-- dump date   	20140619_011822
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
107806000001	anthranilate synthase component I; Provisional; Region: PRK13564
107806000002	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
107806000003	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
107806000004	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
107806000005	Glutamine amidotransferase class-I; Region: GATase; pfam00117
107806000006	glutamine binding [chemical binding]; other site
107806000007	catalytic triad [active]
107806000008	authentic frameshift; This 1568 nt putative ORF is 99 pct identical to trpE
107806000009	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
107806000010	Glutamine amidotransferase class-I; Region: GATase; pfam00117
107806000011	glutamine binding [chemical binding]; other site
107806000012	catalytic triad [active]
107806000013	IncFII RepA protein family; Region: IncFII_repA; pfam02387
107806000014	hypothetical protein; Provisional; Region: PRK05208
107806000015	IncFII RepA protein family; Region: IncFII_repA; cl11495
107806000016	2-isopropylmalate synthase; Validated; Region: PRK00915
107806000017	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
107806000018	active site
107806000019	catalytic residues [active]
107806000020	metal binding site [ion binding]; metal-binding site
107806000021	LeuA allosteric (dimerization) domain; Region: LeuA_dimer; pfam08502
107806000022	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
107806000023	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
107806000024	substrate binding site [chemical binding]; other site
107806000025	ligand binding site [chemical binding]; other site
107806000026	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
107806000027	substrate binding site [chemical binding]; other site
107806000028	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
107806000029	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
107806000030	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
107806000031	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
107806000032	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
107806000033	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
107806000034	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
107806000035	F0F1 ATP synthase subunit B; Provisional; Region: PRK14471; cl17192
107806000036	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
107806000037	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
107806000038	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
107806000039	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
107806000040	beta subunit interaction interface [polypeptide binding]; other site
107806000041	Walker A motif; other site
107806000042	ATP binding site [chemical binding]; other site
107806000043	Walker B motif; other site
107806000044	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
107806000045	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
107806000046	core domain interface [polypeptide binding]; other site
107806000047	delta subunit interface [polypeptide binding]; other site
107806000048	epsilon subunit interface [polypeptide binding]; other site
107806000049	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
107806000050	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
107806000051	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
107806000052	alpha subunit interaction interface [polypeptide binding]; other site
107806000053	Walker A motif; other site
107806000054	ATP binding site [chemical binding]; other site
107806000055	Walker B motif; other site
107806000056	inhibitor binding site; inhibition site
107806000057	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
107806000058	ATP synthase, F1 epsilon subunit (delta in mitochondria); Region: ATP_synt_epsi; TIGR01216
107806000059	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
107806000060	gamma subunit interface [polypeptide binding]; other site
107806000061	epsilon subunit interface [polypeptide binding]; other site
107806000062	LBP interface [polypeptide binding]; other site
107806000063	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
107806000064	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
107806000065	ATP binding site [chemical binding]; other site
107806000066	Mg2+ binding site [ion binding]; other site
107806000067	G-X-G motif; other site
107806000068	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
107806000069	anchoring element; other site
107806000070	dimer interface [polypeptide binding]; other site
107806000071	ATP binding site [chemical binding]; other site
107806000072	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
107806000073	active site
107806000074	putative metal-binding site [ion binding]; other site
107806000075	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
107806000076	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
107806000077	DNA polymerase III subunit beta; Validated; Region: PRK05643
107806000078	putative DNA binding surface [nucleotide binding]; other site
107806000079	dimer interface [polypeptide binding]; other site
107806000080	beta-clamp/clamp loader binding surface; other site
107806000081	beta-clamp/translesion DNA polymerase binding surface; other site
107806000082	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
107806000083	DnaA N-terminal domain; Region: DnaA_N; pfam11638
107806000084	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
107806000085	Walker A motif; other site
107806000086	ATP binding site [chemical binding]; other site
107806000087	Walker B motif; other site
107806000088	arginine finger; other site
107806000089	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
107806000090	DnaA box-binding interface [nucleotide binding]; other site
107806000091	Ribosomal protein L34 [Translation, ribosomal structure and biogenesis]; Region: RpmH; COG0230
107806000092	ribonuclease P; Reviewed; Region: rnpA; PRK01732
107806000093	membrane protein insertase; Provisional; Region: PRK01318
107806000094	YidC periplasmic domain; Region: YidC_periplas; pfam14849
107806000095	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
107806000096	Predicted GTPase [General function prediction only]; Region: ThdF; COG0486
107806000097	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
107806000098	trmE is a tRNA modification GTPase; Region: trmE; cd04164
107806000099	G1 box; other site
107806000100	GTP/Mg2+ binding site [chemical binding]; other site
107806000101	Switch I region; other site
107806000102	G2 box; other site
107806000103	Switch II region; other site
107806000104	G3 box; other site
107806000105	G4 box; other site
107806000106	G5 box; other site
107806000107	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
107806000108	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
107806000109	oligomerisation interface [polypeptide binding]; other site
107806000110	mobile loop; other site
107806000111	roof hairpin; other site
107806000112	chaperonin GroEL; Reviewed; Region: groEL; PRK12850
107806000113	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
107806000114	ring oligomerisation interface [polypeptide binding]; other site
107806000115	ATP/Mg binding site [chemical binding]; other site
107806000116	stacking interactions; other site
107806000117	hinge regions; other site
107806000118	translation elongation factor P; Region: efp; TIGR00038
107806000119	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
107806000120	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
107806000121	RNA binding site [nucleotide binding]; other site
107806000122	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
107806000123	RNA binding site [nucleotide binding]; other site
107806000124	DNA replication protein DnaC; Validated; Region: PRK07952
107806000125	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
107806000126	Walker A motif; other site
107806000127	ATP binding site [chemical binding]; other site
107806000128	Walker B motif; other site
107806000129	primosomal protein DnaI; Provisional; Region: PRK02854
107806000130	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
107806000131	S-adenosylmethionine binding site [chemical binding]; other site
107806000132	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
107806000133	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
107806000134	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
107806000135	P loop; other site
107806000136	GTP binding site [chemical binding]; other site
107806000137	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
107806000138	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
107806000139	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
107806000140	DNA binding residues [nucleotide binding]
107806000141	glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Region: glmS; TIGR01135
107806000142	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
107806000143	glutaminase active site [active]
107806000144	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
107806000145	dimer interface [polypeptide binding]; other site
107806000146	active site
107806000147	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
107806000148	dimer interface [polypeptide binding]; other site
107806000149	active site
107806000150	UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Region: glmU; TIGR01173
107806000151	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
107806000152	Substrate binding site; other site
107806000153	Mg++ binding site; other site
107806000154	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
107806000155	active site
107806000156	substrate binding site [chemical binding]; other site
107806000157	CoA binding site [chemical binding]; other site
107806000158	putative hydrolase; Provisional; Region: PRK10976
107806000159	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
107806000160	active site
107806000161	motif I; other site
107806000162	motif II; other site
107806000163	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
107806000164	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
107806000165	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
107806000166	THF binding site; other site
107806000167	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
107806000168	substrate binding site [chemical binding]; other site
107806000169	THF binding site; other site
107806000170	zinc-binding site [ion binding]; other site
107806000171	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
107806000172	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
107806000173	purine monophosphate binding site [chemical binding]; other site
107806000174	dimer interface [polypeptide binding]; other site
107806000175	putative catalytic residues [active]
107806000176	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
107806000177	histone-like DNA-binding protein HU; Region: HU; cd13831
107806000178	dimer interface [polypeptide binding]; other site
107806000179	DNA binding site [nucleotide binding]
107806000180	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
107806000181	Largest subunit (beta') of bacterial DNA-dependent RNA polymerase (RNAP), N-terminal domain; Region: RNAP_beta'_N; cd01609
107806000182	beta and beta' interface [polypeptide binding]; other site
107806000183	beta' and sigma factor interface [polypeptide binding]; other site
107806000184	Zn-binding [ion binding]; other site
107806000185	active site region [active]
107806000186	catalytic site [active]
107806000187	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
107806000188	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
107806000189	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
107806000190	DNA binding site [nucleotide binding]
107806000191	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
107806000192	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
107806000193	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
107806000194	RPB12 interaction site [polypeptide binding]; other site
107806000195	RPB1 interaction site [polypeptide binding]; other site
107806000196	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
107806000197	RPB10 interaction site [polypeptide binding]; other site
107806000198	RPB11 interaction site [polypeptide binding]; other site
107806000199	RPB3 interaction site [polypeptide binding]; other site
107806000200	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
107806000201	core dimer interface [polypeptide binding]; other site
107806000202	peripheral dimer interface [polypeptide binding]; other site
107806000203	L10 interface [polypeptide binding]; other site
107806000204	L11 interface [polypeptide binding]; other site
107806000205	putative EF-Tu interaction site [polypeptide binding]; other site
107806000206	putative EF-G interaction site [polypeptide binding]; other site
107806000207	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
107806000208	23S rRNA interface [nucleotide binding]; other site
107806000209	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
107806000210	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
107806000211	mRNA/rRNA interface [nucleotide binding]; other site
107806000212	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
107806000213	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
107806000214	23S rRNA interface [nucleotide binding]; other site
107806000215	L7/L12 interface [polypeptide binding]; other site
107806000216	putative thiostrepton binding site; other site
107806000217	L25 interface [polypeptide binding]; other site
