216591003820 HMMPfam hit to PF03610, PTS system fructose IIA component, score 4.7e-12 216591003821 Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367 216591003822 dimerization domain swap beta strand [polypeptide binding]; other site 216591003823 regulatory protein interface [polypeptide binding]; other site 216591003824 active site 216591003825 regulatory phosphorylation site [posttranslational modification]; other site 216591003826 HMMPfam hit to PF00381, PTS HPr component phosphorylation site, score 1.7e-47 216591003827 PS00369 PTS HPR component histidine phosphorylation site signature. 216591003828 PS00589 PTS HPR component serine phosphorylation site signature. 216591003829 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080 216591003830 PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524 216591003831 PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391 216591003832 PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 216591003833 HMMPfam hit to PF05524, PEP-utilising enzyme, N-terminal, score 2.7e-45 216591003834 HMMPfam hit to PF00391, PEP-utilising enzyme, mobile domain, score 1.1e-28 216591003835 PS00370 PEP-utilizing enzymes phosphorylation site signature. 216591003836 HMMPfam hit to PF02896, PEP-utilising enzyme, TIM barrel doma, score 2e-149 216591003837 PS00742 PEP-utilizing enzymes signature 2. 216591003838 molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690 216591003839 ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757 216591003840 ATP binding site [chemical binding]; other site 216591003841 substrate interface [chemical binding]; other site 216591003842 HMMPfam hit to PF05237, MoeZ/MoeB domain, score 8.8e-35 216591003843 HMMPfam hit to PF00899, ThiF family, score 5.6e-64 216591003844 C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526 216591003845 C-terminal peptidase (prc); Region: prc; TIGR00225 216591003846 PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988 216591003847 protein binding site [polypeptide binding]; other site 216591003848 C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560 216591003849 Catalytic dyad [active] 216591003850 HMMPfam hit to PF03572, Peptidase family S41, score 1.3e-78 216591003851 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 2.7e-15 216591003852 1 probable transmembrane helix predicted for BCAL0738 by TMHMM2.0 at aa 7-29 216591003853 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 216591003854 catalytic core [active] 216591003855 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 216591003856 HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 3.4e-43 216591003857 PS00175 Phosphoglycerate mutase family phosphohistidine signature. 216591003858 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 216591003859 active site residue [active] 216591003860 1 probable transmembrane helix predicted for BCAL0740 by TMHMM2.0 at aa 7-29 216591003861 HMMPfam hit to PF00581, Rhodanese-like domain, score 8.9e-13 216591003862 Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418 216591003863 GSH binding site [chemical binding]; other site 216591003864 catalytic residues [active] 216591003865 HMMPfam hit to PF00462, Glutaredoxin, score 2.2e-23 216591003866 preprotein translocase subunit SecB; Validated; Region: PRK05751 216591003867 SecA binding site; other site 216591003868 Preprotein binding site; other site 216591003869 HMMPfam hit to PF02556, Preprotein translocase subunit SecB, score 1.3e-37 216591003870 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094 216591003871 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210 216591003872 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479 216591003873 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 1.6e-43 216591003874 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003875 HMMPfam hit to PF07479, NAD-dependent glycerol-3-phosphate deh, score 7.6e-63 216591003876 PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 216591003877 Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908 216591003878 putative ADP-ribose binding site [chemical binding]; other site 216591003879 putative active site [active] 216591003880 HMMPfam hit to PF01661, Appr-1-p processing enzyme family, score 7.4e-62 216591003881 Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219 216591003882 HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 1.8e-39 216591003883 Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040 216591003884 PS00217 Sugar transport proteins signature 2. 216591003885 biotin biosynthesis protein BioC; Region: BioC; TIGR02072 216591003886 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591003887 S-adenosylmethionine binding site [chemical binding]; other site 216591003888 PS00136 Serine proteases, subtilase family, aspartic acid active site. 216591003889 HMMPfam hit to PF08241, Methyltransferase domain, score 1.2e-22 216591003890 HMMPfam hit to PF08242, Methyltransferase domain, score 6.4e-14 216591003891 Integral membrane protein (DUF2244); Region: DUF2244; pfam10003 216591003892 2 probable transmembrane helices predicted for BCAL0748 by TMHMM2.0 at aa 33-52 and 56-78 216591003893 Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790 216591003894 cytochrome c oxidase subunit II; Provisional; Region: COX2; MTH00140 216591003895 Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116 216591003896 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591003897 Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442 216591003898 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591003899 ligand binding site [chemical binding]; other site 216591003900 3 probable transmembrane helices predicted for BCAL0749 by TMHMM2.0 at aa 7-26, 56-78 and 99-121 216591003901 HMMPfam hit to PF02790, Cytochrome C oxidase subunit II, transmem, score 7.1e-13 216591003902 HMMPfam hit to PF00116, Cytochrome C oxidase subunit II, periplas, score 8.5e-36 216591003903 PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 216591003904 HMMPfam hit to PF00034, Cytochrome c, score 0.00012 216591003905 PS00190 Cytochrome c family heme-binding site signature. 216591003906 HMMPfam hit to PF00691, OmpA family, score 4.4e-11 216591003907 Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843 216591003908 Cytochrome C oxidase subunit I. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_I; cd01663 216591003909 Subunit I/III interface [polypeptide binding]; other site 216591003910 D-pathway; other site 216591003911 Subunit I/VIIc interface [polypeptide binding]; other site 216591003912 Subunit I/IV interface [polypeptide binding]; other site 216591003913 Subunit I/II interface [polypeptide binding]; other site 216591003914 Low-spin heme (heme a) binding site [chemical binding]; other site 216591003915 Subunit I/VIIa interface [polypeptide binding]; other site 216591003916 Subunit I/VIa interface [polypeptide binding]; other site 216591003917 Dimer interface; other site 216591003918 Putative water exit pathway; other site 216591003919 Binuclear center (heme a3/CuB) [ion binding]; other site 216591003920 K-pathway; other site 216591003921 Subunit I/Vb interface [polypeptide binding]; other site 216591003922 Putative proton exit pathway; other site 216591003923 Subunit I/VIb interface; other site 216591003924 Subunit I/VIc interface [polypeptide binding]; other site 216591003925 Electron transfer pathway; other site 216591003926 Subunit I/VIIIb interface [polypeptide binding]; other site 216591003927 Subunit I/VIIb interface [polypeptide binding]; other site 216591003928 HMMPfam hit to PF00115, Cytochrome C and Quinol oxidase polypeptide, score 1.4e-254 216591003929 12 probable transmembrane helices predicted for BCAL0750 by TMHMM2.0 at aa 37-59, 79-101, 121-143, 166-188, 208-230, 255-277, 284-306, 321-343, 356-378, 393-415, 428-450 and 470-492 216591003930 PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 216591003931 1 probable transmembrane helix predicted for BCAL0751 by TMHMM2.0 at aa 21-43 216591003932 cytochrome C oxidase assembly protein; Provisional; Region: PRK05089 216591003933 1 probable transmembrane helix predicted for BCAL0752 by TMHMM2.0 at aa 21-43 216591003934 HMMPfam hit to PF04442, Cytochrome c oxidase assembly protein Cta, score 1.1e-45 216591003935 Protein of unknown function (DUF2970); Region: DUF2970; pfam11174 216591003936 1 probable transmembrane helix predicted for BCAL0753 by TMHMM2.0 at aa 43-65 216591003937 Cytochrome c oxidase subunit III. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_III; cd01665 216591003938 Subunit III/VIIa interface [polypeptide binding]; other site 216591003939 Phospholipid binding site [chemical binding]; other site 216591003940 Subunit I/III interface [polypeptide binding]; other site 216591003941 Subunit III/VIb interface [polypeptide binding]; other site 216591003942 Subunit III/VIa interface; other site 216591003943 Subunit III/Vb interface [polypeptide binding]; other site 216591003944 HMMPfam hit to PF00510, Cytochrome c oxidase subunit III, score 1.4e-57 216591003945 6 probable transmembrane helices predicted for BCAL0754 by TMHMM2.0 at aa 20-37, 42-64, 84-106, 181-203, 223-245 and 265-284 216591003946 Protein of unknown function (DUF2909); Region: DUF2909; pfam11137 216591003947 2 probable transmembrane helices predicted for BCAL0755 by TMHMM2.0 at aa 5-24 and 37-59 216591003948 SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662 216591003949 3 probable transmembrane helices predicted for BCAL0756 by TMHMM2.0 at aa 5-24, 89-111 and 207-226 216591003950 Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388 216591003951 1 probable transmembrane helix predicted for BCAL0757 by TMHMM2.0 at aa 23-45 216591003952 Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612 216591003953 Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628 216591003954 10 probable transmembrane helices predicted for BCAL0758 by TMHMM2.0 at aa 2-24, 34-51, 64-86, 101-123, 136-158, 162-184, 205-227, 270-292, 304-326 and 331-353 216591003955 HMMPfam hit to PF02628, Cytochrome oxidase assembly protein, score 2.3e-08 216591003956 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003957 protoheme IX farnesyltransferase; Provisional; Region: PRK04375 216591003958 UbiA prenyltransferase family; Region: UbiA; pfam01040 216591003959 HMMPfam hit to PF01040, UbiA prenyltransferase family, score 5.8e-72 216591003960 9 probable transmembrane helices predicted for BCAL0759 by TMHMM2.0 at aa 27-44, 48-70, 91-113, 118-138, 145-167, 171-193, 214-236, 240-259 and 272-294 216591003961 PS00943 UbiA prenyltransferase family signature. 216591003962 SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968 216591003963 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591003964 Cu(I) binding site [ion binding]; other site 216591003965 HMMPfam hit to PF02630, SCO1/SenC, score 2.9e-35 216591003966 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591003967 YCII-related domain; Region: YCII; cl00999 216591003968 HMMPfam hit to PF03795, YCII-related domain, score 3.2e-15 216591003969 Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049 216591003970 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054 216591003971 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591003972 dimer interface [polypeptide binding]; other site 216591003973 putative CheW interface [polypeptide binding]; other site 216591003974 2 probable transmembrane helices predicted for BCAL0762 by TMHMM2.0 at aa 10-30 and 187-209 216591003975 HMMPfam hit to PF08269, Cache domain, score 4.2e-36 216591003976 HMMPfam hit to PF00672, HAMP domain, score 0.0075 216591003977 PS00538 Bacterial chemotaxis sensory transducers signature. 216591003978 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 5.5e-106 216591003979 ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464 216591003980 NLPA lipoprotein; Region: Lipoprotein_9; pfam03180 216591003981 HMMPfam hit to PF03180, NLPA lipoprotein, score 6.6e-133 216591003982 Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325 216591003983 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 216591003984 zinc binding site [ion binding]; other site 216591003985 putative ligand binding site [chemical binding]; other site 216591003986 1 probable transmembrane helix predicted for BCAL0765 by TMHMM2.0 at aa 7-29 216591003987 HMMPfam hit to PF04392, ABC transporter substrate binding protei, score 1.1e-127 216591003988 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591003989 Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574 216591003990 TM-ABC transporter signature motif; other site 216591003991 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.1e-26 216591003992 8 probable transmembrane helices predicted for BCAL0766 by TMHMM2.0 at aa 7-29, 59-81, 88-107, 131-153, 179-201, 211-230, 235-254 and 269-286 216591003993 ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101 216591003994 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591003995 Walker A/P-loop; other site 216591003996 ATP binding site [chemical binding]; other site 216591003997 Q-loop/lid; other site 216591003998 ABC transporter signature motif; other site 216591003999 Walker B; other site 216591004000 D-loop; other site 216591004001 H-loop/switch region; other site 216591004002 HMMPfam hit to PF00005, ABC transporter, score 8.3e-42 216591004003 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004004 PS00211 ABC transporters family signature. 216591004005 DNA Polymerase Y-family; Region: PolY_like; cd03468 216591004006 active site 216591004007 DNA binding site [nucleotide binding] 216591004008 error-prone DNA polymerase; Validated; Region: dnaE2; PRK05672 216591004009 Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at DnaE2 gene; Region: PHP_PolIIIA_DnaE2; cd07434 216591004010 putative active site [active] 216591004011 putative PHP Thumb interface [polypeptide binding]; other site 216591004012 DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485 216591004013 generic binding surface II; other site 216591004014 generic binding surface I; other site 216591004015 HMMPfam hit to PF02811, PHP domain, score 2.3e-08 216591004016 HMMPfam hit to PF07733, Bacterial DNA polymerase III alpha sub, score 2.7e-218 216591004017 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 1.1e-05 216591004018 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591004019 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591004020 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 216591004021 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 3.7e-36 216591004022 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591004023 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138 216591004024 conserved cys residue [active] 216591004025 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591004026 HMMPfam hit to PF01965, DJ-1/PfpI family, score 0.002 216591004027 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 0.00041 216591004028 Predicted helix-turn-helix motif with score 1206.000, SD 3.29 at aa 247-268, sequence HTIASLAGISCLTERTFIRRFQ 216591004029 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004030 PS00041 Bacterial regulatory proteins, araC family signature. 216591004031 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 7.2e-07 216591004032 Short chain fatty acids transporter [Lipid metabolism]; Region: AtoE; COG2031 216591004033 HMMPfam hit to PF02667, Short chain fatty acid transporter, score 1.3e-51 216591004034 9 probable transmembrane helices predicted for BCAL0773 by TMHMM2.0 at aa 47-69, 79-101, 122-144, 212-234, 268-287, 297-319, 331-353, 373-395 and 456-478 216591004035 ornithine cyclodeaminase; Validated; Region: PRK06141 216591004036 ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400 216591004037 HMMPfam hit to PF02423, Ornithine cyclodeaminase/mu-crystalli, score 6.3e-58 216591004038 Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243 216591004039 The MopB_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. Members...; Region: MopB_Acetylene-hydratase; cd02759 216591004040 putative [Fe4-S4] binding site [ion binding]; other site 216591004041 putative molybdopterin cofactor binding site [chemical binding]; other site 216591004042 The MopB_CT_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. This...; Region: MopB_CT_Acetylene-hydratase; cd02781 216591004043 putative molybdopterin cofactor binding site; other site 216591004044 FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184 216591004045 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018 216591004046 FAD binding pocket [chemical binding]; other site 216591004047 FAD binding motif [chemical binding]; other site 216591004048 phosphate binding motif [ion binding]; other site 216591004049 beta-alpha-beta structure motif; other site 216591004050 NAD binding pocket [chemical binding]; other site 216591004051 Heme binding pocket [chemical binding]; other site 216591004052 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591004053 Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633 216591004054 catalytic loop [active] 216591004055 iron binding site [ion binding]; other site 216591004056 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding do, score 5.1e-15 216591004057 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 3.7e-15 216591004058 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 1.9e-07 216591004059 HMMPfam hit to PF01568, Molydopterin dinucleotide binding dom, score 1.1e-24 216591004060 HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 5.2e-32 216591004061 HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 do, score 1.9e-05 216591004062 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591004063 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591004064 The C-terminal substrate-binding domain of putative LysR-type transcriptional regulator PAO1-like, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_PAO1_like; cd08412 216591004065 putative substrate binding pocket [chemical binding]; other site 216591004066 dimerization interface [polypeptide binding]; other site 216591004067 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.7e-19 216591004068 Predicted helix-turn-helix motif with score 1010.000, SD 2.63 at aa 20-41, sequence GQISKSANLCSVSQSSMTIALK 216591004069 PS00044 Bacterial regulatory proteins, lysR family signature. 216591004070 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.5e-39 216591004071 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 216591004072 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591004073 DNA-binding site [nucleotide binding]; DNA binding site 216591004074 The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866 216591004075 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2e-15 216591004076 PS00043 Bacterial regulatory proteins, gntR family signature. 216591004077 HMMPfam hit to PF07702, UTRA domain, score 1.9e-41 216591004078 N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820 216591004079 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854 216591004080 active site 216591004081 dimer interface [polypeptide binding]; other site 216591004082 HMMPfam hit to PF01979, Amidohydrolase family, score 8.4e-14 216591004083 Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222 216591004084 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 216591004085 dimer interface [polypeptide binding]; other site 216591004086 active site 216591004087 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 216591004088 dimer interface [polypeptide binding]; other site 216591004089 active site 216591004090 HMMPfam hit to PF01380, SIS domain, score 3.3e-10 216591004091 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004092 HMMPfam hit to PF01380, SIS domain, score 2.7e-14 216591004093 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591004094 Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190 216591004095 HPr interaction site; other site 216591004096 glycerol kinase (GK) interaction site [polypeptide binding]; other site 216591004097 active site 216591004098 phosphorylation site [posttranslational modification] 216591004099 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080 216591004100 PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524 216591004101 PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391 216591004102 PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 216591004103 HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar p, score 5.2e-54 216591004104 PS00371 PTS EIIA domains phosphorylation site signature 1. 216591004105 HMMPfam hit to PF00381, PTS HPr component phosphorylation sit, score 1e-12 216591004106 PS00369 PTS HPR component histidine phosphorylation site signature. 216591004107 HMMPfam hit to PF05524, PEP-utilising enzyme, N-terminal, score 5e-30 216591004108 HMMPfam hit to PF00391, PEP-utilising enzyme, mobile domain, score 3e-24 216591004109 PS00370 PEP-utilizing enzymes phosphorylation site signature. 216591004110 HMMPfam hit to PF02896, PEP-utilising enzyme, TIM barrel doma, score 3.7e-118 216591004111 PS00742 PEP-utilizing enzymes signature 2. 216591004112 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 216591004113 PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998 216591004114 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 216591004115 active site turn [active] 216591004116 phosphorylation site [posttranslational modification] 216591004117 12 probable transmembrane helices predicted for BCAL0781 by TMHMM2.0 at aa 12-34, 49-66, 71-88, 98-115, 135-154, 164-186, 193-215, 230-252, 261-283, 287-309, 311-333 and 337-359 216591004118 HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 1.3e-101 216591004119 HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 2.4e-11 216591004120 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 216591004121 HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 5.8e-05 216591004122 Putative carbohydrate binding domain; Region: CHB_HEX; cl03918 216591004123 Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948 216591004124 Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728 216591004125 active site 216591004126 HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyti, score 3.4e-159 216591004127 HMMPfam hit to PF03173, Putative carbohydrate binding domain, score 9.4e-18 216591004128 1 probable transmembrane helix predicted for BCAL0782 by TMHMM2.0 at aa 7-29 216591004129 Membrane bound YbgT-like protein; Region: YbgT_YccB; pfam08173 216591004130 HMMPfam hit to PF08173, Membrane bound YbgT-like protein, score 1.3e-14 216591004131 1 probable transmembrane helix predicted for BCAL0783 by TMHMM2.0 at aa 2-24 216591004132 cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219 216591004133 Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322 216591004134 HMMPfam hit to PF02322, Cytochrome oxidase subunit II, score 2.1e-169 216591004135 8 probable transmembrane helices predicted for BCAL0784 by TMHMM2.0 at aa 7-24, 77-99, 120-142, 162-184, 205-227, 262-284, 291-313 and 336-358 216591004136 cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097 216591004137 Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562 216591004138 HMMPfam hit to PF01654, Bacterial Cytochrome Ubiquinol Oxidase, score 1.4e-287 216591004139 9 probable transmembrane helices predicted for BCAL0785 by TMHMM2.0 at aa 15-37, 57-79, 94-116, 129-148, 188-210, 217-239, 390-412, 425-447 and 475-492 216591004140 1 probable transmembrane helix predicted for BCAL0786 by TMHMM2.0 at aa 34-53 216591004141 RNA polymerase factor sigma-32; Reviewed; Region: PRK06596 216591004142 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 216591004143 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591004144 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591004145 DNA binding residues [nucleotide binding] 216591004146 PS00716 Sigma-70 factors family signature 2. 216591004147 Predicted helix-turn-helix motif with score 1683.000, SD 4.92 at aa 276-297, sequence STLHDLAAEFGVSAERIRQIEA 216591004148 HMMPfam hit to PF04542, Sigma-70 region, score 2.6e-23 216591004149 PS00715 Sigma-70 factors family signature 1. 216591004150 Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411 216591004151 1 probable transmembrane helix predicted for BCAL0788 by TMHMM2.0 at aa 13-32 216591004152 SnoaL-like domain; Region: SnoaL_2; pfam12680 216591004153 Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119 216591004154 Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942 216591004155 active site 216591004156 catalytic residues [active] 216591004157 metal binding site [ion binding]; metal-binding site 216591004158 HMMPfam hit to PF00682, HMGL-like, score 1.7e-93 216591004159 PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 216591004160 PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 216591004161 glycosyl transferase family protein; Provisional; Region: PRK08136 216591004162 Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885 216591004163 HMMPfam hit to PF02885, Glycosyl transferase family, helical, score 1e-05 216591004164 GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042 216591004165 maleylacetoacetate isomerase; Region: maiA; TIGR01262 216591004166 C-terminal domain interface [polypeptide binding]; other site 216591004167 GSH binding site (G-site) [chemical binding]; other site 216591004168 putative dimer interface [polypeptide binding]; other site 216591004169 C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191 216591004170 dimer interface [polypeptide binding]; other site 216591004171 N-terminal domain interface [polypeptide binding]; other site 216591004172 maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site 216591004173 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 2.9e-10 216591004174 signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416 216591004175 SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963 216591004176 The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115 216591004177 P loop; other site 216591004178 GTP binding site [chemical binding]; other site 216591004179 HMMPfam hit to PF00448, SRP54-type protein, GTPase domain, score 2.7e-107 216591004180 PS00300 SRP54-type proteins GTP-binding domain signature. 216591004181 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004182 HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain, score 1.7e-13 216591004183 N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742 216591004184 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591004185 S-adenosylmethionine binding site [chemical binding]; other site 216591004186 HMMPfam hit to PF03602, Conserved hypothetical protein, score 6.4e-61 216591004187 PS00092 N-6 Adenine-specific DNA methylases signature. 216591004188 phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168 216591004189 Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163 216591004190 active site 216591004191 (T/H)XGH motif; other site 216591004192 HMMPfam hit to PF01467, Cytidylyltransferase, score 1.7e-27 216591004193 4Fe-4S dicluster domain; Region: Fer4_7; pfam12838 216591004194 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 2.2e-05 216591004195 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591004196 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079 216591004197 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591004198 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591004199 homodimer interface [polypeptide binding]; other site 216591004200 catalytic residue [active] 216591004201 HMMPfam hit to PF00155, Aminotransferase class I and II, score 4.8e-79 216591004202 Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462 216591004203 putative active site [active] 216591004204 catalytic residue [active] 216591004205 HMMPfam hit to PF01195, Peptidyl-tRNA hydrolase, score 6.1e-78 216591004206 PS01196 Peptidyl-tRNA hydrolase signature 2. 216591004207 PS01195 Peptidyl-tRNA hydrolase signature 1. 216591004208 50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618 216591004209 Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495 216591004210 5S rRNA interface [nucleotide binding]; other site 216591004211 CTC domain interface [polypeptide binding]; other site 216591004212 L16 interface [polypeptide binding]; other site 216591004213 HMMPfam hit to PF01386, Ribosomal L25p family, score 1.3e-22 216591004214 ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259 216591004215 N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793 216591004216 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 216591004217 active site 216591004218 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 4.7e-31 216591004219 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 216591004220 PS00114 Phosphoribosyl pyrophosphate synthetase signature. 216591004221 HMMPfam hit to PF08544, GHMP kinases C terminal, score 1.1e-05 216591004222 HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 1.6e-21 216591004223 outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022 216591004224 Outer membrane lipoprotein LolB; Region: LolB; pfam03550 216591004225 HMMPfam hit to PF03550, Outer membrane lipoprotein LolB, score 6.3e-26 216591004226 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004227 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591004228 TPR motif; other site 216591004229 binding surface 216591004230 FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457 216591004231 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591004232 binding surface 216591004233 TPR motif; other site 216591004234 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591004235 binding surface 216591004236 TPR motif; other site 216591004237 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.23 216591004238 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0034 216591004239 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.47 216591004240 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.096 216591004241 formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103 216591004242 N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966 216591004243 DNA binding site [nucleotide binding] 216591004244 catalytic residue [active] 216591004245 H2TH interface [polypeptide binding]; other site 216591004246 putative catalytic residues [active] 216591004247 turnover-facilitating residue; other site 216591004248 intercalation triad [nucleotide binding]; other site 216591004249 8OG recognition residue [nucleotide binding]; other site 216591004250 putative reading head residues; other site 216591004251 Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831 216591004252 Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827 216591004253 HMMPfam hit to PF01149, Formamidopyrimidine-DNA glycosylase N-, score 2.1e-40 216591004254 HMMPfam hit to PF06831, Formamidopyrimidine-DNA glycosylase H2, score 1.4e-31 216591004255 HMMPfam hit to PF06827, Zinc finger found in FPG and IleRS, score 0.00015 216591004256 PS01242 Formamidopyrimidine-DNA glycosylase signature. 216591004257 A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194 216591004258 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 216591004259 minor groove reading motif; other site 216591004260 helix-hairpin-helix signature motif; other site 216591004261 substrate binding pocket [chemical binding]; other site 216591004262 active site 216591004263 DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431 216591004264 DNA binding and oxoG recognition site [nucleotide binding] 216591004265 HMMPfam hit to PF00730, HhH-GPD superfamily base excision DNA repair, score 4.2e-20 216591004266 HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 3.4e-07 216591004267 ATP-dependent protease La (LON) domain; Region: LON; pfam02190 216591004268 HMMPfam hit to PF02190, ATP-dependent protease La (LON) domain, score 5.1e-07 216591004269 PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 216591004270 glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416 216591004271 HMMPfam hit to PF03668, P-loop ATPase protein family, score 3.3e-102 216591004272 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004273 HPr kinase/phosphorylase; Provisional; Region: PRK05428 216591004274 HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603 216591004275 HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918 216591004276 Hpr binding site; other site 216591004277 active site 216591004278 homohexamer subunit interaction site [polypeptide binding]; other site 216591004279 HMMPfam hit to PF07475, HPr Serine kinase C-terminus, score 1e-43 216591004280 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004281 CDS contains a nonsense mutation (amber) after codon 51. Similar to Pseudomonas aeruginosa nitrogen regulatory IIA protein PtsN UniProt:Q9HVV4 (EMBL:AE004860) (154 aa) fasta scores: E()=1.4e-15, 41.722% id in 151 aa. Possible alternative upstream translational start sites 216591004282 HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phosph, score 3.5e-09 216591004283 RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552 216591004284 30S subunit binding site; other site 216591004285 HMMPfam hit to PF02482, Sigma 54 modulation protein / S30EA r, score 9e-40 216591004286 RNA polymerase factor sigma-54; Reviewed; Region: PRK05932 216591004287 Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963 216591004288 Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552 216591004289 HMMPfam hit to PF04552, Sigma-54, DNA binding domain, score 3.9e-103 216591004290 PS00718 Sigma-54 factors family signature 2. 216591004291 Predicted helix-turn-helix motif with score 1921.000, SD 5.73 at aa 390-411, sequence LVLREIADTLGLHESTVSRVTT 216591004292 PS00717 Sigma-54 factors family signature 1. 216591004293 HMMPfam hit to PF04963, Sigma-54 factor, core binding domain, score 5.3e-79 216591004294 HMMPfam hit to PF00309, Sigma-54 factor, Activator interacting do, score 3.1e-18 216591004295 PS00041 Bacterial regulatory proteins, araC family signature. 216591004296 ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137 216591004297 ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218 216591004298 Walker A/P-loop; other site 216591004299 ATP binding site [chemical binding]; other site 216591004300 Q-loop/lid; other site 216591004301 ABC transporter signature motif; other site 216591004302 Walker B; other site 216591004303 D-loop; other site 216591004304 H-loop/switch region; other site 216591004305 HMMPfam hit to PF00005, ABC transporter, score 6e-57 216591004306 PS00211 ABC transporters family signature. 216591004307 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004308 lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002 216591004309 OstA-like protein; Region: OstA; pfam03968 216591004310 HMMPfam hit to PF03968, OstA-like protein, score 2e-49 216591004311 Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835 216591004312 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3117 216591004313 HMMPfam hit to PF06835, Protein of unknown function (DUF1239), score 5e-36 216591004314 1 probable transmembrane helix predicted for BCAL0816 by TMHMM2.0 at aa 5-27 216591004315 Low specificity phosphatase (HAD superfamily) [General function prediction only]; Region: COG1778 216591004316 HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662 216591004317 D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892 216591004318 KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014 216591004319 putative active site [active] 216591004320 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein. These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604 216591004321 HMMPfam hit to PF00571, CBS domain pair, score 1.7e-26 216591004322 HMMPfam hit to PF01380, SIS domain, score 9.2e-36 216591004323 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004324 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475 216591004325 TrkA-N domain; Region: TrkA_N; pfam02254 216591004326 12 probable transmembrane helices predicted for BCAL0819 by TMHMM2.0 at aa 5-24, 29-46, 56-75, 82-104, 114-136, 149-171, 181-200, 220-254, 269-286, 295-317, 327-349 and 356-378 216591004327 HMMPfam hit to PF00999, Sodium/hydrogen exchanger family, score 2.6e-75 216591004328 HMMPfam hit to PF02254, TrkA-N domain, score 3.2e-31 216591004329 HMMPfam hit to PF02080, TrkA-C domain, score 3.1e-10 216591004330 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 216591004331 active site 216591004332 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 1.7e-42 216591004333 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 216591004334 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591004335 HMMPfam hit to PF01810, LysE type translocator, score 8.5e-38 216591004336 5 probable transmembrane helices predicted for BCAL0821 by TMHMM2.0 at aa 37-59, 69-91, 112-134, 149-171 and 183-202 216591004337 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belong to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_hydrolase_3; cd03676 216591004338 nudix motif; other site 216591004339 HMMPfam hit to PF00293, NUDIX domain, score 1.3e-05 216591004340 formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027 216591004341 N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875 216591004342 Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648 216591004343 putative active site [active] 216591004344 putative substrate binding site [chemical binding]; other site 216591004345 putative cosubstrate binding site; other site 216591004346 catalytic site [active] 216591004347 HMMPfam hit to PF01842, ACT domain, score 0.00027 216591004348 HMMPfam hit to PF00551, Formyl transferase, score 4.5e-36 216591004349 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628 216591004350 7 probable transmembrane helices predicted for BCAL0824 by TMHMM2.0 at aa 43-65, 86-108, 172-194, 228-247, 257-274, 279-301 and 328-350 216591004351 excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349 216591004352 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 216591004353 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 216591004354 ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271 216591004355 HMMPfam hit to PF00005, ABC transporter, score 2.3e-35 216591004356 PS00211 ABC transporters family signature. 216591004357 PS00190 Cytochrome c family heme-binding site signature. 216591004358 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004359 PS00211 ABC transporters family signature. 216591004360 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004361 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591004362 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591004363 putative substrate translocation pore; other site 216591004364 12 probable transmembrane helices predicted for BCAL0826 by TMHMM2.0 at aa 21-43, 53-75, 87-104, 109-131, 143-165, 170-192, 213-235, 250-272, 279-296, 300-319, 340-362 and 366-385 216591004365 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.8e-54 216591004366 Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629 216591004367 SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496 216591004368 dimer interface [polypeptide binding]; other site 216591004369 ssDNA binding site [nucleotide binding]; other site 216591004370 tetramer (dimer of dimers) interface [polypeptide binding]; other site 216591004371 HMMPfam hit to PF00436, Single-strand binding protein family, score 3.7e-39 216591004372 PS00735 Single-strand binding protein family signature 1. 216591004373 PS00736 Single-strand binding protein family signature 2. 216591004374 G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028 216591004375 active site 216591004376 SUMO-1 interface [polypeptide binding]; other site 216591004377 HMMPfam hit to PF03167, Uracil DNA glycosylase superfamily, score 2.7e-23 216591004378 Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540 216591004379 active site 216591004380 DNA binding site [nucleotide binding] 216591004381 HMMPfam hit to PF02245, Methylpurine-DNA glycosylase (MPG), score 4.4e-56 216591004382 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004383 ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192 216591004384 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 216591004385 P-loop; other site 216591004386 Magnesium ion binding site [ion binding]; other site 216591004387 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 216591004388 Magnesium ion binding site [ion binding]; other site 216591004389 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 9.2e-28 216591004390 Phasin protein; Region: Phasin_2; pfam09361 216591004391 putative acyltransferase; Provisional; Region: PRK05790 216591004392 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 216591004393 dimer interface [polypeptide binding]; other site 216591004394 active site 216591004395 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 1e-177 216591004396 PS00098 Thiolases acyl-enzyme intermediate signature. 216591004397 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 3.8e-85 216591004398 PS00737 Thiolases signature 2. 216591004399 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004400 PS00099 Thiolases active site. 216591004401 acetoacetyl-CoA reductase; Region: AcAcCoA_reduct; TIGR01829 216591004402 beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333 216591004403 NAD(P) binding site [chemical binding]; other site 216591004404 homotetramer interface [polypeptide binding]; other site 216591004405 homodimer interface [polypeptide binding]; other site 216591004406 active site 216591004407 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.003 216591004408 HMMPfam hit to PF00106, short chain dehydrogenase, score 4.1e-42 216591004409 PS00061 Short-chain dehydrogenases/reductases family signature. 216591004410 1 probable transmembrane helix predicted for BCAL0834 by TMHMM2.0 at aa 5-27 216591004411 1 probable transmembrane helix predicted for BCAL0835 by TMHMM2.0 at aa 13-32 216591004412 Domain of unknown function, appears to be related to a diverse group of beta-hydroxydecanoyl ACP dehydratases (FabA) and beta-hydroxyacyl ACP dehydratases (FabZ). This group appears to lack the conserved active site histidine of FabA and FabZ; Region: FabA_like; cd01289 216591004413 putative active site 1 [active] 216591004414 Beta-ketoacyl synthase, N-terminal domain; Region: Ketoacyl-synt_2; pfam13723 216591004415 3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK09185 216591004416 Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834 216591004417 dimer interface [polypeptide binding]; other site 216591004418 active site 216591004419 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 1.4e-50 216591004420 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 7.9e-09 216591004421 PS00606 Beta-ketoacyl synthases active site. 216591004422 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004423 Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726 216591004424 Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917 216591004425 NodB motif; other site 216591004426 active site 216591004427 catalytic site [active] 216591004428 metal binding site [ion binding]; metal-binding site 216591004429 HMMPfam hit to PF01522, Polysaccharide deacetylase, score 7.2e-35 216591004430 Predicted exporter [General function prediction only]; Region: COG4258 216591004431 12 probable transmembrane helices predicted for BCAL0840 by TMHMM2.0 at aa 21-43, 264-281, 288-310, 314-336, 357-379, 389-408, 438-455, 674-692, 699-721, 725-744, 757-779 and 789-811 216591004432 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004433 HMMPfam hit to PF03176, MMPL family, score 9.3e-05 216591004434 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004435 Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548 216591004436 1 probable transmembrane helix predicted for BCAL0841 by TMHMM2.0 at aa 17-39 216591004437 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984 216591004438 putative acyl-acceptor binding pocket; other site 216591004439 1 probable transmembrane helix predicted for BCAL0842 by TMHMM2.0 at aa 35-54 216591004440 O-succinylbenzoate-CoA ligase; Region: menE; TIGR01923 216591004441 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591004442 acyl-activating enzyme (AAE) consensus motif; other site 216591004443 AMP binding site [chemical binding]; other site 216591004444 active site 216591004445 CoA binding site [chemical binding]; other site 216591004446 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591004447 PS00012 Phosphopantetheine attachment site. 216591004448 Predicted membrane protein [Function unknown]; Region: COG4648 216591004449 5 probable transmembrane helices predicted for BCAL0844 by TMHMM2.0 at aa 5-27, 32-54, 61-78, 98-120 and 141-163 216591004450 acyl carrier protein; Provisional; Region: PRK09184 216591004451 PS00012 Phosphopantetheine attachment site. 216591004452 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 216591004453 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591004454 NAD(P) binding site [chemical binding]; other site 216591004455 active site 216591004456 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.9e-34 216591004457 This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_5; cd06153 216591004458 homotrimer interaction site [polypeptide binding]; other site 216591004459 putative active site [active] 216591004460 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 0.00072 216591004461 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 216591004462 DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179 216591004463 Ligand binding site; other site 216591004464 Putative Catalytic site; other site 216591004465 DXD motif; other site 216591004466 HMMPfam hit to PF00535, Glycosyl transferase family, score 7e-20 216591004467 Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501 216591004468 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004469 HMMPfam hit to PF01435, Peptidase family M48, score 4.8e-30 216591004470 L-lactate permease; Region: Lactate_perm; cl00701 216591004471 glycolate transporter; Provisional; Region: PRK09695 216591004472 11 probable transmembrane helices predicted for BCAL0850 by TMHMM2.0 at aa 13-35, 40-62, 69-91, 128-150, 157-179, 194-213, 320-342, 383-402, 423-442, 447-469 and 543-565 216591004473 HMMPfam hit to PF02652, L-lactate permease, score 1.5e-266 216591004474 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004475 Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139 216591004476 Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589 216591004477 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 216591004478 Domain of unknown function (DUF3390); Region: DUF3390; pfam11870 216591004479 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0053 216591004480 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591004481 Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589 216591004482 HMMPfam hit to PF02589, Uncharacterized ACR, YkgG family COG1556, score 2.1e-13 216591004483 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 216591004484 Cysteine-rich domain; Region: CCG; pfam02754 216591004485 Cysteine-rich domain; Region: CCG; pfam02754 216591004486 HMMPfam hit to PF02754, Cysteine-rich domain, score 1.2e-14 216591004487 HMMPfam hit to PF02754, Cysteine-rich domain, score 1.9e-10 216591004488 Transcriptional regulators [Transcription]; Region: FadR; COG2186 216591004489 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591004490 DNA-binding site [nucleotide binding]; DNA binding site 216591004491 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 216591004492 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 5e-18 216591004493 HMMPfam hit to PF07729, FCD domain, score 2.8e-28 216591004494 Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502 216591004495 Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111 216591004496 putative active site [active] 216591004497 catalytic site [active] 216591004498 Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113 216591004499 putative active site [active] 216591004500 catalytic site [active] 216591004501 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 0.00024 216591004502 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 0.00049 216591004503 aldolase II superfamily protein; Provisional; Region: PRK07044 216591004504 intersubunit interface [polypeptide binding]; other site 216591004505 active site 216591004506 Zn2+ binding site [ion binding]; other site 216591004507 HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 4.2e-59 216591004508 MltA-interacting protein MipA; Region: MipA; cl01504 216591004509 CHRD domain; Region: CHRD; pfam07452 216591004510 HMMPfam hit to PF07452, CHRD domain, score 1.9e-21 216591004511 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 216591004512 HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 7e-84 216591004513 PS01173 Lipolytic enzymes G-D-X-G family, putative histidine active site. 216591004514 EcsC protein family; Region: EcsC; pfam12787 216591004515 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591004516 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591004517 putative substrate translocation pore; other site 216591004518 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591004519 14 probable transmembrane helices predicted for BCAL0861 by TMHMM2.0 at aa 20-42, 57-79, 88-107, 112-134, 147-169, 179-198, 211-233, 238-257, 277-299, 314-336, 343-365, 369-391, 403-425 and 490-512 216591004520 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.8e-56 216591004521 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004522 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004523 Transcriptional regulators [Transcription]; Region: MarR; COG1846 216591004524 Winged helix DNA-binding domain; Region: HTH_27; pfam13463 216591004525 HMMPfam hit to PF01047, MarR family, score 5.5e-15 216591004526 intracellular protease, PfpI family; Region: PfpI; TIGR01382 216591004527 Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_1; cd03169 216591004528 conserved cys residue [active] 216591004529 HMMPfam hit to PF01965, DJ-1/PfpI family, score 2.4e-49 216591004530 Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616 216591004531 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase; Region: PLPDE_III_cryptic_DSD; cd06818 216591004532 dimer interface [polypeptide binding]; other site 216591004533 active site 216591004534 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 216591004535 substrate binding site [chemical binding]; other site 216591004536 catalytic residue [active] 216591004537 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 216591004538 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 216591004539 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 216591004540 putative active site [active] 216591004541 HMMPfam hit to PF01418, Helix-turn-helix domain, rpiR family, score 2e-05 216591004542 HMMPfam hit to PF01380, SIS domain, score 2.5e-22 216591004543 N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653 216591004544 D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics; Region: D-aminoacylase; cd01297 216591004545 active site 216591004546 putative substrate binding pocket [chemical binding]; other site 216591004547 HMMPfam hit to PF01979, Amidohydrolase family, score 0.0036 216591004548 HMMPfam hit to PF07969, Amidohydrolase family, score 3.7e-32 216591004549 HMMPfam hit to PF07908, D-aminoacylase, C-terminal region, score 5.3e-21 216591004550 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 216591004551 homotrimer interaction site [polypeptide binding]; other site 216591004552 putative active site [active] 216591004553 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 3e-30 216591004554 7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792 216591004555 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904 216591004556 Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780 216591004557 HMMPfam hit to PF01227, GTP cyclohydrolase I, score 8.8e-11 216591004558 threonine dehydratase; Reviewed; Region: PRK09224 216591004559 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 216591004560 tetramer interface [polypeptide binding]; other site 216591004561 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591004562 catalytic residue [active] 216591004563 First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906 216591004564 putative Ile/Val binding site [chemical binding]; other site 216591004565 Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907 216591004566 putative Ile/Val binding site [chemical binding]; other site 216591004567 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 216591004568 Protein of unknown function (DUF3683); Region: DUF3683; pfam12447 216591004569 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 216591004570 FAD binding domain; Region: FAD_binding_4; pfam01565 216591004571 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 216591004572 4Fe-4S dicluster domain; Region: Fer4_8; pfam13183 216591004573 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 216591004574 Cysteine-rich domain; Region: CCG; pfam02754 216591004575 Domain of unknown function (DUF3400); Region: DUF3400; pfam11880 216591004576 HMMPfam hit to PF01565, FAD binding domain, score 7.6e-27 216591004577 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004578 HMMPfam hit to PF02913, FAD linked oxidases, C-terminal domain, score 9.6e-09 216591004579 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591004580 PS00190 Cytochrome c family heme-binding site signature. 216591004581 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 216591004582 HMMPfam hit to PF02754, Cysteine-rich domain, score 0.004 216591004583 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537 216591004584 nucleotide binding site/active site [active] 216591004585 HIT family signature motif; other site 216591004586 catalytic residue [active] 216591004587 HMMPfam hit to PF01230, HIT domain, score 7e-19 216591004588 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3536 216591004589 HMMPfam hit to PF06155, Protein of unknown function (DUF971), score 4.6e-49 216591004590 Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226 216591004591 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591004592 S-adenosylmethionine binding site [chemical binding]; other site 216591004593 HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 1.1e-114 216591004594 PS01183 ubiE/COQ5 methyltransferase family signature 1. 216591004595 HMMPfam hit to PF08241, Methyltransferase domain, score 1.3e-25 216591004596 HMMPfam hit to PF08242, Methyltransferase domain, score 1.1e-13 216591004597 Tim44-like domain; Region: Tim44; pfam04280 216591004598 2 probable transmembrane helices predicted for BCAL0874 by TMHMM2.0 at aa 21-38 and 123-145 216591004599 HMMPfam hit to PF04280, Tim44-like domain, score 3e-05 216591004600 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165 216591004601 SCP-2 sterol transfer family; Region: SCP2; pfam02036 216591004602 HMMPfam hit to PF06843, Protein of unknown function (DUF1243), score 1e-27 216591004603 putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750 216591004604 2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982 216591004605 HMMPfam hit to PF03109, ABC1 family, score 2.3e-46 216591004606 1 probable transmembrane helix predicted for BCAL0876 by TMHMM2.0 at aa 497-519 216591004607 Thiopurine S-methyltransferase (TPMT); Region: TPMT; pfam05724 216591004608 HMMPfam hit to PF05724, Thiopurine S-methyltransferase (TPMT), score 1.4e-38 216591004609 HMMPfam hit to PF08242, Methyltransferase domain, score 7.3e-08 216591004610 Zinc ribbon domain; Region: CxxC_CxxC_SSSS; cl00993 216591004611 Uncharacterized conserved protein [Function unknown]; Region: COG2928 216591004612 2 probable transmembrane helices predicted for BCAL0879 by TMHMM2.0 at aa 9-31 and 51-73 216591004613 HMMPfam hit to PF04367, Protein of unknown function (DUF502), score 2e-57 216591004614 aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476 216591004615 EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317 216591004616 dimer interface [polypeptide binding]; other site 216591004617 anticodon binding site; other site 216591004618 Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777 216591004619 homodimer interface [polypeptide binding]; other site 216591004620 motif 1; other site 216591004621 active site 216591004622 motif 2; other site 216591004623 GAD domain; Region: GAD; pfam02938 216591004624 Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777 216591004625 motif 3; other site 216591004626 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 4.9e-27 216591004627 HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 1.5e-210 216591004628 HMMPfam hit to PF00587, tRNA synthetase class II core domain (G,, score 0.0048 216591004629 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591004630 HMMPfam hit to PF02938, GAD domain, score 5.9e-39 216591004631 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591004632 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664 216591004633 nudix motif; other site 216591004634 HMMPfam hit to PF00293, NUDIX domain, score 5.2e-16 216591004635 Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110 216591004636 PLD-like domain; Region: PLDc_2; pfam13091 216591004637 putative active site [active] 216591004638 catalytic site [active] 216591004639 Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159 216591004640 PLD-like domain; Region: PLDc_2; pfam13091 216591004641 putative active site [active] 216591004642 catalytic site [active] 216591004643 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 0.00072 216591004644 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 0.063 216591004645 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591004646 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591004647 Predicted helix-turn-helix motif with score 1038.000, SD 2.72 at aa 27-48, sequence LTIGLLAERMQMSKSGVFAHFG 216591004648 acyl-CoA dehydrogenase; Provisional; Region: PTZ00456 216591004649 Acyl-CoA dehydrogenase N terminal; Region: AcylCoA_DH_N; pfam12418 216591004650 Putative acyl-CoA dehydrogenases similar to fadE5; Region: ACAD_fadE5; cd01153 216591004651 FAD binding site [chemical binding]; other site 216591004652 substrate binding site [chemical binding]; other site 216591004653 catalytic residues [active] 216591004654 Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806 216591004655 PS00216 Sugar transport proteins signature 1. 216591004656 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250 216591004657 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 216591004658 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 216591004659 Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024 216591004660 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591004661 substrate binding site [chemical binding]; other site 216591004662 oxyanion hole (OAH) forming residues; other site 216591004663 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD binding, score 1.1e-65 216591004664 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 8.5e-10 216591004665 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 3.6e-09 216591004666 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004667 acetyl-CoA acetyltransferase; Provisional; Region: PRK09052 216591004668 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 216591004669 dimer interface [polypeptide binding]; other site 216591004670 active site 216591004671 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 1.9e-92 216591004672 PS00098 Thiolases acyl-enzyme intermediate signature. 216591004673 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 1.5e-63 216591004674 PS00737 Thiolases signature 2. 216591004675 PS00099 Thiolases active site. 216591004676 enoyl-CoA hydratase; Provisional; Region: PRK06688 216591004677 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591004678 substrate binding site [chemical binding]; other site 216591004679 oxyanion hole (OAH) forming residues; other site 216591004680 trimer interface [polypeptide binding]; other site 216591004681 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cl15762 216591004682 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 1.8e-45 216591004683 formate dehydrogenase accessory protein; Reviewed; Region: PRK00724 216591004684 HMMPfam hit to PF02634, FdhD/NarQ family, score 4.4e-69 216591004685 Conserved nitrate reductase-associated protein (Nitr_red_assoc); Region: Nitr_red_assoc; pfam09655 216591004686 Brown fat-inducible thioesterase (BFIT). Brain acyl-CoA hydrolase (BACH). These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442 216591004687 HMMPfam hit to PF03061, Thioesterase superfamily, score 9.6e-17 216591004688 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 216591004689 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265 216591004690 ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; Region: ABCC_ATM1_transporter; cd03253 216591004691 Walker A/P-loop; other site 216591004692 ATP binding site [chemical binding]; other site 216591004693 Q-loop/lid; other site 216591004694 ABC transporter signature motif; other site 216591004695 Walker B; other site 216591004696 D-loop; other site 216591004697 H-loop/switch region; other site 216591004698 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591004699 6 probable transmembrane helices predicted for BCAL0891 by TMHMM2.0 at aa 36-58, 78-100, 166-188, 193-215, 273-295 and 310-332 216591004700 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 3.5e-34 216591004701 HMMPfam hit to PF00005, ABC transporter, score 1.1e-59 216591004702 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004703 PS00211 ABC transporters family signature. 216591004704 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208 216591004705 NTP_transferase_like_1 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_1; cd06422 216591004706 Substrate binding site; other site 216591004707 metal-binding site 216591004708 HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.5e-12 216591004709 PS00092 N-6 Adenine-specific DNA methylases signature. 216591004710 Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only]; Region: COG3178 216591004711 Phosphotransferase enzyme family; Region: APH; pfam01636 216591004712 HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 4.6e-25 216591004713 Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452 216591004714 Organic solvent tolerance protein; Region: OstA_C; pfam04453 216591004715 HMMPfam hit to PF04453, Organic solvent tolerance protein, score 1.6e-121 216591004716 SurA N-terminal domain; Region: SurA_N; pfam09312 216591004717 peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770 216591004718 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 216591004719 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 216591004720 HMMPfam hit to PF00639, PPIC-type PPIASE domain, score 2.7e-17 216591004721 HMMPfam hit to PF00639, PPIC-type PPIASE domain, score 1.6e-30 216591004722 4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK01909 216591004723 4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743 216591004724 HMMPfam hit to PF04166, Pyridoxal phosphate biosynthetic protein Pdx, score 5.1e-140 216591004725 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274 216591004726 Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030 216591004727 HMMPfam hit to PF00398, Ribosomal RNA adenine dimethylase, score 3.5e-49 216591004728 EamA-like transporter family; Region: EamA; pfam00892 216591004729 10 probable transmembrane helices predicted for BCAL0898 by TMHMM2.0 at aa 13-35, 40-62, 75-97, 107-126, 133-150, 165-187, 200-222, 232-254, 259-281 and 285-307 216591004730 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 3.2e-17 216591004731 PS00063 Aldo/keto reductase family putative active site signature. 216591004732 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 8.7e-11 216591004733 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591004734 Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233 216591004735 dimer interface [polypeptide binding]; other site 216591004736 active site 216591004737 metal binding site [ion binding]; metal-binding site 216591004738 glutathione binding site [chemical binding]; other site 216591004739 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 2.2e-47 216591004740 PS00934 Glyoxalase I signature 1. 216591004741 Protein of unknown function DUF45; Region: DUF45; pfam01863 216591004742 HMMPfam hit to PF01863, Protein of unknown function DUF45, score 8.1e-81 216591004743 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204 216591004744 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 216591004745 putative acyl-acceptor binding pocket; other site 216591004746 HMMPfam hit to PF01553, Acyltransferase, score 7.1e-24 216591004747 1 probable transmembrane helix predicted for BCAL0901 by TMHMM2.0 at aa 7-29 216591004748 D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942 216591004749 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591004750 active site 216591004751 motif I; other site 216591004752 motif II; other site 216591004753 glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233 216591004754 Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020 216591004755 HMMPfam hit to PF05746, DALR anticodon binding domain, score 1.9e-08 216591004756 HMMPfam hit to PF02092, Glycyl-tRNA synthetase beta subunit, score 2e-188 216591004757 Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733 216591004758 dimer interface [polypeptide binding]; other site 216591004759 motif 1; other site 216591004760 active site 216591004761 motif 2; other site 216591004762 motif 3; other site 216591004763 HMMPfam hit to PF02091, Glycyl-tRNA synthetase alpha subunit, score 6.4e-220 216591004764 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591004765 TPR repeat; Region: TPR_11; pfam13414 216591004766 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591004767 binding surface 216591004768 TPR motif; other site 216591004769 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591004770 binding surface 216591004771 TPR motif; other site 216591004772 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 216591004773 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.42 216591004774 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.41 216591004775 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 9.1e-05 216591004776 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004777 apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302 216591004778 Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571 216591004779 putative active site [active] 216591004780 catalytic triad [active] 216591004781 putative dimer interface [polypeptide binding]; other site 216591004782 7 probable transmembrane helices predicted for BCAL0906 by TMHMM2.0 at aa 37-59, 71-93, 108-130, 151-173, 188-210, 242-264 and 533-552 216591004783 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 1.6e-10 216591004784 Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535 216591004785 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 216591004786 Transporter associated domain; Region: CorC_HlyC; smart01091 216591004787 HMMPfam hit to PF03471, Transporter associated domain, score 3.6e-22 216591004788 HMMPfam hit to PF00571, CBS domain pair, score 7.7e-22 216591004789 GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661 216591004790 putative active site pocket [active] 216591004791 dimerization interface [polypeptide binding]; other site 216591004792 putative catalytic residue [active] 216591004793 HMMPfam hit to PF04752, ChaC-like protein, score 2.6e-40 216591004794 unkown domain/putative metalloprotease fusion protein; Provisional; Region: PRK13963 216591004795 HMMPfam hit to PF02130, Uncharacterized protein family UPF0054, score 2.2e-31 216591004796 Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702 216591004797 PhoH-like protein; Region: PhoH; pfam02562 216591004798 HMMPfam hit to PF02562, PhoH-like protein, score 5.3e-138 216591004799 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004800 (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325 216591004801 Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919 216591004802 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591004803 FeS/SAM binding site; other site 216591004804 TRAM domain; Region: TRAM; pfam01938 216591004805 HMMPfam hit to PF01938, TRAM domain, score 2.4e-17 216591004806 HMMPfam hit to PF04055, Radical SAM superfamily, score 7.9e-34 216591004807 PS01278 Uncharacterized protein family UPF0004 signature. 216591004808 HMMPfam hit to PF00919, Uncharacterized protein family UPF0004, score 2.9e-44 216591004809 transcriptional regulator; Provisional; Region: PRK10632 216591004810 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591004811 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591004812 putative effector binding pocket; other site 216591004813 dimerization interface [polypeptide binding]; other site 216591004814 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.5e-46 216591004815 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6e-18 216591004816 PS00044 Bacterial regulatory proteins, lysR family signature. 216591004817 Predicted helix-turn-helix motif with score 1213.000, SD 3.32 at aa 17-38, sequence GSLSAAGRKLNLTPAAASARLA 216591004818 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591004819 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591004820 putative substrate translocation pore; other site 216591004821 12 probable transmembrane helices predicted for BCAL0913 by TMHMM2.0 at aa 5-27, 42-61, 73-95, 99-121, 128-150, 160-179, 200-222, 237-256, 263-282, 287-309, 329-351 and 355-374 216591004822 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.8e-50 216591004823 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591004824 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591004825 non-specific DNA binding site [nucleotide binding]; other site 216591004826 salt bridge; other site 216591004827 sequence-specific DNA binding site [nucleotide binding]; other site 216591004828 Cupin domain; Region: Cupin_2; pfam07883 216591004829 HMMPfam hit to PF01381, Helix-turn-helix, score 8.8e-14 216591004830 Predicted helix-turn-helix motif with score 1281.000, SD 3.55 at aa 48-69, sequence LSLDALARLSGVSRAMLAQIES 216591004831 HMMPfam hit to PF07883, Cupin domain, score 8.1e-06 216591004832 3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108 216591004833 3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353 216591004834 HMMPfam hit to PF00926, 3,4-dihydroxy-2-butanone 4-phosphate sy, score 1.7e-107 216591004835 Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637 216591004836 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591004837 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.6e-18 216591004838 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 216591004839 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 216591004840 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 216591004841 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 7.7e-06 216591004842 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 3e-24 216591004843 Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130 216591004844 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 1.2e-20 216591004845 PS00213 Lipocalin signature. 216591004846 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 0.004 216591004847 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591004848 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591004849 Periplasmic sugar-binding domain of uncharacterized transport systems; Region: PBP1_uncharacterized_sugar_binding; cd06307 216591004850 putative ligand binding site [chemical binding]; other site 216591004851 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 216591004852 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI family, score 3.1e-05 216591004853 Predicted helix-turn-helix motif with score 1285.000, SD 3.56 at aa 14-35, sequence ARFDEIAALAGVSTTTVDRVLN 216591004854 Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239 216591004855 This CD includes the putative hydrocarbon oxygenase, MocD, a bacterial rhizopine (3-O-methyl-scyllo-inosamine, 3-O-MSI) oxygenase, and other related proteins. It has been proposed that MocD, MocE (Rieske-like ferredoxin), and MocF (ferredoxin reductase)...; Region: Rhizopine-oxygenase-like; cd03511 216591004856 putative di-iron ligands [ion binding]; other site 216591004857 4 probable transmembrane helices predicted for BCAL0921 by TMHMM2.0 at aa 65-82, 87-104, 222-244 and 249-271 216591004858 HMMPfam hit to PF00487, Fatty acid desaturase, score 3.9e-19 216591004859 Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528 216591004860 [2Fe-2S] cluster binding site [ion binding]; other site 216591004861 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 9.3e-20 216591004862 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992 216591004863 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591004864 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 9.4e-48 216591004865 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 1.1e-29 216591004866 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580 216591004867 amphipathic channel; other site 216591004868 Asn-Pro-Ala signature motifs; other site 216591004869 6 probable transmembrane helices predicted for BCAL0924 by TMHMM2.0 at aa 5-27, 40-62, 82-104, 134-153, 163-185 and 212-234 216591004870 HMMPfam hit to PF00230, Major intrinsic protein, score 9.3e-26 216591004871 glycerol kinase; Provisional; Region: glpK; PRK00047 216591004872 Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786 216591004873 N- and C-terminal domain interface [polypeptide binding]; other site 216591004874 active site 216591004875 MgATP binding site [chemical binding]; other site 216591004876 catalytic site [active] 216591004877 metal binding site [ion binding]; metal-binding site 216591004878 glycerol binding site [chemical binding]; other site 216591004879 homotetramer interface [polypeptide binding]; other site 216591004880 homodimer interface [polypeptide binding]; other site 216591004881 FBP binding site [chemical binding]; other site 216591004882 protein IIAGlc interface [polypeptide binding]; other site 216591004883 HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 1.7e-88 216591004884 PS00445 FGGY family of carbohydrate kinases signature 2. 216591004885 HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 1.5e-115 216591004886 PS00933 FGGY family of carbohydrate kinases signature 1. 216591004887 glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266 216591004888 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2.6e-64 216591004889 PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 216591004890 1 probable transmembrane helix predicted for BCAL0927 by TMHMM2.0 at aa 7-26 216591004891 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004892 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 216591004893 DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220 216591004894 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 216591004895 HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 6e-59 216591004896 HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 4.1e-22 216591004897 HMMPfam hit to PF08279, HTH domain, score 0.00056 216591004898 Predicted helix-turn-helix motif with score 1213.000, SD 3.32 at aa 26-47, sequence VTVDDLAAHFAVTPQTIRRDVN 216591004899 PS00894 Bacterial regulatory proteins, deoR family signature. 216591004900 Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405 216591004901 Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019 216591004902 HMMPfam hit to PF01019, Gamma-glutamyltranspeptidase, score 1.2e-195 216591004903 PS00678 Trp-Asp (WD) repeats signature. 216591004904 Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657 216591004905 dinuclear metal binding motif [ion binding]; other site 216591004906 helicase 45; Provisional; Region: PTZ00424 216591004907 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 216591004908 ATP binding site [chemical binding]; other site 216591004909 Mg++ binding site [ion binding]; other site 216591004910 motif III; other site 216591004911 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591004912 nucleotide binding region [chemical binding]; other site 216591004913 ATP-binding site [chemical binding]; other site 216591004914 PS00036 bZIP transcription factors basic domain signature. 216591004915 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 8e-34 216591004916 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 4.5e-71 216591004917 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 216591004918 Predicted helix-turn-helix motif with score 1110.000, SD 2.97 at aa 83-104, sequence TPTRELAAQVEESVRAYSKYLK 216591004919 PS00017 ATP/GTP-binding site motif A (P-loop). 216591004920 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591004921 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591004922 Cytochrome c; Region: Cytochrom_C; pfam00034 216591004923 HMMPfam hit to PF00034, Cytochrome c, score 3e-06 216591004924 PS00190 Cytochrome c family heme-binding site signature. 216591004925 PS00190 Cytochrome c family heme-binding site signature. 216591004926 PS00190 Cytochrome c family heme-binding site signature. 216591004927 1 probable transmembrane helix predicted for BCAL0934 by TMHMM2.0 at aa 5-27 216591004928 Cytochrome c; Region: Cytochrom_C; cl11414 216591004929 Cytochrome c; Region: Cytochrom_C; cl11414 216591004930 PS00190 Cytochrome c family heme-binding site signature. 216591004931 PS00190 Cytochrome c family heme-binding site signature. 216591004932 Copper resistance protein D; Region: CopD; pfam05425 216591004933 9 probable transmembrane helices predicted for BCAL0936 by TMHMM2.0 at aa 21-43, 66-88, 95-112, 116-135, 142-164, 179-201, 222-244, 254-276 and 296-318 216591004934 HMMPfam hit to PF05425, Copper resistance protein D, score 5.6e-07 216591004935 galactonate dehydratase; Provisional; Region: PRK14017 216591004936 D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325 216591004937 putative active site pocket [active] 216591004938 putative metal binding site [ion binding]; other site 216591004939 HMMPfam hit to PF01188, Mandelate racemase / muconate lactonizing en, score 1.8e-29 216591004940 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591004941 PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 216591004942 HMMPfam hit to PF02746, Mandelate racemase / muconate lactonizing en, score 9.4e-49 216591004943 PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 216591004944 Probable gene remnant, CDS lacks appropriate translational start site. Similar to the C-terminal regions of Burkholderia ambifaria AMMD regulatory protein GntR bacterial regulatory protein UniProt:Q3FIX3 (EMBL:AAJL01000001) (252 aa) fasta scores: E()=2.1e-75, 91.597% id in 238 aa, and Rhizobium loti (Mesorhizobium loti) probable transcriptional regulator UniProt:Q98K08 (EMBL:BA000012) (260 aa) fasta scores: E()=2.3e-26, 43.256% id in 215 aa 216591004945 HMMPfam hit to PF07729, FCD domain, score 4.3e-29 216591004946 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3813 216591004947 Protein of unknown function (DUF1272); Region: DUF1272; pfam06906 216591004948 HMMPfam hit to PF06906, Protein of unknown function (DUF1272), score 1.3e-48 216591004949 Uncharacterized conserved protein [Function unknown]; Region: COG3791 216591004950 HMMPfam hit to PF04828, Protein of unknown function (DUF636), score 4.1e-20 216591004951 Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744 216591004952 Transglycosylase; Region: Transgly; cl17702 216591004953 HMMPfam hit to PF00912, Transglycosylase, score 0.00023 216591004954 1 probable transmembrane helix predicted for BCAL0940 by TMHMM2.0 at aa 21-43 216591004955 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591004956 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591004957 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591004958 putative effector binding pocket; other site 216591004959 dimerization interface [polypeptide binding]; other site 216591004960 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.9e-43 216591004961 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.5e-15 216591004962 PS00044 Bacterial regulatory proteins, lysR family signature. 216591004963 Predicted helix-turn-helix motif with score 1045.000, SD 2.75 at aa 17-38, sequence RSFARAATELNISNSSATRLVM 216591004964 PAAR motif; Region: PAAR_motif; pfam05488 216591004965 Cupin domain; Region: Cupin_2; cl17218 216591004966 HMMPfam hit to PF07883, Cupin domain, score 0.0026 216591004967 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 216591004968 Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139 216591004969 conserved cys residue [active] 216591004970 HMMPfam hit to PF01965, DJ-1/PfpI family, score 3.2e-24 216591004971 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591004972 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 216591004973 conserved cys residue [active] 216591004974 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591004975 HMMPfam hit to PF01965, DJ-1/PfpI family, score 2.4e-20 216591004976 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 0.00067 216591004977 PS00041 Bacterial regulatory proteins, araC family signature. 216591004978 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.8e-07 216591004979 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591004980 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591004981 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472 216591004982 putative effector binding pocket; other site 216591004983 putative dimerization interface [polypeptide binding]; other site 216591004984 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.8e-15 216591004985 PS00044 Bacterial regulatory proteins, lysR family signature. 216591004986 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.3e-44 216591004987 BcenGI4 216591004988 Plasmid recombination enzyme; Region: Mob_Pre; pfam01076 216591004989 HMMPfam hit to PF01076, Plasmid recombination enzyme, score 9.7e-20 216591004990 Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582 216591004991 INT_SG2, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 2, C-terminal catalytic domain. The CD contains mainly predicted integrase/recombinases and phage-related integrases. Some have N-terminal domains, which show little sequence...; Region: INT_SG2_C; cd01184 216591004992 Int/Topo IB signature motif; other site 216591004993 HMMPfam hit to PF00589, Phage integrase family, score 0.00076 216591004994 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591004995 putative substrate translocation pore; other site 216591004996 HMMPfam hit to PF00083, Sugar (and other) transporter, score 9.1e-12 216591004997 12 probable transmembrane helices predicted for BCAL0950 by TMHMM2.0 at aa 21-43, 58-80, 93-110, 114-136, 157-179, 194-213, 248-270, 285-307, 314-331, 455-477, 490-512 and 522-540 216591004998 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.1e-15 216591004999 PS00217 Sugar transport proteins signature 2. 216591005000 Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521 216591005001 HAMP domain; Region: HAMP; pfam00672 216591005002 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591005003 dimer interface [polypeptide binding]; other site 216591005004 phosphorylation site [posttranslational modification] 216591005005 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591005006 ATP binding site [chemical binding]; other site 216591005007 Mg2+ binding site [ion binding]; other site 216591005008 G-X-G motif; other site 216591005009 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 6.7e-36 216591005010 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.1e-17 216591005011 HMMPfam hit to PF00672, HAMP domain, score 1.3e-10 216591005012 2 probable transmembrane helices predicted for BCAL0951 by TMHMM2.0 at aa 51-73 and 204-226 216591005013 HMMPfam hit to PF08521, Two-component sensor kinase N-terminal, score 1.7e-57 216591005014 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591005015 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591005016 active site 216591005017 phosphorylation site [posttranslational modification] 216591005018 intermolecular recognition site; other site 216591005019 dimerization interface [polypeptide binding]; other site 216591005020 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591005021 DNA binding site [nucleotide binding] 216591005022 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 4.8e-21 216591005023 HMMPfam hit to PF00072, Response regulator receiver domain, score 4.4e-38 216591005024 recombinase A; Provisional; Region: recA; PRK09354 216591005025 RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983 216591005026 hexamer interface [polypeptide binding]; other site 216591005027 Walker A motif; other site 216591005028 ATP binding site [chemical binding]; other site 216591005029 Walker B motif; other site 216591005030 HMMPfam hit to PF00154, recA bacterial DNA recombination protein, score 3.2e-246 216591005031 PS00017 ATP/GTP-binding site motif A (P-loop). 216591005032 PS00321 recA signature. 216591005033 recombination regulator RecX; Provisional; Region: recX; PRK14136 216591005034 HMMPfam hit to PF02631, RecX family, score 0.0015 216591005035 Protein of unknown function (DUF2889); Region: DUF2889; pfam11136 216591005036 succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696 216591005037 ATP-grasp domain; Region: ATP-grasp_2; pfam08442 216591005038 CoA-ligase; Region: Ligase_CoA; pfam00549 216591005039 HMMPfam hit to PF08442, ATP-grasp domain, score 1.6e-116 216591005040 PS00063 Aldo/keto reductase family putative active site signature. 216591005041 HMMPfam hit to PF00549, CoA-ligase, score 5.8e-70 216591005042 PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 216591005043 succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678 216591005044 CoA binding domain; Region: CoA_binding; smart00881 216591005045 CoA-ligase; Region: Ligase_CoA; pfam00549 216591005046 HMMPfam hit to PF02629, CoA binding domain, score 7.2e-38 216591005047 HMMPfam hit to PF00549, CoA-ligase, score 1.6e-41 216591005048 PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 216591005049 PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 216591005050 integral membrane protein, YjbE family; Region: R_switched_YjbE; TIGR03717 216591005051 5 probable transmembrane helices predicted for BCAL0958 by TMHMM2.0 at aa 11-33, 46-68, 141-163, 168-190 and 205-224 216591005052 HMMPfam hit to PF03741, Integral membrane protein TerC family, score 6.4e-10 216591005053 Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544 216591005054 Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilA; COG4969 216591005055 Pilin (bacterial filament); Region: Pilin; pfam00114 216591005056 HMMPfam hit to PF07963, Prokaryotic N-terminal methylation motif, score 1.8e-06 216591005057 1 probable transmembrane helix predicted for BCAL0959 by TMHMM2.0 at aa 32-54 216591005058 O-Antigen ligase; Region: Wzy_C; pfam04932 216591005059 Domain of unknown function (DUF3366); Region: DUF3366; pfam11846 216591005060 12 probable transmembrane helices predicted for BCAL0960 by TMHMM2.0 at aa 13-35, 50-68, 75-97, 107-126, 133-155, 184-203, 210-229, 233-250, 262-284, 362-379, 391-413 and 433-455 216591005061 HMMPfam hit to PF04932, O-Antigen Polymerase, score 7.9e-14 216591005062 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005063 MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420 216591005064 trimer interface [polypeptide binding]; other site 216591005065 dimer interface [polypeptide binding]; other site 216591005066 putative active site [active] 216591005067 HMMPfam hit to PF01967, MoaC family, score 1.6e-75 216591005068 Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783 216591005069 Peptidase family M48; Region: Peptidase_M48; pfam01435 216591005070 HMMPfam hit to PF01435, Peptidase family M48, score 2.6e-32 216591005071 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591005072 Protein of unknown function (DUF2946); Region: DUF2944; pfam11161 216591005073 Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG0429 216591005074 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 7.6e-05 216591005075 SnoaL-like domain; Region: SnoaL_3; pfam13474 216591005076 Calcium/calmodulin dependent protein kinase II Association; Region: CaMKII_AD; cl17504 216591005077 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859 216591005078 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 216591005079 putative active site [active] 216591005080 HMMPfam hit to PF01075, Glycosyltransferase family, score 1.7e-89 216591005081 Zinc-finger domain; Region: zf-CHCC; cl01821 216591005082 Duplicated region 216591005083 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 216591005084 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591005085 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591005086 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591005087 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 2.5e-05 216591005088 PS00041 Bacterial regulatory proteins, araC family signature. 216591005089 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 1.9e-08 216591005090 Predicted helix-turn-helix motif with score 1320.000, SD 3.68 at aa 218-239, sequence VTLDEVAQAAGLSPFHAARLFT 216591005091 HMMPfam hit to PF02311, AraC-like ligand binding domain, score 1.8e-26 216591005092 Uncharacterized protein conserved in bacteria [Function unknown]; Region: CreA; COG3045 216591005093 CreA protein; Region: CreA; pfam05981 216591005094 HMMPfam hit to PF05981, CreA protein, score 2e-78 216591005095 Ferredoxin [Energy production and conversion]; Region: COG1146 216591005096 4Fe-4S binding domain; Region: Fer4; cl02805 216591005097 Domain of unknown function (DUF3470); Region: DUF3470; pfam11953 216591005098 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 1.1e-06 216591005099 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591005100 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0067 216591005101 nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514 216591005102 Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401 216591005103 active site 216591005104 HMMPfam hit to PF04095, Nicotinate phosphoribosyltransferase (NAPRTa, score 1.1e-106 216591005105 Uncharacterized conserved protein [Function unknown]; Region: COG1556 216591005106 HMMPfam hit to PF02589, Uncharacterized ACR, YkgG family COG1556, score 1.5e-08 216591005107 Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055 216591005108 Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221 216591005109 12 probable transmembrane helices predicted for BCAL0974 by TMHMM2.0 at aa 4-26, 33-55, 70-92, 99-116, 131-153, 166-188, 203-225, 258-280, 329-351, 372-394, 409-431 and 451-473 216591005110 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 216591005111 D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301 216591005112 dimerization interface [polypeptide binding]; other site 216591005113 ligand binding site [chemical binding]; other site 216591005114 NADP binding site [chemical binding]; other site 216591005115 catalytic site [active] 216591005116 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 1.7e-31 216591005117 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 2.1e-88 216591005118 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 216591005119 RmuC family; Region: RmuC; pfam02646 216591005120 HMMPfam hit to PF02646, RmuC family, score 7.9e-125 216591005121 putative acetyltransferase; Provisional; Region: PRK03624 216591005122 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591005123 Coenzyme A binding pocket [chemical binding]; other site 216591005124 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.7e-23 216591005125 2 probable transmembrane helices predicted for BCAL0978 by TMHMM2.0 at aa 16-38 and 48-70 216591005126 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005127 molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680 216591005128 MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887 216591005129 dimer interface [polypeptide binding]; other site 216591005130 putative functional site; other site 216591005131 putative MPT binding site; other site 216591005132 HMMPfam hit to PF03454, MoeA C-terminal region (domain IV), score 2e-16 216591005133 HMMPfam hit to PF00994, Probable molybdopterin binding domain, score 3.8e-42 216591005134 HMMPfam hit to PF03453, MoeA N-terminal region (domain I and II, score 9.6e-60 216591005135 molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317 216591005136 MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503 216591005137 GTP binding site; other site 216591005138 molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164 216591005139 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591005140 FeS/SAM binding site; other site 216591005141 Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463 216591005142 HMMPfam hit to PF06463, Molybdenum Cofactor Synthesis C, score 2.4e-43 216591005143 HMMPfam hit to PF04055, Radical SAM superfamily, score 3.1e-38 216591005144 PS01305 moaA / nifB / pqqE family signature. 216591005145 Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530 216591005146 S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453 216591005147 homodimer interface [polypeptide binding]; other site 216591005148 oligonucleotide binding site [chemical binding]; other site 216591005149 HMMPfam hit to PF00575, S1 RNA binding domain, score 2.3e-13 216591005150 23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025 216591005151 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940 216591005152 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 216591005153 active site 216591005154 HMMPfam hit to PF01479, S4 domain, score 1.6e-07 216591005155 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 1.9e-40 216591005156 PS01129 Rlu family of pseudouridine synthase signature. 216591005157 Predicted phosphatases [General function prediction only]; Region: Gph; COG0546 216591005158 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591005159 motif II; other site 216591005160 HAD-hyrolase-like; Region: Hydrolase_like; pfam13242 216591005161 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1e-30 216591005162 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467 216591005163 iron-sulfur cluster [ion binding]; other site 216591005164 [2Fe-2S] cluster binding site [ion binding]; other site 216591005165 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 1.5e-10 216591005166 Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023 216591005167 signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706 216591005168 tandem repeat interface [polypeptide binding]; other site 216591005169 oligomer interface [polypeptide binding]; other site 216591005170 active site residues [active] 216591005171 1 probable transmembrane helix predicted for BCAL0986 by TMHMM2.0 at aa 45-67 216591005172 HMMPfam hit to PF01343, Peptidase family S49, score 6.7e-39 216591005173 Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649 216591005174 putative SAM binding site [chemical binding]; other site 216591005175 homodimer interface [polypeptide binding]; other site 216591005176 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 2.3e-05 216591005177 Maf-like protein; Region: Maf; pfam02545 216591005178 Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555 216591005179 active site 216591005180 dimer interface [polypeptide binding]; other site 216591005181 HMMPfam hit to PF02545, Maf-like protein, score 1.3e-45 216591005182 Uncharacterized ACR, COG1399; Region: DUF177; pfam02620 216591005183 HMMPfam hit to PF02620, Uncharacterized ACR, COG1399, score 4.6e-19 216591005184 50S ribosomal protein L32; Validated; Region: rpmF; PRK01110 216591005185 HMMPfam hit to PF01783, Ribosomal L32p protein family, score 5e-19 216591005186 putative phosphate acyltransferase; Provisional; Region: PRK05331 216591005187 HMMPfam hit to PF02504, Fatty acid synthesis protein, score 2.5e-138 216591005188 PS00196 Type-1 copper (blue) proteins signature. 216591005189 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352 216591005190 Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830 216591005191 dimer interface [polypeptide binding]; other site 216591005192 active site 216591005193 CoA binding pocket [chemical binding]; other site 216591005194 HMMPfam hit to PF08545, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 7.8e-49 216591005195 HMMPfam hit to PF08541, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 3.1e-55 216591005196 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331 216591005197 malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128 216591005198 HMMPfam hit to PF00698, Acyl transferase domain, score 5.2e-11 216591005199 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005200 beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333 216591005201 3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830 216591005202 NAD(P) binding site [chemical binding]; other site 216591005203 homotetramer interface [polypeptide binding]; other site 216591005204 homodimer interface [polypeptide binding]; other site 216591005205 active site 216591005206 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.1e-36 216591005207 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0031 216591005208 PS00061 Short-chain dehydrogenases/reductases family signature. 216591005209 acyl carrier protein; Provisional; Region: acpP; PRK00982 216591005210 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.9e-22 216591005211 PS00012 Phosphopantetheine attachment site. 216591005212 3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314 216591005213 Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834 216591005214 dimer interface [polypeptide binding]; other site 216591005215 active site 216591005216 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 6.9e-82 216591005217 PS00017 ATP/GTP-binding site motif A (P-loop). 216591005218 PS00606 Beta-ketoacyl synthases active site. 216591005219 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 1.8e-60 216591005220 2 probable transmembrane helices predicted for BCAL0997 by TMHMM2.0 at aa 21-43 and 47-69 216591005221 RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939 216591005222 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591005223 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591005224 DNA binding residues [nucleotide binding] 216591005225 HMMPfam hit to PF04542, Sigma-70 region, score 2.9e-24 216591005226 PS01063 Sigma-70 factors ECF subfamily signature. 216591005227 HMMPfam hit to PF08281, Sigma-70, region, score 3.7e-20 216591005228 HMMPfam hit to PF04545, Sigma-70, region, score 2.4e-18 216591005229 Predicted helix-turn-helix motif with score 1461.000, SD 4.16 at aa 156-177, sequence LSYEEIAEMMGCPIGTVRSRIF 216591005230 Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872 216591005231 1 probable transmembrane helix predicted for BCAL0999 by TMHMM2.0 at aa 111-130 216591005232 anti-sigma E factor; Provisional; Region: rseB; PRK09455 216591005233 Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026 216591005234 HMMPfam hit to PF03888, MucB/RseB family, score 3.8e-28 216591005235 periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037 216591005236 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 216591005237 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 216591005238 protein binding site [polypeptide binding]; other site 216591005239 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 216591005240 protein binding site [polypeptide binding]; other site 216591005241 HMMPfam hit to PF00089, Trypsin, score 2.3e-16 216591005242 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 6.7e-08 216591005243 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 0.00082 216591005244 Glutaredoxin-like domain (DUF836); Region: DUF836; pfam05768 216591005245 HMMPfam hit to PF05768, Glutaredoxin-like domain (DUF836), score 7e-25 216591005246 GTP-binding protein LepA; Provisional; Region: PRK05433 216591005247 LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890 216591005248 G1 box; other site 216591005249 putative GEF interaction site [polypeptide binding]; other site 216591005250 GTP/Mg2+ binding site [chemical binding]; other site 216591005251 Switch I region; other site 216591005252 G2 box; other site 216591005253 G3 box; other site 216591005254 Switch II region; other site 216591005255 G4 box; other site 216591005256 G5 box; other site 216591005257 lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699 216591005258 lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709 216591005259 GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421 216591005260 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 4.7e-70 216591005261 PS00017 ATP/GTP-binding site motif A (P-loop). 216591005262 PS00301 GTP-binding elongation factors signature. 216591005263 HMMPfam hit to PF03144, Elongation factor Tu domain, score 3.7e-10 216591005264 HMMPfam hit to PF00679, Elongation factor G C-terminus, score 1.7e-35 216591005265 HMMPfam hit to PF06421, GTP-binding protein LepA C-terminus, score 2.2e-79 216591005266 signal peptidase I; Provisional; Region: PRK10861 216591005267 The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530 216591005268 Catalytic site [active] 216591005269 The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530 216591005270 2 probable transmembrane helices predicted for BCAL1004 by TMHMM2.0 at aa 4-26 and 72-94 216591005271 HMMPfam hit to PF00717, Peptidase S24-like, score 1.7e-26 216591005272 PS00501 Signal peptidases I serine active site. 216591005273 PS00760 Signal peptidases I lysine active site. 216591005274 PS00761 Signal peptidases I signature 3. 216591005275 ribonuclease III; Reviewed; Region: PRK12372 216591005276 RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593 216591005277 dimerization interface [polypeptide binding]; other site 216591005278 active site 216591005279 metal binding site [ion binding]; metal-binding site 216591005280 Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048 216591005281 HMMPfam hit to PF00636, RNase3 domain, score 5.8e-44 216591005282 PS00517 Ribonuclease III family signature. 216591005283 HMMPfam hit to PF00035, Double-stranded RNA binding motif, score 1.3e-14 216591005284 GTPase Era; Reviewed; Region: era; PRK00089 216591005285 E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163 216591005286 G1 box; other site 216591005287 GTP/Mg2+ binding site [chemical binding]; other site 216591005288 Switch I region; other site 216591005289 G2 box; other site 216591005290 Switch II region; other site 216591005291 G3 box; other site 216591005292 G4 box; other site 216591005293 G5 box; other site 216591005294 KH domain; Region: KH_2; pfam07650 216591005295 HMMPfam hit to PF01926, GTPase of unknown function, score 1.6e-38 216591005296 PS00017 ATP/GTP-binding site motif A (P-loop). 216591005297 HMMPfam hit to PF07650, KH domain, score 1e-25 216591005298 DNA repair protein RecO; Reviewed; Region: recO; PRK00085 216591005299 Recombination protein O N terminal; Region: RecO_N; pfam11967 216591005300 Recombination protein O C terminal; Region: RecO_C; pfam02565 216591005301 HMMPfam hit to PF02565, Recombination protein O, score 9.7e-21 216591005302 Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003 216591005303 active site 216591005304 hydrophilic channel; other site 216591005305 dimerization interface [polypeptide binding]; other site 216591005306 catalytic residues [active] 216591005307 active site lid [active] 216591005308 HMMPfam hit to PF03740, Pyridoxal phosphate biosynthesis protein Pdx, score 6.7e-138 216591005309 4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070 216591005310 HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase superfami, score 1.8e-10 216591005311 Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472 216591005312 beta-hexosaminidase; Provisional; Region: PRK05337 216591005313 HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N terminal, score 2.6e-32 216591005314 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591005315 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 216591005316 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591005317 active site 216591005318 phosphorylation site [posttranslational modification] 216591005319 intermolecular recognition site; other site 216591005320 dimerization interface [polypeptide binding]; other site 216591005321 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591005322 Walker A motif; other site 216591005323 ATP binding site [chemical binding]; other site 216591005324 Walker B motif; other site 216591005325 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591005326 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 1.6e-12 216591005327 Predicted helix-turn-helix motif with score 1795.000, SD 5.30 at aa 435-456, sequence GTRHRAATLLGISPKTLYNKLQ 216591005328 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 4.1e-69 216591005329 HMMPfam hit to PF00072, Response regulator receiver domain, score 7e-34 216591005330 elongation factor P; Validated; Region: PRK00529 216591005331 Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207 216591005332 S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470 216591005333 RNA binding site [nucleotide binding]; other site 216591005334 S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794 216591005335 RNA binding site [nucleotide binding]; other site 216591005336 HMMPfam hit to PF01132, Elongation factor P (EF-P) OB domain, score 2.4e-12 216591005337 HMMPfam hit to PF08207, Elongation factor P (EF-P) KOW-like domain, score 3.1e-05 216591005338 Uncharacterized protein conserved in bacteria (DUF2331); Region: DUF2331; pfam10093 216591005339 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4394 216591005340 CDS is interrupted by IS element insertion after codon 126. Similar to Burkholderia pseudomallei putative excinuclease ABC subunit C UniProt:Q63SA4 (EMBL:BX571965) (745 aa) fasta scores: E()=9e-108, 78.331% id in 743 aa 216591005341 HMMPfam hit to PF01541, GIY-YIG catalytic domain, score 3.9e-28 216591005342 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591005343 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591005344 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591005345 HMMPfam hit to PF01548, Transposase, score 2.9e-12 216591005346 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591005347 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005348 HMMPfam hit to PF02151, UvrB/uvrC motif, score 1.2e-07 216591005349 HMMPfam hit to PF08459, UvrC Helix-hairpin-helix N-terminal, score 6.3e-78 216591005350 CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453 216591005351 5 probable transmembrane helices predicted for BCAL1019 by TMHMM2.0 at aa 5-27, 34-53, 80-102, 135-157 and 161-180 216591005352 HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 6.3e-39 216591005353 PS00379 CDP-alcohol phosphatidyltransferases signature. 216591005354 Cache domain; Region: Cache_1; pfam02743 216591005355 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591005356 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591005357 metal binding site [ion binding]; metal-binding site 216591005358 active site 216591005359 I-site; other site 216591005360 2 probable transmembrane helices predicted for BCAL1020 by TMHMM2.0 at aa 6-28 and 288-310 216591005361 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005362 HMMPfam hit to PF00990, GGDEF domain, score 5.9e-75 216591005363 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591005364 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 2.5e-06 216591005365 Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247 216591005366 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.6e-15 216591005367 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591005368 sequence-specific DNA binding site [nucleotide binding]; other site 216591005369 salt bridge; other site 216591005370 Cupin domain; Region: Cupin_2; cl17218 216591005371 HMMPfam hit to PF07883, Cupin domain, score 0.0031 216591005372 HMMPfam hit to PF01381, Helix-turn-helix, score 2.6e-11 216591005373 Predicted helix-turn-helix motif with score 1253.000, SD 3.45 at aa 31-52, sequence YTLDTLAARSGVSRSMISLIER 216591005374 Protein of unknown function (DUF3423); Region: DUF3423; pfam11903 216591005375 Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086 216591005376 active site 216591005377 HMMPfam hit to PF00557, metallopeptidase family M24, score 1.1e-84 216591005378 PS00215 Mitochondrial energy transfer proteins signature. 216591005379 PS00680 Methionine aminopeptidase subfamily 1 signature. 216591005380 GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956 216591005381 PS01320 Uncharacterized protein family UPF0067 signature. 216591005382 Similar to Anabaena sp. putative transposase SWALL:O68472 (EMBL:AF047044) (320 aa) fasta scores: E(): 2.9e-36, 40.83% id in 311 aa. CDS contains nonsense mutation (amber) after codon 62 and a frameshift mutation after codon 137 216591005383 HMMPfam hit to PF01548, Transposase, score 4.7e-12 216591005384 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591005385 LysR family transcriptional regulator; Provisional; Region: PRK14997 216591005386 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591005387 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473 216591005388 putative effector binding pocket; other site 216591005389 putative dimerization interface [polypeptide binding]; other site 216591005390 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.5e-38 216591005391 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005392 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1e-15 216591005393 Pirin-related protein [General function prediction only]; Region: COG1741 216591005394 Pirin; Region: Pirin; pfam02678 216591005395 Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726 216591005396 HMMPfam hit to PF02678, Pirin, score 5.8e-54 216591005397 HMMPfam hit to PF05726, Pirin C-terminal cupin domain, score 4e-43 216591005398 RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169 216591005399 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591005400 Coenzyme A binding pocket [chemical binding]; other site 216591005401 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.2e-07 216591005402 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678 216591005403 7 probable transmembrane helices predicted for BCAL1032 by TMHMM2.0 at aa 10-29, 42-61, 76-98, 127-149, 153-175, 188-210 and 236-258 216591005404 Protein of unknown function (DUF461); Region: DUF461; pfam04314 216591005405 HMMPfam hit to PF04314, Protein of unknown function (DUF461), score 1.1e-30 216591005406 1 probable transmembrane helix predicted for BCAL1033 by TMHMM2.0 at aa 12-34 216591005407 SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968 216591005408 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999 216591005409 Cu(I) binding site [ion binding]; other site 216591005410 HMMPfam hit to PF02630, SCO1/SenC, score 3.2e-24 216591005411 trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105 216591005412 Trehalose-phosphatase; Region: Trehalose_PPase; pfam02358 216591005413 HMMPfam hit to PF02358, Trehalose-phosphatase, score 5.2e-63 216591005414 Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788 216591005415 alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400 216591005416 active site 216591005417 homotetramer interface [polypeptide binding]; other site 216591005418 HMMPfam hit to PF00982, Glycosyltransferase family, score 8.1e-157 216591005419 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591005420 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591005421 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591005422 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591005423 Predicted helix-turn-helix motif with score 1703.000, SD 4.99 at aa 20-41, sequence EAIRAVARTHGLSHSTVSQWYA 216591005424 putative transposase OrfB; Reviewed; Region: PHA02517 216591005425 HTH-like domain; Region: HTH_21; pfam13276 216591005426 Integrase core domain; Region: rve; pfam00665 216591005427 Integrase core domain; Region: rve_2; pfam13333 216591005428 HMMPfam hit to PF00665, Integrase core domain, score 5.1e-42 216591005429 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 216591005430 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 216591005431 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591005432 Walker A/P-loop; other site 216591005433 ATP binding site [chemical binding]; other site 216591005434 Q-loop/lid; other site 216591005435 ABC transporter signature motif; other site 216591005436 Walker B; other site 216591005437 D-loop; other site 216591005438 H-loop/switch region; other site 216591005439 HMMPfam hit to PF00005, ABC transporter, score 2e-65 216591005440 PS00211 ABC transporters family signature. 216591005441 PS00017 ATP/GTP-binding site motif A (P-loop). 216591005442 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 2.2e-05 216591005443 5 probable transmembrane helices predicted for BCAL1039 by TMHMM2.0 at aa 37-59, 74-96, 155-174, 178-195 and 263-285 216591005444 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005445 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005446 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591005447 This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802 216591005448 putative ADP-binding pocket [chemical binding]; other site 216591005449 HMMPfam hit to PF00534, Glycosyl transferases group, score 9.1e-23 216591005450 4 probable transmembrane helices predicted for BCAL1041 by TMHMM2.0 at aa 12-34, 49-71, 91-113 and 118-140 216591005451 Predicted membrane protein (DUF2214); Region: DUF2214; pfam09980 216591005452 4 probable transmembrane helices predicted for BCAL1042 by TMHMM2.0 at aa 5-24, 49-68, 88-107 and 128-150 216591005453 glucarate dehydratase; Region: glucar-dehydr; TIGR03247 216591005454 D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323 216591005455 active site 216591005456 tetramer interface [polypeptide binding]; other site 216591005457 PS00294 Prenyl group binding site (CAAX box). 216591005458 HMMPfam hit to PF01188, Mandelate racemase / muconate lactonizing en, score 7.6e-06 216591005459 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591005460 phosphonate utilization associated transcriptional regulator; Region: phnR_burk; TIGR03338 216591005461 DNA-binding site [nucleotide binding]; DNA binding site 216591005462 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 216591005463 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 5.5e-23 216591005464 HMMPfam hit to PF07729, FCD domain, score 6.7e-39 216591005465 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591005466 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 216591005467 dimerization interface [polypeptide binding]; other site 216591005468 ligand binding site [chemical binding]; other site 216591005469 HMMPfam hit to PF01094, Receptor family ligand binding region, score 7e-46 216591005470 phospholipase C, phosphocholine-specific, Pseudomonas-type; Region: PC_PLC; TIGR03396 216591005471 Phosphoesterase family; Region: Phosphoesterase; pfam04185 216591005472 Domain of unknown function (DUF756); Region: DUF756; pfam05506 216591005473 Domain of unknown function (DUF756); Region: DUF756; pfam05506 216591005474 HMMPfam hit to PF05506, Domain of unknown function (DUF756), score 3.2e-29 216591005475 HMMPfam hit to PF05506, Domain of unknown function (DUF756), score 2.1e-38 216591005476 HMMPfam hit to PF04185, Phosphoesterase family, score 1e-190 216591005477 pyridoxamine kinase; Validated; Region: PRK05756 216591005478 Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate (PLP), by catalyzing the phosphorylation of the precursor vitamin B6 in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173 216591005479 dimer interface [polypeptide binding]; other site 216591005480 pyridoxal binding site [chemical binding]; other site 216591005481 ATP binding site [chemical binding]; other site 216591005482 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591005483 Alpha/beta hydrolase of unknown function (DUF1057); Region: DUF1057; pfam06342 216591005484 1 probable transmembrane helix predicted for BCAL1048 by TMHMM2.0 at aa 13-35 216591005485 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005486 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.3e-18 216591005487 luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558 216591005488 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892 216591005489 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347 216591005490 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 3.3e-22 216591005491 Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis; Region: Glucosylceramide_synthase; cd02520 216591005492 ligand binding site; other site 216591005493 Glycosyl transferase family 21; Region: Glyco_transf_21; pfam13506 216591005494 3 probable transmembrane helices predicted for BCAL1050 by TMHMM2.0 at aa 10-32, 283-305 and 309-331 216591005495 HMMPfam hit to PF00535, Glycosyl transferase family, score 2e-06 216591005496 hopanoid biosynthesis associated radical SAM protein HpnJ; Region: HpnJ; TIGR03471 216591005497 B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293 216591005498 B12 binding site [chemical binding]; other site 216591005499 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591005500 FeS/SAM binding site; other site 216591005501 HMMPfam hit to PF04055, Radical SAM superfamily, score 7.9e-22 216591005502 hopanoid biosynthesis associated protein HpnK and similar proteins; Region: YdjC_HpnK_like; cd10804 216591005503 putative active site [active] 216591005504 YdjC motif; other site 216591005505 Mg binding site [ion binding]; other site 216591005506 putative homodimer interface [polypeptide binding]; other site 216591005507 HMMPfam hit to PF04794, YdjC-like protein, score 7.8e-21 216591005508 Uncharacterized protein family (UPF0104); Region: UPF0104; cl04219 216591005509 5 probable transmembrane helices predicted for BCAL1053 by TMHMM2.0 at aa 7-26, 36-58, 116-138, 143-165 and 211-233 216591005510 SmpA / OmlA family; Region: SmpA_OmlA; cl17115 216591005511 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005512 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591005513 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591005514 dimer interface [polypeptide binding]; other site 216591005515 conserved gate region; other site 216591005516 putative PBP binding loops; other site 216591005517 ABC-ATPase subunit interface; other site 216591005518 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6.3e-31 216591005519 5 probable transmembrane helices predicted for BCAL1055 by TMHMM2.0 at aa 15-37, 56-78, 93-110, 150-172 and 192-214 216591005520 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591005521 PS00017 ATP/GTP-binding site motif A (P-loop). 216591005522 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591005523 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591005524 dimer interface [polypeptide binding]; other site 216591005525 conserved gate region; other site 216591005526 putative PBP binding loops; other site 216591005527 ABC-ATPase subunit interface; other site 216591005528 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.8e-23 216591005529 5 probable transmembrane helices predicted for BCAL1056 by TMHMM2.0 at aa 20-42, 63-85, 105-127, 160-182 and 197-219 216591005530 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591005531 Predicted helix-turn-helix motif with score 1141.000, SD 3.07 at aa 130-151, sequence HGEVEAARAYGMSPFTMYRRVI 216591005532 ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; Region: HisP; COG4598 216591005533 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 216591005534 Walker A/P-loop; other site 216591005535 ATP binding site [chemical binding]; other site 216591005536 Q-loop/lid; other site 216591005537 ABC transporter signature motif; other site 216591005538 Walker B; other site 216591005539 D-loop; other site 216591005540 H-loop/switch region; other site 216591005541 HMMPfam hit to PF00005, ABC transporter, score 1.5e-67 216591005542 PS00017 ATP/GTP-binding site motif A (P-loop). 216591005543 PS00211 ABC transporters family signature. 216591005544 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591005545 AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136 216591005546 conserved cys residue [active] 216591005547 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591005548 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591005549 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1e-07 216591005550 Predicted helix-turn-helix motif with score 1646.000, SD 4.79 at aa 236-257, sequence LTTDEIAGLVGVSRRQLERLFR 216591005551 PS00041 Bacterial regulatory proteins, araC family signature. 216591005552 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 9.4e-11 216591005553 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093 216591005554 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591005555 inhibitor-cofactor binding pocket; inhibition site 216591005556 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591005557 catalytic residue [active] 216591005558 HMMPfam hit to PF00202, Aminotransferase class-III, score 1e-146 216591005559 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591005560 Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138 216591005561 Arginine N-succinyltransferase beta subunit; Region: AstA; cl11440 216591005562 HMMPfam hit to PF04958, Arginine N-succinyltransferase beta subunit, score 2.4e-105 216591005563 Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138 216591005564 arginine N-succinyltransferase; Region: arg_catab_AstA; TIGR03244 216591005565 HMMPfam hit to PF04958, Arginine N-succinyltransferase beta subunit, score 4.9e-161 216591005566 succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457 216591005567 N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095 216591005568 NAD(P) binding site [chemical binding]; other site 216591005569 catalytic residues [active] 216591005570 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 9.6e-128 216591005571 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591005572 PS00070 Aldehyde dehydrogenases cysteine active site. 216591005573 succinylarginine dihydrolase; Provisional; Region: PRK13281 216591005574 HMMPfam hit to PF04996, Succinylarginine dihydrolase, score 1.1e-268 216591005575 succinylglutamate desuccinylase; Provisional; Region: PRK05324 216591005576 Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952 216591005577 active site 216591005578 Zn binding site [ion binding]; other site 216591005579 HMMPfam hit to PF04952, Succinylglutamate desuccinylase / Aspartoac, score 1.3e-69 216591005580 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591005581 lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096 216591005582 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591005583 substrate binding pocket [chemical binding]; other site 216591005584 membrane-bound complex binding site; other site 216591005585 hinge residues; other site 216591005586 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.7e-89 216591005587 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591005588 putative transposase OrfB; Reviewed; Region: PHA02517 216591005589 HTH-like domain; Region: HTH_21; pfam13276 216591005590 Integrase core domain; Region: rve; pfam00665 216591005591 Integrase core domain; Region: rve_2; pfam13333 216591005592 HMMPfam hit to PF00665, Integrase core domain, score 3.8e-47 216591005593 Predicted helix-turn-helix motif with score 1108.000, SD 2.96 at aa 8-29, sequence HPVAALLKAAGLARSTFYYQLK 216591005594 PS00228 Tubulin-beta mRNA autoregulation signal. 216591005595 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591005596 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591005597 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591005598 HMMPfam hit to PF02178, AT hook motif, score 0.016 216591005599 HMMPfam hit to PF01527, Transposase, score 0.0012 216591005600 Predicted helix-turn-helix motif with score 1296.000, SD 3.60 at aa 21-42, sequence AGTKTLAHRYGVGRTMVRRWVA 216591005601 HDOD domain; Region: HDOD; pfam08668 216591005602 PAS domain; Region: PAS_9; pfam13426 216591005603 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591005604 putative active site [active] 216591005605 heme pocket [chemical binding]; other site 216591005606 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591005607 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591005608 metal binding site [ion binding]; metal-binding site 216591005609 active site 216591005610 I-site; other site 216591005611 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 216591005612 HMMPfam hit to PF00563, EAL domain, score 3.9e-116 216591005613 HMMPfam hit to PF00990, GGDEF domain, score 8.1e-33 216591005614 HMMPfam hit to PF08448, PAS fold, score 0.0044 216591005615 Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017 216591005616 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591005617 catalytic triad [active] 216591005618 HMMPfam hit to PF08534, Redoxin, score 2.4e-17 216591005619 HMMPfam hit to PF00578, AhpC/TSA family, score 1.7e-10 216591005620 atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243 216591005621 NADH(P)-binding; Region: NAD_binding_10; pfam13460 216591005622 NAD(P) binding site [chemical binding]; other site 216591005623 putative active site [active] 216591005624 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 8.8e-05 216591005625 NYN domain; Region: NYN; pfam01936 216591005626 putative metal binding site [ion binding]; other site 216591005627 Uncharacterized conserved protein [Function unknown]; Region: COG1432 216591005628 C-terminal domain of LabA_like proteins; Region: LabA_like_C; cd10146 216591005629 HMMPfam hit to PF01936, Protein of unknown function DUF88, score 3.4e-11 216591005630 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 216591005631 active site 216591005632 metal binding site [ion binding]; metal-binding site 216591005633 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 3.8e-05 216591005634 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080 216591005635 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591005636 catalytic loop [active] 216591005637 iron binding site [ion binding]; other site 216591005638 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 216591005639 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 6.9e-12 216591005640 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591005641 HMMPfam hit to PF01799, [2Fe-2S] binding domain, score 1.7e-32 216591005642 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 216591005643 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591005644 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591005645 1 probable transmembrane helix predicted for BCAL1075 by TMHMM2.0 at aa 13-35 216591005646 HMMPfam hit to PF02738, Aldehyde oxidase and xanthine dehydroge, score 1.2e-08 216591005647 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591005648 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591005649 eyelet of channel; other site 216591005650 trimer interface [polypeptide binding]; other site 216591005651 PS00572 Glycosyl hydrolases family 1 active site. 216591005652 Cupin; Region: Cupin_6; pfam12852 216591005653 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591005654 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591005655 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591005656 PS00041 Bacterial regulatory proteins, araC family signature. 216591005657 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1e-06 216591005658 Predicted helix-turn-helix motif with score 1288.000, SD 3.57 at aa 225-246, sequence WQLASLAAEAGMSRSRFCAHFA 216591005659 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 5.5e-06 216591005660 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 216591005661 multidrug efflux system subunit MdtC; Provisional; Region: PRK10614 216591005662 Protein export membrane protein; Region: SecD_SecF; cl14618 216591005663 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 216591005664 10 probable transmembrane helices predicted for BCAL1079 by TMHMM2.0 at aa 7-29, 336-353, 360-382, 434-456, 463-485, 527-549, 922-944, 964-986, 1017-1039 and 1054-1076 216591005665 multidrug efflux system subunit MdtB; Provisional; Region: PRK10503 216591005666 Protein export membrane protein; Region: SecD_SecF; cl14618 216591005667 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 216591005668 10 probable transmembrane helices predicted for BCAL1080 by TMHMM2.0 at aa 7-29, 334-353, 360-382, 431-453, 460-482, 529-548, 858-880, 900-922, 953-975 and 990-1012 216591005669 PS00152 ATP synthase alpha and beta subunits signature. 216591005670 multidrug efflux system subunit MdtA; Provisional; Region: PRK11556 216591005671 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591005672 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591005673 HMMPfam hit to PF00529, HlyD family secretion protein, score 6.2e-24 216591005674 1 probable transmembrane helix predicted for BCAL1081 by TMHMM2.0 at aa 26-45 216591005675 CDS contains a nonsense mutation (ochre) after codon 46. Similar to Burkholderia cenocepacia HI2424 IclR family regulatory protein UniProt:Q4LT17 (EMBL:AAHL01000018) (274 aa) fasta scores: E()=1.6e-96, 97.080% id in 274 aa 216591005676 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 9e-06 216591005677 Bacterial protein of unknown function (DUF839); Region: DUF839; pfam05787 216591005678 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005679 Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004 216591005680 HMMPfam hit to PF00909, Ammonium Transporter Family, score 5.6e-88 216591005681 9 probable transmembrane helices predicted for BCAL1084 by TMHMM2.0 at aa 10-32, 44-66, 86-108, 115-137, 157-179, 227-249, 278-300, 307-329 and 344-366 216591005682 PS01219 Ammonium transporters signature. 216591005683 3 probable transmembrane helices predicted for BCAL1085 by TMHMM2.0 at aa 4-23, 43-65 and 75-97 216591005684 1 probable transmembrane helix predicted for BCAL1086 by TMHMM2.0 at aa 13-30 216591005685 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005686 Predicted transcriptional regulator [Transcription]; Region: COG1959 216591005687 Transcriptional regulator; Region: Rrf2; pfam02082 216591005688 HMMPfam hit to PF02082, Transcriptional regulator, score 7.5e-42 216591005689 biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244 216591005690 NADH(P)-binding; Region: NAD_binding_10; pfam13460 216591005691 NAD binding site [chemical binding]; other site 216591005692 putative active site [active] 216591005693 substrate binding site [chemical binding]; other site 216591005694 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 7e-05 216591005695 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591005696 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591005697 putative DNA binding site [nucleotide binding]; other site 216591005698 putative Zn2+ binding site [ion binding]; other site 216591005699 AsnC family; Region: AsnC_trans_reg; pfam01037 216591005700 Predicted helix-turn-helix motif with score 1415.000, SD 4.01 at aa 18-39, sequence LPIAELAQRVNLSQTPCWKRVQ 216591005701 PS00519 Bacterial regulatory proteins, asnC family signature. 216591005702 HMMPfam hit to PF01037, AsnC family, score 2.8e-28 216591005703 ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259 216591005704 sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968 216591005705 Walker A/P-loop; other site 216591005706 ATP binding site [chemical binding]; other site 216591005707 Q-loop/lid; other site 216591005708 ABC transporter signature motif; other site 216591005709 Walker B; other site 216591005710 D-loop; other site 216591005711 H-loop/switch region; other site 216591005712 HMMPfam hit to PF00005, ABC transporter, score 1.4e-57 216591005713 PS00211 ABC transporters family signature. 216591005714 PS00017 ATP/GTP-binding site motif A (P-loop). 216591005715 ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178 216591005716 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591005717 dimer interface [polypeptide binding]; other site 216591005718 conserved gate region; other site 216591005719 putative PBP binding loops; other site 216591005720 ABC-ATPase subunit interface; other site 216591005721 ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178 216591005722 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591005723 dimer interface [polypeptide binding]; other site 216591005724 conserved gate region; other site 216591005725 putative PBP binding loops; other site 216591005726 ABC-ATPase subunit interface; other site 216591005727 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.0031 216591005728 12 probable transmembrane helices predicted for BCAL1091 by TMHMM2.0 at aa 32-54, 78-100, 107-129, 164-186, 206-228, 260-282, 303-325, 352-374, 395-417, 432-451, 487-506 and 539-558 216591005729 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005730 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 8.8e-19 216591005731 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591005732 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005733 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 216591005734 Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416 216591005735 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 2.2e-12 216591005736 1 probable transmembrane helix predicted for BCAL1093 by TMHMM2.0 at aa 12-34 216591005737 putative proline-specific permease; Provisional; Region: proY; PRK10580 216591005738 Spore germination protein; Region: Spore_permease; cl17796 216591005739 HMMPfam hit to PF00324, Amino acid permease, score 6e-127 216591005740 12 probable transmembrane helices predicted for BCAL1094 by TMHMM2.0 at aa 12-29, 33-55, 93-115, 120-142, 154-176, 196-218, 239-261, 281-303, 329-351, 355-377, 398-420 and 424-446 216591005741 PS00218 Amino acid permeases signature. 216591005742 integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667 216591005743 FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805 216591005744 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 216591005745 HMMPfam hit to PF05976, Bacterial membrane protein of unknown functi, score 4.4e-48 216591005746 8 probable transmembrane helices predicted for BCAL1095 by TMHMM2.0 at aa 15-37, 69-86, 90-112, 133-155, 408-430, 451-468, 483-505 and 518-540 216591005747 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005748 exonuclease V subunit gamma; Provisional; Region: recC; PRK11069 216591005749 Exodeoxyribonuclease V, gamma subunit; Region: Exonuc_V_gamma; pfam04257 216591005750 HMMPfam hit to PF04257, Exodeoxyribonuclease V, gamma subunit, score 2e-168 216591005751 UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580 216591005752 UvrD-like helicase C-terminal domain; Region: UvrD_C; pfam13361 216591005753 Family description; Region: UvrD_C_2; pfam13538 216591005754 PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705 216591005755 HMMPfam hit to PF00580, UvrD/REP helicase, score 1.6e-44 216591005756 PS00017 ATP/GTP-binding site motif A (P-loop). 216591005757 AAA domain; Region: AAA_30; pfam13604 216591005758 Family description; Region: UvrD_C_2; pfam13538 216591005759 PS00017 ATP/GTP-binding site motif A (P-loop). 216591005760 hypothetical protein; Provisional; Region: PRK09256 216591005761 Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186 216591005762 HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 2e-26 216591005763 PS00745 Prokaryotic-type class I peptide chain release factors signature. 216591005764 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 216591005765 HMMPfam hit to PF00563, EAL domain, score 4.8e-28 216591005766 EamA-like transporter family; Region: EamA; pfam00892 216591005767 Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950 216591005768 EamA-like transporter family; Region: EamA; pfam00892 216591005769 10 probable transmembrane helices predicted for BCAL1101 by TMHMM2.0 at aa 5-27, 32-54, 67-89, 94-116, 123-145, 155-174, 187-209, 219-241, 248-267 and 272-294 216591005770 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.6e-20 216591005771 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005772 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 3.4e-17 216591005773 2 probable transmembrane helices predicted for BCAL1102 by TMHMM2.0 at aa 27-46 and 76-98 216591005774 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005775 1 probable transmembrane helix predicted for BCAL1103 by TMHMM2.0 at aa 34-56 216591005776 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005777 thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284 216591005778 ThiC-associated domain; Region: ThiC-associated; pfam13667 216591005779 Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422 216591005780 HMMPfam hit to PF01964, ThiC family, score 0 216591005781 1 probable transmembrane helix predicted for BCAL1105 by TMHMM2.0 at aa 4-22 216591005782 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117 216591005783 Cytochrome b(N-terminal)/b6/petB; Region: Cytochrom_B_N; pfam00033 216591005784 HMMPfam hit to PF01292, Cytochrome b561 family, score 0.0032 216591005785 4 probable transmembrane helices predicted for BCAL1106 by TMHMM2.0 at aa 29-46, 70-92, 137-156 and 176-198 216591005786 Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041 216591005787 Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199 216591005788 Moco binding site; other site 216591005789 metal coordination site [ion binding]; other site 216591005790 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005791 HMMPfam hit to PF00174, Oxidoreductase molybdopterin binding d, score 5.8e-63 216591005792 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591005793 non-specific DNA binding site [nucleotide binding]; other site 216591005794 salt bridge; other site 216591005795 sequence-specific DNA binding site [nucleotide binding]; other site 216591005796 HMMPfam hit to PF01381, Helix-turn-helix, score 1.5e-06 216591005797 Predicted helix-turn-helix motif with score 2019.000, SD 6.06 at aa 42-63, sequence LSQAEAAKQLGVTQPRVSDLMR 216591005798 Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470 216591005799 HMMPfam hit to PF05973, Phage derived protein Gp49-like (DUF891), score 5.5e-18 216591005800 putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272 216591005801 10 probable transmembrane helices predicted for BCAL1110 by TMHMM2.0 at aa 32-49, 59-81, 93-115, 119-141, 148-170, 174-191, 204-226, 236-258, 265-287 and 292-311 216591005802 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 8.9e-14 216591005803 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 6.3e-14 216591005804 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591005805 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591005806 12 probable transmembrane helices predicted for BCAL1111 by TMHMM2.0 at aa 35-57, 72-94, 101-120, 124-146, 159-181, 185-207, 241-263, 273-295, 302-320, 324-341, 361-383 and 387-406 216591005807 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.6e-33 216591005808 Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402 216591005809 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 216591005810 active site 216591005811 metal binding site [ion binding]; metal-binding site 216591005812 hexamer interface [polypeptide binding]; other site 216591005813 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 4.6e-15 216591005814 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 216591005815 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591005816 Walker A/P-loop; other site 216591005817 ATP binding site [chemical binding]; other site 216591005818 Q-loop/lid; other site 216591005819 ABC transporter signature motif; other site 216591005820 Walker B; other site 216591005821 D-loop; other site 216591005822 H-loop/switch region; other site 216591005823 TOBE domain; Region: TOBE_2; pfam08402 216591005824 HMMPfam hit to PF08402, TOBE domain, score 8.3e-08 216591005825 HMMPfam hit to PF00005, ABC transporter, score 3e-62 216591005826 PS00211 ABC transporters family signature. 216591005827 PS00148 Arginase family signature 2. 216591005828 PS00017 ATP/GTP-binding site motif A (P-loop). 216591005829 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 216591005830 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591005831 dimer interface [polypeptide binding]; other site 216591005832 conserved gate region; other site 216591005833 putative PBP binding loops; other site 216591005834 ABC-ATPase subunit interface; other site 216591005835 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.0006 216591005836 6 probable transmembrane helices predicted for BCAL1114 by TMHMM2.0 at aa 21-43, 78-100, 113-135, 141-163, 200-222 and 247-269 216591005837 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591005838 dimer interface [polypeptide binding]; other site 216591005839 conserved gate region; other site 216591005840 ABC-ATPase subunit interface; other site 216591005841 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.1e-15 216591005842 6 probable transmembrane helices predicted for BCAL1115 by TMHMM2.0 at aa 12-34, 63-85, 94-116, 136-158, 198-220 and 240-262 216591005843 PS00041 Bacterial regulatory proteins, araC family signature. 216591005844 Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416 216591005845 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 216591005846 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 0.00085 216591005847 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591005848 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591005849 DNA binding site [nucleotide binding] 216591005850 domain linker motif; other site 216591005851 Ligand-binding domain of putative DNA transcription repressors highly similar to that of the repressor specific for gluconate (GntR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR_like_2; cd06282 216591005852 putative dimerization interface [polypeptide binding]; other site 216591005853 putative ligand binding site [chemical binding]; other site 216591005854 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 2.2e-23 216591005855 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 9.7e-08 216591005856 Predicted helix-turn-helix motif with score 1753.000, SD 5.16 at aa 3-24, sequence STIKDVAALAGFSIATVSRAIN 216591005857 BcenGI5 216591005858 integrase; Provisional; Region: PRK09692 216591005859 Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801 216591005860 active site 216591005861 Int/Topo IB signature motif; other site 216591005862 HMMPfam hit to PF00589, Phage integrase family, score 4e-10 216591005863 Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523 216591005864 Protein of unknown function (DUF3987); Region: DUF3987; pfam13148 216591005865 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005866 Protein of unknown function (DUF3296); Region: DUF3296; pfam11726 216591005867 CDS is interrupted by IS element insertion after codon 261. Similar to Escherichia coli O157:H7 hypothetical protein UniProt:Q8X405 (EMBL:AE005174) (302 aa) fasta scores: E()=0.0016, 25.987% id in 304 aa 216591005868 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 216591005869 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 216591005870 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 216591005871 Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586 216591005872 HMMPfam hit to PF01609, Transposase DDE domain, score 3.6e-32 216591005873 Domain of unknown function (DUF955); Region: DUF955; pfam06114 216591005874 HMMPfam hit to PF06114, Domain of unknown function (DUF955), score 1.6e-14 216591005875 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591005876 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591005877 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591005878 non-specific DNA binding site [nucleotide binding]; other site 216591005879 salt bridge; other site 216591005880 sequence-specific DNA binding site [nucleotide binding]; other site 216591005881 HMMPfam hit to PF01381, Helix-turn-helix, score 6.5e-10 216591005882 Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400 216591005883 active site 216591005884 NTP binding site [chemical binding]; other site 216591005885 metal binding triad [ion binding]; metal-binding site 216591005886 CDS interrupted by IS element insertion after codon 94. Similar to Lactococcus lactis hypothetical protein ORF00028 UniProt:O87230 (EMBL:AE001272) (252 aa) fasta scores: E()=5.7e-13, 27.888% id in 251 aa 216591005887 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 216591005888 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 216591005889 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 216591005890 Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586 216591005891 HMMPfam hit to PF01609, Transposase DDE domain, score 3.6e-32 216591005892 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding [General function prediction only]; Region: COG5516 216591005893 Protein of unknown function (DUF1470); Region: DUF1470; pfam07336 216591005894 CGNR zinc finger; Region: zf-CGNR; pfam11706 216591005895 HMMPfam hit to PF07336, Protein of unknown function (DUF1470), score 1.4e-41 216591005896 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591005897 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591005898 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 2.2e-21 216591005899 Probable gene remnant. CDS is truncated by the insertion of the upstream IS element and lacks an appropriate translational start site. Similar to the C-terminal region of Burkholderia vietnamiensis G4 helix-turn-helix, AraC type protein UniProt:Q4BC89 (EMBL:AAEH02000043) (316 aa) fasta scores: E()=8.2e-34, 38.796% id in 299 aa 216591005900 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.1e-06 216591005901 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00039 216591005902 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 216591005903 DNA-binding interface [nucleotide binding]; DNA binding site 216591005904 HMMPfam hit to PF01527, Transposase, score 8.2e-25 216591005905 Predicted helix-turn-helix motif with score 1325.000, SD 3.70 at aa 22-43, sequence TPVAEVCRKMGISDATFYNWRT 216591005906 putative transposase OrfB; Reviewed; Region: PHA02517 216591005907 HTH-like domain; Region: HTH_21; pfam13276 216591005908 Integrase core domain; Region: rve; pfam00665 216591005909 Integrase core domain; Region: rve_3; pfam13683 216591005910 HMMPfam hit to PF00665, Integrase core domain, score 9.5e-40 216591005911 C-terminus is similar to Ralstonia solanacearum ISRso17-transposase protein SWALL:Q8XF94 (EMBL:AL646078) (443 aa) fasta scores: E(): 6.4e-23, 65.65% id in 99 aa 216591005912 Probable gene remnant. Similar to the C-tyerminal region of Burkholderia pseudomallei putative dehydrogenase UniProt:Q63VC6 (EMBL:BX571965) (256 aa) fasta scores: E()=1.5e-08, 74.359% id in 39 aa 216591005913 Domain of unknown function (DUF4105); Region: DUF4105; pfam13387 216591005914 6 probable transmembrane helices predicted for BCAL1145 by TMHMM2.0 at aa 13-35, 45-67, 74-93, 97-119, 126-145 and 149-171 216591005915 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591005916 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591005917 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591005918 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.2e-10 216591005919 PS00041 Bacterial regulatory proteins, araC family signature. 216591005920 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.0018 216591005921 Predicted helix-turn-helix motif with score 1220.000, SD 3.34 at aa 364-385, sequence IGLADLARLAGLSEHATIAAFK 216591005922 PS00041 Bacterial regulatory proteins, araC family signature. 216591005923 Predicted helix-turn-helix motif with score 1220.000, SD 3.34 at aa 246-267, sequence KTLGSIAHALGCPTGALDNAIR 216591005924 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591005925 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 216591005926 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005927 HMMPfam hit to PF00534, Glycosyl transferases group, score 2.7e-24 216591005928 Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726 216591005929 Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918 216591005930 putative active site [active] 216591005931 putative metal binding site [ion binding]; other site 216591005932 HMMPfam hit to PF01522, Polysaccharide deacetylase, score 5.4e-36 216591005933 Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364 216591005934 13 probable transmembrane helices predicted for BCAL1149 by TMHMM2.0 at aa 29-46, 107-129, 136-155, 165-184, 196-218, 238-260, 267-289, 299-321, 328-347, 352-369, 382-404, 424-446 and 458-480 216591005935 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591005936 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591005937 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 9.5e-05 216591005938 Predicted helix-turn-helix motif with score 1716.000, SD 5.03 at aa 239-260, sequence LTLAEIAEAADCSIRSLSRAFS 216591005939 PS00041 Bacterial regulatory proteins, araC family signature. 216591005940 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 7.7e-08 216591005941 classical (c) SDRs; Region: SDR_c; cd05233 216591005942 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557 216591005943 NAD(P) binding site [chemical binding]; other site 216591005944 active site 216591005945 HMMPfam hit to PF00106, short chain dehydrogenase, score 4.4e-30 216591005946 Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768 216591005947 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 216591005948 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591005949 NAD(P) binding site [chemical binding]; other site 216591005950 catalytic residues [active] 216591005951 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.1e-223 216591005952 PS00070 Aldehyde dehydrogenases cysteine active site. 216591005953 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591005954 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591005955 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591005956 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591005957 trimer interface [polypeptide binding]; other site 216591005958 eyelet of channel; other site 216591005959 Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518 216591005960 HMMPfam hit to PF01177, Asp/Glu/Hydantoin racemase, score 1.5e-26 216591005961 benzoate transport; Region: 2A0115; TIGR00895 216591005962 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591005963 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591005964 12 probable transmembrane helices predicted for BCAL1156 by TMHMM2.0 at aa 23-45, 60-82, 89-111, 115-137, 150-172, 176-198, 261-283, 293-315, 320-342, 352-374, 387-409 and 414-436 216591005965 HMMPfam hit to PF00083, Sugar (and other) transporter, score 2.8e-06 216591005966 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.3e-48 216591005967 PS00216 Sugar transport proteins signature 1. 216591005968 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591005969 hypothetical protein; Provisional; Region: PRK07236 216591005970 HMMPfam hit to PF01494, FAD binding domain, score 1.8e-05 216591005971 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 216591005972 active site 216591005973 Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021 216591005974 2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920 216591005975 acyl-activating enzyme (AAE) consensus motif; other site 216591005976 active site 216591005977 AMP binding site [chemical binding]; other site 216591005978 substrate binding site [chemical binding]; other site 216591005979 HMMPfam hit to PF00501, AMP-binding enzyme, score 4.2e-68 216591005980 PS00455 Putative AMP-binding domain signature. 216591005981 N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346 216591005982 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591005983 Zn binding site [ion binding]; other site 216591005984 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 5.2e-14 216591005985 PS00082 Extradiol ring-cleavage dioxygenases signature. 216591005986 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591005987 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591005988 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.6e-19 216591005989 Predicted helix-turn-helix motif with score 1917.000, SD 5.72 at aa 38-59, sequence TNINDIADAVGMTRTALYYYFP 216591005990 Transposase; Region: HTH_Tnp_1; pfam01527 216591005991 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591005992 HMMPfam hit to PF01527, Transposase, score 4.1e-08 216591005993 IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717 216591005994 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591005995 HMMPfam hit to PF05717, IS66 Orf2 like protein, score 5.2e-37 216591005996 Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007 216591005997 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591005998 putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005 216591005999 Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050 216591006000 IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817 216591006001 HMMPfam hit to PF03050, Transposase IS66 family, score 1.6e-73 216591006002 Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501 216591006003 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 216591006004 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 216591006005 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 216591006006 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 216591006007 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 1.2e-17 216591006008 Bacterial SH3 domain; Region: SH3_3; cl17532 216591006009 PS00018 EF-hand calcium-binding domain. 216591006010 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006011 1 probable transmembrane helix predicted for BCAL1167 by TMHMM2.0 at aa 4-21 216591006012 PAAR motif; Region: PAAR_motif; pfam05488 216591006013 HMMPfam hit to PF05488, PAAR motif, score 1.4e-06 216591006014 HMMPfam hit to PF05488, PAAR motif, score 0.00033 216591006015 CDS is interrupted by IS element insertion after codon 66. Similar to Pseudomonas syringae pv. tomato hypothetical protein UniProt:Q88BG3 (EMBL:AE016853) (147 aa) fasta scores: E()=7.9e-09, 36.129% id in 155 aa 216591006016 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591006017 Transposase; Region: HTH_Tnp_1; pfam01527 216591006018 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591006019 duplicated insertion sequence target 216591006020 Uncharacterized conserved protein [Function unknown]; Region: COG1479 216591006021 Protein of unknown function DUF262; Region: DUF262; pfam03235 216591006022 Protein of unknown function DUF262; Region: DUF262; pfam03235 216591006023 Protein of unknown function (DUF1524); Region: DUF1524; pfam07510 216591006024 HMMPfam hit to PF03235, Protein of unknown function DUF262, score 3.7e-15 216591006025 HMMPfam hit to PF07510, Protein of unknown function (DUF1524), score 2.2e-10 216591006026 Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007 216591006027 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591006028 putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005 216591006029 Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050 216591006030 IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817 216591006031 HMMPfam hit to PF03050, Transposase IS66 family, score 1.1e-99 216591006032 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591006033 IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717 216591006034 HMMPfam hit to PF05717, IS66 Orf2 like protein, score 3.2e-62 216591006035 Transposase; Region: HTH_Tnp_1; pfam01527 216591006036 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591006037 HMMPfam hit to PF01527, Transposase, score 1.2e-10 216591006038 Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566 216591006039 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591006040 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591006041 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.2e-17 216591006042 Predicted helix-turn-helix motif with score 1115.000, SD 2.98 at aa 105-126, sequence MRQSEAARRADLNAEVVSNEAR 216591006043 1 probable transmembrane helix predicted for BCAL1176 by TMHMM2.0 at aa 13-35 216591006044 Protein of unknown function (DUF1656); Region: DUF1656; pfam07869 216591006045 Fusaric acid resistance protein family; Region: FUSC; pfam04632 216591006046 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 216591006047 9 probable transmembrane helices predicted for BCAL1177 by TMHMM2.0 at aa 31-53, 78-100, 104-123, 130-147, 157-179, 396-418, 445-467, 474-493 and 525-547 216591006048 HMMPfam hit to PF04632, Fusaric acid resistance protein conserved re, score 7.3e-23 216591006049 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591006050 HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.7e-35 216591006051 HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.4e-22 216591006052 PS00036 bZIP transcription factors basic domain signature. 216591006053 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006054 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591006055 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591006056 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591006057 putative effector binding pocket; other site 216591006058 dimerization interface [polypeptide binding]; other site 216591006059 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-46 216591006060 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.2e-18 216591006061 PS00044 Bacterial regulatory proteins, lysR family signature. 216591006062 Predicted helix-turn-helix motif with score 1159.000, SD 3.13 at aa 22-43, sequence SSFIKAANLLNMSVGVASRHVA 216591006063 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591006064 transcriptional activator TtdR; Provisional; Region: PRK09801 216591006065 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591006066 putative effector binding pocket; other site 216591006067 dimerization interface [polypeptide binding]; other site 216591006068 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.4e-40 216591006069 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.8e-13 216591006070 Predicted helix-turn-helix motif with score 1010.000, SD 2.63 at aa 17-38, sequence GGISAGAFALHSSPPVVSRRLA 216591006071 Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929 216591006072 HMMPfam hit to PF02595, Glycerate kinase family, score 5.4e-60 216591006073 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591006074 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591006075 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591006076 PS00215 Mitochondrial energy transfer proteins signature. 216591006077 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.8e-15 216591006078 putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968 216591006079 Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100 216591006080 NAD(P) binding site [chemical binding]; other site 216591006081 catalytic residues [active] 216591006082 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 3.7e-133 216591006083 Probable gene remnant. Similar to C-terminus of Arthrobacter nicotinovorans putative sugar ABC transporter SWALL:Q8GAL0 (EMBL:AJ507836) (392 aa) fasta scores: E(): 3e-16, 43.2% id in 125 aa 216591006084 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006085 choline dehydrogenase; Validated; Region: PRK02106 216591006086 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 216591006087 HMMPfam hit to PF00732, GMC oxidoreductase, score 2.7e-51 216591006088 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006089 PS00623 GMC oxidoreductases signature 1. 216591006090 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 216591006091 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 216591006092 HMMPfam hit to PF05199, GMC oxidoreductase, score 4.3e-38 216591006093 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 216591006094 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 216591006095 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 5.7e-11 216591006096 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 0.2 216591006097 Protein of unknown function (DUF993); Region: DUF993; pfam06187 216591006098 HMMPfam hit to PF06187, Protein of unknown function (DUF993), score 7.4e-259 216591006099 Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082 216591006100 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 1.9e-26 216591006101 PS00215 Mitochondrial energy transfer proteins signature. 216591006102 Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139 216591006103 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006104 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 216591006105 10 probable transmembrane helices predicted for BCAL1191 by TMHMM2.0 at aa 45-67, 88-107, 147-169, 174-196, 206-228, 235-252, 257-276, 285-307, 322-344 and 357-376 216591006106 HMMPfam hit to PF01757, Acyltransferase family, score 1e-65 216591006107 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591006108 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591006109 non-specific DNA binding site [nucleotide binding]; other site 216591006110 salt bridge; other site 216591006111 sequence-specific DNA binding site [nucleotide binding]; other site 216591006112 HMMPfam hit to PF01381, Helix-turn-helix, score 2.4e-13 216591006113 Predicted helix-turn-helix motif with score 2054.000, SD 6.18 at aa 26-47, sequence LTQEKVAERLGIGLEAVSRMER 216591006114 1 probable transmembrane helix predicted for BCAL1194 by TMHMM2.0 at aa 18-40 216591006115 Methyltransferase domain; Region: Methyltransf_27; pfam13708 216591006116 3 probable transmembrane helices predicted for BCAL1196 by TMHMM2.0 at aa 5-27, 37-56 and 68-90 216591006117 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006118 YqaJ-like viral recombinase domain; Region: YqaJ; cl09232 216591006119 putative hydrolase; Provisional; Region: PRK11460 216591006120 phage/plasmid-like protein TIGR03299; Region: LGT_TIGR03299 216591006121 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006122 2 probable transmembrane helices predicted for BCAL1202 by TMHMM2.0 at aa 134-156 and 171-193 216591006123 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006124 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006125 DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462 216591006126 Part of AAA domain; Region: AAA_19; pfam13245 216591006127 Family description; Region: UvrD_C_2; pfam13538 216591006128 HMMPfam hit to PF00580, UvrD/REP helicase, score 3e-08 216591006129 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006130 oxidoreductase; Provisional; Region: PRK06128 216591006131 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591006132 NAD(P) binding site [chemical binding]; other site 216591006133 active site 216591006134 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.9e-26 216591006135 PS00061 Short-chain dehydrogenases/reductases family signature. 216591006136 NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604 216591006137 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 216591006138 NAD(P) binding site [chemical binding]; other site 216591006139 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.5e-25 216591006140 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 1.6e-15 216591006141 DoxX; Region: DoxX; pfam07681 216591006142 4 probable transmembrane helices predicted for BCAL1208 by TMHMM2.0 at aa 19-41, 56-78, 85-104 and 114-136 216591006143 HMMPfam hit to PF07681, DoxX, score 8e-30 216591006144 PS00962 Ribosomal protein S2 signature 1. 216591006145 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 216591006146 Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933 216591006147 FMN binding site [chemical binding]; other site 216591006148 active site 216591006149 substrate binding site [chemical binding]; other site 216591006150 catalytic residue [active] 216591006151 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 8.6e-85 216591006152 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591006153 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591006154 LysR substrate binding domain; Region: LysR_substrate; pfam03466 216591006155 dimerization interface [polypeptide binding]; other site 216591006156 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.9e-22 216591006157 Predicted helix-turn-helix motif with score 997.000, SD 2.58 at aa 20-41, sequence GSFSGAARRLERAQSVVSYAIA 216591006158 PS00044 Bacterial regulatory proteins, lysR family signature. 216591006159 HMMPfam hit to PF03466, LysR substrate binding domain, score 7e-24 216591006160 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853 216591006161 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal; Region: OxoDH_E1alpha_N; pfam12573 216591006162 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071 216591006163 Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000 216591006164 tetramer interface [polypeptide binding]; other site 216591006165 TPP-binding site [chemical binding]; other site 216591006166 heterodimer interface [polypeptide binding]; other site 216591006167 phosphorylation loop region [posttranslational modification] 216591006168 HMMPfam hit to PF00676, Dehydrogenase E1 component, score 5.6e-135 216591006169 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022 216591006170 Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036 216591006171 alpha subunit interface [polypeptide binding]; other site 216591006172 TPP binding site [chemical binding]; other site 216591006173 heterodimer interface [polypeptide binding]; other site 216591006174 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 216591006175 HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 3.6e-76 216591006176 HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 2.7e-56 216591006177 branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856 216591006178 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 216591006179 E3 interaction surface; other site 216591006180 lipoyl attachment site [posttranslational modification]; other site 216591006181 e3 binding domain; Region: E3_binding; pfam02817 216591006182 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 216591006183 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 1.2e-21 216591006184 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 216591006185 HMMPfam hit to PF02817, e3 binding domain, score 5.2e-12 216591006186 HMMPfam hit to PF00198, 2-oxoacid dehydrogenases acyltransferas, score 8.3e-113 216591006187 dihydrolipoamide dehydrogenase; Validated; Region: PRK05976 216591006188 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591006189 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591006190 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 216591006191 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 1.5e-52 216591006192 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 216591006193 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006194 PS00435 Peroxidases proximal heme-ligand signature. 216591006195 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 1.1e-29 216591006196 HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 2.1e-41 216591006197 CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250 216591006198 NADH(P)-binding; Region: NAD_binding_10; pfam13460 216591006199 NAD binding site [chemical binding]; other site 216591006200 active site 216591006201 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591006202 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591006203 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591006204 dimerization interface [polypeptide binding]; other site 216591006205 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.4e-20 216591006206 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 9.8e-17 216591006207 Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592 216591006208 agmatinase; Region: agmatinase; TIGR01230 216591006209 oligomer interface [polypeptide binding]; other site 216591006210 putative active site [active] 216591006211 Mn binding site [ion binding]; other site 216591006212 HMMPfam hit to PF00491, Arginase family, score 5.4e-69 216591006213 PS00147 Arginase family signature 1. 216591006214 PS00148 Arginase family signature 2. 216591006215 PS01053 Arginase family signature 3. 216591006216 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 216591006217 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591006218 Coenzyme A binding pocket [chemical binding]; other site 216591006219 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 7.6e-10 216591006220 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006221 Purine-cytosine permease and related proteins [Nucleotide transport and metabolism]; Region: CodB; COG1457 216591006222 Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133 216591006223 Na binding site [ion binding]; other site 216591006224 HMMPfam hit to PF02133, Permease for cytosine/purines, uracil,, score 4.7e-41 216591006225 13 probable transmembrane helices predicted for BCAL1220 by TMHMM2.0 at aa 34-56, 61-83, 98-120, 141-158, 163-185, 198-217, 237-259, 272-294, 299-318, 330-352, 357-379, 400-422 and 437-454 216591006226 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591006227 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591006228 trimer interface [polypeptide binding]; other site 216591006229 eyelet of channel; other site 216591006230 HMMPfam hit to PF00267, Gram-negative porin, score 5e-06 216591006231 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591006232 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591006233 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591006234 dimerization interface [polypeptide binding]; other site 216591006235 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.5e-28 216591006236 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.1e-22 216591006237 PS00044 Bacterial regulatory proteins, lysR family signature. 216591006238 Predicted helix-turn-helix motif with score 1693.000, SD 4.95 at aa 28-49, sequence RSVSRAAARLHVTQPAVSQALR 216591006239 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591006240 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591006241 putative substrate translocation pore; other site 216591006242 HMMPfam hit to PF00083, Sugar (and other) transporter, score 7.5e-07 216591006243 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.6e-25 216591006244 12 probable transmembrane helices predicted for BCAL1223 by TMHMM2.0 at aa 19-41, 56-78, 87-109, 119-141, 153-175, 190-209, 238-260, 275-297, 304-323, 333-355, 368-390 and 395-417 216591006245 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 216591006246 allantoate amidohydrolase; Reviewed; Region: PRK12893 216591006247 M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884 216591006248 active site 216591006249 metal binding site [ion binding]; metal-binding site 216591006250 dimer interface [polypeptide binding]; other site 216591006251 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 1.4e-41 216591006252 Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123 216591006253 Histone deacetylase class IIa; Region: HDAC_classII_APAH; cd10001 216591006254 active site 216591006255 Zn binding site [ion binding]; other site 216591006256 HMMPfam hit to PF00850, Histone deacetylase domain, score 1.9e-58 216591006257 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591006258 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591006259 putative substrate translocation pore; other site 216591006260 12 probable transmembrane helices predicted for BCAL1226 by TMHMM2.0 at aa 13-35, 55-77, 84-103, 113-135, 142-164, 174-193, 214-236, 246-268, 281-300, 304-323, 336-358 and 363-385 216591006261 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.2e-41 216591006262 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591006263 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591006264 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 216591006265 dimerization interface [polypeptide binding]; other site 216591006266 substrate binding pocket [chemical binding]; other site 216591006267 HMMPfam hit to PF03466, LysR substrate binding domain, score 4e-32 216591006268 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006269 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1e-19 216591006270 PS00044 Bacterial regulatory proteins, lysR family signature. 216591006271 Predicted helix-turn-helix motif with score 1099.000, SD 2.93 at aa 19-40, sequence GSVMAGARAAGIVQPALSRQIR 216591006272 Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291 216591006273 Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342 216591006274 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591006275 catalytic residue [active] 216591006276 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 6.8e-50 216591006277 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006278 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 216591006279 Uncharacterized protein conserved in bacteria (DUF2242); Region: DUF2242; pfam10001 216591006280 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006281 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591006282 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591006283 dimerization interface [polypeptide binding]; other site 216591006284 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.1e-09 216591006285 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.5e-09 216591006286 PS00044 Bacterial regulatory proteins, lysR family signature. 216591006287 Predicted helix-turn-helix motif with score 1165.000, SD 3.15 at aa 4-25, sequence GGFARAAARLDMAVQTISAQVR 216591006288 Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861 216591006289 7 probable transmembrane helices predicted for BCAL1231 by TMHMM2.0 at aa 13-35, 54-76, 86-103, 123-145, 160-182, 189-208 and 218-237 216591006290 HMMPfam hit to PF03741, Integral membrane protein TerC family, score 1.9e-36 216591006291 PS00030 Eukaryotic putative RNA-binding region RNP-1 signature. 216591006292 Transcription factor zinc-finger; Region: zf-TFIIB; cl01565 216591006293 Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071 216591006294 Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464 216591006295 putative dimer interface [polypeptide binding]; other site 216591006296 HMMPfam hit to PF00011, Hsp20/alpha crystallin family, score 7.3e-18 216591006297 Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071 216591006298 Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464 216591006299 putative dimer interface [polypeptide binding]; other site 216591006300 HMMPfam hit to PF00011, Hsp20/alpha crystallin family, score 2.3e-15 216591006301 3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK07066 216591006302 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 216591006303 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 216591006304 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD binding, score 1.5e-65 216591006305 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 9.1e-07 216591006306 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591006307 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591006308 LysR substrate binding domain; Region: LysR_substrate; pfam03466 216591006309 dimerization interface [polypeptide binding]; other site 216591006310 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.2e-28 216591006311 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.5e-21 216591006312 PS00044 Bacterial regulatory proteins, lysR family signature. 216591006313 Predicted helix-turn-helix motif with score 2224.000, SD 6.76 at aa 19-40, sequence GSFTAASERVNLSQSTVSQHIR 216591006314 Malonate transporter MadL subunit; Region: MadL; cl04273 216591006315 HMMPfam hit to PF03817, Malonate transporter MadL subunit, score 3e-71 216591006316 4 probable transmembrane helices predicted for BCAL1238 by TMHMM2.0 at aa 7-29, 33-50, 63-80 and 90-112 216591006317 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006318 Malonate/sodium symporter MadM subunit; Region: MadM; cl04274 216591006319 HMMPfam hit to PF03818, Malonate/sodium symporter MadM subunit, score 6.3e-29 216591006320 8 probable transmembrane helices predicted for BCAL1239 by TMHMM2.0 at aa 5-27, 34-56, 71-93, 106-128, 132-154, 161-183, 193-215 and 222-244 216591006321 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006322 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006323 malonate decarboxylase, alpha subunit; Region: mdcA; TIGR01110 216591006324 Coenzyme A transferase; Region: CoA_trans; cl17247 216591006325 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006326 malonate decarboxylase subunit delta; Provisional; Region: PRK02103 216591006327 HMMPfam hit to PF06857, Malonate decarboxylase delta subunit (MdcD), score 9.6e-52 216591006328 malonate decarboxylase subunit beta; Reviewed; Region: PRK07189 216591006329 HMMPfam hit to PF01039, Carboxyl transferase domain, score 0.0035 216591006330 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006331 malonate decarboxylase, gamma subunit; Region: malonate_gamma; TIGR03134 216591006332 HMMPfam hit to PF06833, Malonate decarboxylase gamma subunit (MdcE), score 7.6e-85 216591006333 phosphoribosyl-dephospho-CoA transferase; Provisional; Region: PRK02098 216591006334 Phosphoribosyl-dephospho-CoA transferase MdcG; Region: MdcG; pfam10620 216591006335 triphosphoribosyl-dephospho-CoA synthase MdcB; Region: malonate_mdcB; TIGR03132 216591006336 HMMPfam hit to PF01874, ATP:dephospho-CoA triphosphoribosyl transfer, score 3.6e-56 216591006337 malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128 216591006338 malonate decarboxylase, epsilon subunit; Region: malonate_mdcH; TIGR03131 216591006339 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 216591006340 putative active site [active] 216591006341 catalytic site [active] 216591006342 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 216591006343 active site 216591006344 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 9.7e-07 216591006345 Poly-beta-hydroxyalkanoate depolymerase [Lipid metabolism]; Region: DepA; COG4553 216591006346 PHB de-polymerase C-terminus; Region: PHB_depo_C; pfam06850 216591006347 HMMPfam hit to PF06850, PHB de-polymerase C-terminus, score 8.1e-39 216591006348 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006349 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591006350 Glutathione S-transferase, N-terminal domain; Region: GST_N_3; pfam13417 216591006351 C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776 216591006352 N-terminal domain interface [polypeptide binding]; other site 216591006353 dimer interface [polypeptide binding]; other site 216591006354 substrate binding pocket (H-site) [chemical binding]; other site 216591006355 phage conserved hypothetical protein BR0599; Region: phg_TIGR02218 216591006356 proline/glycine betaine transporter; Provisional; Region: PRK10642 216591006357 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591006358 putative substrate translocation pore; other site 216591006359 HMMPfam hit to PF00083, Sugar (and other) transporter, score 2e-43 216591006360 12 probable transmembrane helices predicted for BCAL1252 by TMHMM2.0 at aa 41-63, 78-100, 113-135, 145-167, 180-202, 212-234, 271-293, 308-330, 337-359, 369-391, 400-422 and 432-451 216591006361 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.3e-33 216591006362 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006363 PS00216 Sugar transport proteins signature 1. 216591006364 PS00217 Sugar transport proteins signature 2. 216591006365 hypothetical protein; Provisional; Region: PRK02237 216591006366 HMMPfam hit to PF02694, Uncharacterised BCR, YnfA/UPF0060 family, score 4.1e-43 216591006367 4 probable transmembrane helices predicted for BCAL1253 by TMHMM2.0 at aa 50-72, 77-99, 106-123 and 127-149 216591006368 DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406 216591006369 DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131 216591006370 active site 216591006371 catalytic site [active] 216591006372 substrate binding site [chemical binding]; other site 216591006373 HMMPfam hit to PF00929, Exonuclease, score 3.6e-38 216591006374 RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278 216591006375 RNA/DNA hybrid binding site [nucleotide binding]; other site 216591006376 active site 216591006377 HMMPfam hit to PF00075, RNase H, score 5e-58 216591006378 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591006379 HMMPfam hit to PF08241, Methyltransferase domain, score 5.2e-07 216591006380 Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446 216591006381 membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783 216591006382 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591006383 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591006384 catalytic residue [active] 216591006385 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107 216591006386 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 216591006387 HMMPfam hit to PF06474, MLTD_N, score 3.6e-17 216591006388 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006389 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 4.7e-27 216591006390 PS00922 Prokaryotic transglycosylases signature. 216591006391 HMMPfam hit to PF01476, LysM domain, score 0.00074 216591006392 HMMPfam hit to PF01476, LysM domain, score 5.4e-06 216591006393 Predicted helix-turn-helix motif with score 1282.000, SD 3.55 at aa 417-438, sequence QSMAALAGRYGVSVGQLKAWNR 216591006394 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591006395 D-galactonate transporter; Region: 2A0114; TIGR00893 216591006396 putative substrate translocation pore; other site 216591006397 11 probable transmembrane helices predicted for BCAL1259 by TMHMM2.0 at aa 28-50, 57-79, 94-116, 123-145, 155-177, 182-201, 267-289, 296-318, 328-350, 362-384 and 394-416 216591006398 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.8e-31 216591006399 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006400 carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564 216591006401 Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097 216591006402 Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744 216591006403 catalytic site [active] 216591006404 subunit interface [polypeptide binding]; other site 216591006405 HMMPfam hit to PF00988, Carbamoyl-phosphate synthase small ch, score 1e-87 216591006406 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 9.8e-70 216591006407 PS00442 Glutamine amidotransferases class-I active site. 216591006408 leucine export protein LeuE; Provisional; Region: PRK10958 216591006409 6 probable transmembrane helices predicted for BCAL1261 by TMHMM2.0 at aa 13-35, 48-70, 74-96, 126-148, 159-181 and 194-216 216591006410 HMMPfam hit to PF01810, LysE type translocator, score 1.6e-55 216591006411 carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294 216591006412 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 216591006413 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 216591006414 Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787 216591006415 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 216591006416 ATP-grasp domain; Region: ATP-grasp_4; cl17255 216591006417 Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424 216591006418 IMP binding site; other site 216591006419 dimer interface [polypeptide binding]; other site 216591006420 interdomain contacts; other site 216591006421 partial ornithine binding site; other site 216591006422 HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 1.1e-59 216591006423 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006424 HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 1.8e-129 216591006425 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 216591006426 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 216591006427 HMMPfam hit to PF02787, Carbamoyl-phosphate synthetase large c, score 3.2e-60 216591006428 HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 2.7e-25 216591006429 HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 1.3e-19 216591006430 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 216591006431 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 216591006432 HMMPfam hit to PF02142, MGS-like domain, score 6.6e-33 216591006433 transcription elongation factor GreA; Reviewed; Region: greA; PRK00226 216591006434 Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449 216591006435 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 216591006436 HMMPfam hit to PF03449, Prokaryotic transcription elongation fact, score 2.9e-39 216591006437 PS00829 Prokaryotic transcription elongation factors signature 1. 216591006438 HMMPfam hit to PF01272, Prokaryotic transcription elongation fact, score 3.8e-33 216591006439 PS00830 Prokaryotic transcription elongation factors signature 2. 216591006440 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006441 Domain of unknown function (DUF4149); Region: DUF4149; pfam13664 216591006442 4 probable transmembrane helices predicted for BCAL1264 by TMHMM2.0 at aa 5-27, 42-64, 77-99 and 123-145 216591006443 Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly; Region: CRS1_YhbY; smart01103 216591006444 HMMPfam hit to PF01985, CRS1 / YhbY domain, score 8.5e-32 216591006445 23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293 216591006446 FtsJ-like methyltransferase; Region: FtsJ; cl17430 216591006447 HMMPfam hit to PF01728, FtsJ-like methyltransferase, score 2.8e-60 216591006448 ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465 216591006449 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591006450 Walker A motif; other site 216591006451 ATP binding site [chemical binding]; other site 216591006452 Walker B motif; other site 216591006453 arginine finger; other site 216591006454 Peptidase family M41; Region: Peptidase_M41; pfam01434 216591006455 2 probable transmembrane helices predicted for BCAL1267 by TMHMM2.0 at aa 5-23 and 100-122 216591006456 HMMPfam hit to PF06480, FtsH Extracellular, score 2.1e-36 216591006457 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006458 HMMPfam hit to PF00004, ATPase family associated with various c, score 1.9e-99 216591006459 HMMPfam hit to PF07728, ATPase family associated with various c, score 0.00068 216591006460 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006461 PS00674 AAA-protein family signature. 216591006462 HMMPfam hit to PF01434, Peptidase family M41, score 1.5e-104 216591006463 DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739 216591006464 dihydropteroate synthase; Region: DHPS; TIGR01496 216591006465 substrate binding pocket [chemical binding]; other site 216591006466 dimer interface [polypeptide binding]; other site 216591006467 inhibitor binding site; inhibition site 216591006468 PS00792 Dihydropteroate synthase signature 1. 216591006469 HMMPfam hit to PF00809, Pterin binding enzyme, score 3.3e-84 216591006470 PS00793 Dihydropteroate synthase signature 2. 216591006471 phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887 216591006472 GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802 216591006473 active site 216591006474 substrate binding site [chemical binding]; other site 216591006475 metal binding site [ion binding]; metal-binding site 216591006476 HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 8.1e-57 216591006477 PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 216591006478 HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 3.5e-36 216591006479 HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 4.2e-20 216591006480 HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-, score 2e-09 216591006481 PBP superfamily domain; Region: PBP_like_2; cl17296 216591006482 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 4.6e-24 216591006483 1 probable transmembrane helix predicted for BCAL1270 by TMHMM2.0 at aa 7-29 216591006484 phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275 216591006485 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591006486 dimer interface [polypeptide binding]; other site 216591006487 conserved gate region; other site 216591006488 putative PBP binding loops; other site 216591006489 ABC-ATPase subunit interface; other site 216591006490 6 probable transmembrane helices predicted for BCAL1271 by TMHMM2.0 at aa 31-53, 87-109, 121-143, 175-197, 236-258 and 299-321 216591006491 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2e-14 216591006492 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591006493 phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268 216591006494 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591006495 dimer interface [polypeptide binding]; other site 216591006496 conserved gate region; other site 216591006497 putative PBP binding loops; other site 216591006498 ABC-ATPase subunit interface; other site 216591006499 6 probable transmembrane helices predicted for BCAL1272 by TMHMM2.0 at aa 21-43, 74-96, 117-136, 141-159, 191-213 and 254-276 216591006500 PS00962 Ribosomal protein S2 signature 1. 216591006501 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 7.8e-29 216591006502 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591006503 phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744 216591006504 ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260 216591006505 Walker A/P-loop; other site 216591006506 ATP binding site [chemical binding]; other site 216591006507 Q-loop/lid; other site 216591006508 ABC transporter signature motif; other site 216591006509 Walker B; other site 216591006510 D-loop; other site 216591006511 H-loop/switch region; other site 216591006512 HMMPfam hit to PF00005, ABC transporter, score 5.4e-67 216591006513 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006514 PS00211 ABC transporters family signature. 216591006515 transcriptional regulator PhoU; Provisional; Region: PRK11115 216591006516 PhoU domain; Region: PhoU; pfam01895 216591006517 PhoU domain; Region: PhoU; pfam01895 216591006518 HMMPfam hit to PF01895, PhoU family, score 3.9e-26 216591006519 HMMPfam hit to PF01895, PhoU family, score 1.2e-23 216591006520 phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154 216591006521 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591006522 active site 216591006523 phosphorylation site [posttranslational modification] 216591006524 intermolecular recognition site; other site 216591006525 dimerization interface [polypeptide binding]; other site 216591006526 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591006527 DNA binding site [nucleotide binding] 216591006528 HMMPfam hit to PF00072, Response regulator receiver domain, score 5.9e-31 216591006529 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 3.5e-23 216591006530 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 216591006531 PAS domain; Region: PAS; smart00091 216591006532 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591006533 dimer interface [polypeptide binding]; other site 216591006534 phosphorylation site [posttranslational modification] 216591006535 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591006536 ATP binding site [chemical binding]; other site 216591006537 Mg2+ binding site [ion binding]; other site 216591006538 G-X-G motif; other site 216591006539 1 probable transmembrane helix predicted for BCAL1276 by TMHMM2.0 at aa 13-35 216591006540 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.8e-25 216591006541 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5.6e-41 216591006542 polyphosphate kinase; Provisional; Region: PRK05443 216591006543 Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089 216591006544 Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503 216591006545 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 216591006546 putative active site [active] 216591006547 catalytic site [active] 216591006548 Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168 216591006549 putative domain interface [polypeptide binding]; other site 216591006550 putative active site [active] 216591006551 catalytic site [active] 216591006552 HMMPfam hit to PF02503, Polyphosphate kinase, score 0 216591006553 Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248 216591006554 Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541 216591006555 HMMPfam hit to PF02541, Ppx/GppA phosphatase family, score 1.6e-70 216591006556 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 216591006557 catalytic core [active] 216591006558 HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 3.8e-14 216591006559 Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; cl17496 216591006560 PS00228 Tubulin-beta mRNA autoregulation signal. 216591006561 1 probable transmembrane helix predicted for BCAL1282 by TMHMM2.0 at aa 6-25 216591006562 DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136 216591006563 DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367 216591006564 12 probable transmembrane helices predicted for BCAL1285 by TMHMM2.0 at aa 21-40, 55-77, 98-120, 147-164, 171-193, 198-220, 252-269, 284-306, 327-349, 364-386, 393-415 and 420-442 216591006565 HMMPfam hit to PF01554, MatE, score 2.5e-27 216591006566 Protein of unknown function (DUF2288); Region: DUF2288; pfam10052 216591006567 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365 216591006568 Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS); Region: MACS_like_3; cd05971 216591006569 active site 216591006570 acyl-activating enzyme (AAE) consensus motif; other site 216591006571 putative CoA binding site [chemical binding]; other site 216591006572 AMP binding site [chemical binding]; other site 216591006573 HMMPfam hit to PF00501, AMP-binding enzyme, score 4e-106 216591006574 PS00455 Putative AMP-binding domain signature. 216591006575 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 216591006576 FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388 216591006577 Peptidase family M23; Region: Peptidase_M23; pfam01551 216591006578 HMMPfam hit to PF01551, Peptidase family M23, score 5e-47 216591006579 HMMPfam hit to PF01476, LysM domain, score 4.5e-16 216591006580 1 probable transmembrane helix predicted for BCAL1288 by TMHMM2.0 at aa 9-31 216591006581 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006582 aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648 216591006583 active site 216591006584 catalytic residues [active] 216591006585 HMMPfam hit to PF01263, Aldose 1-epimerase, score 4.1e-10 216591006586 undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK12554 216591006587 HMMPfam hit to PF02673, Bacitracin resistance protein BacA, score 3.4e-63 216591006588 7 probable transmembrane helices predicted for BCAL1290 by TMHMM2.0 at aa 7-29, 44-66, 87-108, 118-135, 156-178, 220-242 and 249-271 216591006589 BcenGI6 216591006590 Protein of unknown function (DUF3592); Region: DUF3592; pfam12158 216591006591 2 probable transmembrane helices predicted for BCAL1291 by TMHMM2.0 at aa 5-22 and 96-118 216591006592 2 probable transmembrane helices predicted for BCAL1292 by TMHMM2.0 at aa 135-157 and 167-189 216591006593 Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3519 216591006594 Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947 216591006595 HMMPfam hit to PF05947, Bacterial protein of unknown function (DUF87, score 2.2e-127 216591006596 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 216591006597 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 216591006598 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 216591006599 Gp5 C-terminal repeat (3 copies); Region: Gp5_C; pfam06715 216591006600 Gp5 C-terminal repeat (3 copies); Region: Gp5_C; pfam06715 216591006601 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 2.4e-53 216591006602 HMMPfam hit to PF06715, Gp5 C-terminal repeat (3 copies), score 0.00012 216591006603 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006604 Uncharacterized protein conserved in bacteria (DUF2169); Region: DUF2169; pfam09937 216591006605 Domain of unknown function (DUF4150); Region: DUF4150; pfam13665 216591006606 PS00120 Lipases, serine active site. 216591006607 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591006608 Ankyrin repeats (3 copies); Region: Ank_2; pfam12796 216591006609 ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204 216591006610 Ankyrin repeats (3 copies); Region: Ank_2; pfam12796 216591006611 HMMPfam hit to PF00023, Ankyrin repeat, score 0.48 216591006612 HMMPfam hit to PF00023, Ankyrin repeat, score 0.028 216591006613 HMMPfam hit to PF00023, Ankyrin repeat, score 0.02 216591006614 HNH/ENDO VII superfamily nuclease with conserved GHE residues; Region: GH-E; pfam14410 216591006615 PS00213 Lipocalin signature. 216591006616 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591006617 binding surface 216591006618 TPR motif; other site 216591006619 3 probable transmembrane helices predicted for BCAL1301 by TMHMM2.0 at aa 13-35, 135-157 and 177-199 216591006620 CDS is interrupted by an IS element insertion after codon 125. Similar to Xanthomonas campestris pv. campestris hypothetical protein xcc1451. UniProt:Q8PAM9 (EMBL:AE012245) (238 aa) fasta scores: E()=2.9e-23, 38.559% id in 236 aa 216591006621 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591006622 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591006623 transposase/IS protein; Provisional; Region: PRK09183 216591006624 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591006625 Walker A motif; other site 216591006626 ATP binding site [chemical binding]; other site 216591006627 Walker B motif; other site 216591006628 HMMPfam hit to PF01695, IstB-like ATP binding protein, score 9.6e-88 216591006629 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006630 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584 216591006631 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 216591006632 DNA-binding interface [nucleotide binding]; DNA binding site 216591006633 Integrase core domain; Region: rve; pfam00665 216591006634 HMMPfam hit to PF00665, Integrase core domain, score 2.7e-25 216591006635 HMMPfam hit to PF02796, Helix-turn-helix domain of resolvase, score 0.0028 216591006636 Predicted helix-turn-helix motif with score 2020.000, SD 6.07 at aa 18-39, sequence VSEREIARRLGISRNTVARYLS 216591006637 CDS is interupted by at least two IS element insertion events after codons 492 and 696. Similar to Psychrobacter cryohalolentis (strain K5) SNF2-related protein UniProt:Q1QC66 (EMBL:CP000323) (1075 aa) fasta scores: E()=2e-102, 39.794% id in 1068 aa 216591006638 HMMPfam hit to PF00665, Integrase core domain, score 9.5e-40 216591006639 HMMPfam hit to PF01527, Transposase, score 3.6e-22 216591006640 Predicted helix-turn-helix motif with score 1325.000, SD 3.70 at aa 18-39, sequence TPVAEVCRKMGISDATFYNWRT 216591006641 HMMPfam hit to PF00176, SNF2 family N-terminal domain, score 3.7e-60 216591006642 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591006643 Transposase; Region: HTH_Tnp_1; pfam01527 216591006644 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591006645 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 7.9e-10 216591006646 Nuclease-related domain; Region: NERD; pfam08378 216591006647 Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515 216591006648 Protein Kinases, catalytic domain; Region: PKc_like; cl09925 216591006649 activation loop (A-loop); other site 216591006650 Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515 216591006651 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120 216591006652 active site 216591006653 substrate binding site [chemical binding]; other site 216591006654 ATP binding site [chemical binding]; other site 216591006655 AAA domain; Region: AAA_11; pfam13086 216591006656 Part of AAA domain; Region: AAA_19; pfam13245 216591006657 Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112 216591006658 AAA domain; Region: AAA_12; pfam13087 216591006659 HMMPfam hit to PF08378, Nuclease-related domain, score 1.7e-07 216591006660 PS00108 Serine/Threonine protein kinases active-site signature. 216591006661 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006662 Domain of unknown function (DUF4102); Region: DUF4102; pfam13356 216591006663 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 216591006664 active site 216591006665 DNA binding site [nucleotide binding] 216591006666 Int/Topo IB signature motif; other site 216591006667 HMMPfam hit to PF00589, Phage integrase family, score 1.6e-06 216591006668 Nitrate and nitrite sensing; Region: NIT; pfam08376 216591006669 ANTAR domain; Region: ANTAR; pfam03861 216591006670 HMMPfam hit to PF08376, Nitrate and nitrite sensing, score 3.7e-51 216591006671 HMMPfam hit to PF03861, ANTAR domain, score 6.9e-14 216591006672 Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226 216591006673 HMMPfam hit to PF01226, Formate/nitrite transporter, score 7.1e-22 216591006674 6 probable transmembrane helices predicted for BCAL1319 by TMHMM2.0 at aa 29-51, 66-88, 109-131, 182-204, 211-230 and 240-257 216591006675 Hemerythrin-like domain; Region: Hr-like; cd12108 216591006676 Fe binding site [ion binding]; other site 216591006677 HMMPfam hit to PF01814, Hemerythrin HHE cation binding domain, score 0.0038 216591006678 HMMPfam hit to PF01814, Hemerythrin HHE cation binding domain, score 0.033 216591006679 glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331 216591006680 Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans). The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714 216591006681 glutaminase active site [active] 216591006682 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 216591006683 dimer interface [polypeptide binding]; other site 216591006684 active site 216591006685 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 216591006686 dimer interface [polypeptide binding]; other site 216591006687 active site 216591006688 HMMPfam hit to PF01380, SIS domain, score 2.3e-22 216591006689 HMMPfam hit to PF01380, SIS domain, score 2.4e-29 216591006690 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 4.6e-37 216591006691 Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; Region: CE4_u2; cd10926 216591006692 putative active site [active] 216591006693 1 probable transmembrane helix predicted for BCAL1323 by TMHMM2.0 at aa 13-35 216591006694 6 probable transmembrane helices predicted for BCAL1324 by TMHMM2.0 at aa 24-46, 89-111, 118-140, 155-177, 189-211 and 216-238 216591006695 Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519 216591006696 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006697 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591006698 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006699 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 216591006700 CESA_like is the cellulose synthase superfamily; Region: CESA_like; cd06423 216591006701 DXD motif; other site 216591006702 4 probable transmembrane helices predicted for BCAL1327 by TMHMM2.0 at aa 41-63, 344-366, 381-403 and 416-438 216591006703 HMMPfam hit to PF00535, Glycosyl transferase family, score 4.1e-26 216591006704 UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381 216591006705 Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786 216591006706 active site 216591006707 homodimer interface [polypeptide binding]; other site 216591006708 HMMPfam hit to PF02350, UDP-N-acetylglucosamine 2-epimerase, score 9.4e-164 216591006709 Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR5; cd08271 216591006710 NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604 216591006711 putative NAD(P) binding site [chemical binding]; other site 216591006712 substrate binding site [chemical binding]; other site 216591006713 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 1.5e-09 216591006714 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 9.1e-05 216591006715 4-hydroxybenzoyl-CoA reductase, gamma subunit; Region: 4hydroxCoAred; TIGR03193 216591006716 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591006717 catalytic loop [active] 216591006718 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cl00159 216591006719 iron binding site [ion binding]; other site 216591006720 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 216591006721 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 1.3e-10 216591006722 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591006723 HMMPfam hit to PF01799, [2Fe-2S] binding domain, score 1.8e-34 216591006724 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591006725 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 216591006726 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 216591006727 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591006728 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591006729 HMMPfam hit to PF02738, Aldehyde oxidase and xanthine dehydroge, score 9.3e-10 216591006730 Predicted helix-turn-helix motif with score 1142.000, SD 3.08 at aa 395-416, sequence TTRDELAKALGLPAERVTVNVT 216591006731 aldolase II superfamily protein; Provisional; Region: PRK07044 216591006732 intersubunit interface [polypeptide binding]; other site 216591006733 active site 216591006734 Zn2+ binding site [ion binding]; other site 216591006735 HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 2.6e-68 216591006736 Acyl-CoA dehydrogenase N terminal; Region: AcylCoA_DH_N; pfam12418 216591006737 acyl-CoA dehydrogenase; Provisional; Region: PTZ00456 216591006738 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591006739 active site 216591006740 Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806 216591006741 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 2.6e-14 216591006742 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 5.4e-27 216591006743 PS00073 Acyl-CoA dehydrogenases signature 2. 216591006744 PS00216 Sugar transport proteins signature 1. 216591006745 NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604 216591006746 Quinone oxidoreductase (QOR); Region: QOR1; cd08241 216591006747 NAD(P) binding site [chemical binding]; other site 216591006748 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 2.6e-22 216591006749 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.3e-41 216591006750 Predicted transcriptional regulators [Transcription]; Region: COG1695 216591006751 Transcriptional regulator PadR-like family; Region: PadR; cl17335 216591006752 Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400 216591006753 HMMPfam hit to PF03551, Transcriptional regulator PadR-like family, score 3.4e-07 216591006754 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 216591006755 2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930 216591006756 active site 216591006757 FMN binding site [chemical binding]; other site 216591006758 2,4-decadienoyl-CoA binding site; other site 216591006759 catalytic residue [active] 216591006760 4Fe-4S cluster binding site [ion binding]; other site 216591006761 Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446 216591006762 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591006763 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 9.8e-110 216591006764 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoredu, score 8.8e-05 216591006765 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoredu, score 0.0011 216591006766 SnoaL-like domain; Region: SnoaL_2; pfam12680 216591006767 Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267 216591006768 Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886 216591006769 3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183 216591006770 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591006771 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591006772 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591006773 HMMPfam hit to PF01494, FAD binding domain, score 1.9e-51 216591006774 Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454 216591006775 Maleylacetate reductase is involved in many aromatic compounds degradation pathways of aerobic microbes; Region: MAR; cd08177 216591006776 active site 216591006777 dimer interface [polypeptide binding]; other site 216591006778 metal binding site [ion binding]; metal-binding site 216591006779 HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 1.3e-15 216591006780 Stress responsive A/B Barrel Domain; Region: Dabb; smart00886 216591006781 HMMPfam hit to PF07876, Stress responsive A/B Barrel Domain, score 6.8e-19 216591006782 Hydroxyquinol 1,2-dioxygenase (1,2-HQD) catalyzes the ring cleavage of hydroxyquinol (1,2,4-trihydroxybenzene), a intermediate in the degradation of a large variety of aromatic compounds including some polychloro- and nitroaromatic pollutants, to form...; Region: 1,2-HQD; cd03461 216591006783 chlorocatechol 1,2-dioxygenase; Region: chlorocat_1_2; TIGR02465 216591006784 dimer interface [polypeptide binding]; other site 216591006785 active site 216591006786 HMMPfam hit to PF00775, Dioxygenase, score 1.5e-83 216591006787 PS00083 Intradiol ring-cleavage dioxygenases signature. 216591006788 HMMPfam hit to PF04444, Catechol dioxygenase N terminus, score 5.7e-30 216591006789 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006790 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591006791 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591006792 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591006793 putative effector binding pocket; other site 216591006794 dimerization interface [polypeptide binding]; other site 216591006795 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.2e-19 216591006796 Predicted helix-turn-helix motif with score 1740.000, SD 5.11 at aa 17-38, sequence GSLSKAAERLGMSSAAASRCLN 216591006797 PS00044 Bacterial regulatory proteins, lysR family signature. 216591006798 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.4e-52 216591006799 Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768 216591006800 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 216591006801 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591006802 N-terminal plug; other site 216591006803 ligand-binding site [chemical binding]; other site 216591006804 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.7e-24 216591006805 HMMPfam hit to PF00593, TonB dependent receptor, score 3.7e-19 216591006806 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 216591006807 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 216591006808 Walker A/P-loop; other site 216591006809 ATP binding site [chemical binding]; other site 216591006810 Q-loop/lid; other site 216591006811 ABC transporter signature motif; other site 216591006812 Walker B; other site 216591006813 D-loop; other site 216591006814 H-loop/switch region; other site 216591006815 HMMPfam hit to PF00005, ABC transporter, score 1.2e-52 216591006816 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006817 PS00211 ABC transporters family signature. 216591006818 Metal binding protein TroA_a. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and...; Region: TroA_a; cd01148 216591006819 proposed F420-0 ABC transporter, periplasmic F420-0 binding protein; Region: F420-O_ABCperi; TIGR03868 216591006820 putative ligand binding residues [chemical binding]; other site 216591006821 HMMPfam hit to PF01497, Periplasmic binding protein, score 1.2e-06 216591006822 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 216591006823 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 216591006824 ABC-ATPase subunit interface; other site 216591006825 dimer interface [polypeptide binding]; other site 216591006826 putative PBP binding regions; other site 216591006827 10 probable transmembrane helices predicted for BCAL1348 by TMHMM2.0 at aa 12-34, 44-66, 78-100, 110-132, 134-156, 166-188, 195-217, 259-281, 294-316 and 326-343 216591006828 HMMPfam hit to PF01032, FecCD transport family, score 2.2e-64 216591006829 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006830 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591006831 dimerization interface [polypeptide binding]; other site 216591006832 His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512 216591006833 dimer interface [polypeptide binding]; other site 216591006834 phosphorylation site [posttranslational modification] 216591006835 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591006836 ATP binding site [chemical binding]; other site 216591006837 Mg2+ binding site [ion binding]; other site 216591006838 G-X-G motif; other site 216591006839 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2.9e-33 216591006840 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.8e-12 216591006841 HMMPfam hit to PF00672, HAMP domain, score 2.1e-11 216591006842 2 probable transmembrane helices predicted for BCAL1349 by TMHMM2.0 at aa 5-27 and 135-157 216591006843 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591006844 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591006845 active site 216591006846 phosphorylation site [posttranslational modification] 216591006847 intermolecular recognition site; other site 216591006848 dimerization interface [polypeptide binding]; other site 216591006849 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591006850 DNA binding site [nucleotide binding] 216591006851 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 4e-20 216591006852 HMMPfam hit to PF00072, Response regulator receiver domain, score 3e-33 216591006853 MltA-interacting protein MipA; Region: MipA; cl01504 216591006854 HMMPfam hit to PF06629, MltA-interacting protein MipA, score 9.5e-44 216591006855 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006856 3-oxoacyl-(acyl carrier protein) synthase; Validated; Region: PRK06147 216591006857 2 probable transmembrane helices predicted for BCAL1353 by TMHMM2.0 at aa 5-22 and 34-53 216591006858 PAAR motif; Region: PAAR_motif; pfam05488 216591006859 HMMPfam hit to PF05488, PAAR motif, score 0.075 216591006860 PS00430 TonB-dependent receptor proteins signature 1. 216591006861 HMMPfam hit to PF05488, PAAR motif, score 0.0017 216591006862 Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501 216591006863 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 216591006864 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 216591006865 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 216591006866 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 216591006867 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 5.7e-26 216591006868 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591006869 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 216591006870 Protein of unknown function (DUF3304); Region: DUF3304; pfam11745 216591006871 Uncharacterized conserved protein (DUF2235); Region: DUF2235; cl01480 216591006872 Uncharacterized conserved protein (DUF2235); Region: DUF2235; cl01480 216591006873 Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501 216591006874 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 216591006875 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 216591006876 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 216591006877 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 216591006878 Immune inhibitor A peptidase M6; Region: Peptidase_M6; cl11525 216591006879 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 1.2e-13 216591006880 Fibronectin type III-like domain; Region: Fn3-like; pfam14310 216591006881 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 216591006882 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 216591006883 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 216591006884 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 216591006885 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733 216591006886 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 3.5e-09 216591006887 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 216591006888 Protein of unknown function (DUF1365); Region: DUF1365; cl17838 216591006889 Protein of unknown function (DUF805); Region: DUF805; pfam05656 216591006890 HMMPfam hit to PF05656, Protein of unknown function (DUF805), score 3.4e-06 216591006891 2 probable transmembrane helices predicted for BCAL1364 by TMHMM2.0 at aa 24-46 and 59-81 216591006892 Protein of unknown function (DUF3304); Region: DUF3304; pfam11745 216591006893 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591006894 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006895 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006896 Uncharacterized conserved protein (DUF2235); Region: DUF2235; cl01480 216591006897 Uncharacterized conserved protein (DUF2235); Region: DUF2235; cl01480 216591006898 PS00559 Eukaryotic molybdopterin oxidoreductases signature. 216591006899 PS00904 Protein prenyltransferases alpha subunit repeat signature. 216591006900 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 216591006901 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591006902 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591006903 catalytic residue [active] 216591006904 VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911 216591006905 VirB7 interaction site; other site 216591006906 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 6.6e-26 216591006907 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006908 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591006909 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591006910 trimer interface [polypeptide binding]; other site 216591006911 eyelet of channel; other site 216591006912 HMMPfam hit to PF00267, Gram-negative porin, score 2.5e-06 216591006913 RNA polymerase sigma factor; Provisional; Region: PRK12528 216591006914 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591006915 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591006916 DNA binding residues [nucleotide binding] 216591006917 HMMPfam hit to PF04542, Sigma-70 region, score 2.3e-13 216591006918 HMMPfam hit to PF08281, Sigma-70, region, score 2.6e-16 216591006919 HMMPfam hit to PF04545, Sigma-70, region, score 2.2e-08 216591006920 Predicted helix-turn-helix motif with score 2086.000, SD 6.29 at aa 136-157, sequence LTQAEIARELGVSLATVKRYLV 216591006921 fec operon regulator FecR; Reviewed; Region: PRK09774 216591006922 FecR protein; Region: FecR; pfam04773 216591006923 HMMPfam hit to PF04773, FecR protein, score 6.7e-40 216591006924 Secretin and TonB N terminus short domain; Region: STN; smart00965 216591006925 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 216591006926 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591006927 N-terminal plug; other site 216591006928 ligand-binding site [chemical binding]; other site 216591006929 HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 5.6e-09 216591006930 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.5e-17 216591006931 HMMPfam hit to PF00593, TonB dependent receptor, score 5.8e-29 216591006932 1 probable transmembrane helix predicted for BCAL1372 by TMHMM2.0 at aa 13-35 216591006933 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591006934 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591006935 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_2; cd08427 216591006936 putative dimerization interface [polypeptide binding]; other site 216591006937 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.6e-39 216591006938 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.2e-17 216591006939 PS00044 Bacterial regulatory proteins, lysR family signature. 216591006940 Predicted helix-turn-helix motif with score 1159.000, SD 3.13 at aa 15-36, sequence GTFAAAGNRIGLTQAAVSAQMQ 216591006941 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_18; cd08357 216591006942 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591006943 putative metal binding site [ion binding]; other site 216591006944 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 4.5e-08 216591006945 Flavin reductase like domain; Region: Flavin_Reduct; smart00903 216591006946 HMMPfam hit to PF01613, Flavin reductase like domain, score 2.9e-06 216591006947 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006948 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591006949 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591006950 TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440 216591006951 putative dimerization interface [polypeptide binding]; other site 216591006952 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.4e-51 216591006953 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3e-21 216591006954 PS00044 Bacterial regulatory proteins, lysR family signature. 216591006955 Predicted helix-turn-helix motif with score 1557.000, SD 4.49 at aa 18-39, sequence GNFTRAAARLHLSQPALTVQIR 216591006956 H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851 216591006957 Citrate transporter; Region: CitMHS; pfam03600 216591006958 HMMPfam hit to PF03606, C4-dicarboxylate anaerobic carrier, score 0.0023 216591006959 13 probable transmembrane helices predicted for BCAL1377 by TMHMM2.0 at aa 2-19, 23-45, 52-74, 104-126, 139-161, 176-195, 230-249, 253-270, 282-304, 314-336, 349-371, 386-405 and 412-431 216591006960 HMMPfam hit to PF03600, Citrate transporter, score 1.6e-96 216591006961 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591006962 Protein of unknown function (DUF1446); Region: DUF1446; pfam07287 216591006963 HMMPfam hit to PF07287, Protein of unknown function (DUF1446), score 4.4e-107 216591006964 PS00017 ATP/GTP-binding site motif A (P-loop). 216591006965 Predicted amidohydrolase [General function prediction only]; Region: COG0388 216591006966 Pseudomonas sp. MCI3434 R-amidase and related proteins (putative class 13 nitrilases); Region: R-amidase_like; cd07576 216591006967 putative active site [active] 216591006968 catalytic triad [active] 216591006969 putative dimer interface [polypeptide binding]; other site 216591006970 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 1.6e-37 216591006971 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591006972 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591006973 DNA binding residues [nucleotide binding] 216591006974 dimerization interface [polypeptide binding]; other site 216591006975 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 1.8e-20 216591006976 PS00622 Bacterial regulatory proteins, luxR family signature. 216591006977 Predicted helix-turn-helix motif with score 1308.000, SD 3.64 at aa 219-240, sequence RSNKEVASKLDISAETVKVHRR 216591006978 1 probable transmembrane helix predicted for BCAL1382 by TMHMM2.0 at aa 13-35 216591006979 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589 216591006980 CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575 216591006981 HMMPfam hit to PF01148, Cytidylyltransferase family, score 1.8e-72 216591006982 8 probable transmembrane helices predicted for BCAL1383 by TMHMM2.0 at aa 5-27, 50-72, 93-115, 119-136, 149-168, 178-200, 220-239 and 243-265 216591006983 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204 216591006984 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 216591006985 putative acyl-acceptor binding pocket; other site 216591006986 HMMPfam hit to PF01553, Acyltransferase, score 3e-08 216591006987 Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558 216591006988 4 probable transmembrane helices predicted for BCAL1385 by TMHMM2.0 at aa 43-65, 86-108, 118-140 and 153-175 216591006989 HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 3.4e-06 216591006990 Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267 216591006991 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591006992 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591006993 S-adenosylmethionine binding site [chemical binding]; other site 216591006994 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 0.00016 216591006995 PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386 216591006996 active site 216591006997 8 probable transmembrane helices predicted for BCAL1387 by TMHMM2.0 at aa 26-48, 68-90, 103-121, 146-165, 170-192, 196-215, 258-280 and 295-317 216591006998 HMMPfam hit to PF00782, Dual specificity phosphatase, catalytic doma, score 2.9e-07 216591006999 3 probable transmembrane helices predicted for BCAL1388 by TMHMM2.0 at aa 21-40, 45-67 and 123-145 216591007000 cellulose synthase regulator protein; Provisional; Region: PRK11114 216591007001 2 probable transmembrane helices predicted for BCAL1389 by TMHMM2.0 at aa 26-48 and 767-789 216591007002 HMMPfam hit to PF03170, Bacterial cellulose synthase subunit, score 1.3e-131 216591007003 endo-1,4-D-glucanase; Provisional; Region: PRK11097 216591007004 HMMPfam hit to PF01270, Glycosyl hydrolases family, score 7.2e-57 216591007005 PS00812 Glycosyl hydrolases family 8 signature. 216591007006 Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420 216591007007 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.13 216591007008 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 0.23 216591007009 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.13 216591007010 HMMPfam hit to PF05420, Cellulose synthase operon protein C C-termin, score 3.2e-86 216591007011 cellulose biosynthesis protein BcsE; Region: cellulose_bcsE; TIGR03369 216591007012 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007013 1 probable transmembrane helix predicted for BCAL1393 by TMHMM2.0 at aa 5-27 216591007014 cellulose synthase operon protein YhjQ; Region: cellulose_yhjQ; TIGR03371 216591007015 cellulose synthase catalytic subunit (UDP-forming); Region: CelA; TIGR03030 216591007016 CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421 216591007017 DXD motif; other site 216591007018 PilZ domain; Region: PilZ; pfam07238 216591007019 9 probable transmembrane helices predicted for BCAL1395 by TMHMM2.0 at aa 148-165, 169-188, 195-213, 228-250, 526-548, 552-574, 586-608, 638-657 and 664-686 216591007020 HMMPfam hit to PF00535, Glycosyl transferase family, score 1.6e-23 216591007021 HMMPfam hit to PF07238, PilZ domain, score 2.2e-21 216591007022 Protein of unknown function (DUF3260); Region: DUF3260; cl11881 216591007023 cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368 216591007024 4 probable transmembrane helices predicted for BCAL1396 by TMHMM2.0 at aa 20-38, 45-62, 91-113 and 120-142 216591007025 PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 216591007026 Pirin-related protein [General function prediction only]; Region: COG1741 216591007027 Pirin; Region: Pirin; pfam02678 216591007028 Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726 216591007029 HMMPfam hit to PF05726, Pirin C-terminal cupin domain, score 7.7e-24 216591007030 HMMPfam hit to PF02678, Pirin, score 6.7e-54 216591007031 Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765 216591007032 HMMPfam hit to PF02566, OsmC-like protein, score 6.6e-34 216591007033 NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025 216591007034 10 probable transmembrane helices predicted for BCAL1400 by TMHMM2.0 at aa 7-29, 56-75, 82-104, 153-175, 182-204, 228-250, 270-292, 307-329, 350-372 and 382-404 216591007035 HMMPfam hit to PF00999, Sodium/hydrogen exchanger family, score 5.9e-51 216591007036 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007037 Protein of unknown function (DUF1427); Region: DUF1427; pfam07235 216591007038 HMMPfam hit to PF07235, Protein of unknown function (DUF1427), score 2.5e-39 216591007039 2 probable transmembrane helices predicted for BCAL1401 by TMHMM2.0 at aa 5-22 and 27-49 216591007040 YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012 216591007041 Isochorismatase family; Region: Isochorismatase; pfam00857 216591007042 catalytic triad [active] 216591007043 dimer interface [polypeptide binding]; other site 216591007044 conserved cis-peptide bond; other site 216591007045 HMMPfam hit to PF00857, Isochorismatase family, score 1.4e-05 216591007046 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591007047 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591007048 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591007049 putative effector binding pocket; other site 216591007050 dimerization interface [polypeptide binding]; other site 216591007051 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.6e-47 216591007052 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3e-21 216591007053 PS00044 Bacterial regulatory proteins, lysR family signature. 216591007054 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fami, score 0.0035 216591007055 Predicted helix-turn-helix motif with score 2291.000, SD 6.99 at aa 20-41, sequence GSFAKAADLLGVSQPTVSKAIA 216591007056 Protein of unknown function (DUF1427); Region: DUF1427; pfam07235 216591007057 2 probable transmembrane helices predicted for BCAL1403A by TMHMM2.0 at aa 4-23 and 30-52 216591007058 Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574 216591007059 YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300 216591007060 active site 216591007061 HMMPfam hit to PF07969, Amidohydrolase family, score 2.3e-148 216591007062 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007063 Predicted membrane protein [Function unknown]; Region: COG2259 216591007064 4 probable transmembrane helices predicted for BCAL1405 by TMHMM2.0 at aa 20-42, 62-84, 86-105 and 115-137 216591007065 HMMPfam hit to PF07681, DoxX, score 4.7e-17 216591007066 1 probable transmembrane helix predicted for BCAL1406 by TMHMM2.0 at aa 7-25 216591007067 Protein of unknown function (DUF1275); Region: DUF1275; pfam06912 216591007068 HMMPfam hit to PF06912, Protein of unknown function (DUF1275), score 2.2e-28 216591007069 5 probable transmembrane helices predicted for BCAL1407 by TMHMM2.0 at aa 7-29, 39-61, 74-96, 170-188 and 193-215 216591007070 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007071 Domain of unknown function (DUF4104); Region: DUF4104; pfam13372 216591007072 Phospholipase C [Cell envelope biogenesis, outer membrane]; Region: PlcC; COG3511 216591007073 acid phosphatase, Burkholderia-type; Region: acid_phos_Burk; TIGR03397 216591007074 HMMPfam hit to PF04185, Phosphoesterase family, score 6e-164 216591007075 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 216591007076 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007077 Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150 216591007078 1 probable transmembrane helix predicted for BCAL1410 by TMHMM2.0 at aa 17-39 216591007079 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007080 HMMPfam hit to PF03150, Di-haem cytochrome c peroxidase, score 2.4e-20 216591007081 PS00190 Cytochrome c family heme-binding site signature. 216591007082 PS00190 Cytochrome c family heme-binding site signature. 216591007083 Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883 216591007084 nudix motif; other site 216591007085 HMMPfam hit to PF00293, NUDIX domain, score 3.5e-18 216591007086 PS00893 mutT domain signature. 216591007087 glutaminyl-tRNA synthetase; Provisional; Region: PRK05347 216591007088 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 216591007089 active site 216591007090 HIGH motif; other site 216591007091 nucleotide binding site [chemical binding]; other site 216591007092 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 216591007093 active site 216591007094 KMSKS motif; other site 216591007095 tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950 216591007096 HMMPfam hit to PF03950, tRNA synthetases class I (E and Q), an, score 1.8e-71 216591007097 HMMPfam hit to PF00749, tRNA synthetases class I (E and Q), ca, score 1.3e-134 216591007098 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591007099 2 probable transmembrane helices predicted for BCAL1413A by TMHMM2.0 at aa 7-29 and 44-66 216591007100 Serine hydrolase; Region: Ser_hydrolase; pfam06821 216591007101 HMMPfam hit to PF06821, Alpha/Beta hydrolase family of unknown funct, score 6.1e-62 216591007102 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591007103 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591007104 HMMPfam hit to PF02515, CoA-transferase family III, score 9.3e-84 216591007105 alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252 216591007106 Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673 216591007107 motif 1; other site 216591007108 active site 216591007109 motif 2; other site 216591007110 motif 3; other site 216591007111 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863 216591007112 DHHA1 domain; Region: DHHA1; pfam02272 216591007113 HMMPfam hit to PF01411, tRNA synthetases class II (A), score 0 216591007114 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591007115 HMMPfam hit to PF07973, Threonyl and Alanyl tRNA synthetase seco, score 3.3e-18 216591007116 PS00087 Copper/Zinc superoxide dismutase signature 1. 216591007117 HMMPfam hit to PF02272, DHHA1 domain, score 1.7e-19 216591007118 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591007119 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591007120 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591007121 dimerization interface [polypeptide binding]; other site 216591007122 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.7e-50 216591007123 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.7e-19 216591007124 PS00044 Bacterial regulatory proteins, lysR family signature. 216591007125 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591007126 putative substrate translocation pore; other site 216591007127 12 probable transmembrane helices predicted for BCAL1418 by TMHMM2.0 at aa 26-45, 65-87, 94-112, 116-138, 150-172, 176-198, 241-263, 278-297, 304-323, 328-347, 360-382 and 392-414 216591007128 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.7e-10 216591007129 HMMPfam hit to PF06779, Protein of unknown function (DUF1228), score 8.3e-27 216591007130 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007131 NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297 216591007132 Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447 216591007133 nudix motif; other site 216591007134 HMMPfam hit to PF00293, NUDIX domain, score 2.1e-17 216591007135 PS00893 mutT domain signature. 216591007136 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 216591007137 active site 216591007138 1 probable transmembrane helix predicted for BCAL1420 by TMHMM2.0 at aa 7-26 216591007139 HMMPfam hit to PF03061, Thioesterase superfamily, score 2.3e-15 216591007140 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 216591007141 TM-ABC transporter signature motif; other site 216591007142 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 6e-10 216591007143 7 probable transmembrane helices predicted for BCAL1421 by TMHMM2.0 at aa 9-31, 51-73, 94-116, 142-159, 191-213, 223-245 and 276-298 216591007144 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007145 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 216591007146 ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177 216591007147 TM-ABC transporter signature motif; other site 216591007148 9 probable transmembrane helices predicted for BCAL1422 by TMHMM2.0 at aa 15-37, 44-66, 86-108, 115-137, 157-179, 251-273, 288-310, 330-352 and 372-394 216591007149 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.6e-19 216591007150 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 216591007151 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 216591007152 Walker A/P-loop; other site 216591007153 ATP binding site [chemical binding]; other site 216591007154 Q-loop/lid; other site 216591007155 ABC transporter signature motif; other site 216591007156 Walker B; other site 216591007157 D-loop; other site 216591007158 H-loop/switch region; other site 216591007159 HMMPfam hit to PF00005, ABC transporter, score 2.2e-43 216591007160 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007161 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 216591007162 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 216591007163 Walker A/P-loop; other site 216591007164 ATP binding site [chemical binding]; other site 216591007165 Q-loop/lid; other site 216591007166 ABC transporter signature motif; other site 216591007167 Walker B; other site 216591007168 D-loop; other site 216591007169 H-loop/switch region; other site 216591007170 HMMPfam hit to PF00005, ABC transporter, score 4.5e-42 216591007171 PS00211 ABC transporters family signature. 216591007172 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231 216591007173 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591007174 NAD(P) binding site [chemical binding]; other site 216591007175 active site 216591007176 HMMPfam hit to PF00106, short chain dehydrogenase, score 9e-31 216591007177 PS00061 Short-chain dehydrogenases/reductases family signature. 216591007178 hypothetical protein; Provisional; Region: PRK02487 216591007179 HMMPfam hit to PF03928, Domain of unknown function (DUF336), score 1.2e-21 216591007180 Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718 216591007181 HMMPfam hit to PF06845, Myo-inositol catabolism protein IolB, score 4e-170 216591007182 Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082 216591007183 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 2.1e-43 216591007184 Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962 216591007185 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 216591007186 dimer interface [polypeptide binding]; other site 216591007187 PYR/PP interface [polypeptide binding]; other site 216591007188 TPP binding site [chemical binding]; other site 216591007189 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591007190 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629 216591007191 TPP-binding site [chemical binding]; other site 216591007192 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 9.4e-42 216591007193 PS00187 Thiamine pyrophosphate enzymes signature. 216591007194 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 3.1e-34 216591007195 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 1.9e-06 216591007196 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 216591007197 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166 216591007198 substrate binding site [chemical binding]; other site 216591007199 ATP binding site [chemical binding]; other site 216591007200 Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863 216591007201 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892 216591007202 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591007203 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 3.8e-42 216591007204 PS00584 pfkB family of carbohydrate kinases signature 2. 216591007205 Periplasmic binding proteins specific to rhizopines; Region: PBP1_rhizopine_binding_like; cd06301 216591007206 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 216591007207 putative ligand binding site [chemical binding]; other site 216591007208 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 3.4e-07 216591007209 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 216591007210 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 216591007211 Walker A/P-loop; other site 216591007212 ATP binding site [chemical binding]; other site 216591007213 Q-loop/lid; other site 216591007214 ABC transporter signature motif; other site 216591007215 Walker B; other site 216591007216 D-loop; other site 216591007217 H-loop/switch region; other site 216591007218 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 216591007219 HMMPfam hit to PF00005, ABC transporter, score 2.4e-48 216591007220 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007221 HMMPfam hit to PF00005, ABC transporter, score 3.5e-24 216591007222 PS00211 ABC transporters family signature. 216591007223 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591007224 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591007225 TM-ABC transporter signature motif; other site 216591007226 8 probable transmembrane helices predicted for BCAL1433 by TMHMM2.0 at aa 26-48, 58-80, 87-106, 121-143, 150-168, 183-205, 236-258 and 290-312 216591007227 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 8.9e-63 216591007228 Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082 216591007229 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 1.3e-42 216591007230 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 216591007231 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 216591007232 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 216591007233 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007234 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 2.1e-31 216591007235 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 2.4e-13 216591007236 Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082 216591007237 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 1.5e-41 216591007238 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 216591007239 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 216591007240 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 216591007241 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 2.2e-39 216591007242 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 5.2e-10 216591007243 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 216591007244 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 216591007245 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 216591007246 putative active site [active] 216591007247 HMMPfam hit to PF01418, Helix-turn-helix domain, rpiR family, score 3.7e-05 216591007248 Predicted helix-turn-helix motif with score 1166.000, SD 3.16 at aa 71-92, sequence EGIQSLAEACGVQPSAVVRFAK 216591007249 HMMPfam hit to PF01380, SIS domain, score 1.3e-22 216591007250 Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085 216591007251 methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722 216591007252 tetrameric interface [polypeptide binding]; other site 216591007253 NAD binding site [chemical binding]; other site 216591007254 catalytic residues [active] 216591007255 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 7.6e-174 216591007256 PS00070 Aldehyde dehydrogenases cysteine active site. 216591007257 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591007258 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591007259 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591007260 putative effector binding pocket; other site 216591007261 dimerization interface [polypeptide binding]; other site 216591007262 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.5e-17 216591007263 Predicted helix-turn-helix motif with score 1686.000, SD 4.93 at aa 23-44, sequence GSFTAAAQRLGISKAAMSQRIA 216591007264 PS00044 Bacterial regulatory proteins, lysR family signature. 216591007265 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.5e-44 216591007266 SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291 216591007267 CPxP motif; other site 216591007268 HMMPfam hit to PF01206, SirA-like protein, score 1.3e-19 216591007269 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591007270 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591007271 active site 216591007272 phosphorylation site [posttranslational modification] 216591007273 intermolecular recognition site; other site 216591007274 dimerization interface [polypeptide binding]; other site 216591007275 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591007276 DNA binding site [nucleotide binding] 216591007277 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.5e-26 216591007278 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.5e-16 216591007279 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4254 216591007280 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 216591007281 FecR protein; Region: FecR; pfam04773 216591007282 HMMPfam hit to PF01476, LysM domain, score 1.9e-06 216591007283 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 216591007284 Predicted transmembrane sensor domain [Signal transduction mechanisms]; Region: COG4252 216591007285 CHASE2 domain; Region: CHASE2; pfam05226 216591007286 PAS domain; Region: PAS_9; pfam13426 216591007287 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591007288 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591007289 dimer interface [polypeptide binding]; other site 216591007290 phosphorylation site [posttranslational modification] 216591007291 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591007292 ATP binding site [chemical binding]; other site 216591007293 Mg2+ binding site [ion binding]; other site 216591007294 G-X-G motif; other site 216591007295 4 probable transmembrane helices predicted for BCAL1445 by TMHMM2.0 at aa 20-42, 307-326, 330-352 and 357-376 216591007296 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007297 HMMPfam hit to PF05226, CHASE2 domain, score 7.6e-50 216591007298 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.00057 216591007299 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3.6e-33 216591007300 Domain of unknown function (DUF4136); Region: DUF4136; pfam13590 216591007301 1 probable transmembrane helix predicted for BCAL1446 by TMHMM2.0 at aa 7-29 216591007302 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007303 Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541 216591007304 dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209 216591007305 active site 216591007306 tetramer interface; other site 216591007307 HMMPfam hit to PF00483, Nucleotidyl transferase, score 4.3e-17 216591007308 valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729 216591007309 catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817 216591007310 HIGH motif; other site 216591007311 Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603 216591007312 catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817 216591007313 active site 216591007314 KMSKS motif; other site 216591007315 Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962 216591007316 tRNA binding surface [nucleotide binding]; other site 216591007317 anticodon binding site; other site 216591007318 Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458 216591007319 HMMPfam hit to PF08264, Anticodon-binding domain, score 1.6e-54 216591007320 HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 0 216591007321 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007322 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591007323 DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773 216591007324 Part of AAA domain; Region: AAA_19; pfam13245 216591007325 Family description; Region: UvrD_C_2; pfam13538 216591007326 HMMPfam hit to PF00580, UvrD/REP helicase, score 1.5e-189 216591007327 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007328 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584 216591007329 HMMPfam hit to PF01048, Phosphorylase family, score 1.8e-33 216591007330 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591007331 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591007332 putative substrate translocation pore; other site 216591007333 11 probable transmembrane helices predicted for BCAL1451 by TMHMM2.0 at aa 29-51, 58-80, 100-134, 155-177, 182-204, 225-247, 267-289, 296-318, 322-343, 350-372 and 382-404 216591007334 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.7e-43 216591007335 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007336 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 216591007337 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591007338 dimer interface [polypeptide binding]; other site 216591007339 putative CheW interface [polypeptide binding]; other site 216591007340 2 probable transmembrane helices predicted for BCAL1452 by TMHMM2.0 at aa 4-21 and 180-202 216591007341 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 6e-93 216591007342 p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559 216591007343 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591007344 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591007345 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.9e-25 216591007346 1 probable transmembrane helix predicted for BCAL1453 by TMHMM2.0 at aa 7-29 216591007347 Protein of unknown function (DUF1656); Region: DUF1656; pfam07869 216591007348 2 probable transmembrane helices predicted for BCAL1454 by TMHMM2.0 at aa 7-29 and 44-66 216591007349 HMMPfam hit to PF07869, Protein of unknown function (DUF1656), score 1.8e-21 216591007350 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591007351 Fusaric acid resistance protein family; Region: FUSC; pfam04632 216591007352 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 216591007353 10 probable transmembrane helices predicted for BCAL1455 by TMHMM2.0 at aa 31-53, 80-102, 107-124, 131-148, 163-182, 393-415, 445-467, 474-493, 498-520 and 532-554 216591007354 HMMPfam hit to PF04632, Fusaric acid resistance protein conserved re, score 1.4e-52 216591007355 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591007356 HMMPfam hit to PF02321, Outer membrane efflux protein, score 4.6e-37 216591007357 PS00216 Sugar transport proteins signature 1. 216591007358 HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.2e-29 216591007359 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007360 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591007361 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591007362 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591007363 putative effector binding pocket; other site 216591007364 dimerization interface [polypeptide binding]; other site 216591007365 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.9e-18 216591007366 Predicted helix-turn-helix motif with score 1117.000, SD 2.99 at aa 17-38, sequence GSFTAAAQQMNSTTAYASRAVS 216591007367 HMMPfam hit to PF03466, LysR substrate binding domain, score 1e-49 216591007368 1 probable transmembrane helix predicted for BCAL1458 by TMHMM2.0 at aa 4-26 216591007369 Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409 216591007370 Microscilla MS158 and related proteins, metallophosphatase domain; Region: MPP_MS158; cd07404 216591007371 putative active site [active] 216591007372 putative metal binding site [ion binding]; other site 216591007373 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1.1e-15 216591007374 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007375 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 216591007376 FAD binding domain; Region: FAD_binding_4; pfam01565 216591007377 HMMPfam hit to PF02913, FAD linked oxidases, C-terminal domain, score 1.8e-66 216591007378 HMMPfam hit to PF01565, FAD binding domain, score 1.8e-40 216591007379 Predicted membrane protein (DUF2069); Region: DUF2069; pfam09842 216591007380 3 probable transmembrane helices predicted for BCAL1461 by TMHMM2.0 at aa 15-37, 66-85 and 95-117 216591007381 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 216591007382 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591007383 HMMPfam hit to PF00258, Flavodoxin, score 0.00043 216591007384 PS00201 Flavodoxin signature. 216591007385 Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918 216591007386 HMMPfam hit to PF03631, Ribonuclease BN-like family, score 1e-54 216591007387 5 probable transmembrane helices predicted for BCAL1463 by TMHMM2.0 at aa 27-49, 99-121, 134-156, 176-198 and 238-260 216591007388 Protein of unknown function (DUF962); Region: DUF962; cl01879 216591007389 2 probable transmembrane helices predicted for BCAL1464 by TMHMM2.0 at aa 31-48 and 52-74 216591007390 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007391 FOG: CBS domain [General function prediction only]; Region: COG0517 216591007392 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354 216591007393 HMMPfam hit to PF00571, CBS domain pair, score 1.3e-25 216591007394 H+ Antiporter protein; Region: 2A0121; TIGR00900 216591007395 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204 216591007396 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 216591007397 putative acyl-acceptor binding pocket; other site 216591007398 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.6e-15 216591007399 8 probable transmembrane helices predicted for BCAL1466 by TMHMM2.0 at aa 71-93, 108-130, 246-268, 281-300, 313-335, 355-377, 389-411 and 431-453 216591007400 HMMPfam hit to PF01553, Acyltransferase, score 3.3e-28 216591007401 Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082 216591007402 Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304 216591007403 Tetramer interface [polypeptide binding]; other site 216591007404 active site 216591007405 FMN-binding site [chemical binding]; other site 216591007406 HMMPfam hit to PF01264, Chorismate synthase, score 8.4e-195 216591007407 PS00787 Chorismate synthase signature 1. 216591007408 PS00789 Chorismate synthase signature 3. 216591007409 Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644 216591007410 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 216591007411 Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187 216591007412 Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440 216591007413 HMMPfam hit to PF05187, Electron transfer flavoprotein-ubiquinone ox, score 6.5e-116 216591007414 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00011 216591007415 short chain dehydrogenase; Provisional; Region: PRK06949 216591007416 classical (c) SDRs; Region: SDR_c; cd05233 216591007417 NAD(P) binding site [chemical binding]; other site 216591007418 active site 216591007419 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.7e-34 216591007420 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0028 216591007421 PS00061 Short-chain dehydrogenases/reductases family signature. 216591007422 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 216591007423 active site 216591007424 HMMPfam hit to PF03061, Thioesterase superfamily, score 4.8e-10 216591007425 PAS domain; Region: PAS_9; pfam13426 216591007426 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591007427 putative active site [active] 216591007428 heme pocket [chemical binding]; other site 216591007429 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591007430 DNA binding residues [nucleotide binding] 216591007431 dimerization interface [polypeptide binding]; other site 216591007432 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 4.3e-18 216591007433 PS00622 Bacterial regulatory proteins, luxR family signature. 216591007434 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007435 HMMPfam hit to PF08448, PAS fold, score 1.9e-06 216591007436 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788 216591007437 HMMPfam hit to PF01144, Coenzyme A transferase, score 4.2e-105 216591007438 PS01273 CoA transferases signature 1. 216591007439 3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428 216591007440 HMMPfam hit to PF01144, Coenzyme A transferase, score 7e-56 216591007441 PS01274 CoA transferases signature 2. 216591007442 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591007443 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028 216591007444 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591007445 NAD(P) binding site [chemical binding]; other site 216591007446 active site 216591007447 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 3.5e-05 216591007448 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.3e-08 216591007449 Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692 216591007450 putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212 216591007451 HMMPfam hit to PF01522, Polysaccharide deacetylase, score 2.8e-18 216591007452 SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366 216591007453 HMMPfam hit to PF07366, SnoaL-like polyketide cyclase, score 5.3e-52 216591007454 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007455 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591007456 transcriptional activator TtdR; Provisional; Region: PRK09801 216591007457 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591007458 putative effector binding pocket; other site 216591007459 dimerization interface [polypeptide binding]; other site 216591007460 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.5e-12 216591007461 Predicted helix-turn-helix motif with score 1370.000, SD 3.85 at aa 20-41, sequence GSLSAAARELDLSLSVVSKRLT 216591007462 PS00044 Bacterial regulatory proteins, lysR family signature. 216591007463 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.4e-53 216591007464 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591007465 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591007466 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 5.1e-05 216591007467 This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150 216591007468 homotrimer interaction site [polypeptide binding]; other site 216591007469 putative active site [active] 216591007470 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 4.8e-24 216591007471 PS01094 Uncharacterized protein family UPF0076 signature. 216591007472 Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317 216591007473 HD domain; Region: HD_4; pfam13328 216591007474 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 216591007475 synthetase active site [active] 216591007476 NTP binding site [chemical binding]; other site 216591007477 metal binding site [ion binding]; metal-binding site 216591007478 TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668 216591007479 ACT domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876 216591007480 HMMPfam hit to PF04607, Region found in RelA / SpoT proteins, score 1.2e-49 216591007481 HMMPfam hit to PF02824, TGS domain, score 1e-24 216591007482 HMMPfam hit to PF01842, ACT domain, score 2.3e-08 216591007483 threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413 216591007484 TGS _ThrRS_N: ThrRS (threonyl-tRNA Synthetase) is a class II tRNA synthetase that couples threonine to its cognate tRNA. In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667 216591007485 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863 216591007486 Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771 216591007487 active site 216591007488 dimer interface [polypeptide binding]; other site 216591007489 motif 1; other site 216591007490 motif 2; other site 216591007491 motif 3; other site 216591007492 ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860 216591007493 anticodon binding site; other site 216591007494 HMMPfam hit to PF02824, TGS domain, score 1.4e-10 216591007495 HMMPfam hit to PF07973, Threonyl and Alanyl tRNA synthetase se, score 2.5e-27 216591007496 HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 3.6e-63 216591007497 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591007498 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591007499 HMMPfam hit to PF03129, Anticodon binding domain, score 2.7e-25 216591007500 CDS does not contain a standard translation start codon, possible AGG start codon. Similar to Escherichia coli translation initiation factor IF-3 InfC UniProt:P0A707 (EMBL:AP009048 (180 aa) fasta scores: E()=1.6e-39, 70.238% id in 168 aa, and to Burkholderia pseudomallei (pseudomonas pseudomallei) iranslation initiation factor IF-3 InfC UniProt:Q63TM3 (EMBL:BX571965 (178 aa) fasta scores: E()=1e-59, 94.944% id in 178 aa 216591007501 HMMPfam hit to PF05198, Translation initiation factor IF-3, N-termin, score 7.9e-26 216591007502 PS00938 Initiation factor 3 signature. 216591007503 HMMPfam hit to PF00707, Translation initiation factor IF-3, C-termin, score 7.9e-54 216591007504 50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172 216591007505 HMMPfam hit to PF01632, Ribosomal protein L35, score 1.5e-25 216591007506 Ribosomal protein L20; Region: Ribosomal_L20; cd07026 216591007507 23S rRNA binding site [nucleotide binding]; other site 216591007508 L21 binding site [polypeptide binding]; other site 216591007509 L13 binding site [polypeptide binding]; other site 216591007510 HMMPfam hit to PF00453, Ribosomal protein L20, score 7.5e-58 216591007511 PS00937 Ribosomal protein L20 signature. 216591007512 phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488 216591007513 Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912 216591007514 Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496 216591007515 dimer interface [polypeptide binding]; other site 216591007516 motif 1; other site 216591007517 active site 216591007518 motif 2; other site 216591007519 motif 3; other site 216591007520 HMMPfam hit to PF02912, Aminoacyl tRNA synthetase class II, N, score 6e-27 216591007521 HMMPfam hit to PF01409, tRNA synthetases class II core domain, score 6.3e-141 216591007522 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591007523 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591007524 phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629 216591007525 tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796 216591007526 putative tRNA-binding site [nucleotide binding]; other site 216591007527 B3/4 domain; Region: B3_4; pfam03483 216591007528 tRNA synthetase B5 domain; Region: B5; smart00874 216591007529 Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an...; Region: PheRS_beta_core; cd00769 216591007530 dimer interface [polypeptide binding]; other site 216591007531 motif 1; other site 216591007532 motif 3; other site 216591007533 motif 2; other site 216591007534 Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147 216591007535 HMMPfam hit to PF01588, Putative tRNA binding domain, score 4e-36 216591007536 HMMPfam hit to PF03483, B3/4 domain, score 3.8e-92 216591007537 HMMPfam hit to PF03484, tRNA synthetase B5 domain, score 8.4e-31 216591007538 HMMPfam hit to PF03147, Ferredoxin-fold anticodon binding domain, score 5.5e-19 216591007539 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 216591007540 IHF dimer interface [polypeptide binding]; other site 216591007541 IHF - DNA interface [nucleotide binding]; other site 216591007542 HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 3.7e-47 216591007543 PS00045 Bacterial histone-like DNA-binding proteins signature. 216591007544 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 216591007545 Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765 216591007546 DNA binding residues [nucleotide binding] 216591007547 Predicted helix-turn-helix motif with score 1686.000, SD 4.93 at aa 19-40, sequence FTIGEVSELCGVKPHVLRYWEQ 216591007548 HMMPfam hit to PF00376, MerR family regulatory protein, score 2.1e-11 216591007549 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591007550 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591007551 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591007552 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591007553 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007554 HMMPfam hit to PF01548, Transposase, score 2.9e-12 216591007555 HMMPfam hit to PF05665, Domain of unknown function (DUF811), score 2.5e-44 216591007556 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 216591007557 HMMPfam hit to PF05665, Domain of unknown function (DUF811), score 5.2e-38 216591007558 Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350 216591007559 Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348 216591007560 1 probable transmembrane helix predicted for BCAL1491 by TMHMM2.0 at aa 12-34 216591007561 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007562 Methyltransferase domain; Region: Methyltransf_23; pfam13489 216591007563 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 216591007564 Uncharacterized lipoprotein [Cell envelope biogenesis, outer membrane]; Region: NlpB; COG3317 216591007565 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007566 Uncharacterized conserved protein [Function unknown]; Region: COG1359 216591007567 HMMPfam hit to PF03992, Antibiotic biosynthesis monooxygenase, score 3.6e-21 216591007568 Uncharacterized conserved protein [Function unknown]; Region: COG1434 216591007569 YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259 216591007570 putative active site [active] 216591007571 HMMPfam hit to PF02698, DUF218 domain, score 1.1e-25 216591007572 1 probable transmembrane helix predicted for BCAL1497 by TMHMM2.0 at aa 24-46 216591007573 1 probable transmembrane helix predicted for BCAL1499 by TMHMM2.0 at aa 5-24 216591007574 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 216591007575 Predicted helix-turn-helix motif with score 994.000, SD 2.57 at aa 76-97, sequence GTLAEIVKRLGTSGRQISLRGR 216591007576 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591007577 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591007578 TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440 216591007579 putative dimerization interface [polypeptide binding]; other site 216591007580 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2e-21 216591007581 Predicted helix-turn-helix motif with score 1777.000, SD 5.24 at aa 18-39, sequence RSFSRAGDEIGLTQSAVSRCVR 216591007582 PS00044 Bacterial regulatory proteins, lysR family signature. 216591007583 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.2e-50 216591007584 aspartate aminotransferase; Provisional; Region: PRK06108 216591007585 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591007586 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591007587 homodimer interface [polypeptide binding]; other site 216591007588 catalytic residue [active] 216591007589 HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 0.00058 216591007590 HMMPfam hit to PF00155, Aminotransferase class I and II, score 5.5e-56 216591007591 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 216591007592 Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079 216591007593 HMMPfam hit to PF04079, Putative transcriptional regulators (Ypuh-li, score 4.3e-64 216591007594 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187 216591007595 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 216591007596 RNA binding surface [nucleotide binding]; other site 216591007597 Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556 216591007598 probable active site [active] 216591007599 HMMPfam hit to PF01479, S4 domain, score 8.6e-08 216591007600 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 3.4e-09 216591007601 PS01149 Rsu family of pseudouridine synthase signature. 216591007602 ribosome maturation protein RimP; Reviewed; Region: PRK00092 216591007603 Sm and related proteins; Region: Sm_like; cl00259 216591007604 Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734 216591007605 putative oligomer interface [polypeptide binding]; other site 216591007606 putative RNA binding site [nucleotide binding]; other site 216591007607 HMMPfam hit to PF02576, Uncharacterised BCR, YhbC family COG0779, score 7e-49 216591007608 transcription elongation factor NusA; Validated; Region: nusA; PRK09202 216591007609 NusA N-terminal domain; Region: NusA_N; pfam08529 216591007610 S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455 216591007611 RNA binding site [nucleotide binding]; other site 216591007612 homodimer interface [polypeptide binding]; other site 216591007613 NusA-like KH domain; Region: KH_5; pfam13184 216591007614 NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134 216591007615 G-X-X-G motif; other site 216591007616 transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954 216591007617 transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954 216591007618 HMMPfam hit to PF08529, NusA N-terminal domain, score 4.5e-60 216591007619 HMMPfam hit to PF00575, S1 RNA binding domain, score 9.7e-10 216591007620 Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364 216591007621 translation initiation factor IF-2; Region: IF-2; TIGR00487 216591007622 Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760 216591007623 Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887 216591007624 G1 box; other site 216591007625 putative GEF interaction site [polypeptide binding]; other site 216591007626 GTP/Mg2+ binding site [chemical binding]; other site 216591007627 Switch I region; other site 216591007628 G2 box; other site 216591007629 G3 box; other site 216591007630 Switch II region; other site 216591007631 G4 box; other site 216591007632 G5 box; other site 216591007633 This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702 216591007634 Translation-initiation factor 2; Region: IF-2; pfam11987 216591007635 mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692 216591007636 HMMPfam hit to PF08364, Bacterial translation initiation factor I, score 3.7e-20 216591007637 HMMPfam hit to PF04760, Translation initiation factor IF-2, N-ter, score 8.3e-20 216591007638 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 2.3e-53 216591007639 HMMPfam hit to PF01926, GTPase of unknown function, score 9.9e-07 216591007640 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007641 HMMPfam hit to PF03144, Elongation factor Tu domain, score 2.4e-12 216591007642 HMMPfam hit to PF03144, Elongation factor Tu domain, score 1.4e-08 216591007643 PS01176 Initiation factor 2 signature. 216591007644 ribosome-binding factor A; Validated; Region: rbfA; PRK00521 216591007645 HMMPfam hit to PF02033, Ribosome-binding factor A, score 2.6e-23 216591007646 tRNA pseudouridine synthase B; Provisional; Region: truB; PRK01851 216591007647 Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573 216591007648 RNA binding site [nucleotide binding]; other site 216591007649 active site 216591007650 Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157 216591007651 HMMPfam hit to PF01509, TruB family pseudouridylate synthase (N term, score 6.6e-77 216591007652 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591007653 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591007654 putative substrate translocation pore; other site 216591007655 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591007656 13 probable transmembrane helices predicted for BCAL1510 by TMHMM2.0 at aa 13-32, 54-76, 83-102, 117-136, 143-165, 170-192, 204-223, 233-255, 268-290, 305-327, 339-356, 371-393 and 478-500 216591007657 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.9e-56 216591007658 multidrug efflux system protein EmrA; Provisional; Region: PRK15136 216591007659 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591007660 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591007661 HMMPfam hit to PF00529, HlyD family secretion protein, score 3.7e-77 216591007662 1 probable transmembrane helix predicted for BCAL1511 by TMHMM2.0 at aa 21-43 216591007663 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591007664 HMMPfam hit to PF02321, Outer membrane efflux protein, score 6.6e-37 216591007665 HMMPfam hit to PF02321, Outer membrane efflux protein, score 3.6e-29 216591007666 1 probable transmembrane helix predicted for BCAL1512 by TMHMM2.0 at aa 13-35 216591007667 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007668 Transcriptional regulators [Transcription]; Region: MarR; COG1846 216591007669 MarR family; Region: MarR_2; cl17246 216591007670 HMMPfam hit to PF01047, MarR family, score 1e-19 216591007671 Predicted helix-turn-helix motif with score 1271.000, SD 3.52 at aa 47-68, sequence STAAELAREYGIDASAVTRLLD 216591007672 Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217 216591007673 Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891 216591007674 G1 box; other site 216591007675 putative GEF interaction site [polypeptide binding]; other site 216591007676 GTP/Mg2+ binding site [chemical binding]; other site 216591007677 Switch I region; other site 216591007678 G2 box; other site 216591007679 G3 box; other site 216591007680 Switch II region; other site 216591007681 G4 box; other site 216591007682 G5 box; other site 216591007683 BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu. BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691 216591007684 BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants. BipA is a highly...; Region: BipA_TypA_C; cd03710 216591007685 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 2.2e-68 216591007686 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007687 PS00301 GTP-binding elongation factors signature. 216591007688 HMMPfam hit to PF03144, Elongation factor Tu domain, score 3.4e-09 216591007689 HMMPfam hit to PF00679, Elongation factor G C-terminus, score 9.2e-25 216591007690 2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404 216591007691 Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016 216591007692 TPP-binding site [chemical binding]; other site 216591007693 Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779 216591007694 HMMPfam hit to PF00676, Dehydrogenase E1 component, score 8.5e-37 216591007695 HMMPfam hit to PF02779, Transketolase, pyridine binding domain, score 8.7e-73 216591007696 PS00904 Protein prenyltransferases alpha subunit repeat signature. 216591007697 dihydrolipoamide succinyltransferase; Validated; Region: PRK05704 216591007698 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 216591007699 E3 interaction surface; other site 216591007700 lipoyl attachment site [posttranslational modification]; other site 216591007701 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 216591007702 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 2.5e-29 216591007703 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 216591007704 HMMPfam hit to PF02817, e3 binding domain, score 6e-11 216591007705 HMMPfam hit to PF00198, 2-oxoacid dehydrogenases acyltransferas, score 9.2e-147 216591007706 dihydrolipoamide dehydrogenase; Validated; Region: PRK06327 216591007707 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591007708 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 216591007709 HMMPfam hit to PF00890, FAD binding domain, score 0.00093 216591007710 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 2.9e-73 216591007711 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 216591007712 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 6.6e-31 216591007713 HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 1.4e-57 216591007714 Predicted ATPase [General function prediction only]; Region: COG1485 216591007715 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591007716 Walker B; other site 216591007717 D-loop; other site 216591007718 H-loop/switch region; other site 216591007719 HMMPfam hit to PF03969, AFG1-like ATPase, score 2.4e-156 216591007720 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007721 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 216591007722 Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917 216591007723 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007724 Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831 216591007725 POTRA domain, ShlB-type; Region: POTRA_2; pfam08479 216591007726 Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865 216591007727 HMMPfam hit to PF08479, POTRA domain, ShlB-type, score 2.6e-24 216591007728 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007729 HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.5e-05 216591007730 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007731 Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion]; Region: Flp; COG3847 216591007732 HMMPfam hit to PF04964, Flp/Fap pilin component, score 5.2e-19 216591007733 1 probable transmembrane helix predicted for BCAL1525 by TMHMM2.0 at aa 20-42 216591007734 Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960 216591007735 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989 216591007736 4 probable transmembrane helices predicted for BCAL1525a by TMHMM2.0 at aa 2-19, 50-72, 85-107 and 134-156 216591007737 HMMPfam hit to PF01478, Type IV leader peptidase family, score 1.4e-21 216591007738 Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961 216591007739 TadE-like protein; Region: TadE; pfam07811 216591007740 HMMPfam hit to PF07811, TadE-like protein, score 7.2e-17 216591007741 1 probable transmembrane helix predicted for BCAL1526 by TMHMM2.0 at aa 20-42 216591007742 Flp pilus assembly protein CpaB [Intracellular trafficking and secretion]; Region: CpaB; COG3745 216591007743 SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614 216591007744 1 probable transmembrane helix predicted for BCAL1527 by TMHMM2.0 at aa 5-27 216591007745 HMMPfam hit to PF06981, Flp pilus assembly protein CpaB, score 1.2e-25 216591007746 Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion]; Region: CpaC; COG4964 216591007747 Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629 216591007748 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 216591007749 HMMPfam hit to PF00263, Bacterial type II and III secretion system p, score 3.2e-65 216591007750 FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784 216591007751 AAA domain; Region: AAA_31; pfam13614 216591007752 This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111 216591007753 Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962 216591007754 Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130 216591007755 ATP binding site [chemical binding]; other site 216591007756 Walker A motif; other site 216591007757 hexamer interface [polypeptide binding]; other site 216591007758 Walker B motif; other site 216591007759 HMMPfam hit to PF00437, Type II/IV secretion system protein, score 9e-100 216591007760 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007761 Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965 216591007762 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 216591007763 5 probable transmembrane helices predicted for BCAL1531 by TMHMM2.0 at aa 4-23, 102-119, 123-145, 271-293 and 303-322 216591007764 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 2.3e-14 216591007765 Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064 216591007766 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 216591007767 4 probable transmembrane helices predicted for BCAL1532 by TMHMM2.0 at aa 10-32, 120-142, 152-169 and 304-326 216591007768 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 2.9e-12 216591007769 Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking and secretion]; Region: TadD; COG5010 216591007770 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007771 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.00044 216591007772 Protein of unknown function (DUF3613); Region: DUF3613; pfam12266 216591007773 Putative Flp pilus-assembly TadE/G-like; Region: Tad; pfam13400 216591007774 1 probable transmembrane helix predicted for BCAL1535 by TMHMM2.0 at aa 2-24 216591007775 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007776 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221 216591007777 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591007778 Walker A motif; other site 216591007779 ATP binding site [chemical binding]; other site 216591007780 Walker B motif; other site 216591007781 arginine finger; other site 216591007782 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591007783 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3.8e-107 216591007784 HMMPfam hit to PF07728, ATPase family associated with various, score 0.00045 216591007785 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591007786 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591007787 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591007788 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 3e-10 216591007789 Predicted helix-turn-helix motif with score 1271.000, SD 3.52 at aa 427-448, sequence WRRQDTAQQLGISRKVLWEKMR 216591007790 Protein of unknown function (DUF2968); Region: DUF2968; pfam11180 216591007791 bacterial Hfq-like; Region: Hfq; cd01716 216591007792 hexamer interface [polypeptide binding]; other site 216591007793 Sm1 motif; other site 216591007794 RNA binding site [nucleotide binding]; other site 216591007795 Sm2 motif; other site 216591007796 HMMPfam hit to PF01423, LSM domain, score 7.6e-05 216591007797 2 probable transmembrane helices predicted for BCAL1539 by TMHMM2.0 at aa 7-29 and 44-66 216591007798 Protein of unknown function (DUF1571); Region: DUF1571; pfam07608 216591007799 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974 216591007800 Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936 216591007801 acyl-activating enzyme (AAE) consensus motif; other site 216591007802 putative AMP binding site [chemical binding]; other site 216591007803 putative active site [active] 216591007804 putative CoA binding site [chemical binding]; other site 216591007805 HMMPfam hit to PF00501, AMP-binding enzyme, score 8.3e-132 216591007806 PS00455 Putative AMP-binding domain signature. 216591007807 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591007808 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591007809 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3e-18 216591007810 putative sialic acid transporter; Region: 2A0112; TIGR00891 216591007811 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591007812 putative substrate translocation pore; other site 216591007813 HMMPfam hit to PF00083, Sugar (and other) transporter, score 5.5e-08 216591007814 8 probable transmembrane helices predicted for BCAL1543 by TMHMM2.0 at aa 24-46, 56-78, 99-121, 173-195, 224-241, 261-280, 293-315 and 379-401 216591007815 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 9.9e-38 216591007816 PS00217 Sugar transport proteins signature 2. 216591007817 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 216591007818 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591007819 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.9e-08 216591007820 Putative ParB-like nuclease; Region: ParBc_2; pfam08857 216591007821 Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792 216591007822 Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659 216591007823 Sulfate transporter family; Region: Sulfate_transp; pfam00916 216591007824 Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042 216591007825 HMMPfam hit to PF00860, Permease family, score 0.0024 216591007826 9 probable transmembrane helices predicted for BCAL1546 by TMHMM2.0 at aa 64-86, 106-128, 149-171, 186-208, 213-230, 260-282, 336-353, 363-385 and 392-414 216591007827 HMMPfam hit to PF00916, Sulfate transporter family, score 2.2e-45 216591007828 PS00131 Serine carboxypeptidases, serine active site. 216591007829 HMMPfam hit to PF01740, STAS domain, score 0.0026 216591007830 Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167 216591007831 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 216591007832 putative substrate binding site [chemical binding]; other site 216591007833 putative ATP binding site [chemical binding]; other site 216591007834 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 6.2e-45 216591007835 Predicted helix-turn-helix motif with score 1086.000, SD 2.89 at aa 175-196, sequence RRLTALADWIKVSDEDLRGLFP 216591007836 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007837 Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321 216591007838 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 216591007839 putative ligand binding site [chemical binding]; other site 216591007840 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 2.5e-06 216591007841 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591007842 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591007843 TM-ABC transporter signature motif; other site 216591007844 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 7.9e-68 216591007845 8 probable transmembrane helices predicted for BCAL1549 by TMHMM2.0 at aa 36-58, 68-90, 95-117, 121-143, 148-165, 185-207, 239-261 and 293-315 216591007846 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007847 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 216591007848 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 216591007849 Walker A/P-loop; other site 216591007850 ATP binding site [chemical binding]; other site 216591007851 Q-loop/lid; other site 216591007852 ABC transporter signature motif; other site 216591007853 Walker B; other site 216591007854 D-loop; other site 216591007855 H-loop/switch region; other site 216591007856 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 216591007857 HMMPfam hit to PF00005, ABC transporter, score 1.6e-24 216591007858 PS00211 ABC transporters family signature. 216591007859 HMMPfam hit to PF00005, ABC transporter, score 5.9e-48 216591007860 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007861 Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412 216591007862 Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940 216591007863 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 216591007864 HMMPfam hit to PF00480, ROK family, score 3.7e-09 216591007865 Predicted helix-turn-helix motif with score 981.000, SD 2.53 at aa 33-54, sequence ASKADLARLANMTGTAVGSIIG 216591007866 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 216591007867 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591007868 substrate binding pocket [chemical binding]; other site 216591007869 membrane-bound complex binding site; other site 216591007870 HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 0.0028 216591007871 ribonuclease R; Region: RNase_R; TIGR02063 216591007872 Ribonuclease B OB domain; Region: OB_RNB; pfam08206 216591007873 RNB domain; Region: RNB; pfam00773 216591007874 S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471 216591007875 RNA binding site [nucleotide binding]; other site 216591007876 HMMPfam hit to PF08206, Ribonuclease B OB domain, score 1.3e-29 216591007877 HMMPfam hit to PF00773, RNB-like protein, score 9.1e-92 216591007878 PS01175 Ribonuclease II family signature. 216591007879 HMMPfam hit to PF00575, S1 RNA binding domain, score 4.3e-14 216591007880 RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032 216591007881 23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181 216591007882 SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588 216591007883 HMMPfam hit to PF08032, RNA 2'-O ribose methyltransferase subs, score 3e-17 216591007884 HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 1.6e-59 216591007885 N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023 216591007886 Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583 216591007887 amidase catalytic site [active] 216591007888 Zn binding residues [ion binding]; other site 216591007889 substrate binding site [chemical binding]; other site 216591007890 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 216591007891 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007892 HMMPfam hit to PF01510, N-acetylmuramoyl-L-alanine amidase, score 4.2e-37 216591007893 HMMPfam hit to PF01471, Putative peptidoglycan binding domain, score 0.0034 216591007894 RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398 216591007895 tetramer (dimer of dimers) interface [polypeptide binding]; other site 216591007896 active site 216591007897 dimer interface [polypeptide binding]; other site 216591007898 HMMPfam hit to PF06026, Ribose 5-phosphate isomerase A (phosph, score 2.6e-83 216591007899 PS00063 Aldo/keto reductase family putative active site signature. 216591007900 Transcriptional regulators [Transcription]; Region: FadR; COG2186 216591007901 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591007902 DNA-binding site [nucleotide binding]; DNA binding site 216591007903 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 216591007904 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 7.2e-08 216591007905 HMMPfam hit to PF07729, FCD domain, score 1.1e-26 216591007906 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Rossm, score 1.5e-31 216591007907 BcenGI7 216591007908 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007909 UMP phosphatase; Provisional; Region: PRK10444 216591007910 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007911 Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; cl01542 216591007912 Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299 216591007913 HMMPfam hit to PF04865, Baseplate J-like protein, score 1.6e-28 216591007914 Phage protein GP46; Region: GP46; pfam07409 216591007915 HMMPfam hit to PF07409, Phage protein GP46, score 3.6e-20 216591007916 Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; cl15410 216591007917 Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379 216591007918 Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796 216591007919 HMMPfam hit to PF06893, Bacteriophage Mu P protein, score 4.8e-62 216591007920 Mu-like prophage DNA circulation protein [General function prediction only]; Region: COG4228 216591007921 DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157 216591007922 HMMPfam hit to PF07157, DNA circulation protein N-terminus, score 3.1e-20 216591007923 Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145 216591007924 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786 216591007925 Mu-like prophage FluMu protein gp41 [Function unknown]; Region: COG4518 216591007926 PS00430 TonB-dependent receptor proteins signature 1. 216591007927 Phage tail sheath protein; Region: Phage_sheath_1; cl01389 216591007928 Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386 216591007929 HMMPfam hit to PF06274, Bacteriophage Mu tail sheath protein (GpL, score 7e-39 216591007930 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591007931 Domain of unknown function (DUF1834); Region: DUF1834; cl02087 216591007932 Phage virion morphogenesis family; Region: Phage_tail_S; cl02089 216591007933 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007934 Protein of unknown function (DUF1320); Region: DUF1320; cl01818 216591007935 Protein of unknown function (DUF1018); Region: DUF1018; cl01815 216591007936 1 probable transmembrane helix predicted for BCAL1583 by TMHMM2.0 at aa 7-29 216591007937 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 216591007938 IHF dimer interface [polypeptide binding]; other site 216591007939 IHF - DNA interface [nucleotide binding]; other site 216591007940 HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 4.5e-44 216591007941 PS00045 Bacterial histone-like DNA-binding proteins signature. 216591007942 Protein of unknown function (DUF3164); Region: DUF3164; pfam11363 216591007943 AAA domain; Region: AAA_22; pfam13401 216591007944 AAA domain; Region: AAA_30; pfam13604 216591007945 PS00017 ATP/GTP-binding site motif A (P-loop). 216591007946 Integrase core domain; Region: rve; pfam00665 216591007947 Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299 216591007948 HMMPfam hit to PF00665, Integrase core domain, score 1.1e-12 216591007949 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591007950 phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111 216591007951 Predicted helix-turn-helix motif with score 1088.000, SD 2.89 at aa 23-44, sequence KTIKEWAQEHGYDYVLVSRVIR 216591007952 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591007953 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591007954 non-specific DNA binding site [nucleotide binding]; other site 216591007955 salt bridge; other site 216591007956 sequence-specific DNA binding site [nucleotide binding]; other site 216591007957 HMMPfam hit to PF01381, Helix-turn-helix, score 4.7e-06 216591007958 Predicted helix-turn-helix motif with score 1321.000, SD 3.69 at aa 18-39, sequence LSQSAFADVAGVTKTTQGNYET 216591007959 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007960 Protein of unknown function (DUF4063); Region: DUF4063; pfam13272 216591007961 1 probable transmembrane helix predicted for BCAL1598 by TMHMM2.0 at aa 13-30 216591007962 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 216591007963 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591007964 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591007965 catalytic residue [active] 216591007966 1 probable transmembrane helix predicted for BCAL1599 by TMHMM2.0 at aa 20-42 216591007967 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 1.5e-09 216591007968 1 probable transmembrane helix predicted for BCAL1599a by TMHMM2.0 at aa 15-34 216591007969 Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755 216591007970 HMMPfam hit to PF01258, Prokaryotic dksA/traR C4-type zinc finge, score 4.9e-12 216591007971 citrate (Si)-synthase, eukaryotic; Region: cit_synth_euk; TIGR01793 216591007972 1 probable transmembrane helix predicted for BCAL1601 by TMHMM2.0 at aa 71-93 216591007973 Protein of unknown function (DUF1804); Region: DUF1804; pfam08822 216591007974 Homeodomain-like domain; Region: HTH_23; cl17451 216591007975 Predicted helix-turn-helix motif with score 1641.000, SD 4.78 at aa 19-40, sequence MPLTTAADVCKVSYQTARNWKR 216591007976 Phage-related terminase [General function prediction only]; Region: COG5362; cl02216 216591007977 Protein of unknown function (DUF935); Region: DUF935; pfam06074 216591007978 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591007979 Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072 216591007980 HMMPfam hit to PF04233, Phage Mu protein F like protein, score 1.6e-27 216591007981 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591007982 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591007983 dimer interface [polypeptide binding]; other site 216591007984 conserved gate region; other site 216591007985 putative PBP binding loops; other site 216591007986 ABC-ATPase subunit interface; other site 216591007987 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.7e-15 216591007988 1 probable transmembrane helix predicted for BCAL1609 by TMHMM2.0 at aa 15-37 216591007989 cystine transporter subunit; Provisional; Region: PRK11260 216591007990 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591007991 substrate binding pocket [chemical binding]; other site 216591007992 membrane-bound complex binding site; other site 216591007993 hinge residues; other site 216591007994 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 2.6e-96 216591007995 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591007996 dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286 216591007997 Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738 216591007998 quinone interaction residues [chemical binding]; other site 216591007999 active site 216591008000 catalytic residues [active] 216591008001 FMN binding site [chemical binding]; other site 216591008002 substrate binding site [chemical binding]; other site 216591008003 HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, score 6.7e-105 216591008004 PS00912 Dihydroorotate dehydrogenase signature 2. 216591008005 PS00911 Dihydroorotate dehydrogenase signature 1. 216591008006 arginyl-tRNA-protein transferase; Provisional; Region: PRK01305 216591008007 Arginine-tRNA-protein transferase, N terminus; Region: ATE_N; pfam04376 216591008008 Arginine-tRNA-protein transferase, C terminus; Region: ATE_C; pfam04377 216591008009 HMMPfam hit to PF04377, Arginine-tRNA-protein transferase, C terminu, score 1.4e-46 216591008010 Predicted helix-turn-helix motif with score 1290.000, SD 3.58 at aa 203-224, sequence LWQIEQAKSLGLPYVYLGYWIR 216591008011 HMMPfam hit to PF04376, Arginine-tRNA-protein transferase, N terminu, score 2.2e-26 216591008012 leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301 216591008013 HMMPfam hit to PF03588, Leucyl/phenylalanyl-tRNA protein transf, score 8.6e-83 216591008014 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_4; cd04511 216591008015 nudix motif; other site 216591008016 HMMPfam hit to PF00293, NUDIX domain, score 6.5e-17 216591008017 PS00893 mutT domain signature. 216591008018 hypothetical protein; Provisional; Region: PRK02487 216591008019 HMMPfam hit to PF03928, Domain of unknown function (DUF336), score 5e-39 216591008020 Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076 216591008021 HMMPfam hit to PF00893, Small Multidrug Resistance protein, score 6.3e-38 216591008022 4 probable transmembrane helices predicted for BCAL1616 by TMHMM2.0 at aa 5-22, 32-51, 58-80 and 84-106 216591008023 3-hydroxyisobutyryl-CoA hydrolase; Provisional; Region: PRK05617 216591008024 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591008025 substrate binding site [chemical binding]; other site 216591008026 oxyanion hole (OAH) forming residues; other site 216591008027 trimer interface [polypeptide binding]; other site 216591008028 2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766 216591008029 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 3.2e-17 216591008030 4 probable transmembrane helices predicted for BCAL1618 by TMHMM2.0 at aa 5-26, 46-68, 75-97 and 112-134 216591008031 alkanesulfonate monooxygenase; Provisional; Region: PRK00719 216591008032 Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094 216591008033 active site 216591008034 dimer interface [polypeptide binding]; other site 216591008035 non-prolyl cis peptide bond; other site 216591008036 insertion regions; other site 216591008037 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 0.0015 216591008038 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591008039 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591008040 dimer interface [polypeptide binding]; other site 216591008041 conserved gate region; other site 216591008042 putative PBP binding loops; other site 216591008043 ABC-ATPase subunit interface; other site 216591008044 7 probable transmembrane helices predicted for BCAL1620 by TMHMM2.0 at aa 15-37, 75-97, 107-129, 136-155, 175-197, 199-221 and 231-253 216591008045 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.7e-33 216591008046 aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247 216591008047 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 216591008048 Walker A/P-loop; other site 216591008049 ATP binding site [chemical binding]; other site 216591008050 Q-loop/lid; other site 216591008051 ABC transporter signature motif; other site 216591008052 Walker B; other site 216591008053 D-loop; other site 216591008054 H-loop/switch region; other site 216591008055 HMMPfam hit to PF00005, ABC transporter, score 3.8e-57 216591008056 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008057 PS00211 ABC transporters family signature. 216591008058 Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585 216591008059 HMMPfam hit to PF03459, TOBE domain, score 8.5e-14 216591008060 tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815 216591008061 Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801 216591008062 FMN binding site [chemical binding]; other site 216591008063 active site 216591008064 catalytic residues [active] 216591008065 substrate binding site [chemical binding]; other site 216591008066 HMMPfam hit to PF01207, Dihydrouridine synthase (Dus), score 1.1e-103 216591008067 PS01136 Uncharacterized protein family UPF0034 signature. 216591008068 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 216591008069 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591008070 Coenzyme A binding pocket [chemical binding]; other site 216591008071 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.2e-17 216591008072 Family of unknown function (DUF695); Region: DUF695; pfam05117 216591008073 Protein of unknown function (DUF1260); Region: DUF1260; pfam06877 216591008074 HMMPfam hit to PF06877, Protein of unknown function (DUF1260), score 2.1e-07 216591008075 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008076 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008077 Probable gene remnant. Similar to the C-terminal region of Burkholderia cenocepacia HI2424 hypothetical protein UniProt:Q4LRE5 (EMBL:AAHL01000024) (180 aa) fasta scores: E()=6.1e-24, 85.135% id in 74 aa 216591008078 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_8; cd07246 216591008079 putative dimer interface [polypeptide binding]; other site 216591008080 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591008081 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 5.2e-13 216591008082 FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203 216591008083 GAF domain; Region: GAF; pfam01590 216591008084 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591008085 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591008086 metal binding site [ion binding]; metal-binding site 216591008087 active site 216591008088 I-site; other site 216591008089 HMMPfam hit to PF00990, GGDEF domain, score 1.8e-42 216591008090 HMMPfam hit to PF01590, GAF domain, score 1.6e-23 216591008091 1 probable transmembrane helix predicted for BCAL1635a by TMHMM2.0 at aa 4-21 216591008092 Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170 216591008093 PLD-like domain; Region: PLDc_2; pfam13091 216591008094 putative active site [active] 216591008095 catalytic site [active] 216591008096 Predicted transcriptional regulators [Transcription]; Region: COG1733 216591008097 HxlR-like helix-turn-helix; Region: HxlR; pfam01638 216591008098 HMMPfam hit to PF01638, HxlR-like helix-turn-helix, score 7.8e-29 216591008099 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 216591008100 CoenzymeA binding site [chemical binding]; other site 216591008101 subunit interaction site [polypeptide binding]; other site 216591008102 PHB binding site; other site 216591008103 HMMPfam hit to PF03061, Thioesterase superfamily, score 9.6e-11 216591008104 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591008105 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 216591008106 active site 216591008107 catalytic tetrad [active] 216591008108 HMMPfam hit to PF00248, Aldo/keto reductase family, score 2.4e-54 216591008109 citrate-proton symporter; Provisional; Region: PRK15075 216591008110 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591008111 putative substrate translocation pore; other site 216591008112 HMMPfam hit to PF00083, Sugar (and other) transporter, score 1.3e-18 216591008113 12 probable transmembrane helices predicted for BCAL1640 by TMHMM2.0 at aa 23-45, 60-82, 94-116, 126-148, 161-183, 193-212, 243-262, 277-299, 306-328, 338-360, 372-394 and 404-421 216591008114 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.1e-22 216591008115 PS00216 Sugar transport proteins signature 1. 216591008116 hypothetical protein; Provisional; Region: PRK07079 216591008117 Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_2; cd05679 216591008118 metal binding site [ion binding]; metal-binding site 216591008119 putative dimer interface [polypeptide binding]; other site 216591008120 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 4.7e-21 216591008121 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 1.3e-08 216591008122 PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 216591008123 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591008124 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591008125 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591008126 dimerization interface [polypeptide binding]; other site 216591008127 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.9e-19 216591008128 Predicted helix-turn-helix motif with score 1565.000, SD 4.52 at aa 27-48, sequence GSISDASARLHVAVSAISRQIA 216591008129 PS00044 Bacterial regulatory proteins, lysR family signature. 216591008130 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.1e-38 216591008131 tRNA 2-selenouridine synthase; Provisional; Region: PRK11784 216591008132 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125 216591008133 active site residue [active] 216591008134 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591008135 Walker A/P-loop; other site 216591008136 ATP binding site [chemical binding]; other site 216591008137 Q-loop/lid; other site 216591008138 ABC transporter signature motif; other site 216591008139 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008140 Predicted permease; Region: DUF318; cl17795 216591008141 9 probable transmembrane helices predicted for BCAL1644 by TMHMM2.0 at aa 10-28, 80-102, 112-134, 146-168, 172-191, 232-254, 264-286, 291-313 and 328-350 216591008142 HMMPfam hit to PF03773, Predicted permease, score 4.8e-47 216591008143 PS01047 Heavy-metal-associated domain. 216591008144 ABC-2 type transporter; Region: ABC2_membrane; cl17235 216591008145 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 216591008146 6 probable transmembrane helices predicted for BCAL1646 by TMHMM2.0 at aa 45-67, 77-99, 128-150, 165-187, 192-214 and 249-271 216591008147 HMMPfam hit to PF01061, ABC-2 type transporter, score 1.4e-29 216591008148 nodulation ABC transporter NodI; Provisional; Region: PRK13537 216591008149 ATP-binding cassette domain of the lipid transporters, subfamily A; Region: ABC_subfamily_A; cd03263 216591008150 Walker A/P-loop; other site 216591008151 ATP binding site [chemical binding]; other site 216591008152 Q-loop/lid; other site 216591008153 ABC transporter signature motif; other site 216591008154 Walker B; other site 216591008155 D-loop; other site 216591008156 H-loop/switch region; other site 216591008157 HMMPfam hit to PF00005, ABC transporter, score 3.3e-66 216591008158 PS00211 ABC transporters family signature. 216591008159 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008160 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591008161 Ligand Binding Site [chemical binding]; other site 216591008162 HMMPfam hit to PF00582, Universal stress protein family, score 1e-10 216591008163 Protein of unknown function (DUF2939); Region: DUF2939; pfam11159 216591008164 2 probable transmembrane helices predicted for BCAL1649 by TMHMM2.0 at aa 15-37 and 85-107 216591008165 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591008166 LexA repressor; Validated; Region: PRK00215 216591008167 LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726 216591008168 Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529 216591008169 Catalytic site [active] 216591008170 HMMPfam hit to PF00717, Peptidase S24-like, score 2.2e-22 216591008171 HMMPfam hit to PF01726, LexA DNA binding domain, score 6.5e-35 216591008172 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591008173 Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531 216591008174 substrate binding pocket [chemical binding]; other site 216591008175 membrane-bound complex binding site; other site 216591008176 1 probable transmembrane helix predicted for BCAL1652 by TMHMM2.0 at aa 7-29 216591008177 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 2e-14 216591008178 PS00757 Prokaryotic sulfate-binding proteins signature 2. 216591008179 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 216591008180 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591008181 dimer interface [polypeptide binding]; other site 216591008182 conserved gate region; other site 216591008183 putative PBP binding loops; other site 216591008184 ABC-ATPase subunit interface; other site 216591008185 6 probable transmembrane helices predicted for BCAL1653 by TMHMM2.0 at aa 12-34, 66-88, 101-123, 138-160, 190-212 and 244-266 216591008186 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.9e-26 216591008187 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591008188 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 216591008189 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591008190 dimer interface [polypeptide binding]; other site 216591008191 conserved gate region; other site 216591008192 putative PBP binding loops; other site 216591008193 ABC-ATPase subunit interface; other site 216591008194 6 probable transmembrane helices predicted for BCAL1654 by TMHMM2.0 at aa 34-56, 82-104, 121-143, 153-175, 214-236 and 259-281 216591008195 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.8e-17 216591008196 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591008197 ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: CysA; COG1118 216591008198 ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296 216591008199 Walker A/P-loop; other site 216591008200 ATP binding site [chemical binding]; other site 216591008201 Q-loop/lid; other site 216591008202 ABC transporter signature motif; other site 216591008203 Walker B; other site 216591008204 D-loop; other site 216591008205 H-loop/switch region; other site 216591008206 TOBE-like domain; Region: TOBE_3; pfam12857 216591008207 HMMPfam hit to PF00005, ABC transporter, score 5.8e-71 216591008208 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008209 PS00211 ABC transporters family signature. 216591008210 HMMPfam hit to PF08402, TOBE domain, score 0.0023 216591008211 HMMPfam hit to PF03459, TOBE domain, score 0.0033 216591008212 transcriptional regulator CysB-like protein; Reviewed; Region: PRK12683 216591008213 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591008214 The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413 216591008215 substrate binding site [chemical binding]; other site 216591008216 dimerization interface [polypeptide binding]; other site 216591008217 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.4e-16 216591008218 Predicted helix-turn-helix motif with score 1606.000, SD 4.66 at aa 17-38, sequence MNLTEVANVLYTSQSGVSKQIK 216591008219 PS00044 Bacterial regulatory proteins, lysR family signature. 216591008220 HMMPfam hit to PF03466, LysR substrate binding domain, score 5.6e-48 216591008221 Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536 216591008222 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 216591008223 ligand binding site [chemical binding]; other site 216591008224 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 7.8e-09 216591008225 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 216591008226 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 216591008227 Walker A/P-loop; other site 216591008228 ATP binding site [chemical binding]; other site 216591008229 Q-loop/lid; other site 216591008230 ABC transporter signature motif; other site 216591008231 Walker B; other site 216591008232 D-loop; other site 216591008233 H-loop/switch region; other site 216591008234 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 216591008235 HMMPfam hit to PF00005, ABC transporter, score 9.9e-55 216591008236 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008237 HMMPfam hit to PF00005, ABC transporter, score 2e-17 216591008238 PS00211 ABC transporters family signature. 216591008239 Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454 216591008240 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591008241 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591008242 TM-ABC transporter signature motif; other site 216591008243 6 probable transmembrane helices predicted for BCAL1659 by TMHMM2.0 at aa 30-52, 77-99, 112-134, 180-202, 233-252 and 287-309 216591008244 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 2e-71 216591008245 PS00307 Legume lectins beta-chain signature. 216591008246 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591008247 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591008248 DNA binding site [nucleotide binding] 216591008249 domain linker motif; other site 216591008250 Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011 216591008251 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 5.1e-09 216591008252 Predicted helix-turn-helix motif with score 1745.000, SD 5.13 at aa 2-23, sequence ATIKDVAAMAGVSFTTVSHVVN 216591008253 PS00356 Bacterial regulatory proteins, lacI family signature. 216591008254 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 3.6e-23 216591008255 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 216591008256 Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174 216591008257 substrate binding site [chemical binding]; other site 216591008258 dimer interface [polypeptide binding]; other site 216591008259 ATP binding site [chemical binding]; other site 216591008260 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 9.6e-73 216591008261 PS00583 pfkB family of carbohydrate kinases signature 1. 216591008262 HMMPfam hit to PF08543, Phosphomethylpyrimidine kinase, score 8.4e-05 216591008263 PS00584 pfkB family of carbohydrate kinases signature 2. 216591008264 Tar ligand binding domain homologue; Region: TarH; pfam02203 216591008265 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591008266 dimerization interface [polypeptide binding]; other site 216591008267 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591008268 dimer interface [polypeptide binding]; other site 216591008269 Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015 216591008270 putative CheW interface [polypeptide binding]; other site 216591008271 1 probable transmembrane helix predicted for BCAL1662 by TMHMM2.0 at aa 13-35 216591008272 HMMPfam hit to PF00672, HAMP domain, score 5.3e-14 216591008273 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 4.6e-100 216591008274 PrkA family serine protein kinase; Provisional; Region: PRK15455 216591008275 AAA ATPase domain; Region: AAA_16; pfam13191 216591008276 Walker A motif; other site 216591008277 ATP binding site [chemical binding]; other site 216591008278 PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798 216591008279 HMMPfam hit to PF08298, PrkA AAA domain, score 3.8e-250 216591008280 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008281 HMMPfam hit to PF06798, PrkA serine protein kinase C-terminal domain, score 4.4e-172 216591008282 hypothetical protein; Provisional; Region: PRK05325 216591008283 HMMPfam hit to PF04285, Protein of unknown function (DUF444), score 5.3e-192 216591008284 SpoVR family protein; Provisional; Region: PRK11767 216591008285 Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719 216591008286 HMMPfam hit to PF04293, SpoVR like protein, score 5.1e-291 216591008287 alpha-ketoglutarate transporter; Provisional; Region: PRK10406 216591008288 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591008289 putative substrate translocation pore; other site 216591008290 HMMPfam hit to PF00083, Sugar (and other) transporter, score 2.4e-19 216591008291 12 probable transmembrane helices predicted for BCAL1666 by TMHMM2.0 at aa 20-39, 59-81, 93-115, 119-138, 158-180, 195-212, 242-264, 279-301, 308-325, 335-357, 370-392 and 402-419 216591008292 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.7e-19 216591008293 PS00217 Sugar transport proteins signature 2. 216591008294 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591008295 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591008296 substrate binding pocket [chemical binding]; other site 216591008297 membrane-bound complex binding site; other site 216591008298 hinge residues; other site 216591008299 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 9e-76 216591008300 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591008301 dimer interface [polypeptide binding]; other site 216591008302 conserved gate region; other site 216591008303 putative PBP binding loops; other site 216591008304 ABC-ATPase subunit interface; other site 216591008305 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.9e-12 216591008306 4 probable transmembrane helices predicted for BCAL1669 by TMHMM2.0 at aa 24-46, 71-93, 108-130 and 212-234 216591008307 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591008308 dimer interface [polypeptide binding]; other site 216591008309 conserved gate region; other site 216591008310 putative PBP binding loops; other site 216591008311 ABC-ATPase subunit interface; other site 216591008312 5 probable transmembrane helices predicted for BCAL1670 by TMHMM2.0 at aa 7-29, 39-61, 73-95, 105-127 and 201-223 216591008313 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6.2e-25 216591008314 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591008315 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 216591008316 Peptidase family M23; Region: Peptidase_M23; pfam01551 216591008317 HMMPfam hit to PF01551, Peptidase family M23, score 6.8e-52 216591008318 1 probable transmembrane helix predicted for BCAL1671 by TMHMM2.0 at aa 20-42 216591008319 CDS contains a frameshift after codon 42. Similar to Pseudomonas putida probable HTH-type transcriptional regulator ArpR UniProt:Q9KJC4 (EMBL:AF183959) (210 aa) fasta scores: E()=1.6e-15, 32.243% id in 214 aa, and to Burkholderia cenocepacia HI2424 regulatory protein, TetR UniProt:Q4LRA6 (EMBL:AAHL01000024) (215 aa) fasta scores: E()=7.5e-83, 99.065% id in 214 aa 216591008320 HMMPfam hit to PF08361, MAATS-type transcriptional repressor, C-term, score 1.2e-06 216591008321 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.7e-14 216591008322 Predicted helix-turn-helix motif with score 1373.000, SD 3.86 at aa 32-53, sequence TAMADLAEAAGMSRGAVYGHYR 216591008323 periplasmic multidrug efflux lipoprotein precursor; Reviewed; Region: PRK09578 216591008324 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 216591008325 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591008326 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008327 HMMPfam hit to PF00529, HlyD family secretion protein, score 6.1e-71 216591008328 multidrug efflux protein; Reviewed; Region: PRK09577 216591008329 Protein export membrane protein; Region: SecD_SecF; cl14618 216591008330 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 216591008331 11 probable transmembrane helices predicted for BCAL1675 by TMHMM2.0 at aa 10-32, 339-361, 365-387, 437-459, 474-496, 538-560, 864-886, 893-915, 920-942, 963-985 and 1000-1022 216591008332 Outer membrane efflux protein; Region: OEP; pfam02321 216591008333 Outer membrane efflux protein; Region: OEP; pfam02321 216591008334 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008335 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.9e-35 216591008336 HMMPfam hit to PF02321, Outer membrane efflux protein, score 6.5e-45 216591008337 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 216591008338 HMMPfam hit to PF00419, Fimbrial protein, score 1.9e-44 216591008339 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 216591008340 PapC N-terminal domain; Region: PapC_N; pfam13954 216591008341 Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577 216591008342 PapC C-terminal domain; Region: PapC_C; pfam13953 216591008343 HMMPfam hit to PF00577, Fimbrial Usher protein, score 7.6e-235 216591008344 PS01151 Fimbrial biogenesis outer membrane usher protein signature. 216591008345 putativi pili assembly chaperone; Provisional; Region: PRK11385 216591008346 Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345 216591008347 Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753 216591008348 1 probable transmembrane helix predicted for BCAL1679 by TMHMM2.0 at aa 13-32 216591008349 HMMPfam hit to PF00345, Gram-negative pili assembly chaperone, score 5.4e-47 216591008350 PS00635 Gram-negative pili assembly chaperone signature. 216591008351 HMMPfam hit to PF02753, Gram-negative pili assembly chaperone, score 7.3e-08 216591008352 Fimbrial protein; Region: Fimbrial; pfam00419 216591008353 1 probable transmembrane helix predicted for BCAL1680 by TMHMM2.0 at aa 13-32 216591008354 HMMPfam hit to PF00419, Fimbrial protein, score 0.014 216591008355 Predicted integral membrane proteins containing uncharacterized repeats [Function unknown]; Region: COG5563 216591008356 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008357 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591008358 S-adenosylmethionine binding site [chemical binding]; other site 216591008359 HMMPfam hit to PF08242, Methyltransferase domain, score 0.00013 216591008360 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 216591008361 SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335 216591008362 5 probable transmembrane helices predicted for BCAL1683 by TMHMM2.0 at aa 5-27, 34-56, 61-83, 120-139 and 149-171 216591008363 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008364 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591008365 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591008366 active site 216591008367 phosphorylation site [posttranslational modification] 216591008368 intermolecular recognition site; other site 216591008369 dimerization interface [polypeptide binding]; other site 216591008370 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591008371 DNA binding site [nucleotide binding] 216591008372 HMMPfam hit to PF00072, Response regulator receiver domain, score 3.9e-33 216591008373 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 2.6e-24 216591008374 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591008375 dimer interface [polypeptide binding]; other site 216591008376 phosphorylation site [posttranslational modification] 216591008377 Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581 216591008378 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591008379 ATP binding site [chemical binding]; other site 216591008380 Mg2+ binding site [ion binding]; other site 216591008381 G-X-G motif; other site 216591008382 2 probable transmembrane helices predicted for BCAL1685 by TMHMM2.0 at aa 10-32 and 157-179 216591008383 HMMPfam hit to PF00672, HAMP domain, score 4e-08 216591008384 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.1e-12 216591008385 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.7e-30 216591008386 1 probable transmembrane helix predicted for BCAL1687 by TMHMM2.0 at aa 5-27 216591008387 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008388 extracytoplasmic-function sigma-70 factor; Validated; Region: PRK07037 216591008389 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591008390 Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281 216591008391 HMMPfam hit to PF04542, Sigma-70 region, score 9.6e-12 216591008392 HMMPfam hit to PF08281, Sigma-70, region, score 1.7e-06 216591008393 HMMPfam hit to PF04545, Sigma-70, region, score 0.0025 216591008394 Predicted helix-turn-helix motif with score 1137.000, SD 3.06 at aa 171-192, sequence ETLQTAARALNVSQTLVHFMVR 216591008395 MbtH-like protein; Region: MbtH; cl01279 216591008396 HMMPfam hit to PF03621, MbtH-like protein, score 1.6e-29 216591008397 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 216591008398 HMMPfam hit to PF02668, Taurine catabolism dioxygenase TauD, TfdA fa, score 7.1e-09 216591008399 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 216591008400 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 216591008401 Walker A/P-loop; other site 216591008402 ATP binding site [chemical binding]; other site 216591008403 Q-loop/lid; other site 216591008404 ABC transporter signature motif; other site 216591008405 Walker B; other site 216591008406 D-loop; other site 216591008407 H-loop/switch region; other site 216591008408 HMMPfam hit to PF00005, ABC transporter, score 5.4e-57 216591008409 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008410 PS00211 ABC transporters family signature. 216591008411 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 216591008412 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 216591008413 ABC-ATPase subunit interface; other site 216591008414 dimer interface [polypeptide binding]; other site 216591008415 putative PBP binding regions; other site 216591008416 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 216591008417 ABC-ATPase subunit interface; other site 216591008418 dimer interface [polypeptide binding]; other site 216591008419 putative PBP binding regions; other site 216591008420 14 probable transmembrane helices predicted for BCAL1692 by TMHMM2.0 at aa 20-42, 68-90, 103-125, 129-150, 157-179, 249-271, 284-304, 314-336, 423-445, 477-499, 506-528, 597-619, 639-661 and 666-688 216591008421 HMMPfam hit to PF01032, FecCD transport family, score 1.7e-34 216591008422 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008423 HMMPfam hit to PF01032, FecCD transport family, score 2.9e-69 216591008424 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008425 siderophore-iron reductase FhuF; Region: Fe_III_red_FhuF; TIGR03951 216591008426 Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276 216591008427 FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575 216591008428 HMMPfam hit to PF06276, Ferric iron reductase protein FhuF, score 2.1e-12 216591008429 Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146 216591008430 Periplasmic binding protein; Region: Peripla_BP_2; pfam01497 216591008431 siderophore binding site; other site 216591008432 HMMPfam hit to PF01497, Periplasmic binding protein, score 1.3e-16 216591008433 cyclic peptide transporter; Region: cyc_pep_trnsptr; TIGR01194 216591008434 ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228 216591008435 Walker A/P-loop; other site 216591008436 ATP binding site [chemical binding]; other site 216591008437 Q-loop/lid; other site 216591008438 ABC transporter signature motif; other site 216591008439 Walker B; other site 216591008440 D-loop; other site 216591008441 H-loop/switch region; other site 216591008442 HMMPfam hit to PF00005, ABC transporter, score 4.3e-45 216591008443 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008444 6 probable transmembrane helices predicted for BCAL1695 by TMHMM2.0 at aa 34-56, 71-93, 139-158, 163-185, 253-275 and 285-307 216591008445 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008446 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 216591008447 acyl-activating enzyme (AAE) consensus motif; other site 216591008448 AMP binding site [chemical binding]; other site 216591008449 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 216591008450 Condensation domain; Region: Condensation; pfam00668 216591008451 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 216591008452 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 216591008453 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591008454 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 216591008455 acyl-activating enzyme (AAE) consensus motif; other site 216591008456 AMP binding site [chemical binding]; other site 216591008457 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 216591008458 Condensation domain; Region: Condensation; pfam00668 216591008459 non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261 216591008460 Condensation domain; Region: Condensation; pfam00668 216591008461 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 216591008462 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 216591008463 acyl-activating enzyme (AAE) consensus motif; other site 216591008464 AMP binding site [chemical binding]; other site 216591008465 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 216591008466 HMMPfam hit to PF00501, AMP-binding enzyme, score 4.2e-125 216591008467 PS00455 Putative AMP-binding domain signature. 216591008468 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.3e-07 216591008469 HMMPfam hit to PF00668, Condensation domain, score 3.3e-80 216591008470 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.5e-129 216591008471 PS00455 Putative AMP-binding domain signature. 216591008472 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.5e-18 216591008473 PS00012 Phosphopantetheine attachment site. 216591008474 HMMPfam hit to PF00668, Condensation domain, score 6.5e-43 216591008475 HMMPfam hit to PF00668, Condensation domain, score 1.5e-59 216591008476 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.4e-169 216591008477 PS00455 Putative AMP-binding domain signature. 216591008478 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.1e-13 216591008479 Condensation domain; Region: Condensation; pfam00668 216591008480 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 216591008481 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 216591008482 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 216591008483 acyl-activating enzyme (AAE) consensus motif; other site 216591008484 AMP binding site [chemical binding]; other site 216591008485 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 216591008486 Condensation domain; Region: Condensation; pfam00668 216591008487 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 216591008488 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 216591008489 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 216591008490 HMMPfam hit to PF00668, Condensation domain, score 1.4e-78 216591008491 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591008492 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.8e-128 216591008493 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 8.1e-16 216591008494 PS00012 Phosphopantetheine attachment site. 216591008495 HMMPfam hit to PF00668, Condensation domain, score 5.7e-43 216591008496 Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523 216591008497 Siderophore biosynthesis protein domain; Region: AlcB; smart01006 216591008498 L-lysine 6-monooxygenase (NADPH-requiring); Region: K_oxygenase; pfam13434 216591008499 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591008500 ferrichrome outer membrane transporter; Provisional; Region: PRK10044 216591008501 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591008502 N-terminal plug; other site 216591008503 ligand-binding site [chemical binding]; other site 216591008504 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.4e-21 216591008505 HMMPfam hit to PF00593, TonB dependent receptor, score 8.2e-24 216591008506 Formyltransferase, catalytic core domain; Region: FMT_core; cl00395 216591008507 catalytic site [active] 216591008508 Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523 216591008509 Siderophore biosynthesis protein domain; Region: AlcB; smart01006 216591008510 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 216591008511 M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666 216591008512 metal binding site [ion binding]; metal-binding site 216591008513 putative dimer interface [polypeptide binding]; other site 216591008514 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 2.2e-73 216591008515 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 1.9e-09 216591008516 cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077 216591008517 Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130 216591008518 catalytic triad [active] 216591008519 HMMPfam hit to PF07685, CobB/CobQ-like glutamine amidotransferase do, score 6.7e-36 216591008520 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 2.8e-24 216591008521 ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109 216591008522 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561 216591008523 homodimer interface [polypeptide binding]; other site 216591008524 Walker A motif; other site 216591008525 ATP binding site [chemical binding]; other site 216591008526 hydroxycobalamin binding site [chemical binding]; other site 216591008527 Walker B motif; other site 216591008528 HMMPfam hit to PF02572, ATP:corrinoid adenosyltransferase BtuR, score 1.1e-89 216591008529 cobalamin biosynthesis protein CbiG; Provisional; Region: PRK07027 216591008530 Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642 216591008531 active site 216591008532 SAM binding site [chemical binding]; other site 216591008533 homodimer interface [polypeptide binding]; other site 216591008534 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 3.2e-76 216591008535 PS00839 Uroporphyrin-III C-methyltransferase signature 1. 216591008536 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 216591008537 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591008538 N-terminal plug; other site 216591008539 ligand-binding site [chemical binding]; other site 216591008540 HMMPfam hit to PF00593, TonB dependent receptor, score 2.5e-32 216591008541 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.1e-22 216591008542 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008543 cobalamin biosynthesis protein CobW; Region: CobW; TIGR02475 216591008544 CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492 216591008545 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683 216591008546 HMMPfam hit to PF02492, CobW/HypB/UreG, nucleotide-binding domain, score 2e-85 216591008547 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008548 HMMPfam hit to PF07683, Cobalamin synthesis protein cobW C-terminal, score 2.6e-25 216591008549 cobaltochelatase subunit CobN; Reviewed; Region: cobN; PRK05989 216591008550 CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150 216591008551 CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150 216591008552 HMMPfam hit to PF02514, CobN/Magnesium Chelatase, score 0 216591008553 Mg-protoporyphyrin IX chelatase; Region: chlI; CHL00081 216591008554 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591008555 Walker A motif; other site 216591008556 ATP binding site [chemical binding]; other site 216591008557 Walker B motif; other site 216591008558 arginine finger; other site 216591008559 HMMPfam hit to PF01078, Magnesium chelatase, subunit ChlI, score 2.5e-06 216591008560 HMMPfam hit to PF07728, ATPase family associated with various ce, score 2.1e-05 216591008561 Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057 216591008562 metal ion-dependent adhesion site (MIDAS); other site 216591008563 Uncharacterized BCR, YaiI/YqxD family COG1671; Region: DUF188; pfam02639 216591008564 HMMPfam hit to PF02639, Uncharacterized BCR, YaiI/YqxD family COG167, score 1.4e-57 216591008565 Domain of unknown function (DUF1993); Region: DUF1993; pfam09351 216591008566 Predicted protein tyrosine phosphatase [General function prediction only]; Region: COG4551 216591008567 active site 216591008568 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_10; cd04667 216591008569 nudix motif; other site 216591008570 HMMPfam hit to PF00293, NUDIX domain, score 9.4e-21 216591008571 PS00893 mutT domain signature. 216591008572 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591008573 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591008574 HMMPfam hit to PF02515, CoA-transferase family III, score 1.1e-52 216591008575 H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851 216591008576 Citrate transporter; Region: CitMHS; pfam03600 216591008577 11 probable transmembrane helices predicted for BCAL1719 by TMHMM2.0 at aa 35-54, 59-78, 91-113, 138-160, 173-192, 207-229, 267-286, 290-307, 320-342, 409-431 and 444-466 216591008578 HMMPfam hit to PF03600, Citrate transporter, score 4.6e-87 216591008579 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591008580 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591008581 active site 216591008582 HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal doma, score 9e-08 216591008583 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 1e-21 216591008584 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 3.7e-42 216591008585 Predicted helix-turn-helix motif with score 1057.000, SD 2.79 at aa 246-267, sequence ERILIAAEAIGLGQAALRRATQ 216591008586 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 3.2e-13 216591008587 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591008588 IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339 216591008589 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591008590 HMMPfam hit to PF02082, Transcriptional regulator, score 0.0015 216591008591 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 2.1e-09 216591008592 PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in...; Region: GH18_PF-ChiA-like; cd06543 216591008593 active site 216591008594 Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215 216591008595 aromatic chitin/cellulose binding site residues [chemical binding]; other site 216591008596 Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215 216591008597 aromatic chitin/cellulose binding site residues [chemical binding]; other site 216591008598 HMMPfam hit to PF02839, Carbohydrate binding domain, score 1e-14 216591008599 HMMPfam hit to PF02839, Carbohydrate binding domain, score 4.9e-16 216591008600 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008601 1 probable transmembrane helix predicted for BCAL1722 by TMHMM2.0 at aa 13-35 216591008602 Cobalamin biosynthesis protein CbiG [Coenzyme metabolism]; Region: CbiG; COG2073 216591008603 Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760 216591008604 Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761 216591008605 Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646 216591008606 active site 216591008607 SAM binding site [chemical binding]; other site 216591008608 homodimer interface [polypeptide binding]; other site 216591008609 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 2.5e-42 216591008610 HMMPfam hit to PF01890, CbiG, score 0.004 216591008611 Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645 216591008612 active site 216591008613 SAM binding site [chemical binding]; other site 216591008614 homodimer interface [polypeptide binding]; other site 216591008615 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 1e-32 216591008616 precorrin-8X methylmutase; Reviewed; Region: cobH; PRK08285 216591008617 Precorrin-8X methylmutase; Region: CbiC; pfam02570 216591008618 HMMPfam hit to PF02570, Precorrin-8X methylmutase, score 1e-66 216591008619 precorrin-3B synthase; Region: CobG; TIGR02435 216591008620 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 216591008621 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 216591008622 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008623 HMMPfam hit to PF03460, Nitrite/Sulfite reductase ferredoxin-lik, score 1e-07 216591008624 HMMPfam hit to PF01077, Nitrite and sulphite reductase 4Fe-4S do, score 1.4e-10 216591008625 HMMPfam hit to PF03460, Nitrite/Sulfite reductase ferredoxin-lik, score 2.1e-10 216591008626 Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644 216591008627 active site 216591008628 putative homodimer interface [polypeptide binding]; other site 216591008629 SAM binding site [chemical binding]; other site 216591008630 Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242 216591008631 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Region: CbiT; TIGR02469 216591008632 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 3.9e-14 216591008633 PS00211 ABC transporters family signature. 216591008634 cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075 216591008635 HMMPfam hit to PF01888, CbiD, score 9.4e-84 216591008636 cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057 216591008637 HMMPfam hit to PF02571, Precorrin-6x reductase CbiJ/CobK, score 1.4e-20 216591008638 Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641 216591008639 active site 216591008640 SAM binding site [chemical binding]; other site 216591008641 homodimer interface [polypeptide binding]; other site 216591008642 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 2.1e-58 216591008643 PS00839 Uroporphyrin-III C-methyltransferase signature 1. 216591008644 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008645 Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807 216591008646 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591008647 putative substrate translocation pore; other site 216591008648 12 probable transmembrane helices predicted for BCAL1731 by TMHMM2.0 at aa 7-26, 41-63, 70-89, 99-121, 133-155, 159-181, 210-232, 242-264, 273-292, 297-319, 331-353 and 363-382 216591008649 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.4e-22 216591008650 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008651 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008652 MarR family; Region: MarR_2; cl17246 216591008653 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591008654 HMMPfam hit to PF01047, MarR family, score 1e-14 216591008655 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591008656 GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048 216591008657 C-terminal domain interface [polypeptide binding]; other site 216591008658 GSH binding site (G-site) [chemical binding]; other site 216591008659 dimer interface [polypeptide binding]; other site 216591008660 C-terminal, alpha helical domain of Ure2p and related Glutathione S-transferase-like proteins; Region: GST_C_Ure2p_like; cd03178 216591008661 dimer interface [polypeptide binding]; other site 216591008662 N-terminal domain interface [polypeptide binding]; other site 216591008663 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 2.5e-08 216591008664 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 8.1e-13 216591008665 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591008666 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591008667 trimer interface [polypeptide binding]; other site 216591008668 eyelet of channel; other site 216591008669 HMMPfam hit to PF00267, Gram-negative porin, score 0.00066 216591008670 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591008671 AAA domain; Region: AAA_22; pfam13401 216591008672 AAA ATPase domain; Region: AAA_16; pfam13191 216591008673 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591008674 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591008675 DNA binding residues [nucleotide binding] 216591008676 dimerization interface [polypeptide binding]; other site 216591008677 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 2.1e-17 216591008678 Predicted helix-turn-helix motif with score 1382.000, SD 3.89 at aa 848-869, sequence LSNKEIAVALAVGEETVKWHLK 216591008679 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008680 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591008681 quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754 216591008682 Quinone oxidoreductase (QOR); Region: QOR2; cd05286 216591008683 NADP binding site [chemical binding]; other site 216591008684 dimer interface [polypeptide binding]; other site 216591008685 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 9.2e-18 216591008686 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.4e-43 216591008687 PS01162 Quinone oxidoreductase / zeta-crystallin signature. 216591008688 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 216591008689 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 216591008690 HMMPfam hit to PF02668, Taurine catabolism dioxygenase TauD, TfdA fa, score 9.3e-76 216591008691 Prokaryotic protein of unknown function (DUF849); Region: DUF849; pfam05853 216591008692 HMMPfam hit to PF05853, Prokaryotic protein of unknown function (DUF, score 3.4e-13 216591008693 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591008694 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591008695 putative substrate translocation pore; other site 216591008696 12 probable transmembrane helices predicted for BCAL1740 by TMHMM2.0 at aa 20-42, 62-84, 91-113, 123-145, 152-174, 179-201, 240-262, 277-299, 311-333, 337-359, 372-394 and 404-426 216591008697 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.1e-39 216591008698 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008699 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008700 Serine hydrolase; Region: Ser_hydrolase; pfam06821 216591008701 HMMPfam hit to PF06821, Alpha/Beta hydrolase family of unknown funct, score 2.5e-48 216591008702 ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134 216591008703 hypothetical protein; Provisional; Region: PRK11622 216591008704 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 0.013 216591008705 1 probable transmembrane helix predicted for BCAL1742 by TMHMM2.0 at aa 13-35 216591008706 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 216591008707 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591008708 Walker A/P-loop; other site 216591008709 ATP binding site [chemical binding]; other site 216591008710 Q-loop/lid; other site 216591008711 ABC transporter signature motif; other site 216591008712 Walker B; other site 216591008713 D-loop; other site 216591008714 H-loop/switch region; other site 216591008715 TOBE domain; Region: TOBE_2; pfam08402 216591008716 HMMPfam hit to PF00005, ABC transporter, score 7.9e-59 216591008717 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008718 PS00211 ABC transporters family signature. 216591008719 HMMPfam hit to PF08402, TOBE domain, score 0.0045 216591008720 HMMPfam hit to PF03459, TOBE domain, score 0.00033 216591008721 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 216591008722 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591008723 dimer interface [polypeptide binding]; other site 216591008724 conserved gate region; other site 216591008725 putative PBP binding loops; other site 216591008726 ABC-ATPase subunit interface; other site 216591008727 6 probable transmembrane helices predicted for BCAL1744 by TMHMM2.0 at aa 13-35, 69-91, 103-125, 153-175, 202-224 and 257-279 216591008728 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 9e-12 216591008729 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591008730 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008731 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 216591008732 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591008733 dimer interface [polypeptide binding]; other site 216591008734 conserved gate region; other site 216591008735 putative PBP binding loops; other site 216591008736 ABC-ATPase subunit interface; other site 216591008737 7 probable transmembrane helices predicted for BCAL1745 by TMHMM2.0 at aa 12-34, 71-93, 105-127, 137-159, 180-202, 212-231 and 244-263 216591008738 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.7e-17 216591008739 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008740 1 probable transmembrane helix predicted for BCAL1747A by TMHMM2.0 at aa 12-29 216591008741 Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162 216591008742 glycerate dehydrogenase; Provisional; Region: PRK06487 216591008743 putative ligand binding site [chemical binding]; other site 216591008744 putative NAD binding site [chemical binding]; other site 216591008745 catalytic site [active] 216591008746 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 3.6e-22 216591008747 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 3.3e-72 216591008748 PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 216591008749 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591008750 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591008751 HMMPfam hit to PF02515, CoA-transferase family III, score 1.9e-73 216591008752 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938 216591008753 active site 216591008754 catalytic residues [active] 216591008755 metal binding site [ion binding]; metal-binding site 216591008756 HMMPfam hit to PF00682, HMGL-like, score 6.3e-55 216591008757 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008758 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253 216591008759 dimer interface [polypeptide binding]; other site 216591008760 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591008761 metal binding site [ion binding]; metal-binding site 216591008762 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 4e-06 216591008763 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 216591008764 PS00120 Lipases, serine active site. 216591008765 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591008766 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591008767 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421 216591008768 putative dimerization interface [polypeptide binding]; other site 216591008769 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.1e-17 216591008770 Predicted helix-turn-helix motif with score 1146.000, SD 3.09 at aa 43-64, sequence GSLTKAAEHGQLTLSAVSKRIA 216591008771 PS00044 Bacterial regulatory proteins, lysR family signature. 216591008772 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.9e-33 216591008773 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591008774 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591008775 benzoate transport; Region: 2A0115; TIGR00895 216591008776 putative substrate translocation pore; other site 216591008777 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591008778 putative substrate translocation pore; other site 216591008779 HMMPfam hit to PF00083, Sugar (and other) transporter, score 4.7e-08 216591008780 12 probable transmembrane helices predicted for BCAL1754 by TMHMM2.0 at aa 12-34, 54-73, 82-100, 110-132, 139-161, 166-188, 257-279, 294-316, 321-340, 344-363, 384-403 and 407-429 216591008781 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 8.7e-32 216591008782 PS00217 Sugar transport proteins signature 2. 216591008783 PS00216 Sugar transport proteins signature 1. 216591008784 RNA ligase; Region: RNA_ligase; pfam09414 216591008785 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 216591008786 Zn2+ binding site [ion binding]; other site 216591008787 Mg2+ binding site [ion binding]; other site 216591008788 AAA domain; Region: AAA_33; pfam13671 216591008789 HMMPfam hit to PF01966, HD domain, score 2.8e-05 216591008790 1 probable transmembrane helix predicted for BCAL1758 by TMHMM2.0 at aa 177-199 216591008791 Nitronate monooxygenase; Region: NMO; pfam03060 216591008792 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 216591008793 FMN binding site [chemical binding]; other site 216591008794 substrate binding site [chemical binding]; other site 216591008795 putative catalytic residue [active] 216591008796 HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 2.3e-79 216591008797 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008798 Uncharacterized conserved protein [Function unknown]; Region: COG3791 216591008799 HMMPfam hit to PF04828, Protein of unknown function (DUF636), score 1.2e-17 216591008800 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591008801 MarR family; Region: MarR; pfam01047 216591008802 HMMPfam hit to PF01047, MarR family, score 1.4e-21 216591008803 Predicted acetyltransferase [General function prediction only]; Region: COG3393 216591008804 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591008805 Coenzyme A binding pocket [chemical binding]; other site 216591008806 HMMPfam hit to PF08445, FR47-like protein, score 7.9e-16 216591008807 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 8.5e-13 216591008808 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591008809 1 probable transmembrane helix predicted for BCAL1763 by TMHMM2.0 at aa 5-24 216591008810 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591008811 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591008812 peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561 216591008813 HMMPfam hit to PF02566, OsmC-like protein, score 4.9e-36 216591008814 alpha-ketoglutarate transporter; Provisional; Region: PRK10406 216591008815 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591008816 putative substrate translocation pore; other site 216591008817 HMMPfam hit to PF00083, Sugar (and other) transporter, score 1.7e-21 216591008818 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.9e-18 216591008819 11 probable transmembrane helices predicted for BCAL1767 by TMHMM2.0 at aa 66-88, 95-114, 119-141, 162-184, 199-216, 248-270, 285-307, 314-336, 341-363, 376-398 and 408-427 216591008820 PS00217 Sugar transport proteins signature 2. 216591008821 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008822 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591008823 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591008824 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591008825 dimerization interface [polypeptide binding]; other site 216591008826 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-33 216591008827 PS00215 Mitochondrial energy transfer proteins signature. 216591008828 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.2e-17 216591008829 PS00044 Bacterial regulatory proteins, lysR family signature. 216591008830 Predicted helix-turn-helix motif with score 1347.000, SD 3.77 at aa 19-40, sequence ANFSTAAQRLHLSVSSLSKRIN 216591008831 Isopentenyl diphosphate isomerase (BS_ypgA, MTH48 and related proteins) [Coenzyme transport and metabolism]; Region: idi; COG1304 216591008832 TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186 216591008833 phosphate binding site [ion binding]; other site 216591008834 HMMPfam hit to PF01070, FMN-dependent dehydrogenase, score 1.1e-112 216591008835 PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 216591008836 Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412 216591008837 Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319 216591008838 HMMPfam hit to PF01738, Dienelactone hydrolase family, score 1.7e-58 216591008839 short chain dehydrogenase; Provisional; Region: PRK08265 216591008840 classical (c) SDRs; Region: SDR_c; cd05233 216591008841 NAD(P) binding site [chemical binding]; other site 216591008842 active site 216591008843 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.2e-22 216591008844 PS00061 Short-chain dehydrogenases/reductases family signature. 216591008845 Isochorismatase family; Region: Isochorismatase; pfam00857 216591008846 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431 216591008847 catalytic triad [active] 216591008848 conserved cis-peptide bond; other site 216591008849 HMMPfam hit to PF00857, Isochorismatase family, score 9.4e-11 216591008850 Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667 216591008851 inter-subunit interface; other site 216591008852 HMMPfam hit to PF00866, Ring hydroxylating beta subunit, score 1.7e-29 216591008853 anthranilate 1,2-dioxygenase, large subunit; Region: anthran_1_2_A; TIGR03228 216591008854 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938 216591008855 iron-sulfur cluster [ion binding]; other site 216591008856 [2Fe-2S] cluster binding site [ion binding]; other site 216591008857 C-terminal catalytic domain of the oxygenase alpha subunit of Pseudomonas resinovorans strain CA10 anthranilate 1,2-dioxygenase and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_AntDO-like; cd08879 216591008858 putative alpha subunit interface [polypeptide binding]; other site 216591008859 putative active site [active] 216591008860 putative substrate binding site [chemical binding]; other site 216591008861 Fe binding site [ion binding]; other site 216591008862 HMMPfam hit to PF00848, Ring hydroxylating alpha subunit (cat, score 4e-07 216591008863 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 5.2e-23 216591008864 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018 216591008865 Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185 216591008866 FMN-binding pocket [chemical binding]; other site 216591008867 flavin binding motif; other site 216591008868 phosphate binding motif [ion binding]; other site 216591008869 beta-alpha-beta structure motif; other site 216591008870 NAD binding pocket [chemical binding]; other site 216591008871 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591008872 catalytic loop [active] 216591008873 iron binding site [ion binding]; other site 216591008874 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 3.7e-16 216591008875 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591008876 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 8.8e-12 216591008877 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 3.5e-06 216591008878 HMMPfam hit to PF08021, Siderophore-interacting FAD-binding dom, score 0.00081 216591008879 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591008880 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591008881 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00086 216591008882 PS00041 Bacterial regulatory proteins, araC family signature. 216591008883 Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629 216591008884 Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244 216591008885 Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244 216591008886 HMMPfam hit to PF00593, TonB dependent receptor, score 7.9e-25 216591008887 PS01156 TonB-dependent receptor proteins signature 2. 216591008888 PS00116 DNA polymerase family B signature. 216591008889 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.7e-11 216591008890 1 probable transmembrane helix predicted for BCAL1777a by TMHMM2.0 at aa 21-43 216591008891 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915 216591008892 Protein export membrane protein; Region: SecD_SecF; cl14618 216591008893 PS00044 Bacterial regulatory proteins, lysR family signature. 216591008894 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 216591008895 11 probable transmembrane helices predicted for BCAL1778 by TMHMM2.0 at aa 10-32, 340-359, 369-391, 437-459, 469-491, 544-566, 873-892, 897-919, 929-946, 974-996 and 1006-1028 216591008896 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008897 ABC-type uncharacterized transport system, duplicated ATPase component [General function prediction only]; Region: COG4172 216591008898 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591008899 Walker A/P-loop; other site 216591008900 ATP binding site [chemical binding]; other site 216591008901 Q-loop/lid; other site 216591008902 ABC transporter signature motif; other site 216591008903 Walker B; other site 216591008904 D-loop; other site 216591008905 H-loop/switch region; other site 216591008906 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 216591008907 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591008908 Walker A/P-loop; other site 216591008909 ATP binding site [chemical binding]; other site 216591008910 Q-loop/lid; other site 216591008911 ABC transporter signature motif; other site 216591008912 Walker B; other site 216591008913 D-loop; other site 216591008914 H-loop/switch region; other site 216591008915 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 216591008916 HMMPfam hit to PF00005, ABC transporter, score 3.5e-61 216591008917 PS00211 ABC transporters family signature. 216591008918 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008919 HMMPfam hit to PF00005, ABC transporter, score 1.1e-54 216591008920 PS00211 ABC transporters family signature. 216591008921 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008922 N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911 216591008923 ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239 216591008924 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591008925 dimer interface [polypeptide binding]; other site 216591008926 conserved gate region; other site 216591008927 putative PBP binding loops; other site 216591008928 ABC-ATPase subunit interface; other site 216591008929 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.4e-47 216591008930 4 probable transmembrane helices predicted for BCAL1780 by TMHMM2.0 at aa 38-60, 165-187, 208-230 and 325-347 216591008931 ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174 216591008932 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591008933 dimer interface [polypeptide binding]; other site 216591008934 conserved gate region; other site 216591008935 putative PBP binding loops; other site 216591008936 ABC-ATPase subunit interface; other site 216591008937 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 8.5e-47 216591008938 6 probable transmembrane helices predicted for BCAL1781 by TMHMM2.0 at aa 9-31, 122-144, 156-178, 208-230, 267-289 and 317-339 216591008939 ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166 216591008940 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497 216591008941 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 1.2e-55 216591008942 CDS contains a nonsense mutation (amber) after codon 799. Similar to Xanthomonas axonopodis pv. citri TonB-dependent receptor BtuB UniProt:Q8PGK3 (EMBL:AE012011) (890 aa) fasta scores: E()=2.5e-101, 37.627% id in 885 aa, and to Burkholderia cenocepacia HI2424 TonB-dependent receptor UniProt:Q4LK07 (EMBL:AAHL01000064) (941 aa) fasta scores: E()=0, 99.150% id in 941 aa 216591008943 HMMPfam hit to PF00593, TonB dependent receptor, score 1.5e-25 216591008944 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.4e-15 216591008945 DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943 216591008946 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591008947 non-specific DNA binding site [nucleotide binding]; other site 216591008948 salt bridge; other site 216591008949 sequence-specific DNA binding site [nucleotide binding]; other site 216591008950 Cupin domain; Region: Cupin_2; pfam07883 216591008951 HMMPfam hit to PF07883, Cupin domain, score 1.4e-19 216591008952 HMMPfam hit to PF01381, Helix-turn-helix, score 2e-15 216591008953 Predicted helix-turn-helix motif with score 1423.000, SD 4.03 at aa 77-98, sequence LTLDETAGIAGISKPFLSQVER 216591008954 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591008955 Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848 216591008956 Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472 216591008957 HMMPfam hit to PF02472, Biopolymer transport protein ExbD/TolR, score 1.2e-05 216591008958 1 probable transmembrane helix predicted for BCAL1787 by TMHMM2.0 at aa 20-42 216591008959 Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472 216591008960 Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848 216591008961 HMMPfam hit to PF02472, Biopolymer transport protein ExbD/TolR, score 6.8e-13 216591008962 1 probable transmembrane helix predicted for BCAL1788 by TMHMM2.0 at aa 20-42 216591008963 Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811 216591008964 HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 3.1e-41 216591008965 3 probable transmembrane helices predicted for BCAL1789 by TMHMM2.0 at aa 71-93, 178-200 and 225-247 216591008966 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591008967 Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810 216591008968 Gram-negative bacterial tonB protein; Region: TonB; pfam03544 216591008969 HMMPfam hit to PF03544, Gram-negative bacterial tonB protein, score 6.3e-06 216591008970 1 probable transmembrane helix predicted for BCAL1790 by TMHMM2.0 at aa 36-58 216591008971 YbaK-like. The YbaK family of deacylase domains includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cd04332 216591008972 putative deacylase active site [active] 216591008973 HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associated do, score 7.9e-05 216591008974 YciI-like protein; Reviewed; Region: PRK12866 216591008975 HMMPfam hit to PF03795, YCII-related domain, score 5.6e-11 216591008976 Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598 216591008977 Mycobacterium tuberculosis CorA-like subfamily; Region: MtCorA-like; cd12830 216591008978 oligomer interface [polypeptide binding]; other site 216591008979 metal binding site [ion binding]; metal-binding site 216591008980 metal binding site [ion binding]; metal-binding site 216591008981 putative Cl binding site [ion binding]; other site 216591008982 basic sphincter; other site 216591008983 hydrophobic gate; other site 216591008984 periplasmic entrance; other site 216591008985 HMMPfam hit to PF01544, CorA-like Mg2+ transporter protein, score 5.5e-46 216591008986 2 probable transmembrane helices predicted for BCAL1793 by TMHMM2.0 at aa 268-290 and 295-317 216591008987 Membrane bound YbgT-like protein; Region: YbgT_YccB; pfam08173 216591008988 HMMPfam hit to PF08173, Membrane bound YbgT-like protein, score 5e-12 216591008989 1 probable transmembrane helix predicted for BCAL1794 by TMHMM2.0 at aa 2-24 216591008990 AAA domain; Region: AAA_33; pfam13671 216591008991 Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190 216591008992 active site 216591008993 PS00017 ATP/GTP-binding site motif A (P-loop). 216591008994 Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748 216591008995 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591008996 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591008997 HMMPfam hit to PF03435, Saccharopine dehydrogenase, score 3.7e-77 216591008998 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 0.0025 216591008999 HMMPfam hit to PF02254, TrkA-N domain, score 2.8e-07 216591009000 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591009001 AsnC family; Region: AsnC_trans_reg; pfam01037 216591009002 HMMPfam hit to PF01037, AsnC family, score 1.8e-19 216591009003 LTXXQ motif family protein; Region: LTXXQ; pfam07813 216591009004 PGDYG protein; Region: PGDYG; pfam14083 216591009005 Protein of unknown function (DUF3022); Region: DUF3022; pfam11226 216591009006 Putative membrane peptidase family (DUF2324); Region: DUF2324; pfam10086 216591009007 7 probable transmembrane helices predicted for BCAL1801 by TMHMM2.0 at aa 6-28, 41-58, 71-93, 114-136, 175-197, 204-226 and 230-252 216591009008 PS00340 Growth factor and cytokines receptors family signature 2. 216591009009 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591009010 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591009011 DNA binding site [nucleotide binding] 216591009012 domain linker motif; other site 216591009013 Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283 216591009014 putative ligand binding site [chemical binding]; other site 216591009015 putative dimerization interface [polypeptide binding]; other site 216591009016 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591009017 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 3e-06 216591009018 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 8.6e-07 216591009019 Predicted helix-turn-helix motif with score 1673.000, SD 4.89 at aa 12-33, sequence ATISDVAREAGTGKTSVSRYLN 216591009020 bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409 216591009021 D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301 216591009022 dimerization interface [polypeptide binding]; other site 216591009023 ligand binding site [chemical binding]; other site 216591009024 NADP binding site [chemical binding]; other site 216591009025 catalytic site [active] 216591009026 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 4.1e-36 216591009027 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 5.3e-94 216591009028 PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 216591009029 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009030 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591009031 D-galactonate transporter; Region: 2A0114; TIGR00893 216591009032 putative substrate translocation pore; other site 216591009033 12 probable transmembrane helices predicted for BCAL1804 by TMHMM2.0 at aa 7-26, 51-73, 80-99, 104-126, 139-161, 166-188, 231-253, 263-285, 298-317, 322-344, 357-379 and 389-408 216591009034 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 9.6e-61 216591009035 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009036 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 216591009037 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166 216591009038 substrate binding site [chemical binding]; other site 216591009039 ATP binding site [chemical binding]; other site 216591009040 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 3.3e-69 216591009041 PS00584 pfkB family of carbohydrate kinases signature 2. 216591009042 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009043 Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261 216591009044 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 3.8e-07 216591009045 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591009046 aminoethylphosphonate catabolism associated LysR family transcriptional regulator; Region: phn_lysR; TIGR03339 216591009047 C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420 216591009048 putative dimerization interface [polypeptide binding]; other site 216591009049 HMMPfam hit to PF03466, LysR substrate binding domain, score 4e-47 216591009050 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.2e-20 216591009051 Predicted helix-turn-helix motif with score 1494.000, SD 4.28 at aa 16-37, sequence LNISHAAVALHLSQPAVSGQLR 216591009052 Predicted membrane protein [Function unknown]; Region: COG2855 216591009053 PS00041 Bacterial regulatory proteins, araC family signature. 216591009054 9 probable transmembrane helices predicted for BCAL1808 by TMHMM2.0 at aa 20-37, 42-64, 104-126, 136-155, 168-190, 235-252, 273-292, 302-324 and 331-353 216591009055 HMMPfam hit to PF03601, Conserved hypothetical protein, score 2.5e-105 216591009056 putative voltage-gated ClC-type chloride channel ClcB; Provisional; Region: PRK01862 216591009057 CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400 216591009058 Cl- selectivity filter; other site 216591009059 Cl- binding residues [ion binding]; other site 216591009060 pore gating glutamate residue; other site 216591009061 dimer interface [polypeptide binding]; other site 216591009062 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205 216591009063 10 probable transmembrane helices predicted for BCAL1809 by TMHMM2.0 at aa 37-54, 80-102, 178-200, 205-227, 248-270, 290-312, 319-341, 346-368, 380-402 and 412-431 216591009064 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009065 HMMPfam hit to PF00654, Voltage gated chloride channel, score 1.5e-33 216591009066 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009067 HMMPfam hit to PF00571, CBS domain pair, score 1.4e-12 216591009068 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591009069 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591009070 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591009071 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 4e-17 216591009072 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 216591009073 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591009074 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009075 HMMPfam hit to PF00529, HlyD family secretion protein, score 0.00029 216591009076 Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841 216591009077 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 1.5e-67 216591009078 12 probable transmembrane helices predicted for BCAL1812 by TMHMM2.0 at aa 21-43, 342-364, 369-388, 398-420, 432-454, 474-496, 538-560, 871-890, 897-919, 923-945, 966-988 and 998-1020 216591009079 PS00152 ATP synthase alpha and beta subunits signature. 216591009080 PS00589 PTS HPR component serine phosphorylation site signature. 216591009081 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591009082 1 probable transmembrane helix predicted for BCAL1813 by TMHMM2.0 at aa 13-32 216591009083 HMMPfam hit to PF02321, Outer membrane efflux protein, score 9.6e-19 216591009084 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.6e-32 216591009085 Helix-Turn-Helix DNA binding domain of the transcription regulators NolA and AlbR; Region: HTH_NolA-AlbR; cd04788 216591009086 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 216591009087 DNA binding residues [nucleotide binding] 216591009088 putative dimer interface [polypeptide binding]; other site 216591009089 TipAS antibiotic-recognition domain; Region: TipAS; pfam07739 216591009090 TipAS antibiotic-recognition domain; Region: TipAS; pfam07739 216591009091 Predicted helix-turn-helix motif with score 1227.000, SD 3.37 at aa 3-24, sequence LKVGELAKRSGLTVRTLHHYHA 216591009092 HMMPfam hit to PF00376, MerR family regulatory protein, score 1.5e-11 216591009093 HMMPfam hit to PF05583, Albicidin resistance domain, score 4.6e-12 216591009094 HMMPfam hit to PF05583, Albicidin resistance domain, score 2.7e-13 216591009095 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591009096 sequence-specific DNA binding site [nucleotide binding]; other site 216591009097 salt bridge; other site 216591009098 Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 16-37, sequence VRSKDLAAAVGITEQNLSLLKQ 216591009099 Protein of unknown function (DUF2975); Region: DUF2975; pfam11188 216591009100 4 probable transmembrane helices predicted for BCAL1816 by TMHMM2.0 at aa 13-35, 65-87, 117-139 and 149-171 216591009101 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009102 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009103 PAS fold; Region: PAS_4; pfam08448 216591009104 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591009105 putative active site [active] 216591009106 heme pocket [chemical binding]; other site 216591009107 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591009108 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 216591009109 Walker A motif; other site 216591009110 ATP binding site [chemical binding]; other site 216591009111 Walker B motif; other site 216591009112 arginine finger; other site 216591009113 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 0.0036 216591009114 Predicted helix-turn-helix motif with score 2218.000, SD 6.74 at aa 430-451, sequence GTRKALAEQLGLSERTLYRRMK 216591009115 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591009116 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 1.8e-123 216591009117 HMMPfam hit to PF07728, ATPase family associated with various, score 0.00055 216591009118 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591009119 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591009120 HMMPfam hit to PF08448, PAS fold, score 1.8e-21 216591009121 HMMPfam hit to PF00989, PAS fold, score 6.4e-05 216591009122 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 216591009123 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 1.8e-19 216591009124 Putative phosphatase (DUF442); Region: DUF442; cl17385 216591009125 pyridine nucleotide-disulfide oxidoreductase family protein; Region: Nterm_to_SelD; TIGR03169 216591009126 HMMPfam hit to PF04273, Protein of unknown function (DUF442), score 4.4e-42 216591009127 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.0016 216591009128 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 0.00011 216591009129 HMMPfam hit to PF01925, Domain of unknown function DUF81, score 7.7e-22 216591009130 8 probable transmembrane helices predicted for BCAL1820 by TMHMM2.0 at aa 5-27, 42-61, 68-86, 91-113, 141-174, 189-211, 218-235 and 245-267 216591009131 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 216591009132 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591009133 dimer interface [polypeptide binding]; other site 216591009134 conserved gate region; other site 216591009135 putative PBP binding loops; other site 216591009136 ABC-ATPase subunit interface; other site 216591009137 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.8e-13 216591009138 6 probable transmembrane helices predicted for BCAL1821 by TMHMM2.0 at aa 9-31, 65-87, 100-122, 137-159, 180-202 and 239-261 216591009139 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591009140 PS00044 Bacterial regulatory proteins, lysR family signature. 216591009141 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591009142 dimer interface [polypeptide binding]; other site 216591009143 conserved gate region; other site 216591009144 putative PBP binding loops; other site 216591009145 ABC-ATPase subunit interface; other site 216591009146 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3e-21 216591009147 8 probable transmembrane helices predicted for BCAL1822 by TMHMM2.0 at aa 21-43, 66-88, 93-115, 125-147, 177-199, 219-241, 248-267 and 277-299 216591009148 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591009149 putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607 216591009150 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591009151 Walker A/P-loop; other site 216591009152 ATP binding site [chemical binding]; other site 216591009153 Q-loop/lid; other site 216591009154 ABC transporter signature motif; other site 216591009155 Walker B; other site 216591009156 D-loop; other site 216591009157 H-loop/switch region; other site 216591009158 TOBE domain; Region: TOBE_2; pfam08402 216591009159 HMMPfam hit to PF08402, TOBE domain, score 5.3e-19 216591009160 HMMPfam hit to PF00005, ABC transporter, score 2.5e-65 216591009161 PS00211 ABC transporters family signature. 216591009162 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009163 putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682 216591009164 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 216591009165 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 2.5e-14 216591009166 Predicted Fe-S protein [General function prediction only]; Region: COG3313 216591009167 HMMPfam hit to PF06945, Protein of unknown function (DUF1289), score 9.1e-20 216591009168 Protein of unknown function (DUF1120); Region: DUF1120; cl05856 216591009169 HMMPfam hit to PF06551, Protein of unknown function (DUF1120), score 5.8e-28 216591009170 putative fimbrial chaperone protein; Provisional; Region: PRK09918 216591009171 Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345 216591009172 HMMPfam hit to PF00345, Gram-negative pili assembly chaperone, score 1.8e-12 216591009173 putative fimbrial outer membrane usher protein; Provisional; Region: PRK15304 216591009174 PapC N-terminal domain; Region: PapC_N; pfam13954 216591009175 Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577 216591009176 PapC C-terminal domain; Region: PapC_C; pfam13953 216591009177 HMMPfam hit to PF00577, Fimbrial Usher protein, score 1.4e-35 216591009178 Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047 216591009179 HMMPfam hit to PF03922, OmpW family, score 7.4e-50 216591009180 Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070 216591009181 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 216591009182 FMN binding site [chemical binding]; other site 216591009183 substrate binding site [chemical binding]; other site 216591009184 putative catalytic residue [active] 216591009185 HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 8.5e-12 216591009186 Rhodococcus ruber 6-oxolauric acid dehydrogenase-like; Region: ALDH_CddD_SSP0762; cd07138 216591009187 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591009188 NAD binding site [chemical binding]; other site 216591009189 catalytic residues [active] 216591009190 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 9.1e-224 216591009191 PS00070 Aldehyde dehydrogenases cysteine active site. 216591009192 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591009193 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009194 hypothetical protein; Provisional; Region: PRK11667 216591009195 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009196 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009197 Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917 216591009198 NodB motif; other site 216591009199 active site 216591009200 catalytic site [active] 216591009201 metal binding site [ion binding]; metal-binding site 216591009202 HMMPfam hit to PF01522, Polysaccharide deacetylase, score 5e-18 216591009203 Phosphotransferase enzyme family; Region: APH; pfam01636 216591009204 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270 216591009205 Cephalosporin hydroxylase; Region: CmcI; pfam04989 216591009206 HMMPfam hit to PF04989, Cephalosporin hydroxylase, score 1.4e-31 216591009207 Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819 216591009208 This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784 216591009209 active site 216591009210 TDP-binding site; other site 216591009211 acceptor substrate-binding pocket; other site 216591009212 homodimer interface [polypeptide binding]; other site 216591009213 HMMPfam hit to PF00201, UDP-glucoronosyl and UDP-glucosyl tra, score 2e-05 216591009214 HMMPfam hit to PF04101, Glycosyltransferase family, score 0.00077 216591009215 asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536 216591009216 The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the...; Region: Asn_Synthase_B_C; cd01991 216591009217 HMMPfam hit to PF00733, Asparagine synthase, score 7.9e-17 216591009218 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591009219 FeS/SAM binding site; other site 216591009220 Phosphotransferase enzyme family; Region: APH; pfam01636 216591009221 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270 216591009222 substrate binding site [chemical binding]; other site 216591009223 ABC transporter ATP-binding protein; Provisional; Region: PRK15064 216591009224 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 216591009225 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 216591009226 ABC transporter; Region: ABC_tran_2; pfam12848 216591009227 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 216591009228 HMMPfam hit to PF00005, ABC transporter, score 7.7e-42 216591009229 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009230 HMMPfam hit to PF00005, ABC transporter, score 1.1e-42 216591009231 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009232 Lipocalin-like domain; Region: Lipocalin_5; pfam13924 216591009233 Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982 216591009234 AsmA-like C-terminal region; Region: AsmA_2; pfam13502 216591009235 HMMPfam hit to PF05170, AsmA family, score 4.8e-104 216591009236 1 probable transmembrane helix predicted for BCAL1845 by TMHMM2.0 at aa 12-34 216591009237 ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619 216591009238 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591009239 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591009240 Walker A/P-loop; other site 216591009241 Walker A/P-loop; other site 216591009242 ATP binding site [chemical binding]; other site 216591009243 Q-loop/lid; other site 216591009244 ABC transporter signature motif; other site 216591009245 Walker B; other site 216591009246 D-loop; other site 216591009247 H-loop/switch region; other site 216591009248 HMMPfam hit to PF00005, ABC transporter, score 9e-44 216591009249 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009250 ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390 216591009251 HMMPfam hit to PF03649, Uncharacterised protein family (UPF0014), score 2.1e-49 216591009252 7 probable transmembrane helices predicted for BCAL1847 by TMHMM2.0 at aa 10-32, 39-61, 65-87, 99-121, 126-148, 191-213 and 223-245 216591009253 Periplasmic lysozyme inhibitor, I-type (PliI) and similar proteins; Region: PliI_like; cd09632 216591009254 dimer interface [polypeptide binding]; other site 216591009255 putative inhibitory loop; other site 216591009256 1 probable transmembrane helix predicted for BCAL1849 by TMHMM2.0 at aa 41-63 216591009257 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009258 Arginate lyase and other MDR family members; Region: AL_MDR; cd08252 216591009259 zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817 216591009260 putative NAD(P) binding site [chemical binding]; other site 216591009261 dimer interface [polypeptide binding]; other site 216591009262 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 5.5e-19 216591009263 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 3.6e-14 216591009264 transcriptional activator TtdR; Provisional; Region: PRK09801 216591009265 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591009266 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591009267 putative effector binding pocket; other site 216591009268 dimerization interface [polypeptide binding]; other site 216591009269 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.6e-13 216591009270 PS00044 Bacterial regulatory proteins, lysR family signature. 216591009271 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.4e-51 216591009272 Domain of unknown function (DUF4072); Region: DUF4072; pfam13284 216591009273 Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560 216591009274 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591009275 motif II; other site 216591009276 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.1e-23 216591009277 cystathionine beta-lyase; Provisional; Region: PRK07050 216591009278 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 216591009279 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591009280 catalytic residue [active] 216591009281 HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 1.4e-75 216591009282 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009283 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166 216591009284 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 216591009285 substrate binding site [chemical binding]; other site 216591009286 ATP binding site [chemical binding]; other site 216591009287 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 4.9e-64 216591009288 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009289 ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862 216591009290 Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919 216591009291 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591009292 FeS/SAM binding site; other site 216591009293 TRAM domain; Region: TRAM; cl01282 216591009294 HMMPfam hit to PF01938, TRAM domain, score 0.044 216591009295 HMMPfam hit to PF04055, Radical SAM superfamily, score 1.2e-27 216591009296 PS01278 Uncharacterized protein family UPF0004 signature. 216591009297 HMMPfam hit to PF00919, Uncharacterized protein family UPF0004, score 1.6e-34 216591009298 2 probable transmembrane helices predicted for BCAL1857 by TMHMM2.0 at aa 13-35 and 39-61 216591009299 RibD C-terminal domain; Region: RibD_C; cl17279 216591009300 Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262 216591009301 HMMPfam hit to PF01872, RibD C-terminal domain, score 1.2e-13 216591009302 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591009303 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5394 216591009304 PHB/PHA accumulation regulator DNA-binding domain; Region: PHB_acc_N; pfam07879 216591009305 PHB accumulation regulatory domain; Region: PHB_acc; pfam05233 216591009306 HMMPfam hit to PF05233, PHB accumulation regulatory domain, score 2e-16 216591009307 HMMPfam hit to PF05233, PHB accumulation regulatory domain, score 2.3e-19 216591009308 HMMPfam hit to PF07879, PHB/PHA accumulation regulator DNA-binding, score 3.5e-40 216591009309 acetyacetyl-CoA reductase; Provisional; Region: PRK12938 216591009310 beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333 216591009311 NAD(P) binding site [chemical binding]; other site 216591009312 homotetramer interface [polypeptide binding]; other site 216591009313 homodimer interface [polypeptide binding]; other site 216591009314 active site 216591009315 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00036 216591009316 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.5e-37 216591009317 PS00061 Short-chain dehydrogenases/reductases family signature. 216591009318 putative acyltransferase; Provisional; Region: PRK05790 216591009319 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 216591009320 dimer interface [polypeptide binding]; other site 216591009321 active site 216591009322 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 3.8e-85 216591009323 PS00099 Thiolases active site. 216591009324 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009325 PS00737 Thiolases signature 2. 216591009326 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 1.8e-177 216591009327 PS00098 Thiolases acyl-enzyme intermediate signature. 216591009328 poly(R)-hydroxyalkanoic acid synthase, class I; Region: PHA_synth_I; TIGR01838 216591009329 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167 216591009330 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 8.2e-20 216591009331 HMMPfam hit to PF07167, Poly-beta-hydroxybutyrate polymerase (P, score 8.9e-115 216591009332 Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496 216591009333 Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650 216591009334 HMMPfam hit to PF02578, Uncharacterised ACR, YfiH family COG1496, score 4e-61 216591009335 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009336 Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564 216591009337 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 216591009338 RNA binding surface [nucleotide binding]; other site 216591009339 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 216591009340 active site 216591009341 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 8.1e-63 216591009342 PS01129 Rlu family of pseudouridine synthase signature. 216591009343 HMMPfam hit to PF01479, S4 domain, score 1.3e-06 216591009344 outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302 216591009345 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009346 Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199 216591009347 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251 216591009348 DEAD_2; Region: DEAD_2; pfam06733 216591009349 Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199 216591009350 Helicase C-terminal domain; Region: Helicase_C_2; pfam13307 216591009351 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009352 HMMPfam hit to PF04325, Protein of unknown function (DUF465), score 0.0001 216591009353 Transcriptional accessory protein [Transcription]; Region: Tex; COG2183 216591009354 Tex-like protein N-terminal domain; Region: Tex_N; pfam09371 216591009355 Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732 216591009356 S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685 216591009357 RNA binding site [nucleotide binding]; other site 216591009358 HMMPfam hit to PF00575, S1 RNA binding domain, score 6.5e-24 216591009359 K+ transporter [Inorganic ion transport and metabolism]; Region: Kup; COG3158 216591009360 potassium uptake protein; Region: kup; TIGR00794 216591009361 HMMPfam hit to PF02705, K+ potassium transporter, score 1.6e-168 216591009362 12 probable transmembrane helices predicted for BCAL1871 by TMHMM2.0 at aa 5-24, 39-61, 92-114, 129-151, 163-185, 205-227, 239-261, 283-305, 326-348, 358-380, 389-411 and 416-435 216591009363 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009364 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009365 Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236 216591009366 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 216591009367 active site 216591009368 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.1e-09 216591009369 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 216591009370 Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788 216591009371 Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108 216591009372 GDP-binding site [chemical binding]; other site 216591009373 ACT binding site; other site 216591009374 IMP binding site; other site 216591009375 HMMPfam hit to PF00709, Adenylosuccinate synthetase, score 2.6e-296 216591009376 PS00513 Adenylosuccinate synthetase active site. 216591009377 PS01266 Adenylosuccinate synthetase GTP-binding site. 216591009378 ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: PRK12421 216591009379 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773 216591009380 dimer interface [polypeptide binding]; other site 216591009381 motif 1; other site 216591009382 active site 216591009383 motif 2; other site 216591009384 motif 3; other site 216591009385 HMMPfam hit to PF00587, tRNA synthetase class II core domain (G,, score 8.6e-06 216591009386 Uncharacterized protein conserved in bacteria (DUF2065); Region: DUF2065; pfam09838 216591009387 2 probable transmembrane helices predicted for BCAL1875 by TMHMM2.0 at aa 7-29 and 44-61 216591009388 Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330 216591009389 Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405 216591009390 HMMPfam hit to PF01145, SPFH domain / Band, score 1.6e-21 216591009391 1 probable transmembrane helix predicted for BCAL1876 by TMHMM2.0 at aa 5-27 216591009392 Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404 216591009393 HflK protein; Region: hflK; TIGR01933 216591009394 HMMPfam hit to PF01145, SPFH domain / Band, score 3.9e-30 216591009395 1 probable transmembrane helix predicted for BCAL1877 by TMHMM2.0 at aa 89-111 216591009396 GTP-binding protein HflX; Region: GTP_HflX; TIGR03156 216591009397 GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167 216591009398 HflX GTPase family; Region: HflX; cd01878 216591009399 G1 box; other site 216591009400 GTP/Mg2+ binding site [chemical binding]; other site 216591009401 Switch I region; other site 216591009402 G2 box; other site 216591009403 G3 box; other site 216591009404 Switch II region; other site 216591009405 G4 box; other site 216591009406 G5 box; other site 216591009407 HMMPfam hit to PF01926, GTPase of unknown function, score 1.9e-37 216591009408 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009409 bacterial Hfq-like; Region: Hfq; cd01716 216591009410 hexamer interface [polypeptide binding]; other site 216591009411 Sm1 motif; other site 216591009412 RNA binding site [nucleotide binding]; other site 216591009413 Sm2 motif; other site 216591009414 HMMPfam hit to PF01423, LSM domain, score 6.8e-14 216591009415 GTP-binding protein Der; Reviewed; Region: PRK00093 216591009416 EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894 216591009417 G1 box; other site 216591009418 GTP/Mg2+ binding site [chemical binding]; other site 216591009419 Switch I region; other site 216591009420 G2 box; other site 216591009421 Switch II region; other site 216591009422 G3 box; other site 216591009423 G4 box; other site 216591009424 G5 box; other site 216591009425 EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895 216591009426 G1 box; other site 216591009427 GTP/Mg2+ binding site [chemical binding]; other site 216591009428 Switch I region; other site 216591009429 G2 box; other site 216591009430 G3 box; other site 216591009431 Switch II region; other site 216591009432 G4 box; other site 216591009433 G5 box; other site 216591009434 HMMPfam hit to PF01926, GTPase of unknown function, score 6.4e-43 216591009435 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009436 HMMPfam hit to PF01926, GTPase of unknown function, score 5.9e-48 216591009437 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009438 outer membrane assembly lipoprotein YfgL; Region: assembly_YfgL; TIGR03300 216591009439 PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493 216591009440 Trp docking motif [polypeptide binding]; other site 216591009441 active site 216591009442 HMMPfam hit to PF01011, PQQ enzyme repeat, score 7.5e-06 216591009443 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009444 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976 216591009445 Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976 216591009446 1 probable transmembrane helix predicted for BCAL1882 by TMHMM2.0 at aa 15-37 216591009447 histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037 216591009448 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773 216591009449 dimer interface [polypeptide binding]; other site 216591009450 motif 1; other site 216591009451 active site 216591009452 motif 2; other site 216591009453 motif 3; other site 216591009454 HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859 216591009455 anticodon binding site; other site 216591009456 HMMPfam hit to PF03129, Anticodon binding domain, score 1.1e-08 216591009457 HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 1.2e-46 216591009458 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366 216591009459 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694 216591009460 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694 216591009461 HMMPfam hit to PF04551, GcpE protein, score 3.7e-169 216591009462 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591009463 non-specific DNA binding site [nucleotide binding]; other site 216591009464 salt bridge; other site 216591009465 sequence-specific DNA binding site [nucleotide binding]; other site 216591009466 Domain of unknown function (DUF4115); Region: DUF4115; pfam13464 216591009467 1 probable transmembrane helix predicted for BCAL1885 by TMHMM2.0 at aa 134-156 216591009468 ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194 216591009469 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591009470 FeS/SAM binding site; other site 216591009471 HMMPfam hit to PF04055, Radical SAM superfamily, score 1.9e-12 216591009472 Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413 216591009473 active site 216591009474 multimer interface [polypeptide binding]; other site 216591009475 HMMPfam hit to PF00334, Nucleoside diphosphate kinase, score 4.8e-74 216591009476 Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670 216591009477 YccA-like proteins; Region: YccA_like; cd10433 216591009478 HMMPfam hit to PF01027, Uncharacterised protein family UPF0005, score 4.2e-15 216591009479 7 probable transmembrane helices predicted for BCAL1888 by TMHMM2.0 at aa 33-55, 59-81, 88-110, 120-142, 149-171, 175-194 and 207-229 216591009480 23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168 216591009481 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591009482 S-adenosylmethionine binding site [chemical binding]; other site 216591009483 HMMPfam hit to PF05958, tRNA (Uracil-5-)-methyltransferase, score 9.5e-08 216591009484 Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490 216591009485 putative catalytic site [active] 216591009486 putative metal binding site [ion binding]; other site 216591009487 putative phosphate binding site [ion binding]; other site 216591009488 putative catalytic site [active] 216591009489 putative phosphate binding site [ion binding]; other site 216591009490 putative metal binding site [ion binding]; other site 216591009491 HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 3e-19 216591009492 Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782 216591009493 active site 216591009494 catalytic site [active] 216591009495 substrate binding site [chemical binding]; other site 216591009496 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108 216591009497 RNA polymerase sigma factor RpoS; Region: rpoS_proteo; TIGR02394 216591009498 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 216591009499 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591009500 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591009501 DNA binding residues [nucleotide binding] 216591009502 HMMPfam hit to PF04545, Sigma-70, region, score 1.5e-20 216591009503 PS00716 Sigma-70 factors family signature 2. 216591009504 Predicted helix-turn-helix motif with score 1993.000, SD 5.97 at aa 320-341, sequence ATLEELADEMGLTRERVRQIQQ 216591009505 HMMPfam hit to PF04542, Sigma-70 region, score 1.2e-25 216591009506 PS00715 Sigma-70 factors family signature 1. 216591009507 HMMPfam hit to PF00140, Sigma-70 factor, region, score 9.8e-10 216591009508 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 216591009509 Peptidase family M23; Region: Peptidase_M23; pfam01551 216591009510 HMMPfam hit to PF01551, Peptidase family M23, score 9.5e-44 216591009511 HMMPfam hit to PF01476, LysM domain, score 1.1e-13 216591009512 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009513 Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518 216591009514 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591009515 S-adenosylmethionine binding site [chemical binding]; other site 216591009516 HMMPfam hit to PF01135, Protein-L-isoaspartate(D-aspartate) O-methyl, score 1e-67 216591009517 5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346 216591009518 HMMPfam hit to PF01975, Survival protein SurE, score 1.3e-74 216591009519 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591009520 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591009521 HMMPfam hit to PF02515, CoA-transferase family III, score 7.2e-68 216591009522 recombination protein RecR; Reviewed; Region: recR; PRK00076 216591009523 RecR protein; Region: RecR; pfam02132 216591009524 TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR. RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025 216591009525 putative active site [active] 216591009526 putative metal-binding site [ion binding]; other site 216591009527 tetramer interface [polypeptide binding]; other site 216591009528 HMMPfam hit to PF01751, Toprim domain, score 2.5e-10 216591009529 HMMPfam hit to PF02132, RecR protein, score 1.6e-10 216591009530 hypothetical protein; Validated; Region: PRK00153 216591009531 HMMPfam hit to PF02575, Uncharacterised BCR, YbaB family COG0718, score 2.8e-49 216591009532 DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397 216591009533 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591009534 Walker A motif; other site 216591009535 ATP binding site [chemical binding]; other site 216591009536 Walker B motif; other site 216591009537 arginine finger; other site 216591009538 DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169 216591009539 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 6.7e-07 216591009540 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009541 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 216591009542 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591009543 catalytic residues [active] 216591009544 HMMPfam hit to PF00085, Thioredoxin, score 1.3e-51 216591009545 PS00194 Thioredoxin family active site. 216591009546 transcription termination factor Rho; Provisional; Region: rho; PRK09376 216591009547 Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498 216591009548 Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459 216591009549 RNA binding site [nucleotide binding]; other site 216591009550 Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128 216591009551 multimer interface [polypeptide binding]; other site 216591009552 Walker A motif; other site 216591009553 ATP binding site [chemical binding]; other site 216591009554 Walker B motif; other site 216591009555 HMMPfam hit to PF07498, Rho termination factor, N-terminal domai, score 2e-19 216591009556 HMMPfam hit to PF07497, Rho termination factor, RNA-binding doma, score 2.9e-58 216591009557 HMMPfam hit to PF08206, Ribonuclease B OB domain, score 0.00065 216591009558 HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleoti, score 8e-77 216591009559 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009560 Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600 216591009561 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 216591009562 DNA binding residues [nucleotide binding] 216591009563 Predicted helix-turn-helix motif with score 1701.000, SD 4.98 at aa 1-22, sequence MTVSDAASRLGVTPRTLKYYEE 216591009564 HMMPfam hit to PF00376, MerR family regulatory protein, score 3.6e-13 216591009565 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591009566 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591009567 9 probable transmembrane helices predicted for BCAL1903 by TMHMM2.0 at aa 30-52, 89-111, 116-138, 153-171, 178-200, 220-242, 287-306, 321-343 and 433-455 216591009568 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009569 Phosphoenolpyruvate:glucose-phosphotransferase regulator; Region: MtfA; pfam06167 216591009570 HMMPfam hit to PF06167, Protein of unknown function (DUF980), score 3.3e-121 216591009571 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009572 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591009573 50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678 216591009574 HMMPfam hit to PF01197, Ribosomal protein L31, score 4.6e-17 216591009575 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807 216591009576 11 probable transmembrane helices predicted for BCAL1906 by TMHMM2.0 at aa 39-58, 124-146, 196-213, 223-252, 259-281, 320-337, 344-361, 371-388, 401-423, 443-462 and 475-497 216591009577 multidrug efflux protein; Reviewed; Region: PRK01766 216591009578 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131 216591009579 cation binding site [ion binding]; other site 216591009580 12 probable transmembrane helices predicted for BCAL1907 by TMHMM2.0 at aa 9-31, 46-68, 89-106, 126-145, 157-179, 199-221, 242-264, 279-301, 314-336, 346-368, 380-402 and 417-439 216591009581 HMMPfam hit to PF01554, MatE, score 4.2e-37 216591009582 HMMPfam hit to PF01554, MatE, score 1.8e-32 216591009583 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009584 lipoyl synthase; Provisional; Region: PRK05481 216591009585 HMMPfam hit to PF04055, Radical SAM superfamily, score 1.3e-26 216591009586 acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional; Region: PRK14875 216591009587 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 216591009588 E3 interaction surface; other site 216591009589 lipoyl attachment site [posttranslational modification]; other site 216591009590 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.1e-35 216591009591 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 2.9e-10 216591009592 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 216591009593 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022 216591009594 Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036 216591009595 alpha subunit interface [polypeptide binding]; other site 216591009596 TPP binding site [chemical binding]; other site 216591009597 heterodimer interface [polypeptide binding]; other site 216591009598 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 216591009599 HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 1.3e-55 216591009600 HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 1e-78 216591009601 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009602 PS00430 TonB-dependent receptor proteins signature 1. 216591009603 pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182 216591009604 Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000 216591009605 tetramer interface [polypeptide binding]; other site 216591009606 TPP-binding site [chemical binding]; other site 216591009607 heterodimer interface [polypeptide binding]; other site 216591009608 phosphorylation loop region [posttranslational modification] 216591009609 HMMPfam hit to PF00676, Dehydrogenase E1 component, score 1.4e-119 216591009610 3-ketoacyl-(acyl-carrier-protein) reductase; Reviewed; Region: PRK12826 216591009611 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591009612 NAD(P) binding site [chemical binding]; other site 216591009613 active site 216591009614 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0035 216591009615 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.6e-36 216591009616 PS00061 Short-chain dehydrogenases/reductases family signature. 216591009617 Predicted inorganic polyphosphate/ATP-NAD kinase [General function prediction only]; Region: COG3199 216591009618 HMMPfam hit to PF01513, ATP-NAD kinase, score 1.8e-43 216591009619 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591009620 Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284 216591009621 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591009622 Walker A motif; other site 216591009623 ATP binding site [chemical binding]; other site 216591009624 Walker B motif; other site 216591009625 arginine finger; other site 216591009626 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591009627 HMMPfam hit to PF01590, GAF domain, score 8e-08 216591009628 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3.3e-118 216591009629 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591009630 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591009631 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591009632 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 1.3e-13 216591009633 Predicted helix-turn-helix motif with score 1687.000, SD 4.93 at aa 608-629, sequence WRPDAAARALGISRATLYRRIA 216591009634 Carboxymuconolactone decarboxylase family; Region: CMD; cl00460 216591009635 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 2.9e-30 216591009636 Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109 216591009637 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 216591009638 DNA binding residues [nucleotide binding] 216591009639 putative dimer interface [polypeptide binding]; other site 216591009640 HMMPfam hit to PF00376, MerR family regulatory protein, score 1.2e-16 216591009641 PS00552 Bacterial regulatory proteins, merR family signature. 216591009642 Predicted helix-turn-helix motif with score 1978.000, SD 5.92 at aa 14-35, sequence LTIGQVAELTGVSTHTLRYYEQ 216591009643 DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair]; Region: ComEA; COG1555 216591009644 1 probable transmembrane helix predicted for BCAL1917 by TMHMM2.0 at aa 19-38 216591009645 Bacterial protein of unknown function (DUF937); Region: DUF937; cl01528 216591009646 HMMPfam hit to PF06078, Bacterial protein of unknown function (DUF93, score 2.4e-28 216591009647 ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346 216591009648 Clp amino terminal domain; Region: Clp_N; pfam02861 216591009649 Clp amino terminal domain; Region: Clp_N; pfam02861 216591009650 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591009651 Walker A motif; other site 216591009652 ATP binding site [chemical binding]; other site 216591009653 Walker B motif; other site 216591009654 arginine finger; other site 216591009655 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591009656 Walker A motif; other site 216591009657 ATP binding site [chemical binding]; other site 216591009658 Walker B motif; other site 216591009659 arginine finger; other site 216591009660 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 216591009661 HMMPfam hit to PF07724, ATPase family associated with various cellul, score 3.6e-109 216591009662 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 1.3e-05 216591009663 PS00871 Chaperonins clpA/B signature 2. 216591009664 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009665 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 8.4e-14 216591009666 PS00870 Chaperonins clpA/B signature 1. 216591009667 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009668 HMMPfam hit to PF02861, Clp amino terminal domain, score 3.8e-12 216591009669 HMMPfam hit to PF02861, Clp amino terminal domain, score 2.2e-13 216591009670 Transcriptional regulator; Region: Rrf2; cl17282 216591009671 Rrf2 family protein; Region: rrf2_super; TIGR00738 216591009672 HMMPfam hit to PF02082, Transcriptional regulator, score 6.3e-42 216591009673 Predicted helix-turn-helix motif with score 1368.000, SD 3.85 at aa 25-46, sequence ATIQEISDAYGISKNHLMKVVQ 216591009674 superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280 216591009675 heme-binding site [chemical binding]; other site 216591009676 MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756 216591009677 MoaE homodimer interface [polypeptide binding]; other site 216591009678 MoaD interaction [polypeptide binding]; other site 216591009679 active site residues [active] 216591009680 HMMPfam hit to PF02391, MoaE protein, score 1.6e-45 216591009681 Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754 216591009682 MoaE interaction surface [polypeptide binding]; other site 216591009683 MoeB interaction surface [polypeptide binding]; other site 216591009684 thiocarboxylated glycine; other site 216591009685 HMMPfam hit to PF02597, ThiS family, score 1.1e-21 216591009686 Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303 216591009687 MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887 216591009688 dimer interface [polypeptide binding]; other site 216591009689 putative functional site; other site 216591009690 putative MPT binding site; other site 216591009691 HMMPfam hit to PF03454, MoeA C-terminal region (domain IV), score 0.00052 216591009692 HMMPfam hit to PF00994, Probable molybdopterin binding domain, score 1.1e-53 216591009693 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009694 HMMPfam hit to PF03453, MoeA N-terminal region (domain I and II, score 1.2e-64 216591009695 Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498 216591009696 Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560 216591009697 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591009698 catalytic residue [active] 216591009699 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 1.3e-28 216591009700 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 216591009701 homoserine dehydrogenase; Provisional; Region: PRK06349 216591009702 Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447 216591009703 Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742 216591009704 ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881 216591009705 HMMPfam hit to PF01842, ACT domain, score 2.7e-13 216591009706 HMMPfam hit to PF00742, Homoserine dehydrogenase, score 2.3e-99 216591009707 PS01042 Homoserine dehydrogenase signature. 216591009708 HMMPfam hit to PF03447, Homoserine dehydrogenase, NAD binding d, score 2.3e-32 216591009709 aminotransferase AlaT; Validated; Region: PRK09265 216591009710 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591009711 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591009712 homodimer interface [polypeptide binding]; other site 216591009713 catalytic residue [active] 216591009714 HMMPfam hit to PF00155, Aminotransferase class I and II, score 3.6e-42 216591009715 Xcc1710_like family, specific to proteobacteria. Xcc1710 is a hypothetical protein from Xanthomonas campestris pv. campestris str. ATCC 33913, similar to Mth938, a hypothetical protein encoded by the Methanobacterium thermoautotrophicum (Mth) genome; Region: Xcc1710_like; cd05560 216591009716 HMMPfam hit to PF04430, Protein of unknown function (DUF498/DUF598), score 1.1e-36 216591009717 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807 216591009718 Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364 216591009719 HMMPfam hit to PF02366, Dolichyl-phosphate-mannose-protein mannosylt, score 9.4e-17 216591009720 11 probable transmembrane helices predicted for BCAL1929 by TMHMM2.0 at aa 13-32, 89-108, 113-135, 180-202, 215-237, 266-285, 298-320, 325-347, 356-378, 388-410 and 415-437 216591009721 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971 216591009722 4 probable transmembrane helices predicted for BCAL1930 by TMHMM2.0 at aa 5-27, 47-69, 76-98 and 102-121 216591009723 HMMPfam hit to PF00893, Small Multidrug Resistance protein, score 0.0011 216591009724 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009725 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399 216591009726 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 216591009727 inhibitor-cofactor binding pocket; inhibition site 216591009728 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591009729 catalytic residue [active] 216591009730 HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 3.6e-135 216591009731 HMMPfam hit to PF01212, Beta-eliminating lyase, score 1.7e-05 216591009732 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714 216591009733 Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187 216591009734 Ligand binding site; other site 216591009735 Putative Catalytic site; other site 216591009736 DXD motif; other site 216591009737 HMMPfam hit to PF00535, Glycosyl transferase family, score 1.3e-27 216591009738 2 probable transmembrane helices predicted for BCAL1932 by TMHMM2.0 at aa 247-269 and 281-303 216591009739 putative formyltransferase; Provisional; Region: PRK06988 216591009740 Formyltransferase, catalytic core domain; Region: FMT_core; cl00395 216591009741 active site 216591009742 substrate binding site [chemical binding]; other site 216591009743 cosubstrate binding site; other site 216591009744 catalytic site [active] 216591009745 Carboxy-terminal domain of Formyltransferase and similar domains; Region: FMT_C_like; cl14785 216591009746 HMMPfam hit to PF00551, Formyl transferase, score 1.5e-19 216591009747 HMMPfam hit to PF02911, Formyl transferase, C-terminal domain, score 8.4e-14 216591009748 NAD-dependent epimerase/dehydratase family protein; Provisional; Region: PRK11908 216591009749 Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257 216591009750 NAD binding site [chemical binding]; other site 216591009751 substrate binding site [chemical binding]; other site 216591009752 active site 216591009753 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 1.3e-56 216591009754 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/isomera, score 0.002 216591009755 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394 216591009756 Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939 216591009757 putative active site [active] 216591009758 putative catalytic site [active] 216591009759 putative Zn binding site [ion binding]; other site 216591009760 HMMPfam hit to PF01522, Polysaccharide deacetylase, score 0.00018 216591009761 Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017 216591009762 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591009763 catalytic triad [active] 216591009764 HMMPfam hit to PF08534, Redoxin, score 1.1e-11 216591009765 HMMPfam hit to PF00578, AhpC/TSA family, score 3.2e-14 216591009766 NYN ribonuclease and ATPase of PhoH family domains [General function prediction only]; Region: COG1875 216591009767 PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883 216591009768 putative active site [active] 216591009769 PhoH-like protein; Region: PhoH; pfam02562 216591009770 HMMPfam hit to PF02562, PhoH-like protein, score 2.6e-29 216591009771 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009772 outer membrane lipoprotein; Provisional; Region: spr; PRK10838 216591009773 NlpC/P60 family; Region: NLPC_P60; pfam00877 216591009774 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009775 HMMPfam hit to PF00877, NlpC/P60 family, score 9.3e-45 216591009776 Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306 216591009777 9 probable transmembrane helices predicted for BCAL1939 by TMHMM2.0 at aa 5-27, 48-65, 80-99, 101-123, 143-165, 200-217, 222-244, 257-279 and 310-332 216591009778 HMMPfam hit to PF01384, Phosphate transporter family, score 9e-96 216591009779 Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392 216591009780 HMMPfam hit to PF01865, Protein of unknown function DUF47, score 2.2e-16 216591009781 replicative DNA helicase; Provisional; Region: PRK07004 216591009782 DnaB-like helicase N terminal domain; Region: DnaB; pfam00772 216591009783 DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984 216591009784 Walker A motif; other site 216591009785 ATP binding site [chemical binding]; other site 216591009786 Walker B motif; other site 216591009787 DNA binding loops [nucleotide binding] 216591009788 HMMPfam hit to PF03796, DnaB-like helicase C terminal domain, score 2.5e-127 216591009789 Predicted helix-turn-helix motif with score 1297.000, SD 3.60 at aa 354-375, sequence RSLKSLAKELDVPVIALSQLNR 216591009790 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009791 HMMPfam hit to PF00772, DnaB-like helicase N terminal domain, score 1.2e-45 216591009792 50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137 216591009793 Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281 216591009794 Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948 216591009795 HMMPfam hit to PF03948, Ribosomal protein L9, C-terminal domai, score 3.5e-23 216591009796 HMMPfam hit to PF01281, Ribosomal protein L9, N-terminal domai, score 3.2e-25 216591009797 PS00651 Ribosomal protein L9 signature. 216591009798 30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391 216591009799 HMMPfam hit to PF01084, Ribosomal protein S18, score 6.2e-28 216591009800 Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930 216591009801 30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453 216591009802 HMMPfam hit to PF01250, Ribosomal protein S6, score 1.4e-42 216591009803 Putative zinc-finger; Region: zf-HC2; pfam13490 216591009804 Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662 216591009805 RNA polymerase sigma factor; Provisional; Region: PRK12533 216591009806 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591009807 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591009808 DNA binding residues [nucleotide binding] 216591009809 HMMPfam hit to PF04545, Sigma-70, region, score 1.2e-18 216591009810 HMMPfam hit to PF08281, Sigma-70, region, score 1.4e-18 216591009811 Predicted helix-turn-helix motif with score 1167.000, SD 3.16 at aa 154-175, sequence LSYREIAAIVDVPVGTVMSRLA 216591009812 HMMPfam hit to PF04542, Sigma-70 region, score 6.9e-17 216591009813 PS01063 Sigma-70 factors ECF subfamily signature. 216591009814 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591009815 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591009816 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591009817 putative effector binding pocket; other site 216591009818 dimerization interface [polypeptide binding]; other site 216591009819 HMMPfam hit to PF03466, LysR substrate binding domain, score 1e-44 216591009820 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4e-15 216591009821 PS00044 Bacterial regulatory proteins, lysR family signature. 216591009822 Predicted helix-turn-helix motif with score 1009.000, SD 2.62 at aa 17-38, sequence GSLAAAALEEGVSPVVLGRRID 216591009823 glyoxylate carboligase; Provisional; Region: PRK11269 216591009824 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 216591009825 PYR/PP interface [polypeptide binding]; other site 216591009826 dimer interface [polypeptide binding]; other site 216591009827 TPP binding site [chemical binding]; other site 216591009828 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591009829 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629 216591009830 TPP-binding site [chemical binding]; other site 216591009831 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 2.9e-54 216591009832 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 2.1e-34 216591009833 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 3.9e-45 216591009834 PS01067 Protein secE/sec61-gamma signature. 216591009835 hydroxypyruvate isomerase; Region: OH-pyruv-isom; TIGR03234 216591009836 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 1.1e-51 216591009837 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009838 tartronate semialdehyde reductase; Provisional; Region: PRK15059 216591009839 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 216591009840 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 7.8e-70 216591009841 HMMPfam hit to PF03807, NADP oxidoreductase coenzyme F420-depen, score 0.002 216591009842 LysM domain/BON superfamily protein; Provisional; Region: PRK11198 216591009843 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 216591009844 HMMPfam hit to PF01476, LysM domain, score 5.4e-11 216591009845 Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964 216591009846 active site 216591009847 homodimer interface [polypeptide binding]; other site 216591009848 homotetramer interface [polypeptide binding]; other site 216591009849 HMMPfam hit to PF00710, Asparaginase, score 1.4e-133 216591009850 PS00917 Asparaginase / glutaminase active site signature 2. 216591009851 PS00144 Asparaginase / glutaminase active site signature 1. 216591009852 psiF repeat; Region: PsiF_repeat; pfam07769 216591009853 psiF repeat; Region: PsiF_repeat; pfam07769 216591009854 1 probable transmembrane helix predicted for BCAL1954 by TMHMM2.0 at aa 5-24 216591009855 HMMPfam hit to PF07769, psiF repeat, score 1.4e-09 216591009856 HMMPfam hit to PF07769, psiF repeat, score 2.6e-10 216591009857 Domain of unknown function DUF221; Region: DUF221; pfam02714 216591009858 2 probable transmembrane helices predicted for BCAL1955 by TMHMM2.0 at aa 12-31 and 109-131 216591009859 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009860 The SYLF domain (also called DUF500), a novel lipid-binding module; Region: SYLF; cd11524 216591009861 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009862 This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802 216591009863 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591009864 putative ADP-binding pocket [chemical binding]; other site 216591009865 HMMPfam hit to PF00534, Glycosyl transferases group, score 9.3e-23 216591009866 Predicted ATPase [General function prediction only]; Region: COG4637 216591009867 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591009868 Walker A/P-loop; other site 216591009869 ATP binding site [chemical binding]; other site 216591009870 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009871 Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668 216591009872 Mechanosensitive ion channel; Region: MS_channel; pfam00924 216591009873 HMMPfam hit to PF00924, Mechanosensitive ion channel, score 7e-14 216591009874 4 probable transmembrane helices predicted for BCAL1959 by TMHMM2.0 at aa 15-34, 55-77, 92-114 and 140-162 216591009875 Ankyrin repeats (3 copies); Region: Ank_2; pfam12796 216591009876 ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204 216591009877 Ankyrin repeats (3 copies); Region: Ank_2; pfam12796 216591009878 HMMPfam hit to PF00023, Ankyrin repeat, score 7.2e-10 216591009879 HMMPfam hit to PF00023, Ankyrin repeat, score 1.2 216591009880 HMMPfam hit to PF00023, Ankyrin repeat, score 5.3e-06 216591009881 1 probable transmembrane helix predicted for BCAL1961 by TMHMM2.0 at aa 12-34 216591009882 TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310 216591009883 active site 216591009884 HMMPfam hit to PF01026, TatD related DNase, score 2.6e-111 216591009885 PS01091 Uncharacterized protein family UPF0006 signature 3. 216591009886 PS01137 Uncharacterized protein family UPF0006 signature 1. 216591009887 DNA polymerase III subunit delta'; Validated; Region: PRK06964 216591009888 DNA polymerase III subunit delta'; Validated; Region: PRK08485 216591009889 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009890 thymidylate kinase; Validated; Region: tmk; PRK00698 216591009891 Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672 216591009892 TMP-binding site; other site 216591009893 ATP-binding site [chemical binding]; other site 216591009894 HMMPfam hit to PF02223, Thymidylate kinase, score 4.3e-55 216591009895 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009896 YceG-like family; Region: YceG; pfam02618 216591009897 proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010 216591009898 dimerization interface [polypeptide binding]; other site 216591009899 HMMPfam hit to PF02618, Aminodeoxychorismate lyase, score 8.8e-134 216591009900 1 probable transmembrane helix predicted for BCAL1965 by TMHMM2.0 at aa 7-29 216591009901 Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354 216591009902 folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317 216591009903 HMMPfam hit to PF01571, Glycine cleavage T-protein (aminomethyl tran, score 2.1e-08 216591009904 NRDE protein; Region: NRDE; cl01315 216591009905 HMMPfam hit to PF05742, Protein of unknown function (DUF833), score 1.4e-72 216591009906 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591009907 Coenzyme A binding pocket [chemical binding]; other site 216591009908 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.4e-10 216591009909 Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312 216591009910 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 216591009911 substrate binding pocket [chemical binding]; other site 216591009912 HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 1.7e-98 216591009913 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 216591009914 CoenzymeA binding site [chemical binding]; other site 216591009915 subunit interaction site [polypeptide binding]; other site 216591009916 PHB binding site; other site 216591009917 HMMPfam hit to PF03061, Thioesterase superfamily, score 2.4e-14 216591009918 Stress responsive A/B Barrel Domain; Region: Dabb; smart00886 216591009919 HMMPfam hit to PF07876, Stress responsive A/B Barrel Domain, score 8.1e-25 216591009920 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 216591009921 homotrimer interaction site [polypeptide binding]; other site 216591009922 putative active site [active] 216591009923 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 1.4e-23 216591009924 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591009925 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591009926 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591009927 metal binding site [ion binding]; metal-binding site 216591009928 active site 216591009929 I-site; other site 216591009930 HMMPfam hit to PF00990, GGDEF domain, score 8e-55 216591009931 8 probable transmembrane helices predicted for BCAL1975 by TMHMM2.0 at aa 21-43, 58-78, 85-107, 117-139, 152-174, 184-203, 210-232 and 236-258 216591009932 acetyl-CoA acetyltransferase; Provisional; Region: PRK07108 216591009933 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 216591009934 dimer interface [polypeptide binding]; other site 216591009935 active site 216591009936 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 2.3e-62 216591009937 PS00737 Thiolases signature 2. 216591009938 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 6.3e-88 216591009939 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591009940 PS00098 Thiolases acyl-enzyme intermediate signature. 216591009941 Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011 216591009942 Isochorismatase family; Region: Isochorismatase; pfam00857 216591009943 catalytic triad [active] 216591009944 metal binding site [ion binding]; metal-binding site 216591009945 conserved cis-peptide bond; other site 216591009946 HMMPfam hit to PF00857, Isochorismatase family, score 3.7e-15 216591009947 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591009948 multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154 216591009949 substrate binding site [chemical binding]; other site 216591009950 oxyanion hole (OAH) forming residues; other site 216591009951 trimer interface [polypeptide binding]; other site 216591009952 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 216591009953 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 216591009954 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 216591009955 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 4.3e-37 216591009956 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD binding, score 4.1e-93 216591009957 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 7.3e-50 216591009958 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07008 216591009959 Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles; Region: ttLC_FACS_AlkK_like; cd12119 216591009960 dimer interface [polypeptide binding]; other site 216591009961 acyl-activating enzyme (AAE) consensus motif; other site 216591009962 putative active site [active] 216591009963 AMP binding site [chemical binding]; other site 216591009964 putative CoA binding site [chemical binding]; other site 216591009965 HMMPfam hit to PF00501, AMP-binding enzyme, score 9.2e-99 216591009966 PS00017 ATP/GTP-binding site motif A (P-loop). 216591009967 PS00455 Putative AMP-binding domain signature. 216591009968 PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 216591009969 Uncharacterized conserved protein [Function unknown]; Region: COG0397 216591009970 hypothetical protein; Validated; Region: PRK00029 216591009971 HMMPfam hit to PF02696, Uncharacterized ACR, YdiU/UPF0061 family, score 7.6e-108 216591009972 methionine sulfoxide reductase B; Provisional; Region: PRK00222 216591009973 SelR domain; Region: SelR; pfam01641 216591009974 HMMPfam hit to PF01641, SelR domain, score 2.7e-78 216591009975 intracellular septation protein A; Reviewed; Region: PRK00259 216591009976 HMMPfam hit to PF04279, Intracellular septation protein A, score 1.6e-78 216591009977 5 probable transmembrane helices predicted for BCAL1983 by TMHMM2.0 at aa 12-34, 49-68, 80-97, 119-141 and 146-168 216591009978 BolA-like protein; Region: BolA; pfam01722 216591009979 HMMPfam hit to PF01722, BolA-like protein, score 2.8e-26 216591009980 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 216591009981 HMMPfam hit to PF00639, PPIC-type PPIASE domain, score 4e-37 216591009982 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591009983 Coenzyme A binding pocket [chemical binding]; other site 216591009984 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.4e-14 216591009985 phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297 216591009986 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203 216591009987 dimerization interface [polypeptide binding]; other site 216591009988 ATP binding site [chemical binding]; other site 216591009989 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204 216591009990 dimerization interface [polypeptide binding]; other site 216591009991 ATP binding site [chemical binding]; other site 216591009992 Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740 216591009993 putative active site [active] 216591009994 catalytic triad [active] 216591009995 HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 4.1e-22 216591009996 HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 2.8e-34 216591009997 HMMPfam hit to PF00586, AIR synthase related protein, N-terminal dom, score 3.2e-21 216591009998 D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711 216591009999 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.5e-54 216591010000 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010001 YjeF-related protein N-terminus; Region: YjeF_N; pfam03853 216591010002 B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171 216591010003 putative substrate binding site [chemical binding]; other site 216591010004 putative ATP binding site [chemical binding]; other site 216591010005 HMMPfam hit to PF03853, YjeF-related protein N-terminus, score 1.8e-27 216591010006 PS01067 Protein secE/sec61-gamma signature. 216591010007 HMMPfam hit to PF01256, Carbohydrate kinase, score 1.7e-60 216591010008 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010009 glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179 216591010010 Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015 216591010011 active site 216591010012 dimer interface [polypeptide binding]; other site 216591010013 Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016 216591010014 dimer interface [polypeptide binding]; other site 216591010015 active site 216591010016 HMMPfam hit to PF00342, Phosphoglucose isomerase, score 1.8e-237 216591010017 PS00765 Phosphoglucose isomerase signature 1. 216591010018 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG4181 216591010019 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 216591010020 Walker A/P-loop; other site 216591010021 ATP binding site [chemical binding]; other site 216591010022 Q-loop/lid; other site 216591010023 ABC transporter signature motif; other site 216591010024 Walker B; other site 216591010025 D-loop; other site 216591010026 H-loop/switch region; other site 216591010027 HMMPfam hit to PF00005, ABC transporter, score 9.9e-61 216591010028 PS00211 ABC transporters family signature. 216591010029 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010030 Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822 216591010031 active site 216591010032 catalytic triad [active] 216591010033 oxyanion hole [active] 216591010034 switch loop; other site 216591010035 HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 1.9e-26 216591010036 SurA N-terminal domain; Region: SurA_N_3; cl07813 216591010037 periplasmic folding chaperone; Provisional; Region: PRK10788 216591010038 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 216591010039 HMMPfam hit to PF00639, PPIC-type PPIASE domain, score 1.3e-26 216591010040 1 probable transmembrane helix predicted for BCAL1993 by TMHMM2.0 at aa 13-32 216591010041 ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466 216591010042 Found in ATP-dependent protease La (LON); Region: LON; smart00464 216591010043 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591010044 Walker A motif; other site 216591010045 ATP binding site [chemical binding]; other site 216591010046 Walker B motif; other site 216591010047 arginine finger; other site 216591010048 Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362 216591010049 HMMPfam hit to PF05362, Lon protease (S16) C-terminal proteolytic do, score 2.8e-150 216591010050 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.1e-45 216591010051 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 1.6e-06 216591010052 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010053 HMMPfam hit to PF02190, ATP-dependent protease La (LON) domain, score 1.8e-38 216591010054 ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342 216591010055 ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689 216591010056 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591010057 Walker A motif; other site 216591010058 ATP binding site [chemical binding]; other site 216591010059 Walker B motif; other site 216591010060 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 216591010061 HMMPfam hit to PF07724, ATPase family associated with various cell, score 8.3e-82 216591010062 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010063 HMMPfam hit to PF06689, ClpX C4-type zinc finger, score 3.3e-26 216591010064 Clp protease; Region: CLP_protease; pfam00574 216591010065 Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017 216591010066 oligomer interface [polypeptide binding]; other site 216591010067 active site residues [active] 216591010068 HMMPfam hit to PF00574, Clp protease, score 7.6e-139 216591010069 PS00382 Endopeptidase Clp histidine active site. 216591010070 PS00381 Endopeptidase Clp serine active site. 216591010071 trigger factor; Provisional; Region: tig; PRK01490 216591010072 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 216591010073 Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698 216591010074 HMMPfam hit to PF05698, Bacterial trigger factor protein (TF) C-ter, score 1.8e-52 216591010075 HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomera, score 4.2e-24 216591010076 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010077 HMMPfam hit to PF05697, Bacterial trigger factor protein (TF), score 2.7e-48 216591010078 Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929 216591010079 HMMPfam hit to PF02595, Glycerate kinase family, score 1.2e-79 216591010080 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591010081 MarR family; Region: MarR_2; pfam12802 216591010082 MarR family; Region: MarR_2; cl17246 216591010083 HMMPfam hit to PF01047, MarR family, score 9.9e-15 216591010084 Predicted helix-turn-helix motif with score 1109.000, SD 2.96 at aa 54-75, sequence FSIMDLARHTNLDKSQASRAAE 216591010085 2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522 216591010086 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 216591010087 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 216591010088 HMMPfam hit to PF08546, Ketopantoate reductase PanE/ApbA C ter, score 4.7e-41 216591010089 HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 2.2e-23 216591010090 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 0.00064 216591010091 1 probable transmembrane helix predicted for BCAL2000 by TMHMM2.0 at aa 7-29 216591010092 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591010093 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591010094 dimerization interface [polypeptide binding]; other site 216591010095 DNA binding residues [nucleotide binding] 216591010096 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 6.6e-10 216591010097 HMMPfam hit to PF04545, Sigma-70, region, score 7.3e-06 216591010098 HMMPfam hit to PF04967, HTH DNA binding domain, score 0.0013 216591010099 HMMPfam hit to PF08281, Sigma-70, region, score 5.7e-07 216591010100 Predicted helix-turn-helix motif with score 1898.000, SD 5.65 at aa 323-344, sequence RSHKEVAQQMAISPTTVRHYLR 216591010101 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591010102 trimer interface [polypeptide binding]; other site 216591010103 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591010104 eyelet of channel; other site 216591010105 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010106 HMMPfam hit to PF00267, Gram-negative porin, score 0.00014 216591010107 PS00213 Lipocalin signature. 216591010108 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 9.9e-20 216591010109 12 probable transmembrane helices predicted for BCAL2003 by TMHMM2.0 at aa 23-45, 60-82, 89-111, 116-138, 145-167, 177-199, 219-241, 256-278, 285-302, 312-334, 341-363 and 368-387 216591010110 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010111 Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII_1; cd09996 216591010112 Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123 216591010113 active site 216591010114 Zn binding site [ion binding]; other site 216591010115 HMMPfam hit to PF00850, Histone deacetylase domain, score 7.7e-79 216591010116 2 probable transmembrane helices predicted for BCAL2005 by TMHMM2.0 at aa 21-43 and 53-75 216591010117 Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683 216591010118 active site lid residues [active] 216591010119 substrate binding pocket [chemical binding]; other site 216591010120 catalytic residues [active] 216591010121 substrate-Mg2+ binding site; other site 216591010122 aspartate-rich region 1; other site 216591010123 aspartate-rich region 2; other site 216591010124 HMMPfam hit to PF00494, Squalene/phytoene synthase, score 2e-08 216591010125 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102 216591010126 HMMPfam hit to PF07394, Protein of unknown function (DUF1501), score 8.7e-23 216591010127 Protein of unknown function (DUF1800); Region: DUF1800; pfam08811 216591010128 PS00116 DNA polymerase family B signature. 216591010129 osmolarity response regulator; Provisional; Region: ompR; PRK09468 216591010130 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591010131 active site 216591010132 phosphorylation site [posttranslational modification] 216591010133 intermolecular recognition site; other site 216591010134 dimerization interface [polypeptide binding]; other site 216591010135 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591010136 DNA binding site [nucleotide binding] 216591010137 HMMPfam hit to PF00072, Response regulator receiver domain, score 9.2e-43 216591010138 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 7.2e-23 216591010139 osmolarity sensor protein; Provisional; Region: envZ; PRK09467 216591010140 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591010141 dimer interface [polypeptide binding]; other site 216591010142 phosphorylation site [posttranslational modification] 216591010143 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591010144 ATP binding site [chemical binding]; other site 216591010145 Mg2+ binding site [ion binding]; other site 216591010146 G-X-G motif; other site 216591010147 2 probable transmembrane helices predicted for BCAL2012 by TMHMM2.0 at aa 15-37 and 161-183 216591010148 HMMPfam hit to PF00672, HAMP domain, score 2e-08 216591010149 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.9e-09 216591010150 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1e-30 216591010151 Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450 216591010152 Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015 216591010153 dimer interface [polypeptide binding]; other site 216591010154 decamer (pentamer of dimers) interface [polypeptide binding]; other site 216591010155 catalytic triad [active] 216591010156 peroxidatic and resolving cysteines [active] 216591010157 HMMPfam hit to PF08534, Redoxin, score 0.00056 216591010158 HMMPfam hit to PF00578, AhpC/TSA family, score 1.1e-34 216591010159 alkylhydroperoxidase, AhpD family; Region: ahpD; TIGR00777 216591010160 Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627 216591010161 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 7.3e-12 216591010162 MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554 216591010163 homotrimer interaction site [polypeptide binding]; other site 216591010164 zinc binding site [ion binding]; other site 216591010165 CDP-binding sites; other site 216591010166 HMMPfam hit to PF02542, YgbB family, score 3.5e-85 216591010167 CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516 216591010168 substrate binding site; other site 216591010169 dimer interface; other site 216591010170 HMMPfam hit to PF01128, Uncharacterized protein family UPF0007, score 2.1e-64 216591010171 PS01295 Uncharacterized protein family UPF0007 signature. 216591010172 Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197 216591010173 CarD-like/TRCF domain; Region: CarD_TRCF; smart01058 216591010174 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 216591010175 ATP binding site [chemical binding]; other site 216591010176 putative Mg++ binding site [ion binding]; other site 216591010177 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591010178 nucleotide binding region [chemical binding]; other site 216591010179 ATP-binding site [chemical binding]; other site 216591010180 This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982 216591010181 HMMPfam hit to PF02559, CarD-like/TRCF domain, score 1.9e-47 216591010182 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 1e-05 216591010183 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1.2e-36 216591010184 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010185 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.5e-19 216591010186 HMMPfam hit to PF03461, TRCF domain, score 2.9e-35 216591010187 acetylornithine deacetylase; Provisional; Region: PRK07522 216591010188 M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894 216591010189 metal binding site [ion binding]; metal-binding site 216591010190 putative dimer interface [polypeptide binding]; other site 216591010191 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 1.7e-49 216591010192 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 2.1e-30 216591010193 Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171 216591010194 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 216591010195 tetramer interface [polypeptide binding]; other site 216591010196 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591010197 catalytic residue [active] 216591010198 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 7.6e-58 216591010199 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 216591010200 Protein of unknown function (DUF3574); Region: DUF3574; pfam12098 216591010201 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010202 Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009 216591010203 Transglycosylase; Region: Transgly; pfam00912 216591010204 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 216591010205 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 2.1e-25 216591010206 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591010207 HMMPfam hit to PF00912, Transglycosylase, score 3e-89 216591010208 1 probable transmembrane helix predicted for BCAL2021 by TMHMM2.0 at aa 61-83 216591010209 Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842 216591010210 HMMPfam hit to PF04012, PspA/IM30 family, score 7e-26 216591010211 Tetratricopeptide repeat; Region: TPR_16; pfam13432 216591010212 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429 216591010213 TPR motif; other site 216591010214 1 probable transmembrane helix predicted for BCAL2023 by TMHMM2.0 at aa 140-162 216591010215 large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952 216591010216 large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567 216591010217 HMMPfam hit to PF01741, Large-conductance mechanosensitive channel,, score 1.3e-54 216591010218 1 probable transmembrane helix predicted for BCAL2024 by TMHMM2.0 at aa 85-107 216591010219 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084 216591010220 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 216591010221 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 7.2e-62 216591010222 Dodecin; Region: Dodecin; pfam07311 216591010223 HMMPfam hit to PF07311, Protein of unknown function (DUF1458), score 1.6e-39 216591010224 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010225 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591010226 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591010227 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_4; cd08463 216591010228 putative substrate binding pocket [chemical binding]; other site 216591010229 putative dimerization interface [polypeptide binding]; other site 216591010230 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.5e-16 216591010231 Predicted helix-turn-helix motif with score 1334.000, SD 3.73 at aa 23-44, sequence RSVTRAAVKLNQSQPAISAALR 216591010232 PS00044 Bacterial regulatory proteins, lysR family signature. 216591010233 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.6e-19 216591010234 hydroxydechloroatrazine ethylaminohydrolase; Reviewed; Region: PRK08203 216591010235 TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298 216591010236 active site 216591010237 putative substrate binding pocket [chemical binding]; other site 216591010238 HMMPfam hit to PF01979, Amidohydrolase family, score 6e-57 216591010239 HMMPfam hit to PF07969, Amidohydrolase family, score 0.00014 216591010240 HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822 216591010241 active site 216591010242 homotetramer interface [polypeptide binding]; other site 216591010243 HMMPfam hit to PF00576, Transthyretin precursor (formerly preal, score 4.4e-64 216591010244 Predicted membrane protein [Function unknown]; Region: COG3748 216591010245 Protein of unknown function (DUF989); Region: DUF989; pfam06181 216591010246 Cytochrome c; Region: Cytochrom_C; pfam00034 216591010247 HMMPfam hit to PF06181, Protein of unknown function (DUF989), score 7.5e-211 216591010248 8 probable transmembrane helices predicted for BCAL2031 by TMHMM2.0 at aa 15-34, 89-111, 121-138, 151-173, 177-199, 226-248, 253-272 and 279-298 216591010249 PS00190 Cytochrome c family heme-binding site signature. 216591010250 ACT domain; Region: ACT_3; pfam10000 216591010251 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3602 216591010252 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591010253 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591010254 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591010255 dimerization interface [polypeptide binding]; other site 216591010256 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.3e-28 216591010257 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.4e-19 216591010258 PS00044 Bacterial regulatory proteins, lysR family signature. 216591010259 Predicted helix-turn-helix motif with score 1883.000, SD 5.60 at aa 18-39, sequence LNFSRAADEVGLTPAAVSHQIK 216591010260 hypothetical protein; Provisional; Region: PRK09266 216591010261 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115 216591010262 substrate-cofactor binding pocket; other site 216591010263 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591010264 homodimer interface [polypeptide binding]; other site 216591010265 catalytic residue [active] 216591010266 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cl10015 216591010267 homotrimer interaction site [polypeptide binding]; other site 216591010268 putative active site [active] 216591010269 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591010270 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 3.9e-31 216591010271 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591010272 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591010273 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472 216591010274 putative effector binding pocket; other site 216591010275 putative dimerization interface [polypeptide binding]; other site 216591010276 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.3e-15 216591010277 Predicted helix-turn-helix motif with score 1815.000, SD 5.37 at aa 11-32, sequence GSFTKAADTLHMSRTTVTQLVQ 216591010278 PS00044 Bacterial regulatory proteins, lysR family signature. 216591010279 HMMPfam hit to PF03466, LysR substrate binding domain, score 5.3e-45 216591010280 ureidoglycolate hydrolase; Provisional; Region: PRK03606 216591010281 Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194 216591010282 HMMPfam hit to PF04115, Ureidoglycolate hydrolase, score 5.3e-90 216591010283 allantoicase; Provisional; Region: PRK13257 216591010284 Allantoicase repeat; Region: Allantoicase; pfam03561 216591010285 Allantoicase repeat; Region: Allantoicase; pfam03561 216591010286 HMMPfam hit to PF03561, Allantoicase repeat, score 6.1e-78 216591010287 HMMPfam hit to PF03561, Allantoicase repeat, score 3.5e-82 216591010288 OHCU decarboxylase; Region: UHCUDC; TIGR03164 216591010289 putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212 216591010290 Catalytic domain of bacterial PuuE allantoinases, Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1), and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977 216591010291 active site 216591010292 catalytic site [active] 216591010293 tetramer interface [polypeptide binding]; other site 216591010294 HMMPfam hit to PF01522, Polysaccharide deacetylase, score 6e-15 216591010295 Hydantoin racemase [Amino acid transport and metabolism]; Region: COG4126 216591010296 HMMPfam hit to PF01177, Asp/Glu/Hydantoin racemase, score 1.3e-06 216591010297 uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain; Region: SLC-NCS1sbd_u1; cd11555 216591010298 Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133 216591010299 Na binding site [ion binding]; other site 216591010300 putative substrate binding site [chemical binding]; other site 216591010301 12 probable transmembrane helices predicted for BCAL2042 by TMHMM2.0 at aa 87-109, 114-136, 168-190, 205-227, 239-261, 281-303, 323-345, 365-387, 400-422, 432-454, 483-505 and 509-526 216591010302 HMMPfam hit to PF02133, Permease for cytosine/purines, uracil,, score 1.3e-80 216591010303 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010304 Transcriptional regulators [Transcription]; Region: GntR; COG1802 216591010305 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591010306 DNA-binding site [nucleotide binding]; DNA binding site 216591010307 FCD domain; Region: FCD; pfam07729 216591010308 HMMPfam hit to PF07729, FCD domain, score 3.6e-19 216591010309 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.5e-18 216591010310 PS00043 Bacterial regulatory proteins, gntR family signature. 216591010311 Predicted helix-turn-helix motif with score 1514.000, SD 4.34 at aa 39-60, sequence LTEAQLCDVFGVKRGTIRQALA 216591010312 LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025 216591010313 dimer interface [polypeptide binding]; other site 216591010314 catalytic triad [active] 216591010315 HMMPfam hit to PF02016, LD-carboxypeptidase, score 2.7e-51 216591010316 Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285 216591010317 nucleoside/Zn binding site; other site 216591010318 dimer interface [polypeptide binding]; other site 216591010319 catalytic motif [active] 216591010320 HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 2.3e-39 216591010321 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 216591010322 Domain of unknown function (DUF1992); Region: DUF1992; cl08096 216591010323 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591010324 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591010325 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591010326 putative substrate translocation pore; other site 216591010327 12 probable transmembrane helices predicted for BCAL2047 by TMHMM2.0 at aa 21-43, 58-80, 85-107, 117-139, 146-168, 178-197, 237-259, 269-291, 303-320, 325-347, 360-382 and 392-414 216591010328 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.3e-49 216591010329 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591010330 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010331 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 216591010332 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591010333 DNA-binding site [nucleotide binding]; DNA binding site 216591010334 UTRA domain; Region: UTRA; pfam07702 216591010335 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 5.8e-25 216591010336 Predicted helix-turn-helix motif with score 1095.000, SD 2.92 at aa 38-59, sequence PSEHELCAMFDVSRITVRQALG 216591010337 HMMPfam hit to PF07702, UTRA domain, score 3.5e-46 216591010338 putative oxidoreductase; Provisional; Region: PRK08275 216591010339 L-aspartate oxidase; Provisional; Region: PRK06175 216591010340 Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910 216591010341 HMMPfam hit to PF00890, FAD binding domain, score 2e-10 216591010342 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidore, score 0.0013 216591010343 HMMPfam hit to PF02910, Fumarate reductase/succinate dehydroge, score 1.1e-05 216591010344 RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409 216591010345 4Fe-4S dicluster domain; Region: Fer4_7; pfam12838 216591010346 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0021 216591010347 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00029 216591010348 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591010349 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 216591010350 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432 216591010351 substrate binding pocket [chemical binding]; other site 216591010352 membrane-bound complex binding site; other site 216591010353 NosL; Region: NosL; cl01769 216591010354 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591010355 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591010356 dimer interface [polypeptide binding]; other site 216591010357 conserved gate region; other site 216591010358 putative PBP binding loops; other site 216591010359 ABC-ATPase subunit interface; other site 216591010360 6 probable transmembrane helices predicted for BCAL2052 by TMHMM2.0 at aa 39-56, 97-119, 132-151, 156-175, 196-218 and 255-273 216591010361 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.6e-18 216591010362 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 216591010363 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 216591010364 Walker A/P-loop; other site 216591010365 ATP binding site [chemical binding]; other site 216591010366 Q-loop/lid; other site 216591010367 ABC transporter signature motif; other site 216591010368 Walker B; other site 216591010369 D-loop; other site 216591010370 H-loop/switch region; other site 216591010371 HMMPfam hit to PF00005, ABC transporter, score 2.7e-59 216591010372 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010373 PS00211 ABC transporters family signature. 216591010374 HEAT repeats; Region: HEAT_2; pfam13646 216591010375 FOG: HEAT repeat [Energy production and conversion]; Region: COG1413 216591010376 HMMPfam hit to PF03130, PBS lyase HEAT-like repeat, score 0.018 216591010377 HMMPfam hit to PF02985, HEAT repeat, score 0.0013 216591010378 HMMPfam hit to PF03130, PBS lyase HEAT-like repeat, score 0.05 216591010379 HMMPfam hit to PF03130, PBS lyase HEAT-like repeat, score 0.00019 216591010380 HMMPfam hit to PF02985, HEAT repeat, score 1.6 216591010381 HMMPfam hit to PF03130, PBS lyase HEAT-like repeat, score 7.9e-05 216591010382 HMMPfam hit to PF03130, PBS lyase HEAT-like repeat, score 2.9e-05 216591010383 HMMPfam hit to PF02985, HEAT repeat, score 0.061 216591010384 Protein of unknown function (DUF971); Region: DUF971; pfam06155 216591010385 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 216591010386 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084 216591010387 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 1.1e-36 216591010388 PS00895 3-hydroxyisobutyrate dehydrogenase signature. 216591010389 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_15; cd04673 216591010390 nudix motif; other site 216591010391 HMMPfam hit to PF00293, NUDIX domain, score 5.4e-27 216591010392 PS00893 mutT domain signature. 216591010393 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 216591010394 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591010395 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 216591010396 Coenzyme A binding pocket [chemical binding]; other site 216591010397 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2e-16 216591010398 2'-5' RNA ligase [Translation, ribosomal structure and biogenesis]; Region: LigT; COG1514 216591010399 HMMPfam hit to PF02834, 2',5' RNA ligase family, score 0.0002 216591010400 DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127 216591010401 active site 216591010402 catalytic site [active] 216591010403 substrate binding site [chemical binding]; other site 216591010404 HMMPfam hit to PF00929, Exonuclease, score 2.5e-25 216591010405 GMP synthase; Reviewed; Region: guaA; PRK00074 216591010406 Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742 216591010407 AMP/PPi binding site [chemical binding]; other site 216591010408 candidate oxyanion hole; other site 216591010409 catalytic triad [active] 216591010410 potential glutamine specificity residues [chemical binding]; other site 216591010411 The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997 216591010412 ATP Binding subdomain [chemical binding]; other site 216591010413 Ligand Binding sites [chemical binding]; other site 216591010414 Dimerization subdomain; other site 216591010415 HMMPfam hit to PF00958, GMP synthase C terminal domain, score 1.6e-47 216591010416 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010417 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 1.7e-38 216591010418 PS00442 Glutamine amidotransferases class-I active site. 216591010419 4 probable transmembrane helices predicted for BCAL2062 by TMHMM2.0 at aa 7-29, 44-66, 73-95 and 105-127 216591010420 inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567 216591010421 TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186 216591010422 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601 216591010423 IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381 216591010424 active site 216591010425 HMMPfam hit to PF00478, IMP dehydrogenase / GMP reductase domain, score 5e-240 216591010426 PS00487 IMP dehydrogenase / GMP reductase signature. 216591010427 HMMPfam hit to PF00571, CBS domain pair, score 1.7e-26 216591010428 Predicted metal-binding integral membrane protein (DUF2182); Region: DUF2182; pfam09948 216591010429 6 probable transmembrane helices predicted for BCAL2064 by TMHMM2.0 at aa 13-35, 72-94, 107-129, 144-166, 214-236 and 246-268 216591010430 Bacterial protein of unknown function (DUF899); Region: DUF899; pfam05988 216591010431 HMMPfam hit to PF05988, Bacterial protein of unknown function (DUF89, score 2.8e-140 216591010432 putative DNA-binding protein (pseudogene);CDS contains a frameshift after codon 48. Similar to Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) hypothetical protein UniProt:Q46WC1 (EMBL:CP000090) (407 aa) fasta scores: E()=1.9e-96, 73.153% id in 406 aa 216591010433 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591010434 HMMPfam hit to PF08279, HTH domain, score 0.0026 216591010435 Predicted helix-turn-helix motif with score 1378.000, SD 3.88 at aa 316-337, sequence WSSSALALALGASQRTVQRALD 216591010436 Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823 216591010437 Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823 216591010438 10 probable transmembrane helices predicted for BCAL2068 by TMHMM2.0 at aa 5-24, 39-58, 65-84, 89-111, 118-140, 155-177, 190-212, 227-249, 256-278 and 283-302 216591010439 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.5e-05 216591010440 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2914 216591010441 HMMPfam hit to PF03658, Uncharacterised protein family (UPF0125), score 6.8e-39 216591010442 Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813 216591010443 putative coenzyme Q binding site [chemical binding]; other site 216591010444 HMMPfam hit to PF03364, Streptomyces cyclase/dehydrase, score 9e-45 216591010445 Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294 216591010446 SmpB-tmRNA interface; other site 216591010447 HMMPfam hit to PF01668, SmpB protein, score 3.8e-37 216591010448 PS01317 Protein smpB signature. 216591010449 Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330 216591010450 Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403 216591010451 HMMPfam hit to PF01145, SPFH domain / Band, score 6.4e-73 216591010452 HMMPfam hit to PF01957, Nodulation efficiency protein D (NfeD), score 1.4e-06 216591010453 2 probable transmembrane helices predicted for BCAL2073 by TMHMM2.0 at aa 17-39 and 54-76 216591010454 phosphoenolpyruvate synthase; Validated; Region: PRK06464 216591010455 Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326 216591010456 PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391 216591010457 PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 216591010458 HMMPfam hit to PF02896, PEP-utilising enzyme, TIM barrel doma, score 1.3e-59 216591010459 PS00742 PEP-utilizing enzymes signature 2. 216591010460 HMMPfam hit to PF00391, PEP-utilising enzyme, mobile domain, score 1.5e-40 216591010461 PS00370 PEP-utilizing enzymes phosphorylation site signature. 216591010462 HMMPfam hit to PF01326, Pyruvate phosphate dikinase, PEP/pyru, score 3.3e-141 216591010463 PEP synthetase regulatory protein; Provisional; Region: PRK05339 216591010464 HMMPfam hit to PF03618, Domain of unknown function (DUF299), score 4.4e-115 216591010465 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010466 rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566 216591010467 SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588 216591010468 HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 8.6e-42 216591010469 bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182 216591010470 RNA/DNA hybrid binding site [nucleotide binding]; other site 216591010471 active site 216591010472 HMMPfam hit to PF01351, Ribonuclease HII, score 1.8e-75 216591010473 lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025 216591010474 ipid-A-disaccharide synthase; Provisional; Region: PRK14089 216591010475 HMMPfam hit to PF02684, Lipid-A-disaccharide synthetase, score 3.7e-104 216591010476 UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289 216591010477 UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351 216591010478 active site 216591010479 PS00101 Hexapeptide-repeat containing-transferases signature. 216591010480 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 2.7 216591010481 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 8.8 216591010482 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 2.8 216591010483 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 28 216591010484 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 2.6 216591010485 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.018 216591010486 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 2.2 216591010487 FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288 216591010488 HMMPfam hit to PF07977, FabA-like domain, score 3.6e-59 216591010489 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892 216591010490 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613 216591010491 UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352 216591010492 trimer interface [polypeptide binding]; other site 216591010493 active site 216591010494 UDP-GlcNAc binding site [chemical binding]; other site 216591010495 lipid binding site [chemical binding]; lipid-binding site 216591010496 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 36 216591010497 PS00101 Hexapeptide-repeat containing-transferases signature. 216591010498 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1.1 216591010499 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.94 216591010500 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.3 216591010501 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.012 216591010502 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.011 216591010503 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.69 216591010504 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.39 216591010505 PS00101 Hexapeptide-repeat containing-transferases signature. 216591010506 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 3.9 216591010507 HMMPfam hit to PF04613, UDP-3-O-[3-hydroxymyristoyl] glucosamine N-a, score 4.6e-34 216591010508 periplasmic chaperone; Provisional; Region: PRK10780 216591010509 Outer membrane protein (OmpH-like); Region: OmpH; smart00935 216591010510 HMMPfam hit to PF03938, Outer membrane protein (OmpH-like), score 4e-56 216591010511 outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303 216591010512 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 216591010513 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 216591010514 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 216591010515 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 216591010516 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 216591010517 Surface antigen; Region: Bac_surface_Ag; pfam01103 216591010518 HMMPfam hit to PF01103, Surface antigen, score 4.7e-65 216591010519 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 3.1e-20 216591010520 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 1.5e-19 216591010521 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 1.6e-19 216591010522 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 2.4e-14 216591010523 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 5.2e-17 216591010524 zinc metallopeptidase RseP; Provisional; Region: PRK10779 216591010525 RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163 216591010526 active site 216591010527 PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989 216591010528 protein binding site [polypeptide binding]; other site 216591010529 RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163 216591010530 putative substrate binding region [chemical binding]; other site 216591010531 HMMPfam hit to PF02163, Peptidase family M50, score 6.1e-74 216591010532 4 probable transmembrane helices predicted for BCAL2084 by TMHMM2.0 at aa 7-29, 100-122, 382-404 and 428-447 216591010533 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 0.0059 216591010534 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447 216591010535 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670 216591010536 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436 216591010537 DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288 216591010538 HMMPfam hit to PF08436, 1-deoxy-D-xylulose 5-phosphate reduct, score 7.3e-62 216591010539 HMMPfam hit to PF02670, 1-deoxy-D-xylulose 5-phosphate reduct, score 3.5e-68 216591010540 CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575 216591010541 Cytidylyltransferase family; Region: CTP_transf_1; pfam01148 216591010542 HMMPfam hit to PF01148, Cytidylyltransferase family, score 5.2e-54 216591010543 PS01315 Phosphatidate cytidylyltransferase signature. 216591010544 7 probable transmembrane helices predicted for BCAL2086 by TMHMM2.0 at aa 7-41, 51-73, 80-97, 107-129, 134-156, 176-198 and 205-227 216591010545 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010546 Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020 216591010547 Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475 216591010548 catalytic residue [active] 216591010549 putative FPP diphosphate binding site; other site 216591010550 putative FPP binding hydrophobic cleft; other site 216591010551 dimer interface [polypeptide binding]; other site 216591010552 putative IPP diphosphate binding site; other site 216591010553 HMMPfam hit to PF01255, Putative undecaprenyl diphosphate syntha, score 1.3e-113 216591010554 PS01066 Undecaprenyl pyrophosphate synthetase family signature. 216591010555 ribosome recycling factor; Reviewed; Region: frr; PRK00083 216591010556 Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520 216591010557 hinge region; other site 216591010558 HMMPfam hit to PF01765, Ribosome recycling factor, score 9.8e-90 216591010559 UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254 216591010560 putative nucleotide binding site [chemical binding]; other site 216591010561 uridine monophosphate binding site [chemical binding]; other site 216591010562 homohexameric interface [polypeptide binding]; other site 216591010563 HMMPfam hit to PF00696, Amino acid kinase family, score 4.1e-64 216591010564 elongation factor Ts; Provisional; Region: tsf; PRK09377 216591010565 UBA/TS-N domain; Region: UBA; pfam00627 216591010566 Elongation factor TS; Region: EF_TS; pfam00889 216591010567 Elongation factor TS; Region: EF_TS; pfam00889 216591010568 HMMPfam hit to PF00889, Elongation factor TS, score 9.8e-86 216591010569 PS01127 Elongation factor Ts signature 2. 216591010570 HMMPfam hit to PF00627, UBA/TS-N domain, score 1e-09 216591010571 Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425 216591010572 rRNA interaction site [nucleotide binding]; other site 216591010573 S8 interaction site; other site 216591010574 putative laminin-1 binding site; other site 216591010575 HMMPfam hit to PF00318, Ribosomal protein S2, score 6.9e-97 216591010576 PS00962 Ribosomal protein S2 signature 1. 216591010577 Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086 216591010578 active site 216591010579 HMMPfam hit to PF00557, metallopeptidase family M24, score 1.2e-85 216591010580 PS00680 Methionine aminopeptidase subfamily 1 signature. 216591010581 PII uridylyl-transferase; Provisional; Region: PRK03059 216591010582 Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401 216591010583 metal binding triad; other site 216591010584 GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335 216591010585 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 216591010586 Zn2+ binding site [ion binding]; other site 216591010587 Mg2+ binding site [ion binding]; other site 216591010588 ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900 216591010589 C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899 216591010590 HMMPfam hit to PF01909, Nucleotidyltransferase domain, score 1.2e-10 216591010591 HMMPfam hit to PF08335, GlnD PII-uridylyltransferase, score 1.9e-104 216591010592 HMMPfam hit to PF01966, HD domain, score 3.2e-12 216591010593 HMMPfam hit to PF01842, ACT domain, score 0.0031 216591010594 HMMPfam hit to PF01842, ACT domain, score 0.00097 216591010595 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187 216591010596 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 216591010597 RNA binding surface [nucleotide binding]; other site 216591010598 Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130 216591010599 active site 216591010600 HMMPfam hit to PF01479, S4 domain, score 1.1e-10 216591010601 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 2.1e-07 216591010602 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 216591010603 active site 216591010604 catalytic residues [active] 216591010605 metal binding site [ion binding]; metal-binding site 216591010606 HMMPfam hit to PF01327, Polypeptide deformylase, score 9.7e-46 216591010607 NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114 216591010608 NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956 216591010609 nucleotide binding pocket [chemical binding]; other site 216591010610 K-X-D-G motif; other site 216591010611 catalytic site [active] 216591010612 NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120 216591010613 NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119 216591010614 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786 216591010615 Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027 216591010616 Dimer interface [polypeptide binding]; other site 216591010617 BRCT sequence motif; other site 216591010618 HMMPfam hit to PF00533, BRCA1 C Terminus (BRCT) domain, score 8.6e-20 216591010619 HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 0.00031 216591010620 HMMPfam hit to PF03119, NAD-dependent DNA ligase C4 zinc fing, score 1e-12 216591010621 HMMPfam hit to PF03120, NAD-dependent DNA ligase OB-fold doma, score 1.4e-50 216591010622 PS01056 NAD-dependent DNA ligase signature 2. 216591010623 HMMPfam hit to PF01653, NAD-dependent DNA ligase adenylation, score 2.6e-169 216591010624 ZipA, C-terminal domain (FtsZ-binding); Region: ZipA_C; smart00771 216591010625 1 probable transmembrane helix predicted for BCAL2097 by TMHMM2.0 at aa 4-26 216591010626 chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168 216591010627 ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278 216591010628 Walker A/P-loop; other site 216591010629 ATP binding site [chemical binding]; other site 216591010630 Q-loop/lid; other site 216591010631 SMC proteins Flexible Hinge Domain; Region: SMC_hinge; cl05797 216591010632 ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278 216591010633 Q-loop/lid; other site 216591010634 ABC transporter signature motif; other site 216591010635 Walker B; other site 216591010636 D-loop; other site 216591010637 H-loop/switch region; other site 216591010638 HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 2.3e-92 216591010639 HMMPfam hit to PF06470, SMC proteins Flexible Hinge Domain, score 2.3e-20 216591010640 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010641 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 216591010642 EamA-like transporter family; Region: EamA; pfam00892 216591010643 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.5e-09 216591010644 9 probable transmembrane helices predicted for BCAL2099 by TMHMM2.0 at aa 7-29, 33-55, 67-89, 93-115, 122-139, 154-171, 187-209, 214-236 and 248-267 216591010645 succinyldiaminopimelate transaminase; Provisional; Region: PRK09147 216591010646 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591010647 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591010648 homodimer interface [polypeptide binding]; other site 216591010649 catalytic residue [active] 216591010650 HMMPfam hit to PF00155, Aminotransferase class I and II, score 4.9e-38 216591010651 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830 216591010652 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350 216591010653 trimer interface [polypeptide binding]; other site 216591010654 active site 216591010655 substrate binding site [chemical binding]; other site 216591010656 CoA binding site [chemical binding]; other site 216591010657 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 30 216591010658 PS00101 Hexapeptide-repeat containing-transferases signature. 216591010659 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.81 216591010660 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 3.9 216591010661 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.93 216591010662 Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035 216591010663 ArsC family; Region: ArsC; pfam03960 216591010664 putative catalytic residues [active] 216591010665 HMMPfam hit to PF03960, ArsC family, score 6.7e-32 216591010666 succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009 216591010667 M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891 216591010668 metal binding site [ion binding]; metal-binding site 216591010669 dimer interface [polypeptide binding]; other site 216591010670 PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 216591010671 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 4.8e-52 216591010672 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 1.3e-37 216591010673 HemK family putative methylases; Region: hemK_fam; TIGR00536 216591010674 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591010675 S-adenosylmethionine binding site [chemical binding]; other site 216591010676 HMMPfam hit to PF05175, Methyltransferase small domain, score 1.5e-08 216591010677 HMMPfam hit to PF08242, Methyltransferase domain, score 0.0029 216591010678 PS00092 N-6 Adenine-specific DNA methylases signature. 216591010679 cardiolipin synthetase; Reviewed; Region: cls; PRK01642 216591010680 Putative catalytic domain, repeat 1, of Pseudomonas aeruginosa cardiolipin synthase and similar proteins; Region: PLDc_PaCLS_like_1; cd09155 216591010681 putative active site [active] 216591010682 catalytic site [active] 216591010683 Putative catalytic domain, repeat 2, of Pseudomonas aeruginosa cardiolipin synthase and similar proteins; Region: PLDc_PaCLS_like_2; cd09161 216591010684 putative active site [active] 216591010685 catalytic site [active] 216591010686 2 probable transmembrane helices predicted for BCAL2105 by TMHMM2.0 at aa 5-27 and 36-58 216591010687 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010688 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 3.3e-07 216591010689 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 2.4e-06 216591010690 Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340 216591010691 catalytic residues [active] 216591010692 dimer interface [polypeptide binding]; other site 216591010693 HMMPfam hit to PF00255, Glutathione peroxidase, score 2e-55 216591010694 PS00763 Glutathione peroxidases signature 2. 216591010695 PS00460 Glutathione peroxidases selenocysteine active site. 216591010696 putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636 216591010697 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 216591010698 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 216591010699 ABC transporter; Region: ABC_tran_2; pfam12848 216591010700 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 216591010701 HMMPfam hit to PF00005, ABC transporter, score 3.4e-49 216591010702 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010703 PS00211 ABC transporters family signature. 216591010704 HMMPfam hit to PF00005, ABC transporter, score 7.9e-41 216591010705 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010706 PS00211 ABC transporters family signature. 216591010707 Protein of unknown function (DUF2866); Region: DUF2866; pfam11065 216591010708 DNA repair protein RadA; Provisional; Region: PRK11823 216591010709 Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121 216591010710 Walker A motif/ATP binding site; other site 216591010711 ATP binding site [chemical binding]; other site 216591010712 Walker B motif; other site 216591010713 Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541 216591010714 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010715 alanine racemase; Reviewed; Region: alr; PRK00053 216591010716 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827 216591010717 active site 216591010718 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 216591010719 substrate binding site [chemical binding]; other site 216591010720 catalytic residues [active] 216591010721 dimer interface [polypeptide binding]; other site 216591010722 HMMPfam hit to PF00842, Alanine racemase, C-terminal domain, score 2.6e-63 216591010723 HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 3.3e-76 216591010724 PS00395 Alanine racemase pyridoxal-phosphate attachment site. 216591010725 lysophospholipid transporter LplT; Provisional; Region: PRK11195 216591010726 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591010727 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.3e-08 216591010728 10 probable transmembrane helices predicted for BCAL2111 by TMHMM2.0 at aa 13-30, 45-62, 83-105, 163-185, 223-245, 260-279, 286-305, 325-347, 372-391 and 395-414 216591010729 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169 216591010730 dimer interface [polypeptide binding]; other site 216591010731 substrate binding site [chemical binding]; other site 216591010732 ATP binding site [chemical binding]; other site 216591010733 HMMPfam hit to PF08543, Phosphomethylpyrimidine kinase, score 9.1e-142 216591010734 Domain of unknown function (DUF1853); Region: DUF1853; pfam08907 216591010735 Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030 216591010736 Fe-S cluster binding site [ion binding]; other site 216591010737 active site 216591010738 HMMPfam hit to PF03167, Uracil DNA glycosylase superfamily, score 3.6e-33 216591010739 ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575 216591010740 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591010741 HMMPfam hit to PF08445, FR47-like protein, score 0.00034 216591010742 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.2e-18 216591010743 tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725 216591010744 Glycoprotease family; Region: Peptidase_M22; pfam00814 216591010745 HMMPfam hit to PF00814, Glycoprotease family, score 5.2e-41 216591010746 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010747 Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; Region: ACBP; cl00221 216591010748 acyl-CoA binding pocket [chemical binding]; other site 216591010749 CoA binding site [chemical binding]; other site 216591010750 HMMPfam hit to PF00887, Acyl CoA binding protein, score 5.9e-41 216591010751 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 216591010752 DEAD-like helicases superfamily; Region: DEXDc; smart00487 216591010753 ATP binding site [chemical binding]; other site 216591010754 Mg++ binding site [ion binding]; other site 216591010755 motif III; other site 216591010756 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591010757 nucleotide binding region [chemical binding]; other site 216591010758 ATP-binding site [chemical binding]; other site 216591010759 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 4.4e-64 216591010760 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 216591010761 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 8.5e-34 216591010762 isocitrate lyase; Provisional; Region: PRK15063 216591010763 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 216591010764 tetramer interface [polypeptide binding]; other site 216591010765 active site 216591010766 Mg2+/Mn2+ binding site [ion binding]; other site 216591010767 HMMPfam hit to PF00463, Isocitrate lyase family, score 1.7e-243 216591010768 PS00161 Isocitrate lyase signature. 216591010769 PS00030 Eukaryotic putative RNA-binding region RNP-1 signature. 216591010770 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591010771 Ligand Binding Site [chemical binding]; other site 216591010772 HMMPfam hit to PF00582, Universal stress protein family, score 2.8e-18 216591010773 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591010774 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591010775 putative effector binding pocket; other site 216591010776 dimerization interface [polypeptide binding]; other site 216591010777 HMMPfam hit to PF03466, LysR substrate binding domain, score 1e-50 216591010778 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5e-15 216591010779 2-haloalkanoic acid dehalogenase, type II; Region: HAD_type_II; TIGR01428 216591010780 REG-2-like, HAD superfamily (subfamily IA) hydrolase; Region: DREG-2; TIGR02252 216591010781 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591010782 motif II; other site 216591010783 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.6e-19 216591010784 malate synthase A; Region: malate_syn_A; TIGR01344 216591010785 Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727 216591010786 active site 216591010787 HMMPfam hit to PF01274, Malate synthase, score 0 216591010788 PS00510 Malate synthase signature. 216591010789 Predicted helix-turn-helix motif with score 1613.000, SD 4.68 at aa 442-463, sequence HNLMEDAATAEISRSQVWQWIR 216591010790 GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661 216591010791 putative active site pocket [active] 216591010792 dimerization interface [polypeptide binding]; other site 216591010793 putative catalytic residue [active] 216591010794 HMMPfam hit to PF03674, Uncharacterised protein family (UPF0131), score 3.9e-05 216591010795 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 216591010796 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591010797 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591010798 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591010799 HMMPfam hit to PF02311, AraC-like ligand binding domain, score 4.3e-12 216591010800 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 0.00034 216591010801 Predicted helix-turn-helix motif with score 1610.000, SD 4.67 at aa 183-204, sequence ESLEHWASEVGASTRTISRLFK 216591010802 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 1.8e-05 216591010803 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591010804 Coenzyme A binding pocket [chemical binding]; other site 216591010805 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.4e-14 216591010806 glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406 216591010807 catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808 216591010808 active site 216591010809 HIGH motif; other site 216591010810 catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808 216591010811 active site 216591010812 KMSKS motif; other site 216591010813 HMMPfam hit to PF00749, tRNA synthetases class I (E and Q), cata, score 1.4e-137 216591010814 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591010815 hypothetical protein; Provisional; Region: PRK10279 216591010816 Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205 216591010817 nucleophile elbow; other site 216591010818 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010819 HMMPfam hit to PF01734, Patatin-like phospholipase, score 5.7e-47 216591010820 Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791 216591010821 NlpC/P60 family; Region: NLPC_P60; pfam00877 216591010822 HMMPfam hit to PF00877, NlpC/P60 family, score 5.2e-49 216591010823 1 probable transmembrane helix predicted for BCAL2128 by TMHMM2.0 at aa 13-30 216591010824 ABC-type uncharacterized transport system, duplicated ATPase component [General function prediction only]; Region: COG4172 216591010825 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591010826 Walker A/P-loop; other site 216591010827 ATP binding site [chemical binding]; other site 216591010828 Q-loop/lid; other site 216591010829 ABC transporter signature motif; other site 216591010830 Walker B; other site 216591010831 D-loop; other site 216591010832 H-loop/switch region; other site 216591010833 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 216591010834 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591010835 Walker A/P-loop; other site 216591010836 ATP binding site [chemical binding]; other site 216591010837 Q-loop/lid; other site 216591010838 ABC transporter signature motif; other site 216591010839 Walker B; other site 216591010840 D-loop; other site 216591010841 H-loop/switch region; other site 216591010842 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 216591010843 HMMPfam hit to PF00005, ABC transporter, score 4.4e-64 216591010844 PS00211 ABC transporters family signature. 216591010845 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010846 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 1.4e-05 216591010847 HMMPfam hit to PF00005, ABC transporter, score 5.5e-55 216591010848 PS00211 ABC transporters family signature. 216591010849 PS00017 ATP/GTP-binding site motif A (P-loop). 216591010850 ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239 216591010851 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591010852 dimer interface [polypeptide binding]; other site 216591010853 conserved gate region; other site 216591010854 putative PBP binding loops; other site 216591010855 ABC-ATPase subunit interface; other site 216591010856 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.4e-46 216591010857 4 probable transmembrane helices predicted for BCAL2130 by TMHMM2.0 at aa 34-56, 161-183, 204-226 and 321-343 216591010858 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591010859 ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174 216591010860 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591010861 dimer interface [polypeptide binding]; other site 216591010862 conserved gate region; other site 216591010863 putative PBP binding loops; other site 216591010864 ABC-ATPase subunit interface; other site 216591010865 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.3e-50 216591010866 6 probable transmembrane helices predicted for BCAL2131 by TMHMM2.0 at aa 9-31, 119-141, 153-175, 205-227, 264-286 and 314-336 216591010867 PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1. 216591010868 ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166 216591010869 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497 216591010870 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 1e-60 216591010871 PS01310 ATP1G1 / PLM / MAT8 family signature. 216591010872 2 probable transmembrane helices predicted for BCAL2133 by TMHMM2.0 at aa 13-35 and 55-77 216591010873 Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841 216591010874 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 6.1e-152 216591010875 10 probable transmembrane helices predicted for BCAL2134 by TMHMM2.0 at aa 7-29, 359-381, 429-451, 456-478, 550-569, 891-913, 920-939, 949-971, 990-1012 and 1027-1049 216591010876 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 216591010877 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591010878 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591010879 2 probable transmembrane helices predicted for BCAL2135 by TMHMM2.0 at aa 15-37 and 44-66 216591010880 HMMPfam hit to PF00529, HlyD family secretion protein, score 5.5e-07 216591010881 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591010882 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010883 HMMPfam hit to PF02321, Outer membrane efflux protein, score 9.2e-30 216591010884 HMMPfam hit to PF02321, Outer membrane efflux protein, score 4.9e-41 216591010885 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591010886 transcriptional regulatory protein YedW; Provisional; Region: PRK11517 216591010887 DNA binding site [nucleotide binding] 216591010888 Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862 216591010889 HMMPfam hit to PF00486, Transcriptional regulatory protein, C ter, score 7.8e-15 216591010890 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591010891 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591010892 dimerization interface [polypeptide binding]; other site 216591010893 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591010894 dimer interface [polypeptide binding]; other site 216591010895 phosphorylation site [posttranslational modification] 216591010896 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591010897 ATP binding site [chemical binding]; other site 216591010898 Mg2+ binding site [ion binding]; other site 216591010899 G-X-G motif; other site 216591010900 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.3e-29 216591010901 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.00055 216591010902 HMMPfam hit to PF00672, HAMP domain, score 3.8e-15 216591010903 2 probable transmembrane helices predicted for BCAL2138 by TMHMM2.0 at aa 21-43 and 161-183 216591010904 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591010905 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591010906 active site 216591010907 phosphorylation site [posttranslational modification] 216591010908 intermolecular recognition site; other site 216591010909 dimerization interface [polypeptide binding]; other site 216591010910 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591010911 DNA binding site [nucleotide binding] 216591010912 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.1e-24 216591010913 HMMPfam hit to PF00072, Response regulator receiver domain, score 4.6e-28 216591010914 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591010915 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010916 cytochrome o ubiquinol oxidase subunit IV; Region: CyoD; TIGR02847 216591010917 3 probable transmembrane helices predicted for BCAL2141 by TMHMM2.0 at aa 20-42, 47-69 and 79-101 216591010918 HMMPfam hit to PF03626, Prokaryotic Cytochrome C oxidase subunit IV, score 6.1e-36 216591010919 Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863 216591010920 Subunit I/III interface [polypeptide binding]; other site 216591010921 Subunit III/IV interface [polypeptide binding]; other site 216591010922 HMMPfam hit to PF00510, Cytochrome c oxidase subunit III, score 6.9e-05 216591010923 5 probable transmembrane helices predicted for BCAL2142 by TMHMM2.0 at aa 23-45, 65-87, 94-111, 134-156 and 177-199 216591010924 Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843 216591010925 Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662 216591010926 D-pathway; other site 216591010927 Putative ubiquinol binding site [chemical binding]; other site 216591010928 Low-spin heme (heme b) binding site [chemical binding]; other site 216591010929 Putative water exit pathway; other site 216591010930 Binuclear center (heme o3/CuB) [ion binding]; other site 216591010931 K-pathway; other site 216591010932 Putative proton exit pathway; other site 216591010933 15 probable transmembrane helices predicted for BCAL2143 by TMHMM2.0 at aa 15-37, 57-79, 104-126, 139-161, 190-212, 232-254, 279-301, 308-330, 345-367, 380-402, 417-439, 456-478, 493-515, 585-607 and 611-630 216591010934 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010935 HMMPfam hit to PF00115, Cytochrome C and Quinol oxidase polypeptide, score 1.2e-267 216591010936 PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 216591010937 cytochrome o ubiquinol oxidase subunit II; Region: CyoA; TIGR01433 216591010938 Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116 216591010939 COX Aromatic Rich Motif; Region: COX_ARM; pfam06481 216591010940 HMMPfam hit to PF06481, COX Aromatic Rich Motif, score 3.1e-13 216591010941 HMMPfam hit to PF00116, Cytochrome C oxidase subunit II, periplasmic, score 5.6e-05 216591010942 3 probable transmembrane helices predicted for BCAL2144 by TMHMM2.0 at aa 7-29, 44-66 and 85-107 216591010943 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591010944 NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846 216591010945 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 216591010946 14 probable transmembrane helices predicted for BCAL2145 by TMHMM2.0 at aa 4-26, 33-55, 80-102, 115-132, 137-156, 168-189, 204-226, 239-261, 271-293, 300-322, 327-349, 370-392, 402-424 and 445-465 216591010947 HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex I), score 2.6e-76 216591010948 aspartate kinase; Reviewed; Region: PRK06635 216591010949 AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261 216591010950 putative nucleotide binding site [chemical binding]; other site 216591010951 putative catalytic residues [active] 216591010952 putative Mg ion binding site [ion binding]; other site 216591010953 putative aspartate binding site [chemical binding]; other site 216591010954 ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913 216591010955 putative allosteric regulatory site; other site 216591010956 ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936 216591010957 HMMPfam hit to PF01842, ACT domain, score 1.4e-10 216591010958 HMMPfam hit to PF01842, ACT domain, score 2.5e-10 216591010959 HMMPfam hit to PF00696, Amino acid kinase family, score 1.9e-76 216591010960 PS00324 Aspartokinase signature. 216591010961 tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660 216591010962 N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992 216591010963 Ligand Binding Site [chemical binding]; other site 216591010964 TilS substrate binding domain; Region: TilS; pfam09179 216591010965 TilS substrate C-terminal domain; Region: TilS_C; pfam11734 216591010966 HMMPfam hit to PF01171, PP-loop family, score 3.6e-72 216591010967 acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724 216591010968 acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198 216591010969 HMMPfam hit to PF03255, Acetyl co-enzyme A carboxylase carboxyltrans, score 1.6e-90 216591010970 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 216591010971 endonuclease III; Region: ENDO3c; smart00478 216591010972 minor groove reading motif; other site 216591010973 helix-hairpin-helix signature motif; other site 216591010974 substrate binding pocket [chemical binding]; other site 216591010975 active site 216591010976 HMMPfam hit to PF00730, HhH-GPD superfamily base excision DNA repair, score 8.4e-11 216591010977 cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260 216591010978 catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672 216591010979 active site 216591010980 HIGH motif; other site 216591010981 catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672 216591010982 KMSKS motif; other site 216591010983 Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963 216591010984 tRNA binding surface [nucleotide binding]; other site 216591010985 anticodon binding site; other site 216591010986 HMMPfam hit to PF01406, tRNA synthetases class I (C) catalytic d, score 1.8e-177 216591010987 TPR repeat; Region: TPR_11; pfam13414 216591010988 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591010989 binding surface 216591010990 TPR motif; other site 216591010991 1 probable transmembrane helix predicted for BCAL2151 by TMHMM2.0 at aa 12-34 216591010992 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.8e-05 216591010993 HMMPfam hit to PF00160, Cyclophilin type peptidyl-prolyl cis-tr, score 1.4e-52 216591010994 PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 216591010995 cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920 216591010996 substrate binding site [chemical binding]; other site 216591010997 HMMPfam hit to PF00160, Cyclophilin type peptidyl-prolyl cis-tr, score 8.4e-51 216591010998 PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 216591010999 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 216591011000 Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398 216591011001 putative active site [active] 216591011002 putative metal binding site [ion binding]; other site 216591011003 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 3.3e-10 216591011004 serine O-acetyltransferase; Region: cysE; TIGR01172 216591011005 Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354 216591011006 trimer interface [polypeptide binding]; other site 216591011007 active site 216591011008 substrate binding site [chemical binding]; other site 216591011009 CoA binding site [chemical binding]; other site 216591011010 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 2.2 216591011011 PS00047 Histone H4 signature. 216591011012 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.0044 216591011013 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 4.6 216591011014 rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565 216591011015 SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307 216591011016 HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 1.1e-30 216591011017 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483 216591011018 IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639 216591011019 active site 216591011020 dimerization interface [polypeptide binding]; other site 216591011021 HMMPfam hit to PF00459, Inositol monophosphatase family, score 3.5e-87 216591011022 PS00629 Inositol monophosphatase family signature 1. 216591011023 PS00630 Inositol monophosphatase family signature 2. 216591011024 Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509 216591011025 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591011026 HMMPfam hit to PF03486, HI0933-like protein, score 0.0028 216591011027 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 7.2e-06 216591011028 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 0.00024 216591011029 EthD domain; Region: EthD; cl17553 216591011030 HMMPfam hit to PF07110, EthD protein, score 9.8e-23 216591011031 DNA mismatch repair protein MutS; Provisional; Region: PRK05399 216591011032 MutS domain I; Region: MutS_I; pfam01624 216591011033 MutS domain II; Region: MutS_II; pfam05188 216591011034 MutS domain III; Region: MutS_III; pfam05192 216591011035 ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284 216591011036 Walker A/P-loop; other site 216591011037 ATP binding site [chemical binding]; other site 216591011038 Q-loop/lid; other site 216591011039 ABC transporter signature motif; other site 216591011040 Walker B; other site 216591011041 D-loop; other site 216591011042 H-loop/switch region; other site 216591011043 HMMPfam hit to PF01624, MutS domain I, score 3.2e-73 216591011044 HMMPfam hit to PF05188, MutS domain II, score 7.3e-20 216591011045 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011046 HMMPfam hit to PF05192, MutS domain III, score 2.7e-62 216591011047 HMMPfam hit to PF05190, MutS family domain IV, score 9.8e-46 216591011048 HMMPfam hit to PF00488, MutS domain V, score 9.9e-158 216591011049 PS00017 ATP/GTP-binding site motif A (P-loop). 216591011050 PS00486 DNA mismatch repair proteins mutS family signature. 216591011051 FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047 216591011052 Uncharacterized conserved protein [Function unknown]; Region: COG2850 216591011053 HMMPfam hit to PF08007, Cupin superfamily protein, score 8.2e-112 216591011054 Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235 216591011055 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 1.4e-13 216591011056 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011057 Uncharacterized lipoprotein [Cell envelope biogenesis, outer membrane]; Region: NlpB; COG3317 216591011058 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011059 Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950 216591011060 dihydrodipicolinate synthase; Region: dapA; TIGR00674 216591011061 dimer interface [polypeptide binding]; other site 216591011062 active site 216591011063 catalytic residue [active] 216591011064 HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 1.7e-137 216591011065 PS00666 Dihydrodipicolinate synthetase signature 2. 216591011066 HMMPfam hit to PF08241, Methyltransferase domain, score 0.00075 216591011067 HMMPfam hit to PF08242, Methyltransferase domain, score 8.2e-07 216591011068 catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806 216591011069 active site 216591011070 HIGH motif; other site 216591011071 dimer interface [polypeptide binding]; other site 216591011072 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 216591011073 active site 216591011074 KMSKS motif; other site 216591011075 HMMPfam hit to PF00579, tRNA synthetases class I (W and Y), score 2.7e-72 216591011076 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591011077 Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158 216591011078 Peptidase family M50; Region: Peptidase_M50; pfam02163 216591011079 active site 216591011080 putative substrate binding region [chemical binding]; other site 216591011081 6 probable transmembrane helices predicted for BCAL2170 by TMHMM2.0 at aa 9-31, 56-78, 91-113, 128-150, 171-193 and 197-219 216591011082 HMMPfam hit to PF02163, Peptidase family M50, score 4.3e-27 216591011083 Telomere recombination; Region: Sua5_yciO_yrdC; cl00305 216591011084 HMMPfam hit to PF01300, yrdC domain, score 9.6e-56 216591011085 Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613 216591011086 Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438 216591011087 active site 216591011088 Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438 216591011089 HMMPfam hit to PF02811, PHP domain, score 5.8e-22 216591011090 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591011091 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591011092 Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303 216591011093 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 3e-12 216591011094 PS00120 Lipases, serine active site. 216591011095 Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657 216591011096 dinuclear metal binding motif [ion binding]; other site 216591011097 HMMPfam hit to PF04305, Protein of unknown function (DUF455), score 2e-95 216591011098 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663 216591011099 Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645 216591011100 trimer interface [polypeptide binding]; other site 216591011101 putative metal binding site [ion binding]; other site 216591011102 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 20 216591011103 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 43 216591011104 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1.7 216591011105 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.024 216591011106 PS00017 ATP/GTP-binding site motif A (P-loop). 216591011107 Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114 216591011108 Heat shock protein 33 (Hsp33): Cytosolic protein that acts as a molecular chaperone under oxidative conditions. In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498 216591011109 dimerization interface [polypeptide binding]; other site 216591011110 domain crossover interface; other site 216591011111 redox-dependent activation switch; other site 216591011112 HMMPfam hit to PF01430, Hsp33 protein, score 1.5e-74 216591011113 1 probable transmembrane helix predicted for BCAL2177 by TMHMM2.0 at aa 13-35 216591011114 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011115 cell division protein FtsB; Reviewed; Region: ftsB; PRK00888 216591011116 Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919 216591011117 HMMPfam hit to PF04977, Septum formation initiator, score 2.9e-24 216591011118 enolase; Provisional; Region: eno; PRK00077 216591011119 Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313 216591011120 dimer interface [polypeptide binding]; other site 216591011121 metal binding site [ion binding]; metal-binding site 216591011122 substrate binding pocket [chemical binding]; other site 216591011123 HMMPfam hit to PF00113, Enolase, C-terminal TIM barrel domain, score 2.6e-173 216591011124 PS00164 Enolase signature. 216591011125 HMMPfam hit to PF03952, Enolase, N-terminal domain, score 3.8e-64 216591011126 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198 216591011127 DAHP synthetase I family; Region: DAHP_synth_1; pfam00793 216591011128 HMMPfam hit to PF00793, DAHP synthetase I family, score 8.4e-105 216591011129 PS00017 ATP/GTP-binding site motif A (P-loop). 216591011130 PS00284 Serpins signature. 216591011131 CTP synthetase; Validated; Region: pyrG; PRK05380 216591011132 CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113 216591011133 Catalytic site [active] 216591011134 active site 216591011135 UTP binding site [chemical binding]; other site 216591011136 Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746 216591011137 active site 216591011138 putative oxyanion hole; other site 216591011139 catalytic triad [active] 216591011140 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.1e-66 216591011141 PS00442 Glutamine amidotransferases class-I active site. 216591011142 HMMPfam hit to PF06418, CTP synthase N-terminus, score 1.5e-209 216591011143 1 probable transmembrane helix predicted for BCAL2181 by TMHMM2.0 at aa 5-27 216591011144 Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208 216591011145 Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303 216591011146 PS00120 Lipases, serine active site. 216591011147 Domain of unknown function (DUF4131); Region: DUF4131; pfam13567 216591011148 DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361 216591011149 Competence protein; Region: Competence; pfam03772 216591011150 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 1.8e-13 216591011151 HMMPfam hit to PF03772, Competence protein, score 8.6e-52 216591011152 7 probable transmembrane helices predicted for BCAL2183 by TMHMM2.0 at aa 7-29, 33-55, 62-84, 273-295, 308-330, 350-372 and 377-399 216591011153 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011154 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011155 TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310 216591011156 active site 216591011157 HMMPfam hit to PF01026, TatD related DNase, score 7.8e-77 216591011158 PS01091 Uncharacterized protein family UPF0006 signature 3. 216591011159 lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211 216591011160 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 216591011161 Walker A/P-loop; other site 216591011162 ATP binding site [chemical binding]; other site 216591011163 Q-loop/lid; other site 216591011164 ABC transporter signature motif; other site 216591011165 Walker B; other site 216591011166 D-loop; other site 216591011167 H-loop/switch region; other site 216591011168 HMMPfam hit to PF00005, ABC transporter, score 4.1e-66 216591011169 PS00211 ABC transporters family signature. 216591011170 PS00017 ATP/GTP-binding site motif A (P-loop). 216591011171 lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212 216591011172 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 216591011173 FtsX-like permease family; Region: FtsX; pfam02687 216591011174 HMMPfam hit to PF02687, Predicted permease, score 1.9e-42 216591011175 4 probable transmembrane helices predicted for BCAL2186 by TMHMM2.0 at aa 24-46, 274-296, 329-351 and 384-406 216591011176 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011177 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4255 216591011178 ssDNA exonuclease RecJ; Provisional; Region: PRK11070 216591011179 DHH family; Region: DHH; pfam01368 216591011180 DHHA1 domain; Region: DHHA1; pfam02272 216591011181 HMMPfam hit to PF01368, DHH family, score 7e-53 216591011182 HMMPfam hit to PF02272, DHHA1 domain, score 2e-10 216591011183 peptide chain release factor 2; Validated; Region: prfB; PRK00578 216591011184 This domain is found in peptide chain release factors; Region: PCRF; smart00937 216591011185 RF-1 domain; Region: RF-1; pfam00472 216591011186 HMMPfam hit to PF03462, PCRF domain, score 1.7e-52 216591011187 HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 1.1e-72 216591011188 lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484 216591011189 LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322 216591011190 dimer interface [polypeptide binding]; other site 216591011191 putative anticodon binding site; other site 216591011192 Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775 216591011193 motif 1; other site 216591011194 active site 216591011195 motif 2; other site 216591011196 motif 3; other site 216591011197 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 5.4e-20 216591011198 HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 6.8e-127 216591011199 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591011200 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591011201 1 probable transmembrane helix predicted for BCAL2191 by TMHMM2.0 at aa 32-54 216591011202 HMMPfam hit to PF05433, Rickettsia 17 kDa surface antigen, score 4.3e-14 216591011203 Iron-sulphur cluster assembly; Region: Fe-S_assembly; pfam04384 216591011204 HMMPfam hit to PF04384, Protein of unknown function (DUF528), score 4.8e-41 216591011205 Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633 216591011206 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591011207 catalytic loop [active] 216591011208 iron binding site [ion binding]; other site 216591011209 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 1e-16 216591011210 PS00190 Cytochrome c family heme-binding site signature. 216591011211 PS00814 Adrenodoxin family, iron-sulfur binding region signature. 216591011212 chaperone protein HscA; Provisional; Region: hscA; PRK05183 216591011213 Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236 216591011214 nucleotide binding site [chemical binding]; other site 216591011215 putative NEF/HSP70 interaction site [polypeptide binding]; other site 216591011216 SBD interface [polypeptide binding]; other site 216591011217 HMMPfam hit to PF00012, Hsp70 protein, score 3.5e-222 216591011218 PS01036 Heat shock hsp70 proteins family signature 3. 216591011219 PS00329 Heat shock hsp70 proteins family signature 2. 216591011220 PS00297 Heat shock hsp70 proteins family signature 1. 216591011221 co-chaperone HscB; Provisional; Region: hscB; PRK03578 216591011222 DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257 216591011223 HSP70 interaction site [polypeptide binding]; other site 216591011224 HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743 216591011225 HMMPfam hit to PF07743, HSCB C-terminal oligomerisation domain, score 6.8e-23 216591011226 HMMPfam hit to PF00226, DnaJ domain, score 2.6e-06 216591011227 iron-sulfur cluster assembly protein IscA; Region: IscA; TIGR02011 216591011228 PS01152 Hypothetical hesB/yadR/yfhF family signature. 216591011229 HMMPfam hit to PF01521, Iron-sulphur cluster biosynthesis, score 1.9e-41 216591011230 NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822 216591011231 Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664 216591011232 trimerization site [polypeptide binding]; other site 216591011233 active site 216591011234 HMMPfam hit to PF01592, NifU-like N terminal domain, score 2.8e-78 216591011235 cysteine desulfurase; Provisional; Region: PRK14012 216591011236 cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402 216591011237 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591011238 catalytic residue [active] 216591011239 HMMPfam hit to PF00266, Aminotransferase class-V, score 1.9e-125 216591011240 HMMPfam hit to PF01212, Beta-eliminating lyase, score 2.5e-05 216591011241 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 216591011242 Predicted transcriptional regulator [Transcription]; Region: COG1959 216591011243 iron-sulfur cluster assembly transcription factor IscR; Region: IscR; TIGR02010 216591011244 HMMPfam hit to PF02082, Transcriptional regulator, score 1.7e-49 216591011245 Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394 216591011246 Low molecular weight phosphatase family; Region: LMWPc; cd00115 216591011247 active site 216591011248 HMMPfam hit to PF01451, Low molecular weight phosphotyrosine protein, score 1.3e-55 216591011249 1 probable transmembrane helix predicted for BCAL2201 by TMHMM2.0 at aa 5-27 216591011250 Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139 216591011251 Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589 216591011252 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 216591011253 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0012 216591011254 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591011255 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 216591011256 Cysteine-rich domain; Region: CCG; pfam02754 216591011257 Cysteine-rich domain; Region: CCG; pfam02754 216591011258 HMMPfam hit to PF02754, Cysteine-rich domain, score 4e-07 216591011259 HMMPfam hit to PF02754, Cysteine-rich domain, score 2.2e-14 216591011260 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 216591011261 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591011262 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591011263 Predicted helix-turn-helix motif with score 1773.000, SD 5.23 at aa 32-53, sequence VSLKELAQRTELHPSTAHRILN 216591011264 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 1.8e-29 216591011265 D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768 216591011266 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872 216591011267 HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase, score 1.6e-57 216591011268 Phasin protein; Region: Phasin_2; pfam09361 216591011269 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 216591011270 E3 interaction surface; other site 216591011271 lipoyl attachment site [posttranslational modification]; other site 216591011272 dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467 216591011273 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591011274 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591011275 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 216591011276 HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 2.8e-48 216591011277 HMMPfam hit to PF01134, Glucose inhibited division protein A, score 9.4e-05 216591011278 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 8.4e-65 216591011279 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 2.2e-17 216591011280 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 216591011281 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 7.3e-25 216591011282 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 216591011283 dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855 216591011284 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 216591011285 E3 interaction surface; other site 216591011286 lipoyl attachment site [posttranslational modification]; other site 216591011287 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 216591011288 E3 interaction surface; other site 216591011289 lipoyl attachment site [posttranslational modification]; other site 216591011290 e3 binding domain; Region: E3_binding; pfam02817 216591011291 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 216591011292 HMMPfam hit to PF00198, 2-oxoacid dehydrogenases acyltransferas, score 1.3e-124 216591011293 HMMPfam hit to PF02817, e3 binding domain, score 1.4e-18 216591011294 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 1.6e-25 216591011295 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 216591011296 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 3e-23 216591011297 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 216591011298 pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405 216591011299 Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017 216591011300 dimer interface [polypeptide binding]; other site 216591011301 TPP-binding site [chemical binding]; other site 216591011302 PAS domain S-box; Region: sensory_box; TIGR00229 216591011303 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591011304 putative active site [active] 216591011305 heme pocket [chemical binding]; other site 216591011306 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591011307 dimer interface [polypeptide binding]; other site 216591011308 phosphorylation site [posttranslational modification] 216591011309 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591011310 ATP binding site [chemical binding]; other site 216591011311 Mg2+ binding site [ion binding]; other site 216591011312 G-X-G motif; other site 216591011313 2 probable transmembrane helices predicted for BCAL2210 by TMHMM2.0 at aa 35-57 and 283-302 216591011314 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011315 HMMPfam hit to PF00989, PAS fold, score 3.4e-15 216591011316 HMMPfam hit to PF08448, PAS fold, score 4e-10 216591011317 HMMPfam hit to PF08447, PAS fold, score 1.9e-07 216591011318 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.1e-10 216591011319 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.2e-31 216591011320 Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566 216591011321 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591011322 active site 216591011323 phosphorylation site [posttranslational modification] 216591011324 intermolecular recognition site; other site 216591011325 dimerization interface [polypeptide binding]; other site 216591011326 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591011327 DNA binding residues [nucleotide binding] 216591011328 dimerization interface [polypeptide binding]; other site 216591011329 HMMPfam hit to PF00072, Response regulator receiver domain, score 7.7e-35 216591011330 HMMPfam hit to PF08281, Sigma-70, region, score 1e-05 216591011331 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 7e-22 216591011332 PS00622 Bacterial regulatory proteins, luxR family signature. 216591011333 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14189 216591011334 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763 216591011335 NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080 216591011336 homodimer interface [polypeptide binding]; other site 216591011337 NADP binding site [chemical binding]; other site 216591011338 substrate binding site [chemical binding]; other site 216591011339 HMMPfam hit to PF00763, Tetrahydrofolate dehydrogenase/cyclohyd, score 1.7e-57 216591011340 HMMPfam hit to PF02882, Tetrahydrofolate dehydrogenase/cyclohyd, score 2e-111 216591011341 PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 216591011342 Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339 216591011343 Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456 216591011344 active site 216591011345 Zn binding site [ion binding]; other site 216591011346 HMMPfam hit to PF01432, Peptidase family M3, score 1.6e-183 216591011347 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591011348 DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586 216591011349 active site 216591011350 DNA polymerase IV; Validated; Region: PRK02406 216591011351 DNA binding site [nucleotide binding] 216591011352 HMMPfam hit to PF00817, impB/mucB/samB family, score 6.3e-99 216591011353 Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794 216591011354 aspartate racemase; Region: asp_race; TIGR00035 216591011355 HMMPfam hit to PF01177, Asp/Glu/Hydantoin racemase, score 4.5e-44 216591011356 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591011357 Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007 216591011358 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591011359 putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005 216591011360 Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050 216591011361 IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817 216591011362 HMMPfam hit to PF03050, Transposase IS66 family, score 1.1e-99 216591011363 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591011364 IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717 216591011365 HMMPfam hit to PF05717, IS66 Orf2 like protein, score 3.2e-62 216591011366 Transposase; Region: HTH_Tnp_1; pfam01527 216591011367 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591011368 HMMPfam hit to PF01527, Transposase, score 1.2e-10 216591011369 Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086 216591011370 putative catalytic site [active] 216591011371 putative phosphate binding site [ion binding]; other site 216591011372 active site 216591011373 metal binding site A [ion binding]; metal-binding site 216591011374 DNA binding site [nucleotide binding] 216591011375 putative AP binding site [nucleotide binding]; other site 216591011376 putative metal binding site B [ion binding]; other site 216591011377 HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 3.7e-47 216591011378 PS00728 AP endonucleases family 1 signature 3. 216591011379 Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505 216591011380 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 216591011381 HMMPfam hit to PF00326, Prolyl oligopeptidase family, score 5.5e-69 216591011382 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011383 HMMPfam hit to PF02897, Prolyl oligopeptidase, N-terminal beta, score 3.7e-07 216591011384 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591011385 Response regulator receiver domain; Region: Response_reg; pfam00072 216591011386 active site 216591011387 phosphorylation site [posttranslational modification] 216591011388 intermolecular recognition site; other site 216591011389 dimerization interface [polypeptide binding]; other site 216591011390 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591011391 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 216591011392 Walker A motif; other site 216591011393 ATP binding site [chemical binding]; other site 216591011394 Walker B motif; other site 216591011395 arginine finger; other site 216591011396 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591011397 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 2.1e-11 216591011398 Predicted helix-turn-helix motif with score 1720.000, SD 5.05 at aa 481-502, sequence GRKVEAAERLGIGRNTITRKIQ 216591011399 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591011400 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3.4e-143 216591011401 HMMPfam hit to PF07728, ATPase family associated with various, score 0.0002 216591011402 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591011403 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591011404 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.4e-32 216591011405 Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852 216591011406 PAS domain; Region: PAS; smart00091 216591011407 putative active site [active] 216591011408 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591011409 dimer interface [polypeptide binding]; other site 216591011410 phosphorylation site [posttranslational modification] 216591011411 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591011412 ATP binding site [chemical binding]; other site 216591011413 Mg2+ binding site [ion binding]; other site 216591011414 G-X-G motif; other site 216591011415 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2.3e-27 216591011416 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 9.8e-16 216591011417 glutamine synthetase; Provisional; Region: glnA; PRK09469 216591011418 Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951 216591011419 Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120 216591011420 PS00182 Glutamine synthetase class-I adenylation site. 216591011421 HMMPfam hit to PF00120, Glutamine synthetase, catalytic domain, score 2.3e-171 216591011422 PS00181 Glutamine synthetase putative ATP-binding region signature. 216591011423 HMMPfam hit to PF03951, Glutamine synthetase, beta-Grasp domain, score 6.8e-47 216591011424 PS00180 Glutamine synthetase signature 1. 216591011425 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125 216591011426 active site residue [active] 216591011427 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; Region: CinA; COG1058 216591011428 Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885 216591011429 putative MPT binding site; other site 216591011430 HMMPfam hit to PF00994, Probable molybdopterin binding domain, score 1.7e-30 216591011431 Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264 216591011432 6 probable transmembrane helices predicted for BCAL2227 by TMHMM2.0 at aa 21-43, 78-100, 128-150, 155-177, 198-220 and 230-252 216591011433 Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000 216591011434 Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116 216591011435 4 probable transmembrane helices predicted for BCAL2228 by TMHMM2.0 at aa 40-59, 80-102, 127-149 and 190-212 216591011436 PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866 216591011437 40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276 216591011438 HrpA-like helicases [DNA replication, recombination, and repair]; Region: HrpA; COG1643 216591011439 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 216591011440 ATP binding site [chemical binding]; other site 216591011441 putative Mg++ binding site [ion binding]; other site 216591011442 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591011443 nucleotide binding region [chemical binding]; other site 216591011444 ATP-binding site [chemical binding]; other site 216591011445 Helicase associated domain (HA2); Region: HA2; pfam04408 216591011446 Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717 216591011447 Domain of unknown function (DUF3418); Region: DUF3418; pfam11898 216591011448 Domain of unknown function (DUF3418); Region: DUF3418; pfam11898 216591011449 HMMPfam hit to PF07717, Domain of unknown function (DUF1605), score 1.3e-20 216591011450 HMMPfam hit to PF04408, Helicase associated domain (HA2), score 4.7e-26 216591011451 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 9.3e-12 216591011452 PS00017 ATP/GTP-binding site motif A (P-loop). 216591011453 N-acetylglutamate synthase; Validated; Region: PRK05279 216591011454 AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237 216591011455 putative feedback inhibition sensing region; other site 216591011456 putative nucleotide binding site [chemical binding]; other site 216591011457 putative substrate binding site [chemical binding]; other site 216591011458 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591011459 Coenzyme A binding pocket [chemical binding]; other site 216591011460 HMMPfam hit to PF00696, Amino acid kinase family, score 5.5e-14 216591011461 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.6e-12 216591011462 oxidative damage protection protein; Provisional; Region: PRK05408 216591011463 HMMPfam hit to PF04362, Bacterial Fe(2+) trafficking, score 1.3e-57 216591011464 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591011465 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591011466 putative substrate translocation pore; other site 216591011467 HMMPfam hit to PF00083, Sugar (and other) transporter, score 5.9e-07 216591011468 12 probable transmembrane helices predicted for BCAL2233 by TMHMM2.0 at aa 23-45, 60-82, 95-117, 127-149, 161-183, 193-215, 246-268, 283-305, 312-334, 338-360, 372-394 and 404-426 216591011469 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011470 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.2e-10 216591011471 PS00024 Hemopexin domain signature. 216591011472 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591011473 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591011474 HMMPfam hit to PF02515, CoA-transferase family III, score 4.1e-67 216591011475 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591011476 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591011477 active site 216591011478 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011479 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 6.2e-39 216591011480 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 0.00029 216591011481 PS00073 Acyl-CoA dehydrogenases signature 2. 216591011482 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 4.4e-17 216591011483 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 216591011484 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591011485 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591011486 dimerization interface [polypeptide binding]; other site 216591011487 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.7e-19 216591011488 Predicted helix-turn-helix motif with score 1247.000, SD 3.43 at aa 16-37, sequence LHFGRAAKRLFISQPALSFDIR 216591011489 PS00044 Bacterial regulatory proteins, lysR family signature. 216591011490 HMMPfam hit to PF03466, LysR substrate binding domain, score 7.9e-50 216591011491 putative aminotransferase; Validated; Region: PRK07480 216591011492 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591011493 inhibitor-cofactor binding pocket; inhibition site 216591011494 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591011495 catalytic residue [active] 216591011496 HMMPfam hit to PF00202, Aminotransferase class-III, score 6.7e-98 216591011497 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591011498 Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174 216591011499 Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120 216591011500 HMMPfam hit to PF00120, Glutamine synthetase, catalytic domain, score 4.9e-119 216591011501 Peptidase C26; Region: Peptidase_C26; pfam07722 216591011502 Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745 216591011503 catalytic triad [active] 216591011504 HMMPfam hit to PF07722, Peptidase C26, score 3.3e-104 216591011505 N-formylglutamate amidohydrolase; Region: FGase; cl01522 216591011506 HMMPfam hit to PF05013, N-formylglutamate amidohydrolase, score 1.6e-90 216591011507 N-formimino-L-glutamate deiminase; Validated; Region: PRK09229 216591011508 Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_E; cd01313 216591011509 active site 216591011510 HMMPfam hit to PF01979, Amidohydrolase family, score 4.1e-20 216591011511 imidazolonepropionase; Validated; Region: PRK09356 216591011512 Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296 216591011513 active site 216591011514 HMMPfam hit to PF01979, Amidohydrolase family, score 3.3e-08 216591011515 HMMPfam hit to PF07969, Amidohydrolase family, score 2.4e-07 216591011516 HutD; Region: HutD; pfam05962 216591011517 HMMPfam hit to PF05962, Bacterial protein of unknown function (DUF88, score 2.2e-53 216591011518 urocanate hydratase; Provisional; Region: PRK05414 216591011519 HMMPfam hit to PF01175, Urocanase, score 0 216591011520 PS01233 Urocanase active site. 216591011521 histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018 216591011522 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591011523 DNA-binding site [nucleotide binding]; DNA binding site 216591011524 UTRA domain; Region: UTRA; pfam07702 216591011525 HMMPfam hit to PF07702, UTRA domain, score 3e-38 216591011526 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.3e-22 216591011527 Predicted helix-turn-helix motif with score 1354.000, SD 3.80 at aa 29-50, sequence PSENELAREFKVARMTVNRALR 216591011528 Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332 216591011529 active sites [active] 216591011530 tetramer interface [polypeptide binding]; other site 216591011531 HMMPfam hit to PF00221, Phenylalanine and histidine ammonia-lyase, score 2.2e-232 216591011532 PS00488 Phenylalanine and histidine ammonia-lyases signature. 216591011533 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591011534 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591011535 substrate binding pocket [chemical binding]; other site 216591011536 membrane-bound complex binding site; other site 216591011537 hinge residues; other site 216591011538 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 7.1e-50 216591011539 Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091 216591011540 4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648 216591011541 HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase superfami, score 1e-12 216591011542 Predicted alpha/beta hydrolase [General function prediction only]; Region: COG4757 216591011543 putative choline sulfate-utilization transcription factor; Region: chol_sulf_TF; TIGR03418 216591011544 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591011545 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591011546 dimerization interface [polypeptide binding]; other site 216591011547 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.8e-16 216591011548 Predicted helix-turn-helix motif with score 1860.000, SD 5.52 at aa 24-45, sequence MSITLAAQDLCVTQSAVSRQIH 216591011549 PS00044 Bacterial regulatory proteins, lysR family signature. 216591011550 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.7e-27 216591011551 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591011552 putative substrate translocation pore; other site 216591011553 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591011554 12 probable transmembrane helices predicted for BCAL2251 by TMHMM2.0 at aa 12-34, 49-71, 78-100, 104-126, 139-161, 166-188, 220-242, 257-279, 284-306, 311-333, 340-362 and 372-394 216591011555 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7e-43 216591011556 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011557 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011558 Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415 216591011559 DNA photolyase; Region: DNA_photolyase; pfam00875 216591011560 HMMPfam hit to PF03441, FAD binding domain of DNA photolyase, score 6.5e-121 216591011561 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011562 PS00691 DNA photolyases class 1 signature 2. 216591011563 HMMPfam hit to PF00875, DNA photolyase, score 2.1e-42 216591011564 Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_4; cd07822 216591011565 putative hydrophobic ligand binding site [chemical binding]; other site 216591011566 SnoaL-like domain; Region: SnoaL_4; pfam13577 216591011567 short chain dehydrogenase; Provisional; Region: PRK07890 216591011568 classical (c) SDRs; Region: SDR_c; cd05233 216591011569 NAD(P) binding site [chemical binding]; other site 216591011570 active site 216591011571 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.8e-15 216591011572 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591011573 PS00215 Mitochondrial energy transfer proteins signature. 216591011574 sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039 216591011575 This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713 216591011576 Active Sites [active] 216591011577 HMMPfam hit to PF01507, Phosphoadenosine phosphosulfate reductase, score 2.4e-135 216591011578 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Provisional; Region: PRK05506 216591011579 CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166 216591011580 CysD dimerization site [polypeptide binding]; other site 216591011581 G1 box; other site 216591011582 putative GEF interaction site [polypeptide binding]; other site 216591011583 GTP/Mg2+ binding site [chemical binding]; other site 216591011584 Switch I region; other site 216591011585 G2 box; other site 216591011586 G3 box; other site 216591011587 Switch II region; other site 216591011588 G4 box; other site 216591011589 G5 box; other site 216591011590 CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695 216591011591 TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095 216591011592 Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027 216591011593 ligand-binding site [chemical binding]; other site 216591011594 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 2.2e-70 216591011595 PS00017 ATP/GTP-binding site motif A (P-loop). 216591011596 PS00301 GTP-binding elongation factors signature. 216591011597 HMMPfam hit to PF03144, Elongation factor Tu domain, score 5.4e-08 216591011598 HMMPfam hit to PF01583, Adenylylsulphate kinase, score 3.1e-109 216591011599 PS00017 ATP/GTP-binding site motif A (P-loop). 216591011600 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591011601 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591011602 DNA binding residues [nucleotide binding] 216591011603 dimerization interface [polypeptide binding]; other site 216591011604 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 0.00032 216591011605 Predicted helix-turn-helix motif with score 1457.000, SD 4.15 at aa 371-392, sequence LTLDEAAAATGITKNTARAHLR 216591011606 D-galactonate transporter; Region: 2A0114; TIGR00893 216591011607 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591011608 putative substrate translocation pore; other site 216591011609 12 probable transmembrane helices predicted for BCAL2262 by TMHMM2.0 at aa 21-38, 53-75, 88-110, 115-137, 150-172, 182-204, 251-273, 288-310, 319-336, 341-363, 372-394 and 404-426 216591011610 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.9e-48 216591011611 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011612 Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282 216591011613 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 216591011614 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591011615 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591011616 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.4e-09 216591011617 PS00041 Bacterial regulatory proteins, araC family signature. 216591011618 Predicted helix-turn-helix motif with score 1223.000, SD 3.35 at aa 264-285, sequence PSVDDVARELHVSARTLKRKLA 216591011619 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011620 Fatty acid desaturase; Region: FA_desaturase; pfam00487 216591011621 4 probable transmembrane helices predicted for BCAL2265 by TMHMM2.0 at aa 20-40, 45-64, 79-96 and 196-218 216591011622 haloacid dehalogenase-like hydrolase; Region: HAD; cl17202 216591011623 Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560 216591011624 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.0002 216591011625 Tellurium resistance protein; Region: Tellurium_res; pfam10138 216591011626 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310 216591011627 Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974 216591011628 putative metal binding site [ion binding]; other site 216591011629 HMMPfam hit to PF02342, Bacterial stress protein, score 1e-33 216591011630 PS00761 Signal peptidases I signature 3. 216591011631 hypothetical protein; Provisional; Region: PRK14013 216591011632 HMMPfam hit to PF04332, Protein of unknown function (DUF475), score 3.3e-103 216591011633 8 probable transmembrane helices predicted for BCAL2269 by TMHMM2.0 at aa 7-29, 64-86, 99-121, 146-168, 175-194, 231-253, 274-291 and 295-317 216591011634 Toxic anion resistance protein (TelA); Region: TelA; pfam05816 216591011635 HMMPfam hit to PF05816, Toxic anion resistance protein (TelA), score 2.4e-27 216591011636 Uncharacterized conserved protein [Function unknown]; Region: COG4104 216591011637 HMMPfam hit to PF05488, PAAR motif, score 2.9e-08 216591011638 HMMPfam hit to PF05488, PAAR motif, score 4.4e-06 216591011639 Uncharacterized conserved protein [Function unknown]; Region: COG4104 216591011640 HMMPfam hit to PF05488, PAAR motif, score 2.9e-08 216591011641 HMMPfam hit to PF05488, PAAR motif, score 4.4e-06 216591011642 2 probable transmembrane helices predicted for BCAL2276 by TMHMM2.0 at aa 12-34 and 49-71 216591011643 Protein of unknown function (DUF3274); Region: DUF3274; pfam11678 216591011644 PS00092 N-6 Adenine-specific DNA methylases signature. 216591011645 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011646 conserved hypothetical protein (pseudogene);CDS is disrupted by an IS element insertion after codon 908. May not affect protein function. Similar to Burkholderia pseudomallei hypothetical protein UniProt:Q63L00 (EMBL:BX571966) (925 aa) fasta scores: E()=4.6e-190, 54.693% id in 927 aa 216591011647 Transposase, Mutator family; Region: Transposase_mut; pfam00872 216591011648 MULE transposase domain; Region: MULE; pfam10551 216591011649 HMMPfam hit to PF00872, Transposase, Mutator family, score 2.8e-204 216591011650 PS01007 Transposases, Mutator family, signature. 216591011651 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 2.3e-21 216591011652 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591011653 HMMPfam hit to PF01810, LysE type translocator, score 1.3e-25 216591011654 6 probable transmembrane helices predicted for BCAL2280 by TMHMM2.0 at aa 6-28, 41-63, 78-100, 113-135, 150-172 and 185-204 216591011655 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 216591011656 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591011657 N-terminal plug; other site 216591011658 ligand-binding site [chemical binding]; other site 216591011659 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011660 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 8.1e-21 216591011661 HMMPfam hit to PF00593, TonB dependent receptor, score 1.4e-18 216591011662 PS01156 TonB-dependent receptor proteins signature 2. 216591011663 Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480 216591011664 probable sodium:solute symporter, VC_2705 subfamily; Region: Na_symport_lg; TIGR03648 216591011665 14 probable transmembrane helices predicted for BCAL2282 by TMHMM2.0 at aa 7-24, 34-56, 77-99, 104-126, 146-168, 178-200, 213-235, 366-388, 400-422, 493-515, 536-554, 564-586, 593-615 and 630-652 216591011666 HMMPfam hit to PF00474, Sodium:solute symporter family, score 3.2e-12 216591011667 Domain of unknown function (DUF4212); Region: DUF4212; pfam13937 216591011668 2 probable transmembrane helices predicted for BCAL2283 by TMHMM2.0 at aa 34-56 and 71-93 216591011669 acetyl-CoA synthetase; Provisional; Region: PRK00174 216591011670 Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966 216591011671 active site 216591011672 CoA binding site [chemical binding]; other site 216591011673 acyl-activating enzyme (AAE) consensus motif; other site 216591011674 AMP binding site [chemical binding]; other site 216591011675 acetate binding site [chemical binding]; other site 216591011676 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.7e-135 216591011677 PS00455 Putative AMP-binding domain signature. 216591011678 EamA-like transporter family; Region: EamA; pfam00892 216591011679 Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950 216591011680 EamA-like transporter family; Region: EamA; pfam00892 216591011681 10 probable transmembrane helices predicted for BCAL2285 by TMHMM2.0 at aa 5-27, 31-50, 63-85, 90-112, 119-137, 152-174, 187-209, 219-238, 245-267 and 272-294 216591011682 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.1e-20 216591011683 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.6e-19 216591011684 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011685 hypothetical protein; Provisional; Region: PRK05208 216591011686 HMMPfam hit to PF03350, Uncharacterized protein family, UPF0114, score 3.2e-55 216591011687 3 probable transmembrane helices predicted for BCAL2286 by TMHMM2.0 at aa 26-48, 68-90 and 147-169 216591011688 Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681 216591011689 Fumarase C-terminus; Region: Fumerase_C; pfam05683 216591011690 HMMPfam hit to PF05681, Fumarate hydratase (Fumerase), score 2.6e-155 216591011691 HMMPfam hit to PF05683, Fumarase C-terminus, score 2.7e-119 216591011692 Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193 216591011693 Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907 216591011694 heme binding site [chemical binding]; other site 216591011695 ferroxidase pore; other site 216591011696 ferroxidase diiron center [ion binding]; other site 216591011697 PS00549 Bacterioferritin signature. 216591011698 HMMPfam hit to PF00210, Ferritin-like domain, score 2.2e-48 216591011699 glutamate racemase; Provisional; Region: PRK00865 216591011700 HMMPfam hit to PF01177, Asp/Glu/Hydantoin racemase, score 5.4e-83 216591011701 PS00923 Aspartate and glutamate racemases signature 1. 216591011702 Bacterioferritin-associated ferredoxin [Inorganic ion transport and metabolism]; Region: Bfd; COG2906 216591011703 HMMPfam hit to PF04324, BFD-like [2Fe-2S] binding domain, score 1.7e-14 216591011704 Gram-negative bacterial tonB protein; Region: TonB; pfam03544 216591011705 Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810 216591011706 1 probable transmembrane helix predicted for BCAL2291 by TMHMM2.0 at aa 21-43 216591011707 Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811 216591011708 3 probable transmembrane helices predicted for BCAL2292 by TMHMM2.0 at aa 15-37, 131-153 and 178-200 216591011709 HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 2.2e-41 216591011710 Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848 216591011711 Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472 216591011712 HMMPfam hit to PF02472, Biopolymer transport protein ExbD/TolR, score 1.4e-21 216591011713 1 probable transmembrane helix predicted for BCAL2293 by TMHMM2.0 at aa 15-37 216591011714 LysR family transcriptional regulator; Provisional; Region: PRK14997 216591011715 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591011716 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473 216591011717 putative effector binding pocket; other site 216591011718 putative dimerization interface [polypeptide binding]; other site 216591011719 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.8e-44 216591011720 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.3e-15 216591011721 Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 21-42, sequence GGFSAAERVLGISKSRLSRRLT 216591011722 Pirin-related protein [General function prediction only]; Region: COG1741 216591011723 Pirin; Region: Pirin; pfam02678 216591011724 Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726 216591011725 HMMPfam hit to PF02678, Pirin, score 6.7e-53 216591011726 HMMPfam hit to PF05726, Pirin C-terminal cupin domain, score 2.8e-43 216591011727 DUF1857, an uncharacterized ligand-binding domain of the SRPBCC domain superfamily; Region: SRPBCC_DUF1857; cd08863 216591011728 putative hydrophobic ligand binding site [chemical binding]; other site 216591011729 Hemin uptake protein hemP; Region: hemP; pfam10636 216591011730 Polyferredoxin [Energy production and conversion]; Region: NapH; COG0348 216591011731 4Fe-4S binding domain; Region: Fer4_5; pfam12801 216591011732 9 probable transmembrane helices predicted for BCAL2298 by TMHMM2.0 at aa 25-47, 62-84, 113-135, 139-161, 269-291, 339-361, 374-396, 411-428 and 441-463 216591011733 Iron permease FTR1 family; Region: FTR1; cl00475 216591011734 HMMPfam hit to PF03239, Iron permease FTR1 family, score 4.5e-13 216591011735 7 probable transmembrane helices predicted for BCAL2299 by TMHMM2.0 at aa 4-26, 39-61, 71-93, 116-138, 153-175, 182-199 and 242-264 216591011736 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011737 Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473 216591011738 PS00430 TonB-dependent receptor proteins signature 1. 216591011739 Fe2+ transport protein; Region: Iron_transport; pfam10634 216591011740 excinuclease ABC subunit B; Provisional; Region: PRK05298 216591011741 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 216591011742 ATP binding site [chemical binding]; other site 216591011743 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591011744 nucleotide binding region [chemical binding]; other site 216591011745 ATP-binding site [chemical binding]; other site 216591011746 Ultra-violet resistance protein B; Region: UvrB; pfam12344 216591011747 UvrB/uvrC motif; Region: UVR; pfam02151 216591011748 HMMPfam hit to PF02151, UvrB/uvrC motif, score 2.4e-09 216591011749 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 5.9e-19 216591011750 PS00017 ATP/GTP-binding site motif A (P-loop). 216591011751 aromatic amino acid aminotransferase; Provisional; Region: PRK09257 216591011752 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591011753 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591011754 homodimer interface [polypeptide binding]; other site 216591011755 catalytic residue [active] 216591011756 HMMPfam hit to PF00155, Aminotransferase class I and II, score 2.2e-118 216591011757 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 216591011758 3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK13394 216591011759 classical (c) SDRs; Region: SDR_c; cd05233 216591011760 NAD(P) binding site [chemical binding]; other site 216591011761 active site 216591011762 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.9e-30 216591011763 PS00061 Short-chain dehydrogenases/reductases family signature. 216591011764 PS00017 ATP/GTP-binding site motif A (P-loop). 216591011765 voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293 216591011766 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591011767 active site 216591011768 catalytic tetrad [active] 216591011769 HMMPfam hit to PF00248, Aldo/keto reductase family, score 1.4e-74 216591011770 Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961 216591011771 HMMPfam hit to PF04378, Protein of unknown function (DUF519), score 1.2e-98 216591011772 Protein of unknown function (DUF3563); Region: DUF3563; pfam12086 216591011773 Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044 216591011774 Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108 216591011775 DNA binding residues [nucleotide binding] 216591011776 dimer interface [polypeptide binding]; other site 216591011777 copper binding site [ion binding]; other site 216591011778 HMMPfam hit to PF00376, MerR family regulatory protein, score 1.2e-12 216591011779 PS00552 Bacterial regulatory proteins, merR family signature. 216591011780 Predicted helix-turn-helix motif with score 1297.000, SD 3.60 at aa 1-22, sequence MNIGDASRESGVSAKMIRYYEQ 216591011781 Transposase; Region: HTH_Tnp_1; pfam01527 216591011782 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591011783 C-terminal region is highly similar to Burkholderia cepacia insertion element IS407 hypothetical 20.5 kDa protein SWALL:YI71_BURCE (SWALL:P24577) (183 aa) fasta scores: E(): 1.8e-71, 98.9% id in 183 aa. Full length CDS is highly similar to the C-terminal region of Burkholderia mallei TnpB SWALL:Q8GQT8 (EMBL:AF285636) (277 aa) fasta scores: E(): 5.4e-101, 98.41% id in 253 aa; CDS lacks appropriate translational start site. It is likely that this CDS encodes the C-terminal region of a larger protein encompassing the upstream CDS. A translational frameshift possibly occurs after residue 86 of the upstream overlapping CDS 216591011784 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591011785 Protein of unknown function (DUF2863); Region: DUF2863; pfam11062 216591011786 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591011787 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736 216591011788 active site 216591011789 phosphorylation site [posttranslational modification] 216591011790 dimerization interface [polypeptide binding]; other site 216591011791 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591011792 DNA binding residues [nucleotide binding] 216591011793 HMMPfam hit to PF00072, Response regulator receiver domain, score 0.0015 216591011794 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 6.3e-15 216591011795 Predicted helix-turn-helix motif with score 1512.000, SD 4.34 at aa 173-194, sequence STNKMIARTLGISEGTVKIHLA 216591011796 Predicted membrane protein [Function unknown]; Region: COG3235 216591011797 6 probable transmembrane helices predicted for BCAL2315 by TMHMM2.0 at aa 7-29, 44-62, 75-97, 107-125, 146-168 and 183-205 216591011798 Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866 216591011799 Peptidase M14-like domain of ATP/GTP binding proteins and cytosolic carboxypeptidases; uncharacterized bacterial subgroup; Region: M14_Nna1_like_1; cd06234 216591011800 putative active site [active] 216591011801 Zn binding site [ion binding]; other site 216591011802 HMMPfam hit to PF00246, Zinc carboxypeptidase, score 1.5e-56 216591011803 hypothetical protein; Validated; Region: PRK02101 216591011804 HMMPfam hit to PF03883, Protein of unknown function (DUF328), score 1.3e-144 216591011805 PIN domain; Region: PIN_3; pfam13470 216591011806 methionine aminotransferase; Validated; Region: PRK09082 216591011807 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591011808 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591011809 homodimer interface [polypeptide binding]; other site 216591011810 catalytic residue [active] 216591011811 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.1e-61 216591011812 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0012 216591011813 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591011814 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591011815 Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570 216591011816 C-terminal domain interface [polypeptide binding]; other site 216591011817 GSH binding site (G-site) [chemical binding]; other site 216591011818 dimer interface [polypeptide binding]; other site 216591011819 C-terminal, alpha helical domain of an unknown subfamily 9 of Glutathione S-transferases; Region: GST_C_9; cd10424 216591011820 putative N-terminal domain interface [polypeptide binding]; other site 216591011821 putative dimer interface [polypeptide binding]; other site 216591011822 putative substrate binding pocket (H-site) [chemical binding]; other site 216591011823 enoyl-CoA hydratase; Provisional; Region: PRK07511 216591011824 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591011825 substrate binding site [chemical binding]; other site 216591011826 oxyanion hole (OAH) forming residues; other site 216591011827 trimer interface [polypeptide binding]; other site 216591011828 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 5.2e-47 216591011829 PS00166 Enoyl-CoA hydratase/isomerase signature. 216591011830 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011831 GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972 216591011832 GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048 216591011833 C-terminal domain interface [polypeptide binding]; other site 216591011834 GSH binding site (G-site) [chemical binding]; other site 216591011835 dimer interface [polypeptide binding]; other site 216591011836 C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291 216591011837 N-terminal domain interface [polypeptide binding]; other site 216591011838 putative dimer interface [polypeptide binding]; other site 216591011839 active site 216591011840 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 9.6e-12 216591011841 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 3e-09 216591011842 NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their...; Region: NodN; cd03450 216591011843 putative active site [active] 216591011844 putative catalytic site [active] 216591011845 HMMPfam hit to PF01575, MaoC like domain, score 7.1e-28 216591011846 YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function. YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase. Other enzymes with this fold include the peroxisomal...; Region: YdeM; cd03454 216591011847 putative active site [active] 216591011848 putative catalytic site [active] 216591011849 HMMPfam hit to PF01575, MaoC like domain, score 2.3e-11 216591011850 pimeloyl-CoA dehydrogenase, small subunit; Region: pimD_small; TIGR03203 216591011851 Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771 216591011852 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 216591011853 active site 216591011854 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 8.5e-17 216591011855 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 0.0019 216591011856 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 2.3e-06 216591011857 pimeloyl-CoA dehydrogenase, large subunit; Region: pimC_large; TIGR03204 216591011858 Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26; Region: ACAD_fadE6_17_26; cd01152 216591011859 FAD binding site [chemical binding]; other site 216591011860 substrate binding site [chemical binding]; other site 216591011861 catalytic base [active] 216591011862 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 1.1e-23 216591011863 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 7.4e-27 216591011864 HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal doma, score 3e-05 216591011865 Protein of unknown function (DUF1178); Region: DUF1178; pfam06676 216591011866 HMMPfam hit to PF06676, Protein of unknown function (DUF1178), score 1.4e-63 216591011867 ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424 216591011868 dimer interface [polypeptide binding]; other site 216591011869 ADP-ribose binding site [chemical binding]; other site 216591011870 active site 216591011871 nudix motif; other site 216591011872 metal binding site [ion binding]; metal-binding site 216591011873 HMMPfam hit to PF00293, NUDIX domain, score 4.6e-19 216591011874 PS00893 mutT domain signature. 