107806000218	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
107806000219	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
107806000220	putative homodimer interface [polypeptide binding]; other site
107806000221	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
107806000222	heterodimer interface [polypeptide binding]; other site
107806000223	homodimer interface [polypeptide binding]; other site
107806000224	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
107806000225	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
107806000226	FAD binding domain; Region: FAD_binding_4; pfam01565
107806000227	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
107806000228	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
107806000229	FAD binding site [chemical binding]; other site
107806000230	acetylornithine deacetylase (ArgE); Region: AcOrn-deacetyl; TIGR01892
107806000231	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
107806000232	metal binding site [ion binding]; metal-binding site
107806000233	putative dimer interface [polypeptide binding]; other site
107806000234	N-acetyl-gamma-glutamyl-phosphate reductase, common form; Region: argC; TIGR01850
107806000235	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
107806000236	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; cl19935
107806000237	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
107806000238	nucleotide binding site [chemical binding]; other site
107806000239	substrate binding site [chemical binding]; other site
107806000240	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
107806000241	ANP binding site [chemical binding]; other site
107806000242	Substrate Binding Site II [chemical binding]; other site
107806000243	Substrate Binding Site I [chemical binding]; other site
107806000244	argininosuccinate lyase; Provisional; Region: PRK04833
107806000245	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
107806000246	active sites [active]
107806000247	tetramer interface [polypeptide binding]; other site
107806000248	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
107806000249	active site residue [active]
107806000250	Preprotein translocase subunit SecB [Intracellular trafficking and secretion]; Region: SecB; COG1952
107806000251	SecA binding site; other site
107806000252	Preprotein binding site; other site
107806000253	Serine acetyltransferase, N-terminal; Region: SATase_N; smart00971
107806000254	serine O-acetyltransferase; Region: cysE; TIGR01172
107806000255	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
107806000256	trimer interface [polypeptide binding]; other site
107806000257	active site
107806000258	substrate binding site [chemical binding]; other site
107806000259	CoA binding site [chemical binding]; other site
107806000260	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
107806000261	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
107806000262	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
107806000263	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
107806000264	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
107806000265	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
107806000266	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
107806000267	DNA binding residues [nucleotide binding]
107806000268	DNA primase; Validated; Region: dnaG; PRK05667
107806000269	CHC2 zinc finger; Region: zf-CHC2; cl17510
107806000270	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
107806000271	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
107806000272	active site
107806000273	metal binding site [ion binding]; metal-binding site
107806000274	interdomain interaction site; other site
107806000275	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
107806000276	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; smart00766
107806000277	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
107806000278	UGMP family protein; Validated; Region: PRK09604
107806000279	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
107806000280	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
107806000281	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
107806000282	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
107806000283	putative ribose interaction site [chemical binding]; other site
107806000284	putative ADP binding site [chemical binding]; other site
107806000285	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13298
107806000286	Poly A polymerase head domain; Region: PolyA_pol; pfam01743
107806000287	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
107806000288	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
107806000289	PTS system glucose-specific transporter subunit; Provisional; Region: PRK09439
107806000290	HPr interaction site; other site
107806000291	glycerol kinase (GK) interaction site [polypeptide binding]; other site
107806000292	active site
107806000293	phosphorylation site [posttranslational modification]
107806000294	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
107806000295	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
107806000296	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
107806000297	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
107806000298	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
107806000299	dimerization domain swap beta strand [polypeptide binding]; other site
107806000300	regulatory protein interface [polypeptide binding]; other site
107806000301	active site
107806000302	regulatory phosphorylation site [posttranslational modification]; other site
107806000303	cysteine synthase; Region: PLN02565
107806000304	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
107806000305	dimer interface [polypeptide binding]; other site
107806000306	pyridoxal 5'-phosphate binding site [chemical binding]; other site
107806000307	catalytic residue [active]
107806000308	NAD-dependent DNA ligase (contains BRCT domain type II) [DNA replication, recombination, and repair]; Region: Lig; COG0272
107806000309	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
107806000310	nucleotide binding pocket [chemical binding]; other site
107806000311	K-X-D-G motif; other site
107806000312	catalytic site [active]
107806000313	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
107806000314	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
107806000315	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
107806000316	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
107806000317	Dimer interface [polypeptide binding]; other site
107806000318	BRCT sequence motif; other site
107806000319	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
107806000320	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
107806000321	active site
107806000322	HIGH motif; other site
107806000323	KMSKS motif; other site
107806000324	Flagellar hook-basal body protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliE; COG1677
107806000325	Flagellar basal body M-ring protein [Cell motility and secretion]; Region: fliF; COG1766
107806000326	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
107806000327	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
107806000328	Flagellar motor switch protein [Cell motility and secretion]; Region: FliG; COG1536
107806000329	FliG N-terminal domain; Region: FliG_N; pfam14842
107806000330	FliG middle domain; Region: FliG_M; pfam14841
107806000331	FliG C-terminal domain; Region: FliG_C; pfam01706
107806000332	Flagellar biosynthesis/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliH; COG1317
107806000333	Flagellar assembly protein FliH; Region: FliH; pfam02108
107806000334	flagellar protein export ATPase FliI; Region: FliI_clade1; TIGR03496
107806000335	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
107806000336	Walker A motif; other site
107806000337	ATP binding site [chemical binding]; other site
107806000338	Walker B motif; other site
107806000339	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
107806000340	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
107806000341	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
107806000342	Flagellar motor switch protein [Cell motility and secretion]; Region: FliM; COG1868
107806000343	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
107806000344	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
107806000345	putative bifunctional flagellar biosynthesis protein FliO/FliP; Provisional; Region: PRK12430
107806000346	Flagellar biogenesis protein [Cell motility and secretion]; Region: FliO; COG3190
107806000347	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
107806000348	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
107806000349	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
107806000350	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
107806000351	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
107806000352	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
107806000353	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
107806000354	dimer interface [polypeptide binding]; other site
107806000355	substrate binding site [chemical binding]; other site
107806000356	metal binding sites [ion binding]; metal-binding site
107806000357	Putative modulator of DNA gyrase; Region: PmbA_TldD; cl19356
107806000358	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
107806000359	putative SAM binding site [chemical binding]; other site
107806000360	putative homodimer interface [polypeptide binding]; other site
107806000361	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
107806000362	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
107806000363	dimer interface [polypeptide binding]; other site
107806000364	active site
107806000365	transaldolase-like protein; Provisional; Region: PTZ00411
107806000366	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
107806000367	active site
107806000368	dimer interface [polypeptide binding]; other site
107806000369	catalytic residue [active]
107806000370	transketolase; Reviewed; Region: PRK12753
107806000371	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
107806000372	TPP-binding site [chemical binding]; other site
107806000373	dimer interface [polypeptide binding]; other site
107806000374	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
107806000375	PYR/PP interface [polypeptide binding]; other site
107806000376	dimer interface [polypeptide binding]; other site
107806000377	TPP binding site [chemical binding]; other site
107806000378	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
107806000379	succinyl-diaminopimelate desuccinylase, proteobacterial clade; Region: dapE_proteo; TIGR01246
107806000380	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
107806000381	metal binding site [ion binding]; metal-binding site
107806000382	dimer interface [polypeptide binding]; other site
107806000383	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
107806000384	dimer interface [polypeptide binding]; other site
107806000385	active site
107806000386	catalytic residue [active]
107806000387	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
107806000388	Tetramer interface [polypeptide binding]; other site
107806000389	active site
107806000390	FMN-binding site [chemical binding]; other site
107806000391	hypothetical protein; Provisional; Region: PRK04946
107806000392	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
107806000393	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
107806000394	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
107806000395	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
107806000396	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
107806000397	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
107806000398	NAD binding site [chemical binding]; other site
107806000399	dimerization interface [polypeptide binding]; other site
107806000400	product binding site; other site
107806000401	substrate binding site [chemical binding]; other site
107806000402	zinc binding site [ion binding]; other site
107806000403	catalytic residues [active]
107806000404	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
107806000405	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
107806000406	pyridoxal 5'-phosphate binding site [chemical binding]; other site
107806000407	homodimer interface [polypeptide binding]; other site
107806000408	catalytic residue [active]
107806000409	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
107806000410	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
107806000411	active site
107806000412	motif I; other site
107806000413	motif II; other site
107806000414	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
107806000415	putative active site pocket [active]
107806000416	4-fold oligomerization interface [polypeptide binding]; other site
107806000417	metal binding residues [ion binding]; metal-binding site
107806000418	3-fold/trimer interface [polypeptide binding]; other site
107806000419	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13142
107806000420	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
107806000421	putative active site [active]
107806000422	oxyanion strand; other site
107806000423	catalytic triad [active]
107806000424	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
107806000425	catalytic residues [active]
107806000426	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
107806000427	substrate binding site [chemical binding]; other site
107806000428	glutamase interaction surface [polypeptide binding]; other site
107806000429	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