216591011875 Protein of unknown function (DUF2818); Region: DUF2818; pfam10993 216591011876 3 probable transmembrane helices predicted for BCAL2330 by TMHMM2.0 at aa 4-26, 39-58 and 73-95 216591011877 NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777 216591011878 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 216591011879 14 probable transmembrane helices predicted for BCAL2331 by TMHMM2.0 at aa 4-23, 35-54, 69-91, 104-121, 125-147, 160-182, 202-224, 237-259, 269-291, 298-317, 332-354, 374-396, 411-433 and 457-479 216591011880 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011881 HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex I), score 2.3e-69 216591011882 NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846 216591011883 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 216591011884 14 probable transmembrane helices predicted for BCAL2332 by TMHMM2.0 at aa 4-26, 33-55, 86-108, 115-133, 137-159, 166-188, 203-221, 241-263, 273-295, 302-324, 329-351, 372-394, 404-426 and 447-469 216591011885 HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex I), score 5.1e-102 216591011886 NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590 216591011887 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662 216591011888 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 216591011889 16 probable transmembrane helices predicted for BCAL2333 by TMHMM2.0 at aa 10-32, 39-61, 81-103, 116-135, 140-162, 175-197, 212-234, 255-277, 287-309, 316-335, 340-362, 382-404, 424-446, 493-515, 558-580 and 659-681 216591011890 HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex, score 1.8e-103 216591011891 HMMPfam hit to PF00662, NADH-Ubiquinone oxidoreductase (complex, score 3.6e-28 216591011892 NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715 216591011893 HMMPfam hit to PF00420, NADH-ubiquinone/plastoquinone oxidoreduct, score 1.6e-39 216591011894 3 probable transmembrane helices predicted for BCAL2334 by TMHMM2.0 at aa 5-24, 29-51 and 61-83 216591011895 NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638 216591011896 NADH dehydrogenase subunit J; Provisional; Region: PRK06433 216591011897 5 probable transmembrane helices predicted for BCAL2335 by TMHMM2.0 at aa 4-23, 30-49, 53-75, 88-110 and 145-167 216591011898 HMMPfam hit to PF00499, NADH-ubiquinone/plastoquinone oxidoreduct, score 1.1e-39 216591011899 NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971 216591011900 4Fe-4S binding domain; Region: Fer4; cl02805 216591011901 4Fe-4S binding domain; Region: Fer4; pfam00037 216591011902 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 5.9e-07 216591011903 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591011904 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 2e-05 216591011905 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591011906 NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076 216591011907 8 probable transmembrane helices predicted for BCAL2337 by TMHMM2.0 at aa 23-45, 89-111, 126-148, 168-190, 205-224, 255-277, 287-309 and 330-352 216591011908 HMMPfam hit to PF00146, NADH dehydrogenase, score 8.8e-151 216591011909 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011910 PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 216591011911 NADH dehydrogenase subunit G; Validated; Region: PRK09129 216591011912 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591011913 catalytic loop [active] 216591011914 iron binding site [ion binding]; other site 216591011915 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588 216591011916 MopB_NDH-1_NuoG2: The second domain of the NuoG subunit of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1), found in beta- and gammaproteobacteria. The NDH-1 is the first energy-transducting complex in the respiratory chain and functions as...; Region: MopB_NDH-1_NuoG2; cd02772 216591011917 HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 7.7e-33 216591011918 PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 216591011919 PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 216591011920 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 4.7e-10 216591011921 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894 216591011922 SLBB domain; Region: SLBB; pfam10531 216591011923 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928 216591011924 PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 216591011925 HMMPfam hit to PF01512, Respiratory-chain NADH dehydrogenase, score 3.9e-138 216591011926 NADH dehydrogenase subunit E; Validated; Region: PRK07539 216591011927 TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064 216591011928 putative dimer interface [polypeptide binding]; other site 216591011929 [2Fe-2S] cluster binding site [ion binding]; other site 216591011930 HMMPfam hit to PF01257, Respiratory-chain NADH dehydrogenase, score 1.7e-58 216591011931 NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649 216591011932 NADH dehydrogenase subunit D; Validated; Region: PRK06075 216591011933 HMMPfam hit to PF00346, Respiratory-chain NADH dehydrogenase,, score 6.5e-156 216591011934 PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 216591011935 NADH dehydrogenase subunit C; Provisional; Region: PRK06074 216591011936 NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961 216591011937 HMMPfam hit to PF00329, Respiratory-chain NADH dehydrogenase,, score 7.4e-43 216591011938 NADH dehydrogenase subunit B; Validated; Region: PRK06411 216591011939 HMMPfam hit to PF01058, NADH ubiquinone oxidoreductase, 20 Kd sub, score 1.2e-62 216591011940 PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 216591011941 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011942 NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602 216591011943 HMMPfam hit to PF00507, NADH-ubiquinone/plastoquinone oxidoreduct, score 1.6e-46 216591011944 3 probable transmembrane helices predicted for BCAL2344 by TMHMM2.0 at aa 4-26, 61-83 and 88-110 216591011945 Preprotein translocase SecG subunit; Region: SecG; pfam03840 216591011946 HMMPfam hit to PF03840, Preprotein translocase SecG subunit, score 6.7e-29 216591011947 2 probable transmembrane helices predicted for BCAL2345 by TMHMM2.0 at aa 7-26 and 54-76 216591011948 triosephosphate isomerase; Provisional; Region: PRK14567 216591011949 Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311 216591011950 substrate binding site [chemical binding]; other site 216591011951 dimer interface [polypeptide binding]; other site 216591011952 catalytic triad [active] 216591011953 HMMPfam hit to PF00121, Triosephosphate isomerase, score 4.4e-126 216591011954 PS00171 Triosephosphate isomerase active site. 216591011955 putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824 216591011956 PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276 216591011957 NAD(P) binding site [chemical binding]; other site 216591011958 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.9e-35 216591011959 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 8.9e-13 216591011960 polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824 216591011961 Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363 216591011962 RNase E interface [polypeptide binding]; other site 216591011963 trimer interface [polypeptide binding]; other site 216591011964 Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726 216591011965 Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364 216591011966 RNase E interface [polypeptide binding]; other site 216591011967 trimer interface [polypeptide binding]; other site 216591011968 active site 216591011969 Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393 216591011970 putative nucleic acid binding region [nucleotide binding]; other site 216591011971 G-X-X-G motif; other site 216591011972 S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472 216591011973 RNA binding site [nucleotide binding]; other site 216591011974 domain interface; other site 216591011975 HMMPfam hit to PF00575, S1 RNA binding domain, score 1.3e-21 216591011976 HMMPfam hit to PF00013, KH domain, score 5.1e-18 216591011977 HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 6.8e-19 216591011978 HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 2.1e-52 216591011979 HMMPfam hit to PF03726, Polyribonucleotide nucleotidyltransferase,, score 4.7e-21 216591011980 HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 8.8e-15 216591011981 HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 5.7e-35 216591011982 Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353 216591011983 16S/18S rRNA binding site [nucleotide binding]; other site 216591011984 S13e-L30e interaction site [polypeptide binding]; other site 216591011985 25S rRNA binding site [nucleotide binding]; other site 216591011986 HMMPfam hit to PF00312, Ribosomal protein S15, score 6.2e-39 216591011987 PS00362 Ribosomal protein S15 signature. 216591011988 Periplasmic binding protein; Region: Peripla_BP_6; pfam13458 216591011989 Periplasmic solute-binding domain of active transport proteins; Region: PBP1_SBP_like_3; cd06329 216591011990 putative ligand binding site [chemical binding]; other site 216591011991 PS00211 ABC transporters family signature. 216591011992 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591011993 Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883 216591011994 active site clefts [active] 216591011995 zinc binding site [ion binding]; other site 216591011996 dimer interface [polypeptide binding]; other site 216591011997 HMMPfam hit to PF00484, Carbonic anhydrase, score 5.5e-29 216591011998 PS00704 Prokaryotic-type carbonic anhydrases signature 1. 216591011999 PS00705 Prokaryotic-type carbonic anhydrases signature 2. 216591012000 Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792 216591012001 Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659 216591012002 Sulfate transporter family; Region: Sulfate_transp; pfam00916 216591012003 Sulphate Transporter and Anti-Sigma factor antagonist domain found in the C-terminal region of sulphate transporters as well as in bacterial and archaeal proteins involved in the regulation of sigma factors; Region: STAS; cl00604 216591012004 10 probable transmembrane helices predicted for BCAL2353 by TMHMM2.0 at aa 15-34, 41-63, 78-97, 109-131, 151-173, 194-216, 252-274, 295-314, 329-360 and 381-403 216591012005 HMMPfam hit to PF00916, Sulfate transporter family, score 2e-27 216591012006 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012007 2-isopropylmalate synthase; Validated; Region: PRK00915 216591012008 2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940 216591012009 active site 216591012010 catalytic residues [active] 216591012011 metal binding site [ion binding]; metal-binding site 216591012012 LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917 216591012013 HMMPfam hit to PF08502, LeuA allosteric (dimerisation) domain, score 2.5e-52 216591012014 HMMPfam hit to PF00682, HMGL-like, score 3e-129 216591012015 PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 216591012016 PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 216591012017 Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183 216591012018 CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066 216591012019 6 probable transmembrane helices predicted for BCAL2355 by TMHMM2.0 at aa 48-70, 138-155, 168-187, 202-224, 231-248 and 253-272 216591012020 HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 1e-20 216591012021 PS00379 CDP-alcohol phosphatidyltransferases signature. 216591012022 phosphatidylserine decarboxylase; Provisional; Region: PRK05305 216591012023 HMMPfam hit to PF02666, Phosphatidylserine decarboxylase, score 3.4e-40 216591012024 1 probable transmembrane helix predicted for BCAL2356 by TMHMM2.0 at aa 15-46 216591012025 ketol-acid reductoisomerase; Provisional; Region: PRK05479 216591012026 Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991 216591012027 Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450 216591012028 HMMPfam hit to PF01450, Acetohydroxy acid isomeroreductase, catalyti, score 3e-85 216591012029 HMMPfam hit to PF07991, Acetohydroxy acid isomeroreductase, catalyti, score 3.2e-107 216591012030 acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895 216591012031 N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878 216591012032 putative valine binding site [chemical binding]; other site 216591012033 dimer interface [polypeptide binding]; other site 216591012034 Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369 216591012035 HMMPfam hit to PF01842, ACT domain, score 2.6e-16 216591012036 PS00430 TonB-dependent receptor proteins signature 1. 216591012037 acetolactate synthase 3 catalytic subunit; Validated; Region: PRK06965 216591012038 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 216591012039 PYR/PP interface [polypeptide binding]; other site 216591012040 dimer interface [polypeptide binding]; other site 216591012041 TPP binding site [chemical binding]; other site 216591012042 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591012043 Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015 216591012044 TPP-binding site [chemical binding]; other site 216591012045 dimer interface [polypeptide binding]; other site 216591012046 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 7e-78 216591012047 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 4.6e-61 216591012048 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 3.7e-93 216591012049 PS00044 Bacterial regulatory proteins, lysR family signature. 216591012050 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591012051 RNA polymerase factor sigma-70; Validated; Region: PRK09047 216591012052 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591012053 DNA binding residues [nucleotide binding] 216591012054 HMMPfam hit to PF08281, Sigma-70, region, score 6.6e-16 216591012055 HMMPfam hit to PF04545, Sigma-70, region, score 9.4e-12 216591012056 Protein of unknown function (DUF3619); Region: DUF3619; pfam12279 216591012057 1 probable transmembrane helix predicted for BCAL2361 by TMHMM2.0 at aa 81-100 216591012058 Protein of unknown function (DUF3106); Region: DUF3106; pfam11304 216591012059 RDD family; Region: RDD; pfam06271 216591012060 HMMPfam hit to PF06271, RDD family, score 8.2e-27 216591012061 3 probable transmembrane helices predicted for BCAL2363 by TMHMM2.0 at aa 22-44, 51-73 and 119-141 216591012062 Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398 216591012063 putative active site [active] 216591012064 putative metal binding site [ion binding]; other site 216591012065 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 5.2e-07 216591012066 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591012067 This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_2; cd03814 216591012068 HMMPfam hit to PF00534, Glycosyl transferases group, score 2.4e-16 216591012069 Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818 216591012070 HMMPfam hit to PF01219, Prokaryotic diacylglycerol kinase, score 1.6e-33 216591012071 2 probable transmembrane helices predicted for BCAL2366 by TMHMM2.0 at aa 108-130 and 150-172 216591012072 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012073 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591012074 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591012075 Bacterial transcriptional repressor; Region: TetR; pfam13972 216591012076 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 4e-13 216591012077 Predicted helix-turn-helix motif with score 1665.000, SD 4.86 at aa 29-50, sequence VTTTTIAEEMEISPGNLYYHFR 216591012078 Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695 216591012079 HMMPfam hit to PF03641, Possible lysine decarboxylase, score 6.3e-60 216591012080 glucose-1-dehydrogenase; Provisional; Region: PRK06947 216591012081 classical (c) SDRs; Region: SDR_c; cd05233 216591012082 NAD(P) binding site [chemical binding]; other site 216591012083 active site 216591012084 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.3e-26 216591012085 PS00061 Short-chain dehydrogenases/reductases family signature. 216591012086 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807 216591012087 Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364 216591012088 13 probable transmembrane helices predicted for BCAL2370 by TMHMM2.0 at aa 56-78, 140-157, 169-188, 198-215, 228-250, 254-273, 280-302, 338-360, 369-391, 395-412, 425-447, 467-489 and 501-523 216591012089 Bacterial protein of unknown function (DUF924); Region: DUF924; pfam06041 216591012090 HMMPfam hit to PF06041, Bacterial protein of unknown function (DUF92, score 5.7e-82 216591012091 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872 216591012092 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863 216591012093 HMMPfam hit to PF07973, Threonyl and Alanyl tRNA synthetase second a, score 7.8e-14 216591012094 Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454 216591012095 apolar tunnel; other site 216591012096 heme binding site [chemical binding]; other site 216591012097 dimerization interface [polypeptide binding]; other site 216591012098 HMMPfam hit to PF01152, Bacterial-like globin, score 2.6e-63 216591012099 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127 216591012100 HMMPfam hit to PF02687, Predicted permease, score 8.6e-20 216591012101 10 probable transmembrane helices predicted for BCAL2374 by TMHMM2.0 at aa 47-69, 297-319, 340-362, 390-412, 432-454, 458-480, 508-530, 745-767, 798-820 and 835-857 216591012102 HMMPfam hit to PF02687, Predicted permease, score 2.7e-09 216591012103 PS00030 Eukaryotic putative RNA-binding region RNP-1 signature. 216591012104 Domain of unknown function (DUF4126); Region: DUF4126; pfam13548 216591012105 4 probable transmembrane helices predicted for BCAL2375 by TMHMM2.0 at aa 33-55, 70-92, 113-135 and 174-196 216591012106 multidrug efflux system protein; Provisional; Region: PRK11431 216591012107 4 probable transmembrane helices predicted for BCAL2376 by TMHMM2.0 at aa 2-19, 29-48, 55-77 and 82-104 216591012108 HMMPfam hit to PF00893, Small Multidrug Resistance protein, score 4.3e-35 216591012109 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591012110 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591012111 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591012112 HMMPfam hit to PF01548, Transposase, score 2.9e-12 216591012113 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591012114 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012115 Putative hemolysin [General function prediction only]; Region: Hlx; COG3042 216591012116 Domain of unknown function (DUF333); Region: DUF333; pfam03891 216591012117 HMMPfam hit to PF03891, Domain of unknown function (DUF333), score 3.7e-13 216591012118 DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529 216591012119 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591012120 active site 216591012121 phosphorylation site [posttranslational modification] 216591012122 intermolecular recognition site; other site 216591012123 dimerization interface [polypeptide binding]; other site 216591012124 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591012125 DNA binding site [nucleotide binding] 216591012126 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 7.6e-22 216591012127 HMMPfam hit to PF00072, Response regulator receiver domain, score 1e-37 216591012128 Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205 216591012129 Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702 216591012130 USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987 216591012131 Ligand Binding Site [chemical binding]; other site 216591012132 Domain of unknown function (DUF4118); Region: DUF4118; pfam13493 216591012133 GAF domain; Region: GAF_3; pfam13492 216591012134 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591012135 dimer interface [polypeptide binding]; other site 216591012136 phosphorylation site [posttranslational modification] 216591012137 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591012138 ATP binding site [chemical binding]; other site 216591012139 Mg2+ binding site [ion binding]; other site 216591012140 G-X-G motif; other site 216591012141 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3.1e-29 216591012142 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.9e-18 216591012143 4 probable transmembrane helices predicted for BCAL2380 by TMHMM2.0 at aa 410-429, 434-453, 457-479 and 486-508 216591012144 HMMPfam hit to PF00582, Universal stress protein family, score 2.4e-13 216591012145 HMMPfam hit to PF02702, Osmosensitive K+ channel His kinase sensor, score 2.5e-151 216591012146 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012147 potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315 216591012148 HMMPfam hit to PF02669, K+-transporting ATPase, c chain, score 8.1e-82 216591012149 1 probable transmembrane helix predicted for BCAL2381 by TMHMM2.0 at aa 7-29 216591012150 potassium-transporting ATPase subunit B; Provisional; Region: PRK01122 216591012151 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 216591012152 7 probable transmembrane helices predicted for BCAL2382 by TMHMM2.0 at aa 35-57, 62-84, 223-245, 260-282, 589-611, 626-648 and 667-689 216591012153 PS00018 EF-hand calcium-binding domain. 216591012154 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 4.1e-33 216591012155 PS00154 E1-E2 ATPases phosphorylation site. 216591012156 HMMPfam hit to PF00122, E1-E2 ATPase, score 1e-55 216591012157 potassium-transporting ATPase subunit A; Provisional; Region: PRK05482 216591012158 HMMPfam hit to PF03814, Potassium-transporting ATPase A subunit, score 0 216591012159 10 probable transmembrane helices predicted for BCAL2383 by TMHMM2.0 at aa 10-29, 65-84, 133-155, 176-198, 285-307, 312-329, 412-434, 455-477, 522-544 and 565-587 216591012160 PS00107 Protein kinases ATP-binding region signature. 216591012161 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012162 quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754 216591012163 Quinone oxidoreductase (QOR); Region: QOR2; cd05286 216591012164 NADP binding site [chemical binding]; other site 216591012165 dimer interface [polypeptide binding]; other site 216591012166 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.6e-39 216591012167 PS01162 Quinone oxidoreductase / zeta-crystallin signature. 216591012168 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 2.1e-22 216591012169 methylglyoxal synthase; Validated; Region: mgsA; PRK05234 216591012170 substrate binding site [chemical binding]; other site 216591012171 HMMPfam hit to PF02142, MGS-like domain, score 4e-24 216591012172 PS01335 Methylglyoxal synthase active site. 216591012173 short chain dehydrogenase; Provisional; Region: PRK08339 216591012174 putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR; Region: BKR_like_SDR_like; cd05344 216591012175 putative NAD(P) binding site [chemical binding]; other site 216591012176 putative active site [active] 216591012177 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.3e-15 216591012178 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012179 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 216591012180 active site 216591012181 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 1.1e-06 216591012182 hypothetical protein; Validated; Region: PRK00110 216591012183 HMMPfam hit to PF01709, Domain of unknown function DUF28, score 2.5e-152 216591012184 phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885 216591012185 Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844 216591012186 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071 216591012187 Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843 216591012188 HMMPfam hit to PF02844, Phosphoribosylglycinamide synthetase, N doma, score 1.1e-55 216591012189 HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase, ATP-gr, score 6.5e-120 216591012190 HMMPfam hit to PF02843, Phosphoribosylglycinamide synthetase, C doma, score 5e-49 216591012191 coproporphyrinogen III oxidase; Provisional; Region: PRK05330 216591012192 Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218 216591012193 HMMPfam hit to PF01218, Coproporphyrinogen III oxidase, score 4.4e-172 216591012194 PS01021 Coproporphyrinogen III oxidase signature. 216591012195 Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165 216591012196 nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071 216591012197 active site 216591012198 (T/H)XGH motif; other site 216591012199 HMMPfam hit to PF01467, Cytidylyltransferase, score 4.3e-36 216591012200 iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090 216591012201 HMMPfam hit to PF02410, Domain of unknown function DUF143, score 9.8e-34 216591012202 rRNA large subunit methyltransferase; Provisional; Region: PRK00103 216591012203 HMMPfam hit to PF02590, Uncharacterized ACR, COG1576, score 3.3e-80 216591012204 Maf-like protein; Region: Maf; pfam02545 216591012205 Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555 216591012206 active site 216591012207 dimer interface [polypeptide binding]; other site 216591012208 HMMPfam hit to PF02545, Maf-like protein, score 1.3e-45 216591012209 ribonuclease G; Provisional; Region: PRK11712 216591012210 S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453 216591012211 homodimer interface [polypeptide binding]; other site 216591012212 oligonucleotide binding site [chemical binding]; other site 216591012213 HMMPfam hit to PF00575, S1 RNA binding domain, score 7.9e-08 216591012214 Protein with unknown function (DUF469); Region: DUF469; pfam04320 216591012215 HMMPfam hit to PF04320, Protein with unknown function (DUF469), score 9.4e-24 216591012216 1 probable transmembrane helix predicted for BCAL2397 by TMHMM2.0 at aa 13-35 216591012217 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012218 PRC-barrel domain; Region: PRC; pfam05239 216591012219 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012220 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591012221 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591012222 putative substrate translocation pore; other site 216591012223 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.6e-30 216591012224 12 probable transmembrane helices predicted for BCAL2399 by TMHMM2.0 at aa 20-37, 47-69, 81-103, 107-129, 142-164, 168-185, 220-242, 252-274, 287-309, 319-338, 345-367 and 372-394 216591012225 5 probable transmembrane helices predicted for BCAL2400 by TMHMM2.0 at aa 30-52, 59-76, 86-103, 110-132 and 152-174 216591012226 PS00099 Thiolases active site. 216591012227 Domain of unknown function (DUF3315); Region: DUF3315; pfam11776 216591012228 1 probable transmembrane helix predicted for BCAL2401 by TMHMM2.0 at aa 21-38 216591012229 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 216591012230 UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511 216591012231 putative metal binding site; other site 216591012232 HMMPfam hit to PF00535, Glycosyl transferase family, score 1.5e-16 216591012233 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591012234 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859 216591012235 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 216591012236 putative active site [active] 216591012237 HMMPfam hit to PF01075, Glycosyltransferase family, score 2.4e-09 216591012238 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591012239 This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811 216591012240 putative ADP-binding pocket [chemical binding]; other site 216591012241 HMMPfam hit to PF00534, Glycosyl transferases group, score 1.4e-35 216591012242 9 probable transmembrane helices predicted for BCAL2405 by TMHMM2.0 at aa 15-37, 48-70, 85-102, 109-128, 143-165, 172-194, 209-231, 340-359 and 386-405 216591012243 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012244 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 216591012245 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859 216591012246 putative active site [active] 216591012247 HMMPfam hit to PF01075, Glycosyltransferase family, score 1.1e-08 216591012248 Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439 216591012249 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 216591012250 HMMPfam hit to PF00534, Glycosyl transferases group, score 3.3e-06 216591012251 lipid A export permease/ATP-binding protein MsbA; Region: MsbA_lipidA; TIGR02203 216591012252 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 216591012253 ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251 216591012254 Walker A/P-loop; other site 216591012255 ATP binding site [chemical binding]; other site 216591012256 Q-loop/lid; other site 216591012257 ABC transporter signature motif; other site 216591012258 Walker B; other site 216591012259 D-loop; other site 216591012260 H-loop/switch region; other site 216591012261 HMMPfam hit to PF00005, ABC transporter, score 3.8e-68 216591012262 PS00211 ABC transporters family signature. 216591012263 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012264 6 probable transmembrane helices predicted for BCAL2408 by TMHMM2.0 at aa 33-55, 70-92, 135-157, 172-194, 259-281 and 291-313 216591012265 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 7.4e-43 216591012266 DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673 216591012267 Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433 216591012268 putative active site [active] 216591012269 putative PHP Thumb interface [polypeptide binding]; other site 216591012270 DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485 216591012271 generic binding surface II; other site 216591012272 generic binding surface I; other site 216591012273 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 3.4e-09 216591012274 HMMPfam hit to PF07733, Bacterial DNA polymerase III alpha sub, score 0 216591012275 HMMPfam hit to PF02811, PHP domain, score 6.1e-40 216591012276 rhodanese superfamily protein; Provisional; Region: PRK05320 216591012277 Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518 216591012278 active site residue [active] 216591012279 HMMPfam hit to PF00581, Rhodanese-like domain, score 2.3e-07 216591012280 Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008 216591012281 glutamyl-queuosine tRNA(Asp) synthetase; Region: queuosine_YadB; TIGR03838 216591012282 active site 216591012283 HIGH motif; other site 216591012284 nucleotide binding site [chemical binding]; other site 216591012285 active site 216591012286 KMSKS motif; other site 216591012287 HMMPfam hit to PF00749, tRNA synthetases class I (E and Q), cata, score 3.7e-18 216591012288 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 216591012289 DEAD-like helicases superfamily; Region: DEXDc; smart00487 216591012290 ATP binding site [chemical binding]; other site 216591012291 Mg++ binding site [ion binding]; other site 216591012292 motif III; other site 216591012293 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591012294 nucleotide binding region [chemical binding]; other site 216591012295 ATP-binding site [chemical binding]; other site 216591012296 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 8.3e-33 216591012297 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 8.8e-69 216591012298 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 216591012299 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012300 Predicted periplasmic protein [General function prediction only]; Region: COG3895 216591012301 Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864 216591012302 1 probable transmembrane helix predicted for BCAL2414 by TMHMM2.0 at aa 7-29 216591012303 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012304 phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288 216591012305 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591012306 ATP-grasp domain; Region: ATP-grasp; pfam02222 216591012307 HMMPfam hit to PF02222, ATP-grasp domain, score 7.1e-85 216591012308 META domain; Region: META; pfam03724 216591012309 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012310 HMMPfam hit to PF03724, Domain of unknown function (306), score 1.5e-13 216591012311 Domain of unknown function (DUF4117); Region: DUF4117; pfam13491 216591012312 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 216591012313 Ftsk gamma domain; Region: Ftsk_gamma; pfam09397 216591012314 3 probable transmembrane helices predicted for BCAL2417 by TMHMM2.0 at aa 5-24, 39-61 and 74-96 216591012315 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012316 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591012317 HMMPfam hit to PF01580, FtsK/SpoIIIE family, score 1.4e-90 216591012318 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012319 Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282 216591012320 Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387 216591012321 Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723 216591012322 HMMPfam hit to PF00723, Glycosyl hydrolases family, score 8.1e-125 216591012323 Poly-beta-hydroxyalkanoate depolymerase [Lipid metabolism]; Region: DepA; COG4553 216591012324 PHB de-polymerase C-terminus; Region: PHB_depo_C; pfam06850 216591012325 HMMPfam hit to PF06850, PHB de-polymerase C-terminus, score 1.1e-138 216591012326 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591012327 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591012328 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591012329 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591012330 Predicted helix-turn-helix motif with score 1703.000, SD 4.99 at aa 20-41, sequence EAIRAVARTHGLSHSTVSQWYA 216591012331 putative transposase OrfB; Reviewed; Region: PHA02517 216591012332 HTH-like domain; Region: HTH_21; pfam13276 216591012333 Integrase core domain; Region: rve; pfam00665 216591012334 Integrase core domain; Region: rve_2; pfam13333 216591012335 HMMPfam hit to PF00665, Integrase core domain, score 5.1e-42 216591012336 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591012337 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591012338 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.8e-14 216591012339 ferredoxin; Provisional; Region: PRK06991 216591012340 Putative Fe-S cluster; Region: FeS; pfam04060 216591012341 4Fe-4S binding domain; Region: Fer4; pfam00037 216591012342 HMMPfam hit to PF04060, Putative Fe-S cluster, score 1.6e-16 216591012343 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 2.3e-08 216591012344 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591012345 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0001 216591012346 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591012347 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591012348 Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177 216591012349 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 216591012350 minor groove reading motif; other site 216591012351 helix-hairpin-helix signature motif; other site 216591012352 substrate binding pocket [chemical binding]; other site 216591012353 active site 216591012354 HMMPfam hit to PF00730, HhH-GPD superfamily base excision DNA repair, score 1.5e-18 216591012355 HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 5.7e-07 216591012356 PS01155 Endonuclease III family signature. 216591012357 EamA-like transporter family; Region: EamA; pfam00892 216591012358 Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950 216591012359 EamA-like transporter family; Region: EamA; pfam00892 216591012360 10 probable transmembrane helices predicted for BCAL2426 by TMHMM2.0 at aa 13-35, 39-61, 74-96, 101-123, 132-149, 154-173, 186-208, 218-240, 252-274 and 279-298 216591012361 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 8.5e-21 216591012362 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.1e-18 216591012363 Domain of unknown function (DUF1841); Region: DUF1841; pfam08897 216591012364 Cytochrome c553 [Energy production and conversion]; Region: COG2863 216591012365 HMMPfam hit to PF00034, Cytochrome c, score 0.0038 216591012366 PS00190 Cytochrome c family heme-binding site signature. 216591012367 Cytochrome c553 [Energy production and conversion]; Region: COG2863 216591012368 HMMPfam hit to PF00034, Cytochrome c, score 0.00021 216591012369 PS00190 Cytochrome c family heme-binding site signature. 216591012370 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 216591012371 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591012372 Walker A motif; other site 216591012373 ATP binding site [chemical binding]; other site 216591012374 Walker B motif; other site 216591012375 arginine finger; other site 216591012376 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 2.8e-06 216591012377 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 5.5e-10 216591012378 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012379 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3825 216591012380 HMMPfam hit to PF05762, VWA domain containing CoxE-like protein, score 0.0022 216591012381 Benzoate membrane transport protein; Region: BenE; pfam03594 216591012382 benzoate transporter; Region: benE; TIGR00843 216591012383 HMMPfam hit to PF03594, Benzoate membrane transport protein, score 1.2e-222 216591012384 11 probable transmembrane helices predicted for BCAL2432 by TMHMM2.0 at aa 21-43, 58-77, 84-103, 108-128, 135-153, 158-176, 183-205, 215-237, 306-328, 333-355 and 375-397 216591012385 HMMPfam hit to PF00860, Permease family, score 0.0011 216591012386 Predicted helix-turn-helix motif with score 999.000, SD 2.59 at aa 42-63, sequence VLMFQAGRAAHLTDAQISSWIW 216591012387 transaldolase-like protein; Provisional; Region: PTZ00411 216591012388 Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957 216591012389 active site 216591012390 dimer interface [polypeptide binding]; other site 216591012391 catalytic residue [active] 216591012392 HMMPfam hit to PF00923, Transaldolase, score 1.6e-147 216591012393 PS01054 Transaldolase signature 1. 216591012394 PS00958 Transaldolase active site. 216591012395 Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588 216591012396 dimer interface [polypeptide binding]; other site 216591012397 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591012398 HMMPfam hit to PF06983, 3-demethylubiquinone-9 3-methyltransfera, score 8.6e-07 216591012399 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/, score 4.9e-08 216591012400 Na+/proline symporter [Amino acid transport and metabolism / General function prediction only]; Region: PutP; COG0591 216591012401 Na binding site [ion binding]; other site 216591012402 13 probable transmembrane helices predicted for BCAL2435 by TMHMM2.0 at aa 4-26, 47-69, 79-101, 122-144, 159-181, 194-216, 236-258, 279-301, 331-353, 383-405, 409-431, 436-458 and 473-495 216591012403 HMMPfam hit to PF00474, Sodium:solute symporter family, score 1.9e-05 216591012404 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591012405 Protein of unknown function (DUF3311); Region: DUF3311; pfam11755 216591012406 2 probable transmembrane helices predicted for BCAL2436 by TMHMM2.0 at aa 54-71 and 81-103 216591012407 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 216591012408 2 probable transmembrane helices predicted for BCAL2438 by TMHMM2.0 at aa 20-42 and 52-71 216591012409 Protein of unknown function (DUF2029); Region: DUF2029; pfam09594 216591012410 10 probable transmembrane helices predicted for BCAL2439 by TMHMM2.0 at aa 21-43, 117-139, 152-174, 189-211, 218-240, 250-269, 281-303, 318-340, 361-378 and 383-402 216591012411 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012412 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591012413 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012414 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012415 MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032 216591012416 putative active site [active] 216591012417 Chorismate lyase; Region: Chor_lyase; cl01230 216591012418 HMMPfam hit to PF04345, Chorismate lyase, score 6.8e-08 216591012419 heat shock protein 90; Provisional; Region: PRK05218 216591012420 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591012421 ATP binding site [chemical binding]; other site 216591012422 Mg2+ binding site [ion binding]; other site 216591012423 G-X-G motif; other site 216591012424 HMMPfam hit to PF00183, Hsp90 protein, score 1.3e-103 216591012425 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5.3e-09 216591012426 PS00298 Heat shock hsp90 proteins family signature. 216591012427 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591012428 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591012429 DNA-binding site [nucleotide binding]; DNA binding site 216591012430 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591012431 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591012432 homodimer interface [polypeptide binding]; other site 216591012433 catalytic residue [active] 216591012434 HMMPfam hit to PF00155, Aminotransferase class I and II, score 6.7e-11 216591012435 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 1.9e-14 216591012436 Glyoxalase-like domain; Region: Glyoxalase_3; pfam13468 216591012437 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 216591012438 EamA-like transporter family; Region: EamA; pfam00892 216591012439 10 probable transmembrane helices predicted for BCAL2445 by TMHMM2.0 at aa 7-29, 39-56, 69-89, 94-116, 123-140, 144-166, 179-201, 216-238, 251-269 and 273-292 216591012440 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 7.8e-12 216591012441 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.5e-10 216591012442 Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436 216591012443 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591012444 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591012445 homodimer interface [polypeptide binding]; other site 216591012446 catalytic residue [active] 216591012447 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.9e-13 216591012448 This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199 216591012449 homotrimer interaction site [polypeptide binding]; other site 216591012450 putative active site [active] 216591012451 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 1.4e-17 216591012452 Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384 216591012453 hydroxyproline-2-epimerase; Provisional; Region: PRK13971 216591012454 HMMPfam hit to PF02567, Phenazine biosynthesis-like protein, score 2.3e-61 216591012455 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591012456 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591012457 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591012458 metal binding site [ion binding]; metal-binding site 216591012459 active site 216591012460 I-site; other site 216591012461 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 216591012462 2 probable transmembrane helices predicted for BCAL2449 by TMHMM2.0 at aa 37-59 and 310-332 216591012463 HMMPfam hit to PF00990, GGDEF domain, score 3.2e-45 216591012464 HMMPfam hit to PF00563, EAL domain, score 2.3e-112 216591012465 Chromate transporter; Region: Chromate_transp; pfam02417 216591012466 chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937 216591012467 Chromate transporter; Region: Chromate_transp; pfam02417 216591012468 8 probable transmembrane helices predicted for BCAL2450 by TMHMM2.0 at aa 15-37, 89-111, 121-143, 164-186, 206-225, 232-254, 297-319 and 382-401 216591012469 HMMPfam hit to PF02417, Chromate transporter, score 1.7e-06 216591012470 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012471 Bacterial Transmembrane Pair family; Region: BTP; pfam05232 216591012472 Bacterial Transmembrane Pair family; Region: BTP; pfam05232 216591012473 HMMPfam hit to PF05232, Bacterial Transmembrane Pair family, score 1.1e-30 216591012474 4 probable transmembrane helices predicted for BCAL2451 by TMHMM2.0 at aa 16-38, 48-67, 87-109 and 113-135 216591012475 HMMPfam hit to PF05232, Bacterial Transmembrane Pair family, score 4e-27 216591012476 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591012477 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591012478 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591012479 dimerization interface [polypeptide binding]; other site 216591012480 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.3e-17 216591012481 Predicted helix-turn-helix motif with score 1575.000, SD 4.55 at aa 18-39, sequence GSFTAAARKLGKRQSTVSEAIA 216591012482 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.9e-15 216591012483 Copper resistance protein D; Region: CopD; cl00563 216591012484 4 probable transmembrane helices predicted for BCAL2453 by TMHMM2.0 at aa 4-26, 52-74, 84-106 and 127-149 216591012485 DNA topoisomerase IV subunit A; Validated; Region: PRK05561 216591012486 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187 216591012487 CAP-like domain; other site 216591012488 active site 216591012489 primary dimer interface [polypeptide binding]; other site 216591012490 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 216591012491 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 0.00062 216591012492 HMMPfam hit to PF00521, DNA gyrase/topoisomerase IV, subunit A, score 2.9e-234 216591012493 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591012494 DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559 216591012495 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591012496 ATP binding site [chemical binding]; other site 216591012497 Mg2+ binding site [ion binding]; other site 216591012498 G-X-G motif; other site 216591012499 TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822 216591012500 anchoring element; other site 216591012501 dimer interface [polypeptide binding]; other site 216591012502 ATP binding site [chemical binding]; other site 216591012503 Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718 216591012504 active site 216591012505 metal binding site [ion binding]; metal-binding site 216591012506 DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986 216591012507 HMMPfam hit to PF00986, DNA gyrase B subunit, carboxyl terminus, score 2e-18 216591012508 PS00177 DNA topoisomerase II signature. 216591012509 HMMPfam hit to PF00204, DNA gyrase B, score 3.4e-28 216591012510 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and H, score 3e-21 216591012511 ABC transporter ATPase component; Reviewed; Region: PRK11147 216591012512 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591012513 Walker A/P-loop; other site 216591012514 ATP binding site [chemical binding]; other site 216591012515 Q-loop/lid; other site 216591012516 ABC transporter signature motif; other site 216591012517 Walker B; other site 216591012518 D-loop; other site 216591012519 H-loop/switch region; other site 216591012520 ABC transporter; Region: ABC_tran_2; pfam12848 216591012521 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 216591012522 HMMPfam hit to PF00005, ABC transporter, score 2.4e-44 216591012523 PS00211 ABC transporters family signature. 216591012524 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012525 HMMPfam hit to PF00005, ABC transporter, score 3.6e-52 216591012526 PS00211 ABC transporters family signature. 216591012527 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012528 Domain of unknown function (DUF4399); Region: DUF4399; pfam14347 216591012529 Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730 216591012530 Rubredoxin; Region: Rubredoxin; pfam00301 216591012531 iron binding site [ion binding]; other site 216591012532 HMMPfam hit to PF00301, Rubredoxin, score 9.6e-28 216591012533 PS00202 Rubredoxin signature. 216591012534 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591012535 S-adenosylmethionine binding site [chemical binding]; other site 216591012536 HMMPfam hit to PF01596, O-methyltransferase, score 8.6e-06 216591012537 4Fe-4S dicluster domain; Region: Fer4_7; pfam12838 216591012538 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 7.1e-06 216591012539 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591012540 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00062 216591012541 2 probable transmembrane helices predicted for BCAL2461 by TMHMM2.0 at aa 11-33 and 43-62 216591012542 RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937 216591012543 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591012544 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591012545 DNA binding residues [nucleotide binding] 216591012546 HMMPfam hit to PF04545, Sigma-70, region, score 4.1e-06 216591012547 HMMPfam hit to PF08281, Sigma-70, region, score 1.2e-09 216591012548 HMMPfam hit to PF04542, Sigma-70 region, score 1.3e-10 216591012549 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557 216591012550 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591012551 NAD(P) binding site [chemical binding]; other site 216591012552 active site 216591012553 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0016 216591012554 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.1e-31 216591012555 PS00216 Sugar transport proteins signature 1. 216591012556 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591012557 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591012558 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 9.2e-11 216591012559 ecotin; Provisional; Region: PRK03719 216591012560 secondary substrate binding site; other site 216591012561 primary substrate binding site; other site 216591012562 inhibition loop; other site 216591012563 dimerization interface [polypeptide binding]; other site 216591012564 HMMPfam hit to PF03974, Ecotin, score 4e-57 216591012565 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012566 2 probable transmembrane helices predicted for BCAL2468 by TMHMM2.0 at aa 19-41 and 51-73 216591012567 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591012568 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591012569 putative substrate translocation pore; other site 216591012570 13 probable transmembrane helices predicted for BCAL2470 by TMHMM2.0 at aa 31-53, 68-90, 97-119, 123-145, 158-180, 185-207, 219-236, 246-263, 283-305, 320-342, 349-371, 415-437 and 444-466 216591012571 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7e-57 216591012572 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012573 Predicted ATPase [General function prediction only]; Region: COG3911 216591012574 AAA domain; Region: AAA_28; pfam13521 216591012575 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012576 Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788 216591012577 alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400 216591012578 active site 216591012579 homotetramer interface [polypeptide binding]; other site 216591012580 HMMPfam hit to PF00982, Glycosyltransferase family, score 4.1e-175 216591012581 2 probable transmembrane helices predicted for BCAL2473 by TMHMM2.0 at aa 29-51 and 66-88 216591012582 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012583 2 probable transmembrane helices predicted for BCAL2474 by TMHMM2.0 at aa 7-29 and 33-55 216591012584 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012585 BcenGI8 216591012586 Bacterial conjugation TrbI-like protein; Region: TrbI; cl04242 216591012587 1 probable transmembrane helix predicted for BCAL2475 by TMHMM2.0 at aa 12-29 216591012588 PAAR motif; Region: PAAR_motif; pfam05488 216591012589 HMMPfam hit to PF05488, PAAR motif, score 4.8e-05 216591012590 HMMPfam hit to PF05488, PAAR motif, score 3.6e-05 216591012591 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012592 PS00018 EF-hand calcium-binding domain. 216591012593 lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222 216591012594 catalytic residue [active] 216591012595 Probable gene remnant. Similar to an internal region of Burkholderia vietnamiensis G4 hypothetical protein precursor UniProt:Q4BJ74 (EMBL:AAEH02000017) (932 aa) fasta scores: E()=5.9e-46, 48.052% id in 308 aa 216591012596 PS00018 EF-hand calcium-binding domain. 216591012597 Probable gene remnant. Similar to the N-terminal region of Bordetella bronchiseptica putative integrase UniProt:Q7WQ32 (EMBL:BX640438) (121 aa) fasta scores: E()=2.4e-15, 89.796% id in 49 aa 216591012598 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584 216591012599 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 216591012600 DNA-binding interface [nucleotide binding]; DNA binding site 216591012601 Integrase core domain; Region: rve; pfam00665 216591012602 HMMPfam hit to PF02796, Helix-turn-helix domain of resolvase, score 0.0028 216591012603 Predicted helix-turn-helix motif with score 2020.000, SD 6.07 at aa 18-39, sequence VSEREIARRLGISRNTVARYLS 216591012604 HMMPfam hit to PF00665, Integrase core domain, score 2.7e-25 216591012605 transposase/IS protein; Provisional; Region: PRK09183 216591012606 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591012607 Walker A motif; other site 216591012608 ATP binding site [chemical binding]; other site 216591012609 Walker B motif; other site 216591012610 HMMPfam hit to PF01695, IstB-like ATP binding protein, score 9.6e-88 216591012611 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012612 HMMPfam hit to PF00580, UvrD/REP helicase, score 4.3e-08 216591012613 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 216591012614 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 216591012615 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 216591012616 Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586 216591012617 HMMPfam hit to PF01609, Transposase DDE domain, score 3.6e-32 216591012618 Protein of unknown function (DUF1427); Region: DUF1427; pfam07235 216591012619 HMMPfam hit to PF07235, Protein of unknown function (DUF1427), score 7.1e-34 216591012620 2 probable transmembrane helices predicted for BCAL2481 by TMHMM2.0 at aa 5-22 and 27-49 216591012621 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591012622 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591012623 trimer interface [polypeptide binding]; other site 216591012624 eyelet of channel; other site 216591012625 HMMPfam hit to PF00267, Gram-negative porin, score 0.0047 216591012626 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 216591012627 HMMPfam hit to PF05976, Bacterial membrane protein of unknown functi, score 0.0069 216591012628 8 probable transmembrane helices predicted for BCAL2483 by TMHMM2.0 at aa 20-42, 91-113, 120-142, 146-168, 438-460, 464-483, 485-507 and 512-534 216591012629 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012630 Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589 216591012631 Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139 216591012632 Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589 216591012633 Domain of unknown function (DUF3390); Region: DUF3390; pfam11870 216591012634 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0013 216591012635 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591012636 Cysteine-rich domain; Region: CCG; pfam02754 216591012637 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 216591012638 Cysteine-rich domain; Region: CCG; pfam02754 216591012639 HMMPfam hit to PF02754, Cysteine-rich domain, score 3.6e-13 216591012640 HMMPfam hit to PF02754, Cysteine-rich domain, score 6.1e-11 216591012641 D-lactate dehydrogenase; Provisional; Region: PRK11183 216591012642 FAD binding domain; Region: FAD_binding_4; pfam01565 216591012643 D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330 216591012644 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591012645 HMMPfam hit to PF01565, FAD binding domain, score 2.1e-05 216591012646 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591012647 DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986 216591012648 The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451 216591012649 putative dimerization interface [polypeptide binding]; other site 216591012650 putative substrate binding pocket [chemical binding]; other site 216591012651 HMMPfam hit to PF03466, LysR substrate binding domain, score 7e-43 216591012652 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.7e-21 216591012653 PS00044 Bacterial regulatory proteins, lysR family signature. 216591012654 Predicted helix-turn-helix motif with score 1303.000, SD 3.62 at aa 16-37, sequence LHFTEAAEFLGIAQPPLSQQIL 216591012655 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084 216591012656 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 7.5e-24 216591012657 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591012658 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591012659 LysR substrate binding domain; Region: LysR_substrate; pfam03466 216591012660 dimerization interface [polypeptide binding]; other site 216591012661 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 1.2e-16 216591012662 Predicted helix-turn-helix motif with score 1297.000, SD 3.60 at aa 16-37, sequence GTLGGAARALALSHPTIGRRLR 216591012663 PS00044 Bacterial regulatory proteins, lysR family signature. 216591012664 Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413 216591012665 1 probable transmembrane helix predicted for BCAL2491 by TMHMM2.0 at aa 7-24 216591012666 Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671 216591012667 PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385 216591012668 active site 216591012669 5 probable transmembrane helices predicted for BCAL2492 by TMHMM2.0 at aa 20-42, 55-77, 100-117, 124-141 and 151-173 216591012670 HMMPfam hit to PF01569, PAP2 superfamily, score 6.5e-16 216591012671 Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4705 216591012672 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 216591012673 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 216591012674 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 216591012675 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 216591012676 HMMPfam hit to PF03988, Repeat of Unknown Function (DUF347), score 2.3e-15 216591012677 6 probable transmembrane helices predicted for BCAL2493 by TMHMM2.0 at aa 76-95, 100-122, 142-161, 165-187, 194-216 and 226-248 216591012678 HMMPfam hit to PF03988, Repeat of Unknown Function (DUF347), score 5.2e-17 216591012679 HMMPfam hit to PF03988, Repeat of Unknown Function (DUF347), score 3e-05 216591012680 HMMPfam hit to PF03988, Repeat of Unknown Function (DUF347), score 2e-13 216591012681 1 probable transmembrane helix predicted for BCAL2494 by TMHMM2.0 at aa 4-26 216591012682 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012683 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 216591012684 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 216591012685 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 216591012686 HMMPfam hit to PF03988, Repeat of Unknown Function (DUF347), score 9.4e-08 216591012687 6 probable transmembrane helices predicted for BCAL2495 by TMHMM2.0 at aa 43-62, 72-89, 96-118, 163-185, 192-211 and 221-243 216591012688 HMMPfam hit to PF03988, Repeat of Unknown Function (DUF347), score 3.4e-11 216591012689 HMMPfam hit to PF03988, Repeat of Unknown Function (DUF347), score 0.00024 216591012690 Interrupted by insertion sequence after codon 22. When complete, transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' 216591012691 HMMPfam hit to PF01609, Transposase DDE domain, score 3.6e-32 216591012692 Transposase, Mutator family; Region: Transposase_mut; pfam00872 216591012693 MULE transposase domain; Region: MULE; pfam10551 216591012694 HMMPfam hit to PF00872, Transposase, Mutator family, score 2.8e-204 216591012695 PS01007 Transposases, Mutator family, signature. 216591012696 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589 216591012697 Domain of unknown function (DUF4150); Region: DUF4150; pfam13665 216591012698 Uncharacterized protein conserved in bacteria (DUF2169); Region: DUF2169; pfam09937 216591012699 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 216591012700 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 216591012701 Gp5 C-terminal repeat (3 copies); Region: Gp5_C; pfam06715 216591012702 HMMPfam hit to PF06715, Gp5 C-terminal repeat (3 copies), score 0.01 216591012703 HMMPfam hit to PF06715, Gp5 C-terminal repeat (3 copies), score 0.0075 216591012704 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 3.2e-52 216591012705 Protein of unknown function (DUF3592); Region: DUF3592; pfam12158 216591012706 2 probable transmembrane helices predicted for BCAL2505 by TMHMM2.0 at aa 5-22 and 100-122 216591012707 metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459 216591012708 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012709 phage/plasmid-like protein TIGR03299; Region: LGT_TIGR03299 216591012710 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012711 YqaJ-like viral recombinase domain; Region: YqaJ; cl09232 216591012712 3 probable transmembrane helices predicted for BCAL2512 by TMHMM2.0 at aa 5-27, 37-56 and 68-90 216591012713 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012714 Methyltransferase domain; Region: Methyltransf_27; pfam13708 216591012715 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591012716 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591012717 non-specific DNA binding site [nucleotide binding]; other site 216591012718 salt bridge; other site 216591012719 sequence-specific DNA binding site [nucleotide binding]; other site 216591012720 HMMPfam hit to PF01381, Helix-turn-helix, score 2.9e-12 216591012721 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 216591012722 HMMPfam hit to PF01757, Acyltransferase family, score 1.9e-64 216591012723 10 probable transmembrane helices predicted for BCAL2519 by TMHMM2.0 at aa 45-67, 88-107, 146-168, 175-194, 209-228, 235-252, 257-276, 285-307, 322-344 and 357-376 216591012724 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012725 Probable gene remnant. CDS lacks appropriate translational start site. Similar to the C-terminal region of Azoarcus sp. (strain EbN1) hypothetical protein UniProt:Q5P5E4 (EMBL:CR555306) (962 aa) fasta scores: E()=0, 90.154% id in 650 aa 216591012726 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012727 Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651 216591012728 DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972 216591012729 catalytic residues [active] 216591012730 1 probable transmembrane helix predicted for BCAL2522 by TMHMM2.0 at aa 21-43 216591012731 HMMPfam hit to PF01323, DSBA-like thioredoxin domain, score 2.3e-05 216591012732 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012733 DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242 216591012734 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591012735 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 216591012736 dimerization interface [polypeptide binding]; other site 216591012737 substrate binding pocket [chemical binding]; other site 216591012738 HMMPfam hit to PF03466, LysR substrate binding domain, score 2e-35 216591012739 Predicted helix-turn-helix motif with score 1598.000, SD 4.63 at aa 90-111, sequence RGLLRIALSDGISPSHLSNLLA 216591012740 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1e-22 216591012741 PS00044 Bacterial regulatory proteins, lysR family signature. 216591012742 Predicted helix-turn-helix motif with score 1598.000, SD 4.63 at aa 16-37, sequence LSFTRAAERLHIEQSPLSRSIR 216591012743 Domain of unknown function (DUF3817); Region: DUF3817; pfam12823 216591012744 3 probable transmembrane helices predicted for BCAL2523A by TMHMM2.0 at aa 29-51, 61-83 and 90-109 216591012745 transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393 216591012746 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 216591012747 conserved cys residue [active] 216591012748 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591012749 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591012750 HMMPfam hit to PF01965, DJ-1/PfpI family, score 4.1e-10 216591012751 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 2.1e-08 216591012752 Predicted helix-turn-helix motif with score 1142.000, SD 3.08 at aa 229-250, sequence LTLKDMAGRAAMSSRTLNRRFQ 216591012753 PS00041 Bacterial regulatory proteins, araC family signature. 216591012754 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 5.5e-10 216591012755 Predicted helix-turn-helix motif with score 986.000, SD 3.08 at aa 294-315, sequence SLREHFGRIVGVSPTAYRKSFN 216591012756 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591012757 putative substrate translocation pore; other site 216591012758 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.3e-42 216591012759 11 probable transmembrane helices predicted for BCAL2525 by TMHMM2.0 at aa 22-44, 59-81, 93-115, 120-142, 149-171, 175-194, 225-247, 257-279, 286-305, 315-334 and 346-368 216591012760 Probable gene remnant. Similar to the C-terminal region of Azotobacter sp. FA8 hypothetical protein UniProt:Q8KRE7 (EMBL:ASP496234) (299 aa) fasta scores: E()=1.3e-15, 67.188% id in 64 aa 216591012761 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 216591012762 Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg3; cd01282 216591012763 DNA binding residues [nucleotide binding] 216591012764 putative dimer interface [polypeptide binding]; other site 216591012765 HMMPfam hit to PF00376, MerR family regulatory protein, score 6.8e-10 216591012766 Predicted helix-turn-helix motif with score 1431.000, SD 4.06 at aa 1-22, sequence MTIGELAHKTGASRRSIRHYDD 216591012767 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591012768 Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886 216591012769 1 probable transmembrane helix predicted for BCAL2527 by TMHMM2.0 at aa 7-29 216591012770 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 9e-18 216591012771 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591012772 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 3e-12 216591012773 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591012774 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591012775 The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417 216591012776 substrate binding pocket [chemical binding]; other site 216591012777 dimerization interface [polypeptide binding]; other site 216591012778 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.4e-10 216591012779 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.5e-15 216591012780 PS00044 Bacterial regulatory proteins, lysR family signature. 216591012781 Predicted helix-turn-helix motif with score 1013.000, SD 2.64 at aa 19-40, sequence ANVTRAARRLAISQPALSAQLA 216591012782 SnoaL-like domain; Region: SnoaL_2; pfam12680 216591012783 HMMPfam hit to PF07366, SnoaL-like polyketide cyclase, score 0.0027 216591012784 Protein of unknown function (DUF3423); Region: DUF3423; pfam11903 216591012785 HMMPfam hit to PF00557, metallopeptidase family M24, score 9.1e-78 216591012786 Transposase; Region: HTH_Tnp_1; pfam01527 216591012787 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591012788 CDS lacks appropriate translational start site. It is likely that this CDS encodes the C-terminal region of a larger protein encompassing the upstream CDS. A translational frameshift possibly occurs after residue 86 of the upstream overlapping CDS 216591012789 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591012790 Probable gene remnant. Similar to an internal region of Escherichia coli transposase UniProt:Q3ZTZ8 (EMBL:AY258503 (342 aa) fasta scores: E()=7.9e-13, 50.649% id in 77 aa 216591012791 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591012792 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591012793 PGAP1-like protein; Region: PGAP1; pfam07819 216591012794 HMMPfam hit to PF00975, Thioesterase domain, score 0.00012 216591012795 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 2.6e-25 216591012796 transcriptional regulator; Provisional; Region: PRK10632 216591012797 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591012798 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591012799 putative effector binding pocket; other site 216591012800 dimerization interface [polypeptide binding]; other site 216591012801 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.4e-13 216591012802 Predicted helix-turn-helix motif with score 1186.000, SD 3.23 at aa 17-38, sequence GSLVSAARRFGLSPSMAGKHVS 216591012803 PS00044 Bacterial regulatory proteins, lysR family signature. 216591012804 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.9e-53 216591012805 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591012806 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591012807 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.4e-16 216591012808 Predicted helix-turn-helix motif with score 1549.000, SD 4.46 at aa 29-50, sequence LSVRRLAEEVGVKPASLYHHFP 216591012809 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591012810 GST_N family, Saccharomyces cerevisiae GTT2-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT2. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing...; Region: GST_N_GTT2_like; cd03051 216591012811 putative C-terminal domain interface [polypeptide binding]; other site 216591012812 putative GSH binding site (G-site) [chemical binding]; other site 216591012813 putative dimer interface [polypeptide binding]; other site 216591012814 C-terminal, alpha helical domain of GTT2-like Glutathione S-transferases; Region: GST_C_GTT2_like; cd03182 216591012815 putative N-terminal domain interface [polypeptide binding]; other site 216591012816 putative dimer interface [polypeptide binding]; other site 216591012817 putative substrate binding pocket (H-site) [chemical binding]; other site 216591012818 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 1.4e-07 216591012819 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 8.9e-14 216591012820 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591012821 transcriptional activator TtdR; Provisional; Region: PRK09801 216591012822 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479 216591012823 putative effector binding pocket; other site 216591012824 putative dimerization interface [polypeptide binding]; other site 216591012825 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.2e-46 216591012826 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2e-21 216591012827 PS00044 Bacterial regulatory proteins, lysR family signature. 216591012828 Predicted helix-turn-helix motif with score 1946.000, SD 5.81 at aa 17-38, sequence RSLAAAARELGVTPPAVSKRLA 216591012829 alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561 216591012830 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1e-19 216591012831 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583 216591012832 3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402 216591012833 substrate binding site [chemical binding]; other site 216591012834 ligand binding site [chemical binding]; other site 216591012835 HMMPfam hit to PF00330, Aconitase family (aconitate hydratase), score 5e-194 216591012836 PS00450 Aconitase family signature 1. 216591012837 PS01244 Aconitase family signature 2. 216591012838 isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641 216591012839 Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577 216591012840 substrate binding site [chemical binding]; other site 216591012841 HMMPfam hit to PF00694, Aconitase C-terminal domain, score 8.5e-38 216591012842 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591012843 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591012844 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.2e-13 216591012845 Predicted helix-turn-helix motif with score 1311.000, SD 3.65 at aa 40-61, sequence TSITDLTRAMRLAQGSLYKAFK 216591012846 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012847 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591012848 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012849 12 probable transmembrane helices predicted for BCAL2545 by TMHMM2.0 at aa 13-35, 50-72, 79-98, 103-125, 138-160, 165-187, 219-241, 251-273, 280-299, 303-325, 345-367 and 371-390 216591012850 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.2e-32 216591012851 Probable gene remnant. Similar to the N-terminal region of Bordetella parapertussis CsaA protein secretion chaperone UniProt:Q7W9Y8 (EMBL:BX640427) (112 aa) fasta scores: E()=2.7e-12, 55.172% id in 87 aa. CDS contains a frameshift after codon 66 216591012852 Probable gene remnant. Similar to an internal region of Burkholderia pseudomallei (Pseudomonas pseudomallei) MAP2 methionine aminopeptidase UniProt:Q63SV9 (EMBL:BX571965) (272 aa) fasta scores: E()=7.6e-06, 58.696% id in 46 aa 216591012853 Protein of unknown function (DUF1525); Region: DUF1525; pfam07511 216591012854 Probable gene remnant. CDS lacks appropriate translational start site. Similar to the C-terminal region of Azoarcus sp. (strain EbN1) hypothetical protein UniProt:Q5P571 (EMBL:CR555306) (314 aa) fasta scores: E()=7.7e-48, 70.764% id in 301 aa 216591012855 HMMPfam hit to PF07513, Protein of unknown function (DUF1527), score 8.3e-164 216591012856 integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755 216591012857 3 probable transmembrane helices predicted for BCAL2551 by TMHMM2.0 at aa 16-38, 58-75 and 96-115 216591012858 TraG-like protein, N-terminal region; Region: TraG_N; pfam07916 216591012859 5 probable transmembrane helices predicted for BCAL2552 by TMHMM2.0 at aa 20-42, 71-88, 360-382, 389-411 and 451-473 216591012860 PS00211 ABC transporters family signature. 216591012861 1 probable transmembrane helix predicted for BCAL2553 by TMHMM2.0 at aa 56-78 216591012862 PIN domain; Region: PIN_3; cl17397 216591012863 Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877 216591012864 integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760 216591012865 Putative helicase; Region: TraI_2; pfam07514 216591012866 Protein of unknown function (DUF1528); Region: DUF1528; pfam07515 216591012867 HMMPfam hit to PF07514, Putative helicase, score 2.3e-182 216591012868 HMMPfam hit to PF07515, Protein of unknown function (DUF1528), score 1e-81 216591012869 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 216591012870 Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730 216591012871 Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492 216591012872 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591012873 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 6.2e-10 216591012874 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 0.0024 216591012875 Rrf2 family protein; Region: rrf2_super; TIGR00738 216591012876 Transcriptional regulator; Region: Rrf2; pfam02082 216591012877 HMMPfam hit to PF02082, Transcriptional regulator, score 5.1e-33 216591012878 HMMPfam hit to PF08279, HTH domain, score 0.0002 216591012879 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591012880 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591012881 non-specific DNA binding site [nucleotide binding]; other site 216591012882 salt bridge; other site 216591012883 sequence-specific DNA binding site [nucleotide binding]; other site 216591012884 HMMPfam hit to PF01381, Helix-turn-helix, score 8e-13 216591012885 Predicted helix-turn-helix motif with score 1134.000, SD 3.05 at aa 33-54, sequence LAQEVLAEQAGIARSHMGKIER 216591012886 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591012887 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 216591012888 dimerization interface [polypeptide binding]; other site 216591012889 substrate binding pocket [chemical binding]; other site 216591012890 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.2e-25 216591012891 Probable gene remnant. CDS is truncated by the insertion of the upstream IS element. Similar to the C-terminal region of Azoarcus sp. (strain EbN1) integrase Int UniProt:Q5P5J0 (EMBL:CR555306) (641 aa) fasta scores: E()=2.6e-34, 62.500% id in 152 aa 216591012892 DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484 216591012893 IstB-like ATP binding N-terminal; Region: IstB_IS21_ATP; pfam08483 216591012894 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591012895 Walker A motif; other site 216591012896 ATP binding site [chemical binding]; other site 216591012897 Walker B motif; other site 216591012898 arginine finger; other site 216591012899 HMMPfam hit to PF01695, IstB-like ATP binding protein, score 1e-109 216591012900 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012901 HMMPfam hit to PF08483, IstB-like ATP binding N-terminal, score 3.4e-14 216591012902 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257 216591012903 DNA binding residues [nucleotide binding] 216591012904 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584 216591012905 Integrase core domain; Region: rve; pfam00665 216591012906 Integrase core domain; Region: rve_3; cl15866 216591012907 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584 216591012908 HMMPfam hit to PF00665, Integrase core domain, score 1.6e-28 216591012909 Predicted helix-turn-helix motif with score 1142.000, SD 3.08 at aa 23-44, sequence LTHRQISRAIGISVGAVSKFAA 216591012910 UPF0489 domain; Region: UPF0489; pfam12640 216591012911 UPF0489 domain; Region: UPF0489; pfam12640 216591012912 PS00024 Hemopexin domain signature. 216591012913 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012914 Similar to the C-terminus of Chromobacterium violaceum protein UmuC SWALL:Q7NUT5 (EMBL:AE016919) (301 aa) fasta scores: E(): 5.5e-12, 40.33% id in 119 aa 216591012915 Cupin; Region: Cupin_6; pfam12852 216591012916 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591012917 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591012918 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3e-08 216591012919 Uncharacterized conserved protein [Function unknown]; Region: COG2128 216591012920 Carboxymuconolactone decarboxylase family; Region: CMD; cl00460 216591012921 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 8e-08 216591012922 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591012923 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591012924 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 216591012925 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 216591012926 Walker A/P-loop; other site 216591012927 ATP binding site [chemical binding]; other site 216591012928 Q-loop/lid; other site 216591012929 ABC transporter signature motif; other site 216591012930 Walker B; other site 216591012931 D-loop; other site 216591012932 H-loop/switch region; other site 216591012933 HMMPfam hit to PF00005, ABC transporter, score 3e-62 216591012934 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012935 PS00211 ABC transporters family signature. 216591012936 CDS contains a nonsense mutation (amber) after codon 197. Similar to Pseudomonas aeruginosa hypothetical protein UniProt:Q9I1F0 (EMBL:AE004659) (399 aa) fasta scores: E()=1.8e-108, 69.873% id in 395 aa 216591012937 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591012938 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591012939 dimer interface [polypeptide binding]; other site 216591012940 conserved gate region; other site 216591012941 putative PBP binding loops; other site 216591012942 ABC-ATPase subunit interface; other site 216591012943 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.5e-18 216591012944 5 probable transmembrane helices predicted for BCAL2576 by TMHMM2.0 at aa 59-81, 113-135, 156-175, 179-201 and 208-230 216591012945 Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139 216591012946 conserved cys residue [active] 216591012947 HMMPfam hit to PF01965, DJ-1/PfpI family, score 1.8e-05 216591012948 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591012949 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591012950 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 5.4e-20 216591012951 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591012952 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591012953 putative effector binding pocket; other site 216591012954 dimerization interface [polypeptide binding]; other site 216591012955 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.1e-11 216591012956 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.6e-48 216591012957 Similar to Burkholderia pseudomallei (Pseudomonas pseudomallei) putative transposase protein UniProt:Q63YU9 (EMBL:BX571965) (276 aa) fasta scores: E()=1.7e-105, 98.545% id in 275 aa. Frameshift after codon 155 caused by 2bp insertion. 216591012958 HMMPfam hit to PF00665, Integrase core domain, score 1.6e-41 216591012959 Transposase; Region: HTH_Tnp_1; pfam01527 216591012960 HMMPfam hit to PF01527, Transposase, score 9.7e-30 216591012961 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 216591012962 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 2e-18 216591012963 Nitrilases, cyanide hydratase (CH)s, and similar proteins (class 1 nitrilases); Region: nitrilases_CHs; cd07564 216591012964 Predicted amidohydrolase [General function prediction only]; Region: COG0388 216591012965 putative active site [active] 216591012966 catalytic triad [active] 216591012967 putative dimer interface [polypeptide binding]; other site 216591012968 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 9.6e-68 216591012969 PS00920 Nitrilases / cyanide hydratase signature 1. 216591012970 PS00921 Nitrilases / cyanide hydratase active site signature. 216591012971 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591012972 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591012973 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 4.4e-09 216591012974 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 9e-07 216591012975 Predicted helix-turn-helix motif with score 1779.000, SD 5.25 at aa 230-251, sequence LDIARIAQTLGMSVSSLYRAFA 216591012976 Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557 216591012977 Probable gene remnant. CDS lacks appropriate stop codon due to the insertion of the downstream IS element. Similar to Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) transposase, IS4 UniProt:Q46NI7 (EMBL:CP000092) (481 aa) fasta scores: E()=1.4e-130, 70.217% id in 460 aa 216591012978 HMMPfam hit to PF01609, Transposase DDE domain, score 6.5e-12 216591012979 PS00017 ATP/GTP-binding site motif A (P-loop). 216591012980 Probable gene remnant. Similar to the C-terminal region of Xanthomonas campestris insertion element IS476 hypothetical 39.2 kDa protein SWALL:YI61_XANCV (SWALL:P25438) (346 aa) fasta scores: E(): 2.6e-43, 66.66% id in 168 aa. CDS contains a frame shift mutation after codon 65 216591012981 HMMPfam hit to PF00665, Integrase core domain, score 1.6e-41 216591012982 CDS is interrupted by IS element insertion after codon 236. Similar to Burkholderia cenocepacia HI2424 hypothetical protein UniProt:Q4LZD5 (EMBL:AAHL01000003) (402 aa) fasta scores: E()=6.1e-42, 37.568% id in 370 aa 216591012983 Transposase; Region: HTH_Tnp_1; pfam01527 216591012984 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591012985 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591012986 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591012987 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591012988 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591012989 HMMPfam hit to PF01548, Transposase, score 2.9e-12 216591012990 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591012991 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591012992 Protein of unknown function (DUF3987); Region: DUF3987; pfam13148 216591012993 Predicted helix-turn-helix motif with score 1213.000, SD 3.32 at aa 33-54, sequence LTTEELATALSLSAQSIRKRYA 216591012994 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 216591012995 active site 216591012996 DNA binding site [nucleotide binding] 216591012997 Int/Topo IB signature motif; other site 216591012998 HMMPfam hit to PF00589, Phage integrase family, score 5.6e-07 216591012999 CDS contains a frameshift and an internal deletion after codon 381. Similar to Burkholderia mallei ABC transporter, ATP-binding protein UniProt:Q62LA0 (EMBL:CP000010) (446 aa) fasta scores: E()=3.9e-124, 92.152% id in 446 aa 216591013000 HMMPfam hit to PF00005, ABC transporter, score 3.9e-57 216591013001 PS00211 ABC transporters family signature. 216591013002 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013003 ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986 216591013004 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591013005 dimer interface [polypeptide binding]; other site 216591013006 conserved gate region; other site 216591013007 putative PBP binding loops; other site 216591013008 ABC-ATPase subunit interface; other site 216591013009 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591013010 dimer interface [polypeptide binding]; other site 216591013011 conserved gate region; other site 216591013012 putative PBP binding loops; other site 216591013013 ABC-ATPase subunit interface; other site 216591013014 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.4e-05 216591013015 12 probable transmembrane helices predicted for BCAL2603 by TMHMM2.0 at aa 26-48, 68-90, 103-125, 135-157, 207-229, 244-266, 345-367, 382-404, 421-443, 447-469, 490-512 and 552-571 216591013016 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.4e-05 216591013017 The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013 216591013018 HAMP domain; Region: HAMP; pfam00672 216591013019 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591013020 dimer interface [polypeptide binding]; other site 216591013021 phosphorylation site [posttranslational modification] 216591013022 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591013023 ATP binding site [chemical binding]; other site 216591013024 Mg2+ binding site [ion binding]; other site 216591013025 G-X-G motif; other site 216591013026 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 7.4e-26 216591013027 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.6e-13 216591013028 HMMPfam hit to PF00672, HAMP domain, score 2.1e-15 216591013029 2 probable transmembrane helices predicted for BCAL2605 by TMHMM2.0 at aa 10-29 and 147-169 216591013030 osmolarity response regulator; Provisional; Region: ompR; PRK09468 216591013031 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591013032 active site 216591013033 phosphorylation site [posttranslational modification] 216591013034 intermolecular recognition site; other site 216591013035 dimerization interface [polypeptide binding]; other site 216591013036 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591013037 DNA binding site [nucleotide binding] 216591013038 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 2.5e-21 216591013039 HMMPfam hit to PF00072, Response regulator receiver domain, score 8e-40 216591013040 Heavy-metal resistance; Region: Metal_resist; pfam13801 216591013041 Mitochondrial ribosomal protein subunit L20; Region: MRP-L20; pfam12824 216591013042 1 probable transmembrane helix predicted for BCAL2607 by TMHMM2.0 at aa 7-26 216591013043 Pirin-related protein [General function prediction only]; Region: COG1741 216591013044 Pirin; Region: Pirin; pfam02678 216591013045 HMMPfam hit to PF02678, Pirin, score 1.8e-33 216591013046 lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096 216591013047 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591013048 substrate binding pocket [chemical binding]; other site 216591013049 membrane-bound complex binding site; other site 216591013050 hinge residues; other site 216591013051 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 5e-90 216591013052 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591013053 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591013054 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591013055 dimer interface [polypeptide binding]; other site 216591013056 conserved gate region; other site 216591013057 putative PBP binding loops; other site 216591013058 ABC-ATPase subunit interface; other site 216591013059 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.2e-30 216591013060 5 probable transmembrane helices predicted for BCAL2610 by TMHMM2.0 at aa 15-37, 49-71, 91-109, 150-172 and 192-214 216591013061 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591013062 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591013063 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591013064 dimer interface [polypeptide binding]; other site 216591013065 conserved gate region; other site 216591013066 putative PBP binding loops; other site 216591013067 ABC-ATPase subunit interface; other site 216591013068 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.2e-16 216591013069 5 probable transmembrane helices predicted for BCAL2611 by TMHMM2.0 at aa 20-42, 63-85, 105-127, 167-189 and 199-221 216591013070 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591013071 Predicted helix-turn-helix motif with score 1046.000, SD 2.75 at aa 130-151, sequence YGEIEAARAYGMSTFTMYRRVI 216591013072 ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; Region: HisP; COG4598 216591013073 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 216591013074 Walker A/P-loop; other site 216591013075 ATP binding site [chemical binding]; other site 216591013076 Q-loop/lid; other site 216591013077 ABC transporter signature motif; other site 216591013078 Walker B; other site 216591013079 D-loop; other site 216591013080 H-loop/switch region; other site 216591013081 HMMPfam hit to PF00005, ABC transporter, score 2.9e-65 216591013082 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013083 PS00211 ABC transporters family signature. 216591013084 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591013085 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.3e-21 216591013086 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591013087 The C-terminal substrate biniding domain of an uncharacterized LysR-like transcriptional regulator Pa0477 related to DntR, contains the type 2 periplasmic binding fold; Region: PBP2_Pa0477; cd08468 216591013088 putative substrate binding pocket [chemical binding]; other site 216591013089 dimerization interface [polypeptide binding]; other site 216591013090 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.7e-18 216591013091 Predicted helix-turn-helix motif with score 1327.000, SD 3.71 at aa 24-45, sequence RSVAAAAHELALSPSALSHALA 216591013092 PS00044 Bacterial regulatory proteins, lysR family signature. 216591013093 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.7e-22 216591013094 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591013095 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591013096 trimer interface [polypeptide binding]; other site 216591013097 eyelet of channel; other site 216591013098 Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347 216591013099 Nitrogen regulatory protein P-II; Region: P-II; smart00938 216591013100 HMMPfam hit to PF00543, Nitrogen regulatory protein P-II, score 1.3e-68 216591013101 PS00638 P-II protein C-terminal region signature. 216591013102 PS00496 P-II protein urydylation site. 216591013103 NAD synthetase; Provisional; Region: PRK13981 216591013104 Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570 216591013105 multimer interface [polypeptide binding]; other site 216591013106 active site 216591013107 catalytic triad [active] 216591013108 protein interface 1 [polypeptide binding]; other site 216591013109 NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553 216591013110 homodimer interface [polypeptide binding]; other site 216591013111 NAD binding pocket [chemical binding]; other site 216591013112 ATP binding pocket [chemical binding]; other site 216591013113 Mg binding site [ion binding]; other site 216591013114 active-site loop [active] 216591013115 HMMPfam hit to PF02540, NAD synthase, score 1.8e-90 216591013116 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 2.8e-12 216591013117 Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497 216591013118 Protein of unknown function, DUF482; Region: DUF482; pfam04339 216591013119 HMMPfam hit to PF04339, Protein of unknown function, DUF482, score 3.9e-164 216591013120 Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933 216591013121 Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472 216591013122 Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915 216591013123 Fibronectin type III-like domain; Region: Fn3-like; pfam14310 216591013124 HMMPfam hit to PF01915, Glycosyl hydrolase family 3 C termina, score 2.7e-68 216591013125 HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N termina, score 8.3e-95 216591013126 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013127 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 216591013128 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591013129 PS00041 Bacterial regulatory proteins, araC family signature. 216591013130 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 7.6e-07 216591013131 The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456 216591013132 GIY-YIG motif/motif A; other site 216591013133 putative active site [active] 216591013134 putative metal binding site [ion binding]; other site 216591013135 HMMPfam hit to PF01541, GIY-YIG catalytic domain, score 6.9e-13 216591013136 Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412 216591013137 dimer interface [polypeptide binding]; other site 216591013138 substrate binding site [chemical binding]; other site 216591013139 metal binding sites [ion binding]; metal-binding site 216591013140 HMMPfam hit to PF00719, Inorganic pyrophosphatase, score 8e-58 216591013141 PS00387 Inorganic pyrophosphatase signature. 216591013142 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591013143 Uncharacterized Saccharopolyspora spinosa aldehyde dehydrogenase (AAS00426)-like; Region: ALDH_AAS00426; cd07109 216591013144 NAD(P) binding site [chemical binding]; other site 216591013145 catalytic residues [active] 216591013146 catalytic residues [active] 216591013147 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.7e-207 216591013148 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591013149 PS00070 Aldehyde dehydrogenases cysteine active site. 216591013150 putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR), subgroup 3, classical (c) SDR; Region: BKR_3_SDR_c; cd05345 216591013151 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231 216591013152 putative NAD(P) binding site [chemical binding]; other site 216591013153 active site 216591013154 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.4e-30 216591013155 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591013156 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591013157 putative substrate translocation pore; other site 216591013158 12 probable transmembrane helices predicted for BCAL2625 by TMHMM2.0 at aa 23-40, 62-84, 97-119, 123-145, 152-174, 184-206, 252-274, 284-306, 319-338, 342-364, 371-393 and 408-427 216591013159 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.7e-60 216591013160 Helix-turn-helix domain; Region: HTH_17; pfam12728 216591013161 Predicted helix-turn-helix motif with score 1033.000, SD 2.71 at aa 3-24, sequence HTVEDTAARLRVHPKTVLRFIR 216591013162 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591013163 Domain of unknown function (DUF4180); Region: DUF4180; pfam13788 216591013164 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 0.00043 216591013165 heme biosynthesis-associated TPR protein; Region: TPR_hemY_coli; TIGR00540 216591013166 HemY protein N-terminus; Region: HemY_N; pfam07219 216591013167 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591013168 TPR motif; other site 216591013169 binding surface 216591013170 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0039 216591013171 HMMPfam hit to PF07219, HemY protein N-terminus, score 8e-21 216591013172 2 probable transmembrane helices predicted for BCAL2628 by TMHMM2.0 at aa 5-27 and 42-64 216591013173 bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed; Region: PRK06975 216591013174 Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578 216591013175 active site 216591013176 putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920 216591013177 HMMPfam hit to PF04375, HemX, score 3.9e-56 216591013178 1 probable transmembrane helix predicted for BCAL2629 by TMHMM2.0 at aa 326-348 216591013179 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013180 HMMPfam hit to PF02602, Uroporphyrinogen-III synthase HemD, score 4.3e-07 216591013181 porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072 216591013182 Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494 216591013183 domain interfaces; other site 216591013184 active site 216591013185 HMMPfam hit to PF03900, Porphobilinogen deaminase, C-terminal, score 6.4e-15 216591013186 PS00533 Porphobilinogen deaminase cofactor-binding site. 216591013187 HMMPfam hit to PF01379, Porphobilinogen deaminase, dipyrometh, score 6.5e-120 216591013188 phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009 216591013189 Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352 216591013190 HMMPfam hit to PF00311, Phosphoenolpyruvate carboxylase, score 3.1e-88 216591013191 PS00781 Phosphoenolpyruvate carboxylase active site 1. 216591013192 PS00393 Phosphoenolpyruvate carboxylase active site 2. 216591013193 Methyltransferase domain; Region: Methyltransf_31; pfam13847 216591013194 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591013195 S-adenosylmethionine binding site [chemical binding]; other site 216591013196 HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 3e-07 216591013197 HMMPfam hit to PF08241, Methyltransferase domain, score 5.5e-30 216591013198 HMMPfam hit to PF08242, Methyltransferase domain, score 4.1e-19 216591013199 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591013200 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591013201 sequence-specific DNA binding site [nucleotide binding]; other site 216591013202 salt bridge; other site 216591013203 Predicted helix-turn-helix motif with score 1733.000, SD 5.09 at aa 49-70, sequence LRREEVAQLCGVSPTWYTWIEQ 216591013204 Spore Coat Protein U domain; Region: SCPU; pfam05229 216591013205 Uncharacterized secreted protein [Function unknown]; Region: COG5430 216591013206 HMMPfam hit to PF05229, Spore Coat Protein U domain, score 9.7e-20 216591013207 HMMPfam hit to PF05229, Spore Coat Protein U domain, score 3.7e-06 216591013208 1 probable transmembrane helix predicted for BCAL2634a by TMHMM2.0 at aa 12-31 216591013209 Uncharacterized secreted protein [Function unknown]; Region: COG5430 216591013210 2 probable transmembrane helices predicted for BCAL2635 by TMHMM2.0 at aa 9-31 and 46-68 216591013211 HMMPfam hit to PF05229, Spore Coat Protein U domain, score 3.8e-10 216591013212 P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121 216591013213 Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345 216591013214 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 216591013215 Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577 216591013216 PapC C-terminal domain; Region: PapC_C; pfam13953 216591013217 HMMPfam hit to PF00577, Fimbrial Usher protein, score 1.5e-11 216591013218 argininosuccinate lyase; Provisional; Region: PRK00855 216591013219 Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359 216591013220 active sites [active] 216591013221 tetramer interface [polypeptide binding]; other site 216591013222 HMMPfam hit to PF00206, Lyase, score 5e-89 216591013223 PS00163 Fumarate lyases signature. 216591013224 Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637 216591013225 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591013226 motif II; other site 216591013227 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.7e-28 216591013228 Protein of unknown function (DUF1311); Region: DUF1311; pfam07007 216591013229 Protein of unknown function (DUF1311); Region: DUF1311; cl01530 216591013230 1 probable transmembrane helix predicted for BCAL2640 by TMHMM2.0 at aa 13-35 216591013231 Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709 216591013232 Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982 216591013233 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 216591013234 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591013235 catalytic residue [active] 216591013236 Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711 216591013237 HMMPfam hit to PF03711, Orn/Lys/Arg decarboxylase, C-terminal doma, score 4e-73 216591013238 HMMPfam hit to PF01276, Orn/Lys/Arg decarboxylase, major domain, score 5.9e-192 216591013239 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013240 PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 216591013241 HMMPfam hit to PF03709, Orn/Lys/Arg decarboxylase, N-terminal doma, score 1.2e-41 216591013242 Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557 216591013243 trimer interface [polypeptide binding]; other site 216591013244 active site 216591013245 Copper/zinc superoxide dismutase (SODC); Region: Sod_Cu; pfam00080 216591013246 E-class dimer interface [polypeptide binding]; other site 216591013247 P-class dimer interface [polypeptide binding]; other site 216591013248 active site 216591013249 Cu2+ binding site [ion binding]; other site 216591013250 Zn2+ binding site [ion binding]; other site 216591013251 HMMPfam hit to PF00080, Copper/zinc superoxide dismutase (SODC), score 1.5e-11 216591013252 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013253 ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489 216591013254 MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037 216591013255 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 4.2e-14 216591013256 PS01215 Mrp family signature. 216591013257 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013258 HMMPfam hit to PF01883, Domain of unknown function DUF59, score 0.00015 216591013259 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 216591013260 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591013261 ligand binding site [chemical binding]; other site 216591013262 2 probable transmembrane helices predicted for BCAL2645 by TMHMM2.0 at aa 5-27 and 42-64 216591013263 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013264 HMMPfam hit to PF05433, Rickettsia 17 kDa surface antigen, score 1e-08 216591013265 HMMPfam hit to PF00691, OmpA family, score 5.8e-37 216591013266 methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133 216591013267 catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814 216591013268 active site 216591013269 HIGH motif; other site 216591013270 KMSKS motif; other site 216591013271 Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957 216591013272 tRNA binding surface [nucleotide binding]; other site 216591013273 anticodon binding site; other site 216591013274 tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins. This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties. MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800 216591013275 dimer interface [polypeptide binding]; other site 216591013276 putative tRNA-binding site [nucleotide binding]; other site 216591013277 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591013278 HMMPfam hit to PF01588, Putative tRNA binding domain, score 6.8e-36 216591013279 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911 216591013280 Family of unknown function (DUF490); Region: DUF490; pfam04357 216591013281 HMMPfam hit to PF04357, Family of unknown function (DUF490), score 9.8e-38 216591013282 1 probable transmembrane helix predicted for BCAL2647 by TMHMM2.0 at aa 36-58 216591013283 Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729 216591013284 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 216591013285 Surface antigen; Region: Bac_surface_Ag; pfam01103 216591013286 HMMPfam hit to PF01103, Surface antigen, score 6.5e-49 216591013287 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 5.8e-08 216591013288 Protein of unknown function (DUF3460); Region: DUF3460; pfam11943 216591013289 Rec8/ScpA/Scc1-like protein (kleisin family) [Replication, recombination, and repair]; Region: scpA; COG1354 216591013290 HMMPfam hit to PF02616, ScpA/B protein, score 3.5e-25 216591013291 pantoate--beta-alanine ligase; Region: panC; TIGR00018 216591013292 Pantoate-beta-alanine ligase; Region: PanC; cd00560 216591013293 active site 216591013294 ATP-binding site [chemical binding]; other site 216591013295 pantoate-binding site; other site 216591013296 HXXH motif; other site 216591013297 HMMPfam hit to PF02569, Pantoate-beta-alanine ligase, score 1.1e-107 216591013298 Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919 216591013299 tetramerization interface [polypeptide binding]; other site 216591013300 active site 216591013301 HMMPfam hit to PF02261, Aspartate decarboxylase, score 6.3e-77 216591013302 PS00678 Trp-Asp (WD) repeats signature. 216591013303 ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192 216591013304 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 216591013305 P-loop; other site 216591013306 Magnesium ion binding site [ion binding]; other site 216591013307 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 7.6e-21 216591013308 Predicted membrane protein [Function unknown]; Region: COG2259 216591013309 4 probable transmembrane helices predicted for BCAL2654 by TMHMM2.0 at aa 13-35, 45-67, 74-91 and 106-128 216591013310 HMMPfam hit to PF07681, DoxX, score 1e-34 216591013311 cobyric acid synthase; Provisional; Region: PRK00784 216591013312 dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090 216591013313 Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750 216591013314 catalytic triad [active] 216591013315 HMMPfam hit to PF07685, CobB/CobQ-like glutamine amidotransferase do, score 7.5e-70 216591013316 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 1.2e-52 216591013317 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013318 Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544 216591013319 homotrimer interface [polypeptide binding]; other site 216591013320 Walker A motif; other site 216591013321 GTP binding site [chemical binding]; other site 216591013322 Walker B motif; other site 216591013323 HMMPfam hit to PF02283, Cobinamide kinase / cobinamide phosphate gua, score 1.3e-61 216591013324 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013325 cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209 216591013326 HMMPfam hit to PF03186, CobD/Cbib protein, score 1.9e-81 216591013327 3 probable transmembrane helices predicted for BCAL2658 by TMHMM2.0 at aa 54-76, 154-176 and 288-310 216591013328 putative threonine-phosphate decarboxylase; Provisional; Region: PRK06959 216591013329 L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140 216591013330 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591013331 catalytic residue [active] 216591013332 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.6e-13 216591013333 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 216591013334 vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379 216591013335 Cobalamin binding protein BtuF. These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species. They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144 216591013336 cobalamin binding residues [chemical binding]; other site 216591013337 putative BtuC binding residues; other site 216591013338 dimer interface [polypeptide binding]; other site 216591013339 HMMPfam hit to PF01497, Periplasmic binding protein, score 9.9e-26 216591013340 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 216591013341 catalytic core [active] 216591013342 HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 1.5e-21 216591013343 cobalamin synthase; Reviewed; Region: cobS; PRK00235 216591013344 HMMPfam hit to PF02654, Cobalamin-5-phosphate synthase, score 2e-12 216591013345 6 probable transmembrane helices predicted for BCAL2662 by TMHMM2.0 at aa 7-29, 34-56, 63-80, 110-129, 176-193 and 197-214 216591013346 Phosphoribosyltransferase; Region: DBI_PRT; pfam02277 216591013347 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439 216591013348 putative dimer interface [polypeptide binding]; other site 216591013349 active site pocket [active] 216591013350 putative cataytic base [active] 216591013351 HMMPfam hit to PF02277, Phosphoribosyltransferase, score 2.1e-159 216591013352 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013353 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 216591013354 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 216591013355 Walker A/P-loop; other site 216591013356 ATP binding site [chemical binding]; other site 216591013357 Q-loop/lid; other site 216591013358 ABC transporter signature motif; other site 216591013359 Walker B; other site 216591013360 D-loop; other site 216591013361 H-loop/switch region; other site 216591013362 HMMPfam hit to PF00005, ABC transporter, score 2.8e-49 216591013363 PS00211 ABC transporters family signature. 216591013364 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013365 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 216591013366 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 216591013367 ABC-ATPase subunit interface; other site 216591013368 dimer interface [polypeptide binding]; other site 216591013369 putative PBP binding regions; other site 216591013370 HMMPfam hit to PF01032, FecCD transport family, score 3.9e-82 216591013371 8 probable transmembrane helices predicted for BCAL2665 by TMHMM2.0 at aa 12-34, 65-87, 94-116, 121-138, 150-172, 197-219, 240-262 and 304-326 216591013372 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013373 TATA element modulatory factor 1 TATA binding; Region: TMF_TATA_bd; pfam12325 216591013374 Cell division protein ZapA; Region: ZapA; pfam05164 216591013375 HMMPfam hit to PF05164, Cell division protein ZapA, score 2.8e-19 216591013376 EVE domain; Region: EVE; cl00728 216591013377 HMMPfam hit to PF04543, Family of unknown function (DUF589), score 1.5e-79 216591013378 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591013379 Protein of unknown function (DUF541); Region: SIMPL; cl01077 216591013380 1 probable transmembrane helix predicted for BCAL2669 by TMHMM2.0 at aa 7-29 216591013381 HMMPfam hit to PF04402, Protein of unknown function (DUF541), score 4.3e-20 216591013382 prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052 216591013383 HMMPfam hit to PF01790, Prolipoprotein diacylglyceryl transferase, score 3.8e-135 216591013384 5 probable transmembrane helices predicted for BCAL2670 by TMHMM2.0 at aa 17-39, 60-79, 94-116, 231-248 and 268-287 216591013385 PS01311 Prolipoprotein diacylglyceryl transferase signature. 216591013386 DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986 216591013387 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591013388 The C-terminal substrate binding domain of LysR-type transcriptional regulator, IlvR, involved in the biosynthesis of isoleucine, leucine and valine; contains type 2 periplasmic binding fold; Region: PBP2_IlvR; cd08453 216591013389 putative dimerization interface [polypeptide binding]; other site 216591013390 putative substrate binding pocket [chemical binding]; other site 216591013391 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.4e-45 216591013392 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.4e-20 216591013393 PS00044 Bacterial regulatory proteins, lysR family signature. 216591013394 Predicted helix-turn-helix motif with score 1485.000, SD 4.24 at aa 21-42, sequence RHFGRAAERLSMTQPPLSQAIR 216591013395 dihydroxy-acid dehydratase; Provisional; Region: PRK00911 216591013396 HMMPfam hit to PF00920, Dehydratase family, score 5.5e-283 216591013397 PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 216591013398 Cytochrome c; Region: Cytochrom_C; cl11414 216591013399 HMMPfam hit to PF00034, Cytochrome c, score 8.7e-09 216591013400 PS00190 Cytochrome c family heme-binding site signature. 216591013401 Protein of unknown function (DUF2486); Region: DUF2486; pfam10667 216591013402 DNA polymerase III chi subunit, HolC; Region: DNA_pol3_chi; pfam04364 216591013403 HMMPfam hit to PF04364, DNA polymerase III chi subunit, HolC, score 3.5e-28 216591013404 multifunctional aminopeptidase A; Provisional; Region: PRK00913 216591013405 Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433 216591013406 interface (dimer of trimers) [polypeptide binding]; other site 216591013407 Substrate-binding/catalytic site; other site 216591013408 Zn-binding sites [ion binding]; other site 216591013409 HMMPfam hit to PF00883, Cytosol aminopeptidase family, cataly, score 6.4e-184 216591013410 PS00631 Cytosol aminopeptidase signature. 216591013411 HMMPfam hit to PF02789, Cytosol aminopeptidase family, N-term, score 1.3e-31 216591013412 Predicted permeases [General function prediction only]; Region: COG0795 216591013413 Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739 216591013414 HMMPfam hit to PF03739, Predicted permease YjgP/YjgQ family, score 5.3e-48 216591013415 6 probable transmembrane helices predicted for BCAL2677 by TMHMM2.0 at aa 13-35, 50-72, 102-124, 264-286, 295-314 and 324-346 216591013416 Predicted permeases [General function prediction only]; Region: COG0795; cl12074 216591013417 Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739 216591013418 HMMPfam hit to PF03739, Predicted permease YjgP/YjgQ family, score 1.7e-46 216591013419 6 probable transmembrane helices predicted for BCAL2678 by TMHMM2.0 at aa 12-34, 61-83, 103-125, 299-318, 325-347 and 357-379 216591013420 Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]; Region: COG2138 216591013421 Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416 216591013422 putative active site [active] 216591013423 HMMPfam hit to PF01903, CbiX, score 2e-34 216591013424 Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642 216591013425 active site 216591013426 SAM binding site [chemical binding]; other site 216591013427 homodimer interface [polypeptide binding]; other site 216591013428 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 3.7e-62 216591013429 PS00840 Uroporphyrin-III C-methyltransferase signature 2. 216591013430 PS00839 Uroporphyrin-III C-methyltransferase signature 1. 216591013431 GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895 216591013432 CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166 216591013433 CysD dimerization site [polypeptide binding]; other site 216591013434 G1 box; other site 216591013435 putative GEF interaction site [polypeptide binding]; other site 216591013436 GTP/Mg2+ binding site [chemical binding]; other site 216591013437 Switch I region; other site 216591013438 G2 box; other site 216591013439 G3 box; other site 216591013440 Switch II region; other site 216591013441 G4 box; other site 216591013442 G5 box; other site 216591013443 CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695 216591013444 TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095 216591013445 HMMPfam hit to PF03144, Elongation factor Tu domain, score 1.2e-07 216591013446 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 3.5e-61 216591013447 PS00301 GTP-binding elongation factors signature. 216591013448 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013449 sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039 216591013450 This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713 216591013451 Active Sites [active] 216591013452 Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide; Region: AANH_like; cl00292 216591013453 HMMPfam hit to PF01507, Phosphoadenosine phosphosulfate reductase, score 7.3e-83 216591013454 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175 216591013455 This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713 216591013456 Active Sites [active] 216591013457 HMMPfam hit to PF01507, Phosphoadenosine phosphosulfate reductase, score 5.5e-48 216591013458 PS00079 Multicopper oxidases signature 1. 216591013459 Bacterial protein of unknown function (DUF934); Region: DUF934; pfam06073 216591013460 HMMPfam hit to PF06073, Bacterial protein of unknown function (DUF93, score 6.5e-74 216591013461 Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155 216591013462 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 216591013463 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 216591013464 HMMPfam hit to PF01077, Nitrite and sulphite reductase 4Fe-4S do, score 2.5e-11 216591013465 HMMPfam hit to PF03460, Nitrite/Sulfite reductase ferredoxin-lik, score 4.8e-12 216591013466 HMMPfam hit to PF01077, Nitrite and sulphite reductase 4Fe-4S do, score 1.7e-56 216591013467 HMMPfam hit to PF03460, Nitrite/Sulfite reductase ferredoxin-lik, score 1.1e-17 216591013468 transcriptional regulator CysB-like protein; Reviewed; Region: PRK12684 216591013469 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591013470 The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413 216591013471 substrate binding site [chemical binding]; other site 216591013472 dimerization interface [polypeptide binding]; other site 216591013473 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3e-17 216591013474 Predicted helix-turn-helix motif with score 1416.000, SD 4.01 at aa 17-38, sequence FNLTEAAKALYTSQPGVSKAII 216591013475 PS00044 Bacterial regulatory proteins, lysR family signature. 216591013476 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.6e-47 216591013477 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591013478 Type I periplasmic binding component of ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in uptake of amino acids; Region: PBP1_ABC-type_HAAT_like; cd06333 216591013479 putative ligand binding site [chemical binding]; other site 216591013480 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013481 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591013482 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591013483 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591013484 putative effector binding pocket; other site 216591013485 dimerization interface [polypeptide binding]; other site 216591013486 HMMPfam hit to PF03466, LysR substrate binding domain, score 9e-46 216591013487 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.3e-18 216591013488 PS00044 Bacterial regulatory proteins, lysR family signature. 216591013489 Predicted helix-turn-helix motif with score 1753.000, SD 5.16 at aa 21-42, sequence GTFARAGEAMGLTQPAVSRAVA 216591013490 short chain dehydrogenase; Provisional; Region: PRK12937 216591013491 tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs; Region: THN_reductase-like_SDR_c; cd05362 216591013492 NADP binding site [chemical binding]; other site 216591013493 homodimer interface [polypeptide binding]; other site 216591013494 active site 216591013495 substrate binding site [chemical binding]; other site 216591013496 HMMPfam hit to PF00106, short chain dehydrogenase, score 4.6e-36 216591013497 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 3e-05 216591013498 HMMPfam hit to PF07993, Male sterility protein, score 0.0049 216591013499 short chain dehydrogenase; Provisional; Region: PRK12937 216591013500 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374 216591013501 NADP binding site [chemical binding]; other site 216591013502 active site 216591013503 steroid binding site; other site 216591013504 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.3e-24 216591013505 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 0.00042 216591013506 HMMPfam hit to PF07993, Male sterility protein, score 0.00045 216591013507 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591013508 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 0.00016 216591013509 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591013510 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591013511 LysR substrate binding domain; Region: LysR_substrate; pfam03466 216591013512 dimerization interface [polypeptide binding]; other site 216591013513 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.7e-15 216591013514 Predicted helix-turn-helix motif with score 1310.000, SD 3.65 at aa 39-60, sequence RGFAPAAERLALTPSAVSGHIK 216591013515 PS00044 Bacterial regulatory proteins, lysR family signature. 216591013516 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.8e-27 216591013517 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591013518 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591013519 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472 216591013520 putative effector binding pocket; other site 216591013521 putative dimerization interface [polypeptide binding]; other site 216591013522 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.4e-38 216591013523 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.2e-15 216591013524 Predicted helix-turn-helix motif with score 1086.000, SD 2.89 at aa 17-38, sequence GSFIKAAHALDAPRATVSAAVQ 216591013525 short chain dehydrogenase; Provisional; Region: PRK12744 216591013526 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591013527 NAD(P) binding site [chemical binding]; other site 216591013528 active site 216591013529 HMMPfam hit to PF00106, short chain dehydrogenase, score 6.5e-17 216591013530 DinB superfamily; Region: DinB_2; pfam12867 216591013531 CopC domain; Region: CopC; pfam04234 216591013532 HMMPfam hit to PF04234, Copper resistance protein CopC, score 2.7e-28 216591013533 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187 216591013534 Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553 216591013535 active site 216591013536 uracil binding [chemical binding]; other site 216591013537 HMMPfam hit to PF01479, S4 domain, score 0.0042 216591013538 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 3.7e-18 216591013539 PS01149 Rsu family of pseudouridine synthase signature. 216591013540 2 probable transmembrane helices predicted for BCAL2698 by TMHMM2.0 at aa 7-29 and 39-61 216591013541 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 216591013542 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591013543 NAD(P) binding site [chemical binding]; other site 216591013544 active site 216591013545 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0002 216591013546 CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609 216591013547 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591013548 catalytic loop [active] 216591013549 iron binding site [ion binding]; other site 216591013550 NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189 216591013551 FAD binding pocket [chemical binding]; other site 216591013552 FAD binding motif [chemical binding]; other site 216591013553 phosphate binding motif [ion binding]; other site 216591013554 beta-alpha-beta structure motif; other site 216591013555 NAD binding pocket [chemical binding]; other site 216591013556 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 2.4e-18 216591013557 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591013558 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 2.3e-27 216591013559 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 1.9e-35 216591013560 acetylornithine transaminase protein; Provisional; Region: argD; PRK03715 216591013561 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591013562 inhibitor-cofactor binding pocket; inhibition site 216591013563 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591013564 catalytic residue [active] 216591013565 HMMPfam hit to PF00202, Aminotransferase class-III, score 1.7e-113 216591013566 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591013567 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 216591013568 putative acetyltransferase; Provisional; Region: PRK03624 216591013569 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591013570 Coenzyme A binding pocket [chemical binding]; other site 216591013571 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.1e-20 216591013572 Uncharacterized conserved protein (DUF2278); Region: DUF2278; pfam10042 216591013573 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591013574 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591013575 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591013576 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591013577 Predicted helix-turn-helix motif with score 1703.000, SD 4.99 at aa 20-41, sequence EAIRAVARTHGLSHSTVSQWYA 216591013578 putative transposase OrfB; Reviewed; Region: PHA02517 216591013579 HTH-like domain; Region: HTH_21; pfam13276 216591013580 Integrase core domain; Region: rve; pfam00665 216591013581 Integrase core domain; Region: rve_2; pfam13333 216591013582 HMMPfam hit to PF00665, Integrase core domain, score 5.1e-42 216591013583 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 216591013584 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 216591013585 Walker A/P-loop; other site 216591013586 ATP binding site [chemical binding]; other site 216591013587 Q-loop/lid; other site 216591013588 ABC transporter signature motif; other site 216591013589 Walker B; other site 216591013590 D-loop; other site 216591013591 H-loop/switch region; other site 216591013592 HMMPfam hit to PF00005, ABC transporter, score 5.3e-48 216591013593 PS00211 ABC transporters family signature. 216591013594 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013595 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 216591013596 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 216591013597 Walker A/P-loop; other site 216591013598 ATP binding site [chemical binding]; other site 216591013599 Q-loop/lid; other site 216591013600 ABC transporter signature motif; other site 216591013601 Walker B; other site 216591013602 D-loop; other site 216591013603 H-loop/switch region; other site 216591013604 HMMPfam hit to PF00005, ABC transporter, score 6.3e-55 216591013605 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013606 ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177 216591013607 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 216591013608 TM-ABC transporter signature motif; other site 216591013609 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.2e-36 216591013610 8 probable transmembrane helices predicted for BCAL2707 by TMHMM2.0 at aa 23-45, 55-74, 79-98, 113-135, 142-161, 205-224, 255-277 and 292-314 216591013611 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591013612 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 216591013613 TM-ABC transporter signature motif; other site 216591013614 7 probable transmembrane helices predicted for BCAL2708 by TMHMM2.0 at aa 13-35, 67-89, 102-124, 153-175, 203-225, 245-267 and 280-302 216591013615 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.8e-44 216591013616 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013617 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761 216591013618 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045 216591013619 HMMPfam hit to PF02401, LytB protein, score 1.5e-162 216591013620 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 216591013621 FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047 216591013622 HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomeras, score 2.9e-07 216591013623 hypothetical protein; Reviewed; Region: PRK00024 216591013624 Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071 216591013625 MPN+ (JAMM) motif; other site 216591013626 Zinc-binding site [ion binding]; other site 216591013627 HMMPfam hit to PF04002, RadC, DNA repair protein, score 4.6e-61 216591013628 PS01302 DNA repair protein radC family signature. 216591013629 50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359 216591013630 HMMPfam hit to PF00830, Ribosomal L28 family, score 1e-29 216591013631 50S ribosomal protein L33; Validated; Region: rpmG; PRK00595 216591013632 HMMPfam hit to PF00471, Ribosomal protein L33, score 2e-17 216591013633 PS00582 Ribosomal protein L33 signature. 216591013634 L-aspartate oxidase; Provisional; Region: PRK09077 216591013635 L-aspartate oxidase; Provisional; Region: PRK06175 216591013636 Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910 216591013637 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 7.6e-05 216591013638 HMMPfam hit to PF00890, FAD binding domain, score 2.1e-132 216591013639 HMMPfam hit to PF02910, Fumarate reductase/succinate dehydroge, score 2.2e-07 216591013640 nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK06978 216591013641 Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572 216591013642 dimerization interface [polypeptide binding]; other site 216591013643 active site 216591013644 HMMPfam hit to PF01729, Quinolinate phosphoribosyl transferase, C-t, score 1.9e-79 216591013645 HMMPfam hit to PF02749, Quinolinate phosphoribosyl transferase, N-t, score 2e-28 216591013646 quinolinate synthetase; Provisional; Region: PRK09375 216591013647 The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505 216591013648 Fatty acid desaturase; Region: FA_desaturase; pfam00487 216591013649 Di-iron ligands [ion binding]; other site 216591013650 Transposase; Region: DDE_Tnp_ISL3; pfam01610 216591013651 HMMPfam hit to PF00487, Fatty acid desaturase, score 1.8e-08 216591013652 3 probable transmembrane helices predicted for BCAL2719 by TMHMM2.0 at aa 18-40, 142-164 and 169-188 216591013653 Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668 216591013654 Mechanosensitive ion channel; Region: MS_channel; pfam00924 216591013655 HMMPfam hit to PF00924, Mechanosensitive ion channel, score 3.6e-52 216591013656 6 probable transmembrane helices predicted for BCAL2720 by TMHMM2.0 at aa 24-46, 67-86, 96-118, 131-153, 173-195 and 224-246 216591013657 ribosomal RNA small subunit methyltransferase RsmB; Region: rsmB; TIGR00563 216591013658 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591013659 HMMPfam hit to PF01189, NOL1/NOP2/sun family, score 2.6e-56 216591013660 phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647 216591013661 Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645 216591013662 active site 216591013663 substrate binding site [chemical binding]; other site 216591013664 cosubstrate binding site; other site 216591013665 catalytic site [active] 216591013666 HMMPfam hit to PF00551, Formyl transferase, score 6.2e-70 216591013667 bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627 216591013668 FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064 216591013669 active site 216591013670 Riboflavin kinase; Region: Flavokinase; smart00904 216591013671 HMMPfam hit to PF06574, FAD synthetase, score 4e-79 216591013672 HMMPfam hit to PF01467, Cytidylyltransferase, score 0.0085 216591013673 HMMPfam hit to PF01687, Riboflavin kinase, score 9.8e-38 216591013674 isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743 216591013675 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 216591013676 active site 216591013677 HIGH motif; other site 216591013678 nucleotide binding site [chemical binding]; other site 216591013679 catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818 216591013680 active site 216591013681 KMSKS motif; other site 216591013682 Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960 216591013683 tRNA binding surface [nucleotide binding]; other site 216591013684 anticodon binding site; other site 216591013685 Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827 216591013686 HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 4.4e-290 216591013687 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591013688 HMMPfam hit to PF08264, Anticodon-binding domain, score 8e-46 216591013689 HMMPfam hit to PF06827, Zinc finger found in FPG and IleRS, score 5.4e-14 216591013690 lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376 216591013691 5 probable transmembrane helices predicted for BCAL2725 by TMHMM2.0 at aa 4-26, 33-55, 70-92, 99-121 and 134-156 216591013692 HMMPfam hit to PF01252, Signal peptidase (SPase) II, score 4.2e-51 216591013693 PS00855 Signal peptidases II signature. 216591013694 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579 216591013695 Flavoprotein; Region: Flavoprotein; pfam02441 216591013696 DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127 216591013697 HMMPfam hit to PF02441, Flavoprotein, score 7.8e-43 216591013698 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013699 HMMPfam hit to PF04127, DNA / pantothenate metabolism flavoprote, score 3.7e-22 216591013700 Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557 216591013701 trimer interface [polypeptide binding]; other site 216591013702 active site 216591013703 HMMPfam hit to PF00692, dUTPase, score 3.2e-46 216591013704 Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4705 216591013705 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 216591013706 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 216591013707 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 216591013708 HMMPfam hit to PF03988, Repeat of Unknown Function (DUF347), score 6.2e-11 216591013709 7 probable transmembrane helices predicted for BCAL2728 by TMHMM2.0 at aa 28-50, 63-80, 90-112, 128-150, 154-176, 183-205 and 215-237 216591013710 HMMPfam hit to PF03988, Repeat of Unknown Function (DUF347), score 5.5e-09 216591013711 HMMPfam hit to PF03988, Repeat of Unknown Function (DUF347), score 8.5e-13 216591013712 Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113 216591013713 HMMPfam hit to PF00324, Amino acid permease, score 4.2e-98 216591013714 12 probable transmembrane helices predicted for BCAL2729 by TMHMM2.0 at aa 21-43, 47-69, 103-125, 135-157, 170-192, 207-229, 249-271, 286-308, 342-361, 366-385, 405-427 and 431-453 216591013715 PS00044 Bacterial regulatory proteins, lysR family signature. 216591013716 PS00218 Amino acid permeases signature. 216591013717 ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639 216591013718 Clp amino terminal domain; Region: Clp_N; pfam02861 216591013719 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591013720 Walker A motif; other site 216591013721 ATP binding site [chemical binding]; other site 216591013722 Walker B motif; other site 216591013723 arginine finger; other site 216591013724 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591013725 Walker A motif; other site 216591013726 ATP binding site [chemical binding]; other site 216591013727 Walker B motif; other site 216591013728 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 216591013729 HMMPfam hit to PF07724, ATPase family associated with various cellul, score 3.9e-91 216591013730 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 6.4e-09 216591013731 PS00871 Chaperonins clpA/B signature 2. 216591013732 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013733 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.1e-10 216591013734 PS00870 Chaperonins clpA/B signature 1. 216591013735 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013736 HMMPfam hit to PF02861, Clp amino terminal domain, score 1e-16 216591013737 Uncharacterized conserved protein [Function unknown]; Region: COG2127 216591013738 HMMPfam hit to PF02617, ATP-dependent Clp protease adaptor protein C, score 1.1e-49 216591013739 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 216591013740 DNA-binding site [nucleotide binding]; DNA binding site 216591013741 RNA-binding motif; other site 216591013742 HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 4.2e-42 216591013743 PS00352 'Cold-shock' DNA-binding domain signature. 216591013744 Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132 216591013745 Multicopper oxidase; Region: Cu-oxidase_3; pfam07732 216591013746 Multicopper oxidase; Region: Cu-oxidase_2; pfam07731 216591013747 HMMPfam hit to PF07731, Multicopper oxidase, score 5.6e-26 216591013748 PS00080 Multicopper oxidases signature 2. 216591013749 HMMPfam hit to PF07732, Multicopper oxidase, score 1.9e-41 216591013750 1 probable transmembrane helix predicted for BCAL2733 by TMHMM2.0 at aa 13-32 216591013751 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013752 Monomeric isocitrate dehydrogenase [Energy production and conversion]; Region: Icd; COG2838 216591013753 Monomeric isocitrate dehydrogenase; Region: IDH; cl15383 216591013754 HMMPfam hit to PF03971, Monomeric isocitrate dehydrogenase, score 0 216591013755 isocitrate dehydrogenase; Validated; Region: PRK07362 216591013756 isocitrate dehydrogenase; Reviewed; Region: PRK07006 216591013757 HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase, score 7.4e-153 216591013758 PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 216591013759 Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130 216591013760 pseudouridine synthase; Region: TIGR00093 216591013761 active site 216591013762 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 3.1e-23 216591013763 PS01149 Rsu family of pseudouridine synthase signature. 216591013764 Uncharacterized ACR, COG1430; Region: DUF192; pfam02643 216591013765 HMMPfam hit to PF02643, Uncharacterized ACR, COG1430, score 3.7e-39 216591013766 elongation factor G; Reviewed; Region: PRK00007 216591013767 Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886 216591013768 G1 box; other site 216591013769 putative GEF interaction site [polypeptide binding]; other site 216591013770 GTP/Mg2+ binding site [chemical binding]; other site 216591013771 Switch I region; other site 216591013772 G2 box; other site 216591013773 G3 box; other site 216591013774 Switch II region; other site 216591013775 G4 box; other site 216591013776 G5 box; other site 216591013777 EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088 216591013778 EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434 216591013779 EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G. Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713 216591013780 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.5e-109 216591013781 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013782 PS00301 GTP-binding elongation factors signature. 216591013783 HMMPfam hit to PF03144, Elongation factor Tu domain, score 7.2e-21 216591013784 HMMPfam hit to PF03764, Elongation factor G, domain IV, score 1.5e-68 216591013785 HMMPfam hit to PF00679, Elongation factor G C-terminus, score 2.9e-48 216591013786 High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376 216591013787 8 probable transmembrane helices predicted for BCAL2740 by TMHMM2.0 at aa 21-43, 48-65, 91-113, 128-150, 197-219, 224-246, 267-289 and 314-336 216591013788 HMMPfam hit to PF03824, High-affinity nickel-transport protein, score 1.7e-103 216591013789 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013790 1 probable transmembrane helix predicted for BCAL2741 by TMHMM2.0 at aa 10-32 216591013791 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591013792 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 216591013793 active site 216591013794 catalytic tetrad [active] 216591013795 HMMPfam hit to PF00248, Aldo/keto reductase family, score 9.5e-66 216591013796 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 216591013797 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591013798 DNA-binding site [nucleotide binding]; DNA binding site 216591013799 UTRA domain; Region: UTRA; pfam07702 216591013800 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 1.4e-19 216591013801 PS00043 Bacterial regulatory proteins, gntR family signature. 216591013802 Predicted helix-turn-helix motif with score 1092.000, SD 2.91 at aa 46-67, sequence PSERVLSEALGVSRITARKAIA 216591013803 HMMPfam hit to PF07702, UTRA domain, score 1.5e-48 216591013804 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591013805 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591013806 HMMPfam hit to PF02515, CoA-transferase family III, score 1.8e-09 216591013807 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 216591013808 MerR family regulatory protein; Region: MerR; pfam00376 216591013809 Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416 216591013810 Citrate synthase (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the oxidative citric acid cycle (TCA or Krebs cycle). Peroxisomal CS is involved in the glyoxylate...; Region: citrate_synt_like_2; cd06102 216591013811 Citrate synthase [Energy production and conversion]; Region: GltA; COG0372 216591013812 dimer interface [polypeptide binding]; other site 216591013813 active site 216591013814 oxalacetate/citrate binding site [chemical binding]; other site 216591013815 citrylCoA binding site [chemical binding]; other site 216591013816 coenzyme A binding site [chemical binding]; other site 216591013817 catalytic triad [active] 216591013818 Predicted helix-turn-helix motif with score 1732.000, SD 5.09 at aa 4-25, sequence LSAQEAAGMLGVSVSTLYAYVS 216591013819 HMMPfam hit to PF00376, MerR family regulatory protein, score 7.3e-09 216591013820 HMMPfam hit to PF00285, Citrate synthase, score 6.2e-14 216591013821 Protein of unknown function (DUF2917); Region: DUF2917; pfam11142 216591013822 PS00228 Tubulin-beta mRNA autoregulation signal. 216591013823 putative transporter; Provisional; Region: PRK10504 216591013824 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591013825 putative substrate translocation pore; other site 216591013826 14 probable transmembrane helices predicted for BCAL2748 by TMHMM2.0 at aa 17-39, 54-76, 83-105, 109-131, 143-165, 170-192, 205-222, 232-254, 261-283, 298-320, 333-355, 365-387, 400-422 and 437-459 216591013827 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.3e-57 216591013828 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013829 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013830 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 216591013831 HMMPfam hit to PF00563, EAL domain, score 4.9e-09 216591013832 tellurite resistance protein TehB; Provisional; Region: PRK11207 216591013833 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 216591013834 S-adenosylmethionine binding site [chemical binding]; other site 216591013835 HMMPfam hit to PF08241, Methyltransferase domain, score 5.3e-11 216591013836 HMMPfam hit to PF08242, Methyltransferase domain, score 4.4e-10 216591013837 2-dehydropantoate 2-reductase; Provisional; Region: PRK08229 216591013838 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 216591013839 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 216591013840 HMMPfam hit to PF08546, Ketopantoate reductase PanE/ApbA C ter, score 8.7e-34 216591013841 HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 5.8e-41 216591013842 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 1.1e-05 216591013843 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013844 Predicted membrane protein [Function unknown]; Region: COG4539 216591013845 5 probable transmembrane helices predicted for BCAL2752 by TMHMM2.0 at aa 35-54, 58-80, 87-106, 111-133 and 145-167 216591013846 HMMPfam hit to PF06127, Protein of unknown function (DUF962), score 1e-68 216591013847 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 216591013848 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 216591013849 ligand binding site [chemical binding]; other site 216591013850 flexible hinge region; other site 216591013851 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 216591013852 putative switch regulator; other site 216591013853 non-specific DNA interactions [nucleotide binding]; other site 216591013854 DNA binding site [nucleotide binding] 216591013855 sequence specific DNA binding site [nucleotide binding]; other site 216591013856 putative cAMP binding site [chemical binding]; other site 216591013857 HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 2.6e-25 216591013858 Predicted helix-turn-helix motif with score 1405.000, SD 3.97 at aa 180-201, sequence LSQETLASMLSLTRQTTNQLLK 216591013859 Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059 216591013860 chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937 216591013861 Chromate transporter; Region: Chromate_transp; pfam02417 216591013862 HMMPfam hit to PF02417, Chromate transporter, score 3.8e-17 216591013863 10 probable transmembrane helices predicted for BCAL2754 by TMHMM2.0 at aa 15-37, 83-105, 120-139, 160-182, 202-224, 236-258, 268-290, 299-321, 336-358 and 378-400 216591013864 HMMPfam hit to PF02417, Chromate transporter, score 5.7e-08 216591013865 putative transposase OrfB; Reviewed; Region: PHA02517 216591013866 Integrase core domain; Region: rve; pfam00665 216591013867 Integrase core domain; Region: rve_3; pfam13683 216591013868 HMMPfam hit to PF00665, Integrase core domain, score 1.1e-35 216591013869 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591013870 superoxide dismutase; Provisional; Region: PRK10543 216591013871 Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081 216591013872 Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777 216591013873 HMMPfam hit to PF02777, Iron/manganese superoxide dismutases, C-term, score 1.9e-72 216591013874 PS00088 Manganese and iron superoxide dismutases signature. 216591013875 HMMPfam hit to PF00081, Iron/manganese superoxide dismutases, alpha-, score 1.9e-49 216591013876 exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286 216591013877 ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489 216591013878 generic binding surface II; other site 216591013879 generic binding surface I; other site 216591013880 HMMPfam hit to PF02601, Exonuclease VII, large subunit, score 1.7e-41 216591013881 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 5.9e-13 216591013882 tetraacyldisaccharide 4'-kinase; Provisional; Region: PRK01906 216591013883 tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652 216591013884 HMMPfam hit to PF02606, Tetraacyldisaccharide-1-P 4'-kinase, score 3.6e-70 216591013885 Uncharacterized conserved protein [Function unknown]; Region: COG2835 216591013886 HMMPfam hit to PF03966, Trm112p-like protein, score 2.5e-26 216591013887 3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450 216591013888 CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517 216591013889 Ligand binding site; other site 216591013890 oligomer interface; other site 216591013891 HMMPfam hit to PF02348, Cytidylyltransferase, score 4e-71 216591013892 adenylate kinase; Reviewed; Region: adk; PRK00279 216591013893 Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428 216591013894 AMP-binding site [chemical binding]; other site 216591013895 ATP-AMP (Ap5A)-binding site [chemical binding]; other site 216591013896 HMMPfam hit to PF00406, Adenylate kinase, score 1.5e-92 216591013897 PS00113 Adenylate kinase signature. 216591013898 HMMPfam hit to PF05191, Adenylate kinase, active site lid, score 6.7e-22 216591013899 Uncharacterized conserved protein [Function unknown]; Region: COG2912 216591013900 Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369 216591013901 PS00030 Eukaryotic putative RNA-binding region RNP-1 signature. 216591013902 Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728 216591013903 MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123 216591013904 10 probable transmembrane helices predicted for BCAL2764 by TMHMM2.0 at aa 91-113, 128-150, 157-179, 184-203, 319-341, 356-378, 390-409, 414-433, 446-468 and 483-505 216591013905 PS00962 Ribosomal protein S2 signature 1. 216591013906 HMMPfam hit to PF03023, MviN-like protein, score 1.3e-153 216591013907 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591013908 30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239 216591013909 HMMPfam hit to PF01649, Ribosomal protein S20, score 3.5e-28 216591013910 Protein of unknown function (DUF3579); Region: DUF3579; pfam12112 216591013911 ornithine carbamoyltransferase; Provisional; Region: PRK00779 216591013912 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 216591013913 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 216591013914 HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, ca, score 8.3e-65 216591013915 PS00097 Aspartate and ornithine carbamoyltransferases signature. 216591013916 HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, As, score 1e-52 216591013917 UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046 216591013918 FAD binding domain; Region: FAD_binding_4; pfam01565 216591013919 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873 216591013920 HMMPfam hit to PF02873, UDP-N-acetylenolpyruvoylglucosamine red, score 2.6e-45 216591013921 HMMPfam hit to PF01565, FAD binding domain, score 7.3e-18 216591013922 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666 216591013923 Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740 216591013924 HMMPfam hit to PF04461, Protein of unknown function (DUF520), score 2.3e-70 216591013925 putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220 216591013926 HMMPfam hit to PF02660, Domain of unknown function DUF, score 9.4e-61 216591013927 4 probable transmembrane helices predicted for BCAL2770 by TMHMM2.0 at aa 7-29, 79-100, 113-135 and 155-177 216591013928 This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002 216591013929 putative deacylase active site [active] 216591013930 HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associated do, score 7e-39 216591013931 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591013932 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06187 216591013933 acyl-activating enzyme (AAE) consensus motif; other site 216591013934 AMP binding site [chemical binding]; other site 216591013935 active site 216591013936 CoA binding site [chemical binding]; other site 216591013937 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.7e-117 216591013938 PS00904 Protein prenyltransferases alpha subunit repeat signature. 216591013939 PS00455 Putative AMP-binding domain signature. 216591013940 site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283 216591013941 XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798 216591013942 active site 216591013943 Int/Topo IB signature motif; other site 216591013944 HMMPfam hit to PF00589, Phage integrase family, score 1.3e-55 216591013945 Predicted helix-turn-helix motif with score 1027.000, SD 2.68 at aa 248-269, sequence RHAQQADVRAHLSPHTLRHAFA 216591013946 HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like, score 7.6e-19 216591013947 Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350 216591013948 The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445 216591013949 DNA binding site [nucleotide binding] 216591013950 active site 216591013951 HMMPfam hit to PF01035, 6-O-methylguanine DNA methyltransferase, score 2.8e-33 216591013952 PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 216591013953 Predicted helix-turn-helix motif with score 1075.000, SD 2.85 at aa 88-109, sequence LTYGQVAKRIGSAPRAVGQACG 216591013954 epoxyqueuosine reductase; Region: TIGR00276 216591013955 Domain of unknown function (DUF1730); Region: DUF1730; pfam08331 216591013956 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00047 216591013957 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591013958 HMMPfam hit to PF08331, Domain of unknown function (DUF1730), score 2.6e-26 216591013959 Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520 216591013960 HMMPfam hit to PF02367, Uncharacterised P-loop hydrolase UPF0079, score 1.7e-36 216591013961 PS00017 ATP/GTP-binding site motif A (P-loop). 216591013962 AMIN domain; Region: AMIN; pfam11741 216591013963 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 216591013964 active site 216591013965 metal binding site [ion binding]; metal-binding site 216591013966 HMMPfam hit to PF01520, N-acetylmuramoyl-L-alanine amidase, score 1.1e-85 216591013967 O-acetylserine/cysteine export protein; Provisional; Region: PRK11453 216591013968 EamA-like transporter family; Region: EamA; pfam00892 216591013969 10 probable transmembrane helices predicted for BCAL2778 by TMHMM2.0 at aa 7-29, 34-51, 60-82, 87-109, 116-133, 137-159, 168-190, 205-227, 234-256 and 261-283 216591013970 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 5e-17 216591013971 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.6e-13 216591013972 Pirin-related protein [General function prediction only]; Region: COG1741 216591013973 Pirin; Region: Pirin; pfam02678 216591013974 Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726 216591013975 HMMPfam hit to PF02678, Pirin, score 4.8e-58 216591013976 HMMPfam hit to PF05726, Pirin C-terminal cupin domain, score 2.1e-29 216591013977 Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118 216591013978 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 216591013979 catalytic residues [active] 216591013980 HMMPfam hit to PF00085, Thioredoxin, score 1.7e-26 216591013981 PS00194 Thioredoxin family active site. 216591013982 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0024 216591013983 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179 216591013984 Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755 216591013985 putative ATP binding site [chemical binding]; other site 216591013986 putative substrate interface [chemical binding]; other site 216591013987 HMMPfam hit to PF00899, ThiF family, score 5.7e-50 216591013988 pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558 216591013989 Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243 216591013990 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590 216591013991 HMMPfam hit to PF01243, Pyridoxamine 5'-phosphate oxidase, score 1.7e-35 216591013992 PS01064 Pyridoxamine 5'-phosphate oxidase signature. 216591013993 Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230 216591013994 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591013995 S-adenosylmethionine binding site [chemical binding]; other site 216591013996 HMMPfam hit to PF02353, Cyclopropane-fatty-acyl-phospholipid, score 3.7e-131 216591013997 HMMPfam hit to PF08241, Methyltransferase domain, score 2e-11 216591013998 HMMPfam hit to PF08242, Methyltransferase domain, score 1.3e-11 216591013999 Protein of unknown function DUF72; Region: DUF72; pfam01904 216591014000 HMMPfam hit to PF01904, Protein of unknown function DUF72, score 8e-24 216591014001 methionine sulfoxide reductase A; Provisional; Region: PRK14054 216591014002 HMMPfam hit to PF01625, Peptide methionine sulfoxide reductase, score 3.9e-83 216591014003 56kDa selenium binding protein (SBP56); Region: SBP56; pfam05694 216591014004 HMMPfam hit to PF05694, 56kDa selenium binding protein (SBP56), score 1.8e-206 216591014005 5 probable transmembrane helices predicted for BCAL2787 by TMHMM2.0 at aa 17-39, 49-71, 92-114, 134-156 and 169-191 216591014006 Flavin reductase like domain; Region: Flavin_Reduct; smart00903 216591014007 HMMPfam hit to PF01613, Flavin reductase like domain, score 1.3e-54 216591014008 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591014009 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591014010 putative DNA binding site [nucleotide binding]; other site 216591014011 putative Zn2+ binding site [ion binding]; other site 216591014012 AsnC family; Region: AsnC_trans_reg; pfam01037 216591014013 HMMPfam hit to PF01037, AsnC family, score 1.1e-26 216591014014 arylformamidase; Region: trp_arylform; TIGR03035 216591014015 HMMPfam hit to PF04199, Putative cyclase, score 2.2e-54 216591014016 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591014017 kynureninase; Region: kynureninase; TIGR01814 216591014018 Kynureninase [Amino acid transport and metabolism]; Region: COG3844 216591014019 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591014020 catalytic residue [active] 216591014021 HMMPfam hit to PF00266, Aminotransferase class-V, score 9.3e-08 216591014022 tryptophan 2,3-dioxygenase; Region: trp_2_3_diox; TIGR03036 216591014023 HMMPfam hit to PF03301, Tryptophan 2,3-dioxygenase, score 1.6e-101 216591014024 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591014025 benzoate transport; Region: 2A0115; TIGR00895 216591014026 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591014027 putative substrate translocation pore; other site 216591014028 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591014029 putative substrate translocation pore; other site 216591014030 HMMPfam hit to PF00083, Sugar (and other) transporter, score 2.4e-07 216591014031 12 probable transmembrane helices predicted for BCAL2793 by TMHMM2.0 at aa 40-62, 75-97, 106-125, 130-152, 165-187, 192-214, 276-298, 313-332, 339-358, 368-390, 402-424 and 428-450 216591014032 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.7e-44 216591014033 PS00216 Sugar transport proteins signature 1. 216591014034 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014035 2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522 216591014036 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 216591014037 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 216591014038 HMMPfam hit to PF08546, Ketopantoate reductase PanE/ApbA C terminal, score 7.6e-50 216591014039 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014040 HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 2.8e-49 216591014041 NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012 216591014042 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 216591014043 NAD(P) binding site [chemical binding]; other site 216591014044 catalytic residues [active] 216591014045 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.9e-179 216591014046 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591014047 benzoylformate decarboxylase; Reviewed; Region: PRK07092 216591014048 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 216591014049 PYR/PP interface [polypeptide binding]; other site 216591014050 dimer interface [polypeptide binding]; other site 216591014051 TPP binding site [chemical binding]; other site 216591014052 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591014053 Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of...; Region: TPP_BFDC; cd02002 216591014054 TPP-binding site [chemical binding]; other site 216591014055 dimer interface [polypeptide binding]; other site 216591014056 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 6.1e-33 216591014057 PS00187 Thiamine pyrophosphate enzymes signature. 216591014058 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 3.3e-07 216591014059 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 3.3e-50 216591014060 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591014061 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591014062 The C-terminal substrate binding domain of galactose-binding protein regulator contains the type 2 periplasmic binding fold; Region: PBP2_GbpR; cd08435 216591014063 putative dimerization interface [polypeptide binding]; other site 216591014064 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3e-25 216591014065 Predicted helix-turn-helix motif with score 1976.000, SD 5.92 at aa 18-39, sequence GSLGRAADALHVTQPALSRILK 216591014066 PS00044 Bacterial regulatory proteins, lysR family signature. 216591014067 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.3e-31 216591014068 Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246 216591014069 Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232 216591014070 Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125 216591014071 HMMPfam hit to PF01232, Mannitol dehydrogenase Rossmann domain, score 4e-50 216591014072 HMMPfam hit to PF08125, Mannitol dehydrogenase C-terminal domai, score 3.2e-89 216591014073 Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808 216591014074 N- and C-terminal domain interface [polypeptide binding]; other site 216591014075 D-xylulose kinase; Region: XylB; TIGR01312 216591014076 active site 216591014077 MgATP binding site [chemical binding]; other site 216591014078 catalytic site [active] 216591014079 metal binding site [ion binding]; metal-binding site 216591014080 xylulose binding site [chemical binding]; other site 216591014081 homodimer interface [polypeptide binding]; other site 216591014082 HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 2.2e-92 216591014083 PS00933 FGGY family of carbohydrate kinases signature 1. 216591014084 HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 3.4e-58 216591014085 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014086 PS00445 FGGY family of carbohydrate kinases signature 2. 216591014087 Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390 216591014088 Putative sugar-binding domain; Region: Sugar-bind; pfam04198 216591014089 Predicted helix-turn-helix motif with score 1214.000, SD 3.32 at aa 23-44, sequence DTQNEIAEKLQVSRPVAQRLVA 216591014090 HMMPfam hit to PF04198, Putative sugar-binding domain, score 6.6e-65 216591014091 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591014092 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591014093 putative substrate translocation pore; other site 216591014094 12 probable transmembrane helices predicted for BCAL2801 by TMHMM2.0 at aa 13-35, 50-72, 84-106, 111-128, 140-162, 166-188, 217-239, 249-271, 278-300, 304-326, 338-357 and 361-380 216591014095 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5e-39 216591014096 Beta-lactamase; Region: Beta-lactamase; pfam00144 216591014097 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 216591014098 HMMPfam hit to PF00144, Beta-lactamase, score 4.1e-74 216591014099 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591014100 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591014101 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_7; cd08476 216591014102 putative effector binding pocket; other site 216591014103 putative dimerization interface [polypeptide binding]; other site 216591014104 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.5e-16 216591014105 Predicted helix-turn-helix motif with score 1127.000, SD 3.03 at aa 17-38, sequence RSFVAAGRALGLSASAIGKRIA 216591014106 PS00044 Bacterial regulatory proteins, lysR family signature. 216591014107 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.9e-56 216591014108 maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000 216591014109 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 216591014110 Walker A/P-loop; other site 216591014111 ATP binding site [chemical binding]; other site 216591014112 Q-loop/lid; other site 216591014113 ABC transporter signature motif; other site 216591014114 Walker B; other site 216591014115 D-loop; other site 216591014116 H-loop/switch region; other site 216591014117 TOBE domain; Region: TOBE; pfam03459 216591014118 TOBE domain; Region: TOBE_2; pfam08402 216591014119 HMMPfam hit to PF08402, TOBE domain, score 1e-09 216591014120 HMMPfam hit to PF03459, TOBE domain, score 1.1e-09 216591014121 HMMPfam hit to PF00005, ABC transporter, score 4.4e-57 216591014122 PS00211 ABC transporters family signature. 216591014123 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014124 Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637 216591014125 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 4e-24 216591014126 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 216591014127 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591014128 dimer interface [polypeptide binding]; other site 216591014129 conserved gate region; other site 216591014130 putative PBP binding loops; other site 216591014131 ABC-ATPase subunit interface; other site 216591014132 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 9.4e-15 216591014133 6 probable transmembrane helices predicted for BCAL2806 by TMHMM2.0 at aa 21-43, 76-98, 115-137, 152-171, 192-214 and 246-268 216591014134 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591014135 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591014136 dimer interface [polypeptide binding]; other site 216591014137 conserved gate region; other site 216591014138 putative PBP binding loops; other site 216591014139 ABC-ATPase subunit interface; other site 216591014140 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3.1e-14 216591014141 6 probable transmembrane helices predicted for BCAL2807 by TMHMM2.0 at aa 35-57, 95-117, 124-146, 176-198, 234-256 and 282-304 216591014142 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591014143 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 216591014144 Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416 216591014145 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 1.6e-44 216591014146 1 probable transmembrane helix predicted for BCAL2808 by TMHMM2.0 at aa 13-35 216591014147 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014148 Tagatose 6 phosphate kinase; Region: Tagatose_6_P_K; pfam08013 216591014149 HMMPfam hit to PF08013, Tagatose 6 phosphate kinase, score 7.9e-229 216591014150 Predicted helix-turn-helix motif with score 1112.000, SD 2.97 at aa 360-381, sequence ETAQRLARQFSYSDRIRYYWLQ 216591014151 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166 216591014152 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 216591014153 substrate binding site [chemical binding]; other site 216591014154 ATP binding site [chemical binding]; other site 216591014155 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 2.2e-38 216591014156 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014157 sorbitol dehydrogenase; Provisional; Region: PRK07067 216591014158 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591014159 NAD(P) binding site [chemical binding]; other site 216591014160 active site 216591014161 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.5e-32 216591014162 PS00061 Short-chain dehydrogenases/reductases family signature. 216591014163 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591014164 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 216591014165 metal binding site 2 [ion binding]; metal-binding site 216591014166 putative DNA binding helix; other site 216591014167 metal binding site 1 [ion binding]; metal-binding site 216591014168 dimer interface [polypeptide binding]; other site 216591014169 structural Zn2+ binding site [ion binding]; other site 216591014170 HMMPfam hit to PF01475, Ferric uptake regulator family, score 2.3e-05 216591014171 Metal binding protein TroA_b. These proteins are predicted to function as initial receptors in ABC transport of metal ions. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: TroA_b; cd01020 216591014172 Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297 216591014173 metal binding site [ion binding]; metal-binding site 216591014174 HMMPfam hit to PF01297, Periplasmic solute binding protein family, score 7.3e-14 216591014175 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 216591014176 ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235 216591014177 HMMPfam hit to PF00005, ABC transporter, score 9.3e-47 216591014178 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014179 PS00211 ABC transporters family signature. 216591014180 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462 216591014181 ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108 216591014182 ABC-ATPase subunit interface; other site 216591014183 dimer interface [polypeptide binding]; other site 216591014184 HMMPfam hit to PF00950, ABC 3 transport family, score 6.2e-37 216591014185 7 probable transmembrane helices predicted for BCAL2815 by TMHMM2.0 at aa 5-24, 37-59, 79-101, 122-144, 166-188, 208-230 and 234-251 216591014186 Predicted helix-turn-helix motif with score 1107.000, SD 2.96 at aa 147-168, sequence SLQPELAEAKGVSLRTVSMLFL 216591014187 S-formylglutathione hydrolase; Region: PLN02442 216591014188 S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821 216591014189 HMMPfam hit to PF00756, Putative esterase, score 1e-80 216591014190 Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062 216591014191 class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300 216591014192 substrate binding site [chemical binding]; other site 216591014193 catalytic Zn binding site [ion binding]; other site 216591014194 NAD binding site [chemical binding]; other site 216591014195 structural Zn binding site [ion binding]; other site 216591014196 dimer interface [polypeptide binding]; other site 216591014197 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.9e-38 216591014198 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 5.1e-34 216591014199 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591014200 Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070 216591014201 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 216591014202 nucleotide binding site [chemical binding]; other site 216591014203 HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 6.2e-18 216591014204 HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 1.8e-59 216591014205 xanthine permease; Region: pbuX; TIGR03173 216591014206 HMMPfam hit to PF00860, Permease family, score 5.1e-139 216591014207 11 probable transmembrane helices predicted for BCAL2819 by TMHMM2.0 at aa 46-68, 75-97, 127-149, 156-178, 193-210, 215-237, 268-290, 343-365, 370-389, 402-424 and 434-456 216591014208 HMMPfam hit to PF00916, Sulfate transporter family, score 0.0039 216591014209 PS01116 Xanthine/uracil permeases family signature. 216591014210 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591014211 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.2e-50 216591014212 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.5e-46 216591014213 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014214 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915 216591014215 Protein export membrane protein; Region: SecD_SecF; cl14618 216591014216 Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456 216591014217 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 216591014218 12 probable transmembrane helices predicted for BCAL2821 by TMHMM2.0 at aa 9-31, 340-359, 366-388, 392-414, 438-460, 470-492, 540-559, 869-891, 898-920, 925-947, 968-990 and 1000-1022 216591014219 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014220 multidrug efflux system transporter AcrA; Provisional; Region: PRK15030 216591014221 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591014222 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591014223 HMMPfam hit to PF00529, HlyD family secretion protein, score 5.1e-59 216591014224 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014225 DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668 216591014226 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591014227 MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361 216591014228 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 9.6e-22 216591014229 PS01081 Bacterial regulatory proteins, tetR family signature. 216591014230 Predicted helix-turn-helix motif with score 2122.000, SD 6.41 at aa 32-53, sequence TSLADIAQHAGVTRGAIYWHFA 216591014231 HMMPfam hit to PF08361, MAATS-type transcriptional repressor, C-term, score 6.1e-19 216591014232 Isochorismatase family; Region: Isochorismatase; pfam00857 216591014233 Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014 216591014234 catalytic triad [active] 216591014235 conserved cis-peptide bond; other site 216591014236 HMMPfam hit to PF00857, Isochorismatase family, score 6.7e-10 216591014237 transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393 216591014238 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 216591014239 conserved cys residue [active] 216591014240 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591014241 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591014242 HMMPfam hit to PF01965, DJ-1/PfpI family, score 5.9e-13 216591014243 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.4e-06 216591014244 Predicted helix-turn-helix motif with score 1271.000, SD 3.52 at aa 239-260, sequence HSVDSLAERVLMSRRTFTRHFR 216591014245 PS00041 Bacterial regulatory proteins, araC family signature. 216591014246 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 3.7e-07 216591014247 Predicted helix-turn-helix motif with score 1271.000, SD 3.52 at aa 304-325, sequence SLRQHFAGALGTSPSAYRREFR 216591014248 START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643 216591014249 hydrophobic ligand binding site; other site 216591014250 1 probable transmembrane helix predicted for BCAL2826a by TMHMM2.0 at aa 212-234 216591014251 HMMPfam hit to PF06240, Carbon monoxide dehydrogenase subunit G (Cox, score 8.4e-06 216591014252 Domain of unknown function (DUF427); Region: DUF427; pfam04248 216591014253 HMMPfam hit to PF04248, Domain of unknown function (DUF427), score 4.3e-26 216591014254 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 216591014255 1 probable transmembrane helix predicted for BCAL2828 by TMHMM2.0 at aa 16-38 216591014256 periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037 216591014257 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 216591014258 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 216591014259 protein binding site [polypeptide binding]; other site 216591014260 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 216591014261 protein binding site [polypeptide binding]; other site 216591014262 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 3.9e-11 216591014263 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 7.8e-15 216591014264 HMMPfam hit to PF00089, Trypsin, score 8.7e-17 216591014265 1 probable transmembrane helix predicted for BCAL2829 by TMHMM2.0 at aa 5-27 216591014266 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591014267 dimer interface [polypeptide binding]; other site 216591014268 phosphorylation site [posttranslational modification] 216591014269 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591014270 ATP binding site [chemical binding]; other site 216591014271 Mg2+ binding site [ion binding]; other site 216591014272 G-X-G motif; other site 216591014273 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.9e-32 216591014274 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.5e-15 216591014275 HMMPfam hit to PF00672, HAMP domain, score 1.8e-05 216591014276 1 probable transmembrane helix predicted for BCAL2830 by TMHMM2.0 at aa 7-29 216591014277 DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643 216591014278 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591014279 active site 216591014280 phosphorylation site [posttranslational modification] 216591014281 intermolecular recognition site; other site 216591014282 dimerization interface [polypeptide binding]; other site 216591014283 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591014284 DNA binding site [nucleotide binding] 216591014285 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 4.3e-22 216591014286 HMMPfam hit to PF00072, Response regulator receiver domain, score 5.4e-42 216591014287 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane]; Region: DacB; COG2027 216591014288 HMMPfam hit to PF02113, D-Ala-D-Ala carboxypeptidase 3 (S13) fa, score 4.8e-74 216591014289 Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000 216591014290 Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116 216591014291 5 probable transmembrane helices predicted for BCAL2833 by TMHMM2.0 at aa 7-29, 49-71, 83-100, 133-152 and 157-176 216591014292 Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: Triacylglycerol_lipase_like; cd01847 216591014293 active site 216591014294 catalytic triad [active] 216591014295 oxyanion hole [active] 216591014296 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014297 Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009 216591014298 Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481 216591014299 HMMPfam hit to PF03481, SUA5 domain, score 1.2e-10 216591014300 HMMPfam hit to PF01300, yrdC domain, score 1e-50 216591014301 PS01147 SUA5/yciO/yrdC family signature. 216591014302 phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019 216591014303 ATP-grasp domain; Region: ATP-grasp; pfam02222 216591014304 HMMPfam hit to PF02222, ATP-grasp domain, score 6.5e-67 216591014305 HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase, ATP-g, score 0.002 216591014306 AIR carboxylase; Region: AIRC; pfam00731 216591014307 HMMPfam hit to PF00731, AIR carboxylase, score 4.8e-81 216591014308 phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362 216591014309 non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414 216591014310 ATP binding site [chemical binding]; other site 216591014311 active site 216591014312 substrate binding site [chemical binding]; other site 216591014313 HMMPfam hit to PF01259, SAICAR synthetase, score 1.8e-127 216591014314 PS01058 SAICAR synthetase signature 2. 216591014315 fructose-bisphosphate aldolase; Provisional; Region: PRK09197 216591014316 Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947 216591014317 intersubunit interface [polypeptide binding]; other site 216591014318 active site 216591014319 zinc binding site [ion binding]; other site 216591014320 Na+ binding site [ion binding]; other site 216591014321 HMMPfam hit to PF01116, Fructose-bisphosphate aldolase class-II, score 1.6e-167 216591014322 PS00806 Fructose-bisphosphate aldolase class-II signature 2. 216591014323 PS00602 Fructose-bisphosphate aldolase class-II signature 1. 216591014324 pyruvate kinase; Provisional; Region: PRK05826 216591014325 Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342 216591014326 domain interfaces; other site 216591014327 active site 216591014328 HMMPfam hit to PF02887, Pyruvate kinase, alpha/beta domain, score 5.5e-32 216591014329 HMMPfam hit to PF00224, Pyruvate kinase, barrel domain, score 2.9e-146 216591014330 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014331 Phosphoglycerate kinase; Region: PGK; pfam00162 216591014332 Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318 216591014333 substrate binding site [chemical binding]; other site 216591014334 hinge regions; other site 216591014335 ADP binding site [chemical binding]; other site 216591014336 catalytic site [active] 216591014337 HMMPfam hit to PF00162, Phosphoglycerate kinase, score 9.4e-145 216591014338 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014339 PS00111 Phosphoglycerate kinase signature. 216591014340 Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437 216591014341 3 probable transmembrane helices predicted for BCAL2842 by TMHMM2.0 at aa 6-25, 46-68 and 83-105 216591014342 HMMPfam hit to PF05437, Branched-chain amino acid transport protein, score 1.3e-30 216591014343 AzlC protein; Region: AzlC; cl00570 216591014344 6 probable transmembrane helices predicted for BCAL2843 by TMHMM2.0 at aa 20-38, 53-75, 88-110, 147-169, 176-198 and 213-232 216591014345 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014346 HMMPfam hit to PF03591, AzlC protein, score 1.1e-47 216591014347 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115 216591014348 BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557 216591014349 homodimer interface [polypeptide binding]; other site 216591014350 substrate-cofactor binding pocket; other site 216591014351 catalytic residue [active] 216591014352 HMMPfam hit to PF01063, Aminotransferase class IV, score 3.9e-106 216591014353 PS00770 Aminotransferases class-IV signature. 216591014354 Duplicated region 216591014355 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591014356 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591014357 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591014358 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591014359 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014360 HMMPfam hit to PF01548, Transposase, score 2.9e-12 216591014361 GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956 216591014362 PS01320 Uncharacterized protein family UPF0067 signature. 216591014363 Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086 216591014364 active site 216591014365 HMMPfam hit to PF00557, metallopeptidase family M24, score 1.1e-84 216591014366 PS00680 Methionine aminopeptidase subfamily 1 signature. 216591014367 PS00215 Mitochondrial energy transfer proteins signature. 216591014368 Protein of unknown function (DUF3423); Region: DUF3423; pfam11903 216591014369 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591014370 sequence-specific DNA binding site [nucleotide binding]; other site 216591014371 salt bridge; other site 216591014372 Cupin domain; Region: Cupin_2; cl17218 216591014373 HMMPfam hit to PF01381, Helix-turn-helix, score 2.6e-11 216591014374 Predicted helix-turn-helix motif with score 1253.000, SD 3.45 at aa 31-52, sequence YTLDTLAARSGVSRSMISLIER 216591014375 HMMPfam hit to PF07883, Cupin domain, score 0.0031 216591014376 Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247 216591014377 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.6e-15 216591014378 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591014379 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 2.5e-06 216591014380 Cache domain; Region: Cache_1; pfam02743 216591014381 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591014382 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591014383 metal binding site [ion binding]; metal-binding site 216591014384 active site 216591014385 I-site; other site 216591014386 HMMPfam hit to PF00990, GGDEF domain, score 5.9e-75 216591014387 2 probable transmembrane helices predicted for BCAL2852 by TMHMM2.0 at aa 6-28 and 288-310 216591014388 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014389 CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453 216591014390 HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 6.3e-39 216591014391 5 probable transmembrane helices predicted for BCAL2853 by TMHMM2.0 at aa 5-27, 34-53, 80-102, 135-157 and 161-180 216591014392 PS00379 CDP-alcohol phosphatidyltransferases signature. 216591014393 CDS is interrupted by an IS element insertion after codon 126. Similar to Burkholderia pseudomallei (Pseudomonas pseudomallei) putative excinuclease ABC subunit C UniProt:Q63SA4 (EMBL:BX571965) (745 aa) fasta scores: E()=9e-108, 78.331% id in 743 aa 216591014394 HMMPfam hit to PF08459, UvrC Helix-hairpin-helix N-terminal, score 6.3e-78 216591014395 HMMPfam hit to PF02151, UvrB/uvrC motif, score 1.2e-07 216591014396 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591014397 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591014398 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591014399 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591014400 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014401 HMMPfam hit to PF01548, Transposase, score 2.9e-12 216591014402 HMMPfam hit to PF01541, GIY-YIG catalytic domain, score 3.9e-28 216591014403 Uncharacterized protein conserved in bacteria (DUF2331); Region: DUF2331; pfam10093 216591014404 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4394 216591014405 elongation factor P; Validated; Region: PRK00529 216591014406 Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207 216591014407 S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470 216591014408 RNA binding site [nucleotide binding]; other site 216591014409 S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794 216591014410 RNA binding site [nucleotide binding]; other site 216591014411 HMMPfam hit to PF08207, Elongation factor P (EF-P) KOW-like domain, score 3.1e-05 216591014412 HMMPfam hit to PF01132, Elongation factor P (EF-P) OB domain, score 2.4e-12 216591014413 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 216591014414 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591014415 active site 216591014416 phosphorylation site [posttranslational modification] 216591014417 intermolecular recognition site; other site 216591014418 dimerization interface [polypeptide binding]; other site 216591014419 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591014420 Walker A motif; other site 216591014421 ATP binding site [chemical binding]; other site 216591014422 Walker B motif; other site 216591014423 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591014424 HMMPfam hit to PF00072, Response regulator receiver domain, score 7e-34 216591014425 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 4.1e-69 216591014426 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 1.6e-12 216591014427 Predicted helix-turn-helix motif with score 1795.000, SD 5.30 at aa 435-456, sequence GTRHRAATLLGISPKTLYNKLQ 216591014428 Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472 216591014429 beta-hexosaminidase; Provisional; Region: PRK05337 216591014430 HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N terminal, score 2.6e-32 216591014431 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591014432 4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070 216591014433 HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase superfami, score 1.8e-10 216591014434 Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003 216591014435 active site 216591014436 hydrophilic channel; other site 216591014437 dimerization interface [polypeptide binding]; other site 216591014438 catalytic residues [active] 216591014439 active site lid [active] 216591014440 HMMPfam hit to PF03740, Pyridoxal phosphate biosynthesis protein Pdx, score 6.7e-138 216591014441 DNA repair protein RecO; Reviewed; Region: recO; PRK00085 216591014442 Recombination protein O N terminal; Region: RecO_N; pfam11967 216591014443 Recombination protein O C terminal; Region: RecO_C; pfam02565 216591014444 HMMPfam hit to PF02565, Recombination protein O, score 9.7e-21 216591014445 GTPase Era; Reviewed; Region: era; PRK00089 216591014446 E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163 216591014447 G1 box; other site 216591014448 GTP/Mg2+ binding site [chemical binding]; other site 216591014449 Switch I region; other site 216591014450 G2 box; other site 216591014451 Switch II region; other site 216591014452 G3 box; other site 216591014453 G4 box; other site 216591014454 G5 box; other site 216591014455 KH domain; Region: KH_2; pfam07650 216591014456 HMMPfam hit to PF07650, KH domain, score 1e-25 216591014457 HMMPfam hit to PF01926, GTPase of unknown function, score 1.6e-38 216591014458 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014459 ribonuclease III; Reviewed; Region: PRK12372 216591014460 RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593 216591014461 dimerization interface [polypeptide binding]; other site 216591014462 active site 216591014463 metal binding site [ion binding]; metal-binding site 216591014464 Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048 216591014465 HMMPfam hit to PF00035, Double-stranded RNA binding motif, score 1.3e-14 216591014466 HMMPfam hit to PF00636, RNase3 domain, score 5.8e-44 216591014467 PS00517 Ribonuclease III family signature. 216591014468 signal peptidase I; Provisional; Region: PRK10861 216591014469 The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530 216591014470 Catalytic site [active] 216591014471 The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530 216591014472 PS00761 Signal peptidases I signature 3. 216591014473 HMMPfam hit to PF00717, Peptidase S24-like, score 1.7e-26 216591014474 PS00760 Signal peptidases I lysine active site. 216591014475 PS00501 Signal peptidases I serine active site. 216591014476 2 probable transmembrane helices predicted for BCAL2866 by TMHMM2.0 at aa 4-26 and 72-94 216591014477 GTP-binding protein LepA; Provisional; Region: PRK05433 216591014478 LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890 216591014479 G1 box; other site 216591014480 putative GEF interaction site [polypeptide binding]; other site 216591014481 GTP/Mg2+ binding site [chemical binding]; other site 216591014482 Switch I region; other site 216591014483 G2 box; other site 216591014484 G3 box; other site 216591014485 Switch II region; other site 216591014486 G4 box; other site 216591014487 G5 box; other site 216591014488 lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699 216591014489 lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709 216591014490 GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421 216591014491 HMMPfam hit to PF06421, GTP-binding protein LepA C-terminus, score 2.2e-79 216591014492 HMMPfam hit to PF00679, Elongation factor G C-terminus, score 1.7e-35 216591014493 HMMPfam hit to PF03144, Elongation factor Tu domain, score 3.7e-10 216591014494 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 4.7e-70 216591014495 PS00301 GTP-binding elongation factors signature. 216591014496 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014497 Glutaredoxin-like domain (DUF836); Region: DUF836; pfam05768 216591014498 HMMPfam hit to PF05768, Glutaredoxin-like domain (DUF836), score 7e-25 216591014499 periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037 216591014500 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 216591014501 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 216591014502 protein binding site [polypeptide binding]; other site 216591014503 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 216591014504 protein binding site [polypeptide binding]; other site 216591014505 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 0.00082 216591014506 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 6.7e-08 216591014507 HMMPfam hit to PF00089, Trypsin, score 2.3e-16 216591014508 anti-sigma E factor; Provisional; Region: rseB; PRK09455 216591014509 Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026 216591014510 HMMPfam hit to PF03888, MucB/RseB family, score 3.8e-28 216591014511 Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872 216591014512 1 probable transmembrane helix predicted for BCAL2871 by TMHMM2.0 at aa 111-130 216591014513 RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939 216591014514 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591014515 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591014516 DNA binding residues [nucleotide binding] 216591014517 HMMPfam hit to PF04545, Sigma-70, region, score 2.4e-18 216591014518 HMMPfam hit to PF08281, Sigma-70, region, score 3.7e-20 216591014519 Predicted helix-turn-helix motif with score 1461.000, SD 4.16 at aa 156-177, sequence LSYEEIAEMMGCPIGTVRSRIF 216591014520 HMMPfam hit to PF04542, Sigma-70 region, score 2.9e-24 216591014521 PS01063 Sigma-70 factors ECF subfamily signature. 216591014522 2 probable transmembrane helices predicted for BCAL2873 by TMHMM2.0 at aa 21-43 and 47-69 216591014523 3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314 216591014524 Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834 216591014525 dimer interface [polypeptide binding]; other site 216591014526 active site 216591014527 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 1.8e-60 216591014528 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 6.9e-82 216591014529 PS00606 Beta-ketoacyl synthases active site. 216591014530 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014531 acyl carrier protein; Provisional; Region: acpP; PRK00982 216591014532 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.9e-22 216591014533 PS00012 Phosphopantetheine attachment site. 216591014534 beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333 216591014535 3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830 216591014536 NAD(P) binding site [chemical binding]; other site 216591014537 homotetramer interface [polypeptide binding]; other site 216591014538 homodimer interface [polypeptide binding]; other site 216591014539 active site 216591014540 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0031 216591014541 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.1e-36 216591014542 PS00061 Short-chain dehydrogenases/reductases family signature. 216591014543 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331 216591014544 malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128 216591014545 HMMPfam hit to PF00698, Acyl transferase domain, score 5.2e-11 216591014546 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014547 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352 216591014548 Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830 216591014549 dimer interface [polypeptide binding]; other site 216591014550 active site 216591014551 CoA binding pocket [chemical binding]; other site 216591014552 HMMPfam hit to PF08541, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 3.1e-55 216591014553 HMMPfam hit to PF08545, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 7.8e-49 216591014554 putative phosphate acyltransferase; Provisional; Region: PRK05331 216591014555 HMMPfam hit to PF02504, Fatty acid synthesis protein, score 2.5e-138 216591014556 PS00196 Type-1 copper (blue) proteins signature. 216591014557 50S ribosomal protein L32; Validated; Region: rpmF; PRK01110 216591014558 HMMPfam hit to PF01783, Ribosomal L32p protein family, score 5e-19 216591014559 Uncharacterized ACR, COG1399; Region: DUF177; pfam02620 216591014560 HMMPfam hit to PF02620, Uncharacterized ACR, COG1399, score 4.6e-19 216591014561 Maf-like protein; Region: Maf; pfam02545 216591014562 Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555 216591014563 active site 216591014564 dimer interface [polypeptide binding]; other site 216591014565 HMMPfam hit to PF02545, Maf-like protein, score 1.3e-45 216591014566 Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649 216591014567 putative SAM binding site [chemical binding]; other site 216591014568 homodimer interface [polypeptide binding]; other site 216591014569 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 2.3e-05 216591014570 Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023 216591014571 signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706 216591014572 tandem repeat interface [polypeptide binding]; other site 216591014573 oligomer interface [polypeptide binding]; other site 216591014574 active site residues [active] 216591014575 HMMPfam hit to PF01343, Peptidase family S49, score 6.7e-39 216591014576 1 probable transmembrane helix predicted for BCAL2884 by TMHMM2.0 at aa 45-67 216591014577 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467 216591014578 iron-sulfur cluster [ion binding]; other site 216591014579 [2Fe-2S] cluster binding site [ion binding]; other site 216591014580 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 1.5e-10 216591014581 Predicted phosphatases [General function prediction only]; Region: Gph; COG0546 216591014582 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591014583 motif II; other site 216591014584 HAD-hyrolase-like; Region: Hydrolase_like; pfam13242 216591014585 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1e-30 216591014586 23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025 216591014587 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940 216591014588 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 216591014589 active site 216591014590 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 1.9e-40 216591014591 PS01129 Rlu family of pseudouridine synthase signature. 216591014592 HMMPfam hit to PF01479, S4 domain, score 1.6e-07 216591014593 Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530 216591014594 S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453 216591014595 homodimer interface [polypeptide binding]; other site 216591014596 oligonucleotide binding site [chemical binding]; other site 216591014597 HMMPfam hit to PF00575, S1 RNA binding domain, score 2.3e-13 216591014598 molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164 216591014599 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591014600 FeS/SAM binding site; other site 216591014601 Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463 216591014602 HMMPfam hit to PF04055, Radical SAM superfamily, score 3.1e-38 216591014603 PS01305 moaA / nifB / pqqE family signature. 216591014604 HMMPfam hit to PF06463, Molybdenum Cofactor Synthesis C, score 2.4e-43 216591014605 molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317 216591014606 MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503 216591014607 GTP binding site; other site 216591014608 molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680 216591014609 MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887 216591014610 dimer interface [polypeptide binding]; other site 216591014611 putative functional site; other site 216591014612 putative MPT binding site; other site 216591014613 HMMPfam hit to PF03453, MoeA N-terminal region (domain I and II, score 9.6e-60 216591014614 HMMPfam hit to PF00994, Probable molybdopterin binding domain, score 3.8e-42 216591014615 HMMPfam hit to PF03454, MoeA C-terminal region (domain IV), score 2e-16 216591014616 2 probable transmembrane helices predicted for BCAL2892 by TMHMM2.0 at aa 16-38 and 48-70 216591014617 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014618 putative acetyltransferase; Provisional; Region: PRK03624 216591014619 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591014620 Coenzyme A binding pocket [chemical binding]; other site 216591014621 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.7e-23 216591014622 RmuC family; Region: RmuC; pfam02646 216591014623 HMMPfam hit to PF02646, RmuC family, score 7.9e-125 216591014624 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 216591014625 D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301 216591014626 dimerization interface [polypeptide binding]; other site 216591014627 ligand binding site [chemical binding]; other site 216591014628 NADP binding site [chemical binding]; other site 216591014629 catalytic site [active] 216591014630 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 1.7e-31 216591014631 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 2.1e-88 216591014632 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 216591014633 Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055 216591014634 Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221 216591014635 12 probable transmembrane helices predicted for BCAL2896 by TMHMM2.0 at aa 4-26, 33-55, 70-92, 99-116, 131-153, 166-188, 203-225, 258-280, 329-351, 372-394, 409-431 and 451-473 216591014636 Uncharacterized conserved protein [Function unknown]; Region: COG1556 216591014637 HMMPfam hit to PF02589, Uncharacterized ACR, YkgG family COG1556, score 1.5e-08 216591014638 nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514 216591014639 Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401 216591014640 active site 216591014641 HMMPfam hit to PF04095, Nicotinate phosphoribosyltransferase (NAPRTa, score 1.1e-106 216591014642 Ferredoxin [Energy production and conversion]; Region: COG1146 216591014643 4Fe-4S binding domain; Region: Fer4; cl02805 216591014644 Domain of unknown function (DUF3470); Region: DUF3470; pfam11953 216591014645 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0067 216591014646 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 1.1e-06 216591014647 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591014648 Uncharacterized protein conserved in bacteria [Function unknown]; Region: CreA; COG3045 216591014649 CreA protein; Region: CreA; pfam05981 216591014650 HMMPfam hit to PF05981, CreA protein, score 2e-78 216591014651 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 216591014652 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591014653 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591014654 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591014655 HMMPfam hit to PF02311, AraC-like ligand binding domain, score 1.8e-26 216591014656 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 1.9e-08 216591014657 Predicted helix-turn-helix motif with score 1320.000, SD 3.68 at aa 218-239, sequence VTLDEVAQAAGLSPFHAARLFT 216591014658 PS00041 Bacterial regulatory proteins, araC family signature. 216591014659 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 2.5e-05 216591014660 Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296 216591014661 HMMPfam hit to PF03591, AzlC protein, score 5.3e-53 216591014662 5 probable transmembrane helices predicted for BCAL2902 by TMHMM2.0 at aa 31-53, 65-87, 148-170, 177-199 and 214-236 216591014663 Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735 216591014664 HMMPfam hit to PF05437, Branched-chain amino acid transport protein, score 1.7e-20 216591014665 3 probable transmembrane helices predicted for BCAL2903 by TMHMM2.0 at aa 4-26, 33-55 and 88-110 216591014666 Protein of unknown function (DUF4088); Region: DUF4088; pfam13317 216591014667 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014668 S4 domain; Region: S4_2; pfam13275 216591014669 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131 216591014670 putative efflux protein, MATE family; Region: matE; TIGR00797 216591014671 cation binding site [ion binding]; other site 216591014672 HMMPfam hit to PF01554, MatE, score 2.4e-20 216591014673 11 probable transmembrane helices predicted for BCAL2907 by TMHMM2.0 at aa 56-78, 99-121, 141-163, 172-194, 204-226, 247-269, 279-301, 322-344, 359-381, 400-422 and 432-451 216591014674 HMMPfam hit to PF01554, MatE, score 2.8e-39 216591014675 PS00012 Phosphopantetheine attachment site. 216591014676 fumarate hydratase; Reviewed; Region: fumC; PRK00485 216591014677 Class II fumarases; Region: Fumarase_classII; cd01362 216591014678 active site 216591014679 tetramer interface [polypeptide binding]; other site 216591014680 HMMPfam hit to PF00206, Lyase, score 5e-178 216591014681 PS00163 Fumarate lyases signature. 216591014682 Brown fat-inducible thioesterase (BFIT). Brain acyl-CoA hydrolase (BACH). These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442 216591014683 HMMPfam hit to PF03061, Thioesterase superfamily, score 4.1e-21 216591014684 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591014685 dimerization interface [polypeptide binding]; other site 216591014686 putative DNA binding site [nucleotide binding]; other site 216591014687 putative Zn2+ binding site [ion binding]; other site 216591014688 HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family, score 0.00033 216591014689 Predicted helix-turn-helix motif with score 1041.000, SD 2.73 at aa 37-58, sequence RPAGELTMIAGLSPSAASAHLA 216591014690 FecR protein; Region: FecR; pfam04773 216591014691 1 probable transmembrane helix predicted for BCAL2911 by TMHMM2.0 at aa 13-32 216591014692 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014693 thymidylate synthase; Provisional; Region: thyA; PRK13821 216591014694 Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351 216591014695 dimerization interface [polypeptide binding]; other site 216591014696 active site 216591014697 HMMPfam hit to PF00303, Thymidylate synthase, score 3.9e-74 216591014698 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591014699 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 216591014700 Walker A motif; other site 216591014701 ATP binding site [chemical binding]; other site 216591014702 Walker B motif; other site 216591014703 arginine finger; other site 216591014704 Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420 216591014705 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 3.5e-11 216591014706 Predicted helix-turn-helix motif with score 2038.000, SD 6.13 at aa 418-439, sequence GRFADAARELGVSRVTLYRLMC 216591014707 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591014708 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3.2e-134 216591014709 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591014710 Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262 216591014711 Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209 216591014712 folate binding site [chemical binding]; other site 216591014713 NADP+ binding site [chemical binding]; other site 216591014714 HMMPfam hit to PF00186, Dihydrofolate reductase, score 1.3e-61 216591014715 peptidase PmbA; Provisional; Region: PRK11040 216591014716 HMMPfam hit to PF01523, Putative modulator of DNA gyrase, score 5.5e-53 216591014717 hypothetical protein; Provisional; Region: PRK05255 216591014718 HMMPfam hit to PF04751, Protein of unknown function (DUF615), score 3.1e-48 216591014719 MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886 216591014720 MPT binding site; other site 216591014721 trimer interface [polypeptide binding]; other site 216591014722 HMMPfam hit to PF00994, Probable molybdopterin binding domain, score 4e-27 216591014723 PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 216591014724 DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135 216591014725 catalytic site [active] 216591014726 putative active site [active] 216591014727 putative substrate binding site [chemical binding]; other site 216591014728 dimer interface [polypeptide binding]; other site 216591014729 HMMPfam hit to PF00929, Exonuclease, score 4e-34 216591014730 Peptidase family M48; Region: Peptidase_M48; pfam01435 216591014731 7 probable transmembrane helices predicted for BCAL2920 by TMHMM2.0 at aa 4-26, 67-89, 104-126, 147-169, 179-201, 294-316 and 331-353 216591014732 HMMPfam hit to PF01435, Peptidase family M48, score 2.2e-38 216591014733 GTPase RsgA; Reviewed; Region: PRK00098 216591014734 S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466 216591014735 RNA binding site [nucleotide binding]; other site 216591014736 homodimer interface [polypeptide binding]; other site 216591014737 Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854 216591014738 GTPase/Zn-binding domain interface [polypeptide binding]; other site 216591014739 GTP/Mg2+ binding site [chemical binding]; other site 216591014740 G4 box; other site 216591014741 G5 box; other site 216591014742 G1 box; other site 216591014743 Switch I region; other site 216591014744 G2 box; other site 216591014745 G3 box; other site 216591014746 Switch II region; other site 216591014747 HMMPfam hit to PF03193, Protein of unknown function, DUF258, score 6.6e-127 216591014748 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014749 Domain of unknown function (DUF2007); Region: DUF2007; pfam09413 216591014750 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014751 CobD/CbiB family protein; Provisional; Region: PRK07630 216591014752 HMMPfam hit to PF03186, CobD/Cbib protein, score 2.8e-06 216591014753 4 probable transmembrane helices predicted for BCAL2923 by TMHMM2.0 at aa 48-70, 72-94, 148-170 and 289-311 216591014754 Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426 216591014755 putative active site [active] 216591014756 putative CoA binding site [chemical binding]; other site 216591014757 nudix motif; other site 216591014758 metal binding site [ion binding]; metal-binding site 216591014759 HMMPfam hit to PF00293, NUDIX domain, score 2.1e-09 216591014760 50S ribosomal protein L19; Provisional; Region: rplS; PRK05338 216591014761 HMMPfam hit to PF01245, Ribosomal protein L19, score 7.3e-60 216591014762 PS01015 Ribosomal protein L19 signature. 216591014763 tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026 216591014764 HMMPfam hit to PF01746, tRNA (Guanine-1)-methyltransferase, score 4.1e-63 216591014765 16S rRNA processing protein RimM; Region: 16S_RimM; TIGR02273 216591014766 RimM N-terminal domain; Region: RimM; pfam01782 216591014767 PRC-barrel domain; Region: PRC; pfam05239 216591014768 HMMPfam hit to PF05239, PRC-barrel domain, score 8.3e-12 216591014769 HMMPfam hit to PF01782, RimM N-terminal domain, score 2.6e-12 216591014770 30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040 216591014771 HMMPfam hit to PF00886, Ribosomal protein S16, score 8e-28 216591014772 Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995 216591014773 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353 216591014774 4 probable transmembrane helices predicted for BCAL2930 by TMHMM2.0 at aa 15-34, 41-60, 70-92 and 113-135 216591014775 DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533 216591014776 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377 216591014777 FeS/SAM binding site; other site 216591014778 PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 216591014779 HMMPfam hit to PF04055, Radical SAM superfamily, score 1.2e-20 216591014780 Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412 216591014781 AsnC family; Region: AsnC_trans_reg; pfam01037 216591014782 HMMPfam hit to PF01037, AsnC family, score 8.3e-26 216591014783 PS00519 Bacterial regulatory proteins, asnC family signature. 216591014784 D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711 216591014785 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591014786 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 5.5e-109 216591014787 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014788 Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025 216591014789 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715 216591014790 Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766 216591014791 PS00696 Electron transfer flavoprotein alpha-subunit signature. 216591014792 HMMPfam hit to PF00766, Electron transfer flavoprotein FAD-binding, score 1.8e-54 216591014793 HMMPfam hit to PF01012, Electron transfer flavoprotein domain, score 2.8e-42 216591014794 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014795 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714 216591014796 Ligand binding site [chemical binding]; other site 216591014797 Electron transfer flavoprotein domain; Region: ETF; pfam01012 216591014798 HMMPfam hit to PF01012, Electron transfer flavoprotein domain, score 1.1e-67 216591014799 PS01065 Electron transfer flavoprotein beta-subunit signature. 216591014800 ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464 216591014801 NLPA lipoprotein; Region: Lipoprotein_9; pfam03180 216591014802 HMMPfam hit to PF03180, NLPA lipoprotein, score 6.1e-135 216591014803 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591014804 dimer interface [polypeptide binding]; other site 216591014805 conserved gate region; other site 216591014806 ABC-ATPase subunit interface; other site 216591014807 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.3e-21 216591014808 5 probable transmembrane helices predicted for BCAL2937 by TMHMM2.0 at aa 18-40, 60-82, 86-108, 146-168 and 188-210 216591014809 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591014810 DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153 216591014811 ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258 216591014812 Walker A/P-loop; other site 216591014813 ATP binding site [chemical binding]; other site 216591014814 Q-loop/lid; other site 216591014815 ABC transporter signature motif; other site 216591014816 Walker B; other site 216591014817 D-loop; other site 216591014818 H-loop/switch region; other site 216591014819 This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930 216591014820 HMMPfam hit to PF00005, ABC transporter, score 1.9e-66 216591014821 PS00211 ABC transporters family signature. 216591014822 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014823 Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267 216591014824 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591014825 Serine hydrolase; Region: Ser_hydrolase; cl17834 216591014826 HMMPfam hit to PF07819, PGAP1-like protein, score 0.002 216591014827 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 8.4e-07 216591014828 PS00120 Lipases, serine active site. 216591014829 Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123 216591014830 Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII_2; cd11599 216591014831 putative active site [active] 216591014832 Zn binding site [ion binding]; other site 216591014833 HMMPfam hit to PF00850, Histone deacetylase domain, score 1.1e-83 216591014834 Transglycosylase SLT domain; Region: SLT_2; pfam13406 216591014835 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591014836 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591014837 1 probable transmembrane helix predicted for BCAL2941 by TMHMM2.0 at aa 13-35 216591014838 cysteine synthase B; Region: cysM; TIGR01138 216591014839 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 216591014840 dimer interface [polypeptide binding]; other site 216591014841 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591014842 catalytic residue [active] 216591014843 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 2.2e-93 216591014844 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014845 PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 216591014846 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786 216591014847 HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 0.0052 216591014848 ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248 216591014849 ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197 216591014850 NADP binding site [chemical binding]; other site 216591014851 homopentamer interface [polypeptide binding]; other site 216591014852 substrate binding site [chemical binding]; other site 216591014853 active site 216591014854 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 1.6e-55 216591014855 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 1.4e-05 216591014856 HMMPfam hit to PF07993, Male sterility protein, score 0.0048 216591014857 RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172 216591014858 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 216591014859 putative ribose interaction site [chemical binding]; other site 216591014860 putative ADP binding site [chemical binding]; other site 216591014861 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 8.5e-38 216591014862 PS00583 pfkB family of carbohydrate kinases signature 1. 216591014863 Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004 216591014864 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210 216591014865 UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984 216591014866 UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984 216591014867 HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 3.6e-33 216591014868 HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 6.5e-51 216591014869 HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 6.1e-88 216591014870 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014871 tetratricopeptide repeat protein; Provisional; Region: PRK11788 216591014872 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591014873 binding surface 216591014874 TPR motif; other site 216591014875 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.31 216591014876 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.2 216591014877 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.35 216591014878 1 probable transmembrane helix predicted for BCAL2947 by TMHMM2.0 at aa 5-22 216591014879 2 probable transmembrane helices predicted for BCAL2948 by TMHMM2.0 at aa 21-40 and 55-77 216591014880 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 216591014881 IHF dimer interface [polypeptide binding]; other site 216591014882 IHF - DNA interface [nucleotide binding]; other site 216591014883 HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 3.1e-42 216591014884 30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299 216591014885 S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687 216591014886 RNA binding site [nucleotide binding]; other site 216591014887 S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465 216591014888 RNA binding site [nucleotide binding]; other site 216591014889 S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688 216591014890 RNA binding site [nucleotide binding]; other site 216591014891 S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689 216591014892 RNA binding site [nucleotide binding]; other site 216591014893 S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690 216591014894 RNA binding site [nucleotide binding]; other site 216591014895 S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691 216591014896 RNA binding site [nucleotide binding]; other site 216591014897 HMMPfam hit to PF00575, S1 RNA binding domain, score 3.9e-19 216591014898 HMMPfam hit to PF00575, S1 RNA binding domain, score 2.2e-21 216591014899 HMMPfam hit to PF00575, S1 RNA binding domain, score 5.7e-27 216591014900 HMMPfam hit to PF00575, S1 RNA binding domain, score 1.4e-31 216591014901 HMMPfam hit to PF00575, S1 RNA binding domain, score 4.7e-16 216591014902 HMMPfam hit to PF00575, S1 RNA binding domain, score 3.8e-07 216591014903 cytidylate kinase; Provisional; Region: cmk; PRK00023 216591014904 Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020 216591014905 CMP-binding site; other site 216591014906 HMMPfam hit to PF02224, Cytidylate kinase, score 2.7e-62 216591014907 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427 216591014908 EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556 216591014909 hinge; other site 216591014910 active site 216591014911 HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 8.7e-164 216591014912 PS00885 EPSP synthase signature 2. 216591014913 PS00104 EPSP synthase signature 1. 216591014914 Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287 216591014915 prephenate dehydrogenase; Validated; Region: PRK08507 216591014916 HMMPfam hit to PF02153, Prephenate dehydrogenase, score 1.5e-83 216591014917 Chorismate mutase type II; Region: CM_2; smart00830 216591014918 Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077 216591014919 Prephenate dehydratase; Region: PDT; pfam00800 216591014920 C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905 216591014921 putative L-Phe binding site [chemical binding]; other site 216591014922 HMMPfam hit to PF01842, ACT domain, score 1.8e-11 216591014923 HMMPfam hit to PF00800, Prephenate dehydratase, score 2.1e-72 216591014924 HMMPfam hit to PF01817, Chorismate mutase type II, score 1e-29 216591014925 Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520 216591014926 Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as...; Region: PSAT_like; cd00611 216591014927 homodimer interface [polypeptide binding]; other site 216591014928 substrate-cofactor binding pocket; other site 216591014929 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591014930 catalytic residue [active] 216591014931 HMMPfam hit to PF00266, Aminotransferase class-V, score 1.5e-37 216591014932 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 216591014933 Uncharacterized protein conserved in bacteria (DUF2059); Region: DUF2059; pfam09832 216591014934 DNA gyrase subunit A; Validated; Region: PRK05560 216591014935 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187 216591014936 CAP-like domain; other site 216591014937 active site 216591014938 primary dimer interface [polypeptide binding]; other site 216591014939 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 216591014940 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 216591014941 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 216591014942 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 216591014943 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 216591014944 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 216591014945 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 6.4e-15 216591014946 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 3.3e-15 216591014947 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 8.8e-13 216591014948 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 7e-10 216591014949 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 1.1e-13 216591014950 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 3.9e-14 216591014951 HMMPfam hit to PF00521, DNA gyrase/topoisomerase IV, subunit A, score 0 216591014952 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591014953 ligand binding site [chemical binding]; other site 216591014954 HMMPfam hit to PF00691, OmpA family, score 6.4e-34 216591014955 bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134 216591014956 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591014957 S-adenosylmethionine binding site [chemical binding]; other site 216591014958 HMMPfam hit to PF02353, Cyclopropane-fatty-acyl-phospholipid, score 0.0033 216591014959 HMMPfam hit to PF08241, Methyltransferase domain, score 6.8e-24 216591014960 HMMPfam hit to PF08242, Methyltransferase domain, score 3.9e-14 216591014961 phosphoglycolate phosphatase; Provisional; Region: PRK13222 216591014962 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591014963 motif II; other site 216591014964 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.3e-32 216591014965 BcenGI9 216591014966 integrase; Provisional; Region: PRK09692 216591014967 Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801 216591014968 active site 216591014969 Int/Topo IB signature motif; other site 216591014970 HMMPfam hit to PF00589, Phage integrase family, score 6.6e-12 216591014971 CRISPR/Cas system-associated protein Cas3/Cas2; Region: Cas3_Cas2_I-F; cd09673 216591014972 UV radiation resistance protein and autophagy-related subunit 14; Region: Atg14; pfam10186 216591014973 Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523 216591014974 HMMPfam hit to PF05930, Prophage CP4-57 regulatory protein (AlpA), score 0.0031 216591014975 KilA-N domain; Region: KilA-N; pfam04383 216591014976 HMMPfam hit to PF04383, KilA-N domain, score 1.8e-13 216591014977 Helix-turn-helix domain; Region: HTH_39; pfam14090 216591014978 Primase C terminal 2 (PriCT-2); Region: PriCT_2; pfam08707 216591014979 Domain of unknown function (DUF927); Region: DUF927; pfam06048 216591014980 PS00216 Sugar transport proteins signature 1. 216591014981 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591014982 PS00017 ATP/GTP-binding site motif A (P-loop). 216591014983 phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644 216591014984 Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930 216591014985 generic binding surface I; other site 216591014986 generic binding surface II; other site 216591014987 Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; cl10713 216591014988 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591014989 1 probable transmembrane helix predicted for BCAL2973 by TMHMM2.0 at aa 4-26 216591014990 1 probable transmembrane helix predicted for BCAL2974 by TMHMM2.0 at aa 40-62 216591014991 N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; cl17549 216591014992 aminoethylphosphonate catabolism associated LysR family transcriptional regulator; Region: phn_lysR; TIGR03339 216591014993 PBP superfamily domain; Region: PBP_like; pfam12727 216591014994 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 2.6e-10 216591014995 Predicted helix-turn-helix motif with score 991.000, SD 2.56 at aa 36-57, sequence GSIAQAAQAKGLSYRHAWGMLR 216591014996 formate dehydrogenase subunit gamma; Validated; Region: PRK05988 216591014997 TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily, NAD-dependent formate dehydrogenase (FDH) gamma subunit; composed of proteins similar to the gamma subunit of NAD-linked FDH of Ralstonia eutropha, a...; Region: TRX_Fd_NuoE_FDH_gamma; cd03081 216591014998 putative dimer interface [polypeptide binding]; other site 216591014999 [2Fe-2S] cluster binding site [ion binding]; other site 216591015000 TRX-like [2Fe-2S] Ferredoxin (Fd) family, NAD-dependent formate dehydrogenase (FDH) beta subunit; composed of proteins similar to the beta subunit of NAD-linked FDH of Ralstonia eutropha, a soluble enzyme that catalyzes the irreversible oxidation of...; Region: TRX_Fd_FDH_beta; cd03063 216591015001 putative dimer interface [polypeptide binding]; other site 216591015002 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894 216591015003 SLBB domain; Region: SLBB; pfam10531 216591015004 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928 216591015005 HMMPfam hit to PF01512, Respiratory-chain NADH dehydrogenase, score 1.2e-102 216591015006 PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 216591015007 Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383 216591015008 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591015009 catalytic loop [active] 216591015010 iron binding site [ion binding]; other site 216591015011 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588 216591015012 Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753 216591015013 [4Fe-4S] binding site [ion binding]; other site 216591015014 molybdopterin cofactor binding site; other site 216591015015 This CD includes formate dehydrogenases (Fdh) H and N; nitrate reductases, Nap and Nas; and other related proteins. Formate dehydrogenase H is a component of the anaerobic formate hydrogen lyase complex and catalyzes the reversible oxidation of formate...; Region: MopB_CT_Fdh-Nap-like; cd00508 216591015016 molybdopterin cofactor binding site; other site 216591015017 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding do, score 4.9e-09 216591015018 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0053 216591015019 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591015020 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 2.7e-05 216591015021 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591015022 HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 do, score 4.2e-20 216591015023 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 216591015024 HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 1.5e-103 216591015025 HMMPfam hit to PF01568, Molydopterin dinucleotide binding dom, score 6.8e-42 216591015026 PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 216591015027 NADH-dependant formate dehydrogenase delta subunit FdsD; Region: FdsD; pfam11390 216591015028 hypothetical protein; Provisional; Region: PRK06184 216591015029 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591015030 HMMPfam hit to PF01494, FAD binding domain, score 1.7e-86 216591015031 Tetratricopeptide repeat; Region: TPR_16; pfam13432 216591015032 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591015033 binding surface 216591015034 TPR motif; other site 216591015035 TPR repeat; Region: TPR_11; pfam13414 216591015036 TPR repeat; Region: TPR_11; pfam13414 216591015037 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591015038 binding surface 216591015039 TPR motif; other site 216591015040 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591015041 TPR repeat; Region: TPR_11; pfam13414 216591015042 TPR motif; other site 216591015043 binding surface 216591015044 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 216591015045 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0012 216591015046 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.4e-06 216591015047 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 0.02 216591015048 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.7e-10 216591015049 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 0.002 216591015050 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 8.6e-10 216591015051 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 0.0033 216591015052 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.00056 216591015053 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 0.029 216591015054 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 8e-06 216591015055 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 0.032 216591015056 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 9.5e-05 216591015057 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 9e-07 216591015058 citrate-proton symporter; Provisional; Region: PRK15075 216591015059 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591015060 putative substrate translocation pore; other site 216591015061 HMMPfam hit to PF00083, Sugar (and other) transporter, score 5.4e-42 216591015062 12 probable transmembrane helices predicted for BCAL2982 by TMHMM2.0 at aa 20-42, 57-79, 88-110, 120-142, 163-182, 187-207, 239-261, 276-298, 305-327, 337-356, 369-391 and 401-419 216591015063 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.3e-22 216591015064 PS00216 Sugar transport proteins signature 1. 216591015065 PS00217 Sugar transport proteins signature 2. 216591015066 1 probable transmembrane helix predicted for BCAL2982A by TMHMM2.0 at aa 105-124 216591015067 Protein of unknown function (DUF2968); Region: DUF2968; pfam11180 216591015068 Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071 216591015069 Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745 216591015070 catalytic triad [active] 216591015071 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 5.5e-05 216591015072 HMMPfam hit to PF07722, Peptidase C26, score 9.4e-49 216591015073 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015074 Transcriptional regulators [Transcription]; Region: GntR; COG1802 216591015075 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591015076 DNA-binding site [nucleotide binding]; DNA binding site 216591015077 FCD domain; Region: FCD; pfam07729 216591015078 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.6e-13 216591015079 HMMPfam hit to PF07729, FCD domain, score 3.6e-30 216591015080 amidase; Provisional; Region: PRK07056 216591015081 Amidase; Region: Amidase; cl11426 216591015082 HMMPfam hit to PF01425, Amidase, score 8.7e-103 216591015083 PS00571 Amidases signature. 216591015084 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015085 disulfide bond formation protein B; Provisional; Region: PRK02110 216591015086 HMMPfam hit to PF02600, Disulfide bond formation protein DsbB, score 9.8e-13 216591015087 4 probable transmembrane helices predicted for BCAL2987 by TMHMM2.0 at aa 13-35, 45-64, 69-91 and 137-159 216591015088 XdhC and CoxI family; Region: XdhC_CoxI; pfam02625 216591015089 xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964 216591015090 XdhC Rossmann domain; Region: XdhC_C; pfam13478 216591015091 HMMPfam hit to PF02625, XdhC and CoxI family, score 3e-17 216591015092 Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816 216591015093 Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320 216591015094 active site 216591015095 purine riboside binding site [chemical binding]; other site 216591015096 HMMPfam hit to PF00962, Adenosine/AMP deaminase, score 7.5e-73 216591015097 guanine deaminase; Provisional; Region: PRK09228 216591015098 Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303 216591015099 active site 216591015100 HMMPfam hit to PF01979, Amidohydrolase family, score 3.5e-51 216591015101 HMMPfam hit to PF07969, Amidohydrolase family, score 0.00056 216591015102 Predicted membrane protein [Function unknown]; Region: COG2119 216591015103 Uncharacterized protein family UPF0016; Region: UPF0016; pfam01169 216591015104 Uncharacterized protein family UPF0016; Region: UPF0016; pfam01169 216591015105 5 probable transmembrane helices predicted for BCAL2991 by TMHMM2.0 at aa 35-57, 67-86, 98-115, 135-157 and 169-188 216591015106 HMMPfam hit to PF01169, Uncharacterized protein family UPF0016, score 2.1e-12 216591015107 Domain of unknown function (DUF4136); Region: DUF4136; pfam13590 216591015108 1 probable transmembrane helix predicted for BCAL2992 by TMHMM2.0 at aa 7-29 216591015109 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015110 aminopeptidase N; Provisional; Region: pepN; PRK14015 216591015111 Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600 216591015112 active site 216591015113 Zn binding site [ion binding]; other site 216591015114 HMMPfam hit to PF01433, Peptidase family M1, score 8.1e-59 216591015115 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591015116 fructose-1,6-bisphosphatase family protein; Region: PLN02628 216591015117 Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354 216591015118 AMP binding site [chemical binding]; other site 216591015119 metal binding site [ion binding]; metal-binding site 216591015120 active site 216591015121 HMMPfam hit to PF00316, Fructose-1-6-bisphosphatase, score 1.9e-168 216591015122 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591015123 DNA binding residues [nucleotide binding] 216591015124 dimerization interface [polypeptide binding]; other site 216591015125 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 3.2e-11 216591015126 PS00622 Bacterial regulatory proteins, luxR family signature. 216591015127 FAD-dependent oxidoreductase; Provisional; Region: PRK08132 216591015128 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591015129 HMMPfam hit to PF01494, FAD binding domain, score 1.1e-45 216591015130 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00016 216591015131 3 probable transmembrane helices predicted for BCAL2998 by TMHMM2.0 at aa 4-23, 28-50 and 55-77 216591015132 HMMPfam hit to PF04226, Transglycosylase associated protein, score 1.3e-13 216591015133 Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388 216591015134 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591015135 BNR repeat-like domain; Region: BNR_2; pfam13088 216591015136 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 2.7 216591015137 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 8.4 216591015138 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 1.4 216591015139 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 52 216591015140 Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629 216591015141 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591015142 N-terminal plug; other site 216591015143 ligand-binding site [chemical binding]; other site 216591015144 HMMPfam hit to PF00593, TonB dependent receptor, score 7.6e-31 216591015145 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.9e-17 216591015146 Protein of unknown function (DUF2946); Region: DUF2946; pfam11162 216591015147 1 probable transmembrane helix predicted for BCAL3002 by TMHMM2.0 at aa 7-29 216591015148 chorismate mutase; Provisional; Region: PRK09269 216591015149 Chorismate mutase type II; Region: CM_2; cl00693 216591015150 HMMPfam hit to PF01817, Chorismate mutase type II, score 2.7e-09 216591015151 DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127 216591015152 active site 216591015153 catalytic site [active] 216591015154 substrate binding site [chemical binding]; other site 216591015155 Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434 216591015156 GIY-YIG motif/motif A; other site 216591015157 active site 216591015158 catalytic site [active] 216591015159 putative DNA binding site [nucleotide binding]; other site 216591015160 metal binding site [ion binding]; metal-binding site 216591015161 HMMPfam hit to PF01541, GIY-YIG catalytic domain, score 2.4e-06 216591015162 HMMPfam hit to PF00929, Exonuclease, score 1.3e-33 216591015163 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 216591015164 DNA-binding site [nucleotide binding]; DNA binding site 216591015165 RNA-binding motif; other site 216591015166 HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 6.6e-38 216591015167 PS00352 'Cold-shock' DNA-binding domain signature. 216591015168 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591015169 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591015170 trimer interface [polypeptide binding]; other site 216591015171 eyelet of channel; other site 216591015172 HMMPfam hit to PF00267, Gram-negative porin, score 1e-06 216591015173 PS00572 Glycosyl hydrolases family 1 active site. 216591015174 transcription elongation factor GreB; Reviewed; Region: greB; PRK01885 216591015175 Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449 216591015176 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 216591015177 HMMPfam hit to PF01272, Prokaryotic transcription elongation fact, score 3e-21 216591015178 PS00830 Prokaryotic transcription elongation factors signature 2. 216591015179 HMMPfam hit to PF03449, Prokaryotic transcription elongation fact, score 2.7e-35 216591015180 PS00829 Prokaryotic transcription elongation factors signature 1. 216591015181 Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317 216591015182 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 216591015183 Zn2+ binding site [ion binding]; other site 216591015184 Mg2+ binding site [ion binding]; other site 216591015185 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 216591015186 synthetase active site [active] 216591015187 NTP binding site [chemical binding]; other site 216591015188 metal binding site [ion binding]; metal-binding site 216591015189 TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668 216591015190 ACT domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876 216591015191 HMMPfam hit to PF01842, ACT domain, score 0.0046 216591015192 HMMPfam hit to PF02824, TGS domain, score 4.6e-24 216591015193 HMMPfam hit to PF04607, Region found in RelA / SpoT proteins, score 1.8e-44 216591015194 HMMPfam hit to PF01966, HD domain, score 1.4e-13 216591015195 DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392 216591015196 HMMPfam hit to PF01192, RNA polymerase Rpb6, score 1.4e-14 216591015197 Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194 216591015198 Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071 216591015199 catalytic site [active] 216591015200 G-X2-G-X-G-K; other site 216591015201 HMMPfam hit to PF00625, Guanylate kinase, score 4.2e-40 216591015202 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015203 hypothetical protein; Provisional; Region: PRK11820 216591015204 YicC-like family, N-terminal region; Region: YicC_N; pfam03755 216591015205 Domain of unknown function (DUF1732); Region: DUF1732; pfam08340 216591015206 HMMPfam hit to PF08340, Domain of unknown function (DUF1732), score 3.2e-51 216591015207 HMMPfam hit to PF03755, YicC-like family, N-terminal region, score 1.2e-37 216591015208 ribonuclease PH; Reviewed; Region: rph; PRK00173 216591015209 Ribonuclease PH; Region: RNase_PH_bact; cd11362 216591015210 hexamer interface [polypeptide binding]; other site 216591015211 active site 216591015212 HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 1.6e-48 216591015213 PS01277 Ribonuclease PH signature. 216591015214 HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 5.9e-18 216591015215 NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515 216591015216 active site 216591015217 dimerization interface [polypeptide binding]; other site 216591015218 HMMPfam hit to PF01725, Ham1 family, score 6.6e-67 216591015219 coproporphyrinogen III oxidase; Provisional; Region: PRK08898 216591015220 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591015221 FeS/SAM binding site; other site 216591015222 HemN C-terminal domain; Region: HemN_C; pfam06969 216591015223 HMMPfam hit to PF04055, Radical SAM superfamily, score 7.7e-26 216591015224 HMMPfam hit to PF06969, HemN C-terminal region, score 2.7e-23 216591015225 Gram-negative bacterial tonB protein; Region: TonB; cl10048 216591015226 1 probable transmembrane helix predicted for BCAL3019 by TMHMM2.0 at aa 12-34 216591015227 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015228 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591015229 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591015230 putative substrate translocation pore; other site 216591015231 HMMPfam hit to PF00083, Sugar (and other) transporter, score 9.2e-22 216591015232 11 probable transmembrane helices predicted for BCAL3020 by TMHMM2.0 at aa 24-46, 66-88, 95-117, 166-188, 195-217, 250-272, 285-307, 317-336, 343-365, 375-397 and 404-426 216591015233 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.9e-21 216591015234 PS00216 Sugar transport proteins signature 1. 216591015235 2 probable transmembrane helices predicted for BCAL3021 by TMHMM2.0 at aa 28-50 and 57-79 216591015236 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859 216591015237 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 216591015238 putative active site [active] 216591015239 HMMPfam hit to PF01075, Glycosyltransferase family, score 6.1e-24 216591015240 Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038 216591015241 ClC chloride channel family. These protein sequences, closely related to the ClC Eric family, are putative halogen ion (Cl-, Br- and I-) transport proteins found in eubacteria. They belong to the ClC superfamily of chloride ion channels, which share a...; Region: EriC_like; cd01034 216591015242 putative ion selectivity filter; other site 216591015243 putative pore gating glutamate residue; other site 216591015244 putative H+/Cl- coupling transport residue; other site 216591015245 10 probable transmembrane helices predicted for BCAL3023 by TMHMM2.0 at aa 24-45, 60-77, 109-131, 165-187, 194-216, 236-258, 278-300, 329-351, 358-380 and 390-412 216591015246 HMMPfam hit to PF00654, Voltage gated chloride channel, score 2.2e-22 216591015247 PS00044 Bacterial regulatory proteins, lysR family signature. 216591015248 cell division topological specificity factor MinE; Provisional; Region: PRK13989 216591015249 HMMPfam hit to PF03776, Septum formation topological specificity fac, score 1.3e-36 216591015250 Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894 216591015251 Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036 216591015252 Switch I; other site 216591015253 Switch II; other site 216591015254 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 7.3e-26 216591015255 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015256 septum formation inhibitor; Reviewed; Region: PRK01973 216591015257 Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209 216591015258 Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775 216591015259 HMMPfam hit to PF03775, Septum formation inhibitor MinC, C-terminal, score 2.7e-65 216591015260 HMMPfam hit to PF05209, Septum formation inhibitor MinC, N-terminal, score 0.00022 216591015261 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591015262 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.4e-14 216591015263 Alkane hydroxylase is a bacterial, integral-membrane di-iron enzyme that shares a requirement for iron and oxygen for activity similar to that of the non-heme integral-membrane acyl coenzyme A (CoA) desaturases and acyl lipid desaturases. The alk genes...; Region: Alkane-hydroxylase; cd03512 216591015264 Fatty acid desaturase; Region: FA_desaturase; pfam00487 216591015265 Di-iron ligands [ion binding]; other site 216591015266 6 probable transmembrane helices predicted for BCAL3029 by TMHMM2.0 at aa 17-39, 43-65, 86-108, 112-134, 235-257 and 330-352 216591015267 HMMPfam hit to PF00487, Fatty acid desaturase, score 2e-09 216591015268 seryl-tRNA synthetase; Provisional; Region: PRK05431 216591015269 Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403 216591015270 Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770 216591015271 dimer interface [polypeptide binding]; other site 216591015272 active site 216591015273 motif 1; other site 216591015274 motif 2; other site 216591015275 motif 3; other site 216591015276 HMMPfam hit to PF00587, tRNA synthetase class II core domain (G,, score 5.9e-65 216591015277 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591015278 HMMPfam hit to PF02403, Seryl-tRNA synthetase N-terminal domain, score 6.6e-45 216591015279 Uncharacterized conserved protein (DUF2164); Region: DUF2164; pfam09932 216591015280 recombination factor protein RarA; Reviewed; Region: PRK13342 216591015281 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591015282 Walker A motif; other site 216591015283 ATP binding site [chemical binding]; other site 216591015284 Walker B motif; other site 216591015285 arginine finger; other site 216591015286 MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002 216591015287 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 7.1e-18 216591015288 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 0.00079 216591015289 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015290 lipoprotein chaperone; Reviewed; Region: lolA; PRK00031 216591015291 Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548 216591015292 HMMPfam hit to PF03548, Outer membrane lipoprotein carrier protein L, score 6.4e-43 216591015293 Domain of unknown function (DUF4117); Region: DUF4117; pfam13491 216591015294 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 216591015295 Ftsk gamma domain; Region: Ftsk_gamma; pfam09397 216591015296 HMMPfam hit to PF01580, FtsK/SpoIIIE family, score 1.5e-78 216591015297 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015298 3 probable transmembrane helices predicted for BCAL3034 by TMHMM2.0 at aa 21-43, 68-90 and 164-186 216591015299 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015300 thioredoxin reductase; Provisional; Region: PRK10262 216591015301 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591015302 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591015303 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 1.2e-45 216591015304 PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 216591015305 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 5.5e-22 216591015306 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840 216591015307 Smr domain; Region: Smr; pfam01713 216591015308 HMMPfam hit to PF01713, Smr domain, score 1.1e-28 216591015309 Predicted membrane protein [Function unknown]; Region: COG2860 216591015310 UPF0126 domain; Region: UPF0126; pfam03458 216591015311 UPF0126 domain; Region: UPF0126; pfam03458 216591015312 7 probable transmembrane helices predicted for BCAL3037 by TMHMM2.0 at aa 5-27, 34-56, 69-88, 95-117, 122-144, 157-174 and 178-197 216591015313 HMMPfam hit to PF03458, UPF0126 domain, score 3.1e-12 216591015314 HMMPfam hit to PF03458, UPF0126 domain, score 2.1e-26 216591015315 glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650 216591015316 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 216591015317 Walker A/P-loop; other site 216591015318 ATP binding site [chemical binding]; other site 216591015319 Q-loop/lid; other site 216591015320 ABC transporter signature motif; other site 216591015321 Walker B; other site 216591015322 D-loop; other site 216591015323 H-loop/switch region; other site 216591015324 TOBE domain; Region: TOBE_2; pfam08402 216591015325 HMMPfam hit to PF08402, TOBE domain, score 6.9e-08 216591015326 HMMPfam hit to PF03459, TOBE domain, score 0.00021 216591015327 HMMPfam hit to PF00005, ABC transporter, score 2.6e-62 216591015328 PS00211 ABC transporters family signature. 216591015329 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015330 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015331 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 216591015332 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591015333 dimer interface [polypeptide binding]; other site 216591015334 conserved gate region; other site 216591015335 putative PBP binding loops; other site 216591015336 ABC-ATPase subunit interface; other site 216591015337 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.2e-15 216591015338 7 probable transmembrane helices predicted for BCAL3039 by TMHMM2.0 at aa 7-29, 82-104, 111-133, 143-165, 186-208, 218-240 and 253-275 216591015339 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591015340 dimer interface [polypeptide binding]; other site 216591015341 conserved gate region; other site 216591015342 putative PBP binding loops; other site 216591015343 ABC-ATPase subunit interface; other site 216591015344 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.0034 216591015345 6 probable transmembrane helices predicted for BCAL3040 by TMHMM2.0 at aa 13-35, 70-92, 104-126, 155-177, 211-233 and 259-281 216591015346 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 216591015347 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 216591015348 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 6.2e-15 216591015349 glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722 216591015350 Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479 216591015351 Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781 216591015352 HMMPfam hit to PF00479, Glucose-6-phosphate dehydrogenase, NAD bindi, score 1.8e-76 216591015353 PS00069 Glucose-6-phosphate dehydrogenase active site. 216591015354 HMMPfam hit to PF02781, Glucose-6-phosphate dehydrogenase, C-termina, score 1.8e-141 216591015355 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363 216591015356 6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400 216591015357 putative active site [active] 216591015358 bifunctional glucokinase/RpiR family transcriptional regulator; Provisional; Region: PRK14101 216591015359 glucokinase; Provisional; Region: glk; PRK00292 216591015360 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 216591015361 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 216591015362 putative active site [active] 216591015363 HMMPfam hit to PF02685, Glucokinase, score 1.6e-171 216591015364 HMMPfam hit to PF01418, Helix-turn-helix domain, rpiR family, score 3.7e-21 216591015365 Predicted helix-turn-helix motif with score 1301.000, SD 3.62 at aa 375-396, sequence DPIVDIARKADVSQPTVIRFCR 216591015366 PS00356 Bacterial regulatory proteins, lacI family signature. 216591015367 HMMPfam hit to PF01380, SIS domain, score 1.1e-19 216591015368 putative transposase OrfB; Reviewed; Region: PHA02517 216591015369 HTH-like domain; Region: HTH_21; pfam13276 216591015370 Integrase core domain; Region: rve; pfam00665 216591015371 Integrase core domain; Region: rve_2; pfam13333 216591015372 HMMPfam hit to PF00665, Integrase core domain, score 5.1e-42 216591015373 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591015374 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591015375 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591015376 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591015377 Predicted helix-turn-helix motif with score 1703.000, SD 4.99 at aa 20-41, sequence EAIRAVARTHGLSHSTVSQWYA 216591015378 bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102 216591015379 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591015380 putative substrate translocation pore; other site 216591015381 12 probable transmembrane helices predicted for BCAL3047 by TMHMM2.0 at aa 13-32, 52-71, 78-100, 104-126, 138-160, 165-187, 216-238, 253-271, 278-300, 304-326, 346-368 and 372-394 216591015382 HMMPfam hit to PF00083, Sugar (and other) transporter, score 0.00017 216591015383 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5e-52 216591015384 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015385 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015386 glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062 216591015387 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591015388 inhibitor-cofactor binding pocket; inhibition site 216591015389 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591015390 catalytic residue [active] 216591015391 HMMPfam hit to PF00202, Aminotransferase class-III, score 1.9e-75 216591015392 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591015393 riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326 216591015394 Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284 216591015395 catalytic motif [active] 216591015396 Zn binding site [ion binding]; other site 216591015397 RibD C-terminal domain; Region: RibD_C; cl17279 216591015398 HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 2.9e-41 216591015399 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 216591015400 HMMPfam hit to PF01872, RibD C-terminal domain, score 1.4e-56 216591015401 riboflavin synthase subunit alpha; Provisional; Region: PRK09289 216591015402 Lumazine binding domain; Region: Lum_binding; pfam00677 216591015403 Lumazine binding domain; Region: Lum_binding; pfam00677 216591015404 HMMPfam hit to PF00677, Lumazine binding domain, score 9.6e-11 216591015405 HMMPfam hit to PF00677, Lumazine binding domain, score 5.1e-26 216591015406 PS00693 Riboflavin synthase alpha chain family signature. 216591015407 Domain of unknown function (DUF1993); Region: DUF1993; pfam09351 216591015408 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Provisional; Region: PRK14019 216591015409 3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926 216591015410 GTP cyclohydrolase II; Region: GTP_cyclohydro2; pfam00925 216591015411 dimerization interface [polypeptide binding]; other site 216591015412 active site 216591015413 HMMPfam hit to PF00926, 3,4-dihydroxy-2-butanone 4-phosphate, score 3.2e-112 216591015414 HMMPfam hit to PF00925, GTP cyclohydrolase II, score 2.7e-09 216591015415 lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209 216591015416 homopentamer interface [polypeptide binding]; other site 216591015417 active site 216591015418 HMMPfam hit to PF00885, 6,7-dimethyl-8-ribityllumazine synthase, score 2.8e-51 216591015419 transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202 216591015420 putative RNA binding site [nucleotide binding]; other site 216591015421 HMMPfam hit to PF01029, NusB family, score 2.1e-27 216591015422 aminotransferase; Validated; Region: PRK07337 216591015423 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591015424 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591015425 homodimer interface [polypeptide binding]; other site 216591015426 catalytic residue [active] 216591015427 HMMPfam hit to PF00155, Aminotransferase class I and II, score 4.6e-63 216591015428 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015429 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 216591015430 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015431 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 216591015432 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591015433 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591015434 catalytic residue [active] 216591015435 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 6.5e-14 216591015436 1 probable transmembrane helix predicted for BCAL3057 by TMHMM2.0 at aa 27-49 216591015437 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015438 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311 216591015439 HMMPfam hit to PF01977, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, score 2.9e-186 216591015440 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591015441 PS00024 Hemopexin domain signature. 216591015442 LysE type translocator; Region: LysE; cl00565 216591015443 6 probable transmembrane helices predicted for BCAL3059 by TMHMM2.0 at aa 13-35, 42-64, 74-93, 124-146, 156-175 and 196-218 216591015444 HMMPfam hit to PF01810, LysE type translocator, score 1e-29 216591015445 2 probable transmembrane helices predicted for BCAL3059A by TMHMM2.0 at aa 20-42 and 57-79 216591015446 NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807 216591015447 Domain of unknown function (DUF2520); Region: DUF2520; pfam10728 216591015448 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 0.00066 216591015449 HMMPfam hit to PF03807, NADP oxidoreductase coenzyme F420-depen, score 0.00026 216591015450 YGGT family; Region: YGGT; pfam02325 216591015451 YGGT family; Region: YGGT; pfam02325 216591015452 4 probable transmembrane helices predicted for BCAL3061 by TMHMM2.0 at aa 5-27, 65-87, 92-114 and 159-181 216591015453 HMMPfam hit to PF02325, YGGT family, score 1.9e-13 216591015454 Uncharacterized ACR, COG1993; Region: DUF190; cl00872 216591015455 HMMPfam hit to PF02641, Uncharacterized ACR, COG1993, score 3.4e-07 216591015456 chromosome condensation membrane protein; Provisional; Region: PRK14196 216591015457 HMMPfam hit to PF02537, CrcB-like protein, score 1.8e-31 216591015458 4 probable transmembrane helices predicted for BCAL3063 by TMHMM2.0 at aa 2-24, 39-61, 68-87 and 97-119 216591015459 SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195 216591015460 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591015461 HMMPfam hit to PF02146, Sir2 family, score 1.1e-10 216591015462 Domain of unknown function (DUF4406); Region: DUF4406; pfam14359 216591015463 GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009 216591015464 ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424 216591015465 dimer interface [polypeptide binding]; other site 216591015466 ADP-ribose binding site [chemical binding]; other site 216591015467 active site 216591015468 nudix motif; other site 216591015469 metal binding site [ion binding]; metal-binding site 216591015470 HMMPfam hit to PF00293, NUDIX domain, score 3.7e-11 216591015471 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 216591015472 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591015473 DNA-binding site [nucleotide binding]; DNA binding site 216591015474 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 216591015475 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 0.0026 216591015476 HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 2.1e-16 216591015477 HMMPfam hit to PF08279, HTH domain, score 0.00036 216591015478 PS00894 Bacterial regulatory proteins, deoR family signature. 216591015479 Predicted helix-turn-helix motif with score 1134.000, SD 3.05 at aa 20-41, sequence VLAAELSVQFGVSEDTVRRDLR 216591015480 HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 3.7e-23 216591015481 methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423 216591015482 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591015483 substrate binding site [chemical binding]; other site 216591015484 oxyanion hole (OAH) forming residues; other site 216591015485 trimer interface [polypeptide binding]; other site 216591015486 2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766 216591015487 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 1.1e-11 216591015488 PS00166 Enoyl-CoA hydratase/isomerase signature. 216591015489 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591015490 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591015491 HMMPfam hit to PF02515, CoA-transferase family III, score 5.7e-60 216591015492 benzoate transport; Region: 2A0115; TIGR00895 216591015493 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591015494 putative substrate translocation pore; other site 216591015495 HMMPfam hit to PF00083, Sugar (and other) transporter, score 3.4e-13 216591015496 12 probable transmembrane helices predicted for BCAL3070 by TMHMM2.0 at aa 26-48, 68-90, 102-120, 125-147, 160-182, 187-206, 251-273, 288-310, 317-336, 346-368, 381-403 and 413-431 216591015497 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.6e-23 216591015498 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015499 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015500 PS00217 Sugar transport proteins signature 2. 216591015501 nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233 216591015502 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591015503 The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433 216591015504 putative dimerization interface [polypeptide binding]; other site 216591015505 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 9.5e-24 216591015506 Predicted helix-turn-helix motif with score 1225.000, SD 3.36 at aa 16-37, sequence GNVTHASEALHVAQPAVSQQMR 216591015507 PS00044 Bacterial regulatory proteins, lysR family signature. 216591015508 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.6e-32 216591015509 LysE type translocator; Region: LysE; cl00565 216591015510 6 probable transmembrane helices predicted for BCAL3072 by TMHMM2.0 at aa 5-22, 35-57, 67-89, 121-143, 153-170 and 183-205 216591015511 HMMPfam hit to PF01810, LysE type translocator, score 3.8e-35 216591015512 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948 216591015513 Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188 216591015514 metal binding site [ion binding]; metal-binding site 216591015515 substrate binding pocket [chemical binding]; other site 216591015516 Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450 216591015517 HMMPfam hit to PF05899, Protein of unknown function (DUF861), score 2e-33 216591015518 conserved hypothetical protein (fragment);Probable gene remnant. Similar to the N-terminal region of Burkholderia vietnamiensis G4 hypothetical protein UniProt:Q4BIJ3 (EMBL:AAEH02000019) (358 aa) fasta scores: E()=1.7e-91, 70.370% id in 297 aa 216591015519 BcenGI10 216591015520 Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582 216591015521 INT_SG2, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 2, C-terminal catalytic domain. The CD contains mainly predicted integrase/recombinases and phage-related integrases. Some have N-terminal domains, which show little sequence...; Region: INT_SG2_C; cd01184 216591015522 Int/Topo IB signature motif; other site 216591015523 HMMPfam hit to PF00589, Phage integrase family, score 0.00053 216591015524 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591015525 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591015526 non-specific DNA binding site [nucleotide binding]; other site 216591015527 salt bridge; other site 216591015528 sequence-specific DNA binding site [nucleotide binding]; other site 216591015529 HMMPfam hit to PF01381, Helix-turn-helix, score 2.8e-12 216591015530 Predicted helix-turn-helix motif with score 1151.000, SD 3.11 at aa 25-46, sequence LSQEAFADKVGFARSYFGRVET 216591015531 2 probable transmembrane helices predicted for BCAL3077 by TMHMM2.0 at aa 65-82 and 97-114 216591015532 Domain of unknown function (DUF4309); Region: DUF4309; pfam14172 216591015533 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015534 PS00430 TonB-dependent receptor proteins signature 1. 216591015535 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015536 phosphoribosylaminoimidazole carboxylase; Region: PLN02948 216591015537 Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961 216591015538 Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338 216591015539 catalytic residues [active] 216591015540 catalytic nucleophile [active] 216591015541 HMMPfam hit to PF00239, Resolvase, N terminal domain, score 7.5e-07 216591015542 3 probable transmembrane helices predicted for BCAL3083 by TMHMM2.0 at aa 23-45, 65-87 and 99-121 216591015543 Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285 216591015544 nucleoside/Zn binding site; other site 216591015545 dimer interface [polypeptide binding]; other site 216591015546 catalytic motif [active] 216591015547 HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 3.4e-21 216591015548 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 216591015549 HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822 216591015550 active site 216591015551 homotetramer interface [polypeptide binding]; other site 216591015552 HMMPfam hit to PF00576, Transthyretin precursor (formerly preal, score 5.4e-37 216591015553 HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822 216591015554 active site 216591015555 homotetramer interface [polypeptide binding]; other site 216591015556 HMMPfam hit to PF00576, Transthyretin precursor (formerly preal, score 8.9e-28 216591015557 1 probable transmembrane helix predicted for BCAL3086 by TMHMM2.0 at aa 12-34 216591015558 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591015559 D-galactonate transporter; Region: 2A0114; TIGR00893 216591015560 putative substrate translocation pore; other site 216591015561 12 probable transmembrane helices predicted for BCAL3087 by TMHMM2.0 at aa 26-43, 65-87, 100-122, 126-148, 155-177, 187-209, 256-278, 288-310, 322-344, 349-371, 378-400 and 415-437 216591015562 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.1e-52 216591015563 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591015564 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591015565 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591015566 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_4; cd08463 216591015567 putative substrate binding pocket [chemical binding]; other site 216591015568 putative dimerization interface [polypeptide binding]; other site 216591015569 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.6e-15 216591015570 Predicted helix-turn-helix motif with score 1331.000, SD 3.72 at aa 22-43, sequence RSVSRTAIRMNQSQPALSSALK 216591015571 PS00044 Bacterial regulatory proteins, lysR family signature. 216591015572 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.6e-26 216591015573 OHCU decarboxylase; Region: OHCU_decarbox; pfam09349 216591015574 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591015575 S-adenosylmethionine binding site [chemical binding]; other site 216591015576 HMMPfam hit to PF02390, Putative methyltransferase, score 3.6e-82 216591015577 undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281 216591015578 5 probable transmembrane helices predicted for BCAL3091 by TMHMM2.0 at aa 83-102, 107-129, 187-209, 219-241 and 253-275 216591015579 HMMPfam hit to PF02673, Bacitracin resistance protein BacA, score 3.2e-115 216591015580 1 probable transmembrane helix predicted for BCAL3092 by TMHMM2.0 at aa 12-34 216591015581 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015582 Flagellin N-methylase; Region: FliB; pfam03692 216591015583 HMMPfam hit to PF03692, Uncharacterised protein family (UPF0153), score 8.8e-12 216591015584 coproporphyrinogen III oxidase; Provisional; Region: PRK09249 216591015585 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591015586 FeS/SAM binding site; other site 216591015587 HemN C-terminal domain; Region: HemN_C; pfam06969 216591015588 HMMPfam hit to PF04055, Radical SAM superfamily, score 1.7e-23 216591015589 HMMPfam hit to PF06969, HemN C-terminal region, score 3e-50 216591015590 Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518 216591015591 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591015592 S-adenosylmethionine binding site [chemical binding]; other site 216591015593 HMMPfam hit to PF01135, Protein-L-isoaspartate(D-aspartate) O, score 2.9e-12 216591015594 HMMPfam hit to PF05175, Methyltransferase small domain, score 2.3e-05 216591015595 HMMPfam hit to PF08241, Methyltransferase domain, score 0.00037 216591015596 PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 216591015597 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125 216591015598 active site residue [active] 216591015599 HMMPfam hit to PF00581, Rhodanese-like domain, score 9e-10 216591015600 Periplasmic binding protein; Region: Peripla_BP_6; pfam13458 216591015601 Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355 216591015602 putative ligand binding site [chemical binding]; other site 216591015603 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015604 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 216591015605 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591015606 TM-ABC transporter signature motif; other site 216591015607 8 probable transmembrane helices predicted for BCAL3099 by TMHMM2.0 at aa 242-264, 269-291, 306-325, 338-360, 384-406, 438-460, 475-497 and 504-523 216591015608 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 2.2e-41 216591015609 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015610 ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177 216591015611 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 216591015612 TM-ABC transporter signature motif; other site 216591015613 9 probable transmembrane helices predicted for BCAL3100 by TMHMM2.0 at aa 19-41, 51-73, 78-100, 135-157, 164-183, 213-235, 260-282, 302-324 and 337-359 216591015614 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 3e-30 216591015615 urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411 216591015616 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 216591015617 Walker A/P-loop; other site 216591015618 ATP binding site [chemical binding]; other site 216591015619 Q-loop/lid; other site 216591015620 ABC transporter signature motif; other site 216591015621 Walker B; other site 216591015622 D-loop; other site 216591015623 H-loop/switch region; other site 216591015624 HMMPfam hit to PF00005, ABC transporter, score 9.9e-45 216591015625 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015626 PS00211 ABC transporters family signature. 216591015627 urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410 216591015628 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 216591015629 Walker A/P-loop; other site 216591015630 ATP binding site [chemical binding]; other site 216591015631 Q-loop/lid; other site 216591015632 ABC transporter signature motif; other site 216591015633 Walker B; other site 216591015634 D-loop; other site 216591015635 H-loop/switch region; other site 216591015636 HMMPfam hit to PF00005, ABC transporter, score 6.7e-44 216591015637 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015638 UreD urease accessory protein; Region: UreD; cl00530 216591015639 HMMPfam hit to PF01774, UreD urease accessory protein, score 1.7e-68 216591015640 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015641 Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390 216591015642 alpha-gamma subunit interface [polypeptide binding]; other site 216591015643 beta-gamma subunit interface [polypeptide binding]; other site 216591015644 HMMPfam hit to PF00547, Urease, gamma subunit, score 2.1e-69 216591015645 Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407 216591015646 gamma-beta subunit interface [polypeptide binding]; other site 216591015647 alpha-beta subunit interface [polypeptide binding]; other site 216591015648 HMMPfam hit to PF00699, Urease beta subunit, score 5.6e-65 216591015649 urease subunit alpha; Reviewed; Region: ureC; PRK13207 216591015650 Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375 216591015651 subunit interactions [polypeptide binding]; other site 216591015652 active site 216591015653 flap region; other site 216591015654 HMMPfam hit to PF00449, Urease alpha-subunit, N-terminal domain, score 9.3e-84 216591015655 HMMPfam hit to PF01979, Amidohydrolase family, score 1.6e-97 216591015656 HMMPfam hit to PF07969, Amidohydrolase family, score 0.0014 216591015657 PS01120 Urease nickel ligands signature. 216591015658 PS00145 Urease active site. 216591015659 urease accessory protein UreE; Provisional; Region: ureE; PRK13263 216591015660 UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571 216591015661 dimer interface [polypeptide binding]; other site 216591015662 catalytic residues [active] 216591015663 HMMPfam hit to PF02814, UreE urease accessory protein, N-terminal do, score 3.4e-17 216591015664 HMMPfam hit to PF05194, UreE urease accessory protein, C-terminal do, score 1.3e-44 216591015665 Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830 216591015666 UreF; Region: UreF; pfam01730 216591015667 HMMPfam hit to PF01730, UreF, score 4.7e-39 216591015668 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 216591015669 HMMPfam hit to PF02492, CobW/HypB/UreG, nucleotide-binding domain, score 3.3e-74 216591015670 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015671 3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749 216591015672 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413 216591015673 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 216591015674 HMMPfam hit to PF04413, 3-Deoxy-D-manno-octulosonic-acid tran, score 1.5e-79 216591015675 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase; Region: Kdo_hydroxy; pfam11004 216591015676 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859 216591015677 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 216591015678 putative active site [active] 216591015679 HMMPfam hit to PF01075, Glycosyltransferase family, score 2.9e-51 216591015680 Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109 216591015681 The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089 216591015682 active site 216591015683 substrate binding site [chemical binding]; other site 216591015684 metal binding site [ion binding]; metal-binding site 216591015685 HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-, score 2e-15 216591015686 HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 9.6e-44 216591015687 HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 1.4e-45 216591015688 HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 4e-44 216591015689 Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326 216591015690 12 probable transmembrane helices predicted for BCAL3114 by TMHMM2.0 at aa 20-42, 52-74, 87-109, 119-141, 154-176, 181-200, 216-238, 267-286, 299-321, 336-358, 365-385 and 390-412 216591015691 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 216591015692 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 216591015693 active site 216591015694 HMMPfam hit to PF00535, Glycosyl transferase family, score 2.9e-09 216591015695 This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808 216591015696 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591015697 putative ADP-binding pocket [chemical binding]; other site 216591015698 HMMPfam hit to PF00534, Glycosyl transferases group, score 6.8e-33 216591015699 UDP-glucose 4-epimerase; Region: PLN02240 216591015700 UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247 216591015701 NAD binding site [chemical binding]; other site 216591015702 homodimer interface [polypeptide binding]; other site 216591015703 active site 216591015704 substrate binding site [chemical binding]; other site 216591015705 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.9e-05 216591015706 HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.0015 216591015707 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 1.2e-77 216591015708 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.00034 216591015709 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 1.5e-07 216591015710 HMMPfam hit to PF07993, Male sterility protein, score 0.00024 216591015711 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472 216591015712 This subfamily is composed of uncharacterized bacterial glycosyltransferases in the MraY-like family. This family contains both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases, which...; Region: GT_MraY_like; cd06912 216591015713 Mg++ binding site [ion binding]; other site 216591015714 putative catalytic motif [active] 216591015715 11 probable transmembrane helices predicted for BCAL3118 by TMHMM2.0 at aa 5-24, 45-64, 69-91, 104-123, 133-155, 160-182, 186-205, 210-232, 242-261, 306-325 and 329-351 216591015716 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015717 HMMPfam hit to PF00953, Glycosyl transferase family, score 2.7e-17 216591015718 Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086 216591015719 CoA binding domain; Region: CoA_binding; cl17356 216591015720 UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237 216591015721 NAD(P) binding site [chemical binding]; other site 216591015722 homodimer interface [polypeptide binding]; other site 216591015723 substrate binding site [chemical binding]; other site 216591015724 active site 216591015725 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 1.3e-188 216591015726 HMMPfam hit to PF04321, RmlD substrate binding domain, score 4.5e-05 216591015727 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 3.6e-06 216591015728 HMMPfam hit to PF07993, Male sterility protein, score 0.00018 216591015729 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 1.6e-08 216591015730 HMMPfam hit to PF02629, CoA binding domain, score 0.054 216591015731 5 probable transmembrane helices predicted for BCAL3119 by TMHMM2.0 at aa 7-29, 44-66, 78-100, 105-127 and 134-156 216591015732 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472 216591015733 The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854 216591015734 Mg++ binding site [ion binding]; other site 216591015735 putative catalytic motif [active] 216591015736 putative substrate binding site [chemical binding]; other site 216591015737 10 probable transmembrane helices predicted for BCAL3120 by TMHMM2.0 at aa 13-35, 57-79, 100-118, 122-144, 149-171, 176-193, 200-222, 226-248, 274-296 and 306-323 216591015738 HMMPfam hit to PF00953, Glycosyl transferase family, score 3.7e-11 216591015739 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 216591015740 UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs; Region: UDP_G4E_4_SDR_e; cd05232 216591015741 putative NAD(P) binding site [chemical binding]; other site 216591015742 active site 216591015743 putative substrate binding site [chemical binding]; other site 216591015744 HMMPfam hit to PF04321, RmlD substrate binding domain, score 2.8e-09 216591015745 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 6.6e-14 216591015746 HMMPfam hit to PF05368, NmrA-like family, score 0.0012 216591015747 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.00096 216591015748 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 1.6e-44 216591015749 HMMPfam hit to PF07993, Male sterility protein, score 4.6e-11 216591015750 Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186 216591015751 Predicted glycosyltransferases [General function prediction only]; Region: COG1216 216591015752 Probable Catalytic site; other site 216591015753 metal-binding site 216591015754 HMMPfam hit to PF00535, Glycosyl transferase family, score 5.3e-09 216591015755 Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360 216591015756 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570 216591015757 putative trimer interface [polypeptide binding]; other site 216591015758 putative CoA binding site [chemical binding]; other site 216591015759 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 25 216591015760 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 14 216591015761 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 7.3 216591015762 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 216591015763 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 216591015764 active site 216591015765 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 216591015766 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 216591015767 active site 216591015768 HMMPfam hit to PF00535, Glycosyl transferase family, score 4.7e-34 216591015769 HMMPfam hit to PF00535, Glycosyl transferase family, score 3.8e-33 216591015770 CDS is interrupted by an IS element insertion after codon 84. Previously sequenced as Burkholderia cenocepacia WbcE glycosyltransferase UniProt:Q6GVJ4_9BURK (EMBL:AY633623) (456 aa) fasta scores: E()=4.4e-181, 100.000% id in 456 aa 216591015771 HMMPfam hit to PF00534, Glycosyl transferases group, score 4.5e-08 216591015772 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 216591015773 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 216591015774 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 216591015775 Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586 216591015776 HMMPfam hit to PF01609, Transposase DDE domain, score 3.6e-32 216591015777 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 216591015778 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 216591015779 active site 216591015780 HMMPfam hit to PF00535, Glycosyl transferase family, score 8e-41 216591015781 DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041 216591015782 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 216591015783 inhibitor-cofactor binding pocket; inhibition site 216591015784 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591015785 catalytic residue [active] 216591015786 HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 4e-89 216591015787 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0025 216591015788 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015789 ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134 216591015790 ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220 216591015791 Walker A/P-loop; other site 216591015792 ATP binding site [chemical binding]; other site 216591015793 Q-loop/lid; other site 216591015794 ABC transporter signature motif; other site 216591015795 Walker B; other site 216591015796 D-loop; other site 216591015797 H-loop/switch region; other site 216591015798 C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147 216591015799 putative carbohydrate binding site [chemical binding]; other site 216591015800 HMMPfam hit to PF00005, ABC transporter, score 2.2e-42 216591015801 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015802 ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682 216591015803 ABC-2 type transporter; Region: ABC2_membrane; pfam01061 216591015804 6 probable transmembrane helices predicted for BCAL3131 by TMHMM2.0 at aa 37-59, 74-96, 117-139, 149-171, 184-206 and 236-258 216591015805 HMMPfam hit to PF01061, ABC-2 type transporter, score 6.9e-40 216591015806 RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321 216591015807 dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254 216591015808 NADP binding site [chemical binding]; other site 216591015809 active site 216591015810 putative substrate binding site [chemical binding]; other site 216591015811 HMMPfam hit to PF04321, RmlD substrate binding domain, score 8.2e-141 216591015812 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 0.00062 216591015813 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 2.2e-13 216591015814 HMMPfam hit to PF07993, Male sterility protein, score 7e-05 216591015815 dTDP-4-dehydrorhamnose 3,5-epimerase; Region: rmlC; TIGR01221 216591015816 HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose 3,5-epimerase, score 9.5e-109 216591015817 G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538 216591015818 glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207 216591015819 substrate binding site; other site 216591015820 tetramer interface; other site 216591015821 HMMPfam hit to PF00483, Nucleotidyl transferase, score 2.6e-109 216591015822 dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088 216591015823 dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246 216591015824 NAD binding site [chemical binding]; other site 216591015825 substrate binding site [chemical binding]; other site 216591015826 homodimer interface [polypeptide binding]; other site 216591015827 active site 216591015828 HMMPfam hit to PF04321, RmlD substrate binding domain, score 2.6e-07 216591015829 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 1.2e-07 216591015830 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.0015 216591015831 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 3.6e-86 216591015832 HMMPfam hit to PF07993, Male sterility protein, score 6.5e-07 216591015833 diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166 216591015834 Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422 216591015835 active site 216591015836 metal binding site [ion binding]; metal-binding site 216591015837 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 8.9e-13 216591015838 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204 216591015839 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 216591015840 putative acyl-acceptor binding pocket; other site 216591015841 PS00017 ATP/GTP-binding site motif A (P-loop). 