107806000430	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
107806000431	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
107806000432	metal binding site [ion binding]; metal-binding site
107806000433	6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG0362
107806000434	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
107806000435	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
107806000436	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
107806000437	trimer interface [polypeptide binding]; other site
107806000438	active site
107806000439	methionyl-tRNA synthetase; Reviewed; Region: PRK12268
107806000440	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
107806000441	active site
107806000442	nucleotide binding site [chemical binding]; other site
107806000443	HIGH motif; other site
107806000444	KMSKS motif; other site
107806000445	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
107806000446	tRNA binding surface [nucleotide binding]; other site
107806000447	anticodon binding site; other site
107806000448	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
107806000449	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
107806000450	Ligand Binding Site [chemical binding]; other site
107806000451	TilS substrate binding domain; Region: TilS; pfam09179
107806000452	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
107806000453	Riboflavin synthase alpha chain [Coenzyme metabolism]; Region: RibC; COG0307
107806000454	Lumazine binding domain; Region: Lum_binding; pfam00677
107806000455	Lumazine binding domain; Region: Lum_binding; pfam00677
107806000456	electron transport complex protein RsxA; Provisional; Region: PRK05151
107806000457	electron transport complex, RnfABCDGE type, B subunit; Region: rnfB; TIGR01944
107806000458	Putative Fe-S cluster; Region: FeS; pfam04060
107806000459	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
107806000460	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
107806000461	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
107806000462	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
107806000463	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
107806000464	electron transport complex, RnfABCDGE type, D subunit; Region: rnfD; TIGR01946
107806000465	Predicted NADH:ubiquinone oxidoreductase, subunit RnfG [Energy production and conversion]; Region: RnfG; COG4659
107806000466	Predicted NADH:ubiquinone oxidoreductase, subunit RnfE [Energy production and conversion]; Region: RnfE; COG4660
107806000467	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
107806000468	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
107806000469	minor groove reading motif; other site
107806000470	helix-hairpin-helix signature motif; other site
107806000471	substrate binding pocket [chemical binding]; other site
107806000472	active site
107806000473	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
107806000474	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
107806000475	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
107806000476	active site
107806000477	HIGH motif; other site
107806000478	dimer interface [polypeptide binding]; other site
107806000479	KMSKS motif; other site
107806000480	S4 RNA-binding domain; Region: S4; smart00363
107806000481	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
107806000482	putative inner membrane protein; Provisional; Region: PRK10983
107806000483	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
107806000484	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
107806000485	The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information...; Region: TGS; cl15768
107806000486	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
107806000487	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
107806000488	active site
107806000489	dimer interface [polypeptide binding]; other site
107806000490	motif 1; other site
107806000491	motif 2; other site
107806000492	motif 3; other site
107806000493	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
107806000494	anticodon binding site; other site
107806000495	Translation initiation factor 3 (IF-3) [Translation, ribosomal structure and biogenesis]; Region: InfC; COG0290
107806000496	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
107806000497	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
107806000498	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
107806000499	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
107806000500	23S rRNA binding site [nucleotide binding]; other site
107806000501	L21 binding site [polypeptide binding]; other site
107806000502	L13 binding site [polypeptide binding]; other site
107806000503	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
107806000504	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
107806000505	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
107806000506	dimer interface [polypeptide binding]; other site
107806000507	motif 1; other site
107806000508	active site
107806000509	motif 2; other site
107806000510	motif 3; other site
107806000511	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
107806000512	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
107806000513	putative tRNA-binding site [nucleotide binding]; other site
107806000514	B3/4 domain; Region: B3_4; pfam03483
107806000515	tRNA synthetase B5 domain; Region: B5; smart00874
107806000516	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
107806000517	dimer interface [polypeptide binding]; other site
107806000518	motif 1; other site
107806000519	motif 3; other site
107806000520	motif 2; other site
107806000521	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
107806000522	Alpha subunit of integration host factor (IHFA); Region: IHF_A; cd13835
107806000523	DNA binding site [nucleotide binding]
107806000524	dimer interface [polypeptide binding]; other site
107806000525	S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; Region: QueA; COG0809
107806000526	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
107806000527	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
107806000528	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
107806000529	Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; Region: GlyS; COG0751
107806000530	Glycyl-tRNA synthetase beta subunit; Region: tRNA_synt_2f; pfam02092
107806000531	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
107806000532	Glycyl-tRNA synthetase, alpha subunit [Translation, ribosomal structure and biogenesis]; Region: GlyQ; COG0752
107806000533	motif 1; other site
107806000534	dimer interface [polypeptide binding]; other site
107806000535	active site
107806000536	motif 2; other site
107806000537	motif 3; other site
107806000538	Endonuclease IV [DNA replication, recombination, and repair]; Region: Nfo; COG0648
107806000539	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
107806000540	AP (apurinic/apyrimidinic) site pocket; other site
107806000541	DNA interaction; other site
107806000542	Metal-binding active site; metal-binding site
107806000543	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
107806000544	5S rRNA interface [nucleotide binding]; other site
107806000545	CTC domain interface [polypeptide binding]; other site
107806000546	L16 interface [polypeptide binding]; other site
107806000547	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
107806000548	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
107806000549	SurA N-terminal domain; Region: SurA_N; pfam09312
107806000550	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
107806000551	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
107806000552	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
107806000553	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
107806000554	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
107806000555	active site
107806000556	metal binding site [ion binding]; metal-binding site
107806000557	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
107806000558	folate binding site [chemical binding]; other site
107806000559	NADP+ binding site [chemical binding]; other site
107806000560	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
107806000561	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
107806000562	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
107806000563	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
107806000564	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
107806000565	ATP-grasp domain; Region: ATP-grasp_4; cl17255
107806000566	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
107806000567	IMP binding site; other site
107806000568	dimer interface [polypeptide binding]; other site
107806000569	interdomain contacts; other site
107806000570	partial ornithine binding site; other site
107806000571	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
107806000572	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
107806000573	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
107806000574	catalytic site [active]
107806000575	subunit interface [polypeptide binding]; other site
107806000576	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
107806000577	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
107806000578	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
107806000579	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Region: lytB_ispH; cd13944
107806000580	Fe-S cluster binding site [ion binding]; other site
107806000581	substrate binding site [chemical binding]; other site
107806000582	catalytic site [active]
107806000583	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
107806000584	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
107806000585	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
107806000586	active site
107806000587	HIGH motif; other site
107806000588	KMSKS motif; other site
107806000589	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
107806000590	tRNA binding surface [nucleotide binding]; other site
107806000591	anticodon binding site; other site
107806000592	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
107806000593	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
107806000594	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
107806000595	active site
107806000596	Riboflavin kinase; Region: Flavokinase; smart00904
107806000597	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
107806000598	chaperone protein DnaJ; Provisional; Region: PRK10767
107806000599	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
107806000600	HSP70 interaction site [polypeptide binding]; other site
107806000601	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
107806000602	substrate binding site [polypeptide binding]; other site
107806000603	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
107806000604	Zn binding sites [ion binding]; other site
107806000605	dimer interface [polypeptide binding]; other site
107806000606	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
107806000607	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
107806000608	nucleotide binding site [chemical binding]; other site
107806000609	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
107806000610	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
107806000611	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
107806000612	NADH:ubiquinone oxidoreductase 27 kD subunit [Energy production and conversion]; Region: NuoC; COG0852
107806000613	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
107806000614	NADH-quinone oxidoreductase, E subunit; Region: nuoE_fam; TIGR01958
107806000615	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
107806000616	putative dimer interface [polypeptide binding]; other site
107806000617	[2Fe-2S] cluster binding site [ion binding]; other site
107806000618	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
107806000619	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
107806000620	SLBB domain; Region: SLBB; pfam10531
107806000621	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
107806000622	NADH dehydrogenase subunit G; Validated; Region: PRK08166
107806000623	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
107806000624	catalytic loop [active]
107806000625	iron binding site [ion binding]; other site
107806000626	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
107806000627	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
107806000628	[4Fe-4S] binding site [ion binding]; other site
107806000629	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
107806000630	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
107806000631	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
107806000632	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
107806000633	accessory Sec system protein Asp2; Region: acc_sec_asp2; TIGR03712
107806000634	NADH-ubiquinone/plastoquinone oxidoreductase chain 6; Region: Oxidored_q3; cl17265
107806000635	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
107806000636	proton-translocating NADH-quinone oxidoreductase, chain L; Region: NDH_I_L; TIGR01974
107806000637	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
107806000638	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
107806000639	proton-translocating NADH-quinone oxidoreductase, chain M; Region: NDH_I_M; TIGR01972
107806000640	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
107806000641	NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; Region: NuoN; COG1007
107806000642	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
107806000643	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
107806000644	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
107806000645	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
107806000646	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
107806000647	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
107806000648	active site
107806000649	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
107806000650	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
107806000651	peptide chain release factor 1; Validated; Region: prfA; PRK00591
107806000652	This domain is found in peptide chain release factors; Region: PCRF; smart00937
107806000653	RF-1 domain; Region: RF-1; pfam00472
107806000654	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
107806000655	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
107806000656	S-adenosylmethionine binding site [chemical binding]; other site
107806000657	hypothetical protein; Provisional; Region: PRK10941
107806000658	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
107806000659	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
107806000660	homodimer interface [polypeptide binding]; other site
107806000661	NAD binding pocket [chemical binding]; other site
107806000662	ATP binding pocket [chemical binding]; other site
107806000663	Mg binding site [ion binding]; other site
107806000664	active-site loop [active]
107806000665	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
107806000666	phosphate acetyltransferase; Reviewed; Region: PRK05632
107806000667	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
107806000668	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
107806000669	catalytic loop [active]
107806000670	iron binding site [ion binding]; other site
107806000671	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
107806000672	dimer interface [polypeptide binding]; other site
107806000673	putative radical transfer pathway; other site
107806000674	diiron center [ion binding]; other site
107806000675	tyrosyl radical; other site
107806000676	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
107806000677	ATP cone domain; Region: ATP-cone; pfam03477
107806000678	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
107806000679	DNA gyrase subunit A; Validated; Region: PRK05560
107806000680	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
107806000681	CAP-like domain; other site
107806000682	active site
107806000683	primary dimer interface [polypeptide binding]; other site
107806000684	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
107806000685	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
107806000686	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
107806000687	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
107806000688	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
107806000689	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
107806000690	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3416
107806000691	Uncharacterized protein conserved in bacteria (DUF2076); Region: DUF2076; pfam09849
107806000692	peroxidase; Provisional; Region: PRK15000
107806000693	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
107806000694	dimer interface [polypeptide binding]; other site
107806000695	decamer (pentamer of dimers) interface [polypeptide binding]; other site
107806000696	catalytic triad [active]
107806000697	peroxidatic and resolving cysteines [active]
107806000698	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
107806000699	ligand binding site [chemical binding]; other site
107806000700	active site
107806000701	UGI interface [polypeptide binding]; other site
107806000702	catalytic site [active]
107806000703	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
107806000704	dimer interface [polypeptide binding]; other site
107806000705	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
107806000706	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
107806000707	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
107806000708	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
107806000709	putative GSH binding site [chemical binding]; other site
107806000710	catalytic residues [active]
107806000711	ribonuclease T; Provisional; Region: PRK05168
107806000712	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
107806000713	active site
107806000714	catalytic site [active]
107806000715	substrate binding site [chemical binding]; other site
107806000716	superoxide dismutase; Provisional; Region: PRK10925
107806000717	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
107806000718	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
107806000719	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
107806000720	putative active site [active]
107806000721	catalytic residue [active]
107806000722	GTP-binding protein YchF; Reviewed; Region: PRK09601
107806000723	YchF GTPase; Region: YchF; cd01900
107806000724	G1 box; other site
107806000725	GTP/Mg2+ binding site [chemical binding]; other site
107806000726	Switch I region; other site
107806000727	G2 box; other site
107806000728	Switch II region; other site
107806000729	G3 box; other site
107806000730	G4 box; other site
107806000731	G5 box; other site
107806000732	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
107806000733	threonine synthase; Validated; Region: PRK09225
107806000734	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
107806000735	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
107806000736	catalytic residue [active]
107806000737	homoserine kinase; Provisional; Region: PRK01212
107806000738	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
107806000739	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
107806000740	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
107806000741	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
107806000742	putative catalytic residues [active]
107806000743	putative nucleotide binding site [chemical binding]; other site
107806000744	putative aspartate binding site [chemical binding]; other site
107806000745	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
107806000746	dimer interface [polypeptide binding]; other site
107806000747	putative threonine allosteric regulatory site; other site
107806000748	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
107806000749	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
107806000750	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
107806000751	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
107806000752	active site
107806000753	Pantoate-beta-alanine ligase; Region: PanC; cd00560
107806000754	active site
107806000755	ATP-binding site [chemical binding]; other site
107806000756	pantoate-binding site; other site
107806000757	HXXH motif; other site
107806000758	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
107806000759	oligomerization interface [polypeptide binding]; other site
107806000760	active site
107806000761	metal binding site [ion binding]; metal-binding site
107806000762	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
107806000763	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
107806000764	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
107806000765	dimerization interface 3.5A [polypeptide binding]; other site
107806000766	active site
107806000767	penicillin-binding protein 1b; Provisional; Region: PRK14850
107806000768	Bifunctional transglycosylase second domain; Region: UB2H; pfam14814
107806000769	Transglycosylase; Region: Transgly; pfam00912
107806000770	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
107806000771	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
107806000772	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
107806000773	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
107806000774	nucleotide binding region [chemical binding]; other site
107806000775	ATP-binding site [chemical binding]; other site
107806000776	SecA Wing and Scaffold domain; Region: SecA_SW; pfam07516
107806000777	SEC-C motif; Region: SEC-C; pfam02810
107806000778	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
107806000779	nudix motif; other site
107806000780	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
107806000781	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
107806000782	CoA-binding site [chemical binding]; other site
107806000783	ATP-binding [chemical binding]; other site
107806000784	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
107806000785	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
107806000786	active site
107806000787	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
107806000788	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
107806000789	dimer interface [polypeptide binding]; other site
107806000790	TPP-binding site [chemical binding]; other site
107806000791	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
107806000792	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
107806000793	E3 interaction surface; other site
107806000794	lipoyl attachment site [posttranslational modification]; other site
107806000795	e3 binding domain; Region: E3_binding; pfam02817
107806000796	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
107806000797	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
107806000798	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
107806000799	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
107806000800	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
107806000801	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
107806000802	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
107806000803	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
107806000804	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
107806000805	cell division protein FtsZ; Validated; Region: PRK09330
107806000806	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
107806000807	nucleotide binding site [chemical binding]; other site
107806000808	SulA interaction site; other site
107806000809	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
107806000810	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
107806000811	nucleotide binding site [chemical binding]; other site
107806000812	Cell division protein FtsA; Region: FtsA; pfam14450
107806000813	contains authentic frameshift; putative D-alanine--D-alanine ligase partially similar to protein DDLB_ECOLI SW:P07862
107806000814	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
107806000815	UDP-N-acetylmuramate-alanine ligase [Cell envelope biogenesis, outer membrane]; Region: MurC; COG0773
107806000816	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
107806000817	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
107806000818	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
107806000819	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
107806000820	active site
107806000821	homodimer interface [polypeptide binding]; other site
107806000822	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
107806000823	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
107806000824	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
107806000825	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
107806000826	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
107806000827	Mg++ binding site [ion binding]; other site
107806000828	putative catalytic motif [active]
107806000829	putative substrate binding site [chemical binding]; other site
107806000830	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
107806000831	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
107806000832	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
107806000833	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
107806000834	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
107806000835	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
107806000836	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
107806000837	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
107806000838	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
107806000839	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
107806000840	Cell division protein [Cell division and chromosome partitioning]; Region: FtsL; COG3116
107806000841	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
107806000842	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
107806000843	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
107806000844	putative valine binding site [chemical binding]; other site
107806000845	dimer interface [polypeptide binding]; other site
107806000846	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
107806000847	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
107806000848	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
107806000849	PYR/PP interface [polypeptide binding]; other site
107806000850	dimer interface [polypeptide binding]; other site
107806000851	TPP binding site [chemical binding]; other site
107806000852	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
107806000853	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
107806000854	TPP-binding site [chemical binding]; other site
107806000855	dimer interface [polypeptide binding]; other site
107806000856	contains authentic frameshift; putative hypothetical protein partially similar to protein APBE_ECOLI
107806000857	serine endoprotease; Provisional; Region: PRK10942
107806000858	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
107806000859	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
107806000860	protein binding site [polypeptide binding]; other site
107806000861	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