216591015842 HMMPfam hit to PF01553, Acyltransferase, score 2.9e-35 216591015843 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015844 dihydroorotase; Provisional; Region: PRK07627 216591015845 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 216591015846 Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317 216591015847 active site 216591015848 HMMPfam hit to PF01979, Amidohydrolase family, score 0.0074 216591015849 aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856 216591015850 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 216591015851 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 216591015852 HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, As, score 3.6e-22 216591015853 HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, ca, score 7e-31 216591015854 PS00097 Aspartate and ornithine carbamoyltransferases signature. 216591015855 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 216591015856 active site 216591015857 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.6e-10 216591015858 Holliday junction resolvase-like protein; Reviewed; Region: PRK00109 216591015859 HMMPfam hit to PF03652, Uncharacterised protein family (UPF0081), score 6.9e-44 216591015860 hypothetical protein; Validated; Region: PRK00228 216591015861 HMMPfam hit to PF02622, Uncharacterized ACR, COG1678, score 1.5e-94 216591015862 Rubredoxin [Energy production and conversion]; Region: COG1773 216591015863 Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730 216591015864 iron binding site [ion binding]; other site 216591015865 HMMPfam hit to PF00301, Rubredoxin, score 4.1e-25 216591015866 PS00202 Rubredoxin signature. 216591015867 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169 216591015868 dimer interface [polypeptide binding]; other site 216591015869 substrate binding site [chemical binding]; other site 216591015870 ATP binding site [chemical binding]; other site 216591015871 HMMPfam hit to PF08543, Phosphomethylpyrimidine kinase, score 2.3e-55 216591015872 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015873 chaperonin GroEL; Reviewed; Region: groEL; PRK12849 216591015874 GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344 216591015875 ring oligomerisation interface [polypeptide binding]; other site 216591015876 ATP/Mg binding site [chemical binding]; other site 216591015877 stacking interactions; other site 216591015878 hinge regions; other site 216591015879 HMMPfam hit to PF00118, TCP-1/cpn60 chaperonin family, score 1.5e-194 216591015880 PS00296 Chaperonins cpn60 signature. 216591015881 Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320 216591015882 oligomerisation interface [polypeptide binding]; other site 216591015883 mobile loop; other site 216591015884 roof hairpin; other site 216591015885 HMMPfam hit to PF00166, Chaperonin 10 Kd subunit, score 1.2e-51 216591015886 PS00681 Chaperonins cpn10 signature. 216591015887 Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_6; cd07824 216591015888 putative hydrophobic ligand binding site [chemical binding]; other site 216591015889 Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834 216591015890 nitrous-oxide reductase, Sec-dependent; Region: nitrous_NosZ_Gp; TIGR04246 216591015891 Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662 216591015892 1 probable transmembrane helix predicted for BCAL3151 by TMHMM2.0 at aa 86-108 216591015893 RNA polymerase sigma factor; Provisional; Region: PRK12511 216591015894 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591015895 HMMPfam hit to PF04545, Sigma-70, region, score 3.3e-13 216591015896 HMMPfam hit to PF08281, Sigma-70, region, score 9.1e-19 216591015897 Predicted helix-turn-helix motif with score 1265.000, SD 3.50 at aa 122-143, sequence LSYRDAAQVLGVPVGTVMSRLA 216591015898 HMMPfam hit to PF04542, Sigma-70 region, score 5.5e-09 216591015899 Secreted repeat of unknown function; Region: Lipoprotein_15; pfam03640 216591015900 Secreted repeat of unknown function; Region: Lipoprotein_15; pfam03640 216591015901 HMMPfam hit to PF03640, Secreted repeat of unknown function, score 4.3e-18 216591015902 HMMPfam hit to PF03640, Secreted repeat of unknown function, score 3.9e-12 216591015903 1 probable transmembrane helix predicted for BCAL3154 by TMHMM2.0 at aa 29-51 216591015904 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591015905 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591015906 hydroxyglutarate oxidase; Provisional; Region: PRK11728 216591015907 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 8.5e-86 216591015908 PS00192 Cytochrome b/b6 heme-ligand signature. 216591015909 lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096 216591015910 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591015911 substrate binding pocket [chemical binding]; other site 216591015912 membrane-bound complex binding site; other site 216591015913 hinge residues; other site 216591015914 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 5e-84 216591015915 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591015916 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015917 Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; Region: COG2423 216591015918 ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400 216591015919 HMMPfam hit to PF02423, Ornithine cyclodeaminase/mu-crystalli, score 2.5e-11 216591015920 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964 216591015921 YheO-like PAS domain; Region: PAS_6; pfam08348 216591015922 HTH domain; Region: HTH_22; pfam13309 216591015923 HMMPfam hit to PF08348, YheO-like protein, score 3.3e-49 216591015924 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761 216591015925 DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024 216591015926 catalytic residues [active] 216591015927 HMMPfam hit to PF01323, DSBA-like thioredoxin domain, score 1.1e-45 216591015928 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591015929 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591015930 putative substrate translocation pore; other site 216591015931 14 probable transmembrane helices predicted for BCAL3160 by TMHMM2.0 at aa 12-34, 49-68, 80-102, 112-131, 138-160, 166-188, 200-222, 227-249, 270-292, 302-324, 331-353, 363-385, 398-420 and 440-462 216591015932 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.7e-57 216591015933 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015934 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015935 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015936 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 216591015937 7 probable transmembrane helices predicted for BCAL3161 by TMHMM2.0 at aa 21-43, 53-75, 95-117, 127-145, 174-196, 234-256 and 263-280 216591015938 HMMPfam hit to PF01925, Domain of unknown function DUF81, score 1.3e-25 216591015939 Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403 216591015940 active site 216591015941 NTP binding site [chemical binding]; other site 216591015942 metal binding triad [ion binding]; metal-binding site 216591015943 antibiotic binding site [chemical binding]; other site 216591015944 HMMPfam hit to PF01909, Nucleotidyltransferase domain, score 0.00016 216591015945 Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939 216591015946 Serine carboxypeptidase; Region: Peptidase_S10; cl08270 216591015947 HMMPfam hit to PF00450, Serine carboxypeptidase, score 5.3e-06 216591015948 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015949 1 probable transmembrane helix predicted for BCAL3164 by TMHMM2.0 at aa 12-34 216591015950 3HB-oligomer hydrolase (3HBOH); Region: 3HBOH; pfam10605 216591015951 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015952 BON domain; Region: BON; pfam04972 216591015953 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 5.5e-13 216591015954 TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: Imp; COG2358 216591015955 TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122 216591015956 2 probable transmembrane helices predicted for BCAL3167 by TMHMM2.0 at aa 21-43 and 349-371 216591015957 DsbA family, 2-hydroxychromene-2-carboxylate (HCCA) isomerase subfamily; HCCA isomerase is a glutathione (GSH) dependent enzyme involved in the naphthalene catabolic pathway. It converts HCCA, a hemiketal formed spontaneously after ring cleavage of 1; Region: DsbA_HCCA_Iso; cd03022 216591015958 DSBA-like thioredoxin domain; Region: DSBA; pfam01323 216591015959 putative catalytic residue [active] 216591015960 HMMPfam hit to PF01323, DSBA-like thioredoxin domain, score 4.8e-14 216591015961 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591015962 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591015963 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591015964 dimerization interface [polypeptide binding]; other site 216591015965 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.5e-17 216591015966 Predicted helix-turn-helix motif with score 1376.000, SD 3.87 at aa 24-45, sequence RSVTQAALRLNQTQPAISTALR 216591015967 PS00044 Bacterial regulatory proteins, lysR family signature. 216591015968 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.2e-21 216591015969 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460 216591015970 xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964 216591015971 XdhC Rossmann domain; Region: XdhC_C; pfam13478 216591015972 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591015973 xanthine dehydrogenase, molybdopterin binding subunit; Region: xanthine_xdhB; TIGR02965 216591015974 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 216591015975 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591015976 HMMPfam hit to PF02738, Aldehyde oxidase and xanthine dehydroge, score 3.7e-203 216591015977 HMMPfam hit to PF01315, Aldehyde oxidase and xanthine dehydroge, score 5.9e-46 216591015978 xanthine dehydrogenase, small subunit; Region: xanthine_xdhA; TIGR02963 216591015979 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591015980 catalytic loop [active] 216591015981 iron binding site [ion binding]; other site 216591015982 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 216591015983 CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450 216591015984 HMMPfam hit to PF03450, CO dehydrogenase flavoprotein C-termina, score 9.4e-24 216591015985 HMMPfam hit to PF00941, FAD binding domain in molybdopterin deh, score 2.9e-66 216591015986 HMMPfam hit to PF01799, [2Fe-2S] binding domain, score 1.6e-42 216591015987 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591015988 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 0.012 216591015989 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591015990 major facilitator superfamily transporter; Provisional; Region: PRK05122 216591015991 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591015992 12 probable transmembrane helices predicted for BCAL3174 by TMHMM2.0 at aa 2-21, 31-53, 66-88, 103-125, 132-154, 159-181, 202-224, 234-253, 260-282, 292-314, 321-343 and 353-372 216591015993 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.8e-24 216591015994 EamA-like transporter family; Region: EamA; pfam00892 216591015995 EamA-like transporter family; Region: EamA; cl17759 216591015996 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.2e-10 216591015997 10 probable transmembrane helices predicted for BCAL3175 by TMHMM2.0 at aa 5-27, 32-51, 64-86, 90-112, 119-137, 147-169, 182-204, 214-236, 243-261 and 266-285 216591015998 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.2e-25 216591015999 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016000 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591016001 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591016002 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.6e-07 216591016003 Predicted helix-turn-helix motif with score 1247.000, SD 3.43 at aa 223-244, sequence LTLGELAEVAALSEYHFSRMFR 216591016004 PS00041 Bacterial regulatory proteins, araC family signature. 216591016005 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.2e-10 216591016006 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016007 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075 216591016008 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591016009 catalytic residue [active] 216591016010 HMMPfam hit to PF00266, Aminotransferase class-V, score 8e-12 216591016011 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 216591016012 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591016013 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591016014 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591016015 putative effector binding pocket; other site 216591016016 dimerization interface [polypeptide binding]; other site 216591016017 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.7e-14 216591016018 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.8e-47 216591016019 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 216591016020 D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183 216591016021 putative ligand binding site [chemical binding]; other site 216591016022 putative NAD binding site [chemical binding]; other site 216591016023 catalytic site [active] 216591016024 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 4.3e-40 216591016025 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 9.5e-80 216591016026 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016027 PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 216591016028 PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 216591016029 Subfamily of the nitroreductase family that includes BluB protein in Rhodobacter capsulatus is involved in the conversion of cobinamide to cobalamin in Cobalamin (vitamin B12) biosynthesis. Nitroreductases typically reduce their substrates by using NAD(P)...; Region: BluB; cd02145 216591016030 putative FMN binding site [chemical binding]; other site 216591016031 HMMPfam hit to PF00881, Nitroreductase family, score 7.1e-48 216591016032 MFS transport protein AraJ; Provisional; Region: PRK10091 216591016033 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591016034 putative substrate translocation pore; other site 216591016035 12 probable transmembrane helices predicted for BCAL3181 by TMHMM2.0 at aa 7-29, 39-61, 73-95, 99-121, 128-150, 160-179, 200-222, 237-259, 266-285, 289-311, 332-354 and 358-377 216591016036 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 8.9e-50 216591016037 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591016038 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591016039 putative substrate translocation pore; other site 216591016040 12 probable transmembrane helices predicted for BCAL3182 by TMHMM2.0 at aa 12-34, 44-66, 75-93, 98-120, 133-155, 160-179, 200-222, 237-259, 271-289, 293-315, 322-344 and 354-376 216591016041 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.3e-28 216591016042 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016043 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016044 fumarylacetoacetase; Region: PLN02856 216591016045 Domain of unknown function (DUF1969); Region: DUF1969; pfam09298 216591016046 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 216591016047 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 2e-85 216591016048 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016049 homogentisate 1,2-dioxygenase; Provisional; Region: PRK05341 216591016050 HMMPfam hit to PF04209, homogentisate 1,2-dioxygenase, score 7.9e-276 216591016051 benzoate transport; Region: 2A0115; TIGR00895 216591016052 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591016053 putative substrate translocation pore; other site 216591016054 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591016055 putative substrate translocation pore; other site 216591016056 HMMPfam hit to PF00083, Sugar (and other) transporter, score 2.1e-06 216591016057 12 probable transmembrane helices predicted for BCAL3185 by TMHMM2.0 at aa 19-41, 56-78, 85-107, 111-133, 145-167, 172-194, 254-276, 286-308, 315-337, 342-364, 377-399 and 409-431 216591016058 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.7e-53 216591016059 PS00217 Sugar transport proteins signature 2. 216591016060 PS00216 Sugar transport proteins signature 1. 216591016061 Protein of unknown function (DUF2783); Region: DUF2783; pfam10932 216591016062 FAD-dependent oxidoreductase; Provisional; Region: PRK08132 216591016063 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591016064 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591016065 HMMPfam hit to PF01494, FAD binding domain, score 2.8e-57 216591016066 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.1e-05 216591016067 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290 216591016068 HMMPfam hit to PF00563, EAL domain, score 0.00057 216591016069 Uncharacterized conserved protein [Function unknown]; Region: COG3791 216591016070 HMMPfam hit to PF04828, Protein of unknown function (DUF636), score 3.8e-24 216591016071 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591016072 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 216591016073 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591016074 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 0.00027 216591016075 Predicted helix-turn-helix motif with score 1019.000, SD 2.66 at aa 37-58, sequence LGNRDFAERTGLPKATVNRLAY 216591016076 Glutaryl-CoA dehydrogenase; Region: GCD; cd01151 216591016077 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591016078 FAD binding site [chemical binding]; other site 216591016079 substrate binding pocket [chemical binding]; other site 216591016080 catalytic base [active] 216591016081 HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal doma, score 2.2e-25 216591016082 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 3.2e-25 216591016083 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 4.7e-33 216591016084 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 2.6e-05 216591016085 PS00073 Acyl-CoA dehydrogenases signature 2. 216591016086 Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450 216591016087 Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016 216591016088 dimer interface [polypeptide binding]; other site 216591016089 decamer (pentamer of dimers) interface [polypeptide binding]; other site 216591016090 catalytic triad [active] 216591016091 HMMPfam hit to PF00578, AhpC/TSA family, score 6.4e-87 216591016092 HMMPfam hit to PF08534, Redoxin, score 1.2e-07 216591016093 Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957 216591016094 HMMPfam hit to PF05957, Bacterial protein of unknown function (DUF88, score 6.6e-40 216591016095 Predicted membrane protein [Function unknown]; Region: COG5393 216591016096 2 probable transmembrane helices predicted for BCAL3194 by TMHMM2.0 at aa 47-69 and 79-98 216591016097 Protein of unknown function (DUF3318); Region: DUF3318; pfam11780 216591016098 Probable gene remnant. CDS contains a nonsense mutation (amber) after codon 59. Similar to Burkholderia pseudomallei putative fimbrial protein UniProt:Q63RC0 (EMBL:BX571965) (150 aa) fasta scores: E()=0.018, 33.628% id in 113 aa 216591016099 transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464 216591016100 ATP cone domain; Region: ATP-cone; pfam03477 216591016101 HMMPfam hit to PF03477, ATP cone domain, score 3.1e-28 216591016102 serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011 216591016103 Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378 216591016104 dimer interface [polypeptide binding]; other site 216591016105 active site 216591016106 glycine-pyridoxal phosphate binding site [chemical binding]; other site 216591016107 folate binding site [chemical binding]; other site 216591016108 HMMPfam hit to PF01276, Orn/Lys/Arg decarboxylase, major doma, score 0.074 216591016109 HMMPfam hit to PF00155, Aminotransferase class I and II, score 4.3e-05 216591016110 HMMPfam hit to PF00464, Serine hydroxymethyltransferase, score 3.5e-260 216591016111 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0003 216591016112 PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 216591016113 malonic semialdehyde reductase; Provisional; Region: PRK10538 216591016114 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591016115 NAD(P) binding site [chemical binding]; other site 216591016116 active site 216591016117 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.8e-24 216591016118 PS00061 Short-chain dehydrogenases/reductases family signature. 216591016119 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 216591016120 active site 216591016121 HMMPfam hit to PF03061, Thioesterase superfamily, score 6e-22 216591016122 TolQ protein; Region: tolQ; TIGR02796 216591016123 3 probable transmembrane helices predicted for BCAL3200 by TMHMM2.0 at aa 20-39, 131-153 and 173-195 216591016124 HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 1.7e-50 216591016125 Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848 216591016126 TolR protein; Region: tolR; TIGR02801 216591016127 HMMPfam hit to PF02472, Biopolymer transport protein ExbD/TolR, score 4.4e-22 216591016128 1 probable transmembrane helix predicted for BCAL3201 by TMHMM2.0 at aa 24-46 216591016129 TolA protein; Region: tolA_full; TIGR02794 216591016130 TonB C terminal; Region: TonB_2; pfam13103 216591016131 HMMPfam hit to PF06519, TolA protein, score 1.2e-08 216591016132 1 probable transmembrane helix predicted for BCAL3202 by TMHMM2.0 at aa 21-43 216591016133 translocation protein TolB; Provisional; Region: tolB; PRK02889 216591016134 TolB amino-terminal domain; Region: TolB_N; pfam04052 216591016135 WD40-like Beta Propeller Repeat; Region: PD40; pfam07676 216591016136 WD40-like Beta Propeller Repeat; Region: PD40; pfam07676 216591016137 HMMPfam hit to PF04052, TolB amino-terminal domain, score 7.9e-29 216591016138 HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.015 216591016139 HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.12 216591016140 HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 4.6e-11 216591016141 HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 1.1e-08 216591016142 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 216591016143 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591016144 ligand binding site [chemical binding]; other site 216591016145 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016146 HMMPfam hit to PF00691, OmpA family, score 2.7e-40 216591016147 PS01068 OmpA-like domain. 216591016148 tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795 216591016149 Tetratricopeptide repeat; Region: TPR_6; pfam13174 216591016150 1 probable transmembrane helix predicted for BCAL3205 by TMHMM2.0 at aa 7-29 216591016151 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591016152 non-specific DNA binding site [nucleotide binding]; other site 216591016153 salt bridge; other site 216591016154 sequence-specific DNA binding site [nucleotide binding]; other site 216591016155 Predicted helix-turn-helix motif with score 1069.000, SD 2.83 at aa 17-38, sequence LNQTELAALGGVQKHAQFQYEK 216591016156 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591016157 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591016158 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591016159 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-31 216591016160 Protein of unknown function (DUF3018); Region: DUF3018; pfam11455 216591016161 PemK-like protein; Region: PemK; pfam02452 216591016162 type IV secretion system T-DNA border endonuclease VirD2; Provisional; Region: PRK13863 216591016163 yiaA/B two helix domain; Region: YiaAB; pfam05360 216591016164 yiaA/B two helix domain; Region: YiaAB; pfam05360 216591016165 HMMPfam hit to PF05360, yiaA/B two helix domain, score 9.1e-20 216591016166 4 probable transmembrane helices predicted for BCAL3212 by TMHMM2.0 at aa 11-33, 43-62, 74-96 and 106-123 216591016167 HMMPfam hit to PF05360, yiaA/B two helix domain, score 9.2e-20 216591016168 Cupin; Region: Cupin_6; pfam12852 216591016169 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591016170 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591016171 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1e-07 216591016172 Predicted helix-turn-helix motif with score 1052.000, SD 2.77 at aa 227-248, sequence WTVESLGAAAAMSRATYARHFR 216591016173 Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627 216591016174 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 6.2e-25 216591016175 ergothioneine biosynthesis protein EgtC; Region: TIGR03442 216591016176 Glutamine amidotransferases class-II (Gn-AT)_YafJ-type. YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea. YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908 216591016177 putative active site [active] 216591016178 putative dimer interface [polypeptide binding]; other site 216591016179 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 0.00031 216591016180 Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027 216591016181 ligand-binding site [chemical binding]; other site 216591016182 HMMPfam hit to PF01583, Adenylylsulphate kinase, score 1.2e-88 216591016183 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016184 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591016185 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 0.00015 216591016186 pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825 216591016187 KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454 216591016188 substrate-cofactor binding pocket; other site 216591016189 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591016190 catalytic residue [active] 216591016191 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.1e-49 216591016192 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016193 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: PRK13187 216591016194 UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331 216591016195 HMMPfam hit to PF03331, UDP-3-O-acyl N-acetylglycosamine deacetylase, score 2.4e-37 216591016196 Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321 216591016197 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 216591016198 active site 216591016199 Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827 216591016200 Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826 216591016201 Methyltransferase domain; Region: Methyltransf_23; pfam13489 216591016202 Methyltransferase domain; Region: Methyltransf_12; pfam08242 216591016203 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591016204 enoyl reductase of polyketide synthase; Region: enoyl_red; cd05195 216591016205 Enoylreductase; Region: PKS_ER; smart00829 216591016206 NAD(P) binding site [chemical binding]; other site 216591016207 beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 2, complex (x); Region: KR_2_FAS_SDR_x; cd08955 216591016208 KR domain; Region: KR; pfam08659 216591016209 putative NADP binding site [chemical binding]; other site 216591016210 active site 216591016211 Phosphopantetheine attachment site; Region: PKS_PP; smart00823 216591016212 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 6e-08 216591016213 PS00012 Phosphopantetheine attachment site. 216591016214 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.5e-73 216591016215 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 5.3e-38 216591016216 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like doma, score 2.3e-08 216591016217 HMMPfam hit to PF08242, Methyltransferase domain, score 1.6e-06 216591016218 HMMPfam hit to PF00698, Acyl transferase domain, score 4.1e-79 216591016219 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 6.2e-75 216591016220 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 6.8e-122 216591016221 PS00606 Beta-ketoacyl synthases active site. 216591016222 Sulfatase; Region: Sulfatase; cl17466 216591016223 HMMPfam hit to PF00884, Sulfatase, score 1.3e-46 216591016224 3 probable transmembrane helices predicted for BCAL3221 by TMHMM2.0 at aa 33-55, 100-122 and 135-154 216591016225 short chain dehydrogenase; Provisional; Region: PRK08251 216591016226 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591016227 NAD(P) binding site [chemical binding]; other site 216591016228 active site 216591016229 HMMPfam hit to PF00106, short chain dehydrogenase, score 6.3e-16 216591016230 PS00061 Short-chain dehydrogenases/reductases family signature. 216591016231 CDS is interrupted by IS element insertion after codon 92. Similar to Burkholderia pseudomallei (Pseudomonas pseudomallei) putative capsule polysaccharide biosynthesis/export protein WcbO UniProt:Q63R81 (EMBL:BX571965) (400 aa) fasta scores: E()=1.3e-121, 72.431% id in 399 aa 216591016232 HMMPfam hit to PF05159, Capsule polysaccharide biosynthesis pro, score 5e-105 216591016233 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591016234 Transposase; Region: HTH_Tnp_1; pfam01527 216591016235 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591016236 GAGA binding protein-like family; Region: GAGA_bind; pfam06217 216591016237 GAGA binding protein-like family; Region: GAGA_bind; pfam06217 216591016238 GAGA binding protein-like family; Region: GAGA_bind; pfam06217 216591016239 PS01067 Protein secE/sec61-gamma signature. 216591016240 Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900 216591016241 FkbH-like domain; Region: FkbH; TIGR01686 216591016242 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591016243 active site 216591016244 motif I; other site 216591016245 motif II; other site 216591016246 GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472 216591016247 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 216591016248 Predicted glycosyltransferases [General function prediction only]; Region: COG1216 216591016249 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 216591016250 active site 216591016251 HMMPfam hit to PF00535, Glycosyl transferase family, score 1.5e-09 216591016252 UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562 216591016253 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 216591016254 UDP-galactopyranose mutase; Region: GLF; pfam03275 216591016255 HMMPfam hit to PF03275, UDP-galactopyranose mutase, score 4.3e-106 216591016256 Transposase; Region: HTH_Tnp_1; pfam01527 216591016257 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591016258 HMMPfam hit to PF01527, Transposase, score 4.1e-08 216591016259 IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717 216591016260 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591016261 HMMPfam hit to PF05717, IS66 Orf2 like protein, score 5.2e-37 216591016262 Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007 216591016263 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591016264 putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005 216591016265 Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050 216591016266 IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817 216591016267 HMMPfam hit to PF03050, Transposase IS66 family, score 1.6e-73 216591016268 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591016269 Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692 216591016270 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 216591016271 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 216591016272 active site 216591016273 HMMPfam hit to PF00535, Glycosyl transferase family, score 9.9e-41 216591016274 PS00327 Bacterial rhodopsins retinal binding site. 216591016275 ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220 216591016276 Vi polysaccharide export ATP-binding protein VexC; Provisional; Region: PRK15177 216591016277 Walker A/P-loop; other site 216591016278 ATP binding site [chemical binding]; other site 216591016279 Q-loop/lid; other site 216591016280 ABC transporter signature motif; other site 216591016281 Walker B; other site 216591016282 D-loop; other site 216591016283 H-loop/switch region; other site 216591016284 HMMPfam hit to PF00005, ABC transporter, score 2.1e-17 216591016285 PS00211 ABC transporters family signature. 216591016286 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016287 ABC-2 type transporter; Region: ABC2_membrane; cl17235 216591016288 6 probable transmembrane helices predicted for BCAL3241 by TMHMM2.0 at aa 37-59, 64-83, 117-139, 149-171, 183-205 and 236-258 216591016289 HMMPfam hit to PF01061, ABC-2 type transporter, score 0.0003 216591016290 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591016291 polysaccharide export inner-membrane protein, BexC/CtrB/KpsE family; Region: BexC_CtrB_KpsE; TIGR01010 216591016292 2 probable transmembrane helices predicted for BCAL3242 by TMHMM2.0 at aa 7-29 and 340-362 216591016293 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591016294 polysaccharide export protein Wza; Provisional; Region: PRK15078 216591016295 Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563 216591016296 HMMPfam hit to PF02563, Polysaccharide biosynthesis/export protei, score 7e-14 216591016297 This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809 216591016298 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591016299 HMMPfam hit to PF00534, Glycosyl transferases group, score 3.8e-09 216591016300 Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159 216591016301 Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159 216591016302 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591016303 HMMPfam hit to PF05159, Capsule polysaccharide biosynthesis pro, score 5.2e-106 216591016304 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479 216591016305 GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509 216591016306 Substrate binding site; other site 216591016307 Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050 216591016308 HMMPfam hit to PF00483, Nucleotidyl transferase, score 5.7e-110 216591016309 HMMPfam hit to PF01050, Mannose-6-phosphate isomerase, score 1.1e-122 216591016310 HMMPfam hit to PF07883, Cupin domain, score 2.7e-10 216591016311 Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668 216591016312 Mechanosensitive ion channel; Region: MS_channel; pfam00924 216591016313 3 probable transmembrane helices predicted for BCAL3247 by TMHMM2.0 at aa 10-32, 61-83 and 88-110 216591016314 HMMPfam hit to PF00924, Mechanosensitive ion channel, score 5e-37 216591016315 HMMPfam hit to PF00665, Integrase core domain, score 3.8e-43 216591016316 CDS is interrupted by IS element insertion after codon 231. Similar to Ralstonia solanacearum (Pseudomonas solanacearum) ISRso8-transposase OrfB protein. UniProt:Q8XEM0 (EMBL:AL646052) (296 aa) fasta scores: E()=4.5e-110, 87.162% id in 296 aa 216591016317 HMMPfam hit to PF00665, Integrase core domain, score 1.3e-44 216591016318 Transposase, Mutator family; Region: Transposase_mut; pfam00872 216591016319 MULE transposase domain; Region: MULE; pfam10551 216591016320 HMMPfam hit to PF00872, Transposase, Mutator family, score 3.1e-164 216591016321 PS01007 Transposases, Mutator family, signature. 216591016322 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591016323 Transposase; Region: HTH_Tnp_1; pfam01527 216591016324 HMMPfam hit to PF01527, Transposase, score 1.6e-20 216591016325 HMMPfam hit to PF04218, CENP-B N-terminal DNA-binding domain, score 0.00072 216591016326 Predicted helix-turn-helix motif with score 1874.000, SD 5.57 at aa 25-46, sequence QRVAVVARELGISEQTLRNWVK 216591016327 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591016328 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591016329 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591016330 HMMPfam hit to PF01527, Transposase, score 0.003 216591016331 SNARE associated Golgi protein; Region: SNARE_assoc; cl00429 216591016332 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 216591016333 5 probable transmembrane helices predicted for BCAL3255 by TMHMM2.0 at aa 27-49, 69-91, 130-149, 159-181 and 188-210 216591016334 DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095 216591016335 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591016336 ATP binding site [chemical binding]; other site 216591016337 Mg2+ binding site [ion binding]; other site 216591016338 G-X-G motif; other site 216591016339 MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL. EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482 216591016340 ATP binding site [chemical binding]; other site 216591016341 MutL C terminal dimerisation domain; Region: MutL_C; pfam08676 216591016342 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and, score 7.9e-09 216591016343 PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 216591016344 HMMPfam hit to PF01119, DNA mismatch repair protein, C-termina, score 9.6e-32 216591016345 Predicted helix-turn-helix motif with score 1067.000, SD 2.82 at aa 633-654, sequence MEATERADQCNHGRPTWYQLTL 216591016346 tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091 216591016347 tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324 216591016348 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016349 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016350 HMMPfam hit to PF01715, IPP transferase, score 1.9e-116 216591016351 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591016352 Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909 216591016353 HMMPfam hit to PF02909, Tetracyclin repressor, C-terminal all-alpha, score 4.8e-38 216591016354 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591016355 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.7e-18 216591016356 PS01081 Bacterial regulatory proteins, tetR family signature. 216591016357 Predicted helix-turn-helix motif with score 1965.000, SD 5.88 at aa 18-39, sequence LSTRKLAERLGVQSPTLYWHFR 216591016358 CDS contains a frameshift mutation after codon 313. Similar to Escherichia coli tetracycline resistance protein, class C TetA SWALL:TCR3_ECOLI (SWALL:P02981) (396 aa) fasta scores: E(): 1e-72, 55.55% id in 387 aa 216591016359 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.2e-49 216591016360 Ketosteroid isomerase homolog [Function unknown]; Region: COG4319 216591016361 phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385 216591016362 PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196 216591016363 dimerization interface [polypeptide binding]; other site 216591016364 putative ATP binding site [chemical binding]; other site 216591016365 HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 1.5e-49 216591016366 HMMPfam hit to PF00586, AIR synthase related protein, N-terminal dom, score 3.8e-70 216591016367 DnaA regulatory inactivator Hda; Validated; Region: PRK08903 216591016368 ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593 216591016369 HMMPfam hit to PF00308, Bacterial dnaA protein, score 3.7e-05 216591016370 Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560 216591016371 haloacid dehalogenase-like hydrolase; Region: HAD; cl17202 216591016372 poly(A) polymerase; Region: pcnB; TIGR01942 216591016373 Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398 216591016374 active site 216591016375 NTP binding site [chemical binding]; other site 216591016376 metal binding triad [ion binding]; metal-binding site 216591016377 Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627 216591016378 Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626 216591016379 HMMPfam hit to PF01743, Poly A polymerase family, score 3.5e-54 216591016380 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483 216591016381 catalytic center binding site [active] 216591016382 ATP binding site [chemical binding]; other site 216591016383 HMMPfam hit to PF01288, 7,8-dihydro-6-hydroxymethylpterin-pyrophosph, score 3e-45 216591016384 PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 216591016385 Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428 216591016386 Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673 216591016387 Substrate-binding site [chemical binding]; other site 216591016388 Substrate specificity [chemical binding]; other site 216591016389 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016390 HMMPfam hit to PF01712, Deoxynucleoside kinase, score 1.7e-11 216591016391 Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557 216591016392 oligomerization interface [polypeptide binding]; other site 216591016393 active site 216591016394 metal binding site [ion binding]; metal-binding site 216591016395 HMMPfam hit to PF02548, Ketopantoate hydroxymethyltransferase, score 1.6e-135 216591016396 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016397 chorismate binding enzyme; Region: Chorismate_bind; cl10555 216591016398 Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147 216591016399 PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224 216591016400 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115 216591016401 homodimer interface [polypeptide binding]; other site 216591016402 substrate-cofactor binding pocket; other site 216591016403 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591016404 catalytic residue [active] 216591016405 HMMPfam hit to PF00425, chorismate binding enzyme, score 1.3e-75 216591016406 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016407 chaperone protein DnaJ; Provisional; Region: PRK10767 216591016408 DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257 216591016409 HSP70 interaction site [polypeptide binding]; other site 216591016410 Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719 216591016411 Zn binding sites [ion binding]; other site 216591016412 C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747 216591016413 dimer interface [polypeptide binding]; other site 216591016414 HMMPfam hit to PF01556, DnaJ C terminal region, score 4.6e-77 216591016415 HMMPfam hit to PF00684, DnaJ central domain (4 repeats), score 5.8e-44 216591016416 PS00190 Cytochrome c family heme-binding site signature. 216591016417 PS00637 CXXCXGXG dnaJ domain signature. 216591016418 PS00190 Cytochrome c family heme-binding site signature. 216591016419 HMMPfam hit to PF00226, DnaJ domain, score 1.4e-37 216591016420 PS00636 Nt-dnaJ domain signature. 216591016421 molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290 216591016422 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 216591016423 nucleotide binding site [chemical binding]; other site 216591016424 HMMPfam hit to PF00012, Hsp70 protein, score 0 216591016425 PS01036 Heat shock hsp70 proteins family signature 3. 216591016426 PS00329 Heat shock hsp70 proteins family signature 2. 216591016427 PS00297 Heat shock hsp70 proteins family signature 1. 216591016428 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 216591016429 catalytic residues [active] 216591016430 GrpE; Region: GrpE; pfam01025 216591016431 GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446 216591016432 dimer interface [polypeptide binding]; other site 216591016433 hsp70 (ATPase domain) interactions [polypeptide binding]; other site 216591016434 HMMPfam hit to PF01025, GrpE, score 3.5e-56 216591016435 PS01071 grpE protein signature. 216591016436 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 216591016437 RNA binding surface [nucleotide binding]; other site 216591016438 HMMPfam hit to PF01479, S4 domain, score 6.8e-11 216591016439 ferrochelatase; Reviewed; Region: hemH; PRK00035 216591016440 Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411 216591016441 C-terminal domain interface [polypeptide binding]; other site 216591016442 active site 216591016443 Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419 216591016444 active site 216591016445 N-terminal domain interface [polypeptide binding]; other site 216591016446 HMMPfam hit to PF00762, Ferrochelatase, score 1.1e-116 216591016447 PS00534 Ferrochelatase signature. 216591016448 heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082 216591016449 Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444 216591016450 HMMPfam hit to PF01628, HrcA protein C terminal domain, score 8.6e-54 216591016451 NAD(+)/NADH kinase family protein; Provisional; Region: ppnK; PRK02155 216591016452 inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231 216591016453 HMMPfam hit to PF01513, ATP-NAD kinase, score 5e-58 216591016454 ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497 216591016455 ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241 216591016456 Walker A/P-loop; other site 216591016457 ATP binding site [chemical binding]; other site 216591016458 Q-loop/lid; other site 216591016459 ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241 216591016460 ABC transporter signature motif; other site 216591016461 Walker B; other site 216591016462 D-loop; other site 216591016463 H-loop/switch region; other site 216591016464 HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 7.9e-10 216591016465 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016466 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072 216591016467 Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401 216591016468 metal binding triad; other site 216591016469 GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335 216591016470 Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401 216591016471 metal binding triad; other site 216591016472 GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335 216591016473 HMMPfam hit to PF03710, Glutamate-ammonia ligase adenylyltransferase, score 3.1e-79 216591016474 HMMPfam hit to PF03710, Glutamate-ammonia ligase adenylyltransferase, score 2.1e-72 216591016475 TIGR02099 family protein; Region: TIGR02099 216591016476 AsmA-like C-terminal region; Region: AsmA_2; pfam13502 216591016477 1 probable transmembrane helix predicted for BCAL3279 by TMHMM2.0 at aa 32-54 216591016478 nitrilase; Region: PLN02798 216591016479 Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572 216591016480 putative active site [active] 216591016481 catalytic triad [active] 216591016482 dimer interface [polypeptide binding]; other site 216591016483 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 1.8e-46 216591016484 protease TldD; Provisional; Region: tldD; PRK10735 216591016485 HMMPfam hit to PF01523, Putative modulator of DNA gyrase, score 2.4e-88 216591016486 phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261 216591016487 DAHP synthetase I family; Region: DAHP_synth_1; pfam00793 216591016488 HMMPfam hit to PF00793, DAHP synthetase I family, score 2.1e-161 216591016489 Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604 216591016490 PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872 216591016491 putative active site [active] 216591016492 HMMPfam hit to PF01850, PIN domain, score 6.5e-07 216591016493 bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289 216591016494 Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040 216591016495 heme-binding site [chemical binding]; other site 216591016496 FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184 216591016497 FAD binding pocket [chemical binding]; other site 216591016498 FAD binding motif [chemical binding]; other site 216591016499 phosphate binding motif [ion binding]; other site 216591016500 beta-alpha-beta structure motif; other site 216591016501 NAD binding pocket [chemical binding]; other site 216591016502 Heme binding pocket [chemical binding]; other site 216591016503 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 2.8e-15 216591016504 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 3.6e-05 216591016505 HMMPfam hit to PF00042, Globin, score 1.1e-18 216591016506 Cobalamin adenosyltransferase; Region: Cob_adeno_trans; cl00920 216591016507 HMMPfam hit to PF01923, Cobalamin adenosyltransferase, score 9.5e-86 216591016508 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 216591016509 FAD binding domain; Region: FAD_binding_4; pfam01565 216591016510 HMMPfam hit to PF01565, FAD binding domain, score 2.1e-54 216591016511 HMMPfam hit to PF02913, FAD linked oxidases, C-terminal domain, score 1.4e-75 216591016512 glycolate oxidase subunit GlcD; Provisional; Region: PRK11230 216591016513 FAD binding domain; Region: FAD_binding_4; pfam01565 216591016514 HMMPfam hit to PF01565, FAD binding domain, score 1.8e-54 216591016515 HMMPfam hit to PF02913, FAD linked oxidases, C-terminal domain, score 1.9e-75 216591016516 glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282 216591016517 FAD binding domain; Region: FAD_binding_4; pfam01565 216591016518 HMMPfam hit to PF01565, FAD binding domain, score 1.7e-22 216591016519 glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274 216591016520 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 216591016521 Cysteine-rich domain; Region: CCG; pfam02754 216591016522 Cysteine-rich domain; Region: CCG; pfam02754 216591016523 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0019 216591016524 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591016525 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0018 216591016526 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591016527 HMMPfam hit to PF02754, Cysteine-rich domain, score 1.2e-07 216591016528 HMMPfam hit to PF02754, Cysteine-rich domain, score 1.8e-09 216591016529 Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824 216591016530 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 216591016531 catalytic residue [active] 216591016532 HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 1.7e-32 216591016533 PS01211 Uncharacterized protein family UPF0001 signature. 216591016534 pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880 216591016535 pyrroline-5-carboxylate reductase; Region: PLN02688 216591016536 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 0.00053 216591016537 HMMPfam hit to PF03807, NADP oxidoreductase coenzyme F420-depe, score 3.6e-59 216591016538 PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 216591016539 Transposase; Region: HTH_Tnp_1; pfam01527 216591016540 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591016541 HMMPfam hit to PF01527, Transposase, score 1.2e-10 216591016542 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591016543 IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717 216591016544 HMMPfam hit to PF05717, IS66 Orf2 like protein, score 3.2e-62 216591016545 Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007 216591016546 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591016547 putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005 216591016548 Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050 216591016549 IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817 216591016550 HMMPfam hit to PF03050, Transposase IS66 family, score 1.1e-99 216591016551 4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848 216591016552 UbiA prenyltransferase family; Region: UbiA; pfam01040 216591016553 7 probable transmembrane helices predicted for BCAL3296 by TMHMM2.0 at aa 28-45, 101-123, 143-165, 169-188, 212-234, 244-261 and 273-295 216591016554 HMMPfam hit to PF01040, UbiA prenyltransferase family, score 5.1e-59 216591016555 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016556 PS00943 UbiA prenyltransferase family signature. 216591016557 DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783 216591016558 DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043 216591016559 dimerization interface [polypeptide binding]; other site 216591016560 DPS ferroxidase diiron center [ion binding]; other site 216591016561 ion pore; other site 216591016562 HMMPfam hit to PF00210, Ferritin-like domain, score 1.3e-33 216591016563 PS00819 Dps protein family signature 2. 216591016564 PS00818 Dps protein family signature 1. 216591016565 catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061 216591016566 N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649 216591016567 dimer interface [polypeptide binding]; other site 216591016568 active site 216591016569 heme binding site [chemical binding]; other site 216591016570 C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200 216591016571 HMMPfam hit to PF00141, Peroxidase, score 4.2e-120 216591016572 HMMPfam hit to PF00141, Peroxidase, score 5e-96 216591016573 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016574 PS00435 Peroxidases proximal heme-ligand signature. 216591016575 PS00436 Peroxidases active site signature. 216591016576 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591016577 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591016578 The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411 216591016579 dimerization interface [polypeptide binding]; other site 216591016580 HMMPfam hit to PF03466, LysR substrate binding domain, score 3e-49 216591016581 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.1e-16 216591016582 PS00044 Bacterial regulatory proteins, lysR family signature. 216591016583 Predicted helix-turn-helix motif with score 1707.000, SD 5.00 at aa 16-37, sequence RHFGRAAEACFVSQPTLSVAIK 216591016584 ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917 216591016585 RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488 216591016586 ssDNA binding site; other site 216591016587 generic binding surface II; other site 216591016588 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 216591016589 ATP binding site [chemical binding]; other site 216591016590 putative Mg++ binding site [ion binding]; other site 216591016591 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591016592 nucleotide binding region [chemical binding]; other site 216591016593 ATP-binding site [chemical binding]; other site 216591016594 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 4.7e-19 216591016595 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1.4e-33 216591016596 PS00435 Peroxidases proximal heme-ligand signature. 216591016597 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016598 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 0.00063 216591016599 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147 216591016600 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113 216591016601 HMMPfam hit to PF02547, Queuosine biosynthesis protein, score 5.7e-87 216591016602 queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112 216591016603 Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343 216591016604 HMMPfam hit to PF01702, Queuine tRNA-ribosyltransferase, score 2.8e-125 216591016605 preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585 216591016606 1 probable transmembrane helix predicted for BCAL3305 by TMHMM2.0 at aa 15-37 216591016607 HMMPfam hit to PF02699, Preprotein translocase subunit, score 1.3e-36 216591016608 SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721 216591016609 preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812 216591016610 SecD/SecF GG Motif; Region: Sec_GG; pfam07549 216591016611 protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916 216591016612 6 probable transmembrane helices predicted for BCAL3306 by TMHMM2.0 at aa 7-29, 447-469, 471-493, 497-519, 540-562 and 572-594 216591016613 HMMPfam hit to PF07549, SecD/SecF GG Motif, score 0.00082 216591016614 HMMPfam hit to PF02355, Protein export membrane protein, score 3.5e-07 216591016615 preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022 216591016616 SecD/SecF GG Motif; Region: Sec_GG; pfam07549 216591016617 Protein export membrane protein; Region: SecD_SecF; pfam02355 216591016618 6 probable transmembrane helices predicted for BCAL3307 by TMHMM2.0 at aa 17-39, 133-155, 160-182, 186-208, 248-266 and 270-292 216591016619 HMMPfam hit to PF07549, SecD/SecF GG Motif, score 1.4e-05 216591016620 HMMPfam hit to PF02355, Protein export membrane protein, score 7.9e-72 216591016621 PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988 216591016622 protein binding site [polypeptide binding]; other site 216591016623 C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526 216591016624 Active site serine [active] 216591016625 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 0.001 216591016626 HMMPfam hit to PF03572, Peptidase family S41, score 1.3e-41 216591016627 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 216591016628 citrate-proton symporter; Provisional; Region: PRK15075 216591016629 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591016630 putative substrate translocation pore; other site 216591016631 HMMPfam hit to PF00083, Sugar (and other) transporter, score 6.7e-08 216591016632 10 probable transmembrane helices predicted for BCAL3309 by TMHMM2.0 at aa 19-41, 61-83, 90-112, 190-209, 240-259, 274-296, 303-324, 334-356, 369-391 and 401-418 216591016633 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.8e-19 216591016634 PS00216 Sugar transport proteins signature 1. 216591016635 Uncharacterized conserved protein [Function unknown]; Region: COG2353 216591016636 HMMPfam hit to PF04264, YceI like family, score 2e-41 216591016637 YceI-like domain; Region: YceI; smart00867 216591016638 HMMPfam hit to PF04264, YceI like family, score 1.8e-32 216591016639 Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038 216591016640 HMMPfam hit to PF01292, Cytochrome b561 family, score 1.4e-49 216591016641 4 probable transmembrane helices predicted for BCAL3312 by TMHMM2.0 at aa 15-37, 57-74, 94-116 and 149-166 216591016642 Paraquat-inducible protein A; Region: PqiA; pfam04403 216591016643 HMMPfam hit to PF04403, Paraquat-inducible protein A, score 4.9e-45 216591016644 4 probable transmembrane helices predicted for BCAL3313 by TMHMM2.0 at aa 47-66, 96-118, 139-161 and 166-188 216591016645 Paraquat-inducible protein A; Region: PqiA; pfam04403 216591016646 HMMPfam hit to PF04403, Paraquat-inducible protein A, score 8.3e-80 216591016647 4 probable transmembrane helices predicted for BCAL3314 by TMHMM2.0 at aa 47-66, 95-117, 141-160 and 164-186 216591016648 Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008 216591016649 mce related protein; Region: MCE; pfam02470 216591016650 mce related protein; Region: MCE; pfam02470 216591016651 2 probable transmembrane helices predicted for BCAL3315 by TMHMM2.0 at aa 24-46 and 122-141 216591016652 HMMPfam hit to PF02470, mce related protein, score 2.7e-25 216591016653 HMMPfam hit to PF02470, mce related protein, score 0.00061 216591016654 HMMPfam hit to PF02470, mce related protein, score 3.8e-15 216591016655 Protein of unknown function (DUF330); Region: DUF330; pfam03886 216591016656 1 probable transmembrane helix predicted for BCAL3316 by TMHMM2.0 at aa 7-29 216591016657 HMMPfam hit to PF03886, Protein of unknown function (DUF330), score 1.6e-06 216591016658 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016659 Site-specific recombinase; Region: SpecificRecomb; pfam10136 216591016660 6 probable transmembrane helices predicted for BCAL3317 by TMHMM2.0 at aa 375-397, 407-429, 471-493, 513-535, 579-601 and 633-655 216591016661 Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116 216591016662 THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715 216591016663 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 216591016664 HMMPfam hit to PF02926, THUMP domain, score 8e-11 216591016665 HMMPfam hit to PF01170, Putative RNA methylase family UPF0020, score 3.6e-49 216591016666 PS00092 N-6 Adenine-specific DNA methylases signature. 216591016667 Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; some contain an N-terminal GntR family winged HTH DNA-binding domain; Region: SRPBCC_CalC_Aha1-like_GntR-HTH; cd08893 216591016668 putative hydrophobic ligand binding site [chemical binding]; other site 216591016669 HMMPfam hit to PF08327, Activator of Hsp90 ATPase homolog 1-like pro, score 4.3e-11 216591016670 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591016671 dimerization interface [polypeptide binding]; other site 216591016672 putative DNA binding site [nucleotide binding]; other site 216591016673 putative Zn2+ binding site [ion binding]; other site 216591016674 HMMPfam hit to PF08279, HTH domain, score 0.00074 216591016675 HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family, score 8.6e-07 216591016676 Predicted helix-turn-helix motif with score 1428.000, SD 4.05 at aa 26-47, sequence QTLSELCDGLAMSRQAVSKHLA 216591016677 N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247 216591016678 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591016679 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 0.0048 216591016680 Predicted transcriptional regulator [Transcription]; Region: COG2378 216591016681 HTH domain; Region: HTH_11; pfam08279 216591016682 WYL domain; Region: WYL; pfam13280 216591016683 HMMPfam hit to PF08279, HTH domain, score 8.7e-18 216591016684 Predicted helix-turn-helix motif with score 1959.000, SD 5.86 at aa 21-42, sequence TTAQQLADWLSVSPRTVYRDVR 216591016685 Nitrilases, cyanide hydratase (CH)s, and similar proteins (class 1 nitrilases); Region: nitrilases_CHs; cd07564 216591016686 Predicted amidohydrolase [General function prediction only]; Region: COG0388 216591016687 putative active site [active] 216591016688 catalytic triad [active] 216591016689 putative dimer interface [polypeptide binding]; other site 216591016690 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 7.2e-50 216591016691 PS00921 Nitrilases / cyanide hydratase active site signature. 216591016692 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591016693 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591016694 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_2; cd08464 216591016695 putative substrate binding pocket [chemical binding]; other site 216591016696 putative dimerization interface [polypeptide binding]; other site 216591016697 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.5e-19 216591016698 Predicted helix-turn-helix motif with score 1163.000, SD 3.15 at aa 24-45, sequence GGASRAALRLDLTQSAVSAALG 216591016699 PS00044 Bacterial regulatory proteins, lysR family signature. 216591016700 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.5e-13 216591016701 NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282 216591016702 NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233 216591016703 HMMPfam hit to PF02233, NAD(P) transhydrogenase beta subunit, score 5.3e-260 216591016704 8 probable transmembrane helices predicted for BCAL3325 by TMHMM2.0 at aa 4-21, 34-53, 63-85, 97-116, 143-165, 185-204, 209-231 and 252-274 216591016705 Domain of unknown function (DUF3814); Region: DUF3814; pfam12769 216591016706 3 probable transmembrane helices predicted for BCAL3326 by TMHMM2.0 at aa 4-26, 39-61 and 65-84 216591016707 Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304 216591016708 NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288 216591016709 ligand binding site [chemical binding]; other site 216591016710 homodimer interface [polypeptide binding]; other site 216591016711 NAD(P) binding site [chemical binding]; other site 216591016712 trimer interface B [polypeptide binding]; other site 216591016713 trimer interface A [polypeptide binding]; other site 216591016714 HMMPfam hit to PF01262, Alanine dehydrogenase/PNT, C-terminal dom, score 2.3e-79 216591016715 HMMPfam hit to PF05222, Alanine dehydrogenase/PNT, N-terminal dom, score 1.3e-48 216591016716 Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675 216591016717 nudix motif; other site 216591016718 HMMPfam hit to PF00293, NUDIX domain, score 1.3e-14 216591016719 PS00893 mutT domain signature. 216591016720 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482 216591016721 tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998 216591016722 HMMPfam hit to PF03054, tRNA methyl transferase, score 1.6e-192 216591016723 PS00070 Aldehyde dehydrogenases cysteine active site. 216591016724 Glutamate synthase domain 2 [Amino acid transport and metabolism]; Region: GltB; COG0069 216591016725 Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808 216591016726 active site 216591016727 FMN binding site [chemical binding]; other site 216591016728 substrate binding site [chemical binding]; other site 216591016729 3Fe-4S cluster binding site [ion binding]; other site 216591016730 1 probable transmembrane helix predicted for BCAL3330 by TMHMM2.0 at aa 21-43 216591016731 HMMPfam hit to PF01645, Conserved region in glutamate synthase, score 2.2e-81 216591016732 PS00881 Protein splicing signature. 216591016733 putative glutathione S-transferase; Provisional; Region: PRK10357 216591016734 GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049 216591016735 putative C-terminal domain interface [polypeptide binding]; other site 216591016736 putative GSH binding site (G-site) [chemical binding]; other site 216591016737 putative dimer interface [polypeptide binding]; other site 216591016738 C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205 216591016739 dimer interface [polypeptide binding]; other site 216591016740 N-terminal domain interface [polypeptide binding]; other site 216591016741 putative substrate binding pocket (H-site) [chemical binding]; other site 216591016742 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 8.7e-05 216591016743 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 7.9e-08 216591016744 Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195 216591016745 proline aminopeptidase P II; Provisional; Region: PRK10879 216591016746 Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087 216591016747 active site 216591016748 HMMPfam hit to PF05195, Aminopeptidase P, N-terminal domain, score 2.3e-39 216591016749 HMMPfam hit to PF00557, metallopeptidase family M24, score 4.4e-80 216591016750 PS00491 Aminopeptidase P and proline dipeptidase signature. 216591016751 hypothetical protein; Provisional; Region: PRK06996 216591016752 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591016753 HMMPfam hit to PF01494, FAD binding domain, score 7.9e-08 216591016754 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00051 216591016755 PS01304 ubiH/COQ6 monooxygenase family signature. 216591016756 tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415 216591016757 Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801 216591016758 FMN binding site [chemical binding]; other site 216591016759 active site 216591016760 catalytic residues [active] 216591016761 substrate binding site [chemical binding]; other site 216591016762 HMMPfam hit to PF01207, Dihydrouridine synthase (Dus), score 1.8e-127 216591016763 PS01136 Uncharacterized protein family UPF0034 signature. 216591016764 Predicted helix-turn-helix motif with score 976.000, SD 2.51 at aa 158-179, sequence ITVARLAEAAGISMLTVHGRTR 216591016765 DNA-binding protein Fis; Provisional; Region: PRK01905 216591016766 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis family, score 1.5e-12 216591016767 Predicted helix-turn-helix motif with score 1686.000, SD 4.93 at aa 51-72, sequence GNQSLAAEYLGINRNTLRKKLQ 216591016768 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881 216591016769 Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal ATIC formylase domain that formylates...; Region: IMPCH; cd01421 216591016770 purine monophosphate binding site [chemical binding]; other site 216591016771 dimer interface [polypeptide binding]; other site 216591016772 putative catalytic residues [active] 216591016773 AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798 216591016774 AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362 216591016775 HMMPfam hit to PF02142, MGS-like domain, score 2.5e-68 216591016776 HMMPfam hit to PF01808, AICARFT/IMPCHase bienzyme, score 1.8e-164 216591016777 PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 216591016778 Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529 216591016779 active site 216591016780 putative DNA-binding cleft [nucleotide binding]; other site 216591016781 dimer interface [polypeptide binding]; other site 216591016782 HMMPfam hit to PF02075, Crossover junction endodeoxyribonuclease Ruv, score 6.3e-68 216591016783 Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116 216591016784 RuvA N terminal domain; Region: RuvA_N; pfam01330 216591016785 RuvA, C-terminal domain; Region: RuvA_C; pfam07499 216591016786 HMMPfam hit to PF01330, RuvA N terminal domain, score 1.3e-31 216591016787 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591016788 HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 0.0063 216591016789 HMMPfam hit to PF07499, RuvA, C-terminal domain, score 5.5e-11 216591016790 Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080 216591016791 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591016792 Walker A motif; other site 216591016793 ATP binding site [chemical binding]; other site 216591016794 Walker B motif; other site 216591016795 arginine finger; other site 216591016796 Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491 216591016797 HMMPfam hit to PF05496, Holliday junction DNA helicase ruvB N-termin, score 1.1e-28 216591016798 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.1e-31 216591016799 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 1.4e-05 216591016800 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016801 HMMPfam hit to PF05491, Holliday junction DNA helicase ruvB C-termin, score 2.9e-53 216591016802 Uncharacterized protein conserved in bacteria (DUF2236); Region: DUF2236; cl01472 216591016803 Putative ParB-like nuclease; Region: ParBc_2; cl17538 216591016804 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016805 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 216591016806 catalytic core [active] 216591016807 HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 1.9e-55 216591016808 D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563 216591016809 putative active site [active] 216591016810 dimerization interface [polypeptide binding]; other site 216591016811 putative tRNAtyr binding site [nucleotide binding]; other site 216591016812 HMMPfam hit to PF02580, D-Tyr-tRNA(Tyr) deacylase, score 5.9e-62 216591016813 tyrosyl-tRNA synthetase; Validated; Region: PRK05912 216591016814 catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805 216591016815 active site 216591016816 HIGH motif; other site 216591016817 dimer interface [polypeptide binding]; other site 216591016818 KMSKS motif; other site 216591016819 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 216591016820 RNA binding surface [nucleotide binding]; other site 216591016821 HMMPfam hit to PF01479, S4 domain, score 9.7e-05 216591016822 HMMPfam hit to PF00579, tRNA synthetases class I (W and Y), score 3.5e-99 216591016823 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591016824 anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585 216591016825 HMMPfam hit to PF03702, Uncharacterised protein family (UPF0075), score 1.5e-152 216591016826 iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623 216591016827 PS01152 Hypothetical hesB/yadR/yfhF family signature. 216591016828 HMMPfam hit to PF01521, Iron-sulphur cluster biosynthesis, score 5.5e-39 216591016829 30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132 216591016830 HMMPfam hit to PF00380, Ribosomal protein S9/S16, score 1.7e-58 216591016831 PS00360 Ribosomal protein S9 signature. 216591016832 Ribosomal protein L13. Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392 216591016833 23S rRNA interface [nucleotide binding]; other site 216591016834 L3 interface [polypeptide binding]; other site 216591016835 HMMPfam hit to PF00572, Ribosomal protein L13, score 1.2e-71 216591016836 OsmC-like protein; Region: OsmC; cl00767 216591016837 HMMPfam hit to PF02566, OsmC-like protein, score 5.5e-27 216591016838 Protein of unknown function (DUF3025); Region: DUF3025; pfam11227 216591016839 Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294 216591016840 active site 216591016841 substrate binding pocket [chemical binding]; other site 216591016842 dimer interface [polypeptide binding]; other site 216591016843 HMMPfam hit to PF01979, Amidohydrolase family, score 1.1e-63 216591016844 PS00483 Dihydroorotase signature 2. 216591016845 PS00482 Dihydroorotase signature 1. 216591016846 Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121 216591016847 Glutamine amidotransferases class-II (Gn-AT)_YafJ-type. YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea. YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908 216591016848 putative dimer interface [polypeptide binding]; other site 216591016849 putative active site [active] 216591016850 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 2.3e-12 216591016851 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 216591016852 Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344 216591016853 outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414 216591016854 Autotransporter beta-domain; Region: Autotransporter; smart00869 216591016855 HMMPfam hit to PF03212, Pertactin, score 9.9e-07 216591016856 HMMPfam hit to PF03797, Autotransporter beta-domain, score 4.7e-24 216591016857 CDS contains a frameshift after codon 152. Similar to Escherichia coli glutamate/aspartate transport ATP-binding protein GltL UniProt:P0AAG3 (EMBL:EC10981) (241 aa) fasta scores: E()=3e-63, 82.988% id in 241 aa 216591016858 HMMPfam hit to PF00005, ABC transporter, score 3.3e-61 216591016859 PS00211 ABC transporters family signature. 216591016860 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016861 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591016862 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591016863 dimer interface [polypeptide binding]; other site 216591016864 conserved gate region; other site 216591016865 putative PBP binding loops; other site 216591016866 ABC-ATPase subunit interface; other site 216591016867 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.7e-31 216591016868 5 probable transmembrane helices predicted for BCAL3356 by TMHMM2.0 at aa 26-48, 61-83, 93-115, 155-177 and 197-219 216591016869 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591016870 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591016871 dimer interface [polypeptide binding]; other site 216591016872 conserved gate region; other site 216591016873 putative PBP binding loops; other site 216591016874 ABC-ATPase subunit interface; other site 216591016875 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.1e-34 216591016876 4 probable transmembrane helices predicted for BCAL3357 by TMHMM2.0 at aa 32-54, 67-89, 104-126 and 211-233 216591016877 glutamate and aspartate transporter subunit; Provisional; Region: PRK10797 216591016878 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591016879 substrate binding pocket [chemical binding]; other site 216591016880 membrane-bound complex binding site; other site 216591016881 hinge residues; other site 216591016882 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 9.3e-56 216591016883 Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334 216591016884 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812 216591016885 NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076 216591016886 NAD(P) binding site [chemical binding]; other site 216591016887 HMMPfam hit to PF00208, Glutamate/Leucine/Phenylalanine/Valin, score 9.6e-122 216591016888 HMMPfam hit to PF02812, Glu/Leu/Phe/Val dehydrogenase, dimeri, score 1e-67 216591016889 PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 216591016890 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591016891 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591016892 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591016893 dimerization interface [polypeptide binding]; other site 216591016894 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.1e-15 216591016895 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.7e-16 216591016896 PS00044 Bacterial regulatory proteins, lysR family signature. 216591016897 Predicted helix-turn-helix motif with score 1273.000, SD 3.52 at aa 16-37, sequence RSFSRSAELRHVSQPAFSRRIQ 216591016898 adenylosuccinate lyase; Provisional; Region: PRK09285 216591016899 PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598 216591016900 tetramer interface [polypeptide binding]; other site 216591016901 active site 216591016902 HMMPfam hit to PF00206, Lyase, score 1.1e-66 216591016903 PS00163 Fumarate lyases signature. 216591016904 HMMPfam hit to PF08328, Adenylosuccinate lyase C-terminal, score 2.3e-91 216591016905 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591016906 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591016907 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.5e-62 216591016908 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591016909 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591016910 Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909 216591016911 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.1e-10 216591016912 Predicted helix-turn-helix motif with score 1043.000, SD 2.74 at aa 50-71, sequence FSVRKLAQSVGCDPMSVLYHFK 216591016913 HMMPfam hit to PF02909, Tetracyclin repressor, C-terminal all-alpha, score 0.00011 216591016914 Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021 216591016915 ATP-binding site [chemical binding]; other site 216591016916 Gluconate-6-phosphate binding site [chemical binding]; other site 216591016917 Shikimate kinase; Region: SKI; pfam01202 216591016918 HMMPfam hit to PF01202, Shikimate kinase, score 7.8e-14 216591016919 PS00017 ATP/GTP-binding site motif A (P-loop). 216591016920 fructuronate transporter; Provisional; Region: PRK10034; cl15264 216591016921 GntP family permease; Region: GntP_permease; pfam02447 216591016922 12 probable transmembrane helices predicted for BCAL3365 by TMHMM2.0 at aa 7-25, 29-48, 60-79, 107-129, 142-161, 181-203, 232-254, 269-291, 304-326, 364-386, 393-415 and 430-452 216591016923 HMMPfam hit to PF02447, GntP family permease, score 3e-218 216591016924 HMMPfam hit to PF03600, Citrate transporter, score 1.7e-05 216591016925 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016926 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718 216591016927 KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452 216591016928 active site 216591016929 intersubunit interface [polypeptide binding]; other site 216591016930 catalytic residue [active] 216591016931 HMMPfam hit to PF01081, KDPG and KHG aldolase, score 3e-74 216591016932 PS00160 KDPG and KHG aldolases Schiff-base forming residue. 216591016933 PS00159 KDPG and KHG aldolases active site. 216591016934 phosphogluconate dehydratase; Validated; Region: PRK09054 216591016935 6-phosphogluconate dehydratase; Region: edd; TIGR01196 216591016936 HMMPfam hit to PF00920, Dehydratase family, score 1.2e-264 216591016937 PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 216591016938 PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 216591016939 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 216591016940 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 216591016941 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 216591016942 putative active site [active] 216591016943 HMMPfam hit to PF01418, Helix-turn-helix domain, rpiR family, score 2.7e-30 216591016944 Predicted helix-turn-helix motif with score 1373.000, SD 3.86 at aa 33-54, sequence LAMTELSTRAGVSQPTIARFCQ 216591016945 HMMPfam hit to PF01380, SIS domain, score 4.2e-25 216591016946 Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863 216591016947 HMMPfam hit to PF03653, Uncharacterised protein family (UPF0093), score 1.1e-32 216591016948 4 probable transmembrane helices predicted for BCAL3369 by TMHMM2.0 at aa 10-32, 53-75, 80-102 and 115-137 216591016949 Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079 216591016950 gamma-glutamyl phosphate reductase; Region: proA; TIGR00407 216591016951 putative catalytic cysteine [active] 216591016952 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 4.9e-09 216591016953 PS01223 Gamma-glutamyl phosphate reductase signature. 216591016954 DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574 216591016955 DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144 216591016956 HMMPfam hit to PF06144, DNA polymerase III, delta subunit, score 2.7e-41 216591016957 Lipopolysaccharide-assembly; Region: LptE; cl01125 216591016958 HMMPfam hit to PF04390, Rare lipoprotein B family, score 8.9e-08 216591016959 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016960 leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390 216591016961 catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812 216591016962 HIGH motif; other site 216591016963 Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603 216591016964 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 216591016965 active site 216591016966 KMSKS motif; other site 216591016967 Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958 216591016968 tRNA binding surface [nucleotide binding]; other site 216591016969 Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020 216591016970 HMMPfam hit to PF08264, Anticodon-binding domain, score 1.8e-11 216591016971 HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 6.3e-13 216591016972 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591016973 TolR protein; Region: tolR; TIGR02801 216591016974 Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848 216591016975 HMMPfam hit to PF02472, Biopolymer transport protein ExbD/TolR, score 3.3e-17 216591016976 1 probable transmembrane helix predicted for BCAL3374 by TMHMM2.0 at aa 20-42 216591016977 MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568 216591016978 HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 2.5e-42 216591016979 3 probable transmembrane helices predicted for BCAL3375 by TMHMM2.0 at aa 15-37, 128-150 and 174-196 216591016980 dihydrodipicolinate reductase; Provisional; Region: PRK00048 216591016981 Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113 216591016982 Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173 216591016983 HMMPfam hit to PF05173, Dihydrodipicolinate reductase, C-termin, score 2.4e-78 216591016984 PS01298 Dihydrodipicolinate reductase signature. 216591016985 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ross, score 0.00064 216591016986 HMMPfam hit to PF03447, Homoserine dehydrogenase, NAD binding d, score 0.0038 216591016987 Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913 216591016988 SmpA / OmlA family; Region: SmpA_OmlA; pfam04355 216591016989 HMMPfam hit to PF04355, SmpA / OmlA family, score 6.2e-41 216591016990 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591016991 ferric uptake regulator; Provisional; Region: fur; PRK09462 216591016992 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 216591016993 metal binding site 2 [ion binding]; metal-binding site 216591016994 putative DNA binding helix; other site 216591016995 metal binding site 1 [ion binding]; metal-binding site 216591016996 dimer interface [polypeptide binding]; other site 216591016997 structural Zn2+ binding site [ion binding]; other site 216591016998 HMMPfam hit to PF01475, Ferric uptake regulator family, score 1.7e-66 216591016999 ureidoglycolate hydrolase; Provisional; Region: PRK13395 216591017000 Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194 216591017001 HMMPfam hit to PF04115, Ureidoglycolate hydrolase, score 6.4e-107 216591017002 allantoicase; Provisional; Region: PRK13257 216591017003 Allantoicase repeat; Region: Allantoicase; pfam03561 216591017004 Allantoicase repeat; Region: Allantoicase; pfam03561 216591017005 HMMPfam hit to PF03561, Allantoicase repeat, score 2e-67 216591017006 HMMPfam hit to PF03561, Allantoicase repeat, score 1.6e-77 216591017007 C4-dicarboxylate transporter DctA; Reviewed; Region: PRK13027 216591017008 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 216591017009 8 probable transmembrane helices predicted for BCAL3381 by TMHMM2.0 at aa 7-29, 44-63, 76-98, 150-167, 184-206, 219-241, 351-373 and 379-401 216591017010 HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 1.2e-135 216591017011 PS00713 Sodium:dicarboxylate symporter family signature 1. 216591017012 Transcriptional regulators [Transcription]; Region: FadR; COG2186 216591017013 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591017014 DNA-binding site [nucleotide binding]; DNA binding site 216591017015 FCD domain; Region: FCD; pfam07729 216591017016 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 3.3e-18 216591017017 PS00043 Bacterial regulatory proteins, gntR family signature. 216591017018 HMMPfam hit to PF07729, FCD domain, score 1.7e-19 216591017019 DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242 216591017020 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591017021 The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425 216591017022 dimerization interface [polypeptide binding]; other site 216591017023 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.5e-54 216591017024 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.6e-26 216591017025 PS00044 Bacterial regulatory proteins, lysR family signature. 216591017026 Predicted helix-turn-helix motif with score 2158.000, SD 6.54 at aa 28-49, sequence RSFTRAADALHVSQPTLSQQVR 216591017027 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591017028 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591017029 putative substrate translocation pore; other site 216591017030 12 probable transmembrane helices predicted for BCAL3384 by TMHMM2.0 at aa 19-41, 51-73, 80-99, 104-126, 138-160, 164-186, 215-237, 252-274, 279-301, 311-333, 340-362 and 367-389 216591017031 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.3e-32 216591017032 L-idonate 5-dehydrogenase; Provisional; Region: PRK09880 216591017033 L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232 216591017034 putative NAD(P) binding site [chemical binding]; other site 216591017035 catalytic Zn binding site [ion binding]; other site 216591017036 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 4.9e-33 216591017037 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 7.7e-47 216591017038 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591017039 gluconate 5-dehydrogenase; Provisional; Region: PRK07523 216591017040 gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347 216591017041 NADP binding site [chemical binding]; other site 216591017042 homodimer interface [polypeptide binding]; other site 216591017043 active site 216591017044 HMMPfam hit to PF00106, short chain dehydrogenase, score 1e-35 216591017045 PS00061 Short-chain dehydrogenases/reductases family signature. 216591017046 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 216591017047 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591017048 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 216591017049 dimerization interface [polypeptide binding]; other site 216591017050 substrate binding pocket [chemical binding]; other site 216591017051 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.3e-20 216591017052 Predicted helix-turn-helix motif with score 1051.000, SD 2.77 at aa 16-37, sequence LHFGRAAQRLFIVQPALSMQIK 216591017053 PS00044 Bacterial regulatory proteins, lysR family signature. 216591017054 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.1e-44 216591017055 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057 216591017056 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846 216591017057 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800 216591017058 HMMPfam hit to PF02800, Glyceraldehyde 3-phosphate dehydrogenase, C-, score 1.6e-97 216591017059 PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 216591017060 HMMPfam hit to PF00044, Glyceraldehyde 3-phosphate dehydrogenase, NA, score 7.7e-99 216591017061 transketolase; Reviewed; Region: PRK12753 216591017062 Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012 216591017063 TPP-binding site [chemical binding]; other site 216591017064 dimer interface [polypeptide binding]; other site 216591017065 Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033 216591017066 PYR/PP interface [polypeptide binding]; other site 216591017067 dimer interface [polypeptide binding]; other site 216591017068 TPP binding site [chemical binding]; other site 216591017069 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 216591017070 HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 1.8e-11 216591017071 HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 3.2e-59 216591017072 HMMPfam hit to PF00456, Transketolase, thiamine diphosphate b, score 1.2e-231 216591017073 PS00801 Transketolase signature 1. 216591017074 spermidine synthase; Provisional; Region: PRK00811 216591017075 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591017076 HMMPfam hit to PF01564, Spermine/spermidine synthase, score 1.3e-51 216591017077 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_8; cd07246 216591017078 putative dimer interface [polypeptide binding]; other site 216591017079 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591017080 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 2.7e-20 216591017081 PS00192 Cytochrome b/b6 heme-ligand signature. 216591017082 16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713 216591017083 HMMPfam hit to PF04452, Protein of unknown function (DUF558), score 3.1e-89 216591017084 Barstar_evA4336-like contains uncharacterized sequences similar to the uncharacterized, predicted RNAase inhibitor evA4336 found in Azoarcus sp. EvN1. This is a subfamily of the Barstar family of RNAase inhibitors. Barstar is an intracellular inhibitor...; Region: Barstar_evA4336-like; cd05141 216591017085 putative RNAase interaction site [polypeptide binding]; other site 216591017086 RNase_Sa. Ribonucleases first isolated from Streptomyces aureofaciens. In general, ribonucleases cleave phosphodiester bonds in RNA and are essential for both non-specific RNA degradation and for numerous forms of RNA processing. RNAse Sa is a guanylate...; Region: RNase_Sa; cd00607 216591017087 active site 216591017088 barstar interaction site; other site 216591017089 HMMPfam hit to PF00545, ribonuclease, score 4.7e-15 216591017090 1 probable transmembrane helix predicted for BCAL3394 by TMHMM2.0 at aa 13-35 216591017091 malic enzyme; Reviewed; Region: PRK12862 216591017092 Malic enzyme, N-terminal domain; Region: malic; pfam00390 216591017093 NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311 216591017094 putative NAD(P) binding site [chemical binding]; other site 216591017095 Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280 216591017096 HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 1.5e-119 216591017097 HMMPfam hit to PF03949, Malic enzyme, NAD binding domain, score 2.6e-124 216591017098 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017099 HMMPfam hit to PF00390, Malic enzyme, N-terminal domain, score 9e-70 216591017100 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017101 thiamine monophosphate kinase; Provisional; Region: PRK05731 216591017102 ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194 216591017103 ATP binding site [chemical binding]; other site 216591017104 dimerization interface [polypeptide binding]; other site 216591017105 HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 0.00042 216591017106 Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971 216591017107 tetramer interfaces [polypeptide binding]; other site 216591017108 binuclear metal-binding site [ion binding]; other site 216591017109 HMMPfam hit to PF04608, Phosphatidylglycerophosphatase A, score 8.3e-46 216591017110 4 probable transmembrane helices predicted for BCAL3397 by TMHMM2.0 at aa 39-61, 74-91, 111-133 and 154-176 216591017111 Competence-damaged protein; Region: CinA; pfam02464 216591017112 HMMPfam hit to PF02464, Competence-damaged protein, score 8.3e-77 216591017113 Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725 216591017114 active site 216591017115 dimer interface [polypeptide binding]; other site 216591017116 HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase / HUMP, score 1e-35 216591017117 PS00156 Orotidine 5'-phosphate decarboxylase active site. 216591017118 aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021 216591017119 active site 216591017120 catalytic residues [active] 216591017121 HMMPfam hit to PF01263, Aldose 1-epimerase, score 7.8e-30 216591017122 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557 216591017123 classical (c) SDRs; Region: SDR_c; cd05233 216591017124 NAD(P) binding site [chemical binding]; other site 216591017125 active site 216591017126 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.2e-20 216591017127 PS00061 Short-chain dehydrogenases/reductases family signature. 216591017128 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591017129 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591017130 TM-ABC transporter signature motif; other site 216591017131 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 7e-67 216591017132 8 probable transmembrane helices predicted for BCAL3403 by TMHMM2.0 at aa 36-53, 63-85, 90-109, 113-135, 142-161, 181-203, 233-255 and 287-309 216591017133 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017134 L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288 216591017135 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 216591017136 Walker A/P-loop; other site 216591017137 ATP binding site [chemical binding]; other site 216591017138 Q-loop/lid; other site 216591017139 ABC transporter signature motif; other site 216591017140 Walker B; other site 216591017141 D-loop; other site 216591017142 H-loop/switch region; other site 216591017143 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 216591017144 HMMPfam hit to PF00005, ABC transporter, score 1.4e-10 216591017145 PS00211 ABC transporters family signature. 216591017146 HMMPfam hit to PF00005, ABC transporter, score 5.2e-54 216591017147 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017148 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879 216591017149 Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540 216591017150 ligand binding site [chemical binding]; other site 216591017151 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 1.2e-48 216591017152 short chain dehydrogenase; Provisional; Region: PRK07063 216591017153 classical (c) SDRs; Region: SDR_c; cd05233 216591017154 NAD(P) binding site [chemical binding]; other site 216591017155 active site 216591017156 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.3e-31 216591017157 PS00061 Short-chain dehydrogenases/reductases family signature. 216591017158 2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140 216591017159 KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452 216591017160 active site 216591017161 intersubunit interface [polypeptide binding]; other site 216591017162 catalytic residue [active] 216591017163 HMMPfam hit to PF01081, KDPG and KHG aldolase, score 2.5e-11 216591017164 2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734 216591017165 2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035 216591017166 HMMPfam hit to PF05035, 2-keto-3-deoxy-galactonokinase, score 3.9e-53 216591017167 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591017168 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 216591017169 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591017170 Predicted helix-turn-helix motif with score 1050.000, SD 2.76 at aa 277-298, sequence REARAISAELGWSPPQGTRRIK 216591017171 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 3.2e-15 216591017172 Predicted helix-turn-helix motif with score 1050.000, SD 2.76 at aa 60-81, sequence RDMRAIGAALGTTRSTTHRLVS 216591017173 EF-hand domain pair; Region: EF_hand_5; pfam13499 216591017174 1 probable transmembrane helix predicted for BCAL3410 by TMHMM2.0 at aa 5-27 216591017175 Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939 216591017176 Serine carboxypeptidase; Region: Peptidase_S10; cl08270 216591017177 HMMPfam hit to PF00450, Serine carboxypeptidase, score 5.2e-06 216591017178 monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056 216591017179 Transglycosylase; Region: Transgly; cl17702 216591017180 HMMPfam hit to PF00912, Transglycosylase, score 3.2e-65 216591017181 1 probable transmembrane helix predicted for BCAL3412 by TMHMM2.0 at aa 13-35 216591017182 shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258 216591017183 Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501 216591017184 NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065 216591017185 shikimate binding site; other site 216591017186 NAD(P) binding site [chemical binding]; other site 216591017187 HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase, score 1.7e-15 216591017188 HMMPfam hit to PF08501, Shikimate dehydrogenase substrate bind, score 2.1e-33 216591017189 Exoribonuclease R [Transcription]; Region: VacB; COG0557 216591017190 RNB domain; Region: RNB; pfam00773 216591017191 HMMPfam hit to PF00773, RNB-like protein, score 5.1e-15 216591017192 Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886 216591017193 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591017194 HMMPfam hit to PF05728, Uncharacterised protein family (UPF0227), score 3.3e-75 216591017195 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081 216591017196 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 216591017197 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 216591017198 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 216591017199 HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 8.7e-06 216591017200 HMMPfam hit to PF08245, Mur ligase middle domain, score 4.7e-20 216591017201 HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 1.6e-27 216591017202 TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966 216591017203 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591017204 catalytic residues [active] 216591017205 1 probable transmembrane helix predicted for BCAL3418 by TMHMM2.0 at aa 7-29 216591017206 HMMPfam hit to PF08534, Redoxin, score 1e-31 216591017207 PS00194 Thioredoxin family active site. 216591017208 Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466 216591017209 Dehydroquinase class II; Region: DHquinase_II; pfam01220 216591017210 active site 216591017211 trimer interface [polypeptide binding]; other site 216591017212 dimer interface [polypeptide binding]; other site 216591017213 HMMPfam hit to PF01220, Dehydroquinase class II, score 1.8e-87 216591017214 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302 216591017215 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 216591017216 carboxyltransferase (CT) interaction site; other site 216591017217 biotinylation site [posttranslational modification]; other site 216591017218 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 4.5e-37 216591017219 PS00188 Biotin-requiring enzymes attachment site. 216591017220 acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591 216591017221 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 216591017222 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 216591017223 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 216591017224 HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 4.3e-52 216591017225 HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase,, score 0.00023 216591017226 HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 1.6e-113 216591017227 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 216591017228 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 216591017229 HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain, score 5.4e-63 216591017230 Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325 216591017231 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 216591017232 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591017233 S-adenosylmethionine binding site [chemical binding]; other site 216591017234 HMMPfam hit to PF06325, Ribosomal protein L11 methyltransfera, score 9.3e-139 216591017235 HMMPfam hit to PF05175, Methyltransferase small domain, score 5.4e-05 216591017236 HMMPfam hit to PF08241, Methyltransferase domain, score 5e-09 216591017237 HMMPfam hit to PF08242, Methyltransferase domain, score 2.5e-08 216591017238 MJ0042 family finger-like domain; Region: MJ0042_CXXC; TIGR02098 216591017239 Protein of unknown function (DUF3426); Region: DUF3426; pfam11906 216591017240 PS00190 Cytochrome c family heme-binding site signature. 216591017241 1 probable transmembrane helix predicted for BCAL3423 by TMHMM2.0 at aa 310-332 216591017242 Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014 216591017243 dimer interface [polypeptide binding]; other site 216591017244 catalytic triad [active] 216591017245 peroxidatic and resolving cysteines [active] 216591017246 HMMPfam hit to PF08534, Redoxin, score 2.8e-45 216591017247 PS01265 Tpx family signature. 216591017248 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 216591017249 Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time; Region: ribokinase_group_A; cd01942 216591017250 substrate binding site [chemical binding]; other site 216591017251 ATP binding site [chemical binding]; other site 216591017252 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 6.1e-33 216591017253 Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470 216591017254 1 probable transmembrane helix predicted for BCAL3426 by TMHMM2.0 at aa 7-29 216591017255 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017256 HMMPfam hit to PF05433, Rickettsia 17 kDa surface antigen, score 4.3e-07 216591017257 Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049 216591017258 dimer interface [polypeptide binding]; other site 216591017259 putative radical transfer pathway; other site 216591017260 diiron center [ion binding]; other site 216591017261 tyrosyl radical; other site 216591017262 HMMPfam hit to PF00268, Ribonucleotide reductase, small chain, score 5.1e-30 216591017263 1 probable transmembrane helix predicted for BCAL3428 by TMHMM2.0 at aa 240-262 216591017264 ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07207 216591017265 ATP cone domain; Region: ATP-cone; pfam03477 216591017266 Class I ribonucleotide reductase; Region: RNR_I; cd01679 216591017267 active site 216591017268 dimer interface [polypeptide binding]; other site 216591017269 catalytic residues [active] 216591017270 effector binding site; other site 216591017271 R2 peptide binding site; other site 216591017272 HMMPfam hit to PF02867, Ribonucleotide reductase, barrel doma, score 9.6e-177 216591017273 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017274 PS00089 Ribonucleotide reductase large subunit signature. 216591017275 HMMPfam hit to PF00317, Ribonucleotide reductase, all-alpha d, score 4.3e-27 216591017276 HMMPfam hit to PF03477, ATP cone domain, score 9.2e-23 216591017277 N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023 216591017278 Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583 216591017279 amidase catalytic site [active] 216591017280 Zn binding residues [ion binding]; other site 216591017281 substrate binding site [chemical binding]; other site 216591017282 HMMPfam hit to PF01510, N-acetylmuramoyl-L-alanine amidase, score 1.5e-55 216591017283 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591017284 Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504 216591017285 HMMPfam hit to PF01578, Cytochrome C assembly protein, score 9.6e-18 216591017286 8 probable transmembrane helices predicted for BCAL3432 by TMHMM2.0 at aa 4-21, 50-72, 76-98, 110-132, 142-164, 202-224, 239-256 and 269-288 216591017287 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591017288 signal recognition particle protein; Provisional; Region: PRK10867 216591017289 SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963 216591017290 The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115 216591017291 P loop; other site 216591017292 GTP binding site [chemical binding]; other site 216591017293 Signal peptide binding domain; Region: SRP_SPB; pfam02978 216591017294 HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain, score 2.2e-28 216591017295 HMMPfam hit to PF00448, SRP54-type protein, GTPase domain, score 1.9e-108 216591017296 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017297 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591017298 HMMPfam hit to PF02978, Signal peptide binding domain, score 2.8e-40 216591017299 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 216591017300 active site 216591017301 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 7.2e-15 216591017302 1 probable transmembrane helix predicted for BCAL3434 by TMHMM2.0 at aa 46-68 216591017303 PS00215 Mitochondrial energy transfer proteins signature. 216591017304 MarC family integral membrane protein; Region: MarC; cl00919 216591017305 6 probable transmembrane helices predicted for BCAL3435 by TMHMM2.0 at aa 5-27, 40-59, 71-93, 108-130, 137-156 and 176-198 216591017306 HMMPfam hit to PF01914, MarC family integral membrane protein, score 4e-50 216591017307 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591017308 prolyl-tRNA synthetase; Provisional; Region: PRK09194 216591017309 Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779 216591017310 dimer interface [polypeptide binding]; other site 216591017311 motif 1; other site 216591017312 active site 216591017313 motif 2; other site 216591017314 INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334 216591017315 putative deacylase active site [active] 216591017316 Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268 216591017317 active site 216591017318 motif 3; other site 216591017319 ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861 216591017320 anticodon binding site; other site 216591017321 HMMPfam hit to PF03129, Anticodon binding domain, score 6.3e-23 216591017322 HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associa, score 5.2e-13 216591017323 HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 9.2e-62 216591017324 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591017325 Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671 216591017326 putative active site [active] 216591017327 Ap4A binding site [chemical binding]; other site 216591017328 nudix motif; other site 216591017329 putative metal binding site [ion binding]; other site 216591017330 HMMPfam hit to PF00293, NUDIX domain, score 3.3e-21 216591017331 PS00893 mutT domain signature. 216591017332 CNP1-like family; Region: CNP1; pfam08750 216591017333 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017334 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591017335 gamma-glutamyl kinase; Provisional; Region: PRK05429 216591017336 AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242 216591017337 nucleotide binding site [chemical binding]; other site 216591017338 homotetrameric interface [polypeptide binding]; other site 216591017339 putative phosphate binding site [ion binding]; other site 216591017340 putative allosteric binding site; other site 216591017341 PUA domain; Region: PUA; pfam01472 216591017342 HMMPfam hit to PF01472, PUA domain, score 1.3e-25 216591017343 HMMPfam hit to PF00696, Amino acid kinase family, score 1.1e-59 216591017344 PS00902 Glutamate 5-kinase signature. 216591017345 GTPase CgtA; Reviewed; Region: obgE; PRK12299 216591017346 GTP1/OBG; Region: GTP1_OBG; pfam01018 216591017347 Obg GTPase; Region: Obg; cd01898 216591017348 G1 box; other site 216591017349 GTP/Mg2+ binding site [chemical binding]; other site 216591017350 Switch I region; other site 216591017351 G2 box; other site 216591017352 G3 box; other site 216591017353 Switch II region; other site 216591017354 G4 box; other site 216591017355 G5 box; other site 216591017356 HMMPfam hit to PF01926, GTPase of unknown function, score 3.5e-38 216591017357 PS00905 GTP1/OBG family signature. 216591017358 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017359 HMMPfam hit to PF01018, GTP1/OBG, score 1.2e-76 216591017360 50S ribosomal protein L27; Validated; Region: rpmA; PRK05435 216591017361 HMMPfam hit to PF01016, Ribosomal L27 protein, score 2.5e-50 216591017362 PS00831 Ribosomal protein L27 signature. 216591017363 50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278 216591017364 50S ribosomal protein L21; Validated; Region: rplU; PRK05573 216591017365 HMMPfam hit to PF00829, Ribosomal prokaryotic L21 protein, score 6.7e-57 216591017366 PS01169 Ribosomal protein L21 signature. 216591017367 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142 216591017368 Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685 216591017369 substrate binding pocket [chemical binding]; other site 216591017370 chain length determination region; other site 216591017371 substrate-Mg2+ binding site; other site 216591017372 catalytic residues [active] 216591017373 aspartate-rich region 1; other site 216591017374 active site lid residues [active] 216591017375 aspartate-rich region 2; other site 216591017376 HMMPfam hit to PF00348, Polyprenyl synthetase, score 1.4e-84 216591017377 PS00723 Polyprenyl synthetases signature 1. 216591017378 Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism]; Region: CorB; COG4536 216591017379 Domain of unknown function DUF21; Region: DUF21; pfam01595 216591017380 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 216591017381 Transporter associated domain; Region: CorC_HlyC; smart01091 216591017382 4 probable transmembrane helices predicted for BCAL3444 by TMHMM2.0 at aa 4-26, 61-83, 93-115 and 144-161 216591017383 HMMPfam hit to PF01595, Domain of unknown function DUF21, score 4.8e-50 216591017384 HMMPfam hit to PF00571, CBS domain pair, score 7.5e-24 216591017385 HMMPfam hit to PF03471, Transporter associated domain, score 6.2e-11 216591017386 Type II/IV secretion system protein; Region: T2SE; pfam00437 216591017387 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 216591017388 Walker A motif; other site 216591017389 ATP binding site [chemical binding]; other site 216591017390 Walker B motif; other site 216591017391 HMMPfam hit to PF00437, Type II/IV secretion system protein, score 8.9e-110 216591017392 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017393 PS00662 Bacterial type II secretion system protein E signature. 216591017394 PS00190 Cytochrome c family heme-binding site signature. 216591017395 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 216591017396 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 216591017397 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 3.8e-17 216591017398 PS00874 Bacterial type II secretion system protein F signature. 216591017399 3 probable transmembrane helices predicted for BCAL3446 by TMHMM2.0 at aa 167-189, 209-231 and 373-395 216591017400 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 9.4e-20 216591017401 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989 216591017402 Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750 216591017403 Type IV leader peptidase family; Region: Peptidase_A24; pfam01478 216591017404 6 probable transmembrane helices predicted for BCAL3447 by TMHMM2.0 at aa 25-47, 142-164, 179-201, 208-230, 245-267 and 279-301 216591017405 HMMPfam hit to PF06750, Bacterial Peptidase A24 N-terminal doma, score 7.2e-47 216591017406 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591017407 HMMPfam hit to PF01478, Type IV leader peptidase family, score 8.9e-26 216591017408 Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237 216591017409 Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022 216591017410 CoA-binding site [chemical binding]; other site 216591017411 ATP-binding [chemical binding]; other site 216591017412 HMMPfam hit to PF01121, Dephospho-CoA kinase, score 3.2e-76 216591017413 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017414 hypothetical protein; Provisional; Region: PRK05287 216591017415 HMMPfam hit to PF07072, Protein of unknown function (DUF1342), score 3.5e-118 216591017416 The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425 216591017417 active site 216591017418 8-oxo-dGMP binding site [chemical binding]; other site 216591017419 nudix motif; other site 216591017420 metal binding site [ion binding]; metal-binding site 216591017421 HMMPfam hit to PF00293, NUDIX domain, score 9.2e-21 216591017422 PS00893 mutT domain signature. 216591017423 Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG2607 216591017424 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591017425 Walker A motif; other site 216591017426 ATP binding site [chemical binding]; other site 216591017427 Walker B motif; other site 216591017428 HMMPfam hit to PF05673, Protein of unknown function (DUF815), score 6e-67 216591017429 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017430 Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152 216591017431 heterotetramer interface [polypeptide binding]; other site 216591017432 active site pocket [active] 216591017433 cleavage site 216591017434 HMMPfam hit to PF01960, ArgJ family, score 1.1e-180 216591017435 preprotein translocase subunit SecA; Reviewed; Region: PRK12904 216591017436 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251 216591017437 SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958 216591017438 SEC-C motif; Region: SEC-C; pfam02810 216591017439 HMMPfam hit to PF02810, SEC-C motif, score 1e-10 216591017440 HMMPfam hit to PF07516, SecA Wing and Scaffold domain, score 1.8e-97 216591017441 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.011 216591017442 PS01312 Protein secA signatures. 216591017443 HMMPfam hit to PF07517, SecA DEAD-like domain, score 1.7e-218 216591017444 HMMPfam hit to PF01043, SecA preprotein cross-linking domain, score 2.1e-77 216591017445 Protein of unknown function (DUF721); Region: DUF721; pfam05258 216591017446 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186 216591017447 UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331 216591017448 HMMPfam hit to PF03331, UDP-3-O-acyl N-acetylglycosamine deacetylase, score 1.5e-150 216591017449 Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; Region: PRX5_like; cd03013 216591017450 catalytic triad [active] 216591017451 dimer interface [polypeptide binding]; other site 216591017452 HMMPfam hit to PF08534, Redoxin, score 4.3e-63 216591017453 HMMPfam hit to PF00578, AhpC/TSA family, score 0.0024 216591017454 cell division protein FtsZ; Validated; Region: PRK09330 216591017455 FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes. FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201 216591017456 nucleotide binding site [chemical binding]; other site 216591017457 SulA interaction site; other site 216591017458 HMMPfam hit to PF03953, Tubulin/FtsZ family, C-terminal domain, score 2.4e-27 216591017459 HMMPfam hit to PF00091, Tubulin/FtsZ family, GTPase domain, score 1.6e-83 216591017460 PS01135 FtsZ protein signature 2. 216591017461 cell division protein FtsA; Region: ftsA; TIGR01174 216591017462 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 216591017463 nucleotide binding site [chemical binding]; other site 216591017464 Cell division protein FtsA; Region: FtsA; pfam14450 216591017465 HMMPfam hit to PF02491, Cell division protein FtsA, score 8.7e-76 216591017466 PS01036 Heat shock hsp70 proteins family signature 3. 216591017467 HMMPfam hit to PF02491, Cell division protein FtsA, score 6.1e-88 216591017468 Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589 216591017469 POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478 216591017470 Cell division protein FtsQ; Region: FtsQ; pfam03799 216591017471 HMMPfam hit to PF03799, Cell division protein FtsQ, score 0.00097 216591017472 HMMPfam hit to PF08478, POTRA domain, FtsQ-type, score 8.5e-24 216591017473 1 probable transmembrane helix predicted for BCAL3459 by TMHMM2.0 at aa 10-32 216591017474 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017475 D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372 216591017476 D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820 216591017477 ATP-grasp domain; Region: ATP-grasp_4; cl17255 216591017478 HMMPfam hit to PF07478, D-ala D-ala ligase C-terminus, score 4.3e-79 216591017479 HMMPfam hit to PF02222, ATP-grasp domain, score 0.0019 216591017480 HMMPfam hit to PF01820, D-ala D-ala ligase N-terminus, score 2.5e-22 216591017481 UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421 216591017482 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 216591017483 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 216591017484 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 216591017485 HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 1.8e-23 216591017486 HMMPfam hit to PF08245, Mur ligase middle domain, score 2.4e-36 216591017487 HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 4.4e-44 216591017488 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726 216591017489 MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785 216591017490 active site 216591017491 homodimer interface [polypeptide binding]; other site 216591017492 HMMPfam hit to PF04101, Glycosyltransferase family, score 1.1e-39 216591017493 HMMPfam hit to PF03033, Glycosyltransferase family, score 9.1e-36 216591017494 cell division protein FtsW; Region: ftsW; TIGR02614 216591017495 HMMPfam hit to PF01098, Cell cycle protein, score 2e-124 216591017496 10 probable transmembrane helices predicted for BCAL3463 by TMHMM2.0 at aa 57-79, 94-113, 126-143, 158-180, 192-209, 213-232, 237-254, 315-337, 357-375 and 390-412 216591017497 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02006 216591017498 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 216591017499 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 216591017500 HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 3.5e-09 216591017501 HMMPfam hit to PF08245, Mur ligase middle domain, score 2.2e-57 216591017502 phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108 216591017503 Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852 216591017504 Mg++ binding site [ion binding]; other site 216591017505 putative catalytic motif [active] 216591017506 putative substrate binding site [chemical binding]; other site 216591017507 10 probable transmembrane helices predicted for BCAL3465 by TMHMM2.0 at aa 22-44, 65-87, 97-114, 134-153, 194-216, 223-242, 257-279, 286-308, 312-334 and 367-386 216591017508 HMMPfam hit to PF00953, Glycosyl transferase family, score 3.6e-55 216591017509 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591017510 UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770 216591017511 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 216591017512 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 216591017513 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 216591017514 HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 7.6e-12 216591017515 HMMPfam hit to PF08245, Mur ligase middle domain, score 1.3e-44 216591017516 HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 2.8e-17 216591017517 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139 216591017518 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 216591017519 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 216591017520 HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 2.7e-33 216591017521 HMMPfam hit to PF08245, Mur ligase middle domain, score 4.4e-64 216591017522 HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 0.0018 216591017523 Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768 216591017524 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 216591017525 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 216591017526 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 6.6e-94 216591017527 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017528 HMMPfam hit to PF03717, Penicillin-binding Protein dimerisatio, score 2.9e-48 216591017529 1 probable transmembrane helix predicted for BCAL3468 by TMHMM2.0 at aa 29-48 216591017530 Cell division protein FtsL; Region: FtsL; cl11433 216591017531 MraW methylase family; Region: Methyltransf_5; cl17771 216591017532 16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050 216591017533 HMMPfam hit to PF01795, MraW methylase family, score 4.7e-134 216591017534 cell division protein MraZ; Reviewed; Region: PRK00326 216591017535 MraZ protein; Region: MraZ; pfam02381 216591017536 MraZ protein; Region: MraZ; pfam02381 216591017537 HMMPfam hit to PF02381, MraZ protein, score 2.3e-14 216591017538 HMMPfam hit to PF02381, MraZ protein, score 6.7e-11 216591017539 Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042 216591017540 diiron binding motif [ion binding]; other site 216591017541 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591017542 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591017543 trimer interface [polypeptide binding]; other site 216591017544 eyelet of channel; other site 216591017545 HMMPfam hit to PF00267, Gram-negative porin, score 1.9e-06 216591017546 Long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07059 216591017547 Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936 216591017548 acyl-activating enzyme (AAE) consensus motif; other site 216591017549 putative AMP binding site [chemical binding]; other site 216591017550 putative active site [active] 216591017551 putative CoA binding site [chemical binding]; other site 216591017552 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.5e-129 216591017553 PS00455 Putative AMP-binding domain signature. 216591017554 The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766 216591017555 Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243 216591017556 putative [4Fe-4S] binding site [ion binding]; other site 216591017557 putative molybdopterin cofactor binding site [chemical binding]; other site 216591017558 The MopB_CT_3 CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. This CD is of the...; Region: MopB_CT_3; cd02786 216591017559 putative molybdopterin cofactor binding site; other site 216591017560 HMMPfam hit to PF01568, Molydopterin dinucleotide binding dom, score 1.9e-25 216591017561 HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 1.4e-54 216591017562 HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 do, score 8.3e-13 216591017563 Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038 216591017564 HMMPfam hit to PF01292, Cytochrome b561 family, score 1.1e-34 216591017565 4 probable transmembrane helices predicted for BCAL3476 by TMHMM2.0 at aa 13-32, 42-64, 90-112 and 142-164 216591017566 Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153 216591017567 putative heme binding pocket [chemical binding]; other site 216591017568 HMMPfam hit to PF00199, Catalase, score 6e-11 216591017569 1 probable transmembrane helix predicted for BCAL3477 by TMHMM2.0 at aa 20-42 216591017570 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591017571 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591017572 DNA binding residues [nucleotide binding] 216591017573 HMMPfam hit to PF04542, Sigma-70 region, score 7.6e-12 216591017574 HMMPfam hit to PF08281, Sigma-70, region, score 2.4e-15 216591017575 HMMPfam hit to PF04545, Sigma-70, region, score 1.3e-13 216591017576 Predicted helix-turn-helix motif with score 1168.000, SD 3.17 at aa 128-149, sequence FTYQEAADLLEVPIGTVMSRLS 216591017577 Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662 216591017578 1 probable transmembrane helix predicted for BCAL3479 by TMHMM2.0 at aa 83-105 216591017579 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 216591017580 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 216591017581 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 216591017582 Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586 216591017583 HMMPfam hit to PF01609, Transposase DDE domain, score 3.6e-32 216591017584 Protein of unknown function (DUF2628); Region: DUF2628; pfam10947 216591017585 3 probable transmembrane helices predicted for BCAL3485 by TMHMM2.0 at aa 64-86, 90-109 and 142-164 216591017586 RNA polymerase sigma factor SigJ; Provisional; Region: PRK09636 216591017587 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591017588 HMMPfam hit to PF08281, Sigma-70, region, score 6.4e-11 216591017589 HMMPfam hit to PF04542, Sigma-70 region, score 1.9e-13 216591017590 Uncharacterized conserved protein [Function unknown]; Region: COG2128 216591017591 Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627 216591017592 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 8.1e-22 216591017593 ergothioneine biosynthesis protein EgtB; Region: egtB_TIGR03440 216591017594 Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781 216591017595 HMMPfam hit to PF03781, Domain of unknown function (DUF323), score 1.8e-19 216591017596 dimethylhistidine N-methyltransferase; Region: egtD_ergothio; TIGR03438 216591017597 Uncharacterized conserved protein (DUF2260); Region: DUF2260; pfam10017 216591017598 2 probable transmembrane helices predicted for BCAL3490 by TMHMM2.0 at aa 5-22 and 37-59 216591017599 2 probable transmembrane helices predicted for BCAL3491 by TMHMM2.0 at aa 7-29 and 34-56 216591017600 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017601 1 probable transmembrane helix predicted for BCAL3492 by TMHMM2.0 at aa 7-26 216591017602 Restriction endonuclease [Defense mechanisms]; Region: COG3587 216591017603 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 216591017604 ATP binding site [chemical binding]; other site 216591017605 putative Mg++ binding site [ion binding]; other site 216591017606 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 3.2e-06 216591017607 Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189 216591017608 DNA methylase; Region: N6_N4_Mtase; pfam01555 216591017609 DNA methylase; Region: N6_N4_Mtase; cl17433 216591017610 HMMPfam hit to PF01555, DNA methylase, score 1.4e-28 216591017611 PS00092 N-6 Adenine-specific DNA methylases signature. 216591017612 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591017613 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591017614 trimer interface [polypeptide binding]; other site 216591017615 eyelet of channel; other site 216591017616 HMMPfam hit to PF00267, Gram-negative porin, score 0.0042 216591017617 PS00099 Thiolases active site. 216591017618 transcriptional regulatory protein TctD; Provisional; Region: PRK15479 216591017619 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591017620 active site 216591017621 phosphorylation site [posttranslational modification] 216591017622 intermolecular recognition site; other site 216591017623 dimerization interface [polypeptide binding]; other site 216591017624 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591017625 DNA binding site [nucleotide binding] 216591017626 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 3.7e-18 216591017627 HMMPfam hit to PF00072, Response regulator receiver domain, score 5e-38 216591017628 Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521 216591017629 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591017630 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591017631 dimer interface [polypeptide binding]; other site 216591017632 phosphorylation site [posttranslational modification] 216591017633 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591017634 ATP binding site [chemical binding]; other site 216591017635 Mg2+ binding site [ion binding]; other site 216591017636 G-X-G motif; other site 216591017637 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.3e-37 216591017638 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.3e-11 216591017639 2 probable transmembrane helices predicted for BCAL3497 by TMHMM2.0 at aa 10-29 and 163-182 216591017640 HMMPfam hit to PF08521, Two-component sensor kinase N-terminal, score 1.3e-45 216591017641 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591017642 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591017643 dimer interface [polypeptide binding]; other site 216591017644 conserved gate region; other site 216591017645 putative PBP binding loops; other site 216591017646 ABC-ATPase subunit interface; other site 216591017647 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.4e-23 216591017648 6 probable transmembrane helices predicted for BCAL3498 by TMHMM2.0 at aa 34-53, 98-117, 124-146, 150-172, 204-226 and 249-271 216591017649 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 216591017650 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 216591017651 Walker A/P-loop; other site 216591017652 ATP binding site [chemical binding]; other site 216591017653 Q-loop/lid; other site 216591017654 ABC transporter signature motif; other site 216591017655 Walker B; other site 216591017656 D-loop; other site 216591017657 H-loop/switch region; other site 216591017658 HMMPfam hit to PF00005, ABC transporter, score 3.4e-58 216591017659 PS00211 ABC transporters family signature. 216591017660 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017661 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432 216591017662 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 216591017663 membrane-bound complex binding site; other site 216591017664 hinge residues; other site 216591017665 PS00217 Sugar transport proteins signature 2. 216591017666 flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701 216591017667 HMMPfam hit to PF01311, Bacterial export proteins, family, score 1.7e-61 216591017668 6 probable transmembrane helices predicted for BCAL3501 by TMHMM2.0 at aa 15-37, 44-61, 71-93, 129-151, 183-205 and 212-234 216591017669 flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700 216591017670 HMMPfam hit to PF01313, Bacterial export proteins, family, score 1.1e-36 216591017671 2 probable transmembrane helices predicted for BCAL3502 by TMHMM2.0 at aa 15-37 and 49-71 216591017672 flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699 216591017673 HMMPfam hit to PF00813, FliP family, score 2.9e-113 216591017674 5 probable transmembrane helices predicted for BCAL3503 by TMHMM2.0 at aa 13-35, 55-77, 97-114, 191-213 and 226-245 216591017675 PS01061 Flagella transport protein fliP family signature 2. 216591017676 PS01060 Flagella transport protein fliP family signature 1. 216591017677 Flagellar biosynthesis protein, FliO; Region: FliO; pfam04347 216591017678 HMMPfam hit to PF04347, Flagellar biosynthesis protein, FliO, score 4.6e-12 216591017679 2 probable transmembrane helices predicted for BCAL3504 by TMHMM2.0 at aa 13-32 and 61-83 216591017680 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017681 Surface presentation of antigens (SPOA); Region: SpoA; cl00819 216591017682 HMMPfam hit to PF01052, Surface presentation of antigens (SPOA) prot, score 2.6e-30 216591017683 flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666 216591017684 Surface presentation of antigens (SPOA); Region: SpoA; pfam01052 216591017685 HMMPfam hit to PF01052, Surface presentation of antigens (SPOA) prot, score 0.025 216591017686 HMMPfam hit to PF02154, Flagellar motor switch protein FliM, score 6e-98 216591017687 flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021 216591017688 HMMPfam hit to PF03748, Flagellar basal body-associated protein FliL, score 2.3e-31 216591017689 1 probable transmembrane helix predicted for BCAL3507 by TMHMM2.0 at aa 21-43 216591017690 Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346 216591017691 HMMPfam hit to PF04172, LrgB-like family, score 2.9e-96 216591017692 5 probable transmembrane helices predicted for BCAL3508 by TMHMM2.0 at aa 13-32, 47-69, 101-123, 160-182 and 215-237 216591017693 LrgA family; Region: LrgA; pfam03788 216591017694 HMMPfam hit to PF03788, LrgA family, score 3e-29 216591017695 4 probable transmembrane helices predicted for BCAL3509 by TMHMM2.0 at aa 20-42, 52-70, 83-105 and 110-132 216591017696 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591017697 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591017698 The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438 216591017699 putative dimerization interface [polypeptide binding]; other site 216591017700 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.3e-22 216591017701 Predicted helix-turn-helix motif with score 1827.000, SD 5.41 at aa 16-37, sequence QSFTAAADKLFVTQPTISKMVK 216591017702 PS00044 Bacterial regulatory proteins, lysR family signature. 216591017703 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.6e-46 216591017704 Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118 216591017705 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591017706 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591017707 putative substrate translocation pore; other site 216591017708 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591017709 13 probable transmembrane helices predicted for BCAL3511 by TMHMM2.0 at aa 21-43, 63-85, 92-111, 116-138, 151-173, 178-200, 212-234, 239-261, 281-303, 318-335, 347-369, 379-401 and 490-507 216591017710 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.1e-61 216591017711 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017712 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591017713 MarR family; Region: MarR_2; cl17246 216591017714 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017715 HMMPfam hit to PF01047, MarR family, score 2.2e-16 216591017716 1 probable transmembrane helix predicted for BCAL3513 by TMHMM2.0 at aa 32-54 216591017717 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591017718 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017719 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.3e-39 216591017720 HMMPfam hit to PF02321, Outer membrane efflux protein, score 6.8e-53 216591017721 Type II secretion system (T2SS), protein N; Region: T2SN; pfam01203 216591017722 1 probable transmembrane helix predicted for BCAL3515 by TMHMM2.0 at aa 20-42 216591017723 Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612 216591017724 HMMPfam hit to PF04612, General secretion pathway, M protein, score 9.8e-60 216591017725 1 probable transmembrane helix predicted for BCAL3516 by TMHMM2.0 at aa 24-46 216591017726 CDS contains a frameshift, and possible internal deletion, after codon 220. Similar to Vibrio cholerae general secretion pathway protein L EpsL UniProt:P45782 (EMBL:AE004338) (407 aa) fasta scores: E()=0.045, 25.310% id in 403 aa, and to Burkholderia cenocepacia AU 1054 general secretion pathway protein L UniProt:Q456C2 (EMBL:AAHI01000010) (457 aa) fasta scores: E()=1.5e-72, 90.372% id in 457 aa 216591017727 HMMPfam hit to PF05134, General secretion pathway protein L (GspL), score 5.8e-65 216591017728 Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934 216591017729 HMMPfam hit to PF03934, General secretion pathway protein K, score 7.4e-33 216591017730 PS00041 Bacterial regulatory proteins, araC family signature. 216591017731 1 probable transmembrane helix predicted for BCAL3519 by TMHMM2.0 at aa 16-38 216591017732 HMMPfam hit to PF07963, Prokaryotic N-terminal methylation motif, score 5.8e-09 216591017733 1 probable transmembrane helix predicted for BCAL3520 by TMHMM2.0 at aa 13-35 216591017734 PS00409 Prokaryotic N-terminal methylation site. 216591017735 type II secretion system protein I; Region: gspI; TIGR01707 216591017736 Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501 216591017737 HMMPfam hit to PF02501, Bacterial type II secretion system protein I, score 1.5e-32 216591017738 1 probable transmembrane helix predicted for BCAL3521 by TMHMM2.0 at aa 15-37 216591017739 HMMPfam hit to PF07963, Prokaryotic N-terminal methylation motif, score 1.7e-06 216591017740 Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830 216591017741 type II secretion system protein H; Region: typeII_sec_gspH; TIGR01708 216591017742 Type II transport protein GspH; Region: GspH; pfam12019 216591017743 1 probable transmembrane helix predicted for BCAL3522 by TMHMM2.0 at aa 13-35 216591017744 HMMPfam hit to PF07963, Prokaryotic N-terminal methylation motif, score 4.4e-06 216591017745 PS00409 Prokaryotic N-terminal methylation site. 216591017746 prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532 216591017747 type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710 216591017748 Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334 216591017749 HMMPfam hit to PF08334, Bacterial type II secretion system protein G, score 7.2e-67 216591017750 HMMPfam hit to PF07963, Prokaryotic N-terminal methylation motif, score 5.4e-09 216591017751 1 probable transmembrane helix predicted for BCAL3523 by TMHMM2.0 at aa 17-39 216591017752 PS00409 Prokaryotic N-terminal methylation site. 216591017753 Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356 216591017754 1 probable transmembrane helix predicted for BCAL3524 by TMHMM2.0 at aa 5-27 216591017755 type II secretion system protein F; Region: GspF; TIGR02120 216591017756 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 216591017757 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 216591017758 3 probable transmembrane helices predicted for BCAL3525 by TMHMM2.0 at aa 167-189, 220-239 and 376-398 216591017759 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 8.3e-17 216591017760 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 7.5e-25 216591017761 Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157 216591017762 type II secretion system protein E; Region: type_II_gspE; TIGR02533 216591017763 PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129 216591017764 Walker A motif; other site 216591017765 ATP binding site [chemical binding]; other site 216591017766 Walker B motif; other site 216591017767 HMMPfam hit to PF00437, Type II/IV secretion system protein, score 6.8e-136 216591017768 PS00662 Bacterial type II secretion system protein E signature. 216591017769 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017770 type II secretion system protein D; Region: type_II_gspD; TIGR02517 216591017771 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 216591017772 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 216591017773 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 216591017774 pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519 216591017775 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 216591017776 HMMPfam hit to PF00263, Bacterial type II and III secretion system, score 3.2e-88 216591017777 HMMPfam hit to PF03958, Bacterial type II/III secretion system sho, score 2.4e-13 216591017778 HMMPfam hit to PF03958, Bacterial type II/III secretion system sho, score 1.6e-08 216591017779 HMMPfam hit to PF03958, Bacterial type II/III secretion system sho, score 2.6e-11 216591017780 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 216591017781 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591017782 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591017783 catalytic residue [active] 216591017784 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 2.1e-28 216591017785 Putative GTPases (G3E family) [General function prediction only]; Region: COG0523 216591017786 CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492 216591017787 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833 216591017788 HMMPfam hit to PF02492, CobW/HypB/UreG, nucleotide-binding domain, score 4.8e-88 216591017789 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017790 HMMPfam hit to PF07683, Cobalamin synthesis protein cobW C-terminal, score 1.3e-37 216591017791 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 216591017792 IHF dimer interface [polypeptide binding]; other site 216591017793 IHF - DNA interface [nucleotide binding]; other site 216591017794 HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 1.1e-46 216591017795 PS00045 Bacterial histone-like DNA-binding proteins signature. 216591017796 bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747 216591017797 S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711 216591017798 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 216591017799 HMMPfam hit to PF05430, Protein of unknown function (DUF752), score 3.2e-31 216591017800 1 probable transmembrane helix predicted for BCAL3531 by TMHMM2.0 at aa 55-77 216591017801 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 6.1e-48 216591017802 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017803 RNA polymerase sigma factor; Provisional; Region: PRK12545 216591017804 Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281 216591017805 DNA binding residues [nucleotide binding] 216591017806 HMMPfam hit to PF04542, Sigma-70 region, score 1.7e-12 216591017807 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017808 HMMPfam hit to PF08281, Sigma-70, region, score 5.8e-05 216591017809 Putative zinc-finger; Region: zf-HC2; pfam13490 216591017810 Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034 216591017811 ArsC family; Region: ArsC; pfam03960 216591017812 catalytic residues [active] 216591017813 HMMPfam hit to PF03960, ArsC family, score 2.1e-34 216591017814 ParA-like protein; Provisional; Region: PHA02518 216591017815 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 216591017816 P-loop; other site 216591017817 Magnesium ion binding site [ion binding]; other site 216591017818 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 9.2e-18 216591017819 Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475 216591017820 ParB-like nuclease domain; Region: ParB; smart00470 216591017821 HMMPfam hit to PF02195, ParB-like nuclease domain, score 1.4e-11 216591017822 Predicted helix-turn-helix motif with score 1577.000, SD 4.56 at aa 204-225, sequence QSQKELSEHLGLDESTVAVALS 216591017823 Initiator Replication protein; Region: Rep_3; pfam01051 216591017824 Plasmid replication region DNA-binding N-term; Region: KfrA_N; pfam11740 216591017825 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236 216591017826 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 216591017827 active site 216591017828 catalytic residues [active] 216591017829 Int/Topo IB signature motif; other site 216591017830 DNA binding site [nucleotide binding] 216591017831 HMMPfam hit to PF00589, Phage integrase family, score 0.00032 216591017832 Protein of unknown function (DUF2471); Region: DUF2471; pfam10616 216591017833 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591017834 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591017835 non-specific DNA binding site [nucleotide binding]; other site 216591017836 salt bridge; other site 216591017837 sequence-specific DNA binding site [nucleotide binding]; other site 216591017838 Cupin domain; Region: Cupin_2; pfam07883 216591017839 HMMPfam hit to PF07883, Cupin domain, score 1.4e-11 216591017840 HMMPfam hit to PF01381, Helix-turn-helix, score 5.1e-17 216591017841 Predicted helix-turn-helix motif with score 1501.000, SD 4.30 at aa 39-60, sequence LTLDDLSRAAGVSKSMLSEIER 216591017842 pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825 216591017843 KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454 216591017844 substrate-cofactor binding pocket; other site 216591017845 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591017846 catalytic residue [active] 216591017847 HMMPfam hit to PF00202, Aminotransferase class-III, score 0.02 216591017848 HMMPfam hit to PF00155, Aminotransferase class I and II, score 2.4e-92 216591017849 HMMPfam hit to PF00464, Serine hydroxymethyltransferase, score 0.00023 216591017850 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 216591017851 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017852 L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396 216591017853 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 216591017854 NAD(P) binding site [chemical binding]; other site 216591017855 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 3.2e-43 216591017856 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591017857 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 9.4e-42 216591017858 2 probable transmembrane helices predicted for BCAM0012 by TMHMM2.0 at aa 24-46 and 56-78 216591017859 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 216591017860 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.2e-15 216591017861 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591017862 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591017863 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 8.3e-15 216591017864 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017865 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3558 216591017866 SnoaL-like domain; Region: SnoaL_2; pfam12680 216591017867 HMMPfam hit to PF07080, Protein of unknown function (DUF1348), score 2.8e-95 216591017868 tartrate dehydrogenase; Region: TTC; TIGR02089 216591017869 Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473 216591017870 HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase, score 7.2e-103 216591017871 PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 216591017872 transcriptional activator TtdR; Provisional; Region: PRK09801 216591017873 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591017874 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479 216591017875 putative effector binding pocket; other site 216591017876 putative dimerization interface [polypeptide binding]; other site 216591017877 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4e-18 216591017878 Predicted helix-turn-helix motif with score 1242.000, SD 3.42 at aa 20-41, sequence ASFSAAAEQLAVSPAYVSKRIA 216591017879 HMMPfam hit to PF03466, LysR substrate binding domain, score 5.9e-45 216591017880 N-acetyl-gamma-glutamyl-phosphate reductase; Provisional; Region: PRK11863 216591017881 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 216591017882 HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindin, score 9.8e-11 216591017883 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591017884 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591017885 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591017886 dimerization interface [polypeptide binding]; other site 216591017887 PS00228 Tubulin-beta mRNA autoregulation signal. 216591017888 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.7e-15 216591017889 Predicted helix-turn-helix motif with score 1158.000, SD 3.13 at aa 19-40, sequence GSFVAAAQWLHLAPPTVSLHVA 216591017890 PS00044 Bacterial regulatory proteins, lysR family signature. 216591017891 HMMPfam hit to PF03466, LysR substrate binding domain, score 8.5e-40 216591017892 2 probable transmembrane helices predicted for BCAM0020 by TMHMM2.0 at aa 21-43 and 48-70 216591017893 Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752 216591017894 Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209 216591017895 nucleophile elbow; other site 216591017896 Patatin phospholipase; Region: DUF3734; pfam12536 216591017897 HMMPfam hit to PF01734, Patatin-like phospholipase, score 1.4e-21 216591017898 3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK13394 216591017899 classical (c) SDRs; Region: SDR_c; cd05233 216591017900 NAD(P) binding site [chemical binding]; other site 216591017901 active site 216591017902 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.9e-30 216591017903 PS00061 Short-chain dehydrogenases/reductases family signature. 216591017904 acetoacetate decarboxylase; Provisional; Region: PRK02265 216591017905 HMMPfam hit to PF06314, Acetoacetate decarboxylase (ADC), score 5.2e-159 216591017906 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 216591017907 active site 216591017908 4 probable transmembrane helices predicted for BCAM0024 by TMHMM2.0 at aa 27-49, 56-78, 107-129 and 142-164 216591017909 HMMPfam hit to PF01569, PAP2 superfamily, score 3.6e-19 216591017910 1 probable transmembrane helix predicted for BCAM0025 by TMHMM2.0 at aa 37-59 216591017911 Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375 216591017912 Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193 216591017913 FAD binding pocket [chemical binding]; other site 216591017914 FAD binding motif [chemical binding]; other site 216591017915 phosphate binding motif [ion binding]; other site 216591017916 NAD binding pocket [chemical binding]; other site 216591017917 HMMPfam hit to PF04954, Siderophore-interacting protein, score 9.6e-42 216591017918 HMMPfam hit to PF08021, Siderophore-interacting FAD-binding dom, score 1.9e-55 216591017919 Predicted transcriptional regulators [Transcription]; Region: COG1695 216591017920 Transcriptional regulator PadR-like family; Region: PadR; pfam03551 216591017921 HMMPfam hit to PF03551, Transcriptional regulator PadR-like family, score 1.5e-28 216591017922 Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060 216591017923 phosphopeptide binding site; other site 216591017924 HMMPfam hit to PF00498, FHA domain, score 7e-13 216591017925 Predicted helix-turn-helix motif with score 1097.000, SD 2.92 at aa 266-287, sequence IELDRLARMLGIDASHVNVQIH 216591017926 Catalytic domain of Protein Kinases; Region: PKc; cd00180 216591017927 active site 216591017928 ATP binding site [chemical binding]; other site 216591017929 substrate binding site [chemical binding]; other site 216591017930 TOMM system kinase/cyclase fusion protein; Region: TOMM_kin_cyc; TIGR03903 216591017931 activation loop (A-loop); other site 216591017932 cyclase homology domain; Region: CHD; cd07302 216591017933 nucleotidyl binding site; other site 216591017934 metal binding site [ion binding]; metal-binding site 216591017935 AAA ATPase domain; Region: AAA_16; pfam13191 216591017936 HMMPfam hit to PF00069, Protein kinase domain, score 4.1e-45 216591017937 PS00107 Protein kinases ATP-binding region signature. 216591017938 PS00108 Serine/Threonine protein kinases active-site signature. 216591017939 PS00017 ATP/GTP-binding site motif A (P-loop). 216591017940 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 0.079 216591017941 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 0.024 216591017942 HMMPfam hit to PF07721, Tetratricopeptide repeat, score 0.058 216591017943 ribosomal natural product, two-chain TOMM family; Region: RNP_Burkhold; TIGR03795 216591017944 ribosomal natural product, two-chain TOMM family; Region: RNP_Burkhold; TIGR03795 216591017945 bacteriocin biosynthesis cyclodehydratase domain; Region: cyclo_dehyd_2; TIGR03882 216591017946 YcaO-like family; Region: YcaO; pfam02624 216591017947 thiazole/oxazole-forming peptide maturase, SagD family component; Region: TOMM_cyclo_SagD; TIGR03604 216591017948 HMMPfam hit to PF02624, YcaO-like family, score 7.8e-60 216591017949 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591017950 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591017951 trimer interface [polypeptide binding]; other site 216591017952 eyelet of channel; other site 216591017953 1 probable transmembrane helix predicted for BCAM0033 by TMHMM2.0 at aa 7-29 216591017954 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 216591017955 classical (c) SDRs; Region: SDR_c; cd05233 216591017956 NAD(P) binding site [chemical binding]; other site 216591017957 active site 216591017958 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00015 216591017959 HMMPfam hit to PF00106, short chain dehydrogenase, score 6.6e-15 216591017960 PS00061 Short-chain dehydrogenases/reductases family signature. 216591017961 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 216591017962 (2R,3R)-2,3-butanediol dehydrogenase; Region: butanediol_DH_like; cd08233 216591017963 putative NAD(P) binding site [chemical binding]; other site 216591017964 catalytic Zn binding site [ion binding]; other site 216591017965 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.5e-42 216591017966 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 1.1e-46 216591017967 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591017968 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591017969 D-galactonate transporter; Region: 2A0114; TIGR00893 216591017970 putative substrate translocation pore; other site 216591017971 HMMPfam hit to PF00083, Sugar (and other) transporter score 8.4e-05 216591017972 11 probable transmembrane helices predicted for BCAM0036 by TMHMM2.0 at aa 20-42, 55-74, 84-106, 148-170, 175-194, 230-252, 267-289, 296-313, 318-340, 352-374 and 384-406 216591017973 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017974 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.9e-55 216591017975 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017976 PS00217 Sugar transport proteins signature 2. 216591017977 Cupin domain; Region: Cupin_2; pfam07883 216591017978 HMMPfam hit to PF07883, Cupin domain, score 2.4e-05 216591017979 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591017980 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591017981 Predicted helix-turn-helix motif with score 1307.000, SD 3.64 at aa 234-255, sequence LGPQAVADAVGLSLRHLGRLFA 216591017982 PS00041 Bacterial regulatory proteins, araC family signature. 216591017983 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.9e-08 216591017984 choline dehydrogenase; Validated; Region: PRK02106 216591017985 putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834 216591017986 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 216591017987 HMMPfam hit to PF05199, GMC oxidoreductase, score 1.2e-43 216591017988 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00025 216591017989 HMMPfam hit to PF00732, GMC oxidoreductase, score 5.2e-90 216591017990 PS00624 GMC oxidoreductases signature 2. 216591017991 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591017992 PS00623 GMC oxidoreductases signature 1. 216591017993 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591017994 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591017995 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591017996 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3e-06 216591017997 Predicted helix-turn-helix motif with score 1078.000, SD 2.86 at aa 232-253, sequence LDSRSVSRAINLSPRQLARVFE 216591017998 1 probable transmembrane helix predicted for BCAM0041 by TMHMM2.0 at aa 21-40 216591017999 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018000 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591018001 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 216591018002 active site 216591018003 catalytic tetrad [active] 216591018004 HMMPfam hit to PF00248, Aldo/keto reductase family, score 2.6e-51 216591018005 Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501 216591018006 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 216591018007 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 216591018008 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 216591018009 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 216591018010 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 4.8e-21 216591018011 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 216591018012 Protein of unknown function (DUF3304); Region: DUF3304; pfam11745 216591018013 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018014 Uncharacterized conserved protein (DUF2235); Region: DUF2235; pfam09994 216591018015 Lysine efflux permease [General function prediction only]; Region: COG1279 216591018016 6 probable transmembrane helices predicted for BCAM0047 by TMHMM2.0 at aa 5-27, 40-62, 67-89, 122-144, 154-176 and 183-205 216591018017 HMMPfam hit to PF01810, LysE type translocator, score 4.1e-44 216591018018 chromosome replication initiation inhibitor protein; Validated; Region: PRK03635 216591018019 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591018020 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591018021 dimerization interface [polypeptide binding]; other site 216591018022 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.5e-14 216591018023 Predicted helix-turn-helix motif with score 2002.000, SD 6.01 at aa 17-38, sequence GSFERAAKELNVTPSAVSQRVK 216591018024 PS00044 Bacterial regulatory proteins, lysR family signature. 216591018025 PS00070 Aldehyde dehydrogenases cysteine active site. 216591018026 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.1e-09 216591018027 fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161 216591018028 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 216591018029 ligand binding site [chemical binding]; other site 216591018030 flexible hinge region; other site 216591018031 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 216591018032 putative switch regulator; other site 216591018033 non-specific DNA interactions [nucleotide binding]; other site 216591018034 DNA binding site [nucleotide binding] 216591018035 sequence specific DNA binding site [nucleotide binding]; other site 216591018036 putative cAMP binding site [chemical binding]; other site 216591018037 HMMPfam hit to PF00325, Bacterial regulatory proteins, crp famil, score 8.8e-15 216591018038 PS00042 Bacterial regulatory proteins, crp family signature. 216591018039 Predicted helix-turn-helix motif with score 1625.000, SD 4.72 at aa 201-222, sequence MTREDIGSYLGMTLETVSRTLS 216591018040 HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 4.9e-21 216591018041 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591018042 Ligand Binding Site [chemical binding]; other site 216591018043 HMMPfam hit to PF00582, Universal stress protein family, score 8.1e-24 216591018044 Protein of unknown function (DUF3005); Region: DUF3005; pfam11448 216591018045 serine O-acetyltransferase; Region: cysE; TIGR01172 216591018046 Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354 216591018047 trimer interface [polypeptide binding]; other site 216591018048 active site 216591018049 substrate binding site [chemical binding]; other site 216591018050 CoA binding site [chemical binding]; other site 216591018051 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.52 216591018052 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 11 216591018053 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 8.6 216591018054 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591018055 short chain dehydrogenase; Provisional; Region: PRK09134 216591018056 NAD(P) binding site [chemical binding]; other site 216591018057 active site 216591018058 HMMPfam hit to PF00106, short chain dehydrogenase, score 1e-07 216591018059 GTP cyclohydrolase I; Provisional; Region: folE; PRK09347 216591018060 GTP cyclohydrolase I; Provisional; Region: PLN03044 216591018061 active site 216591018062 HMMPfam hit to PF01227, GTP cyclohydrolase I, score 5.1e-44 216591018063 PS00859 GTP cyclohydrolase I signature 1. 216591018064 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591018065 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591018066 The C-terminal substrate binding domain of LysR-type transcriptional regulators that are involved in the catabolism of dinitrotoluene, naphthalene and gamma-hexachlorohexane; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_NahR_LinR_like; cd08459 216591018067 substrate binding pocket [chemical binding]; other site 216591018068 dimerization interface [polypeptide binding]; other site 216591018069 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.5e-23 216591018070 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.4e-18 216591018071 Predicted helix-turn-helix motif with score 1285.000, SD 3.56 at aa 19-40, sequence RNVSRAGDLLGVSQPRVSTALG 216591018072 4-hydroxybenzoate 3-monooxygenase; Validated; Region: PRK08243 216591018073 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591018074 HMMPfam hit to PF01494, FAD binding domain, score 5.7e-108 216591018075 Coenzyme A transferase; Region: CoA_trans; cl17247 216591018076 HMMPfam hit to PF01144, Coenzyme A transferase, score 1.1e-93 216591018077 PS01273 CoA transferases signature 1. 216591018078 3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428 216591018079 HMMPfam hit to PF01144, Coenzyme A transferase, score 2.7e-59 216591018080 PS01274 CoA transferases signature 2. 216591018081 3-carboxy-cis,cis-muconate cycloisomerase; Provisional; Region: PRK09053 216591018082 prokaryotic 3-carboxy-cis,cis-muconate cycloisomerase (CMLE)_like; Region: pCLME; cd01597 216591018083 tetramer interface [polypeptide binding]; other site 216591018084 active site 216591018085 HMMPfam hit to PF00206, Lyase, score 1.9e-53 216591018086 PS00163 Fumarate lyases signature. 216591018087 3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427 216591018088 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 8.7e-27 216591018089 4-carboxymuconolactone decarboxylase; Region: decarb_PcaC; TIGR02425 216591018090 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 7.5e-34 216591018091 benzoate transport; Region: 2A0115; TIGR00895 216591018092 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591018093 putative substrate translocation pore; other site 216591018094 HMMPfam hit to PF00083, Sugar (and other) transporter score 7.9e-07 216591018095 11 probable transmembrane helices predicted for BCAM0063 by TMHMM2.0 at aa 24-46, 61-83, 90-112, 117-136, 149-171, 175-197, 255-277, 292-314, 335-357, 380-402 and 409-431 216591018096 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.4e-48 216591018097 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018098 PS00216 Sugar transport proteins signature 1. 216591018099 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018100 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018101 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591018102 5 probable transmembrane helices predicted for BCAM0065 by TMHMM2.0 at aa 3-22, 42-64, 71-93, 147-169 and 182-204 216591018103 HMMPfam hit to PF01810, LysE type translocator, score 4.8e-05 216591018104 Similar to the N-terminal region of Burkholderia cepacia insertion element IS402 hypothetical 16.2 kDa protein SWALL:YI22_BURCE (SWALL:P24537) (147 aa) fasta scores: E(): 1e-07, 45.78% id in 83 aa 216591018105 FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454 216591018106 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018107 PS00215 Mitochondrial energy transfer proteins signature. 216591018108 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591018109 short chain dehydrogenase; Provisional; Region: PRK07041 216591018110 NAD(P) binding site [chemical binding]; other site 216591018111 active site 216591018112 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.8e-07 216591018113 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0033 216591018114 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591018115 14 probable transmembrane helices predicted for BCAM0068 by TMHMM2.0 at aa 32-54, 74-93, 100-122, 126-143, 156-178, 182-204, 216-238, 248-270, 283-305, 320-339, 346-368, 378-400, 421-438 and 442-464 216591018116 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.4e-54 216591018117 GH3 auxin-responsive promoter; Region: GH3; pfam03321 216591018118 HMMPfam hit to PF03321, GH3 auxin-responsive promoter, score 1.9e-09 216591018119 Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267 216591018120 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591018121 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 0.00025 216591018122 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948 216591018123 Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188 216591018124 metal binding site [ion binding]; metal-binding site 216591018125 substrate binding pocket [chemical binding]; other site 216591018126 HMMPfam hit to PF01188, Mandelate racemase / muconate lactonizing en, score 5.4e-08 216591018127 PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 216591018128 acetolactate synthase catalytic subunit; Validated; Region: PRK08327 216591018129 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 216591018130 PYR/PP interface [polypeptide binding]; other site 216591018131 dimer interface [polypeptide binding]; other site 216591018132 TPP binding site [chemical binding]; other site 216591018133 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591018134 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629 216591018135 TPP-binding site [chemical binding]; other site 216591018136 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 1.6e-08 216591018137 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 3.1e-22 216591018138 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 216591018139 transcriptional repressor BetI; Region: betaine_BetI; TIGR03384 216591018140 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591018141 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.7e-17 216591018142 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591018143 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591018144 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.9e-13 216591018145 3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183 216591018146 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591018147 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591018148 HMMPfam hit to PF01494, FAD binding domain, score 2.3e-59 216591018149 PS00017 ATP/GTP-binding site motif A (P-loop). 216591018150 N-terminal domain of 2,4,5-trihydroxytoluene (THT) oxygenase; Region: THT_Oxygenase_N; cd07267 216591018151 3,4-dihydroxyphenylacetate 2,3-dioxygenase; Region: HpaD; TIGR02295 216591018152 The C-terminal domain of 2,4,5-Trihydroxytoluene (THT) oxygenase, which is an extradiol dioxygenease in the 2,4-dinitrotoluene (DNT) degradation pathway; Region: THT_oxygenase_C; cd07257 216591018153 putative active site [active] 216591018154 putative metal binding site [ion binding]; other site 216591018155 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 0.0017 216591018156 Domain of unknown function (DUF2437); Region: DUF2437; pfam10370 216591018157 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 216591018158 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 216591018159 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 6.9e-36 216591018160 AMP-binding domain protein; Validated; Region: PRK07529 216591018161 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591018162 Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_4; cd05944 216591018163 acyl-activating enzyme (AAE) consensus motif; other site 216591018164 putative AMP binding site [chemical binding]; other site 216591018165 putative active site [active] 216591018166 putative CoA binding site [chemical binding]; other site 216591018167 HMMPfam hit to PF00501, AMP-binding enzyme, score 8.4e-79 216591018168 PS00455 Putative AMP-binding domain signature. 216591018169 PS00017 ATP/GTP-binding site motif A (P-loop). 216591018170 Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047 216591018171 HMMPfam hit to PF03922, OmpW family, score 1.2e-17 216591018172 Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726 216591018173 Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918 216591018174 putative active site [active] 216591018175 putative metal binding site [ion binding]; other site 216591018176 HMMPfam hit to PF01522, Polysaccharide deacetylase, score 4.6e-26 216591018177 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591018178 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 216591018179 HMMPfam hit to PF00534, Glycosyl transferases group, score 5e-18 216591018180 transcriptional repressor BetI; Region: betaine_BetI; TIGR03384 216591018181 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591018182 Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977 216591018183 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 4.5e-16 216591018184 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 216591018185 Sodium:dicarboxylate symporter family; Region: SDF; pfam00375 216591018186 HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 4e-110 216591018187 7 probable transmembrane helices predicted for BCAM0086 by TMHMM2.0 at aa 7-29, 56-78, 85-107, 154-171, 192-214, 227-249 and 315-337 216591018188 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018189 SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450 216591018190 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018191 PS00017 ATP/GTP-binding site motif A (P-loop). 216591018192 PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145 216591018193 HMMPfam hit to PF00639, PPIC-type PPIASE domain, score 0.00011 216591018194 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 216591018195 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591018196 Coenzyme A binding pocket [chemical binding]; other site 216591018197 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.5e-08 216591018198 MASE1; Region: MASE1; pfam05231 216591018199 PAS fold; Region: PAS_3; pfam08447 216591018200 8 probable transmembrane helices predicted for BCAM0091 by TMHMM2.0 at aa 9-26, 36-54, 59-76, 80-102, 114-136, 151-173, 186-204 and 214-236 216591018201 HMMPfam hit to PF05231, MASE1, score 2.6e-41 216591018202 HMMPfam hit to PF08447, PAS fold, score 0.0013 216591018203 Esterase/lipase [General function prediction only]; Region: COG1647 216591018204 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 216591018205 Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592 216591018206 DNA binding residues [nucleotide binding] 216591018207 PS00017 ATP/GTP-binding site motif A (P-loop). 216591018208 HMMPfam hit to PF00376, MerR family regulatory protein, score 3.9e-09 216591018209 PS00552 Bacterial regulatory proteins, merR family signature. 216591018210 Predicted helix-turn-helix motif with score 1159.000, SD 3.13 at aa 8-29, sequence LNASAAAARLGVSIKALRLYER 216591018211 Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808 216591018212 N- and C-terminal domain interface [polypeptide binding]; other site 216591018213 D-xylulose kinase; Region: XylB; TIGR01312 216591018214 active site 216591018215 MgATP binding site [chemical binding]; other site 216591018216 catalytic site [active] 216591018217 metal binding site [ion binding]; metal-binding site 216591018218 xylulose binding site [chemical binding]; other site 216591018219 homodimer interface [polypeptide binding]; other site 216591018220 HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 4.3e-45 216591018221 PS00445 FGGY family of carbohydrate kinases signature 2. 216591018222 HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 6.1e-87 216591018223 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 216591018224 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591018225 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591018226 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.0001 216591018227 PS00041 Bacterial regulatory proteins, araC family signature. 216591018228 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.4e-05 216591018229 Predicted helix-turn-helix motif with score 1306.000, SD 3.64 at aa 198-219, sequence LREADVAAFAGMSVSTFTRFFR 216591018230 glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650 216591018231 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 216591018232 Walker A/P-loop; other site 216591018233 ATP binding site [chemical binding]; other site 216591018234 Q-loop/lid; other site 216591018235 ABC transporter signature motif; other site 216591018236 Walker B; other site 216591018237 D-loop; other site 216591018238 H-loop/switch region; other site 216591018239 HMMPfam hit to PF08402, TOBE domain, score 1.1e-14 216591018240 HMMPfam hit to PF03459, TOBE domain, score 1.9e-05 216591018241 HMMPfam hit to PF00005, ABC transporter score 6.6e-59 216591018242 PS00211 ABC transporters family signature. 216591018243 PS00017 ATP/GTP-binding site motif A (P-loop). 216591018244 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 216591018245 Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285 216591018246 inhibitor binding site; inhibition site 216591018247 catalytic Zn binding site [ion binding]; other site 216591018248 structural Zn binding site [ion binding]; other site 216591018249 NADP binding site [chemical binding]; other site 216591018250 tetramer interface [polypeptide binding]; other site 216591018251 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 8.9e-24 216591018252 1 probable transmembrane helix predicted for BCAM0097 by TMHMM2.0 at aa 168-190 216591018253 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 1.6e-34 216591018254 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591018255 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 216591018256 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591018257 dimer interface [polypeptide binding]; other site 216591018258 conserved gate region; other site 216591018259 putative PBP binding loops; other site 216591018260 ABC-ATPase subunit interface; other site 216591018261 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3.7e-06 216591018262 6 probable transmembrane helices predicted for BCAM0098 by TMHMM2.0 at aa 7-29, 73-95, 107-129, 139-161, 181-203 and 239-261 216591018263 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591018264 ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175 216591018265 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.00053 216591018266 6 probable transmembrane helices predicted for BCAM0099 by TMHMM2.0 at aa 38-60, 99-121, 145-167, 182-204, 225-247 and 289-311 216591018267 PS00211 ABC transporters family signature. 216591018268 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 216591018269 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 216591018270 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 7.4e-25 216591018271 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018272 Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618 216591018273 Amidohydrolase; Region: Amidohydro_2; pfam04909 216591018274 HMMPfam hit to PF04909, Amidohydrolase, score 1.4e-33 216591018275 Uncharacterized conserved protein [Function unknown]; Region: COG3391 216591018276 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591018277 D-galactonate transporter; Region: 2A0114; TIGR00893 216591018278 putative substrate translocation pore; other site 216591018279 HMMPfam hit to PF00083, Sugar (and other) transporter score 0.00019 216591018280 12 probable transmembrane helices predicted for BCAM0103 by TMHMM2.0 at aa 22-44, 59-78, 91-113, 117-139, 152-174, 178-200, 248-270, 285-307, 314-336, 340-362, 375-397 and 402-424 216591018281 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.8e-67 216591018282 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018283 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018284 Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329 216591018285 Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408 216591018286 inhibitor site; inhibition site 216591018287 active site 216591018288 dimer interface [polypeptide binding]; other site 216591018289 catalytic residue [active] 216591018290 HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 3.3e-10 216591018291 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948 216591018292 Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327 216591018293 putative active site pocket [active] 216591018294 putative metal binding site [ion binding]; other site 216591018295 HMMPfam hit to PF01188, Mandelate racemase / muconate lactonizing en, score 1.4e-09 216591018296 HMMPfam hit to PF02746, Mandelate racemase / muconate lactonizing en, score 2.9e-21 216591018297 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232 216591018298 4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743 216591018299 HMMPfam hit to PF04166, Pyridoxal phosphate biosynthetic protein Pdx, score 2e-96 216591018300 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591018301 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591018302 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591018303 dimerization interface [polypeptide binding]; other site 216591018304 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.3e-20 216591018305 Predicted helix-turn-helix motif with score 1421.000, SD 4.03 at aa 32-53, sequence STLRAAAEQMGLTQPAATKMLA 216591018306 PS00044 Bacterial regulatory proteins, lysR family signature. 216591018307 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.2e-27 216591018308 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591018309 D-galactonate transporter; Region: 2A0114; TIGR00893 216591018310 putative substrate translocation pore; other site 216591018311 HMMPfam hit to PF00083, Sugar (and other) transporter score 0.00026 216591018312 10 probable transmembrane helices predicted for BCAM0108 by TMHMM2.0 at aa 12-34, 47-69, 76-98, 163-185, 222-244, 254-276, 289-311, 316-338, 351-373 and 378-400 216591018313 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.1e-59 216591018314 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018315 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 216591018316 4 probable transmembrane helices predicted for BCAM0109 by TMHMM2.0 at aa 32-54, 58-80, 106-128 and 143-165 216591018317 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591018318 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591018319 dimer interface [polypeptide binding]; other site 216591018320 phosphorylation site [posttranslational modification] 216591018321 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591018322 Mg2+ binding site [ion binding]; other site 216591018323 G-X-G motif; other site 216591018324 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3e-34 216591018325 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5e-11 216591018326 HMMPfam hit to PF00672, HAMP domain, score 2.2e-09 216591018327 2 probable transmembrane helices predicted for BCAM0110 by TMHMM2.0 at aa 12-34 and 56-78 216591018328 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591018329 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591018330 active site 216591018331 phosphorylation site [posttranslational modification] 216591018332 intermolecular recognition site; other site 216591018333 dimerization interface [polypeptide binding]; other site 216591018334 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591018335 DNA binding site [nucleotide binding] 216591018336 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.2e-14 216591018337 HMMPfam hit to PF00072, Response regulator receiver domain, score 7.5e-36 216591018338 Monoamine oxidase [Amino acid transport and metabolism]; Region: COG1231 216591018339 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 216591018340 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00058 216591018341 HMMPfam hit to PF01593, Flavin containing amine oxidoreductase, score 1.7e-42 216591018342 Cytochrome c; Region: Cytochrom_C; cl11414 216591018343 Cytochrome c; Region: Cytochrom_C; cl11414 216591018344 1 probable transmembrane helix predicted for BCAM0113 by TMHMM2.0 at aa 12-34 216591018345 HMMPfam hit to PF00034, Cytochrome c, score 0.022 216591018346 PS00190 Cytochrome c family heme-binding site signature. 216591018347 HMMPfam hit to PF00034, Cytochrome c, score 0.017 216591018348 PS00190 Cytochrome c family heme-binding site signature. 216591018349 7 probable transmembrane helices predicted for BCAM0114 by TMHMM2.0 at aa 5-24, 31-53, 68-90, 97-116, 120-142, 149-171 and 181-203 216591018350 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591018351 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 6.3e-14 216591018352 Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312 216591018353 HMMPfam hit to PF05721, Phytanoyl-CoA dioxygenase (PhyH), score 4.6e-06 216591018354 YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198 216591018355 homotrimer interaction site [polypeptide binding]; other site 216591018356 putative active site [active] 216591018357 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 4.2e-31 216591018358 Protein of unknown function (DUF1329); Region: DUF1329; pfam07044 216591018359 HMMPfam hit to PF07044, Protein of unknown function (DUF1329), score 2.9e-114 216591018360 1 probable transmembrane helix predicted for BCAM0118 by TMHMM2.0 at aa 7-26 216591018361 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018362 Protein of unknown function (DUF1302); Region: DUF1302; pfam06980 216591018363 HMMPfam hit to PF06980, Protein of unknown function (DUF1302), score 5e-79 216591018364 Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033 216591018365 12 probable transmembrane helices predicted for BCAM0120 by TMHMM2.0 at aa 13-35, 227-249, 254-273, 283-305, 326-348, 363-385, 414-431, 618-635, 642-659, 669-688, 709-731 and 746-768 216591018366 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018367 PS00306 Caseins alpha/beta signature. 216591018368 Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447 216591018369 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.51 216591018370 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 7.7 216591018371 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 13 216591018372 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 2.8 216591018373 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.12 216591018374 Monoamine oxidase [Amino acid transport and metabolism]; Region: COG1231 216591018375 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2.7e-06 216591018376 HMMPfam hit to PF01593, Flavin containing amine oxidoreductase, score 1.3e-46 216591018377 Cytochrome c; Region: Cytochrom_C; cl11414 216591018378 Cytochrome c; Region: Cytochrom_C; cl11414 216591018379 1 probable transmembrane helix predicted for BCAM0124 by TMHMM2.0 at aa 5-27 216591018380 PS00190 Cytochrome c family heme-binding site signature. 216591018381 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591018382 NAD(P) binding site [chemical binding]; other site 216591018383 HMMPfam hit to PF03435, Saccharopine dehydrogenase, score 4.9e-07 216591018384 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 216591018385 acyl-CoA synthetase; Validated; Region: PRK06188 216591018386 Bacterial Bile acid CoA ligases and similar proteins; Region: BACL_like; cd05929 216591018387 acyl-activating enzyme (AAE) consensus motif; other site 216591018388 putative AMP binding site [chemical binding]; other site 216591018389 putative active site [active] 216591018390 putative CoA binding site [chemical binding]; other site 216591018391 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.2e-111 216591018392 PS00455 Putative AMP-binding domain signature. 216591018393 lipid-transfer protein; Provisional; Region: PRK08256 216591018394 Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal...; Region: SCP-x_thiolase; cd00829 216591018395 active site 216591018396 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 1e-06 216591018397 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591018398 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591018399 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.5e-85 216591018400 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591018401 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591018402 Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977 216591018403 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.2e-08 216591018404 Predicted helix-turn-helix motif with score 1673.000, SD 4.89 at aa 53-74, sequence FSQRAVAAAAGISVSNLQYYFP 216591018405 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591018406 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591018407 active site 216591018408 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 3e-20 216591018409 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 6.5e-09 216591018410 chaperone protein HchA; Provisional; Region: PRK04155 216591018411 Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020 216591018412 conserved cys residue [active] 216591018413 HMMPfam hit to PF01965, DJ-1/PfpI family, score 0.0028 216591018414 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06187 216591018415 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591018416 acyl-activating enzyme (AAE) consensus motif; other site 216591018417 AMP binding site [chemical binding]; other site 216591018418 active site 216591018419 CoA binding site [chemical binding]; other site 216591018420 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.9e-86 216591018421 ATP-dependent transcriptional regulator [Transcription]; Region: MalT; COG2909 216591018422 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591018423 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591018424 DNA binding residues [nucleotide binding] 216591018425 dimerization interface [polypeptide binding]; other site 216591018426 PS00017 ATP/GTP-binding site motif A (P-loop). 216591018427 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018428 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 6.8e-20 216591018429 PS00622 Bacterial regulatory proteins, luxR family signature. 216591018430 Predicted helix-turn-helix motif with score 1736.000, SD 5.10 at aa 869-890, sequence LSNKEIARALRVAPETIKWHLK 216591018431 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591018432 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591018433 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591018434 dimerization interface [polypeptide binding]; other site 216591018435 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.4e-38 216591018436 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.2e-18 216591018437 Predicted helix-turn-helix motif with score 1474.000, SD 4.21 at aa 16-37, sequence RTLRRAAQTLGVDQATVGRRLA 216591018438 PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276 216591018439 putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824 216591018440 NAD(P) binding site [chemical binding]; other site 216591018441 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 1.2e-23 216591018442 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2e-39 216591018443 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591018444 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591018445 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591018446 putative effector binding pocket; other site 216591018447 dimerization interface [polypeptide binding]; other site 216591018448 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.3e-14 216591018449 Predicted helix-turn-helix motif with score 1361.000, SD 3.82 at aa 17-38, sequence GSFSAVAKQTDVATAQVSRAVA 216591018450 HMMPfam hit to PF03466, LysR substrate binding domain, score 1e-33 216591018451 BON domain; Region: BON; cl02771 216591018452 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 216591018453 catalytic core [active] 216591018454 HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 2.9e-15 216591018455 Acyl-CoA dehydrogenase (ACAD) 10 and 11, N-terminal domain, and similar proteins. This subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs); Region: ACAD10_11_like; cd05154 216591018456 Phosphotransferase enzyme family; Region: APH; pfam01636 216591018457 putative active site [active] 216591018458 putative substrate binding site [chemical binding]; other site 216591018459 ATP binding site [chemical binding]; other site 216591018460 HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 1.3e-51 216591018461 PS00109 Tyrosine protein kinases specific active-site signature. 216591018462 short chain dehydrogenase; Provisional; Region: PRK07035 216591018463 classical (c) SDRs; Region: SDR_c; cd05233 216591018464 NAD(P) binding site [chemical binding]; other site 216591018465 active site 216591018466 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.6e-28 216591018467 PS00061 Short-chain dehydrogenases/reductases family signature. 216591018468 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231 216591018469 classical (c) SDRs; Region: SDR_c; cd05233 216591018470 NAD(P) binding site [chemical binding]; other site 216591018471 active site 216591018472 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.9e-26 216591018473 PS00061 Short-chain dehydrogenases/reductases family signature. 216591018474 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591018475 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591018476 active site 216591018477 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 3.1e-23 216591018478 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 1.2e-43 216591018479 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 9.2e-07 216591018480 leucine transcriptional activator; Reviewed; Region: leuO; PRK09508 216591018481 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591018482 The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417 216591018483 substrate binding pocket [chemical binding]; other site 216591018484 dimerization interface [polypeptide binding]; other site 216591018485 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.1e-19 216591018486 Predicted helix-turn-helix motif with score 1798.000, SD 5.31 at aa 21-42, sequence RNLTRAAEVLNLTQPAVSNALA 216591018487 PS00044 Bacterial regulatory proteins, lysR family signature. 216591018488 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.9e-18 216591018489 DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257 216591018490 HSP70 interaction site [polypeptide binding]; other site 216591018491 HMMPfam hit to PF00226, DnaJ domain, score 0.0049 216591018492 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591018493 1 probable transmembrane helix predicted for BCAM0145 by TMHMM2.0 at aa 5-27 216591018494 DNA polymerase II; Reviewed; Region: PRK05762 216591018495 DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784 216591018496 active site 216591018497 catalytic site [active] 216591018498 substrate binding site [chemical binding]; other site 216591018499 DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537 216591018500 active site 216591018501 metal-binding site 216591018502 HMMPfam hit to PF00136, DNA polymerase family B, score 1.3e-27 216591018503 PS00116 DNA polymerase family B signature. 216591018504 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018505 HMMPfam hit to PF03104, DNA polymerase family B, exonuclease do, score 5.9e-16 216591018506 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591018507 Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501 216591018508 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 216591018509 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 216591018510 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 216591018511 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 216591018512 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 2.7e-27 216591018513 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 216591018514 Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502 216591018515 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 216591018516 putative active site [active] 216591018517 catalytic site [active] 216591018518 Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502 216591018519 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 216591018520 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 216591018521 putative active site [active] 216591018522 catalytic site [active] 216591018523 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018524 PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 216591018525 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 0.5 216591018526 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 0.0036 216591018527 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 216591018528 Sel1-like repeats; Region: SEL1; smart00671 216591018529 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018530 HMMPfam hit to PF08238, Sel1 repeat, score 1.1e-06 216591018531 Probable gene remnant. Similar to the N-terminal region of Neisseria meningitidis hypothetical protein NMB1470 SWALL:Q9JYR0 (EMBL:AE002496) (181 aa) fasta scores: E(): 3.7, 46.51% id in 43 aa 216591018532 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018533 Probable gene remnant. Similar to the C-terminal region of Ralstonia solanacearum probable phospholipase rs03737 SWALL:Q8XS51 (EMBL:AL646079) (652 aa) fasta scores: E(): 1e-16, 50% id in 120 aa 216591018534 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 216591018535 Sel1-like repeats; Region: SEL1; smart00671 216591018536 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018537 HMMPfam hit to PF08238, Sel1 repeat, score 4.4e-08 216591018538 2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274 216591018539 HMMPfam hit to PF03812, 2-keto-3-deoxygluconate permease, score 4.4e-198 216591018540 10 probable transmembrane helices predicted for BCAM0153 by TMHMM2.0 at aa 13-32, 42-64, 77-96, 106-128, 141-163, 168-187, 194-216, 226-244, 251-273 and 283-305 216591018541 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018542 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591018543 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018544 5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924 216591018545 HMMPfam hit to PF04962, 5-keto 4-deoxyuronate isomerase, score 7.2e-176 216591018546 2-deoxy-D-gluconate 3-dehydrogenase; Region: kduD; TIGR01832 216591018547 gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347 216591018548 NADP binding site [chemical binding]; other site 216591018549 homodimer interface [polypeptide binding]; other site 216591018550 active site 216591018551 HMMPfam hit to PF00106, short chain dehydrogenase, score 7.5e-29 216591018552 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018553 PS00061 Short-chain dehydrogenases/reductases family signature. 216591018554 DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090 216591018555 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591018556 putative DNA binding site [nucleotide binding]; other site 216591018557 putative Zn2+ binding site [ion binding]; other site 216591018558 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591018559 HMMPfam hit to PF08279, HTH domain, score 0.0022 216591018560 Predicted helix-turn-helix motif with score 1838.000, SD 5.45 at aa 57-78, sequence IGISELSHQLGMSKTTVHRFLQ 216591018561 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 7e-46 216591018562 PS01051 Bacterial regulatory proteins, iclR family signature. 216591018563 Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943 216591018564 CSS motif domain associated with EAL; Region: CSS-motif; pfam12792 216591018565 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 216591018566 HMMPfam hit to PF00563, EAL domain, score 2.5e-84 216591018567 2 probable transmembrane helices predicted for BCAM0158 by TMHMM2.0 at aa 4-20 and 229-251 216591018568 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 216591018569 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591018570 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591018571 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.4e-07 216591018572 Predicted helix-turn-helix motif with score 1299.000, SD 3.61 at aa 254-275, sequence VSIEQIASDLHVSSRTLHRRLA 216591018573 Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000 216591018574 Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116 216591018575 4 probable transmembrane helices predicted for BCAM0162 by TMHMM2.0 at aa 15-37, 58-80, 90-109 and 142-161 216591018576 4 probable transmembrane helices predicted for BCAM0163 by TMHMM2.0 at aa 21-38, 42-64, 71-90 and 94-116 216591018577 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018578 Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399 216591018579 HMMPfam hit to PF00328, Histidine acid phosphatase, score 0.00035 216591018580 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018581 pyrophosphatase PpaX; Provisional; Region: PRK13288 216591018582 NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252 216591018583 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591018584 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.0016 216591018585 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 1.9e-16 216591018586 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 2e-12 216591018587 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591018588 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591018589 The C-terminal substrate binding of LysR-type transcriptional regulator (CbbR) of RubisCO operon, which is involved in the carbon dioxide fixation, contains the type 2 periplasmic binding fold; Region: PBP2_CbbR_RubisCO_like; cd08419 216591018590 putative dimerization interface [polypeptide binding]; other site 216591018591 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1e-21 216591018592 Predicted helix-turn-helix motif with score 1382.000, SD 3.89 at aa 24-45, sequence GSVSRAAEELNLTQPAVSLQVR 216591018593 PS00044 Bacterial regulatory proteins, lysR family signature. 216591018594 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.7e-55 216591018595 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591018596 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591018597 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591018598 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 8.8e-07 216591018599 Predicted helix-turn-helix motif with score 1440.000, SD 4.09 at aa 202-223, sequence MTLAELAALVSISVPHFKVLFR 216591018600 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.2e-06 216591018601 Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702 216591018602 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591018603 NAD(P) binding site [chemical binding]; other site 216591018604 active site 216591018605 HMMPfam hit to PF05368, NmrA-like family, score 0.0016 216591018606 benzoate transporter; Region: benE; TIGR00843 216591018607 Benzoate membrane transport protein; Region: BenE; pfam03594 216591018608 12 probable transmembrane helices predicted for BCAM0170 by TMHMM2.0 at aa 21-43, 53-72, 79-101, 105-124, 131-153, 157-176, 181-203, 223-245, 265-287, 302-324, 329-351 and 371-393 216591018609 HMMPfam hit to PF03594, Benzoate membrane transport protein, score 1.4e-204 216591018610 HMMPfam hit to PF00860, Permease family, score 0.0024 216591018611 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018612 Fatty acid desaturase protein family subgroup, a delta-12 acyl-lipid desaturase-like, DesA-like, yet uncharacterized subgroup of membrane fatty acid desaturase proteins found in alpha-, beta-, and gamma-proteobacteria. Sequences of this domain family...; Region: DesA_FADS-like; cd03509 216591018613 Fatty acid desaturase; Region: FA_desaturase; pfam00487 216591018614 putative di-iron ligands [ion binding]; other site 216591018615 HMMPfam hit to PF00487, Fatty acid desaturase, score 8.9e-08 216591018616 3 probable transmembrane helices predicted for BCAM0171 by TMHMM2.0 at aa 26-46, 180-202 and 206-228 216591018617 ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PhnD; COG3221 216591018618 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018619 ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776 216591018620 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 216591018621 ATP binding site [chemical binding]; other site 216591018622 Mg++ binding site [ion binding]; other site 216591018623 motif III; other site 216591018624 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591018625 nucleotide binding region [chemical binding]; other site 216591018626 ATP-binding site [chemical binding]; other site 216591018627 RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501 216591018628 putative RNA binding site [nucleotide binding]; other site 216591018629 HMMPfam hit to PF03880, DbpA RNA binding domain, score 5.2e-22 216591018630 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 7.7e-28 216591018631 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1.6e-68 216591018632 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 216591018633 PS00017 ATP/GTP-binding site motif A (P-loop). 216591018634 malate:quinone oxidoreductase; Validated; Region: PRK05257 216591018635 malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320 216591018636 HMMPfam hit to PF06039, Malate:quinone oxidoreductase (Mqo), score 0 216591018637 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.0001 216591018638 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018639 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591018640 AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404 216591018641 AsnC family; Region: AsnC_trans_reg; pfam01037 216591018642 HMMPfam hit to PF01037, AsnC family, score 1.5e-25 216591018643 Histone deacetylase class IIa; Region: HDAC_classII_APAH; cd10001 216591018644 Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123 216591018645 active site 216591018646 Zn binding site [ion binding]; other site 216591018647 HMMPfam hit to PF00850, Histone deacetylase domain, score 4.1e-60 216591018648 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591018649 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 216591018650 dimerization interface [polypeptide binding]; other site 216591018651 ligand binding site [chemical binding]; other site 216591018652 HMMPfam hit to PF01094, Receptor family ligand binding region, score 2.5e-57 216591018653 Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668 216591018654 Mechanosensitive ion channel; Region: MS_channel; pfam00924 216591018655 HMMPfam hit to PF00924, Mechanosensitive ion channel, score 5.4e-56 216591018656 3 probable transmembrane helices predicted for BCAM0179 by TMHMM2.0 at aa 13-35, 59-81 and 88-110 216591018657 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 216591018658 Peptidase family M23; Region: Peptidase_M23; pfam01551 216591018659 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591018660 HMMPfam hit to PF01551, Peptidase family M23, score 3.4e-41 216591018661 Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153 216591018662 putative heme binding pocket [chemical binding]; other site 216591018663 1 probable transmembrane helix predicted for BCAM0181 by TMHMM2.0 at aa 13-35 216591018664 HMMPfam hit to PF00199, Catalase, score 2.2e-06 216591018665 PS00287 Cysteine proteases inhibitors signature. 216591018666 Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038 216591018667 HMMPfam hit to PF01292, Cytochrome b561 family, score 6e-40 216591018668 4 probable transmembrane helices predicted for BCAM0182 by TMHMM2.0 at aa 21-43, 48-70, 97-119 and 150-172 216591018669 Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; cl15373 216591018670 Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344 216591018671 outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414 216591018672 Autotransporter beta-domain; Region: Autotransporter; pfam03797 216591018673 1 probable transmembrane helix predicted for BCAM0183 by TMHMM2.0 at aa 7-29 216591018674 HMMPfam hit to PF05594, no description, score 0.2 216591018675 HMMPfam hit to PF03212, Pertactin, score 0.0003 216591018676 HMMPfam hit to PF03797, Autotransporter beta-domain, score 3.4e-34 216591018677 Fucose-binding lectin II (PA-IIL); Region: PA-IIL; pfam07472 216591018678 HMMPfam hit to PF07472, Fucose-binding lectin II (PA-IIL), score 6.8e-41 216591018679 N-Terminal Domain Of Bc2l-C Lectin; Region: Bc2l-C_N; cd12211 216591018680 trimer interface [polypeptide binding]; other site 216591018681 ligand binding site [chemical binding]; other site 216591018682 Fucose-binding lectin II (PA-IIL); Region: PA-IIL; pfam07472 216591018683 HMMPfam hit to PF07472, Fucose-binding lectin II (PA-IIL), score 8.8e-39 216591018684 Fucose-binding lectin II (PA-IIL); Region: PA-IIL; pfam07472 216591018685 HMMPfam hit to PF07472, Fucose-binding lectin II (PA-IIL), score 2.8e-18 216591018686 2-isopropylmalate synthase; Validated; Region: PRK03739 216591018687 Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942 216591018688 active site 216591018689 catalytic residues [active] 216591018690 metal binding site [ion binding]; metal-binding site 216591018691 LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917 216591018692 PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 216591018693 HMMPfam hit to PF00682, HMGL-like, score 1e-92 216591018694 PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 216591018695 HMMPfam hit to PF08502, LeuA allosteric (dimerisation) domain, score 1.8e-25 216591018696 Autoinducer binding domain; Region: Autoind_bind; pfam03472 216591018697 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591018698 DNA binding residues [nucleotide binding] 216591018699 dimerization interface [polypeptide binding]; other site 216591018700 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 1.7e-16 216591018701 PS00622 Bacterial regulatory proteins, luxR family signature. 216591018702 Predicted helix-turn-helix motif with score 1238.000, SD 3.40 at aa 191-212, sequence KTAYEIGMIFGIAERTVKFHLQ 216591018703 PS00017 ATP/GTP-binding site motif A (P-loop). 216591018704 HMMPfam hit to PF03472, Autoinducer binding domain, score 3.5e-27 216591018705 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 216591018706 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591018707 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591018708 HMMPfam hit to PF02311, AraC-like ligand binding domain, score 3.6e-08 216591018709 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591018710 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 3.5e-05 216591018711 PS00041 Bacterial regulatory proteins, araC family signature. 216591018712 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 4.7e-07 216591018713 hypothetical protein; Provisional; Region: PRK07481 216591018714 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591018715 inhibitor-cofactor binding pocket; inhibition site 216591018716 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591018717 catalytic residue [active] 216591018718 HMMPfam hit to PF00202, Aminotransferase class-III, score 4.2e-125 216591018719 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591018720 Condensation domain; Region: Condensation; pfam00668 216591018721 HMMPfam hit to PF00668, Condensation domain, score 2.1e-11 216591018722 Protein of unknown function (DUF3050); Region: DUF3050; pfam11251 216591018723 ChrR Cupin-like domain; Region: Cupin_7; pfam12973 216591018724 HMMPfam hit to PF07883, Cupin domain, score 0.00016 216591018725 P-aminobenzoate N-oxygenase AurF; Region: AurF; pfam11583 216591018726 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 216591018727 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 216591018728 acyl-activating enzyme (AAE) consensus motif; other site 216591018729 AMP binding site [chemical binding]; other site 216591018730 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 216591018731 thioester reductase domain; Region: Thioester-redct; TIGR01746 216591018732 extended (e) SDRs, subgroup 1; Region: SDR_e1; cd05235 216591018733 putative NAD(P) binding site [chemical binding]; other site 216591018734 active site 216591018735 putative substrate binding site [chemical binding]; other site 216591018736 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.9e-133 216591018737 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.6e-14 216591018738 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 2e-05 216591018739 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 0.0028 216591018740 Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins; Region: PYR_PYL_RCAR_like; cd07821 216591018741 putative hydrophobic ligand binding site [chemical binding]; other site 216591018742 protein interface [polypeptide binding]; other site 216591018743 gate; other site 216591018744 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591018745 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591018746 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591018747 putative effector binding pocket; other site 216591018748 dimerization interface [polypeptide binding]; other site 216591018749 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.3e-43 216591018750 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.6e-15 216591018751 Predicted helix-turn-helix motif with score 1734.000, SD 5.09 at aa 11-32, sequence GTFTETGKRLGITTAHVSRLVA 216591018752 Cupin domain; Region: Cupin_2; pfam07883 216591018753 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591018754 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591018755 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 7e-06 216591018756 PS00041 Bacterial regulatory proteins, araC family signature. 216591018757 Predicted helix-turn-helix motif with score 1603.000, SD 4.65 at aa 173-194, sequence VTLQAWARDAHMNERTLARAFK 216591018758 HMMPfam hit to PF02311, AraC-like ligand binding domain, score 0.00094 216591018759 HMMPfam hit to PF07883, Cupin domain, score 1.1e-06 216591018760 Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538 216591018761 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018762 HMMPfam hit to PF02321, Outer membrane efflux protein, score 5.8e-27 216591018763 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.7e-29 216591018764 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591018765 Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566 216591018766 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591018767 1 probable transmembrane helix predicted for BCAM0200 by TMHMM2.0 at aa 20-42 216591018768 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.6e-44 216591018769 PS00850 Glycine radical signature. 216591018770 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591018771 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591018772 putative substrate translocation pore; other site 216591018773 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591018774 14 probable transmembrane helices predicted for BCAM0201 by TMHMM2.0 at aa 15-37, 57-79, 83-105, 112-134, 144-166, 173-195, 210-227, 240-258, 278-300, 313-332, 342-361, 374-396, 406-428 and 497-519 216591018775 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018776 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.9e-56 216591018777 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018778 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018779 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018780 PS00659 Glycosyl hydrolases family 5 signature. 216591018781 6 probable transmembrane helices predicted for BCAM0203 by TMHMM2.0 at aa 5-24, 59-81, 88-107, 112-129, 141-163 and 173-195 216591018782 12 probable transmembrane helices predicted for BCAM0204 by TMHMM2.0 at aa 7-29, 33-55, 78-100, 115-137, 146-168, 173-195, 215-234, 254-276, 297-319, 334-356, 363-385 and 390-412 216591018783 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018784 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018785 Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230 216591018786 Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230 216591018787 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 216591018788 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591018789 HMMPfam hit to PF00534, Glycosyl transferases group, score 1.9e-24 216591018790 tyrosine kinase; Provisional; Region: PRK11519 216591018791 Chain length determinant protein; Region: Wzz; pfam02706 216591018792 G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807 216591018793 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 216591018794 PS00030 Eukaryotic putative RNA-binding region RNP-1 signature. 216591018795 2 probable transmembrane helices predicted for BCAM0207 by TMHMM2.0 at aa 23-45 and 440-459 216591018796 HMMPfam hit to PF02706, Chain length determinant protein, score 9.8e-38 216591018797 Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451 216591018798 Low molecular weight phosphatase family; Region: LMWPc; cd00115 216591018799 active site 216591018800 HMMPfam hit to PF01451, Low molecular weight phosphotyrosine protein, score 5.2e-32 216591018801 Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563 216591018802 polysaccharide export protein EpsE; Region: EpsE; TIGR03028 216591018803 SLBB domain; Region: SLBB; pfam10531 216591018804 HMMPfam hit to PF02563, Polysaccharide biosynthesis/export protei, score 1.7e-39 216591018805 CoA-binding domain; Region: CoA_binding_3; pfam13727 216591018806 Bacterial sugar transferase; Region: Bac_transf; pfam02397 216591018807 HMMPfam hit to PF02397, Bacterial sugar transferase, score 2e-29 216591018808 5 probable transmembrane helices predicted for BCAM0210 by TMHMM2.0 at aa 12-29, 39-61, 74-96, 106-125 and 279-298 216591018809 TPR repeat; Region: TPR_11; pfam13414 216591018810 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591018811 binding surface 216591018812 TPR motif; other site 216591018813 TPR repeat; Region: TPR_11; pfam13414 216591018814 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 216591018815 TPR motif; other site 216591018816 binding surface 216591018817 PS00017 ATP/GTP-binding site motif A (P-loop). 216591018818 3 probable transmembrane helices predicted for BCAM0213 by TMHMM2.0 at aa 10-29, 41-63 and 83-102 216591018819 Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532 216591018820 HMMPfam hit to PF01755, Glycosyltransferase family 25 (LPS bi, score 1.2e-05 216591018821 PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145 216591018822 1 probable transmembrane helix predicted for BCAM0215 by TMHMM2.0 at aa 7-29 216591018823 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018824 HMMPfam hit to PF00639, PPIC-type PPIASE domain, score 6.5e-05 216591018825 Helix-turn-helix domain; Region: HTH_37; pfam13744 216591018826 Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446 216591018827 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591018828 dimer interface [polypeptide binding]; other site 216591018829 phosphorylation site [posttranslational modification] 216591018830 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591018831 ATP binding site [chemical binding]; other site 216591018832 Mg2+ binding site [ion binding]; other site 216591018833 G-X-G motif; other site 216591018834 Response regulator receiver domain; Region: Response_reg; pfam00072 216591018835 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591018836 active site 216591018837 phosphorylation site [posttranslational modification] 216591018838 intermolecular recognition site; other site 216591018839 dimerization interface [polypeptide binding]; other site 216591018840 HMMPfam hit to PF01627, Hpt domain, score 2.3e-06 216591018841 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.3e-29 216591018842 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 3.3e-41 216591018843 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.7e-20 216591018844 2 probable transmembrane helices predicted for BCAM0218 by TMHMM2.0 at aa 37-59 and 373-395 216591018845 Haemagglutinin; Region: HIM; pfam05662 216591018846 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591018847 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591018848 trimer interface [polypeptide binding]; other site 216591018849 Haemagglutinin; Region: HIM; pfam05662 216591018850 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591018851 trimer interface [polypeptide binding]; other site 216591018852 YadA-like C-terminal region; Region: YadA; pfam03895 216591018853 HMMPfam hit to PF05662, Haemagglutinin, score 2.9e-05 216591018854 HMMPfam hit to PF05658, Hep_Hag, score 0.00055 216591018855 HMMPfam hit to PF05658, Hep_Hag, score 0.003 216591018856 HMMPfam hit to PF05658, Hep_Hag, score 0.58 216591018857 HMMPfam hit to PF05658, Hep_Hag, score 2.5e-05 216591018858 HMMPfam hit to PF05662, Haemagglutinin, score 3.4e-06 216591018859 HMMPfam hit to PF05658, Hep_Hag, score 1.2 216591018860 HMMPfam hit to PF05658, Hep_Hag, score 0.00046 216591018861 HMMPfam hit to PF05662, Haemagglutinin, score 1.7e-08 216591018862 HMMPfam hit to PF05662, Haemagglutinin, score 7.5e-05 216591018863 HMMPfam hit to PF05662, Haemagglutinin, score 0.00013 216591018864 HMMPfam hit to PF05662, Haemagglutinin, score 7.5e-05 216591018865 HMMPfam hit to PF05662, Haemagglutinin, score 3.5e-06 216591018866 HMMPfam hit to PF05658, Hep_Hag, score 6.8e-05 216591018867 HMMPfam hit to PF05658, Hep_Hag, score 0.0029 216591018868 HMMPfam hit to PF05662, Haemagglutinin, score 2.4e-06 216591018869 HMMPfam hit to PF05658, Hep_Hag, score 0.05 216591018870 HMMPfam hit to PF05658, Hep_Hag, score 0.00062 216591018871 HMMPfam hit to PF05658, Hep_Hag, score 0.055 216591018872 HMMPfam hit to PF05658, Hep_Hag, score 0.012 216591018873 HMMPfam hit to PF05662, Haemagglutinin, score 1.3e-07 216591018874 HMMPfam hit to PF05662, Haemagglutinin, score 0.00013 216591018875 HMMPfam hit to PF05662, Haemagglutinin, score 0.00013 216591018876 HMMPfam hit to PF05662, Haemagglutinin, score 0.00027 216591018877 HMMPfam hit to PF05662, Haemagglutinin, score 0.00013 216591018878 HMMPfam hit to PF05662, Haemagglutinin, score 0.00013 216591018879 HMMPfam hit to PF05662, Haemagglutinin, score 0.00013 216591018880 HMMPfam hit to PF05662, Haemagglutinin, score 1e-06 216591018881 HMMPfam hit to PF05662, Haemagglutinin, score 0.00011 216591018882 HMMPfam hit to PF05662, Haemagglutinin, score 1.3e-06 216591018883 HMMPfam hit to PF05662, Haemagglutinin, score 0.0002 216591018884 HMMPfam hit to PF05662, Haemagglutinin, score 3.4e-05 216591018885 HMMPfam hit to PF05658, Hep_Hag, score 1.9 216591018886 HMMPfam hit to PF05658, Hep_Hag, score 0.0049 216591018887 HMMPfam hit to PF05658, Hep_Hag, score 1.6e-07 216591018888 HMMPfam hit to PF03895, YadA-like C-terminal region, score 4.4e-07 216591018889 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591018890 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 216591018891 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591018892 ligand binding site [chemical binding]; other site 216591018893 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591018894 HMMPfam hit to PF00691, OmpA family, score 1.7e-25 216591018895 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591018896 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591018897 active site 216591018898 phosphorylation site [posttranslational modification] 216591018899 intermolecular recognition site; other site 216591018900 dimerization interface [polypeptide binding]; other site 216591018901 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591018902 DNA binding residues [nucleotide binding] 216591018903 dimerization interface [polypeptide binding]; other site 216591018904 HMMPfam hit to PF00072, Response regulator receiver domain, score 9.2e-12 216591018905 HMMPfam hit to PF08281, Sigma-70, region, score 1.8e-05 216591018906 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 9.9e-18 216591018907 PS00622 Bacterial regulatory proteins, luxR family signature. 216591018908 Predicted helix-turn-helix motif with score 1045.000, SD 2.75 at aa 173-194, sequence LTVNEIADQLSRSKKTISTQKA 216591018909 transcriptional regulator RcsB; Provisional; Region: PRK10840 216591018910 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591018911 active site 216591018912 phosphorylation site [posttranslational modification] 216591018913 intermolecular recognition site; other site 216591018914 dimerization interface [polypeptide binding]; other site 216591018915 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591018916 DNA binding residues [nucleotide binding] 216591018917 dimerization interface [polypeptide binding]; other site 216591018918 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 6.7e-21 216591018919 PS00622 Bacterial regulatory proteins, luxR family signature. 216591018920 Predicted helix-turn-helix motif with score 1195.000, SD 3.26 at aa 169-190, sequence LSVNEIAEKLNRSKKTISTQKS 216591018921 HMMPfam hit to PF00072, Response regulator receiver domain, score 1e-11 216591018922 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591018923 trimer interface [polypeptide binding]; other site 216591018924 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 216591018925 trimer interface [polypeptide binding]; other site 216591018926 YadA-like C-terminal region; Region: YadA; pfam03895 216591018927 HMMPfam hit to PF03895, YadA-like C-terminal region, score 3.6e-07 216591018928 HMMPfam hit to PF05658, Hep_Hag, score 5.1e-06 216591018929 HMMPfam hit to PF05658, Hep_Hag, score 1.4e-05 216591018930 HMMPfam hit to PF05658, Hep_Hag, score 0.0013 216591018931 HMMPfam hit to PF05662, Haemagglutinin, score 2.8e-05 216591018932 HMMPfam hit to PF05658, Hep_Hag, score 0.48 216591018933 HMMPfam hit to PF05658, Hep_Hag, score 0.0026 216591018934 HMMPfam hit to PF05658, Hep_Hag, score 0.44 216591018935 HMMPfam hit to PF05658, Hep_Hag, score 0.26 216591018936 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591018937 trimer interface [polypeptide binding]; other site 216591018938 YadA-like C-terminal region; Region: YadA; pfam03895 216591018939 HMMPfam hit to PF03895, YadA-like C-terminal region, score 4.5e-15 216591018940 HMMPfam hit to PF05662, Haemagglutinin, score 7.6e-07 216591018941 HMMPfam hit to PF05658, Hep_Hag, score 0.0063 216591018942 HMMPfam hit to PF05658, Hep_Hag, score 2.6e-05 216591018943 HMMPfam hit to PF05658, Hep_Hag, score 0.071 216591018944 HMMPfam hit to PF05658, Hep_Hag, score 0.017 216591018945 HMMPfam hit to PF05662, Haemagglutinin, score 9.9e-05 216591018946 PS00583 pfkB family of carbohydrate kinases signature 1. 216591018947 HMMPfam hit to PF05662, Haemagglutinin, score 0.00024 216591018948 HMMPfam hit to PF05658, Hep_Hag, score 0.73 216591018949 HMMPfam hit to PF05658, Hep_Hag, score 0.16 216591018950 HMMPfam hit to PF05658, Hep_Hag, score 0.068 216591018951 Possible gene remnant. Partial similarity to Escherichia coli O6 putative adhesin. UniProt:Q8FCB2 (1778 aa) fasta scores: E()=1e-05, 36.527% id in 167 aa; contains two haemagglutinin motifs 216591018952 HMMPfam hit to PF05662, Haemagglutinin, score 7.4e-07 216591018953 Probable gene remnant. Similar to an internal region of Burkholderia xenovorans (strain LB400) outer membrane protein, putative autotransporter and adhesin UniProt:Q13WU9 (EMBL:CP000270 (810 aa) fasta scores: E()=3e-07, 51.190% id in 84 aa 216591018954 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591018955 dimer interface [polypeptide binding]; other site 216591018956 phosphorylation site [posttranslational modification] 216591018957 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591018958 ATP binding site [chemical binding]; other site 216591018959 Mg2+ binding site [ion binding]; other site 216591018960 G-X-G motif; other site 216591018961 Response regulator receiver domain; Region: Response_reg; pfam00072 216591018962 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591018963 active site 216591018964 phosphorylation site [posttranslational modification] 216591018965 intermolecular recognition site; other site 216591018966 dimerization interface [polypeptide binding]; other site 216591018967 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.8e-31 216591018968 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 5e-40 216591018969 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.2e-23 216591018970 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 216591018971 2 probable transmembrane helices predicted for BCAM0227 by TMHMM2.0 at aa 41-63 and 361-383 216591018972 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591018973 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591018974 DNA binding site [nucleotide binding] 216591018975 HMMPfam hit to PF00486, Transcriptional regulatory protein, C ter, score 6.1e-06 216591018976 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591018977 dimer interface [polypeptide binding]; other site 216591018978 phosphorylation site [posttranslational modification] 216591018979 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591018980 ATP binding site [chemical binding]; other site 216591018981 Mg2+ binding site [ion binding]; other site 216591018982 G-X-G motif; other site 216591018983 2 probable transmembrane helices predicted for BCAM0229 by TMHMM2.0 at aa 4-26 and 207-229 216591018984 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 7e-09 216591018985 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1e-30 216591018986 Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566 216591018987 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591018988 active site 216591018989 phosphorylation site [posttranslational modification] 216591018990 intermolecular recognition site; other site 216591018991 dimerization interface [polypeptide binding]; other site 216591018992 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591018993 DNA binding residues [nucleotide binding] 216591018994 dimerization interface [polypeptide binding]; other site 216591018995 HMMPfam hit to PF00072, Response regulator receiver domain, score 8.3e-28 216591018996 HMMPfam hit to PF08281, Sigma-70, region, score 0.0031 216591018997 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 1.2e-21 216591018998 PS00622 Bacterial regulatory proteins, luxR family signature. 216591018999 Predicted helix-turn-helix motif with score 1411.000, SD 3.99 at aa 166-187, sequence GSNKAIARALGLSPRTVETYRA 216591019000 Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637 216591019001 HMMPfam hit to PF02462, Opacity family porin protein, score 0.00046 216591019002 Cenocepacia Island; BcenGI11 216591019003 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591019004 dimerization interface [polypeptide binding]; other site 216591019005 putative DNA binding site [nucleotide binding]; other site 216591019006 putative Zn2+ binding site [ion binding]; other site 216591019007 HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family, score 0.0026 216591019008 Predicted helix-turn-helix motif with score 1327.000, SD 3.71 at aa 33-54, sequence MPAGQIATLLDVPPSSLSFHLK 216591019009 Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394 216591019010 Low molecular weight phosphatase family; Region: LMWPc; cd00115 216591019011 active site 216591019012 HMMPfam hit to PF01451, Low molecular weight phosphotyrosine protein, score 4.9e-24 216591019013 Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798 216591019014 arsenical-resistance protein; Region: acr3; TIGR00832 216591019015 10 probable transmembrane helices predicted for BCAM0235 by TMHMM2.0 at aa 21-43, 53-75, 96-115, 130-152, 165-184, 189-211, 233-252, 262-284, 297-319 and 324-346 216591019016 HMMPfam hit to PF01758, Sodium Bile acid symporter family, score 2.6e-29 216591019017 arsenical resistance protein ArsH; Region: resist_ArsH; TIGR02690 216591019018 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591019019 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 2.6e-54 216591019020 Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095 216591019021 HMMPfam hit to PF01914, MarC family integral membrane protein, score 2.2e-20 216591019022 5 probable transmembrane helices predicted for BCAM0237A by TMHMM2.0 at aa 10-32, 53-75, 120-142, 151-173 and 193-215 216591019023 Ion transport protein; Region: Ion_trans; pfam00520 216591019024 Ion channel; Region: Ion_trans_2; pfam07885 216591019025 4 probable transmembrane helices predicted for BCAM0238 by TMHMM2.0 at aa 43-65, 107-129, 166-188 and 230-252 216591019026 HMMPfam hit to PF07885, Ion channel, score 2.5e-15 216591019027 HMMPfam hit to PF00520, Ion transport protein, score 2.1e-22 216591019028 H-NS histone family; Region: Histone_HNS; pfam00816 216591019029 Domain in histone-like proteins of HNS family; Region: HNS; smart00528 216591019030 Autoinducer synthetase; Region: Autoind_synth; cl17404 216591019031 HMMPfam hit to PF00765, Autoinducer synthetase, score 5.8e-10 216591019032 1 probable transmembrane helix predicted for BCAM0239a by TMHMM2.0 at aa 122-144 216591019033 PS00949 Autoinducers synthetases family signature. 216591019034 Autoinducer binding domain; Region: Autoind_bind; pfam03472 216591019035 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591019036 DNA binding residues [nucleotide binding] 216591019037 dimerization interface [polypeptide binding]; other site 216591019038 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 3.9e-17 216591019039 Predicted helix-turn-helix motif with score 1269.000, SD 3.51 at aa 215-236, sequence KSSWAIASIVGISPHTVDYHIA 216591019040 PS00017 ATP/GTP-binding site motif A (P-loop). 216591019041 HMMPfam hit to PF03472, Autoinducer binding domain, score 1.8e-10 216591019042 hypothetical protein; Validated; Region: PRK06840 216591019043 Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938 216591019044 active site 216591019045 HMMPfam hit to PF08541, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 3.3e-07 216591019046 HMMPfam hit to PF08545, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 9.4e-06 216591019047 Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938 216591019048 active site 216591019049 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 216591019050 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591019051 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591019052 HMMPfam hit to PF00278, Pyridoxal-dependent decarboxylase, C-, score 1.6e-27 216591019053 HMMPfam hit to PF02784, Pyridoxal-dependent decarboxylase, py, score 1e-38 216591019054 Transposase; Region: HTH_Tnp_1; pfam01527 216591019055 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591019056 HMMPfam hit to PF01527, Transposase, score 1.2e-10 216591019057 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591019058 IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717 216591019059 HMMPfam hit to PF05717, IS66 Orf2 like protein, score 3.2e-62 216591019060 Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007 216591019061 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 216591019062 putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005 216591019063 Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050 216591019064 IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817 216591019065 HMMPfam hit to PF03050, Transposase IS66 family, score 1.1e-99 216591019066 acyl-CoA ligase (AMP-forming), exosortase A-associated; Region: ligase_PEP_1; TIGR03098 216591019067 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591019068 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591019069 acyl-activating enzyme (AAE) consensus motif; other site 216591019070 AMP binding site [chemical binding]; other site 216591019071 active site 216591019072 CoA binding site [chemical binding]; other site 216591019073 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.5e-114 216591019074 PS00455 Putative AMP-binding domain signature. 216591019075 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019076 3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332 216591019077 Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938 216591019078 active site 216591019079 HMMPfam hit to PF08541, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 5.5e-07 216591019080 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019081 Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938 216591019082 active site 216591019083 HMMPfam hit to PF08541, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 0.0011 216591019084 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 216591019085 PS00012 Phosphopantetheine attachment site. 216591019086 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591019087 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 216591019088 active site 216591019089 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 2.9e-18 216591019090 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 0.0042 216591019091 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 3.3e-22 216591019092 BCESM - Burkholderia cepacia epidemic strain marker 216591019093 Transcriptional regulators [Transcription]; Region: FadR; COG2186 216591019094 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591019095 DNA-binding site [nucleotide binding]; DNA binding site 216591019096 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 216591019097 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 5.6e-11 216591019098 HMMPfam hit to PF07729, FCD domain, score 8.3e-27 216591019099 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591019100 non-specific DNA binding site [nucleotide binding]; other site 216591019101 salt bridge; other site 216591019102 sequence-specific DNA binding site [nucleotide binding]; other site 216591019103 HMMPfam hit to PF01381, Helix-turn-helix, score 2e-10 216591019104 Predicted helix-turn-helix motif with score 1344.000, SD 3.76 at aa 26-47, sequence LTQVGLATRANVHPNTISLVER 216591019105 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591019106 non-specific DNA binding site [nucleotide binding]; other site 216591019107 salt bridge; other site 216591019108 sequence-specific DNA binding site [nucleotide binding]; other site 216591019109 HMMPfam hit to PF01381, Helix-turn-helix, score 2.6e-06 216591019110 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591019111 non-specific DNA binding site [nucleotide binding]; other site 216591019112 salt bridge; other site 216591019113 sequence-specific DNA binding site [nucleotide binding]; other site 216591019114 HMMPfam hit to PF01381, Helix-turn-helix, score 2.4e-08 216591019115 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591019116 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 216591019117 TM-ABC transporter signature motif; other site 216591019118 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 3.1e-29 216591019119 6 probable transmembrane helices predicted for BCAM0260 by TMHMM2.0 at aa 5-27, 57-76, 83-102, 132-154, 186-208 and 223-245 216591019120 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019121 ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177 216591019122 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 216591019123 TM-ABC transporter signature motif; other site 216591019124 7 probable transmembrane helices predicted for BCAM0261 by TMHMM2.0 at aa 26-48, 68-90, 100-122, 129-148, 180-202, 231-253 and 303-325 216591019125 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 4e-26 216591019126 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019127 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019128 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019129 urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411 216591019130 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 216591019131 Walker A/P-loop; other site 216591019132 ATP binding site [chemical binding]; other site 216591019133 Q-loop/lid; other site 216591019134 ABC transporter signature motif; other site 216591019135 Walker B; other site 216591019136 D-loop; other site 216591019137 H-loop/switch region; other site 216591019138 HMMPfam hit to PF00005, ABC transporter score 5.2e-32 216591019139 PS00017 ATP/GTP-binding site motif A (P-loop). 216591019140 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 216591019141 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 216591019142 Walker A/P-loop; other site 216591019143 ATP binding site [chemical binding]; other site 216591019144 Q-loop/lid; other site 216591019145 ABC transporter signature motif; other site 216591019146 Walker B; other site 216591019147 D-loop; other site 216591019148 H-loop/switch region; other site 216591019149 HMMPfam hit to PF00005, ABC transporter score 7.7e-47 216591019150 PS00017 ATP/GTP-binding site motif A (P-loop). 216591019151 PS00211 ABC transporters family signature. 216591019152 Periplasmic binding protein; Region: Peripla_BP_6; pfam13458 216591019153 Type I periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF); Region: PBP1_AmiC_like; cd06331 216591019154 ligand binding site [chemical binding]; other site 216591019155 1 probable transmembrane helix predicted for BCAM0264 by TMHMM2.0 at aa 9-31 216591019156 putative amidase; Provisional; Region: PRK06169 216591019157 Amidase; Region: Amidase; pfam01425 216591019158 HMMPfam hit to PF01425, Amidase, score 6.4e-98 216591019159 PS00017 ATP/GTP-binding site motif A (P-loop). 216591019160 PS00571 Amidases signature. 216591019161 Amino acid synthesis; Region: AA_synth; pfam06684 216591019162 HMMPfam hit to PF06684, Protein of unknown function (DUF1185), score 2.5e-25 216591019163 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591019164 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591019165 trimer interface [polypeptide binding]; other site 216591019166 eyelet of channel; other site 216591019167 HMMPfam hit to PF00267, Gram-negative porin, score 0.00058 216591019168 Protein of unknown function (DUF2384); Region: DUF2384; pfam09722 216591019169 M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393 216591019170 M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393 216591019171 active site 216591019172 Zn binding site [ion binding]; other site 216591019173 Zn binding site [ion binding]; other site 216591019174 Protein of unknown function (DUF1778); Region: DUF1778; pfam08681 216591019175 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591019176 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 216591019177 Coenzyme A binding pocket [chemical binding]; other site 216591019178 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.3e-12 216591019179 Probable gene remnant. CDS is truncated at the N-terminus in comparison to similar proteins, for example: similar to Escherichia coli hypothetical protein YhcG UniProt:YHCG_ECOLI (EMBL:U00096) (375 aa) fasta scores: E()=2.8e-65, 62.463% id in 341 aa 216591019180 HMMPfam hit to PF06250, Protein of unknown function (DUF1016), score 1.4e-136 216591019181 CDS contains a frameshift after codon 13. Similar to Burkholderia cenocepacia (strain HI2424) hypothetical protein UniProt:A0B4X6 (EMBL:CP000461 (142 aa) fasta scores: E()=3.2e-17, 48.120% id in 133 aa 216591019182 FRG domain; Region: FRG; pfam08867 216591019183 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591019184 Ligand Binding Site [chemical binding]; other site 216591019185 HMMPfam hit to PF00582, Universal stress protein family, score 2.5e-22 216591019186 Protein of unknown function (DUF1488); Region: DUF1488; pfam07369 216591019187 Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071 216591019188 Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471 216591019189 putative dimer interface [polypeptide binding]; other site 216591019190 HMMPfam hit to PF00011, Hsp20/alpha crystallin family, score 1.6e-23 216591019191 This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142 216591019192 putative FMN binding site [chemical binding]; other site 216591019193 NADPH bind site [chemical binding]; other site 216591019194 Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823 216591019195 BON domain; Region: BON; pfam04972 216591019196 BON domain; Region: BON; pfam04972 216591019197 BON domain; Region: BON; pfam04972 216591019198 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 1.3e-09 216591019199 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 7.8e-12 216591019200 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 0.00021 216591019201 Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659 216591019202 Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792 216591019203 Sulfate transporter family; Region: Sulfate_transp; pfam00916 216591019204 Sulfate transporter family; Region: Sulfate_transp; pfam00916 216591019205 Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042 216591019206 HMMPfam hit to PF01740, STAS domain, score 1.1e-14 216591019207 HMMPfam hit to PF00916, Sulfate transporter family, score 3.1e-52 216591019208 11 probable transmembrane helices predicted for BCAM0281 by TMHMM2.0 at aa 25-47, 51-73, 78-100, 110-132, 145-167, 182-204, 211-230, 250-272, 332-354, 359-381 and 388-410 216591019209 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019210 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019211 Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611 216591019212 HMMPfam hit to PF03641, Possible lysine decarboxylase, score 2.7e-48 216591019213 Cytochrome c; Region: Cytochrom_C; cl11414 216591019214 PS00190 Cytochrome c family heme-binding site signature. 216591019215 Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514 216591019216 FMN binding site [chemical binding]; other site 216591019217 dimer interface [polypeptide binding]; other site 216591019218 Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514 216591019219 Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064 216591019220 Cinnamyl alcohol dehydrogenases (CAD); Region: CAD2; cd08298 216591019221 putative NAD(P) binding site [chemical binding]; other site 216591019222 putative substrate binding site [chemical binding]; other site 216591019223 catalytic Zn binding site [ion binding]; other site 216591019224 structural Zn binding site [ion binding]; other site 216591019225 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 5.1e-45 216591019226 fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161 216591019227 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 216591019228 ligand binding site [chemical binding]; other site 216591019229 flexible hinge region; other site 216591019230 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 216591019231 putative switch regulator; other site 216591019232 non-specific DNA interactions [nucleotide binding]; other site 216591019233 DNA binding site [nucleotide binding] 216591019234 sequence specific DNA binding site [nucleotide binding]; other site 216591019235 putative cAMP binding site [chemical binding]; other site 216591019236 HMMPfam hit to PF00325, Bacterial regulatory proteins, crp famil, score 1.3e-11 216591019237 Predicted helix-turn-helix motif with score 1607.000, SD 4.66 at aa 210-231, sequence MTRDEIGEYLGMKLETVSRMLS 216591019238 HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 1.7e-17 216591019239 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591019240 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591019241 active site 216591019242 phosphorylation site [posttranslational modification] 216591019243 intermolecular recognition site; other site 216591019244 dimerization interface [polypeptide binding]; other site 216591019245 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591019246 DNA binding residues [nucleotide binding] 216591019247 dimerization interface [polypeptide binding]; other site 216591019248 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 9.8e-17 216591019249 Predicted helix-turn-helix motif with score 1738.000, SD 5.11 at aa 164-185, sequence ESISEIAQALCVSVKTVSTYKT 216591019250 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.1e-34 216591019251 CHASE domain; Region: CHASE; cl01369 216591019252 CHASE domain; Region: CHASE; cl01369 216591019253 PAS domain S-box; Region: sensory_box; TIGR00229 216591019254 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591019255 putative active site [active] 216591019256 heme pocket [chemical binding]; other site 216591019257 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585 216591019258 Histidine kinase; Region: HisKA_3; pfam07730 216591019259 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591019260 ATP binding site [chemical binding]; other site 216591019261 Mg2+ binding site [ion binding]; other site 216591019262 G-X-G motif; other site 216591019263 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5.7e-20 216591019264 HMMPfam hit to PF07730, Histidine kinase, score 1.1e-16 216591019265 HMMPfam hit to PF08448, PAS fold, score 5.6e-11 216591019266 HMMPfam hit to PF00989, PAS fold, score 5e-13 216591019267 1 probable transmembrane helix predicted for BCAM0289 by TMHMM2.0 at aa 21-43 216591019268 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591019269 Ligand Binding Site [chemical binding]; other site 216591019270 HMMPfam hit to PF00582, Universal stress protein family, score 1.5e-19 216591019271 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591019272 Ligand Binding Site [chemical binding]; other site 216591019273 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591019274 Ligand Binding Site [chemical binding]; other site 216591019275 HMMPfam hit to PF00582, Universal stress protein family, score 6.5e-14 216591019276 PS00616 Histidine acid phosphatases phosphohistidine signature. 216591019277 HMMPfam hit to PF00582, Universal stress protein family, score 3.9e-09 216591019278 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591019279 Ligand Binding Site [chemical binding]; other site 216591019280 HMMPfam hit to PF00582, Universal stress protein family, score 1.9e-28 216591019281 Acetate kinase [Energy production and conversion]; Region: ackA; COG0282 216591019282 HMMPfam hit to PF00871, Acetokinase family, score 3.3e-101 216591019283 PS01075 Acetate and butyrate kinases family signature 1. 216591019284 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591019285 Ligand Binding Site [chemical binding]; other site 216591019286 HMMPfam hit to PF00582, Universal stress protein family, score 1.6e-13 216591019287 HMMPfam hit to PF00582, Universal stress protein family, score 3.7e-08 216591019288 acetoacetyl-CoA reductase; Region: AcAcCoA_reduct; TIGR01829 216591019289 beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333 216591019290 NAD(P) binding site [chemical binding]; other site 216591019291 homotetramer interface [polypeptide binding]; other site 216591019292 homodimer interface [polypeptide binding]; other site 216591019293 active site 216591019294 HMMPfam hit to PF00106, short chain dehydrogenase, score 3e-37 216591019295 PS00061 Short-chain dehydrogenases/reductases family signature. 216591019296 Poly-beta-hydroxybutyrate polymerase N terminal; Region: PHBC_N; pfam12551 216591019297 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167 216591019298 Poly(3-hydroxyalkanoate) synthetase [Lipid metabolism]; Region: PhaC; COG3243 216591019299 HMMPfam hit to PF07167, Poly-beta-hydroxybutyrate polymerase (P, score 5.7e-58 216591019300 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 0.00051 216591019301 Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212 216591019302 HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 4.7e-23 216591019303 formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH2; cd08286 216591019304 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 216591019305 catalytic Zn binding site [ion binding]; other site 216591019306 structural Zn binding site [ion binding]; other site 216591019307 NAD(P) binding site [chemical binding]; other site 216591019308 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 2.8e-46 216591019309 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591019310 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 8e-32 216591019311 Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236 216591019312 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 216591019313 Beta-Casp domain; Region: Beta-Casp; smart01027 216591019314 RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521 216591019315 HMMPfam hit to PF07521, RNA-metabolising metallo-beta-lactamase, score 1.4e-08 216591019316 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 3.2e-21 216591019317 Protein of unknown function (DUF2964); Region: DUF2964; pfam11177 216591019318 2 probable transmembrane helices predicted for BCAM0301 by TMHMM2.0 at aa 9-31 and 35-54 216591019319 YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061 216591019320 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 216591019321 ABC-2 type transporter; Region: ABC2_membrane; pfam01061 216591019322 5 probable transmembrane helices predicted for BCAM0302 by TMHMM2.0 at aa 23-40, 226-248, 258-280, 287-306 and 344-366 216591019323 HMMPfam hit to PF01061, ABC-2 type transporter score 3.4e-28 216591019324 PS00890 ABC-2 type transport system integral membrane proteins signature. 216591019325 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 216591019326 ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123 216591019327 Walker A/P-loop; other site 216591019328 ATP binding site [chemical binding]; other site 216591019329 Q-loop/lid; other site 216591019330 ABC transporter signature motif; other site 216591019331 Walker B; other site 216591019332 D-loop; other site 216591019333 H-loop/switch region; other site 216591019334 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 216591019335 Walker A/P-loop; other site 216591019336 ATP binding site [chemical binding]; other site 216591019337 Q-loop/lid; other site 216591019338 ABC transporter signature motif; other site 216591019339 Walker B; other site 216591019340 D-loop; other site 216591019341 H-loop/switch region; other site 216591019342 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 216591019343 ABC-2 type transporter; Region: ABC2_membrane; pfam01061 216591019344 5 probable transmembrane helices predicted for BCAM0303 by TMHMM2.0 at aa 740-762, 783-805, 820-842, 847-869 and 910-929 216591019345 HMMPfam hit to PF01061, ABC-2 type transporter score 7.4e-10 216591019346 HMMPfam hit to PF00005, ABC transporter score 4.6e-53 216591019347 PS00017 ATP/GTP-binding site motif A (P-loop). 216591019348 HMMPfam hit to PF00005, ABC transporter score 6.1e-44 216591019349 PS00211 ABC transporters family signature. 216591019350 PS00017 ATP/GTP-binding site motif A (P-loop). 216591019351 putative efflux pump membrane fusion protein; Provisional; Region: PRK03598 216591019352 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591019353 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591019354 HMMPfam hit to PF00529, HlyD family secretion protein, score 3.1e-24 216591019355 1 probable transmembrane helix predicted for BCAM0304 by TMHMM2.0 at aa 7-29 216591019356 Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538 216591019357 HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.2e-38 216591019358 HMMPfam hit to PF02321, Outer membrane efflux protein, score 7e-32 216591019359 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019360 Protein of unknown function (DUF2964); Region: DUF2964; pfam11177 216591019361 2 probable transmembrane helices predicted for BCAM0306 by TMHMM2.0 at aa 9-31 and 35-57 216591019362 Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823 216591019363 BON domain; Region: BON; pfam04972 216591019364 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 5.1e-10 216591019365 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 2.6e-12 216591019366 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 2.7e-09 216591019367 ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241 216591019368 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591019369 Walker A motif; other site 216591019370 ATP binding site [chemical binding]; other site 216591019371 Walker B motif; other site 216591019372 arginine finger; other site 216591019373 Peptidase family M41; Region: Peptidase_M41; pfam01434 216591019374 3 probable transmembrane helices predicted for BCAM0309 by TMHMM2.0 at aa 7-26, 116-138 and 226-248 216591019375 HMMPfam hit to PF06480, FtsH Extracellular, score 4.1e-25 216591019376 HMMPfam hit to PF00004, ATPase family associated with various c, score 1.9e-93 216591019377 HMMPfam hit to PF07728, ATPase family associated with various c, score 8.8e-05 216591019378 PS00017 ATP/GTP-binding site motif A (P-loop). 216591019379 PS00674 AAA-protein family signature. 216591019380 PS01034 Glycosyl hydrolases family 16 active sites. 216591019381 HMMPfam hit to PF01434, Peptidase family M41, score 5.4e-96 216591019382 ribonucleotide reductase-like protein; Provisional; Region: PRK06948 216591019383 Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317 216591019384 Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888 216591019385 active site 216591019386 dimer interface [polypeptide binding]; other site 216591019387 effector binding site; other site 216591019388 HMMPfam hit to PF02867, Ribonucleotide reductase, barrel doma, score 5.3e-14 216591019389 PS00237 G-protein coupled receptors signature. 216591019390 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105 216591019391 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164 216591019392 putative substrate binding site [chemical binding]; other site 216591019393 putative ATP binding site [chemical binding]; other site 216591019394 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 6.8e-50 216591019395 PS00583 pfkB family of carbohydrate kinases signature 1. 216591019396 PS00584 pfkB family of carbohydrate kinases signature 2. 216591019397 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019398 Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918 216591019399 putative active site [active] 216591019400 putative metal binding site [ion binding]; other site 216591019401 HMMPfam hit to PF01522, Polysaccharide deacetylase, score 1.8e-23 216591019402 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 216591019403 Putative glycosyl hydrolase domain; Region: DUF4015; pfam13200 216591019404 Lecithin retinol acyltransferase; Region: LRAT; pfam04970 216591019405 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019406 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591019407 SNARE associated Golgi protein; Region: SNARE_assoc; cl00429 216591019408 5 probable transmembrane helices predicted for BCAM0317 by TMHMM2.0 at aa 5-27, 40-62, 91-113, 123-145 and 158-180 216591019409 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512 216591019410 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 216591019411 Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814 216591019412 6 probable transmembrane helices predicted for BCAM0318 by TMHMM2.0 at aa 22-44, 51-73, 83-105, 245-263, 273-295 and 575-597 216591019413 HMMPfam hit to PF00122, E1-E2 ATPase, score 1e-39 216591019414 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 6.7e-27 216591019415 PS00154 E1-E2 ATPases phosphorylation site. 216591019416 HMMPfam hit to PF01814, Hemerythrin HHE cation binding domain, score 0.0059 216591019417 HMMPfam hit to PF01814, Hemerythrin HHE cation binding domain, score 0.00046 216591019418 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591019419 Ligand Binding Site [chemical binding]; other site 216591019420 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591019421 Ligand Binding Site [chemical binding]; other site 216591019422 HMMPfam hit to PF00582, Universal stress protein family, score 1.9e-13 216591019423 HMMPfam hit to PF00582, Universal stress protein family, score 2.5e-16 216591019424 Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038 216591019425 HMMPfam hit to PF01292, Cytochrome b561 family, score 5.9e-28 216591019426 4 probable transmembrane helices predicted for BCAM0320 by TMHMM2.0 at aa 2-21, 26-45, 73-90 and 127-149 216591019427 Cytochrome b562; Region: Cytochrom_B562; pfam07361 216591019428 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591019429 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591019430 active site 216591019431 phosphorylation site [posttranslational modification] 216591019432 intermolecular recognition site; other site 216591019433 dimerization interface [polypeptide binding]; other site 216591019434 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591019435 DNA binding site [nucleotide binding] 216591019436 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.5e-33 216591019437 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1e-19 216591019438 sensor protein QseC; Provisional; Region: PRK10337 216591019439 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591019440 ATP binding site [chemical binding]; other site 216591019441 Mg2+ binding site [ion binding]; other site 216591019442 G-X-G motif; other site 216591019443 HMMPfam hit to PF00672, HAMP domain, score 2.5e-07 216591019444 1 probable transmembrane helix predicted for BCAM0323 by TMHMM2.0 at aa 162-184 216591019445 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 4.5e-13 216591019446 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.7e-33 216591019447 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591019448 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591019449 catalytic residue [active] 216591019450 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 2.3e-16 216591019451 3 probable transmembrane helices predicted for BCAM0325 by TMHMM2.0 at aa 21-43, 58-80 and 93-115 216591019452 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019453 Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501 216591019454 HMMPfam hit to PF05101, Type IV secretory pathway, VirB3-like protei, score 5.6e-19 216591019455 2 probable transmembrane helices predicted for BCAM0326 by TMHMM2.0 at aa 21-40 and 44-66 216591019456 type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929 216591019457 CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135 216591019458 HMMPfam hit to PF03135, CagE, TrbE, VirB family, component of, score 5.9e-55 216591019459 PS00017 ATP/GTP-binding site motif A (P-loop). 216591019460 TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; pfam04610 216591019461 7 probable transmembrane helices predicted for BCAM0328 by TMHMM2.0 at aa 26-48, 61-83, 167-189, 196-218, 228-250, 280-302 and 306-328 216591019462 HMMPfam hit to PF04610, TrbL/VirB6 plasmid conjugal transfer protein, score 2e-21 216591019463 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019464 Type IV secretion system proteins; Region: T4SS; pfam07996 216591019465 P-type DNA transfer protein VirB5; Region: VirB5; TIGR02791 216591019466 HMMPfam hit to PF07996, Type IV secretion system proteins, score 2.1e-50 216591019467 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019468 VirB8 protein; Region: VirB8; pfam04335 216591019469 1 probable transmembrane helix predicted for BCAM0331 by TMHMM2.0 at aa 31-53 216591019470 HMMPfam hit to PF04335, VirB8 protein, score 7.8e-30 216591019471 VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423 216591019472 VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911 216591019473 VirB7 interaction site; other site 216591019474 HMMPfam hit to PF03524, Conjugal transfer protein, score 2e-57 216591019475 Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743 216591019476 1 probable transmembrane helix predicted for BCAM0333 by TMHMM2.0 at aa 50-72 216591019477 HMMPfam hit to PF03743, Bacterial conjugation TrbI-like protein, score 2.9e-65 216591019478 PS00307 Legume lectins beta-chain signature. 216591019479 P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788 216591019480 Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130 216591019481 Walker A motif; other site 216591019482 hexamer interface [polypeptide binding]; other site 216591019483 ATP binding site [chemical binding]; other site 216591019484 Walker B motif; other site 216591019485 HMMPfam hit to PF00437, Type II/IV secretion system protein, score 1.4e-62 216591019486 PS00017 ATP/GTP-binding site motif A (P-loop). 216591019487 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591019488 Similar to Xanthomonas axonopodis (pv. citri) VirD4 protein UniProt:Q8PJB2 (557 aa) fasta scores: E()=1.6e-91, 45.611% id in 581 aa; homology does not extend to C terminus; frameshift after codon 114; Possibly not pseudogene, but begins at codon 115. However, this would seem to be missing full N-terminus, so more likely to be a pseudogene 216591019489 HMMPfam hit to PF02534, TraG/TraD family, score 1.6e-110 216591019490 Primase C terminal 2 (PriCT-2); Region: PriCT_2; pfam08707 216591019491 Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718 216591019492 active site 216591019493 metal binding site [ion binding]; metal-binding site 216591019494 type IV secretion system T-DNA border endonuclease VirD2; Provisional; Region: PRK13863 216591019495 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 216591019496 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591019497 HMMPfam hit to PF02525, Flavodoxin-like fold, score 2.2e-31 216591019498 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591019499 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591019500 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_6; cd08475 216591019501 putative effector binding pocket; other site 216591019502 putative dimerization interface [polypeptide binding]; other site 216591019503 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.9e-17 216591019504 Predicted helix-turn-helix motif with score 1497.000, SD 4.29 at aa 18-39, sequence SSFAQAAEKLHITRSAVGKSIA 216591019505 PS00044 Bacterial regulatory proteins, lysR family signature. 216591019506 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.7e-45 216591019507 TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966 216591019508 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591019509 catalytic residues [active] 216591019510 HMMPfam hit to PF08534, Redoxin, score 7.8e-10 216591019511 PS00194 Thioredoxin family active site. 216591019512 4 probable transmembrane helices predicted for BCAM0343 by TMHMM2.0 at aa 6-28, 41-63, 73-95 and 108-130 216591019513 Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604 216591019514 PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881 216591019515 oligomeric interface; other site 216591019516 putative active site [active] 216591019517 homodimer interface [polypeptide binding]; other site 216591019518 HMMPfam hit to PF01850, PIN domain, score 6.7e-16 216591019519 SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500 216591019520 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591019521 S-adenosylmethionine binding site [chemical binding]; other site 216591019522 HMMPfam hit to PF08241, Methyltransferase domain, score 4.4e-32 216591019523 HMMPfam hit to PF08242, Methyltransferase domain, score 9.5e-21 216591019524 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591019525 non-specific DNA binding site [nucleotide binding]; other site 216591019526 salt bridge; other site 216591019527 sequence-specific DNA binding site [nucleotide binding]; other site 216591019528 Predicted helix-turn-helix motif with score 1028.000, SD 2.69 at aa 20-41, sequence MNQTEFAAAGGVQQHAQVNYEK 216591019529 Contains frameshift mutations after codons 15, 74 and 126 216591019530 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 8.1e-07 216591019531 ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204 216591019532 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591019533 Walker A/P-loop; other site 216591019534 ATP binding site [chemical binding]; other site 216591019535 Q-loop/lid; other site 216591019536 ABC transporter signature motif; other site 216591019537 Walker B; other site 216591019538 D-loop; other site 216591019539 H-loop/switch region; other site 216591019540 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 5.7e-06 216591019541 5 probable transmembrane helices predicted for BCAM0355 by TMHMM2.0 at aa 40-62, 72-94, 149-171, 181-200 and 263-285 216591019542 PS00037 Myb DNA-binding domain repeat signature 1. 216591019543 HMMPfam hit to PF00005, ABC transporter score 1.2e-52 216591019544 PS00017 ATP/GTP-binding site motif A (P-loop). 216591019545 PS00211 ABC transporters family signature. 216591019546 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591019547 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 216591019548 active site 216591019549 catalytic tetrad [active] 216591019550 HMMPfam hit to PF00248, Aldo/keto reductase family, score 1.5e-68 216591019551 PS00062 Aldo/keto reductase family signature 2. 216591019552 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591019553 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591019554 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591019555 putative effector binding pocket; other site 216591019556 dimerization interface [polypeptide binding]; other site 216591019557 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.3e-16 216591019558 Predicted helix-turn-helix motif with score 1336.000, SD 3.74 at aa 16-37, sequence GGLAAAGREVGLSPATVSERLT 216591019559 PS00044 Bacterial regulatory proteins, lysR family signature. 216591019560 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.2e-45 216591019561 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591019562 dimerization interface [polypeptide binding]; other site 216591019563 putative DNA binding site [nucleotide binding]; other site 216591019564 putative Zn2+ binding site [ion binding]; other site 216591019565 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 216591019566 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591019567 catalytic residue [active] 216591019568 HMMPfam hit to PF00282, Pyridoxal-dependent decarboxylase conse, score 1.4e-14 216591019569 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019570 PS00107 Protein kinases ATP-binding region signature. 216591019571 PS00018 EF-hand calcium-binding domain. 216591019572 putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791 216591019573 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591019574 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591019575 dimerization interface [polypeptide binding]; other site 216591019576 HMMPfam hit to PF03466, LysR substrate binding domain, score 4e-34 216591019577 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.4e-21 216591019578 PS00044 Bacterial regulatory proteins, lysR family signature. 216591019579 Predicted helix-turn-helix motif with score 1718.000, SD 5.04 at aa 16-37, sequence RTIRGAARALGVTQPAVSGIVR 216591019580 allantoate amidohydrolase; Reviewed; Region: PRK12892 216591019581 M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884 216591019582 active site 216591019583 metal binding site [ion binding]; metal-binding site 216591019584 dimer interface [polypeptide binding]; other site 216591019585 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 2.4e-36 216591019586 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 0.0022 216591019587 Cupin domain; Region: Cupin_2; cl17218 216591019588 HMMPfam hit to PF00190, Cupin, score 0.0019 216591019589 HMMPfam hit to PF07883, Cupin domain, score 2.5e-19 216591019590 Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537 216591019591 Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971 216591019592 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019593 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019594 HMMPfam hit to PF07971, Glycosyl hydrolase family, score 6.2e-153 216591019595 Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537 216591019596 Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971 216591019597 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019598 HMMPfam hit to PF07971, Glycosyl hydrolase family, score 6.3e-161 216591019599 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231 216591019600 classical (c) SDRs; Region: SDR_c; cd05233 216591019601 NAD(P) binding site [chemical binding]; other site 216591019602 active site 216591019603 HMMPfam hit to PF00106, short chain dehydrogenase, score 3e-16 216591019604 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 2.6e-05 216591019605 5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346 216591019606 HMMPfam hit to PF01975, Survival protein SurE, score 1e-66 216591019607 Predicted membrane protein [Function unknown]; Region: COG4541 216591019608 3 probable transmembrane helices predicted for BCAM0367 by TMHMM2.0 at aa 10-32, 41-63 and 78-100 216591019609 HMMPfam hit to PF05437, Branched-chain amino acid transport protein, score 2.2e-25 216591019610 Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296 216591019611 5 probable transmembrane helices predicted for BCAM0368 by TMHMM2.0 at aa 24-46, 70-92, 146-168, 178-196 and 217-239 216591019612 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019613 HMMPfam hit to PF03591, AzlC protein, score 6.2e-53 216591019614 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591019615 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591019616 putative DNA binding site [nucleotide binding]; other site 216591019617 putative Zn2+ binding site [ion binding]; other site 216591019618 AsnC family; Region: AsnC_trans_reg; pfam01037 216591019619 HMMPfam hit to PF01037, AsnC family, score 2.1e-27 216591019620 1 probable transmembrane helix predicted for BCAM0370 by TMHMM2.0 at aa 13-35 216591019621 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019622 hypothetical protein; Provisional; Region: PRK11470 216591019623 HMMPfam hit to PF06520, Protein of unknown function (DUF1105), score 5e-46 216591019624 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591019625 HMMPfam hit to PF01810, LysE type translocator, score 6.9e-32 216591019626 5 probable transmembrane helices predicted for BCAM0372 by TMHMM2.0 at aa 7-29, 39-58, 65-87, 146-168 and 188-207 216591019627 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019628 PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768 216591019629 Uncharacterized protein conserved in bacteria (DUF2322); Region: DUF2322; pfam10084 216591019630 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591019631 putative substrate translocation pore; other site 216591019632 14 probable transmembrane helices predicted for BCAM0375 by TMHMM2.0 at aa 23-45, 60-82, 89-111, 115-137, 150-172, 177-199, 212-229, 239-256, 280-302, 312-334, 341-363, 378-400, 413-432 and 442-461 216591019633 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.2e-48 216591019634 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019635 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853 216591019636 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 216591019637 catalytic residues [active] 216591019638 Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894 216591019639 HMMPfam hit to PF01894, Uncharacterised protein family UPF0047, score 3.6e-54 216591019640 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591019641 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591019642 dimer interface [polypeptide binding]; other site 216591019643 phosphorylation site [posttranslational modification] 216591019644 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591019645 ATP binding site [chemical binding]; other site 216591019646 Mg2+ binding site [ion binding]; other site 216591019647 G-X-G motif; other site 216591019648 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591019649 Response regulator receiver domain; Region: Response_reg; pfam00072 216591019650 active site 216591019651 phosphorylation site [posttranslational modification] 216591019652 intermolecular recognition site; other site 216591019653 dimerization interface [polypeptide binding]; other site 216591019654 HMMPfam hit to PF00072, Response regulator receiver domain, score 1e-16 216591019655 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 1.1e-34 216591019656 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.3e-12 216591019657 2 probable transmembrane helices predicted for BCAM0379 by TMHMM2.0 at aa 13-35 and 182-204 216591019658 Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199 216591019659 HMMPfam hit to PF00174, Oxidoreductase molybdopterin binding d, score 6.5e-07 216591019660 PS00430 TonB-dependent receptor proteins signature 1. 216591019661 1 probable transmembrane helix predicted for BCAM0380 by TMHMM2.0 at aa 7-29 216591019662 BetR domain; Region: BetR; pfam08667 216591019663 FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784 216591019664 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591019665 active site 216591019666 phosphorylation site [posttranslational modification] 216591019667 intermolecular recognition site; other site 216591019668 HMMPfam hit to PF00072, Response regulator receiver domain, score 0.00089 216591019669 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 216591019670 Sel1-like repeats; Region: SEL1; smart00671 216591019671 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019672 HMMPfam hit to PF08238, Sel1 repeat, score 1.1e-09 216591019673 HMMPfam hit to PF08238, Sel1 repeat, score 0.018 216591019674 Protein of unknown function (DUF3897); Region: DUF3897; cl17494 216591019675 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019676 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019677 1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism]; Region: Acd; COG2515 216591019678 Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449 216591019679 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591019680 catalytic residue [active] 216591019681 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 2.1e-06 216591019682 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591019683 Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412 216591019684 putative DNA binding site [nucleotide binding]; other site 216591019685 putative Zn2+ binding site [ion binding]; other site 216591019686 AsnC family; Region: AsnC_trans_reg; pfam01037 216591019687 HMMPfam hit to PF01037, AsnC family, score 1.8e-22 216591019688 PS00190 Cytochrome c family heme-binding site signature. 216591019689 pyruvate dehydrogenase; Provisional; Region: PRK09124 216591019690 Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039 216591019691 PYR/PP interface [polypeptide binding]; other site 216591019692 tetramer interface [polypeptide binding]; other site 216591019693 dimer interface [polypeptide binding]; other site 216591019694 TPP binding site [chemical binding]; other site 216591019695 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591019696 Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014 216591019697 TPP-binding site [chemical binding]; other site 216591019698 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 2.3e-61 216591019699 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591019700 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 1.7e-22 216591019701 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 2.6e-50 216591019702 PS00187 Thiamine pyrophosphate enzymes signature. 216591019703 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591019704 HMMPfam hit to PF08241, Methyltransferase domain, score 3e-08 216591019705 HMMPfam hit to PF08242, Methyltransferase domain, score 2e-07 216591019706 Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785 216591019707 Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016 216591019708 active site 216591019709 dimer interface [polypeptide binding]; other site 216591019710 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019711 HMMPfam hit to PF00245, Alkaline phosphatase, score 4.6e-68 216591019712 Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016 216591019713 Alkaline phosphatase homologues; Region: alkPPc; smart00098 216591019714 active site 216591019715 dimer interface [polypeptide binding]; other site 216591019716 1 probable transmembrane helix predicted for BCAM0390 by TMHMM2.0 at aa 7-24 216591019717 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019718 HMMPfam hit to PF00245, Alkaline phosphatase, score 3.5e-59 216591019719 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 216591019720 HMMPfam hit to PF01757, Acyltransferase family, score 2.3e-24 216591019721 10 probable transmembrane helices predicted for BCAM0392 by TMHMM2.0 at aa 12-31, 46-68, 95-117, 137-159, 184-202, 207-229, 238-260, 265-284, 304-323 and 333-355 216591019722 Beta-lactamase class D [Defense mechanisms]; Region: COG2602 216591019723 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 4.1e-51 216591019724 PS00017 ATP/GTP-binding site motif A (P-loop). 216591019725 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591019726 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591019727 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591019728 dimerization interface [polypeptide binding]; other site 216591019729 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-21 216591019730 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.3e-21 216591019731 PS00044 Bacterial regulatory proteins, lysR family signature. 216591019732 Predicted helix-turn-helix motif with score 1625.000, SD 4.72 at aa 19-40, sequence GNMTRAAEAVNRSQSAVSMQIK 216591019733 Protein of unknown function (DUF3422); Region: DUF3422; pfam11902 216591019734 DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242 216591019735 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591019736 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591019737 dimerization interface [polypeptide binding]; other site 216591019738 HMMPfam hit to PF03466, LysR substrate binding domain, score 8.1e-48 216591019739 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.7e-25 216591019740 PS00044 Bacterial regulatory proteins, lysR family signature. 216591019741 Predicted helix-turn-helix motif with score 1958.000, SD 5.86 at aa 16-37, sequence RSFTRAAAALHVSQPALSQQIR 216591019742 Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884 216591019743 active site clefts [active] 216591019744 zinc binding site [ion binding]; other site 216591019745 dimer interface [polypeptide binding]; other site 216591019746 HMMPfam hit to PF00484, Carbonic anhydrase, score 5.9e-86 216591019747 PS00704 Prokaryotic-type carbonic anhydrases signature 1. 216591019748 PS00705 Prokaryotic-type carbonic anhydrases signature 2. 216591019749 cyanate hydratase; Validated; Region: PRK02866 216591019750 Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate. It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559 216591019751 oligomer interface [polypeptide binding]; other site 216591019752 active site 216591019753 HMMPfam hit to PF02560, Cyanate lyase C-terminal domain, score 9.2e-54 216591019754 Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285 216591019755 nucleoside/Zn binding site; other site 216591019756 dimer interface [polypeptide binding]; other site 216591019757 catalytic motif [active] 216591019758 HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 2.1e-20 216591019759 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 216591019760 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.1e-10 216591019761 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591019762 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591019763 TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440 216591019764 putative dimerization interface [polypeptide binding]; other site 216591019765 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.7e-47 216591019766 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.7e-17 216591019767 PS00044 Bacterial regulatory proteins, lysR family signature. 216591019768 Predicted helix-turn-helix motif with score 1631.000, SD 4.74 at aa 18-39, sequence GSFRQAADTLHVTQTAITQRLR 216591019769 Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106 216591019770 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591019771 S-adenosylmethionine binding site [chemical binding]; other site 216591019772 HMMPfam hit to PF08241, Methyltransferase domain, score 5.3e-18 216591019773 HMMPfam hit to PF08242, Methyltransferase domain, score 4.9e-19 216591019774 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 216591019775 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591019776 Coenzyme A binding pocket [chemical binding]; other site 216591019777 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 9.9e-21 216591019778 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591019779 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591019780 trimer interface [polypeptide binding]; other site 216591019781 eyelet of channel; other site 216591019782 HMMPfam hit to PF00267, Gram-negative porin, score 1.8e-07 216591019783 PS00572 Glycosyl hydrolases family 1 active site. 216591019784 phospholipase C, phosphocholine-specific, Pseudomonas-type; Region: PC_PLC; TIGR03396 216591019785 Phosphoesterase family; Region: Phosphoesterase; pfam04185 216591019786 Domain of unknown function (DUF756); Region: DUF756; pfam05506 216591019787 Domain of unknown function (DUF756); Region: DUF756; pfam05506 216591019788 HMMPfam hit to PF05506, Domain of unknown function (DUF756), score 1.6e-12 216591019789 HMMPfam hit to PF05506, Domain of unknown function (DUF756), score 1.2e-16 216591019790 HMMPfam hit to PF04185, Phosphoesterase family, score 2.7e-130 216591019791 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019792 Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560 216591019793 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591019794 motif II; other site 216591019795 choline ABC transporter, periplasmic binding protein; Region: ABC_choline_bnd; TIGR03414 216591019796 ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113 216591019797 HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 2.3e-63 216591019798 MgtC family; Region: MgtC; pfam02308 216591019799 HMMPfam hit to PF02308, MgtC family, score 1.7e-51 216591019800 3 probable transmembrane helices predicted for BCAM0411 by TMHMM2.0 at aa 34-56, 71-89 and 102-133 216591019801 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 216591019802 helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420 216591019803 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 216591019804 HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 4.3e-13 216591019805 HMMPfam hit to PF08279, HTH domain, score 4.4e-05 216591019806 PS00894 Bacterial regulatory proteins, deoR family signature. 216591019807 Predicted helix-turn-helix motif with score 1095.000, SD 2.92 at aa 20-41, sequence VSTDRIMAELNVSRETVRRDLV 216591019808 HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 9.1e-32 216591019809 N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005 216591019810 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 5.7e-14 216591019811 Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087 216591019812 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591019813 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591019814 Arabidopsis betaine aldehyde dehydrogenase 1 and 2, ALDH family 10A8 and 10A9-like; Region: ALDH_F10_BADH; cd07110 216591019815 NAD(P) binding site [chemical binding]; other site 216591019816 catalytic residues [active] 216591019817 catalytic residues [active] 216591019818 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 2.4e-176 216591019819 PS00070 Aldehyde dehydrogenases cysteine active site. 216591019820 Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592 216591019821 agmatinase; Region: agmatinase; TIGR01230 216591019822 oligomer interface [polypeptide binding]; other site 216591019823 putative active site [active] 216591019824 Mn binding site [ion binding]; other site 216591019825 HMMPfam hit to PF00491, Arginase family, score 1.5e-67 216591019826 PS01053 Arginase family signature 3. 216591019827 PS00148 Arginase family signature 2. 216591019828 PS00147 Arginase family signature 1. 216591019829 helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421 216591019830 DNA binding residues [nucleotide binding] 216591019831 dimerization interface [polypeptide binding]; other site 216591019832 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 0.00016 216591019833 Protein of unknown function (DUF861); Region: Cupin_3; cl17594 216591019834 HMMPfam hit to PF05899, Protein of unknown function (DUF861), score 1.3e-05 216591019835 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591019836 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591019837 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 4.3e-60 216591019838 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591019839 12 probable transmembrane helices predicted for BCAM0420 by TMHMM2.0 at aa 16-38, 53-75, 82-104, 109-131, 138-160, 165-187, 210-232, 247-269, 276-293, 297-319, 332-354 and 358-380 216591019840 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019841 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019842 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591019843 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591019844 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591019845 dimerization interface [polypeptide binding]; other site 216591019846 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.5e-13 216591019847 Predicted helix-turn-helix motif with score 1076.000, SD 2.85 at aa 23-44, sequence RGITAAEASLGVRQSTISTQLS 216591019848 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.6e-27 216591019849 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591019850 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591019851 DNA binding residues [nucleotide binding] 216591019852 dimerization interface [polypeptide binding]; other site 216591019853 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 1.6e-07 216591019854 HMMPfam hit to PF08281, Sigma-70, region, score 3.8e-06 216591019855 Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574 216591019856 YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300 216591019857 active site 216591019858 HMMPfam hit to PF07969, Amidohydrolase family, score 1.9e-64 216591019859 HMMPfam hit to PF01979, Amidohydrolase family, score 0.0021 216591019860 putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682 216591019861 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 216591019862 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 1.5e-14 216591019863 Protein of unknown function (DUF3138); Region: DUF3138; pfam11336 216591019864 Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642 216591019865 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; Region: AAT; pfam03417 216591019866 The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467 216591019867 HMMPfam hit to PF03417, Acyl-coenzyme A:6-aminopenicillanic acid acy, score 2.7e-06 216591019868 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591019869 D-galactonate transporter; Region: 2A0114; TIGR00893 216591019870 putative substrate translocation pore; other site 216591019871 10 probable transmembrane helices predicted for BCAM0427 by TMHMM2.0 at aa 83-105, 120-142, 171-193, 198-220, 276-298, 313-335, 348-367, 371-393, 406-428 and 433-455 216591019872 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.3e-62 216591019873 SH3 domain protein [Signal transduction mechanisms]; Region: COG3103 216591019874 Predicted transcriptional regulators [Transcription]; Region: COG1733 216591019875 HxlR-like helix-turn-helix; Region: HxlR; pfam01638 216591019876 HMMPfam hit to PF01638, HxlR-like helix-turn-helix, score 3.6e-38 216591019877 glutathionine S-transferase; Provisional; Region: PRK10542 216591019878 GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057 216591019879 C-terminal domain interface [polypeptide binding]; other site 216591019880 GSH binding site (G-site) [chemical binding]; other site 216591019881 dimer interface [polypeptide binding]; other site 216591019882 C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188 216591019883 dimer interface [polypeptide binding]; other site 216591019884 N-terminal domain interface [polypeptide binding]; other site 216591019885 substrate binding pocket (H-site) [chemical binding]; other site 216591019886 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 0.00045 216591019887 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 5.3e-09 216591019888 1 probable transmembrane helix predicted for BCAM0432 by TMHMM2.0 at aa 7-29 216591019889 Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538 216591019890 HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.8e-05 216591019891 HMMPfam hit to PF02321, Outer membrane efflux protein, score 5.3e-05 216591019892 copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783 216591019893 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591019894 Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604 216591019895 1 probable transmembrane helix predicted for BCAM0434 by TMHMM2.0 at aa 9-28 216591019896 Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696 216591019897 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 1.1e-224 216591019898 12 probable transmembrane helices predicted for BCAM0435 by TMHMM2.0 at aa 13-30, 342-359, 364-386, 390-412, 441-463, 483-505, 533-555, 869-891, 898-920, 924-946, 985-1004 and 1014-1036 216591019899 Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604 216591019900 1 probable transmembrane helix predicted for BCAM0436 by TMHMM2.0 at aa 7-29 216591019901 Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; Region: ECM27; COG0530 216591019902 Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699 216591019903 Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699 216591019904 10 probable transmembrane helices predicted for BCAM0437 by TMHMM2.0 at aa 4-26, 39-61, 76-98, 119-136, 140-162, 182-204, 219-238, 259-281, 291-308 and 313-335 216591019905 HMMPfam hit to PF01699, Sodium/calcium exchanger protein, score 1.5e-10 216591019906 HMMPfam hit to PF01699, Sodium/calcium exchanger protein, score 8e-13 216591019907 Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153 216591019908 putative metal binding site [ion binding]; other site 216591019909 putative homodimer interface [polypeptide binding]; other site 216591019910 putative homotetramer interface [polypeptide binding]; other site 216591019911 putative homodimer-homodimer interface [polypeptide binding]; other site 216591019912 putative allosteric switch controlling residues; other site 216591019913 HMMPfam hit to PF02583, Uncharacterised BCR, COG1937, score 3.7e-06 216591019914 Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230 216591019915 Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053 216591019916 HMMPfam hit to PF01545, Cation efflux family, score 4.2e-56 216591019917 6 probable transmembrane helices predicted for BCAM0439 by TMHMM2.0 at aa 32-54, 59-78, 98-120, 130-152, 203-225 and 230-252 216591019918 Protein of unknown function (DUF1289); Region: DUF1289; pfam06945 216591019919 HMMPfam hit to PF06945, Protein of unknown function (DUF1289), score 2.5e-16 216591019920 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591019921 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591019922 putative substrate translocation pore; other site 216591019923 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.4e-35 216591019924 10 probable transmembrane helices predicted for BCAM0441 by TMHMM2.0 at aa 34-56, 87-109, 151-168, 172-194, 214-236, 251-273, 285-304, 309-331, 344-366 and 370-392 216591019925 heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386 216591019926 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591019927 dimerization interface [polypeptide binding]; other site 216591019928 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591019929 dimer interface [polypeptide binding]; other site 216591019930 phosphorylation site [posttranslational modification] 216591019931 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591019932 ATP binding site [chemical binding]; other site 216591019933 Mg2+ binding site [ion binding]; other site 216591019934 G-X-G motif; other site 216591019935 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.1e-35 216591019936 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.8e-15 216591019937 HMMPfam hit to PF00672, HAMP domain, score 2.4e-12 216591019938 2 probable transmembrane helices predicted for BCAM0442 by TMHMM2.0 at aa 15-34 and 171-193 216591019939 heavy metal response regulator; Region: cztR_silR_copR; TIGR01387 216591019940 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591019941 active site 216591019942 phosphorylation site [posttranslational modification] 216591019943 intermolecular recognition site; other site 216591019944 dimerization interface [polypeptide binding]; other site 216591019945 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591019946 DNA binding site [nucleotide binding] 216591019947 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 9.9e-20 216591019948 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.3e-39 216591019949 Outer membrane efflux protein; Region: OEP; pfam02321 216591019950 Outer membrane efflux protein; Region: OEP; pfam02321 216591019951 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019952 HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.00054 216591019953 HMMPfam hit to PF02321, Outer membrane efflux protein, score 3.5e-05 216591019954 Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132 216591019955 Multicopper oxidase; Region: Cu-oxidase_3; pfam07732 216591019956 Multicopper oxidase; Region: Cu-oxidase_2; pfam07731 216591019957 HMMPfam hit to PF07732, Multicopper oxidase, score 6.2e-54 216591019958 HMMPfam hit to PF07731, Multicopper oxidase, score 4.7e-27 216591019959 PS00080 Multicopper oxidases signature 2. 216591019960 Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604 216591019961 CopC domain; Region: CopC; pfam04234 216591019962 HMMPfam hit to PF04234, Copper resistance protein CopC, score 6.6e-21 216591019963 2 probable transmembrane helices predicted for BCAM0449 by TMHMM2.0 at aa 9-28 and 89-108 216591019964 Copper resistance protein D; Region: CopD; cl00563 216591019965 HMMPfam hit to PF05425, Copper resistance protein D, score 5.6e-08 216591019966 8 probable transmembrane helices predicted for BCAM0450 by TMHMM2.0 at aa 13-35, 56-75, 95-117, 124-142, 157-179, 200-222, 237-259 and 289-311 216591019967 YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486 216591019968 generic binding surface I; other site 216591019969 generic binding surface II; other site 216591019970 Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283 216591019971 putative active site [active] 216591019972 putative catalytic site [active] 216591019973 putative Mg binding site IVb [ion binding]; other site 216591019974 putative phosphate binding site [ion binding]; other site 216591019975 putative DNA binding site [nucleotide binding]; other site 216591019976 putative Mg binding site IVa [ion binding]; other site 216591019977 1 probable transmembrane helix predicted for BCAM0451 by TMHMM2.0 at aa 7-29 216591019978 HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 1.8e-22 216591019979 Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939 216591019980 Serine carboxypeptidase; Region: Peptidase_S10; cl08270 216591019981 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019982 PS00012 Phosphopantetheine attachment site. 216591019983 HMMPfam hit to PF00450, Serine carboxypeptidase, score 9e-06 216591019984 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591019985 Frameshift after codon 148 216591019986 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 2.9e-11 216591019987 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.3e-05 216591019988 HMMPfam hit to PF01965, DJ-1/PfpI family, score 0.0003 216591019989 Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020 216591019990 conserved cys residue [active] 216591019991 1 probable transmembrane helix predicted for BCAM0456 by TMHMM2.0 at aa 7-24 216591019992 HMMPfam hit to PF01965, DJ-1/PfpI family, score 6.5e-14 216591019993 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591019994 Probable gene remnant. CDS lacks appropriate translational stop codon. Similar to the C-terminal region of Burkholderia cenocepacia HI2424 alcohol dehydrogenase GroES domain protein. UniProt:A0AXN7 (EMBL:CP000459 (359 aa) fasta scores: E()=4.4e-15, 85.246% id in 61 aa 216591019995 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 216591019996 cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402 216591019997 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591019998 catalytic residue [active] 216591019999 Putative phosphatase (DUF442); Region: DUF442; cl17385 216591020000 HMMPfam hit to PF04273, Protein of unknown function (DUF442), score 7.1e-22 216591020001 HMMPfam hit to PF00266, Aminotransferase class-V, score 7.5e-86 216591020002 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.00014 216591020003 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020004 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 216591020005 PS00017 ATP/GTP-binding site motif A (P-loop). 216591020006 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 216591020007 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 216591020008 Walker A/P-loop; other site 216591020009 ATP binding site [chemical binding]; other site 216591020010 Q-loop/lid; other site 216591020011 ABC transporter signature motif; other site 216591020012 Walker B; other site 216591020013 D-loop; other site 216591020014 H-loop/switch region; other site 216591020015 HMMPfam hit to PF00005, ABC transporter score 2.4e-65 216591020016 PS00211 ABC transporters family signature. 216591020017 PS00017 ATP/GTP-binding site motif A (P-loop). 216591020018 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591020019 dimer interface [polypeptide binding]; other site 216591020020 conserved gate region; other site 216591020021 putative PBP binding loops; other site 216591020022 ABC-ATPase subunit interface; other site 216591020023 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.1e-31 216591020024 4 probable transmembrane helices predicted for BCAM0461 by TMHMM2.0 at aa 15-37, 50-72, 87-104 and 185-207 216591020025 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591020026 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591020027 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591020028 substrate binding pocket [chemical binding]; other site 216591020029 membrane-bound complex binding site; other site 216591020030 hinge residues; other site 216591020031 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.1e-59 216591020032 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591020033 cystathionine beta-lyase; Provisional; Region: PRK07050 216591020034 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 216591020035 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591020036 catalytic residue [active] 216591020037 HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 1.1e-94 216591020038 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0046 216591020039 DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013 216591020040 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020041 The C-terminal substrate-domain of LysR-type transcriptional regulators involved in the catabolism of opines and that of related regulators, contains the type 2 periplasmic binding fold; Region: PBP2_LysR_opines_like; cd08415 216591020042 putative dimerization interface [polypeptide binding]; other site 216591020043 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.8e-16 216591020044 PS00228 Tubulin-beta mRNA autoregulation signal. 216591020045 Predicted helix-turn-helix motif with score 1296.000, SD 3.60 at aa 14-35, sequence GSTSKAAGVLEISQPAVSQSIR 216591020046 PS00044 Bacterial regulatory proteins, lysR family signature. 216591020047 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.5e-36 216591020048 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591020049 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591020050 putative substrate translocation pore; other site 216591020051 HMMPfam hit to PF00083, Sugar (and other) transporter score 8.9e-05 216591020052 11 probable transmembrane helices predicted for BCAM0465 by TMHMM2.0 at aa 15-37, 50-72, 82-104, 144-163, 167-189, 215-237, 252-274, 281-300, 305-327, 336-358 and 373-392 216591020053 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.7e-46 216591020054 PS00216 Sugar transport proteins signature 1. 216591020055 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591020056 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020057 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591020058 putative effector binding pocket; other site 216591020059 dimerization interface [polypeptide binding]; other site 216591020060 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.5e-16 216591020061 Predicted helix-turn-helix motif with score 1556.000, SD 4.49 at aa 17-38, sequence SSFAEAARQLGVTSSVVTNRIQ 216591020062 PS00044 Bacterial regulatory proteins, lysR family signature. 216591020063 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.9e-44 216591020064 3-hydroxyanthranilic acid dioxygenase; Region: 3-HAO; cl17399 216591020065 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591020066 Pseudomonas fluorescens 4-hydroxymuconic semialdehyde dehydrogenase-like; Region: ALDH_HMSADH_HapE; cd07115 216591020067 NAD(P) binding site [chemical binding]; other site 216591020068 catalytic residues [active] 216591020069 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 5.9e-270 216591020070 PS00070 Aldehyde dehydrogenases cysteine active site. 216591020071 Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454 216591020072 Maleylacetate reductase is involved in many aromatic compounds degradation pathways of aerobic microbes; Region: MAR; cd08177 216591020073 active site 216591020074 dimer interface [polypeptide binding]; other site 216591020075 metal binding site [ion binding]; metal-binding site 216591020076 HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 2.8e-18 216591020077 YciI-like protein; Reviewed; Region: PRK12863 216591020078 HMMPfam hit to PF03795, YCII-related domain, score 9.3e-17 216591020079 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467 216591020080 iron-sulfur cluster [ion binding]; other site 216591020081 [2Fe-2S] cluster binding site [ion binding]; other site 216591020082 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 1.5e-05 216591020083 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591020084 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591020085 trimer interface [polypeptide binding]; other site 216591020086 eyelet of channel; other site 216591020087 HMMPfam hit to PF00267, Gram-negative porin, score 0.0052 216591020088 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591020089 glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331 216591020090 Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans). The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714 216591020091 glutaminase active site [active] 216591020092 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 216591020093 dimer interface [polypeptide binding]; other site 216591020094 active site 216591020095 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 216591020096 dimer interface [polypeptide binding]; other site 216591020097 active site 216591020098 HMMPfam hit to PF01380, SIS domain, score 1.1e-23 216591020099 HMMPfam hit to PF01380, SIS domain, score 3.8e-31 216591020100 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 2.6e-35 216591020101 PS00443 Glutamine amidotransferases class-II active site. 216591020102 Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412 216591020103 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591020104 AsnC family; Region: AsnC_trans_reg; pfam01037 216591020105 HMMPfam hit to PF01037, AsnC family, score 1.7e-20 216591020106 Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557 216591020107 oligomerization interface [polypeptide binding]; other site 216591020108 active site 216591020109 metal binding site [ion binding]; metal-binding site 216591020110 HMMPfam hit to PF02548, Ketopantoate hydroxymethyltransferase, score 2.2e-104 216591020111 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 216591020112 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591020113 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591020114 Predicted helix-turn-helix motif with score 1705.000, SD 4.99 at aa 187-208, sequence RSLDEWGRQVGATRRTLSRLFR 216591020115 methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901 216591020116 The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445 216591020117 DNA binding site [nucleotide binding] 216591020118 active site 216591020119 HMMPfam hit to PF01035, 6-O-methylguanine DNA methyltransferase, score 1.2e-46 216591020120 PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 216591020121 Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169 216591020122 Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805 216591020123 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591020124 AlkA N-terminal domain; Region: AlkA_N; pfam06029 216591020125 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786 216591020126 HMMPfam hit to PF06029, AlkA N-terminal domain, score 1.2e-37 216591020127 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix, score 2.7e-08 216591020128 PS00041 Bacterial regulatory proteins, araC family signature. 216591020129 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix, score 1.7e-06 216591020130 Predicted helix-turn-helix motif with score 1671.000, SD 4.88 at aa 101-122, sequence HSVAALARRIGVTERHLRRIFG 216591020131 PS00136 Serine proteases, subtilase family, aspartic acid active site. 216591020132 HMMPfam hit to PF02805, Metal binding domain of Ada, score 3.1e-41 216591020133 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591020134 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591020135 putative substrate translocation pore; other site 216591020136 HMMPfam hit to PF00083, Sugar (and other) transporter score 0.00017 216591020137 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.2e-60 216591020138 9 probable transmembrane helices predicted for BCAM0484 by TMHMM2.0 at aa 69-91, 101-123, 159-181, 185-207, 251-270, 285-307, 327-358, 378-397 and 410-432 216591020139 PS00211 ABC transporters family signature. 216591020140 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591020141 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591020142 DNA binding site [nucleotide binding] 216591020143 domain linker motif; other site 216591020144 Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267 216591020145 dimerization interface [polypeptide binding]; other site 216591020146 ligand binding site [chemical binding]; other site 216591020147 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 1.2e-12 216591020148 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 1.7e-08 216591020149 Predicted helix-turn-helix motif with score 1897.000, SD 5.65 at aa 43-64, sequence PTIRDVAAEAGVSVATVSKYVN 216591020150 PS00356 Bacterial regulatory proteins, lacI family signature. 216591020151 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591020152 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 216591020153 NAD(P) binding site [chemical binding]; other site 216591020154 active site 216591020155 HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.00093 216591020156 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.0049 216591020157 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 3e-08 216591020158 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 2.9e-08 216591020159 HMMPfam hit to PF07993, Male sterility protein, score 2.6e-05 216591020160 Protein of unknown function (DUF1330); Region: DUF1330; pfam07045 216591020161 HMMPfam hit to PF07045, Protein of unknown function (DUF1330), score 1.3e-22 216591020162 Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600 216591020163 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 216591020164 DNA binding residues [nucleotide binding] 216591020165 HMMPfam hit to PF00376, MerR family regulatory protein, score 1.8e-10 216591020166 PS00552 Bacterial regulatory proteins, merR family signature. 216591020167 Predicted helix-turn-helix motif with score 1323.000, SD 3.69 at aa 5-26, sequence MKIGELAKASGLAASRIRFYEA 216591020168 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 216591020169 Old yellow enzyme (OYE)-related FMN binding domain, group 2. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_2_FMN; cd04733 216591020170 putative active site [active] 216591020171 putative FMN binding site [chemical binding]; other site 216591020172 putative substrate binding site [chemical binding]; other site 216591020173 putative catalytic residue [active] 216591020174 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 7.6e-57 216591020175 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 216591020176 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591020177 N-terminal plug; other site 216591020178 ligand-binding site [chemical binding]; other site 216591020179 HMMPfam hit to PF00593, TonB dependent receptor, score 5.6e-16 216591020180 PS00455 Putative AMP-binding domain signature. 216591020181 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.9e-20 216591020182 Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182 216591020183 PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172 216591020184 PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703 216591020185 6 probable transmembrane helices predicted for BCAM0492 by TMHMM2.0 at aa 27-49, 156-178, 199-221, 320-342, 407-429 and 454-476 216591020186 HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.0038 216591020187 HMMPfam hit to PF03413, Peptidase propeptide and YPEB domain, score 0.00036 216591020188 HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.028 216591020189 HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.092 216591020190 HMMPfam hit to PF03413, Peptidase propeptide and YPEB domain, score 0.00064 216591020191 HMMPfam hit to PF03929, PepSY-associated TM helix, score 1.2 216591020192 2 probable transmembrane helices predicted for BCAM0493 by TMHMM2.0 at aa 17-39 and 108-130 216591020193 Predicted helix-turn-helix motif with score 1128.000, SD 3.03 at aa 96-117, sequence FMLTSLAAHRDIHPQTLRTLFR 216591020194 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591020195 6 probable transmembrane helices predicted for BCAM0496 by TMHMM2.0 at aa 15-37, 44-66, 70-92, 119-141, 154-176 and 189-208 216591020196 HMMPfam hit to PF01810, LysE type translocator, score 3.2e-24 216591020197 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020198 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020199 PS00369 PTS HPR component histidine phosphorylation site signature. 216591020200 NADP+-dependent non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase and ALDH family 11; Region: ALDH_F11_NP-GAPDH; cd07082 216591020201 NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012 216591020202 tetrameric interface [polypeptide binding]; other site 216591020203 activator binding site; other site 216591020204 NADP binding site [chemical binding]; other site 216591020205 substrate binding site [chemical binding]; other site 216591020206 catalytic residues [active] 216591020207 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.6e-75 216591020208 PS00070 Aldehyde dehydrogenases cysteine active site. 216591020209 Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; Region: Fiu; COG4774 216591020210 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591020211 N-terminal plug; other site 216591020212 ligand-binding site [chemical binding]; other site 216591020213 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 4.1e-25 216591020214 HMMPfam hit to PF00593, TonB dependent receptor, score 1.7e-30 216591020215 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020216 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591020217 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591020218 dimerization interface [polypeptide binding]; other site 216591020219 HMMPfam hit to PF03466, LysR substrate binding domain, score 8.3e-35 216591020220 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.1e-17 216591020221 PS00044 Bacterial regulatory proteins, lysR family signature. 216591020222 Predicted helix-turn-helix motif with score 1735.000, SD 5.10 at aa 14-35, sequence ESFTHAAKELFLTESAVSRQIA 216591020223 Domain of unknown function (DUF1338); Region: DUF1338; pfam07063 216591020224 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020225 CsbD-like; Region: CsbD; cl17424 216591020226 HMMPfam hit to PF05532, CsbD-like, score 6.1e-19 216591020227 outer membrane lipoprotein; Provisional; Region: PRK11023 216591020228 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 1e-12 216591020229 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459 216591020230 PAS domain; Region: PAS_9; pfam13426 216591020231 PAS domain S-box; Region: sensory_box; TIGR00229 216591020232 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591020233 putative active site [active] 216591020234 heme pocket [chemical binding]; other site 216591020235 PAS domain S-box; Region: sensory_box; TIGR00229 216591020236 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591020237 putative active site [active] 216591020238 heme pocket [chemical binding]; other site 216591020239 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591020240 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591020241 DNA binding residues [nucleotide binding] 216591020242 dimerization interface [polypeptide binding]; other site 216591020243 HMMPfam hit to PF00989, PAS fold, score 0.00073 216591020244 HMMPfam hit to PF08448, PAS fold, score 0.00033 216591020245 HMMPfam hit to PF00989, PAS fold, score 0.039 216591020246 HMMPfam hit to PF08447, PAS fold, score 0.0026 216591020247 HMMPfam hit to PF08281, Sigma-70, region, score 0.0018 216591020248 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 1.4e-19 216591020249 Predicted helix-turn-helix motif with score 1241.000, SD 3.41 at aa 446-467, sequence LADKEIAGRLGLAPNTVRNHVA 216591020250 CsbD-like; Region: CsbD; pfam05532 216591020251 HMMPfam hit to PF05532, CsbD-like, score 1.4e-19 216591020252 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591020253 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 216591020254 dimerization interface [polypeptide binding]; other site 216591020255 ligand binding site [chemical binding]; other site 216591020256 HMMPfam hit to PF01094, Receptor family ligand binding region, score 7.6e-47 216591020257 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591020258 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 4.6e-84 216591020259 2 probable transmembrane helices predicted for BCAM0510 by TMHMM2.0 at aa 15-37 and 46-68 216591020260 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 216591020261 Beta-lactamase; Region: Beta-lactamase; pfam00144 216591020262 HMMPfam hit to PF00144, Beta-lactamase, score 1.6e-74 216591020263 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075 216591020264 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591020265 catalytic residue [active] 216591020266 HMMPfam hit to PF00266, Aminotransferase class-V, score 0.00025 216591020267 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430 216591020268 Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376 216591020269 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591020270 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591020271 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 8.6e-13 216591020272 Predicted helix-turn-helix motif with score 1543.000, SD 4.44 at aa 29-50, sequence LNYRDLANEVGIKAASIYHHFE 216591020273 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591020274 GST_N family, Saccharomyces cerevisiae GTT2-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT2. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing...; Region: GST_N_GTT2_like; cd03051 216591020275 putative C-terminal domain interface [polypeptide binding]; other site 216591020276 putative GSH binding site (G-site) [chemical binding]; other site 216591020277 putative dimer interface [polypeptide binding]; other site 216591020278 C-terminal, alpha helical domain of GTT2-like Glutathione S-transferases; Region: GST_C_GTT2_like; cd03182 216591020279 putative N-terminal domain interface [polypeptide binding]; other site 216591020280 putative dimer interface [polypeptide binding]; other site 216591020281 putative substrate binding pocket (H-site) [chemical binding]; other site 216591020282 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 1.6e-15 216591020283 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 7.4e-07 216591020284 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262 216591020285 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591020286 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 6.4e-09 216591020287 PS00079 Multicopper oxidases signature 1. 216591020288 pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424 216591020289 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020290 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591020291 dimerization interface [polypeptide binding]; other site 216591020292 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.5e-18 216591020293 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.3e-16 216591020294 Predicted helix-turn-helix motif with score 1208.000, SD 3.30 at aa 31-52, sequence GSLTRVAEHMASSQPAVTNALS 216591020295 malic enzyme; Reviewed; Region: PRK12861 216591020296 Malic enzyme, N-terminal domain; Region: malic; pfam00390 216591020297 NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311 216591020298 putative NAD(P) binding site [chemical binding]; other site 216591020299 Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280 216591020300 HMMPfam hit to PF00390, Malic enzyme, N-terminal domain, score 2.5e-76 216591020301 HMMPfam hit to PF03949, Malic enzyme, NAD binding domain, score 1.4e-124 216591020302 PS00017 ATP/GTP-binding site motif A (P-loop). 216591020303 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020304 HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 5.7e-109 216591020305 transposase/IS protein; Provisional; Region: PRK09183 216591020306 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591020307 Walker A motif; other site 216591020308 ATP binding site [chemical binding]; other site 216591020309 Walker B motif; other site 216591020310 HMMPfam hit to PF01695, IstB-like ATP binding protein, score 9.6e-88 216591020311 PS00017 ATP/GTP-binding site motif A (P-loop). 216591020312 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584 216591020313 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 216591020314 DNA-binding interface [nucleotide binding]; DNA binding site 216591020315 Integrase core domain; Region: rve; pfam00665 216591020316 HMMPfam hit to PF00665, Integrase core domain, score 2.7e-25 216591020317 HMMPfam hit to PF02796, Helix-turn-helix domain of resolvase, score 0.0028 216591020318 Predicted helix-turn-helix motif with score 2020.000, SD 6.07 at aa 18-39, sequence VSEREIARRLGISRNTVARYLS 216591020319 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591020320 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 216591020321 Walker A motif; other site 216591020322 ATP binding site [chemical binding]; other site 216591020323 Walker B motif; other site 216591020324 arginine finger; other site 216591020325 Predicted helix-turn-helix motif with score 1430.000, SD 4.06 at aa 367-388, sequence FSLTDIGEVAGKDKSTVSRQIG 216591020326 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.2e-37 216591020327 PS00017 ATP/GTP-binding site motif A (P-loop). 216591020328 Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436 216591020329 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591020330 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591020331 homodimer interface [polypeptide binding]; other site 216591020332 catalytic residue [active] 216591020333 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.5e-17 216591020334 Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxase_2; pfam12766 216591020335 PPOX class probable FMN-dependent enzyme, alr4036 family; Region: PPOX_FMN_cyano; TIGR04026 216591020336 HMMPfam hit to PF01243, Pyridoxamine 5'-phosphate oxidase, score 1.9e-06 216591020337 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591020338 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020339 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591020340 dimerization interface [polypeptide binding]; other site 216591020341 substrate binding pocket [chemical binding]; other site 216591020342 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-31 216591020343 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.4e-14 216591020344 PS00044 Bacterial regulatory proteins, lysR family signature. 216591020345 Predicted helix-turn-helix motif with score 1579.000, SD 4.56 at aa 24-45, sequence LNFRAAADEIGVTQGAVAQQVR 216591020346 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565 216591020347 putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR; Region: BKR_like_SDR_like; cd05344 216591020348 putative NAD(P) binding site [chemical binding]; other site 216591020349 putative active site [active] 216591020350 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.1e-08 216591020351 Epoxide hydrolase N terminus; Region: EHN; pfam06441 216591020352 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591020353 1 probable transmembrane helix predicted for BCAM0529 by TMHMM2.0 at aa 13-35 216591020354 HMMPfam hit to PF06441, Epoxide hydrolase N terminus, score 3.6e-58 216591020355 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.7e-07 216591020356 PS00294 Prenyl group binding site (CAAX box). 216591020357 3 probable transmembrane helices predicted for BCAM0529A by TMHMM2.0 at aa 13-35, 55-77 and 89-111 216591020358 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020359 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591020360 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591020361 DNA-binding site [nucleotide binding]; DNA binding site 216591020362 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591020363 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591020364 homodimer interface [polypeptide binding]; other site 216591020365 catalytic residue [active] 216591020366 HMMPfam hit to PF00155, Aminotransferase class I and II, score 4e-19 216591020367 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 6.7e-14 216591020368 Predicted helix-turn-helix motif with score 1263.000, SD 3.49 at aa 33-54, sequence PSIREYAEASGCSKNTVISAFE 216591020369 Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644 216591020370 homodimer interface [polypeptide binding]; other site 216591020371 catalytic residues [active] 216591020372 NAD binding site [chemical binding]; other site 216591020373 substrate binding pocket [chemical binding]; other site 216591020374 flexible flap; other site 216591020375 PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 216591020376 PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 216591020377 PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 216591020378 2 probable transmembrane helices predicted for BCAM0532 by TMHMM2.0 at aa 43-65 and 75-97 216591020379 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020380 10 probable transmembrane helices predicted for BCAM0533 by TMHMM2.0 at aa 7-29, 39-61, 108-130, 140-157, 162-184, 188-207, 308-330, 356-378, 391-410 and 414-436 216591020381 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591020382 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 2.7e-07 216591020383 1 probable transmembrane helix predicted for BCAM0535 by TMHMM2.0 at aa 13-35 216591020384 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591020385 1 probable transmembrane helix predicted for BCAM0536 by TMHMM2.0 at aa 44-66 216591020386 methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657 216591020387 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591020388 amidase; Provisional; Region: PRK07487 216591020389 Amidase; Region: Amidase; cl11426 216591020390 HMMPfam hit to PF01425, Amidase, score 2.3e-74 216591020391 PS00571 Amidases signature. 216591020392 Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins; Region: RHOD_1; cd01522 216591020393 active site residue [active] 216591020394 HMMPfam hit to PF00581, Rhodanese-like domain, score 1.2e-08 216591020395 serine O-acetyltransferase; Region: cysE; TIGR01172 216591020396 Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354 216591020397 trimer interface [polypeptide binding]; other site 216591020398 active site 216591020399 substrate binding site [chemical binding]; other site 216591020400 CoA binding site [chemical binding]; other site 216591020401 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.52 216591020402 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.39 216591020403 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 28 216591020404 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591020405 non-specific DNA binding site [nucleotide binding]; other site 216591020406 salt bridge; other site 216591020407 sequence-specific DNA binding site [nucleotide binding]; other site 216591020408 HMMPfam hit to PF01381, Helix-turn-helix, score 5.5e-17 216591020409 Predicted helix-turn-helix motif with score 1705.000, SD 4.99 at aa 21-42, sequence WSQEQLAEHAGLNRSYVGEIER 216591020410 Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520 216591020411 Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453 216591020412 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591020413 catalytic residue [active] 216591020414 HMMPfam hit to PF00266, Aminotransferase class-V, score 2.5e-205 216591020415 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.00046 216591020416 Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452 216591020417 nucleotide binding site [chemical binding]; other site 216591020418 substrate binding site [chemical binding]; other site 216591020419 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 216591020420 active site 216591020421 phosphorylation site [posttranslational modification] 216591020422 HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phosph, score 5.7e-06 216591020423 PS00372 PTS EIIA domains phosphorylation site signature 2. 216591020424 1 probable transmembrane helix predicted for BCAM0545a by TMHMM2.0 at aa 37-59 216591020425 PS00190 Cytochrome c family heme-binding site signature. 216591020426 LysE type translocator; Region: LysE; cl00565 216591020427 HMMPfam hit to PF01810, LysE type translocator, score 6.1e-30 216591020428 5 probable transmembrane helices predicted for BCAM0547 by TMHMM2.0 at aa 7-29, 44-66, 116-138, 148-170 and 183-202 216591020429 chaperonin GroEL; Reviewed; Region: groEL; PRK12849 216591020430 GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344 216591020431 ring oligomerisation interface [polypeptide binding]; other site 216591020432 ATP/Mg binding site [chemical binding]; other site 216591020433 stacking interactions; other site 216591020434 hinge regions; other site 216591020435 HMMPfam hit to PF00118, TCP-1/cpn60 chaperonin family, score 2e-197 216591020436 PS00296 Chaperonins cpn60 signature. 216591020437 Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320 216591020438 oligomerisation interface [polypeptide binding]; other site 216591020439 mobile loop; other site 216591020440 roof hairpin; other site 216591020441 HMMPfam hit to PF00166, Chaperonin 10 Kd subunit, score 6.1e-49 216591020442 PS00681 Chaperonins cpn10 signature. 216591020443 Secretory lipase; Region: LIP; pfam03583 216591020444 HMMPfam hit to PF03583, Secretory lipase, score 8.6e-08 216591020445 Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; pfam00596 216591020446 active site 216591020447 Zn2+ binding site [ion binding]; other site 216591020448 intersubunit interface [polypeptide binding]; other site 216591020449 HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 3.4e-05 216591020450 PS00017 ATP/GTP-binding site motif A (P-loop). 216591020451 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591020452 Walker A motif; other site 216591020453 ATP binding site [chemical binding]; other site 216591020454 Walker B motif; other site 216591020455 arginine finger; other site 216591020456 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 2.2e-146 216591020457 HMMPfam hit to PF07728, ATPase family associated with various, score 0.00015 216591020458 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591020459 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591020460 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591020461 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591020462 putative PBP binding loops; other site 216591020463 dimer interface [polypeptide binding]; other site 216591020464 ABC-ATPase subunit interface; other site 216591020465 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3.3e-17 216591020466 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020467 6 probable transmembrane helices predicted for BCAM0553 by TMHMM2.0 at aa 13-30, 73-95, 108-125, 130-149, 174-196 and 222-244 216591020468 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591020469 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427 216591020470 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.4e-21 216591020471 5 probable transmembrane helices predicted for BCAM0554 by TMHMM2.0 at aa 26-43, 84-103, 118-137, 144-163 and 238-260 216591020472 PS00237 G-protein coupled receptors signature. 216591020473 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 216591020474 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432 216591020475 PS00017 ATP/GTP-binding site motif A (P-loop). 216591020476 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 216591020477 alkanesulfonate monooxygenase, FMNH(2)-dependent; Region: alk_sulf_monoox; TIGR03565 216591020478 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892 216591020479 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 1.5e-05 216591020480 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 216591020481 Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810 216591020482 Gram-negative bacterial tonB protein; Region: TonB; pfam03544 216591020483 HMMPfam hit to PF03544, Gram-negative bacterial tonB protein, score 2.6e-09 216591020484 Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811 216591020485 3 probable transmembrane helices predicted for BCAM0560 by TMHMM2.0 at aa 13-35, 120-142 and 166-188 216591020486 HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 1e-40 216591020487 Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848 216591020488 TolR protein; Region: tolR; TIGR02801 216591020489 HMMPfam hit to PF02472, Biopolymer transport protein ExbD/TolR, score 2.4e-24 216591020490 1 probable transmembrane helix predicted for BCAM0561 by TMHMM2.0 at aa 20-42 216591020491 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 216591020492 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591020493 putative substrate translocation pore; other site 216591020494 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591020495 12 probable transmembrane helices predicted for BCAM0563 by TMHMM2.0 at aa 20-42, 52-74, 81-103, 107-129, 141-163, 168-190, 223-245, 255-277, 284-302, 306-328, 341-363 and 367-389 216591020496 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.2e-16 216591020497 Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629 216591020498 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591020499 N-terminal plug; other site 216591020500 ligand-binding site [chemical binding]; other site 216591020501 1 probable transmembrane helix predicted for BCAM0564 by TMHMM2.0 at aa 21-43 216591020502 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 6.1e-18 216591020503 HMMPfam hit to PF00593, TonB dependent receptor, score 2.4e-20 216591020504 Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR7; cd08276 216591020505 NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604 216591020506 putative NAD(P) binding site [chemical binding]; other site 216591020507 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.2e-33 216591020508 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 3.2e-15 216591020509 transcriptional regulator; Provisional; Region: PRK10632 216591020510 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020511 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_6; cd08475 216591020512 putative effector binding pocket; other site 216591020513 putative dimerization interface [polypeptide binding]; other site 216591020514 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 7.4e-14 216591020515 Predicted helix-turn-helix motif with score 1526.000, SD 4.38 at aa 18-39, sequence GSFAAAALRLGMTRSAVAKIVA 216591020516 PS00044 Bacterial regulatory proteins, lysR family signature. 216591020517 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.1e-48 216591020518 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591020519 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591020520 putative substrate translocation pore; other site 216591020521 12 probable transmembrane helices predicted for BCAM0567 by TMHMM2.0 at aa 20-42, 57-79, 86-105, 110-132, 145-167, 177-196, 248-270, 280-299, 312-331, 336-358, 365-387 and 402-419 216591020522 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.8e-50 216591020523 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020524 short chain dehydrogenase; Provisional; Region: PRK07577 216591020525 classical (c) SDRs; Region: SDR_c; cd05233 216591020526 NAD(P) binding site [chemical binding]; other site 216591020527 active site 216591020528 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.6e-27 216591020529 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00042 216591020530 Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119 216591020531 Sulfatase; Region: Sulfatase; cl17466 216591020532 Sulfatase; Region: Sulfatase; cl17466 216591020533 Sulfatase; Region: Sulfatase; cl17466 216591020534 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020535 HMMPfam hit to PF00884, Sulfatase, score 3.5e-37 216591020536 PS00149 Sulfatases signature 2. 216591020537 Uncharacterized conserved protein [Function unknown]; Region: COG1262 216591020538 Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781 216591020539 1 probable transmembrane helix predicted for BCAM0570 by TMHMM2.0 at aa 5-27 216591020540 HMMPfam hit to PF03781, Domain of unknown function (DUF323), score 4.6e-70 216591020541 NLPA lipoprotein; Region: Lipoprotein_9; pfam03180 216591020542 HMMPfam hit to PF03180, NLPA lipoprotein, score 3.8e-41 216591020543 HMMPfam hit to PF03692, Uncharacterised protein family (UPF0153), score 0.0062 216591020544 Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022 216591020545 4 probable transmembrane helices predicted for BCAM0574 by TMHMM2.0 at aa 12-31, 36-53, 60-77 and 92-109 216591020546 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591020547 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020548 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591020549 dimerization interface [polypeptide binding]; other site 216591020550 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.8e-31 216591020551 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.2e-13 216591020552 Predicted helix-turn-helix motif with score 1177.000, SD 3.20 at aa 16-37, sequence RNFRTTAAALHATPAAISQRLK 216591020553 hypothetical protein; Provisional; Region: PRK05463 216591020554 HMMPfam hit to PF07286, Protein of unknown function (DUF1445), score 1e-92 216591020555 benzoate transport; Region: 2A0115; TIGR00895 216591020556 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591020557 putative substrate translocation pore; other site 216591020558 HMMPfam hit to PF00083, Sugar (and other) transporter score 9.4e-08 216591020559 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.6e-50 216591020560 12 probable transmembrane helices predicted for BCAM0577 by TMHMM2.0 at aa 52-69, 73-92, 104-121, 125-147, 159-181, 191-208, 249-271, 276-298, 311-328, 338-360, 373-392 and 397-419 216591020561 PS00217 Sugar transport proteins signature 2. 216591020562 5-oxoprolinase; Region: PLN02666 216591020563 Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378 216591020564 Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968 216591020565 N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146 216591020566 HMMPfam hit to PF05378, Hydantoinase/oxoprolinase N-terminal r, score 2.1e-83 216591020567 Predicted helix-turn-helix motif with score 1213.000, SD 3.32 at aa 187-208, sequence RMLAELARRIGFTQVSVSHEVS 216591020568 HMMPfam hit to PF01968, Hydantoinase/oxoprolinase, score 6.9e-130 216591020569 HMMPfam hit to PF02538, Hydantoinase B/oxoprolinase, score 1.4e-279 216591020570 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020571 RNase II stability modulator; Provisional; Region: PRK10060 216591020572 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591020573 metal binding site [ion binding]; metal-binding site 216591020574 active site 216591020575 I-site; other site 216591020576 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 216591020577 HMMPfam hit to PF00990, GGDEF domain, score 2.4e-55 216591020578 HMMPfam hit to PF00563, EAL domain, score 2.5e-118 216591020579 enoyl-CoA hydratase; Validated; Region: PRK08788 216591020580 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591020581 substrate binding site [chemical binding]; other site 216591020582 oxyanion hole (OAH) forming residues; other site 216591020583 trimer interface [polypeptide binding]; other site 216591020584 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 1.2e-08 216591020585 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591020586 Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969 216591020587 Transglutaminase-like superfamily; Region: Transglut_core; pfam01841 216591020588 PS00306 Caseins alpha/beta signature. 216591020589 Cupin; Region: Cupin_6; pfam12852 216591020590 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591020591 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591020592 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591020593 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 9.4e-10 216591020594 PS00041 Bacterial regulatory proteins, araC family signature. 216591020595 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 7.9e-10 216591020596 PS00041 Bacterial regulatory proteins, araC family signature. 216591020597 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591020598 putative substrate translocation pore; other site 216591020599 12 probable transmembrane helices predicted for BCAM0584 by TMHMM2.0 at aa 20-42, 55-77, 87-104, 111-133, 148-170, 175-197, 217-239, 246-268, 283-302, 309-331, 341-363 and 370-392 216591020600 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.9e-49 216591020601 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591020602 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 216591020603 active site 216591020604 catalytic tetrad [active] 216591020605 HMMPfam hit to PF00248, Aldo/keto reductase family, score 1.3e-46 216591020606 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591020607 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020608 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474 216591020609 putative effector binding pocket; other site 216591020610 putative dimerization interface [polypeptide binding]; other site 216591020611 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.9e-17 216591020612 Predicted helix-turn-helix motif with score 1157.000, SD 3.13 at aa 18-39, sequence GGFRDAARMTGLSASGLSEAVR 216591020613 PS00044 Bacterial regulatory proteins, lysR family signature. 216591020614 HMMPfam hit to PF03466, LysR substrate binding domain, score 7.8e-31 216591020615 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 216591020616 Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714 216591020617 tetramer interface [polypeptide binding]; other site 216591020618 active site 216591020619 Mg2+/Mn2+ binding site [ion binding]; other site 216591020620 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591020621 MarR family; Region: MarR_2; pfam12802 216591020622 HMMPfam hit to PF03551, Transcriptional regulator PadR-like family, score 0.00033 216591020623 HMMPfam hit to PF01047, MarR family, score 8.4e-15 216591020624 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591020625 GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046 216591020626 putative C-terminal domain interface [polypeptide binding]; other site 216591020627 putative GSH binding site (G-site) [chemical binding]; other site 216591020628 putative dimer interface [polypeptide binding]; other site 216591020629 C-terminal, alpha helical domain of an unknown subfamily 8 of Glutathione S-transferases; Region: GST_C_8; cd03207 216591020630 dimer interface [polypeptide binding]; other site 216591020631 N-terminal domain interface [polypeptide binding]; other site 216591020632 putative substrate binding pocket (H-site) [chemical binding]; other site 216591020633 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 1.1e-19 216591020634 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 3.4e-08 216591020635 flavin mononucleotide phosphatase; Provisional; Region: PRK10748 216591020636 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591020637 motif II; other site 216591020638 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 3.3e-19 216591020639 Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; Region: COG2423 216591020640 ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400 216591020641 HMMPfam hit to PF02423, Ornithine cyclodeaminase/mu-crystalli, score 2.1e-54 216591020642 Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616 216591020643 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes Similar to D-Serine Dehydratase and D-Threonine Aldolase, Unknown Group 1; Region: PLPDE_III_DSD_D-TA_like_1; cd06812 216591020644 dimer interface [polypeptide binding]; other site 216591020645 active site 216591020646 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 216591020647 substrate binding site [chemical binding]; other site 216591020648 catalytic residue [active] 216591020649 HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 2.6e-09 216591020650 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591020651 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020652 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591020653 dimerization interface [polypeptide binding]; other site 216591020654 HMMPfam hit to PF03466, LysR substrate binding domain, score 3e-31 216591020655 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.2e-17 216591020656 PS00044 Bacterial regulatory proteins, lysR family signature. 216591020657 Predicted helix-turn-helix motif with score 1486.000, SD 4.25 at aa 17-38, sequence RSLAAAARLLDLTPPAVTIRLQ 216591020658 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020659 aminoethylphosphonate catabolism associated LysR family transcriptional regulator; Region: phn_lysR; TIGR03339 216591020660 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591020661 dimerization interface [polypeptide binding]; other site 216591020662 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2e-17 216591020663 Predicted helix-turn-helix motif with score 1463.000, SD 4.17 at aa 16-37, sequence GGFTAAARALSTSQTTITSQIQ 216591020664 HMMPfam hit to PF03466, LysR substrate binding domain, score 8.1e-43 216591020665 Hydroxyethylphosphoate dehydrogenase (HEPD) catalyzes the reduction of phosphonoacetaldehyde (PnAA) to hydroxyethylphosphoate (HEP); Region: HEPD; cd08182 216591020666 Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465 216591020667 putative active site [active] 216591020668 metal binding site [ion binding]; metal-binding site 216591020669 HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 9.2e-22 216591020670 PS00913 Iron-containing alcohol dehydrogenases signature 1. 216591020671 benzoate transport; Region: 2A0115; TIGR00895 216591020672 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591020673 putative substrate translocation pore; other site 216591020674 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591020675 12 probable transmembrane helices predicted for BCAM0597 by TMHMM2.0 at aa 20-37, 63-85, 92-114, 118-140, 153-175, 181-200, 279-301, 311-333, 340-359, 364-386, 399-421 and 431-453 216591020676 HMMPfam hit to PF00083, Sugar (and other) transporter score 2.1e-10 216591020677 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3e-34 216591020678 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020679 PS00216 Sugar transport proteins signature 1. 216591020680 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992 216591020681 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591020682 HMMPfam hit to PF03486, HI0933-like protein, score 0.00049 216591020683 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 1.6e-07 216591020684 1 probable transmembrane helix predicted for BCAM0598 by TMHMM2.0 at aa 7-24 216591020685 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591020686 Predicted transcriptional regulator [Transcription]; Region: COG1959 216591020687 Transcriptional regulator; Region: Rrf2; pfam02082 216591020688 HMMPfam hit to PF02082, Transcriptional regulator, score 2.5e-32 216591020689 HMMPfam hit to PF08279, HTH domain, score 0.0015 216591020690 Predicted helix-turn-helix motif with score 1059.000, SD 2.79 at aa 24-45, sequence LTSETIATMLCTNPVVVRRLLG 216591020691 Domain of unknown function (DUF2760); Region: DUF2760; pfam10816 216591020692 Nucleotide-binding domain of the HSP70 family; Region: HSP70_NBD; cd10170 216591020693 nucleotide binding site [chemical binding]; other site 216591020694 putative NEF/HSP70 interaction site [polypeptide binding]; other site 216591020695 SBD interface [polypeptide binding]; other site 216591020696 PS00297 Heat shock hsp70 proteins family signature 1. 216591020697 Nucleotide-binding domain of the HSP70 family; Region: HSP70_NBD; cd10170 216591020698 nucleotide binding site [chemical binding]; other site 216591020699 putative NEF/HSP70 interaction site [polypeptide binding]; other site 216591020700 SBD interface [polypeptide binding]; other site 216591020701 DNA-K related protein; Region: DUF3731; pfam12531 216591020702 Uncharacterized protein conserved in bacteria containing a pentein-type domain [Function unknown]; Region: COG4874 216591020703 Amidinotransferase; Region: Amidinotransf; pfam02274 216591020704 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020705 ornithine cyclodeaminase; Validated; Region: PRK07589 216591020706 ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400 216591020707 HMMPfam hit to PF02423, Ornithine cyclodeaminase/mu-crystalli, score 1e-118 216591020708 PS00017 ATP/GTP-binding site motif A (P-loop). 216591020709 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591020710 AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404 216591020711 putative DNA binding site [nucleotide binding]; other site 216591020712 putative Zn2+ binding site [ion binding]; other site 216591020713 AsnC family; Region: AsnC_trans_reg; pfam01037 216591020714 HMMPfam hit to PF01037, AsnC family, score 3.9e-17 216591020715 Carboxymuconolactone decarboxylase family; Region: CMD; cl00460 216591020716 uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926 216591020717 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 3.4e-16 216591020718 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950; cl17731 216591020719 Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072 216591020720 FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454 216591020721 hydroxyglutarate oxidase; Provisional; Region: PRK11728 216591020722 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.0015 216591020723 HMMPfam hit to PF01494, FAD binding domain, score 0.0052 216591020724 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591020725 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020726 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591020727 dimerization interface [polypeptide binding]; other site 216591020728 HMMPfam hit to PF03466, LysR substrate binding domain, score 8e-30 216591020729 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.8e-19 216591020730 PS00044 Bacterial regulatory proteins, lysR family signature. 216591020731 Predicted helix-turn-helix motif with score 1156.000, SD 3.12 at aa 16-37, sequence GSVTGAGELLGRSQPAVTRQIQ 216591020732 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591020733 Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems; Region: PBP1_ABC_ligand_binding_like_14; cd06349 216591020734 putative ligand binding site [chemical binding]; other site 216591020735 HMMPfam hit to PF01094, Receptor family ligand binding region, score 1.3e-28 216591020736 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591020737 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 216591020738 TM-ABC transporter signature motif; other site 216591020739 ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177 216591020740 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 216591020741 TM-ABC transporter signature motif; other site 216591020742 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 9.5e-47 216591020743 15 probable transmembrane helices predicted for BCAM0611 by TMHMM2.0 at aa 13-35, 58-80, 93-115, 138-160, 193-215, 230-252, 257-279, 312-334, 341-363, 387-409, 416-438, 458-480, 509-531, 546-568 and 573-595 216591020744 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020745 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 9.2e-37 216591020746 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 216591020747 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 216591020748 Walker A/P-loop; other site 216591020749 ATP binding site [chemical binding]; other site 216591020750 Q-loop/lid; other site 216591020751 ABC transporter signature motif; other site 216591020752 Walker B; other site 216591020753 D-loop; other site 216591020754 H-loop/switch region; other site 216591020755 HMMPfam hit to PF00005, ABC transporter score 4.8e-53 216591020756 PS00017 ATP/GTP-binding site motif A (P-loop). 216591020757 PS00063 Aldo/keto reductase family putative active site signature. 216591020758 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 216591020759 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 216591020760 Walker A/P-loop; other site 216591020761 ATP binding site [chemical binding]; other site 216591020762 Q-loop/lid; other site 216591020763 ABC transporter signature motif; other site 216591020764 Walker B; other site 216591020765 D-loop; other site 216591020766 H-loop/switch region; other site 216591020767 HMMPfam hit to PF00005, ABC transporter score 3.2e-42 216591020768 PS00017 ATP/GTP-binding site motif A (P-loop). 216591020769 PS00211 ABC transporters family signature. 216591020770 DinB family; Region: DinB; cl17821 216591020771 DinB superfamily; Region: DinB_2; pfam12867 216591020772 HMMPfam hit to PF05163, DinB family, score 2.3e-06 216591020773 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591020774 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591020775 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 6.2e-15 216591020776 Predicted helix-turn-helix motif with score 1594.000, SD 4.62 at aa 44-65, sequence FTTNEVAQVAGVSIGSVYQYFP 216591020777 Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521 216591020778 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591020779 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304 216591020780 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591020781 dimer interface [polypeptide binding]; other site 216591020782 phosphorylation site [posttranslational modification] 216591020783 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591020784 ATP binding site [chemical binding]; other site 216591020785 Mg2+ binding site [ion binding]; other site 216591020786 G-X-G motif; other site 216591020787 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.4e-28 216591020788 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 4e-06 216591020789 HMMPfam hit to PF00672, HAMP domain, score 2.2e-06 216591020790 2 probable transmembrane helices predicted for BCAM0617 by TMHMM2.0 at aa 15-37 and 166-188 216591020791 HMMPfam hit to PF08521, Two-component sensor kinase N-terminal, score 4.1e-31 216591020792 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591020793 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591020794 active site 216591020795 phosphorylation site [posttranslational modification] 216591020796 intermolecular recognition site; other site 216591020797 dimerization interface [polypeptide binding]; other site 216591020798 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591020799 DNA binding site [nucleotide binding] 216591020800 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.6e-18 216591020801 HMMPfam hit to PF00072, Response regulator receiver domain, score 3.5e-35 216591020802 NMT1-like family; Region: NMT1_2; pfam13379 216591020803 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 216591020804 1 probable transmembrane helix predicted for BCAM0619 by TMHMM2.0 at aa 21-40 216591020805 PS00093 N-4 cytosine-specific DNA methylases signature. 216591020806 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591020807 D-galactonate transporter; Region: 2A0114; TIGR00893 216591020808 putative substrate translocation pore; other site 216591020809 12 probable transmembrane helices predicted for BCAM0620 by TMHMM2.0 at aa 21-38, 53-75, 88-110, 120-142, 149-171, 181-203, 249-271, 286-304, 311-333, 338-360, 365-387 and 402-424 216591020810 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.3e-46 216591020811 Histidine kinase; Region: HisKA_3; pfam07730 216591020812 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2.2e-15 216591020813 HMMPfam hit to PF07730, Histidine kinase, score 1.8e-13 216591020814 8 probable transmembrane helices predicted for BCAM0622 by TMHMM2.0 at aa 40-62, 72-94, 99-121, 141-163, 176-198, 213-232, 244-266 and 276-298 216591020815 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591020816 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591020817 active site 216591020818 phosphorylation site [posttranslational modification] 216591020819 intermolecular recognition site; other site 216591020820 dimerization interface [polypeptide binding]; other site 216591020821 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591020822 DNA binding residues [nucleotide binding] 216591020823 dimerization interface [polypeptide binding]; other site 216591020824 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 3.1e-18 216591020825 PS00622 Bacterial regulatory proteins, luxR family signature. 216591020826 HMMPfam hit to PF00072, Response regulator receiver domain, score 4.2e-31 216591020827 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 216591020828 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 216591020829 active site 216591020830 LssY C-terminus; Region: LssY_C; pfam14067 216591020831 12 probable transmembrane helices predicted for BCAM0625 by TMHMM2.0 at aa 5-27, 32-54, 59-81, 143-165, 175-197, 240-262, 296-318, 325-347, 362-384, 391-413, 417-439 and 452-471 216591020832 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020833 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020834 Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681 216591020835 Predicted helix-turn-helix motif with score 1409.000, SD 3.99 at aa 57-78, sequence GGLGAVAAEAGISRESLYRTLS 216591020836 putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683 216591020837 HMMPfam hit to PF05973, Phage derived protein Gp49-like (DUF891), score 4.3e-17 216591020838 Low molecular weight phosphatase family; Region: LMWPc; cd00115 216591020839 Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451 216591020840 active site 216591020841 HMMPfam hit to PF01451, Low molecular weight phosphotyrosine protein, score 6.4e-29 216591020842 Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072 216591020843 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738 216591020844 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 216591020845 HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 7.2e-60 216591020846 PS01174 Lipolytic enzymes G-D-X-G family, putative serine active site. 216591020847 1 probable transmembrane helix predicted for BCAM0629 by TMHMM2.0 at aa 12-34 216591020848 choline dehydrogenase; Validated; Region: PRK02106 216591020849 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 216591020850 HMMPfam hit to PF05199, GMC oxidoreductase, score 2.1e-62 216591020851 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.0015 216591020852 HMMPfam hit to PF00732, GMC oxidoreductase, score 1.2e-113 216591020853 PS00624 GMC oxidoreductases signature 2. 216591020854 PS00623 GMC oxidoreductases signature 1. 216591020855 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020856 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 216591020857 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591020858 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591020859 Predicted helix-turn-helix motif with score 1809.000, SD 5.35 at aa 252-273, sequence FSLEDMARLMNTSPRTLKRRLQ 216591020860 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 4.4e-10 216591020861 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 216591020862 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591020863 Coenzyme A binding pocket [chemical binding]; other site 216591020864 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 7.2e-13 216591020865 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591020866 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591020867 putative DNA binding site [nucleotide binding]; other site 216591020868 putative Zn2+ binding site [ion binding]; other site 216591020869 AsnC family; Region: AsnC_trans_reg; pfam01037 216591020870 HMMPfam hit to PF01037, AsnC family, score 5.7e-19 216591020871 PS00519 Bacterial regulatory proteins, asnC family signature. 216591020872 Predicted helix-turn-helix motif with score 1219.000, SD 3.34 at aa 23-44, sequence TPLSEVGRRIGLSQPATSERVK 216591020873 Predicted esterase of the alpha/beta hydrolase fold [General function prediction only]; Region: COG3545 216591020874 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591020875 HMMPfam hit to PF06821, Alpha/Beta hydrolase family of unknown funct, score 6.6e-58 216591020876 12 probable transmembrane helices predicted for BCAM0637 by TMHMM2.0 at aa 30-52, 67-89, 94-116, 126-148, 155-177, 187-209, 237-259, 269-291, 303-321, 326-348, 360-382 and 386-408 216591020877 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.9e-29 216591020878 HMMPfam hit to PF06779, Protein of unknown function (DUF1228), score 1.1e-18 216591020879 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020880 Flavin Reductases; Region: FlaRed; cl00801 216591020881 HMMPfam hit to PF01613, Flavin reductase like domain, score 1.3e-43 216591020882 Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566 216591020883 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591020884 active site 216591020885 phosphorylation site [posttranslational modification] 216591020886 intermolecular recognition site; other site 216591020887 dimerization interface [polypeptide binding]; other site 216591020888 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591020889 DNA binding residues [nucleotide binding] 216591020890 dimerization interface [polypeptide binding]; other site 216591020891 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.5e-27 216591020892 HMMPfam hit to PF08281, Sigma-70, region, score 6.7e-08 216591020893 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 9.7e-21 216591020894 PS00622 Bacterial regulatory proteins, luxR family signature. 216591020895 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557 216591020896 classical (c) SDRs; Region: SDR_c; cd05233 216591020897 NAD(P) binding site [chemical binding]; other site 216591020898 active site 216591020899 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.5e-20 216591020900 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 216591020901 PS00061 Short-chain dehydrogenases/reductases family signature. 216591020902 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154 216591020903 Amidase; Region: Amidase; cl11426 216591020904 HMMPfam hit to PF01425, Amidase, score 4.9e-60 216591020905 PS00571 Amidases signature. 216591020906 SnoaL-like domain; Region: SnoaL_4; pfam13577 216591020907 PS00513 Adenylosuccinate synthetase active site. 216591020908 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591020909 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591020910 active site 216591020911 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 1.7e-27 216591020912 PAS domain; Region: PAS_9; pfam13426 216591020913 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 216591020914 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591020915 putative active site [active] 216591020916 heme pocket [chemical binding]; other site 216591020917 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591020918 dimer interface [polypeptide binding]; other site 216591020919 phosphorylation site [posttranslational modification] 216591020920 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591020921 ATP binding site [chemical binding]; other site 216591020922 Mg2+ binding site [ion binding]; other site 216591020923 G-X-G motif; other site 216591020924 HMMPfam hit to PF00989, PAS fold, score 0.074 216591020925 HMMPfam hit to PF00989, PAS fold, score 9.2e-05 216591020926 HMMPfam hit to PF08447, PAS fold, score 0.0016 216591020927 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.00085 216591020928 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.4e-20 216591020929 4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235 216591020930 active site 1 [active] 216591020931 dimer interface [polypeptide binding]; other site 216591020932 hexamer interface [polypeptide binding]; other site 216591020933 active site 2 [active] 216591020934 4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235 216591020935 active site 1 [active] 216591020936 dimer interface [polypeptide binding]; other site 216591020937 hexamer interface [polypeptide binding]; other site 216591020938 active site 2 [active] 216591020939 HMMPfam hit to PF01361, Tautomerase enzyme, score 1.1e-12 216591020940 HMMPfam hit to PF01361, Tautomerase enzyme, score 8.5e-15 216591020941 Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109 216591020942 HMMPfam hit to PF00866, Ring hydroxylating beta subunit, score 2.4e-18 216591020943 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 216591020944 Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469 216591020945 [2Fe-2S] cluster binding site [ion binding]; other site 216591020946 C-terminal catalytic domain of the oxygenase alpha subunit of Pseudomonas resinovorans strain CA10 anthranilate 1,2-dioxygenase and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_AntDO-like; cd08879 216591020947 putative alpha subunit interface [polypeptide binding]; other site 216591020948 putative active site [active] 216591020949 putative substrate binding site [chemical binding]; other site 216591020950 Fe binding site [ion binding]; other site 216591020951 HMMPfam hit to PF00848, Ring hydroxylating alpha subunit (cat, score 3.2e-11 216591020952 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 2.9e-34 216591020953 PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 216591020954 leucine transcriptional activator; Reviewed; Region: leuO; PRK09508 216591020955 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020956 The C-terminal substrate binding domain of LysR-type transcriptional regulators that are involved in the catabolism of dinitrotoluene, naphthalene and gamma-hexachlorohexane; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_NahR_LinR_like; cd08459 216591020957 substrate binding pocket [chemical binding]; other site 216591020958 dimerization interface [polypeptide binding]; other site 216591020959 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.2e-21 216591020960 Predicted helix-turn-helix motif with score 1349.000, SD 3.78 at aa 27-48, sequence RSLTKAGERLALSQPAVSYSLG 216591020961 PS00044 Bacterial regulatory proteins, lysR family signature. 216591020962 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.4e-21 216591020963 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018 216591020964 Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185 216591020965 FMN-binding pocket [chemical binding]; other site 216591020966 flavin binding motif; other site 216591020967 phosphate binding motif [ion binding]; other site 216591020968 beta-alpha-beta structure motif; other site 216591020969 NAD binding pocket [chemical binding]; other site 216591020970 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591020971 catalytic loop [active] 216591020972 iron binding site [ion binding]; other site 216591020973 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 1.2e-17 216591020974 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591020975 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 8.7e-06 216591020976 1 probable transmembrane helix predicted for BCAM0650 by TMHMM2.0 at aa 112-131 216591020977 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 1.9e-06 216591020978 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591020979 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591020980 putative substrate translocation pore; other site 216591020981 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020982 12 probable transmembrane helices predicted for BCAM0651 by TMHMM2.0 at aa 20-42, 57-79, 86-108, 112-134, 146-168, 188-210, 249-271, 281-303, 315-337, 342-364, 377-399 and 414-433 216591020983 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.8e-49 216591020984 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020985 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591020986 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591020987 trimer interface [polypeptide binding]; other site 216591020988 eyelet of channel; other site 216591020989 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591020990 1 probable transmembrane helix predicted for BCAM0652 by TMHMM2.0 at aa 13-35 216591020991 HMMPfam hit to PF00267, Gram-negative porin, score 0.00026 216591020992 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591020993 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591020994 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591020995 dimerization interface [polypeptide binding]; other site 216591020996 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-15 216591020997 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.1e-20 216591020998 PS00044 Bacterial regulatory proteins, lysR family signature. 216591020999 Predicted helix-turn-helix motif with score 1305.000, SD 3.63 at aa 48-69, sequence RHVGRAALRLGVTQPSVSYALG 216591021000 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591021001 PS00041 Bacterial regulatory proteins, araC family signature. 216591021002 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00091 216591021003 Predicted helix-turn-helix motif with score 1233.000, SD 3.39 at aa 235-256, sequence LALAALAAVAGVAPRTLQHAFR 216591021004 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210 216591021005 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain; Region: Octopine_DH; pfam02317 216591021006 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 3.8e-05 216591021007 HMMPfam hit to PF02317, NAD/NADP octopine/nopaline dehydrogena, score 7.4e-62 216591021008 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 216591021009 3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK08269 216591021010 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 216591021011 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD binding, score 2.4e-51 216591021012 1 probable transmembrane helix predicted for BCAM0656 by TMHMM2.0 at aa 7-29 216591021013 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 1.3e-19 216591021014 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591021015 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591021016 putative substrate translocation pore; other site 216591021017 HMMPfam hit to PF00083, Sugar (and other) transporter score 4.3e-19 216591021018 12 probable transmembrane helices predicted for BCAM0657 by TMHMM2.0 at aa 40-57, 67-86, 99-121, 131-153, 165-187, 197-217, 255-277, 287-309, 316-335, 345-367, 380-402 and 407-429 216591021019 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.5e-22 216591021020 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021021 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591021022 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591021023 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591021024 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.7e-30 216591021025 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021026 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.5e-24 216591021027 PS00044 Bacterial regulatory proteins, lysR family signature. 216591021028 Predicted helix-turn-helix motif with score 1775.000, SD 5.23 at aa 16-37, sequence GSIGKAADALGLSQPALTKAVQ 216591021029 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06187 216591021030 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591021031 Bacterial Bile acid CoA ligases and similar proteins; Region: BACL_like; cd05929 216591021032 acyl-activating enzyme (AAE) consensus motif; other site 216591021033 putative AMP binding site [chemical binding]; other site 216591021034 putative active site [active] 216591021035 putative CoA binding site [chemical binding]; other site 216591021036 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.3e-113 216591021037 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591021038 PS00455 Putative AMP-binding domain signature. 216591021039 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591021040 Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771 216591021041 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 216591021042 active site 216591021043 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 5.5e-26 216591021044 PS00072 Acyl-CoA dehydrogenases signature 1. 216591021045 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 4.4e-53 216591021046 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 1.4e-13 216591021047 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591021048 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591021049 HMMPfam hit to PF02515, CoA-transferase family III, score 1.1e-41 216591021050 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591021051 D-galactonate transporter; Region: 2A0114; TIGR00893 216591021052 putative substrate translocation pore; other site 216591021053 11 probable transmembrane helices predicted for BCAM0662 by TMHMM2.0 at aa 15-37, 50-72, 82-104, 140-162, 167-189, 216-238, 253-275, 288-308, 318-340, 352-374 and 384-406 216591021054 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1e-45 216591021055 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021056 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021057 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591021058 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591021059 trimer interface [polypeptide binding]; other site 216591021060 eyelet of channel; other site 216591021061 HMMPfam hit to PF00267, Gram-negative porin, score 0.00051 216591021062 BON domain; Region: BON; pfam04972 216591021063 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 1e-09 216591021064 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 216591021065 Beta-lactamase; Region: Beta-lactamase; pfam00144 216591021066 1 probable transmembrane helix predicted for BCAM0665 by TMHMM2.0 at aa 13-35 216591021067 HMMPfam hit to PF00144, Beta-lactamase, score 2.5e-18 216591021068 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 216591021069 Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416 216591021070 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 6.1e-14 216591021071 C-terminus matches Burkholderia cenocepacia HI2424 transposase, is605 orfb. UniProt:Q4LL61 (EMBL:AAHL01000053) (350 aa) fasta scores: E()=2.7e-25, 75.758% id in 99 aa; N terminus matches Burkholderia cenocepacia HI2424 transposase, is605 orfb. UniProt:Q4LL61 (EMBL:AAHL01000053) (350 aa) fasta scores: E()=2.7e-25, 75.758% id in 99 aa, and to Burkholderia cenocepacia HI2424 transposase, is605 orfb. UniProt:Q4LSK6 (EMBL:AAHL01000020) (194 aa) fasta scores: E()=3.1e-28, 54.268% id in 164 aa; Contains nonsense codon after codon 85, and frameshift after codon 146 216591021072 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591021073 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 5.3e-88 216591021074 1 probable transmembrane helix predicted for BCAM0667 by TMHMM2.0 at aa 7-26 216591021075 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992 216591021076 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591021077 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 216591021078 HMMPfam hit to PF04324, BFD-like [2Fe-2S] binding domain, score 3.3e-18 216591021079 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 8.4e-11 216591021080 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510 216591021081 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 216591021082 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591021083 dimer interface [polypeptide binding]; other site 216591021084 conserved gate region; other site 216591021085 putative PBP binding loops; other site 216591021086 ABC-ATPase subunit interface; other site 216591021087 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1e-09 216591021088 6 probable transmembrane helices predicted for BCAM0670 by TMHMM2.0 at aa 7-29, 68-90, 97-119, 134-156, 177-199 and 228-250 216591021089 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591021090 ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178 216591021091 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591021092 dimer interface [polypeptide binding]; other site 216591021093 conserved gate region; other site 216591021094 putative PBP binding loops; other site 216591021095 ABC-ATPase subunit interface; other site 216591021096 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.4e-11 216591021097 6 probable transmembrane helices predicted for BCAM0671 by TMHMM2.0 at aa 24-46, 87-109, 116-138, 165-187, 223-245 and 267-289 216591021098 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 216591021099 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591021100 Walker A/P-loop; other site 216591021101 ATP binding site [chemical binding]; other site 216591021102 Q-loop/lid; other site 216591021103 ABC transporter signature motif; other site 216591021104 Walker B; other site 216591021105 D-loop; other site 216591021106 H-loop/switch region; other site 216591021107 TOBE domain; Region: TOBE_2; pfam08402 216591021108 HMMPfam hit to PF08402, TOBE domain, score 4.2e-18 216591021109 HMMPfam hit to PF03459, TOBE domain, score 0.00089 216591021110 HMMPfam hit to PF03459, TOBE domain, score 6e-05 216591021111 HMMPfam hit to PF00005, ABC transporter score 1.7e-66 216591021112 PS00211 ABC transporters family signature. 216591021113 PS00017 ATP/GTP-binding site motif A (P-loop). 216591021114 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591021115 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591021116 putative DNA binding site [nucleotide binding]; other site 216591021117 putative Zn2+ binding site [ion binding]; other site 216591021118 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591021119 Predicted helix-turn-helix motif with score 1612.000, SD 4.68 at aa 58-79, sequence VRVTHLAKAVGLTQGTAHRILQ 216591021120 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 2.1e-07 216591021121 short chain dehydrogenase; Provisional; Region: PRK06500 216591021122 classical (c) SDRs; Region: SDR_c; cd05233 216591021123 NAD(P) binding site [chemical binding]; other site 216591021124 active site 216591021125 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.2e-19 216591021126 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0021 216591021127 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 216591021128 Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139 216591021129 conserved cys residue [active] 216591021130 HMMPfam hit to PF01965, DJ-1/PfpI family, score 1.7e-10 216591021131 Ketosteroid isomerase homolog [Function unknown]; Region: COG4319 216591021132 SnoaL-like domain; Region: SnoaL_3; pfam13474 216591021133 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021134 1 probable transmembrane helix predicted for BCAM0676 by TMHMM2.0 at aa 7-29 216591021135 HMMPfam hit to PF02136, Nuclear transport factor 2 (NTF2) domain, score 0.0057 216591021136 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591021137 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 216591021138 conserved cys residue [active] 216591021139 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591021140 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 0.0013 216591021141 Predicted helix-turn-helix motif with score 1105.000, SD 2.95 at aa 225-246, sequence LPVERLADAASLSVRQFGRAFR 216591021142 HMMPfam hit to PF01965, DJ-1/PfpI family, score 8.4e-10 216591021143 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591021144 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.3e-15 216591021145 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591021146 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591021147 salt bridge; other site 216591021148 non-specific DNA binding site [nucleotide binding]; other site 216591021149 sequence-specific DNA binding site [nucleotide binding]; other site 216591021150 Predicted helix-turn-helix motif with score 1409.000, SD 3.99 at aa 37-58, sequence LRREEVAQRAHVSVAWYTWLEQ 216591021151 atypical (a) SDRs, subgroup 7; Region: SDR_a7; cd05262 216591021152 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 216591021153 putative NAD(P) binding site [chemical binding]; other site 216591021154 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 2.1e-06 216591021155 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 9.4e-07 216591021156 HMMPfam hit to PF07993, Male sterility protein, score 0.0023 216591021157 Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR2; cd08268 216591021158 NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604 216591021159 putative NAD(P) binding site [chemical binding]; other site 216591021160 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.2e-24 216591021161 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 5.7e-18 216591021162 transcriptional regulator; Provisional; Region: PRK10632 216591021163 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591021164 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472 216591021165 putative effector binding pocket; other site 216591021166 putative dimerization interface [polypeptide binding]; other site 216591021167 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.7e-40 216591021168 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.7e-17 216591021169 Predicted helix-turn-helix motif with score 1360.000, SD 3.82 at aa 17-38, sequence GNFTQAADALQLHRPAVTKAVQ 216591021170 mercuric reductase; Validated; Region: PRK06370 216591021171 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591021172 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 216591021173 HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 1e-26 216591021174 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 2e-45 216591021175 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 9.9e-27 216591021176 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 216591021177 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 216591021178 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591021179 Coenzyme A binding pocket [chemical binding]; other site 216591021180 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 9.6e-19 216591021181 LysE type translocator; Region: LysE; cl00565 216591021182 4 probable transmembrane helices predicted for BCAM0687 by TMHMM2.0 at aa 7-29, 44-66, 73-95 and 151-173 216591021183 HMMPfam hit to PF01810, LysE type translocator, score 2.5e-31 216591021184 Protein of unknown function (DUF3348); Region: DUF3348; pfam11828 216591021185 Domain of unknown function (DUF802); Region: DUF802; pfam05650 216591021186 Domain of unknown function (DUF802); Region: DUF802; pfam05650 216591021187 3 probable transmembrane helices predicted for BCAM0689 by TMHMM2.0 at aa 7-26, 31-53 and 107-129 216591021188 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021189 HMMPfam hit to PF05650, Domain of unknown function (DUF802), score 1.3e-16 216591021190 HMMPfam hit to PF05650, Domain of unknown function (DUF802), score 3.1e-11 216591021191 hypothetical protein; Provisional; Region: PRK09040 216591021192 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591021193 ligand binding site [chemical binding]; other site 216591021194 1 probable transmembrane helix predicted for BCAM0690 by TMHMM2.0 at aa 15-37 216591021195 HMMPfam hit to PF00691, OmpA family, score 8.5e-19 216591021196 Protein of unknown function (DUF2894); Region: DUF2894; pfam11445 216591021197 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591021198 Predicted flavoprotein [General function prediction only]; Region: COG0431 216591021199 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 5.3e-20 216591021200 8 probable transmembrane helices predicted for BCAM0694 by TMHMM2.0 at aa 21-38, 51-73, 93-115, 125-147, 222-244, 259-281, 301-323 and 364-386 216591021201 HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.5e-05 216591021202 HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.5e-05 216591021203 HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.5e-05 216591021204 HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 7.2e-06 216591021205 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021206 Carboxymuconolactone decarboxylase family; Region: CMD; cl00460 216591021207 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 3.6e-25 216591021208 Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303 216591021209 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591021210 catalytic site [active] 216591021211 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.7e-15 216591021212 1 probable transmembrane helix predicted for BCAM0697 by TMHMM2.0 at aa 7-29 216591021213 Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072 216591021214 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738 216591021215 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00034 216591021216 glucose-1-dehydrogenase; Provisional; Region: PRK06947 216591021217 classical (c) SDRs; Region: SDR_c; cd05233 216591021218 NAD(P) binding site [chemical binding]; other site 216591021219 active site 216591021220 HMMPfam hit to PF00106, short chain dehydrogenase, score 7.7e-23 216591021221 PS00061 Short-chain dehydrogenases/reductases family signature. 216591021222 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591021223 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591021224 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 5.8e-06 216591021225 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021226 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591021227 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591021228 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591021229 putative effector binding pocket; other site 216591021230 dimerization interface [polypeptide binding]; other site 216591021231 HMMPfam hit to PF03466, LysR substrate binding domain, score 4e-47 216591021232 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021233 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.1e-18 216591021234 PS00044 Bacterial regulatory proteins, lysR family signature. 216591021235 Predicted helix-turn-helix motif with score 1221.000, SD 3.35 at aa 22-43, sequence GSLTAAAERLGLAKTVVSTHMQ 216591021236 GST_N family, unknown subfamily 4; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_4; cd03056 216591021237 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591021238 putative C-terminal domain interface [polypeptide binding]; other site 216591021239 putative GSH binding site (G-site) [chemical binding]; other site 216591021240 putative dimer interface [polypeptide binding]; other site 216591021241 C-terminal, alpha helical domain of an unknown subfamily 7 of Glutathione S-transferases; Region: GST_C_7; cd03206 216591021242 putative N-terminal domain interface [polypeptide binding]; other site 216591021243 putative dimer interface [polypeptide binding]; other site 216591021244 putative substrate binding pocket (H-site) [chemical binding]; other site 216591021245 Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381 216591021246 Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381 216591021247 FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184 216591021248 phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160 216591021249 FAD binding pocket [chemical binding]; other site 216591021250 FAD binding motif [chemical binding]; other site 216591021251 phosphate binding motif [ion binding]; other site 216591021252 beta-alpha-beta structure motif; other site 216591021253 NAD binding pocket [chemical binding]; other site 216591021254 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591021255 catalytic loop [active] 216591021256 iron binding site [ion binding]; other site 216591021257 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591021258 Protein of unknown function (DUF2970); Region: DUF2970; pfam11174 216591021259 PS00044 Bacterial regulatory proteins, lysR family signature. 216591021260 1 probable transmembrane helix predicted for BCAM0705 by TMHMM2.0 at aa 32-54 216591021261 CDS contains a frameshift after codon 66. Similar to Burkholderia cenocepacia TonB-dependent siderophore receptor precursor UniProt:Q1BLD6 (EMBL:CP000379 (743 aa) fasta scores: E()=0, 97.443% id in 743 aa 216591021262 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.1e-08 216591021263 HMMPfam hit to PF00593, TonB dependent receptor, score 8.4e-27 216591021264 PS01156 TonB-dependent receptor proteins signature 2. 216591021265 Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973 216591021266 HMMPfam hit to PF04973, Nicotinamide mononucleotide transport, score 1.5e-18 216591021267 5 probable transmembrane helices predicted for BCAM0707 by TMHMM2.0 at aa 4-18, 25-42, 120-139, 144-163 and 167-186 216591021268 Phosphotransferase enzyme family; Region: APH; pfam01636 216591021269 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270 216591021270 active site 216591021271 ATP binding site [chemical binding]; other site 216591021272 substrate binding site [chemical binding]; other site 216591021273 HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 8.4e-18 216591021274 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931 216591021275 Peptidase M35 family; Region: M35_like; cd11005 216591021276 active site 216591021277 Zn binding site [ion binding]; other site 216591021278 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591021279 type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844 216591021280 PS00216 Sugar transport proteins signature 1. 216591021281 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591021282 Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999 216591021283 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591021284 1 probable transmembrane helix predicted for BCAM0712 by TMHMM2.0 at aa 7-26 216591021285 heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914 216591021286 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 216591021287 11 probable transmembrane helices predicted for BCAM0713 by TMHMM2.0 at aa 10-29, 353-375, 395-414, 451-470, 485-507, 540-559, 889-906, 913-935, 939-961, 985-1007 and 1017-1039 216591021288 heavy metal response regulator; Region: cztR_silR_copR; TIGR01387 216591021289 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591021290 active site 216591021291 phosphorylation site [posttranslational modification] 216591021292 intermolecular recognition site; other site 216591021293 dimerization interface [polypeptide binding]; other site 216591021294 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591021295 DNA binding site [nucleotide binding] 216591021296 HMMPfam hit to PF00072, Response regulator receiver domain, score 3.3e-37 216591021297 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 2.9e-23 216591021298 heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386 216591021299 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591021300 dimerization interface [polypeptide binding]; other site 216591021301 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591021302 dimer interface [polypeptide binding]; other site 216591021303 phosphorylation site [posttranslational modification] 216591021304 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591021305 ATP binding site [chemical binding]; other site 216591021306 Mg2+ binding site [ion binding]; other site 216591021307 G-X-G motif; other site 216591021308 2 probable transmembrane helices predicted for BCAM0715 by TMHMM2.0 at aa 15-37 and 168-190 216591021309 HMMPfam hit to PF00672, HAMP domain, score 7.8e-12 216591021310 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 8.6e-18 216591021311 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 7e-42 216591021312 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591021313 1 probable transmembrane helix predicted for BCAM0716 by TMHMM2.0 at aa 7-26 216591021314 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591021315 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591021316 trimer interface [polypeptide binding]; other site 216591021317 eyelet of channel; other site 216591021318 HMMPfam hit to PF00267, Gram-negative porin, score 1.5e-06 216591021319 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591021320 1 probable transmembrane helix predicted for BCAM0719 by TMHMM2.0 at aa 7-24 216591021321 8 probable transmembrane helices predicted for BCAM0720 by TMHMM2.0 at aa 7-27, 37-56, 61-83, 98-120, 127-149, 153-175, 182-204 and 219-238 216591021322 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021323 O-acetylhomoserine aminocarboxypropyltransferase; Validated; Region: PRK06084 216591021324 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 216591021325 homodimer interface [polypeptide binding]; other site 216591021326 substrate-cofactor binding pocket; other site 216591021327 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591021328 catalytic residue [active] 216591021329 Methyltransferase domain; Region: Methyltransf_31; pfam13847 216591021330 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591021331 S-adenosylmethionine binding site [chemical binding]; other site 216591021332 HMMPfam hit to PF01596, O-methyltransferase, score 7.1e-18 216591021333 PS00213 Lipocalin signature. 216591021334 1 probable transmembrane helix predicted for BCAM0723 by TMHMM2.0 at aa 21-43 216591021335 Protein of unknown function (DUF1176); Region: DUF1176; pfam06674 216591021336 HMMPfam hit to PF06674, Protein of unknown function (DUF1176), score 1e-10 216591021337 Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127 216591021338 Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139 216591021339 hypothetical protein; Reviewed; Region: PRK09588 216591021340 HMMPfam hit to PF01139, Uncharacterized protein family UPF0027, score 4.1e-187 216591021341 PS01288 Uncharacterized protein family UPF0027 signature. 216591021342 Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330 216591021343 Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403 216591021344 HMMPfam hit to PF01145, SPFH domain / Band, score 2.2e-16 216591021345 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650 216591021346 Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956 216591021347 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591021348 Walker A motif; other site 216591021349 ATP binding site [chemical binding]; other site 216591021350 Walker B motif; other site 216591021351 arginine finger; other site 216591021352 HMMPfam hit to PF06956, Regulator of RNA terminal phosphate c, score 7.4e-109 216591021353 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3.2e-59 216591021354 HMMPfam hit to PF07728, ATPase family associated with various, score 7.4e-05 216591021355 PS00017 ATP/GTP-binding site motif A (P-loop). 216591021356 SUKH-3 immunity protein; Region: SUKH-3; pfam14433 216591021357 SnoaL-like domain; Region: SnoaL_4; cl17707 216591021358 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591021359 MarR family; Region: MarR_2; pfam12802 216591021360 HMMPfam hit to PF01047, MarR family, score 0.00022 216591021361 cysteine desulfurase; Provisional; Region: PRK14012 216591021362 cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402 216591021363 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591021364 catalytic residue [active] 216591021365 HMMPfam hit to PF00266, Aminotransferase class-V, score 8.2e-123 216591021366 HMMPfam hit to PF01212, Beta-eliminating lyase, score 1.8e-06 216591021367 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 216591021368 Flavin reductase like domain; Region: Flavin_Reduct; smart00903 216591021369 HMMPfam hit to PF01613, Flavin reductase like domain, score 1.5e-39 216591021370 4-hydroxyphenylacetate 3-hydroxylase N terminal; Region: HpaB_N; pfam11794 216591021371 4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241 216591021372 HMMPfam hit to PF03241, 4-hydroxyphenylacetate 3-hydroxylase family, score 2.5e-93 216591021373 Protein of unknown function (DUF2848); Region: DUF2848; pfam11010 216591021374 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591021375 S-adenosylmethionine binding site [chemical binding]; other site 216591021376 HMMPfam hit to PF08241, Methyltransferase domain, score 3.3e-18 216591021377 HMMPfam hit to PF08242, Methyltransferase domain, score 9.3e-25 216591021378 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591021379 HMMPfam hit to PF01810, LysE type translocator, score 1.6e-31 216591021380 5 probable transmembrane helices predicted for BCAM0738 by TMHMM2.0 at aa 7-29, 44-66, 71-93, 149-171 and 183-205 216591021381 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021382 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 216591021383 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591021384 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 216591021385 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591021386 PS00228 Tubulin-beta mRNA autoregulation signal. 216591021387 HMMPfam hit to PF02311, AraC-like ligand binding domain, score 1.9e-07 216591021388 HMMPfam hit to PF07883, Cupin domain, score 0.00035 216591021389 PS00041 Bacterial regulatory proteins, araC family signature. 216591021390 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 0.00069 216591021391 Predicted helix-turn-helix motif with score 1175.000, SD 3.19 at aa 180-201, sequence SPLPELARRAGISERSLTRLAT 216591021392 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 3.7e-06 216591021393 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591021394 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591021395 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472 216591021396 putative effector binding pocket; other site 216591021397 putative dimerization interface [polypeptide binding]; other site 216591021398 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.8e-18 216591021399 Predicted helix-turn-helix motif with score 1419.000, SD 4.02 at aa 18-39, sequence NSFTRAAQALGISRATATRTVQ 216591021400 PS00044 Bacterial regulatory proteins, lysR family signature. 216591021401 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.9e-27 216591021402 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591021403 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479 216591021404 putative effector binding pocket; other site 216591021405 putative dimerization interface [polypeptide binding]; other site 216591021406 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.3e-47 216591021407 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.4e-17 216591021408 PS00044 Bacterial regulatory proteins, lysR family signature. 216591021409 Predicted helix-turn-helix motif with score 1506.000, SD 4.32 at aa 20-41, sequence GSLSAAARELGLTAAAVSKRLT 216591021410 Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473 216591021411 tartrate dehydrogenase; Region: TTC; TIGR02089 216591021412 HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase, score 1.9e-91 216591021413 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591021414 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591021415 putative substrate translocation pore; other site 216591021416 12 probable transmembrane helices predicted for BCAM0744 by TMHMM2.0 at aa 13-30, 45-67, 87-109, 114-133, 140-162, 172-194, 244-266, 276-298, 310-327, 331-353, 360-382 and 397-419 216591021417 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.4e-46 216591021418 Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190 216591021419 active site 216591021420 PS00017 ATP/GTP-binding site motif A (P-loop). 216591021421 argininosuccinate synthase; Validated; Region: PRK05370 216591021422 argininosuccinate synthase; Provisional; Region: PRK13820 216591021423 HMMPfam hit to PF00764, Arginosuccinate synthase, score 7.5e-183 216591021424 PS00565 Argininosuccinate synthase signature 2. 216591021425 PS00564 Argininosuccinate synthase signature 1. 216591021426 Predicted membrane protein [Function unknown]; Region: COG1289 216591021427 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 216591021428 4 probable transmembrane helices predicted for BCAM0747 by TMHMM2.0 at aa 33-55, 92-114, 121-143 and 158-180 216591021429 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021430 Cache domain; Region: Cache_1; pfam02743 216591021431 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591021432 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591021433 metal binding site [ion binding]; metal-binding site 216591021434 active site 216591021435 I-site; other site 216591021436 HMMPfam hit to PF00990, GGDEF domain, score 8.3e-67 216591021437 2 probable transmembrane helices predicted for BCAM0748 by TMHMM2.0 at aa 21-43 and 301-323 216591021438 lysine transporter; Provisional; Region: PRK10836 216591021439 HMMPfam hit to PF00324, Amino acid permease, score 2.1e-174 216591021440 12 probable transmembrane helices predicted for BCAM0749 by TMHMM2.0 at aa 27-49, 59-81, 109-131, 136-158, 165-187, 202-224, 251-273, 296-318, 353-372, 376-398, 422-441 and 451-473 216591021441 PS00218 Amino acid permeases signature. 216591021442 Protein of unknown function (DUF3717); Region: DUF3717; pfam12512 216591021443 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 216591021444 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591021445 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in benzoate catabolism; contains the type 2 periplasmic binding fold; Region: PBP2_BenM_CatM_CatR; cd08445 216591021446 dimerizarion interface [polypeptide binding]; other site 216591021447 CrgA pocket; other site 216591021448 substrate binding pocket [chemical binding]; other site 216591021449 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.3e-25 216591021450 Predicted helix-turn-helix motif with score 1599.000, SD 4.63 at aa 16-37, sequence RNFTRAAERLHIAQPPLSRQIQ 216591021451 PS00044 Bacterial regulatory proteins, lysR family signature. 216591021452 HMMPfam hit to PF03466, LysR substrate binding domain, score 7.3e-42 216591021453 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591021454 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1e-13 216591021455 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021456 3 probable transmembrane helices predicted for BCAM0753 by TMHMM2.0 at aa 20-39, 59-81 and 93-115 216591021457 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591021458 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591021459 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 5.2e-15 216591021460 PS01081 Bacterial regulatory proteins, tetR family signature. 216591021461 Predicted helix-turn-helix motif with score 1629.000, SD 4.74 at aa 38-59, sequence VTMEQIAAQADVAKRTLYNHFP 216591021462 This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784 216591021463 homodimer interface [polypeptide binding]; other site 216591021464 active site 216591021465 TDP-binding site; other site 216591021466 acceptor substrate-binding pocket; other site 216591021467 HMMPfam hit to PF03033, Glycosyltransferase family, score 2e-08 216591021468 histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018 216591021469 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591021470 DNA-binding site [nucleotide binding]; DNA binding site 216591021471 UTRA domain; Region: UTRA; pfam07702 216591021472 HMMPfam hit to PF07702, UTRA domain, score 4.1e-40 216591021473 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 3.2e-23 216591021474 Predicted helix-turn-helix motif with score 1487.000, SD 4.25 at aa 29-50, sequence PSENELAREFNVARMTVNRALR 216591021475 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591021476 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591021477 trimer interface [polypeptide binding]; other site 216591021478 eyelet of channel; other site 216591021479 HMMPfam hit to PF00267, Gram-negative porin, score 6.2e-06 216591021480 histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437 216591021481 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591021482 substrate binding pocket [chemical binding]; other site 216591021483 membrane-bound complex binding site; other site 216591021484 hinge residues; other site 216591021485 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.8e-91 216591021486 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591021487 PS00017 ATP/GTP-binding site motif A (P-loop). 216591021488 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591021489 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591021490 dimer interface [polypeptide binding]; other site 216591021491 conserved gate region; other site 216591021492 putative PBP binding loops; other site 216591021493 ABC-ATPase subunit interface; other site 216591021494 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.9e-30 216591021495 5 probable transmembrane helices predicted for BCAM0760 by TMHMM2.0 at aa 20-42, 55-77, 92-109, 156-178 and 191-213 216591021496 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591021497 PS00017 ATP/GTP-binding site motif A (P-loop). 216591021498 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591021499 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591021500 dimer interface [polypeptide binding]; other site 216591021501 conserved gate region; other site 216591021502 putative PBP binding loops; other site 216591021503 ABC-ATPase subunit interface; other site 216591021504 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.3e-12 216591021505 3 probable transmembrane helices predicted for BCAM0761 by TMHMM2.0 at aa 20-42, 63-85 and 199-221 216591021506 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591021507 ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; Region: HisP; COG4598 216591021508 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 216591021509 Walker A/P-loop; other site 216591021510 ATP binding site [chemical binding]; other site 216591021511 Q-loop/lid; other site 216591021512 ABC transporter signature motif; other site 216591021513 Walker B; other site 216591021514 D-loop; other site 216591021515 H-loop/switch region; other site 216591021516 HMMPfam hit to PF00005, ABC transporter score 1.6e-67 216591021517 PS00017 ATP/GTP-binding site motif A (P-loop). 216591021518 PS00211 ABC transporters family signature. 216591021519 Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439 216591021520 domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758 216591021521 HMMPfam hit to PF07691, PA14 domain, score 1.6e-24 216591021522 PS00017 ATP/GTP-binding site motif A (P-loop). 216591021523 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021524 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591021525 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591021526 DNA binding site [nucleotide binding] 216591021527 Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288 216591021528 putative dimerization interface [polypeptide binding]; other site 216591021529 putative ligand binding site [chemical binding]; other site 216591021530 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 4.3e-09 216591021531 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 8.7e-07 216591021532 PS00356 Bacterial regulatory proteins, lacI family signature. 216591021533 aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021 216591021534 active site 216591021535 catalytic residues [active] 216591021536 HMMPfam hit to PF01263, Aldose 1-epimerase, score 2.4e-43 216591021537 Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309 216591021538 putative ligand binding site [chemical binding]; other site 216591021539 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 216591021540 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021541 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 5.1e-07 216591021542 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 216591021543 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 216591021544 Walker A/P-loop; other site 216591021545 ATP binding site [chemical binding]; other site 216591021546 Q-loop/lid; other site 216591021547 ABC transporter signature motif; other site 216591021548 Walker B; other site 216591021549 D-loop; other site 216591021550 H-loop/switch region; other site 216591021551 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 216591021552 HMMPfam hit to PF00005, ABC transporter score 6.4e-54 216591021553 PS00017 ATP/GTP-binding site motif A (P-loop). 216591021554 HMMPfam hit to PF00005, ABC transporter score 6.2e-25 216591021555 PS00211 ABC transporters family signature. 216591021556 Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454 216591021557 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591021558 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591021559 TM-ABC transporter signature motif; other site 216591021560 9 probable transmembrane helices predicted for BCAM0768 by TMHMM2.0 at aa 29-48, 58-75, 82-99, 103-125, 132-151, 171-193, 224-246, 266-288 and 301-320 216591021561 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 7e-60 216591021562 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591021563 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591021564 TM-ABC transporter signature motif; other site 216591021565 8 probable transmembrane helices predicted for BCAM0769 by TMHMM2.0 at aa 25-46, 56-78, 83-100, 104-126, 133-152, 172-194, 266-288 and 303-325 216591021566 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 4.2e-57 216591021567 Cupin domain; Region: Cupin_2; cl17218 216591021568 HMMPfam hit to PF07883, Cupin domain, score 1.2e-05 216591021569 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591021570 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591021571 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591021572 HMMPfam hit to PF01548, Transposase, score 0.001 216591021573 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 1.1e-39 216591021574 Protein of unknown function (DUF3761); Region: DUF3761; pfam12587 216591021575 1 probable transmembrane helix predicted for BCAM0773 by TMHMM2.0 at aa 5-27 216591021576 polyhydroxyalkanoate depolymerase, intracellular; Region: PHB_depoly_PhaZ; TIGR01849 216591021577 PHB de-polymerase C-terminus; Region: PHB_depo_C; pfam06850 216591021578 HMMPfam hit to PF06850, PHB de-polymerase C-terminus, score 2e-115 216591021579 GST_N family, unknown subfamily 1; composed of uncharacterized proteins, predominantly from bacteria, with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with...; Region: GST_N_1; cd03043 216591021580 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591021581 putative C-terminal domain interface [polypeptide binding]; other site 216591021582 putative GSH binding site (G-site) [chemical binding]; other site 216591021583 putative dimer interface [polypeptide binding]; other site 216591021584 C-terminal, alpha helical domain of an unknown subfamily 3 of Glutathione S-transferases; Region: GST_C_3; cd03194 216591021585 putative N-terminal domain interface [polypeptide binding]; other site 216591021586 putative dimer interface [polypeptide binding]; other site 216591021587 putative substrate binding pocket (H-site) [chemical binding]; other site 216591021588 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 0.0037 216591021589 Predicted helix-turn-helix motif with score 997.000, SD 2.58 at aa 21-42, sequence MRGWLLAKLSGLTFETISVPID 216591021590 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 216591021591 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 216591021592 ligand binding site [chemical binding]; other site 216591021593 flexible hinge region; other site 216591021594 HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 1.5e-15 216591021595 MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568 216591021596 4 probable transmembrane helices predicted for BCAM0777 by TMHMM2.0 at aa 3-25, 35-57, 149-171 and 181-203 216591021597 HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 9e-13 216591021598 Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677 216591021599 Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360 216591021600 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591021601 ligand binding site [chemical binding]; other site 216591021602 1 probable transmembrane helix predicted for BCAM0778 by TMHMM2.0 at aa 27-49 216591021603 HMMPfam hit to PF00691, OmpA family, score 9.6e-33 216591021604 Cache domain; Region: Cache_1; pfam02743 216591021605 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591021606 dimerization interface [polypeptide binding]; other site 216591021607 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 216591021608 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591021609 dimer interface [polypeptide binding]; other site 216591021610 putative CheW interface [polypeptide binding]; other site 216591021611 2 probable transmembrane helices predicted for BCAM0779 by TMHMM2.0 at aa 15-37 and 296-318 216591021612 HMMPfam hit to PF00672, HAMP domain, score 2.8e-18 216591021613 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 2.9e-85 216591021614 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 216591021615 ATP binding site [chemical binding]; other site 216591021616 putative Mg++ binding site [ion binding]; other site 216591021617 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591021618 nucleotide binding region [chemical binding]; other site 216591021619 ATP-binding site [chemical binding]; other site 216591021620 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.9e-08 216591021621 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1.6e-12 216591021622 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 2.6e-13 216591021623 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 216591021624 Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228 216591021625 Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299 216591021626 active site 216591021627 HMMPfam hit to PF01979, Amidohydrolase family, score 4.8e-36 216591021628 HMMPfam hit to PF07969, Amidohydrolase family, score 0.00031 216591021629 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591021630 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591021631 putative substrate translocation pore; other site 216591021632 HMMPfam hit to PF00083, Sugar (and other) transporter score 8.5e-23 216591021633 12 probable transmembrane helices predicted for BCAM0783 by TMHMM2.0 at aa 28-50, 65-87, 94-116, 121-140, 160-182, 197-214, 252-274, 284-306, 313-333, 343-365, 378-400 and 410-427 216591021634 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.4e-28 216591021635 PS00216 Sugar transport proteins signature 1. 216591021636 PS00217 Sugar transport proteins signature 2. 216591021637 PS00216 Sugar transport proteins signature 1. 216591021638 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591021639 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591021640 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591021641 dimerization interface [polypeptide binding]; other site 216591021642 substrate binding pocket [chemical binding]; other site 216591021643 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-40 216591021644 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.4e-16 216591021645 PS00044 Bacterial regulatory proteins, lysR family signature. 216591021646 Predicted helix-turn-helix motif with score 1947.000, SD 5.82 at aa 34-55, sequence ASFTKAAAELHLTQSAISRQIQ 216591021647 TIGR02594 family protein; Region: TIGR02594 216591021648 Protein of unknown function (DUF1493); Region: DUF1493; pfam07377 216591021649 HMMPfam hit to PF07377, Protein of unknown function (DUF1493), score 1.9e-07 216591021650 CDS contains a frameshift after codon 88. Similar to Burkholderia xenovorans (strain LB400) putative membrane protein UniProt:Q13UH2 (EMBL:CP000270 (143 aa) fasta scores: E()=8.2e-27, 58.741% id in 143 aa 216591021651 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591021652 HMMPfam hit to PF02321, Outer membrane efflux protein, score 6.4e-23 216591021653 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.9e-20 216591021654 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021655 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591021656 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591021657 putative substrate translocation pore; other site 216591021658 13 probable transmembrane helices predicted for BCAM0791 by TMHMM2.0 at aa 19-41, 56-78, 85-107, 113-135, 142-164, 174-196, 209-226, 241-260, 280-302, 312-334, 341-360, 407-426 and 488-510 216591021659 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.9e-46 216591021660 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021661 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021662 efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998 216591021663 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591021664 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591021665 HMMPfam hit to PF00529, HlyD family secretion protein, score 5e-39 216591021666 1 probable transmembrane helix predicted for BCAM0792 by TMHMM2.0 at aa 28-50 216591021667 Transcriptional regulators [Transcription]; Region: MarR; COG1846 216591021668 MarR family; Region: MarR_2; pfam12802 216591021669 HMMPfam hit to PF01047, MarR family, score 0.0022 216591021670 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591021671 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591021672 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591021673 putative effector binding pocket; other site 216591021674 dimerization interface [polypeptide binding]; other site 216591021675 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.5e-33 216591021676 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 8.6e-19 216591021677 PS00044 Bacterial regulatory proteins, lysR family signature. 216591021678 Predicted helix-turn-helix motif with score 1444.000, SD 4.11 at aa 17-38, sequence RSFTRAADMHGLARPVVSRAVA 216591021679 Transcriptional regulators [Transcription]; Region: MarR; COG1846 216591021680 MarR family; Region: MarR_2; pfam12802 216591021681 HMMPfam hit to PF01047, MarR family, score 4.5e-12 216591021682 Predicted helix-turn-helix motif with score 983.000, SD 2.53 at aa 64-85, sequence LLMSELADMLVMDRTTLLRALK 216591021683 Protein of unknown function (DUF521); Region: DUF521; pfam04412 216591021684 Putative Aconitase X catalytic domain; Region: AcnX; cd01355 216591021685 substrate binding site [chemical binding]; other site 216591021686 ligand binding site [chemical binding]; other site 216591021687 HMMPfam hit to PF04412, Protein of unknown function (DUF521), score 4.9e-156 216591021688 Putative Aconitase X swivel domain. It is predicted by comparative genomic analysis. The proteins are mainly found in archaea and proteobacteria. They are distantly related to Aconitase family of proteins by sequence similarity and seconary structure...; Region: AcnX_swivel; cd01356 216591021689 substrate binding site [chemical binding]; other site 216591021690 HMMPfam hit to PF01989, Protein of unknown function DUF126, score 1.5e-07 216591021691 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 216591021692 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591021693 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591021694 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 5.2e-09 216591021695 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 216591021696 2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930 216591021697 active site 216591021698 FMN binding site [chemical binding]; other site 216591021699 2,4-decadienoyl-CoA binding site; other site 216591021700 catalytic residue [active] 216591021701 4Fe-4S cluster binding site [ion binding]; other site 216591021702 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 216591021703 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 4.5e-111 216591021704 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoredu, score 2.3e-06 216591021705 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021706 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoredu, score 0.00021 216591021707 Protein of unknown function (DUF2471); Region: DUF2471; pfam10616 216591021708 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591021709 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591021710 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_3; cd08461 216591021711 putative substrate binding pocket [chemical binding]; other site 216591021712 putative dimerization interface [polypeptide binding]; other site 216591021713 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.6e-32 216591021714 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.9e-18 216591021715 PS00044 Bacterial regulatory proteins, lysR family signature. 216591021716 Predicted helix-turn-helix motif with score 1802.000, SD 5.32 at aa 30-51, sequence HNVTRAAEKLNMSQPSVSVQLQ 216591021717 Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249 216591021718 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591021719 HMMPfam hit to PF02525, Flavodoxin-like fold, score 3.8e-94 216591021720 muconolactone delta-isomerase; Region: muco_delta; TIGR03221 216591021721 HMMPfam hit to PF02426, Muconolactone delta-isomerase, score 4.2e-60 216591021722 catechol 1,2-dioxygenase, proteobacterial; Region: catechol_proteo; TIGR02439 216591021723 Catechol 1,2 dioxygenase (1,2-CTD) catalyzes an intradiol cleavage reaction of catechol to form cis,cis-muconate. 1,2-CTDs is homodimers with one catalytic non-heme ferric ion per monomer. They belong to the aromatic dioxygenase family, a family of...; Region: 1,2-CTD; cd03460 216591021724 dimer interface [polypeptide binding]; other site 216591021725 active site 216591021726 HMMPfam hit to PF00775, Dioxygenase, score 1.2e-103 216591021727 PS00083 Intradiol ring-cleavage dioxygenases signature. 216591021728 HMMPfam hit to PF04444, Catechol dioxygenase N terminus, score 1.4e-34 216591021729 Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis,cis-muconate (CCM) to muconolactone (ML) in the catechol branch of the beta-ketoadipate pathway. This pathway is used in soil microbes to breakdown lignin-derived...; Region: MLE; cd03318 216591021730 muconate and chloromuconate cycloisomerases; Region: mucon_cyclo; TIGR02534 216591021731 octamer interface [polypeptide binding]; other site 216591021732 active site 216591021733 HMMPfam hit to PF01188, Mandelate racemase / muconate lactonizing en, score 1e-91 216591021734 PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 216591021735 HMMPfam hit to PF02746, Mandelate racemase / muconate lactonizing en, score 1.6e-45 216591021736 PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 216591021737 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591021738 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 216591021739 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591021740 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in benzoate catabolism; contains the type 2 periplasmic binding fold; Region: PBP2_BenM_CatM_CatR; cd08445 216591021741 dimerizarion interface [polypeptide binding]; other site 216591021742 CrgA pocket; other site 216591021743 substrate binding pocket [chemical binding]; other site 216591021744 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.4e-23 216591021745 Predicted helix-turn-helix motif with score 1943.000, SD 5.80 at aa 16-37, sequence MNITRAAERLHMTQPPLSRQLQ 216591021746 PS00044 Bacterial regulatory proteins, lysR family signature. 216591021747 HMMPfam hit to PF03466, LysR substrate binding domain, score 9e-48 216591021748 Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729 216591021749 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144 216591021750 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591021751 dimerization interface [polypeptide binding]; other site 216591021752 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591021753 dimer interface [polypeptide binding]; other site 216591021754 Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015 216591021755 putative CheW interface [polypeptide binding]; other site 216591021756 2 probable transmembrane helices predicted for BCAM0807 by TMHMM2.0 at aa 12-34 and 184-206 216591021757 HMMPfam hit to PF00672, HAMP domain, score 4.5e-10 216591021758 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 2.6e-85 216591021759 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591021760 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591021761 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.2e-08 216591021762 PS00041 Bacterial regulatory proteins, araC family signature. 216591021763 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 7e-05 216591021764 Rieske non-heme iron oxygenase (RO) family, Ortho-halobenzoate-1,2-dioxygenase (OHBDO)-like subfamily, N-terminal Rieske domain of the oxygenase alpha subunit; composed of the oxygenase alpha subunits of OHBDO, salicylate 5-hydroxylase (S5H); Region: Rieske_RO_Alpha_OHBDO_like; cd03545 216591021765 C-terminal catalytic domain of the large/alpha subunit (ahdA1c) of a ring-hydroxylating dioxygenase from Sphingomonas sp. strain P2 and related proteins; Region: RHO_alpha_C_ahdA1c-like; cd08880 216591021766 putative alpha subunit interface [polypeptide binding]; other site 216591021767 putative active site [active] 216591021768 putative substrate binding site [chemical binding]; other site 216591021769 Fe binding site [ion binding]; other site 216591021770 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 4.8e-31 216591021771 PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 216591021772 HMMPfam hit to PF00848, Ring hydroxylating alpha subunit (cat, score 4.6e-05 216591021773 Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667 216591021774 inter-subunit interface; other site 216591021775 HMMPfam hit to PF00866, Ring hydroxylating beta subunit, score 3.3e-07 216591021776 Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528 216591021777 [2Fe-2S] cluster binding site [ion binding]; other site 216591021778 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 5.1e-22 216591021779 phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754 216591021780 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591021781 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591021782 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 1.6e-45 216591021783 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 3.3e-26 216591021784 Protein of unknown function (DUF445); Region: DUF445; pfam04286 216591021785 3 probable transmembrane helices predicted for BCAM0814 by TMHMM2.0 at aa 17-39, 44-64 and 402-424 216591021786 HMMPfam hit to PF04286, Protein of unknown function (DUF445), score 1.1e-109 216591021787 probable addiction module antidote protein; Region: dnstrm_HI1420; TIGR02684 216591021788 Predicted helix-turn-helix motif with score 1328.000, SD 3.71 at aa 50-71, sequence RGMSQVARDAGLSREGLYKALS 216591021789 putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683 216591021790 HMMPfam hit to PF05973, Phage derived protein Gp49-like (DUF891), score 1.1e-11 216591021791 acetolactate synthase; Reviewed; Region: PRK08322 216591021792 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 216591021793 PYR/PP interface [polypeptide binding]; other site 216591021794 dimer interface [polypeptide binding]; other site 216591021795 TPP binding site [chemical binding]; other site 216591021796 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591021797 Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010 216591021798 TPP-binding site [chemical binding]; other site 216591021799 dimer interface [polypeptide binding]; other site 216591021800 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 2.4e-50 216591021801 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 7.2e-21 216591021802 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 2.8e-55 216591021803 PS00187 Thiamine pyrophosphate enzymes signature. 216591021804 Aldehyde dehydrogenase family 21A1-like; Region: ALDH_F21_RNP123; cd07147 216591021805 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591021806 NAD(P) binding site [chemical binding]; other site 216591021807 catalytic residues [active] 216591021808 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.3e-164 216591021809 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591021810 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021811 NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025 216591021812 12 probable transmembrane helices predicted for BCAM0819 by TMHMM2.0 at aa 5-24, 31-53, 57-76, 83-105, 110-132, 153-175, 185-207, 214-236, 266-288, 301-323, 351-373 and 380-402 216591021813 HMMPfam hit to PF00999, Sodium/hydrogen exchanger family, score 1e-58 216591021814 Response regulator receiver domain; Region: Response_reg; pfam00072 216591021815 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591021816 active site 216591021817 phosphorylation site [posttranslational modification] 216591021818 intermolecular recognition site; other site 216591021819 dimerization interface [polypeptide binding]; other site 216591021820 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591021821 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080 216591021822 dimer interface [polypeptide binding]; other site 216591021823 phosphorylation site [posttranslational modification] 216591021824 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591021825 Mg2+ binding site [ion binding]; other site 216591021826 G-X-G motif; other site 216591021827 HMMPfam hit to PF00072, Response regulator receiver domain, score 5.4e-23 216591021828 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.0013 216591021829 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 4.2e-26 216591021830 Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729 216591021831 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 216591021832 HAMP domain; Region: HAMP; pfam00672 216591021833 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591021834 dimer interface [polypeptide binding]; other site 216591021835 putative CheW interface [polypeptide binding]; other site 216591021836 2 probable transmembrane helices predicted for BCAM0821 by TMHMM2.0 at aa 28-47 and 204-226 216591021837 HMMPfam hit to PF00672, HAMP domain, score 9.4e-16 216591021838 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 2.2e-26 216591021839 CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588 216591021840 HMMPfam hit to PF01584, CheW-like domain, score 8.7e-16 216591021841 Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352 216591021842 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591021843 S-adenosylmethionine binding site [chemical binding]; other site 216591021844 HMMPfam hit to PF01739, CheR methyltransferase, SAM binding domain, score 1.6e-46 216591021845 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0018 216591021846 Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835 216591021847 HMMPfam hit to PF01584, CheW-like domain, score 1.1e-19 216591021848 Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088 216591021849 putative binding surface; other site 216591021850 active site 216591021851 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591021852 ATP binding site [chemical binding]; other site 216591021853 Mg2+ binding site [ion binding]; other site 216591021854 G-X-G motif; other site 216591021855 CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256 216591021856 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591021857 Response regulator receiver domain; Region: Response_reg; pfam00072 216591021858 active site 216591021859 phosphorylation site [posttranslational modification] 216591021860 intermolecular recognition site; other site 216591021861 dimerization interface [polypeptide binding]; other site 216591021862 HMMPfam hit to PF01627, Hpt domain, score 2.1e-10 216591021863 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 1.1e-22 216591021864 HMMPfam hit to PF01584, CheW-like domain, score 2.6e-15 216591021865 HMMPfam hit to PF00072, Response regulator receiver domain, score 6.5e-31 216591021866 chemotaxis-specific methylesterase; Provisional; Region: PRK12555 216591021867 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591021868 active site 216591021869 phosphorylation site [posttranslational modification] 216591021870 intermolecular recognition site; other site 216591021871 dimerization interface [polypeptide binding]; other site 216591021872 CheB methylesterase; Region: CheB_methylest; pfam01339 216591021873 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.6e-14 216591021874 HMMPfam hit to PF01339, CheB methylesterase, score 2.8e-60 216591021875 ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation...; Region: ClC_sycA_like; cd03682 216591021876 Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038 216591021877 putative Cl- selectivity filter; other site 216591021878 putative pore gating glutamate residue; other site 216591021879 8 probable transmembrane helices predicted for BCAM0827 by TMHMM2.0 at aa 74-96, 106-128, 201-223, 273-295, 307-329, 360-382, 389-411 and 426-448 216591021880 HMMPfam hit to PF00654, Voltage gated chloride channel, score 5.6e-22 216591021881 riboflavin synthase subunit alpha; Provisional; Region: PRK13020 216591021882 Lumazine binding domain; Region: Lum_binding; pfam00677 216591021883 Lumazine binding domain; Region: Lum_binding; pfam00677 216591021884 HMMPfam hit to PF00677, Lumazine binding domain, score 1.3e-23 216591021885 HMMPfam hit to PF00677, Lumazine binding domain, score 1.5e-22 216591021886 PS00693 Riboflavin synthase alpha chain family signature. 216591021887 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 216591021888 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591021889 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 0.00032 216591021890 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 216591021891 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265 216591021892 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591021893 Walker A/P-loop; other site 216591021894 ATP binding site [chemical binding]; other site 216591021895 Q-loop/lid; other site 216591021896 ABC transporter signature motif; other site 216591021897 Walker B; other site 216591021898 D-loop; other site 216591021899 H-loop/switch region; other site 216591021900 HMMPfam hit to PF00005, ABC transporter score 1.2e-65 216591021901 PS00211 ABC transporters family signature. 216591021902 PS00017 ATP/GTP-binding site motif A (P-loop). 216591021903 6 probable transmembrane helices predicted for BCAM0831 by TMHMM2.0 at aa 31-53, 68-90, 151-173, 178-200, 259-281 and 291-308 216591021904 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1.2e-06 216591021905 Dyp-type peroxidase family; Region: Dyp_perox_fam; TIGR01413 216591021906 HMMPfam hit to PF04261, Dyp-type peroxidase family, score 1.3e-83 216591021907 Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765 216591021908 HMMPfam hit to PF02566, OsmC-like protein, score 1.1e-28 216591021909 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591021910 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591021911 The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417 216591021912 substrate binding pocket [chemical binding]; other site 216591021913 dimerization interface [polypeptide binding]; other site 216591021914 HMMPfam hit to PF03466, LysR substrate binding domain, score 6e-20 216591021915 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.3e-22 216591021916 PS00044 Bacterial regulatory proteins, lysR family signature. 216591021917 Predicted helix-turn-helix motif with score 1603.000, SD 4.65 at aa 22-43, sequence GGIGAAARALHLTQPAVTHALN 216591021918 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591021919 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.8e-05 216591021920 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00016 216591021921 manganese transport protein MntH; Reviewed; Region: PRK00701 216591021922 Natural resistance-associated macrophage protein; Region: Nramp; pfam01566 216591021923 HMMPfam hit to PF01566, Natural resistance-associated macrophage pro, score 1.6e-139 216591021924 9 probable transmembrane helices predicted for BCAM0836 by TMHMM2.0 at aa 63-85, 138-160, 167-189, 213-232, 261-283, 298-320, 351-368, 373-395 and 415-437 216591021925 6 probable transmembrane helices predicted for BCAM0837 by TMHMM2.0 at aa 5-27, 32-54, 69-91, 98-115, 125-142 and 149-171 216591021926 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591021927 short chain dehydrogenase; Validated; Region: PRK07069 216591021928 NAD(P) binding site [chemical binding]; other site 216591021929 active site 216591021930 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.9e-25 216591021931 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00088 216591021932 PS00061 Short-chain dehydrogenases/reductases family signature. 216591021933 Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130 216591021934 Prostaglandin dehydrogenases; Region: PGDH; cd05288 216591021935 NAD(P) binding site [chemical binding]; other site 216591021936 substrate binding site [chemical binding]; other site 216591021937 dimer interface [polypeptide binding]; other site 216591021938 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 0.003 216591021939 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021940 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.6e-25 216591021941 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628 216591021942 Domain of unknown function DUF20; Region: UPF0118; pfam01594 216591021943 HMMPfam hit to PF01594, Domain of unknown function DUF20, score 2.6e-51 216591021944 7 probable transmembrane helices predicted for BCAM0842 by TMHMM2.0 at aa 10-43, 63-85, 154-176, 216-238, 248-270, 277-299 and 314-336 216591021945 The SYLF domain (also called DUF500), a novel lipid-binding module; Region: SYLF; cd11524 216591021946 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021947 Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957 216591021948 HMMPfam hit to PF05957, Bacterial protein of unknown function (DUF88, score 5.2e-14 216591021949 YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486 216591021950 generic binding surface I; other site 216591021951 generic binding surface II; other site 216591021952 Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283 216591021953 putative active site [active] 216591021954 putative catalytic site [active] 216591021955 putative Mg binding site IVb [ion binding]; other site 216591021956 putative phosphate binding site [ion binding]; other site 216591021957 putative DNA binding site [nucleotide binding]; other site 216591021958 putative Mg binding site IVa [ion binding]; other site 216591021959 HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 8.9e-22 216591021960 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021961 YCII-related domain; Region: YCII; cl00999 216591021962 HMMPfam hit to PF04946, DGPF domain, score 1.2e-30 216591021963 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3795 216591021964 HMMPfam hit to PF04946, DGPF domain, score 6.1e-41 216591021965 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591021966 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_24; cd09012 216591021967 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 7.3e-07 216591021968 Predicted RNA polymerase sigma factor containing a TPR repeat domain [Transcription]; Region: COG4941 216591021969 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591021970 HMMPfam hit to PF04542, Sigma-70 region, score 2.2e-11 216591021971 HMMPfam hit to PF08281, Sigma-70, region, score 4e-09 216591021972 Predicted helix-turn-helix motif with score 1031.000, SD 2.70 at aa 147-168, sequence LTTGEIARAFLTPEPTIAQRIV 216591021973 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021974 Rubrerythrin [Energy production and conversion]; Region: COG1592 216591021975 Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041 216591021976 binuclear metal center [ion binding]; other site 216591021977 HMMPfam hit to PF02915, Rubrerythrin, score 7.6e-33 216591021978 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 216591021979 Cysteine-rich domain; Region: CCG; pfam02754 216591021980 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591021981 Protein of unknown function (DUF3501); Region: DUF3501; pfam12007 216591021982 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 216591021983 GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509 216591021984 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479 216591021985 Substrate binding site; other site 216591021986 Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050 216591021987 HMMPfam hit to PF01050, Mannose-6-phosphate isomerase, score 3.3e-120 216591021988 HMMPfam hit to PF07883, Cupin domain, score 7.2e-12 216591021989 HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.2e-90 216591021990 CDS contains a frameshift and 11 bp deletion after codon 139. Similar to Escherichia coli putative colanic biosynthesis UDP-glucose lipid carrier transferase WcaJ UniProt:P71241 (EMBL:AP009048 (464 aa) fasta scores: E()=4.1e-58, 40.260% id in 462 aa 216591021991 HMMPfam hit to PF02397, Bacterial sugar transferase, score 2.1e-38 216591021992 Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004 216591021993 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210 216591021994 UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984 216591021995 UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984 216591021996 HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 2.1e-90 216591021997 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591021998 HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 2.2e-47 216591021999 HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 1.1e-35 216591022000 Low molecular weight phosphatase family; Region: LMWPc; cd00115 216591022001 Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451 216591022002 active site 216591022003 HMMPfam hit to PF01451, Low molecular weight phosphotyrosine protein, score 2.1e-30 216591022004 polysaccharide export protein Wza; Provisional; Region: PRK15078 216591022005 Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563 216591022006 SLBB domain; Region: SLBB; pfam10531 216591022007 SLBB domain; Region: SLBB; pfam10531 216591022008 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022009 HMMPfam hit to PF02563, Polysaccharide biosynthesis/export protei, score 2.8e-28 216591022010 tyrosine kinase; Provisional; Region: PRK11519 216591022011 Chain length determinant protein; Region: Wzz; pfam02706 216591022012 G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807 216591022013 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 216591022014 P-loop; other site 216591022015 Magnesium ion binding site [ion binding]; other site 216591022016 HMMPfam hit to PF02706, Chain length determinant protein, score 3.5e-34 216591022017 2 probable transmembrane helices predicted for BCAM0859 by TMHMM2.0 at aa 34-56 and 450-469 216591022018 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 216591022019 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 216591022020 active site 216591022021 HMMPfam hit to PF00535, Glycosyl transferase family, score 1.5e-22 216591022022 PS00215 Mitochondrial energy transfer proteins signature. 216591022023 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 216591022024 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591022025 10 probable transmembrane helices predicted for BCAM0862 by TMHMM2.0 at aa 44-62, 93-115, 127-149, 182-204, 238-255, 265-287, 300-322, 394-416, 429-446 and 450-472 216591022026 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 216591022027 Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439 216591022028 HMMPfam hit to PF00534, Glycosyl transferases group, score 3.1e-31 216591022029 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591022030 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 216591022031 HMMPfam hit to PF00534, Glycosyl transferases group, score 1.3e-37 216591022032 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591022033 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591022034 12 probable transmembrane helices predicted for BCAM0865 by TMHMM2.0 at aa 27-49, 64-86, 98-120, 124-146, 153-175, 180-202, 233-255, 270-292, 299-316, 320-342, 358-380 and 384-406 216591022035 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.1e-34 216591022036 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022037 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022038 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022039 Predicted transcriptional regulators [Transcription]; Region: COG1733 216591022040 HxlR-like helix-turn-helix; Region: HxlR; pfam01638 216591022041 HMMPfam hit to PF01638, HxlR-like helix-turn-helix, score 3.8e-18 216591022042 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591022043 putative substrate translocation pore; other site 216591022044 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591022045 12 probable transmembrane helices predicted for BCAM0867 by TMHMM2.0 at aa 21-43, 53-75, 88-110, 144-166, 173-195, 234-256, 277-299, 309-331, 344-361, 371-393, 414-436 and 441-458 216591022046 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 9.5e-62 216591022047 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591022048 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022049 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591022050 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591022051 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591022052 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 4.9e-06 216591022053 PS00041 Bacterial regulatory proteins, araC family signature. 216591022054 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.6e-06 216591022055 FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545 216591022056 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 216591022057 HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomeras, score 1.8e-55 216591022058 PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2. 216591022059 PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1. 216591022060 PS00017 ATP/GTP-binding site motif A (P-loop). 216591022061 Predicted metal-dependent hydrolase [General function prediction only]; Region: COG3687 216591022062 Predicted metal-dependent hydrolase; Region: Metal_hydrol; pfam10118 216591022063 1 probable transmembrane helix predicted for BCAM0870 by TMHMM2.0 at aa 196-218 216591022064 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 216591022065 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591022066 Walker A motif; other site 216591022067 ATP binding site [chemical binding]; other site 216591022068 Walker B motif; other site 216591022069 arginine finger; other site 216591022070 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591022071 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3e-138 216591022072 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591022073 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591022074 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 2.3e-08 216591022075 Predicted helix-turn-helix motif with score 1460.000, SD 4.16 at aa 421-442, sequence HRINKAAAELGISRVTLYRMMI 216591022076 Predicted membrane protein [Function unknown]; Region: COG2246 216591022077 GtrA-like protein; Region: GtrA; pfam04138 216591022078 HMMPfam hit to PF04138, GtrA-like protein, score 1.5e-10 216591022079 4 probable transmembrane helices predicted for BCAM0872 by TMHMM2.0 at aa 12-34, 44-66, 73-92 and 102-124 216591022080 lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096 216591022081 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591022082 substrate binding pocket [chemical binding]; other site 216591022083 membrane-bound complex binding site; other site 216591022084 hinge residues; other site 216591022085 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 3.1e-87 216591022086 PS00017 ATP/GTP-binding site motif A (P-loop). 216591022087 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591022088 Protein of unknown function (DUF2384); Region: DUF2384; pfam09722 216591022089 RES domain; Region: RES; smart00953 216591022090 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 216591022091 active site 216591022092 metal binding site [ion binding]; metal-binding site 216591022093 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 5.8e-11 216591022094 PS00125 Serine/threonine specific protein phosphatases signature. 216591022095 Protein of unknown function (DUF1345); Region: DUF1345; pfam07077 216591022096 HMMPfam hit to PF07077, Protein of unknown function (DUF1345), score 1.5e-80 216591022097 5 probable transmembrane helices predicted for BCAM0878 by TMHMM2.0 at aa 13-32, 36-58, 79-101, 111-133 and 194-216 216591022098 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591022099 GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046 216591022100 putative C-terminal domain interface [polypeptide binding]; other site 216591022101 putative GSH binding site (G-site) [chemical binding]; other site 216591022102 putative dimer interface [polypeptide binding]; other site 216591022103 C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189 216591022104 putative N-terminal domain interface [polypeptide binding]; other site 216591022105 putative dimer interface [polypeptide binding]; other site 216591022106 putative substrate binding pocket (H-site) [chemical binding]; other site 216591022107 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 5.4e-12 216591022108 PS00017 ATP/GTP-binding site motif A (P-loop). 216591022109 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591022110 S-adenosylmethionine binding site [chemical binding]; other site 216591022111 HMMPfam hit to PF08241, Methyltransferase domain, score 5.8e-14 216591022112 HMMPfam hit to PF08242, Methyltransferase domain, score 3.8e-14 216591022113 N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853 216591022114 Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893 216591022115 active site 216591022116 catalytic site [active] 216591022117 Domain of unknown function (DUF3459); Region: DUF3459; pfam11941 216591022118 HMMPfam hit to PF02922, Isoamylase N-terminal domain, score 1.1e-07 216591022119 Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564 216591022120 active site 216591022121 thiamine phosphate binding site [chemical binding]; other site 216591022122 pyrophosphate binding site [ion binding]; other site 216591022123 HMMPfam hit to PF02581, Thiamine monophosphate synthase/TENI, score 3.3e-36 216591022124 Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253 216591022125 Domain of unknown function DUF21; Region: DUF21; pfam01595 216591022126 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 216591022127 Transporter associated domain; Region: CorC_HlyC; smart01091 216591022128 HMMPfam hit to PF03471, Transporter associated domain, score 2.8e-13 216591022129 HMMPfam hit to PF00571, CBS domain pair, score 1.8e-21 216591022130 HMMPfam hit to PF01595, Domain of unknown function DUF21, score 3.1e-68 216591022131 4 probable transmembrane helices predicted for BCAM0883 by TMHMM2.0 at aa 5-27, 65-87, 102-124 and 136-158 216591022132 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591022133 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591022134 dimer interface [polypeptide binding]; other site 216591022135 phosphorylation site [posttranslational modification] 216591022136 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518 216591022137 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.9e-09 216591022138 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 216591022139 10 probable transmembrane helices predicted for BCAM0885 by TMHMM2.0 at aa 12-31, 41-63, 76-98, 102-124, 131-148, 159-178, 185-207, 217-239, 246-268 and 273-295 216591022140 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.8e-17 216591022141 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022142 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.5e-14 216591022143 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591022144 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591022145 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591022146 dimerization interface [polypeptide binding]; other site 216591022147 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-22 216591022148 PS00044 Bacterial regulatory proteins, lysR family signature. 216591022149 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.4e-17 216591022150 PS00044 Bacterial regulatory proteins, lysR family signature. 216591022151 Predicted helix-turn-helix motif with score 1595.000, SD 4.62 at aa 19-40, sequence ASFTRAADALGTTQSAVSLKLK 216591022152 4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235 216591022153 active site 1 [active] 216591022154 dimer interface [polypeptide binding]; other site 216591022155 hexamer interface [polypeptide binding]; other site 216591022156 active site 2 [active] 216591022157 4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235 216591022158 HMMPfam hit to PF01361, Tautomerase enzyme, score 8.4e-11 216591022159 HMMPfam hit to PF01361, Tautomerase enzyme, score 6.4e-05 216591022160 CHAD domain; Region: CHAD; pfam05235 216591022161 HMMPfam hit to PF05235, CHAD domain, score 1.5e-21 216591022162 N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005 216591022163 DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676 216591022164 Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585 216591022165 molybdenum-pterin binding domain; Region: Mop; TIGR00638 216591022166 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 1.2e-17 216591022167 HMMPfam hit to PF03459, TOBE domain, score 6.4e-18 216591022168 HMMPfam hit to PF03459, TOBE domain, score 4.1e-17 216591022169 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591022170 sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968 216591022171 Walker A/P-loop; other site 216591022172 ATP binding site [chemical binding]; other site 216591022173 Q-loop/lid; other site 216591022174 ABC transporter signature motif; other site 216591022175 Walker B; other site 216591022176 D-loop; other site 216591022177 H-loop/switch region; other site 216591022178 HMMPfam hit to PF00005, ABC transporter score 7.8e-57 216591022179 PS00211 ABC transporters family signature. 216591022180 PS00017 ATP/GTP-binding site motif A (P-loop). 216591022181 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591022182 dimer interface [polypeptide binding]; other site 216591022183 conserved gate region; other site 216591022184 putative PBP binding loops; other site 216591022185 ABC-ATPase subunit interface; other site 216591022186 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.5e-20 216591022187 5 probable transmembrane helices predicted for BCAM0891 by TMHMM2.0 at aa 15-34, 47-69, 84-104, 145-167 and 195-217 216591022188 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591022189 Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531 216591022190 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 216591022191 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 2.9e-10 216591022192 1 probable transmembrane helix predicted for BCAM0892 by TMHMM2.0 at aa 12-34 216591022193 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 216591022194 active site 216591022195 6 probable transmembrane helices predicted for BCAM0893 by TMHMM2.0 at aa 10-32, 45-67, 77-96, 103-125, 130-152 and 159-181 216591022196 HMMPfam hit to PF01569, PAP2 superfamily, score 0.00029 216591022197 Esterase PHB depolymerase; Region: Esterase_phd; pfam10503 216591022198 Protein of unknown function (DUF3563); Region: DUF3563; pfam12086 216591022199 peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561 216591022200 HMMPfam hit to PF02566, OsmC-like protein, score 4.9e-37 216591022201 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591022202 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591022203 putative Zn2+ binding site [ion binding]; other site 216591022204 putative DNA binding site [nucleotide binding]; other site 216591022205 HMMPfam hit to PF01047, MarR family, score 3.8e-22 216591022206 6 probable transmembrane helices predicted for BCAM0898 by TMHMM2.0 at aa 21-43, 47-69, 97-119, 152-174, 195-217 and 227-249 216591022207 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022208 Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334 216591022209 Homoserine Kinase, type II. Homoserine kinase is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and...; Region: HomoserineK_II; cd05153 216591022210 putative active site [active] 216591022211 putative substrate binding site [chemical binding]; other site 216591022212 ATP binding site [chemical binding]; other site 216591022213 HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 3.2e-33 216591022214 1 probable transmembrane helix predicted for BCAM0900 by TMHMM2.0 at aa 4-23 216591022215 AMP nucleosidase; Provisional; Region: PRK08292 216591022216 Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423 216591022217 Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775 216591022218 HMMPfam hit to PF01048, Phosphorylase family, score 1.9e-35 216591022219 2 probable transmembrane helices predicted for BCAM0902 by TMHMM2.0 at aa 5-24 and 34-56 216591022220 Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611 216591022221 HMMPfam hit to PF03641, Possible lysine decarboxylase, score 7.6e-53 216591022222 DNA polymerase I; Provisional; Region: PRK05755 216591022223 PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859 216591022224 active site 216591022225 metal binding site 1 [ion binding]; metal-binding site 216591022226 putative 5' ssDNA interaction site; other site 216591022227 metal binding site 3; metal-binding site 216591022228 metal binding site 2 [ion binding]; metal-binding site 216591022229 H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898 216591022230 putative DNA binding site [nucleotide binding]; other site 216591022231 putative metal binding site [ion binding]; other site 216591022232 DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139 216591022233 active site 216591022234 catalytic site [active] 216591022235 substrate binding site [chemical binding]; other site 216591022236 Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637 216591022237 active site 216591022238 DNA binding site [nucleotide binding] 216591022239 catalytic site [active] 216591022240 HMMPfam hit to PF02739, 5'-3' exonuclease, N-terminal resolvase-, score 4.7e-77 216591022241 HMMPfam hit to PF01367, 5'-3' exonuclease, C-terminal SAM fold, score 5.6e-28 216591022242 HMMPfam hit to PF01612, 3'-5' exonuclease, score 1e-40 216591022243 HMMPfam hit to PF00476, DNA polymerase family A, score 2.9e-193 216591022244 PS00447 DNA polymerase family A signature. 216591022245 NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252 216591022246 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591022247 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 2.4e-19 216591022248 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 6e-12 216591022249 1 probable transmembrane helix predicted for BCAM0905 by TMHMM2.0 at aa 381-403 216591022250 Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412 216591022251 BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840 216591022252 HMMPfam hit to PF01738, Dienelactone hydrolase family, score 3.8e-73 216591022253 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125 216591022254 Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897 216591022255 active site residue [active] 216591022256 Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449 216591022257 active site residue [active] 216591022258 HMMPfam hit to PF00581, Rhodanese-like domain, score 2.5e-13 216591022259 PS00340 Growth factor and cytokines receptors family signature 2. 216591022260 PS00683 Rhodanese C-terminal signature. 216591022261 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022262 HMMPfam hit to PF00581, Rhodanese-like domain, score 1.3e-08 216591022263 PS00380 Rhodanese signature 1. 216591022264 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 216591022265 Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469 216591022266 [2Fe-2S] cluster binding site [ion binding]; other site 216591022267 C-terminal catalytic domain of the oxygenase alpha subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C; cd00680 216591022268 alpha subunit interface [polypeptide binding]; other site 216591022269 active site 216591022270 substrate binding site [chemical binding]; other site 216591022271 Fe binding site [ion binding]; other site 216591022272 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022273 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 4.7e-17 216591022274 exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977 216591022275 HMMPfam hit to PF02609, Exonuclease VII small subunit, score 1.2e-17 216591022276 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142 216591022277 Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685 216591022278 substrate binding pocket [chemical binding]; other site 216591022279 chain length determination region; other site 216591022280 substrate-Mg2+ binding site; other site 216591022281 catalytic residues [active] 216591022282 aspartate-rich region 1; other site 216591022283 active site lid residues [active] 216591022284 aspartate-rich region 2; other site 216591022285 HMMPfam hit to PF00348, Polyprenyl synthetase, score 4.2e-89 216591022286 PS00723 Polyprenyl synthetases signature 1. 216591022287 PS00444 Polyprenyl synthetases signature 2. 216591022288 1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444 216591022289 Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007 216591022290 TPP-binding site; other site 216591022291 Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033 216591022292 PYR/PP interface [polypeptide binding]; other site 216591022293 dimer interface [polypeptide binding]; other site 216591022294 TPP binding site [chemical binding]; other site 216591022295 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 216591022296 PS00801 Transketolase signature 1. 216591022297 HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 2.3e-66 216591022298 PS00802 Transketolase signature 2. 216591022299 HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 6.9e-34 216591022300 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022301 putative GTP cyclohydrolase; Provisional; Region: PRK13674 216591022302 HMMPfam hit to PF02649, Uncharacterized ACR, COG1469, score 6e-37 216591022303 UGMP family protein; Validated; Region: PRK09604 216591022304 tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725 216591022305 HMMPfam hit to PF00814, Glycoprotease family, score 2.2e-77 216591022306 Predicted flavoproteins [General function prediction only]; Region: COG2081 216591022307 HMMPfam hit to PF03486, HI0933-like protein, score 2.6e-194 216591022308 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00024 216591022309 HMMPfam hit to PF00890, FAD binding domain, score 0.0052 216591022310 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 0.0019 216591022311 30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270 216591022312 HMMPfam hit to PF01165, Ribosomal protein S21, score 3.8e-32 216591022313 Yqey-like protein; Region: YqeY; pfam09424 216591022314 HMMPfam hit to PF02637, GatB/Yqey domain, score 9.6e-45 216591022315 DNA primase; Validated; Region: dnaG; PRK05667 216591022316 CHC2 zinc finger; Region: zf-CHC2; pfam01807 216591022317 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 216591022318 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 216591022319 active site 216591022320 metal binding site [ion binding]; metal-binding site 216591022321 interdomain interaction site; other site 216591022322 DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410 216591022323 DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; smart00766 216591022324 HMMPfam hit to PF01807, CHC2 zinc finger, score 6.5e-60 216591022325 HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal, score 4e-60 216591022326 HMMPfam hit to PF01751, Toprim domain, score 2.4e-18 216591022327 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022328 HMMPfam hit to PF08278, DNA primase DnaG DnaB-binding, score 0.0014 216591022329 RNA polymerase sigma factor RpoD; Validated; Region: PRK05658 216591022330 Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979 216591022331 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 216591022332 Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546 216591022333 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591022334 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 216591022335 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591022336 DNA binding residues [nucleotide binding] 216591022337 HMMPfam hit to PF03979, Sigma-70 factor, region, score 8.5e-36 216591022338 HMMPfam hit to PF00140, Sigma-70 factor, region, score 1.1e-16 216591022339 HMMPfam hit to PF04546, Sigma-70, non-essential region, score 8.1e-93 216591022340 PS00116 DNA polymerase family B signature. 216591022341 HMMPfam hit to PF04542, Sigma-70 region, score 2.1e-27 216591022342 PS00715 Sigma-70 factors family signature 1. 216591022343 HMMPfam hit to PF04539, Sigma-70 region, score 2.6e-36 216591022344 HMMPfam hit to PF04545, Sigma-70, region, score 1.2e-22 216591022345 Predicted helix-turn-helix motif with score 1917.000, SD 5.72 at aa 578-599, sequence HTLEEVGKQFDVTRERIRQIEA 216591022346 PS00716 Sigma-70 factors family signature 2. 216591022347 Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111 216591022348 putative active site [active] 216591022349 catalytic site [active] 216591022350 Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113 216591022351 PLD-like domain; Region: PLDc_2; pfam13091 216591022352 putative active site [active] 216591022353 catalytic site [active] 216591022354 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022355 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 0.0011 216591022356 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 7.4e-05 216591022357 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591022358 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591022359 DNA-binding site [nucleotide binding]; DNA binding site 216591022360 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591022361 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591022362 homodimer interface [polypeptide binding]; other site 216591022363 catalytic residue [active] 216591022364 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.7e-08 216591022365 PS00136 Serine proteases, subtilase family, aspartic acid active site. 216591022366 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 0.00043 216591022367 Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; pfam12900 216591022368 Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377 216591022369 peptidase domain interface [polypeptide binding]; other site 216591022370 Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056 216591022371 active site 216591022372 catalytic triad [active] 216591022373 calcium binding site [ion binding]; other site 216591022374 HMMPfam hit to PF00082, Subtilase family, score 7.9e-07 216591022375 PS00138 Serine proteases, subtilase family, serine active site. 216591022376 1 probable transmembrane helix predicted for BCAM0922 by TMHMM2.0 at aa 12-34 216591022377 2 probable transmembrane helices predicted for BCAM0923 by TMHMM2.0 at aa 21-43 and 58-80 216591022378 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022379 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591022380 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591022381 active site 216591022382 phosphorylation site [posttranslational modification] 216591022383 intermolecular recognition site; other site 216591022384 dimerization interface [polypeptide binding]; other site 216591022385 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591022386 DNA binding site [nucleotide binding] 216591022387 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 4.8e-16 216591022388 HMMPfam hit to PF00072, Response regulator receiver domain, score 4.5e-34 216591022389 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591022390 HMMPfam hit to PF02321, Outer membrane efflux protein, score 4.2e-51 216591022391 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.2e-42 216591022392 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022393 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915 216591022394 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 216591022395 12 probable transmembrane helices predicted for BCAM0926 by TMHMM2.0 at aa 9-31, 340-359, 366-388, 392-414, 438-460, 470-492, 532-554, 863-885, 892-914, 919-941, 962-984 and 999-1021 216591022396 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 216591022397 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591022398 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591022399 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.3e-42 216591022400 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022401 Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin...; Region: APH; cd05150 216591022402 Phosphotransferase enzyme family; Region: APH; pfam01636 216591022403 active site 216591022404 ATP binding site [chemical binding]; other site 216591022405 antibiotic binding site [chemical binding]; other site 216591022406 HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 1.2e-44 216591022407 VirK protein; Region: VirK; pfam06903 216591022408 Ankyrin repeats (many copies); Region: Ank_4; pfam13637 216591022409 ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204 216591022410 Ankyrin repeats (3 copies); Region: Ank_2; pfam12796 216591022411 HMMPfam hit to PF00023, Ankyrin repeat, score 0.0019 216591022412 HMMPfam hit to PF00023, Ankyrin repeat, score 0.044 216591022413 HMMPfam hit to PF00023, Ankyrin repeat, score 0.013 216591022414 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022415 Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753 216591022416 Clade 1 of the heme-binding enzyme catalase; Region: catalase_clade_1; cd08154 216591022417 tetramer interface [polypeptide binding]; other site 216591022418 heme binding pocket [chemical binding]; other site 216591022419 HMMPfam hit to PF00199, Catalase, score 4e-216 216591022420 PS00437 Catalase proximal heme-ligand signature. 216591022421 PS00438 Catalase proximal active site signature. 216591022422 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591022423 HMMPfam hit to PF02321, Outer membrane efflux protein, score 8.6e-33 216591022424 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.1e-23 216591022425 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022426 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591022427 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591022428 putative substrate translocation pore; other site 216591022429 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591022430 12 probable transmembrane helices predicted for BCAM0933 by TMHMM2.0 at aa 25-47, 60-82, 97-119, 140-162, 177-199, 206-228, 238-260, 280-301, 316-338, 345-367, 413-430 and 498-515 216591022431 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022432 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.3e-53 216591022433 efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998 216591022434 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591022435 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591022436 HMMPfam hit to PF00529, HlyD family secretion protein, score 3.5e-45 216591022437 1 probable transmembrane helix predicted for BCAM0934 by TMHMM2.0 at aa 31-53 216591022438 putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552 216591022439 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591022440 Domain of unknown function (DUF1956); Region: DUF1956; pfam09209 216591022441 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 5.7e-18 216591022442 Predicted helix-turn-helix motif with score 1323.000, SD 3.69 at aa 41-62, sequence ASTREIAAMAGVNAPALQYYFE 216591022443 putative mechanosensitive channel protein; Provisional; Region: PRK11465 216591022444 Mechanosensitive ion channel; Region: MS_channel; pfam00924 216591022445 HMMPfam hit to PF00924, Mechanosensitive ion channel, score 4.2e-46 216591022446 12 probable transmembrane helices predicted for BCAM0936 by TMHMM2.0 at aa 5-27, 148-170, 248-270, 280-302, 326-348, 352-374, 395-417, 437-459, 483-505, 520-542, 563-585 and 590-609 216591022447 PS00287 Cysteine proteases inhibitors signature. 216591022448 luciferase-type oxidoreductase, BA3436 family; Region: lucif_BA3436; TIGR03571 216591022449 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892 216591022450 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892 216591022451 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 2.3e-06 216591022452 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 216591022453 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 0.0019 216591022454 NAD-dependent deacetylase; Provisional; Region: PRK05333 216591022455 SIRT4: Eukaryotic and prokaryotic group (class2) which includes human sirtuin SIRT4 and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein...; Region: SIRT4; cd01409 216591022456 NAD+ binding site [chemical binding]; other site 216591022457 substrate binding site [chemical binding]; other site 216591022458 Zn binding site [ion binding]; other site 216591022459 HMMPfam hit to PF02146, Sir2 family, score 4e-45 216591022460 Methyltransferase domain; Region: Methyltransf_23; pfam13489 216591022461 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591022462 S-adenosylmethionine binding site [chemical binding]; other site 216591022463 HMMPfam hit to PF06080, Protein of unknown function (DUF938), score 2.3e-108 216591022464 HMMPfam hit to PF08241, Methyltransferase domain, score 3.2e-10 216591022465 HMMPfam hit to PF08242, Methyltransferase domain, score 5.2e-05 216591022466 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 216591022467 6-phosphogluconate dehydrogenase; Validated; Region: PRK09287 216591022468 6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393 216591022469 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 7.5e-88 216591022470 HMMPfam hit to PF00393, 6-phosphogluconate dehydrogenase, C-ter, score 2.5e-226 216591022471 PS00461 6-phosphogluconate dehydrogenase signature. 216591022472 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591022473 1 probable transmembrane helix predicted for BCAM0942 by TMHMM2.0 at aa 10-32 216591022474 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 216591022475 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 216591022476 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 216591022477 E3 interaction surface; other site 216591022478 lipoyl attachment site [posttranslational modification]; other site 216591022479 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022480 HMMPfam hit to PF01476, LysM domain, score 2.8e-12 216591022481 HMMPfam hit to PF01551, Peptidase family M23, score 4.4e-29 216591022482 6 probable transmembrane helices predicted for BCAM0945 by TMHMM2.0 at aa 5-27, 42-64, 77-94, 109-126, 138-157 and 172-194 216591022483 Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038 216591022484 HMMPfam hit to PF01292, Cytochrome b561 family, score 7.5e-41 216591022485 4 probable transmembrane helices predicted for BCAM0946 by TMHMM2.0 at aa 13-35, 45-67, 90-112 and 145-167 216591022486 2 probable transmembrane helices predicted for BCAM0946a by TMHMM2.0 at aa 7-29 and 78-100 216591022487 TonB-dependent copper receptor; Region: TonB-copper; TIGR01778 216591022488 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591022489 N-terminal plug; other site 216591022490 ligand-binding site [chemical binding]; other site 216591022491 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.6e-21 216591022492 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022493 HMMPfam hit to PF00593, TonB dependent receptor, score 2.2e-23 216591022494 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075 216591022495 Lipase (class 2); Region: Lipase_2; pfam01674 216591022496 PGAP1-like protein; Region: PGAP1; pfam07819 216591022497 1 probable transmembrane helix predicted for BCAM0949 by TMHMM2.0 at aa 12-34 216591022498 HMMPfam hit to PF07819, PGAP1-like protein, score 0.0013 216591022499 HMMPfam hit to PF05057, Putative serine esterase (DUF676), score 0.00039 216591022500 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 7.1e-27 216591022501 PS00120 Lipases, serine active site. 216591022502 lipase chaperone; Provisional; Region: PRK01294 216591022503 Proteobacterial lipase chaperone protein; Region: Lipase_chap; cl02224 216591022504 1 probable transmembrane helix predicted for BCAM0950 by TMHMM2.0 at aa 13-35 216591022505 HMMPfam hit to PF03280, Proteobacterial lipase chaperone protein, score 2.3e-132 216591022506 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591022507 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591022508 DNA-binding site [nucleotide binding]; DNA binding site 216591022509 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591022510 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591022511 homodimer interface [polypeptide binding]; other site 216591022512 catalytic residue [active] 216591022513 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.2e-08 216591022514 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 1.7e-12 216591022515 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 216591022516 ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300 216591022517 Walker A/P-loop; other site 216591022518 ATP binding site [chemical binding]; other site 216591022519 Q-loop/lid; other site 216591022520 ABC transporter signature motif; other site 216591022521 Walker B; other site 216591022522 D-loop; other site 216591022523 H-loop/switch region; other site 216591022524 TOBE domain; Region: TOBE_2; pfam08402 216591022525 HMMPfam hit to PF00005, ABC transporter score 3.8e-58 216591022526 PS00017 ATP/GTP-binding site motif A (P-loop). 216591022527 PS00211 ABC transporters family signature. 216591022528 HMMPfam hit to PF08402, TOBE domain, score 2.5e-20 216591022529 Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687 216591022530 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 216591022531 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 3.8e-06 216591022532 1 probable transmembrane helix predicted for BCAM0953 by TMHMM2.0 at aa 13-35 216591022533 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591022534 dimer interface [polypeptide binding]; other site 216591022535 conserved gate region; other site 216591022536 putative PBP binding loops; other site 216591022537 ABC-ATPase subunit interface; other site 216591022538 6 probable transmembrane helices predicted for BCAM0954 by TMHMM2.0 at aa 28-50, 204-226, 238-260, 287-309, 342-364 and 384-406 216591022539 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.00066 216591022540 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591022541 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022542 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 216591022543 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591022544 dimer interface [polypeptide binding]; other site 216591022545 conserved gate region; other site 216591022546 putative PBP binding loops; other site 216591022547 ABC-ATPase subunit interface; other site 216591022548 PS00430 TonB-dependent receptor proteins signature 1. 216591022549 6 probable transmembrane helices predicted for BCAM0955 by TMHMM2.0 at aa 20-42, 80-102, 114-136, 146-168, 189-211 and 243-265 216591022550 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2e-15 216591022551 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591022552 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591022553 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591022554 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591022555 13 probable transmembrane helices predicted for BCAM0956 by TMHMM2.0 at aa 21-43, 53-75, 87-109, 114-136, 143-165, 170-192, 205-227, 231-249, 269-291, 306-328, 335-357, 401-423 and 430-452 216591022556 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.7e-55 216591022557 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022558 Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377 216591022559 peptidase domain interface [polypeptide binding]; other site 216591022560 Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056 216591022561 active site 216591022562 catalytic triad [active] 216591022563 calcium binding site [ion binding]; other site 216591022564 HMMPfam hit to PF00082, Subtilase family, score 1.7e-23 216591022565 PS00138 Serine proteases, subtilase family, serine active site. 216591022566 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591022567 dimerization interface [polypeptide binding]; other site 216591022568 putative DNA binding site [nucleotide binding]; other site 216591022569 putative Zn2+ binding site [ion binding]; other site 216591022570 HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family, score 2.5e-11 216591022571 Predicted helix-turn-helix motif with score 1337.000, SD 3.74 at aa 30-51, sequence LTVAALTAHAGVSQPAVSKHLG 216591022572 Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814 216591022573 putative hydrophobic ligand binding site [chemical binding]; other site 216591022574 HMMPfam hit to PF08327, Activator of Hsp90 ATPase homolog 1-like pro, score 9.6e-17 216591022575 Domain of unknown function (DU1801); Region: DUF1801; cl17490 216591022576 aconitate hydratase; Provisional; Region: acnA; PRK12881 216591022577 Aconitase A catalytic domain; Region: AcnA_IRP; cd01586 216591022578 substrate binding site [chemical binding]; other site 216591022579 ligand binding site [chemical binding]; other site 216591022580 Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580 216591022581 substrate binding site [chemical binding]; other site 216591022582 HMMPfam hit to PF00694, Aconitase C-terminal domain, score 7.6e-52 216591022583 HMMPfam hit to PF00330, Aconitase family (aconitate hydratase), score 1e-186 216591022584 PS01244 Aconitase family signature 2. 216591022585 PS00450 Aconitase family signature 1. 216591022586 2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425 216591022587 2-methylcitrate dehydratase; Region: prpD; TIGR02330 216591022588 HMMPfam hit to PF03972, MmgE/PrpD family, score 2.6e-228 216591022589 1 probable transmembrane helix predicted for BCAM0963 by TMHMM2.0 at aa 4-26 216591022590 HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231 216591022591 HMMPfam hit to PF03328, HpcH/HpaI aldolase/citrate lyase family, score 4.3e-05 216591022592 PS00017 ATP/GTP-binding site motif A (P-loop). 216591022593 malate dehydrogenase; Provisional; Region: PRK05442 216591022594 Chloroplast-like malate dehydrogenases; Region: MDH_choloroplast_like; cd01338 216591022595 NAD(P) binding site [chemical binding]; other site 216591022596 dimer interface [polypeptide binding]; other site 216591022597 malate binding site [chemical binding]; other site 216591022598 HMMPfam hit to PF02866, lactate/malate dehydrogenase, alpha/beta C-t, score 1.6e-45 216591022599 HMMPfam hit to PF00056, lactate/malate dehydrogenase, NAD binding do, score 2.1e-54 216591022600 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 216591022601 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591022602 DNA-binding site [nucleotide binding]; DNA binding site 216591022603 The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866 216591022604 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 6.8e-26 216591022605 Predicted helix-turn-helix motif with score 1256.000, SD 3.46 at aa 67-88, sequence PSEVELAARYKVSQGTVRKAID 216591022606 HMMPfam hit to PF07702, UTRA domain, score 3.6e-34 216591022607 Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499 216591022608 Iron-sulfur protein interface; other site 216591022609 proximal quinone binding site [chemical binding]; other site 216591022610 SdhD (CybS) interface [polypeptide binding]; other site 216591022611 proximal heme binding site [chemical binding]; other site 216591022612 HMMPfam hit to PF01127, Succinate dehydrogenase cytochrome b subunit, score 1.6e-32 216591022613 3 probable transmembrane helices predicted for BCAM0967 by TMHMM2.0 at aa 32-54, 69-91 and 115-137 216591022614 Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494 216591022615 SdhC subunit interface [polypeptide binding]; other site 216591022616 proximal heme binding site [chemical binding]; other site 216591022617 cardiolipin binding site; other site 216591022618 Iron-sulfur protein interface; other site 216591022619 proximal quinone binding site [chemical binding]; other site 216591022620 HMMPfam hit to PF01127, Succinate dehydrogenase cytochrome b subunit, score 6.6e-05 216591022621 3 probable transmembrane helices predicted for BCAM0968 by TMHMM2.0 at aa 23-45, 55-77 and 98-120 216591022622 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022623 succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07057 216591022624 L-aspartate oxidase; Provisional; Region: PRK06175 216591022625 Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910 216591022626 HMMPfam hit to PF00890, FAD binding domain, score 1.1e-159 216591022627 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.0011 216591022628 PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 216591022629 HMMPfam hit to PF02910, Fumarate reductase/succinate dehydroge, score 5.7e-66 216591022630 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085 216591022631 succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950 216591022632 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591022633 HMMPfam hit to PF03937, TPR repeat region, score 4.1e-12 216591022634 Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114 216591022635 Citrate synthase [Energy production and conversion]; Region: GltA; COG0372 216591022636 dimer interface [polypeptide binding]; other site 216591022637 active site 216591022638 citrylCoA binding site [chemical binding]; other site 216591022639 NADH binding [chemical binding]; other site 216591022640 cationic pore residues; other site 216591022641 oxalacetate/citrate binding site [chemical binding]; other site 216591022642 coenzyme A binding site [chemical binding]; other site 216591022643 catalytic triad [active] 216591022644 HMMPfam hit to PF00285, Citrate synthase, score 1.3e-223 216591022645 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022646 PS00480 Citrate synthase signature. 216591022647 Cupin domain; Region: Cupin_2; cl17218 216591022648 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591022649 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591022650 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.5e-07 216591022651 PS00041 Bacterial regulatory proteins, araC family signature. 216591022652 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 4.2e-06 216591022653 Predicted helix-turn-helix motif with score 1414.000, SD 4.00 at aa 206-227, sequence LRIDALAAAAHMSERTLQRLFV 216591022654 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262 216591022655 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591022656 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 1.6e-10 216591022657 PS00190 Cytochrome c family heme-binding site signature. 216591022658 Protein of unknown function (DUF1479); Region: DUF1479; pfam07350 216591022659 HMMPfam hit to PF07350, Protein of unknown function (DUF1479), score 1.6e-208 216591022660 PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 216591022661 N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834 216591022662 Amidinotransferase; Region: Amidinotransf; cl12043 216591022663 HMMPfam hit to PF02274, Amidinotransferase, score 3.1e-17 216591022664 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591022665 Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412 216591022666 AsnC family; Region: AsnC_trans_reg; pfam01037 216591022667 HMMPfam hit to PF01037, AsnC family, score 2.1e-06 216591022668 lysine transporter; Provisional; Region: PRK10836 216591022669 HMMPfam hit to PF00324, Amino acid permease, score 1e-156 216591022670 12 probable transmembrane helices predicted for BCAM0978 by TMHMM2.0 at aa 27-46, 56-78, 99-121, 136-158, 165-187, 207-229, 250-272, 295-317, 348-370, 375-397, 418-440 and 450-472 216591022671 PS00218 Amino acid permeases signature. 216591022672 PS00435 Peroxidases proximal heme-ligand signature. 216591022673 GST_N family, Class Sigma_like; composed of GSTs belonging to class Sigma and similar proteins, including GSTs from class Mu, Pi and Alpha. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of...; Region: GST_N_Sigma_like; cd03039 216591022674 glutathione s-transferase; Provisional; Region: PTZ00057 216591022675 GSH binding site (G-site) [chemical binding]; other site 216591022676 C-terminal domain interface [polypeptide binding]; other site 216591022677 dimer interface [polypeptide binding]; other site 216591022678 C-terminal, alpha helical domain of Class Sigma-like Glutathione S-transferases; Region: GST_C_Sigma_like; cd03192 216591022679 dimer interface [polypeptide binding]; other site 216591022680 N-terminal domain interface [polypeptide binding]; other site 216591022681 substrate binding pocket (H-site) [chemical binding]; other site 216591022682 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 4.4e-10 216591022683 Cupin domain; Region: Cupin_2; cl17218 216591022684 HMMPfam hit to PF07883, Cupin domain, score 4e-05 216591022685 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022686 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022687 3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402 216591022688 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583 216591022689 substrate binding site [chemical binding]; other site 216591022690 ligand binding site [chemical binding]; other site 216591022691 HMMPfam hit to PF00330, Aconitase family (aconitate hydratase), score 2.4e-243 216591022692 PS00450 Aconitase family signature 1. 216591022693 PS01244 Aconitase family signature 2. 216591022694 Entericidin EcnA/B family; Region: Entericidin; cl02322 216591022695 HMMPfam hit to PF08085, Entericidin EcnA/B family, score 5.1e-11 216591022696 1 probable transmembrane helix predicted for BCAM0983A by TMHMM2.0 at aa 7-29 216591022697 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022698 isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641 216591022699 Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577 216591022700 substrate binding site [chemical binding]; other site 216591022701 HMMPfam hit to PF00694, Aconitase C-terminal domain, score 5e-59 216591022702 3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772 216591022703 tartrate dehydrogenase; Region: TTC; TIGR02089 216591022704 HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase, score 3.9e-196 216591022705 PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 216591022706 aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598 216591022707 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 216591022708 HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindi, score 7.9e-39 216591022709 HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisat, score 8.5e-70 216591022710 PS01103 Aspartate-semialdehyde dehydrogenase signature. 216591022711 flagellar hook protein FlgE; Validated; Region: flgE; PRK05682 216591022712 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 216591022713 Flagellar basal body protein FlaE; Region: FlaE; pfam07559 216591022714 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 216591022715 HMMPfam hit to PF06429, Domain of unknown function (DUF1078), score 4.7e-17 216591022716 HMMPfam hit to PF07559, Flagellar basal body protein FlaE, score 2.4e-16 216591022717 HMMPfam hit to PF00460, Flagella basal body rod protein, score 6.8e-10 216591022718 PS00588 Flagella basal body rod proteins signature. 216591022719 FimV N-terminal domain; Region: FimV_core; TIGR03505 216591022720 FimV C-terminal domain; Region: FimV_Cterm; TIGR03504 216591022721 tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021 216591022722 Eukaryotic and bacterial pseudouridine synthases similar to E. coli TruA; Region: PseudoU_synth_EcTruA; cd02570 216591022723 dimerization interface 3.5A [polypeptide binding]; other site 216591022724 active site 216591022725 HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 1.1e-29 216591022726 HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 2.2e-33 216591022727 Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405 216591022728 active site 216591022729 HMMPfam hit to PF00697, N-(5'phosphoribosyl)anthranilate (PRA) isome, score 6.6e-56 216591022730 tryptophan synthase, beta subunit; Region: trpB; TIGR00263 216591022731 Tryptophan synthase-beta: Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446 216591022732 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591022733 catalytic residue [active] 216591022734 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 1.1e-128 216591022735 PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 216591022736 DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863 216591022737 DNA methylase; Region: N6_N4_Mtase; pfam01555 216591022738 PS00228 Tubulin-beta mRNA autoregulation signal. 216591022739 HMMPfam hit to PF01555, DNA methylase, score 1e-70 216591022740 PS00092 N-6 Adenine-specific DNA methylases signature. 216591022741 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022742 tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200 216591022743 Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724 216591022744 substrate binding site [chemical binding]; other site 216591022745 active site 216591022746 catalytic residues [active] 216591022747 heterodimer interface [polypeptide binding]; other site 216591022748 HMMPfam hit to PF00290, Tryptophan synthase alpha chain, score 1.9e-103 216591022749 PS00167 Tryptophan synthase alpha chain signature. 216591022750 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591022751 PS00017 ATP/GTP-binding site motif A (P-loop). 216591022752 acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654 216591022753 malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682 216591022754 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022755 Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285 216591022756 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 216591022757 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 216591022758 HMMPfam hit to PF08245, Mur ligase middle domain, score 7.8e-07 216591022759 PS01011 Folylpolyglutamate synthase signature 1. 216591022760 Sporulation related domain; Region: SPOR; cl10051 216591022761 1 probable transmembrane helix predicted for BCAM0996 by TMHMM2.0 at aa 40-58 216591022762 HMMPfam hit to PF05036, Sporulation related domain, score 2.7e-12 216591022763 Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286 216591022764 Colicin V production protein; Region: Colicin_V; pfam02674 216591022765 HMMPfam hit to PF02674, Colicin V production protein, score 8.2e-28 216591022766 4 probable transmembrane helices predicted for BCAM0997 by TMHMM2.0 at aa 4-26, 33-55, 65-87 and 107-126 216591022767 amidophosphoribosyltransferase; Provisional; Region: PRK09246 216591022768 Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715 216591022769 active site 216591022770 tetramer interface [polypeptide binding]; other site 216591022771 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 216591022772 active site 216591022773 PS00443 Glutamine amidotransferases class-II active site. 216591022774 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 1.2e-39 216591022775 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.8e-13 216591022776 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 216591022777 O-succinylhomoserine sulfhydrylase; Validated; Region: PRK08133 216591022778 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 216591022779 homodimer interface [polypeptide binding]; other site 216591022780 substrate-cofactor binding pocket; other site 216591022781 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591022782 catalytic residue [active] 216591022783 HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 6.9e-200 216591022784 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.00044 216591022785 PS00070 Aldehyde dehydrogenases cysteine active site. 216591022786 PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 216591022787 Group II intron - IBS1 216591022788 Group II intron - EBS1 216591022789 Group II intron - EBS3 216591022790 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591022791 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591022792 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591022793 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 9.4e-37 216591022794 RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651 216591022795 Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078 216591022796 putative active site [active] 216591022797 putative NTP binding site [chemical binding]; other site 216591022798 putative nucleic acid binding site [nucleotide binding]; other site 216591022799 Group II intron, maturase-specific domain; Region: GIIM; pfam08388 216591022800 HMMPfam hit to PF00078, Reverse transcriptase (RNA-dependent DNA pol, score 1.9e-57 216591022801 HMMPfam hit to PF08388, Group II intron, maturase-specific domain, score 2e-24 216591022802 Group II intron - IBS3 216591022803 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 216591022804 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591022805 NAD(P) binding site [chemical binding]; other site 216591022806 active site 216591022807 HMMPfam hit to PF04321, RmlD substrate binding domain, score 8.5e-05 216591022808 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 1.8e-05 216591022809 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 1.1e-46 216591022810 HMMPfam hit to PF07993, Male sterility protein, score 3.7e-06 216591022811 GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089 216591022812 GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260 216591022813 NADP-binding site; other site 216591022814 homotetramer interface [polypeptide binding]; other site 216591022815 substrate binding site [chemical binding]; other site 216591022816 homodimer interface [polypeptide binding]; other site 216591022817 active site 216591022818 HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.0031 216591022819 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 1.1e-88 216591022820 PS00061 Short-chain dehydrogenases/reductases family signature. 216591022821 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 216591022822 HMMPfam hit to PF01757, Acyltransferase family, score 7.2e-38 216591022823 9 probable transmembrane helices predicted for BCAM1005 by TMHMM2.0 at aa 40-62, 83-105, 128-150, 155-177, 182-204, 211-233, 248-270, 283-305 and 311-333 216591022824 Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244 216591022825 Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128 216591022826 HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 1.5e-21 216591022827 12 probable transmembrane helices predicted for BCAM1007 by TMHMM2.0 at aa 9-31, 41-63, 84-106, 126-148, 161-178, 188-210, 223-241, 308-330, 342-364, 379-401, 421-443 and 453-475 216591022828 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591022829 This family is most closely related to the GT1 family of glycosyltransferases. wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea; Region: GT1_wbaZ_like; cd03804 216591022830 putative ADP-binding pocket [chemical binding]; other site 216591022831 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 216591022832 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591022833 HMMPfam hit to PF00534, Glycosyl transferases group, score 1.7e-31 216591022834 HMMPfam hit to PF00534, Glycosyl transferases group, score 3.7e-41 216591022835 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 216591022836 HMMPfam hit to PF01757, Acyltransferase family, score 3.6e-26 216591022837 10 probable transmembrane helices predicted for BCAM1009 by TMHMM2.0 at aa 27-46, 61-83, 114-136, 171-193, 200-217, 222-239, 252-274, 279-296, 308-330 and 340-359 216591022838 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022839 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022840 Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541 216591022841 active site 216591022842 tetramer interface; other site 216591022843 HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.2e-21 216591022844 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 216591022845 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 216591022846 HMMPfam hit to PF01757, Acyltransferase family, score 8.9e-16 216591022847 8 probable transmembrane helices predicted for BCAM1011 by TMHMM2.0 at aa 13-32, 37-54, 80-102, 160-182, 189-211, 221-240, 247-269 and 274-296 216591022848 HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 2.5e-08 216591022849 aminoglycoside resistance protein; Provisional; Region: PRK13746 216591022850 Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403 216591022851 active site 216591022852 NTP binding site [chemical binding]; other site 216591022853 metal binding triad [ion binding]; metal-binding site 216591022854 Domain of unknown function (DUF4111); Region: DUF4111; pfam13427 216591022855 HMMPfam hit to PF01909, Nucleotidyltransferase domain, score 2.8e-07 216591022856 Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588 216591022857 dimer interface [polypeptide binding]; other site 216591022858 HMMPfam hit to PF06983, 3-demethylubiquinone-9 3-methyltransfera, score 5.4e-51 216591022859 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022860 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591022861 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591022862 trimer interface [polypeptide binding]; other site 216591022863 eyelet of channel; other site 216591022864 HMMPfam hit to PF00267, Gram-negative porin, score 2.5e-07 216591022865 Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631 216591022866 HMMPfam hit to PF03631, Ribonuclease BN-like family, score 1.5e-45 216591022867 6 probable transmembrane helices predicted for BCAM1016 by TMHMM2.0 at aa 40-62, 107-129, 150-172, 187-209, 222-244 and 254-276 216591022868 formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553 216591022869 Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752 216591022870 [4Fe-4S] binding site [ion binding]; other site 216591022871 Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928 216591022872 Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752 216591022873 Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792 216591022874 molybdopterin cofactor binding site; other site 216591022875 HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 do, score 4.1e-24 216591022876 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 216591022877 HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 4.5e-19 216591022878 PS00215 Mitochondrial energy transfer proteins signature. 216591022879 HMMPfam hit to PF01568, Molydopterin dinucleotide binding dom, score 4e-12 216591022880 formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582 216591022881 4Fe-4S binding domain; Region: Fer4; cl02805 216591022882 Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163 216591022883 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 5.2e-06 216591022884 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591022885 Cytochrome b (N-terminus)/b6/petB: Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859 216591022886 formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583 216591022887 4 probable transmembrane helices predicted for BCAM1020 by TMHMM2.0 at aa 20-42, 57-79, 118-140 and 155-177 216591022888 formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562 216591022889 Protein involved in formate dehydrogenase formation; Region: FdhE; pfam04216 216591022890 HMMPfam hit to PF04216, Protein involved in formate dehydrogenase fo, score 8.1e-79 216591022891 selenocysteine synthase; Provisional; Region: PRK04311 216591022892 Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390 216591022893 Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921 216591022894 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591022895 catalytic residue [active] 216591022896 HMMPfam hit to PF03841, L-seryl-tRNA selenium transferase, score 4.4e-228 216591022897 HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 0.0051 216591022898 selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512 216591022899 SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171 216591022900 G1 box; other site 216591022901 putative GEF interaction site [polypeptide binding]; other site 216591022902 GTP/Mg2+ binding site [chemical binding]; other site 216591022903 Switch I region; other site 216591022904 G2 box; other site 216591022905 G3 box; other site 216591022906 Switch II region; other site 216591022907 G4 box; other site 216591022908 G5 box; other site 216591022909 selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696 216591022910 This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094 216591022911 Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106 216591022912 Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107 216591022913 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1e-31 216591022914 PS00017 ATP/GTP-binding site motif A (P-loop). 216591022915 PS00301 GTP-binding elongation factors signature. 216591022916 HMMPfam hit to PF03144, Elongation factor Tu domain, score 1.1e-14 216591022917 BcenGI12 216591022918 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 216591022919 active site 216591022920 catalytic residues [active] 216591022921 DNA binding site [nucleotide binding] 216591022922 Int/Topo IB signature motif; other site 216591022923 HMMPfam hit to PF00589, Phage integrase family, score 5.6e-12 216591022924 Predicted helix-turn-helix motif with score 1186.000, SD 3.23 at aa 20-41, sequence HTAREIATKLGTSTSFVQCFLD 216591022925 Protein of unknown function (DUF1643); Region: DUF1643; pfam07799 216591022926 HMMPfam hit to PF07799, Protein of unknown function (DUF1643), score 6.6e-16 216591022927 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591022928 non-specific DNA binding site [nucleotide binding]; other site 216591022929 salt bridge; other site 216591022930 sequence-specific DNA binding site [nucleotide binding]; other site 216591022931 HMMPfam hit to PF01381, Helix-turn-helix, score 3.4e-06 216591022932 Predicted helix-turn-helix motif with score 1425.000, SD 4.04 at aa 16-37, sequence MTLEDVADATGSSKSYVWELES 216591022933 Methyltransferase domain; Region: Methyltransf_25; pfam13649 216591022934 YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588 216591022935 1 probable transmembrane helix predicted for BCAM1042 by TMHMM2.0 at aa 20-42 216591022936 1 probable transmembrane helix predicted for BCAM1043 by TMHMM2.0 at aa 25-47 216591022937 PS00011 Vitamin K-dependent carboxylation domain. 216591022938 Fic/DOC family; Region: Fic; cl00960 216591022939 HMMPfam hit to PF05012, Prophage maintenance system killer protein, score 1.5e-32 216591022940 RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651 216591022941 Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078 216591022942 putative active site [active] 216591022943 putative NTP binding site [chemical binding]; other site 216591022944 putative nucleic acid binding site [nucleotide binding]; other site 216591022945 HMMPfam hit to PF00078, Reverse transcriptase (RNA-dependent DNA pol, score 1.5e-62 216591022946 EBS1? 216591022947 Group II intron - EBS2 216591022948 IBS1 216591022949 IBS2 216591022950 Predicted helix-turn-helix motif with score 1076.000, SD 2.85 at aa 21-42, sequence GGAAHIAREIGKEPNYISRALY 216591022951 Predicted helix-turn-helix motif with score 1105.000, SD 2.95 at aa 17-38, sequence PDRKRAAEALGWDPSEVSRFLN 216591022952 Protein of unknown function (DUF1376); Region: DUF1376; cl01531 216591022953 PS00294 Prenyl group binding site (CAAX box). 216591022954 Endodeoxyribonuclease RusA; Region: RusA; pfam05866 216591022955 HMMPfam hit to PF05866, Endodeoxyribonuclease RusA, score 6.5e-21 216591022956 Predicted helix-turn-helix motif with score 1439.000, SD 4.09 at aa 23-44, sequence YTAHDLARSAGVPLSTVRHLLA 216591022957 Predicted helix-turn-helix motif with score 1307.000, SD 3.64 at aa 106-127, sequence LTRASAAYCSGFSHYRVRRAII 216591022958 Predicted helix-turn-helix motif with score 1307.000, SD 3.64 at aa 135-156, sequence CDLSEIADECGAHRNTVSKQNA 216591022959 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410 216591022960 Terminase-like family; Region: Terminase_6; pfam03237 216591022961 Phage-related terminase [General function prediction only]; Region: COG5362; cl02216 216591022962 HMMPfam hit to PF03237, Terminase-like family, score 1.3e-68 216591022963 phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555 216591022964 Protein of unknown function (DUF1073); Region: DUF1073; pfam06381 216591022965 Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072 216591022966 HMMPfam hit to PF04233, Phage Mu protein F like protein, score 1.7e-06 216591022967 Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979 216591022968 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4834 216591022969 Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950 216591022970 1 probable transmembrane helix predicted for BCAM1068 by TMHMM2.0 at aa 7-24 216591022971 PS00017 ATP/GTP-binding site motif A (P-loop). 216591022972 Protein of unknown function (DUF4054); Region: DUF4054; pfam13262 216591022973 Protein of unknown function (DUF3383); Region: DUF3383; pfam11863 216591022974 PS00962 Ribosomal protein S2 signature 1. 216591022975 Protein of unknown function (DUF3277); Region: DUF3277; pfam11681 216591022976 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832 216591022977 PS00017 ATP/GTP-binding site motif A (P-loop). 216591022978 HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 9e-11 216591022979 3 probable transmembrane helices predicted for BCAM1081 by TMHMM2.0 at aa 25-47, 57-79 and 134-156 216591022980 PS00216 Sugar transport proteins signature 1. 216591022981 Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; cl15410 216591022982 1 probable transmembrane helix predicted for BCAM1083 by TMHMM2.0 at aa 212-234 216591022983 Protein of unknown function (DUF2612); Region: DUF2612; pfam11041 216591022984 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022985 Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708 216591022986 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022987 1 probable transmembrane helix predicted for BCAM1091 by TMHMM2.0 at aa 87-109 216591022988 lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222 216591022989 catalytic residue [active] 216591022990 HMMPfam hit to PF00182, Chitinase class I, score 0.00061 216591022991 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591022992 Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883 216591022993 nucleophilic elbow; other site 216591022994 catalytic triad; other site 216591022995 HMMPfam hit to PF01764, Lipase (class 3), score 3.9e-15 216591022996 PS00120 Lipases, serine active site. 216591022997 2 probable transmembrane helices predicted for BCAM1097 by TMHMM2.0 at aa 19-41 and 51-68 216591022998 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_10; cd04667 216591022999 nudix motif; other site 216591023000 HMMPfam hit to PF00293, NUDIX domain, score 8.2e-25 216591023001 PS00893 mutT domain signature. 216591023002 xanthine permease; Region: pbuX; TIGR03173 216591023003 12 probable transmembrane helices predicted for BCAM1099 by TMHMM2.0 at aa 12-31, 36-53, 58-80, 95-117, 124-146, 161-180, 185-207, 227-249, 317-336, 346-368, 375-392 and 407-426 216591023004 HMMPfam hit to PF00860, Permease family, score 1.6e-119 216591023005 PS01116 Xanthine/uracil permeases family signature. 216591023006 PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 216591023007 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591023008 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023009 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_1; cd08460 216591023010 putative substrate binding pocket [chemical binding]; other site 216591023011 putative dimerization interface [polypeptide binding]; other site 216591023012 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.3e-16 216591023013 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.8e-14 216591023014 PS00044 Bacterial regulatory proteins, lysR family signature. 216591023015 Predicted helix-turn-helix motif with score 1154.000, SD 3.12 at aa 19-40, sequence SSVTGAARRLGLSTSAMSRTLT 216591023016 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591023017 C factor cell-cell signaling protein; Provisional; Region: PRK09009 216591023018 NAD(P) binding site [chemical binding]; other site 216591023019 active site 216591023020 HMMPfam hit to PF00106, short chain dehydrogenase, score 4.8e-07 216591023021 Contains amber stop codon at codon 374. Similar to Ralstonia metallidurans major facilitator superfamily mfs_1 UniProt:Q1LC21 (EMBL:CP000353 (484 aa) fasta scores: E()=2e-136, 78.306% id in 484 aa 216591023022 HMMPfam hit to PF00083, Sugar (and other) transporter score 5.2e-06 216591023023 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4e-33 216591023024 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 216591023025 Glycerol kinase [Energy production and conversion]; Region: GlpK; COG0554 216591023026 nucleotide binding site [chemical binding]; other site 216591023027 HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 6.5e-31 216591023028 HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 2.8e-27 216591023029 PS00445 FGGY family of carbohydrate kinases signature 2. 216591023030 Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578 216591023031 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 216591023032 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.5e-52 216591023033 glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387 216591023034 FAD binding domain; Region: FAD_binding_4; pfam01565 216591023035 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591023036 HMMPfam hit to PF01565, FAD binding domain, score 5.6e-38 216591023037 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023038 HMMPfam hit to PF02913, FAD linked oxidases, C-terminal domain, score 7.8e-29 216591023039 Glycerol-3-phosphate responsive antiterminator; Region: G3P_antiterm; cl00852 216591023040 HMMPfam hit to PF04309, Glycerol-3-phosphate responsive antiterm, score 1.4e-14 216591023041 Uncharacterized conserved protein [Function unknown]; Region: COG1359 216591023042 HMMPfam hit to PF03992, Antibiotic biosynthesis monooxygenase, score 3.1e-19 216591023043 5-hydroxyvalerate dehydrogenase (HVD) catalyzes the oxidation of 5-hydroxyvalerate to 5-oxovalerate with NAD+ as cofactor; Region: HVD; cd08193 216591023044 Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454 216591023045 putative active site [active] 216591023046 metal binding site [ion binding]; metal-binding site 216591023047 HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 9.3e-88 216591023048 PS00913 Iron-containing alcohol dehydrogenases signature 1. 216591023049 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591023050 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591023051 putative substrate translocation pore; other site 216591023052 12 probable transmembrane helices predicted for BCAM1110 by TMHMM2.0 at aa 7-29, 44-63, 70-89, 94-116, 129-148, 153-175, 203-225, 235-257, 270-289, 294-316, 328-350 and 355-377 216591023053 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023054 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.2e-38 216591023055 ornithine decarboxylase; Provisional; Region: PRK13578 216591023056 Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709 216591023057 Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615 216591023058 homodimer interface [polypeptide binding]; other site 216591023059 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591023060 catalytic residue [active] 216591023061 Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711 216591023062 HMMPfam hit to PF03711, Orn/Lys/Arg decarboxylase, C-terminal doma, score 8.4e-79 216591023063 HMMPfam hit to PF01276, Orn/Lys/Arg decarboxylase, major domain, score 1.1e-279 216591023064 PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 216591023065 HMMPfam hit to PF03709, Orn/Lys/Arg decarboxylase, N-terminal doma, score 1.2e-14 216591023066 arginine decarboxylase; Provisional; Region: PRK15029 216591023067 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591023068 active site 216591023069 phosphorylation site [posttranslational modification] 216591023070 intermolecular recognition site; other site 216591023071 dimerization interface [polypeptide binding]; other site 216591023072 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 216591023073 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591023074 catalytic residue [active] 216591023075 Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711 216591023076 HMMPfam hit to PF00072, Response regulator receiver domain, score 0.0015 216591023077 HMMPfam hit to PF03709, Orn/Lys/Arg decarboxylase, N-terminal do, score 6.5e-22 216591023078 HMMPfam hit to PF01276, Orn/Lys/Arg decarboxylase, major domain, score 3.3e-215 216591023079 PS00445 FGGY family of carbohydrate kinases signature 2. 216591023080 PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 216591023081 HMMPfam hit to PF03711, Orn/Lys/Arg decarboxylase, C-terminal do, score 1.1e-61 216591023082 putrescine transporter; Provisional; Region: potE; PRK10655 216591023083 12 probable transmembrane helices predicted for BCAM1113 by TMHMM2.0 at aa 21-43, 48-70, 103-125, 135-154, 161-183, 198-217, 238-260, 280-302, 334-353, 363-385, 397-416 and 421-443 216591023084 HMMPfam hit to PF00324, Amino acid permease, score 9e-06 216591023085 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023086 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591023087 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023088 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591023089 putative effector binding pocket; other site 216591023090 dimerization interface [polypeptide binding]; other site 216591023091 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.3e-34 216591023092 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.3e-11 216591023093 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 216591023094 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591023095 trimer interface [polypeptide binding]; other site 216591023096 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591023097 Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295 216591023098 Haemagglutinin; Region: HIM; pfam05662 216591023099 Haemagglutinin; Region: HIM; pfam05662 216591023100 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591023101 YadA-like C-terminal region; Region: YadA; pfam03895 216591023102 HMMPfam hit to PF05658, Hep_Hag, score 0.00016 216591023103 HMMPfam hit to PF05658, Hep_Hag, score 0.0017 216591023104 HMMPfam hit to PF05658, Hep_Hag, score 0.00034 216591023105 HMMPfam hit to PF05662, Haemagglutinin, score 4.7e-07 216591023106 HMMPfam hit to PF05662, Haemagglutinin, score 1.8e-05 216591023107 HMMPfam hit to PF05662, Haemagglutinin, score 9.3e-06 216591023108 HMMPfam hit to PF05662, Haemagglutinin, score 2.6e-07 216591023109 HMMPfam hit to PF05658, Hep_Hag, score 1.5e-05 216591023110 HMMPfam hit to PF05662, Haemagglutinin, score 2.9e-07 216591023111 PS00017 ATP/GTP-binding site motif A (P-loop). 216591023112 HMMPfam hit to PF05662, Haemagglutinin, score 2.7e-07 216591023113 HMMPfam hit to PF05658, Hep_Hag, score 7.8e-05 216591023114 HMMPfam hit to PF05662, Haemagglutinin, score 9.7e-08 216591023115 HMMPfam hit to PF05662, Haemagglutinin, score 5.9e-08 216591023116 HMMPfam hit to PF05658, Hep_Hag, score 0.0054 216591023117 HMMPfam hit to PF05662, Haemagglutinin, score 1.2e-05 216591023118 HMMPfam hit to PF05658, Hep_Hag, score 0.016 216591023119 HMMPfam hit to PF05658, Hep_Hag, score 2.7e-05 216591023120 HMMPfam hit to PF05662, Haemagglutinin, score 5.2e-07 216591023121 HMMPfam hit to PF03895, YadA-like C-terminal region, score 1.5e-34 216591023122 Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913 216591023123 SmpA / OmlA family; Region: SmpA_OmlA; pfam04355 216591023124 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023125 HMMPfam hit to PF04355, SmpA / OmlA family, score 1.9e-30 216591023126 Putative glycolipid-binding; Region: Glycolipid_bind; pfam06475 216591023127 HMMPfam hit to PF06475, Protein of unknown function (DUF1089), score 8.8e-31 216591023128 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 216591023129 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591023130 substrate binding pocket [chemical binding]; other site 216591023131 membrane-bound complex binding site; other site 216591023132 hinge residues; other site 216591023133 1 probable transmembrane helix predicted for BCAM1118 by TMHMM2.0 at aa 21-43 216591023134 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2343 216591023135 HMMPfam hit to PF04248, Domain of unknown function (DUF427), score 2.9e-40 216591023136 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 216591023137 The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493 216591023138 peptide binding site [polypeptide binding]; other site 216591023139 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 5.5e-84 216591023140 PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 216591023141 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 216591023142 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 216591023143 HMMPfam hit to PF02668, Taurine catabolism dioxygenase TauD, TfdA fa, score 5.8e-94 216591023144 PS00092 N-6 Adenine-specific DNA methylases signature. 216591023145 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 216591023146 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 216591023147 HMMPfam hit to PF02668, Taurine catabolism dioxygenase TauD, TfdA fa, score 1.1e-108 216591023148 Predicted helix-turn-helix motif with score 1027.000, SD 2.68 at aa 233-254, sequence LSAQDSAHLLQVFHEHVTRLEN 216591023149 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 216591023150 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 216591023151 Walker A/P-loop; other site 216591023152 ATP binding site [chemical binding]; other site 216591023153 Q-loop/lid; other site 216591023154 ABC transporter signature motif; other site 216591023155 Walker B; other site 216591023156 D-loop; other site 216591023157 H-loop/switch region; other site 216591023158 HMMPfam hit to PF00005, ABC transporter score 1.3e-55 216591023159 PS00211 ABC transporters family signature. 216591023160 PS00017 ATP/GTP-binding site motif A (P-loop). 216591023161 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591023162 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591023163 dimer interface [polypeptide binding]; other site 216591023164 putative PBP binding loops; other site 216591023165 ABC-ATPase subunit interface; other site 216591023166 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.6e-19 216591023167 5 probable transmembrane helices predicted for BCAM1124 by TMHMM2.0 at aa 24-46, 84-106, 121-143, 184-206 and 236-258 216591023168 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591023169 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591023170 ABC-ATPase subunit interface; other site 216591023171 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.5e-27 216591023172 7 probable transmembrane helices predicted for BCAM1125 by TMHMM2.0 at aa 29-51, 90-109, 124-143, 150-168, 188-210, 215-234 and 244-263 216591023173 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591023174 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432 216591023175 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 216591023176 Protein of unknown function (DUF2029); Region: DUF2029; pfam09594 216591023177 8 probable transmembrane helices predicted for BCAM1127 by TMHMM2.0 at aa 25-47, 122-144, 156-178, 198-220, 227-249, 290-312, 341-360 and 380-402 216591023178 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714 216591023179 Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187 216591023180 Ligand binding site; other site 216591023181 Putative Catalytic site; other site 216591023182 DXD motif; other site 216591023183 2 probable transmembrane helices predicted for BCAM1128 by TMHMM2.0 at aa 235-257 and 272-294 216591023184 HMMPfam hit to PF00535, Glycosyl transferase family, score 3.6e-22 216591023185 Protein of unknown function (DUF2591); Region: DUF2591; cl11584 216591023186 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432 216591023187 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591023188 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023189 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 216591023190 dimerization interface [polypeptide binding]; other site 216591023191 substrate binding pocket [chemical binding]; other site 216591023192 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.3e-23 216591023193 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.1e-18 216591023194 Predicted helix-turn-helix motif with score 1411.000, SD 3.99 at aa 19-40, sequence LHFARAAEALDMAPPALTRQIQ 216591023195 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591023196 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591023197 putative substrate translocation pore; other site 216591023198 14 probable transmembrane helices predicted for BCAM1132 by TMHMM2.0 at aa 26-48, 63-85, 92-114, 118-140, 153-175, 180-202, 215-234, 239-261, 281-303, 318-340, 345-367, 371-390, 417-439 and 493-515 216591023199 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.1e-54 216591023200 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023201 PS00216 Sugar transport proteins signature 1. 216591023202 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591023203 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023204 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591023205 dimerization interface [polypeptide binding]; other site 216591023206 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.4e-21 216591023207 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.2e-19 216591023208 Predicted helix-turn-helix motif with score 1188.000, SD 3.23 at aa 39-60, sequence RTVSRAAVRLNMSQPATSAALK 216591023209 Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518 216591023210 HMMPfam hit to PF01177, Asp/Glu/Hydantoin racemase, score 7.9e-06 216591023211 uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain; Region: SLC-NCS1sbd_u1; cd11555 216591023212 Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133 216591023213 Na binding site [ion binding]; other site 216591023214 putative substrate binding site [chemical binding]; other site 216591023215 11 probable transmembrane helices predicted for BCAM1135 by TMHMM2.0 at aa 80-102, 122-144, 172-194, 207-224, 244-266, 279-301, 334-356, 369-386, 390-412, 446-468 and 472-489 216591023216 HMMPfam hit to PF02133, Permease for cytosine/purines, uracil,, score 9.1e-69 216591023217 Protein of unknown function (DUF3005); Region: DUF3005; pfam11448 216591023218 Domain of unknown function (DUF4397); Region: DUF4397; pfam14344 216591023219 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023220 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591023221 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591023222 putative substrate translocation pore; other site 216591023223 12 probable transmembrane helices predicted for BCAM1138 by TMHMM2.0 at aa 24-41, 64-86, 93-112, 118-140, 152-174, 184-206, 254-276, 286-308, 320-337, 342-364, 377-399 and 409-428 216591023224 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.9e-48 216591023225 MarR family; Region: MarR_2; cl17246 216591023226 Transcriptional regulators [Transcription]; Region: MarR; COG1846 216591023227 HMMPfam hit to PF01047, MarR family, score 8.6e-08 216591023228 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591023229 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 216591023230 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591023231 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 216591023232 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591023233 HMMPfam hit to PF02738, Aldehyde oxidase and xanthine dehydroge, score 1e-07 216591023234 PS00030 Eukaryotic putative RNA-binding region RNP-1 signature. 216591023235 HMMPfam hit to PF01315, Aldehyde oxidase and xanthine dehydroge, score 0.00098 216591023236 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220 216591023237 Isochorismatase family; Region: Isochorismatase; pfam00857 216591023238 catalytic triad [active] 216591023239 conserved cis-peptide bond; other site 216591023240 HMMPfam hit to PF00857, Isochorismatase family, score 2.5e-09 216591023241 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591023242 Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309 216591023243 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591023244 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 4.3e-17 216591023245 Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518 216591023246 HMMPfam hit to PF01177, Asp/Glu/Hydantoin racemase, score 3.2e-27 216591023247 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591023248 HMMPfam hit to PF01494, FAD binding domain, score 3.2e-09 216591023249 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.0017 216591023250 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080 216591023251 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2; pfam00111 216591023252 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 216591023253 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 3.9e-07 216591023254 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591023255 HMMPfam hit to PF01799, [2Fe-2S] binding domain, score 2.6e-30 216591023256 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591023257 Cytochrome c; Region: Cytochrom_C; pfam00034 216591023258 PS00190 Cytochrome c family heme-binding site signature. 216591023259 PS00190 Cytochrome c family heme-binding site signature. 216591023260 HMMPfam hit to PF00034, Cytochrome c, score 0.0016 216591023261 PS00190 Cytochrome c family heme-binding site signature. 216591023262 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023263 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 216591023264 3-hydroxyisobutyrate dehydrogenase; Region: HIBADH; TIGR01692 216591023265 HMMPfam hit to PF03446, NAD binding domain of 6-phosphoglucona, score 1e-72 216591023266 HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 0.0028 216591023267 PS00895 3-hydroxyisobutyrate dehydrogenase signature. 216591023268 Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085 216591023269 methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722 216591023270 tetrameric interface [polypeptide binding]; other site 216591023271 NAD binding site [chemical binding]; other site 216591023272 catalytic residues [active] 216591023273 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 7.8e-182 216591023274 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591023275 PS00070 Aldehyde dehydrogenases cysteine active site. 216591023276 shikimate transporter; Provisional; Region: PRK09952 216591023277 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591023278 putative substrate translocation pore; other site 216591023279 HMMPfam hit to PF00083, Sugar (and other) transporter score 5.9e-21 216591023280 12 probable transmembrane helices predicted for BCAM1152 by TMHMM2.0 at aa 43-60, 71-93, 100-119, 134-156, 168-190, 200-219, 258-280, 290-312, 321-338, 348-370, 383-405 and 415-437 216591023281 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.9e-23 216591023282 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591023283 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591023284 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023285 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591023286 dimerization interface [polypeptide binding]; other site 216591023287 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.1e-16 216591023288 Predicted helix-turn-helix motif with score 992.000, SD 2.57 at aa 43-64, sequence QRASGAAKRLGVDYTTVARRIR 216591023289 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.3e-36 216591023290 5 probable transmembrane helices predicted for BCAM1154 by TMHMM2.0 at aa 4-26, 43-65, 159-181, 194-216 and 231-253 216591023291 2-haloalkanoic acid dehalogenase, type II; Region: HAD_type_II; TIGR01428 216591023292 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591023293 motif II; other site 216591023294 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1e-17 216591023295 Isochorismatase family; Region: Isochorismatase; pfam00857 216591023296 YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012 216591023297 catalytic triad [active] 216591023298 dimer interface [polypeptide binding]; other site 216591023299 conserved cis-peptide bond; other site 216591023300 HMMPfam hit to PF00857, Isochorismatase family, score 1.4e-08 216591023301 LysR family transcriptional regulator; Provisional; Region: PRK14997 216591023302 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023303 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473 216591023304 putative effector binding pocket; other site 216591023305 putative dimerization interface [polypeptide binding]; other site 216591023306 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.1e-18 216591023307 Predicted helix-turn-helix motif with score 1591.000, SD 4.61 at aa 22-43, sequence GGFTQAGRALDVPKSTLSRRIA 216591023308 PS00044 Bacterial regulatory proteins, lysR family signature. 216591023309 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.8e-41 216591023310 Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119 216591023311 Sulfatase; Region: Sulfatase; cl17466 216591023312 HMMPfam hit to PF00884, Sulfatase, score 6.6e-17 216591023313 pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424 216591023314 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023315 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591023316 dimerization interface [polypeptide binding]; other site 216591023317 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.8e-18 216591023318 Predicted helix-turn-helix motif with score 1679.000, SD 4.91 at aa 51-72, sequence RSFARTSEAASITQPALSKWLR 216591023319 PS00044 Bacterial regulatory proteins, lysR family signature. 216591023320 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.2e-21 216591023321 FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203 216591023322 GAF domain; Region: GAF; pfam01590 216591023323 PAS fold; Region: PAS; pfam00989 216591023324 PAS domain; Region: PAS; smart00091 216591023325 putative active site [active] 216591023326 heme pocket [chemical binding]; other site 216591023327 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591023328 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591023329 metal binding site [ion binding]; metal-binding site 216591023330 active site 216591023331 I-site; other site 216591023332 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 216591023333 HMMPfam hit to PF01590, GAF domain, score 3.2e-11 216591023334 HMMPfam hit to PF00989, PAS fold, score 0.00059 216591023335 HMMPfam hit to PF00990, GGDEF domain, score 1.2e-52 216591023336 HMMPfam hit to PF00563, EAL domain, score 2.4e-125 216591023337 Response regulator receiver domain; Region: Response_reg; pfam00072 216591023338 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591023339 active site 216591023340 phosphorylation site [posttranslational modification] 216591023341 intermolecular recognition site; other site 216591023342 dimerization interface [polypeptide binding]; other site 216591023343 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591023344 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591023345 metal binding site [ion binding]; metal-binding site 216591023346 active site 216591023347 I-site; other site 216591023348 HMMPfam hit to PF00990, GGDEF domain, score 1.8e-63 216591023349 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.7e-14 216591023350 chemotaxis-specific methylesterase; Provisional; Region: PRK12555 216591023351 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591023352 active site 216591023353 phosphorylation site [posttranslational modification] 216591023354 intermolecular recognition site; other site 216591023355 CheB methylesterase; Region: CheB_methylest; pfam01339 216591023356 HMMPfam hit to PF01339, CheB methylesterase, score 4.9e-66 216591023357 HMMPfam hit to PF00072, Response regulator receiver domain, score 4.9e-13 216591023358 Protein of unknown function (DUF969); Region: DUF969; pfam06149 216591023359 HMMPfam hit to PF06149, Protein of unknown function (DUF969), score 1.3e-136 216591023360 4 probable transmembrane helices predicted for BCAM1165 by TMHMM2.0 at aa 13-35, 55-74, 94-116 and 190-212 216591023361 Predicted membrane protein [Function unknown]; Region: COG3817 216591023362 Protein of unknown function (DUF979); Region: DUF979; pfam06166 216591023363 HMMPfam hit to PF06166, Protein of unknown function (DUF979), score 3.2e-166 216591023364 8 probable transmembrane helices predicted for BCAM1166 by TMHMM2.0 at aa 7-24, 44-66, 95-117, 127-149, 170-192, 207-229, 250-272 and 295-314 216591023365 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023366 Protein of unknown function (DUF2891); Region: DUF2891; pfam11199 216591023367 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591023368 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 216591023369 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591023370 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 3.5e-25 216591023371 HMMPfam hit to PF08279, HTH domain, score 0.0043 216591023372 Predicted helix-turn-helix motif with score 1455.000, SD 4.14 at aa 36-57, sequence YTLSQLAARLHIPKATLLRLIE 216591023373 choline dehydrogenase; Validated; Region: PRK02106 216591023374 putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834 216591023375 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 216591023376 HMMPfam hit to PF00732, GMC oxidoreductase, score 2.3e-108 216591023377 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023378 PS00624 GMC oxidoreductases signature 2. 216591023379 HMMPfam hit to PF05199, GMC oxidoreductase, score 7.6e-49 216591023380 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591023381 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591023382 putative substrate translocation pore; other site 216591023383 HMMPfam hit to PF00083, Sugar (and other) transporter score 7e-11 216591023384 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.9e-15 216591023385 12 probable transmembrane helices predicted for BCAM1171 by TMHMM2.0 at aa 5-27, 42-64, 73-95, 110-132, 139-161, 171-193, 232-254, 264-286, 293-315, 320-339, 360-382 and 386-405 216591023386 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591023387 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591023388 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 6.7e-68 216591023389 gamma-aminobutyrate permease; Region: GABAperm; TIGR01773 216591023390 HMMPfam hit to PF00324, Amino acid permease, score 6.6e-130 216591023391 12 probable transmembrane helices predicted for BCAM1173 by TMHMM2.0 at aa 21-40, 44-66, 95-117, 132-154, 166-188, 203-225, 248-270, 285-307, 338-360, 365-387, 408-430 and 437-454 216591023392 PS00218 Amino acid permeases signature. 216591023393 Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243 216591023394 Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928 216591023395 molybdopterin cofactor binding site; other site 216591023396 Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928 216591023397 Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243 216591023398 The MopB_CT_2 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. This CD is...; Region: MopB_CT_2; cd02783 216591023399 putative molybdopterin cofactor binding site; other site 216591023400 HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 do, score 1.2e-18 216591023401 HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 2.6e-27 216591023402 Predicted helix-turn-helix motif with score 1005.000, SD 2.61 at aa 338-359, sequence CTPEWAADITGIAADTIRRLAR 216591023403 PS00215 Mitochondrial energy transfer proteins signature. 216591023404 HMMPfam hit to PF01568, Molydopterin dinucleotide binding dom, score 3e-09 216591023405 Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437 216591023406 4Fe-4S binding domain; Region: Fer4; pfam00037 216591023407 PS00190 Cytochrome c family heme-binding site signature. 216591023408 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 9.1e-09 216591023409 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591023410 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023411 DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519 216591023412 HMMPfam hit to PF04976, DMSO reductase anchor subunit (DmsC), score 6.4e-12 216591023413 8 probable transmembrane helices predicted for BCAM1176 by TMHMM2.0 at aa 7-29, 44-66, 87-109, 114-136, 149-171, 175-197, 251-273 and 278-300 216591023414 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023415 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023416 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591023417 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 216591023418 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591023419 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 5e-32 216591023420 Predicted helix-turn-helix motif with score 1134.000, SD 3.05 at aa 25-46, sequence VSLADLARDVDIPKASLHRMLA 216591023421 Cobaltochelatase CobS subunit N terminal; Region: CobS_N; pfam12556 216591023422 cobaltochelatase, CobS subunit; Region: PD_CobS; TIGR01650 216591023423 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189 216591023424 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 0.00024 216591023425 HMMPfam hit to PF07726, ATPase family associated with various cellul, score 8.1e-05 216591023426 PS00017 ATP/GTP-binding site motif A (P-loop). 216591023427 Cobalamin biosynthesis protein CobT; Region: CobT; pfam06213 216591023428 Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057 216591023429 metal ion-dependent adhesion site (MIDAS); other site 216591023430 HMMPfam hit to PF06213, Cobalamin biosynthesis protein CobT, score 1.9e-19 216591023431 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 216591023432 8 probable transmembrane helices predicted for BCAM1180 by TMHMM2.0 at aa 7-29, 39-61, 73-92, 102-121, 134-156, 166-188, 197-216 and 231-253 216591023433 HMMPfam hit to PF01925, Domain of unknown function DUF81, score 4.8e-07 216591023434 Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212 216591023435 HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 3.2e-132 216591023436 sulfoacetaldehyde acetyltransferase; Validated; Region: PRK07525 216591023437 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 216591023438 PYR/PP interface [polypeptide binding]; other site 216591023439 dimer interface [polypeptide binding]; other site 216591023440 TPP binding site [chemical binding]; other site 216591023441 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591023442 Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the...; Region: TPP_Xsc_like; cd02013 216591023443 TPP-binding site; other site 216591023444 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 4e-49 216591023445 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 1.2e-26 216591023446 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 4.4e-36 216591023447 SnoaL-like domain; Region: SnoaL_2; pfam12680 216591023448 HMMPfam hit to PF07366, SnoaL-like polyketide cyclase, score 9.3e-07 216591023449 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591023450 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591023451 DNA-binding site [nucleotide binding]; DNA binding site 216591023452 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591023453 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591023454 homodimer interface [polypeptide binding]; other site 216591023455 catalytic residue [active] 216591023456 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.8e-05 216591023457 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 8.8e-18 216591023458 Predicted helix-turn-helix motif with score 1035.000, SD 2.71 at aa 46-67, sequence PSSRELADQLGVARNTVVLAYQ 216591023459 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591023460 Coenzyme A binding pocket [chemical binding]; other site 216591023461 putative phosphonoacetaldehyde dehydrogenase; Region: PhnAcAld_DH; TIGR03250 216591023462 Streptomyces putative phosphonoformaldehyde dehydrogenase PhpJ-like; Region: ALDH_PhpJ; cd07146 216591023463 NAD(P) binding site [chemical binding]; other site 216591023464 catalytic residues [active] 216591023465 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 2.2e-179 216591023466 PS00017 ATP/GTP-binding site motif A (P-loop). 216591023467 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591023468 PS00070 Aldehyde dehydrogenases cysteine active site. 216591023469 Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; Region: Fiu; COG4774 216591023470 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591023471 N-terminal plug; other site 216591023472 ligand-binding site [chemical binding]; other site 216591023473 HMMPfam hit to PF00593, TonB dependent receptor, score 1.2e-30 216591023474 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 5e-21 216591023475 L-asparaginase II; Region: Asparaginase_II; pfam06089 216591023476 HMMPfam hit to PF06089, L-asparaginase II, score 2e-142 216591023477 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023478 transcriptional activator TtdR; Provisional; Region: PRK09801 216591023479 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591023480 putative effector binding pocket; other site 216591023481 dimerization interface [polypeptide binding]; other site 216591023482 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.2e-38 216591023483 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.4e-16 216591023484 PS00044 Bacterial regulatory proteins, lysR family signature. 216591023485 Predicted helix-turn-helix motif with score 1748.000, SD 5.14 at aa 26-47, sequence GSFSAVAKEMHVSTSTVARKVT 216591023486 aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273 216591023487 Aspartase; Region: Aspartase; cd01357 216591023488 active sites [active] 216591023489 tetramer interface [polypeptide binding]; other site 216591023490 HMMPfam hit to PF00206, Lyase, score 5.8e-153 216591023491 PS00163 Fumarate lyases signature. 216591023492 Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113 216591023493 HMMPfam hit to PF00324, Amino acid permease, score 3.3e-143 216591023494 12 probable transmembrane helices predicted for BCAM1191 by TMHMM2.0 at aa 42-61, 71-93, 114-136, 151-173, 178-200, 226-248, 269-291, 306-328, 358-380, 384-406, 427-449 and 453-475 216591023495 PS00218 Amino acid permeases signature. 216591023496 putative hydrolase; Provisional; Region: PRK11460 216591023497 HMMPfam hit to PF02230, Phospholipase/Carboxylesterase, score 1.7e-07 216591023498 Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456 216591023499 HMMPfam hit to PF04014, SpoVT / AbrB like domain, score 2.6e-05 216591023500 PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881 216591023501 oligomeric interface; other site 216591023502 putative active site [active] 216591023503 homodimer interface [polypeptide binding]; other site 216591023504 HMMPfam hit to PF01850, PIN domain, score 1.2e-20 216591023505 Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729 216591023506 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591023507 dimerization interface [polypeptide binding]; other site 216591023508 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Region: PAC; smart00086 216591023509 Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088 216591023510 putative binding surface; other site 216591023511 active site 216591023512 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591023513 ATP binding site [chemical binding]; other site 216591023514 Mg2+ binding site [ion binding]; other site 216591023515 G-X-G motif; other site 216591023516 2 probable transmembrane helices predicted for BCAM1195 by TMHMM2.0 at aa 5-27 and 184-206 216591023517 HMMPfam hit to PF00672, HAMP domain, score 3.2e-14 216591023518 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.6e-12 216591023519 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591023520 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 216591023521 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591023522 putative CheW interface [polypeptide binding]; other site 216591023523 1 probable transmembrane helix predicted for BCAM1196 by TMHMM2.0 at aa 5-27 216591023524 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 0.0012 216591023525 Chemotaxis phosphatase CheX; Region: CheX; pfam13690 216591023526 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 216591023527 FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784 216591023528 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591023529 active site 216591023530 phosphorylation site [posttranslational modification] 216591023531 intermolecular recognition site; other site 216591023532 dimerization interface [polypeptide binding]; other site 216591023533 HMMPfam hit to PF00072, Response regulator receiver domain, score 3.5e-25 216591023534 Protein of unknown function (DUF3592); Region: DUF3592; pfam12158 216591023535 2 probable transmembrane helices predicted for BCAM1200 by TMHMM2.0 at aa 27-49 and 121-143 216591023536 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591023537 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023538 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591023539 dimerization interface [polypeptide binding]; other site 216591023540 HMMPfam hit to PF03466, LysR substrate binding domain, score 7.4e-40 216591023541 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6e-17 216591023542 Predicted helix-turn-helix motif with score 1268.000, SD 3.51 at aa 16-37, sequence GTLRGAAAQLNVDQATVGRRIA 216591023543 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591023544 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591023545 putative substrate translocation pore; other site 216591023546 14 probable transmembrane helices predicted for BCAM1202 by TMHMM2.0 at aa 28-50, 65-87, 94-116, 120-142, 155-177, 182-204, 217-239, 244-263, 284-306, 316-338, 351-373, 378-400, 421-438 and 443-462 216591023547 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.4e-55 216591023548 enoyl-CoA hydratase; Validated; Region: PRK08139 216591023549 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591023550 substrate binding site [chemical binding]; other site 216591023551 oxyanion hole (OAH) forming residues; other site 216591023552 trimer interface [polypeptide binding]; other site 216591023553 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 2e-36 216591023554 alanine racemase; Reviewed; Region: PRK13340 216591023555 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827 216591023556 active site 216591023557 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 216591023558 substrate binding site [chemical binding]; other site 216591023559 catalytic residues [active] 216591023560 dimer interface [polypeptide binding]; other site 216591023561 HMMPfam hit to PF00842, Alanine racemase, C-terminal domain, score 1.4e-64 216591023562 HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 2.8e-72 216591023563 PS00395 Alanine racemase pyridoxal-phosphate attachment site. 216591023564 MAPEG family; Region: MAPEG; cl09190 216591023565 4 probable transmembrane helices predicted for BCAM1205 by TMHMM2.0 at aa 5-22, 54-71, 81-103 and 105-122 216591023566 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591023567 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023568 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591023569 dimerization interface [polypeptide binding]; other site 216591023570 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.8e-11 216591023571 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.3e-17 216591023572 PS00044 Bacterial regulatory proteins, lysR family signature. 216591023573 Predicted helix-turn-helix motif with score 1762.000, SD 5.19 at aa 20-41, sequence GGFARAAAELNVSTSAVSHQIR 216591023574 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 216591023575 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 216591023576 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591023577 Walker A/P-loop; other site 216591023578 ATP binding site [chemical binding]; other site 216591023579 Q-loop/lid; other site 216591023580 ABC transporter signature motif; other site 216591023581 Walker B; other site 216591023582 D-loop; other site 216591023583 H-loop/switch region; other site 216591023584 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124 216591023585 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591023586 Walker A/P-loop; other site 216591023587 ATP binding site [chemical binding]; other site 216591023588 Q-loop/lid; other site 216591023589 ABC transporter signature motif; other site 216591023590 Walker B; other site 216591023591 D-loop; other site 216591023592 H-loop/switch region; other site 216591023593 9 probable transmembrane helices predicted for BCAM1207 by TMHMM2.0 at aa 13-35, 50-72, 132-154, 158-177, 626-648, 658-680, 733-755, 759-781 and 853-875 216591023594 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 8.7e-06 216591023595 HMMPfam hit to PF00005, ABC transporter score 1.6e-61 216591023596 PS00017 ATP/GTP-binding site motif A (P-loop). 216591023597 PS00211 ABC transporters family signature. 216591023598 HMMPfam hit to PF00005, ABC transporter score 3.9e-65 216591023599 PS00017 ATP/GTP-binding site motif A (P-loop). 216591023600 PS00211 ABC transporters family signature. 216591023601 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591023602 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591023603 substrate binding pocket [chemical binding]; other site 216591023604 membrane-bound complex binding site; other site 216591023605 hinge residues; other site 216591023606 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.4e-86 216591023607 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591023608 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591023609 dimer interface [polypeptide binding]; other site 216591023610 conserved gate region; other site 216591023611 putative PBP binding loops; other site 216591023612 ABC-ATPase subunit interface; other site 216591023613 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 7.7e-26 216591023614 4 probable transmembrane helices predicted for BCAM1209 by TMHMM2.0 at aa 21-43, 67-84, 91-113 and 189-211 216591023615 glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493 216591023616 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 216591023617 Walker A/P-loop; other site 216591023618 ATP binding site [chemical binding]; other site 216591023619 Q-loop/lid; other site 216591023620 ABC transporter signature motif; other site 216591023621 Walker B; other site 216591023622 D-loop; other site 216591023623 H-loop/switch region; other site 216591023624 HMMPfam hit to PF00005, ABC transporter score 1.4e-65 216591023625 PS00017 ATP/GTP-binding site motif A (P-loop). 216591023626 PS00211 ABC transporters family signature. 216591023627 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; Region: AAT; pfam03417 216591023628 HMMPfam hit to PF03417, Acyl-coenzyme A:6-aminopenicillanic acid acy, score 3.8e-50 216591023629 hypothetical protein; Provisional; Region: PRK07483 216591023630 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591023631 inhibitor-cofactor binding pocket; inhibition site 216591023632 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591023633 catalytic residue [active] 216591023634 HMMPfam hit to PF00202, Aminotransferase class-III, score 2e-107 216591023635 PS00196 Type-1 copper (blue) proteins signature. 216591023636 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591023637 Carboxymuconolactone decarboxylase family; Region: CMD; cl00460 216591023638 1 probable transmembrane helix predicted for BCAM1213 by TMHMM2.0 at aa 150-172 216591023639 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555 216591023640 HMMPfam hit to PF05118, Aspartyl/Asparaginyl beta-hydroxylase, score 3.7e-80 216591023641 1 probable transmembrane helix predicted for BCAM1214 by TMHMM2.0 at aa 279-298 216591023642 1 probable transmembrane helix predicted for BCAM1215 by TMHMM2.0 at aa 7-29 216591023643 alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317 216591023644 Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974 216591023645 catalytic residue [active] 216591023646 TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026 216591023647 catalytic residues [active] 216591023648 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591023649 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591023650 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 1.6e-46 216591023651 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 6.2e-23 216591023652 PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 216591023653 peroxiredoxin; Region: AhpC; TIGR03137 216591023654 Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015 216591023655 dimer interface [polypeptide binding]; other site 216591023656 decamer (pentamer of dimers) interface [polypeptide binding]; other site 216591023657 catalytic triad [active] 216591023658 peroxidatic and resolving cysteines [active] 216591023659 HMMPfam hit to PF00578, AhpC/TSA family, score 5.9e-97 216591023660 HMMPfam hit to PF08534, Redoxin, score 2.7e-08 216591023661 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591023662 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023663 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591023664 dimerization interface [polypeptide binding]; other site 216591023665 substrate binding pocket [chemical binding]; other site 216591023666 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.4e-28 216591023667 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.5e-14 216591023668 PS00044 Bacterial regulatory proteins, lysR family signature. 216591023669 Predicted helix-turn-helix motif with score 1454.000, SD 4.14 at aa 26-47, sequence GSVTAAAGELDITPSAVSHQLQ 216591023670 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591023671 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 216591023672 dimerization interface [polypeptide binding]; other site 216591023673 ligand binding site [chemical binding]; other site 216591023674 HMMPfam hit to PF01094, Receptor family ligand binding region, score 1e-40 216591023675 L-2-amino-thiazoline-4-carboxylic acid hydrolase; Region: ATC_hydrolase; pfam14196 216591023676 allantoate amidohydrolase; Reviewed; Region: PRK12891 216591023677 M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884 216591023678 active site 216591023679 metal binding site [ion binding]; metal-binding site 216591023680 dimer interface [polypeptide binding]; other site 216591023681 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 8.3e-40 216591023682 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 2.4e-06 216591023683 PS00216 Sugar transport proteins signature 1. 216591023684 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591023685 Cytochrome c; Region: Cytochrom_C; pfam00034 216591023686 HMMPfam hit to PF00034, Cytochrome c, score 0.0013 216591023687 PS00190 Cytochrome c family heme-binding site signature. 216591023688 1 probable transmembrane helix predicted for BCAM1223 by TMHMM2.0 at aa 7-29 216591023689 glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331 216591023690 Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans). The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714 216591023691 glutaminase active site [active] 216591023692 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 216591023693 dimer interface [polypeptide binding]; other site 216591023694 active site 216591023695 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 216591023696 dimer interface [polypeptide binding]; other site 216591023697 active site 216591023698 HMMPfam hit to PF01380, SIS domain, score 4.7e-22 216591023699 HMMPfam hit to PF01380, SIS domain, score 2e-34 216591023700 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 1.5e-26 216591023701 PS00443 Glutamine amidotransferases class-II active site. 216591023702 2 probable transmembrane helices predicted for BCAM1225 by TMHMM2.0 at aa 20-42 and 52-74 216591023703 N-glycosyltransferase; Provisional; Region: PRK11204 216591023704 CESA_like is the cellulose synthase superfamily; Region: CESA_like; cd06423 216591023705 DXD motif; other site 216591023706 4 probable transmembrane helices predicted for BCAM1226 by TMHMM2.0 at aa 13-35, 300-322, 335-357 and 377-399 216591023707 HMMPfam hit to PF00535, Glycosyl transferase family, score 3.4e-27 216591023708 poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB; Region: deacetyl_PgaB; TIGR03938 216591023709 N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964 216591023710 putative active site [active] 216591023711 putative metal binding site [ion binding]; other site 216591023712 HMMPfam hit to PF01522, Polysaccharide deacetylase, score 5.5e-24 216591023713 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023714 poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA; Region: PGA_TPR_OMP; TIGR03939 216591023715 1 probable transmembrane helix predicted for BCAM1229 by TMHMM2.0 at aa 25-42 216591023716 cell density-dependent motility repressor; Provisional; Region: PRK10082 216591023717 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023718 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591023719 dimerization interface [polypeptide binding]; other site 216591023720 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.5e-20 216591023721 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.6e-15 216591023722 PS00044 Bacterial regulatory proteins, lysR family signature. 