107806000862	protein binding site [polypeptide binding]; other site
107806000863	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
107806000864	Tetrahydrodipicolinate N-succinyltransferase N-terminal; Region: THDPS_N_2; pfam14805
107806000865	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
107806000866	trimer interface [polypeptide binding]; other site
107806000867	active site
107806000868	substrate binding site [chemical binding]; other site
107806000869	CoA binding site [chemical binding]; other site
107806000870	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
107806000871	active site
107806000872	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
107806000873	rRNA interaction site [nucleotide binding]; other site
107806000874	S8 interaction site; other site
107806000875	putative laminin-1 binding site; other site
107806000876	elongation factor Ts; Provisional; Region: tsf; PRK09377
107806000877	UBA/TS-N domain; Region: UBA; pfam00627
107806000878	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
107806000879	putative nucleotide binding site [chemical binding]; other site
107806000880	uridine monophosphate binding site [chemical binding]; other site
107806000881	homohexameric interface [polypeptide binding]; other site
107806000882	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
107806000883	hinge region; other site
107806000884	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
107806000885	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
107806000886	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
107806000887	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
107806000888	Cis (Z)-Isoprenyl Diphosphate Synthases; Region: Cis_IPPS; cd00475
107806000889	active site
107806000890	dimer interface [polypeptide binding]; other site
107806000891	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
107806000892	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
107806000893	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
107806000894	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
107806000895	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
107806000896	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
107806000897	Surface antigen; Region: Bac_surface_Ag; pfam01103
107806000898	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
107806000899	active site 2 [active]
107806000900	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
107806000901	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
107806000902	putative active site [active]
107806000903	putative PHP Thumb interface [polypeptide binding]; other site
107806000904	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
107806000905	Helix-hairpin-helix motif; Region: HHH_6; pfam14579
107806000906	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
107806000907	generic binding surface II; other site
107806000908	generic binding surface I; other site
107806000909	prolyl-tRNA synthetase; Provisional; Region: PRK09194
107806000910	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
107806000911	dimer interface [polypeptide binding]; other site
107806000912	motif 1; other site
107806000913	active site
107806000914	motif 2; other site
107806000915	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
107806000916	putative deacylase active site [active]
107806000917	motif 3; other site
107806000918	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
107806000919	anticodon binding site; other site
107806000920	flagellar biosynthetic protein FlhB; Region: flhB; TIGR00328
107806000921	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
107806000922	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
107806000923	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
107806000924	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
107806000925	active site
107806000926	HIGH motif; other site
107806000927	KMSK motif region; other site
107806000928	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
107806000929	tRNA binding surface [nucleotide binding]; other site
107806000930	anticodon binding site; other site
107806000931	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
107806000932	contains authentic frameshift; putative ribonuclease H partially similar to RNH_ECOLI SP:P00647
107806000933	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
107806000934	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
107806000935	active site
107806000936	catalytic site [active]
107806000937	substrate binding site [chemical binding]; other site
107806000938	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
107806000939	dimer interface [polypeptide binding]; other site
107806000940	active site
107806000941	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
107806000942	active site
107806000943	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
107806000944	dimer interface [polypeptide binding]; other site
107806000945	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
107806000946	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2914
107806000947	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
107806000948	SmpB-tmRNA interface; other site
107806000949	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
107806000950	nucleoside/Zn binding site; other site
107806000951	dimer interface [polypeptide binding]; other site
107806000952	catalytic motif [active]
107806000953	Phosphopantetheinyl transferase (holo-ACP synthase) [Lipid metabolism]; Region: AcpS; COG0736
107806000954	GTPase [General function prediction only]; Region: Era; COG1159
107806000955	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
107806000956	G1 box; other site
107806000957	GTP/Mg2+ binding site [chemical binding]; other site
107806000958	Switch I region; other site
107806000959	G2 box; other site
107806000960	Switch II region; other site
107806000961	G3 box; other site
107806000962	G4 box; other site
107806000963	G5 box; other site
107806000964	ribonuclease III; Reviewed; Region: rnc; PRK00102
107806000965	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
107806000966	dimerization interface [polypeptide binding]; other site
107806000967	active site
107806000968	metal binding site [ion binding]; metal-binding site
107806000969	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
107806000970	dsRNA binding site [nucleotide binding]; other site
107806000971	signal peptidase I; Provisional; Region: PRK10861
107806000972	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
107806000973	Catalytic site [active]
107806000974	GTP-binding protein LepA; Provisional; Region: PRK05433
107806000975	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
107806000976	G1 box; other site
107806000977	putative GEF interaction site [polypeptide binding]; other site
107806000978	GTP/Mg2+ binding site [chemical binding]; other site
107806000979	Switch I region; other site
107806000980	G2 box; other site
107806000981	G3 box; other site
107806000982	Switch II region; other site
107806000983	G4 box; other site
107806000984	G5 box; other site
107806000985	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
107806000986	Elongation Factor G, domain II; Region: EFG_II; pfam14492
107806000987	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
107806000988	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
107806000989	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
107806000990	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
107806000991	Ligand Binding Site [chemical binding]; other site
107806000992	Uncharacterized protein involved in purine metabolism [General function prediction only]; Region: COG2915
107806000993	adenylosuccinate lyase; Provisional; Region: PRK09285
107806000994	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
107806000995	tetramer interface [polypeptide binding]; other site
107806000996	active site
107806000997	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
107806000998	N-acetyl-D-glucosamine binding site [chemical binding]; other site
107806000999	catalytic residue [active]
107806001000	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
107806001001	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
107806001002	NAD binding site [chemical binding]; other site
107806001003	homotetramer interface [polypeptide binding]; other site
107806001004	homodimer interface [polypeptide binding]; other site
107806001005	substrate binding site [chemical binding]; other site
107806001006	active site
107806001007	exoribonuclease II; Provisional; Region: PRK05054
107806001008	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
107806001009	RNB domain; Region: RNB; pfam00773
107806001010	hypothetical protein; Provisional; Region: PRK11111
107806001011	Lipoate-protein ligase B [Coenzyme metabolism]; Region: LipB; COG0321
107806001012	lipoyl synthase; Provisional; Region: PRK05481
107806001013	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
107806001014	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
107806001015	active site
107806001016	dimer interface [polypeptide binding]; other site
107806001017	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
107806001018	dimerization interface [polypeptide binding]; other site
107806001019	active site
107806001020	Domain in histone-like proteins of HNS family; Region: HNS; cl19571
107806001021	DNA-binding protein H-NS [General function prediction only]; Region: Hns; COG2916
107806001022	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
107806001023	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
107806001024	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
107806001025	putative active site [active]
107806001026	catalytic site [active]
107806001027	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
107806001028	putative active site [active]
107806001029	catalytic site [active]
107806001030	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
107806001031	Intracellular septation protein A [Cell division and chromosome partitioning]; Region: COG2917
107806001032	Uncharacterized protein family (UPF0259); Region: UPF0259; pfam06790
107806001033	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
107806001034	substrate binding site [chemical binding]; other site
107806001035	active site
107806001036	catalytic residues [active]
107806001037	heterodimer interface [polypeptide binding]; other site
107806001038	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
107806001039	pyridoxal 5'-phosphate binding site [chemical binding]; other site
107806001040	catalytic residue [active]
107806001041	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
107806001042	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
107806001043	active site
107806001044	ribulose/triose binding site [chemical binding]; other site
107806001045	phosphate binding site [ion binding]; other site
107806001046	substrate (anthranilate) binding pocket [chemical binding]; other site
107806001047	product (indole) binding pocket [chemical binding]; other site
107806001048	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
107806001049	active site
107806001050	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
107806001051	anthranilate phosphoribosyltransferase; Region: trpD; TIGR01245
107806001052	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
107806001053	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
107806001054	EamA-like transporter family; Region: EamA; pfam00892
107806001055	EamA-like transporter family; Region: EamA; pfam00892
107806001056	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
107806001057	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
107806001058	RNA binding surface [nucleotide binding]; other site
107806001059	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
107806001060	probable active site [active]
107806001061	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
107806001062	putative inner membrane peptidase; Provisional; Region: PRK11778
107806001063	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
107806001064	tandem repeat interface [polypeptide binding]; other site
107806001065	oligomer interface [polypeptide binding]; other site
107806001066	active site residues [active]
107806001067	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
107806001068	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
107806001069	active site
107806001070	interdomain interaction site; other site
107806001071	putative metal-binding site [ion binding]; other site
107806001072	nucleotide binding site [chemical binding]; other site
107806001073	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
107806001074	domain I; other site
107806001075	DNA binding groove [nucleotide binding]
107806001076	phosphate binding site [ion binding]; other site
107806001077	domain II; other site
107806001078	domain III; other site
107806001079	nucleotide binding site [chemical binding]; other site
107806001080	catalytic site [active]
107806001081	domain IV; other site
107806001082	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
107806001083	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
107806001084	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
107806001085	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
107806001086	active site
107806001087	dimerization interface [polypeptide binding]; other site
107806001088	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
107806001089	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
107806001090	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
107806001091	FeS/SAM binding site; other site
107806001092	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