216591023723 Predicted helix-turn-helix motif with score 1288.000, SD 3.57 at aa 16-37, sequence KSFSRAARHRHLTQSAFSRRIA 216591023724 Uncharacterized conserved protein [Function unknown]; Region: COG2308 216591023725 HMMPfam hit to PF04169, Domain of unknown function (DUF404), score 1.9e-176 216591023726 HMMPfam hit to PF04174, Domain of unknown function (DUF407), score 3.3e-88 216591023727 A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168 216591023728 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307 216591023729 HMMPfam hit to PF04168, Bacterial domain of unknown function (DUF403, score 4.8e-136 216591023730 Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305 216591023731 Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379 216591023732 Transglutaminase-like superfamily; Region: Transglut_core; cl17362 216591023733 HMMPfam hit to PF08379, Bacterial transglutaminase-like N-ter, score 7.3e-27 216591023734 Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379 216591023735 Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305 216591023736 Transglutaminase-like superfamily; Region: Transglut_core; pfam01841 216591023737 Putative amidoligase enzyme (DUF2126); Region: DUF2126; pfam09899 216591023738 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4196 216591023739 HMMPfam hit to PF08379, Bacterial transglutaminase-like N-ter, score 1.2e-32 216591023740 HMMPfam hit to PF01841, Transglutaminase-like superfamily, score 1.7e-22 216591023741 A circularly permuted ATPgrasp; Region: CP_ATPgrasp_1; pfam04174 216591023742 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307 216591023743 A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168 216591023744 HMMPfam hit to PF04169, Domain of unknown function (DUF404), score 2.4e-103 216591023745 HMMPfam hit to PF04174, Domain of unknown function (DUF407), score 1.2e-19 216591023746 HMMPfam hit to PF04168, Bacterial domain of unknown function (DUF403, score 8.6e-09 216591023747 Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379 216591023748 Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305 216591023749 Transglutaminase-like superfamily; Region: Transglut_core; pfam01841 216591023750 HMMPfam hit to PF08379, Bacterial transglutaminase-like N-ter, score 1e-32 216591023751 HMMPfam hit to PF01841, Transglutaminase-like superfamily, score 3.4e-23 216591023752 proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249 216591023753 homoserine O-acetyltransferase; Provisional; Region: metX; cl17114 216591023754 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 3.9e-27 216591023755 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 216591023756 HMMPfam hit to PF01757, Acyltransferase family, score 3e-27 216591023757 10 probable transmembrane helices predicted for BCAM1241 by TMHMM2.0 at aa 13-35, 45-64, 85-107, 146-168, 175-197, 202-221, 234-253, 263-285, 298-315 and 325-344 216591023758 Protein of unknown function (DUF1311); Region: DUF1311; cl01530 216591023759 HMMPfam hit to PF07007, Protein of unknown function (DUF1311), score 3.5e-06 216591023760 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 216591023761 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591023762 catalytic residue [active] 216591023763 HMMPfam hit to PF00266, Aminotransferase class-V, score 2.3e-10 216591023764 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0012 216591023765 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 216591023766 phosphonopyruvate decarboxylase; Region: Ppyr-DeCO2ase; TIGR03297 216591023767 PYR/PP interface [polypeptide binding]; other site 216591023768 dimer interface [polypeptide binding]; other site 216591023769 TPP binding site [chemical binding]; other site 216591023770 Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of proteins similar to phosphonopyruvate decarboxylase (PpyrDC) proteins. PpyrDC is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as...; Region: TPP_PpyrDC; cd03371 216591023771 TPP-binding site; other site 216591023772 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 6.8e-11 216591023773 PS00187 Thiamine pyrophosphate enzymes signature. 216591023774 Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714 216591023775 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 216591023776 tetramer interface [polypeptide binding]; other site 216591023777 active site 216591023778 Mg2+/Mn2+ binding site [ion binding]; other site 216591023779 Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523 216591023780 active site 216591023781 metal-binding site 216591023782 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591023783 Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523 216591023784 active site 216591023785 metal-binding site 216591023786 Uncharacterized protein family (UPF0104); Region: UPF0104; cl04219 216591023787 5 probable transmembrane helices predicted for BCAM1247 by TMHMM2.0 at aa 5-27, 37-59, 115-137, 152-171 and 221-243 216591023788 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640 216591023789 HMMPfam hit to PF03171, 2OG-Fe(II) oxygenase superfamily, score 0.0041 216591023790 CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066 216591023791 HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 0.00091 216591023792 4 probable transmembrane helices predicted for BCAM1249 by TMHMM2.0 at aa 49-71, 99-118, 125-147 and 188-210 216591023793 PS00379 CDP-alcohol phosphatidyltransferases signature. 216591023794 Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550 216591023795 succinate CoA transferase; Region: YgfH_subfam; TIGR03458 216591023796 Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336 216591023797 HMMPfam hit to PF02550, Acetyl-CoA hydrolase/transferase, score 7.3e-145 216591023798 Interrupted by IS element after codon 62 216591023799 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.9e-59 216591023800 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591023801 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591023802 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591023803 HMMPfam hit to PF01548, Transposase, score 2.9e-12 216591023804 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591023805 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591023806 MarR family; Region: MarR_2; pfam12802 216591023807 HMMPfam hit to PF01047, MarR family, score 5.3e-15 216591023808 Predicted helix-turn-helix motif with score 1368.000, SD 3.85 at aa 50-71, sequence MNQARLAEWLEITPISLTRLLD 216591023809 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 216591023810 Sel1-like repeats; Region: SEL1; smart00671 216591023811 Sel1-like repeats; Region: SEL1; smart00671 216591023812 Sel1-like repeats; Region: SEL1; smart00671 216591023813 Sel1-like repeats; Region: SEL1; smart00671 216591023814 Sel1-like repeats; Region: SEL1; smart00671 216591023815 1 probable transmembrane helix predicted for BCAM1255 by TMHMM2.0 at aa 12-34 216591023816 HMMPfam hit to PF08238, Sel1 repeat, score 3.1e-11 216591023817 HMMPfam hit to PF08238, Sel1 repeat, score 1.1e-10 216591023818 HMMPfam hit to PF08238, Sel1 repeat, score 2.9e-09 216591023819 HMMPfam hit to PF08238, Sel1 repeat, score 7.6e-12 216591023820 HMMPfam hit to PF08238, Sel1 repeat, score 7.5e-11 216591023821 HMMPfam hit to PF08238, Sel1 repeat, score 1.3e-12 216591023822 HMMPfam hit to PF08238, Sel1 repeat, score 0.24 216591023823 Protein of unknown function (DUF2938); Region: DUF2938; pfam11158 216591023824 4 probable transmembrane helices predicted for BCAM1256 by TMHMM2.0 at aa 10-27, 70-92, 107-129 and 142-164 216591023825 Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044 216591023826 Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg6; cd04781 216591023827 DNA binding residues [nucleotide binding] 216591023828 putative dimer interface [polypeptide binding]; other site 216591023829 putative metal binding residues [ion binding]; other site 216591023830 Predicted helix-turn-helix motif with score 1567.000, SD 4.52 at aa 8-29, sequence LDIADVARRTGLPASTLRYYEE 216591023831 HMMPfam hit to PF00376, MerR family regulatory protein, score 2.1e-11 216591023832 RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966 216591023833 Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979 216591023834 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 216591023835 RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393 216591023836 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591023837 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 216591023838 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591023839 DNA binding residues [nucleotide binding] 216591023840 HMMPfam hit to PF04545, Sigma-70, region, score 2e-14 216591023841 Predicted helix-turn-helix motif with score 1485.000, SD 4.24 at aa 466-487, sequence DTYDAIAQDAGMSRERVRQIEK 216591023842 HMMPfam hit to PF04539, Sigma-70 region, score 4.1e-20 216591023843 HMMPfam hit to PF04542, Sigma-70 region, score 2.3e-28 216591023844 PS00715 Sigma-70 factors family signature 1. 216591023845 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 216591023846 HMMPfam hit to PF00140, Sigma-70 factor, region, score 5.3e-08 216591023847 HMMPfam hit to PF03979, Sigma-70 factor, region, score 5.5e-09 216591023848 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023849 Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown]; Region: COG4991 216591023850 Bacterial SH3 domain; Region: SH3_3; pfam08239 216591023851 2 probable transmembrane helices predicted for BCAM1261 by TMHMM2.0 at aa 5-23 and 94-116 216591023852 HMMPfam hit to PF06347, Bacterial SH3 domain, score 0.0038 216591023853 HMMPfam hit to PF08239, Bacterial SH3 domain, score 3.7e-05 216591023854 dihydroxy-acid dehydratase; Provisional; Region: PRK12448 216591023855 HMMPfam hit to PF00920, Dehydratase family, score 0 216591023856 PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 216591023857 PS00017 ATP/GTP-binding site motif A (P-loop). 216591023858 PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 216591023859 Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055 216591023860 HMMPfam hit to PF02615, Malate/L-lactate dehydrogenase, score 1.9e-53 216591023861 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591023862 NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012 216591023863 Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129 216591023864 dimer interface [polypeptide binding]; other site 216591023865 NADP binding site [chemical binding]; other site 216591023866 catalytic residues [active] 216591023867 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 7e-15 216591023868 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 216591023869 Spore germination protein; Region: Spore_permease; cl17796 216591023870 14 probable transmembrane helices predicted for BCAM1265 by TMHMM2.0 at aa 30-52, 62-84, 105-127, 149-171, 178-200, 220-242, 255-277, 300-322, 356-378, 383-405, 418-440, 444-466, 478-500 and 510-529 216591023871 HMMPfam hit to PF00324, Amino acid permease, score 5e-07 216591023872 Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329 216591023873 Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408 216591023874 inhibitor site; inhibition site 216591023875 active site 216591023876 dimer interface [polypeptide binding]; other site 216591023877 catalytic residue [active] 216591023878 HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 1.9e-50 216591023879 hydroxyproline-2-epimerase; Provisional; Region: PRK13970 216591023880 hydroxyproline-2-epimerase; Provisional; Region: PRK13971 216591023881 HMMPfam hit to PF05544, Proline racemase, score 1.3e-141 216591023882 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591023883 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591023884 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.9e-79 216591023885 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023886 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510 216591023887 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 0.012 216591023888 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992 216591023889 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 1.1e-23 216591023890 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591023891 pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424 216591023892 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591023893 dimerization interface [polypeptide binding]; other site 216591023894 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.8e-36 216591023895 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1e-18 216591023896 PS00044 Bacterial regulatory proteins, lysR family signature. 216591023897 Predicted helix-turn-helix motif with score 1380.000, SD 3.89 at aa 22-43, sequence GNLSQSAVALATTQPALSKWLK 216591023898 gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272 216591023899 Cupin domain; Region: Cupin_2; pfam07883 216591023900 HMMPfam hit to PF07883, Cupin domain, score 1.3e-20 216591023901 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 216591023902 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 216591023903 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 4.9e-61 216591023904 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 1.6e-12 216591023905 GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042 216591023906 maleylacetoacetate isomerase; Region: maiA; TIGR01262 216591023907 C-terminal domain interface [polypeptide binding]; other site 216591023908 GSH binding site (G-site) [chemical binding]; other site 216591023909 putative dimer interface [polypeptide binding]; other site 216591023910 C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191 216591023911 dimer interface [polypeptide binding]; other site 216591023912 maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site 216591023913 N-terminal domain interface [polypeptide binding]; other site 216591023914 salicylate hydroxylase; Provisional; Region: PRK08163 216591023915 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591023916 HMMPfam hit to PF01494, FAD binding domain, score 2.5e-08 216591023917 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 4.5e-06 216591023918 1 probable transmembrane helix predicted for BCAM1274 by TMHMM2.0 at aa 11-28 216591023919 benzoate transport; Region: 2A0115; TIGR00895 216591023920 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591023921 putative substrate translocation pore; other site 216591023922 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591023923 12 probable transmembrane helices predicted for BCAM1275 by TMHMM2.0 at aa 24-46, 61-83, 90-112, 116-138, 150-172, 177-199, 260-282, 292-314, 326-348, 352-374, 387-409 and 413-435 216591023924 HMMPfam hit to PF00083, Sugar (and other) transporter score 2.8e-06 216591023925 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.5e-48 216591023926 PS00217 Sugar transport proteins signature 2. 216591023927 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591023928 dimerization interface [polypeptide binding]; other site 216591023929 putative DNA binding site [nucleotide binding]; other site 216591023930 putative Zn2+ binding site [ion binding]; other site 216591023931 HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family, score 1.8e-12 216591023932 Predicted helix-turn-helix motif with score 1064.000, SD 2.81 at aa 46-67, sequence CCVSDLEARLDIHQPTLSQQLG 216591023933 Predicted transporter component [General function prediction only]; Region: COG2391 216591023934 4 probable transmembrane helices predicted for BCAM1277 by TMHMM2.0 at aa 10-32, 53-72, 82-104 and 117-139 216591023935 HMMPfam hit to PF04143, YeeE/YedE family (DUF395), score 2.4e-21 216591023936 4 probable transmembrane helices predicted for BCAM1278 by TMHMM2.0 at aa 5-23, 38-60, 84-106 and 116-133 216591023937 HMMPfam hit to PF04143, YeeE/YedE family (DUF395), score 3.4e-12 216591023938 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591023939 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591023940 DNA-binding site [nucleotide binding]; DNA binding site 216591023941 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591023942 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591023943 homodimer interface [polypeptide binding]; other site 216591023944 catalytic residue [active] 216591023945 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 8.9e-13 216591023946 PS00041 Bacterial regulatory proteins, araC family signature. 216591023947 HMMPfam hit to PF00155, Aminotransferase class I and II, score 8.6e-08 216591023948 Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858 216591023949 PS00190 Cytochrome c family heme-binding site signature. 216591023950 HMMPfam hit to PF03150, Di-haem cytochrome c peroxidase, score 1.7e-11 216591023951 PS00190 Cytochrome c family heme-binding site signature. 216591023952 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 216591023953 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 216591023954 active site 216591023955 metal binding site [ion binding]; metal-binding site 216591023956 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1e-13 216591023957 PS00125 Serine/threonine specific protein phosphatases signature. 216591023958 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591023959 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591023960 S-adenosylmethionine binding site [chemical binding]; other site 216591023961 HMMPfam hit to PF05175, Methyltransferase small domain, score 0.00049 216591023962 HMMPfam hit to PF08241, Methyltransferase domain, score 2.2e-26 216591023963 HMMPfam hit to PF08242, Methyltransferase domain, score 1.6e-14 216591023964 3 probable transmembrane helices predicted for BCAM1285 by TMHMM2.0 at aa 10-32, 39-61 and 76-98 216591023965 BCCT family transporter; Region: BCCT; pfam02028 216591023966 HMMPfam hit to PF02028, BCCT family transporter score 1.2e-229 216591023967 12 probable transmembrane helices predicted for BCAM1286 by TMHMM2.0 at aa 16-38, 48-70, 91-113, 147-169, 189-211, 231-253, 265-287, 317-339, 352-371, 412-434, 451-473 and 478-500 216591023968 PS01303 BCCT family of transporters signature. 216591023969 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591023970 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591023971 trimer interface [polypeptide binding]; other site 216591023972 eyelet of channel; other site 216591023973 HMMPfam hit to PF00267, Gram-negative porin, score 3e-05 216591023974 Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501 216591023975 Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802 216591023976 Glycosyl hydrolase family 31 (GH31) domain of a bacterial protein family represented by Escherichia coli protein Aec37. The gene encoding Aec37 (aec-37) is located within a genomic island (AGI-3) isolated from the extraintestinal avian pathogenic...; Region: GH31_glycosidase_Aec37; cd06599 216591023977 putative active site [active] 216591023978 putative catalytic site [active] 216591023979 HMMPfam hit to PF01055, Glycosyl hydrolases family, score 5.5e-167 216591023980 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591023981 D-galactonate transporter; Region: 2A0114; TIGR00893 216591023982 putative substrate translocation pore; other site 216591023983 12 probable transmembrane helices predicted for BCAM1289 by TMHMM2.0 at aa 7-24, 47-69, 76-98, 108-127, 134-156, 161-183, 225-247, 262-284, 297-319, 324-346, 359-381 and 386-408 216591023984 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.9e-67 216591023985 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 216591023986 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 216591023987 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 216591023988 putative active site [active] 216591023989 HMMPfam hit to PF01418, Helix-turn-helix domain, rpiR family, score 0.00036 216591023990 HMMPfam hit to PF01380, SIS domain, score 3.7e-11 216591023991 Ntn-hydrolase superfamily, L-Asparaginase type 2-like enzymes. This family includes Glycosylasparaginase, Taspase 1 and L-Asparaginase type 2 enzymes. Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked...; Region: Ntn_Asparaginase_2_like; cl00635 216591023992 L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701 216591023993 catalytic nucleophile [active] 216591023994 HMMPfam hit to PF01112, Asparaginase, score 5.6e-112 216591023995 glutathione transporter ATP-binding protein; Provisional; Region: PRK10261 216591023996 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591023997 Walker A/P-loop; other site 216591023998 ATP binding site [chemical binding]; other site 216591023999 Q-loop/lid; other site 216591024000 ABC transporter signature motif; other site 216591024001 Walker B; other site 216591024002 D-loop; other site 216591024003 H-loop/switch region; other site 216591024004 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 216591024005 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591024006 Walker A/P-loop; other site 216591024007 ATP binding site [chemical binding]; other site 216591024008 Q-loop/lid; other site 216591024009 ABC transporter signature motif; other site 216591024010 Walker B; other site 216591024011 D-loop; other site 216591024012 H-loop/switch region; other site 216591024013 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352 216591024014 HMMPfam hit to PF00005, ABC transporter score 4.1e-56 216591024015 PS00017 ATP/GTP-binding site motif A (P-loop). 216591024016 PS00211 ABC transporters family signature. 216591024017 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter C-termi, score 5.2e-05 216591024018 HMMPfam hit to PF00005, ABC transporter score 5.4e-63 216591024019 PS00017 ATP/GTP-binding site motif A (P-loop). 216591024020 PS00211 ABC transporters family signature. 216591024021 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter C-termi, score 7.3e-08 216591024022 glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413 216591024023 The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499 216591024024 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 5.2e-89 216591024025 glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081 216591024026 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591024027 dimer interface [polypeptide binding]; other site 216591024028 conserved gate region; other site 216591024029 putative PBP binding loops; other site 216591024030 ABC-ATPase subunit interface; other site 216591024031 6 probable transmembrane helices predicted for BCAM1294 by TMHMM2.0 at aa 9-31, 101-123, 135-157, 172-191, 227-249 and 277-299 216591024032 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.7e-48 216591024033 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591024034 glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082 216591024035 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591024036 dimer interface [polypeptide binding]; other site 216591024037 conserved gate region; other site 216591024038 putative PBP binding loops; other site 216591024039 ABC-ATPase subunit interface; other site 216591024040 6 probable transmembrane helices predicted for BCAM1295 by TMHMM2.0 at aa 32-54, 96-118, 131-153, 157-176, 214-236 and 261-283 216591024041 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.2e-52 216591024042 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591024043 L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active...; Region: DmpA; cd02253 216591024044 homodimer interface [polypeptide binding]; other site 216591024045 homotetramer interface [polypeptide binding]; other site 216591024046 active site pocket [active] 216591024047 cleavage site 216591024048 HMMPfam hit to PF03576, Peptidase family T4, score 1.1e-85 216591024049 Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA_1; cd08663 216591024050 SxDxEG motif; other site 216591024051 active site 216591024052 metal binding site [ion binding]; metal-binding site 216591024053 homopentamer interface [polypeptide binding]; other site 216591024054 HMMPfam hit to PF04951, D-aminopeptidase, score 4.3e-53 216591024055 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591024056 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 5.7e-07 216591024057 PS00041 Bacterial regulatory proteins, araC family signature. 216591024058 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00013 216591024059 Protocatechuate 3,4-dioxygenase (3,4-PCD) , alpha subunit. 3,4-PCD catalyzes the oxidative ring cleavage of 3,4-dihydroxybenzoate to produce beta-carboxy-cis,cis-muconate. 3,4-PCDs are large aggregates of 12 protomers, each composed of an alpha- and...; Region: 3,4-PCD_alpha; cd03463 216591024060 heterodimer interface [polypeptide binding]; other site 216591024061 active site 216591024062 HMMPfam hit to PF00775, Dioxygenase, score 0.00053 216591024063 Protocatechuate 3,4-dioxygenase (3,4-PCD) , beta subunit. 3,4-PCD catalyzes the oxidative ring cleavage of 3,4-dihydroxybenzoate to produce beta-carboxy-cis,cis-muconate. 3,4-PCDs are large aggregates of 12 protomers, each composed of an alpha- and...; Region: 3,4-PCD_beta; cd03464 216591024064 heterodimer interface [polypeptide binding]; other site 216591024065 multimer interface [polypeptide binding]; other site 216591024066 protocatechuate 3,4-dioxygenase, beta subunit; Region: protocat_beta; TIGR02422 216591024067 active site 216591024068 HMMPfam hit to PF00775, Dioxygenase, score 4.1e-89 216591024069 PS00083 Intradiol ring-cleavage dioxygenases signature. 216591024070 Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998 216591024071 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591024072 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591024073 non-specific DNA binding site [nucleotide binding]; other site 216591024074 salt bridge; other site 216591024075 sequence-specific DNA binding site [nucleotide binding]; other site 216591024076 HMMPfam hit to PF01381, Helix-turn-helix, score 1.7e-09 216591024077 Predicted helix-turn-helix motif with score 1970.000, SD 5.90 at aa 20-41, sequence MTYRDVARALDVSETSVKRLFA 216591024078 PS00215 Mitochondrial energy transfer proteins signature. 216591024079 pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424 216591024080 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591024081 The C-terminal substrate binding domain of galactose-binding protein regulator contains the type 2 periplasmic binding fold; Region: PBP2_GbpR; cd08435 216591024082 putative dimerization interface [polypeptide binding]; other site 216591024083 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.1e-21 216591024084 Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 25-46, sequence GGVQKAAESLSITQPAVSKTIA 216591024085 PS00044 Bacterial regulatory proteins, lysR family signature. 216591024086 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.8e-39 216591024087 Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973 216591024088 HMMPfam hit to PF05973, Phage derived protein Gp49-like (DUF891), score 0.00017 216591024089 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 216591024090 Predicted helix-turn-helix motif with score 1244.000, SD 3.42 at aa 54-75, sequence ITKTAMAARMKTSRAALNRLLD 216591024091 putative transporter; Provisional; Region: PRK11021 216591024092 putative transporter; Provisional; Region: PRK11021 216591024093 11 probable transmembrane helices predicted for BCAM1306 by TMHMM2.0 at aa 13-35, 50-72, 93-115, 130-152, 157-176, 186-208, 229-251, 266-288, 327-344, 354-376 and 389-411 216591024094 HMMPfam hit to PF00324, Amino acid permease, score 2.5e-06 216591024095 HMMPfam hit to PF03845, Spore germination protein, score 0.0011 216591024096 Lhr-like helicases [General function prediction only]; Region: Lhr; COG1201 216591024097 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 216591024098 ATP binding site [chemical binding]; other site 216591024099 putative Mg++ binding site [ion binding]; other site 216591024100 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591024101 nucleotide binding region [chemical binding]; other site 216591024102 ATP-binding site [chemical binding]; other site 216591024103 DEAD/H associated; Region: DEAD_assoc; pfam08494 216591024104 HMMPfam hit to PF08494, DEAD/H associated, score 5.3e-79 216591024105 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 8e-15 216591024106 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 2e-34 216591024107 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591024108 PS00017 ATP/GTP-binding site motif A (P-loop). 216591024109 Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307 216591024110 5 probable transmembrane helices predicted for BCAM1308 by TMHMM2.0 at aa 9-31, 35-57, 70-89, 93-112 and 132-154 216591024111 Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405 216591024112 Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019 216591024113 HMMPfam hit to PF01019, Gamma-glutamyltranspeptidase, score 1.7e-230 216591024114 PS00462 Gamma-glutamyltranspeptidase signature. 216591024115 Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707 216591024116 ANTAR domain; Region: ANTAR; pfam03861 216591024117 HMMPfam hit to PF03861, ANTAR domain, score 2.4e-10 216591024118 Periplasmic binding protein; Region: Peripla_BP_6; pfam13458 216591024119 Periplasmic binding domain of amidase (AmiC) that belongs to the type I periplasmic binding fold protein family; Region: PBP1_AmiC; cd06357 216591024120 ligand binding site [chemical binding]; other site 216591024121 regulator interaction site; other site 216591024122 Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057 216591024123 metal ion-dependent adhesion site (MIDAS); other site 216591024124 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591024125 MoxR-like ATPases [General function prediction only]; Region: COG0714 216591024126 Walker A motif; other site 216591024127 ATP binding site [chemical binding]; other site 216591024128 Walker B motif; other site 216591024129 CbbQ/NirQ/NorQ C-terminal; Region: CbbQ_C; pfam08406 216591024130 HMMPfam hit to PF08406, CbbQ/NirQ/NorQ C-terminal, score 2.5e-38 216591024131 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 7e-42 216591024132 PS00017 ATP/GTP-binding site motif A (P-loop). 216591024133 AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293 216591024134 HMMPfam hit to PF02293, AmiS/UreI family transporter score 4.9e-43 216591024135 6 probable transmembrane helices predicted for BCAM1314 by TMHMM2.0 at aa 4-22, 29-51, 56-78, 85-104, 109-128 and 135-157 216591024136 acylamide amidohydrolase; Provisional; Region: amiE; PRK13286 216591024137 aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565 216591024138 multimer interface [polypeptide binding]; other site 216591024139 active site 216591024140 catalytic triad [active] 216591024141 dimer interface [polypeptide binding]; other site 216591024142 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 3.1e-42 216591024143 type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844 216591024144 HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.9e-19 216591024145 HMMPfam hit to PF02321, Outer membrane efflux protein, score 2e-18 216591024146 PS00228 Tubulin-beta mRNA autoregulation signal. 216591024147 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274 216591024148 A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419 216591024149 putative active site [active] 216591024150 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 216591024151 ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228 216591024152 Walker A/P-loop; other site 216591024153 ATP binding site [chemical binding]; other site 216591024154 Q-loop/lid; other site 216591024155 ABC transporter signature motif; other site 216591024156 Walker B; other site 216591024157 D-loop; other site 216591024158 H-loop/switch region; other site 216591024159 HMMPfam hit to PF03412, Peptidase C39 family, score 9.1e-30 216591024160 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 2.5e-21 216591024161 3 probable transmembrane helices predicted for BCAM1317 by TMHMM2.0 at aa 163-185, 200-222 and 293-315 216591024162 HMMPfam hit to PF00005, ABC transporter score 8.6e-45 216591024163 PS00017 ATP/GTP-binding site motif A (P-loop). 216591024164 PS00211 ABC transporters family signature. 216591024165 Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185 216591024166 putative acyl-acceptor binding pocket; other site 216591024167 type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843 216591024168 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591024169 1 probable transmembrane helix predicted for BCAM1319 by TMHMM2.0 at aa 39-61 216591024170 PS00543 HlyD family secretion proteins signature. 216591024171 OmpW family; Region: OmpW; cl17427 216591024172 HMMPfam hit to PF03922, OmpW family, score 2.4e-06 216591024173 polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707 216591024174 HMMPfam hit to PF03976, Polyphosphate kinase, score 7.1e-170 216591024175 Uncharacterized conserved protein [Function unknown]; Region: COG1739 216591024176 Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205 216591024177 Domain of unknown function (DUF1949); Region: DUF1949; pfam09186 216591024178 HMMPfam hit to PF01205, Uncharacterized protein family UPF0029, score 1.3e-44 216591024179 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591024180 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591024181 dimerization interface [polypeptide binding]; other site 216591024182 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.2e-17 216591024183 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 7e-17 216591024184 PS00044 Bacterial regulatory proteins, lysR family signature. 216591024185 Predicted helix-turn-helix motif with score 1385.000, SD 3.90 at aa 20-41, sequence KSFTRAAEVLDTTQSAVSLKIK 216591024186 1 probable transmembrane helix predicted for BCAM1325A by TMHMM2.0 at aa 15-37 216591024187 Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933 216591024188 Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472 216591024189 Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915 216591024190 Fibronectin type III-like domain; Region: Fn3-like; pfam14310 216591024191 HMMPfam hit to PF01915, Glycosyl hydrolase family 3 C termina, score 1.4e-75 216591024192 HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N termina, score 8.2e-86 216591024193 Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708 216591024194 This CDS appears to have two frameshift mutations 216591024195 Periplasmic protein involved in polysaccharide export, contains SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596 216591024196 Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563 216591024197 SLBB domain; Region: SLBB; pfam10531 216591024198 HMMPfam hit to PF02563, Polysaccharide biosynthesis/export protei, score 2.2e-31 216591024199 1 probable transmembrane helix predicted for BCAM1330 by TMHMM2.0 at aa 24-46 216591024200 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591024201 Chain length determinant protein; Region: Wzz; cl15801 216591024202 tyrosine kinase; Provisional; Region: PRK11519 216591024203 G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807 216591024204 Chain length determinant protein; Region: Wzz; cl15801 216591024205 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 216591024206 HMMPfam hit to PF02706, Chain length determinant protein, score 3.3e-20 216591024207 2 probable transmembrane helices predicted for BCAM1331 by TMHMM2.0 at aa 43-65 and 453-475 216591024208 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591024209 12 probable transmembrane helices predicted for BCAM1332 by TMHMM2.0 at aa 48-70, 74-96, 101-123, 138-160, 181-203, 226-248, 255-272, 276-293, 300-322, 422-444, 457-474 and 479-501 216591024210 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 216591024211 HMMPfam hit to PF01757, Acyltransferase family, score 1.1e-07 216591024212 10 probable transmembrane helices predicted for BCAM1333 by TMHMM2.0 at aa 13-30, 50-72, 88-110, 135-157, 164-183, 198-215, 236-258, 273-290, 297-319 and 329-351 216591024213 exosortase A system-associated hydrolase 1; Region: hydr1_PEP; TIGR03100 216591024214 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 216591024215 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591024216 HMMPfam hit to PF00534, Glycosyl transferases group, score 7.5e-07 216591024217 Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244 216591024218 Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128 216591024219 HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 9.8e-45 216591024220 10 probable transmembrane helices predicted for BCAM1336 by TMHMM2.0 at aa 7-29, 39-57, 77-99, 114-133, 140-162, 167-189, 288-307, 322-344, 356-378 and 382-404 216591024221 This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809 216591024222 Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439 216591024223 HMMPfam hit to PF00534, Glycosyl transferases group, score 1.2e-32 216591024224 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591024225 This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808 216591024226 putative ADP-binding pocket [chemical binding]; other site 216591024227 HMMPfam hit to PF00534, Glycosyl transferases group, score 1.4e-28 216591024228 Disaggregatase related; Region: Disaggr_assoc; pfam08480 216591024229 Right handed beta helix region; Region: Beta_helix; pfam13229 216591024230 1 probable transmembrane helix predicted for BCAM1339 by TMHMM2.0 at aa 13-35 216591024231 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479 216591024232 GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509 216591024233 Substrate binding site; other site 216591024234 Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050 216591024235 HMMPfam hit to PF01050, Mannose-6-phosphate isomerase, score 4.7e-119 216591024236 HMMPfam hit to PF07883, Cupin domain, score 2e-07 216591024237 HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.3e-76 216591024238 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 216591024239 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 216591024240 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591024241 Walker A motif; other site 216591024242 ATP binding site [chemical binding]; other site 216591024243 Walker B motif; other site 216591024244 arginine finger; other site 216591024245 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591024246 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 6.3e-131 216591024247 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591024248 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591024249 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 2.9e-10 216591024250 Predicted helix-turn-helix motif with score 1778.000, SD 5.24 at aa 428-449, sequence GRVAASARELGVSRATLYRWME 216591024251 Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250 216591024252 HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunoglo, score 0.065 216591024253 Domain of unknown function (DUF1839); Region: DUF1839; pfam08893 216591024254 Gly_His_Pro_Ser_Thr_tRNA synthetase class II core domain. This domain is the core catalytic domain of tRNA synthetases of the subgroup containing glycyl, histidyl, prolyl, seryl and threonyl tRNA synthetases. It is primarily responsible for ATP-dependent...; Region: Gly_His_Pro_Ser_Thr_tRS_core; cd00670 216591024255 dimer interface [polypeptide binding]; other site 216591024256 motif 1; other site 216591024257 active site 216591024258 motif 2; other site 216591024259 motif 3; other site 216591024260 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591024261 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591024262 Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771 216591024263 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591024264 active site 216591024265 acyl carrier protein; Provisional; Region: PRK07081 216591024266 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.3e-09 216591024267 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 216591024268 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 216591024269 ligand binding site [chemical binding]; other site 216591024270 flexible hinge region; other site 216591024271 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 216591024272 Predicted helix-turn-helix motif with score 978.000, SD 2.52 at aa 185-206, sequence VTHSMLAQMLGVRRETVTDAAG 216591024273 HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 2.4e-08 216591024274 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 216591024275 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 216591024276 non-specific DNA interactions [nucleotide binding]; other site 216591024277 DNA binding site [nucleotide binding] 216591024278 sequence specific DNA binding site [nucleotide binding]; other site 216591024279 putative cAMP binding site [chemical binding]; other site 216591024280 Undecaprenyl-phosphate glucose phosphotransferase; Region: WcaJ_sugtrans; TIGR03023 216591024281 Bacterial sugar transferase; Region: Bac_transf; pfam02397 216591024282 5 probable transmembrane helices predicted for BCAM1350 by TMHMM2.0 at aa 7-29, 39-58, 71-93, 108-127 and 277-296 216591024283 HMMPfam hit to PF02397, Bacterial sugar transferase, score 3.5e-34 216591024284 DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734 216591024285 HMMPfam hit to PF01258, Prokaryotic dksA/traR C4-type zinc finge, score 3.3e-07 216591024286 Nucleotidyltransferase (NT) domain of family X DNA Polymerases; Region: NT_POLXc; cd00141 216591024287 hypothetical protein; Provisional; Region: PRK08609 216591024288 active site 216591024289 primer binding site [nucleotide binding]; other site 216591024290 NTP binding site [chemical binding]; other site 216591024291 metal binding triad [ion binding]; metal-binding site 216591024292 Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436 216591024293 active site 216591024294 HMMPfam hit to PF02811, PHP domain, score 1.3e-21 216591024295 Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686 216591024296 Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305 216591024297 hexamer interface [polypeptide binding]; other site 216591024298 ligand binding site [chemical binding]; other site 216591024299 putative active site [active] 216591024300 NAD(P) binding site [chemical binding]; other site 216591024301 HMMPfam hit to PF01262, Alanine dehydrogenase/PNT, C-terminal dom, score 5.3e-83 216591024302 HMMPfam hit to PF05222, Alanine dehydrogenase/PNT, N-terminal dom, score 7.1e-70 216591024303 Protein of unknown function (DUF3995); Region: DUF3995; pfam13160 216591024304 4 probable transmembrane helices predicted for BCAM1354 by TMHMM2.0 at aa 5-27, 48-67, 77-99 and 120-139 216591024305 RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859 216591024306 Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618 216591024307 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591024308 Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303 216591024309 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 216591024310 HMMPfam hit to PF00732, GMC oxidoreductase, score 2.1e-05 216591024311 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591024312 Cytochrome c; Region: Cytochrom_C; pfam00034 216591024313 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591024314 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591024315 Cytochrome c; Region: Cytochrom_C; pfam00034 216591024316 1 probable transmembrane helix predicted for BCAM1358 by TMHMM2.0 at aa 20-42 216591024317 PS00190 Cytochrome c family heme-binding site signature. 216591024318 PS00190 Cytochrome c family heme-binding site signature. 216591024319 HMMPfam hit to PF00034, Cytochrome c, score 1.6e-08 216591024320 PS00190 Cytochrome c family heme-binding site signature. 216591024321 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482 216591024322 putative cation:proton antiport protein; Provisional; Region: PRK10669 216591024323 TrkA-N domain; Region: TrkA_N; pfam02254 216591024324 11 probable transmembrane helices predicted for BCAM1359 by TMHMM2.0 at aa 5-27, 34-56, 60-82, 87-109, 114-136, 149-171, 191-213, 234-256, 310-332, 339-361 and 376-398 216591024325 HMMPfam hit to PF00999, Sodium/hydrogen exchanger family, score 6.8e-80 216591024326 PS00017 ATP/GTP-binding site motif A (P-loop). 216591024327 HMMPfam hit to PF02254, TrkA-N domain, score 3.3e-25 216591024328 short chain dehydrogenase; Provisional; Region: PRK07074 216591024329 classical (c) SDRs; Region: SDR_c; cd05233 216591024330 NAD(P) binding site [chemical binding]; other site 216591024331 active site 216591024332 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0013 216591024333 HMMPfam hit to PF00106, short chain dehydrogenase, score 6.5e-16 216591024334 Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532 216591024335 Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540 216591024336 ligand binding site [chemical binding]; other site 216591024337 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 1.3e-45 216591024338 Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768 216591024339 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 216591024340 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 216591024341 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 3.3e-90 216591024342 PS00017 ATP/GTP-binding site motif A (P-loop). 216591024343 HMMPfam hit to PF03717, Penicillin-binding Protein dimerisatio, score 1e-40 216591024344 1 probable transmembrane helix predicted for BCAM1362 by TMHMM2.0 at aa 33-52 216591024345 Protein of unknown function (DUF3564); Region: DUF3564; pfam12087 216591024346 NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370 216591024347 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591024348 NAD(P) binding site [chemical binding]; other site 216591024349 active site 216591024350 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591024351 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 3.3e-05 216591024352 HMMPfam hit to PF07993, Male sterility protein, score 2.2e-13 216591024353 MarR family; Region: MarR_2; cl17246 216591024354 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591024355 HMMPfam hit to PF01047, MarR family, score 1.1e-15 216591024356 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 216591024357 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 6.5e-13 216591024358 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303 216591024359 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 216591024360 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 2e-73 216591024361 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299 216591024362 Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093 216591024363 NAD binding site [chemical binding]; other site 216591024364 catalytic residues [active] 216591024365 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.5e-236 216591024366 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591024367 PS00070 Aldehyde dehydrogenases cysteine active site. 216591024368 The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370 216591024369 Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900 216591024370 putative active site [active] 216591024371 putative metal binding site [ion binding]; other site 216591024372 HMMPfam hit to PF02900, Catalytic LigB subunit of aromatic ring-open, score 2.5e-74 216591024373 5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580 216591024374 putative substrate binding pocket [chemical binding]; other site 216591024375 trimer interface [polypeptide binding]; other site 216591024376 HMMPfam hit to PF02962, 5-carboxymethyl-2-hydroxymuconate isomerase, score 1.1e-59 216591024377 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 216591024378 HMMPfam hit to PF01689, Hydratase/decarboxylase, score 5.7e-134 216591024379 HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231 216591024380 HMMPfam hit to PF03328, HpcH/HpaI aldolase/citrate lyase family, score 7.3e-107 216591024381 Cupin domain; Region: Cupin_2; cl17218 216591024382 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591024383 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591024384 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.4e-06 216591024385 PS00041 Bacterial regulatory proteins, araC family signature. 216591024386 Predicted helix-turn-helix motif with score 1376.000, SD 3.87 at aa 174-195, sequence RRLEEWAEWAGIGARTMSRRFV 216591024387 NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604 216591024388 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 216591024389 NAD(P) binding site [chemical binding]; other site 216591024390 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 0.00043 216591024391 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.5e-12 216591024392 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591024393 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591024394 eyelet of channel; other site 216591024395 trimer interface [polypeptide binding]; other site 216591024396 HMMPfam hit to PF00267, Gram-negative porin, score 7.8e-06 216591024397 ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259 216591024398 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 216591024399 Walker A/P-loop; other site 216591024400 ATP binding site [chemical binding]; other site 216591024401 Q-loop/lid; other site 216591024402 ABC transporter signature motif; other site 216591024403 Walker B; other site 216591024404 D-loop; other site 216591024405 H-loop/switch region; other site 216591024406 HMMPfam hit to PF00005, ABC transporter score 5.4e-61 216591024407 PS00211 ABC transporters family signature. 216591024408 PS00017 ATP/GTP-binding site motif A (P-loop). 216591024409 ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178 216591024410 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591024411 dimer interface [polypeptide binding]; other site 216591024412 conserved gate region; other site 216591024413 ABC-ATPase subunit interface; other site 216591024414 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591024415 dimer interface [polypeptide binding]; other site 216591024416 conserved gate region; other site 216591024417 putative PBP binding loops; other site 216591024418 ABC-ATPase subunit interface; other site 216591024419 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.0021 216591024420 13 probable transmembrane helices predicted for BCAM1378 by TMHMM2.0 at aa 41-63, 96-118, 131-153, 173-195, 233-255, 278-300, 327-349, 392-414, 427-449, 459-476, 511-529, 534-556 and 563-585 216591024421 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591024422 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.4e-15 216591024423 PS00283 Soybean trypsin inhibitor (Kunitz) protease inhibitors family signature. 216591024424 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591024425 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 216591024426 Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416 216591024427 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 9e-11 216591024428 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591024429 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591024430 DNA-binding site [nucleotide binding]; DNA binding site 216591024431 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591024432 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591024433 homodimer interface [polypeptide binding]; other site 216591024434 catalytic residue [active] 216591024435 HMMPfam hit to PF00155, Aminotransferase class I and II, score 7.9e-07 216591024436 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 216591024437 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 1.2e-09 216591024438 drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710 216591024439 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591024440 putative substrate translocation pore; other site 216591024441 12 probable transmembrane helices predicted for BCAM1381 by TMHMM2.0 at aa 12-31, 46-68, 75-97, 101-123, 136-158, 163-185, 214-232, 247-269, 281-303, 308-330, 342-364 and 368-390 216591024442 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.4e-49 216591024443 PS00216 Sugar transport proteins signature 1. 216591024444 transcriptional regulatory protein TctD; Provisional; Region: PRK15479 216591024445 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591024446 active site 216591024447 phosphorylation site [posttranslational modification] 216591024448 intermolecular recognition site; other site 216591024449 dimerization interface [polypeptide binding]; other site 216591024450 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591024451 DNA binding site [nucleotide binding] 216591024452 HMMPfam hit to PF00072, Response regulator receiver domain, score 5.5e-37 216591024453 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 2.8e-19 216591024454 Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521 216591024455 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054 216591024456 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591024457 dimer interface [polypeptide binding]; other site 216591024458 phosphorylation site [posttranslational modification] 216591024459 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591024460 ATP binding site [chemical binding]; other site 216591024461 Mg2+ binding site [ion binding]; other site 216591024462 G-X-G motif; other site 216591024463 2 probable transmembrane helices predicted for BCAM1383 by TMHMM2.0 at aa 10-29 and 169-191 216591024464 HMMPfam hit to PF08521, Two-component sensor kinase N-terminal, score 3.5e-69 216591024465 HMMPfam hit to PF00672, HAMP domain, score 5.1e-09 216591024466 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1e-15 216591024467 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2.5e-37 216591024468 Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217 216591024469 MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476 216591024470 MOSC domain; Region: MOSC; pfam03473 216591024471 HMMPfam hit to PF03473, MOSC domain, score 1.5e-16 216591024472 HMMPfam hit to PF03476, MOSC N-terminal beta barrel domain, score 7.8e-49 216591024473 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432 216591024474 membrane-bound complex binding site; other site 216591024475 Cytochrome c; Region: Cytochrom_C; pfam00034 216591024476 HMMPfam hit to PF00034, Cytochrome c, score 0.014 216591024477 PS00190 Cytochrome c family heme-binding site signature. 216591024478 2 probable transmembrane helices predicted for BCAM1386 by TMHMM2.0 at aa 60-82 and 89-111 216591024479 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591024480 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 216591024481 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 216591024482 Walker A/P-loop; other site 216591024483 ATP binding site [chemical binding]; other site 216591024484 Q-loop/lid; other site 216591024485 ABC transporter signature motif; other site 216591024486 Walker B; other site 216591024487 D-loop; other site 216591024488 H-loop/switch region; other site 216591024489 HMMPfam hit to PF00005, ABC transporter score 6.8e-52 216591024490 PS00211 ABC transporters family signature. 216591024491 PS00017 ATP/GTP-binding site motif A (P-loop). 216591024492 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591024493 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591024494 dimer interface [polypeptide binding]; other site 216591024495 conserved gate region; other site 216591024496 putative PBP binding loops; other site 216591024497 ABC-ATPase subunit interface; other site 216591024498 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 7.6e-12 216591024499 8 probable transmembrane helices predicted for BCAM1388 by TMHMM2.0 at aa 47-69, 84-106, 118-137, 174-196, 209-226, 231-253, 273-295 and 329-351 216591024500 NMT1-like family; Region: NMT1_2; pfam13379 216591024501 NMT1/THI5 like; Region: NMT1; pfam09084 216591024502 hypothetical protein; Provisional; Region: PRK06208 216591024503 active site 216591024504 intersubunit interface [polypeptide binding]; other site 216591024505 Zn2+ binding site [ion binding]; other site 216591024506 HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 1e-58 216591024507 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 216591024508 Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094 216591024509 alkanesulfonate monooxygenase, FMNH(2)-dependent; Region: alk_sulf_monoox; TIGR03565 216591024510 dimer interface [polypeptide binding]; other site 216591024511 active site 216591024512 non-prolyl cis peptide bond; other site 216591024513 insertion regions; other site 216591024514 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 5e-08 216591024515 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591024516 Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771 216591024517 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 216591024518 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 8e-07 216591024519 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 0.0036 216591024520 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 5.4e-06 216591024521 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591024522 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591024523 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591024524 dimerization interface [polypeptide binding]; other site 216591024525 HMMPfam hit to PF03466, LysR substrate binding domain, score 6e-29 216591024526 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 7.3e-19 216591024527 PS00044 Bacterial regulatory proteins, lysR family signature. 216591024528 Predicted helix-turn-helix motif with score 1760.000, SD 5.18 at aa 16-37, sequence QTLSQAAAELGMTQPAITRRVQ 216591024529 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily [General function prediction only]; Region: COG5553 216591024530 HMMPfam hit to PF05995, Cysteine dioxygenase type I, score 6.2e-06 216591024531 Member of the Rhodanese Homology Domain superfamily, repeat 1. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 1st repeat which does not contain the putative...; Region: 4RHOD_Repeat_1; cd01532 216591024532 active site residue [active] 216591024533 Member of the Rhodanese Homology Domain superfamily, repeat 2. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 2nd repeat which does contain the putative catalytic...; Region: 4RHOD_Repeat_2; cd01533 216591024534 active site residue [active] 216591024535 Member of the Rhodanese Homology Domain superfamily, repeat 3. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 3rd repeat which does not contain the putative...; Region: 4RHOD_Repeat_3; cd01534 216591024536 active site residue [active] 216591024537 Member of the Rhodanese Homology Domain superfamily, repeat 4. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 4th repeat which, in general, contains the putative...; Region: 4RHOD_Repeat_4; cd01535 216591024538 active site residue [active] 216591024539 HMMPfam hit to PF00581, Rhodanese-like domain, score 2.1e-12 216591024540 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 216591024541 Glycerophosphodiester phosphodiesterase domain of Streptomycin coelicolor (GlpQ1) and similar proteins; Region: GDPD_ScGlpQ1_like; cd08602 216591024542 putative active site [active] 216591024543 catalytic site [active] 216591024544 putative metal binding site [ion binding]; other site 216591024545 HMMPfam hit to PF03009, Glycerophosphoryl diester phosphodiesterase, score 1.9e-50 216591024546 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591024547 Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683 216591024548 active site lid residues [active] 216591024549 substrate binding pocket [chemical binding]; other site 216591024550 catalytic residues [active] 216591024551 substrate-Mg2+ binding site; other site 216591024552 aspartate-rich region 1; other site 216591024553 aspartate-rich region 2; other site 216591024554 HMMPfam hit to PF00494, Squalene/phytoene synthase, score 8.7e-11 216591024555 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591024556 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591024557 trimer interface [polypeptide binding]; other site 216591024558 eyelet of channel; other site 216591024559 HMMPfam hit to PF00267, Gram-negative porin, score 2.9e-06 216591024560 Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917 216591024561 HMMPfam hit to PF07883, Cupin domain, score 8.2e-11 216591024562 Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627 216591024563 Uncharacterized conserved protein [Function unknown]; Region: COG2128 216591024564 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 3.1e-19 216591024565 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591024566 DNA-binding site [nucleotide binding]; DNA binding site 216591024567 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591024568 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591024569 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591024570 homodimer interface [polypeptide binding]; other site 216591024571 catalytic residue [active] 216591024572 HMMPfam hit to PF00155, Aminotransferase class I and II, score 4.3e-07 216591024573 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 2e-15 216591024574 Predicted helix-turn-helix motif with score 1211.000, SD 3.31 at aa 37-58, sequence PSTRDLAKQLGVSRKTTLDAFE 216591024575 putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074 216591024576 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591024577 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591024578 dimerization interface [polypeptide binding]; other site 216591024579 HMMPfam hit to PF01047, MarR family, score 0.0027 216591024580 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.8e-17 216591024581 Predicted helix-turn-helix motif with score 1466.000, SD 4.18 at aa 17-38, sequence GSLSRAAARLGKAPSTVSHAAR 216591024582 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.7e-20 216591024583 short chain dehydrogenase; Provisional; Region: PRK06500 216591024584 classical (c) SDRs; Region: SDR_c; cd05233 216591024585 NAD(P) binding site [chemical binding]; other site 216591024586 active site 216591024587 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.5e-26 216591024588 PS00061 Short-chain dehydrogenases/reductases family signature. 216591024589 Glycosyl hydrolases family 32; Region: Glyco_32; smart00640 216591024590 Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996 216591024591 substrate binding [chemical binding]; other site 216591024592 active site 216591024593 Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244 216591024594 HMMPfam hit to PF08244, Glycosyl hydrolases family 32 C termi, score 3.3e-15 216591024595 HMMPfam hit to PF00251, Glycosyl hydrolases family 32 N termi, score 5e-135 216591024596 PS00609 Glycosyl hydrolases family 32 active site. 216591024597 Glycosyl hydrolase family 68, includes levansucrase, beta-fructofuranosidase and inulosucrase; Region: GH68; cd08997 216591024598 active site 216591024599 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591024600 HMMPfam hit to PF02435, Levansucrase/Invertase, score 6.6e-199 216591024601 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591024602 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591024603 DNA binding site [nucleotide binding] 216591024604 domain linker motif; other site 216591024605 Ligand-binding domain of DNA transcription repressors specific for raffinose (RafR) and alpha-glucosides (AglR) which are members of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AglR_RafR_like; cd06271 216591024606 ligand binding site [chemical binding]; other site 216591024607 Predicted helix-turn-helix motif with score 2162.000, SD 6.55 at aa 3-24, sequence VNLKALSDALGLSRTTVSRALN 216591024608 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 5.9e-12 216591024609 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 216591024610 Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141 216591024611 potential catalytic triad [active] 216591024612 conserved cys residue [active] 216591024613 HMMPfam hit to PF01965, DJ-1/PfpI family, score 7.9e-25 216591024614 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 216591024615 Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis. Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932 216591024616 active site 216591024617 FMN binding site [chemical binding]; other site 216591024618 substrate binding site [chemical binding]; other site 216591024619 homotetramer interface [polypeptide binding]; other site 216591024620 catalytic residue [active] 216591024621 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 1.2e-69 216591024622 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628 216591024623 HMMPfam hit to PF01594, Domain of unknown function DUF20, score 4.1e-23 216591024624 9 probable transmembrane helices predicted for BCAM1409 by TMHMM2.0 at aa 20-37, 41-58, 71-93, 176-198, 218-240, 250-272, 277-299, 304-326 and 333-355 216591024625 SmpA / OmlA family; Region: SmpA_OmlA; cl17115 216591024626 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591024627 short chain dehydrogenase; Provisional; Region: PRK06523 216591024628 classical (c) SDRs; Region: SDR_c; cd05233 216591024629 NAD(P) binding site [chemical binding]; other site 216591024630 active site 216591024631 HMMPfam hit to PF00106, short chain dehydrogenase, score 9.1e-19 216591024632 Inclusion body protein; Region: PixA; pfam12306 216591024633 Inclusion body protein; Region: PixA; pfam12306 216591024634 Inclusion body protein; Region: PixA; pfam12306 216591024635 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 216591024636 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591024637 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591024638 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591024639 HMMPfam hit to PF02311, AraC-like ligand binding domain, score 1.1e-12 216591024640 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 5.4e-09 216591024641 Predicted helix-turn-helix motif with score 1162.000, SD 3.14 at aa 196-217, sequence VTLDAICAAADLSPSYLIRAFN 216591024642 PS00041 Bacterial regulatory proteins, araC family signature. 216591024643 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 4.5e-05 216591024644 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591024645 5 probable transmembrane helices predicted for BCAM1416 by TMHMM2.0 at aa 7-29, 39-61, 68-90, 142-164 and 176-193 216591024646 HMMPfam hit to PF01810, LysE type translocator, score 6e-14 216591024647 heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386 216591024648 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054 216591024649 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591024650 dimer interface [polypeptide binding]; other site 216591024651 phosphorylation site [posttranslational modification] 216591024652 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591024653 ATP binding site [chemical binding]; other site 216591024654 Mg2+ binding site [ion binding]; other site 216591024655 G-X-G motif; other site 216591024656 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.7e-25 216591024657 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.6e-17 216591024658 HMMPfam hit to PF00672, HAMP domain, score 1.3e-10 216591024659 2 probable transmembrane helices predicted for BCAM1417 by TMHMM2.0 at aa 10-32 and 156-178 216591024660 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591024661 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591024662 heavy metal response regulator; Region: cztR_silR_copR; TIGR01387 216591024663 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591024664 active site 216591024665 phosphorylation site [posttranslational modification] 216591024666 intermolecular recognition site; other site 216591024667 dimerization interface [polypeptide binding]; other site 216591024668 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591024669 DNA binding site [nucleotide binding] 216591024670 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1e-21 216591024671 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.2e-36 216591024672 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591024673 HMMPfam hit to PF02321, Outer membrane efflux protein, score 7.7e-39 216591024674 HMMPfam hit to PF02321, Outer membrane efflux protein, score 9.2e-26 216591024675 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591024676 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 216591024677 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591024678 HMMPfam hit to PF00529, HlyD family secretion protein, score 0.00079 216591024679 1 probable transmembrane helix predicted for BCAM1420 by TMHMM2.0 at aa 32-51 216591024680 Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841 216591024681 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 3.7e-162 216591024682 12 probable transmembrane helices predicted for BCAM1421 by TMHMM2.0 at aa 12-34, 331-353, 360-379, 383-400, 431-453, 468-490, 537-556, 883-905, 912-931, 936-958, 987-1009 and 1019-1041 216591024683 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 216591024684 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 216591024685 ligand binding site [chemical binding]; other site 216591024686 flexible hinge region; other site 216591024687 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 216591024688 Predicted helix-turn-helix motif with score 1923.000, SD 5.74 at aa 233-254, sequence ISQEELGMLVGVSRQRINQALQ 216591024689 HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 1.2e-11 216591024690 acyl-CoA synthetase; Validated; Region: PRK08162 216591024691 Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles and Arabidopsis; Region: ttLC_FACS_AEE21_like; cd12118 216591024692 acyl-activating enzyme (AAE) consensus motif; other site 216591024693 putative active site [active] 216591024694 AMP binding site [chemical binding]; other site 216591024695 putative CoA binding site [chemical binding]; other site 216591024696 HMMPfam hit to PF00501, AMP-binding enzyme, score 3e-97 216591024697 PS00455 Putative AMP-binding domain signature. 216591024698 Cache domain; Region: Cache_1; pfam02743 216591024699 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 216591024700 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591024701 dimer interface [polypeptide binding]; other site 216591024702 putative CheW interface [polypeptide binding]; other site 216591024703 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 1.7e-75 216591024704 HMMPfam hit to PF00672, HAMP domain, score 5e-09 216591024705 2 probable transmembrane helices predicted for BCAM1424 by TMHMM2.0 at aa 15-37 and 327-346 216591024706 Predicted membrane protein [Function unknown]; Region: COG1238 216591024707 4 probable transmembrane helices predicted for BCAM1425 by TMHMM2.0 at aa 7-25, 40-62, 96-115 and 119-141 216591024708 voltage-gated potassium channel; Provisional; Region: PRK10537 216591024709 Ion channel; Region: Ion_trans_2; pfam07885 216591024710 TrkA-N domain; Region: TrkA_N; pfam02254 216591024711 HMMPfam hit to PF02254, TrkA-N domain, score 6e-20 216591024712 7 probable transmembrane helices predicted for BCAM1426 by TMHMM2.0 at aa 11-33, 59-81, 88-107, 111-128, 135-157, 172-191 and 204-226 216591024713 HMMPfam hit to PF07885, Ion channel, score 5.4e-17 216591024714 HMMPfam hit to PF00520, Ion transport protein, score 0.012 216591024715 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591024716 HMMPfam hit to PF01810, LysE type translocator, score 2.8e-19 216591024717 4 probable transmembrane helices predicted for BCAM1427 by TMHMM2.0 at aa 5-27, 39-61, 160-182 and 202-217 216591024718 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591024719 Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412 216591024720 putative DNA binding site [nucleotide binding]; other site 216591024721 putative Zn2+ binding site [ion binding]; other site 216591024722 AsnC family; Region: AsnC_trans_reg; pfam01037 216591024723 Predicted helix-turn-helix motif with score 1381.000, SD 3.89 at aa 28-49, sequence LSNAELAEQIGMSTTACWNRTR 216591024724 PS00519 Bacterial regulatory proteins, asnC family signature. 216591024725 HMMPfam hit to PF01037, AsnC family, score 1.1e-27 216591024726 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591024727 IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339 216591024728 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591024729 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 4.2e-06 216591024730 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 5.7e-05 216591024731 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 216591024732 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 2e-17 216591024733 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591024734 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591024735 putative substrate translocation pore; other site 216591024736 12 probable transmembrane helices predicted for BCAM1431 by TMHMM2.0 at aa 42-64, 79-101, 108-127, 132-154, 167-189, 202-224, 270-292, 302-324, 336-353, 358-380, 387-409 and 424-446 216591024737 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.5e-53 216591024738 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591024739 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591024740 putative substrate translocation pore; other site 216591024741 12 probable transmembrane helices predicted for BCAM1432 by TMHMM2.0 at aa 29-46, 69-91, 103-125, 129-151, 158-180, 195-214, 261-283, 293-315, 328-345, 349-371, 378-400 and 415-437 216591024742 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1e-51 216591024743 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591024744 Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300 216591024745 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591024746 NAD(P) binding site [chemical binding]; other site 216591024747 active site 216591024748 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0006 216591024749 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.4e-32 216591024750 PS00061 Short-chain dehydrogenases/reductases family signature. 216591024751 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591024752 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 216591024753 conserved cys residue [active] 216591024754 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591024755 HMMPfam hit to PF01965, DJ-1/PfpI family, score 2.1e-09 216591024756 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.9e-06 216591024757 Predicted helix-turn-helix motif with score 1807.000, SD 5.34 at aa 226-247, sequence LTVEDLAEAVHLSPRQFSRIFT 216591024758 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 2.9e-06 216591024759 Epoxide hydrolase N terminus; Region: EHN; pfam06441 216591024760 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591024761 HMMPfam hit to PF06441, Epoxide hydrolase N terminus, score 6.2e-47 216591024762 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 0.00089 216591024763 ChrR Cupin-like domain; Region: Cupin_7; pfam12973 216591024764 HMMPfam hit to PF07883, Cupin domain, score 0.0024 216591024765 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591024766 MarR family; Region: MarR_2; cl17246 216591024767 HMMPfam hit to PF01047, MarR family, score 5.6e-08 216591024768 3 probable transmembrane helices predicted for BCAM1438 by TMHMM2.0 at aa 7-29, 44-66 and 79-98 216591024769 H+ Antiporter protein; Region: 2A0121; TIGR00900 216591024770 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591024771 putative substrate translocation pore; other site 216591024772 HMMPfam hit to PF05977, Bacterial protein of unknown function (DUF89, score 2.7e-07 216591024773 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.6e-41 216591024774 8 probable transmembrane helices predicted for BCAM1439 by TMHMM2.0 at aa 84-106, 165-187, 229-248, 263-282, 289-311, 315-337, 349-371 and 381-400 216591024775 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591024776 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591024777 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591024778 dimerization interface [polypeptide binding]; other site 216591024779 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.7e-24 216591024780 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.9e-10 216591024781 Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 33-54, sequence GGMAAAELELNIGISTISRHVK 216591024782 beta alanine--pyruvate transaminase; Provisional; Region: PRK09221 216591024783 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591024784 inhibitor-cofactor binding pocket; inhibition site 216591024785 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591024786 catalytic residue [active] 216591024787 HMMPfam hit to PF00202, Aminotransferase class-III, score 1.6e-121 216591024788 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591024789 Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085 216591024790 methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722 216591024791 tetrameric interface [polypeptide binding]; other site 216591024792 NAD binding site [chemical binding]; other site 216591024793 catalytic residues [active] 216591024794 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 5.2e-158 216591024795 Secreted repeat of unknown function; Region: Lipoprotein_15; pfam03640 216591024796 Secreted repeat of unknown function; Region: Lipoprotein_15; pfam03640 216591024797 HMMPfam hit to PF03640, Secreted repeat of unknown function, score 4.3e-17 216591024798 HMMPfam hit to PF03640, Secreted repeat of unknown function, score 4.3e-10 216591024799 EamA-like transporter family; Region: EamA; pfam00892 216591024800 EamA-like transporter family; Region: EamA; pfam00892 216591024801 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.9e-27 216591024802 9 probable transmembrane helices predicted for BCAM1444 by TMHMM2.0 at aa 20-42, 49-66, 81-103, 110-129, 134-153, 197-219, 229-251, 264-283 and 287-304 216591024803 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 3.2e-23 216591024804 Predicted permeases [General function prediction only]; Region: COG0679 216591024805 9 probable transmembrane helices predicted for BCAM1445 by TMHMM2.0 at aa 26-48, 87-109, 124-146, 151-173, 188-210, 217-239, 249-271, 278-300 and 310-332 216591024806 HMMPfam hit to PF03547, Auxin Efflux Carrier, score 8.2e-08 216591024807 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591024808 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591024809 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_2; cd08427 216591024810 putative dimerization interface [polypeptide binding]; other site 216591024811 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-31 216591024812 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 7.1e-18 216591024813 PS00044 Bacterial regulatory proteins, lysR family signature. 216591024814 Predicted helix-turn-helix motif with score 1578.000, SD 4.56 at aa 16-37, sequence RTFARAGEAIGLTQSAVSLQIK 216591024815 SnoaL-like domain; Region: SnoaL_2; pfam12680 216591024816 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591024817 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591024818 DNA binding residues [nucleotide binding] 216591024819 dimerization interface [polypeptide binding]; other site 216591024820 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 3.6e-19 216591024821 PS00622 Bacterial regulatory proteins, luxR family signature. 216591024822 Predicted helix-turn-helix motif with score 1225.000, SD 3.36 at aa 217-238, sequence NSSKAIAERLAISPETVKVHRR 216591024823 amino acid transporter; Region: 2A0306; TIGR00909 216591024824 HMMPfam hit to PF00324, Amino acid permease, score 5e-06 216591024825 12 probable transmembrane helices predicted for BCAM1449A by TMHMM2.0 at aa 33-55, 59-81, 102-124, 139-161, 166-188, 208-230, 251-273, 305-327, 348-370, 375-397, 410-432 and 442-459 216591024826 L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active...; Region: DmpA; cd02253 216591024827 homodimer interface [polypeptide binding]; other site 216591024828 homotetramer interface [polypeptide binding]; other site 216591024829 active site pocket [active] 216591024830 cleavage site 216591024831 HMMPfam hit to PF03576, Peptidase family T4, score 3.2e-92 216591024832 Fusaric acid resistance protein family; Region: FUSC; pfam04632 216591024833 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 216591024834 10 probable transmembrane helices predicted for BCAM1452 by TMHMM2.0 at aa 37-59, 86-108, 113-130, 137-159, 169-191, 400-422, 451-473, 480-499, 504-526 and 531-553 216591024835 HMMPfam hit to PF04632, Fusaric acid resistance protein conserved re, score 5.5e-25 216591024836 transcriptional regulator; Provisional; Region: PRK10632 216591024837 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591024838 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591024839 putative effector binding pocket; other site 216591024840 dimerization interface [polypeptide binding]; other site 216591024841 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.5e-15 216591024842 Predicted helix-turn-helix motif with score 1122.000, SD 3.01 at aa 17-38, sequence GSFTAAAQSLNSTTGAMSRAVS 216591024843 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.6e-42 216591024844 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591024845 1 probable transmembrane helix predicted for BCAM1454 by TMHMM2.0 at aa 4-22 216591024846 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591024847 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591024848 trimer interface [polypeptide binding]; other site 216591024849 eyelet of channel; other site 216591024850 HMMPfam hit to PF00267, Gram-negative porin, score 5.1e-05 216591024851 PS00572 Glycosyl hydrolases family 1 active site. 216591024852 Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293 216591024853 cytosine deaminase; Provisional; Region: PRK09230 216591024854 active site 216591024855 HMMPfam hit to PF07969, Amidohydrolase family, score 7.4e-64 216591024856 Putative ClC chloride channel. Clc proteins are putative halogen ion (Cl-, Br- and I-) transporters found in eubacteria. They belong to the ClC superfamily of halogen ion channels, which share a unique double-barreled architecture and voltage-dependent...; Region: ClC_like; cd01033 216591024857 Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038 216591024858 putative ion selectivity filter; other site 216591024859 putative pore gating glutamate residue; other site 216591024860 9 probable transmembrane helices predicted for BCAM1458 by TMHMM2.0 at aa 22-44, 78-96, 176-198, 205-224, 239-261, 273-295, 305-327, 340-362 and 372-394 216591024861 HMMPfam hit to PF00654, Voltage gated chloride channel, score 5.6e-09 216591024862 Short chain fatty acid transporter; Region: SCFA_trans; cl17380 216591024863 HMMPfam hit to PF02667, Short chain fatty acid transporter score 2.1e-248 216591024864 10 probable transmembrane helices predicted for BCAM1459 by TMHMM2.0 at aa 20-39, 54-76, 97-119, 139-161, 182-204, 245-262, 275-297, 307-329, 336-358 and 417-439 216591024865 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591024866 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591024867 putative substrate translocation pore; other site 216591024868 12 probable transmembrane helices predicted for BCAM1460 by TMHMM2.0 at aa 23-41, 56-78, 91-113, 123-145, 152-174, 184-206, 256-278, 288-310, 323-340, 344-366, 379-401 and 411-429 216591024869 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.1e-45 216591024870 Prokaryotic protein of unknown function (DUF849); Region: DUF849; pfam05853 216591024871 HMMPfam hit to PF05853, Prokaryotic protein of unknown function (DUF, score 1.7e-170 216591024872 short chain dehydrogenase; Provisional; Region: PRK12829 216591024873 classical (c) SDRs; Region: SDR_c; cd05233 216591024874 NAD(P) binding site [chemical binding]; other site 216591024875 active site 216591024876 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.003 216591024877 PS00196 Type-1 copper (blue) proteins signature. 216591024878 HMMPfam hit to PF00106, short chain dehydrogenase, score 8.7e-25 216591024879 PS00061 Short-chain dehydrogenases/reductases family signature. 216591024880 Transcriptional regulators [Transcription]; Region: GntR; COG1802 216591024881 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414 216591024882 FCD domain; Region: FCD; pfam07729 216591024883 HMMPfam hit to PF07729, FCD domain, score 1e-18 216591024884 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 4.1e-15 216591024885 Predicted helix-turn-helix motif with score 1092.000, SD 2.91 at aa 41-62, sequence LSLRSVAEAVGSSTMPVRAALT 216591024886 Domain of unknown function (DUF4285); Region: DUF4285; pfam14113 216591024887 CagZ; Region: CagZ; pfam09053 216591024888 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 216591024889 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591024890 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591024891 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 1.9e-34 216591024892 Predicted helix-turn-helix motif with score 1596.000, SD 4.62 at aa 34-55, sequence MTLAEVADAAGMTKSSAQRMVY 216591024893 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591024894 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591024895 substrate binding pocket [chemical binding]; other site 216591024896 membrane-bound complex binding site; other site 216591024897 hinge residues; other site 216591024898 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.1e-52 216591024899 PS00017 ATP/GTP-binding site motif A (P-loop). 216591024900 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591024901 dimer interface [polypeptide binding]; other site 216591024902 conserved gate region; other site 216591024903 putative PBP binding loops; other site 216591024904 ABC-ATPase subunit interface; other site 216591024905 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3.7e-27 216591024906 3 probable transmembrane helices predicted for BCAM1468 by TMHMM2.0 at aa 19-41, 54-76 and 184-206 216591024907 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591024908 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 216591024909 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 216591024910 Walker A/P-loop; other site 216591024911 ATP binding site [chemical binding]; other site 216591024912 Q-loop/lid; other site 216591024913 ABC transporter signature motif; other site 216591024914 Walker B; other site 216591024915 D-loop; other site 216591024916 H-loop/switch region; other site 216591024917 HMMPfam hit to PF00005, ABC transporter score 4.2e-67 216591024918 PS00017 ATP/GTP-binding site motif A (P-loop). 216591024919 PS00211 ABC transporters family signature. 216591024920 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591024921 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591024922 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.8e-91 216591024923 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 216591024924 This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811 216591024925 putative ADP-binding pocket [chemical binding]; other site 216591024926 HMMPfam hit to PF00534, Glycosyl transferases group, score 2.1e-44 216591024927 Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858 216591024928 PS00190 Cytochrome c family heme-binding site signature. 216591024929 HMMPfam hit to PF03150, Di-haem cytochrome c peroxidase, score 6.5e-13 216591024930 PS00190 Cytochrome c family heme-binding site signature. 216591024931 Phosphoesterase family; Region: Phosphoesterase; pfam04185 216591024932 HMMPfam hit to PF04185, Phosphoesterase family, score 7.5e-70 216591024933 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591024934 phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340 216591024935 Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910 216591024936 EamA-like transporter family; Region: EamA; pfam00892 216591024937 10 probable transmembrane helices predicted for BCAM1475 by TMHMM2.0 at aa 4-26, 38-57, 61-83, 90-112, 117-135, 148-170, 175-197, 210-232, 242-259 and 268-287 216591024938 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.9e-11 216591024939 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591024940 AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404 216591024941 putative DNA binding site [nucleotide binding]; other site 216591024942 putative Zn2+ binding site [ion binding]; other site 216591024943 AsnC family; Region: AsnC_trans_reg; pfam01037 216591024944 HMMPfam hit to PF01037, AsnC family, score 7.8e-26 216591024945 aromatic amino acid transporter; Provisional; Region: PRK10238 216591024946 HMMPfam hit to PF00324, Amino acid permease, score 5.7e-147 216591024947 12 probable transmembrane helices predicted for BCAM1477 by TMHMM2.0 at aa 21-40, 44-66, 86-108, 118-140, 153-175, 198-220, 240-262, 277-299, 331-353, 357-379, 399-421 and 426-443 216591024948 PS00218 Amino acid permeases signature. 216591024949 aromatic amino acid aminotransferase; Provisional; Region: PRK09257 216591024950 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591024951 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591024952 homodimer interface [polypeptide binding]; other site 216591024953 catalytic residue [active] 216591024954 HMMPfam hit to PF00155, Aminotransferase class I and II, score 7.2e-113 216591024955 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 216591024956 Protein of unknown function, DUF488; Region: DUF488; cl01246 216591024957 Protein of unknown function (DUF1488); Region: DUF1488; pfam07369 216591024958 PS00153 ATP synthase gamma subunit signature. 216591024959 fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161 216591024960 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 216591024961 ligand binding site [chemical binding]; other site 216591024962 flexible hinge region; other site 216591024963 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 216591024964 putative switch regulator; other site 216591024965 non-specific DNA interactions [nucleotide binding]; other site 216591024966 DNA binding site [nucleotide binding] 216591024967 sequence specific DNA binding site [nucleotide binding]; other site 216591024968 putative cAMP binding site [chemical binding]; other site 216591024969 HMMPfam hit to PF00325, Bacterial regulatory proteins, crp famil, score 2.8e-09 216591024970 Predicted helix-turn-helix motif with score 1839.000, SD 5.45 at aa 212-233, sequence MTREEIGCYLGMKLETVSRMFS 216591024971 HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 3.3e-15 216591024972 Response regulator receiver domain; Region: Response_reg; pfam00072 216591024973 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591024974 active site 216591024975 phosphorylation site [posttranslational modification] 216591024976 intermolecular recognition site; other site 216591024977 dimerization interface [polypeptide binding]; other site 216591024978 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.6e-19 216591024979 ornithine cyclodeaminase; Validated; Region: PRK07340 216591024980 ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400 216591024981 HMMPfam hit to PF02423, Ornithine cyclodeaminase/mu-crystalli, score 1.1e-11 216591024982 Transcriptional regulators [Transcription]; Region: FadR; COG2186 216591024983 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591024984 DNA-binding site [nucleotide binding]; DNA binding site 216591024985 FCD domain; Region: FCD; pfam07729 216591024986 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 3.3e-25 216591024987 PS00043 Bacterial regulatory proteins, gntR family signature. 216591024988 HMMPfam hit to PF07729, FCD domain, score 3.6e-16 216591024989 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591024990 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 216591024991 dimerization interface [polypeptide binding]; other site 216591024992 ligand binding site [chemical binding]; other site 216591024993 HMMPfam hit to PF01094, Receptor family ligand binding region, score 2.2e-48 216591024994 hydroxyproline-2-epimerase; Provisional; Region: PRK13971 216591024995 Proline racemase; Region: Pro_racemase; pfam05544 216591024996 HMMPfam hit to PF05544, Proline racemase, score 2.9e-130 216591024997 Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744 216591024998 Transglycosylase; Region: Transgly; pfam00912 216591024999 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 216591025000 1 probable transmembrane helix predicted for BCAM1489 by TMHMM2.0 at aa 45-67 216591025001 HMMPfam hit to PF00912, Transglycosylase, score 5.5e-82 216591025002 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 3.7e-27 216591025003 PilZ domain; Region: PilZ; pfam07238 216591025004 HMMPfam hit to PF07238, PilZ domain, score 1.1e-13 216591025005 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591025006 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755 216591025007 HMMPfam hit to PF07007, Protein of unknown function (DUF1311), score 4.5e-26 216591025008 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591025009 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591025010 active site 216591025011 phosphorylation site [posttranslational modification] 216591025012 intermolecular recognition site; other site 216591025013 dimerization interface [polypeptide binding]; other site 216591025014 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591025015 DNA binding residues [nucleotide binding] 216591025016 dimerization interface [polypeptide binding]; other site 216591025017 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 1.8e-17 216591025018 Predicted helix-turn-helix motif with score 1561.000, SD 4.50 at aa 164-185, sequence QTLTEIANALCVSAKTVSTYKT 216591025019 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.4e-37 216591025020 PAS domain S-box; Region: sensory_box; TIGR00229 216591025021 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591025022 putative active site [active] 216591025023 heme pocket [chemical binding]; other site 216591025024 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920 216591025025 Histidine kinase; Region: HisKA_3; pfam07730 216591025026 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591025027 ATP binding site [chemical binding]; other site 216591025028 Mg2+ binding site [ion binding]; other site 216591025029 G-X-G motif; other site 216591025030 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.9e-18 216591025031 HMMPfam hit to PF07730, Histidine kinase, score 4.6e-18 216591025032 HMMPfam hit to PF08448, PAS fold, score 1.1e-09 216591025033 HMMPfam hit to PF00989, PAS fold, score 8.2e-13 216591025034 2 probable transmembrane helices predicted for BCAM1494 by TMHMM2.0 at aa 24-46 and 303-325 216591025035 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591025036 Ligand Binding Site [chemical binding]; other site 216591025037 HMMPfam hit to PF00582, Universal stress protein family, score 3.9e-27 216591025038 Cupin superfamily (DUF985); Region: Cupin_5; pfam06172 216591025039 HMMPfam hit to PF06172, Cupin superfamily (DUF985), score 2.2e-62 216591025040 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 216591025041 SNARE associated Golgi protein; Region: SNARE_assoc; cl00429 216591025042 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125 216591025043 active site residue [active] 216591025044 5 probable transmembrane helices predicted for BCAM1497 by TMHMM2.0 at aa 15-37, 50-72, 104-126, 131-153 and 168-190 216591025045 This CDS appears to have a frameshift mutation at codon 306 216591025046 HMMPfam hit to PF00324, Amino acid permease, score 8.9e-150 216591025047 12 probable transmembrane helices predicted for BCAM1498 by TMHMM2.0 at aa 16-38, 42-64, 84-106, 121-143, 155-177, 197-219, 240-262, 282-304, 331-353, 357-379, 400-422 and 427-449 216591025048 PS00218 Amino acid permeases signature. 216591025049 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591025050 Ligand Binding Site [chemical binding]; other site 216591025051 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591025052 Ligand Binding Site [chemical binding]; other site 216591025053 HMMPfam hit to PF00582, Universal stress protein family, score 1.6e-16 216591025054 Protein of unknown function (DUF3562); Region: DUF3562; pfam12085 216591025055 Cache domain; Region: Cache_1; pfam02743 216591025056 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591025057 dimerization interface [polypeptide binding]; other site 216591025058 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 216591025059 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591025060 dimer interface [polypeptide binding]; other site 216591025061 putative CheW interface [polypeptide binding]; other site 216591025062 2 probable transmembrane helices predicted for BCAM1503 by TMHMM2.0 at aa 10-32 and 271-293 216591025063 HMMPfam hit to PF02743, Cache domain, score 6.1e-21 216591025064 HMMPfam hit to PF00672, HAMP domain, score 2.4e-18 216591025065 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 9.5e-91 216591025066 psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974 216591025067 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591025068 Walker A motif; other site 216591025069 ATP binding site [chemical binding]; other site 216591025070 Walker B motif; other site 216591025071 arginine finger; other site 216591025072 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591025073 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 6.1e-07 216591025074 Predicted helix-turn-helix motif with score 1411.000, SD 3.99 at aa 395-416, sequence GNKPRAAKALGISLKTLYNRLA 216591025075 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591025076 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 4.1e-122 216591025077 HMMPfam hit to PF07728, ATPase family associated with various, score 6.1e-05 216591025078 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591025079 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 216591025080 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591025081 putative active site [active] 216591025082 heme pocket [chemical binding]; other site 216591025083 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591025084 dimer interface [polypeptide binding]; other site 216591025085 phosphorylation site [posttranslational modification] 216591025086 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591025087 ATP binding site [chemical binding]; other site 216591025088 Mg2+ binding site [ion binding]; other site 216591025089 G-X-G motif; other site 216591025090 Response regulator receiver domain; Region: Response_reg; pfam00072 216591025091 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591025092 active site 216591025093 phosphorylation site [posttranslational modification] 216591025094 intermolecular recognition site; other site 216591025095 dimerization interface [polypeptide binding]; other site 216591025096 3 probable transmembrane helices predicted for BCAM1505 by TMHMM2.0 at aa 12-34, 54-76 and 83-105 216591025097 HMMPfam hit to PF00989, PAS fold, score 5.9e-10 216591025098 HMMPfam hit to PF08448, PAS fold, score 0.0028 216591025099 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 8.9e-19 216591025100 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 5.5e-43 216591025101 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.7e-28 216591025102 BON domain; Region: BON; pfam04972 216591025103 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025104 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 2.5e-14 216591025105 2 probable transmembrane helices predicted for BCAM1507 by TMHMM2.0 at aa 63-85 and 90-112 216591025106 Domain of unknown function (DUF4142); Region: DUF4142; pfam13628 216591025107 PRC-barrel domain; Region: PRC; pfam05239 216591025108 HMMPfam hit to PF05239, PRC-barrel domain, score 5.4e-16 216591025109 FOG: CBS domain [General function prediction only]; Region: COG0517 216591025110 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_9; cd04622 216591025111 HMMPfam hit to PF00571, CBS domain pair, score 5.6e-30 216591025112 Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713 216591025113 HMMPfam hit to PF06629, MltA-interacting protein MipA, score 5.1e-40 216591025114 This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990 216591025115 Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199 216591025116 DEAD_2; Region: DEAD_2; pfam06733 216591025117 Helicase C-terminal domain; Region: Helicase_C_2; pfam13307 216591025118 PS00017 ATP/GTP-binding site motif A (P-loop). 216591025119 PS00030 Eukaryotic putative RNA-binding region RNP-1 signature. 216591025120 beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Region: pcaR_pcaU; TIGR02431 216591025121 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 216591025122 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591025123 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 6.6e-21 216591025124 Predicted helix-turn-helix motif with score 1286.000, SD 3.57 at aa 33-54, sequence MTPTQAAARTGLTRTAARRYLL 216591025125 This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288 216591025126 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072 216591025127 putative active site [active] 216591025128 Predicted restriction endonuclease [Defense mechanisms]; Region: COG3183 216591025129 HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085 216591025130 active site 216591025131 HMMPfam hit to PF01844, HNH endonuclease, score 1.8e-06 216591025132 shikimate transporter; Provisional; Region: PRK09952 216591025133 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591025134 putative substrate translocation pore; other site 216591025135 HMMPfam hit to PF00083, Sugar (and other) transporter score 1.3e-11 216591025136 12 probable transmembrane helices predicted for BCAM1521 by TMHMM2.0 at aa 25-47, 62-84, 97-119, 129-151, 164-186, 196-215, 250-272, 287-309, 314-336, 341-360, 381-403 and 407-429 216591025137 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.7e-24 216591025138 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [Amino acid transport and metabolism / General function prediction only]; Region: COG3185 216591025139 N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342 216591025140 dimer interface [polypeptide binding]; other site 216591025141 C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250 216591025142 active site 216591025143 Fe binding site [ion binding]; other site 216591025144 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 1.3e-08 216591025145 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 216591025146 Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803 216591025147 active site 216591025148 FMN binding site [chemical binding]; other site 216591025149 substrate binding site [chemical binding]; other site 216591025150 putative catalytic residue [active] 216591025151 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 5.7e-37 216591025152 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Provisional; Region: PRK14019 216591025153 3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926 216591025154 GTP cyclohydrolase II; Region: GTP_cyclohydro2; pfam00925 216591025155 dimerization interface [polypeptide binding]; other site 216591025156 active site 216591025157 HMMPfam hit to PF00925, GTP cyclohydrolase II, score 1.3e-06 216591025158 HMMPfam hit to PF00926, 3,4-dihydroxy-2-butanone 4-phosphate, score 1.7e-110 216591025159 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 216591025160 HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 1.1e-94 216591025161 PS01174 Lipolytic enzymes G-D-X-G family, putative serine active site. 216591025162 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315 216591025163 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 6.3e-05 216591025164 Predicted helix-turn-helix motif with score 1714.000, SD 5.02 at aa 358-379, sequence LTLEEAADESGISKNTARTHLR 216591025165 HMMPfam hit to PF01545, Cation efflux family, score 5.8e-07 216591025166 6 probable transmembrane helices predicted for BCAM1527 by TMHMM2.0 at aa 21-40, 44-66, 79-101, 116-138, 161-178 and 183-200 216591025167 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3224 216591025168 2 probable transmembrane helices predicted for BCAM1528 by TMHMM2.0 at aa 111-133 and 140-162 216591025169 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591025170 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591025171 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 3.3e-10 216591025172 C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526 216591025173 Interphotoreceptor retinoid-binding protein; serine protease family S41; Region: Peptidase_S41_IRBP; cd07563 216591025174 active site triad [active] 216591025175 HMMPfam hit to PF03572, Peptidase family S41, score 8.7e-19 216591025176 Domain of unknown function (DUF4156); Region: DUF4156; pfam13698 216591025177 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025178 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591025179 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591025180 active site 216591025181 phosphorylation site [posttranslational modification] 216591025182 intermolecular recognition site; other site 216591025183 dimerization interface [polypeptide binding]; other site 216591025184 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591025185 DNA binding residues [nucleotide binding] 216591025186 dimerization interface [polypeptide binding]; other site 216591025187 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 2.8e-23 216591025188 PS00622 Bacterial regulatory proteins, luxR family signature. 216591025189 Predicted helix-turn-helix motif with score 1152.000, SD 3.11 at aa 166-187, sequence GSNARIAATLGITEKTVKTHLG 216591025190 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.3e-31 216591025191 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 216591025192 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591025193 dimerization interface [polypeptide binding]; other site 216591025194 Histidine kinase; Region: HisKA_3; pfam07730 216591025195 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591025196 ATP binding site [chemical binding]; other site 216591025197 Mg2+ binding site [ion binding]; other site 216591025198 G-X-G motif; other site 216591025199 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2.3e-05 216591025200 HMMPfam hit to PF07730, Histidine kinase, score 4.2e-09 216591025201 HMMPfam hit to PF00672, HAMP domain, score 1.7e-13 216591025202 3 probable transmembrane helices predicted for BCAM1533 by TMHMM2.0 at aa 15-37, 155-177 and 192-214 216591025203 Plasmid replication region DNA-binding N-term; Region: KfrA_N; pfam11740 216591025204 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025205 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591025206 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591025207 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 4.9e-13 216591025208 Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130 216591025209 Prostaglandin dehydrogenases; Region: PGDH; cd05288 216591025210 NAD(P) binding site [chemical binding]; other site 216591025211 substrate binding site [chemical binding]; other site 216591025212 dimer interface [polypeptide binding]; other site 216591025213 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 0.0083 216591025214 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 8.2e-23 216591025215 Uncharacterized conserved protein [Function unknown]; Region: COG1359 216591025216 HMMPfam hit to PF03992, Antibiotic biosynthesis monooxygenase, score 5.3e-20 216591025217 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080 216591025218 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591025219 catalytic loop [active] 216591025220 iron binding site [ion binding]; other site 216591025221 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 216591025222 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 2.7e-09 216591025223 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591025224 HMMPfam hit to PF01799, [2Fe-2S] binding domain, score 2.6e-34 216591025225 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591025226 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 216591025227 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 216591025228 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591025229 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591025230 HMMPfam hit to PF02738, Aldehyde oxidase and xanthine dehydroge, score 8.9e-09 216591025231 PS00187 Thiamine pyrophosphate enzymes signature. 216591025232 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591025233 Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442 216591025234 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591025235 PS00190 Cytochrome c family heme-binding site signature. 216591025236 PS00190 Cytochrome c family heme-binding site signature. 216591025237 HMMPfam hit to PF00034, Cytochrome c, score 4.6e-08 216591025238 PS00190 Cytochrome c family heme-binding site signature. 216591025239 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591025240 Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103 216591025241 tetramerization interface [polypeptide binding]; other site 216591025242 NAD(P) binding site [chemical binding]; other site 216591025243 catalytic residues [active] 216591025244 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 4.2e-209 216591025245 Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532 216591025246 HMMPfam hit to PF01755, Glycosyltransferase family 25 (LPS bi, score 1.3e-13 216591025247 Probable gene remnant. Similar to the N-terminal region of Escherichia coli putative transposase UniProt:Q5DQF4 (EMBL:AY545598 (479 aa) fasta scores: E()=2e-31, 55.952% id in 168 aa 216591025248 Predicted helix-turn-helix motif with score 1201.000, SD 3.28 at aa 28-49, sequence LKPWRAAERLELTTRQVRRLVA 216591025249 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154 216591025250 Amidase; Region: Amidase; cl11426 216591025251 HMMPfam hit to PF01425, Amidase, score 1.8e-78 216591025252 PS00571 Amidases signature. 216591025253 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591025254 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591025255 DNA binding residues [nucleotide binding] 216591025256 dimerization interface [polypeptide binding]; other site 216591025257 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 2.9e-11 216591025258 HMMPfam hit to PF04967, HTH DNA binding domain, score 0.0034 216591025259 Predicted helix-turn-helix motif with score 1630.000, SD 4.74 at aa 293-314, sequence CTYKGVAKRLGIAPATARHHLR 216591025260 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591025261 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_8; cd07246 216591025262 putative dimer interface [polypeptide binding]; other site 216591025263 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591025264 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 3.3e-15 216591025265 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591025266 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591025267 trimer interface [polypeptide binding]; other site 216591025268 eyelet of channel; other site 216591025269 HMMPfam hit to PF00267, Gram-negative porin, score 2.8e-05 216591025270 putative outer membrane lipoprotein; Provisional; Region: PRK09967 216591025271 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591025272 ligand binding site [chemical binding]; other site 216591025273 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025274 HMMPfam hit to PF00691, OmpA family, score 1.6e-44 216591025275 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591025276 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591025277 Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442 216591025278 HMMPfam hit to PF00034, Cytochrome c, score 8.3e-10 216591025279 PS00190 Cytochrome c family heme-binding site signature. 216591025280 PS00190 Cytochrome c family heme-binding site signature. 216591025281 PS00190 Cytochrome c family heme-binding site signature. 216591025282 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025283 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080 216591025284 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 216591025285 HMMPfam hit to PF01799, [2Fe-2S] binding domain, score 1.5e-16 216591025286 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 0.0016 216591025287 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 216591025288 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591025289 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 216591025290 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591025291 HMMPfam hit to PF02738, Aldehyde oxidase and xanthine dehydroge, score 1.1e-14 216591025292 Predicted helix-turn-helix motif with score 973.000, SD 2.50 at aa 731-752, sequence EQLAKQAHALGLPTGAVVHVFN 216591025293 1 probable transmembrane helix predicted for BCAM1553 by TMHMM2.0 at aa 33-55 216591025294 PAS domain; Region: PAS; smart00091 216591025295 PAS fold; Region: PAS_7; pfam12860 216591025296 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591025297 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591025298 metal binding site [ion binding]; metal-binding site 216591025299 active site 216591025300 I-site; other site 216591025301 5 probable transmembrane helices predicted for BCAM1554 by TMHMM2.0 at aa 40-59, 63-82, 103-125, 129-151 and 160-182 216591025302 HMMPfam hit to PF00990, GGDEF domain, score 9.3e-51 216591025303 ectoine utilization protein EutE; Region: ectoine_eutE; TIGR02994 216591025304 Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup; Region: M14_ASTE_ASPA_like_2; cd06252 216591025305 putative active site [active] 216591025306 Zn binding site [ion binding]; other site 216591025307 HMMPfam hit to PF04952, Succinylglutamate desuccinylase / Aspartoac, score 5.1e-59 216591025308 Uncharacterized protein family UPF0547; Region: UPF0547; pfam10571 216591025309 Double zinc ribbon; Region: DZR; pfam12773 216591025310 4 probable transmembrane helices predicted for BCAM1557 by TMHMM2.0 at aa 15-37, 187-206, 211-233 and 240-259 216591025311 recombination associated protein; Reviewed; Region: rdgC; PRK00321 216591025312 HMMPfam hit to PF04381, Putative exonuclease, RdgC, score 3e-88 216591025313 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 216591025314 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591025315 Coenzyme A binding pocket [chemical binding]; other site 216591025316 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.4e-14 216591025317 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591025318 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591025319 substrate binding pocket [chemical binding]; other site 216591025320 membrane-bound complex binding site; other site 216591025321 hinge residues; other site 216591025322 1 probable transmembrane helix predicted for BCAM1560 by TMHMM2.0 at aa 12-34 216591025323 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 3.9e-33 216591025324 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347 216591025325 luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558 216591025326 probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858 216591025327 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 8.6e-09 216591025328 FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860 216591025329 nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095 216591025330 active site 216591025331 non-prolyl cis peptide bond; other site 216591025332 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591025333 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591025334 dimer interface [polypeptide binding]; other site 216591025335 conserved gate region; other site 216591025336 putative PBP binding loops; other site 216591025337 ABC-ATPase subunit interface; other site 216591025338 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 216591025339 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 216591025340 Walker A/P-loop; other site 216591025341 ATP binding site [chemical binding]; other site 216591025342 Q-loop/lid; other site 216591025343 ABC transporter signature motif; other site 216591025344 Walker B; other site 216591025345 D-loop; other site 216591025346 H-loop/switch region; other site 216591025347 5 probable transmembrane helices predicted for BCAM1563 by TMHMM2.0 at aa 41-63, 83-105, 118-140, 231-253 and 266-288 216591025348 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.3e-22 216591025349 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591025350 HMMPfam hit to PF00005, ABC transporter score 2.4e-70 216591025351 PS00017 ATP/GTP-binding site motif A (P-loop). 216591025352 PS00211 ABC transporters family signature. 216591025353 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591025354 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591025355 substrate binding pocket [chemical binding]; other site 216591025356 membrane-bound complex binding site; other site 216591025357 hinge residues; other site 216591025358 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 2e-15 216591025359 Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094 216591025360 active site 216591025361 alkanesulfonate monooxygenase, FMNH(2)-dependent; Region: alk_sulf_monoox; TIGR03565 216591025362 dimer interface [polypeptide binding]; other site 216591025363 non-prolyl cis peptide bond; other site 216591025364 insertion regions; other site 216591025365 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 3.3e-07 216591025366 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 216591025367 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591025368 substrate binding pocket [chemical binding]; other site 216591025369 membrane-bound complex binding site; other site 216591025370 Predicted alpha/beta hydrolase [General function prediction only]; Region: COG4757 216591025371 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591025372 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591025373 MarR family; Region: MarR; pfam01047 216591025374 HMMPfam hit to PF01047, MarR family, score 3.8e-13 216591025375 Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698 216591025376 Asp-box motif; other site 216591025377 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 16 216591025378 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.1 216591025379 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.31 216591025380 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.11 216591025381 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.43 216591025382 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 8.3 216591025383 Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064 216591025384 Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297 216591025385 NAD binding site [chemical binding]; other site 216591025386 substrate binding site [chemical binding]; other site 216591025387 catalytic Zn binding site [ion binding]; other site 216591025388 tetramer interface [polypeptide binding]; other site 216591025389 structural Zn binding site [ion binding]; other site 216591025390 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 6.4e-41 216591025391 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 1.4e-48 216591025392 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591025393 TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786 216591025394 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591025395 N-terminal plug; other site 216591025396 ligand-binding site [chemical binding]; other site 216591025397 PS00228 Tubulin-beta mRNA autoregulation signal. 216591025398 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 6.6e-18 216591025399 HMMPfam hit to PF00593, TonB dependent receptor, score 6.6e-21 216591025400 PS01156 TonB-dependent receptor proteins signature 2. 216591025401 Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729 216591025402 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 216591025403 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591025404 dimerization interface [polypeptide binding]; other site 216591025405 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591025406 dimer interface [polypeptide binding]; other site 216591025407 putative CheW interface [polypeptide binding]; other site 216591025408 1 probable transmembrane helix predicted for BCAM1572 by TMHMM2.0 at aa 12-31 216591025409 HMMPfam hit to PF00672, HAMP domain, score 3.9e-12 216591025410 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 2.3e-87 216591025411 Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788 216591025412 alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400 216591025413 active site 216591025414 homotetramer interface [polypeptide binding]; other site 216591025415 HMMPfam hit to PF00982, Glycosyltransferase family, score 1.1e-161 216591025416 FtsH Extracellular; Region: FtsH_ext; pfam06480 216591025417 ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241 216591025418 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591025419 Walker A motif; other site 216591025420 ATP binding site [chemical binding]; other site 216591025421 Walker B motif; other site 216591025422 arginine finger; other site 216591025423 Peptidase family M41; Region: Peptidase_M41; pfam01434 216591025424 HMMPfam hit to PF01434, Peptidase family M41, score 9.3e-93 216591025425 HMMPfam hit to PF00004, ATPase family associated with various c, score 4.1e-90 216591025426 PS00674 AAA-protein family signature. 216591025427 3 probable transmembrane helices predicted for BCAM1575 by TMHMM2.0 at aa 7-29, 117-139 and 226-248 216591025428 PS00017 ATP/GTP-binding site motif A (P-loop). 216591025429 HMMPfam hit to PF06480, FtsH Extracellular, score 3.8e-20 216591025430 Phospholipase C [Cell envelope biogenesis, outer membrane]; Region: PlcC; COG3511 216591025431 acid phosphatase, Burkholderia-type; Region: acid_phos_Burk; TIGR03397 216591025432 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025433 HMMPfam hit to PF04185, Phosphoesterase family, score 4.3e-194 216591025434 hypothetical protein; Validated; Region: PRK07121 216591025435 putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834 216591025436 putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834 216591025437 HMMPfam hit to PF00890, FAD binding domain, score 8.1e-37 216591025438 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 6.1e-05 216591025439 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025440 SnoaL-like domain; Region: SnoaL_4; pfam13577 216591025441 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 216591025442 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591025443 NAD(P) binding site [chemical binding]; other site 216591025444 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591025445 active site 216591025446 active site 216591025447 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 1.9e-07 216591025448 HMMPfam hit to PF07993, Male sterility protein, score 0.0024 216591025449 Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819 216591025450 active site 216591025451 substrate-binding site [chemical binding]; other site 216591025452 metal-binding site [ion binding] 216591025453 GTP binding site [chemical binding]; other site 216591025454 HMMPfam hit to PF00821, Phosphoenolpyruvate carboxykinase, score 0 216591025455 PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 216591025456 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591025457 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 216591025458 NAD(P) binding site [chemical binding]; other site 216591025459 active site 216591025460 HMMPfam hit to PF00106, short chain dehydrogenase, score 7.9e-33 216591025461 PS00061 Short-chain dehydrogenases/reductases family signature. 216591025462 classical (c) SDRs; Region: SDR_c; cd05233 216591025463 NAD(P) binding site [chemical binding]; other site 216591025464 active site 216591025465 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.4e-17 216591025466 PS00061 Short-chain dehydrogenases/reductases family signature. 216591025467 short chain dehydrogenase; Provisional; Region: PRK08303 216591025468 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591025469 NAD(P) binding site [chemical binding]; other site 216591025470 active site 216591025471 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.4e-11 216591025472 SnoaL-like domain; Region: SnoaL_4; pfam13577 216591025473 SnoaL-like domain; Region: SnoaL_3; pfam13474 216591025474 SnoaL-like domain; Region: SnoaL_4; pfam13577 216591025475 EthD domain; Region: EthD; pfam07110 216591025476 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 216591025477 tetramer interface [polypeptide binding]; other site 216591025478 active site 216591025479 Mg2+/Mn2+ binding site [ion binding]; other site 216591025480 isocitrate lyase; Region: PLN02892 216591025481 HMMPfam hit to PF00463, Isocitrate lyase family, score 2e-17 216591025482 YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function. The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336 216591025483 putative deacylase active site [active] 216591025484 HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associated do, score 8.5e-31 216591025485 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964 216591025486 YheO-like PAS domain; Region: PAS_6; pfam08348 216591025487 HTH domain; Region: HTH_22; pfam13309 216591025488 HMMPfam hit to PF08348, YheO-like protein, score 5.1e-56 216591025489 Predicted helix-turn-helix motif with score 1102.000, SD 2.94 at aa 191-212, sequence RAMEIVSQHLGVSRATVYNDAK 216591025490 Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171 216591025491 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 216591025492 tetramer interface [polypeptide binding]; other site 216591025493 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591025494 catalytic residue [active] 216591025495 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 4.4e-87 216591025496 hypothetical protein; Provisional; Region: PRK06194 216591025497 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591025498 NAD(P) binding site [chemical binding]; other site 216591025499 active site 216591025500 HMMPfam hit to PF00106, short chain dehydrogenase, score 7.3e-29 216591025501 Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206 216591025502 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591025503 N-terminal plug; other site 216591025504 ligand-binding site [chemical binding]; other site 216591025505 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 4.7e-26 216591025506 HMMPfam hit to PF00593, TonB dependent receptor, score 1.3e-28 216591025507 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591025508 WHG domain; Region: WHG; pfam13305 216591025509 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 216591025510 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 216591025511 HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 2e-60 216591025512 LysE type translocator; Region: LysE; cl00565 216591025513 HMMPfam hit to PF01810, LysE type translocator, score 1.2e-23 216591025514 5 probable transmembrane helices predicted for BCAM1596 by TMHMM2.0 at aa 7-29, 49-83, 113-135, 145-167 and 180-202 216591025515 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025516 helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344 216591025517 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591025518 putative DNA binding site [nucleotide binding]; other site 216591025519 putative Zn2+ binding site [ion binding]; other site 216591025520 AsnC family; Region: AsnC_trans_reg; pfam01037 216591025521 HMMPfam hit to PF01047, MarR family, score 0.0044 216591025522 Predicted helix-turn-helix motif with score 1546.000, SD 4.45 at aa 18-39, sequence ISYTELARQVHLSVPAVTERVK 216591025523 HMMPfam hit to PF01037, AsnC family, score 1.4e-22 216591025524 HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 8.5e-06 216591025525 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025526 Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604 216591025527 1 probable transmembrane helix predicted for BCAM1600 by TMHMM2.0 at aa 7-24 216591025528 Predicted metal-binding integral membrane protein (DUF2182); Region: DUF2182; pfam09948 216591025529 6 probable transmembrane helices predicted for BCAM1601 by TMHMM2.0 at aa 13-35, 68-90, 111-133, 148-167, 213-235 and 245-262 216591025530 Protein of unknown function (DUF1326); Region: DUF1326; cl02375 216591025531 HMMPfam hit to PF07040, Protein of unknown function (DUF1326), score 4e-93 216591025532 3 probable transmembrane helices predicted for BCAM1603 by TMHMM2.0 at aa 2-24, 34-56 and 69-91 216591025533 2 probable transmembrane helices predicted for BCAM1604 by TMHMM2.0 at aa 7-29 and 52-74 216591025534 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025535 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663 216591025536 paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745 216591025537 putative trimer interface [polypeptide binding]; other site 216591025538 putative metal binding site [ion binding]; other site 216591025539 PS00697 ATP-dependent DNA ligase AMP-binding site. 216591025540 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.015 216591025541 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 10 216591025542 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1.2e+02 216591025543 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.038 216591025544 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715 216591025545 Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766 216591025546 PS00696 Electron transfer flavoprotein alpha-subunit signature. 216591025547 HMMPfam hit to PF00766, Electron transfer flavoprotein FAD-binding, score 1.4e-54 216591025548 HMMPfam hit to PF01012, Electron transfer flavoprotein domain, score 2.8e-40 216591025549 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714 216591025550 Ligand binding site [chemical binding]; other site 216591025551 Electron transfer flavoprotein domain; Region: ETF; pfam01012 216591025552 HMMPfam hit to PF01012, Electron transfer flavoprotein domain, score 1.9e-69 216591025553 PS01065 Electron transfer flavoprotein beta-subunit signature. 216591025554 short chain dehydrogenase; Provisional; Region: PRK06114 216591025555 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591025556 NAD(P) binding site [chemical binding]; other site 216591025557 active site 216591025558 HMMPfam hit to PF00106, short chain dehydrogenase, score 8.4e-35 216591025559 methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657 216591025560 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343 216591025561 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.6e-27 216591025562 short chain dehydrogenase; Provisional; Region: PRK07856 216591025563 classical (c) SDRs; Region: SDR_c; cd05233 216591025564 NAD(P) binding site [chemical binding]; other site 216591025565 active site 216591025566 PS00017 ATP/GTP-binding site motif A (P-loop). 216591025567 HMMPfam hit to PF00106, short chain dehydrogenase, score 8.6e-27 216591025568 Protein of unknown function (DUF1302); Region: DUF1302; pfam06980 216591025569 HMMPfam hit to PF06980, Protein of unknown function (DUF1302), score 5.8e-55 216591025570 Protein of unknown function (DUF1329); Region: DUF1329; pfam07044 216591025571 HMMPfam hit to PF07044, Protein of unknown function (DUF1329), score 7.3e-106 216591025572 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 216591025573 HMMPfam hit to PF01689, Hydratase/decarboxylase, score 3e-109 216591025574 acetaldehyde dehydrogenase; Validated; Region: PRK08300 216591025575 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 216591025576 Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290 216591025577 HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindin, score 2.1e-23 216591025578 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195 216591025579 4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943 216591025580 active site 216591025581 catalytic residues [active] 216591025582 metal binding site [ion binding]; metal-binding site 216591025583 DmpG-like communication domain; Region: DmpG_comm; pfam07836 216591025584 HMMPfam hit to PF00682, HMGL-like, score 5.4e-97 216591025585 HMMPfam hit to PF07836, DmpG-like communication domain, score 3.5e-41 216591025586 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591025587 putative substrate translocation pore; other site 216591025588 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591025589 13 probable transmembrane helices predicted for BCAM1616 by TMHMM2.0 at aa 20-42, 49-71, 86-108, 115-137, 147-169, 176-195, 210-229, 234-253, 273-295, 308-330, 370-392, 404-426 and 436-455 216591025590 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.1e-51 216591025591 PS00216 Sugar transport proteins signature 1. 216591025592 S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451 216591025593 rRNA binding site [nucleotide binding]; other site 216591025594 predicted 30S ribosome binding site; other site 216591025595 HMMPfam hit to PF00575, S1 RNA binding domain, score 0.00018 216591025596 HMMPfam hit to PF01176, Translation initiation factor 1A / IF-1, score 6.5e-27 216591025597 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 216591025598 DNA-binding site [nucleotide binding]; DNA binding site 216591025599 RNA-binding motif; other site 216591025600 HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 6e-36 216591025601 PS00352 'Cold-shock' DNA-binding domain signature. 216591025602 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 216591025603 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938 216591025604 iron-sulfur cluster [ion binding]; other site 216591025605 [2Fe-2S] cluster binding site [ion binding]; other site 216591025606 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 8.3e-20 216591025607 Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033 216591025608 12 probable transmembrane helices predicted for BCAM1621 by TMHMM2.0 at aa 33-52, 239-261, 270-292, 297-319, 340-359, 369-391, 421-443, 627-649, 656-678, 682-704, 730-749 and 764-786 216591025609 Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447 216591025610 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 15 216591025611 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.5 216591025612 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 1.2 216591025613 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 3.7 216591025614 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 11 216591025615 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 11 216591025616 1 probable transmembrane helix predicted for BCAM1622 by TMHMM2.0 at aa 5-22 216591025617 acetyl-CoA acetyltransferase; Provisional; Region: PRK07108 216591025618 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 216591025619 dimer interface [polypeptide binding]; other site 216591025620 active site 216591025621 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 2.2e-56 216591025622 PS00099 Thiolases active site. 216591025623 PS00737 Thiolases signature 2. 216591025624 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 7.2e-78 216591025625 NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their...; Region: NodN; cd03450 216591025626 putative active site [active] 216591025627 putative catalytic site [active] 216591025628 HMMPfam hit to PF01575, MaoC like domain, score 6.4e-20 216591025629 short chain dehydrogenase; Provisional; Region: PRK07831 216591025630 classical (c) SDRs; Region: SDR_c; cd05233 216591025631 NAD(P) binding site [chemical binding]; other site 216591025632 active site 216591025633 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.1e-25 216591025634 PS00061 Short-chain dehydrogenases/reductases family signature. 216591025635 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591025636 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591025637 active site 216591025638 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 2.1e-20 216591025639 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 4.8e-25 216591025640 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591025641 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591025642 active site 216591025643 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 2.3e-25 216591025644 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 6.6e-06 216591025645 short chain dehydrogenase; Provisional; Region: PRK07791 216591025646 (3R)-hydroxyacyl-CoA dehydrogenase-like, classical(c)-like SDRs; Region: hydroxyacyl-CoA-like_DH_SDR_c-like; cd05353 216591025647 homodimer interface [polypeptide binding]; other site 216591025648 NAD binding site [chemical binding]; other site 216591025649 active site 216591025650 HMMPfam hit to PF00106, short chain dehydrogenase, score 9.2e-34 216591025651 PS00061 Short-chain dehydrogenases/reductases family signature. 216591025652 acetyl-CoA acetyltransferase; Provisional; Region: PRK07801 216591025653 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 216591025654 dimer interface [polypeptide binding]; other site 216591025655 active site 216591025656 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 1.1e-55 216591025657 PS00737 Thiolases signature 2. 216591025658 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 4.6e-56 216591025659 pimeloyl-CoA dehydrogenase, small subunit; Region: pimD_small; TIGR03203 216591025660 Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771 216591025661 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591025662 active site 216591025663 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 2.4e-22 216591025664 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 0.00091 216591025665 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591025666 Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26; Region: ACAD_fadE6_17_26; cd01152 216591025667 FAD binding site [chemical binding]; other site 216591025668 substrate binding site [chemical binding]; other site 216591025669 catalytic base [active] 216591025670 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 4.9e-15 216591025671 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 2.1e-21 216591025672 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591025673 enoyl-CoA hydratase; Provisional; Region: PRK06495 216591025674 substrate binding site [chemical binding]; other site 216591025675 oxyanion hole (OAH) forming residues; other site 216591025676 trimer interface [polypeptide binding]; other site 216591025677 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 1.4e-36 216591025678 1 probable transmembrane helix predicted for BCAM1632 by TMHMM2.0 at aa 107-129 216591025679 putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151 216591025680 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 216591025681 FMN binding site [chemical binding]; other site 216591025682 substrate binding site [chemical binding]; other site 216591025683 putative catalytic residue [active] 216591025684 HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 1e-85 216591025685 PS00211 ABC transporters family signature. 216591025686 enoyl-CoA hydratase; Provisional; Region: PRK08290 216591025687 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591025688 substrate binding site [chemical binding]; other site 216591025689 oxyanion hole (OAH) forming residues; other site 216591025690 trimer interface [polypeptide binding]; other site 216591025691 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 4.7e-28 216591025692 Coenzyme A transferase; Region: CoA_trans; cl17247 216591025693 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788 216591025694 HMMPfam hit to PF01144, Coenzyme A transferase, score 3.5e-35 216591025695 2,3-dihydroxybiphenyl 1,2-dioxygenase; Region: 23dbph12diox; TIGR03213 216591025696 N-terminal domain of 2,3-dihydroxybiphenyl 1,2-dioxygenase (BphC, EC 1.13.11.39) 1 from Rhodococcus globerulus P6 (BphC1-RGP6) and similar proteins; Region: BphC1-RGP6_N_like; cd07252 216591025697 C-terminal domain of 2,3-dihydroxybiphenyl 1,2-dioxygenase (BphC, EC 1.13.11.39) 1 from Rhodococcus globerulus P6 (BphC1-RGP6) and similar proteins; Region: BphC1-RGP6_C_like; cd07237 216591025698 active site 216591025699 Fe binding site [ion binding]; other site 216591025700 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 1.2e-21 216591025701 PS00082 Extradiol ring-cleavage dioxygenases signature. 216591025702 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 0.0006 216591025703 PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881 216591025704 oligomeric interface; other site 216591025705 putative active site [active] 216591025706 homodimer interface [polypeptide binding]; other site 216591025707 HMMPfam hit to PF01850, PIN domain, score 1.6e-13 216591025708 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 216591025709 9 probable transmembrane helices predicted for BCAM1640 by TMHMM2.0 at aa 20-42, 63-85, 95-112, 133-152, 193-215, 222-244, 290-312, 319-341 and 356-378 216591025710 HMMPfam hit to PF01757, Acyltransferase family, score 1.5e-21 216591025711 PS01047 Heavy-metal-associated domain. 216591025712 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028 216591025713 classical (c) SDRs; Region: SDR_c; cd05233 216591025714 NAD(P) binding site [chemical binding]; other site 216591025715 active site 216591025716 HMMPfam hit to PF00106, short chain dehydrogenase, score 4.4e-11 216591025717 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07656 216591025718 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591025719 Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917 216591025720 acyl-activating enzyme (AAE) consensus motif; other site 216591025721 acyl-activating enzyme (AAE) consensus motif; other site 216591025722 putative AMP binding site [chemical binding]; other site 216591025723 putative active site [active] 216591025724 putative CoA binding site [chemical binding]; other site 216591025725 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.5e-119 216591025726 PS00455 Putative AMP-binding domain signature. 216591025727 phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160 216591025728 NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214 216591025729 FAD binding pocket [chemical binding]; other site 216591025730 FAD binding motif [chemical binding]; other site 216591025731 phosphate binding motif [ion binding]; other site 216591025732 beta-alpha-beta structure motif; other site 216591025733 NAD(p) ribose binding residues [chemical binding]; other site 216591025734 NAD binding pocket [chemical binding]; other site 216591025735 NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site 216591025736 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591025737 catalytic loop [active] 216591025738 iron binding site [ion binding]; other site 216591025739 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 2.4e-22 216591025740 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591025741 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 5.4e-14 216591025742 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 1.1e-16 216591025743 Flavin reductase like domain; Region: Flavin_Reduct; smart00903 216591025744 HMMPfam hit to PF01613, Flavin reductase like domain, score 2e-31 216591025745 3-ketosteroid-delta-1-dehydrogenase; Reviewed; Region: PRK07843 216591025746 putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834 216591025747 HMMPfam hit to PF00890, FAD binding domain, score 2.8e-116 216591025748 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00036 216591025749 Naphthocyclinone hydroxylase; Region: NcnH; cd01159 216591025750 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591025751 Flavin binding site [chemical binding]; other site 216591025752 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 5.5e-29 216591025753 probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858 216591025754 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141 216591025755 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 1.6e-21 216591025756 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591025757 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587 216591025758 active site 216591025759 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 0.00016 216591025760 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591025761 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591025762 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591025763 dimerization interface [polypeptide binding]; other site 216591025764 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.6e-26 216591025765 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.4e-15 216591025766 PS00044 Bacterial regulatory proteins, lysR family signature. 216591025767 Predicted helix-turn-helix motif with score 1906.000, SD 5.68 at aa 17-38, sequence RSFTEAGRQLGLNQSSVSEHIR 216591025768 putative transporter; Provisional; Region: PRK10504 216591025769 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591025770 putative substrate translocation pore; other site 216591025771 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591025772 14 probable transmembrane helices predicted for BCAM1651 by TMHMM2.0 at aa 9-31, 46-68, 75-97, 101-123, 130-152, 162-184, 197-214, 224-241, 262-284, 289-311, 324-346, 356-378, 399-418 and 422-444 216591025773 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.1e-56 216591025774 Domain of unknown function (DUF4377); Region: DUF4377; pfam14302 216591025775 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025776 helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421 216591025777 DNA binding residues [nucleotide binding] 216591025778 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 4.1e-05 216591025779 HMMPfam hit to PF04967, HTH DNA binding domain, score 0.0016 216591025780 Predicted helix-turn-helix motif with score 1489.000, SD 4.26 at aa 361-382, sequence QTLEEAADELAISKNTARSHLR 216591025781 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 216591025782 classical (c) SDRs; Region: SDR_c; cd05233 216591025783 NAD(P) binding site [chemical binding]; other site 216591025784 active site 216591025785 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.3e-30 216591025786 PS00061 Short-chain dehydrogenases/reductases family signature. 216591025787 Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973 216591025788 INT_SG1, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 1, C-terminal catalytic domain. The CD contains mainly predicted integrase/recombinase and site-specific XerD recombinases. The members of this CD are found predominantly in...; Region: INT_SG1_C; cd01183 216591025789 Int/Topo IB signature motif; other site 216591025790 HMMPfam hit to PF00589, Phage integrase family, score 4.7e-08 216591025791 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025792 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102 216591025793 HMMPfam hit to PF07394, Protein of unknown function (DUF1501), score 7.1e-31 216591025794 Protein of unknown function (DUF1800); Region: DUF1800; pfam08811 216591025795 Heavy-metal resistance; Region: Metal_resist; pfam13801 216591025796 1 probable transmembrane helix predicted for BCAM1659 by TMHMM2.0 at aa 10-32 216591025797 1 probable transmembrane helix predicted for BCAM1660 by TMHMM2.0 at aa 85-107 216591025798 RNA polymerase sigma factor; Reviewed; Region: PRK05602 216591025799 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591025800 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591025801 HMMPfam hit to PF04545, Sigma-70, region, score 3.3e-14 216591025802 HMMPfam hit to PF08281, Sigma-70, region, score 1.3e-14 216591025803 HMMPfam hit to PF04542, Sigma-70 region, score 1.8e-22 216591025804 PS01063 Sigma-70 factors ECF subfamily signature. 216591025805 1 probable transmembrane helix predicted for BCAM1662 by TMHMM2.0 at aa 7-29 216591025806 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 216591025807 active site 216591025808 metal binding site [ion binding]; metal-binding site 216591025809 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 2.5e-10 216591025810 Probable gene remnant. Similar to an internal region of Agrobacterium tumefaciens (strain c58/atcc 33970) aldehyde dehydrogenase Dhal UniProt:Q8U8X9 (EMBL:AE009326 (505 aa) fasta scores: E()=1.8e-08, 67.347% id in 49 aa 216591025811 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591025812 aromatic amino acid exporter; Provisional; Region: PRK11689 216591025813 10 probable transmembrane helices predicted for BCAM1664 by TMHMM2.0 at aa 7-29, 34-56, 65-87, 92-114, 121-140, 160-177, 190-212, 216-238, 245-267 and 271-290 216591025814 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591025815 HMMPfam hit to PF01810, LysE type translocator, score 1.2e-20 216591025816 5 probable transmembrane helices predicted for BCAM1665 by TMHMM2.0 at aa 6-28, 41-63, 73-92, 113-135 and 158-180 216591025817 DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242 216591025818 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591025819 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591025820 dimerization interface [polypeptide binding]; other site 216591025821 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.2e-32 216591025822 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.2e-15 216591025823 PS00044 Bacterial regulatory proteins, lysR family signature. 216591025824 Predicted helix-turn-helix motif with score 1649.000, SD 4.80 at aa 16-37, sequence GSLTAAADRLSRSQSAISHALT 216591025825 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 216591025826 8 probable transmembrane helices predicted for BCAM1667 by TMHMM2.0 at aa 10-32, 39-58, 90-112, 119-137, 152-174, 187-209, 213-230 and 242-259 216591025827 HMMPfam hit to PF01925, Domain of unknown function DUF81, score 1.7e-10 216591025828 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591025829 1 probable transmembrane helix predicted for BCAM1669 by TMHMM2.0 at aa 4-22 216591025830 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591025831 dimerization interface [polypeptide binding]; other site 216591025832 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591025833 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591025834 metal binding site [ion binding]; metal-binding site 216591025835 active site 216591025836 I-site; other site 216591025837 HMMPfam hit to PF00990, GGDEF domain, score 1.2e-59 216591025838 HMMPfam hit to PF00672, HAMP domain, score 3.4e-12 216591025839 2 probable transmembrane helices predicted for BCAM1670 by TMHMM2.0 at aa 10-32 and 323-345 216591025840 Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416 216591025841 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 216591025842 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591025843 DNA-binding site [nucleotide binding]; DNA binding site 216591025844 Transcriptional regulators [Transcription]; Region: FadR; COG2186 216591025845 FCD domain; Region: FCD; pfam07729 216591025846 HMMPfam hit to PF07729, FCD domain, score 2e-30 216591025847 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 5.8e-20 216591025848 Predicted helix-turn-helix motif with score 1243.000, SD 3.42 at aa 43-64, sequence PSERSLADQFGVSRTQVREAII 216591025849 mannonate dehydratase; Provisional; Region: PRK03906 216591025850 mannonate dehydratase; Region: uxuA; TIGR00695 216591025851 HMMPfam hit to PF03786, D-mannonate dehydratase (UxuA), score 6.3e-213 216591025852 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 0.0021 216591025853 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591025854 D-galactonate transporter; Region: 2A0114; TIGR00893 216591025855 putative substrate translocation pore; other site 216591025856 9 probable transmembrane helices predicted for BCAM1673 by TMHMM2.0 at aa 7-29, 44-66, 73-95, 160-182, 227-249, 264-286, 327-349, 364-386 and 391-413 216591025857 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.4e-56 216591025858 PS00211 ABC transporters family signature. 216591025859 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591025860 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591025861 DNA-binding site [nucleotide binding]; DNA binding site 216591025862 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591025863 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591025864 homodimer interface [polypeptide binding]; other site 216591025865 catalytic residue [active] 216591025866 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 8e-14 216591025867 Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 27-48, sequence PSLRQIIAQHGVSQSTVFRAYY 216591025868 HMMPfam hit to PF00155, Aminotransferase class I and II, score 2.7e-14 216591025869 Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155 216591025870 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 216591025871 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 216591025872 HMMPfam hit to PF03460, Nitrite/Sulfite reductase ferredoxin-lik, score 1.1e-09 216591025873 HMMPfam hit to PF01077, Nitrite and sulphite reductase 4Fe-4S do, score 5.3e-48 216591025874 HMMPfam hit to PF03460, Nitrite/Sulfite reductase ferredoxin-lik, score 3.8e-11 216591025875 HMMPfam hit to PF01077, Nitrite and sulphite reductase 4Fe-4S do, score 3.5e-07 216591025876 Bacterial protein of unknown function (DUF934); Region: DUF934; pfam06073 216591025877 HMMPfam hit to PF06073, Bacterial protein of unknown function (DUF93, score 5.5e-11 216591025878 Type IV secretory pathway, VirJ component [Intracellular trafficking and secretion]; Region: VirJ; COG3946 216591025879 Bacterial virulence protein (VirJ); Region: VirJ; pfam06057 216591025880 HMMPfam hit to PF06057, Bacterial virulence protein (VirJ), score 2.5e-106 216591025881 PS00120 Lipases, serine active site. 216591025882 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025883 Predicted integral membrane protein [Function unknown]; Region: COG0392 216591025884 Uncharacterized conserved protein [Function unknown]; Region: COG2898 216591025885 Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924 216591025886 HMMPfam hit to PF04331, Family of unknown function (DUF472), score 6.7e-26 216591025887 HMMPfam hit to PF04330, Family of unknown function (DUF471), score 2.8e-15 216591025888 HMMPfam hit to PF04329, Family of unknown function (DUF470), score 4.1e-51 216591025889 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591025890 14 probable transmembrane helices predicted for BCAM1679 by TMHMM2.0 at aa 28-45, 66-88, 103-125, 146-168, 183-205, 226-248, 258-280, 301-323, 343-365, 378-400, 410-429, 431-450, 465-487 and 508-530 216591025891 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591025892 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591025893 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474 216591025894 putative effector binding pocket; other site 216591025895 putative dimerization interface [polypeptide binding]; other site 216591025896 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.3e-42 216591025897 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.3e-20 216591025898 PS00044 Bacterial regulatory proteins, lysR family signature. 216591025899 Predicted helix-turn-helix motif with score 1197.000, SD 3.26 at aa 20-41, sequence GNFTRAAAALGLTPAAVSLSIG 216591025900 Domain of unknown function (DUF336); Region: DUF336; pfam03928 216591025901 short chain dehydrogenase; Provisional; Region: PRK09291 216591025902 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374 216591025903 NADP binding site [chemical binding]; other site 216591025904 active site 216591025905 steroid binding site; other site 216591025906 HMMPfam hit to PF03928, Domain of unknown function (DUF336), score 4.2e-38 216591025907 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.2e-23 216591025908 HMMPfam hit to PF07993, Male sterility protein, score 0.0046 216591025909 PS00061 Short-chain dehydrogenases/reductases family signature. 216591025910 Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754 216591025911 formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591 216591025912 [4Fe-4S] binding site [ion binding]; other site 216591025913 molybdopterin cofactor binding site; other site 216591025914 Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791 216591025915 molybdopterin cofactor binding site; other site 216591025916 Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369 216591025917 Flavodoxin; Region: Flavodoxin_1; pfam00258 216591025918 Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199 216591025919 FAD binding pocket [chemical binding]; other site 216591025920 FAD binding motif [chemical binding]; other site 216591025921 catalytic residues [active] 216591025922 NAD binding pocket [chemical binding]; other site 216591025923 phosphate binding motif [ion binding]; other site 216591025924 beta-alpha-beta structure motif; other site 216591025925 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 2.2e-28 216591025926 HMMPfam hit to PF00667, FAD binding domain, score 5.6e-36 216591025927 HMMPfam hit to PF00258, Flavodoxin, score 2.4e-30 216591025928 HMMPfam hit to PF01568, Molydopterin dinucleotide binding dom, score 5.4e-47 216591025929 PS00030 Eukaryotic putative RNA-binding region RNP-1 signature. 216591025930 HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 1.5e-87 216591025931 HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 do, score 9.3e-22 216591025932 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 216591025933 Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529 216591025934 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 0.0086 216591025935 nitrite reductase subunit NirD; Provisional; Region: PRK14989 216591025936 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591025937 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 216591025938 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 216591025939 HMMPfam hit to PF01077, Nitrite and sulphite reductase 4Fe-4S do, score 2e-43 216591025940 PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 216591025941 HMMPfam hit to PF03460, Nitrite/Sulfite reductase ferredoxin-lik, score 3.4e-24 216591025942 HMMPfam hit to PF04324, BFD-like [2Fe-2S] binding domain, score 7e-23 216591025943 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoredu, score 1.4e-43 216591025944 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoredu, score 2.5e-21 216591025945 nitrite extrusion protein (nitrite facilitator); Region: 2A0108; TIGR00886 216591025946 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591025947 putative substrate translocation pore; other site 216591025948 12 probable transmembrane helices predicted for BCAM1686 by TMHMM2.0 at aa 21-43, 53-75, 87-104, 108-127, 148-170, 180-199, 244-266, 276-298, 311-333, 337-359, 366-388 and 398-420 216591025949 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.1e-24 216591025950 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025951 Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642 216591025952 active site 216591025953 SAM binding site [chemical binding]; other site 216591025954 homodimer interface [polypeptide binding]; other site 216591025955 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 7.7e-70 216591025956 PS00839 Uroporphyrin-III C-methyltransferase signature 1. 216591025957 Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707 216591025958 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591025959 active site 216591025960 phosphorylation site [posttranslational modification] 216591025961 intermolecular recognition site; other site 216591025962 dimerization interface [polypeptide binding]; other site 216591025963 ANTAR domain; Region: ANTAR; pfam03861 216591025964 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.6e-05 216591025965 HMMPfam hit to PF03861, ANTAR domain, score 4.3e-17 216591025966 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 216591025967 NMT1-like family; Region: NMT1_2; pfam13379 216591025968 Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_1; cd10033 216591025969 putative uracil binding site [chemical binding]; other site 216591025970 putative active site [active] 216591025971 HMMPfam hit to PF03167, Uracil DNA glycosylase superfamily, score 1.1e-06 216591025972 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591025973 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591025974 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.8e-05 216591025975 Predicted helix-turn-helix motif with score 1220.000, SD 3.34 at aa 213-234, sequence LTLAATAEAAFLSPNYLAHLVR 216591025976 PS00041 Bacterial regulatory proteins, araC family signature. 216591025977 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3e-12 216591025978 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 216591025979 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 216591025980 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 8.9e-57 216591025981 Domain of unknown function (DUF4303); Region: DUF4303; pfam14136 216591025982 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591025983 putative substrate translocation pore; other site 216591025984 11 probable transmembrane helices predicted for BCAM1694 by TMHMM2.0 at aa 15-37, 50-69, 84-106, 137-159, 163-185, 214-236, 251-270, 282-304, 309-331, 344-366 and 371-393 216591025985 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.3e-40 216591025986 PS00216 Sugar transport proteins signature 1. 216591025987 periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037 216591025988 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 216591025989 PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117 216591025990 protein binding site [polypeptide binding]; other site 216591025991 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 216591025992 protein binding site [polypeptide binding]; other site 216591025993 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 0.0092 216591025994 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 5.5e-05 216591025995 HMMPfam hit to PF00089, Trypsin, score 2.4e-08 216591025996 1 probable transmembrane helix predicted for BCAM1695 by TMHMM2.0 at aa 13-35 216591025997 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591025998 CAAX protease self-immunity; Region: Abi; pfam02517 216591025999 7 probable transmembrane helices predicted for BCAM1697 by TMHMM2.0 at aa 13-35, 47-66, 86-108, 128-147, 175-197, 210-232 and 242-261 216591026000 PS00041 Bacterial regulatory proteins, araC family signature. 216591026001 HMMPfam hit to PF02517, CAAX amino terminal protease family, score 1.9e-16 216591026002 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591026003 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591026004 DNA-binding site [nucleotide binding]; DNA binding site 216591026005 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591026006 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591026007 homodimer interface [polypeptide binding]; other site 216591026008 catalytic residue [active] 216591026009 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.4e-09 216591026010 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 2.3e-11 216591026011 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 216591026012 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591026013 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 216591026014 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591026015 Coenzyme A binding pocket [chemical binding]; other site 216591026016 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 5.4e-05 216591026017 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 7.9e-16 216591026018 Domain of unknown function (DUF3331); Region: DUF3331; pfam11811 216591026019 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591026020 putative substrate translocation pore; other site 216591026021 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591026022 12 probable transmembrane helices predicted for BCAM1702 by TMHMM2.0 at aa 30-52, 67-89, 96-118, 122-144, 156-178, 182-204, 230-249, 264-286, 293-315, 319-341, 354-376 and 386-405 216591026023 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7e-36 216591026024 Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508 216591026025 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.7e-15 216591026026 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 216591026027 (2R,3R)-2,3-butanediol dehydrogenase; Region: butanediol_DH_like; cd08233 216591026028 putative NAD(P) binding site [chemical binding]; other site 216591026029 catalytic Zn binding site [ion binding]; other site 216591026030 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 8.4e-47 216591026031 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591026032 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.4e-45 216591026033 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 216591026034 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591026035 dimer interface [polypeptide binding]; other site 216591026036 phosphorylation site [posttranslational modification] 216591026037 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591026038 ATP binding site [chemical binding]; other site 216591026039 Mg2+ binding site [ion binding]; other site 216591026040 G-X-G motif; other site 216591026041 1 probable transmembrane helix predicted for BCAM1705 by TMHMM2.0 at aa 77-99 216591026042 PS00215 Mitochondrial energy transfer proteins signature. 216591026043 PS00216 Sugar transport proteins signature 1. 216591026044 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.0016 216591026045 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3.5e-36 216591026046 6 probable transmembrane helices predicted for BCAM1706 by TMHMM2.0 at aa 12-29, 39-56, 63-82, 87-109, 150-167 and 177-199 216591026047 9 probable transmembrane helices predicted for BCAM1707 by TMHMM2.0 at aa 2-24, 44-66, 73-95, 115-137, 150-172, 182-204, 211-233, 237-256 and 261-283 216591026048 HMMPfam hit to PF02517, CAAX amino terminal protease family, score 4.9e-08 216591026049 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591026050 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 216591026051 active site 216591026052 catalytic tetrad [active] 216591026053 HMMPfam hit to PF00248, Aldo/keto reductase family, score 3e-74 216591026054 MarC family integral membrane protein; Region: MarC; cl00919 216591026055 HMMPfam hit to PF01914, MarC family integral membrane protein, score 2.8e-24 216591026056 5 probable transmembrane helices predicted for BCAM1709 by TMHMM2.0 at aa 25-47, 67-89, 136-158, 167-189 and 209-231 216591026057 enoyl-CoA hydratase; Provisional; Region: PRK05995 216591026058 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591026059 substrate binding site [chemical binding]; other site 216591026060 oxyanion hole (OAH) forming residues; other site 216591026061 trimer interface [polypeptide binding]; other site 216591026062 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 2.7e-45 216591026063 Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913 216591026064 phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155 216591026065 active site 216591026066 AMP binding site [chemical binding]; other site 216591026067 homodimer interface [polypeptide binding]; other site 216591026068 acyl-activating enzyme (AAE) consensus motif; other site 216591026069 CoA binding site [chemical binding]; other site 216591026070 3-hydroxy-acyl-CoA dehydrogenase; Validated; Region: PRK08268 216591026071 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 216591026072 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 216591026073 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 216591026074 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-term, score 4.5e-14 216591026075 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-term, score 1.2e-45 216591026076 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD bi, score 3.1e-74 216591026077 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 0.00063 216591026078 1 probable transmembrane helix predicted for BCAM1712 by TMHMM2.0 at aa 13-35 216591026079 Ca2+/H+ antiporter [Inorganic ion transport and metabolism]; Region: ChaA; COG0387 216591026080 11 probable transmembrane helices predicted for BCAM1713 by TMHMM2.0 at aa 13-30, 34-56, 68-90, 100-122, 134-156, 166-185, 215-237, 252-274, 287-309, 313-335 and 342-361 216591026081 HMMPfam hit to PF01699, Sodium/calcium exchanger protein, score 5.7e-22 216591026082 Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618 216591026083 2-pyrone-4,6-dicarboxylic acid (PDC) hydrolase hydrolyzes PDC to yield 4-oxalomesaconic acid (OMA) or its tautomer, 4-carboxy-2-hydroxymuconic acid (CHM). This reaction is part of the protocatechuate (PCA) 4,5-cleavage pathway. PCA is one of the most...; Region: PDC_hydrolase; cd01311 216591026084 active site 216591026085 HMMPfam hit to PF04909, Amidohydrolase, score 2.3e-50 216591026086 Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_8; cd12167 216591026087 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 216591026088 putative ligand binding site [chemical binding]; other site 216591026089 putative NAD binding site [chemical binding]; other site 216591026090 catalytic site [active] 216591026091 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 2.3e-10 216591026092 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 5.9e-62 216591026093 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591026094 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591026095 DNA binding site [nucleotide binding] 216591026096 domain linker motif; other site 216591026097 Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_10; cd06292 216591026098 putative dimerization interface [polypeptide binding]; other site 216591026099 putative ligand binding site [chemical binding]; other site 216591026100 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 8.8e-08 216591026101 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 6.2e-08 216591026102 Predicted helix-turn-helix motif with score 1860.000, SD 5.52 at aa 6-27, sequence STIQDVARHAAVSVSTVSNVLN 216591026103 PS00356 Bacterial regulatory proteins, lacI family signature. 216591026104 TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090 216591026105 DctM-like transporters; Region: DctM; pfam06808 216591026106 TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593 216591026107 17 probable transmembrane helices predicted for BCAM1717 by TMHMM2.0 at aa 32-54, 64-86, 107-126, 146-168, 175-197, 212-234, 255-277, 287-309, 338-360, 366-388, 408-430, 434-456, 468-490, 510-532, 537-554, 559-581 and 602-624 216591026108 HMMPfam hit to PF06808, DctM-like transporters, score 2.7e-109 216591026109 HMMPfam hit to PF04290, Tripartite ATP-independent periplasmic trans, score 1.8e-23 216591026110 TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638 216591026111 Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; cl15441 216591026112 HMMPfam hit to PF03480, Bacterial extracellular solute-binding prot, score 4.8e-50 216591026113 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 216591026114 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026115 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591026116 dimerization interface [polypeptide binding]; other site 216591026117 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-38 216591026118 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2e-19 216591026119 PS00044 Bacterial regulatory proteins, lysR family signature. 216591026120 Predicted helix-turn-helix motif with score 1469.000, SD 4.19 at aa 17-38, sequence LHFGRAARRLFMTQPPLSRQIQ 216591026121 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 216591026122 Hydroxy(phenyl)pyruvate Reductase, D-isomer-specific 2-hydroxyacid-related dehydrogenase; Region: HPPR; cd12156 216591026123 putative ligand binding site [chemical binding]; other site 216591026124 NAD binding site [chemical binding]; other site 216591026125 catalytic site [active] 216591026126 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 1.3e-24 216591026127 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 4e-63 216591026128 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591026129 D-galactonate transporter; Region: 2A0114; TIGR00893 216591026130 putative substrate translocation pore; other site 216591026131 HMMPfam hit to PF00083, Sugar (and other) transporter score 0.00019 216591026132 12 probable transmembrane helices predicted for BCAM1721 by TMHMM2.0 at aa 37-59, 74-96, 103-125, 129-151, 172-191, 201-220, 273-295, 310-332, 345-364, 369-391, 404-426 and 431-453 216591026133 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.8e-56 216591026134 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591026135 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026136 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591026137 putative effector binding pocket; other site 216591026138 dimerization interface [polypeptide binding]; other site 216591026139 HMMPfam hit to PF03466, LysR substrate binding domain, score 4e-41 216591026140 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.4e-14 216591026141 Predicted helix-turn-helix motif with score 1215.000, SD 3.33 at aa 17-38, sequence GSFTAVAKEIDATTAQVSRAVS 216591026142 CBS-domain-containing membrane protein [Signal transduction mechanisms]; Region: COG3448 216591026143 HPP family; Region: HPP; pfam04982 216591026144 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354 216591026145 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the HPP motif domain. These proteins are integral membrane proteins with four transmembrane spanning helices. The function of these proteins is...; Region: CBS_pair_HPP_assoc; cd04600 216591026146 HMMPfam hit to PF04982, HPP family, score 5.3e-45 216591026147 4 probable transmembrane helices predicted for BCAM1723 by TMHMM2.0 at aa 55-77, 84-106, 110-129 and 134-156 216591026148 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591026149 HMMPfam hit to PF00571, CBS domain pair, score 5.4e-34 216591026150 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591026151 MarR family; Region: MarR_2; pfam12802 216591026152 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591026153 HMMPfam hit to PF01047, MarR family, score 0.00028 216591026154 Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038 216591026155 CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400 216591026156 Cl- selectivity filter; other site 216591026157 Cl- binding residues [ion binding]; other site 216591026158 pore gating glutamate residue; other site 216591026159 dimer interface [polypeptide binding]; other site 216591026160 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with either the SpoIVFB domain (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) or the chloride channel protein EriC; Region: CBS_pair_SpoIVFB_EriC_assoc; cd04612 216591026161 11 probable transmembrane helices predicted for BCAM1725 by TMHMM2.0 at aa 21-43, 63-85, 118-140, 169-191, 198-217, 232-254, 267-286, 306-325, 332-354, 364-386 and 393-412 216591026162 HMMPfam hit to PF00654, Voltage gated chloride channel, score 4.6e-13 216591026163 HMMPfam hit to PF00571, CBS domain pair, score 1.9e-05 216591026164 Protein of unknown function (DUF1255); Region: DUF1255; pfam06865 216591026165 HMMPfam hit to PF06865, Protein of unknown function (DUF1255), score 5.4e-46 216591026166 PS00430 TonB-dependent receptor proteins signature 1. 216591026167 putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791 216591026168 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026169 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591026170 dimerization interface [polypeptide binding]; other site 216591026171 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.9e-29 216591026172 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.7e-21 216591026173 PS00044 Bacterial regulatory proteins, lysR family signature. 216591026174 Predicted helix-turn-helix motif with score 1745.000, SD 5.13 at aa 16-37, sequence GSIRAAARRLNVSPAALTKAVK 216591026175 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 216591026176 M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666 216591026177 metal binding site [ion binding]; metal-binding site 216591026178 putative dimer interface [polypeptide binding]; other site 216591026179 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 6e-68 216591026180 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 6.5e-08 216591026181 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591026182 HMMPfam hit to PF00083, Sugar (and other) transporter score 1.3e-07 216591026183 12 probable transmembrane helices predicted for BCAM1730 by TMHMM2.0 at aa 25-47, 62-84, 96-118, 128-150, 171-193, 198-215, 252-274, 284-306, 318-336, 346-368, 381-403 and 413-430 216591026184 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.4e-15 216591026185 PS00216 Sugar transport proteins signature 1. 216591026186 PS00217 Sugar transport proteins signature 2. 216591026187 Isochorismatase family; Region: Isochorismatase; pfam00857 216591026188 Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014 216591026189 catalytic triad [active] 216591026190 conserved cis-peptide bond; other site 216591026191 HMMPfam hit to PF00857, Isochorismatase family, score 1.4e-10 216591026192 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591026193 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591026194 trimer interface [polypeptide binding]; other site 216591026195 eyelet of channel; other site 216591026196 HMMPfam hit to PF00267, Gram-negative porin, score 0.00088 216591026197 1 probable transmembrane helix predicted for BCAM1732 by TMHMM2.0 at aa 5-27 216591026198 Predicted membrane protein [Function unknown]; Region: COG2259 216591026199 4 probable transmembrane helices predicted for BCAM1733 by TMHMM2.0 at aa 21-43, 53-75, 80-102 and 117-136 216591026200 HMMPfam hit to PF07681, DoxX, score 4.1e-34 216591026201 Cytochrome c; Region: Cytochrom_C; pfam00034 216591026202 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591026203 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591026204 Cytochrome c; Region: Cytochrom_C; pfam00034 216591026205 HMMPfam hit to PF00034, Cytochrome c, score 1.1e-05 216591026206 PS00190 Cytochrome c family heme-binding site signature. 216591026207 PS00190 Cytochrome c family heme-binding site signature. 216591026208 PS00190 Cytochrome c family heme-binding site signature. 216591026209 Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303 216591026210 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 216591026211 HMMPfam hit to PF00732, GMC oxidoreductase, score 4.6e-05 216591026212 1 probable transmembrane helix predicted for BCAM1735 by TMHMM2.0 at aa 12-29 216591026213 Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318 216591026214 Bacterial Ig-like domain; Region: Big_5; pfam13205 216591026215 MG2 domain; Region: A2M_N; pfam01835 216591026216 Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703 216591026217 Alpha-2-macroglobulin family; Region: A2M; pfam00207 216591026218 1 probable transmembrane helix predicted for BCAM1737 by TMHMM2.0 at aa 20-42 216591026219 HMMPfam hit to PF01835, Alpha-2-macroglobulin family N-terminal regi, score 5.1e-33 216591026220 PS00017 ATP/GTP-binding site motif A (P-loop). 216591026221 penicillin-binding protein 1C; Region: PBP_1c; TIGR02073 216591026222 Transglycosylase; Region: Transgly; pfam00912 216591026223 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 216591026224 Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832 216591026225 1 probable transmembrane helix predicted for BCAM1738 by TMHMM2.0 at aa 7-29 216591026226 HMMPfam hit to PF00912, Transglycosylase, score 1.9e-41 216591026227 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 9.5e-07 216591026228 1 probable transmembrane helix predicted for BCAM1739 by TMHMM2.0 at aa 84-106 216591026229 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591026230 drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710 216591026231 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591026232 putative substrate translocation pore; other site 216591026233 11 probable transmembrane helices predicted for BCAM1741 by TMHMM2.0 at aa 30-52, 67-89, 96-115, 121-143, 156-175, 180-202, 235-257, 267-285, 306-328, 353-375 and 382-404 216591026234 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.2e-45 216591026235 1 probable transmembrane helix predicted for BCAM1742 by TMHMM2.0 at aa 21-43 216591026236 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591026237 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591026238 substrate binding pocket [chemical binding]; other site 216591026239 membrane-bound complex binding site; other site 216591026240 hinge residues; other site 216591026241 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 6.9e-47 216591026242 1 probable transmembrane helix predicted for BCAM1743 by TMHMM2.0 at aa 7-29 216591026243 Peptidase S8 family domain, uncharacterized subfamily 13; Region: Peptidases_S8_13; cd07496 216591026244 active site 216591026245 catalytic triad [active] 216591026246 HMMPfam hit to PF00082, Subtilase family, score 3.3e-65 216591026247 PS00138 Serine proteases, subtilase family, serine active site. 216591026248 magnesium-transporting ATPase; Provisional; Region: PRK15122 216591026249 Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831 216591026250 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 216591026251 Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246 216591026252 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591026253 motif II; other site 216591026254 Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689 216591026255 HMMPfam hit to PF00690, Cation transporter/ATPase, N-terminus, score 5.9e-22 216591026256 8 probable transmembrane helices predicted for BCAM1745 by TMHMM2.0 at aa 95-117, 122-141, 307-329, 339-361, 789-811, 826-848, 860-882 and 897-919 216591026257 HMMPfam hit to PF00122, E1-E2 ATPase, score 8.7e-73 216591026258 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1e-20 216591026259 PS00154 E1-E2 ATPases phosphorylation site. 216591026260 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591026261 Predicted helix-turn-helix motif with score 1343.000, SD 3.76 at aa 33-54, sequence WSLPKIAKRAQLPMSTLRRVLT 216591026262 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 216591026263 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026264 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 216591026265 dimerization interface [polypeptide binding]; other site 216591026266 substrate binding pocket [chemical binding]; other site 216591026267 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.2e-32 216591026268 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.1e-22 216591026269 PS00044 Bacterial regulatory proteins, lysR family signature. 216591026270 Predicted helix-turn-helix motif with score 1694.000, SD 4.96 at aa 16-37, sequence CHFSRAADALHMSQPALSKQIG 216591026271 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872 216591026272 D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768 216591026273 1 probable transmembrane helix predicted for BCAM1748 by TMHMM2.0 at aa 13-32 216591026274 HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase, score 1.7e-37 216591026275 PS00294 Prenyl group binding site (CAAX box). 216591026276 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591026277 MarR family; Region: MarR; pfam01047 216591026278 HMMPfam hit to PF01047, MarR family, score 5e-14 216591026279 Isochorismatase family; Region: Isochorismatase; pfam00857 216591026280 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431 216591026281 catalytic triad [active] 216591026282 conserved cis-peptide bond; other site 216591026283 HMMPfam hit to PF00857, Isochorismatase family, score 4.3e-41 216591026284 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591026285 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591026286 putative substrate translocation pore; other site 216591026287 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.6e-52 216591026288 13 probable transmembrane helices predicted for BCAM1752 by TMHMM2.0 at aa 60-82, 89-111, 115-137, 149-171, 175-197, 209-226, 231-253, 273-295, 310-332, 339-361, 371-393, 406-425 and 440-462 216591026289 Probable gene remnant. Similar to the C-terminal region of Rhizobium loti (mesorhizobium loti) probable transcriptional regulator UniProt:Q98I96 (EMBL:BA000012 (299 aa) fasta scores: E()=3.8e-06, 58.000% id in 50 aa 216591026290 Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792 216591026291 Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659 216591026292 Sulfate transporter family; Region: Sulfate_transp; pfam00916 216591026293 Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042 216591026294 HMMPfam hit to PF01740, STAS domain, score 9.6e-14 216591026295 HMMPfam hit to PF00916, Sulfate transporter family, score 4.2e-53 216591026296 10 probable transmembrane helices predicted for BCAM1753A by TMHMM2.0 at aa 58-80, 100-122, 134-156, 189-208, 215-237, 261-283, 296-318, 333-352, 359-381 and 391-413 216591026297 Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668 216591026298 Mechanosensitive ion channel; Region: MS_channel; pfam00924 216591026299 5 probable transmembrane helices predicted for BCAM1754 by TMHMM2.0 at aa 10-32, 64-86, 90-112, 124-146 and 161-183 216591026300 HMMPfam hit to PF00924, Mechanosensitive ion channel, score 6e-31 216591026301 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591026302 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591026303 DNA-binding site [nucleotide binding]; DNA binding site 216591026304 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591026305 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591026306 homodimer interface [polypeptide binding]; other site 216591026307 catalytic residue [active] 216591026308 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.6e-08 216591026309 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 8.6e-12 216591026310 oxidoreductase alpha (molybdopterin) subunit; Region: Fdhalpha-like; TIGR01701 216591026311 The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767 216591026312 putative molybdopterin cofactor binding site [chemical binding]; other site 216591026313 The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787 216591026314 putative molybdopterin cofactor binding site; other site 216591026315 HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 2.8e-12 216591026316 HMMPfam hit to PF01568, Molydopterin dinucleotide binding dom, score 2.2e-08 216591026317 Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062 216591026318 HMMPfam hit to PF05249, Uncharacterised protein family (UPF0187), score 8.6e-106 216591026319 3 probable transmembrane helices predicted for BCAM1757 by TMHMM2.0 at aa 13-35, 50-70 and 226-248 216591026320 Fusaric acid resistance protein family; Region: FUSC; pfam04632 216591026321 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 216591026322 Fusaric acid resistance protein family; Region: FUSC; pfam04632 216591026323 10 probable transmembrane helices predicted for BCAM1758 by TMHMM2.0 at aa 26-48, 79-98, 103-122, 129-151, 161-183, 365-387, 392-409, 416-438, 442-464 and 496-518 216591026324 HMMPfam hit to PF04632, Fusaric acid resistance protein conserved re, score 5.8e-39 216591026325 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591026326 LysR family transcriptional regulator; Provisional; Region: PRK14997 216591026327 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026328 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591026329 putative effector binding pocket; other site 216591026330 dimerization interface [polypeptide binding]; other site 216591026331 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.8e-17 216591026332 Predicted helix-turn-helix motif with score 1046.000, SD 2.75 at aa 16-37, sequence GSFTAASVELDMPLSRVSRKVK 216591026333 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.9e-41 216591026334 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591026335 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591026336 putative substrate translocation pore; other site 216591026337 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591026338 13 probable transmembrane helices predicted for BCAM1760 by TMHMM2.0 at aa 13-35, 55-77, 84-103, 113-135, 142-164, 170-192, 204-221, 231-253, 272-294, 309-331, 338-355, 370-392 and 483-500 216591026339 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.1e-56 216591026340 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591026341 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512 216591026342 Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496 216591026343 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 7.4e-64 216591026344 PS00284 Serpins signature. 216591026345 Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845 216591026346 Natural resistance-associated macrophage protein; Region: Nramp; pfam01566 216591026347 11 probable transmembrane helices predicted for BCAM1764 by TMHMM2.0 at aa 36-55, 70-92, 113-135, 150-168, 175-197, 217-239, 265-287, 307-329, 349-371, 375-397 and 410-432 216591026348 HMMPfam hit to PF01566, Natural resistance-associated macrophage pro, score 1.7e-123 216591026349 bicupin, oxalate decarboxylase family; Region: bicupin_oxalic; TIGR03404 216591026350 Cupin; Region: Cupin_1; smart00835 216591026351 Cupin; Region: Cupin_1; smart00835 216591026352 HMMPfam hit to PF00190, Cupin, score 7.2e-26 216591026353 HMMPfam hit to PF07883, Cupin domain, score 4.9e-14 216591026354 HMMPfam hit to PF00190, Cupin, score 3.1e-18 216591026355 HMMPfam hit to PF07883, Cupin domain, score 2.8e-11 216591026356 HipA N-terminal domain; Region: Couple_hipA; pfam13657 216591026357 Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550 216591026358 HipA-like N-terminal domain; Region: HipA_N; pfam07805 216591026359 HipA-like C-terminal domain; Region: HipA_C; pfam07804 216591026360 HMMPfam hit to PF07804, HipA-like C-terminal domain, score 2.5e-36 216591026361 HMMPfam hit to PF07805, HipA-like N-terminal domain, score 7.2e-22 216591026362 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 216591026363 non-specific DNA binding site [nucleotide binding]; other site 216591026364 salt bridge; other site 216591026365 HMMPfam hit to PF01381, Helix-turn-helix, score 2.1e-07 216591026366 Predicted helix-turn-helix motif with score 1745.000, SD 5.13 at aa 24-45, sequence LTQAEAAARIGVGQSRLSSLET 216591026367 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 216591026368 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 216591026369 SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389 216591026370 D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178 216591026371 HMMPfam hit to PF01427, D-ala-D-ala dipeptidase, score 1.7e-43 216591026372 HMMPfam hit to PF02557, D-alanyl-D-alanine carboxypeptidase, score 1e-06 216591026373 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512 216591026374 Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496 216591026375 1 probable transmembrane helix predicted for BCAM1770 by TMHMM2.0 at aa 7-26 216591026376 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 3e-69 216591026377 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 216591026378 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591026379 dimer interface [polypeptide binding]; other site 216591026380 conserved gate region; other site 216591026381 putative PBP binding loops; other site 216591026382 ABC-ATPase subunit interface; other site 216591026383 7 probable transmembrane helices predicted for BCAM1771 by TMHMM2.0 at aa 27-49, 121-143, 156-178, 221-240, 270-292, 297-319 and 326-348 216591026384 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.4e-47 216591026385 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173 216591026386 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591026387 dimer interface [polypeptide binding]; other site 216591026388 conserved gate region; other site 216591026389 putative PBP binding loops; other site 216591026390 ABC-ATPase subunit interface; other site 216591026391 6 probable transmembrane helices predicted for BCAM1772 by TMHMM2.0 at aa 40-62, 108-130, 151-173, 210-227, 232-249 and 269-291 216591026392 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.8e-43 216591026393 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124 216591026394 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591026395 Walker A/P-loop; other site 216591026396 ATP binding site [chemical binding]; other site 216591026397 Q-loop/lid; other site 216591026398 ABC transporter signature motif; other site 216591026399 Walker B; other site 216591026400 D-loop; other site 216591026401 H-loop/switch region; other site 216591026402 HMMPfam hit to PF00005, ABC transporter score 2.9e-48 216591026403 PS00017 ATP/GTP-binding site motif A (P-loop). 216591026404 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124 216591026405 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591026406 Walker A/P-loop; other site 216591026407 ATP binding site [chemical binding]; other site 216591026408 Q-loop/lid; other site 216591026409 ABC transporter signature motif; other site 216591026410 Walker B; other site 216591026411 D-loop; other site 216591026412 H-loop/switch region; other site 216591026413 HMMPfam hit to PF00005, ABC transporter score 3.7e-69 216591026414 PS00017 ATP/GTP-binding site motif A (P-loop). 216591026415 PS00211 ABC transporters family signature. 216591026416 Predicted membrane protein [Function unknown]; Region: COG2261 216591026417 3 probable transmembrane helices predicted for BCAM1775 by TMHMM2.0 at aa 4-21, 28-50 and 60-79 216591026418 HMMPfam hit to PF04226, Transglycosylase associated protein, score 2e-08 216591026419 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591026420 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591026421 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591026422 HMMPfam hit to PF01527, Transposase, score 0.0012 216591026423 Predicted helix-turn-helix motif with score 1296.000, SD 3.60 at aa 21-42, sequence AGTKTLAHRYGVGRTMVRRWVA 216591026424 HMMPfam hit to PF02178, AT hook motif, score 0.016 216591026425 putative transposase OrfB; Reviewed; Region: PHA02517 216591026426 HTH-like domain; Region: HTH_21; pfam13276 216591026427 Integrase core domain; Region: rve; pfam00665 216591026428 Integrase core domain; Region: rve_2; pfam13333 216591026429 PS00228 Tubulin-beta mRNA autoregulation signal. 216591026430 Predicted helix-turn-helix motif with score 1108.000, SD 2.96 at aa 8-29, sequence HPVAALLKAAGLARSTFYYQLK 216591026431 HMMPfam hit to PF00665, Integrase core domain, score 3.8e-47 216591026432 1 probable transmembrane helix predicted for BCAM1777A by TMHMM2.0 at aa 5-27 216591026433 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591026434 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026435 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591026436 substrate binding pocket [chemical binding]; other site 216591026437 dimerization interface [polypeptide binding]; other site 216591026438 HMMPfam hit to PF03466, LysR substrate binding domain, score 5e-32 216591026439 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.5e-21 216591026440 PS00044 Bacterial regulatory proteins, lysR family signature. 216591026441 Predicted helix-turn-helix motif with score 2081.000, SD 6.27 at aa 20-41, sequence RSFTRAAEQLCITQGAVSRQIQ 216591026442 Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354 216591026443 HMMPfam hit to PF00144, Beta-lactamase, score 6.4e-29 216591026444 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591026445 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 216591026446 Peptidase family M23; Region: Peptidase_M23; pfam01551 216591026447 HMMPfam hit to PF01551, Peptidase family M23, score 7e-36 216591026448 HMMPfam hit to PF01476, LysM domain, score 3.6e-13 216591026449 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591026450 1 probable transmembrane helix predicted for BCAM1780A by TMHMM2.0 at aa 26-48 216591026451 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591026452 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026453 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421 216591026454 putative dimerization interface [polypeptide binding]; other site 216591026455 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2e-15 216591026456 PS00044 Bacterial regulatory proteins, lysR family signature. 216591026457 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.2e-41 216591026458 Predicted ester cyclase [General function prediction only]; Region: COG5485 216591026459 HMMPfam hit to PF07366, SnoaL-like polyketide cyclase, score 1.1e-51 216591026460 PS00017 ATP/GTP-binding site motif A (P-loop). 216591026461 7 probable transmembrane helices predicted for BCAM1784 by TMHMM2.0 at aa 13-35, 50-72, 79-98, 103-125, 132-154, 169-186 and 231-248 216591026462 HMMPfam hit to PF01925, Domain of unknown function DUF81, score 3.2e-34 216591026463 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591026464 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 216591026465 active site 216591026466 catalytic tetrad [active] 216591026467 HMMPfam hit to PF00248, Aldo/keto reductase family, score 4.1e-46 216591026468 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591026469 transcriptional regulator; Provisional; Region: PRK10632 216591026470 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026471 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472 216591026472 putative effector binding pocket; other site 216591026473 putative dimerization interface [polypeptide binding]; other site 216591026474 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.8e-16 216591026475 Predicted helix-turn-helix motif with score 1739.000, SD 5.11 at aa 17-38, sequence GSFTKAAEQLQLPRPTVSNAVQ 216591026476 PS00044 Bacterial regulatory proteins, lysR family signature. 216591026477 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.8e-44 216591026478 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591026479 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591026480 trimer interface [polypeptide binding]; other site 216591026481 eyelet of channel; other site 216591026482 HMMPfam hit to PF00267, Gram-negative porin, score 9e-06 216591026483 1 probable transmembrane helix predicted for BCAM1787 by TMHMM2.0 at aa 5-27 216591026484 OpgC protein; Region: OpgC_C; pfam10129 216591026485 8 probable transmembrane helices predicted for BCAM1788 by TMHMM2.0 at aa 13-35, 50-67, 87-109, 141-163, 228-247, 262-284, 305-324 and 339-361 216591026486 S-formylglutathione hydrolase; Region: PLN02442 216591026487 Putative esterase; Region: Esterase; pfam00756 216591026488 HMMPfam hit to PF00756, Putative esterase, score 1.3e-23 216591026489 PS00041 Bacterial regulatory proteins, araC family signature. 216591026490 Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303 216591026491 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 216591026492 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2.5e-05 216591026493 HMMPfam hit to PF00732, GMC oxidoreductase, score 2.7e-05 216591026494 Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318 216591026495 1 probable transmembrane helix predicted for BCAM1791 by TMHMM2.0 at aa 20-42 216591026496 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591026497 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591026498 Cytochrome c; Region: Cytochrom_C; pfam00034 216591026499 HMMPfam hit to PF00034, Cytochrome c, score 0.013 216591026500 PS00190 Cytochrome c family heme-binding site signature. 216591026501 PS00190 Cytochrome c family heme-binding site signature. 216591026502 PS00190 Cytochrome c family heme-binding site signature. 216591026503 CDS contains a nonsense mutation (amber) after codon 125 216591026504 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.5e-06 216591026505 PS00061 Short-chain dehydrogenases/reductases family signature. 216591026506 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591026507 Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702 216591026508 NAD(P) binding site [chemical binding]; other site 216591026509 active site 216591026510 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0034 216591026511 HMMPfam hit to PF05368, NmrA-like family, score 9.9e-10 216591026512 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591026513 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026514 The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417 216591026515 substrate binding pocket [chemical binding]; other site 216591026516 dimerization interface [polypeptide binding]; other site 216591026517 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.7e-17 216591026518 Predicted helix-turn-helix motif with score 1197.000, SD 3.26 at aa 27-48, sequence RSVTRAGMRLGLTQPAASRALG 216591026519 PS00044 Bacterial regulatory proteins, lysR family signature. 216591026520 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.1e-20 216591026521 Ion channel; Region: Ion_trans_2; pfam07885 216591026522 K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569 216591026523 TrkA-N domain; Region: TrkA_N; pfam02254 216591026524 HMMPfam hit to PF02254, TrkA-N domain, score 7.5e-31 216591026525 HMMPfam hit to PF07885, Ion channel, score 1.9e-10 216591026526 3 probable transmembrane helices predicted for BCAM1797 by TMHMM2.0 at aa 42-61, 76-98 and 110-132 216591026527 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591026528 hydroxyglutarate oxidase; Provisional; Region: PRK11728 216591026529 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2e-95 216591026530 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 0.00095 216591026531 1 probable transmembrane helix predicted for BCAM1798 by TMHMM2.0 at aa 20-42 216591026532 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591026533 BetR domain; Region: BetR; pfam08667 216591026534 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736 216591026535 active site 216591026536 phosphorylation site [posttranslational modification] 216591026537 intermolecular recognition site; other site 216591026538 dimerization interface [polypeptide binding]; other site 216591026539 Predicted helix-turn-helix motif with score 992.000, SD 2.57 at aa 30-51, sequence QQTTELCRILDLSFSQGHRKLR 216591026540 Part of AAA domain; Region: AAA_19; pfam13245 216591026541 Family description; Region: UvrD_C_2; pfam13538 216591026542 PS00017 ATP/GTP-binding site motif A (P-loop). 216591026543 Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729 216591026544 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181 216591026545 dimer interface [polypeptide binding]; other site 216591026546 ligand binding site [chemical binding]; other site 216591026547 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591026548 dimerization interface [polypeptide binding]; other site 216591026549 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591026550 dimer interface [polypeptide binding]; other site 216591026551 putative CheW interface [polypeptide binding]; other site 216591026552 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 8.8e-96 216591026553 PS00538 Bacterial chemotaxis sensory transducers signature. 216591026554 HMMPfam hit to PF00672, HAMP domain, score 8.4e-11 216591026555 2 probable transmembrane helices predicted for BCAM1804 by TMHMM2.0 at aa 15-37 and 198-220 216591026556 methyl viologen resistance protein SmvA; Provisional; Region: PRK14995 216591026557 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591026558 putative substrate translocation pore; other site 216591026559 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591026560 14 probable transmembrane helices predicted for BCAM1805 by TMHMM2.0 at aa 20-42, 62-81, 88-107, 117-139, 151-170, 175-197, 210-227, 240-257, 277-299, 314-336, 343-365, 375-397, 410-432 and 473-495 216591026561 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.3e-64 216591026562 quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754 216591026563 Quinone oxidoreductase (QOR); Region: QOR2; cd05286 216591026564 NADP binding site [chemical binding]; other site 216591026565 dimer interface [polypeptide binding]; other site 216591026566 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 7e-33 216591026567 PS01162 Quinone oxidoreductase / zeta-crystallin signature. 216591026568 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 4e-20 216591026569 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591026570 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026571 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591026572 dimerization interface [polypeptide binding]; other site 216591026573 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.6e-17 216591026574 Predicted helix-turn-helix motif with score 1267.000, SD 3.50 at aa 16-37, sequence GSLSAAARALQVQHSTVARRID 216591026575 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.2e-30 216591026576 Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247 216591026577 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.5e-13 216591026578 Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg2; cd04778 216591026579 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 216591026580 DNA binding residues [nucleotide binding] 216591026581 putative dimer interface [polypeptide binding]; other site 216591026582 HMMPfam hit to PF00376, MerR family regulatory protein, score 2.6e-07 216591026583 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 216591026584 DNA-binding site [nucleotide binding]; DNA binding site 216591026585 RNA-binding motif; other site 216591026586 HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 4e-38 216591026587 PS00352 'Cold-shock' DNA-binding domain signature. 216591026588 Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592 216591026589 oligomer interface [polypeptide binding]; other site 216591026590 putative active site [active] 216591026591 Mn binding site [ion binding]; other site 216591026592 HMMPfam hit to PF00491, Arginase family, score 1.3e-66 216591026593 PS01053 Arginase family signature 3. 216591026594 PS00148 Arginase family signature 2. 216591026595 PS00147 Arginase family signature 1. 216591026596 YhhN-like protein; Region: YhhN; pfam07947 216591026597 6 probable transmembrane helices predicted for BCAM1813 by TMHMM2.0 at aa 35-57, 105-127, 134-156, 160-182, 189-211 and 215-237 216591026598 HMMPfam hit to PF07947, YhhN-like protein, score 1.3e-35 216591026599 Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072 216591026600 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738 216591026601 short chain dehydrogenase; Provisional; Region: PRK07832 216591026602 classical (c) SDRs; Region: SDR_c; cd05233 216591026603 NAD(P) binding site [chemical binding]; other site 216591026604 active site 216591026605 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.7e-24 216591026606 PS00061 Short-chain dehydrogenases/reductases family signature. 216591026607 Predicted metal-dependent hydrolase; Region: Metal_hydrol; pfam10118 216591026608 Predicted metal-dependent hydrolase [General function prediction only]; Region: COG3687 216591026609 1 probable transmembrane helix predicted for BCAM1816 by TMHMM2.0 at aa 183-205 216591026610 PS00213 Lipocalin signature. 216591026611 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591026612 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591026613 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 3.8e-18 216591026614 Putative glycolipid-binding; Region: Glycolipid_bind; pfam06475 216591026615 HMMPfam hit to PF06475, Protein of unknown function (DUF1089), score 5.8e-74 216591026616 Urea transporter; Region: UT; cl01829 216591026617 HMMPfam hit to PF03253, Urea transporter score 5e-14 216591026618 7 probable transmembrane helices predicted for BCAM1819 by TMHMM2.0 at aa 15-37, 44-66, 81-112, 125-147, 169-191, 198-220 and 256-278 216591026619 aldolase II superfamily protein; Provisional; Region: PRK07044 216591026620 intersubunit interface [polypeptide binding]; other site 216591026621 active site 216591026622 Zn2+ binding site [ion binding]; other site 216591026623 HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 3.2e-54 216591026624 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591026625 4-oxalocrotonate tautomerase; Provisional; Region: PRK00745 216591026626 active site 1 [active] 216591026627 dimer interface [polypeptide binding]; other site 216591026628 hexamer interface [polypeptide binding]; other site 216591026629 active site 2 [active] 216591026630 HMMPfam hit to PF01361, Tautomerase enzyme, score 3.5e-12 216591026631 Bacterial NAD-glutamate dehydrogenase; Region: Bac_GDH; pfam05088 216591026632 HMMPfam hit to PF05088, Bacterial NAD-glutamate dehydrogenase, score 0 216591026633 Predicted helix-turn-helix motif with score 1101.000, SD 2.94 at aa 785-806, sequence RTNYFLADANGESKPYLSFKFN 216591026634 O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3315 216591026635 Leucine carboxyl methyltransferase; Region: LCM; pfam04072 216591026636 HMMPfam hit to PF02409, O-methyltransferase N-terminus, score 6.8e-08 216591026637 Glyoxalase-like domain; Region: Glyoxalase_2; pfam12681 216591026638 N-acetyltransferase; Region: Acetyltransf_2; pfam00797 216591026639 HMMPfam hit to PF00797, N-acetyltransferase, score 2.1e-108 216591026640 amidase; Provisional; Region: PRK07486 216591026641 Amidase; Region: Amidase; pfam01425 216591026642 HMMPfam hit to PF01425, Amidase, score 8.2e-97 216591026643 PS00571 Amidases signature. 216591026644 PS00017 ATP/GTP-binding site motif A (P-loop). 216591026645 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 216591026646 Ligand Binding Site [chemical binding]; other site 216591026647 SnoaL-like domain; Region: SnoaL_2; pfam12680 216591026648 HMMPfam hit to PF07858, Limonene-1,2-epoxide hydrolase catalytic dom, score 0.0016 216591026649 HMMPfam hit to PF07366, SnoaL-like polyketide cyclase, score 4.1e-06 216591026650 Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Saccharomyces cerevisiae biotin-apoprotein ligase (ScBLP); Region: GATase1_ScBLP_like; cd03144 216591026651 conserved cys residue [active] 216591026652 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238 216591026653 Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576 216591026654 substrate binding site [chemical binding]; other site 216591026655 Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581 216591026656 substrate binding site [chemical binding]; other site 216591026657 ligand binding site [chemical binding]; other site 216591026658 HMMPfam hit to PF06434, Aconitate hydratase, score 2.5e-278 216591026659 HMMPfam hit to PF00330, Aconitase family (aconitate hydratase), score 9.3e-12 216591026660 PS00450 Aconitase family signature 1. 216591026661 Domain of unknown function (DUF4274); Region: DUF4274; pfam14096 216591026662 Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378 216591026663 trimer interface [polypeptide binding]; other site 216591026664 putative Zn binding site [ion binding]; other site 216591026665 HMMPfam hit to PF03479, Domain of unknown function (DUF296), score 1.8e-14 216591026666 2 probable transmembrane helices predicted for BCAM1836 by TMHMM2.0 at aa 77-99 and 121-143 216591026667 ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747 216591026668 HMMPfam hit to PF03747, ADP-ribosylglycohydrolase, score 2.1e-43 216591026669 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 216591026670 homotrimer interaction site [polypeptide binding]; other site 216591026671 putative active site [active] 216591026672 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 3.3e-12 216591026673 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 216591026674 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591026675 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 7.6e-08 216591026676 benzoate transport; Region: 2A0115; TIGR00895 216591026677 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591026678 putative substrate translocation pore; other site 216591026679 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591026680 HMMPfam hit to PF00083, Sugar (and other) transporter score 1e-25 216591026681 12 probable transmembrane helices predicted for BCAM1841 by TMHMM2.0 at aa 43-65, 75-97, 104-126, 130-152, 165-187, 191-213, 279-301, 316-335, 342-364, 368-390, 403-422 and 432-454 216591026682 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.7e-44 216591026683 PS00216 Sugar transport proteins signature 1. 216591026684 PS00217 Sugar transport proteins signature 2. 216591026685 phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754 216591026686 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591026687 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 7e-45 216591026688 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 3.8e-28 216591026689 2,3-dihydroxybiphenyl 1,2-dioxygenase; Region: 23dbph12diox; TIGR03213 216591026690 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 216591026691 active site 216591026692 metal binding site [ion binding]; metal-binding site 216591026693 C-terminal domain of Burkholderia sp. NF100 MhqB and similar proteins; MhqB is a type I extradiol dioxygenase involved in the catabolism of methylhydroquinone, an intermediate in the degradation of fenitrothion; Region: MhqB_like_C; cd08360 216591026694 putative active site [active] 216591026695 putative metal binding site [ion binding]; other site 216591026696 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 1.8e-09 216591026697 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591026698 Uncharacterized Candidatus pelagibacter aldehyde dehydrogenase, DhaS-like; Region: ALDH_DhaS; cd07114 216591026699 NAD(P) binding site [chemical binding]; other site 216591026700 catalytic residues [active] 216591026701 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.1e-234 216591026702 PS00070 Aldehyde dehydrogenases cysteine active site. 216591026703 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591026704 L-aspartate dehydrogenase; Provisional; Region: PRK13303 216591026705 Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447 216591026706 Domain of unknown function DUF108; Region: DUF108; pfam01958 216591026707 HMMPfam hit to PF01958, Domain of unknown function DUF108, score 9.7e-58 216591026708 HMMPfam hit to PF03447, Homoserine dehydrogenase, NAD binding d, score 1.9e-11 216591026709 hypothetical protein; Provisional; Region: PRK07064 216591026710 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 216591026711 PYR/PP interface [polypeptide binding]; other site 216591026712 dimer interface [polypeptide binding]; other site 216591026713 TPP binding site [chemical binding]; other site 216591026714 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591026715 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568 216591026716 TPP-binding site [chemical binding]; other site 216591026717 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 3.2e-35 216591026718 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 4e-07 216591026719 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591026720 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 2e-28 216591026721 short chain dehydrogenase; Provisional; Region: PRK07062 216591026722 putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR; Region: BKR_like_SDR_like; cd05344 216591026723 putative NAD(P) binding site [chemical binding]; other site 216591026724 putative active site [active] 216591026725 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.9e-13 216591026726 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 216591026727 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591026728 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591026729 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 3.7e-10 216591026730 Predicted helix-turn-helix motif with score 1389.000, SD 3.92 at aa 41-62, sequence LGAPELSKRLGIPRTTVFRLLQ 216591026731 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591026732 Serine hydrolase; Region: Ser_hydrolase; cl17834 216591026733 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 3.3e-20 216591026734 Cupin domain; Region: Cupin_2; pfam07883 216591026735 HMMPfam hit to PF07883, Cupin domain, score 9.4e-11 216591026736 short chain dehydrogenase; Provisional; Region: PRK12939 216591026737 classical (c) SDRs; Region: SDR_c; cd05233 216591026738 NAD(P) binding site [chemical binding]; other site 216591026739 active site 216591026740 HMMPfam hit to PF00106, short chain dehydrogenase, score 6.4e-21 216591026741 PS00061 Short-chain dehydrogenases/reductases family signature. 216591026742 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 216591026743 Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469 216591026744 [2Fe-2S] cluster binding site [ion binding]; other site 216591026745 START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643 216591026746 hydrophobic ligand binding site; other site 216591026747 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 7.9e-26 216591026748 Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528 216591026749 [2Fe-2S] cluster binding site [ion binding]; other site 216591026750 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 2e-21 216591026751 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591026752 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591026753 trimer interface [polypeptide binding]; other site 216591026754 eyelet of channel; other site 216591026755 HMMPfam hit to PF00267, Gram-negative porin, score 9.4e-06 216591026756 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 216591026757 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591026758 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591026759 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 3.1e-20 216591026760 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_2; pfam13532 216591026761 HMMPfam hit to PF03171, 2OG-Fe(II) oxygenase superfamily, score 0.0012 216591026762 Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385 216591026763 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 216591026764 putative active site [active] 216591026765 putative metal binding site [ion binding]; other site 216591026766 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1.9e-16 216591026767 4 probable transmembrane helices predicted for BCAM1861 by TMHMM2.0 at aa 3-25, 35-57, 64-86 and 113-132 216591026768 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591026769 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026770 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421 216591026771 putative dimerization interface [polypeptide binding]; other site 216591026772 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 8.9e-17 216591026773 PS00044 Bacterial regulatory proteins, lysR family signature. 216591026774 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.6e-40 216591026775 3 probable transmembrane helices predicted for BCAM1863 by TMHMM2.0 at aa 12-30, 40-62 and 74-96 216591026776 multidrug resistance protein MdtN; Provisional; Region: PRK10476 216591026777 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591026778 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591026779 1 probable transmembrane helix predicted for BCAM1864 by TMHMM2.0 at aa 13-32 216591026780 HMMPfam hit to PF00529, HlyD family secretion protein, score 8.1e-32 216591026781 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 216591026782 9 probable transmembrane helices predicted for BCAM1865 by TMHMM2.0 at aa 28-50, 71-93, 98-117, 124-143, 153-175, 416-438, 442-464, 469-491 and 501-520 216591026783 type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844 216591026784 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591026785 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.1e-26 216591026786 HMMPfam hit to PF02321, Outer membrane efflux protein, score 7.1e-32 216591026787 Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285 216591026788 MgtC family; Region: MgtC; pfam02308 216591026789 4 probable transmembrane helices predicted for BCAM1867 by TMHMM2.0 at aa 5-22, 29-51, 56-78 and 91-113 216591026790 HMMPfam hit to PF02308, MgtC family, score 3.3e-46 216591026791 DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188 216591026792 Autoinducer binding domain; Region: Autoind_bind; pfam03472 216591026793 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591026794 DNA binding residues [nucleotide binding] 216591026795 dimerization interface [polypeptide binding]; other site 216591026796 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 3.7e-23 216591026797 PS00622 Bacterial regulatory proteins, luxR family signature. 216591026798 Predicted helix-turn-helix motif with score 1403.000, SD 3.97 at aa 191-212, sequence KTACEIGQILSISERTVNFHVN 216591026799 HMMPfam hit to PF03472, Autoinducer binding domain, score 1.4e-48 216591026800 Autoinducer synthetase; Region: Autoind_synth; cl17404 216591026801 HMMPfam hit to PF00765, Autoinducer synthetase, score 3.6e-12 216591026802 Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase; cl00205 216591026803 2 probable transmembrane helices predicted for BCAM1872 by TMHMM2.0 at aa 28-50 and 65-87 216591026804 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587 216591026805 active site 216591026806 metal binding site [ion binding]; metal-binding site 216591026807 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591026808 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 4.6e-05 216591026809 HMMPfam hit to PF00925, GTP cyclohydrolase II, score 2.6e-97 216591026810 BcenGI13 216591026811 Virulence-associated protein E; Region: VirE; pfam05272 216591026812 HMMPfam hit to PF05272, Virulence-associated protein E, score 9.4e-31 216591026813 PS00017 ATP/GTP-binding site motif A (P-loop). 216591026814 HMMPfam hit to PF01402, Ribbon-helix-helix protein, copG family, score 0.00029 216591026815 1 probable transmembrane helix predicted for BCAM1878A by TMHMM2.0 at aa 7-29 216591026816 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591026817 Prophage antirepressor [Transcription]; Region: COG3617 216591026818 BRO family, N-terminal domain; Region: Bro-N; smart01040 216591026819 Phage antirepressor protein KilAC domain; Region: ANT; cl01462 216591026820 HMMPfam hit to PF02498, BRO family, N-terminal domain, score 3.1e-23 216591026821 ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell; Region: ADP_ribosyl; cl00283 216591026822 Protein of unknown function DUF72; Region: DUF72; pfam01904 216591026823 HMMPfam hit to PF01904, Protein of unknown function DUF72, score 4.2e-63 216591026824 H-NS histone family; Region: Histone_HNS; pfam00816 216591026825 Domain in histone-like proteins of HNS family; Region: HNS; smart00528 216591026826 HNH endonuclease; Region: HNH_3; pfam13392 216591026827 HMMPfam hit to PF01844, HNH endonuclease, score 1.1e-07 216591026828 Terminase-like family; Region: Terminase_6; pfam03237 216591026829 chromosome segregation protein; Provisional; Region: PRK03918 216591026830 1 probable transmembrane helix predicted for BCAM1897 by TMHMM2.0 at aa 86-108 216591026831 phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644 216591026832 PS00217 Sugar transport proteins signature 2. 216591026833 1 probable transmembrane helix predicted for BCAM1904 by TMHMM2.0 at aa 102-124 216591026834 PS00287 Cysteine proteases inhibitors signature. 216591026835 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 216591026836 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 216591026837 Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586 216591026838 HMMPfam hit to PF01609, Transposase DDE domain, score 1.3e-29 216591026839 Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900 216591026840 SPRY domain; Region: SPRY; cl02614 216591026841 SPRY domain-like in bacteria; Region: SPRY_like; cd12886 216591026842 HMMPfam hit to PF00622, SPRY domain, score 0.00081 216591026843 Transposase; Region: HTH_Tnp_1; pfam01527 216591026844 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591026845 CDS lacks appropriate translational start site. It is likely that this CDS encodes the C-terminal region of a larger protein encompassing the upstream CDS. A translational frameshift possibly occurs after residue 86 of the upstream overlapping CDS 216591026846 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591026847 lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222 216591026848 catalytic residue [active] 216591026849 Domain of unknown function (DUF4279); Region: DUF4279; pfam14106 216591026850 1 probable transmembrane helix predicted for BCAM1921 by TMHMM2.0 at aa 78-100 216591026851 Helix-turn-helix domain; Region: HTH_36; pfam13730 216591026852 Predicted helix-turn-helix motif with score 1451.000, SD 4.13 at aa 63-84, sequence MSHAAIAQCMDIAERTVRNAID 216591026853 Similar to Rhodopseudomonas palustris phage integrase SWALL:Q6N160 (EMBL:BX572607) (460 aa) fasta scores: E(): 5.3, 24.6% id in 439 aa. CDS is disrupted by the insertion of an IS element after codon 61 216591026854 HMMPfam hit to PF00589, Phage integrase family, score 4.3e-05 216591026855 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 216591026856 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 216591026857 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 216591026858 Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586 216591026859 HMMPfam hit to PF01609, Transposase DDE domain, score 3.6e-32 216591026860 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_10; cd04623 216591026861 FOG: CBS domain [General function prediction only]; Region: COG0517 216591026862 HMMPfam hit to PF00571, CBS domain pair, score 1.4e-30 216591026863 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591026864 nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753 216591026865 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 216591026866 HMMPfam hit to PF01272, Prokaryotic transcription elongation factor, score 6.5e-05 216591026867 putative transposase OrfB; Reviewed; Region: PHA02517 216591026868 Integrase core domain; Region: rve; pfam00665 216591026869 Integrase core domain; Region: rve_3; pfam13683 216591026870 HMMPfam hit to PF00665, Integrase core domain, score 1.1e-35 216591026871 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591026872 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591026873 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591026874 trimer interface [polypeptide binding]; other site 216591026875 eyelet of channel; other site 216591026876 HMMPfam hit to PF00267, Gram-negative porin, score 1.8e-08 216591026877 Predicted transcriptional regulators [Transcription]; Region: COG1733 216591026878 HxlR-like helix-turn-helix; Region: HxlR; pfam01638 216591026879 HMMPfam hit to PF01638, HxlR-like helix-turn-helix, score 4.9e-28 216591026880 Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109 216591026881 HMMPfam hit to PF07366, SnoaL-like polyketide cyclase, score 5.6e-11 216591026882 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591026883 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591026884 DNA binding residues [nucleotide binding] 216591026885 dimerization interface [polypeptide binding]; other site 216591026886 HMMPfam hit to PF08281, Sigma-70, region, score 0.0016 216591026887 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 9.9e-13 216591026888 PS00622 Bacterial regulatory proteins, luxR family signature. 216591026889 Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574 216591026890 YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300 216591026891 active site 216591026892 HMMPfam hit to PF07969, Amidohydrolase family, score 2.6e-74 216591026893 Isochorismatase family; Region: Isochorismatase; pfam00857 216591026894 Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014 216591026895 catalytic triad [active] 216591026896 conserved cis-peptide bond; other site 216591026897 HMMPfam hit to PF00857, Isochorismatase family, score 3.9e-15 216591026898 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591026899 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591026900 putative substrate translocation pore; other site 216591026901 12 probable transmembrane helices predicted for BCAM1937 by TMHMM2.0 at aa 36-58, 78-100, 113-135, 140-162, 174-196, 206-228, 257-279, 294-316, 328-345, 349-371, 383-405 and 410-432 216591026902 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.5e-32 216591026903 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 216591026904 active site 216591026905 metal binding site [ion binding]; metal-binding site 216591026906 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 0.0052 216591026907 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591026908 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 216591026909 NAD(P) binding site [chemical binding]; other site 216591026910 active site 216591026911 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.1e-23 216591026912 PS00216 Sugar transport proteins signature 1. 216591026913 PS00061 Short-chain dehydrogenases/reductases family signature. 216591026914 Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456 216591026915 Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133 216591026916 Na binding site [ion binding]; other site 216591026917 12 probable transmembrane helices predicted for BCAM1940 by TMHMM2.0 at aa 32-54, 59-81, 102-124, 139-161, 173-192, 207-229, 249-271, 295-317, 330-352, 362-384, 416-438 and 448-470 216591026918 HMMPfam hit to PF02133, Permease for cytosine/purines, uracil,, score 2e-23 216591026919 GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972 216591026920 GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048 216591026921 C-terminal domain interface [polypeptide binding]; other site 216591026922 GSH binding site (G-site) [chemical binding]; other site 216591026923 dimer interface [polypeptide binding]; other site 216591026924 C-terminal, alpha helical domain of Ure2p and related Glutathione S-transferase-like proteins; Region: GST_C_Ure2p_like; cd03178 216591026925 dimer interface [polypeptide binding]; other site 216591026926 N-terminal domain interface [polypeptide binding]; other site 216591026927 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 3.9e-14 216591026928 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 4.5e-12 216591026929 pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405 216591026930 MarR family; Region: MarR_2; cl17246 216591026931 HMMPfam hit to PF01047, MarR family, score 6e-08 216591026932 PS01117 Bacterial regulatory proteins, marR family signature. 216591026933 pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405 216591026934 Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017 216591026935 dimer interface [polypeptide binding]; other site 216591026936 TPP-binding site [chemical binding]; other site 216591026937 Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410 216591026938 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591026939 HMMPfam hit to PF02321, Outer membrane efflux protein, score 5.2e-31 216591026940 HMMPfam hit to PF02321, Outer membrane efflux protein, score 5.7e-33 216591026941 Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841 216591026942 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 216591026943 12 probable transmembrane helices predicted for BCAM1946 by TMHMM2.0 at aa 12-34, 343-362, 369-391, 397-419, 440-462, 472-494, 549-571, 876-898, 905-927, 932-954, 975-997 and 1012-1034 216591026944 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 216591026945 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591026946 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591026947 HMMPfam hit to PF00529, HlyD family secretion protein, score 8.2e-46 216591026948 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591026949 Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110 216591026950 redox-sensitive transcriptional activator SoxR; Region: SoxR; TIGR01950 216591026951 DNA binding residues [nucleotide binding] 216591026952 dimer interface [polypeptide binding]; other site 216591026953 [2Fe-2S] cluster binding site [ion binding]; other site 216591026954 Predicted helix-turn-helix motif with score 1539.000, SD 4.43 at aa 12-33, sequence MSIREVAARSGVPASTLRFYET 216591026955 HMMPfam hit to PF00376, MerR family regulatory protein, score 8.5e-10 216591026956 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557 216591026957 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591026958 NAD(P) binding site [chemical binding]; other site 216591026959 active site 216591026960 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00025 216591026961 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.8e-19 216591026962 PS00061 Short-chain dehydrogenases/reductases family signature. 216591026963 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591026964 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591026965 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 216591026966 dimerization interface [polypeptide binding]; other site 216591026967 substrate binding pocket [chemical binding]; other site 216591026968 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.4e-21 216591026969 Predicted helix-turn-helix motif with score 1406.000, SD 3.98 at aa 17-38, sequence LSFRRAAERLHMAQPPLSAAIR 216591026970 PS00044 Bacterial regulatory proteins, lysR family signature. 216591026971 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.1e-49 216591026972 Truncated by IS element. N terminal 83 amino acids missing. Similar to the C-terminal region ofBurkholderia cenocepacia HI2424 transcriptional regulator, TetR family UniProt:A0B1F8 (EMBL:CP000459 (219 aa) fasta scores: E()=3.8e-47, 94.030% id in 134 aa 216591026973 putative transposase OrfB; Reviewed; Region: PHA02517 216591026974 HTH-like domain; Region: HTH_21; pfam13276 216591026975 Integrase core domain; Region: rve; pfam00665 216591026976 Integrase core domain; Region: rve_3; pfam13683 216591026977 HMMPfam hit to PF00665, Integrase core domain, score 9.5e-40 216591026978 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 216591026979 DNA-binding interface [nucleotide binding]; DNA binding site 216591026980 HMMPfam hit to PF01527, Transposase, score 8.2e-25 216591026981 Predicted helix-turn-helix motif with score 1325.000, SD 3.70 at aa 22-43, sequence TPVAEVCRKMGISDATFYNWRT 216591026982 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 216591026983 Sodium:dicarboxylate symporter family; Region: SDF; cl00573 216591026984 HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 6e-102 216591026985 8 probable transmembrane helices predicted for BCAM1954 by TMHMM2.0 at aa 7-26, 48-70, 82-104, 154-172, 199-221, 231-250, 302-324 and 334-356 216591026986 Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405 216591026987 Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019 216591026988 HMMPfam hit to PF01019, Gamma-glutamyltranspeptidase, score 2.7e-247 216591026989 PS00462 Gamma-glutamyltranspeptidase signature. 216591026990 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 216591026991 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 216591026992 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 216591026993 putative active site [active] 216591026994 HMMPfam hit to PF01418, Helix-turn-helix domain, rpiR family, score 5.3e-06 216591026995 Predicted helix-turn-helix motif with score 1146.000, SD 3.09 at aa 39-60, sequence GPIAQVAKQAEVSDPTVFRFVV 216591026996 HMMPfam hit to PF01380, SIS domain, score 1.6e-10 216591026997 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 216591026998 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 216591026999 Walker A/P-loop; other site 216591027000 ATP binding site [chemical binding]; other site 216591027001 Q-loop/lid; other site 216591027002 ABC transporter signature motif; other site 216591027003 Walker B; other site 216591027004 D-loop; other site 216591027005 H-loop/switch region; other site 216591027006 ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; pfam09821 216591027007 HMMPfam hit to PF00005, ABC transporter score 6.9e-57 216591027008 PS00211 ABC transporters family signature. 216591027009 PS00017 ATP/GTP-binding site motif A (P-loop). 216591027010 ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986 216591027011 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591027012 dimer interface [polypeptide binding]; other site 216591027013 conserved gate region; other site 216591027014 putative PBP binding loops; other site 216591027015 ABC-ATPase subunit interface; other site 216591027016 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591027017 putative PBP binding loops; other site 216591027018 dimer interface [polypeptide binding]; other site 216591027019 ABC-ATPase subunit interface; other site 216591027020 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 8.9e-07 216591027021 12 probable transmembrane helices predicted for BCAM1958 by TMHMM2.0 at aa 26-48, 68-90, 103-125, 135-157, 207-229, 244-266, 342-364, 384-406, 418-440, 450-472, 493-515 and 551-570 216591027022 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1e-05 216591027023 1 probable transmembrane helix predicted for BCAM1959 by TMHMM2.0 at aa 20-42 216591027024 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027025 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 216591027026 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 216591027027 active site 216591027028 metal binding site [ion binding]; metal-binding site 216591027029 1 probable transmembrane helix predicted for BCAM1960 by TMHMM2.0 at aa 20-42 216591027030 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 4.3e-09 216591027031 Plastocyanin [Energy production and conversion]; Region: PetE; COG3794 216591027032 Cupredoxin-like domain; Region: Cupredoxin_1; cl17234 216591027033 1 probable transmembrane helix predicted for BCAM1961 by TMHMM2.0 at aa 9-31 216591027034 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027035 HMMPfam hit to PF00127, Copper binding proteins, plastocyanin/azu, score 5.7e-09 216591027036 Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG3837 216591027037 HMMPfam hit to PF05899, Protein of unknown function (DUF861), score 0.0017 216591027038 HMMPfam hit to PF07883, Cupin domain, score 5.1e-25 216591027039 PS00120 Lipases, serine active site. 216591027040 Predicted phosphatases [General function prediction only]; Region: Gph; COG0546 216591027041 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591027042 motif II; other site 216591027043 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.7e-32 216591027044 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591027045 dimerization interface [polypeptide binding]; other site 216591027046 putative DNA binding site [nucleotide binding]; other site 216591027047 putative Zn2+ binding site [ion binding]; other site 216591027048 HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family, score 0.0004 216591027049 Predicted helix-turn-helix motif with score 1452.000, SD 4.13 at aa 62-83, sequence VCAGQIDARCGLSQSTVSAHLA 216591027050 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 216591027051 Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933 216591027052 FMN binding site [chemical binding]; other site 216591027053 active site 216591027054 substrate binding site [chemical binding]; other site 216591027055 catalytic residue [active] 216591027056 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 2.8e-93 216591027057 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591027058 Coenzyme A binding pocket [chemical binding]; other site 216591027059 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.9e-13 216591027060 Catalytic domain of Bacillus cereus phosphatidylinositol-specific phospholipases C and similar proteins; Region: PI-PLCc_BcPLC_like; cd08586 216591027061 active site 216591027062 catalytic site [active] 216591027063 putative metal binding site [ion binding]; other site 216591027064 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 216591027065 HMMPfam hit to PF00388, Phosphatidylinositol-specific phospholipase, score 5.2e-07 216591027066 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591027067 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591027068 DNA binding site [nucleotide binding] 216591027069 domain linker motif; other site 216591027070 Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_2; cd06278 216591027071 putative dimerization interface [polypeptide binding]; other site 216591027072 putative ligand binding site [chemical binding]; other site 216591027073 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 3.9e-07 216591027074 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 216591027075 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591027076 dimer interface [polypeptide binding]; other site 216591027077 conserved gate region; other site 216591027078 putative PBP binding loops; other site 216591027079 ABC-ATPase subunit interface; other site 216591027080 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3e-15 216591027081 7 probable transmembrane helices predicted for BCAM1971 by TMHMM2.0 at aa 20-42, 79-101, 114-136, 146-168, 190-212, 217-239 and 251-273 216591027082 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591027083 ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178 216591027084 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591027085 dimer interface [polypeptide binding]; other site 216591027086 conserved gate region; other site 216591027087 putative PBP binding loops; other site 216591027088 ABC-ATPase subunit interface; other site 216591027089 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.1e-15 216591027090 4 probable transmembrane helices predicted for BCAM1972 by TMHMM2.0 at aa 7-29, 72-94, 101-123 and 259-281 216591027091 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591027092 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 216591027093 Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416 216591027094 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 2.6e-27 216591027095 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591027096 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591027097 trimer interface [polypeptide binding]; other site 216591027098 eyelet of channel; other site 216591027099 HMMPfam hit to PF00267, Gram-negative porin, score 6.8e-05 216591027100 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591027101 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591027102 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00013 216591027103 PS00041 Bacterial regulatory proteins, araC family signature. 216591027104 Protein of unknown function (DUF3156); Region: DUF3156; pfam11354 216591027105 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 216591027106 HMMPfam hit to PF00324, Amino acid permease, score 9.6e-06 216591027107 13 probable transmembrane helices predicted for BCAM1977 by TMHMM2.0 at aa 4-26, 33-52, 62-84, 91-113, 128-150, 155-177, 192-214, 227-249, 286-308, 336-353, 363-385, 397-419 and 429-451 216591027108 hypothetical protein; Provisional; Region: PRK07481 216591027109 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591027110 inhibitor-cofactor binding pocket; inhibition site 216591027111 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591027112 catalytic residue [active] 216591027113 HMMPfam hit to PF00202, Aminotransferase class-III, score 3.7e-122 216591027114 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591027115 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 216591027116 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591027117 NAD(P) binding site [chemical binding]; other site 216591027118 catalytic residues [active] 216591027119 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 8.2e-231 216591027120 PS00070 Aldehyde dehydrogenases cysteine active site. 216591027121 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591027122 Predicted helix-turn-helix motif with score 1094.000, SD 2.91 at aa 208-229, sequence LRLAELAREAGVPPGVFNVVTG 216591027123 2 probable transmembrane helices predicted for BCAM1980 by TMHMM2.0 at aa 5-27 and 34-53 216591027124 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591027125 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591027126 DNA binding residues [nucleotide binding] 216591027127 dimerization interface [polypeptide binding]; other site 216591027128 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 9.6e-15 216591027129 PS00622 Bacterial regulatory proteins, luxR family signature. 216591027130 Predicted helix-turn-helix motif with score 1000.000, SD 2.59 at aa 203-224, sequence CSNKEIARDLALGQPTIKTHLM 216591027131 PS00211 ABC transporters family signature. 216591027132 Predicted metalloprotease [General function prediction only]; Region: COG2321 216591027133 Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228 216591027134 HMMPfam hit to PF04228, Putative neutral zinc metallopeptidase, score 2.2e-152 216591027135 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591027136 1 probable transmembrane helix predicted for BCAM1982 by TMHMM2.0 at aa 21-43 216591027137 classical (c) SDRs; Region: SDR_c; cd05233 216591027138 NAD(P) binding site [chemical binding]; other site 216591027139 active site 216591027140 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.2e-19 216591027141 PS00061 Short-chain dehydrogenases/reductases family signature. 216591027142 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591027143 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591027144 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591027145 dimerization interface [polypeptide binding]; other site 216591027146 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.3e-19 216591027147 Predicted helix-turn-helix motif with score 1183.000, SD 3.22 at aa 41-62, sequence ENFRLTAEKLHTTQAAVSSRIA 216591027148 PS00044 Bacterial regulatory proteins, lysR family signature. 216591027149 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.9e-38 216591027150 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591027151 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591027152 putative substrate translocation pore; other site 216591027153 HMMPfam hit to PF00083, Sugar (and other) transporter score 5.8e-09 216591027154 12 probable transmembrane helices predicted for BCAM1986 by TMHMM2.0 at aa 20-42, 57-79, 92-111, 126-148, 161-183, 193-212, 259-278, 282-304, 313-335, 340-362, 375-397 and 402-424 216591027155 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.9e-21 216591027156 PS00217 Sugar transport proteins signature 2. 216591027157 Protein of unknown function (DUF2848); Region: DUF2848; pfam11010 216591027158 1 probable transmembrane helix predicted for BCAM1988 by TMHMM2.0 at aa 10-29 216591027159 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027160 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591027161 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 216591027162 NAD(P) binding site [chemical binding]; other site 216591027163 active site 216591027164 HMMPfam hit to PF05368, NmrA-like family, score 0.0055 216591027165 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 3.1e-07 216591027166 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591027167 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591027168 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591027169 dimerization interface [polypeptide binding]; other site 216591027170 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.5e-19 216591027171 Predicted helix-turn-helix motif with score 1568.000, SD 4.53 at aa 20-41, sequence GSLSGAARALGITQPTAGRHVA 216591027172 PS00044 Bacterial regulatory proteins, lysR family signature. 216591027173 HMMPfam hit to PF03466, LysR substrate binding domain, score 8.1e-38 216591027174 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591027175 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591027176 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591027177 dimerization interface [polypeptide binding]; other site 216591027178 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.3e-14 216591027179 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.1e-21 216591027180 PS00044 Bacterial regulatory proteins, lysR family signature. 216591027181 Predicted helix-turn-helix motif with score 1767.000, SD 5.21 at aa 19-40, sequence GSLTAAAPLLHLSQSTVSEQVR 216591027182 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591027183 putative substrate translocation pore; other site 216591027184 13 probable transmembrane helices predicted for BCAM1993 by TMHMM2.0 at aa 27-49, 96-118, 122-144, 151-173, 183-205, 218-237, 242-264, 285-307, 317-339, 352-371, 381-403, 416-438 and 453-475 216591027185 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.1e-50 216591027186 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 216591027187 homotrimer interaction site [polypeptide binding]; other site 216591027188 putative active site [active] 216591027189 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 8.1e-25 216591027190 inner membrane protein; Provisional; Region: PRK11715 216591027191 HMMPfam hit to PF06123, Inner membrane protein CreD, score 9.3e-159 216591027192 6 probable transmembrane helices predicted for BCAM1996 by TMHMM2.0 at aa 5-27, 312-329, 336-358, 363-385, 392-411 and 416-435 216591027193 sensory histidine kinase CreC; Provisional; Region: PRK11100 216591027194 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591027195 dimerization interface [polypeptide binding]; other site 216591027196 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591027197 dimer interface [polypeptide binding]; other site 216591027198 phosphorylation site [posttranslational modification] 216591027199 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591027200 ATP binding site [chemical binding]; other site 216591027201 Mg2+ binding site [ion binding]; other site 216591027202 G-X-G motif; other site 216591027203 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 9e-32 216591027204 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.2e-14 216591027205 HMMPfam hit to PF00672, HAMP domain, score 9.3e-10 216591027206 2 probable transmembrane helices predicted for BCAM1997 by TMHMM2.0 at aa 5-27 and 186-208 216591027207 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027208 DNA-binding response regulator CreB; Provisional; Region: PRK11083 216591027209 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591027210 active site 216591027211 phosphorylation site [posttranslational modification] 216591027212 intermolecular recognition site; other site 216591027213 dimerization interface [polypeptide binding]; other site 216591027214 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591027215 DNA binding site [nucleotide binding] 216591027216 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 2.1e-26 216591027217 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.8e-37 216591027218 short chain dehydrogenase; Provisional; Region: PRK12828 216591027219 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591027220 NAD(P) binding site [chemical binding]; other site 216591027221 active site 216591027222 HMMPfam hit to PF00106, short chain dehydrogenase, score 6.6e-24 216591027223 PS00061 Short-chain dehydrogenases/reductases family signature. 216591027224 1 probable transmembrane helix predicted for BCAM1999 by TMHMM2.0 at aa 7-29 216591027225 dihydrodipicolinate reductase; Region: dapB_plant; TIGR02130 216591027226 3-ketoacyl-(acyl-carrier-protein) reductase; Reviewed; Region: PRK12826 216591027227 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591027228 NAD(P) binding site [chemical binding]; other site 216591027229 active site 216591027230 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.001 216591027231 HMMPfam hit to PF00106, short chain dehydrogenase, score 7e-29 216591027232 PS00061 Short-chain dehydrogenases/reductases family signature. 216591027233 Molybdenum cofactor biosynthesis protein F; Region: MoaF; pfam10703 216591027234 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 216591027235 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591027236 HMMPfam hit to PF02311, AraC-like ligand binding domain, score 1.3e-22 216591027237 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 0.00042 216591027238 Predicted helix-turn-helix motif with score 1464.000, SD 4.17 at aa 180-201, sequence VSLAELADLSGVSRFQLLRGFA 216591027239 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 4.3e-08 216591027240 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 216591027241 EamA-like transporter family; Region: EamA; pfam00892 216591027242 EamA-like transporter family; Region: EamA; pfam00892 216591027243 10 probable transmembrane helices predicted for BCAM2004 by TMHMM2.0 at aa 7-29, 33-55, 68-90, 100-117, 126-148, 153-173, 180-202, 212-234, 247-266 and 270-289 216591027244 HMMPfam hit to PF08449, UAA transporter family, score 0.00043 216591027245 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.3e-15 216591027246 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.2e-19 216591027247 3 probable transmembrane helices predicted for BCAM2005 by TMHMM2.0 at aa 59-81, 85-107 and 137-156 216591027248 Predicted small secreted protein [Function unknown]; Region: COG5510 216591027249 HMMPfam hit to PF08085, Entericidin EcnA/B family, score 2.1e-17 216591027250 1 probable transmembrane helix predicted for BCAM2005A by TMHMM2.0 at aa 4-26 216591027251 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027252 aspartate carbamoyltransferase; Provisional; Region: PRK11891 216591027253 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 216591027254 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 216591027255 Predicted helix-turn-helix motif with score 1325.000, SD 3.70 at aa 18-39, sequence MTREAFANRIGVSRRALDTWLL 216591027256 HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, ca, score 3.1e-46 216591027257 PS00097 Aspartate and ornithine carbamoyltransferases signature. 216591027258 HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, As, score 1.3e-35 216591027259 This CDS appears to have a frameshift mutation. The CDS does not an appropriate translational stop 216591027260 HMMPfam hit to PF01850, PIN domain, score 2e-18 216591027261 This CDS appears to have a frameshift mutation. 216591027262 Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; Region: Fiu; COG4774 216591027263 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591027264 N-terminal plug; other site 216591027265 ligand-binding site [chemical binding]; other site 216591027266 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.3e-17 216591027267 HMMPfam hit to PF00593, TonB dependent receptor, score 6.6e-32 216591027268 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 216591027269 Sel1-like repeats; Region: SEL1; smart00671 216591027270 Sel1-like repeats; Region: SEL1; smart00671 216591027271 HMMPfam hit to PF08238, Sel1 repeat, score 6.8e-08 216591027272 HMMPfam hit to PF08238, Sel1 repeat, score 2e-06 216591027273 HMMPfam hit to PF08238, Sel1 repeat, score 2.7e-05 216591027274 HMMPfam hit to PF08238, Sel1 repeat, score 0.006 216591027275 Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467 216591027276 HMMPfam hit to PF03171, 2OG-Fe(II) oxygenase superfamily, score 5.3e-10 216591027277 Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604 216591027278 GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182 216591027279 metal-binding site 216591027280 short chain dehydrogenase; Provisional; Region: PRK07060 216591027281 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591027282 NAD(P) binding site [chemical binding]; other site 216591027283 active site 216591027284 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0027 216591027285 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.3e-18 216591027286 PS00061 Short-chain dehydrogenases/reductases family signature. 216591027287 Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070 216591027288 uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_XK_like_1; cd07804 216591027289 N- and C-terminal domain interface [polypeptide binding]; other site 216591027290 putative active site [active] 216591027291 MgATP binding site [chemical binding]; other site 216591027292 catalytic site [active] 216591027293 metal binding site [ion binding]; metal-binding site 216591027294 putative xylulose binding site [chemical binding]; other site 216591027295 putative homodimer interface [polypeptide binding]; other site 216591027296 HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 4.8e-43 216591027297 PS00445 FGGY family of carbohydrate kinases signature 2. 216591027298 HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 3e-61 216591027299 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 216591027300 Alcohol dehydrogenases of the MDR family; Region: Zn_ADH2; cd08256 216591027301 putative NAD(P) binding site [chemical binding]; other site 216591027302 catalytic Zn binding site [ion binding]; other site 216591027303 structural Zn binding site [ion binding]; other site 216591027304 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.1e-30 216591027305 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 1.6e-41 216591027306 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591027307 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591027308 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591027309 TM-ABC transporter signature motif; other site 216591027310 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.7e-67 216591027311 7 probable transmembrane helices predicted for BCAM2016 by TMHMM2.0 at aa 10-32, 44-63, 78-100, 107-129, 156-177, 208-230 and 257-279 216591027312 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 216591027313 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591027314 Walker A/P-loop; other site 216591027315 ATP binding site [chemical binding]; other site 216591027316 Q-loop/lid; other site 216591027317 ABC transporter signature motif; other site 216591027318 Walker B; other site 216591027319 D-loop; other site 216591027320 H-loop/switch region; other site 216591027321 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 216591027322 HMMPfam hit to PF00005, ABC transporter score 1.9e-17 216591027323 PS00211 ABC transporters family signature. 216591027324 HMMPfam hit to PF00005, ABC transporter score 1.9e-58 216591027325 PS00017 ATP/GTP-binding site motif A (P-loop). 216591027326 Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321 216591027327 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 216591027328 putative ligand binding site [chemical binding]; other site 216591027329 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 1.6e-05 216591027330 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 216591027331 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591027332 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591027333 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.6e-09 216591027334 PS00041 Bacterial regulatory proteins, araC family signature. 216591027335 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.4e-05 216591027336 Predicted helix-turn-helix motif with score 1469.000, SD 4.19 at aa 197-218, sequence LRESDLAQLTGQSVSAFSRAFH 216591027337 2-dehydropantoate 2-reductase; Provisional; Region: PRK12921 216591027338 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 216591027339 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 216591027340 HMMPfam hit to PF08546, Ketopantoate reductase PanE/ApbA C terminal, score 1.8e-23 216591027341 HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 1.3e-51 216591027342 Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049 216591027343 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 216591027344 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591027345 dimer interface [polypeptide binding]; other site 216591027346 putative CheW interface [polypeptide binding]; other site 216591027347 2 probable transmembrane helices predicted for BCAM2021 by TMHMM2.0 at aa 10-32 and 187-209 216591027348 HMMPfam hit to PF08269, Cache domain, score 4.3e-38 216591027349 HMMPfam hit to PF00672, HAMP domain, score 9.9e-05 216591027350 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 6.3e-98 216591027351 transcriptional regulator RcsB; Provisional; Region: PRK10840 216591027352 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591027353 DNA binding residues [nucleotide binding] 216591027354 dimerization interface [polypeptide binding]; other site 216591027355 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 7.4e-12 216591027356 HMMPfam hit to PF00072, Response regulator receiver domain, score 3.5e-05 216591027357 1 probable transmembrane helix predicted for BCAM2024 by TMHMM2.0 at aa 103-125 216591027358 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 216591027359 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591027360 Walker A motif; other site 216591027361 ATP binding site [chemical binding]; other site 216591027362 Walker B motif; other site 216591027363 arginine finger; other site 216591027364 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 216591027365 DNA-binding interface [nucleotide binding]; DNA binding site 216591027366 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 1.1e-06 216591027367 Predicted helix-turn-helix motif with score 1458.000, SD 4.15 at aa 446-467, sequence HQHADVAAELGISRATLYRLMI 216591027368 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591027369 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 1.3e-136 216591027370 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591027371 PS00017 ATP/GTP-binding site motif A (P-loop). 216591027372 1 probable transmembrane helix predicted for BCAM2031 by TMHMM2.0 at aa 4-26 216591027373 UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230 216591027374 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 216591027375 NAD binding site [chemical binding]; other site 216591027376 putative substrate binding site 2 [chemical binding]; other site 216591027377 putative substrate binding site 1 [chemical binding]; other site 216591027378 active site 216591027379 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 1.7e-52 216591027380 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 0.0003 216591027381 HMMPfam hit to PF07993, Male sterility protein, score 2.8e-06 216591027382 UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087 216591027383 UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247 216591027384 NAD binding site [chemical binding]; other site 216591027385 homodimer interface [polypeptide binding]; other site 216591027386 active site 216591027387 substrate binding site [chemical binding]; other site 216591027388 HMMPfam hit to PF04321, RmlD substrate binding domain, score 6.2e-06 216591027389 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 3.7e-69 216591027390 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.0003 216591027391 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.6e-05 216591027392 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 5.8e-09 216591027393 HMMPfam hit to PF07993, Male sterility protein, score 6.8e-05 216591027394 Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004 216591027395 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210 216591027396 UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984 216591027397 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720 216591027398 HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 5e-86 216591027399 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 0.00085 216591027400 HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 1.6e-48 216591027401 HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 5.3e-31 216591027402 Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215 216591027403 CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421 216591027404 DXD motif; other site 216591027405 Beta-mannanase [Carbohydrate transport and metabolism]; Region: ManB; COG4124 216591027406 8 probable transmembrane helices predicted for BCAM2035 by TMHMM2.0 at aa 49-71, 84-103, 381-403, 415-437, 457-476, 496-518, 528-547 and 568-590 216591027407 AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719 216591027408 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591027409 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591027410 PS00041 Bacterial regulatory proteins, araC family signature. 216591027411 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.6e-09 216591027412 Predicted helix-turn-helix motif with score 1710.000, SD 5.01 at aa 215-236, sequence MRVESLAQAVNMSVSSLHHHFK 216591027413 HMMPfam hit to PF06719, AraC-type transcriptional regulator N-termin, score 1.3e-57 216591027414 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080 216591027415 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591027416 catalytic loop [active] 216591027417 iron binding site [ion binding]; other site 216591027418 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 216591027419 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 4.6e-10 216591027420 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591027421 HMMPfam hit to PF01799, [2Fe-2S] binding domain, score 4.1e-36 216591027422 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591027423 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 216591027424 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 216591027425 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591027426 HMMPfam hit to PF02738, Aldehyde oxidase and xanthine dehydroge, score 2.7e-09 216591027427 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591027428 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591027429 DNA binding site [nucleotide binding] 216591027430 HMMPfam hit to PF00486, Transcriptional regulatory protein, C ter, score 1.3e-16 216591027431 Surface presentation of antigens (SPOA); Region: SpoA; cl00819 216591027432 Surface presentation of antigens (SPOA); Region: SpoA; pfam01052 216591027433 HMMPfam hit to PF01052, Surface presentation of antigens (SPOA) prot, score 0.012 216591027434 HMMPfam hit to PF01052, Surface presentation of antigens (SPOA) prot, score 1.1e-11 216591027435 type III secretion system protein YscR; Provisional; Region: PRK12797 216591027436 4 probable transmembrane helices predicted for BCAM2041 by TMHMM2.0 at aa 7-29, 49-71, 161-183 and 198-220 216591027437 HMMPfam hit to PF00813, FliP family, score 1.4e-106 216591027438 PS00043 Bacterial regulatory proteins, gntR family signature. 216591027439 PS01061 Flagella transport protein fliP family signature 2. 216591027440 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591027441 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591027442 catalytic residue [active] 216591027443 1 probable transmembrane helix predicted for BCAM2042 by TMHMM2.0 at aa 9-31 216591027444 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027445 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 1.8e-15 216591027446 CDS contains a frameshift around codon 3666. Similar to Burkholderia multivorans hypothetical protein UniProt:Q6H253 (EMBL:AY380558 (3953 aa) fasta scores: E()=0, 56.957% id in 3989 aa 216591027447 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591027448 exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108 216591027449 Glutamine amidotransferases class-II (GATase) asparagine synthase_B type. Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a glutaminase domain and a...; Region: AsnB; cd00712 216591027450 active site 216591027451 dimer interface [polypeptide binding]; other site 216591027452 The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the...; Region: Asn_Synthase_B_C; cd01991 216591027453 Ligand Binding Site [chemical binding]; other site 216591027454 Molecular Tunnel; other site 216591027455 The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the...; Region: Asn_Synthase_B_C; cd01991 216591027456 HMMPfam hit to PF00733, Asparagine synthase, score 1e-126 216591027457 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 1.2e-09 216591027458 flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702 216591027459 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822 216591027460 HMMPfam hit to PF01312, FlhB HrpN YscU SpaS Family, score 1.3e-64 216591027461 4 probable transmembrane helices predicted for BCAM2045 by TMHMM2.0 at aa 33-55, 90-112, 137-159 and 174-196 216591027462 Bacterial export proteins, family 1; Region: Bac_export_1; cl00734 216591027463 HMMPfam hit to PF01311, Bacterial export proteins, family, score 5.1e-55 216591027464 6 probable transmembrane helices predicted for BCAM2046 by TMHMM2.0 at aa 12-34, 49-71, 83-105, 128-150, 191-213 and 228-250 216591027465 Flagellar biosynthesis/type III secretory pathway ATPase [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliI; COG1157 216591027466 Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136 216591027467 Walker A motif/ATP binding site; other site 216591027468 Walker B motif; other site 216591027469 HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 5.2e-122 216591027470 PS00152 ATP synthase alpha and beta subunits signature. 216591027471 PS00017 ATP/GTP-binding site motif A (P-loop). 216591027472 HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 1e-05 216591027473 type III secretion system protein; Reviewed; Region: PRK06937 216591027474 Flagellar assembly protein FliH; Region: FliH; pfam02108 216591027475 YOP proteins translocation protein K (YscK); Region: YscK; pfam06578 216591027476 type III secretion apparatus lipoprotein, YscJ/HrcJ family; Region: III_secr_YscJ; TIGR02544 216591027477 1 probable transmembrane helix predicted for BCAM2051 by TMHMM2.0 at aa 229-251 216591027478 HMMPfam hit to PF01514, Secretory protein of YscJ/FliF family, score 2e-71 216591027479 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027480 type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500 216591027481 FHA domain; Region: FHA; pfam00498 216591027482 Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356 216591027483 2 probable transmembrane helices predicted for BCAM2054 by TMHMM2.0 at aa 15-37 and 167-189 216591027484 HMMPfam hit to PF00498, FHA domain, score 1.2e-10 216591027485 type III secretion outer membrane pore, YscC/HrcC family; Region: type_III_yscC; TIGR02516 216591027486 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 216591027487 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 216591027488 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 216591027489 HMMPfam hit to PF00263, Bacterial type II and III secretion system, score 1e-53 216591027490 PS00875 Bacterial type II secretion system protein D signature. 216591027491 HMMPfam hit to PF03958, Bacterial type II/III secretion system sho, score 2.1e-10 216591027492 HMMPfam hit to PF03958, Bacterial type II/III secretion system sho, score 2.5e-09 216591027493 1 probable transmembrane helix predicted for BCAM2055 by TMHMM2.0 at aa 19-41 216591027494 Bacterial export proteins, family 3; Region: Bac_export_3; cl00867 216591027495 HMMPfam hit to PF01313, Bacterial export proteins, family, score 4e-23 216591027496 2 probable transmembrane helices predicted for BCAM2056 by TMHMM2.0 at aa 15-37 and 49-71 216591027497 Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; cl07980 216591027498 FHIPEP family; Region: FHIPEP; pfam00771 216591027499 HMMPfam hit to PF00771, FHIPEP family, score 3.1e-251 216591027500 7 probable transmembrane helices predicted for BCAM2057 by TMHMM2.0 at aa 35-57, 62-84, 89-111, 126-148, 218-240, 260-282 and 303-325 216591027501 PS00994 Bacterial export FHIPEP family signature. 216591027502 Autoinducer binding domain; Region: Autoind_bind; pfam03472 216591027503 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315 216591027504 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 0.00052 216591027505 Autoinducer binding domain; Region: Autoind_bind; pfam03472 216591027506 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591027507 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591027508 DNA binding residues [nucleotide binding] 216591027509 dimerization interface [polypeptide binding]; other site 216591027510 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 5.5e-08 216591027511 Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914 216591027512 Natural resistance-associated macrophage protein; Region: Nramp; pfam01566 216591027513 13 probable transmembrane helices predicted for BCAM2060 by TMHMM2.0 at aa 46-65, 80-99, 126-148, 153-175, 188-210, 230-249, 271-293, 324-346, 367-389, 394-416, 429-451, 461-483 and 525-547 216591027514 HMMPfam hit to PF01566, Natural resistance-associated macrophage pro, score 2.4e-06 216591027515 Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966 216591027516 HMMPfam hit to PF04966, Carbohydrate-selective porin, OprB family, score 8.7e-136 216591027517 PS00678 Trp-Asp (WD) repeats signature. 216591027518 Trehalase; Region: Trehalase; cl17346 216591027519 Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626 216591027520 HMMPfam hit to PF01204, Trehalase, score 1.6e-241 216591027521 PS00928 Trehalase signature 2. 216591027522 PS00927 Trehalase signature 1. 216591027523 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027524 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591027525 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591027526 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.5e-13 216591027527 Predicted helix-turn-helix motif with score 1382.000, SD 3.89 at aa 44-65, sequence YTTNAVAALAGVSIGSLYQYFP 216591027528 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591027529 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591027530 putative substrate translocation pore; other site 216591027531 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027532 14 probable transmembrane helices predicted for BCAM2066 by TMHMM2.0 at aa 13-35, 55-74, 81-103, 107-129, 142-164, 168-187, 200-222, 232-251, 272-294, 299-318, 330-352, 356-378, 399-421 and 436-453 216591027533 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.1e-49 216591027534 Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230 216591027535 Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255 216591027536 catalytic residue [active] 216591027537 putative FPP diphosphate binding site; other site 216591027538 putative FPP binding hydrophobic cleft; other site 216591027539 dimer interface [polypeptide binding]; other site 216591027540 putative IPP diphosphate binding site; other site 216591027541 HMMPfam hit to PF01255, Putative undecaprenyl diphosphate synthase, score 1.6e-75 216591027542 PS01066 Undecaprenyl pyrophosphate synthetase family signature. 216591027543 Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210 216591027544 substrate binding pocket [chemical binding]; other site 216591027545 substrate-Mg2+ binding site; other site 216591027546 aspartate-rich region 1; other site 216591027547 aspartate-rich region 2; other site 216591027548 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214 216591027549 Protein of unknown function (DUF1006); Region: DUF1006; pfam06224 216591027550 HMMPfam hit to PF06224, Protein of unknown function (DUF1006), score 1.7e-160 216591027551 Protein of unknown function (DUF1653); Region: DUF1653; pfam07866 216591027552 HMMPfam hit to PF07866, Protein of unknown function (DUF1653), score 3.4e-14 216591027553 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 216591027554 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591027555 Coenzyme A binding pocket [chemical binding]; other site 216591027556 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.3e-12 216591027557 Predicted phosphatases [General function prediction only]; Region: Gph; COG0546 216591027558 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.3e-22 216591027559 Domain of unknown function (DUF4142); Region: DUF4142; pfam13628 216591027560 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 216591027561 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591027562 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.1e-06 216591027563 DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013 216591027564 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591027565 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591027566 dimerization interface [polypeptide binding]; other site 216591027567 HMMPfam hit to PF03466, LysR substrate binding domain, score 1e-38 216591027568 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 7.5e-19 216591027569 PS00044 Bacterial regulatory proteins, lysR family signature. 216591027570 Predicted helix-turn-helix motif with score 1680.000, SD 4.91 at aa 17-38, sequence GSTTRAAEMLYTSQPTISRELA 216591027571 diaminopimelate decarboxylase; Provisional; Region: PRK11165 216591027572 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828 216591027573 active site 216591027574 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 216591027575 substrate binding site [chemical binding]; other site 216591027576 catalytic residues [active] 216591027577 dimer interface [polypeptide binding]; other site 216591027578 HMMPfam hit to PF02784, Pyridoxal-dependent decarboxylase, py, score 3.3e-68 216591027579 PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 216591027580 PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 216591027581 HMMPfam hit to PF00278, Pyridoxal-dependent decarboxylase, C-, score 2.4e-30 216591027582 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 216591027583 EamA-like transporter family; Region: EamA; pfam00892 216591027584 10 probable transmembrane helices predicted for BCAM2077 by TMHMM2.0 at aa 7-29, 34-56, 68-87, 91-113, 120-139, 144-166, 179-198, 208-230, 237-259 and 264-286 216591027585 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.3e-11 216591027586 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027587 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 5.8e-15 216591027588 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591027589 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591027590 DNA-binding site [nucleotide binding]; DNA binding site 216591027591 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591027592 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591027593 homodimer interface [polypeptide binding]; other site 216591027594 catalytic residue [active] 216591027595 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 3e-17 216591027596 Predicted helix-turn-helix motif with score 1127.000, SD 3.03 at aa 44-65, sequence PSIRMMADALGVSKSTVVDAYE 216591027597 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.9e-17 216591027598 putative nicotinate phosphoribosyltransferase; Provisional; Region: PRK09198 216591027599 pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general; Region: PBEF_like; cd01569 216591027600 active site 216591027601 HMMPfam hit to PF04095, Nicotinate phosphoribosyltransferase (NAPRTa, score 4.8e-101 216591027602 bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase; Provisional; Region: PRK05379 216591027603 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 216591027604 active site 216591027605 nucleotide binding site [chemical binding]; other site 216591027606 HIGH motif; other site 216591027607 KMSKS motif; other site 216591027608 ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051 216591027609 nudix motif; other site 216591027610 HMMPfam hit to PF00293, NUDIX domain, score 3.1e-30 216591027611 PS00893 mutT domain signature. 216591027612 HMMPfam hit to PF01467, Cytidylyltransferase, score 5.3e-11 216591027613 START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643 216591027614 hydrophobic ligand binding site; other site 216591027615 S-adenosylmethionine decarboxylase; Region: AdoMet_dc; cl00687 216591027616 HMMPfam hit to PF02675, S-adenosylmethionine decarboxylase, score 3.1e-41 216591027617 Domain of unknown function (DUF4178); Region: DUF4178; pfam13785 216591027618 Domain of unknown function (DUF4178); Region: DUF4178; pfam13785 216591027619 2 probable transmembrane helices predicted for BCAM2083 by TMHMM2.0 at aa 451-473 and 478-495 216591027620 PS00190 Cytochrome c family heme-binding site signature. 216591027621 A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin. Many of these band 7 domain-containing proteins are lipid raft-associated. Individual...; Region: Band_7_5; cd03408 216591027622 Short C-terminal domain; Region: SHOCT; pfam09851 216591027623 Domain of Unknown Function (DUF350); Region: DUF350; pfam03994 216591027624 Domain of Unknown Function (DUF350); Region: DUF350; pfam03994 216591027625 HMMPfam hit to PF03994, Domain of Unknown Function (DUF350), score 4e-08 216591027626 4 probable transmembrane helices predicted for BCAM2085 by TMHMM2.0 at aa 7-26, 41-63, 68-90 and 105-127 216591027627 HMMPfam hit to PF03994, Domain of Unknown Function (DUF350), score 8.4e-08 216591027628 spermidine synthase; Provisional; Region: PRK03612 216591027629 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591027630 7 probable transmembrane helices predicted for BCAM2086 by TMHMM2.0 at aa 7-26, 36-58, 75-97, 101-123, 136-158, 163-185 and 197-214 216591027631 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027632 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027633 HMMPfam hit to PF01564, Spermine/spermidine synthase, score 4.7e-49 216591027634 PS01330 Spermidine/spermine synthases family signature. 216591027635 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 216591027636 Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593 216591027637 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027638 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.0014 216591027639 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027640 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860 216591027641 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 216591027642 active site 216591027643 metal binding site [ion binding]; metal-binding site 216591027644 HMMPfam hit to PF01520, N-acetylmuramoyl-L-alanine amidase, score 2.5e-13 216591027645 Protein of unknown function (DUF1311); Region: DUF1311; pfam07007 216591027646 1 probable transmembrane helix predicted for BCAM2089 by TMHMM2.0 at aa 30-49 216591027647 HMMPfam hit to PF07007, Protein of unknown function (DUF1311), score 1.3e-06 216591027648 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591027649 Coenzyme A binding pocket [chemical binding]; other site 216591027650 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.9e-16 216591027651 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591027652 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591027653 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591027654 dimerization interface [polypeptide binding]; other site 216591027655 HMMPfam hit to PF03466, LysR substrate binding domain, score 7.5e-36 216591027656 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.5e-19 216591027657 PS00044 Bacterial regulatory proteins, lysR family signature. 216591027658 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654 216591027659 hypothetical protein; Provisional; Region: PRK07236 216591027660 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00015 216591027661 HMMPfam hit to PF01494, FAD binding domain, score 6.1e-08 216591027662 Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174 216591027663 Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120 216591027664 HMMPfam hit to PF00120, Glutamine synthetase, catalytic domain, score 1.1e-67 216591027665 PS00181 Glutamine synthetase putative ATP-binding region signature. 216591027666 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591027667 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591027668 non-specific DNA binding site [nucleotide binding]; other site 216591027669 salt bridge; other site 216591027670 sequence-specific DNA binding site [nucleotide binding]; other site 216591027671 Cupin domain; Region: Cupin_2; pfam07883 216591027672 HMMPfam hit to PF07883, Cupin domain, score 2.5e-16 216591027673 HMMPfam hit to PF01381, Helix-turn-helix, score 3.8e-12 216591027674 Predicted helix-turn-helix motif with score 1346.000, SD 3.77 at aa 23-44, sequence VTLNDLAERIGRSVGFLSQVER 216591027675 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591027676 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591027677 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.4e-89 216591027678 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591027679 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 216591027680 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591027681 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 216591027682 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591027683 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591027684 HMMPfam hit to PF02738, Aldehyde oxidase and xanthine dehydroge, score 1.2e-08 216591027685 HMMPfam hit to PF01315, Aldehyde oxidase and xanthine dehydroge, score 0.0039 216591027686 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080 216591027687 Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868 216591027688 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 216591027689 HMMPfam hit to PF01799, [2Fe-2S] binding domain, score 1.4e-31 216591027690 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 4.5e-07 216591027691 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591027692 Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141 216591027693 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 216591027694 potential catalytic triad [active] 216591027695 conserved cys residue [active] 216591027696 HMMPfam hit to PF01965, DJ-1/PfpI family, score 2.7e-18 216591027697 Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600 216591027698 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 216591027699 DNA binding residues [nucleotide binding] 216591027700 HMMPfam hit to PF00376, MerR family regulatory protein, score 5.6e-12 216591027701 PS00552 Bacterial regulatory proteins, merR family signature. 216591027702 Predicted helix-turn-helix motif with score 1911.000, SD 5.70 at aa 1-22, sequence MKIGDLAERTGLTPSRIRFYER 216591027703 transposase/IS protein; Provisional; Region: PRK09183 216591027704 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591027705 Walker A motif; other site 216591027706 ATP binding site [chemical binding]; other site 216591027707 Walker B motif; other site 216591027708 HMMPfam hit to PF01695, IstB-like ATP binding protein, score 9.6e-88 216591027709 PS00017 ATP/GTP-binding site motif A (P-loop). 216591027710 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584 216591027711 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 216591027712 DNA-binding interface [nucleotide binding]; DNA binding site 216591027713 Integrase core domain; Region: rve; pfam00665 216591027714 HMMPfam hit to PF00665, Integrase core domain, score 2.7e-25 216591027715 HMMPfam hit to PF02796, Helix-turn-helix domain of resolvase, score 0.0028 216591027716 Predicted helix-turn-helix motif with score 2020.000, SD 6.07 at aa 18-39, sequence VSEREIARRLGISRNTVARYLS 216591027717 Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600 216591027718 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 216591027719 DNA binding residues [nucleotide binding] 216591027720 Predicted helix-turn-helix motif with score 1462.000, SD 4.17 at aa 51-72, sequence LGLISIAQQAGFTLEQIRQLLP 216591027721 HMMPfam hit to PF00376, MerR family regulatory protein, score 2.8e-11 216591027722 PS00552 Bacterial regulatory proteins, merR family signature. 216591027723 Predicted helix-turn-helix motif with score 1462.000, SD 4.17 at aa 5-26, sequence VKIGELAKRSGLTASRIRFYEA 216591027724 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591027725 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591027726 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 2e-35 216591027727 catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061 216591027728 N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649 216591027729 dimer interface [polypeptide binding]; other site 216591027730 active site 216591027731 heme binding site [chemical binding]; other site 216591027732 C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200 216591027733 HMMPfam hit to PF00141, Peroxidase, score 9.4e-82 216591027734 PS00436 Peroxidases active site signature. 216591027735 PS00435 Peroxidases proximal heme-ligand signature. 216591027736 PS00017 ATP/GTP-binding site motif A (P-loop). 216591027737 HMMPfam hit to PF00141, Peroxidase, score 1.6e-119 216591027738 putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824 216591027739 PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276 216591027740 NAD(P) binding site [chemical binding]; other site 216591027741 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 4.1e-21 216591027742 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.2e-34 216591027743 PS00962 Ribosomal protein S2 signature 1. 216591027744 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591027745 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591027746 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 216591027747 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 2.9e-34 216591027748 Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141 216591027749 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 216591027750 potential catalytic triad [active] 216591027751 conserved cys residue [active] 216591027752 HMMPfam hit to PF01965, DJ-1/PfpI family, score 2.9e-12 216591027753 1 probable transmembrane helix predicted for BCAM2110 by TMHMM2.0 at aa 5-27 216591027754 putative catalase (fragment);Similar to an internal region of Pseudomonas aeruginosa KatB catalase precursor (paraquat-inducible catalase isozyme b). UniProt:Q59635 (EMBL:AE004875) (513 aa) fasta scores: E()=3e-12, 49.000% id in 100 aa 216591027755 atypical (a) SDRs, subgroup 3; Region: SDR_a3; cd05229 216591027756 NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370 216591027757 putative NAD(P) binding site [chemical binding]; other site 216591027758 putative active site [active] 216591027759 HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.00018 216591027760 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 1.2e-07 216591027761 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 0.00056 216591027762 putative peptidase/dipeptidase (fragment);Similar to C-terminus of Mycobacterium bovis probable dipeptidase PepE. UniProt:P65811 (EMBL:BX248341) (375 aa) fasta scores: E()=6.3e-06, 36.585% id in 82 aa, and to C-terminus of /NCIB 9086/R18194)) peptidase m24. UniProt:Q391R1 (EMBL:CP000152) (388 aa) fasta scores: E()=7.5e-24, 76.404% id in 89 aa 216591027763 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591027764 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591027765 putative substrate translocation pore; other site 216591027766 HMMPfam hit to PF00083, Sugar (and other) transporter score 3.4e-07 216591027767 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.7e-15 216591027768 12 probable transmembrane helices predicted for BCAM2113 by TMHMM2.0 at aa 88-107, 112-134, 147-169, 179-201, 213-235, 245-264, 303-325, 335-357, 364-383, 393-415, 428-450 and 455-477 216591027769 PS00217 Sugar transport proteins signature 2. 216591027770 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591027771 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591027772 active site 216591027773 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 0.002 216591027774 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 2.1e-21 216591027775 Flavin Reductases; Region: FlaRed; cl00801 216591027776 HMMPfam hit to PF01613, Flavin reductase like domain, score 8.6e-47 216591027777 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591027778 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591027779 The C-terminal substrate binding domain of LysR-type transcriptional regulators that are involved in the catabolism of dinitrotoluene, naphthalene and gamma-hexachlorohexane; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_NahR_LinR_like; cd08459 216591027780 substrate binding pocket [chemical binding]; other site 216591027781 dimerization interface [polypeptide binding]; other site 216591027782 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.4e-20 216591027783 Predicted helix-turn-helix motif with score 1701.000, SD 4.98 at aa 36-57, sequence RSLTAAGDRLELTQPAVSHALR 216591027784 PS00044 Bacterial regulatory proteins, lysR family signature. 216591027785 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.7e-30 216591027786 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591027787 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591027788 The C-terminal substrate binding domain of LysR-type transcriptional regulators that are involved in the catabolism of dinitrotoluene, naphthalene and gamma-hexachlorohexane; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_NahR_LinR_like; cd08459 216591027789 substrate binding pocket [chemical binding]; other site 216591027790 dimerization interface [polypeptide binding]; other site 216591027791 HMMPfam hit to PF03466, LysR substrate binding domain, score 2e-19 216591027792 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5e-21 216591027793 PS00044 Bacterial regulatory proteins, lysR family signature. 216591027794 Predicted helix-turn-helix motif with score 1264.000, SD 3.49 at aa 22-43, sequence HSLTRAGERLALSQPAVSYSLG 216591027795 Carboxylesterase family; Region: COesterase; pfam00135 216591027796 Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312 216591027797 substrate binding pocket [chemical binding]; other site 216591027798 catalytic triad [active] 216591027799 HMMPfam hit to PF00135, Carboxylesterase, score 4.2e-126 216591027800 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027801 PS00941 Carboxylesterases type-B signature 2. 216591027802 PS00122 Carboxylesterases type-B serine active site. 216591027803 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 216591027804 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 1.2e-18 216591027805 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195 216591027806 4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943 216591027807 active site 216591027808 catalytic residues [active] 216591027809 metal binding site [ion binding]; metal-binding site 216591027810 DmpG-like communication domain; Region: DmpG_comm; pfam07836 216591027811 HMMPfam hit to PF07836, DmpG-like communication domain, score 1.7e-42 216591027812 HMMPfam hit to PF00682, HMGL-like, score 4.9e-105 216591027813 acetaldehyde dehydrogenase; Validated; Region: PRK08300 216591027814 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 216591027815 Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290 216591027816 HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindin, score 1.4e-27 216591027817 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 216591027818 HMMPfam hit to PF01689, Hydratase/decarboxylase, score 1.3e-59 216591027819 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 216591027820 HMMPfam hit to PF01689, Hydratase/decarboxylase, score 2.7e-111 216591027821 Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331 216591027822 active site 216591027823 ribulose/triose binding site [chemical binding]; other site 216591027824 phosphate binding site [ion binding]; other site 216591027825 substrate (anthranilate) binding pocket [chemical binding]; other site 216591027826 product (indole) binding pocket [chemical binding]; other site 216591027827 HMMPfam hit to PF00218, Indole-3-glycerol phosphate synthase, score 3.2e-111 216591027828 PS00614 Indole-3-glycerol phosphate synthase signature. 216591027829 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591027830 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591027831 eyelet of channel; other site 216591027832 trimer interface [polypeptide binding]; other site 216591027833 HMMPfam hit to PF00267, Gram-negative porin, score 4.3e-06 216591027834 Dienelactone hydrolase family; Region: DLH; pfam01738 216591027835 Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109 216591027836 HMMPfam hit to PF07366, SnoaL-like polyketide cyclase, score 0.0043 216591027837 HMMPfam hit to PF01738, Dienelactone hydrolase family, score 4.6e-65 216591027838 short chain dehydrogenase; Validated; Region: PRK08264 216591027839 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591027840 NAD(P) binding site [chemical binding]; other site 216591027841 active site 216591027842 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0025 216591027843 HMMPfam hit to PF00106, short chain dehydrogenase, score 3e-13 216591027844 Amidohydrolase; Region: Amidohydro_2; pfam04909 216591027845 HMMPfam hit to PF04909, Amidohydrolase, score 5.6e-43 216591027846 3-hydroxyanthranilate 3,4-dioxygenase; Provisional; Region: PRK13264 216591027847 HMMPfam hit to PF06052, 3-hydroxyanthranilic acid dioxygenase, score 5.1e-48 216591027848 HMMPfam hit to PF07883, Cupin domain, score 0.00043 216591027849 PS00030 Eukaryotic putative RNA-binding region RNP-1 signature. 216591027850 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 216591027851 homotrimer interaction site [polypeptide binding]; other site 216591027852 putative active site [active] 216591027853 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 5.5e-30 216591027854 2-hydroxymuconic semialdehyde dehydrogenase; Region: OH_muco_semi_DH; TIGR03216 216591027855 Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093 216591027856 NAD binding site [chemical binding]; other site 216591027857 catalytic residues [active] 216591027858 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.5e-218 216591027859 PS00070 Aldehyde dehydrogenases cysteine active site. 216591027860 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591027861 Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]; Region: COG1545 216591027862 Rubredoxin-like zinc ribbon domain (DUF35_N); Region: DUF35_N; pfam12172 216591027863 thiolase; Provisional; Region: PRK06158 216591027864 Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal...; Region: SCP-x_thiolase; cd00829 216591027865 active site 216591027866 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591027867 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591027868 putative substrate translocation pore; other site 216591027869 HMMPfam hit to PF00083, Sugar (and other) transporter score 3.9e-20 216591027870 12 probable transmembrane helices predicted for BCAM2135 by TMHMM2.0 at aa 20-42, 57-79, 92-114, 124-146, 158-180, 190-212, 253-275, 279-301, 310-329, 334-353, 374-396 and 401-423 216591027871 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2e-19 216591027872 crotonobetaine/carnitine-CoA ligase; Provisional; Region: PRK06155 216591027873 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591027874 Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934 216591027875 acyl-activating enzyme (AAE) consensus motif; other site 216591027876 putative AMP binding site [chemical binding]; other site 216591027877 putative active site [active] 216591027878 putative CoA binding site [chemical binding]; other site 216591027879 HMMPfam hit to PF00501, AMP-binding enzyme, score 3e-89 216591027880 PS00455 Putative AMP-binding domain signature. 216591027881 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591027882 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591027883 The C-terminal substrate binding domain of LysR-type transcriptional regulators that are involved in the catabolism of dinitrotoluene, naphthalene and gamma-hexachlorohexane; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_NahR_LinR_like; cd08459 216591027884 substrate binding pocket [chemical binding]; other site 216591027885 dimerization interface [polypeptide binding]; other site 216591027886 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.7e-21 216591027887 Predicted helix-turn-helix motif with score 1917.000, SD 5.72 at aa 22-43, sequence RSLTRAAQRLHLSQPTISYSLG 216591027888 PS00044 Bacterial regulatory proteins, lysR family signature. 216591027889 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.7e-16 216591027890 Protein of unknown function (DUF2945); Region: DUF2945; pfam11160 216591027891 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591027892 Protein of unknown function, DUF488; Region: DUF488; pfam04343 216591027893 HMMPfam hit to PF06571, Protein of unknown function (DUF1130), score 4.8e-65 216591027894 type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843 216591027895 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591027896 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591027897 PS00543 HlyD family secretion proteins signature. 216591027898 HMMPfam hit to PF00529, HlyD family secretion protein, score 8.6e-10 216591027899 1 probable transmembrane helix predicted for BCAM2140 by TMHMM2.0 at aa 2-19 216591027900 type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375 216591027901 Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296 216591027902 putative active site [active] 216591027903 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 216591027904 ATP-binding cassette domain of bacteriocin exporters, subfamily C; Region: ABCC_bacteriocin_exporters; cd03245 216591027905 Walker A/P-loop; other site 216591027906 ATP binding site [chemical binding]; other site 216591027907 Q-loop/lid; other site 216591027908 ABC transporter signature motif; other site 216591027909 Walker B; other site 216591027910 D-loop; other site 216591027911 H-loop/switch region; other site 216591027912 HMMPfam hit to PF00005, ABC transporter score 4.8e-53 216591027913 PS00211 ABC transporters family signature. 216591027914 PS00017 ATP/GTP-binding site motif A (P-loop). 216591027915 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 2.6e-07 216591027916 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591027917 3 probable transmembrane helices predicted for BCAM2141 by TMHMM2.0 at aa 170-192, 202-221 and 291-313 216591027918 type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844 216591027919 HMMPfam hit to PF02321, Outer membrane efflux protein, score 6.6e-16 216591027920 HMMPfam hit to PF02321, Outer membrane efflux protein, score 6.6e-26 216591027921 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027922 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027923 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027924 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027925 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027926 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027927 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027928 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027929 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027930 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027931 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027932 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027933 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027934 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027935 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027936 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 216591027937 Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199 216591027938 type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661 216591027939 HMMPfam hit to PF00353, Hemolysin-type calcium-binding repeat, score 0.00015 216591027940 PS00330 Hemolysin-type calcium-binding region signature. 216591027941 HMMPfam hit to PF00353, Hemolysin-type calcium-binding repeat, score 2.1e-05 216591027942 HMMPfam hit to PF00353, Hemolysin-type calcium-binding repeat, score 0.01 216591027943 PS00330 Hemolysin-type calcium-binding region signature. 216591027944 HMMPfam hit to PF00353, Hemolysin-type calcium-binding repeat, score 0.0099 216591027945 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 216591027946 7 probable transmembrane helices predicted for BCAM2144 by TMHMM2.0 at aa 2-24, 29-51, 71-90, 100-118, 139-161, 195-217 and 224-242 216591027947 HMMPfam hit to PF01925, Domain of unknown function DUF81, score 2.4e-06 216591027948 Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113 216591027949 Spore germination protein; Region: Spore_permease; cl17796 216591027950 HMMPfam hit to PF03845, Spore germination protein, score 0.0012 216591027951 HMMPfam hit to PF00324, Amino acid permease, score 2.2e-101 216591027952 12 probable transmembrane helices predicted for BCAM2145 by TMHMM2.0 at aa 17-39, 43-62, 74-96, 116-138, 151-173, 188-210, 237-259, 279-301, 327-349, 354-376, 397-419 and 424-443 216591027953 PS00218 Amino acid permeases signature. 216591027954 NnrU protein; Region: NnrU; pfam07298 216591027955 HMMPfam hit to PF07298, NnrU protein, score 2.2e-41 216591027956 5 probable transmembrane helices predicted for BCAM2146 by TMHMM2.0 at aa 2-21, 36-58, 71-93, 113-135 and 156-178 216591027957 TfoX N-terminal domain; Region: TfoX_N; pfam04993 216591027958 HMMPfam hit to PF04993, TfoX N-terminal domain, score 4.9e-17 216591027959 putative dehydrogenase; Provisional; Region: PRK10098 216591027960 HMMPfam hit to PF02615, Malate/L-lactate dehydrogenase, score 1.3e-118 216591027961 hypothetical protein; Provisional; Region: PRK07907 216591027962 Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_5; cd05682 216591027963 metal binding site [ion binding]; metal-binding site 216591027964 putative dimer interface [polypeptide binding]; other site 216591027965 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 5.2e-16 216591027966 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 2e-14 216591027967 transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393 216591027968 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 216591027969 conserved cys residue [active] 216591027970 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591027971 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.3e-06 216591027972 PS00041 Bacterial regulatory proteins, araC family signature. 216591027973 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 6.8e-07 216591027974 PS00041 Bacterial regulatory proteins, araC family signature. 216591027975 Predicted helix-turn-helix motif with score 1482.000, SD 4.23 at aa 229-250, sequence HTLASLAAQAAMSTRTLQRQFS 216591027976 HMMPfam hit to PF01965, DJ-1/PfpI family, score 3.7e-23 216591027977 Member of the Rhodanese Homology Domain superfamily. This CD includes the putative rhodanese-like protein, Psp2, of Yersinia pestis biovar Medievalis and other similar uncharacterized proteins; Region: RHOD_PspE2; cd01521 216591027978 active site residue [active] 216591027979 HMMPfam hit to PF00581, Rhodanese-like domain, score 1.6e-09 216591027980 PS00380 Rhodanese signature 1. 216591027981 Superinfection immunity protein; Region: Imm_superinfect; pfam14373 216591027982 2 probable transmembrane helices predicted for BCAM2152 by TMHMM2.0 at aa 4-26 and 35-57 216591027983 Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124 216591027984 Cytochrome P450; Region: p450; cl12078 216591027985 PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 216591027986 Uncharacterized small protein (DUF2158); Region: DUF2158; pfam09926 216591027987 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 216591027988 Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714 216591027989 tetramer interface [polypeptide binding]; other site 216591027990 active site 216591027991 Mg2+/Mn2+ binding site [ion binding]; other site 216591027992 Ankyrin repeats (many copies); Region: Ank_4; pfam13637 216591027993 ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cl02529 216591027994 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591027995 Coenzyme A binding pocket [chemical binding]; other site 216591027996 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.4e-15 216591027997 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 216591027998 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 216591027999 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 216591028000 putative active site [active] 216591028001 HMMPfam hit to PF01380, SIS domain, score 1.4e-11 216591028002 HMMPfam hit to PF01418, Helix-turn-helix domain, rpiR family, score 0.00016 216591028003 Bacterial OB fold (BOF) protein; Region: BOF; cl01196 216591028004 HMMPfam hit to PF04076, Domain unknown function (DUF388), score 4.9e-26 216591028005 1 probable transmembrane helix predicted for BCAM2159 by TMHMM2.0 at aa 7-29 216591028006 DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643 216591028007 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591028008 active site 216591028009 phosphorylation site [posttranslational modification] 216591028010 intermolecular recognition site; other site 216591028011 dimerization interface [polypeptide binding]; other site 216591028012 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591028013 DNA binding site [nucleotide binding] 216591028014 HMMPfam hit to PF00072, Response regulator receiver domain, score 5.9e-37 216591028015 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 4.5e-20 216591028016 sensor protein QseC; Provisional; Region: PRK10337 216591028017 HAMP domain; Region: HAMP; pfam00672 216591028018 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591028019 dimer interface [polypeptide binding]; other site 216591028020 phosphorylation site [posttranslational modification] 216591028021 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591028022 ATP binding site [chemical binding]; other site 216591028023 Mg2+ binding site [ion binding]; other site 216591028024 G-X-G motif; other site 216591028025 1 probable transmembrane helix predicted for BCAM2161 by TMHMM2.0 at aa 20-42 216591028026 HMMPfam hit to PF00672, HAMP domain, score 1.2e-08 216591028027 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 9.5e-14 216591028028 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 6.8e-37 216591028029 Transcriptional regulators [Transcription]; Region: MarR; COG1846 216591028030 MarR family; Region: MarR_2; pfam12802 216591028031 HMMPfam hit to PF01047, MarR family, score 8.7e-07 216591028032 Predicted helix-turn-helix motif with score 1365.000, SD 3.84 at aa 52-73, sequence PNIPQIADTMGITRQAVLKQIN 216591028033 Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992 216591028034 HMMPfam hit to PF03992, Antibiotic biosynthesis monooxygenase, score 7.2e-18 216591028035 Protein of unknown function (DUF805); Region: DUF805; cl01224 216591028036 2 probable transmembrane helices predicted for BCAM2164 by TMHMM2.0 at aa 5-27 and 34-56 216591028037 Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354 216591028038 HMMPfam hit to PF00144, Beta-lactamase, score 6.4e-54 216591028039 PS00146 Beta-lactamase class-A active site. 216591028040 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591028041 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591028042 The C-terminal substrate-binding domain of LysR-type trnascriptional regulator BlaA which involved in control of the beta-lactamase gene expression; contains the type 2 periplasmic binding fold; Region: PBP2_BlaA; cd08487 216591028043 putative dimerization interface [polypeptide binding]; other site 216591028044 putative substrate binding pocket [chemical binding]; other site 216591028045 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.3e-17 216591028046 Predicted helix-turn-helix motif with score 1352.000, SD 3.79 at aa 23-44, sequence LNFTRAGLELSVTQAAVSQQVR 216591028047 PS00044 Bacterial regulatory proteins, lysR family signature. 216591028048 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.9e-48 216591028049 Glycogen debranching enzyme [Carbohydrate transport and metabolism]; Region: GDB1; COG3408 216591028050 Amylo-alpha-1,6-glucosidase; Region: GDE_C; pfam06202 216591028051 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028052 HMMPfam hit to PF06202, Amylo-alpha-1,6-glucosidase, score 2.3e-05 216591028053 Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951 216591028054 Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951 216591028055 Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951 216591028056 outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414 216591028057 Autotransporter beta-domain; Region: Autotransporter; pfam03797 216591028058 HMMPfam hit to PF03797, Autotransporter beta-domain, score 2.9e-37 216591028059 HMMPfam hit to PF05594, Haemagluttinin repeat, score 1.5 216591028060 HMMPfam hit to PF05594, Haemagluttinin repeat, score 4.4 216591028061 HMMPfam hit to PF05594, Haemagluttinin repeat, score 1.4 216591028062 HMMPfam hit to PF02415, no description, score 26 216591028063 HMMPfam hit to PF05594, Haemagluttinin repeat, score 3.5 216591028064 HMMPfam hit to PF05594, Haemagluttinin repeat, score 2.5 216591028065 HMMPfam hit to PF02415, no description, score 53 216591028066 YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259 216591028067 putative active site [active] 216591028068 HMMPfam hit to PF02698, DUF218 domain, score 2.1e-40 216591028069 1 probable transmembrane helix predicted for BCAM2170 by TMHMM2.0 at aa 13-35 216591028070 rod shape-determining protein MreB; Provisional; Region: PRK13930 216591028071 MreB and similar proteins; Region: MreB_like; cd10225 216591028072 nucleotide binding site [chemical binding]; other site 216591028073 Mg binding site [ion binding]; other site 216591028074 putative protofilament interaction site [polypeptide binding]; other site 216591028075 RodZ interaction site [polypeptide binding]; other site 216591028076 HMMPfam hit to PF06723, MreB/Mbl protein, score 3.8e-138 216591028077 Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752 216591028078 Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205 216591028079 active site 216591028080 nucleophile elbow; other site 216591028081 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 216591028082 Surface antigen; Region: Bac_surface_Ag; pfam01103 216591028083 HMMPfam hit to PF01734, Patatin-like phospholipase, score 4.1e-44 216591028084 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 4.5e-05 216591028085 PS00017 ATP/GTP-binding site motif A (P-loop). 216591028086 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 216591028087 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591028088 HMMPfam hit to PF02525, Flavodoxin-like fold, score 9.2e-11 216591028089 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 0.00044 216591028090 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591028091 dimer interface [polypeptide binding]; other site 216591028092 phosphorylation site [posttranslational modification] 216591028093 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591028094 ATP binding site [chemical binding]; other site 216591028095 Mg2+ binding site [ion binding]; other site 216591028096 G-X-G motif; other site 216591028097 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.4e-23 216591028098 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.5e-15 216591028099 2 probable transmembrane helices predicted for BCAM2174 by TMHMM2.0 at aa 46-68 and 88-107 216591028100 DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701 216591028101 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591028102 active site 216591028103 phosphorylation site [posttranslational modification] 216591028104 intermolecular recognition site; other site 216591028105 dimerization interface [polypeptide binding]; other site 216591028106 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591028107 DNA binding site [nucleotide binding] 216591028108 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.9e-19 216591028109 HMMPfam hit to PF00072, Response regulator receiver domain, score 8.4e-27 216591028110 Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066 216591028111 glutaminase; Provisional; Region: PRK00971 216591028112 HMMPfam hit to PF04960, Glutaminase, score 1.1e-163 216591028113 PS00012 Phosphopantetheine attachment site. 216591028114 Isochorismatase family; Region: Isochorismatase; pfam00857 216591028115 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431 216591028116 catalytic triad [active] 216591028117 conserved cis-peptide bond; other site 216591028118 HMMPfam hit to PF00857, Isochorismatase family, score 2e-07 216591028119 Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases). Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062 216591028120 B1 nucleotide binding pocket [chemical binding]; other site 216591028121 B2 nucleotide binding pocket [chemical binding]; other site 216591028122 CAS motifs; other site 216591028123 active site 216591028124 HMMPfam hit to PF00445, Ribonuclease T2 family, score 6.8e-08 216591028125 PS00531 Ribonuclease T2 family histidine active site 2. 216591028126 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028127 PS00530 Ribonuclease T2 family histidine active site 1. 216591028128 Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765 216591028129 HMMPfam hit to PF02566, OsmC-like protein, score 4.9e-17 216591028130 1 probable transmembrane helix predicted for BCAM2181 by TMHMM2.0 at aa 7-26 216591028131 6 probable transmembrane helices predicted for BCAM2182 by TMHMM2.0 at aa 21-40, 50-72, 79-96, 100-122, 129-151 and 156-178 216591028132 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591028133 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591028134 non-specific DNA binding site [nucleotide binding]; other site 216591028135 salt bridge; other site 216591028136 sequence-specific DNA binding site [nucleotide binding]; other site 216591028137 Predicted helix-turn-helix motif with score 1997.000, SD 5.99 at aa 24-45, sequence VKQSHAAELFRVAQSTISRWEA 216591028138 HD domain; Region: HD_3; pfam13023 216591028139 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591028140 S-adenosylmethionine binding site [chemical binding]; other site 216591028141 HMMPfam hit to PF08241, Methyltransferase domain, score 1.4e-29 216591028142 HMMPfam hit to PF08242, Methyltransferase domain, score 4.4e-18 216591028143 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 216591028144 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591028145 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591028146 1 probable transmembrane helix predicted for BCAM2186 by TMHMM2.0 at aa 12-31 216591028147 HMMPfam hit to PF00529, HlyD family secretion protein, score 0.0003 216591028148 macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535 216591028149 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 216591028150 Walker A/P-loop; other site 216591028151 ATP binding site [chemical binding]; other site 216591028152 Q-loop/lid; other site 216591028153 ABC transporter signature motif; other site 216591028154 Walker B; other site 216591028155 D-loop; other site 216591028156 H-loop/switch region; other site 216591028157 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 216591028158 FtsX-like permease family; Region: FtsX; pfam02687 216591028159 HMMPfam hit to PF00005, ABC transporter score 1.3e-61 216591028160 PS00017 ATP/GTP-binding site motif A (P-loop). 216591028161 PS00211 ABC transporters family signature. 216591028162 4 probable transmembrane helices predicted for BCAM2187 by TMHMM2.0 at aa 303-325, 560-582, 609-631 and 641-663 216591028163 HMMPfam hit to PF02687, Predicted permease, score 1.3e-52 216591028164 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591028165 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028166 HMMPfam hit to PF02321, Outer membrane efflux protein, score 4.6e-23 216591028167 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.4e-19 216591028168 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591028169 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591028170 14 probable transmembrane helices predicted for BCAM2189 by TMHMM2.0 at aa 37-59, 74-96, 103-125, 129-151, 164-186, 191-213, 222-244, 254-273, 294-316, 320-342, 349-371, 381-400, 430-452 and 505-527 216591028171 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.3e-52 216591028172 PS00216 Sugar transport proteins signature 1. 216591028173 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591028174 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591028175 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_6; cd08475 216591028176 putative effector binding pocket; other site 216591028177 putative dimerization interface [polypeptide binding]; other site 216591028178 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.9e-18 216591028179 Predicted helix-turn-helix motif with score 1385.000, SD 3.90 at aa 18-39, sequence GSFALAAERLDMTRSAVGKAIA 216591028180 PS00044 Bacterial regulatory proteins, lysR family signature. 216591028181 HMMPfam hit to PF03466, LysR substrate binding domain, score 7.5e-44 216591028182 3-hydroxyisobutyryl-CoA hydrolase; Provisional; Region: PRK05617 216591028183 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591028184 substrate binding site [chemical binding]; other site 216591028185 oxyanion hole (OAH) forming residues; other site 216591028186 trimer interface [polypeptide binding]; other site 216591028187 2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766 216591028188 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 5.3e-31 216591028189 enoyl-CoA hydratase; Provisional; Region: PRK09076 216591028190 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591028191 substrate binding site [chemical binding]; other site 216591028192 oxyanion hole (OAH) forming residues; other site 216591028193 trimer interface [polypeptide binding]; other site 216591028194 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 9.8e-47 216591028195 PS00166 Enoyl-CoA hydratase/isomerase signature. 216591028196 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 216591028197 3-hydroxyisobutyrate dehydrogenase; Region: HIBADH; TIGR01692 216591028198 HMMPfam hit to PF03807, NADP oxidoreductase coenzyme F420-depen, score 0.0017 216591028199 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 4.9e-79 216591028200 PS00895 3-hydroxyisobutyrate dehydrogenase signature. 216591028201 Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085 216591028202 methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722 216591028203 tetrameric interface [polypeptide binding]; other site 216591028204 NAD binding site [chemical binding]; other site 216591028205 catalytic residues [active] 216591028206 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.4e-179 216591028207 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591028208 PS00070 Aldehyde dehydrogenases cysteine active site. 216591028209 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365 216591028210 Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS); Region: MACS_like_1; cd05974 216591028211 active site 216591028212 acyl-activating enzyme (AAE) consensus motif; other site 216591028213 putative CoA binding site [chemical binding]; other site 216591028214 AMP binding site [chemical binding]; other site 216591028215 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.7e-112 216591028216 PS00455 Putative AMP-binding domain signature. 216591028217 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591028218 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591028219 active site 216591028220 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 3.2e-66 216591028221 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 3.3e-37 216591028222 PS00073 Acyl-CoA dehydrogenases signature 2. 216591028223 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 2.7e-24 216591028224 HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal doma, score 1.5e-35 216591028225 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 216591028226 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591028227 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591028228 1 probable transmembrane helix predicted for BCAM2197 by TMHMM2.0 at aa 137-159 216591028229 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.8e-06 216591028230 Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030 216591028231 Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_1; cd07020 216591028232 active site residues [active] 216591028233 dimer interface [polypeptide binding]; other site 216591028234 NfeD-like C-terminal, partner-binding; Region: NfeD; pfam01957 216591028235 5 probable transmembrane helices predicted for BCAM2198 by TMHMM2.0 at aa 299-321, 328-347, 352-369, 376-395 and 405-427 216591028236 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028237 HMMPfam hit to PF01957, Nodulation efficiency protein D (NfeD), score 1.9e-46 216591028238 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028239 Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330 216591028240 Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403 216591028241 1 probable transmembrane helix predicted for BCAM2199 by TMHMM2.0 at aa 5-27 216591028242 HMMPfam hit to PF01145, SPFH domain / Band, score 5.9e-75 216591028243 haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710 216591028244 A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066 216591028245 active site 216591028246 short chain dehydrogenase; Validated; Region: PRK05855 216591028247 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591028248 classical (c) SDRs; Region: SDR_c; cd05233 216591028249 NAD(P) binding site [chemical binding]; other site 216591028250 active site 216591028251 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 3.6e-07 216591028252 HMMPfam hit to PF00106, short chain dehydrogenase, score 1e-21 216591028253 PS00061 Short-chain dehydrogenases/reductases family signature. 216591028254 Predicted metal-dependent hydrolase [General function prediction only]; Region: COG3687 216591028255 Predicted metal-dependent hydrolase; Region: Metal_hydrol; pfam10118 216591028256 1 probable transmembrane helix predicted for BCAM2203 by TMHMM2.0 at aa 200-222 216591028257 Protein of unknown function (DUF2917); Region: DUF2917; pfam11142 216591028258 Protein of unknown function (DUF2917); Region: DUF2917; pfam11142 216591028259 Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism]; Region: COG2252 216591028260 HMMPfam hit to PF00860, Permease family, score 2e-44 216591028261 10 probable transmembrane helices predicted for BCAM2208 by TMHMM2.0 at aa 20-42, 54-76, 96-118, 135-157, 172-189, 196-218, 233-255, 325-347, 380-402 and 415-432 216591028262 PS00310 Lysosome-associated membrane glycoproteins duplicated domain signature. 216591028263 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028264 HMMPfam hit to PF00916, Sulfate transporter family, score 0.0044 216591028265 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028266 Protein of unknown function (DUF1488); Region: DUF1488; pfam07369 216591028267 PS00153 ATP synthase gamma subunit signature. 216591028268 Protein of unknown function (DUF2964); Region: DUF2964; pfam11177 216591028269 2 probable transmembrane helices predicted for BCAM2210 by TMHMM2.0 at aa 34-56 and 61-83 216591028270 Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284 216591028271 GAF domain; Region: GAF; pfam01590 216591028272 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591028273 Walker A motif; other site 216591028274 ATP binding site [chemical binding]; other site 216591028275 Walker B motif; other site 216591028276 arginine finger; other site 216591028277 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591028278 HMMPfam hit to PF01590, GAF domain, score 6e-19 216591028279 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3.7e-120 216591028280 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591028281 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591028282 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 2.9e-09 216591028283 Predicted helix-turn-helix motif with score 1827.000, SD 5.41 at aa 611-632, sequence GNVSAAARELGLARNTVYRYLR 216591028284 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591028285 catalytic loop [active] 216591028286 iron binding site [ion binding]; other site 216591028287 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 3.9e-19 216591028288 Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_5; cd08898 216591028289 putative hydrophobic ligand binding site [chemical binding]; other site 216591028290 Protein of unknown function (DUF2946); Region: DUF2946; pfam11162 216591028291 1 probable transmembrane helix predicted for BCAM2214 by TMHMM2.0 at aa 9-31 216591028292 CopC domain; Region: CopC; pfam04234 216591028293 HMMPfam hit to PF04234, Copper resistance protein CopC, score 5.2e-21 216591028294 1 probable transmembrane helix predicted for BCAM2215 by TMHMM2.0 at aa 5-27 216591028295 Protein of unknown function (DUF461); Region: DUF461; pfam04314 216591028296 Signal peptide predicted for BCAM2216 by SignalP 3.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.989 between residues 22 and 23 216591028297 HMMPfam hit to PF04314, Protein of unknown function (DUF461), score 2.5e-30 216591028298 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591028299 5 probable transmembrane helices predicted for BCAM2217 by TMHMM2.0 at aa 22-44, 57-79, 83-105, 135-157 and 167-189 216591028300 HMMPfam hit to PF01810, LysE type translocator, score 2.2e-32 216591028301 PS00043 Bacterial regulatory proteins, gntR family signature. 216591028302 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028303 Leucine rich repeat; Region: LRR_8; pfam13855 216591028304 Protein Kinases, catalytic domain; Region: PKc_like; cl09925 216591028305 active site 216591028306 ATP binding site [chemical binding]; other site 216591028307 substrate binding site [chemical binding]; other site 216591028308 HMMPfam hit to PF00069, Protein kinase domain, score 2.1e-07 216591028309 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028310 PS00107 Protein kinases ATP-binding region signature. 216591028311 HMMPfam hit to PF00560, Leucine Rich Repeat, score 4.8 216591028312 HMMPfam hit to PF00560, Leucine Rich Repeat, score 1.6 216591028313 HMMPfam hit to PF00560, Leucine Rich Repeat, score 3.7 216591028314 HMMPfam hit to PF00560, Leucine Rich Repeat, score 5.1 216591028315 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028316 HMMPfam hit to PF00560, Leucine Rich Repeat, score 0.096 216591028317 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 216591028318 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591028319 The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451 216591028320 putative dimerization interface [polypeptide binding]; other site 216591028321 putative substrate binding pocket [chemical binding]; other site 216591028322 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.8e-38 216591028323 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.3e-19 216591028324 Predicted helix-turn-helix motif with score 1578.000, SD 4.56 at aa 16-37, sequence SNFTKAAETLGIGQPPLSQQIK 216591028325 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591028326 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591028327 putative substrate translocation pore; other site 216591028328 12 probable transmembrane helices predicted for BCAM2220 by TMHMM2.0 at aa 35-57, 72-93, 100-122, 126-148, 155-177, 187-209, 239-261, 271-293, 300-322, 327-349, 362-384 and 388-407 216591028329 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.1e-38 216591028330 PS00216 Sugar transport proteins signature 1. 216591028331 siderophore transporter, RhtX/FptX family; Region: sider_RhtX_FptX; TIGR02718 216591028332 muropeptide transporter; Validated; Region: ampG; cl17669 216591028333 10 probable transmembrane helices predicted for BCAM2221 by TMHMM2.0 at aa 13-35, 50-72, 93-115, 150-172, 179-198, 227-249, 262-281, 285-307, 319-341 and 381-400 216591028334 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.5e-16 216591028335 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028336 PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703 216591028337 10 probable transmembrane helices predicted for BCAM2222 by TMHMM2.0 at aa 12-34, 130-152, 165-182, 186-208, 311-333, 338-360, 373-395, 410-428, 441-460 and 464-483 216591028338 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028339 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028340 HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.16 216591028341 3 probable transmembrane helices predicted for BCAM2223 by TMHMM2.0 at aa 5-27, 39-61 and 66-85 216591028342 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism]; Region: FhuE; COG4773 216591028343 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591028344 N-terminal plug; other site 216591028345 ligand-binding site [chemical binding]; other site 216591028346 HMMPfam hit to PF00593, TonB dependent receptor, score 7.3e-26 216591028347 PS01156 TonB-dependent receptor proteins signature 2. 216591028348 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 8e-14 216591028349 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 216591028350 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591028351 Walker A/P-loop; other site 216591028352 ATP binding site [chemical binding]; other site 216591028353 Q-loop/lid; other site 216591028354 ABC transporter signature motif; other site 216591028355 Walker B; other site 216591028356 D-loop; other site 216591028357 H-loop/switch region; other site 216591028358 HMMPfam hit to PF00005, ABC transporter score 2.8e-56 216591028359 PS00211 ABC transporters family signature. 216591028360 PS00017 ATP/GTP-binding site motif A (P-loop). 216591028361 5 probable transmembrane helices predicted for BCAM2225 by TMHMM2.0 at aa 23-45, 55-77, 128-150, 155-172 and 243-265 216591028362 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 216591028363 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591028364 Walker A/P-loop; other site 216591028365 ATP binding site [chemical binding]; other site 216591028366 Q-loop/lid; other site 216591028367 ABC transporter signature motif; other site 216591028368 Walker B; other site 216591028369 D-loop; other site 216591028370 H-loop/switch region; other site 216591028371 HMMPfam hit to PF00005, ABC transporter score 2.6e-57 216591028372 PS00211 ABC transporters family signature. 216591028373 PS00017 ATP/GTP-binding site motif A (P-loop). 216591028374 5 probable transmembrane helices predicted for BCAM2226 by TMHMM2.0 at aa 15-37, 50-72, 146-168, 243-262 and 267-289 216591028375 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028376 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PchG; COG4693 216591028377 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 216591028378 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Rossm, score 3.3e-25 216591028379 CDS contains a frameshift after codon 596. Similar to Pseudomonas aeruginosa pyochelin synthetase Pchf UniProt:Q9RFM7 (EMBL:AF184622 (1809 aa) fasta scores: E()=0, 61.778% id in 1834 aa 216591028380 HMMPfam hit to PF00975, Thioesterase domain, score 2.9e-05 216591028381 HMMPfam hit to PF08242, Methyltransferase domain, score 2.1e-11 216591028382 HMMPfam hit to PF00501, AMP-binding enzyme, score 9.3e-131 216591028383 HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 1.2e-24 216591028384 HMMPfam hit to PF00668, Condensation domain, score 9.5e-19 216591028385 Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433 216591028386 Condensation domain; Region: Condensation; pfam00668 216591028387 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 216591028388 Nonribosomal peptide synthase; Region: NRPS; pfam08415 216591028389 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114 216591028390 acyl-activating enzyme (AAE) consensus motif; other site 216591028391 AMP binding site [chemical binding]; other site 216591028392 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591028393 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 216591028394 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.9e-14 216591028395 PS00012 Phosphopantetheine attachment site. 216591028396 HMMPfam hit to PF08241, Methyltransferase domain, score 0.00095 216591028397 HMMPfam hit to PF08242, Methyltransferase domain, score 0.00041 216591028398 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.5e-132 216591028399 PS00455 Putative AMP-binding domain signature. 216591028400 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028401 HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 3e-17 216591028402 HMMPfam hit to PF00668, Condensation domain, score 4e-28 216591028403 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.2e-06 216591028404 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591028405 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591028406 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.8e-08 216591028407 PS00041 Bacterial regulatory proteins, araC family signature. 216591028408 2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920 216591028409 Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021 216591028410 acyl-activating enzyme (AAE) consensus motif; other site 216591028411 active site 216591028412 AMP binding site [chemical binding]; other site 216591028413 substrate binding site [chemical binding]; other site 216591028414 HMMPfam hit to PF00501, AMP-binding enzyme, score 4.3e-106 216591028415 PS00455 Putative AMP-binding domain signature. 216591028416 Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208 216591028417 Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883 216591028418 nucleophilic elbow; other site 216591028419 catalytic triad; other site 216591028420 HMMPfam hit to PF00975, Thioesterase domain, score 7e-56 216591028421 isochorismate-pyruvate lyase; Reviewed; Region: PRK07075 216591028422 HMMPfam hit to PF01817, Chorismate mutase type II, score 1.1e-22 216591028423 salicylate biosynthesis isochorismate synthase; Validated; Region: PRK07054 216591028424 chorismate binding enzyme; Region: Chorismate_bind; cl10555 216591028425 HMMPfam hit to PF00425, chorismate binding enzyme, score 1.2e-89 216591028426 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591028427 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591028428 The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439 216591028429 putative dimerization interface [polypeptide binding]; other site 216591028430 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.1e-30 216591028431 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.1e-18 216591028432 PS00044 Bacterial regulatory proteins, lysR family signature. 216591028433 Predicted helix-turn-helix motif with score 1195.000, SD 3.26 at aa 29-50, sequence RALSRAAARVGRTQSALSQQMK 216591028434 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591028435 4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Region: GabT; COG0160 216591028436 inhibitor-cofactor binding pocket; inhibition site 216591028437 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591028438 catalytic residue [active] 216591028439 HMMPfam hit to PF00202, Aminotransferase class-III, score 9.7e-167 216591028440 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591028441 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374 216591028442 Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221 216591028443 NADP binding site [chemical binding]; other site 216591028444 active site 216591028445 steroid binding site; other site 216591028446 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00021 216591028447 HMMPfam hit to PF00106, short chain dehydrogenase, score 8.3e-19 216591028448 Cupin; Region: Cupin_6; pfam12852 216591028449 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591028450 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591028451 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591028452 PS00041 Bacterial regulatory proteins, araC family signature. 216591028453 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 6.6e-07 216591028454 Predicted helix-turn-helix motif with score 1046.000, SD 2.75 at aa 213-234, sequence WTIVELAKEAALSRSTFFERFS 216591028455 PS00041 Bacterial regulatory proteins, araC family signature. 216591028456 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.2e-07 216591028457 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 216591028458 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591028459 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591028460 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591028461 HMMPfam hit to PF02311, AraC-like ligand binding domain, score 1.6e-21 216591028462 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 4.4e-09 216591028463 Protein of unknown function (DUF2000); Region: DUF2000; pfam09391 216591028464 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591028465 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_5; cd07238 216591028466 dimer interface [polypeptide binding]; other site 216591028467 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 2.4e-10 216591028468 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 216591028469 EamA-like transporter family; Region: EamA; pfam00892 216591028470 EamA-like transporter family; Region: EamA; pfam00892 216591028471 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 3.7e-11 216591028472 9 probable transmembrane helices predicted for BCAM2243 by TMHMM2.0 at aa 28-50, 63-85, 90-112, 119-141, 145-162, 183-205, 215-237, 249-266 and 271-288 216591028473 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028474 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 7.3e-14 216591028475 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640 216591028476 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591028477 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591028478 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591028479 dimerization interface [polypeptide binding]; other site 216591028480 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.3e-13 216591028481 Predicted helix-turn-helix motif with score 1125.000, SD 3.02 at aa 20-41, sequence GRFKDAAVHVNRSPSSVTAQIQ 216591028482 PS00044 Bacterial regulatory proteins, lysR family signature. 216591028483 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.8e-18 216591028484 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 216591028485 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 216591028486 Walker A/P-loop; other site 216591028487 ATP binding site [chemical binding]; other site 216591028488 Q-loop/lid; other site 216591028489 ABC transporter signature motif; other site 216591028490 Walker B; other site 216591028491 D-loop; other site 216591028492 H-loop/switch region; other site 216591028493 HMMPfam hit to PF00005, ABC transporter score 3e-50 216591028494 PS00211 ABC transporters family signature. 216591028495 PS00017 ATP/GTP-binding site motif A (P-loop). 216591028496 leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300 216591028497 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 216591028498 Walker A/P-loop; other site 216591028499 ATP binding site [chemical binding]; other site 216591028500 Q-loop/lid; other site 216591028501 ABC transporter signature motif; other site 216591028502 Walker B; other site 216591028503 D-loop; other site 216591028504 H-loop/switch region; other site 216591028505 HMMPfam hit to PF00005, ABC transporter score 7.8e-59 216591028506 PS00063 Aldo/keto reductase family putative active site signature. 216591028507 PS00017 ATP/GTP-binding site motif A (P-loop). 216591028508 leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301 216591028509 Domain of unknown function (DUF3382); Region: DUF3382; pfam11862 216591028510 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 216591028511 TM-ABC transporter signature motif; other site 216591028512 9 probable transmembrane helices predicted for BCAM2249 by TMHMM2.0 at aa 20-42, 57-76, 97-114, 124-155, 168-190, 267-289, 317-339, 354-376 and 388-406 216591028513 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 5e-56 216591028514 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591028515 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 216591028516 TM-ABC transporter signature motif; other site 216591028517 8 probable transmembrane helices predicted for BCAM2250 by TMHMM2.0 at aa 28-50, 57-76, 80-102, 115-137, 164-186, 217-239, 254-276 and 293-310 216591028518 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.6e-48 216591028519 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591028520 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 216591028521 dimerization interface [polypeptide binding]; other site 216591028522 ligand binding site [chemical binding]; other site 216591028523 HMMPfam hit to PF01094, Receptor family ligand binding region, score 1.7e-68 216591028524 Similar to an internal region of Burkholderia xenovorans (strain lb400) YD repeat protein UniProt:Q13ML3 (EMBL:CP000271 (1531 aa) fasta scores: E()=3.7e-41, 38.407% id in 427 aa 216591028525 HMMPfam hit to PF05593, RHS Repeat, score 0.013 216591028526 HMMPfam hit to PF05593, RHS Repeat, score 0.49 216591028527 HMMPfam hit to PF05593, RHS Repeat, score 6.7 216591028528 HMMPfam hit to PF05593, RHS Repeat, score 0.0038 216591028529 HMMPfam hit to PF05593, RHS Repeat, score 3.8e-06 216591028530 PAAR motif; Region: PAAR_motif; pfam05488 216591028531 RHS Repeat; Region: RHS_repeat; cl11982 216591028532 Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871 216591028533 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 216591028534 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 216591028535 RHS Repeat; Region: RHS_repeat; pfam05593 216591028536 RHS Repeat; Region: RHS_repeat; cl11982 216591028537 RHS Repeat; Region: RHS_repeat; pfam05593 216591028538 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 216591028539 RHS protein; Region: RHS; pfam03527 216591028540 RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696 216591028541 RES domain; Region: RES; smart00953 216591028542 HMMPfam hit to PF05593, RHS Repeat, score 3.6e-05 216591028543 HMMPfam hit to PF05593, RHS Repeat, score 0.11 216591028544 HMMPfam hit to PF05593, RHS Repeat, score 0.045 216591028545 HMMPfam hit to PF05593, RHS Repeat, score 0.88 216591028546 HMMPfam hit to PF05593, RHS Repeat, score 2e-06 216591028547 HMMPfam hit to PF05593, RHS Repeat, score 7.1e-07 216591028548 HMMPfam hit to PF05593, RHS Repeat, score 0.063 216591028549 HMMPfam hit to PF05593, RHS Repeat, score 0.63 216591028550 HMMPfam hit to PF05593, RHS Repeat, score 2.4 216591028551 HMMPfam hit to PF05593, RHS Repeat, score 1.4e-06 216591028552 HMMPfam hit to PF05593, RHS Repeat, score 2.3e-06 216591028553 HMMPfam hit to PF05593, RHS Repeat, score 1.8 216591028554 HMMPfam hit to PF05593, RHS Repeat, score 0.049 216591028555 HMMPfam hit to PF05593, RHS Repeat, score 0.8 216591028556 HMMPfam hit to PF05488, PAAR motif, score 1.2e-05 216591028557 HMMPfam hit to PF05488, PAAR motif, score 1.4e-07 216591028558 4 probable transmembrane helices predicted for BCAM2253 by TMHMM2.0 at aa 50-72, 79-101, 146-168 and 173-195 216591028559 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028560 Domain of unknown function (DUF1795); Region: DUF1795; cl02256 216591028561 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 216591028562 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 216591028563 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 216591028564 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 2.7e-39 216591028565 putative outer membrane lipoprotein; Provisional; Region: PRK09967 216591028566 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591028567 ligand binding site [chemical binding]; other site 216591028568 HMMPfam hit to PF00691, OmpA family, score 1.1e-25 216591028569 PS00017 ATP/GTP-binding site motif A (P-loop). 216591028570 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028571 putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966 216591028572 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591028573 metal binding site [ion binding]; metal-binding site 216591028574 active site 216591028575 I-site; other site 216591028576 HMMPfam hit to PF00990, GGDEF domain, score 4.6e-55 216591028577 HMMPfam hit to PF00672, HAMP domain, score 4.4e-09 216591028578 2 probable transmembrane helices predicted for BCAM2256 by TMHMM2.0 at aa 27-49 and 156-178 216591028579 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028580 Domain of unknown function (DUF4154); Region: DUF4154; pfam13689 216591028581 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591028582 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591028583 TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440 216591028584 putative dimerization interface [polypeptide binding]; other site 216591028585 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.5e-20 216591028586 Predicted helix-turn-helix motif with score 1625.000, SD 4.72 at aa 28-49, sequence GTFHRAAEKLNLTQPGLSRRIQ 216591028587 PS00044 Bacterial regulatory proteins, lysR family signature. 216591028588 HMMPfam hit to PF03466, LysR substrate binding domain, score 5.2e-41 216591028589 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028590 N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653 216591028591 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 216591028592 active site 216591028593 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 216591028594 PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 216591028595 HMMPfam hit to PF01979, Amidohydrolase family, score 0.024 216591028596 HMMPfam hit to PF07969, Amidohydrolase family, score 2.8e-09 216591028597 PS00190 Cytochrome c family heme-binding site signature. 216591028598 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591028599 HMMPfam hit to PF07908, D-aminoacylase, C-terminal region, score 9.2e-20 216591028600 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591028601 D-galactonate transporter; Region: 2A0114; TIGR00893 216591028602 putative substrate translocation pore; other site 216591028603 12 probable transmembrane helices predicted for BCAM2260 by TMHMM2.0 at aa 38-60, 75-97, 104-123, 133-155, 164-186, 196-218, 261-283, 298-315, 328-347, 352-374, 387-409 and 419-438 216591028604 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.6e-51 216591028605 amidase; Provisional; Region: PRK09201 216591028606 Amidase; Region: Amidase; cl11426 216591028607 HMMPfam hit to PF01425, Amidase, score 2.2e-90 216591028608 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 216591028609 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 216591028610 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591028611 HMMPfam hit to PF02738, Aldehyde oxidase and xanthine dehydroge, score 3.2e-06 216591028612 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080 216591028613 Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868 216591028614 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 216591028615 HMMPfam hit to PF01799, [2Fe-2S] binding domain, score 1.2e-30 216591028616 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 5.9e-10 216591028617 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591028618 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591028619 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591028620 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591028621 dimerization interface [polypeptide binding]; other site 216591028622 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.3e-16 216591028623 Predicted helix-turn-helix motif with score 1696.000, SD 4.96 at aa 21-42, sequence GSFSSAARQLALTHSAISQQIR 216591028624 PS00044 Bacterial regulatory proteins, lysR family signature. 216591028625 HMMPfam hit to PF03466, LysR substrate binding domain, score 8.3e-22 216591028626 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028627 DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986 216591028628 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591028629 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591028630 dimerization interface [polypeptide binding]; other site 216591028631 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.8e-45 216591028632 PS00017 ATP/GTP-binding site motif A (P-loop). 216591028633 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.9e-20 216591028634 PS00044 Bacterial regulatory proteins, lysR family signature. 216591028635 Predicted helix-turn-helix motif with score 1536.000, SD 4.42 at aa 16-37, sequence LHFGRAAARLHISQPPLSQQIR 216591028636 Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG2159 216591028637 HMMPfam hit to PF04909, Amidohydrolase, score 1.9e-37 216591028638 Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG2159 216591028639 active site 216591028640 HMMPfam hit to PF04909, Amidohydrolase, score 2.6e-50 216591028641 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; pfam01977 216591028642 HMMPfam hit to PF01977, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, score 1.1e-76 216591028643 3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163 216591028644 Flavoprotein; Region: Flavoprotein; pfam02441 216591028645 HMMPfam hit to PF02441, Flavoprotein, score 1.1e-42 216591028646 Putative GTPases (G3E family) [General function prediction only]; Region: COG0523 216591028647 The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112 216591028648 P-loop, Walker A motif; other site 216591028649 Base recognition motif; other site 216591028650 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683 216591028651 HMMPfam hit to PF02492, CobW/HypB/UreG, nucleotide-binding domain, score 2.4e-78 216591028652 PS00017 ATP/GTP-binding site motif A (P-loop). 216591028653 HMMPfam hit to PF07683, Cobalamin synthesis protein cobW C-terminal, score 2.5e-29 216591028654 xanthine permease; Region: pbuX; TIGR03173 216591028655 HMMPfam hit to PF00860, Permease family, score 4.7e-110 216591028656 13 probable transmembrane helices predicted for BCAM2271 by TMHMM2.0 at aa 20-40, 50-72, 79-98, 103-125, 132-154, 164-186, 193-215, 230-252, 281-303, 318-340, 347-369, 379-401 and 414-436 216591028657 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028658 amidohydrolase; Provisional; Region: PRK12393 216591028659 TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298 216591028660 active site 216591028661 putative substrate binding pocket [chemical binding]; other site 216591028662 HMMPfam hit to PF01979, Amidohydrolase family, score 3.2e-43 216591028663 HMMPfam hit to PF07969, Amidohydrolase family, score 0.00086 216591028664 Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518 216591028665 HMMPfam hit to PF01177, Asp/Glu/Hydantoin racemase, score 7.5e-06 216591028666 Domain of unknown function (DUF4411); Region: DUF4411; pfam14367 216591028667 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591028668 non-specific DNA binding site [nucleotide binding]; other site 216591028669 salt bridge; other site 216591028670 sequence-specific DNA binding site [nucleotide binding]; other site 216591028671 Predicted Zn peptidase [Amino acid transport and metabolism]; Region: COG2856 216591028672 HMMPfam hit to PF06114, Domain of unknown function (DUF955), score 3.5e-27 216591028673 Predicted helix-turn-helix motif with score 1045.000, SD 2.75 at aa 286-307, sequence EMFAELASYFGVSREAVLRRLL 216591028674 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591028675 HMMPfam hit to PF01381, Helix-turn-helix, score 1.1e-05 216591028676 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591028677 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 216591028678 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.3e-76 216591028679 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591028680 Isopentenyl diphosphate isomerase (BS_ypgA, MTH48 and related proteins) [Coenzyme transport and metabolism]; Region: idi; COG1304 216591028681 TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186 216591028682 phosphate binding site [ion binding]; other site 216591028683 HMMPfam hit to PF01070, FMN-dependent dehydrogenase, score 7.2e-145 216591028684 PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 216591028685 Transcriptional regulators [Transcription]; Region: FadR; COG2186 216591028686 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591028687 DNA-binding site [nucleotide binding]; DNA binding site 216591028688 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 216591028689 HMMPfam hit to PF07729, FCD domain, score 8.7e-30 216591028690 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 1.3e-28 216591028691 PS00043 Bacterial regulatory proteins, gntR family signature. 216591028692 Predicted helix-turn-helix motif with score 1186.000, SD 3.23 at aa 35-56, sequence PPERELAERFGVSRTSVREALI 216591028693 Amidohydrolase; Region: Amidohydro_2; pfam04909 216591028694 Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618 216591028695 HMMPfam hit to PF04909, Amidohydrolase, score 1.8e-22 216591028696 Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_2; cd06310 216591028697 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 216591028698 putative ligand binding site [chemical binding]; other site 216591028699 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 0.00028 216591028700 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591028701 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591028702 TM-ABC transporter signature motif; other site 216591028703 9 probable transmembrane helices predicted for BCAM2281 by TMHMM2.0 at aa 36-57, 62-84, 88-107, 114-136, 141-163, 183-205, 242-261, 281-303 and 318-340 216591028704 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 9e-64 216591028705 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028706 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028707 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 216591028708 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 216591028709 Walker A/P-loop; other site 216591028710 ATP binding site [chemical binding]; other site 216591028711 Q-loop/lid; other site 216591028712 ABC transporter signature motif; other site 216591028713 Walker B; other site 216591028714 D-loop; other site 216591028715 H-loop/switch region; other site 216591028716 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 216591028717 HMMPfam hit to PF00005, ABC transporter score 7.9e-23 216591028718 PS00211 ABC transporters family signature. 216591028719 HMMPfam hit to PF00005, ABC transporter score 2.9e-54 216591028720 PS00017 ATP/GTP-binding site motif A (P-loop). 216591028721 short chain dehydrogenase; Provisional; Region: PRK08628 216591028722 classical (c) SDRs; Region: SDR_c; cd05233 216591028723 NAD(P) binding site [chemical binding]; other site 216591028724 active site 216591028725 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.2e-17 216591028726 Human rTS beta is encoded by the rTS gene which, through alternative RNA splicing, also encodes rTS alpha whose mRNA is complementary to thymidylate synthase mRNA. rTS beta expression is associated with the production of small molecules that appear to...; Region: rTSbeta_L-fuconate_dehydratase; cd03324 216591028727 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948 216591028728 putative active site pocket [active] 216591028729 metal binding site [ion binding]; metal-binding site 216591028730 HMMPfam hit to PF01188, Mandelate racemase / muconate lactonizing en, score 1.5e-09 216591028731 PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 216591028732 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 216591028733 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 216591028734 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 8.7e-76 216591028735 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 216591028736 human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368 216591028737 NAD binding site [chemical binding]; other site 216591028738 homotetramer interface [polypeptide binding]; other site 216591028739 homodimer interface [polypeptide binding]; other site 216591028740 active site 216591028741 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00019 216591028742 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.1e-15 216591028743 PS00061 Short-chain dehydrogenases/reductases family signature. 216591028744 Domain of unknown function (DUF3331); Region: DUF3331; pfam11811 216591028745 short chain dehydrogenase; Provisional; Region: PRK06197 216591028746 retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327 216591028747 putative NAD(P) binding site [chemical binding]; other site 216591028748 active site 216591028749 HMMPfam hit to PF00106, short chain dehydrogenase, score 6.5e-07 216591028750 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591028751 gamma-butyrobetaine hydroxylase; Region: carnitine_bodg; TIGR02409 216591028752 Protein of unknown function (DUF971); Region: DUF971; cl01414 216591028753 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250 216591028754 substrate binding pocket [chemical binding]; other site 216591028755 active site 216591028756 iron coordination sites [ion binding]; other site 216591028757 HMMPfam hit to PF02668, Taurine catabolism dioxygenase TauD, TfdA fa, score 2.2e-23 216591028758 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 216591028759 HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 2.1e-61 216591028760 PS01174 Lipolytic enzymes G-D-X-G family, putative serine active site. 216591028761 PS01173 Lipolytic enzymes G-D-X-G family, putative histidine active site. 216591028762 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 216591028763 active site 216591028764 3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK07066 216591028765 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 216591028766 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 216591028767 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 1.7e-15 216591028768 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD binding, score 8.9e-60 216591028769 Prokaryotic protein of unknown function (DUF849); Region: DUF849; pfam05853 216591028770 HMMPfam hit to PF05853, Prokaryotic protein of unknown function (DUF, score 1.1e-202 216591028771 choline ABC transporter, periplasmic binding protein; Region: ABC_choline_bnd; TIGR03414 216591028772 ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113 216591028773 HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 6.1e-64 216591028774 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591028775 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591028776 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 216591028777 dimerization interface [polypeptide binding]; other site 216591028778 substrate binding pocket [chemical binding]; other site 216591028779 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.8e-31 216591028780 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.8e-21 216591028781 PS00044 Bacterial regulatory proteins, lysR family signature. 216591028782 Predicted helix-turn-helix motif with score 1249.000, SD 3.44 at aa 17-38, sequence GGFTPAAGALHVAQSALSRQIG 216591028783 Protein of unknown function, DUF606; Region: DUF606; pfam04657 216591028784 HMMPfam hit to PF04657, Protein of unknown function, DUF606, score 1.8e-26 216591028785 5 probable transmembrane helices predicted for BCAM2297 by TMHMM2.0 at aa 5-27, 34-56, 71-93, 100-122 and 127-145 216591028786 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 216591028787 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591028788 NAD(P) binding site [chemical binding]; other site 216591028789 catalytic residues [active] 216591028790 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 4.3e-250 216591028791 PS00070 Aldehyde dehydrogenases cysteine active site. 216591028792 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591028793 PS00017 ATP/GTP-binding site motif A (P-loop). 216591028794 Cytochrome c; Region: Cytochrom_C; pfam00034 216591028795 HMMPfam hit to PF00034, Cytochrome c, score 0.022 216591028796 PS00190 Cytochrome c family heme-binding site signature. 216591028797 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028798 Cytochrome c; Region: Cytochrom_C; pfam00034 216591028799 HMMPfam hit to PF00034, Cytochrome c, score 2.7e-08 216591028800 PS00190 Cytochrome c family heme-binding site signature. 216591028801 Methylamine dehydrogenase, L chain; Region: Me-amine-dh_L; cl03812 216591028802 HMMPfam hit to PF02975, Methylamine dehydrogenase, L chain, score 5e-36 216591028803 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028804 Methylamine utilization (mau) D family; mauD protein is the translation product of the mauD gene found in methylotrophic bacteria, which are able to use methylamine as a sole carbon source and a nitrogen source. mauD is an essential accessory protein for...; Region: mauD; cd02967 216591028805 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591028806 catalytic residues [active] 216591028807 HMMPfam hit to PF08534, Redoxin, score 1.5e-05 216591028808 1 probable transmembrane helix predicted for BCAM2302A by TMHMM2.0 at aa 5-27 216591028809 Methylamine utilisation protein MauE; Region: MauE; pfam07291 216591028810 5 probable transmembrane helices predicted for BCAM2303 by TMHMM2.0 at aa 6-25, 46-68, 73-95, 119-138 and 153-175 216591028811 methylamine dehydrogenase (amicyanin) heavy chain; Region: TTQ_MADH_Hv; TIGR02658 216591028812 HMMPfam hit to PF06433, Methylamine dehydrogenase heavy chain (, score 1.2e-26 216591028813 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591028814 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591028815 PS00041 Bacterial regulatory proteins, araC family signature. 216591028816 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 5.6e-05 216591028817 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591028818 AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136 216591028819 conserved cys residue [active] 216591028820 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591028821 HMMPfam hit to PF01965, DJ-1/PfpI family, score 2.2e-05 216591028822 Predicted helix-turn-helix motif with score 1133.000, SD 3.05 at aa 228-249, sequence LGSDALAREVSITRRQLERLFS 216591028823 PS00041 Bacterial regulatory proteins, araC family signature. 216591028824 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.8e-13 216591028825 Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504 216591028826 Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413 216591028827 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 216591028828 Zn binding site [ion binding]; other site 216591028829 1 probable transmembrane helix predicted for BCAM2307 by TMHMM2.0 at aa 7-26 216591028830 HMMPfam hit to PF07504, Fungalysin/Thermolysin Propeptide Motif, score 1.4e-07 216591028831 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591028832 M28 Zn-Peptidase Aeromonas (Vibrio) proteolytica aminopeptidase; Region: M28_AAP; cd03879 216591028833 Peptidase family M28; Region: Peptidase_M28; pfam04389 216591028834 active site 216591028835 metal binding site [ion binding]; metal-binding site 216591028836 1 probable transmembrane helix predicted for BCAM2308 by TMHMM2.0 at aa 9-31 216591028837 HMMPfam hit to PF04389, Peptidase family M28, score 7.8e-40 216591028838 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 0.002 216591028839 Putative heavy-metal-binding; Region: YbjQ_1; cl00426 216591028840 HMMPfam hit to PF01906, Domain of unknown function DUF74, score 5.3e-32 216591028841 H+ Antiporter protein; Region: 2A0121; TIGR00900 216591028842 HMMPfam hit to PF05977, Bacterial protein of unknown function (DUF89, score 1.8e-05 216591028843 8 probable transmembrane helices predicted for BCAM2310 by TMHMM2.0 at aa 32-51, 56-78, 99-121, 172-194, 228-250, 265-284, 297-319 and 377-399 216591028844 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.4e-21 216591028845 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591028846 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591028847 trimer interface [polypeptide binding]; other site 216591028848 eyelet of channel; other site 216591028849 HMMPfam hit to PF00267, Gram-negative porin, score 2.7e-05 216591028850 choline ABC transporter, periplasmic binding protein; Region: ABC_choline_bnd; TIGR03414 216591028851 ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113 216591028852 HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 1.2e-72 216591028853 choline-sulfatase; Region: chol_sulfatase; TIGR03417 216591028854 Sulfatase; Region: Sulfatase; cl17466 216591028855 Choline sulfatase enzyme C terminal; Region: Choline_sulf_C; pfam12411 216591028856 HMMPfam hit to PF00884, Sulfatase, score 3.4e-39 216591028857 PS00387 Inorganic pyrophosphatase signature. 216591028858 PS00523 Sulfatases signature 1. 216591028859 putative choline sulfate-utilization transcription factor; Region: chol_sulf_TF; TIGR03418 216591028860 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591028861 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591028862 dimerization interface [polypeptide binding]; other site 216591028863 substrate binding pocket [chemical binding]; other site 216591028864 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.5e-18 216591028865 Predicted helix-turn-helix motif with score 1425.000, SD 4.04 at aa 30-51, sequence ASFTAAARELGSTQPAVSQQVY 216591028866 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-33 216591028867 formyltetrahydrofolate deformylase; Reviewed; Region: PRK13011 216591028868 N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875 216591028869 Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648 216591028870 putative active site [active] 216591028871 putative substrate binding site [chemical binding]; other site 216591028872 putative cosubstrate binding site; other site 216591028873 catalytic site [active] 216591028874 HMMPfam hit to PF00551, Formyl transferase, score 1.1e-28 216591028875 Amino acid permease; Region: AA_permease_2; pfam13520 216591028876 12 probable transmembrane helices predicted for BCAM2316 by TMHMM2.0 at aa 36-58, 62-84, 114-136, 163-185, 198-217, 248-270, 291-313, 336-358, 414-436, 451-473, 480-502 and 528-550 216591028877 HMMPfam hit to PF00324, Amino acid permease, score 0.00094 216591028878 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028879 Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069 216591028880 ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113 216591028881 HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 4e-88 216591028882 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018 216591028883 Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215 216591028884 FAD binding pocket [chemical binding]; other site 216591028885 FAD binding motif [chemical binding]; other site 216591028886 phosphate binding motif [ion binding]; other site 216591028887 beta-alpha-beta structure motif; other site 216591028888 NAD binding pocket [chemical binding]; other site 216591028889 Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633 216591028890 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591028891 catalytic loop [active] 216591028892 iron binding site [ion binding]; other site 216591028893 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 3.3e-17 216591028894 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591028895 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 1.5e-12 216591028896 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 7.7e-24 216591028897 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 216591028898 Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469 216591028899 [2Fe-2S] cluster binding site [ion binding]; other site 216591028900 C-terminal catalytic domain of GbcA (glycine betaine catabolism A) from Pseudomonas aeruginosa PAO1 and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_GbcA-like; cd08884 216591028901 putative alpha subunit interface [polypeptide binding]; other site 216591028902 putative active site [active] 216591028903 putative substrate binding site [chemical binding]; other site 216591028904 Fe binding site [ion binding]; other site 216591028905 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591028906 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 1.4e-24 216591028907 Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide; Region: AANH_like; cl00292 216591028908 Electron transfer flavoprotein domain; Region: ETF; pfam01012 216591028909 HMMPfam hit to PF01012, Electron transfer flavoprotein domain, score 0.00034 216591028910 Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025 216591028911 Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766 216591028912 HMMPfam hit to PF00766, Electron transfer flavoprotein FAD-binding, score 3.1e-31 216591028913 Domain of unknown function (DUF3483); Region: DUF3483; pfam11982 216591028914 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 216591028915 4Fe-4S binding domain; Region: Fer4; cl02805 216591028916 Cysteine-rich domain; Region: CCG; pfam02754 216591028917 Cysteine-rich domain; Region: CCG; pfam02754 216591028918 PS01047 Heavy-metal-associated domain. 216591028919 HMMPfam hit to PF02754, Cysteine-rich domain, score 3.5e-15 216591028920 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591028921 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0014 216591028922 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591028923 6 probable transmembrane helices predicted for BCAM2322 by TMHMM2.0 at aa 5-22, 29-48, 71-93, 100-116, 131-153 and 160-182 216591028924 mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997 216591028925 Old yellow enzyme (OYE)-related FMN binding domain, group 3. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_3_FMN; cd04734 216591028926 putative active site [active] 216591028927 putative FMN binding site [chemical binding]; other site 216591028928 putative substrate binding site [chemical binding]; other site 216591028929 putative catalytic residue [active] 216591028930 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 216591028931 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoredu, score 9.9e-06 216591028932 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoredu, score 0.0039 216591028933 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 7.3e-66 216591028934 The V4R (vinyl 4 reductase) domain is a predicted small molecular binding domain, that may bind to hydrocarbons; Region: V4R; smart00989 216591028935 HMMPfam hit to PF02830, V4R domain, score 5e-11 216591028936 Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355 216591028937 renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301 216591028938 active site 216591028939 dimer interface [polypeptide binding]; other site 216591028940 HMMPfam hit to PF01244, Membrane dipeptidase (Peptidase family, score 4.4e-148 216591028941 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028942 serine hydroxymethyltransferase; Reviewed; Region: PRK13034 216591028943 Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378 216591028944 dimer interface [polypeptide binding]; other site 216591028945 active site 216591028946 glycine-pyridoxal phosphate binding site [chemical binding]; other site 216591028947 folate binding site [chemical binding]; other site 216591028948 HMMPfam hit to PF00464, Serine hydroxymethyltransferase, score 8.9e-250 216591028949 PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 216591028950 PS00213 Lipocalin signature. 216591028951 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591028952 AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136 216591028953 conserved cys residue [active] 216591028954 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591028955 HMMPfam hit to PF01965, DJ-1/PfpI family, score 1.2e-06 216591028956 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.1e-09 216591028957 Predicted helix-turn-helix motif with score 2286.000, SD 6.97 at aa 264-285, sequence LSREELARLANMSQRQLQRLFR 216591028958 PS00041 Bacterial regulatory proteins, araC family signature. 216591028959 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 9.7e-06 216591028960 Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823 216591028961 F5/8 type C domain; Region: F5_F8_type_C; pfam00754 216591028962 sugar binding site [chemical binding]; other site 216591028963 HMMPfam hit to PF00754, F5/8 type C domain, score 5e-27 216591028964 1 probable transmembrane helix predicted for BCAM2328 by TMHMM2.0 at aa 7-29 216591028965 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591028966 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591028967 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591028968 DNA-binding site [nucleotide binding]; DNA binding site 216591028969 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591028970 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591028971 homodimer interface [polypeptide binding]; other site 216591028972 catalytic residue [active] 216591028973 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 5.5e-12 216591028974 HMMPfam hit to PF00155, Aminotransferase class I and II, score 3.3e-14 216591028975 Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956 216591028976 1 probable transmembrane helix predicted for BCAM2330 by TMHMM2.0 at aa 97-119 216591028977 EamA-like transporter family; Region: EamA; pfam00892 216591028978 EamA-like transporter family; Region: EamA; pfam00892 216591028979 10 probable transmembrane helices predicted for BCAM2331 by TMHMM2.0 at aa 7-24, 29-48, 61-83, 93-112, 119-138, 143-162, 175-197, 207-229, 236-255 and 260-282 216591028980 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.2e-17 216591028981 HMMPfam hit to PF03151, Triose-phosphate Transporter family, score 0.0015 216591028982 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.8e-21 216591028983 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591028984 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591028985 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591028986 dimerization interface [polypeptide binding]; other site 216591028987 substrate binding pocket [chemical binding]; other site 216591028988 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.1e-29 216591028989 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.1e-20 216591028990 PS00044 Bacterial regulatory proteins, lysR family signature. 216591028991 Predicted helix-turn-helix motif with score 2059.000, SD 6.20 at aa 20-41, sequence GSMKQAADLLCISPGAVSQHVR 216591028992 formaldehyde dehydrogenase, glutathione-independent; Region: fdhA_non_GSH; TIGR02819 216591028993 Pseudomonas putida aldehyde-dismutating formaldehyde dehydrogenase (PFDH); Region: PFDH_like; cd08282 216591028994 NAD binding site [chemical binding]; other site 216591028995 catalytic Zn binding site [ion binding]; other site 216591028996 structural Zn binding site [ion binding]; other site 216591028997 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 7.5e-15 216591028998 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 4.8e-39 216591028999 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591029000 multidrug efflux system protein EmrA; Provisional; Region: PRK15136 216591029001 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591029002 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.2e-50 216591029003 1 probable transmembrane helix predicted for BCAM2334 by TMHMM2.0 at aa 31-50 216591029004 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591029005 HMMPfam hit to PF02321, Outer membrane efflux protein, score 7.6e-27 216591029006 HMMPfam hit to PF02321, Outer membrane efflux protein, score 8.3e-13 216591029007 1 probable transmembrane helix predicted for BCAM2335 by TMHMM2.0 at aa 19-41 216591029008 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029009 RfbF is a putative dTDP-rhamnosyl transferase; Region: GT2_RfbF_like; cd02526 216591029010 Ligand binding site; other site 216591029011 L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556 216591029012 PS00215 Mitochondrial energy transfer proteins signature. 216591029013 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591029014 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029015 putative substrate translocation pore; other site 216591029016 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029017 12 probable transmembrane helices predicted for BCAM2337 by TMHMM2.0 at aa 75-97, 104-126, 130-152, 164-186, 191-213, 220-242, 257-275, 296-318, 328-350, 357-374, 384-406 and 504-521 216591029018 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.7e-53 216591029019 This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784 216591029020 active site 216591029021 TDP-binding site; other site 216591029022 acceptor substrate-binding pocket; other site 216591029023 HMMPfam hit to PF00201, UDP-glucoronosyl and UDP-glucosyl tra, score 0.00094 216591029024 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029025 HMMPfam hit to PF03033, Glycosyltransferase family, score 2.1e-12 216591029026 Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020 216591029027 HMMPfam hit to PF04140, Isoprenylcysteine carboxyl methyltransferase, score 4.6e-07 216591029028 4 probable transmembrane helices predicted for BCAM2339 by TMHMM2.0 at aa 4-21, 42-64, 74-96 and 117-139 216591029029 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591029030 transcriptional regulator BetI; Validated; Region: PRK00767 216591029031 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591029032 Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977 216591029033 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 4.2e-12 216591029034 PS01081 Bacterial regulatory proteins, tetR family signature. 216591029035 Predicted helix-turn-helix motif with score 1629.000, SD 4.74 at aa 30-51, sequence TTLASVAQRANISTGIVSHYFG 216591029036 betaine aldehyde dehydrogenase; Provisional; Region: PRK13252 216591029037 NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090 216591029038 tetrameric interface [polypeptide binding]; other site 216591029039 NAD binding site [chemical binding]; other site 216591029040 catalytic residues [active] 216591029041 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.8e-254 216591029042 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591029043 PS00070 Aldehyde dehydrogenases cysteine active site. 216591029044 choline dehydrogenase; Validated; Region: PRK02106 216591029045 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 216591029046 HMMPfam hit to PF00732, GMC oxidoreductase, score 8.6e-150 216591029047 PS00623 GMC oxidoreductases signature 1. 216591029048 PS00624 GMC oxidoreductases signature 2. 216591029049 HMMPfam hit to PF05199, GMC oxidoreductase, score 4.3e-68 216591029050 Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047 216591029051 HMMPfam hit to PF03922, OmpW family, score 1e-11 216591029052 Protein of unknown function (DUF2957); Region: DUF2957; pfam11170 216591029053 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029054 Protein of unknown function (DUF2957); Region: DUF2957; pfam11170 216591029055 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029056 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029057 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029058 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029059 Cupin domain; Region: Cupin_2; cl17218 216591029060 HMMPfam hit to PF07883, Cupin domain, score 0.00072 216591029061 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 216591029062 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 216591029063 Walker A/P-loop; other site 216591029064 ATP binding site [chemical binding]; other site 216591029065 Q-loop/lid; other site 216591029066 ABC transporter signature motif; other site 216591029067 Walker B; other site 216591029068 D-loop; other site 216591029069 H-loop/switch region; other site 216591029070 HMMPfam hit to PF00005, ABC transporter score 4.3e-54 216591029071 PS00017 ATP/GTP-binding site motif A (P-loop). 216591029072 PS00211 ABC transporters family signature. 216591029073 ABC-2 type transporter; Region: ABC2_membrane; cl17235 216591029074 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 216591029075 HMMPfam hit to PF01061, ABC-2 type transporter score 1.2e-40 216591029076 7 probable transmembrane helices predicted for BCAM2351 by TMHMM2.0 at aa 21-43, 58-80, 115-134, 138-160, 167-189, 194-216 and 223-245 216591029077 PS00890 ABC-2 type transport system integral membrane proteins signature. 216591029078 benzoate transport; Region: 2A0115; TIGR00895 216591029079 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029080 putative substrate translocation pore; other site 216591029081 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029082 HMMPfam hit to PF00083, Sugar (and other) transporter score 6.1e-22 216591029083 11 probable transmembrane helices predicted for BCAM2352 by TMHMM2.0 at aa 26-48, 60-82, 97-119, 150-172, 176-195, 268-290, 300-322, 329-351, 355-377, 398-417 and 421-443 216591029084 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 8.9e-53 216591029085 PS00216 Sugar transport proteins signature 1. 216591029086 PS00217 Sugar transport proteins signature 2. 216591029087 PS00216 Sugar transport proteins signature 1. 216591029088 PAS fold; Region: PAS_4; pfam08448 216591029089 Septum formation initiator; Region: DivIC; cl17659 216591029090 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591029091 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591029092 dimer interface [polypeptide binding]; other site 216591029093 phosphorylation site [posttranslational modification] 216591029094 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591029095 ATP binding site [chemical binding]; other site 216591029096 G-X-G motif; other site 216591029097 FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784 216591029098 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591029099 active site 216591029100 phosphorylation site [posttranslational modification] 216591029101 intermolecular recognition site; other site 216591029102 dimerization interface [polypeptide binding]; other site 216591029103 HMMPfam hit to PF08448, PAS fold, score 0.0016 216591029104 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.0013 216591029105 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 1.2e-34 216591029106 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.6e-14 216591029107 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3795 216591029108 HMMPfam hit to PF04946, DGPF domain, score 1.2e-54 216591029109 DinB superfamily; Region: DinB_2; pfam12867 216591029110 PS00018 EF-hand calcium-binding domain. 216591029111 Lipase (class 2); Region: Lipase_2; pfam01674 216591029112 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695 216591029113 Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303 216591029114 catalytic site [active] 216591029115 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 4.4e-07 216591029116 PS00120 Lipases, serine active site. 216591029117 Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819 216591029118 Predicted esterase [General function prediction only]; Region: COG0627 216591029119 1 probable transmembrane helix predicted for BCAM2358 by TMHMM2.0 at aa 11-33 216591029120 HMMPfam hit to PF00756, Putative esterase, score 3.2e-32 216591029121 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 216591029122 PS00017 ATP/GTP-binding site motif A (P-loop). 216591029123 Predicted helix-turn-helix motif with score 1660.000, SD 4.84 at aa 22-43, sequence RSSSEIARLSGVSQPTVSRLRL 216591029124 pyrroloquinoline quinone biosynthesis protein PqqE; Provisional; Region: PRK05301 216591029125 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591029126 FeS/SAM binding site; other site 216591029127 radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085 216591029128 HMMPfam hit to PF04055, Radical SAM superfamily, score 6e-27 216591029129 coenzyme PQQ biosynthesis protein PqqD; Region: PQQ_PqqD; TIGR03859 216591029130 HMMPfam hit to PF05402, Coenzyme PQQ synthesis protein D (PqqD), score 1.5e-12 216591029131 pyrroloquinoline quinone biosynthesis protein PqqC; Provisional; Region: PRK05157 216591029132 HMMPfam hit to PF03070, TENA/THI-4/PQQC family, score 2.2e-64 216591029133 pyrroloquinoline quinone biosynthesis protein PqqB; Provisional; Region: PRK05184 216591029134 coenzyme PQQ biosynthesis protein B; Region: PQQ_syn_pqqB; TIGR02108 216591029135 coenzyme PQQ synthesis protein PqqA; Provisional; Region: pqqA; PRK00284 216591029136 HMMPfam hit to PF08042, PqqA family, score 6e-09 216591029137 Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284 216591029138 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591029139 Walker A motif; other site 216591029140 ATP binding site [chemical binding]; other site 216591029141 Walker B motif; other site 216591029142 arginine finger; other site 216591029143 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591029144 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 2.7e-10 216591029145 Predicted helix-turn-helix motif with score 1770.000, SD 5.22 at aa 643-664, sequence GNVSAAARALGVSRNTIYRKMP 216591029146 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3.7e-119 216591029147 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591029148 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591029149 HMMPfam hit to PF01590, GAF domain, score 3.5e-10 216591029150 proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249 216591029151 homoserine O-acetyltransferase; Provisional; Region: metX; cl17114 216591029152 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 3.7e-23 216591029153 Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629 216591029154 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591029155 N-terminal plug; other site 216591029156 ligand-binding site [chemical binding]; other site 216591029157 HMMPfam hit to PF00593, TonB dependent receptor, score 6.7e-32 216591029158 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.6e-15 216591029159 PQQ-dependent dehydrogenase, methanol/ethanol family; Region: PQQ_enz_alc_DH; TIGR03075 216591029160 Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); Region: PQQ_ADH_I; cd10277 216591029161 dimer interface [polypeptide binding]; other site 216591029162 Trp docking motif [polypeptide binding]; other site 216591029163 active site 216591029164 1 probable transmembrane helix predicted for BCAM2368 by TMHMM2.0 at aa 13-35 216591029165 HMMPfam hit to PF01011, PQQ enzyme repeat, score 2.9e-06 216591029166 HMMPfam hit to PF01011, PQQ enzyme repeat, score 1.5e-05 216591029167 Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062 216591029168 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591029169 membrane-bound complex binding site; other site 216591029170 hinge residues; other site 216591029171 Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442 216591029172 PS00190 Cytochrome c family heme-binding site signature. 216591029173 High potential iron-sulfur protein; Region: HIPIP; pfam01355 216591029174 HMMPfam hit to PF01355, High potential iron-sulfur protein, score 5.3e-21 216591029175 PS00596 High potential iron-sulfur proteins signature. 216591029176 RNA polymerase sigma factor RpoD; Validated; Region: PRK05658 216591029177 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 216591029178 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591029179 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 216591029180 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591029181 DNA binding residues [nucleotide binding] 216591029182 HMMPfam hit to PF03979, Sigma-70 factor, region, score 3.5e-05 216591029183 HMMPfam hit to PF00140, Sigma-70 factor, region, score 1.3e-10 216591029184 HMMPfam hit to PF04542, Sigma-70 region, score 1.8e-27 216591029185 PS00715 Sigma-70 factors family signature 1. 216591029186 HMMPfam hit to PF04539, Sigma-70 region, score 1.3e-13 216591029187 HMMPfam hit to PF04545, Sigma-70, region, score 6.6e-15 216591029188 Predicted helix-turn-helix motif with score 1497.000, SD 4.29 at aa 587-608, sequence YSLREIGRQLNLSAERVRQLEV 216591029189 PS00716 Sigma-70 factors family signature 2. 216591029190 acetyl-CoA synthetase; Provisional; Region: PRK00174 216591029191 Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966 216591029192 active site 216591029193 CoA binding site [chemical binding]; other site 216591029194 acyl-activating enzyme (AAE) consensus motif; other site 216591029195 AMP binding site [chemical binding]; other site 216591029196 acetate binding site [chemical binding]; other site 216591029197 HMMPfam hit to PF00501, AMP-binding enzyme, score 4.2e-135 216591029198 PS00455 Putative AMP-binding domain signature. 216591029199 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591029200 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591029201 trimer interface [polypeptide binding]; other site 216591029202 eyelet of channel; other site 216591029203 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591029204 dimer interface [polypeptide binding]; other site 216591029205 Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015 216591029206 putative CheW interface [polypeptide binding]; other site 216591029207 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 1.2e-08 216591029208 lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212 216591029209 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 216591029210 FtsX-like permease family; Region: FtsX; pfam02687 216591029211 4 probable transmembrane helices predicted for BCAM2376 by TMHMM2.0 at aa 30-52, 279-301, 334-356 and 383-405 216591029212 HMMPfam hit to PF02687, Predicted permease, score 5.1e-43 216591029213 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029214 X-Pro dipeptidyl-peptidase (S15 family); Region: Peptidase_S15; pfam02129 216591029215 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 216591029216 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530 216591029217 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029218 HMMPfam hit to PF02129, X-Pro dipeptidyl-peptidase (S15 family), score 5e-92 216591029219 PS00017 ATP/GTP-binding site motif A (P-loop). 216591029220 HMMPfam hit to PF08530, X-Pro dipeptidyl-peptidase C-terminal n, score 3.5e-54 216591029221 Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883 216591029222 nudix motif; other site 216591029223 HMMPfam hit to PF00293, NUDIX domain, score 1.6e-15 216591029224 PS00893 mutT domain signature. 216591029225 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 216591029226 Hydroxy(phenyl)pyruvate Reductase, D-isomer-specific 2-hydroxyacid-related dehydrogenase; Region: HPPR; cd12156 216591029227 putative ligand binding site [chemical binding]; other site 216591029228 NAD binding site [chemical binding]; other site 216591029229 catalytic site [active] 216591029230 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 3.2e-19 216591029231 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 1.7e-71 216591029232 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 216591029233 ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891 216591029234 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732 216591029235 HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 2e-69 216591029236 ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174 216591029237 11 probable transmembrane helices predicted for BCAM2382 by TMHMM2.0 at aa 17-36, 51-73, 80-102, 117-139, 146-168, 188-210, 223-245, 255-277, 308-327, 332-354 and 361-383 216591029238 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.2e-16 216591029239 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029240 ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125 216591029241 ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295 216591029242 Walker A/P-loop; other site 216591029243 ATP binding site [chemical binding]; other site 216591029244 Q-loop/lid; other site 216591029245 ABC transporter signature motif; other site 216591029246 Walker B; other site 216591029247 D-loop; other site 216591029248 H-loop/switch region; other site 216591029249 HMMPfam hit to PF00005, ABC transporter score 9.5e-56 216591029250 PS00017 ATP/GTP-binding site motif A (P-loop). 216591029251 PS00211 ABC transporters family signature. 216591029252 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591029253 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591029254 ABC-ATPase subunit interface; other site 216591029255 5 probable transmembrane helices predicted for BCAM2384 by TMHMM2.0 at aa 15-37, 63-85, 117-139, 187-209 and 224-246 216591029256 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 216591029257 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.4e-20 216591029258 Rifampin ADP-ribosyl transferase; Region: Arr-ms; pfam12120 216591029259 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 216591029260 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591029261 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591029262 catalytic residue [active] 216591029263 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 2.9e-13 216591029264 Dihydroneopterin aldolase [Coenzyme metabolism]; Region: FolB; COG1539 216591029265 active site 216591029266 Sarcosine oxidase gamma subunit [Amino acid transport and metabolism]; Region: COG4583 216591029267 HMMPfam hit to PF04268, Sarcosine oxidase, gamma subunit family, score 1.3e-37 216591029268 sarcosine oxidase, alpha subunit family, heterotetrameric form; Region: soxA; TIGR01372 216591029269 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510 216591029270 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591029271 Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669 216591029272 HMMPfam hit to PF01571, Glycine cleavage T-protein (aminomethyl t, score 1.7e-80 216591029273 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 8.3e-05 216591029274 Sarcosine oxidase delta subunit [Amino acid transport and metabolism]; Region: SoxD; COG4311 216591029275 HMMPfam hit to PF04267, Sarcosine oxidase, delta subunit family, score 1.8e-39 216591029276 sarcosine oxidase, beta subunit family, heterotetrameric form; Region: soxB; TIGR01373 216591029277 hydroxyglutarate oxidase; Provisional; Region: PRK11728 216591029278 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 5.8e-88 216591029279 L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720 216591029280 Serine dehydratase beta chain; Region: SDH_beta; pfam03315 216591029281 Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313 216591029282 HMMPfam hit to PF03313, Serine dehydratase alpha chain, score 3.7e-167 216591029283 HMMPfam hit to PF03315, Serine dehydratase beta chain, score 5.1e-59 216591029284 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029285 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591029286 AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136 216591029287 conserved cys residue [active] 216591029288 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591029289 HMMPfam hit to PF01965, DJ-1/PfpI family, score 5e-06 216591029290 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 2.3e-06 216591029291 Predicted helix-turn-helix motif with score 1844.000, SD 5.47 at aa 250-271, sequence LPLEELACKLDLSTRQLERLFK 216591029292 PS00041 Bacterial regulatory proteins, araC family signature. 216591029293 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 2.1e-10 216591029294 Transcriptional regulators [Transcription]; Region: FadR; COG2186 216591029295 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591029296 DNA-binding site [nucleotide binding]; DNA binding site 216591029297 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 216591029298 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 7.4e-22 216591029299 HMMPfam hit to PF08279, HTH domain, score 0.0028 216591029300 PS00043 Bacterial regulatory proteins, gntR family signature. 216591029301 Predicted helix-turn-helix motif with score 1129.000, SD 3.03 at aa 34-55, sequence PTEAVLAQEFGVSRTVIREAIS 216591029302 HMMPfam hit to PF07729, FCD domain, score 1.1e-36 216591029303 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084 216591029304 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 216591029305 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 4.1e-53 216591029306 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395 216591029307 HMMPfam hit to PF07005, Protein of unknown function, DUF1537, score 7.3e-103 216591029308 putative aldolase; Validated; Region: PRK08130 216591029309 intersubunit interface [polypeptide binding]; other site 216591029310 active site 216591029311 Zn2+ binding site [ion binding]; other site 216591029312 HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 2.3e-41 216591029313 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029314 D-galactonate transporter; Region: 2A0114; TIGR00893 216591029315 putative substrate translocation pore; other site 216591029316 HMMPfam hit to PF00083, Sugar (and other) transporter score 0.00018 216591029317 12 probable transmembrane helices predicted for BCAM2398 by TMHMM2.0 at aa 28-47, 62-84, 97-116, 122-144, 156-178, 191-213, 259-281, 291-313, 326-343, 347-369, 376-398 and 413-435 216591029318 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4e-59 216591029319 Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622 216591029320 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 1.9e-48 216591029321 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 216591029322 Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238 216591029323 putative NAD(P) binding site [chemical binding]; other site 216591029324 active site 216591029325 putative substrate binding site [chemical binding]; other site 216591029326 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.3e-06 216591029327 HMMPfam hit to PF04321, RmlD substrate binding domain, score 2.9e-06 216591029328 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.00084 216591029329 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 6.8e-18 216591029330 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 6.2e-08 216591029331 HMMPfam hit to PF07993, Male sterility protein, score 2.3e-09 216591029332 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591029333 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591029334 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555 216591029335 HMMPfam hit to PF05118, Aspartyl/Asparaginyl beta-hydroxylase, score 5.9e-24 216591029336 Ubiquitin-like proteins; Region: UBQ; cl00155 216591029337 charged pocket; other site 216591029338 hydrophobic patch; other site 216591029339 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.93 216591029340 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 9.6 216591029341 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.51 216591029342 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 20 216591029343 HMMPfam hit to PF02012, BNR/Asp-box repeat, score 4.5 216591029344 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591029345 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591029346 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591029347 dimerization interface [polypeptide binding]; other site 216591029348 HMMPfam hit to PF03466, LysR substrate binding domain, score 7.4e-25 216591029349 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.4e-20 216591029350 PS00044 Bacterial regulatory proteins, lysR family signature. 216591029351 Predicted helix-turn-helix motif with score 1862.000, SD 5.53 at aa 20-41, sequence GTFKAAADELSVTPAAVSHQIK 216591029352 Bacterial Transmembrane Pair family; Region: BTP; pfam05232 216591029353 Bacterial Transmembrane Pair family; Region: BTP; pfam05232 216591029354 HMMPfam hit to PF05232, Bacterial Transmembrane Pair family, score 4.2e-13 216591029355 4 probable transmembrane helices predicted for BCAM2405 by TMHMM2.0 at aa 12-30, 34-56, 77-96 and 106-128 216591029356 HMMPfam hit to PF05232, Bacterial Transmembrane Pair family, score 1.7e-28 216591029357 Predicted membrane protein [Function unknown]; Region: COG2860 216591029358 UPF0126 domain; Region: UPF0126; pfam03458 216591029359 HMMPfam hit to PF03458, UPF0126 domain, score 2e-24 216591029360 7 probable transmembrane helices predicted for BCAM2406 by TMHMM2.0 at aa 39-61, 66-88, 101-120, 125-144, 151-170, 175-197 and 204-226 216591029361 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029362 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029363 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029364 HMMPfam hit to PF03458, UPF0126 domain, score 3.7e-23 216591029365 ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113 216591029366 choline ABC transporter, periplasmic binding protein; Region: ABC_choline_bnd; TIGR03414 216591029367 HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 8.1e-68 216591029368 1 probable transmembrane helix predicted for BCAM2407 by TMHMM2.0 at aa 5-24 216591029369 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591029370 AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136 216591029371 conserved cys residue [active] 216591029372 Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188 216591029373 metal binding site [ion binding]; metal-binding site 216591029374 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591029375 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.6e-07 216591029376 PS00041 Bacterial regulatory proteins, araC family signature. 216591029377 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 2.2e-08 216591029378 Predicted helix-turn-helix motif with score 1808.000, SD 5.34 at aa 245-266, sequence LSLEELARLVRLSQRHLQRMFK 216591029379 HMMPfam hit to PF01965, DJ-1/PfpI family, score 5.3e-10 216591029380 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591029381 dimer interface [polypeptide binding]; other site 216591029382 conserved gate region; other site 216591029383 putative PBP binding loops; other site 216591029384 ABC-ATPase subunit interface; other site 216591029385 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 7.2e-32 216591029386 5 probable transmembrane helices predicted for BCAM2409 by TMHMM2.0 at aa 44-66, 68-85, 90-112, 132-154 and 213-235 216591029387 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591029388 ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175 216591029389 ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294 216591029390 Walker A/P-loop; other site 216591029391 ATP binding site [chemical binding]; other site 216591029392 Q-loop/lid; other site 216591029393 ABC transporter signature motif; other site 216591029394 Walker B; other site 216591029395 D-loop; other site 216591029396 H-loop/switch region; other site 216591029397 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354 216591029398 HMMPfam hit to PF00005, ABC transporter score 2.2e-65 216591029399 PS00211 ABC transporters family signature. 216591029400 PS00017 ATP/GTP-binding site motif A (P-loop). 216591029401 Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101 216591029402 32 probable transmembrane helices predicted for BCAM2411 by TMHMM2.0 at aa 2-19, 23-42, 205-227, 237-259, 266-285, 289-311, 318-335, 345-362, 367-389, 399-416, 429-446, 450-472, 479-501, 505-522, 527-549, 564-583, 590-612, 632-650, 657-679, 684-706, 719-741, 761-783, 795-817, 827-849, 862-884, 899-921, 926-948, 963-982, 994-1016, 1036-1058, 1065-1084 and 1094-1113 216591029403 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591029404 Protein of unknown function (DUF3999); Region: DUF3999; pfam13163 216591029405 1 probable transmembrane helix predicted for BCAM2412 by TMHMM2.0 at aa 419-441 216591029406 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591029407 Coenzyme A binding pocket [chemical binding]; other site 216591029408 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.2e-16 216591029409 NIPSNAP; Region: NIPSNAP; pfam07978 216591029410 HMMPfam hit to PF07978, NIPSNAP, score 5.8e-34 216591029411 Predicted flavoprotein [General function prediction only]; Region: COG0431 216591029412 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591029413 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 2.6e-10 216591029414 Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865 216591029415 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 216591029416 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591029417 trimer interface [polypeptide binding]; other site 216591029418 YadA-like C-terminal region; Region: YadA; pfam03895 216591029419 1 probable transmembrane helix predicted for BCAM2418 by TMHMM2.0 at aa 33-55 216591029420 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029421 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029422 HMMPfam hit to PF05658, Hep_Hag, score 2.9e-05 216591029423 HMMPfam hit to PF05658, Hep_Hag, score 1.1 216591029424 HMMPfam hit to PF05658, Hep_Hag, score 0.0016 216591029425 HMMPfam hit to PF05658, Hep_Hag, score 1.5 216591029426 HMMPfam hit to PF05658, Hep_Hag, score 1.4 216591029427 HMMPfam hit to PF05658, Hep_Hag, score 1.1 216591029428 HMMPfam hit to PF05658, Hep_Hag, score 1.3e-05 216591029429 HMMPfam hit to PF05662, Haemagglutinin, score 3.2e-07 216591029430 HMMPfam hit to PF05658, Hep_Hag, score 0.00056 216591029431 HMMPfam hit to PF05662, Haemagglutinin, score 8.6e-08 216591029432 HMMPfam hit to PF05658, Hep_Hag, score 0.0014 216591029433 HMMPfam hit to PF05658, Hep_Hag, score 0.027 216591029434 HMMPfam hit to PF05658, Hep_Hag, score 0.00012 216591029435 HMMPfam hit to PF05658, Hep_Hag, score 0.0011 216591029436 HMMPfam hit to PF05658, Hep_Hag, score 0.13 216591029437 HMMPfam hit to PF05658, Hep_Hag, score 2.3e-05 216591029438 HMMPfam hit to PF05662, Haemagglutinin, score 7.1e-09 216591029439 HMMPfam hit to PF05662, Haemagglutinin, score 1.1e-07 216591029440 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 216591029441 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591029442 ligand binding site [chemical binding]; other site 216591029443 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029444 HMMPfam hit to PF00691, OmpA family, score 2.6e-25 216591029445 Protein of unknown function (DUF2827); Region: DUF2827; pfam10933 216591029446 Protein of unknown function (DUF2827); Region: DUF2827; pfam10933 216591029447 Protein of unknown function (DUF4019); Region: DUF4019; pfam13211 216591029448 Protein of unknown function (DUF2827); Region: DUF2827; pfam10933 216591029449 methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444 216591029450 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029451 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 216591029452 HMMPfam hit to PF00563, EAL domain, score 8.7e-14 216591029453 Protein of unknown function (DUF2827); Region: DUF2827; pfam10933 216591029454 galactosyl transferase GMA12/MNN10 family; Region: Glyco_transf_34; cl05288 216591029455 phospholipase C, phosphocholine-specific, Pseudomonas-type; Region: PC_PLC; TIGR03396 216591029456 Phosphoesterase family; Region: Phosphoesterase; pfam04185 216591029457 Domain of unknown function (DUF756); Region: DUF756; pfam05506 216591029458 Domain of unknown function (DUF756); Region: DUF756; pfam05506 216591029459 HMMPfam hit to PF05506, Domain of unknown function (DUF756), score 1.1e-19 216591029460 HMMPfam hit to PF05506, Domain of unknown function (DUF756), score 8e-26 216591029461 HMMPfam hit to PF04185, Phosphoesterase family, score 1.9e-144 216591029462 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029463 Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770 216591029464 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 216591029465 ATP-grasp domain; Region: ATP-grasp_4; cl17255 216591029466 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 216591029467 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 216591029468 carboxyltransferase (CT) interaction site; other site 216591029469 biotinylation site [posttranslational modification]; other site 216591029470 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 5.8e-22 216591029471 PS00188 Biotin-requiring enzymes attachment site. 216591029472 HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain, score 1.4e-44 216591029473 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591029474 HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 6.1e-102 216591029475 HMMPfam hit to PF02655, ATP-grasp domain, score 0.0018 216591029476 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 216591029477 HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase,, score 0.00016 216591029478 HMMPfam hit to PF02222, ATP-grasp domain, score 0.003 216591029479 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 216591029480 HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 1.8e-46 216591029481 enoyl-CoA hydratase; Provisional; Region: PRK05995 216591029482 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591029483 substrate binding site [chemical binding]; other site 216591029484 oxyanion hole (OAH) forming residues; other site 216591029485 trimer interface [polypeptide binding]; other site 216591029486 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 2.4e-32 216591029487 3-methylcrotonyl-CoA carboxylase, beta chain; Region: PLN02820 216591029488 malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682 216591029489 HMMPfam hit to PF01039, Carboxyl transferase domain, score 2.5e-219 216591029490 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029491 isovaleryl-CoA dehydrogenase; Region: PLN02519 216591029492 Isovaleryl-CoA dehydrogenase; Region: IVD; cd01156 216591029493 substrate binding site [chemical binding]; other site 216591029494 FAD binding site [chemical binding]; other site 216591029495 catalytic base [active] 216591029496 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 2.1e-54 216591029497 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 3.1e-10 216591029498 PS00073 Acyl-CoA dehydrogenases signature 2. 216591029499 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029500 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 1e-27 216591029501 PS00072 Acyl-CoA dehydrogenases signature 1. 216591029502 HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal doma, score 1.8e-43 216591029503 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591029504 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591029505 YsiA-like protein, C-terminal region; Region: TetR_C_4; pfam08359 216591029506 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.2e-15 216591029507 Predicted helix-turn-helix motif with score 1804.000, SD 5.33 at aa 20-41, sequence ATAAEIAQRVGVSEATVFSYFR 216591029508 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 216591029509 MarR family; Region: MarR; pfam01047 216591029510 HMMPfam hit to PF01047, MarR family, score 1.8e-13 216591029511 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 216591029512 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938 216591029513 iron-sulfur cluster [ion binding]; other site 216591029514 [2Fe-2S] cluster binding site [ion binding]; other site 216591029515 C-terminal catalytic domain of the oxygenase alpha subunit of dicamba O-demethylase and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_DMO-like; cd08878 216591029516 alpha subunit interface [polypeptide binding]; other site 216591029517 active site 216591029518 substrate binding site [chemical binding]; other site 216591029519 Fe binding site [ion binding]; other site 216591029520 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 3.3e-21 216591029521 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018 216591029522 Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185 216591029523 FMN-binding pocket [chemical binding]; other site 216591029524 flavin binding motif; other site 216591029525 phosphate binding motif [ion binding]; other site 216591029526 beta-alpha-beta structure motif; other site 216591029527 NAD binding pocket [chemical binding]; other site 216591029528 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591029529 catalytic loop [active] 216591029530 iron binding site [ion binding]; other site 216591029531 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 4.1e-07 216591029532 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 3.4e-09 216591029533 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 5.2e-18 216591029534 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591029535 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029536 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 216591029537 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591029538 N-terminal plug; other site 216591029539 ligand-binding site [chemical binding]; other site 216591029540 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.9e-21 216591029541 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591029542 HMMPfam hit to PF00593, TonB dependent receptor, score 9.6e-26 216591029543 PS00213 Lipocalin signature. 216591029544 Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531 216591029545 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591029546 substrate binding pocket [chemical binding]; other site 216591029547 membrane-bound complex binding site; other site 216591029548 hinge residues; other site 216591029549 1 probable transmembrane helix predicted for BCAM2441 by TMHMM2.0 at aa 25-42 216591029550 Cytochrome c; Region: Cytochrom_C; cl11414 216591029551 Cytochrome c; Region: Cytochrom_C; cl11414 216591029552 HMMPfam hit to PF00034, Cytochrome c, score 1.2e-09 216591029553 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029554 PS00190 Cytochrome c family heme-binding site signature. 216591029555 HMMPfam hit to PF00034, Cytochrome c, score 0.00021 216591029556 PS00190 Cytochrome c family heme-binding site signature. 216591029557 Cytochrome c [Energy production and conversion]; Region: COG3258 216591029558 Cytochrome c; Region: Cytochrom_C; pfam00034 216591029559 PS00190 Cytochrome c family heme-binding site signature. 216591029560 HMMPfam hit to PF00034, Cytochrome c, score 0.013 216591029561 PS00190 Cytochrome c family heme-binding site signature. 216591029562 SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450 216591029563 Glutathione-dependent formaldehyde-activating enzyme; Region: GFA; cl01553 216591029564 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591029565 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591029566 trimer interface [polypeptide binding]; other site 216591029567 eyelet of channel; other site 216591029568 HMMPfam hit to PF00267, Gram-negative porin, score 3.6e-07 216591029569 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591029570 6 probable transmembrane helices predicted for BCAM2447 by TMHMM2.0 at aa 5-27, 39-61, 71-93, 113-135, 150-172 and 185-204 216591029571 HMMPfam hit to PF01810, LysE type translocator, score 3.7e-30 216591029572 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 216591029573 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591029574 Coenzyme A binding pocket [chemical binding]; other site 216591029575 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.2e-14 216591029576 Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850 216591029577 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 216591029578 active site 216591029579 metal binding site [ion binding]; metal-binding site 216591029580 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 8.7e-22 216591029581 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591029582 TAP-like protein; Region: Abhydrolase_4; pfam08386 216591029583 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 0.00022 216591029584 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591029585 dimerization interface [polypeptide binding]; other site 216591029586 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591029587 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591029588 ATP binding site [chemical binding]; other site 216591029589 Mg2+ binding site [ion binding]; other site 216591029590 G-X-G motif; other site 216591029591 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 7.1e-38 216591029592 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.00031 216591029593 HMMPfam hit to PF00672, HAMP domain, score 4.4e-15 216591029594 2 probable transmembrane helices predicted for BCAM2451 by TMHMM2.0 at aa 13-35 and 155-177 216591029595 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029596 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591029597 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591029598 active site 216591029599 phosphorylation site [posttranslational modification] 216591029600 intermolecular recognition site; other site 216591029601 dimerization interface [polypeptide binding]; other site 216591029602 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591029603 DNA binding site [nucleotide binding] 216591029604 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 2.8e-17 216591029605 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.4e-41 216591029606 TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA...; Region: TlpA_like_DipZ_like; cd03012 216591029607 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591029608 catalytic residues [active] 216591029609 1 probable transmembrane helix predicted for BCAM2453 by TMHMM2.0 at aa 7-26 216591029610 HMMPfam hit to PF08534, Redoxin, score 1.3e-13 216591029611 Transcriptional regulator [Transcription]; Region: PaiB; COG2808 216591029612 HMMPfam hit to PF04299, Putative FMN-binding domain, score 2.1e-76 216591029613 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591029614 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591029615 DNA-binding site [nucleotide binding]; DNA binding site 216591029616 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591029617 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591029618 homodimer interface [polypeptide binding]; other site 216591029619 catalytic residue [active] 216591029620 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 2.6e-15 216591029621 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.1e-06 216591029622 Transglycosylase; Region: Transgly; pfam00912 216591029623 penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074 216591029624 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 216591029625 1 probable transmembrane helix predicted for BCAM2456 by TMHMM2.0 at aa 49-71 216591029626 HMMPfam hit to PF00912, Transglycosylase, score 2e-86 216591029627 PS00017 ATP/GTP-binding site motif A (P-loop). 216591029628 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 1.7e-30 216591029629 Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816 216591029630 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 216591029631 active site 216591029632 HMMPfam hit to PF00962, Adenosine/AMP deaminase, score 2.7e-38 216591029633 Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism]; Region: COG2252 216591029634 12 probable transmembrane helices predicted for BCAM2459 by TMHMM2.0 at aa 34-56, 69-91, 111-133, 140-162, 182-200, 207-229, 256-278, 298-320, 335-357, 364-381, 394-416 and 429-446 216591029635 HMMPfam hit to PF00916, Sulfate transporter family, score 0.0024 216591029636 HMMPfam hit to PF00860, Permease family, score 4.4e-09 216591029637 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029638 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591029639 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591029640 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591029641 dimerization interface [polypeptide binding]; other site 216591029642 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 9.1e-15 216591029643 Predicted helix-turn-helix motif with score 1376.000, SD 3.87 at aa 49-70, sequence RSFTQAAQALSLTQPALTASIR 216591029644 PS00044 Bacterial regulatory proteins, lysR family signature. 216591029645 HMMPfam hit to PF03466, LysR substrate binding domain, score 8.6e-31 216591029646 nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651 216591029647 active site 216591029648 tetramer interface [polypeptide binding]; other site 216591029649 HMMPfam hit to PF01156, Inosine-uridine preferring nucleoside hy, score 2.8e-92 216591029650 PS00017 ATP/GTP-binding site motif A (P-loop). 216591029651 PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 216591029652 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 216591029653 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591029654 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591029655 trimer interface [polypeptide binding]; other site 216591029656 eyelet of channel; other site 216591029657 HMMPfam hit to PF00267, Gram-negative porin, score 9.3e-05 216591029658 PS00017 ATP/GTP-binding site motif A (P-loop). 216591029659 benzoate transport; Region: 2A0115; TIGR00895 216591029660 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029661 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029662 HMMPfam hit to PF00083, Sugar (and other) transporter score 2.8e-07 216591029663 12 probable transmembrane helices predicted for BCAM2464 by TMHMM2.0 at aa 38-60, 82-104, 111-129, 139-158, 171-193, 203-220, 290-312, 322-343, 350-369, 374-396, 409-431 and 435-457 216591029664 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.1e-23 216591029665 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591029666 PS00217 Sugar transport proteins signature 2. 216591029667 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029668 PS01159 WW/rsp5/WWP domain signature. 216591029669 Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: COG3264 216591029670 Protein of unknown function (DUF3772); Region: DUF3772; pfam12607 216591029671 Mechanosensitive ion channel; Region: MS_channel; pfam00924 216591029672 11 probable transmembrane helices predicted for BCAM2465 by TMHMM2.0 at aa 21-43, 232-254, 275-297, 312-334, 346-368, 383-405, 426-448, 453-475, 513-535, 565-582 and 602-624 216591029673 HMMPfam hit to PF00924, Mechanosensitive ion channel, score 2.3e-47 216591029674 Group II intron - IBS3 216591029675 RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651 216591029676 Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078 216591029677 putative active site [active] 216591029678 putative NTP binding site [chemical binding]; other site 216591029679 putative nucleic acid binding site [nucleotide binding]; other site 216591029680 Group II intron, maturase-specific domain; Region: GIIM; pfam08388 216591029681 HMMPfam hit to PF08388, Group II intron, maturase-specific domain, score 2e-24 216591029682 HMMPfam hit to PF00078, Reverse transcriptase (RNA-dependent DNA pol, score 1.9e-57 216591029683 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591029684 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591029685 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591029686 HMMPfam hit to PF01548, Transposase, score 0.00086 216591029687 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 9.4e-37 216591029688 Group II intron - EBS3 216591029689 Group II intron - EBS1 216591029690 Group II intron - IBS1 216591029691 NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130 216591029692 aldehyde dehydrogenase family 7 member; Region: PLN02315 216591029693 tetrameric interface [polypeptide binding]; other site 216591029694 NAD binding site [chemical binding]; other site 216591029695 catalytic residues [active] 216591029696 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 6.7e-131 216591029697 lysine transporter; Provisional; Region: PRK10836 216591029698 HMMPfam hit to PF00324, Amino acid permease, score 5.6e-171 216591029699 12 probable transmembrane helices predicted for BCAM2469 by TMHMM2.0 at aa 34-56, 60-82, 102-124, 139-161, 168-190, 205-227, 254-276, 299-321, 356-375, 379-401, 425-442 and 457-479 216591029700 PS00218 Amino acid permeases signature. 216591029701 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591029702 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591029703 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 5.5e-80 216591029704 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591029705 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591029706 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 6.7e-15 216591029707 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 216591029708 Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502 216591029709 putative active site [active] 216591029710 catalytic site [active] 216591029711 Putative catalytic domain, repeat 2, of uncharacterized hypothetical proteins similar to Nuc, an endonuclease from Salmonella typhimurium; Region: PLDc_Nuc_like_unchar1_2; cd09173 216591029712 putative active site [active] 216591029713 catalytic site [active] 216591029714 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 0.055 216591029715 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 7.6 216591029716 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 216591029717 DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220 216591029718 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 216591029719 HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 7.6e-36 216591029720 HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 5.7e-18 216591029721 HMMPfam hit to PF08279, HTH domain, score 0.00038 216591029722 Predicted helix-turn-helix motif with score 1484.000, SD 4.24 at aa 20-41, sequence LSVAELVRSLDVSRETVRRDLN 216591029723 PS00894 Bacterial regulatory proteins, deoR family signature. 216591029724 10 probable transmembrane helices predicted for BCAM2475 by TMHMM2.0 at aa 2-24, 34-56, 63-85, 90-112, 121-143, 153-172, 185-204, 214-236, 243-265 and 269-286 216591029725 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 7.5e-11 216591029726 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.2e-08 216591029727 NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553 216591029728 NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171 216591029729 homodimer interface [polypeptide binding]; other site 216591029730 NAD binding pocket [chemical binding]; other site 216591029731 ATP binding pocket [chemical binding]; other site 216591029732 Mg binding site [ion binding]; other site 216591029733 active-site loop [active] 216591029734 HMMPfam hit to PF02540, NAD synthase, score 2.3e-75 216591029735 Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939 216591029736 Serine carboxypeptidase; Region: Peptidase_S10; cl08270 216591029737 HMMPfam hit to PF00450, Serine carboxypeptidase, score 4.1e-06 216591029738 Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377 216591029739 peptidase domain interface [polypeptide binding]; other site 216591029740 Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056 216591029741 active site 216591029742 catalytic triad [active] 216591029743 calcium binding site [ion binding]; other site 216591029744 HMMPfam hit to PF00082, Subtilase family, score 0.00013 216591029745 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591029746 HMMPfam hit to PF01810, LysE type translocator, score 3e-33 216591029747 4 probable transmembrane helices predicted for BCAM2479 by TMHMM2.0 at aa 7-29, 44-66, 73-92 and 147-169 216591029748 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591029749 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591029750 putative DNA binding site [nucleotide binding]; other site 216591029751 putative Zn2+ binding site [ion binding]; other site 216591029752 AsnC family; Region: AsnC_trans_reg; pfam01037 216591029753 Predicted helix-turn-helix motif with score 1243.000, SD 3.42 at aa 21-42, sequence LPIARLAESVGLSETPCARRLK 216591029754 HMMPfam hit to PF01037, AsnC family, score 1.1e-25 216591029755 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591029756 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591029757 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591029758 dimerization interface [polypeptide binding]; other site 216591029759 HMMPfam hit to PF03466, LysR substrate binding domain, score 4e-29 216591029760 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.7e-13 216591029761 Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592 216591029762 agmatinase; Region: agmatinase; TIGR01230 216591029763 oligomer interface [polypeptide binding]; other site 216591029764 putative active site [active] 216591029765 Mn binding site [ion binding]; other site 216591029766 HMMPfam hit to PF00491, Arginase family, score 3.2e-58 216591029767 PS00147 Arginase family signature 1. 216591029768 PS00148 Arginase family signature 2. 216591029769 PS01053 Arginase family signature 3. 216591029770 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591029771 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029772 putative substrate translocation pore; other site 216591029773 HMMPfam hit to PF00083, Sugar (and other) transporter score 6.7e-07 216591029774 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.3e-23 216591029775 12 probable transmembrane helices predicted for BCAM2483 by TMHMM2.0 at aa 21-43, 53-75, 84-106, 116-138, 150-172, 187-206, 235-257, 272-294, 301-323, 333-355, 362-384 and 394-416 216591029776 PS00217 Sugar transport proteins signature 2. 216591029777 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222 216591029778 CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312 216591029779 THF binding site; other site 216591029780 CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311 216591029781 substrate binding site [chemical binding]; other site 216591029782 THF binding site; other site 216591029783 zinc-binding site [ion binding]; other site 216591029784 HMMPfam hit to PF01717, Cobalamin-independent synthase, Catalytic, score 4.1e-217 216591029785 HMMPfam hit to PF08267, Cobalamin-independent synthase, N-termina, score 8e-165 216591029786 DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421 216591029787 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591029788 The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441 216591029789 putative dimerization interface [polypeptide binding]; other site 216591029790 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.5e-17 216591029791 Predicted helix-turn-helix motif with score 1743.000, SD 5.12 at aa 17-38, sequence GSLTAAAHALHLTQSALSHTVR 216591029792 PS00044 Bacterial regulatory proteins, lysR family signature. 216591029793 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.2e-34 216591029794 Probable cobalt transporter subunit (CbtA); Region: CbtA; cl02266 216591029795 6 probable transmembrane helices predicted for BCAM2486 by TMHMM2.0 at aa 5-24, 63-85, 98-117, 132-154, 167-186 and 206-228 216591029796 Probable cobalt transporter subunit (CbtB); Region: CbtB; cl09723 216591029797 1 probable transmembrane helix predicted for BCAM2487 by TMHMM2.0 at aa 20-39 216591029798 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 216591029799 catalytic core [active] 216591029800 HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 2e-18 216591029801 PS00387 Inorganic pyrophosphatase signature. 216591029802 Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306 216591029803 Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306 216591029804 10 probable transmembrane helices predicted for BCAM2489 by TMHMM2.0 at aa 21-43, 53-75, 95-117, 137-159, 166-183, 198-220, 240-257, 267-284, 412-431 and 504-526 216591029805 HMMPfam hit to PF01384, Phosphate transporter family, score 3.1e-54 216591029806 Uncharacterized protein conserved in bacteria (DUF2086); Region: DUF2086; pfam09859 216591029807 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029808 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591029809 putative substrate translocation pore; other site 216591029810 14 probable transmembrane helices predicted for BCAM2491 by TMHMM2.0 at aa 13-35, 50-72, 81-103, 108-127, 140-162, 167-189, 202-219, 229-248, 260-282, 292-314, 335-354, 358-380, 401-423 and 438-460 216591029811 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.7e-52 216591029812 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029813 phosphonate degradation operons associated HDIG domain protein; Region: Phn-HD; TIGR03276 216591029814 putative phosphonoacetaldehyde dehydrogenase; Region: PhnAcAld_DH; TIGR03250 216591029815 Streptomyces putative phosphonoformaldehyde dehydrogenase PhpJ-like; Region: ALDH_PhpJ; cd07146 216591029816 NAD(P) binding site [chemical binding]; other site 216591029817 catalytic residues [active] 216591029818 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.9e-178 216591029819 PS00070 Aldehyde dehydrogenases cysteine active site. 216591029820 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591029821 phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335 216591029822 Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663 216591029823 HMMPfam hit to PF01663, Type I phosphodiesterase / nucleotide py, score 3.7e-13 216591029824 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 216591029825 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591029826 conserved gate region; other site 216591029827 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.00054 216591029828 6 probable transmembrane helices predicted for BCAM2495 by TMHMM2.0 at aa 35-57, 90-112, 125-147, 157-176, 221-243 and 258-280 216591029829 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591029830 2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050 216591029831 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591029832 dimer interface [polypeptide binding]; other site 216591029833 conserved gate region; other site 216591029834 putative PBP binding loops; other site 216591029835 ABC-ATPase subunit interface; other site 216591029836 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.6e-18 216591029837 6 probable transmembrane helices predicted for BCAM2496 by TMHMM2.0 at aa 21-43, 76-98, 110-131, 151-173, 213-235 and 255-277 216591029838 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591029839 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258 216591029840 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591029841 Walker A/P-loop; other site 216591029842 ATP binding site [chemical binding]; other site 216591029843 Q-loop/lid; other site 216591029844 ABC transporter signature motif; other site 216591029845 Walker B; other site 216591029846 D-loop; other site 216591029847 H-loop/switch region; other site 216591029848 TOBE domain; Region: TOBE_2; pfam08402 216591029849 HMMPfam hit to PF08402, TOBE domain, score 1.9e-10 216591029850 HMMPfam hit to PF00005, ABC transporter score 3.8e-57 216591029851 PS00211 ABC transporters family signature. 216591029852 PS00017 ATP/GTP-binding site motif A (P-loop). 216591029853 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 216591029854 Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416 216591029855 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 3.3e-07 216591029856 2-aminoethylphosphonate--pyruvate transaminase; Provisional; Region: PRK13479 216591029857 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591029858 catalytic residue [active] 216591029859 HMMPfam hit to PF00266, Aminotransferase class-V, score 2e-07 216591029860 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029861 D-galactonate transporter; Region: 2A0114; TIGR00893 216591029862 putative substrate translocation pore; other site 216591029863 11 probable transmembrane helices predicted for BCAM2500 by TMHMM2.0 at aa 27-49, 56-78, 98-120, 155-177, 182-201, 256-278, 293-315, 327-349, 355-377, 390-412 and 417-439 216591029864 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.8e-66 216591029865 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029866 shikimate 5-dehydrogenase; Reviewed; Region: PRK12549 216591029867 Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501 216591029868 NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065 216591029869 shikimate binding site; other site 216591029870 NAD(P) binding site [chemical binding]; other site 216591029871 HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase, score 1.5e-05 216591029872 HMMPfam hit to PF08501, Shikimate dehydrogenase substrate bind, score 1.3e-25 216591029873 Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466 216591029874 Dehydroquinase class II; Region: DHquinase_II; pfam01220 216591029875 active site 216591029876 trimer interface [polypeptide binding]; other site 216591029877 dimer interface [polypeptide binding]; other site 216591029878 HMMPfam hit to PF01220, Dehydroquinase class II, score 1.2e-79 216591029879 PS01029 Dehydroquinase class II signature. 216591029880 Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082 216591029881 4-hydroxyphenylpyruvate dioxygenase; Region: 4HPPD; TIGR01263 216591029882 N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342 216591029883 dimer interface [polypeptide binding]; other site 216591029884 C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250 216591029885 active site 216591029886 Fe binding site [ion binding]; other site 216591029887 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 5.3e-41 216591029888 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/, score 9.8e-08 216591029889 SPRY-associated domain; Region: PRY; cl02686 216591029890 PAS fold; Region: PAS_4; pfam08448 216591029891 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459 216591029892 putative active site [active] 216591029893 heme pocket [chemical binding]; other site 216591029894 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591029895 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591029896 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591029897 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.6e-10 216591029898 PS00041 Bacterial regulatory proteins, araC family signature. 216591029899 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2e-07 216591029900 Predicted helix-turn-helix motif with score 1937.000, SD 5.78 at aa 175-196, sequence LNLKQLAQMAGMSVAQLERYFH 216591029901 HMMPfam hit to PF08448, PAS fold, score 9.2e-17 216591029902 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591029903 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 216591029904 dimerization interface [polypeptide binding]; other site 216591029905 ligand binding site [chemical binding]; other site 216591029906 HMMPfam hit to PF01094, Receptor family ligand binding region, score 6.7e-48 216591029907 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591029908 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029909 putative substrate translocation pore; other site 216591029910 HMMPfam hit to PF00083, Sugar (and other) transporter score 8e-07 216591029911 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.9e-21 216591029912 11 probable transmembrane helices predicted for BCAM2507 by TMHMM2.0 at aa 32-54, 67-89, 109-131, 160-182, 197-216, 251-273, 288-310, 317-339, 344-366, 379-401 and 406-425 216591029913 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029914 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029915 Predicted membrane protein [Function unknown]; Region: COG2259 216591029916 4 probable transmembrane helices predicted for BCAM2508 by TMHMM2.0 at aa 33-55, 70-92, 97-116 and 131-153 216591029917 HMMPfam hit to PF07681, DoxX, score 6.1e-23 216591029918 Fucose dissimilation pathway protein FucU [Carbohydrate transport and metabolism]; Region: FucU; COG4154 216591029919 HMMPfam hit to PF05025, RbsD / FucU transport protein family, score 6.1e-16 216591029920 SnoaL-like domain; Region: SnoaL_2; pfam12680 216591029921 galactarate dehydratase; Region: galactar-dH20; TIGR03248 216591029922 Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613 216591029923 D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295 216591029924 HMMPfam hit to PF04295, D-galactarate dehydratase / Altronate hydrol, score 3.5e-205 216591029925 HMMPfam hit to PF04292, D-galactarate dehydratase / Altronate hydrol, score 3.7e-31 216591029926 Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329 216591029927 5-dehydro-4-deoxyglucarate dehydratase, also called 5-keto-4-deoxy-glucarate dehydratase (KDGDH); Region: KDGDH; cd00951 216591029928 putative active site [active] 216591029929 catalytic residue [active] 216591029930 HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 1.1e-124 216591029931 NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012 216591029932 Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129 216591029933 dimer interface [polypeptide binding]; other site 216591029934 NADP binding site [chemical binding]; other site 216591029935 catalytic residues [active] 216591029936 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 7e-14 216591029937 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591029938 D-galactonate transporter; Region: 2A0114; TIGR00893 216591029939 putative substrate translocation pore; other site 216591029940 12 probable transmembrane helices predicted for BCAM2515 by TMHMM2.0 at aa 21-40, 55-77, 98-120, 124-146, 159-181, 186-208, 262-284, 299-321, 328-350, 360-382, 391-413 and 423-445 216591029941 HMMPfam hit to PF00083, Sugar (and other) transporter score 8.6e-05 216591029942 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.8e-57 216591029943 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029944 Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_2; cd06160 216591029945 Peptidase family M50; Region: Peptidase_M50; pfam02163 216591029946 active site 216591029947 putative substrate binding region [chemical binding]; other site 216591029948 6 probable transmembrane helices predicted for BCAM2516 by TMHMM2.0 at aa 28-50, 63-80, 90-112, 119-141, 161-183 and 212-234 216591029949 HMMPfam hit to PF02163, Peptidase family M50, score 4.7e-09 216591029950 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591029951 Protein of unknown function (DUF2167); Region: DUF2167; pfam09935 216591029952 1 probable transmembrane helix predicted for BCAM2517 by TMHMM2.0 at aa 266-288 216591029953 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591029954 non-specific DNA binding site [nucleotide binding]; other site 216591029955 salt bridge; other site 216591029956 sequence-specific DNA binding site [nucleotide binding]; other site 216591029957 HMMPfam hit to PF01381, Helix-turn-helix, score 2.8e-08 216591029958 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591029959 HMMPfam hit to PF01810, LysE type translocator, score 1.5e-36 216591029960 5 probable transmembrane helices predicted for BCAM2519 by TMHMM2.0 at aa 4-26, 38-60, 70-92, 112-134 and 149-171 216591029961 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591029962 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591029963 putative DNA binding site [nucleotide binding]; other site 216591029964 putative Zn2+ binding site [ion binding]; other site 216591029965 AsnC family; Region: AsnC_trans_reg; pfam01037 216591029966 HMMPfam hit to PF01037, AsnC family, score 6.5e-31 216591029967 dihydroorotase; Validated; Region: PRK09060 216591029968 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 216591029969 Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318 216591029970 active site 216591029971 HMMPfam hit to PF01979, Amidohydrolase family, score 1.3e-13 216591029972 HMMPfam hit to PF07969, Amidohydrolase family, score 0.00045 216591029973 PS00483 Dihydroorotase signature 2. 216591029974 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663 216591029975 Gamma carbonic anhydrases (CA): Carbonic anhydrases are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism, involving the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed...; Region: LbH_gamma_CA; cd00710 216591029976 trimer interface [polypeptide binding]; other site 216591029977 active site 216591029978 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 3.5 216591029979 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 5.1 216591029980 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1.3 216591029981 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.03 216591029982 6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242 216591029983 putative GTP cyclohydrolase; Provisional; Region: PRK13674 216591029984 HMMPfam hit to PF02649, Uncharacterized ACR, COG1469, score 1.1e-08 216591029985 Putative GTPases (G3E family) [General function prediction only]; Region: COG0523 216591029986 CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492 216591029987 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833 216591029988 HMMPfam hit to PF07683, Cobalamin synthesis protein cobW C-terminal, score 3.4e-39 216591029989 HMMPfam hit to PF02492, CobW/HypB/UreG, nucleotide-binding domain, score 1.1e-88 216591029990 PS00017 ATP/GTP-binding site motif A (P-loop). 216591029991 sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022 216591029992 Dibenzothiophene (DBT) desulfurization enzyme C; Region: DszC; cd01163 216591029993 Flavin binding site [chemical binding]; other site 216591029994 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 0.0014 216591029995 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 6.7e-25 216591029996 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591029997 dimer interface [polypeptide binding]; other site 216591029998 conserved gate region; other site 216591029999 ABC-ATPase subunit interface; other site 216591030000 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 9.3e-22 216591030001 5 probable transmembrane helices predicted for BCAM2528 by TMHMM2.0 at aa 20-42, 54-76, 86-108, 147-169 and 184-206 216591030002 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591030003 ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258 216591030004 DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153 216591030005 Walker A/P-loop; other site 216591030006 ATP binding site [chemical binding]; other site 216591030007 Q-loop/lid; other site 216591030008 ABC transporter signature motif; other site 216591030009 Walker B; other site 216591030010 D-loop; other site 216591030011 H-loop/switch region; other site 216591030012 This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930 216591030013 HMMPfam hit to PF00005, ABC transporter score 8e-72 216591030014 PS00211 ABC transporters family signature. 216591030015 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030016 FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860 216591030017 nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095 216591030018 active site 216591030019 non-prolyl cis peptide bond; other site 216591030020 NLPA lipoprotein; Region: Lipoprotein_9; pfam03180 216591030021 HMMPfam hit to PF03180, NLPA lipoprotein, score 1.1e-99 216591030022 2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390 216591030023 11 probable transmembrane helices predicted for BCAM2532 by TMHMM2.0 at aa 36-58, 62-84, 91-113, 128-145, 158-177, 187-209, 222-244, 304-323, 335-357, 367-389 and 433-452 216591030024 HMMPfam hit to PF03390, Bacterial sodium:citrate symporter, score 1.3e-186 216591030025 Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms]; Region: COG4191 216591030026 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591030027 dimer interface [polypeptide binding]; other site 216591030028 phosphorylation site [posttranslational modification] 216591030029 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591030030 ATP binding site [chemical binding]; other site 216591030031 Mg2+ binding site [ion binding]; other site 216591030032 G-X-G motif; other site 216591030033 2 probable transmembrane helices predicted for BCAM2533 by TMHMM2.0 at aa 15-32 and 309-328 216591030034 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.9e-05 216591030035 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.4e-33 216591030036 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 216591030037 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591030038 active site 216591030039 phosphorylation site [posttranslational modification] 216591030040 intermolecular recognition site; other site 216591030041 dimerization interface [polypeptide binding]; other site 216591030042 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591030043 Walker A motif; other site 216591030044 ATP binding site [chemical binding]; other site 216591030045 Walker B motif; other site 216591030046 arginine finger; other site 216591030047 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591030048 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.6e-31 216591030049 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 5.4e-135 216591030050 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591030051 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591030052 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591030053 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 3e-10 216591030054 Predicted helix-turn-helix motif with score 1377.000, SD 3.88 at aa 416-437, sequence GNVADASEALGMPKKTLYHKLR 216591030055 Protein of unknown function (DUF3579); Region: DUF3579; pfam12112 216591030056 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591030057 Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303 216591030058 catalytic site [active] 216591030059 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 3.1e-09 216591030060 PS00120 Lipases, serine active site. 216591030061 Bacterial Transmembrane Pair family; Region: BTP; pfam05232 216591030062 Bacterial Transmembrane Pair family; Region: BTP; pfam05232 216591030063 HMMPfam hit to PF05232, Bacterial Transmembrane Pair family, score 4.1e-20 216591030064 4 probable transmembrane helices predicted for BCAM2537 by TMHMM2.0 at aa 7-29, 34-56, 77-99 and 106-128 216591030065 HMMPfam hit to PF05232, Bacterial Transmembrane Pair family, score 2.1e-12 216591030066 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591030067 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591030068 LysR substrate binding domain; Region: LysR_substrate; pfam03466 216591030069 dimerization interface [polypeptide binding]; other site 216591030070 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.5e-18 216591030071 Predicted helix-turn-helix motif with score 1629.000, SD 4.74 at aa 17-38, sequence GSFSAAARALGRTPSAVSMAIA 216591030072 PS00044 Bacterial regulatory proteins, lysR family signature. 216591030073 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.7e-29 216591030074 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591030075 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591030076 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591030077 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591030078 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 9.5e-07 216591030079 PS00041 Bacterial regulatory proteins, araC family signature. 216591030080 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 7.3e-06 216591030081 11 probable transmembrane helices predicted for BCAM2540 by TMHMM2.0 at aa 21-43, 58-80, 101-123, 138-160, 187-209, 214-233, 339-361, 381-403, 410-431, 446-468 and 481-503 216591030082 1 probable transmembrane helix predicted for BCAM2543 by TMHMM2.0 at aa 13-35 216591030083 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591030084 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591030085 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591030086 dimerization interface [polypeptide binding]; other site 216591030087 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.6e-34 216591030088 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.9e-19 216591030089 PS00044 Bacterial regulatory proteins, lysR family signature. 216591030090 Predicted helix-turn-helix motif with score 1143.000, SD 3.08 at aa 40-61, sequence GSIRGAADSINTAPSVITRQIR 216591030091 D-galactonate transporter; Region: 2A0114; TIGR00893 216591030092 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591030093 putative substrate translocation pore; other site 216591030094 12 probable transmembrane helices predicted for BCAM2545 by TMHMM2.0 at aa 25-42, 57-79, 99-114, 124-146, 153-175, 185-207, 250-272, 287-306, 319-336, 340-362, 369-391 and 406-425 216591030095 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.1e-52 216591030096 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030097 Uncharacterized conserved protein [Function unknown]; Region: COG5476 216591030098 Protein of unknown function (DUF1485); Region: DUF1485; pfam07364 216591030099 MlrC C-terminus; Region: MlrC_C; pfam07171 216591030100 HMMPfam hit to PF07364, Protein of unknown function (DUF1485), score 8.4e-15 216591030101 HMMPfam hit to PF07171, MlrC C-terminus, score 4.9e-85 216591030102 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591030103 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587 216591030104 active site 216591030105 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 7.3e-07 216591030106 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591030107 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591030108 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.7e-07 216591030109 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591030110 HMMPfam hit to PF02321, Outer membrane efflux protein, score 3.4e-52 216591030111 HMMPfam hit to PF02321, Outer membrane efflux protein, score 8.2e-47 216591030112 1 probable transmembrane helix predicted for BCAM2549 by TMHMM2.0 at aa 26-48 216591030113 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030114 AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873 216591030115 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 216591030116 12 probable transmembrane helices predicted for BCAM2550 by TMHMM2.0 at aa 12-34, 343-362, 369-391, 396-418, 439-461, 476-498, 550-572, 881-900, 907-929, 934-956, 977-999 and 1014-1036 216591030117 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 216591030118 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591030119 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591030120 PS00215 Mitochondrial energy transfer proteins signature. 216591030121 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.3e-52 216591030122 1 probable transmembrane helix predicted for BCAM2551 by TMHMM2.0 at aa 12-34 216591030123 Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312 216591030124 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 216591030125 substrate binding pocket [chemical binding]; other site 216591030126 HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 7.1e-77 216591030127 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591030128 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591030129 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472 216591030130 putative effector binding pocket; other site 216591030131 putative dimerization interface [polypeptide binding]; other site 216591030132 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.5e-16 216591030133 PS00044 Bacterial regulatory proteins, lysR family signature. 216591030134 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.7e-48 216591030135 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591030136 Purine nucleoside permease (NUP); Region: NUP; pfam06516 216591030137 HMMPfam hit to PF06516, Purine nucleoside permease (NUP), score 7.7e-203 216591030138 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030139 LysE type translocator; Region: LysE; cl00565 216591030140 HMMPfam hit to PF01810, LysE type translocator, score 4.1e-05 216591030141 5 probable transmembrane helices predicted for BCAM2557 by TMHMM2.0 at aa 4-26, 47-69, 111-133, 140-162 and 172-194 216591030142 selenophosphate synthetase; Provisional; Region: PRK00943 216591030143 Selenophosphate synthetase (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195 216591030144 dimerization interface [polypeptide binding]; other site 216591030145 putative ATP binding site [chemical binding]; other site 216591030146 HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 3.7e-21 216591030147 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030148 HMMPfam hit to PF00586, AIR synthase related protein, N-terminal dom, score 3.4e-07 216591030149 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030150 phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340 216591030151 9 probable transmembrane helices predicted for BCAM2559 by TMHMM2.0 at aa 4-23, 30-52, 57-76, 89-108, 113-132, 139-158, 173-192, 205-227 and 232-254 216591030152 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 7.6e-08 216591030153 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591030154 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591030155 DNA-binding site [nucleotide binding]; DNA binding site 216591030156 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591030157 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591030158 homodimer interface [polypeptide binding]; other site 216591030159 catalytic residue [active] 216591030160 HMMPfam hit to PF00155, Aminotransferase class I and II, score 2.8e-12 216591030161 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030162 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 8e-14 216591030163 4-aminobutyrate aminotransferase; Provisional; Region: PRK06777 216591030164 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591030165 inhibitor-cofactor binding pocket; inhibition site 216591030166 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591030167 catalytic residue [active] 216591030168 PS00636 Nt-dnaJ domain signature. 216591030169 HMMPfam hit to PF00202, Aminotransferase class-III, score 7.3e-149 216591030170 HMMPfam hit to PF00155, Aminotransferase class I and II, score 8.9e-05 216591030171 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591030172 succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241 216591030173 Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103 216591030174 tetramerization interface [polypeptide binding]; other site 216591030175 NAD(P) binding site [chemical binding]; other site 216591030176 catalytic residues [active] 216591030177 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 2e-234 216591030178 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591030179 PS00070 Aldehyde dehydrogenases cysteine active site. 216591030180 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591030181 PAS domain; Region: PAS_9; pfam13426 216591030182 putative active site [active] 216591030183 heme pocket [chemical binding]; other site 216591030184 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 216591030185 dimerization interface [polypeptide binding]; other site 216591030186 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 216591030187 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591030188 dimer interface [polypeptide binding]; other site 216591030189 putative CheW interface [polypeptide binding]; other site 216591030190 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 2.9e-93 216591030191 HMMPfam hit to PF00672, HAMP domain, score 1.1e-06 216591030192 2 probable transmembrane helices predicted for BCAM2563 by TMHMM2.0 at aa 206-228 and 232-254 216591030193 HMMPfam hit to PF08447, PAS fold, score 8.3e-19 216591030194 HMMPfam hit to PF00989, PAS fold, score 9.8e-05 216591030195 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591030196 PAS domain; Region: PAS_9; pfam13426 216591030197 putative active site [active] 216591030198 heme pocket [chemical binding]; other site 216591030199 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054 216591030200 dimerization interface [polypeptide binding]; other site 216591030201 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 216591030202 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591030203 dimer interface [polypeptide binding]; other site 216591030204 putative CheW interface [polypeptide binding]; other site 216591030205 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 4.8e-95 216591030206 HMMPfam hit to PF00672, HAMP domain, score 2.2e-07 216591030207 PS00217 Sugar transport proteins signature 2. 216591030208 2 probable transmembrane helices predicted for BCAM2564 by TMHMM2.0 at aa 169-186 and 190-212 216591030209 HMMPfam hit to PF08447, PAS fold, score 2.1e-13 216591030210 Methyltransferase domain; Region: Methyltransf_31; pfam13847 216591030211 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591030212 S-adenosylmethionine binding site [chemical binding]; other site 216591030213 HMMPfam hit to PF08241, Methyltransferase domain, score 7.2e-11 216591030214 HMMPfam hit to PF08242, Methyltransferase domain, score 9.8e-12 216591030215 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591030216 Coenzyme A binding pocket [chemical binding]; other site 216591030217 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.7e-11 216591030218 Uncharacterized conserved protein [Function unknown]; Region: COG1683 216591030219 HMMPfam hit to PF04463, Protein of unknown function (DUF523), score 5.7e-62 216591030220 beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050 216591030221 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 216591030222 dimer interface [polypeptide binding]; other site 216591030223 active site 216591030224 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 1.3e-60 216591030225 PS00099 Thiolases active site. 216591030226 PS00737 Thiolases signature 2. 216591030227 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 1.1e-99 216591030228 PS00098 Thiolases acyl-enzyme intermediate signature. 216591030229 beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Region: pcaR_pcaU; TIGR02431 216591030230 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 216591030231 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591030232 Predicted helix-turn-helix motif with score 1014.000, SD 2.64 at aa 67-88, sequence QTLTEVASATGLTRAGARRILL 216591030233 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 1.1e-45 216591030234 Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like subfamily; subgroup includes Pseudomonas aeruginosa AotO; Region: M14_PaAOTO_like; cd06250 216591030235 Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952 216591030236 active site 216591030237 Zn binding site [ion binding]; other site 216591030238 HMMPfam hit to PF04952, Succinylglutamate desuccinylase / Aspartoac, score 1.5e-07 216591030239 ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010 216591030240 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591030241 substrate binding pocket [chemical binding]; other site 216591030242 membrane-bound complex binding site; other site 216591030243 hinge residues; other site 216591030244 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.6e-72 216591030245 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591030246 putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791 216591030247 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591030248 LysR substrate binding domain; Region: LysR_substrate; pfam03466 216591030249 dimerization interface [polypeptide binding]; other site 216591030250 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.7e-20 216591030251 Predicted helix-turn-helix motif with score 1354.000, SD 3.80 at aa 18-39, sequence GSLRAAARALDLAQSGVTQQLQ 216591030252 PS00044 Bacterial regulatory proteins, lysR family signature. 216591030253 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.1e-22 216591030254 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591030255 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591030256 putative substrate translocation pore; other site 216591030257 HMMPfam hit to PF00083, Sugar (and other) transporter score 9e-08 216591030258 10 probable transmembrane helices predicted for BCAM2573 by TMHMM2.0 at aa 35-57, 72-94, 103-125, 203-222, 254-276, 289-311, 323-340, 345-364, 385-407 and 417-434 216591030259 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.6e-19 216591030260 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030261 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 216591030262 M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666 216591030263 metal binding site [ion binding]; metal-binding site 216591030264 putative dimer interface [polypeptide binding]; other site 216591030265 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 2.2e-64 216591030266 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 8.4e-10 216591030267 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591030268 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591030269 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591030270 putative effector binding pocket; other site 216591030271 dimerization interface [polypeptide binding]; other site 216591030272 HMMPfam hit to PF03466, LysR substrate binding domain, score 6e-45 216591030273 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 7.7e-13 216591030274 Predicted helix-turn-helix motif with score 1134.000, SD 3.05 at aa 11-32, sequence GSMTAGAVALGSTPSVLSRAIT 216591030275 Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141 216591030276 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 216591030277 potential catalytic triad [active] 216591030278 conserved cys residue [active] 216591030279 PS01095 Chitinases family 18 active site. 216591030280 HMMPfam hit to PF01965, DJ-1/PfpI family, score 2.2e-12 216591030281 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591030282 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 216591030283 Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141 216591030284 potential catalytic triad [active] 216591030285 conserved cys residue [active] 216591030286 1 probable transmembrane helix predicted for BCAM2577 by TMHMM2.0 at aa 12-34 216591030287 HMMPfam hit to PF01965, DJ-1/PfpI family, score 6e-18 216591030288 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 216591030289 classical (c) SDRs; Region: SDR_c; cd05233 216591030290 NAD(P) binding site [chemical binding]; other site 216591030291 active site 216591030292 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.5e-16 216591030293 Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618 216591030294 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 216591030295 active site 216591030296 HMMPfam hit to PF04909, Amidohydrolase, score 8.3e-47 216591030297 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591030298 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591030299 putative substrate translocation pore; other site 216591030300 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030301 12 probable transmembrane helices predicted for BCAM2580 by TMHMM2.0 at aa 19-36, 56-75, 88-107, 113-135, 148-170, 180-202, 248-270, 280-302, 314-332, 336-358, 370-392 and 402-424 216591030302 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.7e-41 216591030303 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030304 H+ Antiporter protein; Region: 2A0121; TIGR00900 216591030305 HMMPfam hit to PF05977, Bacterial protein of unknown function (DUF89, score 0.00071 216591030306 9 probable transmembrane helices predicted for BCAM2581 by TMHMM2.0 at aa 52-74, 87-109, 181-198, 229-248, 263-285, 292-311, 316-338, 350-372 and 382-399 216591030307 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030308 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.4e-16 216591030309 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030310 benzoate transport; Region: 2A0115; TIGR00895 216591030311 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591030312 putative substrate translocation pore; other site 216591030313 HMMPfam hit to PF00083, Sugar (and other) transporter score 3.7e-06 216591030314 12 probable transmembrane helices predicted for BCAM2582 by TMHMM2.0 at aa 35-57, 67-89, 98-116, 121-143, 156-178, 188-207, 238-260, 275-297, 309-331, 335-357, 369-391 and 395-417 216591030315 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.2e-47 216591030316 Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618 216591030317 Amidohydrolase; Region: Amidohydro_2; pfam04909 216591030318 HMMPfam hit to PF04909, Amidohydrolase, score 6.6e-47 216591030319 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591030320 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591030321 trimer interface [polypeptide binding]; other site 216591030322 eyelet of channel; other site 216591030323 HMMPfam hit to PF00267, Gram-negative porin, score 0.00084 216591030324 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591030325 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591030326 putative substrate translocation pore; other site 216591030327 12 probable transmembrane helices predicted for BCAM2585 by TMHMM2.0 at aa 59-81, 94-116, 123-145, 149-171, 184-206, 216-238, 284-306, 316-338, 351-373, 378-400, 405-427 and 437-459 216591030328 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.4e-46 216591030329 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030330 SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450 216591030331 Strictosidine synthase; Region: Str_synth; pfam03088 216591030332 HMMPfam hit to PF08450, SMP-30/Gluconolaconase/LRE-like region, score 1.6e-13 216591030333 Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111 216591030334 Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240 216591030335 NAD binding site [chemical binding]; other site 216591030336 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 4.9e-17 216591030337 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 1.8e-81 216591030338 PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 216591030339 PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 216591030340 hypothetical protein; Validated; Region: PRK06201 216591030341 Demethylmenaquinone methyltransferase [Coenzyme metabolism]; Region: MenG; COG0684 216591030342 HMMPfam hit to PF03737, Demethylmenaquinone methyltransferase, score 9.9e-38 216591030343 PS00216 Sugar transport proteins signature 1. 216591030344 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591030345 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 216591030346 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591030347 Predicted helix-turn-helix motif with score 1340.000, SD 3.75 at aa 34-55, sequence QSLATLSQASGMHKTTVYRLMN 216591030348 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591030349 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591030350 putative substrate translocation pore; other site 216591030351 HMMPfam hit to PF00083, Sugar (and other) transporter score 8.1e-08 216591030352 12 probable transmembrane helices predicted for BCAM2590 by TMHMM2.0 at aa 5-27, 37-59, 80-102, 112-134, 146-165, 180-199, 247-266, 271-293, 300-319, 329-351, 364-386 and 390-412 216591030353 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1e-23 216591030354 PS00190 Cytochrome c family heme-binding site signature. 216591030355 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030356 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030357 PS00216 Sugar transport proteins signature 1. 216591030358 Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124 216591030359 Cytochrome P450; Region: p450; cl12078 216591030360 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018 216591030361 Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185 216591030362 FMN-binding pocket [chemical binding]; other site 216591030363 flavin binding motif; other site 216591030364 phosphate binding motif [ion binding]; other site 216591030365 beta-alpha-beta structure motif; other site 216591030366 NAD binding pocket [chemical binding]; other site 216591030367 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591030368 catalytic loop [active] 216591030369 iron binding site [ion binding]; other site 216591030370 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 8e-21 216591030371 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591030372 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 9.5e-06 216591030373 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 1.1e-05 216591030374 HMMPfam hit to PF08021, Siderophore-interacting FAD-binding dom, score 0.00078 216591030375 HMMPfam hit to PF00067, Cytochrome P450, score 1.7e-07 216591030376 PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 216591030377 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591030378 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 216591030379 Predicted helix-turn-helix motif with score 1052.000, SD 2.77 at aa 12-33, sequence ATLTALAARLDENPAKVHRYLA 216591030380 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 8.1e-05 216591030381 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591030382 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591030383 HMMPfam hit to PF02178, AT hook motif, score 0.02 216591030384 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 4.1e-15 216591030385 Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288 216591030386 putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823 216591030387 NADP binding site [chemical binding]; other site 216591030388 dimer interface [polypeptide binding]; other site 216591030389 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 1.1e-11 216591030390 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030391 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 4.8e-13 216591030392 uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926 216591030393 Carboxymuconolactone decarboxylase family; Region: CMD; cl00460 216591030394 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 1.7e-08 216591030395 Beta-lactamase; Region: Beta-lactamase; pfam00144 216591030396 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 216591030397 HMMPfam hit to PF00144, Beta-lactamase, score 3.1e-42 216591030398 1 probable transmembrane helix predicted for BCAM2596 by TMHMM2.0 at aa 9-31 216591030399 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591030400 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591030401 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591030402 dimerization interface [polypeptide binding]; other site 216591030403 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.2e-13 216591030404 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591030405 Predicted helix-turn-helix motif with score 1446.000, SD 4.11 at aa 21-42, sequence GSITKAAAHLGKDRSTVSELLE 216591030406 HMMPfam hit to PF03466, LysR substrate binding domain, score 2e-10 216591030407 short chain dehydrogenase; Provisional; Region: PRK06180 216591030408 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374 216591030409 NADP binding site [chemical binding]; other site 216591030410 active site 216591030411 steroid binding site; other site 216591030412 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00023 216591030413 HMMPfam hit to PF00106, short chain dehydrogenase, score 4.5e-24 216591030414 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591030415 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591030416 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 5.1e-13 216591030417 Predicted helix-turn-helix motif with score 1181.000, SD 3.21 at aa 38-59, sequence ATTARIAKLAGVAEGTVFTYFE 216591030418 glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722 216591030419 Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479 216591030420 Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781 216591030421 HMMPfam hit to PF00479, Glucose-6-phosphate dehydrogenase, NAD bindi, score 4.6e-82 216591030422 PS00069 Glucose-6-phosphate dehydrogenase active site. 216591030423 HMMPfam hit to PF02781, Glucose-6-phosphate dehydrogenase, C-termina, score 1.5e-149 216591030424 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591030425 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591030426 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591030427 dimerization interface [polypeptide binding]; other site 216591030428 HMMPfam hit to PF03466, LysR substrate binding domain, score 7.4e-43 216591030429 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 7.8e-18 216591030430 Predicted helix-turn-helix motif with score 1394.000, SD 3.93 at aa 18-39, sequence GSITAAAQQLDLTVSATSRTLA 216591030431 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591030432 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591030433 putative substrate translocation pore; other site 216591030434 12 probable transmembrane helices predicted for BCAM2602 by TMHMM2.0 at aa 7-29, 39-61, 68-90, 94-116, 128-150, 160-182, 202-224, 237-259, 272-289, 294-316, 336-358 and 363-382 216591030435 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.6e-50 216591030436 luciferase-type oxidoreductase, BA3436 family; Region: lucif_BA3436; TIGR03571 216591030437 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892 216591030438 N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097 216591030439 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 9.9e-05 216591030440 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591030441 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591030442 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 216591030443 active site 216591030444 catalytic tetrad [active] 216591030445 HMMPfam hit to PF00248, Aldo/keto reductase family, score 1.3e-95 216591030446 PS00798 Aldo/keto reductase family signature 1. 216591030447 PS00062 Aldo/keto reductase family signature 2. 216591030448 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591030449 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591030450 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591030451 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591030452 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030453 HMMPfam hit to PF01548, Transposase, score 2.9e-12 216591030454 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 216591030455 Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933 216591030456 FMN binding site [chemical binding]; other site 216591030457 active site 216591030458 substrate binding site [chemical binding]; other site 216591030459 catalytic residue [active] 216591030460 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 1.1e-88 216591030461 Putative cyclase; Region: Cyclase; pfam04199 216591030462 HMMPfam hit to PF04199, Putative cyclase, score 0.002 216591030463 Protein of unknown function (DUF3455); Region: DUF3455; pfam11937 216591030464 Methyltransferase domain; Region: Methyltransf_24; pfam13578 216591030465 HMMPfam hit to PF01596, O-methyltransferase, score 3e-06 216591030466 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591030467 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591030468 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 6.5e-15 216591030469 Predicted helix-turn-helix motif with score 1825.000, SD 5.40 at aa 43-64, sequence FTMARVAERAGVSVGSLYQYFP 216591030470 Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism]; Region: COG2252 216591030471 HMMPfam hit to PF00860, Permease family, score 3.4e-78 216591030472 12 probable transmembrane helices predicted for BCAM2612 by TMHMM2.0 at aa 42-64, 69-91, 96-115, 120-142, 149-171, 186-208, 215-237, 264-283, 348-370, 374-391, 404-426 and 441-460 216591030473 HMMPfam hit to PF00916, Sulfate transporter family, score 0.00045 216591030474 PS00211 ABC transporters family signature. 216591030475 Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863 216591030476 4 probable transmembrane helices predicted for BCAM2614 by TMHMM2.0 at aa 11-33, 46-68, 72-94 and 107-129 216591030477 PS00213 Lipocalin signature. 216591030478 Domain of unknown function (DUF3817); Region: DUF3817; pfam12823 216591030479 3 probable transmembrane helices predicted for BCAM2615 by TMHMM2.0 at aa 15-33, 40-62 and 77-96 216591030480 transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393 216591030481 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 216591030482 conserved cys residue [active] 216591030483 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591030484 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591030485 HMMPfam hit to PF01965, DJ-1/PfpI family, score 1.3e-19 216591030486 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 3.2e-09 216591030487 Predicted helix-turn-helix motif with score 1467.000, SD 4.18 at aa 224-245, sequence LTLDAIARKASTSVRTLTRRFQ 216591030488 PS00041 Bacterial regulatory proteins, araC family signature. 216591030489 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.2e-07 216591030490 Predicted helix-turn-helix motif with score 1467.000, SD 4.18 at aa 289-310, sequence AFRERFARIVGTSPQRYRQAFR 216591030491 putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791 216591030492 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591030493 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591030494 dimerization interface [polypeptide binding]; other site 216591030495 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6e-16 216591030496 Predicted helix-turn-helix motif with score 1778.000, SD 5.24 at aa 23-44, sequence KSLRAAARELGVTQPAITHTIR 216591030497 PS00044 Bacterial regulatory proteins, lysR family signature. 216591030498 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.3e-30 216591030499 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591030500 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591030501 substrate binding pocket [chemical binding]; other site 216591030502 membrane-bound complex binding site; other site 216591030503 hinge residues; other site 216591030504 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 8.1e-91 216591030505 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591030506 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030507 Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like subfamily; subgroup includes Pseudomonas aeruginosa AotO; Region: M14_PaAOTO_like; cd06250 216591030508 Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952 216591030509 active site 216591030510 Zn binding site [ion binding]; other site 216591030511 HMMPfam hit to PF04952, Succinylglutamate desuccinylase / Aspartoac, score 1.4e-07 216591030512 ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464 216591030513 NLPA lipoprotein; Region: Lipoprotein_9; pfam03180 216591030514 HMMPfam hit to PF03180, NLPA lipoprotein, score 2.1e-123 216591030515 CDS contains a nonsense mutation (opal) after codon 62. Similar to Burkholderia cenocepacia HI2424 porin, gram-negative type precursor UniProt:A0B3D4 (EMBL:CP000459 (385 aa) fasta scores: E()=5.1e-142, 95.844% id in 385 aa 216591030516 HMMPfam hit to PF00267, Gram-negative porin, score 2.6e-05 216591030517 Protein of unknown function (DUF2866); Region: DUF2866; pfam11065 216591030518 2 probable transmembrane helices predicted for BCAM2624 by TMHMM2.0 at aa 42-61 and 65-82 216591030519 TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786 216591030520 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591030521 N-terminal plug; other site 216591030522 ligand-binding site [chemical binding]; other site 216591030523 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 8.5e-28 216591030524 HMMPfam hit to PF00593, TonB dependent receptor, score 9.1e-33 216591030525 Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720 216591030526 Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171 216591030527 Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171 216591030528 HMMPfam hit to PF05171, Haemin-degrading family, score 1e-118 216591030529 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 216591030530 Periplasmic binding protein; Region: Peripla_BP_2; pfam01497 216591030531 intersubunit interface [polypeptide binding]; other site 216591030532 1 probable transmembrane helix predicted for BCAM2628 by TMHMM2.0 at aa 13-35 216591030533 HMMPfam hit to PF01497, Periplasmic binding protein, score 1.1e-40 216591030534 ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism]; Region: FepD; COG0609 216591030535 ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism]; Region: FepD; COG0609 216591030536 putative PBP binding regions; other site 216591030537 ABC-ATPase subunit interface; other site 216591030538 8 probable transmembrane helices predicted for BCAM2629 by TMHMM2.0 at aa 31-53, 84-106, 144-166, 173-195, 215-237, 269-291, 306-328 and 335-354 216591030539 HMMPfam hit to PF01032, FecCD transport family, score 5.8e-95 216591030540 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030541 hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13547 216591030542 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 216591030543 Walker A/P-loop; other site 216591030544 ATP binding site [chemical binding]; other site 216591030545 Q-loop/lid; other site 216591030546 ABC transporter signature motif; other site 216591030547 Walker B; other site 216591030548 D-loop; other site 216591030549 H-loop/switch region; other site 216591030550 HMMPfam hit to PF00005, ABC transporter score 6.7e-39 216591030551 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030552 PS00211 ABC transporters family signature. 216591030553 Predicted membrane protein [Function unknown]; Region: COG2860 216591030554 UPF0126 domain; Region: UPF0126; pfam03458 216591030555 UPF0126 domain; Region: UPF0126; pfam03458 216591030556 7 probable transmembrane helices predicted for BCAM2631 by TMHMM2.0 at aa 4-21, 28-45, 55-77, 86-108, 112-134, 146-165 and 169-191 216591030557 HMMPfam hit to PF03458, UPF0126 domain, score 2.1e-25 216591030558 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030559 HMMPfam hit to PF03458, UPF0126 domain, score 9.3e-28 216591030560 Transglycosylase; Region: Transgly; pfam00912 216591030561 penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074 216591030562 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 216591030563 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 3.5e-32 216591030564 HMMPfam hit to PF00912, Transglycosylase, score 1.3e-82 216591030565 1 probable transmembrane helix predicted for BCAM2632 by TMHMM2.0 at aa 28-47 216591030566 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030567 Aminoglycoside/hydroxyurea antibiotic resistance kinase; Region: APH_6_hur; cl17810 216591030568 HMMPfam hit to PF04655, Aminoglycoside/hydroxyurea antibiotic resis, score 6.6e-83 216591030569 Adenylate kinase and related kinases [Nucleotide transport and metabolism]; Region: Adk; COG0563 216591030570 Chloramphenicol (Cm) phosphotransferase (CPT). Cm-inactivating enzyme; modifies the primary (C-3) hydroxyl of the antibiotic. Related structurally to shikimate kinase II; Region: CPT; cl17391 216591030571 P-loop motif; other site 216591030572 ATP binding site [chemical binding]; other site 216591030573 Chloramphenicol (Cm) binding site [chemical binding]; other site 216591030574 catalytic residue [active] 216591030575 HMMPfam hit to PF07931, Chloramphenicol phosphotransferase-like prot, score 3.1e-21 216591030576 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030577 putative transposase OrfB; Reviewed; Region: PHA02517 216591030578 HTH-like domain; Region: HTH_21; pfam13276 216591030579 Integrase core domain; Region: rve; pfam00665 216591030580 Integrase core domain; Region: rve_2; pfam13333 216591030581 HMMPfam hit to PF00665, Integrase core domain, score 5.1e-42 216591030582 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591030583 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591030584 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591030585 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591030586 Predicted helix-turn-helix motif with score 1703.000, SD 4.99 at aa 20-41, sequence EAIRAVARTHGLSHSTVSQWYA 216591030587 hypothetical protein; Provisional; Region: PRK11171 216591030588 Cupin domain; Region: Cupin_2; pfam07883 216591030589 Cupin domain; Region: Cupin_2; pfam07883 216591030590 HMMPfam hit to PF07883, Cupin domain, score 1.3e-06 216591030591 HMMPfam hit to PF05899, Protein of unknown function (DUF861), score 1.3e-22 216591030592 HMMPfam hit to PF07883, Cupin domain, score 2.9e-15 216591030593 HMMPfam hit to PF05433, Rickettsia 17 kDa surface antigen, score 0.00077 216591030594 PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 216591030595 HMMPfam hit to PF05433, Rickettsia 17 kDa surface antigen, score 1.8e-06 216591030596 2 probable transmembrane helices predicted for BCAM2639 by TMHMM2.0 at aa 5-27 and 42-64 216591030597 Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020 216591030598 HMMPfam hit to PF04140, Isoprenylcysteine carboxyl methyltransferase, score 4.2e-10 216591030599 6 probable transmembrane helices predicted for BCAM2640 by TMHMM2.0 at aa 7-29, 39-58, 71-90, 105-124, 131-150 and 165-187 216591030600 2 probable transmembrane helices predicted for BCAM2640A by TMHMM2.0 at aa 23-45 and 50-72 216591030601 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030602 HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277 216591030603 HIT family signature motif; other site 216591030604 catalytic residue [active] 216591030605 HMMPfam hit to PF01230, HIT domain, score 5.2e-36 216591030606 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 216591030607 Beta-lactamase; Region: Beta-lactamase; pfam00144 216591030608 1 probable transmembrane helix predicted for BCAM2643 by TMHMM2.0 at aa 12-34 216591030609 HMMPfam hit to PF00144, Beta-lactamase, score 4.6e-31 216591030610 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591030611 GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047 216591030612 putative C-terminal domain interface [polypeptide binding]; other site 216591030613 putative GSH binding site (G-site) [chemical binding]; other site 216591030614 putative dimer interface [polypeptide binding]; other site 216591030615 C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180 216591030616 putative N-terminal domain interface [polypeptide binding]; other site 216591030617 putative dimer interface [polypeptide binding]; other site 216591030618 putative substrate binding pocket (H-site) [chemical binding]; other site 216591030619 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 4.8e-09 216591030620 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591030621 Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090 216591030622 NAD(P) binding site [chemical binding]; other site 216591030623 active site 216591030624 HMMPfam hit to PF08338, Domain of unknown function (DUF1731), score 5.7e-22 216591030625 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 0.0008 216591030626 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 1.8e-08 216591030627 HMMPfam hit to PF07993, Male sterility protein, score 0.00076 216591030628 4 probable transmembrane helices predicted for BCAM2645 by TMHMM2.0 at aa 53-72, 76-98, 111-133 and 148-165 216591030629 Protein of unknown function, DUF393; Region: DUF393; pfam04134 216591030630 4 probable transmembrane helices predicted for BCAM2646 by TMHMM2.0 at aa 148-170, 200-222, 234-253 and 257-279 216591030631 Predicted integral membrane protein (DUF2269); Region: DUF2269; pfam10027 216591030632 4 probable transmembrane helices predicted for BCAM2647 by TMHMM2.0 at aa 10-32, 53-75, 80-102 and 136-153 216591030633 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030634 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs; Region: NDUFA9_like_SDR_a; cd05271 216591030635 NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370 216591030636 putative NAD(P) binding site [chemical binding]; other site 216591030637 active site 216591030638 DoxX-like family; Region: DoxX_3; pfam13781 216591030639 4 probable transmembrane helices predicted for BCAM2648 by TMHMM2.0 at aa 251-273, 326-348, 363-385 and 392-414 216591030640 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 0.0031 216591030641 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 1.2e-06 216591030642 HMMPfam hit to PF07993, Male sterility protein, score 0.0012 216591030643 Predicted transcriptional regulators [Transcription]; Region: COG1510 216591030644 MarR family; Region: MarR_2; pfam12802 216591030645 trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656 216591030646 NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242 216591030647 Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241 216591030648 Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055 216591030649 HMMPfam hit to PF07055, Short-chain alcohol dehydrogenase, score 6.3e-297 216591030650 short chain dehydrogenase; Validated; Region: PRK08264 216591030651 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591030652 NAD(P) binding site [chemical binding]; other site 216591030653 active site 216591030654 HMMPfam hit to PF00106, short chain dehydrogenase, score 4.6e-15 216591030655 PS00061 Short-chain dehydrogenases/reductases family signature. 216591030656 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591030657 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591030658 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.2e-16 216591030659 Predicted helix-turn-helix motif with score 1236.000, SD 3.40 at aa 31-52, sequence VGLTELMKEAGFTQGGFYNHFK 216591030660 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 216591030661 1 probable transmembrane helix predicted for BCAM2653 by TMHMM2.0 at aa 7-25 216591030662 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 216591030663 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4e-14 216591030664 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030665 PS00101 Hexapeptide-repeat containing-transferases signature. 216591030666 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591030667 dimerization interface [polypeptide binding]; other site 216591030668 putative DNA binding site [nucleotide binding]; other site 216591030669 putative Zn2+ binding site [ion binding]; other site 216591030670 HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family, score 2.2e-06 216591030671 Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_3; cd08896 216591030672 putative hydrophobic ligand binding site [chemical binding]; other site 216591030673 HMMPfam hit to PF08327, Activator of Hsp90 ATPase homolog 1-like pro, score 2.8e-30 216591030674 Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_2; cd08895 216591030675 putative hydrophobic ligand binding site [chemical binding]; other site 216591030676 HMMPfam hit to PF08327, Activator of Hsp90 ATPase homolog 1-like pro, score 2.3e-12 216591030677 Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618 216591030678 Amidohydrolase; Region: Amidohydro_2; pfam04909 216591030679 HMMPfam hit to PF04909, Amidohydrolase, score 9.2e-46 216591030680 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591030681 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591030682 putative substrate translocation pore; other site 216591030683 12 probable transmembrane helices predicted for BCAM2659 by TMHMM2.0 at aa 30-52, 67-89, 96-115, 125-147, 154-176, 191-210, 252-274, 289-308, 315-337, 341-363, 375-397 and 407-429 216591030684 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.6e-48 216591030685 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591030686 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591030687 HMMPfam hit to PF02515, CoA-transferase family III, score 1.1e-47 216591030688 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938 216591030689 active site 216591030690 catalytic residues [active] 216591030691 metal binding site [ion binding]; metal-binding site 216591030692 HMMPfam hit to PF00682, HMGL-like, score 1.4e-39 216591030693 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 216591030694 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591030695 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591030696 Predicted helix-turn-helix motif with score 1600.000, SD 4.64 at aa 44-65, sequence LSLAELSRRTGLYKSTILRLLA 216591030697 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 4.2e-12 216591030698 DsbA family, 2-hydroxychromene-2-carboxylate (HCCA) isomerase subfamily; HCCA isomerase is a glutathione (GSH) dependent enzyme involved in the naphthalene catabolic pathway. It converts HCCA, a hemiketal formed spontaneously after ring cleavage of 1; Region: DsbA_HCCA_Iso; cd03022 216591030699 DSBA-like thioredoxin domain; Region: DSBA; pfam01323 216591030700 putative catalytic residue [active] 216591030701 HMMPfam hit to PF01323, DSBA-like thioredoxin domain, score 1.2e-15 216591030702 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591030703 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591030704 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591030705 putative effector binding pocket; other site 216591030706 dimerization interface [polypeptide binding]; other site 216591030707 HMMPfam hit to PF03466, LysR substrate binding domain, score 1e-33 216591030708 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.4e-21 216591030709 PS00044 Bacterial regulatory proteins, lysR family signature. 216591030710 Predicted helix-turn-helix motif with score 1792.000, SD 5.29 at aa 21-42, sequence GSLSAAAVQLHTTQPTISRRLQ 216591030711 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591030712 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591030713 10 probable transmembrane helices predicted for BCAM2665 by TMHMM2.0 at aa 32-54, 69-91, 104-126, 156-178, 237-259, 269-291, 303-320, 330-352, 365-387 and 391-408 216591030714 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.8e-32 216591030715 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 216591030716 Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671 216591030717 active site 216591030718 4 probable transmembrane helices predicted for BCAM2666 by TMHMM2.0 at aa 37-59, 72-94, 131-153 and 166-188 216591030719 HMMPfam hit to PF01569, PAP2 superfamily, score 4e-10 216591030720 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591030721 Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570 216591030722 C-terminal domain interface [polypeptide binding]; other site 216591030723 GSH binding site (G-site) [chemical binding]; other site 216591030724 dimer interface [polypeptide binding]; other site 216591030725 C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776 216591030726 dimer interface [polypeptide binding]; other site 216591030727 N-terminal domain interface [polypeptide binding]; other site 216591030728 substrate binding pocket (H-site) [chemical binding]; other site 216591030729 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 4.2e-05 216591030730 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 9.2e-08 216591030731 Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446 216591030732 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 216591030733 active site residue [active] 216591030734 HMMPfam hit to PF00581, Rhodanese-like domain, score 9.3e-14 216591030735 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 3e-28 216591030736 chromosome replication initiation inhibitor protein; Provisional; Region: PRK13348 216591030737 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591030738 The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428 216591030739 putative dimerization interface [polypeptide binding]; other site 216591030740 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 1e-16 216591030741 Predicted helix-turn-helix motif with score 1349.000, SD 3.78 at aa 20-41, sequence GSFEQAAVRLHVTASAVTQRVR 216591030742 PS00044 Bacterial regulatory proteins, lysR family signature. 216591030743 Protein of unknown function (DUF1059); Region: DUF1059; cl02284 216591030744 Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008 216591030745 Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502 216591030746 tetramer interface [polypeptide binding]; other site 216591030747 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591030748 catalytic residue [active] 216591030749 HMMPfam hit to PF01212, Beta-eliminating lyase, score 3.2e-138 216591030750 Glycine-zipper containing OmpA-like membrane domain; Region: Gly-zipper_OmpA; pfam13436 216591030751 2 probable transmembrane helices predicted for BCAM2672 by TMHMM2.0 at aa 13-35 and 94-116 216591030752 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030753 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030754 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 216591030755 Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654 216591030756 HMMPfam hit to PF01654, Bacterial Cytochrome Ubiquinol Oxidase, score 5.7e-205 216591030757 9 probable transmembrane helices predicted for BCAM2674 by TMHMM2.0 at aa 15-37, 57-79, 99-121, 128-150, 187-209, 222-239, 323-345, 358-380 and 408-430 216591030758 Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322 216591030759 cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219 216591030760 HMMPfam hit to PF02322, Cytochrome oxidase subunit II, score 2e-135 216591030761 8 probable transmembrane helices predicted for BCAM2675 by TMHMM2.0 at aa 13-35, 72-94, 114-136, 156-178, 191-210, 225-244, 257-279 and 299-321 216591030762 PS00079 Multicopper oxidases signature 1. 216591030763 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030764 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030765 1 probable transmembrane helix predicted for BCAM2676 by TMHMM2.0 at aa 7-29 216591030766 1 probable transmembrane helix predicted for BCAM2677 by TMHMM2.0 at aa 20-42 216591030767 Sulfatase; Region: Sulfatase; cl17466 216591030768 Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119 216591030769 Sulfatase; Region: Sulfatase; cl17466 216591030770 HMMPfam hit to PF00884, Sulfatase, score 0.0027 216591030771 HMMPfam hit to PF01663, Type I phosphodiesterase / nucleotide py, score 4.1e-15 216591030772 Domain of Unknown Function (DUF748); Region: DUF748; pfam05359 216591030773 Domain of Unknown Function (DUF748); Region: DUF748; pfam05359 216591030774 Domain of Unknown Function (DUF748); Region: DUF748; pfam05359 216591030775 Domain of Unknown Function (DUF748); Region: DUF748; pfam05359 216591030776 HMMPfam hit to PF05359, Domain of Unknown Function (DUF748), score 8.9e-45 216591030777 HMMPfam hit to PF05359, Domain of Unknown Function (DUF748), score 3.3e-24 216591030778 HMMPfam hit to PF05359, Domain of Unknown Function (DUF748), score 2.1e-07 216591030779 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030780 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030781 HMMPfam hit to PF05359, Domain of Unknown Function (DUF748), score 2.9e-20 216591030782 1 probable transmembrane helix predicted for BCAM2680 by TMHMM2.0 at aa 29-51 216591030783 Uncharacterized conserved protein [Function unknown]; Region: COG5361 216591030784 Protein of unknown function (DUF1254); Region: DUF1254; pfam06863 216591030785 Protein of unknown function (DUF1214); Region: DUF1214; cl08447 216591030786 HMMPfam hit to PF06742, Protein of unknown function (DUF1214), score 1.5e-40 216591030787 HMMPfam hit to PF06863, Protein of unknown function (DUF1254), score 9.4e-28 216591030788 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030789 HicB family; Region: HicB; pfam05534 216591030790 HMMPfam hit to PF05534, HicB family, score 4.4e-16 216591030791 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207 216591030792 metal-binding site [ion binding] 216591030793 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 216591030794 metal-binding site [ion binding] 216591030795 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 216591030796 metal-binding site [ion binding] 216591030797 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 216591030798 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 216591030799 metal-binding site [ion binding] 216591030800 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 216591030801 Soluble P-type ATPase [General function prediction only]; Region: COG4087 216591030802 HMMPfam hit to PF00403, Heavy-metal-associated domain, score 5.9e-15 216591030803 PS01047 Heavy-metal-associated domain. 216591030804 HMMPfam hit to PF00403, Heavy-metal-associated domain, score 5.5e-19 216591030805 PS01047 Heavy-metal-associated domain. 216591030806 HMMPfam hit to PF00403, Heavy-metal-associated domain, score 2.1e-19 216591030807 PS01047 Heavy-metal-associated domain. 216591030808 HMMPfam hit to PF00403, Heavy-metal-associated domain, score 1.3e-15 216591030809 PS01047 Heavy-metal-associated domain. 216591030810 8 probable transmembrane helices predicted for BCAM2683 by TMHMM2.0 at aa 375-394, 404-426, 439-456, 466-483, 621-643, 648-670, 970-989 and 993-1012 216591030811 HMMPfam hit to PF00122, E1-E2 ATPase, score 7e-97 216591030812 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030813 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 9.9e-30 216591030814 PS00154 E1-E2 ATPases phosphorylation site. 216591030815 PS01229 Hypothetical cof family signature 2. 216591030816 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591030817 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 6.4e-14 216591030818 PS00036 bZIP transcription factors basic domain signature. 216591030819 1 probable transmembrane helix predicted for BCAM2686 by TMHMM2.0 at aa 294-311 216591030820 MgtC family; Region: MgtC; pfam02308 216591030821 HMMPfam hit to PF02308, MgtC family, score 4.5e-51 216591030822 3 probable transmembrane helices predicted for BCAM2687 by TMHMM2.0 at aa 39-61, 71-90 and 103-134 216591030823 dimerization interface [polypeptide binding]; other site 216591030824 AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183 216591030825 putative active cleft [active] 216591030826 HMMPfam hit to PF07221, N-acylglucosamine 2-epimerase (GlcNAc, score 1.8e-67 216591030827 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030828 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591030829 methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048 216591030830 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181 216591030831 dimer interface [polypeptide binding]; other site 216591030832 ligand binding site [chemical binding]; other site 216591030833 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591030834 dimer interface [polypeptide binding]; other site 216591030835 putative CheW interface [polypeptide binding]; other site 216591030836 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 3.3e-92 216591030837 HMMPfam hit to PF00672, HAMP domain, score 1.5e-07 216591030838 2 probable transmembrane helices predicted for BCAM2689 by TMHMM2.0 at aa 10-32 and 185-207 216591030839 HMMPfam hit to PF02203, Tar ligand binding domain homologue, score 2.3e-08 216591030840 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 216591030841 CoenzymeA binding site [chemical binding]; other site 216591030842 subunit interaction site [polypeptide binding]; other site 216591030843 PHB binding site; other site 216591030844 HMMPfam hit to PF03061, Thioesterase superfamily, score 2.4e-12 216591030845 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591030846 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591030847 HMMPfam hit to PF02515, CoA-transferase family III, score 1.2e-53 216591030848 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 216591030849 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591030850 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 0.00045 216591030851 enoyl-CoA hydratase; Provisional; Region: PRK09245 216591030852 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591030853 substrate binding site [chemical binding]; other site 216591030854 oxyanion hole (OAH) forming residues; other site 216591030855 trimer interface [polypeptide binding]; other site 216591030856 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 1.3e-42 216591030857 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591030858 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591030859 Subunit A of Class III extradiol dioxygenases; Region: Extradiol_Dioxygenase_3A_like; cl06673 216591030860 HMMPfam hit to PF02515, CoA-transferase family III, score 3.7e-62 216591030861 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591030862 carnitinyl-CoA dehydratase; Provisional; Region: PRK03580 216591030863 substrate binding site [chemical binding]; other site 216591030864 oxyanion hole (OAH) forming residues; other site 216591030865 trimer interface [polypeptide binding]; other site 216591030866 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 5.8e-55 216591030867 PS00166 Enoyl-CoA hydratase/isomerase signature. 216591030868 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030869 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591030870 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591030871 trimer interface [polypeptide binding]; other site 216591030872 eyelet of channel; other site 216591030873 1 probable transmembrane helix predicted for BCAM2696 by TMHMM2.0 at aa 12-34 216591030874 HMMPfam hit to PF00267, Gram-negative porin, score 0.00023 216591030875 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591030876 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591030877 putative substrate translocation pore; other site 216591030878 12 probable transmembrane helices predicted for BCAM2697 by TMHMM2.0 at aa 30-52, 67-89, 102-121, 125-147, 154-176, 189-211, 257-279, 289-311, 323-342, 346-368, 380-402 and 412-431 216591030879 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 8.5e-57 216591030880 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591030881 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591030882 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 216591030883 active site 216591030884 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 9.4e-27 216591030885 PS00072 Acyl-CoA dehydrogenases signature 1. 216591030886 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 4.6e-48 216591030887 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 2.3e-15 216591030888 Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312 216591030889 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 216591030890 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 216591030891 HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 9.9e-75 216591030892 probable AcnD-accessory protein PrpF; Region: prpF; TIGR02334 216591030893 HMMPfam hit to PF04303, Protein of unknown function (DUF453), score 2.9e-276 216591030894 1 probable transmembrane helix predicted for BCAM2700 by TMHMM2.0 at aa 318-340 216591030895 2-methylisocitrate dehydratase, Fe/S-dependent; Region: 2met_isocit_dHY; TIGR02333 216591030896 Aconitase A catalytic domain; Region: AcnA_IRP; cd01586 216591030897 substrate binding site [chemical binding]; other site 216591030898 ligand binding site [chemical binding]; other site 216591030899 Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215 216591030900 substrate binding site [chemical binding]; other site 216591030901 HMMPfam hit to PF00694, Aconitase C-terminal domain, score 1.3e-31 216591030902 HMMPfam hit to PF00330, Aconitase family (aconitate hydratase), score 1.3e-145 216591030903 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591030904 Citrate synthase [Energy production and conversion]; Region: GltA; COG0372 216591030905 Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117 216591030906 dimer interface [polypeptide binding]; other site 216591030907 active site 216591030908 citrylCoA binding site [chemical binding]; other site 216591030909 oxalacetate/citrate binding site [chemical binding]; other site 216591030910 coenzyme A binding site [chemical binding]; other site 216591030911 catalytic triad [active] 216591030912 HMMPfam hit to PF00285, Citrate synthase, score 8.7e-105 216591030913 PS00480 Citrate synthase signature. 216591030914 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030915 Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714 216591030916 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 216591030917 tetramer interface [polypeptide binding]; other site 216591030918 active site 216591030919 Mg2+/Mn2+ binding site [ion binding]; other site 216591030920 Propionate catabolism activator; Region: PrpR_N; pfam06506 216591030921 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829 216591030922 PAS domain; Region: PAS; smart00091 216591030923 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591030924 Walker A motif; other site 216591030925 ATP binding site [chemical binding]; other site 216591030926 Walker B motif; other site 216591030927 arginine finger; other site 216591030928 Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420 216591030929 HMMPfam hit to PF06506, Propionate catabolism activator, score 4.7e-68 216591030930 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 2.2e-135 216591030931 HMMPfam hit to PF07728, ATPase family associated with various, score 0.00015 216591030932 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591030933 PS00017 ATP/GTP-binding site motif A (P-loop). 216591030934 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591030935 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 3.3e-09 216591030936 Predicted helix-turn-helix motif with score 1006.000, SD 2.61 at aa 617-638, sequence GDRDRACAMLGISKTTLWRKLS 216591030937 Protein of unknown function (DUF1470); Region: DUF1470; pfam07336 216591030938 CGNR zinc finger; Region: zf-CGNR; pfam11706 216591030939 HMMPfam hit to PF07336, Protein of unknown function (DUF1470), score 8.6e-34 216591030940 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262 216591030941 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591030942 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 7.8e-09 216591030943 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 216591030944 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 216591030945 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 1.6e-79 216591030946 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591030947 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 216591030948 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591030949 Predicted helix-turn-helix motif with score 1335.000, SD 3.73 at aa 45-66, sequence LTRTEITKELGRNASEIYRMLE 216591030950 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 0.00021 216591030951 acetyl coenzyme A synthetase (ADP forming), alpha domain; Region: AcCoA-syn-alpha; TIGR02717 216591030952 CoA binding domain; Region: CoA_binding_2; pfam13380 216591030953 Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607 216591030954 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 216591030955 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591030956 Coenzyme A binding pocket [chemical binding]; other site 216591030957 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1e-10 216591030958 HMMPfam hit to PF02629, CoA binding domain, score 4.1e-05 216591030959 H-NS histone family; Region: Histone_HNS; pfam00816 216591030960 Domain in histone-like proteins of HNS family; Region: HNS; smart00528 216591030961 HMMPfam hit to PF00816, H-NS histone family, score 1.2e-19 216591030962 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 7.5e-05 216591030963 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591030964 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591030965 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591030966 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-31 216591030967 PAS fold; Region: PAS_4; pfam08448 216591030968 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 216591030969 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591030970 Walker B motif; other site 216591030971 arginine finger; other site 216591030972 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 216591030973 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 3.2e-09 216591030974 Predicted helix-turn-helix motif with score 1022.000, SD 2.67 at aa 468-489, sequence GKVVEAAARIGIGRATLYKKLA 216591030975 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591030976 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3.5e-133 216591030977 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591030978 HMMPfam hit to PF08448, PAS fold, score 0.00012 216591030979 H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610 216591030980 HMMPfam hit to PF03600, Citrate transporter score 1e-112 216591030981 9 probable transmembrane helices predicted for BCAM2716 by TMHMM2.0 at aa 21-43, 58-80, 101-123, 176-198, 227-249, 282-304, 317-348, 363-385 and 443-465 216591030982 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591030983 Signal peptide predicted for BCAM2717 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.987 between residues 22 and 23 216591030984 Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098 216591030985 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591030986 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591030987 HMMPfam hit to PF00085, Thioredoxin, score 0.0029 216591030988 1 probable transmembrane helix predicted for BCAM2718 by TMHMM2.0 at aa 7-29 216591030989 putative acetyltransferase YhhY; Provisional; Region: PRK10140 216591030990 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 216591030991 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.2e-24 216591030992 phospholipase C, phosphocholine-specific, Pseudomonas-type; Region: PC_PLC; TIGR03396 216591030993 Phosphoesterase family; Region: Phosphoesterase; pfam04185 216591030994 Domain of unknown function (DUF756); Region: DUF756; pfam05506 216591030995 Domain of unknown function (DUF756); Region: DUF756; pfam05506 216591030996 HMMPfam hit to PF04185, Phosphoesterase family, score 3.6e-130 216591030997 Predicted helix-turn-helix motif with score 1119.000, SD 3.00 at aa 467-488, sequence STLRFLEKRFGVAEPQISAYRR 216591030998 HMMPfam hit to PF05506, Domain of unknown function (DUF756), score 3.9e-33 216591030999 HMMPfam hit to PF05506, Domain of unknown function (DUF756), score 4.5e-09 216591031000 SNARE associated Golgi protein; Region: SNARE_assoc; cl00429 216591031001 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 216591031002 GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444 216591031003 active site residue [active] 216591031004 5 probable transmembrane helices predicted for BCAM2722 by TMHMM2.0 at aa 13-35, 50-72, 105-127, 137-159 and 172-194 216591031005 outer membrane porin, OprD family; Region: OprD; pfam03573 216591031006 HMMPfam hit to PF03573, outer membrane porin, OprD family, score 3.1e-152 216591031007 oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079 216591031008 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591031009 Walker A/P-loop; other site 216591031010 ATP binding site [chemical binding]; other site 216591031011 Q-loop/lid; other site 216591031012 ABC transporter signature motif; other site 216591031013 Walker B; other site 216591031014 D-loop; other site 216591031015 H-loop/switch region; other site 216591031016 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 216591031017 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter C-termi, score 3.3e-28 216591031018 HMMPfam hit to PF00005, ABC transporter score 5.8e-60 216591031019 PS00211 ABC transporters family signature. 216591031020 PS00017 ATP/GTP-binding site motif A (P-loop). 216591031021 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444 216591031022 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591031023 Walker A/P-loop; other site 216591031024 ATP binding site [chemical binding]; other site 216591031025 Q-loop/lid; other site 216591031026 ABC transporter signature motif; other site 216591031027 Walker B; other site 216591031028 D-loop; other site 216591031029 H-loop/switch region; other site 216591031030 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 216591031031 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter C-termi, score 5.1e-26 216591031032 HMMPfam hit to PF00005, ABC transporter score 1.7e-62 216591031033 PS00211 ABC transporters family signature. 216591031034 PS00017 ATP/GTP-binding site motif A (P-loop). 216591031035 N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911 216591031036 oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406 216591031037 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591031038 dimer interface [polypeptide binding]; other site 216591031039 conserved gate region; other site 216591031040 putative PBP binding loops; other site 216591031041 ABC-ATPase subunit interface; other site 216591031042 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1e-45 216591031043 5 probable transmembrane helices predicted for BCAM2726 by TMHMM2.0 at aa 36-58, 105-127, 147-169, 212-234 and 266-288 216591031044 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031045 oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471 216591031046 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427 216591031047 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591031048 ABC-ATPase subunit interface; other site 216591031049 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 9.2e-46 216591031050 6 probable transmembrane helices predicted for BCAM2727 by TMHMM2.0 at aa 9-31, 99-121, 134-156, 176-195, 238-260 and 280-299 216591031051 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591031052 oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104 216591031053 The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504 216591031054 peptide binding site [polypeptide binding]; other site 216591031055 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 8.6e-75 216591031056 DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943 216591031057 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591031058 non-specific DNA binding site [nucleotide binding]; other site 216591031059 salt bridge; other site 216591031060 sequence-specific DNA binding site [nucleotide binding]; other site 216591031061 Cupin domain; Region: Cupin_2; pfam07883 216591031062 HMMPfam hit to PF05899, Protein of unknown function (DUF861), score 0.0022 216591031063 HMMPfam hit to PF07883, Cupin domain, score 2e-18 216591031064 HMMPfam hit to PF01381, Helix-turn-helix, score 3.4e-13 216591031065 Predicted helix-turn-helix motif with score 1474.000, SD 4.21 at aa 29-50, sequence RTLDDTATAAGISKPFLSQVER 216591031066 dipeptide/tripeptide permease B; Provisional; Region: PRK10207 216591031067 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591031068 putative substrate translocation pore; other site 216591031069 POT family; Region: PTR2; cl17359 216591031070 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.1e-11 216591031071 14 probable transmembrane helices predicted for BCAM2730 by TMHMM2.0 at aa 20-37, 47-69, 78-95, 100-117, 138-160, 165-187, 208-227, 232-254, 261-283, 314-336, 349-371, 381-403, 410-432 and 459-481 216591031072 HMMPfam hit to PF00854, POT family, score 2.2e-46 216591031073 OpgC protein; Region: OpgC_C; pfam10129 216591031074 10 probable transmembrane helices predicted for BCAM2731 by TMHMM2.0 at aa 24-46, 56-75, 96-118, 150-172, 177-195, 205-224, 231-253, 273-295, 308-330 and 345-367 216591031075 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031076 Predicted permeases [General function prediction only]; Region: RarD; COG2962 216591031077 Multidrug resistance efflux transporter; Region: EmrE; pfam13536 216591031078 10 probable transmembrane helices predicted for BCAM2732 by TMHMM2.0 at aa 7-24, 39-57, 77-99, 104-126, 133-150, 154-173, 180-202, 212-234, 241-263 and 268-290 216591031079 acylphosphatase; Provisional; Region: PRK14424 216591031080 HMMPfam hit to PF00708, Acylphosphatase, score 5.5e-15 216591031081 PS00151 Acylphosphatase signature 2. 216591031082 PS00150 Acylphosphatase signature 1. 216591031083 hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466 216591031084 uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs; Region: AR_FR_like_1_SDR_e; cd05228 216591031085 putative NADP binding site [chemical binding]; other site 216591031086 putative substrate binding site [chemical binding]; other site 216591031087 active site 216591031088 HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.0027 216591031089 HMMPfam hit to PF05368, NmrA-like family, score 4.1e-05 216591031090 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 4.2e-47 216591031091 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 1.4e-11 216591031092 HMMPfam hit to PF07993, Male sterility protein, score 7.5e-10 216591031093 hopene-associated glycosyltransferase HpnB; Region: HpnB; TIGR03469 216591031094 Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535 216591031095 active site 216591031096 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 216591031097 4 probable transmembrane helices predicted for BCAM2737 by TMHMM2.0 at aa 5-27, 300-322, 329-346 and 356-378 216591031098 HMMPfam hit to PF00535, Glycosyl transferase family, score 3.6e-21 216591031099 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045 216591031100 LytB protein; Region: LYTB; pfam02401 216591031101 HMMPfam hit to PF02401, LytB protein, score 1.4e-179 216591031102 hopanoid biosynthesis associated radical SAM protein HpnH; Region: HpnH; TIGR03470 216591031103 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591031104 FeS/SAM binding site; other site 216591031105 Domain of unknown function (DUF3463); Region: DUF3463; pfam11946 216591031106 HMMPfam hit to PF04055, Radical SAM superfamily, score 5.5e-20 216591031107 Dopa 4,5-dioxygenase family; Region: DOPA_dioxygen; pfam08883 216591031108 Ketosteroid isomerase homolog [Function unknown]; Region: COG4319 216591031109 Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272 216591031110 channel protein, hemolysin III family; Region: hlyIII; TIGR01065 216591031111 7 probable transmembrane helices predicted for BCAM2744 by TMHMM2.0 at aa 7-29, 39-56, 77-95, 100-122, 127-149, 153-175 and 182-204 216591031112 HMMPfam hit to PF03006, Haemolysin-III related, score 2.9e-64 216591031113 Protein of unknown function (DUF466); Region: DUF466; pfam04328 216591031114 HMMPfam hit to PF04328, Protein of unknown function (DUF466), score 3.1e-34 216591031115 carbon starvation protein A; Provisional; Region: PRK15015 216591031116 Carbon starvation protein CstA; Region: CstA; pfam02554 216591031117 C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722 216591031118 16 probable transmembrane helices predicted for BCAM2746 by TMHMM2.0 at aa 7-29, 34-53, 86-108, 118-140, 161-183, 193-210, 217-239, 254-276, 283-305, 320-342, 363-385, 463-482, 509-528, 543-565, 572-594 and 642-664 216591031119 HMMPfam hit to PF02554, Carbon starvation protein CstA, score 6.1e-255 216591031120 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031121 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031122 diaminopimelate epimerase; Provisional; Region: dapF; PRK00450 216591031123 Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678 216591031124 Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678 216591031125 HMMPfam hit to PF01678, Diaminopimelate epimerase, score 3.6e-07 216591031126 HMMPfam hit to PF01678, Diaminopimelate epimerase, score 1.8e-26 216591031127 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031128 RNA polymerase sigma-70 factor, TIGR02957 family; Region: SigX4 216591031129 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 216591031130 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 216591031131 DNA binding residues [nucleotide binding] 216591031132 HMMPfam hit to PF04542, Sigma-70 region, score 1.3e-17 216591031133 HMMPfam hit to PF08281, Sigma-70, region, score 5.6e-14 216591031134 HMMPfam hit to PF04545, Sigma-70, region, score 6.6e-06 216591031135 Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627 216591031136 Uncharacterized conserved protein [Function unknown]; Region: COG2128 216591031137 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 3.1e-22 216591031138 Cupin domain; Region: Cupin_2; pfam07883 216591031139 1 probable transmembrane helix predicted for BCAM2750 by TMHMM2.0 at aa 7-29 216591031140 HMMPfam hit to PF07883, Cupin domain, score 1.3e-16 216591031141 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591031142 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591031143 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591031144 putative effector binding pocket; other site 216591031145 dimerization interface [polypeptide binding]; other site 216591031146 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2e-18 216591031147 Predicted helix-turn-helix motif with score 1999.000, SD 6.00 at aa 36-57, sequence GSFARAADRLGVGRSSVSRHVQ 216591031148 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.7e-47 216591031149 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591031150 NADH(P)-binding; Region: NAD_binding_10; pfam13460 216591031151 NAD(P) binding site [chemical binding]; other site 216591031152 active site 216591031153 HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.0015 216591031154 HMMPfam hit to PF05368, NmrA-like family, score 6.1e-06 216591031155 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 0.00013 216591031156 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 0.003 216591031157 OsmC-like protein; Region: OsmC; cl00767 216591031158 HMMPfam hit to PF02566, OsmC-like protein, score 4.8e-27 216591031159 classical (c) SDRs; Region: SDR_c; cd05233 216591031160 NAD(P) binding site [chemical binding]; other site 216591031161 active site 216591031162 HMMPfam hit to PF00106, short chain dehydrogenase, score 6.7e-27 216591031163 1 probable transmembrane helix predicted for BCAM2754 by TMHMM2.0 at aa 27-46 216591031164 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0011 216591031165 PS00061 Short-chain dehydrogenases/reductases family signature. 216591031166 PRC-barrel domain; Region: PRC; pfam05239 216591031167 HMMPfam hit to PF05239, PRC-barrel domain, score 2.1e-08 216591031168 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591031169 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591031170 active site 216591031171 phosphorylation site [posttranslational modification] 216591031172 intermolecular recognition site; other site 216591031173 dimerization interface [polypeptide binding]; other site 216591031174 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591031175 DNA binding residues [nucleotide binding] 216591031176 dimerization interface [polypeptide binding]; other site 216591031177 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 4.7e-16 216591031178 PS00622 Bacterial regulatory proteins, luxR family signature. 216591031179 Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 190-211, sequence MSVSDIASKFSRSPKTISAQKQ 216591031180 HMMPfam hit to PF00072, Response regulator receiver domain, score 3.7e-22 216591031181 PS00017 ATP/GTP-binding site motif A (P-loop). 216591031182 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591031183 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591031184 substrate binding pocket [chemical binding]; other site 216591031185 membrane-bound complex binding site; other site 216591031186 hinge residues; other site 216591031187 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591031188 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591031189 dimer interface [polypeptide binding]; other site 216591031190 phosphorylation site [posttranslational modification] 216591031191 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591031192 ATP binding site [chemical binding]; other site 216591031193 Mg2+ binding site [ion binding]; other site 216591031194 G-X-G motif; other site 216591031195 Response regulator receiver domain; Region: Response_reg; pfam00072 216591031196 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591031197 active site 216591031198 phosphorylation site [posttranslational modification] 216591031199 intermolecular recognition site; other site 216591031200 dimerization interface [polypeptide binding]; other site 216591031201 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 4.3e-19 216591031202 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 5.6e-42 216591031203 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.6e-26 216591031204 HMMPfam hit to PF01627, Hpt domain, score 1.4e-10 216591031205 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591031206 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591031207 substrate binding pocket [chemical binding]; other site 216591031208 membrane-bound complex binding site; other site 216591031209 hinge residues; other site 216591031210 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591031211 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591031212 dimer interface [polypeptide binding]; other site 216591031213 phosphorylation site [posttranslational modification] 216591031214 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591031215 ATP binding site [chemical binding]; other site 216591031216 Mg2+ binding site [ion binding]; other site 216591031217 G-X-G motif; other site 216591031218 Response regulator receiver domain; Region: Response_reg; pfam00072 216591031219 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591031220 active site 216591031221 phosphorylation site [posttranslational modification] 216591031222 intermolecular recognition site; other site 216591031223 dimerization interface [polypeptide binding]; other site 216591031224 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.6e-28 216591031225 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 2.8e-38 216591031226 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.7e-16 216591031227 2 probable transmembrane helices predicted for BCAM2758 by TMHMM2.0 at aa 15-37 and 294-313 216591031228 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031229 CblD like pilus biogenesis initiator; Region: CblD; pfam07434 216591031230 HMMPfam hit to PF07434, CblD like pilus biogenesis initiator, score 4.1e-273 216591031231 fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310 216591031232 Predicted helix-turn-helix motif with score 983.000, SD 2.53 at aa 436-457, sequence GNTQQISIADGVSWSVYRYQMR 216591031233 CS1 type fimbrial major subunit; Region: Fimbrial_CS1; pfam04449 216591031234 HMMPfam hit to PF04449, CS1 type fimbrial major subunit, score 1.1e-92 216591031235 putative fimbrial protein TcfA; Provisional; Region: PRK15308 216591031236 phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755 216591031237 DAHP synthetase I family; Region: DAHP_synth_1; pfam00793 216591031238 HMMPfam hit to PF00793, DAHP synthetase I family, score 2.4e-147 216591031239 Secretory lipase; Region: LIP; pfam03583 216591031240 HMMPfam hit to PF03583, Secretory lipase, score 8.2e-32 216591031241 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031242 Protein of unknown function, DUF480; Region: DUF480; pfam04337 216591031243 HMMPfam hit to PF04337, Protein of unknown function, DUF480, score 5.4e-74 216591031244 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031245 short chain dehydrogenase; Provisional; Region: PRK07023 216591031246 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591031247 NAD(P) binding site [chemical binding]; other site 216591031248 active site 216591031249 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.3e-08 216591031250 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2258 216591031251 MOSC domain; Region: MOSC; pfam03473 216591031252 3-alpha domain; Region: 3-alpha; pfam03475 216591031253 HMMPfam hit to PF03473, MOSC domain, score 7.9e-45 216591031254 Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329 216591031255 Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408 216591031256 inhibitor site; inhibition site 216591031257 active site 216591031258 dimer interface [polypeptide binding]; other site 216591031259 catalytic residue [active] 216591031260 HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 8e-47 216591031261 class II aldolase/adducin domain protein; Provisional; Region: PRK07090 216591031262 intersubunit interface [polypeptide binding]; other site 216591031263 active site 216591031264 Zn2+ binding site [ion binding]; other site 216591031265 HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 1.7e-54 216591031266 PS00017 ATP/GTP-binding site motif A (P-loop). 216591031267 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591031268 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591031269 non-specific DNA binding site [nucleotide binding]; other site 216591031270 salt bridge; other site 216591031271 sequence-specific DNA binding site [nucleotide binding]; other site 216591031272 Cupin domain; Region: Cupin_2; pfam07883 216591031273 HMMPfam hit to PF01381, Helix-turn-helix, score 4.4e-17 216591031274 Predicted helix-turn-helix motif with score 1631.000, SD 4.74 at aa 14-35, sequence WTLDVLADETGLTKSYLSKVER 216591031275 HMMPfam hit to PF07883, Cupin domain, score 3.2e-15 216591031276 histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018 216591031277 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591031278 DNA-binding site [nucleotide binding]; DNA binding site 216591031279 UTRA domain; Region: UTRA; pfam07702 216591031280 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 8.5e-21 216591031281 Predicted helix-turn-helix motif with score 1291.000, SD 3.58 at aa 32-53, sequence PSELDLAAQFGVARMTVNRALR 216591031282 HMMPfam hit to PF07702, UTRA domain, score 4.2e-43 216591031283 Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312 216591031284 HMMPfam hit to PF05721, Phytanoyl-CoA dioxygenase (PhyH), score 2.9e-19 216591031285 histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437 216591031286 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591031287 substrate binding pocket [chemical binding]; other site 216591031288 membrane-bound complex binding site; other site 216591031289 hinge residues; other site 216591031290 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 6.8e-87 216591031291 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591031292 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591031293 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591031294 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591031295 dimerization interface [polypeptide binding]; other site 216591031296 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.3e-17 216591031297 Predicted helix-turn-helix motif with score 1426.000, SD 4.04 at aa 21-42, sequence GSFTTASARLHSTQSTVSQKVR 216591031298 HMMPfam hit to PF03466, LysR substrate binding domain, score 5.1e-32 216591031299 Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109 216591031300 HMMPfam hit to PF07366, SnoaL-like polyketide cyclase, score 3.6e-07 216591031301 cytosine deaminase; Provisional; Region: PRK05985 216591031302 Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293 216591031303 active site 216591031304 HMMPfam hit to PF07969, Amidohydrolase family, score 1.6e-13 216591031305 cytosine deaminase; Provisional; Region: PRK05985 216591031306 Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293 216591031307 active site 216591031308 HMMPfam hit to PF01979, Amidohydrolase family, score 0.00061 216591031309 HMMPfam hit to PF07969, Amidohydrolase family, score 4.3e-26 216591031310 Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470 216591031311 1 probable transmembrane helix predicted for BCAM2781 by TMHMM2.0 at aa 12-34 216591031312 HMMPfam hit to PF05433, Rickettsia 17 kDa surface antigen, score 2.1e-12 216591031313 Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420 216591031314 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591031315 Coenzyme A binding pocket [chemical binding]; other site 216591031316 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.6e-19 216591031317 Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434 216591031318 Probable polygalacturonase At3g15720; Region: PLN03003; cl14103 216591031319 HMMPfam hit to PF00295, Glycosyl hydrolases family, score 1.1e-05 216591031320 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031321 PS00502 Polygalacturonase active site. 216591031322 aminotransferase; Validated; Region: PRK07046 216591031323 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 216591031324 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591031325 catalytic residue [active] 216591031326 HMMPfam hit to PF00202, Aminotransferase class-III, score 7.4e-14 216591031327 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 216591031328 M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666 216591031329 metal binding site [ion binding]; metal-binding site 216591031330 putative dimer interface [polypeptide binding]; other site 216591031331 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 5e-58 216591031332 diaminopropionate ammonia-lyase; Provisional; Region: PRK08206 216591031333 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 216591031334 catalytic residue [active] 216591031335 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 4.1e-26 216591031336 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591031337 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591031338 putative DNA binding site [nucleotide binding]; other site 216591031339 putative Zn2+ binding site [ion binding]; other site 216591031340 AsnC family; Region: AsnC_trans_reg; pfam01037 216591031341 Predicted helix-turn-helix motif with score 1571.000, SD 4.54 at aa 22-43, sequence TPQAELGARVNLSTAAVNRRLR 216591031342 PS00519 Bacterial regulatory proteins, asnC family signature. 216591031343 HMMPfam hit to PF01037, AsnC family, score 3.5e-22 216591031344 Tannase and feruloyl esterase; Region: Tannase; pfam07519 216591031345 HMMPfam hit to PF07519, Tannase and feruloyl esterase, score 6.1e-147 216591031346 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591031347 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591031348 trimer interface [polypeptide binding]; other site 216591031349 eyelet of channel; other site 216591031350 HMMPfam hit to PF00267, Gram-negative porin, score 1.7e-05 216591031351 putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551 216591031352 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591031353 putative substrate translocation pore; other site 216591031354 HMMPfam hit to PF00083, Sugar (and other) transporter score 3.1e-05 216591031355 12 probable transmembrane helices predicted for BCAM2790 by TMHMM2.0 at aa 13-35, 45-67, 80-99, 104-126, 139-161, 166-188, 221-240, 255-277, 284-306, 310-332, 345-367 and 372-394 216591031356 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.1e-51 216591031357 PS00217 Sugar transport proteins signature 2. 216591031358 PS00216 Sugar transport proteins signature 1. 216591031359 feruloyl-CoA synthase; Reviewed; Region: PRK08180 216591031360 Feruloyl-CoA synthetase (FCS); Region: FCS; cd05921 216591031361 acyl-activating enzyme (AAE) consensus motif; other site 216591031362 putative AMP binding site [chemical binding]; other site 216591031363 putative active site [active] 216591031364 putative CoA binding site [chemical binding]; other site 216591031365 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.2e-59 216591031366 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591031367 Salicylaldehyde dehydrogenase, DoxF-like; Region: ALDH_SaliADH; cd07105 216591031368 NAD(P) binding site [chemical binding]; other site 216591031369 catalytic residues [active] 216591031370 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 4.3e-190 216591031371 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591031372 p-hydroxycinnamoyl CoA hydratase/lyase; Validated; Region: PRK09120 216591031373 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 216591031374 substrate binding site [chemical binding]; other site 216591031375 oxyanion hole (OAH) forming residues; other site 216591031376 trimer interface [polypeptide binding]; other site 216591031377 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 9.7e-43 216591031378 PS00166 Enoyl-CoA hydratase/isomerase signature. 216591031379 Transcriptional regulators [Transcription]; Region: MarR; COG1846 216591031380 MarR family; Region: MarR_2; pfam12802 216591031381 HMMPfam hit to PF01047, MarR family, score 1.5e-10 216591031382 SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450 216591031383 HMMPfam hit to PF08450, SMP-30/Gluconolaconase/LRE-like region, score 3.3e-35 216591031384 HMMPfam hit to PF03758, Senescence marker protein-30 (SMP-30), N-ter, score 3.2e-23 216591031385 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591031386 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591031387 TM-ABC transporter signature motif; other site 216591031388 10 probable transmembrane helices predicted for BCAM2796 by TMHMM2.0 at aa 27-49, 59-81, 86-105, 109-131, 136-155, 175-197, 202-224, 229-248, 261-292 and 307-324 216591031389 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.3e-52 216591031390 L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288 216591031391 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 216591031392 Walker A/P-loop; other site 216591031393 ATP binding site [chemical binding]; other site 216591031394 Q-loop/lid; other site 216591031395 ABC transporter signature motif; other site 216591031396 Walker B; other site 216591031397 D-loop; other site 216591031398 H-loop/switch region; other site 216591031399 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 216591031400 HMMPfam hit to PF00005, ABC transporter score 3.2e-30 216591031401 PS00211 ABC transporters family signature. 216591031402 HMMPfam hit to PF00005, ABC transporter score 2.8e-60 216591031403 PS00017 ATP/GTP-binding site motif A (P-loop). 216591031404 Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532 216591031405 Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540 216591031406 ligand binding site [chemical binding]; other site 216591031407 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 1.1e-35 216591031408 1 probable transmembrane helix predicted for BCAM2798 by TMHMM2.0 at aa 13-35 216591031409 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 216591031410 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 216591031411 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 0.01 216591031412 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 3.3e-28 216591031413 Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329 216591031414 Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408 216591031415 inhibitor site; inhibition site 216591031416 active site 216591031417 dimer interface [polypeptide binding]; other site 216591031418 catalytic residue [active] 216591031419 HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 3.5e-11 216591031420 dihydroxy-acid dehydratase; Validated; Region: PRK06131 216591031421 HMMPfam hit to PF00920, Dehydratase family, score 1.2e-227 216591031422 PS00017 ATP/GTP-binding site motif A (P-loop). 216591031423 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031424 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031425 PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 216591031426 pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424 216591031427 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591031428 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591031429 dimerization interface [polypeptide binding]; other site 216591031430 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.1e-18 216591031431 Predicted helix-turn-helix motif with score 1579.000, SD 4.56 at aa 28-49, sequence GSIHRAAAALNMTQPAASKLLR 216591031432 PS00044 Bacterial regulatory proteins, lysR family signature. 216591031433 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.3e-35 216591031434 PS00307 Legume lectins beta-chain signature. 216591031435 Organic hydroperoxide reductase [Secondary metabolites biosynthesis, transport and catabolism]; Region: osmC; COG1764 216591031436 HMMPfam hit to PF02566, OsmC-like protein, score 2.7e-25 216591031437 Transcriptional regulators [Transcription]; Region: GntR; COG1802 216591031438 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591031439 DNA-binding site [nucleotide binding]; DNA binding site 216591031440 FCD domain; Region: FCD; pfam07729 216591031441 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 4.3e-23 216591031442 Predicted helix-turn-helix motif with score 1013.000, SD 2.64 at aa 51-72, sequence LVERDLAERFGISRIPMREAIQ 216591031443 HMMPfam hit to PF07729, FCD domain, score 1.4e-10 216591031444 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591031445 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591031446 DNA binding site [nucleotide binding] 216591031447 domain linker motif; other site 216591031448 Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267 216591031449 dimerization interface [polypeptide binding]; other site 216591031450 ligand binding site [chemical binding]; other site 216591031451 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 5.3e-13 216591031452 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 1.3e-08 216591031453 Predicted helix-turn-helix motif with score 1741.000, SD 5.12 at aa 2-23, sequence ATLDEVARRAGVTAATVSNVLR 216591031454 PS00356 Bacterial regulatory proteins, lacI family signature. 216591031455 maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000 216591031456 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 216591031457 Walker A/P-loop; other site 216591031458 ATP binding site [chemical binding]; other site 216591031459 Q-loop/lid; other site 216591031460 ABC transporter signature motif; other site 216591031461 Walker B; other site 216591031462 D-loop; other site 216591031463 H-loop/switch region; other site 216591031464 TOBE domain; Region: TOBE_2; pfam08402 216591031465 HMMPfam hit to PF00005, ABC transporter score 2.3e-48 216591031466 PS00017 ATP/GTP-binding site motif A (P-loop). 216591031467 PS00211 ABC transporters family signature. 216591031468 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031469 HMMPfam hit to PF08402, TOBE domain, score 1.1e-10 216591031470 HMMPfam hit to PF03459, TOBE domain, score 1.8e-05 216591031471 Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874 216591031472 Beta-galactosidase; Region: Glyco_hydro_42; pfam02449 216591031473 A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143 216591031474 HMMPfam hit to PF02449, Beta-galactosidase, score 6.5e-215 216591031475 HMMPfam hit to PF08532, Beta-galactosidase trimerisation doma, score 2.9e-51 216591031476 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 216591031477 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 216591031478 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 2.2e-37 216591031479 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 216591031480 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591031481 dimer interface [polypeptide binding]; other site 216591031482 putative PBP binding loops; other site 216591031483 ABC-ATPase subunit interface; other site 216591031484 6 probable transmembrane helices predicted for BCAM2809 by TMHMM2.0 at aa 20-42, 77-99, 111-130, 157-179, 200-222 and 258-280 216591031485 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.00086 216591031486 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 216591031487 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591031488 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 216591031489 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591031490 dimer interface [polypeptide binding]; other site 216591031491 conserved gate region; other site 216591031492 putative PBP binding loops; other site 216591031493 ABC-ATPase subunit interface; other site 216591031494 7 probable transmembrane helices predicted for BCAM2810 by TMHMM2.0 at aa 21-43, 81-103, 110-132, 147-169, 190-212, 217-239 and 246-268 216591031495 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 9.5e-19 216591031496 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591031497 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591031498 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591031499 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591031500 dimerization interface [polypeptide binding]; other site 216591031501 substrate binding pocket [chemical binding]; other site 216591031502 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.8e-15 216591031503 Predicted helix-turn-helix motif with score 1552.000, SD 4.47 at aa 42-63, sequence GSVSKAADHLCRTQGAVSRQIQ 216591031504 PS00044 Bacterial regulatory proteins, lysR family signature. 216591031505 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.5e-24 216591031506 ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192 216591031507 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 216591031508 ATP binding site [chemical binding]; other site 216591031509 Mg++ binding site [ion binding]; other site 216591031510 motif III; other site 216591031511 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 216591031512 nucleotide binding region [chemical binding]; other site 216591031513 ATP-binding site [chemical binding]; other site 216591031514 PS00017 ATP/GTP-binding site motif A (P-loop). 216591031515 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1.9e-32 216591031516 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 4.3e-68 216591031517 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 1.9e-05 216591031518 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 216591031519 PS00017 ATP/GTP-binding site motif A (P-loop). 216591031520 Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070 216591031521 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 216591031522 FMN binding site [chemical binding]; other site 216591031523 substrate binding site [chemical binding]; other site 216591031524 putative catalytic residue [active] 216591031525 HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 2.3e-63 216591031526 PS00912 Dihydroorotate dehydrogenase signature 2. 216591031527 DNA-binding transcriptional regulator GlcC; Provisional; Region: PRK09990 216591031528 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591031529 DNA-binding site [nucleotide binding]; DNA binding site 216591031530 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 216591031531 HMMPfam hit to PF07729, FCD domain, score 1.9e-36 216591031532 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 1.5e-17 216591031533 PS00043 Bacterial regulatory proteins, gntR family signature. 216591031534 glycolate oxidase subunit GlcD; Provisional; Region: PRK11230 216591031535 FAD binding domain; Region: FAD_binding_4; pfam01565 216591031536 HMMPfam hit to PF01565, FAD binding domain, score 3.8e-57 216591031537 HMMPfam hit to PF02913, FAD linked oxidases, C-terminal domain, score 4.5e-89 216591031538 FAD binding domain; Region: FAD_binding_4; pfam01565 216591031539 glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282 216591031540 HMMPfam hit to PF01565, FAD binding domain, score 7.5e-17 216591031541 glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274 216591031542 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 216591031543 Cysteine-rich domain; Region: CCG; pfam02754 216591031544 Cysteine-rich domain; Region: CCG; pfam02754 216591031545 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.011 216591031546 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591031547 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00075 216591031548 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591031549 HMMPfam hit to PF02754, Cysteine-rich domain, score 6.3e-07 216591031550 HMMPfam hit to PF02754, Cysteine-rich domain, score 2.4e-15 216591031551 Domain of unknown function (DUF336); Region: DUF336; cl01249 216591031552 HMMPfam hit to PF03928, Domain of unknown function (DUF336), score 4.4e-47 216591031553 malate synthase G; Provisional; Region: PRK02999 216591031554 active site 216591031555 HMMPfam hit to PF01274, Malate synthase, score 0 216591031556 Cache domain; Region: Cache_1; pfam02743 216591031557 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591031558 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591031559 metal binding site [ion binding]; metal-binding site 216591031560 active site 216591031561 I-site; other site 216591031562 2 probable transmembrane helices predicted for BCAM2822 by TMHMM2.0 at aa 22-44 and 299-321 216591031563 HMMPfam hit to PF00990, GGDEF domain, score 4.1e-67 216591031564 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4564 216591031565 Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049 216591031566 Histidine kinase; Region: HisKA_3; pfam07730 216591031567 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591031568 ATP binding site [chemical binding]; other site 216591031569 Mg2+ binding site [ion binding]; other site 216591031570 G-X-G motif; other site 216591031571 2 probable transmembrane helices predicted for BCAM2823 by TMHMM2.0 at aa 7-26 and 208-230 216591031572 HMMPfam hit to PF08269, Cache domain, score 5.2e-27 216591031573 HMMPfam hit to PF07730, Histidine kinase, score 2.1e-17 216591031574 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.5e-19 216591031575 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591031576 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591031577 active site 216591031578 phosphorylation site [posttranslational modification] 216591031579 intermolecular recognition site; other site 216591031580 dimerization interface [polypeptide binding]; other site 216591031581 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591031582 DNA binding residues [nucleotide binding] 216591031583 dimerization interface [polypeptide binding]; other site 216591031584 HMMPfam hit to PF00072, Response regulator receiver domain, score 5.2e-32 216591031585 HMMPfam hit to PF08281, Sigma-70, region, score 5.5e-07 216591031586 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 1.4e-20 216591031587 PS00622 Bacterial regulatory proteins, luxR family signature. 