107806001093	1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Region: ispG_gcpE; TIGR00612
107806001094	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
107806001095	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
107806001096	dimer interface [polypeptide binding]; other site
107806001097	motif 1; other site
107806001098	active site
107806001099	motif 2; other site
107806001100	motif 3; other site
107806001101	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
107806001102	anticodon binding site; other site
107806001103	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
107806001104	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
107806001105	dimer interface [polypeptide binding]; other site
107806001106	active site
107806001107	glycine-pyridoxal phosphate binding site [chemical binding]; other site
107806001108	folate binding site [chemical binding]; other site
107806001109	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
107806001110	AAA domain; Region: AAA_26; pfam13500
107806001111	biotin synthase; Provisional; Region: PRK15108
107806001112	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
107806001113	FeS/SAM binding site; other site
107806001114	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
107806001115	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
107806001116	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
107806001117	inhibitor-cofactor binding pocket; inhibition site
107806001118	pyridoxal 5'-phosphate binding site [chemical binding]; other site
107806001119	catalytic residue [active]
107806001120	6-phosphogluconolactonase; Provisional; Region: PRK11028
107806001121	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
107806001122	DEAD-like helicases superfamily; Region: DEXDc; smart00487
107806001123	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
107806001124	ATP binding site [chemical binding]; other site
107806001125	putative Mg++ binding site [ion binding]; other site
107806001126	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
107806001127	nucleotide binding region [chemical binding]; other site
107806001128	ATP-binding site [chemical binding]; other site
107806001129	TRCF domain; Region: TRCF; pfam03461
107806001130	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
107806001131	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
107806001132	FtsX-like permease family; Region: FtsX; pfam02687
107806001133	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
107806001134	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
107806001135	Walker A/P-loop; other site
107806001136	ATP binding site [chemical binding]; other site
107806001137	Q-loop/lid; other site
107806001138	ABC transporter signature motif; other site
107806001139	Walker B; other site
107806001140	D-loop; other site
107806001141	H-loop/switch region; other site
107806001142	contains authentic frameshift; putative hypothetical 45.3 kDa protein similar to protein YCFW_ECOLI SW:P75958
107806001143	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
107806001144	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
107806001145	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
107806001146	flavodoxin FldA; Validated; Region: PRK09267
107806001147	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
107806001148	DNA photolyase; Region: DNA_photolyase; pfam00875
107806001149	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
107806001150	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
107806001151	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
107806001152	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
107806001153	TPP-binding site [chemical binding]; other site
107806001154	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
107806001155	2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); Region: sucB; TIGR01347
107806001156	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
107806001157	E3 interaction surface; other site
107806001158	lipoyl attachment site [posttranslational modification]; other site
107806001159	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
107806001160	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
107806001161	catalytic core [active]
107806001162	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
107806001163	active site
107806001164	ADP/pyrophosphate binding site [chemical binding]; other site
107806001165	dimerization interface [polypeptide binding]; other site
107806001166	allosteric effector site; other site
107806001167	fructose-1,6-bisphosphate binding site; other site
107806001168	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
107806001169	amphipathic channel; other site
107806001170	Asn-Pro-Ala signature motifs; other site
107806001171	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
107806001172	substrate binding site [chemical binding]; other site
107806001173	dimer interface [polypeptide binding]; other site
107806001174	catalytic triad [active]
107806001175	Beta subunit of integration host factor (IHFB); Region: IHF_B; cd13836
107806001176	dimer interface [polypeptide binding]; other site
107806001177	DNA binding site [nucleotide binding]
107806001178	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
107806001179	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
107806001180	RNA binding site [nucleotide binding]; other site
107806001181	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
107806001182	RNA binding site [nucleotide binding]; other site
107806001183	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
107806001184	RNA binding site [nucleotide binding]; other site
107806001185	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
107806001186	RNA binding site [nucleotide binding]; other site
107806001187	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
107806001188	RNA binding site [nucleotide binding]; other site
107806001189	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
107806001190	RNA binding site [nucleotide binding]; other site
107806001191	contains authentic frameshift; putative cytidylate kinase protein is similar to KCY_ECOLI SP:P23863
107806001192	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
107806001193	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
107806001194	hinge; other site
107806001195	active site
107806001196	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
107806001197	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
107806001198	catalytic residue [active]
107806001199	seryl-tRNA synthetase; Provisional; Region: PRK05431
107806001200	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
107806001201	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
107806001202	dimer interface [polypeptide binding]; other site
107806001203	active site
107806001204	motif 1; other site
107806001205	motif 2; other site
107806001206	motif 3; other site
107806001207	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
107806001208	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
107806001209	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
107806001210	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
107806001211	rRNA binding site [nucleotide binding]; other site
107806001212	predicted 30S ribosome binding site; other site
107806001213	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
107806001214	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
107806001215	dimer interface [polypeptide binding]; other site
107806001216	anticodon binding site; other site
107806001217	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
107806001218	homodimer interface [polypeptide binding]; other site
107806001219	motif 1; other site
107806001220	active site
107806001221	motif 2; other site
107806001222	GAD domain; Region: GAD; pfam02938
107806001223	motif 3; other site
107806001224	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
107806001225	ABC-ATPase subunit  interface; other site
107806001226	dimer interface [polypeptide binding]; other site
107806001227	putative PBP binding regions; other site
107806001228	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
107806001229	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
107806001230	Walker A/P-loop; other site
107806001231	ATP binding site [chemical binding]; other site
107806001232	Q-loop/lid; other site
107806001233	ABC transporter signature motif; other site
107806001234	Walker B; other site
107806001235	D-loop; other site
107806001236	H-loop/switch region; other site
107806001237	pyruvate kinase; Provisional; Region: PRK05826
107806001238	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
107806001239	domain interfaces; other site
107806001240	active site
107806001241	Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Region: Zwf; COG0364
107806001242	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
107806001243	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
107806001244	heat shock protein HtpX; Provisional; Region: PRK05457
107806001245	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
107806001246	DNA-binding site [nucleotide binding]; DNA binding site
107806001247	RNA-binding motif; other site
107806001248	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
107806001249	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
107806001250	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
107806001251	Transporter associated domain; Region: CorC_HlyC; smart01091
107806001252	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
107806001253	Glycoprotease family; Region: Peptidase_M22; pfam00814
107806001254	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
107806001255	cell division inhibitor MinD; Provisional; Region: PRK10818
107806001256	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
107806001257	P-loop; other site
107806001258	ADP binding residues [chemical binding]; other site
107806001259	Switch I; other site
107806001260	Switch II; other site
107806001261	septum formation inhibitor; Reviewed; Region: minC; PRK03511
107806001262	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
107806001263	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
107806001264	16S RNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; Region: RsmC; COG2813
107806001265	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
107806001266	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
107806001267	S-adenosylmethionine binding site [chemical binding]; other site
107806001268	outer membrane protein A; Reviewed; Region: PRK10808
107806001269	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
107806001270	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
107806001271	ligand binding site [chemical binding]; other site
107806001272	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
107806001273	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
107806001274	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
107806001275	active site
107806001276	substrate binding pocket [chemical binding]; other site
107806001277	dimer interface [polypeptide binding]; other site
107806001278	Flagellar biosynthesis/type III secretory pathway chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3418
107806001279	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
107806001280	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
107806001281	flagellar basal-body rod protein FlgB; Region: FlgB; TIGR01396
107806001282	flagellar basal body rod protein FlgB; Provisional; Region: flgB; cl19173
107806001283	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgC; COG1558
107806001284	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
107806001285	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
107806001286	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
107806001287	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
107806001288	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
107806001289	Flagellar hook protein FlgE [Cell motility and secretion]; Region: FlgE; COG1749
107806001290	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
107806001291	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
107806001292	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
107806001293	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
107806001294	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
107806001295	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
107806001296	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
107806001297	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
107806001298	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
107806001299	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
107806001300	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
107806001301	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
107806001302	Flagellar hook-associated protein [Cell motility and secretion]; Region: FlgK; COG1256
107806001303	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
107806001304	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
107806001305	homodimer interface [polypeptide binding]; other site
107806001306	oligonucleotide binding site [chemical binding]; other site
107806001307	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
107806001308	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
107806001309	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
107806001310	RNA binding surface [nucleotide binding]; other site
107806001311	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
107806001312	active site