216591031588 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591031589 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591031590 putative substrate translocation pore; other site 216591031591 14 probable transmembrane helices predicted for BCAM2825 by TMHMM2.0 at aa 7-29, 44-66, 75-97, 102-121, 134-156, 166-185, 198-217, 227-245, 266-288, 298-320, 327-349, 353-375, 396-418 and 461-483 216591031592 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.9e-59 216591031593 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031594 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591031595 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591031596 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 4.2e-18 216591031597 PS01081 Bacterial regulatory proteins, tetR family signature. 216591031598 Predicted helix-turn-helix motif with score 1079.000, SD 2.86 at aa 58-79, sequence TTISEIVEHAQVAKGTFYHYFE 216591031599 Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; pfam05494 216591031600 HMMPfam hit to PF05494, Toluene tolerance, Ttg2, score 1.2e-36 216591031601 hopanoid biosynthesis associated RND transporter like protein HpnN; Region: HpnN; TIGR03480 216591031602 12 probable transmembrane helices predicted for BCAM2828 by TMHMM2.0 at aa 17-39, 277-296, 303-325, 329-351, 371-393, 403-425, 457-479, 717-739, 746-768, 773-795, 808-830 and 840-859 216591031603 VacJ like lipoprotein; Region: VacJ; cl01073 216591031604 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031605 HMMPfam hit to PF04333, VacJ like lipoprotein, score 2.1e-84 216591031606 hypothetical protein; Provisional; Region: PRK07077 216591031607 squalene-hopene cyclase; Region: hopene_cyclase; TIGR01507 216591031608 Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; Region: SQCY_1; cd02892 216591031609 Active site cavity [active] 216591031610 catalytic acid [active] 216591031611 HMMPfam hit to PF00432, Prenyltransferase and squalene oxidase re, score 8e-09 216591031612 HMMPfam hit to PF00432, Prenyltransferase and squalene oxidase re, score 5e-10 216591031613 PS01074 Terpene synthases signature. 216591031614 HMMPfam hit to PF00432, Prenyltransferase and squalene oxidase re, score 6e-07 216591031615 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 216591031616 squalene-associated FAD-dependent desaturase; Region: HpnE; TIGR03467 216591031617 HMMPfam hit to PF01593, Flavin containing amine oxidoreductase, score 1.5e-26 216591031618 Predicted helix-turn-helix motif with score 1024.000, SD 2.67 at aa 317-338, sequence ATIRDAGRWLDMPRDTLARRIW 216591031619 Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683 216591031620 active site lid residues [active] 216591031621 substrate binding pocket [chemical binding]; other site 216591031622 catalytic residues [active] 216591031623 substrate-Mg2+ binding site; other site 216591031624 aspartate-rich region 1; other site 216591031625 aspartate-rich region 2; other site 216591031626 HMMPfam hit to PF00494, Squalene/phytoene synthase, score 1.1e-23 216591031627 PS01045 Squalene and phytoene synthases signature 2. 216591031628 methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657 216591031629 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591031630 PS00120 Lipases, serine active site. 216591031631 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591031632 PAS domain; Region: PAS_9; pfam13426 216591031633 putative active site [active] 216591031634 heme pocket [chemical binding]; other site 216591031635 Putative heavy-metal-binding; Region: YbjQ_1; cl00426 216591031636 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591031637 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591031638 metal binding site [ion binding]; metal-binding site 216591031639 active site 216591031640 I-site; other site 216591031641 HMMPfam hit to PF00990, GGDEF domain, score 1.3e-58 216591031642 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031643 Putative pseudogene. May also be transcribed as two separate CDS 216591031644 PS00216 Sugar transport proteins signature 1. 216591031645 HMMPfam hit to PF04509, CheC-like family, score 1.1e-05 216591031646 HMMPfam hit to PF00072, Response regulator receiver domain, score 4.5e-24 216591031647 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591031648 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591031649 dimer interface [polypeptide binding]; other site 216591031650 phosphorylation site [posttranslational modification] 216591031651 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591031652 ATP binding site [chemical binding]; other site 216591031653 Mg2+ binding site [ion binding]; other site 216591031654 G-X-G motif; other site 216591031655 Response regulator receiver domain; Region: Response_reg; pfam00072 216591031656 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591031657 active site 216591031658 phosphorylation site [posttranslational modification] 216591031659 intermolecular recognition site; other site 216591031660 dimerization interface [polypeptide binding]; other site 216591031661 1 probable transmembrane helix predicted for BCAM2839 by TMHMM2.0 at aa 40-62 216591031662 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.00033 216591031663 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 8.2e-24 216591031664 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.9e-20 216591031665 Predicted flavoprotein [General function prediction only]; Region: COG0431 216591031666 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591031667 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 5.7e-30 216591031668 Initiator Replication protein; Region: Rep_3; pfam01051 216591031669 ParB-like nuclease domain; Region: ParB; smart00470 216591031670 ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180 216591031671 HMMPfam hit to PF02195, ParB-like nuclease domain, score 1.3e-10 216591031672 ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192 216591031673 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 216591031674 P-loop; other site 216591031675 Magnesium ion binding site [ion binding]; other site 216591031676 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 1.5e-22 216591031677 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591031678 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591031679 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591031680 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591031681 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031682 HMMPfam hit to PF01548, Transposase, score 2.9e-12 216591031683 AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719 216591031684 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591031685 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591031686 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.7e-13 216591031687 PS00041 Bacterial regulatory proteins, araC family signature. 216591031688 Predicted helix-turn-helix motif with score 1047.000, SD 2.75 at aa 239-260, sequence LRVDDLAAQVQMSSSTFHHHFR 216591031689 HMMPfam hit to PF06719, AraC-type transcriptional regulator N-termin, score 2.8e-65 216591031690 Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220 216591031691 Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706 216591031692 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591031693 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591031694 AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246 216591031695 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.1e-20 216591031696 Predicted helix-turn-helix motif with score 1610.000, SD 4.67 at aa 34-55, sequence TSMDRIAARADVSKRTVYNHFP 216591031697 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 216591031698 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 216591031699 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591031700 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 0.0032 216591031701 Protein of unknown function (DUF2889); Region: DUF2889; pfam11136 216591031702 ProQ/FINO family; Region: ProQ; pfam04352 216591031703 Activator of osmoprotectant transporter ProP [Signal transduction mechanisms]; Region: ProQ; COG3109 216591031704 HMMPfam hit to PF04352, ProQ activator of osmoprotectant transporter, score 1.6e-28 216591031705 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 216591031706 EamA-like transporter family; Region: EamA; pfam00892 216591031707 10 probable transmembrane helices predicted for BCAS0011 by TMHMM2.0 at aa 7-29, 33-55, 76-98, 103-125, 132-149, 154-172, 185-207, 217-239, 246-268 and 272-289 216591031708 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 3.7e-15 216591031709 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031710 NifQ; Region: NifQ; pfam04891 216591031711 HMMPfam hit to PF04891, NifQ, score 8.5e-18 216591031712 TOBE domain; Region: TOBE; cl01440 216591031713 TOBE domain; Region: TOBE; cl01440 216591031714 HMMPfam hit to PF03459, TOBE domain, score 1.7e-13 216591031715 HMMPfam hit to PF03459, TOBE domain, score 1e-16 216591031716 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591031717 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1e-25 216591031718 HMMPfam hit to PF02321, Outer membrane efflux protein, score 5.1e-18 216591031719 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031720 Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566 216591031721 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591031722 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591031723 HMMPfam hit to PF00529, HlyD family secretion protein, score 4.9e-16 216591031724 1 probable transmembrane helix predicted for BCAS0015 by TMHMM2.0 at aa 7-29 216591031725 Protein of unknown function (DUF1656); Region: DUF1656; pfam07869 216591031726 HMMPfam hit to PF07869, Protein of unknown function (DUF1656), score 7.7e-21 216591031727 2 probable transmembrane helices predicted for BCAS0016 by TMHMM2.0 at aa 7-29 and 41-63 216591031728 Fusaric acid resistance protein family; Region: FUSC; pfam04632 216591031729 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 216591031730 9 probable transmembrane helices predicted for BCAS0017 by TMHMM2.0 at aa 15-37, 56-78, 82-101, 108-125, 135-157, 369-391, 420-442, 449-468 and 495-517 216591031731 HMMPfam hit to PF04632, Fusaric acid resistance protein conserved re, score 4.3e-15 216591031732 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031733 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031734 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 216591031735 Winged helix DNA-binding domain; Region: HTH_27; pfam13463 216591031736 HMMPfam hit to PF01047, MarR family, score 4.6e-08 216591031737 The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509 216591031738 Uncharacterized conserved protein [Function unknown]; Region: COG3777 216591031739 The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509 216591031740 active site 2 [active] 216591031741 active site 1 [active] 216591031742 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591031743 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591031744 active site 216591031745 HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal doma, score 1.9e-13 216591031746 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 1.3e-22 216591031747 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 5.2e-37 216591031748 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 7e-07 216591031749 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031750 PS00073 Acyl-CoA dehydrogenases signature 2. 216591031751 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591031752 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591031753 HMMPfam hit to PF02515, CoA-transferase family III, score 4.1e-59 216591031754 MmgE/PrpD family; Region: MmgE_PrpD; cl00912 216591031755 HMMPfam hit to PF03972, MmgE/PrpD family, score 1.5e-111 216591031756 Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301 216591031757 HMMPfam hit to PF03328, HpcH/HpaI aldolase/citrate lyase family, score 2.2e-33 216591031758 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591031759 DNA-binding site [nucleotide binding]; DNA binding site 216591031760 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 216591031761 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591031762 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591031763 homodimer interface [polypeptide binding]; other site 216591031764 catalytic residue [active] 216591031765 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 9.5e-13 216591031766 Predicted helix-turn-helix motif with score 1454.000, SD 4.14 at aa 47-68, sequence APQRDVASSLGVSVQTVTNAYK 216591031767 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.1e-07 216591031768 hypothetical protein; Provisional; Region: PRK06815 216591031769 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 216591031770 tetramer interface [polypeptide binding]; other site 216591031771 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591031772 catalytic residue [active] 216591031773 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 6.2e-69 216591031774 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 216591031775 ectoine utilization protein EutC; Validated; Region: PRK08291 216591031776 ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400 216591031777 HMMPfam hit to PF02423, Ornithine cyclodeaminase/mu-crystalli, score 1.1e-93 216591031778 HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase, score 7e-06 216591031779 ectoine utilization protein EutD; Region: ectoine_eutD; TIGR02993 216591031780 Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321 216591031781 A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066 216591031782 active site 216591031783 HMMPfam hit to PF00557, metallopeptidase family M24, score 5.7e-08 216591031784 ectoine utilization protein EutE; Region: ectoine_eutE; TIGR02994 216591031785 Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup; Region: M14_ASTE_ASPA_like_2; cd06252 216591031786 putative active site [active] 216591031787 Zn binding site [ion binding]; other site 216591031788 HMMPfam hit to PF04952, Succinylglutamate desuccinylase / Aspartoac, score 2.2e-99 216591031789 PS00107 Protein kinases ATP-binding region signature. 216591031790 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591031791 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591031792 putative DNA binding site [nucleotide binding]; other site 216591031793 putative Zn2+ binding site [ion binding]; other site 216591031794 AsnC family; Region: AsnC_trans_reg; pfam01037 216591031795 Predicted helix-turn-helix motif with score 1095.000, SD 2.92 at aa 21-42, sequence ITKSKLAEAVNLSISPAWERVR 216591031796 HMMPfam hit to PF01037, AsnC family, score 1.1e-24 216591031797 succinic semialdehyde dehydrogenase; Region: PLN02278 216591031798 Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103 216591031799 tetramerization interface [polypeptide binding]; other site 216591031800 NAD(P) binding site [chemical binding]; other site 216591031801 catalytic residues [active] 216591031802 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1e-198 216591031803 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591031804 PS00070 Aldehyde dehydrogenases cysteine active site. 216591031805 hypothetical protein; Provisional; Region: PRK07482 216591031806 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591031807 inhibitor-cofactor binding pocket; inhibition site 216591031808 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591031809 catalytic residue [active] 216591031810 HMMPfam hit to PF00202, Aminotransferase class-III, score 9.3e-74 216591031811 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591031812 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591031813 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591031814 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591031815 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591031816 Predicted helix-turn-helix motif with score 1703.000, SD 4.99 at aa 20-41, sequence EAIRAVARTHGLSHSTVSQWYA 216591031817 putative transposase OrfB; Reviewed; Region: PHA02517 216591031818 HTH-like domain; Region: HTH_21; pfam13276 216591031819 Integrase core domain; Region: rve; pfam00665 216591031820 Integrase core domain; Region: rve_2; pfam13333 216591031821 HMMPfam hit to PF00665, Integrase core domain, score 5.1e-42 216591031822 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 216591031823 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 2.1e-19 216591031824 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591031825 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591031826 putative substrate translocation pore; other site 216591031827 HMMPfam hit to PF00083, Sugar (and other) transporter, score 9.8e-33 216591031828 12 probable transmembrane helices predicted for BCAS0035 by TMHMM2.0 at aa 50-67, 72-94, 106-128, 138-160, 173-195, 205-227, 265-287, 302-324, 331-350, 360-382, 395-417 and 422-444 216591031829 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031830 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3e-25 216591031831 PS00216 Sugar transport proteins signature 1. 216591031832 PS00217 Sugar transport proteins signature 2. 216591031833 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 216591031834 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591031835 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 216591031836 dimerization interface [polypeptide binding]; other site 216591031837 substrate binding pocket [chemical binding]; other site 216591031838 HMMPfam hit to PF03466, LysR substrate binding domain, score 7e-37 216591031839 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031840 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.2e-25 216591031841 PS00044 Bacterial regulatory proteins, lysR family signature. 216591031842 Predicted helix-turn-helix motif with score 1579.000, SD 4.56 at aa 16-37, sequence GSFTRAASELGIAQPALSQALN 216591031843 benzoate transport; Region: 2A0115; TIGR00895 216591031844 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591031845 putative substrate translocation pore; other site 216591031846 HMMPfam hit to PF00083, Sugar (and other) transporter, score 2.1e-07 216591031847 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.9e-42 216591031848 12 probable transmembrane helices predicted for BCAS0037 by TMHMM2.0 at aa 20-42, 52-71, 78-100, 110-132, 145-164, 168-187, 222-244, 254-276, 288-307, 312-334, 347-369 and 374-396 216591031849 PS00217 Sugar transport proteins signature 2. 216591031850 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031851 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 216591031852 active site 216591031853 HMMPfam hit to PF04909, Amidohydrolase, score 4.2e-47 216591031854 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031855 Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714 216591031856 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 216591031857 tetramer interface [polypeptide binding]; other site 216591031858 active site 216591031859 Mg2+/Mn2+ binding site [ion binding]; other site 216591031860 alpha-ketoglutarate transporter; Provisional; Region: PRK10406 216591031861 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591031862 putative substrate translocation pore; other site 216591031863 HMMPfam hit to PF00083, Sugar (and other) transporter, score 2.7e-31 216591031864 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.5e-13 216591031865 11 probable transmembrane helices predicted for BCAS0040 by TMHMM2.0 at aa 27-49, 56-78, 102-124, 153-175, 190-209, 242-262, 277-299, 308-330, 335-357, 369-391 and 401-418 216591031866 PS00217 Sugar transport proteins signature 2. 216591031867 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 216591031868 FeS/SAM binding site; other site 216591031869 HMMPfam hit to PF04055, Radical SAM superfamily, score 0.016 216591031870 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591031871 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591031872 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 9.8e-40 216591031873 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031874 PS00261 Glycoprotein hormones beta chain signature 1. 216591031875 L-lysine 6-monooxygenase (NADPH-requiring); Region: K_oxygenase; pfam13434 216591031876 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 216591031877 ATP-grasp domain; Region: ATP-grasp_4; pfam13535 216591031878 HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase, ATP-gr, score 4.7e-05 216591031879 methionyl-tRNA synthetase; Reviewed; Region: PRK11893 216591031880 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 216591031881 active site 216591031882 nucleotide binding site [chemical binding]; other site 216591031883 HIGH motif; other site 216591031884 KMSKS motif; other site 216591031885 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 216591031886 PS00356 Bacterial regulatory proteins, lacI family signature. 216591031887 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591031888 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591031889 PS00017 ATP/GTP-binding site motif A (P-loop). 216591031890 HMMPfam hit to PF02515, CoA-transferase family III, score 4e-62 216591031891 Cupin domain; Region: Cupin_2; pfam07883 216591031892 HMMPfam hit to PF07883, Cupin domain, score 2.5e-15 216591031893 FAD dependent oxidoreductase; Region: DAO; pfam01266 216591031894 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 4.8e-08 216591031895 Predicted permeases [General function prediction only]; Region: COG0679 216591031896 HMMPfam hit to PF03547, Auxin Efflux Carrier, score 6.1e-07 216591031897 9 probable transmembrane helices predicted for BCAS0049 by TMHMM2.0 at aa 5-27, 40-57, 67-89, 102-119, 124-146, 159-181, 196-216, 223-245 and 282-304 216591031898 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591031899 Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618 216591031900 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 216591031901 active site 216591031902 HMMPfam hit to PF04909, Amidohydrolase, score 5.3e-46 216591031903 dihydroxyacetone kinase; Provisional; Region: PRK14479 216591031904 dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557 216591031905 DAK2 domain; Region: Dak2; pfam02734 216591031906 HMMPfam hit to PF02734, DAK2 domain, score 3.4e-55 216591031907 HMMPfam hit to PF02733, Dak1 domain, score 2.3e-138 216591031908 psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974 216591031909 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591031910 Walker A motif; other site 216591031911 ATP binding site [chemical binding]; other site 216591031912 Walker B motif; other site 216591031913 arginine finger; other site 216591031914 Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420 216591031915 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 0.0013 216591031916 Predicted helix-turn-helix motif with score 1247.000, SD 3.43 at aa 315-336, sequence RNQIRAAQLLGISRNVLRARLI 216591031917 PS00688 Sigma-54 interaction domain C-terminal part signature. 216591031918 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 8.6e-144 216591031919 HMMPfam hit to PF07728, ATPase family associated with various, score 0.0002 216591031920 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216591031921 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 216591031922 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591031923 FMN reductase, MsuE subfamily; Region: FMN_reduc_MsuE; TIGR03566 216591031924 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 3.3e-09 216591031925 dimethyl sulfone monooxygenase SfnG; Region: LLM_DMSO2_sfnG; TIGR04021 216591031926 Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094 216591031927 active site 216591031928 dimer interface [polypeptide binding]; other site 216591031929 non-prolyl cis peptide bond; other site 216591031930 insertion regions; other site 216591031931 Formyltransferase, catalytic core domain; Region: FMT_core; cl00395 216591031932 cosubstrate binding site; other site 216591031933 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 3.5e-07 216591031934 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 216591031935 HMMPfam hit to PF01810, LysE type translocator, score 1.5e-16 216591031936 6 probable transmembrane helices predicted for BCAS0055 by TMHMM2.0 at aa 5-27, 40-62, 67-89, 113-135, 150-172 and 184-206 216591031937 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591031938 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591031939 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591031940 dimerization interface [polypeptide binding]; other site 216591031941 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2e-18 216591031942 Predicted helix-turn-helix motif with score 1449.000, SD 4.12 at aa 19-40, sequence GSFAQGAQAVHRSPSAVSMQIR 216591031943 PS00044 Bacterial regulatory proteins, lysR family signature. 216591031944 HMMPfam hit to PF03466, LysR substrate binding domain, score 1e-23 216591031945 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591031946 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591031947 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591031948 dimerization interface [polypeptide binding]; other site 216591031949 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.3e-36 216591031950 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 7.5e-23 216591031951 PS00044 Bacterial regulatory proteins, lysR family signature. 216591031952 Predicted helix-turn-helix motif with score 1934.000, SD 5.77 at aa 23-44, sequence ESYTRAADELSLSQSAISRQVQ 216591031953 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 216591031954 FAD binding domain; Region: FAD_binding_4; pfam01565 216591031955 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 216591031956 HMMPfam hit to PF01565, FAD binding domain, score 5.3e-48 216591031957 PS00017 ATP/GTP-binding site motif A (P-loop). 216591031958 HMMPfam hit to PF02913, FAD linked oxidases, C-terminal domain, score 1.8e-61 216591031959 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591031960 Predicted helix-turn-helix motif with score 1124.000, SD 3.02 at aa 18-39, sequence LTAREFARLIRMNESSITNYSS 216591031961 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 216591031962 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 216591031963 dimerization interface [polypeptide binding]; other site 216591031964 ligand binding site [chemical binding]; other site 216591031965 HMMPfam hit to PF01094, Receptor family ligand binding region, score 1.2e-65 216591031966 putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272 216591031967 EamA-like transporter family; Region: EamA; pfam00892 216591031968 EamA-like transporter family; Region: EamA; pfam00892 216591031969 10 probable transmembrane helices predicted for BCAS0061 by TMHMM2.0 at aa 16-38, 48-65, 77-94, 104-126, 133-152, 156-178, 185-207, 222-244, 253-272 and 276-295 216591031970 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2e-21 216591031971 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.1e-31 216591031972 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591031973 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591031974 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591031975 dimerization interface [polypeptide binding]; other site 216591031976 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.6e-17 216591031977 Predicted helix-turn-helix motif with score 1133.000, SD 3.05 at aa 21-42, sequence GSFLAAADVSGVTHGAISRRVA 216591031978 PS00044 Bacterial regulatory proteins, lysR family signature. 216591031979 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.1e-21 216591031980 4 probable transmembrane helices predicted for BCAS0064 by TMHMM2.0 at aa 7-29, 64-86, 98-120 and 130-149 216591031981 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 216591031982 GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047 216591031983 putative C-terminal domain interface [polypeptide binding]; other site 216591031984 putative GSH binding site (G-site) [chemical binding]; other site 216591031985 putative dimer interface [polypeptide binding]; other site 216591031986 C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180 216591031987 putative N-terminal domain interface [polypeptide binding]; other site 216591031988 putative dimer interface [polypeptide binding]; other site 216591031989 putative substrate binding pocket (H-site) [chemical binding]; other site 216591031990 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 4e-11 216591031991 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 1.1e-07 216591031992 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591031993 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591031994 trimer interface [polypeptide binding]; other site 216591031995 eyelet of channel; other site 216591031996 HMMPfam hit to PF00267, Gram-negative porin, score 3.3e-06 216591031997 Probable gene remnant. Similar to an internal region of Burkholderia cepacia (strain atcc 53795/ammd) betaine-aldehyde dehydrogenase UniProt:Q0B2K6 (EMBL:CP000442 (496 aa) fasta scores: E()=3.6e-05, 68.293% id in 41 aa 216591031998 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591031999 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 216591032000 conserved cys residue [active] 216591032001 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591032002 HMMPfam hit to PF01965, DJ-1/PfpI family, score 7e-06 216591032003 PS00041 Bacterial regulatory proteins, araC family signature. 216591032004 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 4.5e-06 216591032005 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591032006 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591032007 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591032008 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591032009 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032010 HMMPfam hit to PF01548, Transposase, score 2.9e-12 216591032011 Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566 216591032012 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591032013 active site 216591032014 phosphorylation site [posttranslational modification] 216591032015 intermolecular recognition site; other site 216591032016 dimerization interface [polypeptide binding]; other site 216591032017 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591032018 DNA binding residues [nucleotide binding] 216591032019 dimerization interface [polypeptide binding]; other site 216591032020 HMMPfam hit to PF00072, Response regulator receiver domain, score 3.2e-23 216591032021 HMMPfam hit to PF08281, Sigma-70, region, score 0.00041 216591032022 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 1.8e-19 216591032023 PS00622 Bacterial regulatory proteins, luxR family signature. 216591032024 PAS domain; Region: PAS_9; pfam13426 216591032025 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591032026 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591032027 ATP binding site [chemical binding]; other site 216591032028 Mg2+ binding site [ion binding]; other site 216591032029 G-X-G motif; other site 216591032030 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2.3e-34 216591032031 Domain of unknown function (DUF3331); Region: DUF3331; pfam11811 216591032032 Response regulator receiver domain; Region: Response_reg; pfam00072 216591032033 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591032034 active site 216591032035 phosphorylation site [posttranslational modification] 216591032036 intermolecular recognition site; other site 216591032037 dimerization interface [polypeptide binding]; other site 216591032038 HMMPfam hit to PF00072, Response regulator receiver domain, score 6.8e-21 216591032039 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591032040 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591032041 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 4.9e-14 216591032042 Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064 216591032043 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 216591032044 NAD(P) binding site [chemical binding]; other site 216591032045 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 5.4e-33 216591032046 PS00190 Cytochrome c family heme-binding site signature. 216591032047 PS00059 Zinc-containing alcohol dehydrogenases signature. 216591032048 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 8.9e-26 216591032049 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591032050 TAP-like protein; Region: Abhydrolase_4; pfam08386 216591032051 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 6.1e-22 216591032052 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591032053 Arginate lyase and other MDR family members; Region: AL_MDR; cd08252 216591032054 zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817 216591032055 putative NAD(P) binding site [chemical binding]; other site 216591032056 dimer interface [polypeptide binding]; other site 216591032057 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 1.9e-11 216591032058 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 5.7e-14 216591032059 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591032060 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591032061 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 4.7e-41 216591032062 mercuric reductase; Validated; Region: PRK06370 216591032063 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591032064 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 216591032065 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 3.4e-36 216591032066 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032067 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 1.5e-29 216591032068 HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 3.4e-25 216591032069 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 216591032070 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591032071 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 216591032072 Walker A/P-loop; other site 216591032073 ATP binding site [chemical binding]; other site 216591032074 Q-loop/lid; other site 216591032075 ABC transporter signature motif; other site 216591032076 Walker B; other site 216591032077 D-loop; other site 216591032078 H-loop/switch region; other site 216591032079 HMMPfam hit to PF00005, ABC transporter, score 1.7e-58 216591032080 PS00211 ABC transporters family signature. 216591032081 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032082 5 probable transmembrane helices predicted for BCAS0081 by TMHMM2.0 at aa 38-60, 80-99, 154-176, 186-208 and 269-291 216591032083 PS00539 Pyrokinins signature. 216591032084 Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695 216591032085 1 probable transmembrane helix predicted for BCAS0082 by TMHMM2.0 at aa 20-39 216591032086 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032087 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591032088 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591032089 Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977 216591032090 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.1e-19 216591032091 Predicted helix-turn-helix motif with score 1337.000, SD 3.74 at aa 32-53, sequence TSTAAICKAAGMSPGNLFHYFP 216591032092 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591032093 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591032094 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.3e-13 216591032095 Predicted helix-turn-helix motif with score 1613.000, SD 4.68 at aa 27-48, sequence FSYRDLSDLVGVKTSSIHYYFP 216591032096 peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561 216591032097 HMMPfam hit to PF02566, OsmC-like protein, score 1e-32 216591032098 Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312 216591032099 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 216591032100 substrate binding pocket [chemical binding]; other site 216591032101 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 216591032102 1 probable transmembrane helix predicted for BCAS0086 by TMHMM2.0 at aa 7-26 216591032103 HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 1.8e-96 216591032104 LrgA family; Region: LrgA; pfam03788 216591032105 HMMPfam hit to PF03788, LrgA family, score 2e-23 216591032106 3 probable transmembrane helices predicted for BCAS0087 by TMHMM2.0 at aa 20-42, 57-76 and 83-105 216591032107 Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346 216591032108 7 probable transmembrane helices predicted for BCAS0088 by TMHMM2.0 at aa 10-32, 44-63, 73-92, 105-127, 154-176, 189-208 and 218-240 216591032109 HMMPfam hit to PF04172, LrgB-like family, score 1.4e-112 216591032110 1 probable transmembrane helix predicted for BCAS0089 by TMHMM2.0 at aa 7-29 216591032111 NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767 216591032112 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591032113 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 1e-05 216591032114 HMMPfam hit to PF00258, Flavodoxin, score 3.9e-17 216591032115 Pirin-related protein [General function prediction only]; Region: COG1741 216591032116 Pirin; Region: Pirin; pfam02678 216591032117 HMMPfam hit to PF02678, Pirin, score 1e-64 216591032118 HMMPfam hit to PF07883, Cupin domain, score 0.0019 216591032119 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591032120 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591032121 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591032122 putative effector binding pocket; other site 216591032123 dimerization interface [polypeptide binding]; other site 216591032124 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.1e-11 216591032125 Predicted helix-turn-helix motif with score 1309.000, SD 3.65 at aa 19-40, sequence GSFTAAADQLMLSKQFVSRRTM 216591032126 HMMPfam hit to PF03466, LysR substrate binding domain, score 7.2e-54 216591032127 Fic family protein [Function unknown]; Region: COG3177 216591032128 Domain of unknown function (DUF4172); Region: DUF4172; pfam13776 216591032129 Fic/DOC family; Region: Fic; pfam02661 216591032130 HMMPfam hit to PF02661, Fic protein family, score 3.7e-20 216591032131 Protein of unknown function (DUF3311); Region: DUF3311; pfam11755 216591032132 2 probable transmembrane helices predicted for BCAS0094 by TMHMM2.0 at aa 2-24 and 34-56 216591032133 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032134 Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456 216591032135 Na binding site [ion binding]; other site 216591032136 13 probable transmembrane helices predicted for BCAS0095 by TMHMM2.0 at aa 4-18, 39-61, 71-90, 121-143, 153-175, 187-206, 226-248, 269-291, 311-333, 353-372, 376-398, 405-427 and 431-453 216591032137 HMMPfam hit to PF00474, Sodium:solute symporter family, score 4.8e-06 216591032138 Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574 216591032139 YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300 216591032140 active site 216591032141 HMMPfam hit to PF07969, Amidohydrolase family, score 1.4e-63 216591032142 putative GTP-binding protein YjiA; Provisional; Region: PRK11537 216591032143 CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492 216591032144 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833 216591032145 HMMPfam hit to PF02492, CobW/HypB/UreG, nucleotide-binding domain, score 6.1e-39 216591032146 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032147 HMMPfam hit to PF07683, Cobalamin synthesis protein cobW C-terminal, score 2.1e-06 216591032148 Protein of unknown function (DUF1311); Region: DUF1311; pfam07007 216591032149 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591032150 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591032151 DNA binding site [nucleotide binding] 216591032152 domain linker motif; other site 216591032153 This group includes the ligand-binding domain of putative DNA transcription repressors which are highly similar to that of the repressor specific for gluconate (GntR), a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR_like_1; cd06273 216591032154 putative dimerization interface [polypeptide binding]; other site 216591032155 putative ligand binding site [chemical binding]; other site 216591032156 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 2.7e-09 216591032157 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 1e-08 216591032158 Predicted helix-turn-helix motif with score 1651.000, SD 4.81 at aa 20-41, sequence SVLGDVAKLAGVSTATVSRVYN 216591032159 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 216591032160 Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174 216591032161 substrate binding site [chemical binding]; other site 216591032162 dimer interface [polypeptide binding]; other site 216591032163 ATP binding site [chemical binding]; other site 216591032164 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 2.6e-79 216591032165 PS00583 pfkB family of carbohydrate kinases signature 1. 216591032166 PS00584 pfkB family of carbohydrate kinases signature 2. 216591032167 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591032168 D-galactonate transporter; Region: 2A0114; TIGR00893 216591032169 putative substrate translocation pore; other site 216591032170 HMMPfam hit to PF00083, Sugar (and other) transporter, score 0.00018 216591032171 11 probable transmembrane helices predicted for BCAS0101 by TMHMM2.0 at aa 25-47, 62-84, 97-119, 151-173, 178-200, 246-268, 281-303, 318-336, 343-365, 375-397 and 404-426 216591032172 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.5e-70 216591032173 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032174 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032175 Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329 216591032176 Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408 216591032177 inhibitor site; inhibition site 216591032178 active site 216591032179 dimer interface [polypeptide binding]; other site 216591032180 catalytic residue [active] 216591032181 HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 7.9e-10 216591032182 Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195 216591032183 HMMPfam hit to PF07195, Flagellar hook-associated protein, score 4.2e-57 216591032184 HMMPfam hit to PF07196, Flagellin hook IN motif, score 3.6e-09 216591032185 HMMPfam hit to PF02465, Flagellar hook-associated protein, score 9.9e-13 216591032186 RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321 216591032187 dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254 216591032188 NADP binding site [chemical binding]; other site 216591032189 active site 216591032190 putative substrate binding site [chemical binding]; other site 216591032191 HMMPfam hit to PF04321, RmlD substrate binding domain, score 5.7e-43 216591032192 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.00058 216591032193 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 7.1e-09 216591032194 HMMPfam hit to PF07993, Male sterility protein, score 2.1e-05 216591032195 Domain of unknown function (DUF389); Region: DUF389; pfam04087 216591032196 7 probable transmembrane helices predicted for BCAS0106 by TMHMM2.0 at aa 43-65, 70-92, 105-127, 142-161, 168-190, 200-222 and 241-263 216591032197 HMMPfam hit to PF04087, Domain of unknown function (DUF389), score 5.4e-74 216591032198 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591032199 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591032200 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 216591032201 dimerization interface [polypeptide binding]; other site 216591032202 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.6e-15 216591032203 PS00063 Aldo/keto reductase family putative active site signature. 216591032204 PS00044 Bacterial regulatory proteins, lysR family signature. 216591032205 HMMPfam hit to PF03466, LysR substrate binding domain, score 5.2e-20 216591032206 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591032207 metabolite-proton symporter; Region: 2A0106; TIGR00883 216591032208 putative substrate translocation pore; other site 216591032209 HMMPfam hit to PF00083, Sugar (and other) transporter, score 1.8e-10 216591032210 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.9e-28 216591032211 12 probable transmembrane helices predicted for BCAS0108 by TMHMM2.0 at aa 27-49, 59-81, 90-112, 122-144, 165-184, 189-211, 242-259, 274-296, 309-328, 338-360, 373-395 and 405-422 216591032212 PS00216 Sugar transport proteins signature 1. 216591032213 PS00217 Sugar transport proteins signature 2. 216591032214 M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393 216591032215 active site 216591032216 Zn binding site [ion binding]; other site 216591032217 HMMPfam hit to PF04952, Succinylglutamate desuccinylase / Aspartoac, score 0.00017 216591032218 lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096 216591032219 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591032220 substrate binding pocket [chemical binding]; other site 216591032221 membrane-bound complex binding site; other site 216591032222 hinge residues; other site 216591032223 1 probable transmembrane helix predicted for BCAS0110 by TMHMM2.0 at aa 7-29 216591032224 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 7.6e-68 216591032225 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591032226 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591032227 dimer interface [polypeptide binding]; other site 216591032228 conserved gate region; other site 216591032229 putative PBP binding loops; other site 216591032230 ABC-ATPase subunit interface; other site 216591032231 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.2e-19 216591032232 4 probable transmembrane helices predicted for BCAS0111 by TMHMM2.0 at aa 20-42, 71-93, 98-117 and 200-222 216591032233 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591032234 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591032235 dimer interface [polypeptide binding]; other site 216591032236 conserved gate region; other site 216591032237 putative PBP binding loops; other site 216591032238 ABC-ATPase subunit interface; other site 216591032239 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.3e-11 216591032240 4 probable transmembrane helices predicted for BCAS0112 by TMHMM2.0 at aa 15-37, 57-79, 120-142 and 197-219 216591032241 ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; Region: HisP; COG4598 216591032242 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 216591032243 Walker A/P-loop; other site 216591032244 ATP binding site [chemical binding]; other site 216591032245 Q-loop/lid; other site 216591032246 ABC transporter signature motif; other site 216591032247 Walker B; other site 216591032248 D-loop; other site 216591032249 H-loop/switch region; other site 216591032250 HMMPfam hit to PF00005, ABC transporter, score 5.3e-64 216591032251 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032252 PS00211 ABC transporters family signature. 216591032253 Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332 216591032254 active sites [active] 216591032255 tetramer interface [polypeptide binding]; other site 216591032256 HMMPfam hit to PF00221, Phenylalanine and histidine ammonia-lyase, score 2.5e-94 216591032257 histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018 216591032258 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591032259 DNA-binding site [nucleotide binding]; DNA binding site 216591032260 The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866 216591032261 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 3.3e-23 216591032262 Predicted helix-turn-helix motif with score 1519.000, SD 4.36 at aa 51-72, sequence PTEAELVKEFGVARMTVSRALR 216591032263 HMMPfam hit to PF07702, UTRA domain, score 4.9e-30 216591032264 RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487 216591032265 Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078 216591032266 putative active site [active] 216591032267 putative NTP binding site [chemical binding]; other site 216591032268 putative nucleic acid binding site [nucleotide binding]; other site 216591032269 H-NS histone family; Region: Histone_HNS; pfam00816 216591032270 Domain in histone-like proteins of HNS family; Region: HNS; smart00528 216591032271 HMMPfam hit to PF00816, H-NS histone family, score 2.9e-08 216591032272 benzoate transport; Region: 2A0115; TIGR00895 216591032273 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591032274 putative substrate translocation pore; other site 216591032275 HMMPfam hit to PF00083, Sugar (and other) transporter, score 4.4e-08 216591032276 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.7e-46 216591032277 12 probable transmembrane helices predicted for BCAS0119 by TMHMM2.0 at aa 34-56, 66-85, 92-114, 118-140, 152-174, 178-197, 231-253, 268-287, 299-318, 323-345, 358-380 and 384-406 216591032278 PS00217 Sugar transport proteins signature 2. 216591032279 Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695 216591032280 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591032281 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591032282 trimer interface [polypeptide binding]; other site 216591032283 eyelet of channel; other site 216591032284 HMMPfam hit to PF00267, Gram-negative porin, score 0.00011 216591032285 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591032286 D-galactonate transporter; Region: 2A0114; TIGR00893 216591032287 putative substrate translocation pore; other site 216591032288 11 probable transmembrane helices predicted for BCAS0122 by TMHMM2.0 at aa 28-45, 66-88, 98-120, 158-180, 184-206, 254-276, 291-313, 325-347, 352-374, 387-409 and 415-437 216591032289 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.5e-61 216591032290 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 216591032291 Transcriptional regulator [Transcription]; Region: IclR; COG1414 216591032292 Bacterial transcriptional regulator; Region: IclR; pfam01614 216591032293 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 2.9e-14 216591032294 putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682 216591032295 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 216591032296 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 2.4e-09 216591032297 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 216591032298 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 216591032299 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 216591032300 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 2.1e-08 216591032301 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 1.6e-05 216591032302 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 4e-05 216591032303 Transcriptional regulators [Transcription]; Region: MarR; COG1846 216591032304 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591032305 dimerization interface [polypeptide binding]; other site 216591032306 putative Zn2+ binding site [ion binding]; other site 216591032307 putative DNA binding site [nucleotide binding]; other site 216591032308 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591032309 Coenzyme A binding pocket [chemical binding]; other site 216591032310 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.2e-14 216591032311 HMMPfam hit to PF01047, MarR family, score 3.3e-15 216591032312 ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125 216591032313 ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295 216591032314 Walker A/P-loop; other site 216591032315 ATP binding site [chemical binding]; other site 216591032316 Q-loop/lid; other site 216591032317 ABC transporter signature motif; other site 216591032318 Walker B; other site 216591032319 D-loop; other site 216591032320 H-loop/switch region; other site 216591032321 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582 216591032322 FOG: CBS domain [General function prediction only]; Region: COG0517 216591032323 HMMPfam hit to PF00571, CBS domain pair, score 1e-11 216591032324 HMMPfam hit to PF00005, ABC transporter, score 1.3e-59 216591032325 PS00211 ABC transporters family signature. 216591032326 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032327 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591032328 dimer interface [polypeptide binding]; other site 216591032329 conserved gate region; other site 216591032330 putative PBP binding loops; other site 216591032331 ABC-ATPase subunit interface; other site 216591032332 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.2e-20 216591032333 5 probable transmembrane helices predicted for BCAS0129 by TMHMM2.0 at aa 22-44, 51-73, 83-100, 150-172 and 176-198 216591032334 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591032335 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032336 ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891 216591032337 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732 216591032338 HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 4.7e-86 216591032339 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032340 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591032341 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591032342 dimer interface [polypeptide binding]; other site 216591032343 conserved gate region; other site 216591032344 putative PBP binding loops; other site 216591032345 ABC-ATPase subunit interface; other site 216591032346 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 8.4e-26 216591032347 5 probable transmembrane helices predicted for BCAS0131 by TMHMM2.0 at aa 7-26, 46-68, 89-111, 175-197 and 204-226 216591032348 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591032349 Agmatinase and related proteins; Region: Agmatinase_like_1; cd11589 216591032350 oligomer interface [polypeptide binding]; other site 216591032351 agmatinase; Region: agmatinase; TIGR01230 216591032352 active site 216591032353 Mn binding site [ion binding]; other site 216591032354 HMMPfam hit to PF00491, Arginase family, score 5.2e-13 216591032355 PS01053 Arginase family signature 3. 216591032356 PS00148 Arginase family signature 2. 216591032357 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591032358 D-galactonate transporter; Region: 2A0114; TIGR00893 216591032359 putative substrate translocation pore; other site 216591032360 10 probable transmembrane helices predicted for BCAS0133 by TMHMM2.0 at aa 12-29, 52-74, 81-103, 168-190, 232-254, 269-291, 303-325, 330-352, 365-387 and 397-419 216591032361 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032362 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.8e-68 216591032363 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032364 DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013 216591032365 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591032366 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591032367 dimerization interface [polypeptide binding]; other site 216591032368 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.1e-19 216591032369 Predicted helix-turn-helix motif with score 1809.000, SD 5.35 at aa 21-42, sequence RTLTAAARNLHISQPAVTKQLK 216591032370 PS00044 Bacterial regulatory proteins, lysR family signature. 216591032371 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.2e-17 216591032372 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 216591032373 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591032374 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591032375 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.8e-07 216591032376 Predicted helix-turn-helix motif with score 1455.000, SD 4.14 at aa 279-300, sequence KSMTALAGALHLTERTLRRRLD 216591032377 1 probable transmembrane helix predicted for BCAS0135 by TMHMM2.0 at aa 103-125 216591032378 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 216591032379 11 probable transmembrane helices predicted for BCAS0136 by TMHMM2.0 at aa 34-56, 66-83, 115-137, 147-169, 182-204, 214-236, 249-271, 299-321, 353-387, 402-424 and 431-453 216591032380 HMMPfam hit to PF00324, Amino acid permease, score 2.9e-16 216591032381 hypothetical protein; Provisional; Region: PRK06541 216591032382 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591032383 inhibitor-cofactor binding pocket; inhibition site 216591032384 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591032385 catalytic residue [active] 216591032386 HMMPfam hit to PF00202, Aminotransferase class-III, score 1.6e-108 216591032387 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591032388 Rhodococcus ruber 6-oxolauric acid dehydrogenase-like; Region: ALDH_CddD_SSP0762; cd07138 216591032389 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591032390 NAD binding site [chemical binding]; other site 216591032391 catalytic residues [active] 216591032392 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 6.5e-204 216591032393 PS00070 Aldehyde dehydrogenases cysteine active site. 216591032394 Transcriptional regulators [Transcription]; Region: FadR; COG2186 216591032395 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591032396 DNA-binding site [nucleotide binding]; DNA binding site 216591032397 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 216591032398 HMMPfam hit to PF07729, FCD domain, score 2.2e-18 216591032399 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 1.3e-15 216591032400 Periplasmic binding protein; Region: Peripla_BP_6; pfam13458 216591032401 Periplasmic solute-binding domain of active transport proteins that belong to the type I periplasmic binding fold protein family; Region: PBP1_SBP_like_1; cd06327 216591032402 putative ligand binding site [chemical binding]; other site 216591032403 PS00294 Prenyl group binding site (CAAX box). 216591032404 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 216591032405 TM-ABC transporter signature motif; other site 216591032406 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 4.5e-27 216591032407 7 probable transmembrane helices predicted for BCAS0141 by TMHMM2.0 at aa 10-32, 34-56, 61-83, 95-117, 137-159, 188-210 and 225-247 216591032408 ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177 216591032409 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 216591032410 TM-ABC transporter signature motif; other site 216591032411 8 probable transmembrane helices predicted for BCAS0142 by TMHMM2.0 at aa 30-49, 54-76, 99-121, 128-147, 178-197, 233-255, 270-292 and 299-318 216591032412 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 5.7e-39 216591032413 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032414 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 216591032415 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 216591032416 Walker A/P-loop; other site 216591032417 ATP binding site [chemical binding]; other site 216591032418 Q-loop/lid; other site 216591032419 ABC transporter signature motif; other site 216591032420 Walker B; other site 216591032421 D-loop; other site 216591032422 H-loop/switch region; other site 216591032423 HMMPfam hit to PF00005, ABC transporter, score 1e-41 216591032424 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032425 PS00211 ABC transporters family signature. 216591032426 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 216591032427 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 216591032428 Walker A/P-loop; other site 216591032429 ATP binding site [chemical binding]; other site 216591032430 Q-loop/lid; other site 216591032431 ABC transporter signature motif; other site 216591032432 Walker B; other site 216591032433 D-loop; other site 216591032434 H-loop/switch region; other site 216591032435 HMMPfam hit to PF00005, ABC transporter, score 2e-48 216591032436 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032437 PS00211 ABC transporters family signature. 216591032438 allantoate amidohydrolase; Reviewed; Region: PRK12893 216591032439 M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884 216591032440 active site 216591032441 metal binding site [ion binding]; metal-binding site 216591032442 dimer interface [polypeptide binding]; other site 216591032443 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 2.2e-40 216591032444 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 0.0035 216591032445 Uncharacterized conserved protein [Function unknown]; Region: COG5476 216591032446 Protein of unknown function (DUF1485); Region: DUF1485; pfam07364 216591032447 MlrC C-terminus; Region: MlrC_C; pfam07171 216591032448 HMMPfam hit to PF07364, Protein of unknown function (DUF1485), score 1.8e-31 216591032449 HMMPfam hit to PF07171, MlrC C-terminus, score 7.5e-35 216591032450 Uncharacterized conserved protein [Function unknown]; Region: COG3391 216591032451 1 probable transmembrane helix predicted for BCAS0147 by TMHMM2.0 at aa 13-35 216591032452 Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537 216591032453 Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971 216591032454 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032455 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032456 PS00141 Eukaryotic and viral aspartyl proteases active site. 216591032457 HMMPfam hit to PF07971, Glycosyl hydrolase family, score 3e-89 216591032458 PS00041 Bacterial regulatory proteins, araC family signature. 216591032459 PS00213 Lipocalin signature. 216591032460 1 probable transmembrane helix predicted for BCAS0150 by TMHMM2.0 at aa 13-35 216591032461 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591032462 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.9e-15 216591032463 Domain of unknown function (DUF4034); Region: DUF4034; pfam13226 216591032464 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 216591032465 HMMPfam hit to PF08238, Sel1 repeat, score 0.12 216591032466 HMMPfam hit to PF08238, Sel1 repeat, score 1.5 216591032467 Protein of unknown function (DUF1266); Region: DUF1266; pfam06889 216591032468 beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289 216591032469 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 216591032470 HMMPfam hit to PF00144, Beta-lactamase, score 6.4e-91 216591032471 PS00336 Beta-lactamase class-C active site. 216591032472 Ankyrin repeats (many copies); Region: Ank_5; pfam13857 216591032473 ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204 216591032474 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591032475 1 probable transmembrane helix predicted for BCAS0158 by TMHMM2.0 at aa 4-23 216591032476 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591032477 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 216591032478 active site 216591032479 catalytic tetrad [active] 216591032480 HMMPfam hit to PF00248, Aldo/keto reductase family, score 8e-16 216591032481 Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins; Region: PYR_PYL_RCAR_like; cd07821 216591032482 putative hydrophobic ligand binding site [chemical binding]; other site 216591032483 protein interface [polypeptide binding]; other site 216591032484 gate; other site 216591032485 DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986 216591032486 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591032487 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 216591032488 dimerization interface [polypeptide binding]; other site 216591032489 substrate binding pocket [chemical binding]; other site 216591032490 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.1e-44 216591032491 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.1e-22 216591032492 PS00044 Bacterial regulatory proteins, lysR family signature. 216591032493 Predicted helix-turn-helix motif with score 1412.000, SD 4.00 at aa 17-38, sequence EHVGRAAERLHISQSPLSRQIA 216591032494 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591032495 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591032496 substrate binding pocket [chemical binding]; other site 216591032497 membrane-bound complex binding site; other site 216591032498 hinge residues; other site 216591032499 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 8.1e-81 216591032500 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591032501 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 216591032502 HMMPfam hit to PF04324, BFD-like [2Fe-2S] binding domain, score 3.7e-18 216591032503 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 2e-08 216591032504 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510 216591032505 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032506 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591032507 hydroxyglutarate oxidase; Provisional; Region: PRK11728 216591032508 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2.4e-77 216591032509 1 probable transmembrane helix predicted for BCAS0165 by TMHMM2.0 at aa 7-24 216591032510 DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013 216591032511 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591032512 The C-terminal substrate-domain of LysR-type transcriptional regulators involved in the catabolism of opines and that of related regulators, contains the type 2 periplasmic binding fold; Region: PBP2_LysR_opines_like; cd08415 216591032513 putative dimerization interface [polypeptide binding]; other site 216591032514 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 8.2e-21 216591032515 Predicted helix-turn-helix motif with score 1743.000, SD 5.12 at aa 21-42, sequence HTVTRAARDLHISQPAVSRLIA 216591032516 PS00044 Bacterial regulatory proteins, lysR family signature. 216591032517 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.5e-46 216591032518 squalene-hopene cyclase; Region: hopene_cyclase; TIGR01507 216591032519 Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; Region: SQCY_1; cd02892 216591032520 Active site cavity [active] 216591032521 catalytic acid [active] 216591032522 HMMPfam hit to PF00432, Prenyltransferase and squalene oxidase re, score 3.2e-09 216591032523 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591032524 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591032525 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 7.9e-16 216591032526 Predicted helix-turn-helix motif with score 1596.000, SD 4.62 at aa 30-51, sequence LTLDAVAERAGVTKGALQYHFA 216591032527 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591032528 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591032529 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474 216591032530 putative effector binding pocket; other site 216591032531 putative dimerization interface [polypeptide binding]; other site 216591032532 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.9e-42 216591032533 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.2e-23 216591032534 PS00044 Bacterial regulatory proteins, lysR family signature. 216591032535 Predicted helix-turn-helix motif with score 1914.000, SD 5.71 at aa 17-38, sequence RNFTRAAAQLGVSQSALSRTVR 216591032536 Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917 216591032537 HMMPfam hit to PF07883, Cupin domain, score 1.2e-08 216591032538 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032539 Carboxymuconolactone decarboxylase family; Region: CMD; cl00460 216591032540 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599 216591032541 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032542 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 1.8e-21 216591032543 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 1.8e-25 216591032544 Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221 216591032545 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591032546 NAD(P) binding site [chemical binding]; other site 216591032547 active site 216591032548 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.1e-43 216591032549 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0027 216591032550 PS00061 Short-chain dehydrogenases/reductases family signature. 216591032551 4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235 216591032552 active site 1 [active] 216591032553 dimer interface [polypeptide binding]; other site 216591032554 hexamer interface [polypeptide binding]; other site 216591032555 active site 2 [active] 216591032556 HMMPfam hit to PF01361, Tautomerase enzyme, score 3.6e-11 216591032557 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591032558 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 0.00063 216591032559 PS00120 Lipases, serine active site. 216591032560 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591032561 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591032562 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591032563 dimerization interface [polypeptide binding]; other site 216591032564 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.9e-32 216591032565 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.2e-14 216591032566 PS00044 Bacterial regulatory proteins, lysR family signature. 216591032567 Predicted helix-turn-helix motif with score 1149.000, SD 3.10 at aa 21-42, sequence GSFARAADELARTEGAVSRQIG 216591032568 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 216591032569 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 1.4e-20 216591032570 Frameshift after codon 39 216591032571 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054 216591032572 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 216591032573 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 216591032574 dimer interface [polypeptide binding]; other site 216591032575 putative CheW interface [polypeptide binding]; other site 216591032576 2 probable transmembrane helices predicted for BCAS0181 by TMHMM2.0 at aa 15-37 and 185-207 216591032577 HMMPfam hit to PF00672, HAMP domain, score 7.3e-10 216591032578 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 2.2e-82 216591032579 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591032580 Protein of unknown function (DUF3224); Region: DUF3224; pfam11528 216591032581 Predicted helix-turn-helix motif with score 1058.000, SD 2.79 at aa 16-37, sequence ESLSRVAEPSGLGRMSLGKHFH 216591032582 Acetoacetate decarboxylase (ADC); Region: ADC; cl01919 216591032583 Uncharacterized conserved protein [Function unknown]; Region: COG3268 216591032584 HMMPfam hit to PF03435, Saccharopine dehydrogenase, score 4.9e-07 216591032585 1 probable transmembrane helix predicted for BCAS0184 by TMHMM2.0 at aa 286-305 216591032586 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591032587 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591032588 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591032589 dimerization interface [polypeptide binding]; other site 216591032590 HMMPfam hit to PF03466, LysR substrate binding domain, score 5.7e-28 216591032591 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.4e-17 216591032592 PS00044 Bacterial regulatory proteins, lysR family signature. 216591032593 Predicted helix-turn-helix motif with score 1403.000, SD 3.97 at aa 21-42, sequence RSFTGAGRRLNLSQSAVSAQIV 216591032594 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 216591032595 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591032596 HMMPfam hit to PF02525, Flavodoxin-like fold, score 2.7e-15 216591032597 LysE type translocator; Region: LysE; cl00565 216591032598 5 probable transmembrane helices predicted for BCAS0187 by TMHMM2.0 at aa 4-26, 38-57, 67-86, 150-172 and 182-204 216591032599 HMMPfam hit to PF01810, LysE type translocator, score 5e-26 216591032600 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591032601 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591032602 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591032603 dimerization interface [polypeptide binding]; other site 216591032604 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.4e-18 216591032605 Predicted helix-turn-helix motif with score 1465.000, SD 4.18 at aa 34-55, sequence ENFSRAADELYLTHGAVSRAVR 216591032606 PS00044 Bacterial regulatory proteins, lysR family signature. 216591032607 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.2e-14 216591032608 Cupin domain; Region: Cupin_2; pfam07883 216591032609 HMMPfam hit to PF07883, Cupin domain, score 0.00011 216591032610 H-NS histone family; Region: Histone_HNS; pfam00816 216591032611 Domain in histone-like proteins of HNS family; Region: HNS; smart00528 216591032612 HMMPfam hit to PF00816, H-NS histone family, score 3.1e-16 216591032613 This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199 216591032614 homotrimer interaction site [polypeptide binding]; other site 216591032615 putative active site [active] 216591032616 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 0.0017 216591032617 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 216591032618 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591032619 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591032620 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00014 216591032621 cinnamoyl-CoA reductase; Region: PLN02214 216591032622 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591032623 NAD(P) binding site [chemical binding]; other site 216591032624 active site 216591032625 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 7.5e-08 216591032626 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 4.5e-21 216591032627 HMMPfam hit to PF07993, Male sterility protein, score 4.6e-10 216591032628 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591032629 DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771 216591032630 dimerization interface [polypeptide binding]; other site 216591032631 DNA binding residues [nucleotide binding] 216591032632 Predicted helix-turn-helix motif with score 1409.000, SD 3.99 at aa 321-342, sequence HSPQECAALRGVSIGTVRAQIK 216591032633 Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434 216591032634 Probable polygalacturonase At3g15720; Region: PLN03003; cl14103 216591032635 HMMPfam hit to PF00295, Glycosyl hydrolases family, score 8.1e-09 216591032636 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032637 TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638 216591032638 Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480 216591032639 HMMPfam hit to PF03480, Bacterial extracellular solute-binding prot, score 3.7e-94 216591032640 TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090 216591032641 4 probable transmembrane helices predicted for BCAS0198 by TMHMM2.0 at aa 44-66, 76-98, 119-141 and 161-183 216591032642 HMMPfam hit to PF04290, Tripartite ATP-independent periplasmic trans, score 5.4e-22 216591032643 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032644 DctM-like transporters; Region: DctM; pfam06808 216591032645 TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593 216591032646 11 probable transmembrane helices predicted for BCAS0199 by TMHMM2.0 at aa 5-27, 42-64, 85-107, 184-206, 227-249, 254-276, 296-315, 330-349, 356-378, 388-410 and 417-439 216591032647 HMMPfam hit to PF06808, DctM-like transporters, score 5.4e-117 216591032648 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032649 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032650 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 216591032651 FAD binding domain; Region: FAD_binding_4; pfam01565 216591032652 HMMPfam hit to PF02913, FAD linked oxidases, C-terminal domain, score 1.2e-18 216591032653 HMMPfam hit to PF01565, FAD binding domain, score 8.6e-33 216591032654 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591032655 6 probable transmembrane helices predicted for BCAS0202 by TMHMM2.0 at aa 7-29, 39-56, 63-82, 97-119, 131-150 and 155-172 216591032656 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 216591032657 7 probable transmembrane helices predicted for BCAS0203 by TMHMM2.0 at aa 20-42, 160-182, 192-209, 216-238, 242-264, 269-291 and 329-351 216591032658 HMMPfam hit to PF01061, ABC-2 type transporter, score 0.00055 216591032659 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 216591032660 ABC-type thiamine transport system, ATPase component [Coenzyme metabolism]; Region: ThiQ; COG3840 216591032661 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591032662 Walker A/P-loop; other site 216591032663 ATP binding site [chemical binding]; other site 216591032664 Q-loop/lid; other site 216591032665 ABC transporter signature motif; other site 216591032666 Walker B; other site 216591032667 D-loop; other site 216591032668 H-loop/switch region; other site 216591032669 HMMPfam hit to PF00005, ABC transporter, score 2.3e-23 216591032670 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032671 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 216591032672 HMMPfam hit to PF02668, Taurine catabolism dioxygenase TauD, TfdA fa, score 1.1e-06 216591032673 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591032674 HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 7.1e-06 216591032675 HMMPfam hit to PF08241, Methyltransferase domain, score 3.4e-22 216591032676 HMMPfam hit to PF08242, Methyltransferase domain, score 2.3e-13 216591032677 Citrate synthase; Region: Citrate_synt; pfam00285 216591032678 Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416 216591032679 citrylCoA binding site [chemical binding]; other site 216591032680 oxalacetate binding site [chemical binding]; other site 216591032681 coenzyme A binding site [chemical binding]; other site 216591032682 catalytic triad [active] 216591032683 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591032684 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591032685 active site 216591032686 Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806 216591032687 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 6e-19 216591032688 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 5e-05 216591032689 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 7.1e-11 216591032690 acyl-CoA ligase (AMP-forming), exosortase A-associated; Region: ligase_PEP_1; TIGR03098 216591032691 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591032692 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 216591032693 acyl-activating enzyme (AAE) consensus motif; other site 216591032694 acyl-activating enzyme (AAE) consensus motif; other site 216591032695 AMP binding site [chemical binding]; other site 216591032696 active site 216591032697 CoA binding site [chemical binding]; other site 216591032698 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.8e-122 216591032699 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032700 PS00455 Putative AMP-binding domain signature. 216591032701 PS00141 Eukaryotic and viral aspartyl proteases active site. 216591032702 pyridoxal-dependent decarboxylase, exosortase A system-associated; Region: dCO2ase_PEP1; TIGR03099 216591032703 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Ornithine and Diaminopimelate Decarboxylases, and Related Enzymes; Region: PLPDE_III_ODC_DapDC_like; cd06810 216591032704 dimer interface [polypeptide binding]; other site 216591032705 active site 216591032706 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 216591032707 catalytic residues [active] 216591032708 substrate binding site [chemical binding]; other site 216591032709 HMMPfam hit to PF00278, Pyridoxal-dependent decarboxylase, C-, score 1.5e-12 216591032710 HMMPfam hit to PF02784, Pyridoxal-dependent decarboxylase, py, score 0.00027 216591032711 "initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827 216591032712 3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332 216591032713 dimer interface [polypeptide binding]; other site 216591032714 active site 216591032715 Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657 216591032716 dinuclear metal binding motif [ion binding]; other site 216591032717 Phosphopantetheine attachment site; Region: PKS_PP; smart00823 216591032718 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 4.3e-05 216591032719 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032720 ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591 216591032721 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 216591032722 FtsX-like permease family; Region: FtsX; pfam02687 216591032723 HMMPfam hit to PF02687, Predicted permease, score 7.7e-21 216591032724 4 probable transmembrane helices predicted for BCAS0220 by TMHMM2.0 at aa 19-41, 273-295, 322-344 and 372-394 216591032725 Predicted helix-turn-helix motif with score 976.000, SD 2.51 at aa 154-175, sequence VVGAELARKLGVHVGSVVQLMA 216591032726 Frameshift mutation after codon 26. Probably involved in production of an antifungal agent 216591032727 HMMPfam hit to PF00005, ABC transporter, score 1.3e-50 216591032728 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318 216591032729 Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931 216591032730 acyl-activating enzyme (AAE) consensus motif; other site 216591032731 active site 216591032732 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.1e-76 216591032733 PS00455 Putative AMP-binding domain signature. 216591032734 Fatty acid desaturase; Region: FA_desaturase; pfam00487 216591032735 The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cd01060 216591032736 putative di-iron ligands [ion binding]; other site 216591032737 The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615 216591032738 3 probable transmembrane helices predicted for BCAS0223 by TMHMM2.0 at aa 42-64, 84-103 and 181-203 216591032739 HMMPfam hit to PF00487, Fatty acid desaturase, score 2.8e-32 216591032740 Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264 216591032741 dinuclear metal binding motif [ion binding]; other site 216591032742 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591032743 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591032744 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591032745 dimerization interface [polypeptide binding]; other site 216591032746 substrate binding pocket [chemical binding]; other site 216591032747 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.3e-15 216591032748 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591032749 Predicted helix-turn-helix motif with score 2000.000, SD 6.00 at aa 20-41, sequence LSFTRAGQELNVTQSAVSRQVK 216591032750 PS00044 Bacterial regulatory proteins, lysR family signature. 216591032751 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.3e-30 216591032752 3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427 216591032753 homoserine O-acetyltransferase; Provisional; Region: metX; cl17114 216591032754 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.7e-20 216591032755 proline/glycine betaine transporter; Provisional; Region: PRK10642 216591032756 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591032757 putative substrate translocation pore; other site 216591032758 HMMPfam hit to PF00083, Sugar (and other) transporter, score 4.9e-39 216591032759 12 probable transmembrane helices predicted for BCAS0227 by TMHMM2.0 at aa 34-56, 71-93, 106-128, 138-160, 173-195, 205-227, 264-286, 301-323, 330-352, 362-384, 391-413 and 423-442 216591032760 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4e-30 216591032761 PS00216 Sugar transport proteins signature 1. 216591032762 PS00217 Sugar transport proteins signature 2. 216591032763 Topoisomerase IB [DNA replication, recombination, and repair]; Region: COG3569 216591032764 DNA topoisomerase IB, C-terminal catalytic domain. Topoisomerase I promotes the relaxation of both positive and negative DNA superhelical tension by introducing a transient single-stranded break in duplex DNA. This function is vital for the processes of...; Region: Topo_IB_C; cd00659 216591032765 active site 216591032766 DNA binding site [nucleotide binding] 216591032767 Int/Topo IB signature motif; other site 216591032768 catalytic residues [active] 216591032769 Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309 216591032770 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 216591032771 putative ligand binding site [chemical binding]; other site 216591032772 1 probable transmembrane helix predicted for BCAS0229 by TMHMM2.0 at aa 7-26 216591032773 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 0.00086 216591032774 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 216591032775 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 216591032776 Walker A/P-loop; other site 216591032777 ATP binding site [chemical binding]; other site 216591032778 Q-loop/lid; other site 216591032779 ABC transporter signature motif; other site 216591032780 Walker B; other site 216591032781 D-loop; other site 216591032782 H-loop/switch region; other site 216591032783 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 216591032784 HMMPfam hit to PF00005, ABC transporter, score 7.3e-52 216591032785 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032786 HMMPfam hit to PF00005, ABC transporter, score 2.2e-25 216591032787 PS00211 ABC transporters family signature. 216591032788 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591032789 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591032790 TM-ABC transporter signature motif; other site 216591032791 8 probable transmembrane helices predicted for BCAS0231 by TMHMM2.0 at aa 12-34, 49-68, 75-92, 102-124, 129-151, 166-188, 215-237 and 257-279 216591032792 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 3.4e-49 216591032793 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591032794 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591032795 TM-ABC transporter signature motif; other site 216591032796 9 probable transmembrane helices predicted for BCAS0232 by TMHMM2.0 at aa 15-37, 42-64, 69-88, 95-117, 122-144, 165-187, 218-240, 260-282 and 297-314 216591032797 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.8e-53 216591032798 7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696 216591032799 7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695 216591032800 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591032801 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591032802 dimer interface [polypeptide binding]; other site 216591032803 phosphorylation site [posttranslational modification] 216591032804 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591032805 ATP binding site [chemical binding]; other site 216591032806 Mg2+ binding site [ion binding]; other site 216591032807 G-X-G motif; other site 216591032808 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2.3e-29 216591032809 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.1e-13 216591032810 7 probable transmembrane helices predicted for BCAS0234 by TMHMM2.0 at aa 176-198, 203-225, 240-259, 271-293, 298-320, 327-344 and 364-386 216591032811 Response regulator receiver domain; Region: Response_reg; pfam00072 216591032812 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591032813 active site 216591032814 phosphorylation site [posttranslational modification] 216591032815 intermolecular recognition site; other site 216591032816 dimerization interface [polypeptide binding]; other site 216591032817 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591032818 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591032819 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 2.1e-12 216591032820 PS00041 Bacterial regulatory proteins, araC family signature. 216591032821 Predicted helix-turn-helix motif with score 1496.000, SD 4.28 at aa 176-197, sequence PALEELARQVGTHEKRLSRVFR 216591032822 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.5e-35 216591032823 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 216591032824 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591032825 trimer interface [polypeptide binding]; other site 216591032826 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591032827 trimer interface [polypeptide binding]; other site 216591032828 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 216591032829 trimer interface [polypeptide binding]; other site 216591032830 YadA-like C-terminal region; Region: YadA; pfam03895 216591032831 HMMPfam hit to PF05658, Hep_Hag, score 0.0022 216591032832 HMMPfam hit to PF05658, Hep_Hag, score 7.1e-06 216591032833 HMMPfam hit to PF05658, Hep_Hag, score 0.45 216591032834 HMMPfam hit to PF05658, Hep_Hag, score 0.012 216591032835 HMMPfam hit to PF05658, Hep_Hag, score 0.0019 216591032836 HMMPfam hit to PF05658, Hep_Hag, score 0.0017 216591032837 HMMPfam hit to PF05658, Hep_Hag, score 0.0009 216591032838 HMMPfam hit to PF05658, Hep_Hag, score 0.00012 216591032839 HMMPfam hit to PF05658, Hep_Hag, score 6.8e-06 216591032840 HMMPfam hit to PF05658, Hep_Hag, score 0.00041 216591032841 PS00012 Phosphopantetheine attachment site. 216591032842 HMMPfam hit to PF05658, Hep_Hag, score 0.028 216591032843 HMMPfam hit to PF05658, Hep_Hag, score 0.00075 216591032844 HMMPfam hit to PF05658, Hep_Hag, score 1 216591032845 HMMPfam hit to PF05662, Haemagglutinin, score 1.4e-07 216591032846 HMMPfam hit to PF05658, Hep_Hag, score 1.6e-05 216591032847 HMMPfam hit to PF05662, Haemagglutinin, score 7.2e-06 216591032848 HMMPfam hit to PF05658, Hep_Hag, score 0.00098 216591032849 HMMPfam hit to PF05658, Hep_Hag, score 0.089 216591032850 HMMPfam hit to PF05658, Hep_Hag, score 0.0022 216591032851 HMMPfam hit to PF05658, Hep_Hag, score 0.00073 216591032852 HMMPfam hit to PF05662, Haemagglutinin, score 2.6e-06 216591032853 HMMPfam hit to PF05658, Hep_Hag, score 0.016 216591032854 HMMPfam hit to PF05658, Hep_Hag, score 7.1e-07 216591032855 HMMPfam hit to PF05662, Haemagglutinin, score 4.5e-06 216591032856 HMMPfam hit to PF03895, YadA-like C-terminal region, score 9.3e-07 216591032857 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 216591032858 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 216591032859 ligand binding site [chemical binding]; other site 216591032860 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032861 HMMPfam hit to PF00691, OmpA family, score 3.9e-31 216591032862 Protein of unknown function (DUF3820); Region: DUF3820; pfam12843 216591032863 Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178 216591032864 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 216591032865 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 216591032866 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591032867 Walker A/P-loop; other site 216591032868 ATP binding site [chemical binding]; other site 216591032869 Q-loop/lid; other site 216591032870 ABC transporter signature motif; other site 216591032871 Walker B; other site 216591032872 D-loop; other site 216591032873 H-loop/switch region; other site 216591032874 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 216591032875 Walker A/P-loop; other site 216591032876 ATP binding site [chemical binding]; other site 216591032877 Q-loop/lid; other site 216591032878 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 216591032879 ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271 216591032880 HMMPfam hit to PF00005, ABC transporter, score 2.4e-08 216591032881 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032882 HMMPfam hit to PF00005, ABC transporter, score 5.7e-14 216591032883 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032884 PS00211 ABC transporters family signature. 216591032885 HMMPfam hit to PF00005, ABC transporter, score 1.1e-09 216591032886 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032887 PS00211 ABC transporters family signature. 216591032888 HMMPfam hit to PF00005, ABC transporter, score 1.9e-18 216591032889 PS00017 ATP/GTP-binding site motif A (P-loop). 216591032890 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032891 PS00190 Cytochrome c family heme-binding site signature. 216591032892 PS00211 ABC transporters family signature. 216591032893 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591032894 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591032895 substrate binding pocket [chemical binding]; other site 216591032896 membrane-bound complex binding site; other site 216591032897 hinge residues; other site 216591032898 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 3.1e-45 216591032899 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 216591032900 Sodium:dicarboxylate symporter family; Region: SDF; cl00573 216591032901 HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 9.4e-103 216591032902 8 probable transmembrane helices predicted for BCAS0241 by TMHMM2.0 at aa 7-29, 56-78, 85-107, 154-171, 192-214, 234-256, 318-340 and 355-377 216591032903 Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062 216591032904 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591032905 substrate binding pocket [chemical binding]; other site 216591032906 membrane-bound complex binding site; other site 216591032907 hinge residues; other site 216591032908 30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270 216591032909 HMMPfam hit to PF01165, Ribosomal protein S21, score 2.2e-23 216591032910 Chromate resistance exported protein; Region: Chrome_Resist; pfam09828 216591032911 Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059 216591032912 chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937 216591032913 Chromate transporter; Region: Chromate_transp; pfam02417 216591032914 HMMPfam hit to PF02417, Chromate transporter, score 2.6e-77 216591032915 12 probable transmembrane helices predicted for BCAS0249 by TMHMM2.0 at aa 15-37, 56-78, 82-104, 111-133, 148-180, 193-211, 226-248, 261-283, 288-310, 319-341, 346-365 and 372-389 216591032916 HMMPfam hit to PF02417, Chromate transporter, score 9.3e-12 216591032917 Uncharacterized conserved protein [Function unknown]; Region: COG4275 216591032918 Domain of unknown function (DUF4382); Region: DUF4382; pfam14321 216591032919 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032920 DJ-1 family protein; Region: not_thiJ; TIGR01383 216591032921 Putative amidotransferase; Region: DUF4066; pfam13278 216591032922 conserved cys residue [active] 216591032923 HMMPfam hit to PF01965, DJ-1/PfpI family, score 0.0033 216591032924 2-dehydropantoate 2-reductase; Provisional; Region: PRK12921 216591032925 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 216591032926 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 216591032927 HMMPfam hit to PF08546, Ketopantoate reductase PanE/ApbA C terminal, score 1e-14 216591032928 HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 2.9e-35 216591032929 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591032930 Major Facilitator Superfamily; Region: MFS_1; pfam07690 216591032931 putative substrate translocation pore; other site 216591032932 10 probable transmembrane helices predicted for BCAS0254 by TMHMM2.0 at aa 21-43, 53-75, 95-117, 175-197, 218-240, 255-277, 284-306, 311-333, 346-368 and 372-394 216591032933 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.2e-29 216591032934 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032935 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591032936 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591032937 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591032938 dimerization interface [polypeptide binding]; other site 216591032939 substrate binding pocket [chemical binding]; other site 216591032940 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.8e-20 216591032941 Predicted helix-turn-helix motif with score 1216.000, SD 3.33 at aa 30-51, sequence GSFAGAAAELHVTHWAVGKQIR 216591032942 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.5e-42 216591032943 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591032944 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591032945 eyelet of channel; other site 216591032946 trimer interface [polypeptide binding]; other site 216591032947 HMMPfam hit to PF00267, Gram-negative porin, score 0.00012 216591032948 1 probable transmembrane helix predicted for BCAS0256 by TMHMM2.0 at aa 7-29 216591032949 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591032950 Coenzyme A binding pocket [chemical binding]; other site 216591032951 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.7e-10 216591032952 phosphonate utilization associated transcriptional regulator; Region: phnR_burk; TIGR03338 216591032953 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591032954 DNA-binding site [nucleotide binding]; DNA binding site 216591032955 FCD domain; Region: FCD; pfam07729 216591032956 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.7e-17 216591032957 HMMPfam hit to PF07729, FCD domain, score 1.9e-13 216591032958 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 216591032959 Sodium:dicarboxylate symporter family; Region: SDF; pfam00375 216591032960 HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 4.4e-63 216591032961 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591032962 9 probable transmembrane helices predicted for BCAS0259 by TMHMM2.0 at aa 15-37, 42-64, 79-101, 137-159, 184-206, 218-240, 278-295, 316-335 and 345-367 216591032963 RNase II stability modulator; Provisional; Region: PRK10060 216591032964 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 216591032965 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591032966 Coenzyme A binding pocket [chemical binding]; other site 216591032967 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.2e-10 216591032968 Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms]; Region: COG3437 216591032969 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591032970 active site 216591032971 phosphorylation site [posttranslational modification] 216591032972 intermolecular recognition site; other site 216591032973 dimerization interface [polypeptide binding]; other site 216591032974 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 216591032975 Zn2+ binding site [ion binding]; other site 216591032976 Mg2+ binding site [ion binding]; other site 216591032977 HMMPfam hit to PF00072, Response regulator receiver domain, score 6.5e-33 216591032978 HMMPfam hit to PF01966, HD domain, score 4.3e-08 216591032979 MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300 216591032980 Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707 216591032981 Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707 216591032982 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591032983 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591032984 dimer interface [polypeptide binding]; other site 216591032985 phosphorylation site [posttranslational modification] 216591032986 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591032987 ATP binding site [chemical binding]; other site 216591032988 Mg2+ binding site [ion binding]; other site 216591032989 G-X-G motif; other site 216591032990 7 probable transmembrane helices predicted for BCAS0264 by TMHMM2.0 at aa 10-31, 43-65, 75-97, 109-131, 141-163, 176-198 and 213-235 216591032991 HMMPfam hit to PF03707, Bacterial signalling protein N terminal rep, score 3.9e-19 216591032992 HMMPfam hit to PF03707, Bacterial signalling protein N terminal rep, score 4.5e-16 216591032993 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.1e-08 216591032994 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.9e-40 216591032995 Esterase PHB depolymerase; Region: Esterase_phd; pfam10503 216591032996 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591032997 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591032998 dimer interface [polypeptide binding]; other site 216591032999 phosphorylation site [posttranslational modification] 216591033000 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591033001 ATP binding site [chemical binding]; other site 216591033002 Mg2+ binding site [ion binding]; other site 216591033003 G-X-G motif; other site 216591033004 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 7.6e-13 216591033005 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.9e-29 216591033006 Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402 216591033007 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 216591033008 active site 216591033009 metal binding site [ion binding]; metal-binding site 216591033010 hexamer interface [polypeptide binding]; other site 216591033011 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 8.1e-20 216591033012 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591033013 substrate binding pocket [chemical binding]; other site 216591033014 membrane-bound complex binding site; other site 216591033015 urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424 216591033016 urea carboxylase-associated protein 2; Region: urea_degr_2; TIGR03425 216591033017 urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424 216591033018 Domain of unknown function (DUF1989); Region: DUF1989; pfam09347 216591033019 urea carboxylase; Region: urea_carbox; TIGR02712 216591033020 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 216591033021 ATP-grasp domain; Region: ATP-grasp_4; cl17255 216591033022 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 216591033023 Allophanate hydrolase subunit 2; Region: AHS2; smart00797 216591033024 Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896 216591033025 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 216591033026 carboxyltransferase (CT) interaction site; other site 216591033027 biotinylation site [posttranslational modification]; other site 216591033028 HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 1.3e-43 216591033029 HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 3.8e-72 216591033030 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 216591033031 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 216591033032 HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain, score 6.1e-44 216591033033 HMMPfam hit to PF02626, Allophanate hydrolase subunit, score 6e-88 216591033034 HMMPfam hit to PF02682, Allophanate hydrolase subunit, score 0.0032 216591033035 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 2.7e-11 216591033036 allophanate hydrolase; Provisional; Region: PRK08186 216591033037 Amidase; Region: Amidase; cl11426 216591033038 HMMPfam hit to PF01425, Amidase, score 9.4e-80 216591033039 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033040 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591033041 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591033042 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591033043 dimer interface [polypeptide binding]; other site 216591033044 conserved gate region; other site 216591033045 putative PBP binding loops; other site 216591033046 ABC-ATPase subunit interface; other site 216591033047 6 probable transmembrane helices predicted for BCAS0274 by TMHMM2.0 at aa 25-47, 134-156, 169-189, 194-211, 253-275 and 290-312 216591033048 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.2e-15 216591033049 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 216591033050 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 216591033051 Walker A/P-loop; other site 216591033052 ATP binding site [chemical binding]; other site 216591033053 Q-loop/lid; other site 216591033054 ABC transporter signature motif; other site 216591033055 Walker B; other site 216591033056 D-loop; other site 216591033057 H-loop/switch region; other site 216591033058 HMMPfam hit to PF00005, ABC transporter, score 3e-59 216591033059 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033060 PS00211 ABC transporters family signature. 216591033061 Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062 216591033062 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591033063 substrate binding pocket [chemical binding]; other site 216591033064 membrane-bound complex binding site; other site 216591033065 hinge residues; other site 216591033066 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591033067 Uncharacterized Saccharopolyspora spinosa aldehyde dehydrogenase (AAS00426)-like; Region: ALDH_AAS00426; cd07109 216591033068 NAD(P) binding site [chemical binding]; other site 216591033069 catalytic residues [active] 216591033070 catalytic residues [active] 216591033071 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.4e-203 216591033072 PS00070 Aldehyde dehydrogenases cysteine active site. 216591033073 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591033074 Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473 216591033075 tartrate dehydrogenase; Region: TTC; TIGR02089 216591033076 HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase, score 3.4e-97 216591033077 PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 216591033078 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591033079 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591033080 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591033081 dimerization interface [polypeptide binding]; other site 216591033082 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.6e-35 216591033083 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3e-15 216591033084 PS00044 Bacterial regulatory proteins, lysR family signature. 216591033085 Predicted helix-turn-helix motif with score 1512.000, SD 4.34 at aa 17-38, sequence GSLSRAAQQSHMSLSTASRRIA 216591033086 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591033087 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591033088 putative substrate translocation pore; other site 216591033089 12 probable transmembrane helices predicted for BCAS0280 by TMHMM2.0 at aa 31-48, 63-85, 101-120, 125-147, 159-181, 196-213, 257-279, 294-313, 325-344, 348-370, 377-399 and 414-436 216591033090 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.1e-51 216591033091 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033092 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 216591033093 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084 216591033094 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 2.8e-54 216591033095 DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986 216591033096 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591033097 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 216591033098 dimerization interface [polypeptide binding]; other site 216591033099 substrate binding pocket [chemical binding]; other site 216591033100 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.5e-33 216591033101 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2e-19 216591033102 PS00044 Bacterial regulatory proteins, lysR family signature. 216591033103 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591033104 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591033105 putative substrate translocation pore; other site 216591033106 12 probable transmembrane helices predicted for BCAS0284 by TMHMM2.0 at aa 7-28, 43-65, 72-91, 101-123, 130-149, 164-186, 206-228, 243-265, 272-289, 294-316, 329-351 and 356-378 216591033107 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.7e-36 216591033108 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033109 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033110 ATP-grasp domain; Region: ATP-grasp_4; pfam13535 216591033111 HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase, ATP, score 0.00036 216591033112 HMMPfam hit to PF02655, ATP-grasp domain, score 0.00048 216591033113 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 216591033114 9 probable transmembrane helices predicted for BCAS0286 by TMHMM2.0 at aa 7-26, 30-52, 64-86, 96-118, 123-145, 160-182, 195-217, 222-244 and 264-286 216591033115 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033116 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033117 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591033118 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591033119 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591033120 dimerization interface [polypeptide binding]; other site 216591033121 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.6e-18 216591033122 Predicted helix-turn-helix motif with score 1116.000, SD 2.99 at aa 16-37, sequence GSALRAAERLGCTQSNVTARLR 216591033123 PS00044 Bacterial regulatory proteins, lysR family signature. 216591033124 HMMPfam hit to PF03466, LysR substrate binding domain, score 5.7e-31 216591033125 1 probable transmembrane helix predicted for BCAS0287 by TMHMM2.0 at aa 211-233 216591033126 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033127 hypothetical protein; Provisional; Region: PRK07206 216591033128 ATP-grasp domain; Region: ATP-grasp_4; pfam13535 216591033129 HMMPfam hit to PF02655, ATP-grasp domain, score 0.0007 216591033130 HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase, ATP, score 0.0018 216591033131 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591033132 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591033133 putative substrate translocation pore; other site 216591033134 14 probable transmembrane helices predicted for BCAS0289 by TMHMM2.0 at aa 28-50, 65-87, 99-121, 125-147, 159-181, 186-205, 225-244, 249-268, 289-308, 318-340, 347-369, 384-406, 426-448 and 452-469 216591033135 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.1e-48 216591033136 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033137 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 216591033138 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591033139 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591033140 substrate binding pocket [chemical binding]; other site 216591033141 membrane-bound complex binding site; other site 216591033142 hinge residues; other site 216591033143 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.4e-29 216591033144 Inclusion body protein; Region: PixA; pfam12306 216591033145 Inclusion body protein; Region: PixA; pfam12306 216591033146 Predicted membrane protein [Function unknown]; Region: COG2246 216591033147 GtrA-like protein; Region: GtrA; pfam04138 216591033148 HMMPfam hit to PF04138, GtrA-like protein, score 2.6e-06 216591033149 4 probable transmembrane helices predicted for BCAS0294 by TMHMM2.0 at aa 12-34, 44-66, 73-92 and 102-124 216591033150 Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187 216591033151 Ligand binding site; other site 216591033152 Putative Catalytic site; other site 216591033153 DXD motif; other site 216591033154 2 probable transmembrane helices predicted for BCAS0295 by TMHMM2.0 at aa 240-262 and 272-294 216591033155 HMMPfam hit to PF00535, Glycosyl transferase family, score 4.9e-27 216591033156 Protein of unknown function (DUF2029); Region: DUF2029; pfam09594 216591033157 8 probable transmembrane helices predicted for BCAS0296 by TMHMM2.0 at aa 39-61, 129-151, 163-185, 205-227, 234-256, 296-318, 325-343 and 386-408 216591033158 Protein of unknown function (DUF2029); Region: DUF2029; pfam09594 216591033159 8 probable transmembrane helices predicted for BCAS0297 by TMHMM2.0 at aa 24-46, 114-136, 157-179, 199-221, 228-250, 284-306, 319-336 and 385-402 216591033160 HMMPfam hit to PF04964, Flp/Fap pilin component, score 2.5e-18 216591033161 1 probable transmembrane helix predicted for BCAS0298 by TMHMM2.0 at aa 21-43 216591033162 Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion]; Region: Flp; COG3847 216591033163 HMMPfam hit to PF04964, Flp/Fap pilin component, score 2.1e-20 216591033164 1 probable transmembrane helix predicted for BCAS0299 by TMHMM2.0 at aa 20-42 216591033165 Flp/Fap pilin component; Region: Flp_Fap; pfam04964 216591033166 HMMPfam hit to PF04964, Flp/Fap pilin component, score 3e-09 216591033167 2 probable transmembrane helices predicted for BCAS0300 by TMHMM2.0 at aa 20-39 and 49-71 216591033168 Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960 216591033169 5 probable transmembrane helices predicted for BCAS0301 by TMHMM2.0 at aa 4-23, 35-53, 57-79, 99-121 and 154-176 216591033170 HMMPfam hit to PF01478, Type IV leader peptidase family, score 1.5e-17 216591033171 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033172 Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190 216591033173 active site 216591033174 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033175 Flp pilus assembly protein CpaB [Intracellular trafficking and secretion]; Region: CpaB; COG3745 216591033176 SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614 216591033177 1 probable transmembrane helix predicted for BCAS0303 by TMHMM2.0 at aa 7-29 216591033178 HMMPfam hit to PF06981, Flp pilus assembly protein CpaB, score 5.7e-56 216591033179 Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629 216591033180 Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion]; Region: CpaC; COG4964 216591033181 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 216591033182 1 probable transmembrane helix predicted for BCAS0304 by TMHMM2.0 at aa 17-39 216591033183 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 5.5e-08 216591033184 HMMPfam hit to PF00263, Bacterial type II and III secretion system p, score 5.3e-65 216591033185 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033186 Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961 216591033187 Putative Flp pilus-assembly TadE/G-like; Region: Tad; pfam13400 216591033188 1 probable transmembrane helix predicted for BCAS0306 by TMHMM2.0 at aa 21-43 216591033189 Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961 216591033190 TadE-like protein; Region: TadE; pfam07811 216591033191 HMMPfam hit to PF07811, TadE-like protein, score 1.2e-14 216591033192 1 probable transmembrane helix predicted for BCAS0307 by TMHMM2.0 at aa 13-35 216591033193 Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961 216591033194 TadE-like protein; Region: TadE; pfam07811 216591033195 HMMPfam hit to PF07811, TadE-like protein, score 7e-13 216591033196 1 probable transmembrane helix predicted for BCAS0308 by TMHMM2.0 at aa 17-39 216591033197 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033198 Flp pilus assembly protein, ATPase CpaE [Intracellular trafficking and secretion]; Region: CpaE; COG4963 216591033199 This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111 216591033200 This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111 216591033201 PS00237 G-protein coupled receptors signature. 216591033202 Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962 216591033203 Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130 216591033204 ATP binding site [chemical binding]; other site 216591033205 Walker A motif; other site 216591033206 hexamer interface [polypeptide binding]; other site 216591033207 Walker B motif; other site 216591033208 HMMPfam hit to PF00437, Type II/IV secretion system protein, score 1.3e-116 216591033209 PS00227 Tubulin subunits alpha, beta, and gamma signature. 216591033210 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033211 Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965 216591033212 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 216591033213 5 probable transmembrane helices predicted for BCAS0311 by TMHMM2.0 at aa 5-27, 94-116, 121-140, 266-285 and 300-317 216591033214 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 2.2e-15 216591033215 Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064 216591033216 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 216591033217 4 probable transmembrane helices predicted for BCAS0312 by TMHMM2.0 at aa 10-32, 104-126, 136-158 and 287-309 216591033218 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 9.2e-19 216591033219 Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768 216591033220 Flavin reductase like domain; Region: Flavin_Reduct; smart00903 216591033221 HMMPfam hit to PF01613, Flavin reductase like domain, score 1.5e-47 216591033222 NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232 216591033223 short chain dehydrogenase; Provisional; Region: PRK08265 216591033224 classical (c) SDRs; Region: SDR_c; cd05233 216591033225 NAD(P) binding site [chemical binding]; other site 216591033226 active site 216591033227 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0025 216591033228 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.3e-20 216591033229 PS00061 Short-chain dehydrogenases/reductases family signature. 216591033230 Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412 216591033231 BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840 216591033232 SnoaL-like domain; Region: SnoaL_2; pfam12680 216591033233 HMMPfam hit to PF07366, SnoaL-like polyketide cyclase, score 0.00083 216591033234 HMMPfam hit to PF01738, Dienelactone hydrolase family, score 1.4e-57 216591033235 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591033236 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591033237 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00081 216591033238 Predicted helix-turn-helix motif with score 1883.000, SD 5.60 at aa 248-269, sequence LTIERLADLAGVSPSTLFAGFR 216591033239 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.6e-05 216591033240 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 216591033241 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 216591033242 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591033243 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 216591033244 4-hydroxybenzoyl-CoA reductase, gamma subunit; Region: 4hydroxCoAred; TIGR03193 216591033245 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591033246 catalytic loop [active] 216591033247 iron binding site [ion binding]; other site 216591033248 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 216591033249 HMMPfam hit to PF01799, [2Fe-2S] binding domain, score 3.5e-28 216591033250 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 2.7e-08 216591033251 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591033252 Autotransporter beta-domain; Region: Autotransporter; pfam03797 216591033253 1 probable transmembrane helix predicted for BCAS0321 by TMHMM2.0 at aa 21-43 216591033254 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033255 HMMPfam hit to PF05594, Haemagluttinin repeat, score 2 216591033256 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 99 216591033257 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 27 216591033258 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 79 216591033259 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 32 216591033260 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 50 216591033261 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 56 216591033262 HMMPfam hit to PF02415, Chlamydia polymorphic membrane protei, score 28 216591033263 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 22 216591033264 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 50 216591033265 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 65 216591033266 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 65 216591033267 PS00583 pfkB family of carbohydrate kinases signature 1. 216591033268 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 65 216591033269 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 64 216591033270 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033271 HMMPfam hit to PF03797, Autotransporter beta-domain, score 1.1e-39 216591033272 PS00190 Cytochrome c family heme-binding site signature. 216591033273 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591033274 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591033275 DNA binding site [nucleotide binding] 216591033276 domain linker motif; other site 216591033277 Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267 216591033278 dimerization interface [polypeptide binding]; other site 216591033279 ligand binding site [chemical binding]; other site 216591033280 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 1e-07 216591033281 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 2.5e-06 216591033282 Predicted helix-turn-helix motif with score 1976.000, SD 5.92 at aa 2-23, sequence VTLAQVAQRANVTAATVSNVLR 216591033283 maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000 216591033284 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 216591033285 Walker A/P-loop; other site 216591033286 ATP binding site [chemical binding]; other site 216591033287 Q-loop/lid; other site 216591033288 ABC transporter signature motif; other site 216591033289 Walker B; other site 216591033290 D-loop; other site 216591033291 H-loop/switch region; other site 216591033292 TOBE domain; Region: TOBE_2; pfam08402 216591033293 HMMPfam hit to PF00005, ABC transporter, score 5.4e-53 216591033294 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033295 PS00211 ABC transporters family signature. 216591033296 HMMPfam hit to PF03459, TOBE domain, score 2.8e-06 216591033297 HMMPfam hit to PF08402, TOBE domain, score 1.1e-07 216591033298 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 216591033299 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 216591033300 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 4.8e-35 216591033301 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033302 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591033303 dimer interface [polypeptide binding]; other site 216591033304 putative PBP binding loops; other site 216591033305 ABC-ATPase subunit interface; other site 216591033306 6 probable transmembrane helices predicted for BCAS0326 by TMHMM2.0 at aa 31-53, 92-114, 126-145, 172-194, 215-237 and 273-295 216591033307 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.00076 216591033308 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591033309 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 216591033310 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591033311 dimer interface [polypeptide binding]; other site 216591033312 conserved gate region; other site 216591033313 putative PBP binding loops; other site 216591033314 ABC-ATPase subunit interface; other site 216591033315 6 probable transmembrane helices predicted for BCAS0327 by TMHMM2.0 at aa 21-43, 76-98, 111-130, 145-167, 188-210 and 245-267 216591033316 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2e-22 216591033317 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591033318 Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874 216591033319 Beta-galactosidase; Region: Glyco_hydro_42; pfam02449 216591033320 A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143 216591033321 Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533 216591033322 HMMPfam hit to PF02449, Beta-galactosidase, score 1.1e-188 216591033323 HMMPfam hit to PF08532, Beta-galactosidase trimerisation doma, score 1.4e-46 216591033324 HMMPfam hit to PF08533, Beta-galactosidase C-terminal domain, score 8.4e-09 216591033325 sugar efflux transporter; Region: 2A0120; TIGR00899 216591033326 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591033327 11 probable transmembrane helices predicted for BCAS0329 by TMHMM2.0 at aa 21-43, 53-75, 87-109, 114-136, 149-171, 175-197, 239-261, 271-291, 322-344, 359-381 and 388-410 216591033328 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2e-26 216591033329 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033330 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033331 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033332 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033333 Glycosyl hydrolase family 53; Region: Glyco_hydro_53; pfam07745 216591033334 HMMPfam hit to PF07745, Glycosyl hydrolase family, score 2.8e-158 216591033335 1 probable transmembrane helix predicted for BCAS0330 by TMHMM2.0 at aa 13-35 216591033336 2 probable transmembrane helices predicted for BCAS0331 by TMHMM2.0 at aa 20-42 and 47-64 216591033337 Protein of unknown function DUF72; Region: DUF72; pfam01904 216591033338 HMMPfam hit to PF01904, Protein of unknown function DUF72, score 5.9e-81 216591033339 ferrichrome outer membrane transporter; Provisional; Region: PRK10044 216591033340 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591033341 N-terminal plug; other site 216591033342 ligand-binding site [chemical binding]; other site 216591033343 1 probable transmembrane helix predicted for BCAS0333 by TMHMM2.0 at aa 13-35 216591033344 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.1e-20 216591033345 HMMPfam hit to PF00593, TonB dependent receptor, score 2.5e-27 216591033346 Response regulator receiver domain; Region: Response_reg; pfam00072 216591033347 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591033348 active site 216591033349 phosphorylation site [posttranslational modification] 216591033350 intermolecular recognition site; other site 216591033351 dimerization interface [polypeptide binding]; other site 216591033352 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591033353 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591033354 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 4.8e-12 216591033355 PS00041 Bacterial regulatory proteins, araC family signature. 216591033356 Predicted helix-turn-helix motif with score 1605.000, SD 4.65 at aa 171-192, sequence PTVEELARAVGTHEKRLSRAFR 216591033357 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.8e-35 216591033358 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 216591033359 trimer interface [polypeptide binding]; other site 216591033360 Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295 216591033361 YadA-like C-terminal region; Region: YadA; pfam03895 216591033362 1 probable transmembrane helix predicted for BCAS0335 by TMHMM2.0 at aa 7-26 216591033363 HMMPfam hit to PF05658, Hep_Hag, score 1.9 216591033364 HMMPfam hit to PF05658, Hep_Hag, score 0.0094 216591033365 HMMPfam hit to PF05658, Hep_Hag, score 0.09 216591033366 HMMPfam hit to PF05658, Hep_Hag, score 0.00013 216591033367 HMMPfam hit to PF05658, Hep_Hag, score 0.0064 216591033368 HMMPfam hit to PF05662, Haemagglutinin, score 3e-06 216591033369 HMMPfam hit to PF05662, Haemagglutinin, score 0.00011 216591033370 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591033371 HMMPfam hit to PF05662, Haemagglutinin, score 9.5e-06 216591033372 HMMPfam hit to PF05662, Haemagglutinin, score 0.00013 216591033373 HMMPfam hit to PF05662, Haemagglutinin, score 0.00016 216591033374 HMMPfam hit to PF05662, Haemagglutinin, score 7e-05 216591033375 HMMPfam hit to PF05662, Haemagglutinin, score 3.6e-07 216591033376 HMMPfam hit to PF05658, Hep_Hag, score 0.003 216591033377 HMMPfam hit to PF05662, Haemagglutinin, score 6.6e-07 216591033378 HMMPfam hit to PF03895, YadA-like C-terminal region, score 1.3e-30 216591033379 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 216591033380 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587 216591033381 active site 216591033382 metal binding site [ion binding]; metal-binding site 216591033383 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 4.1e-12 216591033384 AAA domain; Region: AAA_17; pfam13207 216591033385 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033386 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033387 Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg3; cd01282 216591033388 transcriptional regulator MerD; Provisional; Region: PRK13749 216591033389 DNA binding residues [nucleotide binding] 216591033390 putative dimer interface [polypeptide binding]; other site 216591033391 HMMPfam hit to PF00376, MerR family regulatory protein, score 4.4e-11 216591033392 Predicted helix-turn-helix motif with score 1280.000, SD 3.55 at aa 10-31, sequence LTIGKLAQLTGASVRSIRHYDE 216591033393 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 216591033394 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 216591033395 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 2.2e-13 216591033396 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 216591033397 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 216591033398 Walker A/P-loop; other site 216591033399 ATP binding site [chemical binding]; other site 216591033400 Q-loop/lid; other site 216591033401 ABC transporter signature motif; other site 216591033402 Walker B; other site 216591033403 D-loop; other site 216591033404 H-loop/switch region; other site 216591033405 HMMPfam hit to PF00005, ABC transporter, score 2.2e-56 216591033406 PS00211 ABC transporters family signature. 216591033407 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033408 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591033409 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591033410 dimer interface [polypeptide binding]; other site 216591033411 conserved gate region; other site 216591033412 putative PBP binding loops; other site 216591033413 ABC-ATPase subunit interface; other site 216591033414 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.5e-22 216591033415 6 probable transmembrane helices predicted for BCAS0341 by TMHMM2.0 at aa 28-50, 87-109, 121-143, 148-167, 209-231 and 241-258 216591033416 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 216591033417 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591033418 substrate binding pocket [chemical binding]; other site 216591033419 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432 216591033420 membrane-bound complex binding site; other site 216591033421 benzoate transport; Region: 2A0115; TIGR00895 216591033422 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591033423 putative substrate translocation pore; other site 216591033424 HMMPfam hit to PF00083, Sugar (and other) transporter, score 5.8e-08 216591033425 12 probable transmembrane helices predicted for BCAS0343 by TMHMM2.0 at aa 39-61, 74-96, 109-131, 135-154, 167-189, 199-218, 276-298, 313-335, 347-366, 371-393, 414-433 and 443-460 216591033426 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.4e-31 216591033427 PS00217 Sugar transport proteins signature 2. 216591033428 FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860 216591033429 nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095 216591033430 active site 216591033431 non-prolyl cis peptide bond; other site 216591033432 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591033433 sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022 216591033434 active site 216591033435 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 1.2e-06 216591033436 sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022 216591033437 Dibenzothiophene (DBT) desulfurization enzyme C; Region: DszC; cd01163 216591033438 Flavin binding site [chemical binding]; other site 216591033439 HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal doma, score 2e-06 216591033440 PS00435 Peroxidases proximal heme-ligand signature. 216591033441 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 1.6e-05 216591033442 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 0.0017 216591033443 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 4.1e-31 216591033444 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591033445 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591033446 dimer interface [polypeptide binding]; other site 216591033447 conserved gate region; other site 216591033448 putative PBP binding loops; other site 216591033449 ABC-ATPase subunit interface; other site 216591033450 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.1e-15 216591033451 7 probable transmembrane helices predicted for BCAS0347 by TMHMM2.0 at aa 26-48, 87-109, 122-144, 148-168, 189-208, 212-234 and 241-263 216591033452 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 216591033453 NMT1-like family; Region: NMT1_2; pfam13379 216591033454 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 216591033455 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 216591033456 Walker A/P-loop; other site 216591033457 ATP binding site [chemical binding]; other site 216591033458 Q-loop/lid; other site 216591033459 ABC transporter signature motif; other site 216591033460 Walker B; other site 216591033461 D-loop; other site 216591033462 H-loop/switch region; other site 216591033463 HMMPfam hit to PF00005, ABC transporter, score 4.9e-63 216591033464 PS00211 ABC transporters family signature. 216591033465 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033466 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 216591033467 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591033468 Uncharacterized conserved protein [Function unknown]; Region: COG2128 216591033469 Carboxymuconolactone decarboxylase family; Region: CMD; cl00460 216591033470 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 7.4e-07 216591033471 Cupin; Region: Cupin_6; pfam12852 216591033472 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591033473 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591033474 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3e-08 216591033475 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.0019 216591033476 galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019 216591033477 active site 216591033478 catalytic residues [active] 216591033479 HMMPfam hit to PF01263, Aldose 1-epimerase, score 6.6e-111 216591033480 PS00545 Aldose 1-epimerase putative active site. 216591033481 Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543 216591033482 putative dimerization interface [polypeptide binding]; other site 216591033483 putative ligand binding site [chemical binding]; other site 216591033484 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591033485 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591033486 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591033487 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 4.7e-07 216591033488 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 9.9e-06 216591033489 Predicted helix-turn-helix motif with score 1388.000, SD 3.91 at aa 308-329, sequence IKTEQVADYVGVSRSLLEEHFR 216591033490 xylose isomerase; Provisional; Region: PRK05474 216591033491 xylose isomerase; Region: xylose_isom_A; TIGR02630 216591033492 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 4.3e-10 216591033493 PS00173 Xylose isomerase signature 2. 216591033494 PS00172 Xylose isomerase signature 1. 216591033495 D-xylose ABC transporter, substrate-binding protein; Region: xylF; TIGR02634 216591033496 Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538 216591033497 putative ligand binding site [chemical binding]; other site 216591033498 1 probable transmembrane helix predicted for BCAS0356 by TMHMM2.0 at aa 9-31 216591033499 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 0.00022 216591033500 xylose transporter ATP-binding subunit; Provisional; Region: PRK13549 216591033501 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 216591033502 Walker A/P-loop; other site 216591033503 ATP binding site [chemical binding]; other site 216591033504 Q-loop/lid; other site 216591033505 ABC transporter signature motif; other site 216591033506 Walker B; other site 216591033507 D-loop; other site 216591033508 H-loop/switch region; other site 216591033509 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 216591033510 HMMPfam hit to PF00005, ABC transporter, score 4.2e-54 216591033511 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033512 HMMPfam hit to PF00005, ABC transporter, score 4.2e-22 216591033513 PS00211 ABC transporters family signature. 216591033514 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591033515 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591033516 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591033517 TM-ABC transporter signature motif; other site 216591033518 9 probable transmembrane helices predicted for BCAS0358 by TMHMM2.0 at aa 35-57, 78-100, 115-137, 144-166, 181-203, 216-238, 243-265, 295-317 and 373-390 216591033519 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 2e-57 216591033520 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 216591033521 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 216591033522 N-terminal plug; other site 216591033523 ligand-binding site [chemical binding]; other site 216591033524 HMMPfam hit to PF00593, TonB dependent receptor, score 1.1e-26 216591033525 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.8e-16 216591033526 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591033527 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591033528 The C-terminal substrate binding domain of LysR-type transcriptional regulators that are involved in the catabolism of dinitrotoluene, naphthalene and gamma-hexachlorohexane; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_NahR_LinR_like; cd08459 216591033529 substrate binding pocket [chemical binding]; other site 216591033530 dimerization interface [polypeptide binding]; other site 216591033531 HMMPfam hit to PF03466, LysR substrate binding domain, score 1e-19 216591033532 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.2e-15 216591033533 PS00044 Bacterial regulatory proteins, lysR family signature. 216591033534 Predicted helix-turn-helix motif with score 2048.000, SD 6.16 at aa 27-48, sequence RSVTRVAEQLGQSQPTVSIWLG 216591033535 2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522 216591033536 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 216591033537 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 216591033538 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 7.1e-05 216591033539 HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 1.3e-51 216591033540 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033541 HMMPfam hit to PF08546, Ketopantoate reductase PanE/ApbA C ter, score 8.5e-46 216591033542 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033543 Glyoxalase-like domain; Region: Glyoxalase_2; pfam12681 216591033544 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 0.0013 216591033545 (R)-hydratase [(R)-specific enoyl-CoA hydratase]. Catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway. The structure of the monomer includes a five-strand antiparallel...; Region: R_hydratase_like; cd03441 216591033546 active site 216591033547 catalytic site [active] 216591033548 PS00061 Short-chain dehydrogenases/reductases family signature. 216591033549 HMMPfam hit to PF01575, MaoC like domain, score 1.2e-09 216591033550 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591033551 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 216591033552 CoA-transferase family III; Region: CoA_transf_3; pfam02515 216591033553 HMMPfam hit to PF02515, CoA-transferase family III, score 4.3e-54 216591033554 shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258 216591033555 Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501 216591033556 NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065 216591033557 shikimate binding site; other site 216591033558 NAD(P) binding site [chemical binding]; other site 216591033559 HMMPfam hit to PF08501, Shikimate dehydrogenase substrate bind, score 2.9e-25 216591033560 HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase, score 2.1e-22 216591033561 citrate-proton symporter; Provisional; Region: PRK15075 216591033562 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591033563 putative substrate translocation pore; other site 216591033564 HMMPfam hit to PF00083, Sugar (and other) transporter, score 3.5e-50 216591033565 11 probable transmembrane helices predicted for BCAS0367 by TMHMM2.0 at aa 60-82, 94-116, 126-148, 169-186, 190-212, 244-266, 281-303, 310-332, 342-364, 371-393 and 408-425 216591033566 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033567 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.2e-23 216591033568 PS00216 Sugar transport proteins signature 1. 216591033569 PS00217 Sugar transport proteins signature 2. 216591033570 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033571 PS00216 Sugar transport proteins signature 1. 216591033572 tricarballylate utilization protein B; Provisional; Region: PRK15033 216591033573 6 probable transmembrane helices predicted for BCAS0368 by TMHMM2.0 at aa 134-156, 171-193, 251-273, 283-305, 326-343 and 348-370 216591033574 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0019 216591033575 tricarballylate dehydrogenase; Validated; Region: PRK08274 216591033576 HMMPfam hit to PF00890, FAD binding domain, score 1.1e-10 216591033577 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2.6e-06 216591033578 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591033579 The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433 216591033580 putative dimerization interface [polypeptide binding]; other site 216591033581 HMMPfam hit to PF03466, LysR substrate binding domain, score 5.6e-33 216591033582 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 7.7e-19 216591033583 PS00044 Bacterial regulatory proteins, lysR family signature. 216591033584 Predicted helix-turn-helix motif with score 1323.000, SD 3.69 at aa 16-37, sequence GSMGKAALELGVVTSALSQQIS 216591033585 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591033586 Fumarylacetoacetate (FAA) hydrolase family protein [General function prediction only]; Region: COG3970 216591033587 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 216591033588 dihydroxy-acid dehydratase; Provisional; Region: PRK13017 216591033589 HMMPfam hit to PF00920, Dehydratase family, score 2.3e-218 216591033590 PS00061 Short-chain dehydrogenases/reductases family signature. 216591033591 PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 216591033592 Transcriptional regulators [Transcription]; Region: PurR; COG1609 216591033593 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 216591033594 DNA binding site [nucleotide binding] 216591033595 domain linker motif; other site 216591033596 Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575 216591033597 putative dimerization interface [polypeptide binding]; other site 216591033598 putative ligand binding site [chemical binding]; other site 216591033599 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 4.8e-11 216591033600 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 6.9e-10 216591033601 PS00435 Peroxidases proximal heme-ligand signature. 216591033602 Predicted helix-turn-helix motif with score 1870.000, SD 5.56 at aa 13-34, sequence PRMSDVARLAGVSKMTVSRVLA 216591033603 PS00356 Bacterial regulatory proteins, lacI family signature. 216591033604 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591033605 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591033606 putative substrate translocation pore; other site 216591033607 12 probable transmembrane helices predicted for BCAS0374 by TMHMM2.0 at aa 29-50, 65-87, 94-116, 131-153, 160-182, 197-219, 261-283, 293-315, 327-346, 350-372, 379-401 and 416-438 216591033608 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.3e-39 216591033609 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033610 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033611 Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436 216591033612 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 216591033613 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591033614 homodimer interface [polypeptide binding]; other site 216591033615 catalytic residue [active] 216591033616 HMMPfam hit to PF00155, Aminotransferase class I and II, score 5.9e-23 216591033617 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591033618 Transcriptional regulators [Transcription]; Region: GntR; COG1802 216591033619 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591033620 DNA-binding site [nucleotide binding]; DNA binding site 216591033621 FCD domain; Region: FCD; pfam07729 216591033622 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 3.3e-18 216591033623 HMMPfam hit to PF07729, FCD domain, score 1.7e-10 216591033624 Short repeat of unknown function (DUF308); Region: DUF308; cl15828 216591033625 6 probable transmembrane helices predicted for BCAS0377 by TMHMM2.0 at aa 20-39, 43-65, 78-95, 99-121, 128-150 and 160-182 216591033626 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 216591033627 Zn2+ binding site [ion binding]; other site 216591033628 Mg2+ binding site [ion binding]; other site 216591033629 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 216591033630 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591033631 DNA binding residues [nucleotide binding] 216591033632 dimerization interface [polypeptide binding]; other site 216591033633 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 3.8e-14 216591033634 HMMPfam hit to PF04967, HTH DNA binding domain, score 0.0026 216591033635 Predicted helix-turn-helix motif with score 1414.000, SD 4.00 at aa 446-467, sequence ASNKQVAQALAMSPSTVRTHVE 216591033636 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591033637 13 probable transmembrane helices predicted for BCAS0379 by TMHMM2.0 at aa 15-37, 82-104, 114-133, 140-162, 172-194, 207-224, 234-251, 276-298, 308-330, 337-359, 369-388, 409-431 and 446-468 216591033638 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.1e-45 216591033639 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591033640 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033641 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 4.6e-09 216591033642 succinic semialdehyde dehydrogenase; Region: PLN02278 216591033643 Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103 216591033644 tetramerization interface [polypeptide binding]; other site 216591033645 NAD(P) binding site [chemical binding]; other site 216591033646 catalytic residues [active] 216591033647 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 7e-220 216591033648 PS00687 Aldehyde dehydrogenases glutamic acid active site. 216591033649 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591033650 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591033651 putative DNA binding site [nucleotide binding]; other site 216591033652 putative Zn2+ binding site [ion binding]; other site 216591033653 AsnC family; Region: AsnC_trans_reg; pfam01037 216591033654 HMMPfam hit to PF01037, AsnC family, score 7.7e-24 216591033655 PS00519 Bacterial regulatory proteins, asnC family signature. 216591033656 Predicted helix-turn-helix motif with score 1117.000, SD 2.99 at aa 29-50, sequence MTNVELADAVGLSPSPCLIRVK 216591033657 hypothetical protein; Provisional; Region: PRK05965 216591033658 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 216591033659 inhibitor-cofactor binding pocket; inhibition site 216591033660 pyridoxal 5'-phosphate binding site [chemical binding]; other site 216591033661 catalytic residue [active] 216591033662 HMMPfam hit to PF00202, Aminotransferase class-III, score 2.1e-93 216591033663 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216591033664 Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111 216591033665 Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164 216591033666 putative ligand binding site [chemical binding]; other site 216591033667 NAD binding site [chemical binding]; other site 216591033668 dimerization interface [polypeptide binding]; other site 216591033669 catalytic site [active] 216591033670 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 4.8e-47 216591033671 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591033672 Coenzyme A binding pocket [chemical binding]; other site 216591033673 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 7.9e-15 216591033674 2-haloalkanoic acid dehalogenase, type II; Region: HAD_type_II; TIGR01428 216591033675 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 216591033676 motif II; other site 216591033677 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 8.6e-10 216591033678 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 216591033679 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_17; cd08503 216591033680 2 probable transmembrane helices predicted for BCAS0388 by TMHMM2.0 at aa 32-54 and 514-536 216591033681 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 1.8e-65 216591033682 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 216591033683 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591033684 dimer interface [polypeptide binding]; other site 216591033685 conserved gate region; other site 216591033686 putative PBP binding loops; other site 216591033687 ABC-ATPase subunit interface; other site 216591033688 6 probable transmembrane helices predicted for BCAS0389 by TMHMM2.0 at aa 13-35, 104-126, 139-161, 181-198, 243-265 and 285-307 216591033689 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.9e-41 216591033690 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173 216591033691 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591033692 dimer interface [polypeptide binding]; other site 216591033693 conserved gate region; other site 216591033694 ABC-ATPase subunit interface; other site 216591033695 6 probable transmembrane helices predicted for BCAS0390 by TMHMM2.0 at aa 50-72, 76-95, 116-138, 161-183, 236-258 and 278-300 216591033696 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3.7e-32 216591033697 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 216591033698 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444 216591033699 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591033700 Walker A/P-loop; other site 216591033701 ATP binding site [chemical binding]; other site 216591033702 Q-loop/lid; other site 216591033703 ABC transporter signature motif; other site 216591033704 Walker B; other site 216591033705 D-loop; other site 216591033706 H-loop/switch region; other site 216591033707 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352 216591033708 HMMPfam hit to PF00005, ABC transporter, score 5.7e-58 216591033709 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033710 PS00211 ABC transporters family signature. 216591033711 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 1.2e-06 216591033712 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 216591033713 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591033714 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.2e-93 216591033715 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591033716 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591033717 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591033718 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 8.2e-05 216591033719 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00019 216591033720 Protein of unknown function (DUF861); Region: Cupin_3; pfam05899 216591033721 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 216591033722 HMMPfam hit to PF05899, Protein of unknown function (DUF861), score 1.7e-05 216591033723 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 216591033724 hydroxyglutarate oxidase; Provisional; Region: PRK11728 216591033725 1 probable transmembrane helix predicted for BCAS0395 by TMHMM2.0 at aa 15-37 216591033726 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 3e-104 216591033727 PS00237 G-protein coupled receptors signature. 216591033728 Rhodococcus ruber 6-oxolauric acid dehydrogenase-like; Region: ALDH_CddD_SSP0762; cd07138 216591033729 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 216591033730 NAD binding site [chemical binding]; other site 216591033731 catalytic residues [active] 216591033732 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 5.7e-214 216591033733 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033734 PS00070 Aldehyde dehydrogenases cysteine active site. 216591033735 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 216591033736 M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666 216591033737 metal binding site [ion binding]; metal-binding site 216591033738 putative dimer interface [polypeptide binding]; other site 216591033739 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 6.7e-63 216591033740 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 2e-07 216591033741 Cache domain; Region: Cache_1; pfam02743 216591033742 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591033743 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591033744 metal binding site [ion binding]; metal-binding site 216591033745 active site 216591033746 I-site; other site 216591033747 HMMPfam hit to PF00990, GGDEF domain, score 1e-58 216591033748 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033749 2 probable transmembrane helices predicted for BCAS0398 by TMHMM2.0 at aa 20-42 and 296-318 216591033750 PS00044 Bacterial regulatory proteins, lysR family signature. 216591033751 citrate-proton symporter; Provisional; Region: PRK15075 216591033752 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591033753 putative substrate translocation pore; other site 216591033754 HMMPfam hit to PF00083, Sugar (and other) transporter, score 1.9e-47 216591033755 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.5e-23 216591033756 10 probable transmembrane helices predicted for BCAS0399 by TMHMM2.0 at aa 53-70, 80-102, 123-145, 207-229, 261-283, 298-320, 327-349, 359-381, 388-410 and 425-442 216591033757 PS00216 Sugar transport proteins signature 1. 216591033758 PS00217 Sugar transport proteins signature 2. 216591033759 PS00216 Sugar transport proteins signature 1. 216591033760 Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531 216591033761 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 216591033762 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 0.00058 216591033763 Sodium:dicarboxylate symporter family; Region: SDF; cl00573 216591033764 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 216591033765 HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 5.6e-129 216591033766 8 probable transmembrane helices predicted for BCAS0401 by TMHMM2.0 at aa 9-28, 43-65, 78-100, 143-165, 186-208, 223-245, 315-337 and 352-374 216591033767 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033768 PS00714 Sodium:dicarboxylate symporter family signature 2. 216591033769 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591033770 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591033771 TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440 216591033772 putative dimerization interface [polypeptide binding]; other site 216591033773 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.5e-53 216591033774 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.7e-24 216591033775 PS00044 Bacterial regulatory proteins, lysR family signature. 216591033776 Predicted helix-turn-helix motif with score 1554.000, SD 4.48 at aa 26-47, sequence GSFRKAADAISLSQPALSRRID 216591033777 Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692 216591033778 1 probable transmembrane helix predicted for BCAS0404 by TMHMM2.0 at aa 7-29 216591033779 Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056 216591033780 active site 216591033781 catalytic triad [active] 216591033782 calcium binding site [ion binding]; other site 216591033783 1 probable transmembrane helix predicted for BCAS0405 by TMHMM2.0 at aa 13-30 216591033784 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 216591033785 Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505 216591033786 Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227 216591033787 Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504 216591033788 Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597 216591033789 active site 216591033790 Zn binding site [ion binding]; other site 216591033791 HMMPfam hit to PF07504, Fungalysin/Thermolysin Propeptide Moti, score 7.8e-13 216591033792 HMMPfam hit to PF01447, Thermolysin metallopeptidase, catalyti, score 4.3e-09 216591033793 PS00201 Flavodoxin signature. 216591033794 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591033795 HMMPfam hit to PF02868, Thermolysin metallopeptidase, alpha-he, score 5.9e-38 216591033796 3 probable transmembrane helices predicted for BCAS0412 by TMHMM2.0 at aa 9-31, 41-63 and 83-105 216591033797 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033798 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 216591033799 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591033800 substrate binding pocket [chemical binding]; other site 216591033801 membrane-bound complex binding site; other site 216591033802 Protein of unknown function (DUF3088); Region: DUF3088; pfam11287 216591033803 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591033804 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591033805 trimer interface [polypeptide binding]; other site 216591033806 eyelet of channel; other site 216591033807 HMMPfam hit to PF00267, Gram-negative porin, score 5e-06 216591033808 Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199 216591033809 Moco binding site; other site 216591033810 metal coordination site [ion binding]; other site 216591033811 HMMPfam hit to PF00174, Oxidoreductase molybdopterin binding d, score 5.6e-69 216591033812 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033813 HMMPfam hit to PF03404, Mo-co oxidoreductase dimerisation doma, score 1.4e-19 216591033814 Cytochrome c; Region: Cytochrom_C; cl11414 216591033815 HMMPfam hit to PF00034, Cytochrome c, score 0.0011 216591033816 PS00190 Cytochrome c family heme-binding site signature. 216591033817 Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094 216591033818 active site 216591033819 dimethyl sulfone monooxygenase SfnG; Region: LLM_DMSO2_sfnG; TIGR04021 216591033820 dimer interface [polypeptide binding]; other site 216591033821 non-prolyl cis peptide bond; other site 216591033822 insertion regions; other site 216591033823 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 4.4e-06 216591033824 Dibenzothiophene (DBT) desulfurization enzyme C; Region: DszC; cd01163 216591033825 sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022 216591033826 Flavin binding site [chemical binding]; other site 216591033827 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 7e-06 216591033828 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 216591033829 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591033830 putative PBP binding loops; other site 216591033831 dimer interface [polypeptide binding]; other site 216591033832 ABC-ATPase subunit interface; other site 216591033833 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.2e-07 216591033834 8 probable transmembrane helices predicted for BCAS0420 by TMHMM2.0 at aa 45-67, 71-93, 100-122, 142-164, 169-187, 202-224, 229-251 and 261-280 216591033835 CDS interrupted by IS element after codon 171. Similar to Pseudomonas putida ABC transporter, ATP-binding protein SWALL:Q88RF9 (EMBL:AE016774) (287 aa) fasta scores: E(): 1.4e-66, 75.68% id in 255 aa; has 20 amino acid N terminal truncation. Similar to Synechococcus sp. nitrate transport ATP-binding protein NrtD nrtD SWALL:NRTD_SYNP7 (SWALL:P38046) (274 aa) fasta scores: E(): 1.4e-28, 47.26% id in 201 aa; homology does not extend to N and C termini 216591033836 HMMPfam hit to PF00005, ABC transporter, score 1.9e-55 216591033837 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591033838 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591033839 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591033840 HMMPfam hit to PF01548, Transposase, score 2.9e-12 216591033841 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 2e-19 216591033842 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033843 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 216591033844 NMT1-like family; Region: NMT1_2; pfam13379 216591033845 1 probable transmembrane helix predicted for BCAS0425 by TMHMM2.0 at aa 7-26 216591033846 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 216591033847 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 216591033848 HMMPfam hit to PF02668, Taurine catabolism dioxygenase TauD, TfdA fa, score 5.3e-80 216591033849 oxidoreductase; Provisional; Region: PRK06128 216591033850 classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355 216591033851 NAD binding site [chemical binding]; other site 216591033852 metal binding site [ion binding]; metal-binding site 216591033853 active site 216591033854 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0028 216591033855 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.3e-24 216591033856 PS00061 Short-chain dehydrogenases/reductases family signature. 216591033857 Protein of unknown function (DUF2934); Region: DUF2934; pfam11154 216591033858 FOG: CBS domain [General function prediction only]; Region: COG0517 216591033859 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_9; cd04622 216591033860 HMMPfam hit to PF00571, CBS domain pair, score 3.3e-32 216591033861 MgtC family; Region: MgtC; pfam02308 216591033862 HMMPfam hit to PF02308, MgtC family, score 8.1e-23 216591033863 5 probable transmembrane helices predicted for BCAS0432 by TMHMM2.0 at aa 10-29, 42-64, 79-96, 101-123 and 127-146 216591033864 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591033865 non-specific DNA binding site [nucleotide binding]; other site 216591033866 salt bridge; other site 216591033867 sequence-specific DNA binding site [nucleotide binding]; other site 216591033868 HMMPfam hit to PF01381, Helix-turn-helix, score 2.4e-07 216591033869 Predicted helix-turn-helix motif with score 1562.000, SD 4.51 at aa 26-47, sequence FTRDELANATGLSPKFISQVEA 216591033870 HipA N-terminal domain; Region: Couple_hipA; pfam13657 216591033871 HipA-like N-terminal domain; Region: HipA_N; pfam07805 216591033872 HipA-like C-terminal domain; Region: HipA_C; pfam07804 216591033873 HMMPfam hit to PF07805, HipA-like N-terminal domain, score 1.5e-14 216591033874 HMMPfam hit to PF07804, HipA-like C-terminal domain, score 1.1e-25 216591033875 oxidoreductase; Provisional; Region: PRK06196 216591033876 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591033877 NAD(P) binding site [chemical binding]; other site 216591033878 active site 216591033879 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.6e-06 216591033880 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033881 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033882 Cupin; Region: Cupin_6; pfam12852 216591033883 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591033884 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591033885 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591033886 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.2e-07 216591033887 Predicted helix-turn-helix motif with score 1216.000, SD 3.33 at aa 215-236, sequence WTVDALAACCHVSRSTFALHFK 216591033888 PS00041 Bacterial regulatory proteins, araC family signature. 216591033889 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.5e-11 216591033890 OsmC-like protein; Region: OsmC; pfam02566 216591033891 HMMPfam hit to PF02566, OsmC-like protein, score 5.7e-13 216591033892 Methylthioribose-binding protein-like of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_methylthioribose_binding_like; cd06305 216591033893 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 216591033894 putative ligand binding site [chemical binding]; other site 216591033895 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 0.00028 216591033896 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 216591033897 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 216591033898 TM-ABC transporter signature motif; other site 216591033899 10 probable transmembrane helices predicted for BCAS0439 by TMHMM2.0 at aa 21-40, 55-77, 79-98, 103-125, 134-156, 182-204, 237-259, 263-285, 292-311 and 315-337 216591033900 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.2e-52 216591033901 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033902 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591033903 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 216591033904 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 216591033905 Walker A/P-loop; other site 216591033906 ATP binding site [chemical binding]; other site 216591033907 Q-loop/lid; other site 216591033908 ABC transporter signature motif; other site 216591033909 Walker B; other site 216591033910 D-loop; other site 216591033911 H-loop/switch region; other site 216591033912 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 216591033913 HMMPfam hit to PF00005, ABC transporter, score 1.2e-20 216591033914 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033915 HMMPfam hit to PF00005, ABC transporter, score 1.4e-50 216591033916 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033917 FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860 216591033918 nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095 216591033919 active site 216591033920 non-prolyl cis peptide bond; other site 216591033921 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591033922 dimer interface [polypeptide binding]; other site 216591033923 conserved gate region; other site 216591033924 putative PBP binding loops; other site 216591033925 ABC-ATPase subunit interface; other site 216591033926 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.7e-20 216591033927 5 probable transmembrane helices predicted for BCAS0442 by TMHMM2.0 at aa 23-45, 58-80, 100-119, 157-179 and 201-223 216591033928 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591033929 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427 216591033930 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591033931 putative PBP binding loops; other site 216591033932 dimer interface [polypeptide binding]; other site 216591033933 ABC-ATPase subunit interface; other site 216591033934 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.3e-18 216591033935 4 probable transmembrane helices predicted for BCAS0443 by TMHMM2.0 at aa 24-46, 67-89, 104-123 and 207-229 216591033936 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 216591033937 Predicted helix-turn-helix motif with score 1083.000, SD 2.88 at aa 136-157, sequence VGQIEAAHAYGMTPWQTFTRIR 216591033938 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591033939 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591033940 substrate binding pocket [chemical binding]; other site 216591033941 membrane-bound complex binding site; other site 216591033942 hinge residues; other site 216591033943 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.5e-59 216591033944 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892 216591033945 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141 216591033946 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892 216591033947 luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558 216591033948 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 2.5e-10 216591033949 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 216591033950 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591033951 Coenzyme A binding pocket [chemical binding]; other site 216591033952 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.4e-05 216591033953 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 216591033954 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_15; cd08492 216591033955 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 2.1e-72 216591033956 PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 216591033957 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 216591033958 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427 216591033959 6 probable transmembrane helices predicted for BCAS0449 by TMHMM2.0 at aa 32-54, 129-151, 163-185, 195-217, 253-275 and 303-325 216591033960 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.8e-37 216591033961 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173 216591033962 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591033963 dimer interface [polypeptide binding]; other site 216591033964 conserved gate region; other site 216591033965 putative PBP binding loops; other site 216591033966 ABC-ATPase subunit interface; other site 216591033967 6 probable transmembrane helices predicted for BCAS0450 by TMHMM2.0 at aa 26-48, 93-115, 136-158, 173-195, 208-230 and 257-279 216591033968 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.1e-42 216591033969 ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123 216591033970 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591033971 Walker A/P-loop; other site 216591033972 ATP binding site [chemical binding]; other site 216591033973 Q-loop/lid; other site 216591033974 ABC transporter signature motif; other site 216591033975 Walker B; other site 216591033976 D-loop; other site 216591033977 H-loop/switch region; other site 216591033978 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352 216591033979 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 216591033980 Walker A/P-loop; other site 216591033981 ATP binding site [chemical binding]; other site 216591033982 Q-loop/lid; other site 216591033983 ABC transporter signature motif; other site 216591033984 Walker B; other site 216591033985 D-loop; other site 216591033986 H-loop/switch region; other site 216591033987 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 216591033988 HMMPfam hit to PF00005, ABC transporter, score 9.6e-41 216591033989 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033990 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 8.8e-07 216591033991 HMMPfam hit to PF00005, ABC transporter, score 6.9e-66 216591033992 PS00017 ATP/GTP-binding site motif A (P-loop). 216591033993 PS00211 ABC transporters family signature. 216591033994 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 7.2e-05 216591033995 Protein of unknown function (DUF2909); Region: DUF2909; pfam11137 216591033996 2 probable transmembrane helices predicted for BCAS0452 by TMHMM2.0 at aa 4-26 and 39-61 216591033997 1 probable transmembrane helix predicted for BCAS0453 by TMHMM2.0 at aa 15-37 216591033998 Protein of unknown function (DUF1275); Region: DUF1275; pfam06912 216591033999 HMMPfam hit to PF06912, Protein of unknown function (DUF1275), score 3.8e-46 216591034000 6 probable transmembrane helices predicted for BCAS0454 by TMHMM2.0 at aa 22-41, 66-88, 100-122, 126-148, 198-216 and 226-248 216591034001 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034002 Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402 216591034003 HMMPfam hit to PF01402, Ribbon-helix-helix protein, copG family, score 4.9e-06 216591034004 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 216591034005 S-adenosylmethionine binding site [chemical binding]; other site 216591034006 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824 216591034007 PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274 216591034008 PhnA protein; Region: PhnA; pfam03831 216591034009 HMMPfam hit to PF03831, PhnA protein, score 1.9e-28 216591034010 HMMPfam hit to PF08274, PhnA Zinc-Ribbon, score 7.7e-13 216591034011 Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367 216591034012 regulatory phosphorylation site [posttranslational modification]; other site 216591034013 HMMPfam hit to PF00381, PTS HPr component phosphorylation site, score 0.00046 216591034014 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 216591034015 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 216591034016 trimer interface [polypeptide binding]; other site 216591034017 eyelet of channel; other site 216591034018 HMMPfam hit to PF00267, Gram-negative porin, score 0.00052 216591034019 TM1410 hypothetical-related protein; Region: DUF297; pfam03537 216591034020 HMMPfam hit to PF03537, TM1410 hypothetical-related protein, score 5.2e-06 216591034021 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034022 Melibiase; Region: Melibiase; pfam02065 216591034023 HMMPfam hit to PF02065, Melibiase, score 1.3e-06 216591034024 EamA-like transporter family; Region: EamA; cl17759 216591034025 10 probable transmembrane helices predicted for BCAS0463 by TMHMM2.0 at aa 5-24, 34-53, 65-87, 92-114, 121-138, 148-167, 180-199, 209-231, 238-260 and 270-292 216591034026 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.9e-09 216591034027 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.1e-05 216591034028 Tagatose 6 phosphate kinase; Region: Tagatose_6_P_K; cl09211 216591034029 HMMPfam hit to PF08013, Tagatose 6 phosphate kinase, score 2.3e-231 216591034030 putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815 216591034031 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 216591034032 dimer interface [polypeptide binding]; other site 216591034033 active site 216591034034 SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389 216591034035 HMMPfam hit to PF01380, SIS domain, score 0.0011 216591034036 HMMPfam hit to PF01380, SIS domain, score 0.0013 216591034037 PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1. 216591034038 Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism]; Region: COG2971 216591034039 HMMPfam hit to PF01869, BadF/BadG/BcrA/BcrD ATPase family, score 3.7e-44 216591034040 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 216591034041 DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220 216591034042 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 216591034043 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 0.0023 216591034044 HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 8.6e-19 216591034045 HMMPfam hit to PF08279, HTH domain, score 5.8e-06 216591034046 Predicted helix-turn-helix motif with score 1556.000, SD 4.49 at aa 36-57, sequence VTVEELAERFGISLVTVRSDLN 216591034047 HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 5.8e-49 216591034048 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 216591034049 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.1e-06 216591034050 DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701 216591034051 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591034052 active site 216591034053 phosphorylation site [posttranslational modification] 216591034054 intermolecular recognition site; other site 216591034055 dimerization interface [polypeptide binding]; other site 216591034056 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591034057 DNA binding site [nucleotide binding] 216591034058 HMMPfam hit to PF00072, Response regulator receiver domain, score 3.2e-26 216591034059 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 5.2e-16 216591034060 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591034061 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.4e-37 216591034062 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.5e-20 216591034063 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034064 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 216591034065 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591034066 putative substrate translocation pore; other site 216591034067 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361 216591034068 13 probable transmembrane helices predicted for BCAS0472 by TMHMM2.0 at aa 21-43, 63-85, 90-112, 149-171, 178-195, 210-232, 245-267, 282-304, 311-333, 343-362, 383-400, 410-432 and 494-516 216591034069 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.6e-54 216591034070 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034071 PS00092 N-6 Adenine-specific DNA methylases signature. 216591034072 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591034073 Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566 216591034074 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591034075 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.7e-46 216591034076 1 probable transmembrane helix predicted for BCAS0473 by TMHMM2.0 at aa 124-146 216591034077 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_10; cd04667 216591034078 nudix motif; other site 216591034079 HMMPfam hit to PF00293, NUDIX domain, score 4.4e-21 216591034080 PS00893 mutT domain signature. 216591034081 Predicted helix-turn-helix motif with score 1002.000, SD 2.60 at aa 150-171, sequence RQFADLCAACGLSPAPVKRLSS 216591034082 BON domain; Region: BON; pfam04972 216591034083 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 2.1e-07 216591034084 1 probable transmembrane helix predicted for BCAS0477 by TMHMM2.0 at aa 10-27 216591034085 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034086 Low affinity iron permease; Region: Iron_permease; pfam04120 216591034087 HMMPfam hit to PF07300, Protein of unknown function (DUF1452), score 4.7e-51 216591034088 2 probable transmembrane helices predicted for BCAS0478 by TMHMM2.0 at aa 40-62 and 72-91 216591034089 FRG domain; Region: FRG; pfam08867 216591034090 Domain of unknown function (DUF305); Region: DUF305; cl17794 216591034091 HMMPfam hit to PF03713, Domain of unknown function (DUF305), score 1.9e-23 216591034092 Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303 216591034093 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 216591034094 HMMPfam hit to PF05199, GMC oxidoreductase, score 0.00057 216591034095 HMMPfam hit to PF00732, GMC oxidoreductase, score 2.6e-13 216591034096 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034097 Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618 216591034098 6 probable transmembrane helices predicted for BCAS0483 by TMHMM2.0 at aa 82-99, 114-136, 149-171, 186-206, 218-240 and 255-277 216591034099 Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188 216591034100 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948 216591034101 metal binding site [ion binding]; metal-binding site 216591034102 substrate binding pocket [chemical binding]; other site 216591034103 HMMPfam hit to PF01188, Mandelate racemase / muconate lactonizing en, score 5.2e-09 216591034104 HMMPfam hit to PF02746, Mandelate racemase / muconate lactonizing en, score 1.6e-05 216591034105 PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 216591034106 thiamine pyrophosphate protein; Provisional; Region: PRK08273 216591034107 Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039 216591034108 PYR/PP interface [polypeptide binding]; other site 216591034109 dimer interface [polypeptide binding]; other site 216591034110 tetramer interface [polypeptide binding]; other site 216591034111 TPP binding site [chemical binding]; other site 216591034112 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 216591034113 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629 216591034114 TPP-binding site [chemical binding]; other site 216591034115 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 4.7e-50 216591034116 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 8.5e-18 216591034117 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 7.9e-24 216591034118 PS00187 Thiamine pyrophosphate enzymes signature. 216591034119 Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387 216591034120 Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723 216591034121 HMMPfam hit to PF00723, Glycosyl hydrolases family, score 8.8e-85 216591034122 short chain dehydrogenase; Provisional; Region: PRK09072 216591034123 classical (c) SDR, subgroup 3; Region: SDR_c3; cd05360 216591034124 putative NAD(P) binding site [chemical binding]; other site 216591034125 active site 216591034126 1 probable transmembrane helix predicted for BCAS0487 by TMHMM2.0 at aa 300-322 216591034127 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.1e-26 216591034128 PS00061 Short-chain dehydrogenases/reductases family signature. 216591034129 cytochrome c oxidase, subunit II; Region: CoxB; TIGR02866 216591034130 Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116 216591034131 Cytochrome c; Region: Cytochrom_C; pfam00034 216591034132 3 probable transmembrane helices predicted for BCAS0488 by TMHMM2.0 at aa 12-34, 64-86 and 99-121 216591034133 HMMPfam hit to PF00116, Cytochrome C oxidase subunit II, periplas, score 1.2e-20 216591034134 PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 216591034135 HMMPfam hit to PF00034, Cytochrome c, score 0.0048 216591034136 PS00190 Cytochrome c family heme-binding site signature. 216591034137 Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843 216591034138 Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662 216591034139 D-pathway; other site 216591034140 Putative ubiquinol binding site [chemical binding]; other site 216591034141 Low-spin heme (heme b) binding site [chemical binding]; other site 216591034142 Putative water exit pathway; other site 216591034143 Binuclear center (heme o3/CuB) [ion binding]; other site 216591034144 K-pathway; other site 216591034145 Putative proton exit pathway; other site 216591034146 Heme-copper oxidase subunit III. Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cd00386 216591034147 HMMPfam hit to PF00115, Cytochrome C and Quinol oxidase polypeptide, score 6.8e-177 216591034148 19 probable transmembrane helices predicted for BCAS0489 by TMHMM2.0 at aa 52-74, 100-122, 135-157, 182-204, 225-247, 267-289, 302-324, 339-361, 373-395, 410-432, 444-466, 489-511, 600-617, 622-639, 702-724, 739-758, 771-793, 808-830 and 851-873 216591034149 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591034150 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034151 HMMPfam hit to PF00510, Cytochrome c oxidase subunit III, score 7.2e-11 216591034152 3 probable transmembrane helices predicted for BCAS0490 by TMHMM2.0 at aa 7-29, 55-77 and 104-126 216591034153 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034154 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591034155 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 216591034156 Cytochrome c; Region: Cytochrom_C; pfam00034 216591034157 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034158 PS00190 Cytochrome c family heme-binding site signature. 216591034159 PS00190 Cytochrome c family heme-binding site signature. 216591034160 HMMPfam hit to PF00034, Cytochrome c, score 9.3e-05 216591034161 YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198 216591034162 homotrimer interaction site [polypeptide binding]; other site 216591034163 putative active site [active] 216591034164 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 6.4e-36 216591034165 CDS contains a frameshift after codon 188. Similar to Acinetobacter sp. (strain adp1) 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase BenD UniProt:P07772 (EMBL:AF009224 (261 aa) fasta scores: E()=1e-48, 57.915% id in 259 aa 216591034166 HMMPfam hit to PF00106, short chain dehydrogenase, score 4.1e-13 216591034167 PS00061 Short-chain dehydrogenases/reductases family signature. 216591034168 anthranilate dioxygenase reductase; Provisional; Region: antC; PRK11872 216591034169 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 216591034170 catalytic loop [active] 216591034171 iron binding site [ion binding]; other site 216591034172 Benzoate dioxygenase reductase (BenDO) FAD/NAD binding domain. Oxygenases oxidize hydrocarbons using dioxygen as the oxidant. As a Class I bacterial dioxygenases, benzoate dioxygenase like proteins combine an [2Fe-2S] cluster containing N-terminal...; Region: BenDO_FAD_NAD; cd06209 216591034173 FAD binding pocket [chemical binding]; other site 216591034174 FAD binding motif [chemical binding]; other site 216591034175 phosphate binding motif [ion binding]; other site 216591034176 beta-alpha-beta structure motif; other site 216591034177 NAD binding pocket [chemical binding]; other site 216591034178 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 1.6e-30 216591034179 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 6.1e-22 216591034180 HMMPfam hit to PF08021, Siderophore-interacting FAD-binding dom, score 0.0031 216591034181 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034182 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 1.1e-18 216591034183 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 216591034184 Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667 216591034185 inter-subunit interface; other site 216591034186 HMMPfam hit to PF00866, Ring hydroxylating beta subunit, score 2.4e-69 216591034187 benzoate 1,2-dioxygenase, large subunit; Region: benzo_1_2_benA; TIGR03229 216591034188 Rieske non-heme iron oxygenase (RO) family, 2-Halobenzoate 1,2-dioxygenase (HBDO) subfamily, N-terminal Rieske domain of the oxygenase alpha subunit; ROs comprise a large class of aromatic ring-hydroxylating dioxygenases that enable microorganisms to...; Region: Rieske_RO_Alpha_HBDO; cd03542 216591034189 C-terminal catalytic domain of the oxygenase alpha subunit of Pseudomonas resinovorans strain CA10 anthranilate 1,2-dioxygenase and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_AntDO-like; cd08879 216591034190 putative alpha subunit interface [polypeptide binding]; other site 216591034191 putative active site [active] 216591034192 putative substrate binding site [chemical binding]; other site 216591034193 Fe binding site [ion binding]; other site 216591034194 HMMPfam hit to PF00848, Ring hydroxylating alpha subunit (cat, score 8.8e-22 216591034195 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 1.8e-32 216591034196 catechol 1,2-dioxygenase, proteobacterial; Region: catechol_proteo; TIGR02439 216591034197 Catechol 1,2 dioxygenase (1,2-CTD) catalyzes an intradiol cleavage reaction of catechol to form cis,cis-muconate. 1,2-CTDs is homodimers with one catalytic non-heme ferric ion per monomer. They belong to the aromatic dioxygenase family, a family of...; Region: 1,2-CTD; cd03460 216591034198 dimer interface [polypeptide binding]; other site 216591034199 active site 216591034200 HMMPfam hit to PF00775, Dioxygenase, score 4.4e-107 216591034201 PS00083 Intradiol ring-cleavage dioxygenases signature. 216591034202 HMMPfam hit to PF04444, Catechol dioxygenase N terminus, score 2.3e-40 216591034203 Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis,cis-muconate (CCM) to muconolactone (ML) in the catechol branch of the beta-ketoadipate pathway. This pathway is used in soil microbes to breakdown lignin-derived...; Region: MLE; cd03318 216591034204 muconate and chloromuconate cycloisomerases; Region: mucon_cyclo; TIGR02534 216591034205 octamer interface [polypeptide binding]; other site 216591034206 active site 216591034207 HMMPfam hit to PF01188, Mandelate racemase / muconate lactonizing en, score 9.9e-92 216591034208 PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 216591034209 HMMPfam hit to PF02746, Mandelate racemase / muconate lactonizing en, score 1.4e-48 216591034210 PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 216591034211 Uncharacterized conserved protein [Function unknown]; Region: COG1359 216591034212 HMMPfam hit to PF03992, Antibiotic biosynthesis monooxygenase, score 2.3e-08 216591034213 1 probable transmembrane helix predicted for BCAS0499 by TMHMM2.0 at aa 12-31 216591034214 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 216591034215 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 216591034216 active site 216591034217 catalytic tetrad [active] 216591034218 HMMPfam hit to PF00248, Aldo/keto reductase family, score 1.7e-75 216591034219 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 216591034220 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591034221 PS00201 Flavodoxin signature. 216591034222 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591034223 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591034224 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591034225 putative effector binding pocket; other site 216591034226 dimerization interface [polypeptide binding]; other site 216591034227 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 9.7e-17 216591034228 Predicted helix-turn-helix motif with score 1403.000, SD 3.97 at aa 20-41, sequence GSFAAAARQLGVTSAAVSKNVA 216591034229 PS00044 Bacterial regulatory proteins, lysR family signature. 216591034230 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.3e-35 216591034231 BcepMu; BcenGI14 216591034232 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 216591034233 HMMPfam hit to PF01757, Acyltransferase family, score 3.6e-20 216591034234 9 probable transmembrane helices predicted for BCAS0504 by TMHMM2.0 at aa 13-35, 40-59, 80-102, 153-175, 182-204, 214-231, 252-274, 300-319 and 332-354 216591034235 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034236 Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684 216591034237 PS00017 ATP/GTP-binding site motif A (P-loop). 216591034238 Baseplate J-like protein; Region: Baseplate_J; cl01294 216591034239 HMMPfam hit to PF04865, Baseplate J-like protein, score 4.6e-108 216591034240 Gene 25-like lysozyme; Region: GPW_gp25; cl01403 216591034241 HMMPfam hit to PF04965, GPW / gp25 family, score 8.3e-35 216591034242 Phage-related baseplate assembly protein; Region: Phage_base_V; cl17812 216591034243 phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644 216591034244 HMMPfam hit to PF04717, Phage-related baseplate assembly protein, score 6.4e-27 216591034245 tail protein; Provisional; Region: D; PHA02561 216591034246 HMMPfam hit to PF05954, Phage late control gene D protein (GPD), score 5.4e-82 216591034247 Phage Tail Protein X; Region: Phage_tail_X; pfam05489 216591034248 HMMPfam hit to PF05489, Phage Tail Protein X, score 3.6e-19 216591034249 Phage P2 GpU; Region: Phage_P2_GpU; pfam06995 216591034250 HMMPfam hit to PF06995, Phage P2 GpU, score 2.6e-14 216591034251 phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760 216591034252 6 probable transmembrane helices predicted for BCAS0513 by TMHMM2.0 at aa 478-500, 536-558, 573-595, 602-624, 629-651 and 658-680 216591034253 Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109 216591034254 Phage tail tube protein FII; Region: Phage_tube; pfam04985 216591034255 HMMPfam hit to PF04985, Phage tail tube protein FII, score 1e-07 216591034256 Phage tail sheath protein; Region: Phage_sheath_1; cl01389 216591034257 major tail sheath protein; Provisional; Region: FI; PHA02560 216591034258 HMMPfam hit to PF04984, Phage tail sheath protein, score 5.1e-163 216591034259 Gp37 protein; Region: Gp37; pfam09646 216591034260 Protein of unknown function (DUF1320); Region: DUF1320; pfam07030 216591034261 HMMPfam hit to PF07030, Protein of unknown function (DUF1320), score 3e-23 216591034262 SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cl00436 216591034263 Phage virion morphogenesis family; Region: Phage_tail_S; cl02089 216591034264 HMMPfam hit to PF05069, Phage virion morphogenesis family, score 3.7e-14 216591034265 Phage Mu protein F like protein; Region: Phage_Mu_F; pfam04233 216591034266 HMMPfam hit to PF04233, Phage Mu protein F like protein, score 1.8e-63 216591034267 Protein of unknown function (DUF935); Region: DUF935; pfam06074 216591034268 Mu-like prophage protein gp29 [Function unknown]; Region: COG4383 216591034269 HMMPfam hit to PF06074, Protein of unknown function (DUF935), score 1.4e-147 216591034270 Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373 216591034271 Protein of unknown function (DUF3486); Region: DUF3486; pfam11985 216591034272 1 probable transmembrane helix predicted for BCAS0531 by TMHMM2.0 at aa 10-32 216591034273 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034274 1 probable transmembrane helix predicted for BCAS0532 by TMHMM2.0 at aa 13-35 216591034275 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591034276 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 216591034277 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591034278 catalytic residue [active] 216591034279 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 2.8e-05 216591034280 Protein of unknown function (DUF4063); Region: DUF4063; pfam13272 216591034281 3 probable transmembrane helices predicted for BCAS0534 by TMHMM2.0 at aa 10-27, 34-52 and 91-113 216591034282 2 probable transmembrane helices predicted for BCAS0536 by TMHMM2.0 at aa 37-54 and 61-83 216591034283 PS00017 ATP/GTP-binding site motif A (P-loop). 216591034284 1 probable transmembrane helix predicted for BCAS0538 by TMHMM2.0 at aa 184-201 216591034285 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 216591034286 sequence-specific DNA binding site [nucleotide binding]; other site 216591034287 salt bridge; other site 216591034288 phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111 216591034289 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 216591034290 dimerization interface [polypeptide binding]; other site 216591034291 putative DNA binding site [nucleotide binding]; other site 216591034292 putative Zn2+ binding site [ion binding]; other site 216591034293 Predicted helix-turn-helix motif with score 1416.000, SD 4.01 at aa 28-49, sequence LTPGELTKATNLSPSNITRYVA 216591034294 Integrase core domain; Region: rve; pfam00665 216591034295 HMMPfam hit to PF00665, Integrase core domain, score 1.2e-07 216591034296 Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]; Region: ExeA; COG3267 216591034297 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189 216591034298 Walker A motif; other site 216591034299 ATP binding site [chemical binding]; other site 216591034300 Walker B motif; other site 216591034301 Predicted helix-turn-helix motif with score 1933.000, SD 5.77 at aa 14-35, sequence IKQAELAEHLNLSQAAVAQIVN 216591034302 PS00017 ATP/GTP-binding site motif A (P-loop). 216591034303 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u5; cd11542 216591034304 metal binding site [ion binding]; metal-binding site 216591034305 Protein of unknown function (DUF3164); Region: DUF3164; pfam11363 216591034306 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 216591034307 IHF dimer interface [polypeptide binding]; other site 216591034308 IHF - DNA interface [nucleotide binding]; other site 216591034309 HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 4.5e-46 216591034310 PS00045 Bacterial histone-like DNA-binding proteins signature. 216591034311 Protein of unknown function (DUF2528); Region: DUF2528; pfam10800 216591034312 Protein of unknown function (DUF1018); Region: DUF1018; pfam06252 216591034313 HMMPfam hit to PF06252, Protein of unknown function (DUF1018), score 2.4e-47 216591034314 Mor transcription activator family; Region: Mor; pfam08765 216591034315 Predicted helix-turn-helix motif with score 1822.000, SD 5.39 at aa 80-101, sequence DNHAELARKFGVSLQWIYKIIK 216591034316 Gene remnant. Similar to the N-terminal 722 residues of Bradyrhizobium japonicum transcriptional regulator TtrR SWALL:Q89V61 (EMBL:AP005939) (946 aa) fasta scores: E(): 4e-58, 36.16% id in 730 aa. CDS is truncated by the insertion of the downstream prophage (BcepMu) and subsequent recombination events 216591034317 HMMPfam hit to PF00486, Transcriptional regulatory protein, C ter, score 4.6e-18 216591034318 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591034319 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591034320 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591034321 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 4.5e-09 216591034322 Predicted helix-turn-helix motif with score 1285.000, SD 3.56 at aa 219-240, sequence VSIEEVANECDLSRGYFIRAFS 216591034323 PS00041 Bacterial regulatory proteins, araC family signature. 216591034324 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.3e-12 216591034325 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 216591034326 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 5.8e-18 216591034327 1 probable transmembrane helix predicted for BCAS0557 by TMHMM2.0 at aa 13-35 216591034328 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591034329 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591034330 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591034331 putative effector binding pocket; other site 216591034332 dimerization interface [polypeptide binding]; other site 216591034333 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.8e-12 216591034334 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.8e-45 216591034335 Domain of unknown function (DUF4104); Region: DUF4104; pfam13372 216591034336 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034337 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 216591034338 DoxX; Region: DoxX; cl17842 216591034339 2 probable transmembrane helices predicted for BCAS0561 by TMHMM2.0 at aa 21-43 and 58-80 216591034340 Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574 216591034341 YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300 216591034342 active site 216591034343 HMMPfam hit to PF07969, Amidohydrolase family, score 5e-144 216591034344 PS00017 ATP/GTP-binding site motif A (P-loop). 216591034345 Protein of unknown function (DUF1427); Region: DUF1427; pfam07235 216591034346 HMMPfam hit to PF07235, Protein of unknown function (DUF1427), score 2.7e-07 216591034347 2 probable transmembrane helices predicted for BCAS0564 by TMHMM2.0 at aa 4-21 and 28-47 216591034348 YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012 216591034349 Isochorismatase family; Region: Isochorismatase; pfam00857 216591034350 catalytic triad [active] 216591034351 dimer interface [polypeptide binding]; other site 216591034352 conserved cis-peptide bond; other site 216591034353 HMMPfam hit to PF00857, Isochorismatase family, score 1.2e-05 216591034354 Protein of unknown function (DUF1427); Region: DUF1427; pfam07235 216591034355 HMMPfam hit to PF07235, Protein of unknown function (DUF1427), score 3.3e-36 216591034356 2 probable transmembrane helices predicted for BCAS0566 by TMHMM2.0 at aa 5-22 and 27-49 216591034357 Probable gene remnant resulting from a deletion event. Similar to the N-terminus of Burkholderia cenocepacia transcriptional regulator, LysR family UniProt:Q1BVG0 (EMBL:CP000378 (302 aa) fasta scores: E()=2.4e-34, 88.793% id in 116 aa. The downstream CDS is similar to the C-terminal region of this protein 216591034358 Probable gene remnant resulting from a deletion event. Similar to Burkholderia cenocepacia transcriptional regulator, LysR family UniProt:Q1BVG0 (EMBL:CP000378 (302 aa) fasta scores: E()=1e-23, 94.030% id in 67 aa. The upstream CDS is similar to the N-terminal region of this protein 216591034359 Protein of unknown function (DUF1275); Region: DUF1275; pfam06912 216591034360 HMMPfam hit to PF06912, Protein of unknown function (DUF1275), score 1.6e-32 216591034361 5 probable transmembrane helices predicted for BCAS0568 by TMHMM2.0 at aa 22-44, 59-81, 101-123, 127-146 and 199-221 216591034362 Protein of unknown function (DUF1427); Region: DUF1427; pfam07235 216591034363 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 216591034364 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.5e-25 216591034365 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591034366 hypothetical protein; Provisional; Region: PRK07236 216591034367 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654 216591034368 HMMPfam hit to PF01494, FAD binding domain, score 8.8e-05 216591034369 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591034370 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 216591034371 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 216591034372 Walker A/P-loop; other site 216591034373 ATP binding site [chemical binding]; other site 216591034374 Q-loop/lid; other site 216591034375 ABC transporter signature motif; other site 216591034376 Walker B; other site 216591034377 D-loop; other site 216591034378 H-loop/switch region; other site 216591034379 HMMPfam hit to PF00005, ABC transporter, score 1.5e-63 216591034380 PS00211 ABC transporters family signature. 216591034381 PS00017 ATP/GTP-binding site motif A (P-loop). 216591034382 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 216591034383 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591034384 dimer interface [polypeptide binding]; other site 216591034385 conserved gate region; other site 216591034386 putative PBP binding loops; other site 216591034387 ABC-ATPase subunit interface; other site 216591034388 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6.7e-14 216591034389 5 probable transmembrane helices predicted for BCAS0575 by TMHMM2.0 at aa 15-37, 57-79, 83-105, 142-164 and 179-201 216591034390 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 216591034391 dimer interface [polypeptide binding]; other site 216591034392 conserved gate region; other site 216591034393 putative PBP binding loops; other site 216591034394 ABC-ATPase subunit interface; other site 216591034395 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6.5e-21 216591034396 5 probable transmembrane helices predicted for BCAS0576 by TMHMM2.0 at aa 23-45, 66-88, 93-112, 158-180 and 190-212 216591034397 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 216591034398 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591034399 substrate binding pocket [chemical binding]; other site 216591034400 membrane-bound complex binding site; other site 216591034401 hinge residues; other site 216591034402 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.2e-45 216591034403 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 216591034404 1 probable transmembrane helix predicted for BCAS0577 by TMHMM2.0 at aa 13-35 216591034405 L-asparagine permease; Provisional; Region: PRK15049 216591034406 HMMPfam hit to PF00324, Amino acid permease, score 2.1e-151 216591034407 11 probable transmembrane helices predicted for BCAS0578 by TMHMM2.0 at aa 56-78, 114-136, 141-163, 176-198, 218-240, 260-282, 297-319, 351-373, 377-399, 420-442 and 447-469 216591034408 PS00218 Amino acid permeases signature. 216591034409 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591034410 PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861 216591034411 putative active site [active] 216591034412 Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002 216591034413 looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439 216591034414 HMMPfam hit to PF04014, SpoVT / AbrB like domain, score 5.6e-08 216591034415 Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841 216591034416 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 1.2e-149 216591034417 10 probable transmembrane helices predicted for BCAS0582 by TMHMM2.0 at aa 13-30, 358-380, 433-455, 460-482, 538-557, 895-917, 924-943, 948-970, 996-1018 and 1031-1053 216591034418 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 216591034419 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591034420 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591034421 1 probable transmembrane helix predicted for BCAS0583 by TMHMM2.0 at aa 43-62 216591034422 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.7e-09 216591034423 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591034424 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034425 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.5e-19 216591034426 PS00017 ATP/GTP-binding site motif A (P-loop). 216591034427 HMMPfam hit to PF02321, Outer membrane efflux protein, score 5.4e-47 216591034428 heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386 216591034429 HAMP domain; Region: HAMP; pfam00672 216591034430 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591034431 dimer interface [polypeptide binding]; other site 216591034432 phosphorylation site [posttranslational modification] 216591034433 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591034434 ATP binding site [chemical binding]; other site 216591034435 Mg2+ binding site [ion binding]; other site 216591034436 G-X-G motif; other site 216591034437 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.3e-35 216591034438 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.7e-19 216591034439 HMMPfam hit to PF00672, HAMP domain, score 6.6e-10 216591034440 2 probable transmembrane helices predicted for BCAS0585 by TMHMM2.0 at aa 10-32 and 190-207 216591034441 heavy metal response regulator; Region: cztR_silR_copR; TIGR01387 216591034442 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591034443 active site 216591034444 phosphorylation site [posttranslational modification] 216591034445 intermolecular recognition site; other site 216591034446 dimerization interface [polypeptide binding]; other site 216591034447 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591034448 DNA binding site [nucleotide binding] 216591034449 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 4.4e-23 216591034450 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.8e-39 216591034451 Truncation of N terminal 235 amino acids; frameshift after codon 66 216591034452 20 amino acid section similar to residues 338-362 Pseudomonas fluorescens halogenase PrnC prnC SWALL:P95482 (EMBL:U74493) (567 aa) fasta scores: E(): 2.1e-06, 88% id in 25 aa; truncation of N terminal 337 amino acids, truncation of C terminal 104 amino acids 216591034453 Similar to Ralstonia solanacearum probable transmembrane protein rs03653 SWALL:Q8XXM5 (EMBL:AL646068) (200 aa) fasta scores: E(): 1.2e-22, 71.27% id in 94 aa; N terminus only. Truncation of C-terminal 104 amino acids; frameshift after codon 50 216591034454 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 216591034455 HAMP domain; Region: HAMP; pfam00672 216591034456 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591034457 dimer interface [polypeptide binding]; other site 216591034458 phosphorylation site [posttranslational modification] 216591034459 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591034460 ATP binding site [chemical binding]; other site 216591034461 Mg2+ binding site [ion binding]; other site 216591034462 G-X-G motif; other site 216591034463 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.5e-30 216591034464 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.6e-10 216591034465 HMMPfam hit to PF00672, HAMP domain, score 1.1e-09 216591034466 2 probable transmembrane helices predicted for BCAS0589 by TMHMM2.0 at aa 5-24 and 132-154 216591034467 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591034468 active site 216591034469 phosphorylation site [posttranslational modification] 216591034470 intermolecular recognition site; other site 216591034471 dimerization interface [polypeptide binding]; other site 216591034472 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591034473 DNA binding site [nucleotide binding] 216591034474 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 2.5e-19 216591034475 HMMPfam hit to PF00072, Response regulator receiver domain, score 4.3e-32 216591034476 multidrug efflux system protein MdtE; Provisional; Region: PRK09859 216591034477 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591034478 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591034479 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034480 HMMPfam hit to PF00529, HlyD family secretion protein, score 2.9e-69 216591034481 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915 216591034482 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 216591034483 12 probable transmembrane helices predicted for BCAS0592 by TMHMM2.0 at aa 13-35, 340-359, 366-388, 392-414, 438-460, 475-497, 539-561, 889-908, 915-932, 942-964, 990-1012 and 1022-1044 216591034484 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591034485 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034486 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.1e-33 216591034487 HMMPfam hit to PF02321, Outer membrane efflux protein, score 4.2e-51 216591034488 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 216591034489 Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174 216591034490 substrate binding site [chemical binding]; other site 216591034491 dimer interface [polypeptide binding]; other site 216591034492 ATP binding site [chemical binding]; other site 216591034493 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 4e-65 216591034494 PS00583 pfkB family of carbohydrate kinases signature 1. 216591034495 Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738 216591034496 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591034497 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591034498 12 probable transmembrane helices predicted for BCAS0595 by TMHMM2.0 at aa 13-35, 58-80, 87-109, 114-136, 156-173, 208-227, 255-277, 290-312, 321-338, 342-364, 376-398 and 408-425 216591034499 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.5e-22 216591034500 deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269 216591034501 active site 216591034502 catalytic residues [active] 216591034503 DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681 216591034504 DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531 216591034505 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 216591034506 HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 2.3e-49 216591034507 HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 0.00012 216591034508 Predicted helix-turn-helix motif with score 2117.000, SD 6.40 at aa 22-43, sequence IHLKEVAELFGVSEMTIRRDLA 216591034509 PS00894 Bacterial regulatory proteins, deoR family signature. 216591034510 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959 216591034511 intersubunit interface [polypeptide binding]; other site 216591034512 active site 216591034513 catalytic residue [active] 216591034514 HMMPfam hit to PF01791, DeoC/LacD family aldolase, score 4.5e-78 216591034515 Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; pfam05721 216591034516 HMMPfam hit to PF05721, Phytanoyl-CoA dioxygenase (PhyH), score 2e-19 216591034517 Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG2607 216591034518 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591034519 Walker A motif; other site 216591034520 ATP binding site [chemical binding]; other site 216591034521 Walker B motif; other site 216591034522 HMMPfam hit to PF05673, Protein of unknown function (DUF815), score 2.5e-48 216591034523 PS00017 ATP/GTP-binding site motif A (P-loop). 216591034524 EamA-like transporter family; Region: EamA; pfam00892 216591034525 Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950 216591034526 EamA-like transporter family; Region: EamA; pfam00892 216591034527 10 probable transmembrane helices predicted for BCAS0602 by TMHMM2.0 at aa 5-22, 35-57, 61-80, 93-115, 119-138, 150-172, 182-204, 216-238, 248-266 and 271-290 216591034528 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.7e-15 216591034529 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.2e-21 216591034530 Cupin domain; Region: Cupin_2; cl17218 216591034531 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591034532 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591034533 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591034534 HMMPfam hit to PF07883, Cupin domain, score 0.0043 216591034535 Predicted helix-turn-helix motif with score 2234.000, SD 6.80 at aa 184-205, sequence RTIAEWADLLGLSVRTLHRAFR 216591034536 PS00041 Bacterial regulatory proteins, araC family signature. 216591034537 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.4e-07 216591034538 Domain of unknown function (DUF1772); Region: DUF1772; cl12097 216591034539 4 probable transmembrane helices predicted for BCAS0604 by TMHMM2.0 at aa 9-31, 57-79, 86-108 and 141-160 216591034540 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034541 NADH(P)-binding; Region: NAD_binding_10; pfam13460 216591034542 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591034543 NAD(P) binding site [chemical binding]; other site 216591034544 active site 216591034545 HMMPfam hit to PF05368, NmrA-like family, score 0.0013 216591034546 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591034547 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591034548 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 9.8e-12 216591034549 Predicted helix-turn-helix motif with score 1311.000, SD 3.65 at aa 55-76, sequence FRMSDIVERTGISFGSLYQYFP 216591034550 3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808 216591034551 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 216591034552 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 216591034553 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 3.3e-54 216591034554 PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 216591034555 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD binding, score 1.8e-92 216591034556 beta-ketothiolase; Provisional; Region: PRK09051 216591034557 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 216591034558 dimer interface [polypeptide binding]; other site 216591034559 active site 216591034560 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 6.1e-69 216591034561 PS00099 Thiolases active site. 216591034562 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 1.8e-129 216591034563 PS00455 Putative AMP-binding domain signature. 216591034564 PS00098 Thiolases acyl-enzyme intermediate signature. 216591034565 Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644 216591034566 hydroxyglutarate oxidase; Provisional; Region: PRK11728 216591034567 Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187 216591034568 Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440 216591034569 HMMPfam hit to PF05187, Electron transfer flavoprotein-ubiquinone ox, score 1e-115 216591034570 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00011 216591034571 acyl-CoA dehydrogenase; Provisional; Region: PTZ00456 216591034572 Acyl-CoA dehydrogenase N terminal; Region: AcylCoA_DH_N; pfam12418 216591034573 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 216591034574 active site 216591034575 Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806 216591034576 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 7.8e-31 216591034577 HMMPfam hit to PF08028, Acyl-CoA dehydrogenase, C-terminal doma, score 4.7e-05 216591034578 HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 7e-18 216591034579 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591034580 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591034581 Helix-turn-helix domain; Region: HTH_28; pfam13518 216591034582 HMMPfam hit to PF01527, Transposase, score 0.0012 216591034583 Predicted helix-turn-helix motif with score 1296.000, SD 3.60 at aa 21-42, sequence AGTKTLAHRYGVGRTMVRRWVA 216591034584 HMMPfam hit to PF02178, AT hook motif, score 0.042 216591034585 putative transposase OrfB; Reviewed; Region: PHA02517 216591034586 HTH-like domain; Region: HTH_21; pfam13276 216591034587 Integrase core domain; Region: rve; pfam00665 216591034588 Integrase core domain; Region: rve_2; pfam13333 216591034589 PS00228 Tubulin-beta mRNA autoregulation signal. 216591034590 Predicted helix-turn-helix motif with score 1108.000, SD 2.96 at aa 8-29, sequence HPVAALLKAAGLARSTFYYQLK 216591034591 HMMPfam hit to PF00665, Integrase core domain, score 3.8e-47 216591034592 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 216591034593 PS00041 Bacterial regulatory proteins, araC family signature. 216591034594 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.0012 216591034595 hypothetical protein; Provisional; Region: PRK07236 216591034596 HMMPfam hit to PF01494, FAD binding domain, score 7.3e-06 216591034597 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 216591034598 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591034599 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591034600 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.4e-08 216591034601 Predicted helix-turn-helix motif with score 1402.000, SD 3.96 at aa 264-285, sequence PVIDQAAEHLHCSVRTLSRHLA 216591034602 Long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07059 216591034603 Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936 216591034604 acyl-activating enzyme (AAE) consensus motif; other site 216591034605 putative AMP binding site [chemical binding]; other site 216591034606 putative active site [active] 216591034607 putative CoA binding site [chemical binding]; other site 216591034608 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.7e-122 216591034609 PS00455 Putative AMP-binding domain signature. 216591034610 1 probable transmembrane helix predicted for BCAS0616 by TMHMM2.0 at aa 77-99 216591034611 HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484 216591034612 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915 216591034613 active site 216591034614 motif I; other site 216591034615 motif II; other site 216591034616 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 216591034617 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591034618 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591034619 Predicted helix-turn-helix motif with score 1148.000, SD 3.10 at aa 277-298, sequence PDIDAIAEILCMTSRTLRRKLE 216591034620 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 7.8e-08 216591034621 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591034622 dimer interface [polypeptide binding]; other site 216591034623 phosphorylation site [posttranslational modification] 216591034624 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591034625 ATP binding site [chemical binding]; other site 216591034626 Mg2+ binding site [ion binding]; other site 216591034627 G-X-G motif; other site 216591034628 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2.4e-24 216591034629 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 6.1e-17 216591034630 HMMPfam hit to PF00672, HAMP domain, score 6.9e-10 216591034631 2 probable transmembrane helices predicted for BCAS0619 by TMHMM2.0 at aa 10-27 and 180-202 216591034632 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034633 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 216591034634 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591034635 active site 216591034636 phosphorylation site [posttranslational modification] 216591034637 intermolecular recognition site; other site 216591034638 dimerization interface [polypeptide binding]; other site 216591034639 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 216591034640 DNA binding site [nucleotide binding] 216591034641 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 2.2e-27 216591034642 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.4e-30 216591034643 1 probable transmembrane helix predicted for BCAS0621 by TMHMM2.0 at aa 5-24 216591034644 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034645 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591034646 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591034647 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591034648 dimerization interface [polypeptide binding]; other site 216591034649 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.4e-28 216591034650 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.3e-22 216591034651 Predicted helix-turn-helix motif with score 1576.000, SD 4.55 at aa 21-42, sequence GSLAGAARRLGISHATVFRRLA 216591034652 Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525 216591034653 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 216591034654 HMMPfam hit to PF02525, Flavodoxin-like fold, score 2e-52 216591034655 Avidin family; Region: Avidin; pfam01382 216591034656 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034657 Protein of unknown function (DUF3897); Region: DUF3897; cl17494 216591034658 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034659 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 216591034660 Sel1-like repeats; Region: SEL1; smart00671 216591034661 HMMPfam hit to PF08238, Sel1 repeat, score 0.018 216591034662 HMMPfam hit to PF08238, Sel1 repeat, score 1.1e-09 216591034663 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034664 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591034665 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591034666 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.1e-12 216591034667 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034668 Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914 216591034669 Natural resistance-associated macrophage protein; Region: Nramp; pfam01566 216591034670 HMMPfam hit to PF01566, Natural resistance-associated macrophage pro, score 6.4e-08 216591034671 10 probable transmembrane helices predicted for BCAS0630 by TMHMM2.0 at aa 51-73, 94-116, 131-150, 157-179, 194-216, 254-276, 296-318, 339-361, 371-393 and 406-428 216591034672 CheB methylesterase; Region: CheB_methylest; pfam01339 216591034673 HMMPfam hit to PF01339, CheB methylesterase, score 4.5e-23 216591034674 CheB methylesterase; Region: CheB_methylest; pfam01339 216591034675 Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352 216591034676 CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705 216591034677 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 216591034678 S-adenosylmethionine binding site [chemical binding]; other site 216591034679 PAS domain; Region: PAS_9; pfam13426 216591034680 PAS domain; Region: PAS_10; pfam13596 216591034681 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 216591034682 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591034683 putative active site [active] 216591034684 heme pocket [chemical binding]; other site 216591034685 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591034686 dimer interface [polypeptide binding]; other site 216591034687 phosphorylation site [posttranslational modification] 216591034688 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591034689 ATP binding site [chemical binding]; other site 216591034690 Mg2+ binding site [ion binding]; other site 216591034691 G-X-G motif; other site 216591034692 Response regulator receiver domain; Region: Response_reg; pfam00072 216591034693 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591034694 active site 216591034695 phosphorylation site [posttranslational modification] 216591034696 intermolecular recognition site; other site 216591034697 dimerization interface [polypeptide binding]; other site 216591034698 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.2e-30 216591034699 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and, score 7.2e-37 216591034700 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.3e-14 216591034701 HMMPfam hit to PF08448, PAS fold, score 0.0004 216591034702 HMMPfam hit to PF08447, PAS fold, score 0.00099 216591034703 HMMPfam hit to PF00989, PAS fold, score 6.2e-09 216591034704 HMMPfam hit to PF00989, PAS fold, score 0.0058 216591034705 HMMPfam hit to PF01739, CheR methyltransferase, SAM binding do, score 7.5e-72 216591034706 PS00092 N-6 Adenine-specific DNA methylases signature. 216591034707 HMMPfam hit to PF03705, CheR methyltransferase, all-alpha doma, score 5.1e-07 216591034708 HMMPfam hit to PF01339, CheB methylesterase, score 1.2e-10 216591034709 Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845 216591034710 Natural resistance-associated macrophage protein; Region: Nramp; pfam01566 216591034711 11 probable transmembrane helices predicted for BCAS0634 by TMHMM2.0 at aa 27-46, 61-79, 100-119, 134-156, 168-190, 210-232, 256-278, 298-320, 333-355, 365-387 and 408-430 216591034712 HMMPfam hit to PF01566, Natural resistance-associated macrophage pro, score 2.4e-117 216591034713 Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051 216591034714 dimanganese center [ion binding]; other site 216591034715 HMMPfam hit to PF05067, Manganese containing catalase, score 8.4e-104 216591034716 chaperonin GroEL; Reviewed; Region: groEL; PRK12849 216591034717 GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344 216591034718 ring oligomerisation interface [polypeptide binding]; other site 216591034719 ATP/Mg binding site [chemical binding]; other site 216591034720 stacking interactions; other site 216591034721 hinge regions; other site 216591034722 HMMPfam hit to PF00118, TCP-1/cpn60 chaperonin family, score 2.8e-196 216591034723 PS00296 Chaperonins cpn60 signature. 216591034724 Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320 216591034725 oligomerisation interface [polypeptide binding]; other site 216591034726 mobile loop; other site 216591034727 roof hairpin; other site 216591034728 HMMPfam hit to PF00166, Chaperonin 10 Kd subunit, score 5.3e-47 216591034729 PS00681 Chaperonins cpn10 signature. 216591034730 PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397 216591034731 Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671 216591034732 active site 216591034733 HMMPfam hit to PF01569, PAP2 superfamily, score 3.3e-08 216591034734 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034735 Similar to C-terminal 105 amino acids of D-(-)-3-hydroxybutyrate oligomer hydrolase; truncation of N terminal 636 amino acids; frameshift after codon 57 216591034736 Similar to Pseudomonas aeruginosa probable short-chain dehydrogenase SWALL:Q9I3W5 (EMBL:AE004567) (277 aa) fasta scores: E(): 2.4e-20, 43.11% id in 225 aa; homology doesn't extend to 45 amino acids at C terminus; frameshifts after codons 18 and 52 216591034737 HMMPfam hit to PF00106, short chain dehydrogenase, score 9.7e-07 216591034738 Frameshifts after codons 27, 127 and 145 216591034739 HMMPfam hit to PF00106, short chain dehydrogenase, score 8.5e-16 216591034740 Frameshift after codon 170 216591034741 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.8e-15 216591034742 HMMPfam hit to PF03466, LysR substrate binding domain, score 9.4e-31 216591034743 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 216591034744 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 216591034745 non-specific DNA binding site [nucleotide binding]; other site 216591034746 salt bridge; other site 216591034747 sequence-specific DNA binding site [nucleotide binding]; other site 216591034748 Predicted helix-turn-helix motif with score 1194.000, SD 3.25 at aa 17-38, sequence LTQPEFAELGGVHKQAQFHYER 216591034749 Phytoreovirus nonstructural protein Pns10/11; Region: Phytoreo_Pns; pfam05451 216591034750 IS2 transposase TnpB; Reviewed; Region: PRK09409 216591034751 HTH-like domain; Region: HTH_21; pfam13276 216591034752 Integrase core domain; Region: rve; pfam00665 216591034753 Integrase core domain; Region: rve_3; pfam13683 216591034754 HMMPfam hit to PF00665, Integrase core domain, score 2.2e-28 216591034755 Similar to C-terminus Ralstonia solanacearum ISRso10-transposase OrfA protein tisrso10A SWALL:Q8XWY6 (EMBL:AL646069) (88 aa) fasta scores: E(): 2e-10, 90.62% id in 32 aa; homology only extends to 57 C-terminal amino acids. Truncation of N-terminal 56 amino acids 216591034756 Truncation of N-terminal 294 amino acids. Similar to Alcaligenes eutrophus putative transposase tnpA SWALL:Q7WWT0 (EMBL:AY305378) (339 aa) fasta scores: E(): 3.5e-07, 70.27% id in 37 aa 216591034757 HMMPfam hit to PF01527, Transposase, score 6.7e-38 216591034758 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591034759 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591034760 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591034761 HMMPfam hit to PF01548, Transposase, score 0.0011 216591034762 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 1.2e-35 216591034763 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584 216591034764 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 216591034765 DNA-binding interface [nucleotide binding]; DNA binding site 216591034766 Integrase core domain; Region: rve; pfam00665 216591034767 HMMPfam hit to PF02796, Helix-turn-helix domain of resolvase, score 0.0028 216591034768 Predicted helix-turn-helix motif with score 2020.000, SD 6.07 at aa 18-39, sequence VSEREIARRLGISRNTVARYLS 216591034769 HMMPfam hit to PF00665, Integrase core domain, score 2.7e-25 216591034770 transposase/IS protein; Provisional; Region: PRK09183 216591034771 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 216591034772 Walker A motif; other site 216591034773 ATP binding site [chemical binding]; other site 216591034774 Walker B motif; other site 216591034775 HMMPfam hit to PF01695, IstB-like ATP binding protein, score 9.6e-88 216591034776 PS00017 ATP/GTP-binding site motif A (P-loop). 216591034777 IS2 transposase TnpB; Reviewed; Region: PRK09409 216591034778 HTH-like domain; Region: HTH_21; pfam13276 216591034779 Integrase core domain; Region: rve; pfam00665 216591034780 Integrase core domain; Region: rve_3; pfam13683 216591034781 Predicted helix-turn-helix motif with score 1005.000, SD 2.61 at aa 12-33, sequence RPVKLVCEVLGVSRSNVSARLS 216591034782 HMMPfam hit to PF00665, Integrase core domain, score 7.4e-29 216591034783 Similar to N terminus of IncL/M plasmid R471a RetA retA SWALL:O52209 (EMBL:AF027768) (495 aa) fasta scores: E(): 2.1e-76, 62.21% id in 307 aa; C terminal 175 amino acids truncated 216591034784 Group II intron - EBS1 216591034785 Group II intron - EBS2 216591034786 truncation of C terminal 13 amino acids 216591034787 HMMPfam hit to PF05717, IS66 Orf2 like protein, score 1.7e-54 216591034788 Group II intron - IBS1 216591034789 Group II intron - IBS2 216591034790 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 216591034791 Transposase; Region: HTH_Tnp_1; pfam01527 216591034792 HMMPfam hit to PF01527, Transposase, score 3.1e-07 216591034793 H-NS histone family; Region: Histone_HNS; pfam00816 216591034794 Domain in histone-like proteins of HNS family; Region: HNS; smart00528 216591034795 HMMPfam hit to PF00816, H-NS histone family, score 8.1e-19 216591034796 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 216591034797 Protein of unknown function (Gmx_para_CXXCG); Region: Gmx_para_CXXCG; cl15282 216591034798 SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346 216591034799 PAAR motif; Region: PAAR_motif; pfam05488 216591034800 RHS Repeat; Region: RHS_repeat; cl11982 216591034801 RHS Repeat; Region: RHS_repeat; pfam05593 216591034802 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 216591034803 RHS Repeat; Region: RHS_repeat; pfam05593 216591034804 RHS Repeat; Region: RHS_repeat; cl11982 216591034805 RHS Repeat; Region: RHS_repeat; cl11982 216591034806 RHS protein; Region: RHS; pfam03527 216591034807 RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696 216591034808 A nuclease of the HNH/ENDO VII superfamily with conserved WHH; Region: WHH; pfam14414 216591034809 HMMPfam hit to PF03527, RHS protein, score 9.1e-07 216591034810 HMMPfam hit to PF05593, RHS Repeat, score 0.00025 216591034811 HMMPfam hit to PF05593, RHS Repeat, score 1.1 216591034812 HMMPfam hit to PF05593, RHS Repeat, score 4.6e-06 216591034813 HMMPfam hit to PF05593, RHS Repeat, score 0.03 216591034814 HMMPfam hit to PF05593, RHS Repeat, score 0.0071 216591034815 HMMPfam hit to PF05593, RHS Repeat, score 0.00012 216591034816 PS00216 Sugar transport proteins signature 1. 216591034817 HMMPfam hit to PF05593, RHS Repeat, score 0.8 216591034818 HMMPfam hit to PF05593, RHS Repeat, score 0.014 216591034819 HMMPfam hit to PF05593, RHS Repeat, score 0.32 216591034820 HMMPfam hit to PF05593, RHS Repeat, score 7.7e-05 216591034821 HMMPfam hit to PF05593, RHS Repeat, score 0.11 216591034822 HMMPfam hit to PF05593, RHS Repeat, score 0.0027 216591034823 HMMPfam hit to PF05488, PAAR motif, score 2.2e-09 216591034824 HMMPfam hit to PF05488, PAAR motif, score 5.3e-05 216591034825 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034826 2 probable transmembrane helices predicted for BCAS0663 by TMHMM2.0 at aa 15-37 and 42-64 216591034827 Domain of unknown function (DUF1795); Region: DUF1795; pfam08786 216591034828 4 probable transmembrane helices predicted for BCAS0665 by TMHMM2.0 at aa 16-35, 50-72, 85-104 and 114-136 216591034829 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034830 ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204 216591034831 Ankyrin repeats (3 copies); Region: Ank_2; pfam12796 216591034832 Ankyrin repeats (many copies); Region: Ank_4; pfam13637 216591034833 HMMPfam hit to PF00023, Ankyrin repeat, score 0.0046 216591034834 PS00017 ATP/GTP-binding site motif A (P-loop). 216591034835 HMMPfam hit to PF00023, Ankyrin repeat, score 0.00021 216591034836 HMMPfam hit to PF00023, Ankyrin repeat, score 2.1 216591034837 1 probable transmembrane helix predicted for BCAS0666 by TMHMM2.0 at aa 7-26 216591034838 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 216591034839 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 216591034840 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 216591034841 PS00120 Lipases, serine active site. 216591034842 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 2.4e-38 216591034843 Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3519 216591034844 Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947 216591034845 HMMPfam hit to PF05947, Bacterial protein of unknown function (DUF87, score 3.2e-78 216591034846 Lecithin retinol acyltransferase; Region: LRAT; pfam04970 216591034847 2 probable transmembrane helices predicted for BCAS0671 by TMHMM2.0 at aa 189-211 and 216-238 216591034848 RES domain; Region: RES; cl02411 216591034849 TniQ; Region: TniQ; pfam06527 216591034850 Bacterial TniB protein; Region: TniB; pfam05621 216591034851 AAA domain; Region: AAA_22; pfam13401 216591034852 HMMPfam hit to PF05621, Bacterial TniB protein, score 7.4e-61 216591034853 PS00017 ATP/GTP-binding site motif A (P-loop). 216591034854 HMMPfam hit to PF00665, Integrase core domain, score 3.1e-19 216591034855 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 216591034856 Transposase; Region: DEDD_Tnp_IS110; pfam01548 216591034857 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 216591034858 HMMPfam hit to PF01548, Transposase, score 0.001 216591034859 HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 1.5e-42 216591034860 N-terminus truncated by 289 amino acids. Frameshift after codon 130 216591034861 6 probable transmembrane helices predicted for BCAS0687 by TMHMM2.0 at aa 20-37, 80-102, 115-137, 142-161, 170-192 and 207-229 216591034862 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591034863 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 216591034864 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591034865 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.2e-06 216591034866 Predicted helix-turn-helix motif with score 1135.000, SD 3.05 at aa 28-49, sequence TSLQQLEQATGVNKSGLYSEFE 216591034867 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 216591034868 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 6.3e-12 216591034869 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 216591034870 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591034871 putative substrate translocation pore; other site 216591034872 12 probable transmembrane helices predicted for BCAS0690 by TMHMM2.0 at aa 12-34, 49-71, 78-97, 102-124, 137-159, 164-186, 212-234, 244-263, 270-292, 297-319, 332-354 and 359-381 216591034873 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.1e-31 216591034874 LrgA family; Region: LrgA; pfam03788 216591034875 HMMPfam hit to PF03788, LrgA family, score 4.3e-20 216591034876 3 probable transmembrane helices predicted for BCAS0691 by TMHMM2.0 at aa 20-42, 57-76 and 83-105 216591034877 LrgB-like family; Region: LrgB; cl00596 216591034878 6 probable transmembrane helices predicted for BCAS0692 by TMHMM2.0 at aa 5-27, 40-62, 67-89, 102-121, 156-178 and 214-236 216591034879 HMMPfam hit to PF04172, LrgB-like family, score 3.1e-61 216591034880 Uncharacterized conserved protein [Function unknown]; Region: COG1359 216591034881 HMMPfam hit to PF03992, Antibiotic biosynthesis monooxygenase, score 2.2e-17 216591034882 uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926 216591034883 Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627 216591034884 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 1.7e-07 216591034885 BON domain; Region: BON; pfam04972 216591034886 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 0.00011 216591034887 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591034888 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591034889 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591034890 putative effector binding pocket; other site 216591034891 dimerization interface [polypeptide binding]; other site 216591034892 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.5e-37 216591034893 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.6e-15 216591034894 Predicted helix-turn-helix motif with score 1148.000, SD 3.10 at aa 17-38, sequence GSFSSAAREADLLPGQVSAAIQ 216591034895 Arginate lyase and other MDR family members; Region: AL_MDR; cd08252 216591034896 zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817 216591034897 putative NAD(P) binding site [chemical binding]; other site 216591034898 dimer interface [polypeptide binding]; other site 216591034899 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 4.2e-19 216591034900 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 5.4e-11 216591034901 PS01162 Quinone oxidoreductase / zeta-crystallin signature. 216591034902 Major royal jelly protein; Region: MRJP; pfam03022 216591034903 1 probable transmembrane helix predicted for BCAS0699 by TMHMM2.0 at aa 13-35 216591034904 HMMPfam hit to PF03022, Major royal jelly protein, score 3.8e-20 216591034905 NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149 216591034906 dimer interface [polypeptide binding]; other site 216591034907 FMN binding site [chemical binding]; other site 216591034908 HMMPfam hit to PF00881, Nitroreductase family, score 9.7e-46 216591034909 1 probable transmembrane helix predicted for BCAS0700 by TMHMM2.0 at aa 143-162 216591034910 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 216591034911 EamA-like transporter family; Region: EamA; pfam00892 216591034912 10 probable transmembrane helices predicted for BCAS0701 by TMHMM2.0 at aa 21-38, 48-70, 83-105, 115-132, 139-157, 167-189, 196-218, 228-250, 257-279 and 283-305 216591034913 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.2e-19 216591034914 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 0.00074 216591034915 Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069 216591034916 ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891 216591034917 HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 8.9e-28 216591034918 Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300 216591034919 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591034920 NAD(P) binding site [chemical binding]; other site 216591034921 active site 216591034922 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.2e-29 216591034923 PS00061 Short-chain dehydrogenases/reductases family signature. 216591034924 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 216591034925 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltE; COG3967 216591034926 NAD(P) binding site [chemical binding]; other site 216591034927 active site 216591034928 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.2e-27 216591034929 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00037 216591034930 PS00061 Short-chain dehydrogenases/reductases family signature. 216591034931 mercuric reductase; Validated; Region: PRK06370 216591034932 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 216591034933 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 216591034934 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 3e-34 216591034935 PS00017 ATP/GTP-binding site motif A (P-loop). 216591034936 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 4.7e-27 216591034937 HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 5.8e-32 216591034938 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 216591034939 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 216591034940 putative substrate translocation pore; other site 216591034941 12 probable transmembrane helices predicted for BCAS0706 by TMHMM2.0 at aa 32-51, 66-88, 101-120, 125-147, 159-181, 191-213, 257-279, 294-313, 325-344, 348-370, 382-404 and 414-436 216591034942 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5e-48 216591034943 Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566 216591034944 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591034945 active site 216591034946 phosphorylation site [posttranslational modification] 216591034947 intermolecular recognition site; other site 216591034948 dimerization interface [polypeptide binding]; other site 216591034949 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 216591034950 DNA binding residues [nucleotide binding] 216591034951 dimerization interface [polypeptide binding]; other site 216591034952 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 5.6e-21 216591034953 HMMPfam hit to PF08281, Sigma-70, region, score 1.8e-07 216591034954 PS00622 Bacterial regulatory proteins, luxR family signature. 216591034955 HMMPfam hit to PF00072, Response regulator receiver domain, score 6.5e-27 216591034956 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591034957 nitrogen fixation negative regulator NifL; Region: nifL_nitrog; TIGR02938 216591034958 putative active site [active] 216591034959 heme pocket [chemical binding]; other site 216591034960 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 216591034961 putative active site [active] 216591034962 heme pocket [chemical binding]; other site 216591034963 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 216591034964 dimer interface [polypeptide binding]; other site 216591034965 phosphorylation site [posttranslational modification] 216591034966 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 216591034967 ATP binding site [chemical binding]; other site 216591034968 Mg2+ binding site [ion binding]; other site 216591034969 G-X-G motif; other site 216591034970 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5.8e-33 216591034971 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.1e-11 216591034972 HMMPfam hit to PF08448, PAS fold, score 6.2e-05 216591034973 HMMPfam hit to PF08447, PAS fold, score 1.7e-15 216591034974 HMMPfam hit to PF00989, PAS fold, score 1.6e-05 216591034975 PS00037 Myb DNA-binding domain repeat signature 1. 216591034976 HMMPfam hit to PF08448, PAS fold, score 5.9e-08 216591034977 HMMPfam hit to PF08447, PAS fold, score 9.4e-08 216591034978 HMMPfam hit to PF00989, PAS fold, score 1.5e-07 216591034979 3 probable transmembrane helices predicted for BCAS0708 by TMHMM2.0 at aa 45-67, 77-108 and 115-137 216591034980 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 216591034981 Response regulator receiver domain; Region: Response_reg; pfam00072 216591034982 active site 216591034983 phosphorylation site [posttranslational modification] 216591034984 intermolecular recognition site; other site 216591034985 dimerization interface [polypeptide binding]; other site 216591034986 HMMPfam hit to PF00072, Response regulator receiver domain, score 9.6e-24 216591034987 transcriptional regulator; Provisional; Region: PRK10632 216591034988 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591034989 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591034990 dimerization interface [polypeptide binding]; other site 216591034991 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.6e-35 216591034992 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.9e-17 216591034993 PS00044 Bacterial regulatory proteins, lysR family signature. 216591034994 Predicted helix-turn-helix motif with score 1281.000, SD 3.55 at aa 18-39, sequence GSFTAAADMLGISAASASTLVR 216591034995 2-oxoacid dehydrogenase subunit E1; Provisional; Region: PRK13012 216591034996 Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017 216591034997 dimer interface [polypeptide binding]; other site 216591034998 TPP-binding site [chemical binding]; other site 216591034999 Transketolase, pyrimidine binding domain; Region: Transket_pyr; smart00861 216591035000 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 216591035001 AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404 216591035002 putative DNA binding site [nucleotide binding]; other site 216591035003 putative Zn2+ binding site [ion binding]; other site 216591035004 AsnC family; Region: AsnC_trans_reg; pfam01037 216591035005 Predicted helix-turn-helix motif with score 975.000, SD 2.51 at aa 29-50, sequence ITNAELARAVNLSSTPCFNRVR 216591035006 PS00519 Bacterial regulatory proteins, asnC family signature. 216591035007 HMMPfam hit to PF01037, AsnC family, score 2.8e-34 216591035008 short chain dehydrogenase; Provisional; Region: PRK06482 216591035009 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374 216591035010 NADP binding site [chemical binding]; other site 216591035011 active site 216591035012 steroid binding site; other site 216591035013 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0017 216591035014 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.8e-18 216591035015 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591035016 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591035017 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474 216591035018 putative effector binding pocket; other site 216591035019 putative dimerization interface [polypeptide binding]; other site 216591035020 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.3e-20 216591035021 Predicted helix-turn-helix motif with score 1359.000, SD 3.82 at aa 20-41, sequence RSFRKAAEELELAASTLSHMMR 216591035022 PS00044 Bacterial regulatory proteins, lysR family signature. 216591035023 HMMPfam hit to PF03466, LysR substrate binding domain, score 7.8e-52 216591035024 Restriction endonuclease; Region: Mrr_cat; pfam04471 216591035025 HMMPfam hit to PF04471, Restriction endonuclease, score 1.8e-11 216591035026 AAA ATPase domain; Region: AAA_16; pfam13191 216591035027 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035028 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035029 Transposase; Region: HTH_Tnp_1; pfam01527 216591035030 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591035031 CDS lacks appropriate translational start site. It is likely that this CDS encodes the C-terminal region of a larger protein encompassing the upstream CDS. A translational frameshift possibly occurs after residue 86 of the upstream overlapping CDS 216591035032 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591035033 truncated by IS element insertion after codon 325 216591035034 Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400 216591035035 active site 216591035036 NTP binding site [chemical binding]; other site 216591035037 metal binding triad [ion binding]; metal-binding site 216591035038 Patatin-like phospholipase; includes PNPLA8, PNPLA9, and Pat17; Region: Pat17_PNPLA8_PNPLA9_like; cd07199 216591035039 active site 216591035040 nucleophile elbow; other site 216591035041 HMMPfam hit to PF01734, Patatin-like phospholipase, score 2.3e-32 216591035042 Protein of unknown function (DUF1016); Region: DUF1016; pfam06250 216591035043 Predicted nuclease of restriction endonuclease-like fold [General function prediction only]; Region: COG4804 216591035044 HMMPfam hit to PF06250, Protein of unknown function (DUF1016), score 7e-179 216591035045 methionine sulfoxide reductase B; Provisional; Region: PRK00222 216591035046 SelR domain; Region: SelR; pfam01641 216591035047 1 probable transmembrane helix predicted for BCAS0724 by TMHMM2.0 at aa 7-24 216591035048 HMMPfam hit to PF01641, SelR domain, score 1.9e-68 216591035049 Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785 216591035050 Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788 216591035051 TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA...; Region: TlpA_like_DipZ_like; cd03012 216591035052 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 216591035053 catalytic residues [active] 216591035054 5 probable transmembrane helices predicted for BCAS0725 by TMHMM2.0 at aa 5-27, 42-64, 73-92, 123-145 and 158-180 216591035055 HMMPfam hit to PF02683, Cytochrome C biogenesis protein transmembran, score 1e-07 216591035056 HMMPfam hit to PF08534, Redoxin, score 4.6e-05 216591035057 methionine sulfoxide reductase A; Provisional; Region: PRK13014 216591035058 1 probable transmembrane helix predicted for BCAS0726 by TMHMM2.0 at aa 21-38 216591035059 HMMPfam hit to PF01625, Peptide methionine sulfoxide reductase, score 2.4e-75 216591035060 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 216591035061 Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469 216591035062 [2Fe-2S] cluster binding site [ion binding]; other site 216591035063 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 6.2e-25 216591035064 Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283 216591035065 active site 216591035066 catalytic motif [active] 216591035067 Zn binding site [ion binding]; other site 216591035068 HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 3.9e-22 216591035069 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 216591035070 thymidine phosphorylase; Reviewed; Region: deoA; PRK05820 216591035071 Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885 216591035072 Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591 216591035073 Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941 216591035074 HMMPfam hit to PF07831, Pyrimidine nucleoside phosphorylase C, score 2.2e-23 216591035075 HMMPfam hit to PF00591, Glycosyl transferase family, a/b doma, score 4.3e-41 216591035076 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035077 HMMPfam hit to PF02885, Glycosyl transferase family, helical, score 5.9e-11 216591035078 Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972 216591035079 Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773 216591035080 Nucleoside recognition; Region: Gate; pfam07670 216591035081 Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662 216591035082 HMMPfam hit to PF07662, Na+ dependent nucleoside transporter C, score 4.5e-90 216591035083 10 probable transmembrane helices predicted for BCAS0730 by TMHMM2.0 at aa 4-21, 33-55, 96-118, 131-153, 173-195, 202-224, 258-280, 287-309, 363-385 and 398-420 216591035084 HMMPfam hit to PF07670, Nucleoside recognition, score 5.4e-10 216591035085 HMMPfam hit to PF01773, Na+ dependent nucleoside transporter N, score 1.1e-22 216591035086 phenylhydantoinase; Validated; Region: PRK08323 216591035087 D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314 216591035088 tetramer interface [polypeptide binding]; other site 216591035089 active site 216591035090 HMMPfam hit to PF01979, Amidohydrolase family, score 1.5e-11 216591035091 HMMPfam hit to PF07969, Amidohydrolase family, score 0.00036 216591035092 uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily, YbbW-like; solute-binding domain; Region: SLC-NCS1sbd_YbbW-like; cd11485 216591035093 Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133 216591035094 Na binding site [ion binding]; other site 216591035095 putative substrate binding site [chemical binding]; other site 216591035096 12 probable transmembrane helices predicted for BCAS0732 by TMHMM2.0 at aa 39-61, 71-93, 120-142, 157-179, 188-210, 235-257, 277-299, 319-341, 354-376, 386-408, 429-451 and 466-488 216591035097 HMMPfam hit to PF02133, Permease for cytosine/purines, uracil,, score 1.5e-130 216591035098 dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318 216591035099 Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain. DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940 216591035100 homodimer interface [polypeptide binding]; other site 216591035101 active site 216591035102 FMN binding site [chemical binding]; other site 216591035103 substrate binding site [chemical binding]; other site 216591035104 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 216591035105 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00079 216591035106 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591035107 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00045 216591035108 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 216591035109 PS00190 Cytochrome c family heme-binding site signature. 216591035110 HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, score 1.9e-11 216591035111 dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749 216591035112 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00071 216591035113 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 2.6e-19 216591035114 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 9.3e-11 216591035115 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 0.00074 216591035116 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035117 allantoate amidohydrolase; Reviewed; Region: PRK12893 216591035118 M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884 216591035119 active site 216591035120 metal binding site [ion binding]; metal-binding site 216591035121 dimer interface [polypeptide binding]; other site 216591035122 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 1e-43 216591035123 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 0.0052 216591035124 pyrimidine utilization regulatory protein R; Region: RutR; TIGR03613 216591035125 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 216591035126 YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362 216591035127 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.6e-15 216591035128 Predicted helix-turn-helix motif with score 1091.000, SD 2.90 at aa 51-72, sequence ASTAMIAERAGLPKANVHYYFP 216591035129 HMMPfam hit to PF08362, YcdC-like protein, C-terminal region, score 4.1e-76 216591035130 acetyl-CoA acetyltransferase; Provisional; Region: PRK06954 216591035131 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 216591035132 dimer interface [polypeptide binding]; other site 216591035133 active site 216591035134 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 8e-55 216591035135 PS00099 Thiolases active site. 216591035136 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 5e-118 216591035137 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK08217 216591035138 17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs; Region: HSD10-like_SDR_c; cd05371 216591035139 NAD binding site [chemical binding]; other site 216591035140 homodimer interface [polypeptide binding]; other site 216591035141 homotetramer interface [polypeptide binding]; other site 216591035142 active site 216591035143 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0018 216591035144 HMMPfam hit to PF00106, short chain dehydrogenase, score 6.8e-27 216591035145 PS00061 Short-chain dehydrogenases/reductases family signature. 216591035146 1 probable transmembrane helix predicted for BCAS0738 by TMHMM2.0 at aa 7-26 216591035147 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365 216591035148 Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS); Region: MACS_like_2; cd05973 216591035149 active site 216591035150 acyl-activating enzyme (AAE) consensus motif; other site 216591035151 putative CoA binding site [chemical binding]; other site 216591035152 AMP binding site [chemical binding]; other site 216591035153 HMMPfam hit to PF00501, AMP-binding enzyme, score 9.4e-109 216591035154 PS00455 Putative AMP-binding domain signature. 216591035155 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 216591035156 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 216591035157 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591035158 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035159 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 5e-12 216591035160 5 probable transmembrane helices predicted for BCAS0741 by TMHMM2.0 at aa 59-81, 88-110, 115-134, 194-213 and 217-239 216591035161 SnoaL-like domain; Region: SnoaL_3; pfam13474 216591035162 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 216591035163 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 216591035164 Coenzyme A binding pocket [chemical binding]; other site 216591035165 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.2e-08 216591035166 Protein of unknown function (DUF429); Region: DUF429; pfam04250 216591035167 Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317 216591035168 HD domain; Region: HD_4; pfam13328 216591035169 HMMPfam hit to PF01966, HD domain, score 2.3e-09 216591035170 P-loop containing region of AAA domain; Region: AAA_29; cl17516 216591035171 AAA domain; Region: AAA_23; pfam13476 216591035172 AAA domain; Region: AAA_27; pfam13514 216591035173 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035174 DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420 216591035175 Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840 216591035176 active site 216591035177 metal binding site [ion binding]; metal-binding site 216591035178 DNA binding site [nucleotide binding] 216591035179 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1.1e-11 216591035180 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035181 HMMPfam hit to PF02987, Late embryogenesis abundant protein, score 0.00019 216591035182 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035183 Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405 216591035184 Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019 216591035185 HMMPfam hit to PF01019, Gamma-glutamyltranspeptidase, score 2.2e-168 216591035186 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035187 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035188 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591035189 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591035190 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591035191 dimerization interface [polypeptide binding]; other site 216591035192 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.9e-39 216591035193 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.7e-19 216591035194 PS00044 Bacterial regulatory proteins, lysR family signature. 216591035195 Predicted helix-turn-helix motif with score 1630.000, SD 4.74 at aa 18-39, sequence GSLRKAADALHLTAAAVHQQIR 216591035196 Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935 216591035197 xanthine permease; Region: pbuX; TIGR03173 216591035198 HMMPfam hit to PF00860, Permease family, score 1e-51 216591035199 12 probable transmembrane helices predicted for BCAS0754 by TMHMM2.0 at aa 20-42, 55-77, 103-125, 132-154, 169-188, 195-217, 244-266, 287-305, 320-342, 349-371, 381-403 and 410-432 216591035200 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035201 PS01116 Xanthine/uracil permeases family signature. 216591035202 Predicted small integral membrane protein (DUF2165); Region: DUF2165; pfam09933 216591035203 4 probable transmembrane helices predicted for BCAS0755 by TMHMM2.0 at aa 5-27, 63-85, 105-127 and 142-159 216591035204 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 216591035205 active site 216591035206 Int/Topo IB signature motif; other site 216591035207 catalytic residues [active] 216591035208 DNA binding site [nucleotide binding] 216591035209 HMMPfam hit to PF00589, Phage integrase family, score 0.0017 216591035210 RES domain; Region: RES; pfam08808 216591035211 putative toxin-antitoxin system antitoxin component, TIGR02293 family; Region: TAS_TIGR02293 216591035212 Protein of unknown function (DUF2384); Region: DUF2384; pfam09722 216591035213 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 216591035214 PS00888 Cyclic nucleotide-binding domain signature 1. 216591035215 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035216 6 probable transmembrane helices predicted for BCAS0759 by TMHMM2.0 at aa 4108-4130, 4273-4295, 4300-4322, 4335-4357, 4362-4384 and 4396-4418 216591035217 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 216591035218 Zn2+ binding site [ion binding]; other site 216591035219 Mg2+ binding site [ion binding]; other site 216591035220 HMMPfam hit to PF01966, HD domain, score 6.6e-06 216591035221 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 216591035222 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 216591035223 conserved cys residue [active] 216591035224 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591035225 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591035226 PS00430 TonB-dependent receptor proteins signature 1. 216591035227 HMMPfam hit to PF01965, DJ-1/PfpI family, score 4.8e-24 216591035228 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 3.7e-10 216591035229 Predicted helix-turn-helix motif with score 1058.000, SD 2.79 at aa 231-252, sequence HSVAGMAKHAGMSPRHFARLFR 216591035230 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 7.7e-09 216591035231 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 216591035232 Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412 216591035233 HMMPfam hit to PF01738, Dienelactone hydrolase family, score 9.9e-58 216591035234 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 216591035235 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.2e-50 216591035236 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.5e-46 216591035237 1 probable transmembrane helix predicted for BCAS0764 by TMHMM2.0 at aa 5-27 216591035238 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035239 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915 216591035240 Protein export membrane protein; Region: SecD_SecF; cl14618 216591035241 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 216591035242 12 probable transmembrane helices predicted for BCAS0765 by TMHMM2.0 at aa 9-28, 340-359, 366-388, 392-414, 438-460, 470-492, 540-559, 869-891, 898-920, 926-948, 969-991 and 1006-1028 216591035243 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035244 periplasmic multidrug efflux lipoprotein precursor; Reviewed; Region: PRK09578 216591035245 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 216591035246 HlyD family secretion protein; Region: HlyD_3; pfam13437 216591035247 HMMPfam hit to PF00529, HlyD family secretion protein, score 1e-56 216591035248 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035249 Transcriptional regulator [Transcription]; Region: LysR; COG0583 216591035250 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591035251 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 216591035252 dimerization interface [polypeptide binding]; other site 216591035253 HMMPfam hit to PF03466, LysR substrate binding domain, score 5.4e-24 216591035254 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.9e-14 216591035255 PS00044 Bacterial regulatory proteins, lysR family signature. 216591035256 AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719 216591035257 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 216591035258 Helix-turn-helix domain; Region: HTH_18; pfam12833 216591035259 HMMPfam hit to PF06719, AraC-type transcriptional regulator N-termin, score 2.2e-20 216591035260 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 7e-07 216591035261 Predicted helix-turn-helix motif with score 1331.000, SD 3.72 at aa 230-251, sequence MVVDSLARQVEMSPSTFHHHFR 216591035262 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 216591035263 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 216591035264 substrate binding pocket [chemical binding]; other site 216591035265 membrane-bound complex binding site; other site 216591035266 hinge residues; other site 216591035267 1 probable transmembrane helix predicted for BCAS0769 by TMHMM2.0 at aa 12-34 216591035268 transcriptional regulator; Provisional; Region: PRK10632 216591035269 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591035270 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 216591035271 putative effector binding pocket; other site 216591035272 dimerization interface [polypeptide binding]; other site 216591035273 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.2e-42 216591035274 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.2e-20 216591035275 Predicted helix-turn-helix motif with score 1067.000, SD 2.82 at aa 17-38, sequence GSFTSAAQRLDITTAYASRSVA 216591035276 Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788 216591035277 Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108 216591035278 GDP-binding site [chemical binding]; other site 216591035279 ACT binding site; other site 216591035280 IMP binding site; other site 216591035281 HMMPfam hit to PF00709, Adenylosuccinate synthetase, score 2.1e-246 216591035282 PS00513 Adenylosuccinate synthetase active site. 216591035283 PS01266 Adenylosuccinate synthetase GTP-binding site. 216591035284 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 216591035285 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 216591035286 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 216591035287 dimerization interface [polypeptide binding]; other site 216591035288 substrate binding pocket [chemical binding]; other site 216591035289 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1e-21 216591035290 Predicted helix-turn-helix motif with score 1734.000, SD 5.09 at aa 21-42, sequence GSFTLAADELCVTHGAISRHVQ 216591035291 PS00044 Bacterial regulatory proteins, lysR family signature. 216591035292 HMMPfam hit to PF03466, LysR substrate binding domain, score 5.8e-41 216591035293 ParA-like protein; Provisional; Region: PHA02518 216591035294 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 216591035295 P-loop; other site 216591035296 Magnesium ion binding site [ion binding]; other site 216591035297 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035298 ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180 216591035299 HMMPfam hit to PF02195, ParB-like nuclease domain, score 6.4e-09 216591035300 Replication initiator protein A; Region: RPA; cl17860 216591035301 HMMPfam hit to PF07042, TrfA protein, score 3.2e-18 216591035302 error-prone DNA polymerase; Validated; Region: dnaE2; PRK05672 216591035303 Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at DnaE2 gene; Region: PHP_PolIIIA_DnaE2; cd07434 216591035304 putative active site [active] 216591035305 putative PHP Thumb interface [polypeptide binding]; other site 216591035306 DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485 216591035307 generic binding surface II; other site 216591035308 generic binding surface I; other site 216591035309 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 5.5e-08 216591035310 PS00211 ABC transporters family signature. 216591035311 HMMPfam hit to PF07733, Bacterial DNA polymerase III alpha sub, score 8.6e-239 216591035312 HMMPfam hit to PF02811, PHP domain, score 4.9e-06 216591035313 DNA Polymerase Y-family; Region: PolY_like; cd03468 216591035314 active site 216591035315 DNA binding site [nucleotide binding] 216591035316 Uncharacterized conserved protein [Function unknown]; Region: COG4544 216591035317 RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651 216591035318 Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078 216591035319 putative active site [active] 216591035320 putative NTP binding site [chemical binding]; other site 216591035321 putative nucleic acid binding site [nucleotide binding]; other site 216591035322 HMMPfam hit to PF00078, Reverse transcriptase (RNA-dependent DNA pol, score 1.5e-62 216591035323 Uncharacterized ACR, COG2135; Region: DUF159; pfam02586 216591035324 4 probable transmembrane helices predicted for pBS010 by TMHMM2.0 at aa 7-26, 31-48, 111-133 and 169-188 216591035325 C-terminal region is similar to Escherichia coli O6 putative adhesin c4424 SWALL:Q8FCB2 (EMBL:AE016768) (1778 aa) fasta scores: E(): 3.5e-33, 29.02% id in 1795 aa. CDS contains a probable frameshift mutation 216591035326 HMMPfam hit to PF03895, YadA-like C-terminal region, score 1.2e-15 216591035327 HMMPfam hit to PF05658, Hep_Hag, score 0.00015 216591035328 HMMPfam hit to PF05658, Hep_Hag, score 0.0023 216591035329 HMMPfam hit to PF05662, Haemagglutinin, score 4.6e-06 216591035330 HMMPfam hit to PF05662, Haemagglutinin, score 1.7e-05 216591035331 HMMPfam hit to PF05662, Haemagglutinin, score 1.3e-05 216591035332 HMMPfam hit to PF05662, Haemagglutinin, score 0.00012 216591035333 HMMPfam hit to PF05662, Haemagglutinin, score 1.3e-05 216591035334 HMMPfam hit to PF05662, Haemagglutinin, score 1.4e-05 216591035335 HMMPfam hit to PF05662, Haemagglutinin, score 7e-06 216591035336 HMMPfam hit to PF05662, Haemagglutinin, score 0.0001 216591035337 HMMPfam hit to PF05662, Haemagglutinin, score 3e-05 216591035338 HMMPfam hit to PF05662, Haemagglutinin, score 6.4e-05 216591035339 HMMPfam hit to PF05662, Haemagglutinin, score 1.8e-05 216591035340 HMMPfam hit to PF05658, Hep_Hag, score 0.15 216591035341 HMMPfam hit to PF05658, Hep_Hag, score 1.1 216591035342 HMMPfam hit to PF05658, Hep_Hag, score 0.85 216591035343 HMMPfam hit to PF05658, Hep_Hag, score 3e-05 216591035344 Bacterial PH domain; Region: DUF304; pfam03703 216591035345 2 probable transmembrane helices predicted for pBS014 by TMHMM2.0 at aa 13-35 and 45-64 216591035346 Protein of unknown function (DUF1173); Region: DUF1173; pfam06666 216591035347 HMMPfam hit to PF06666, Protein of unknown function (DUF1173), score 1.1e-140 216591035348 Zeta toxin; Region: Zeta_toxin; pfam06414 216591035349 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4185 216591035350 HMMPfam hit to PF06414, Zeta toxin, score 9.5e-62 216591035351 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035352 2 probable transmembrane helices predicted for pBS019 by TMHMM2.0 at aa 61-83 and 93-110 216591035353 TraG-like protein, N-terminal region; Region: TraG_N; pfam07916 216591035354 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 216591035355 HMMPfam hit to PF07916, TraG-like protein, N-terminal region, score 1.3e-52 216591035356 5 probable transmembrane helices predicted for pBS020 by TMHMM2.0 at aa 26-48, 58-80, 337-359, 369-391 and 424-441 216591035357 Conjugative relaxosome accessory transposon protein; Region: TraH; pfam06122 216591035358 HMMPfam hit to PF06122, TraH protein, score 1.1e-71 216591035359 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035360 Phage protein Gp37/Gp68; Region: Gp37_Gp68; cl15384 216591035361 HMMPfam hit to PF07505, Phage protein Gp37/Gp68, score 6.7e-108 216591035362 HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085 216591035363 active site 216591035364 HMMPfam hit to PF01844, HNH endonuclease, score 3e-07 216591035365 F plasmid transfer operon protein; Region: TraF; pfam13728 216591035366 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 216591035367 catalytic residues [active] 216591035368 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 216591035369 conjugal transfer mating pair stabilization protein TraN; Reviewed; Region: PRK12355 216591035370 conjugal transfer mating pair stabilization protein TraN; Reviewed; Region: PRK12355 216591035371 2 probable transmembrane helices predicted for pBS029 by TMHMM2.0 at aa 12-34 and 44-66 216591035372 Type-F conjugative transfer system pilin assembly protein; Region: TrbC_Ftype; pfam09673 216591035373 1 probable transmembrane helix predicted for pBS030 by TMHMM2.0 at aa 13-35 216591035374 TraU protein; Region: TraU; pfam06834 216591035375 HMMPfam hit to PF06834, TraU protein, score 6.8e-147 216591035376 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035377 Sex factor F TraW protein N terminal; Region: TraW_N; cl10149 216591035378 conjugal transfer pilin processing protease TraF; Provisional; Region: PRK13838 216591035379 conjugative transfer signal peptidase TraF; Region: TraF_Ti; TIGR02771 216591035380 HMMPfam hit to PF00717, Peptidase S24-like, score 0.02 216591035381 PS00760 Signal peptidases I lysine active site. 216591035382 1 probable transmembrane helix predicted for pBS033 by TMHMM2.0 at aa 20-42 216591035383 2 probable transmembrane helices predicted for pBS034 by TMHMM2.0 at aa 7-29 and 33-52 216591035384 Transcriptional regulators [Transcription]; Region: FadR; COG2186 216591035385 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 216591035386 DNA-binding site [nucleotide binding]; DNA binding site 216591035387 HMMPfam hit to PF07729, FCD domain, score 0.00029 216591035388 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.1e-10 216591035389 PS00043 Bacterial regulatory proteins, gntR family signature. 216591035390 Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170 216591035391 PLD-like domain; Region: PLDc_2; pfam13091 216591035392 putative active site [active] 216591035393 catalytic site [active] 216591035394 1 probable transmembrane helix predicted for pBS036 by TMHMM2.0 at aa 13-35 216591035395 3 probable transmembrane helices predicted for pBS037 by TMHMM2.0 at aa 10-32, 44-66 and 76-98 216591035396 F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130 216591035397 type-IV secretion system protein TraC; Region: TraC-F-type; TIGR02746 216591035398 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 216591035399 Walker A motif; other site 216591035400 ATP binding site [chemical binding]; other site 216591035401 Walker B motif; other site 216591035402 PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 216591035403 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035404 Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676 216591035405 DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020 216591035406 dimerization domain [polypeptide binding]; other site 216591035407 dimer interface [polypeptide binding]; other site 216591035408 catalytic residues [active] 216591035409 Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743 216591035410 HMMPfam hit to PF06447, TraB pilus assembly protein, score 1.7e-38 216591035411 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035412 1 probable transmembrane helix predicted for pBS044 by TMHMM2.0 at aa 23-42 216591035413 TraK protein; Region: TraK; pfam06586 216591035414 conjugal transfer protein TraK; Provisional; Region: PRK13736; cl05878 216591035415 TraE protein; Region: TraE; cl05060 216591035416 1 probable transmembrane helix predicted for pBS046 by TMHMM2.0 at aa 20-42 216591035417 TraL protein; Region: TraL; cl06278 216591035418 1 probable transmembrane helix predicted for pBS047 by TMHMM2.0 at aa 32-54 216591035419 3 probable transmembrane helices predicted for pBS048 by TMHMM2.0 at aa 37-59, 79-98 and 105-127 216591035420 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 216591035421 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 216591035422 N-acetyl-D-glucosamine binding site [chemical binding]; other site 216591035423 catalytic residue [active] 216591035424 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 2.7e-28 216591035425 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035426 Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800 216591035427 putative active site [active] 216591035428 HMMPfam hit to PF03746, LamB/YcsF family, score 3.7e-85 216591035429 Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; cl15441 216591035430 HMMPfam hit to PF03480, Bacterial extracellular solute-binding prot, score 1.3e-07 216591035431 Autoinducer binding domain; Region: Autoind_bind; pfam03472 216591035432 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315 216591035433 DNA binding residues [nucleotide binding] 216591035434 dimerization interface [polypeptide binding]; other site 216591035435 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 0.00015 216591035436 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 216591035437 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 216591035438 metal binding site [ion binding]; metal-binding site 216591035439 active site 216591035440 I-site; other site 216591035441 EAL domain; Region: EAL; pfam00563 216591035442 HMMPfam hit to PF00563, EAL domain, score 2.7e-07 216591035443 HMMPfam hit to PF00990, GGDEF domain, score 1.5e-22 216591035444 2 probable transmembrane helices predicted for pBS055 by TMHMM2.0 at aa 26-45 and 298-317 216591035445 TrwC relaxase; Region: TrwC; pfam08751 216591035446 conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686 216591035447 AAA domain; Region: AAA_30; pfam13604 216591035448 Family description; Region: UvrD_C_2; pfam13538 216591035449 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035450 Probable gene remnant. Similar to the N-terminal regions of Escherichia coli thiol:disulfide interchange protein precursor DsbD or DipZ or CycZ or CutA2 or b4136 SWALL:DSBD_ECOLI (SWALL:P36655) (565 aa) fasta scores: E(): 9.3e-05, 30.49% id in 141 aa, and to Ralstonia solanacearum thiol:disulfide interchange protein dsbD precursor rsc2990 or rs01128 SWALL:DSBD_RALSO (SWALL:Q8XV41) (608 aa) fasta scores: E(): 1.8e-11, 38.19% id in 144 aa 216591035451 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 216591035452 Type IV secretion-system coupling protein DNA-binding domain; Region: TrwB_AAD_bind; pfam10412 216591035453 Walker A motif; other site 216591035454 ATP binding site [chemical binding]; other site 216591035455 Walker B motif; other site 216591035456 PS00017 ATP/GTP-binding site motif A (P-loop). 216591035457 2 probable transmembrane helices predicted for pBS059 by TMHMM2.0 at aa 31-53 and 115-137 216591035458 PRLI-interacting factor K; Provisional; Region: PLN03086 216591035459 1 probable transmembrane helix predicted for pBS064 by TMHMM2.0 at aa 20-37 216591035460 Protein of unknown function (DUF3717); Region: DUF3717; pfam12512 216591035461 ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180 216591035462 ParB-like nuclease domain; Region: ParBc; pfam02195 216591035463 HMMPfam hit to PF02195, ParB-like nuclease domain, score 6.9e-13 216591035464 DNA methylase; Region: N6_N4_Mtase; cl17433 216591035465 DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863 216591035466 HMMPfam hit to PF01555, DNA methylase, score 2.9e-38 216591035467 PS00092 N-6 Adenine-specific DNA methylases signature. 216591035468 Domain of unknown function (DUF932); Region: DUF932; pfam06067 216591035469 HMMPfam hit to PF06067, Domain of unknown function (DUF932), score 2e-187 216591035470 Similar to the N-terminal regions of Pseudomonas aeruginosa hypothetical protein pa2221 SWALL:Q9I1P8 (EMBL:AE004648) (401 aa) fasta scores: E(): 0.0033, 43.75% id in 48 aa, and Ralstonia solanacearum probable transposase protein rsc1842 or rs04281 SWALL:Q8XYB6 (EMBL:AL646067) (130 aa) fasta scores: E(): 0.09, 44% id in 50 aa 216591035471 Similar to internal regions of Pseudomonas aeruginosa hypothetical protein pa2221 SWALL:Q9I1P8 (EMBL:AE004648) (401 aa) fasta scores: E(): 0.00095, 42.37% id in 59 aa, and Ralstonia solanacearum probable transposase protein rsc1843 or rs05589 SWALL:Q8XYB5 (EMBL:AL646067) (491 aa) fasta scores: E(): 0.00022, 41.53% id in 65 aa 216591035472 Transposase; Region: HTH_Tnp_1; pfam01527 216591035473 HMMPfam hit to PF01527, Transposase, score 1.6e-29 216591035474 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801 216591035475 HTH-like domain; Region: HTH_21; pfam13276 216591035476 Integrase core domain; Region: rve; pfam00665 216591035477 Integrase core domain; Region: rve_3; pfam13683 216591035478 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 216591035479 Similar to an internal region of Rhizobium sp. nodulation protein NolO or y4hD SWALL:NOLO_RHISN (SWALL:P55474) (680 aa) fasta scores: E(): 7.6e-26, 36.58% id in 287 aa, and to the C-teminal region of Methanococcus jannaschii hypothetical protein Mj1058 mj1058 SWALL:YA58_METJA (SWALL:Q58458) (609 aa) fasta scores: E(): 1.9e-25, 36.76% id in 272 aa. CDS is truncated by the insertion of the upstream IS element and subsequent recombination events. Possible gene remnant 216591035480 UDP-N-acetylmuramate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: MurB; COG0812 216591035481 FAD binding domain; Region: FAD_binding_4; pfam01565 216591035482 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873 216591035483 HMMPfam hit to PF01565, FAD binding domain, score 0.00047 216591035484 HMMPfam hit to PF02873, UDP-N-acetylenolpyruvoylglucosamine red, score 5.4e-09 216591035485 HMMPfam hit to PF00293, NUDIX domain, score 0.021 216591035486 Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; Region: SsnA; COG0402 216591035487 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 216591035488 HMMPfam hit to PF01979, Amidohydrolase family, score 0.01 216591035489 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 216591035490 Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929 216591035491 HMMPfam hit to PF07929, Plasmid pRiA4b ORF-3-like protein, score 1.3e-62 216591035492 Similar to the C-terminal regions of Xanthomonas campestris resolvase TnpR SWALL:Q9RCD3 (EMBL:Y17691) (308 aa) fasta scores: E(): 3.5e-05, 34.25% id in 108 aa, and to Pseudomonas putida putative resolvase Res2 SWALL:Q847J0 (EMBL:AF491307) (157 aa) fasta scores: E(): 0.00024, 35.48% id in 93 aa 216591035493 Phage integrase protein; Region: DUF3701; pfam12482 216591035494 tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224 216591035495 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 216591035496 active site 216591035497 catalytic residues [active] 216591035498 DNA binding site [nucleotide binding] 216591035499 Int/Topo IB signature motif; other site 216591035500 HMMPfam hit to PF00589, Phage integrase family, score 9.9e-13 216591035501 PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881 216591035502 oligomeric interface; other site 216591035503 putative active site [active] 216591035504 homodimer interface [polypeptide binding]; other site 216591035505 HMMPfam hit to PF01850, PIN domain, score 4.2e-27 216591035506 Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456 216591035507 HMMPfam hit to PF04014, SpoVT / AbrB like domain, score 0.00035 216591035508 Adenylation domain of Mycobacterium tuberculosis LigD and LigC-like ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_LigD_LigC; cd07906 216591035509 DNA polymerase LigD, ligase domain; Region: NHEJ_ligase_lig; TIGR02779 216591035510 active site 216591035511 DNA binding site [nucleotide binding] 216591035512 The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase LigD is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_LigD; cd07971 216591035513 DNA binding site [nucleotide binding] 216591035514 HMMPfam hit to PF04679, ATP dependent DNA ligase C terminal re, score 0.0044 216591035515 HMMPfam hit to PF01068, ATP dependent DNA ligase domain, score 2.2e-22 216591035516 PS00697 ATP-dependent DNA ligase AMP-binding site.