107806001313	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
107806001314	contains authentic frameshift; putative malonyl CoA-acyl carrier protein transacylase similar to FABD_ECOLI SW:P25715
107806001315	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
107806001316	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
107806001317	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
107806001318	NAD(P) binding site [chemical binding]; other site
107806001319	active site
107806001320	acyl carrier protein; Provisional; Region: acpP; PRK00982
107806001321	thymidylate kinase; Validated; Region: tmk; PRK00698
107806001322	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
107806001323	TMP-binding site; other site
107806001324	ATP-binding site [chemical binding]; other site
107806001325	DNA polymerase III subunit delta'; Validated; Region: PRK07993
107806001326	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
107806001327	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
107806001328	active site
107806001329	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
107806001330	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
107806001331	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
107806001332	active site turn [active]
107806001333	phosphorylation site [posttranslational modification]
107806001334	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
107806001335	nucleotide binding site/active site [active]
107806001336	HIT family signature motif; other site
107806001337	catalytic residue [active]
107806001338	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
107806001339	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
107806001340	trimer interface [polypeptide binding]; other site
107806001341	eyelet of channel; other site
107806001342	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
107806001343	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
107806001344	putative dimer interface [polypeptide binding]; other site
107806001345	putative anticodon binding site; other site
107806001346	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
107806001347	homodimer interface [polypeptide binding]; other site
107806001348	motif 1; other site
107806001349	motif 2; other site
107806001350	active site
107806001351	motif 3; other site
107806001352	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
107806001353	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
107806001354	active site
107806001355	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
107806001356	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
107806001357	active site
107806001358	catalytic residues [active]
107806001359	FMN binding site [chemical binding]; other site
107806001360	quinone interaction residues [chemical binding]; other site
107806001361	substrate binding site [chemical binding]; other site
107806001362	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
107806001363	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
107806001364	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
107806001365	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
107806001366	S-adenosylmethionine binding site [chemical binding]; other site
107806001367	ABC transporter ATPase component; Reviewed; Region: PRK11147
107806001368	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
107806001369	ABC transporter; Region: ABC_tran_2; pfam12848
107806001370	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
107806001371	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
107806001372	Q-loop/lid; other site
107806001373	ABC transporter signature motif; other site
107806001374	Walker B; other site
107806001375	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
107806001376	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
107806001377	active site residue [active]
107806001378	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
107806001379	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
107806001380	active site
107806001381	HIGH motif; other site
107806001382	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
107806001383	KMSKS motif; other site
107806001384	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
107806001385	tRNA binding surface [nucleotide binding]; other site
107806001386	anticodon binding site; other site
107806001387	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
107806001388	multifunctional aminopeptidase A; Provisional; Region: PRK00913
107806001389	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
107806001390	interface (dimer of trimers) [polypeptide binding]; other site
107806001391	Substrate-binding/catalytic site; other site
107806001392	Zn-binding sites [ion binding]; other site
107806001393	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
107806001394	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
107806001395	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
107806001396	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
107806001397	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
107806001398	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
107806001399	Aspartate carbamoyltransferase, regulatory subunit [Nucleotide transport and metabolism]; Region: PyrI; COG1781
107806001400	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
107806001401	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
107806001402	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
107806001403	homotrimer interaction site [polypeptide binding]; other site
107806001404	putative active site [active]
107806001405	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
107806001406	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
107806001407	ATP binding site [chemical binding]; other site
107806001408	Mg++ binding site [ion binding]; other site
107806001409	motif III; other site
107806001410	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
107806001411	nucleotide binding region [chemical binding]; other site
107806001412	ATP-binding site [chemical binding]; other site
107806001413	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
107806001414	putative RNA binding site [nucleotide binding]; other site
107806001415	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
107806001416	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
107806001417	RNase E interface [polypeptide binding]; other site
107806001418	trimer interface [polypeptide binding]; other site
107806001419	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
107806001420	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
107806001421	RNase E interface [polypeptide binding]; other site
107806001422	trimer interface [polypeptide binding]; other site
107806001423	active site
107806001424	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
107806001425	putative nucleic acid binding region [nucleotide binding]; other site
107806001426	G-X-X-G motif; other site
107806001427	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
107806001428	RNA binding site [nucleotide binding]; other site
107806001429	domain interface; other site
107806001430	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
107806001431	16S/18S rRNA binding site [nucleotide binding]; other site
107806001432	S13e-L30e interaction site [polypeptide binding]; other site
107806001433	25S rRNA binding site [nucleotide binding]; other site
107806001434	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
107806001435	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
107806001436	RNA binding site [nucleotide binding]; other site
107806001437	active site
107806001438	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
107806001439	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
107806001440	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
107806001441	translation initiation factor IF-2; Validated; Region: infB; PRK05306
107806001442	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
107806001443	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
107806001444	G1 box; other site
107806001445	putative GEF interaction site [polypeptide binding]; other site
107806001446	GTP/Mg2+ binding site [chemical binding]; other site
107806001447	Switch I region; other site
107806001448	G2 box; other site
107806001449	G3 box; other site
107806001450	Switch II region; other site
107806001451	G4 box; other site
107806001452	G5 box; other site
107806001453	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
107806001454	Translation-initiation factor 2; Region: IF-2; pfam11987
107806001455	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
107806001456	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
107806001457	NusA N-terminal domain; Region: NusA_N; pfam08529
107806001458	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
107806001459	RNA binding site [nucleotide binding]; other site
107806001460	homodimer interface [polypeptide binding]; other site
107806001461	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
107806001462	G-X-X-G motif; other site
107806001463	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
107806001464	G-X-X-G motif; other site
107806001465	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
107806001466	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
107806001467	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
107806001468	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
107806001469	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
107806001470	active site
107806001471	substrate binding site [chemical binding]; other site
107806001472	metal binding site [ion binding]; metal-binding site
107806001473	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
107806001474	FtsH Extracellular; Region: FtsH_ext; pfam06480
107806001475	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
107806001476	Walker A motif; other site
107806001477	ATP binding site [chemical binding]; other site
107806001478	Walker B motif; other site
107806001479	arginine finger; other site
107806001480	Peptidase family M41; Region: Peptidase_M41; pfam01434
107806001481	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
107806001482	S-adenosylmethionine binding site [chemical binding]; other site
107806001483	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
107806001484	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
107806001485	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
107806001486	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
107806001487	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Region: EPSP_synthase; pfam00275
107806001488	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
107806001489	hinge; other site
107806001490	active site
107806001491	Ribosomal protein L21 [Translation, ribosomal structure and biogenesis]; Region: RplU; COG0261
107806001492	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
107806001493	Obg family GTPase CgtA; Region: Obg_CgtA; TIGR02729
107806001494	GTP1/OBG; Region: GTP1_OBG; pfam01018
107806001495	Obg GTPase; Region: Obg; cd01898
107806001496	G1 box; other site
107806001497	GTP/Mg2+ binding site [chemical binding]; other site
107806001498	Switch I region; other site
107806001499	G2 box; other site
107806001500	G3 box; other site
107806001501	Switch II region; other site
107806001502	G4 box; other site
107806001503	G5 box; other site
107806001504	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
107806001505	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
107806001506	23S rRNA interface [nucleotide binding]; other site
107806001507	L3 interface [polypeptide binding]; other site
107806001508	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
107806001509	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
107806001510	Prephenate dehydratase; Region: PDT; pfam00800
107806001511	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
107806001512	putative L-Phe binding site [chemical binding]; other site
107806001513	signal recognition particle protein; Provisional; Region: PRK10867
107806001514	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
107806001515	SRP54-type protein, GTPase domain; Region: SRP54; smart00962
107806001516	Signal peptide binding domain; Region: SRP_SPB; pfam02978
107806001517	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
107806001518	RimM protein, required for 16S rRNA processing [Translation, ribosomal structure and biogenesis]; Region: RimM; COG0806
107806001519	RimM N-terminal domain; Region: RimM; pfam01782
107806001520	PRC-barrel domain; Region: PRC; pfam05239
107806001521	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
107806001522	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
107806001523	Putative modulator of DNA gyrase; Region: PmbA_TldD; cl19356
107806001524	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
107806001525	trimer interface [polypeptide binding]; other site
107806001526	active site
107806001527	dimer interface [polypeptide binding]; other site
107806001528	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
107806001529	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
107806001530	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
107806001531	RNA binding surface [nucleotide binding]; other site
107806001532	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
107806001533	active site
107806001534	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
107806001535	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
107806001536	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
107806001537	motif 1; other site
107806001538	active site
107806001539	motif 2; other site
107806001540	motif 3; other site
107806001541	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
107806001542	carbon storage regulator; Provisional; Region: PRK01712
107806001543	glutamate--cysteine ligase; Region: glu_cys_ligase; TIGR01434
107806001544	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
107806001545	S-adenosylmethionine synthetase; Validated; Region: PRK05250
107806001546	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
107806001547	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
107806001548	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
107806001549	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
107806001550	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
107806001551	tetramer (dimer of dimers) interface [polypeptide binding]; other site
107806001552	active site
107806001553	dimer interface [polypeptide binding]; other site
107806001554	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
107806001555	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
107806001556	active site
107806001557	nucleotide binding site [chemical binding]; other site
107806001558	HIGH motif; other site
107806001559	KMSKS motif; other site
107806001560	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
107806001561	CTP synthetase; Validated; Region: pyrG; PRK05380
107806001562	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
107806001563	Catalytic site [active]
107806001564	active site
107806001565	UTP binding site [chemical binding]; other site
107806001566	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
107806001567	active site
107806001568	putative oxyanion hole; other site
107806001569	catalytic triad [active]
107806001570	enolase; Provisional; Region: eno; PRK00077
107806001571	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
107806001572	dimer interface [polypeptide binding]; other site
107806001573	metal binding site [ion binding]; metal-binding site
107806001574	substrate binding pocket [chemical binding]; other site
107806001575	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
107806001576	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
107806001577	Peptidase family M23; Region: Peptidase_M23; pfam01551
107806001578	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
107806001579	homotrimer interaction site [polypeptide binding]; other site
107806001580	zinc binding site [ion binding]; other site
107806001581	CDP-binding sites; other site
107806001582	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
107806001583	substrate binding site; other site
107806001584	dimer interface; other site
107806001585	Septum formation initiator; Region: DivIC; cl17659
107806001586	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
107806001587	ligand-binding site [chemical binding]; other site
107806001588	GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895
107806001589	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
107806001590	CysD dimerization site [polypeptide binding]; other site
107806001591	G1 box; other site
107806001592	putative GEF interaction site [polypeptide binding]; other site
107806001593	GTP/Mg2+ binding site [chemical binding]; other site
107806001594	Switch I region; other site
107806001595	G2 box; other site
107806001596	G3 box; other site
107806001597	Switch II region; other site
107806001598	G4 box; other site
107806001599	G5 box; other site
107806001600	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
107806001601	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
107806001602	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
107806001603	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
107806001604	Active Sites [active]
107806001605	siroheme synthase; Provisional; Region: cysG; PRK10637
107806001606	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
107806001607	Sirohaem synthase dimerization region; Region: CysG_dimeriser; pfam10414
107806001608	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
107806001609	active site
107806001610	SAM binding site [chemical binding]; other site
107806001611	homodimer interface [polypeptide binding]; other site
107806001612	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
107806001613	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
107806001614	Active Sites [active]
107806001615	sulfite reductase (NADPH) hemoprotein, beta-component; Region: CysI; TIGR02041
107806001616	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
107806001617	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
107806001618	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
107806001619	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
107806001620	sulfite reductase [NADPH] flavoprotein, alpha-component; Region: cysJ; TIGR01931
107806001621	Flavodoxin; Region: Flavodoxin_1; pfam00258
107806001622	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
107806001623	FAD binding pocket [chemical binding]; other site
107806001624	FAD binding motif [chemical binding]; other site
107806001625	catalytic residues [active]
107806001626	NAD binding pocket [chemical binding]; other site
107806001627	phosphate binding motif [ion binding]; other site
107806001628	beta-alpha-beta structure motif; other site
107806001629	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
107806001630	MutS domain I; Region: MutS_I; pfam01624
107806001631	MutS domain II; Region: MutS_II; pfam05188
107806001632	MutS domain III; Region: MutS_III; pfam05192
107806001633	MutS domain V; Region: MutS_V; pfam00488
107806001634	Walker A/P-loop; other site
107806001635	ATP binding site [chemical binding]; other site
107806001636	Q-loop/lid; other site
107806001637	ABC transporter signature motif; other site
107806001638	Walker B; other site
107806001639	D-loop; other site
107806001640	H-loop/switch region; other site
107806001641	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
107806001642	catalytic residues [active]
107806001643	hinge region; other site
107806001644	alpha helical domain; other site
107806001645	5'-3' exonuclease; Provisional; Region: PRK14976
107806001646	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
107806001647	active site
107806001648	metal binding site 1 [ion binding]; metal-binding site
107806001649	putative 5' ssDNA interaction site; other site
107806001650	metal binding site 3; metal-binding site
107806001651	metal binding site 2 [ion binding]; metal-binding site
107806001652	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
107806001653	putative DNA binding site [nucleotide binding]; other site
107806001654	putative metal binding site [ion binding]; other site
107806001655	Predicted GTPase [General function prediction only]; Region: COG0218
107806001656	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
107806001657	G1 box; other site
107806001658	GTP/Mg2+ binding site [chemical binding]; other site
107806001659	Switch I region; other site
107806001660	G2 box; other site
107806001661	G3 box; other site
107806001662	Switch II region; other site
107806001663	G4 box; other site
107806001664	G5 box; other site
107806001665	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
107806001666	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
107806001667	G1 box; other site
107806001668	putative GEF interaction site [polypeptide binding]; other site
107806001669	GTP/Mg2+ binding site [chemical binding]; other site
107806001670	Switch I region; other site
107806001671	G2 box; other site
107806001672	G3 box; other site
107806001673	Switch II region; other site
107806001674	G4 box; other site
107806001675	G5 box; other site
107806001676	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
107806001677	Elongation Factor G, domain II; Region: EFG_II; pfam14492
107806001678	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
107806001679	Guanylate kinase; Region: Guanylate_kin; pfam00625
107806001680	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
107806001681	catalytic site [active]
107806001682	G-X2-G-X-G-K; other site
107806001683	putative global regulator; Reviewed; Region: PRK09559
107806001684	Aminomethyltransferase folate-binding domain; Region: GCV_T; cl01893
107806001685	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
107806001686	peptide chain release factor 2; Validated; Region: prfB; PRK00578
107806001687	This domain is found in peptide chain release factors; Region: PCRF; smart00937
107806001688	RF-1 domain; Region: RF-1; pfam00472
107806001689	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
107806001690	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
107806001691	dimer interface [polypeptide binding]; other site
107806001692	putative anticodon binding site; other site
107806001693	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
107806001694	motif 1; other site
107806001695	active site
107806001696	motif 2; other site
107806001697	motif 3; other site
107806001698	diaminopimelate decarboxylase; Provisional; Region: PRK11165
107806001699	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
107806001700	active site
107806001701	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
107806001702	substrate binding site [chemical binding]; other site
107806001703	catalytic residues [active]
107806001704	dimer interface [polypeptide binding]; other site
107806001705	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
107806001706	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
107806001707	dimerization interface [polypeptide binding]; other site
107806001708	active site
107806001709	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
107806001710	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
107806001711	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
107806001712	FeS/SAM binding site; other site
107806001713	TRAM domain; Region: TRAM; pfam01938
107806001714	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG0319
107806001715	Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535
107806001716	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
107806001717	Transporter associated domain; Region: CorC_HlyC; smart01091
107806001718	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
107806001719	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
107806001720	active site
107806001721	HIGH motif; other site
107806001722	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
107806001723	KMSKS motif; other site
107806001724	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
107806001725	tRNA binding surface [nucleotide binding]; other site
107806001726	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
107806001727	DNA polymerase III, delta subunit; Region: holA; TIGR01128
107806001728	Processivity clamp loader gamma complex DNA pol III C-term; Region: DNA_pol3_delt_C; pfam14840
107806001729	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
107806001730	active site
107806001731	(T/H)XGH motif; other site
107806001732	sulfur transfer protein SirA; Reviewed; Region: PRK00299
107806001733	CPxP  motif; other site
107806001734	aspartate-semialdehyde dehydrogenase, gamma-proteobacterial; Region: asd_gamma; TIGR01745
107806001735	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
107806001736	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
107806001737	putative antibiotic transporter; Provisional; Region: PRK10739
107806001738	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
107806001739	substrate binding site [chemical binding]; other site
107806001740	hinge regions; other site
107806001741	ADP binding site [chemical binding]; other site
107806001742	catalytic site [active]
107806001743	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
107806001744	active site
107806001745	intersubunit interface [polypeptide binding]; other site
107806001746	zinc binding site [ion binding]; other site
107806001747	Na+ binding site [ion binding]; other site
107806001748	mechanosensitive channel MscS; Provisional; Region: PRK10334
107806001749	Conserved TM helix; Region: TM_helix; pfam05552
107806001750	Mechanosensitive ion channel; Region: MS_channel; pfam00924
107806001751	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
107806001752	Exodeoxyribonuclease V, gamma subunit; Region: Exonuc_V_gamma; pfam04257
107806001753	exodeoxyribonuclease V, beta subunit; Region: recB; TIGR00609
107806001754	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; cl19402
107806001755	exodeoxyribonuclease V, alpha subunit; Region: recD; TIGR01447
107806001756	AAA domain; Region: AAA_30; pfam13604
107806001757	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
107806001758	N-acetylglutamate synthase; Validated; Region: PRK05279
107806001759	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
107806001760	putative feedback inhibition sensing region; other site
107806001761	putative nucleotide binding site [chemical binding]; other site
107806001762	putative substrate binding site [chemical binding]; other site
107806001763	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
107806001764	Coenzyme A binding pocket [chemical binding]; other site
107806001765	murein transglycosylase A; Provisional; Region: mltA; PRK11162
107806001766	MltA specific insert domain; Region: MltA; smart00925
107806001767	3D domain; Region: 3D; pfam06725
107806001768	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
107806001769	homopentamer interface [polypeptide binding]; other site
107806001770	active site
107806001771	thiamine-monophosphate kinase; Region: thiL; TIGR01379
107806001772	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
107806001773	ATP binding site [chemical binding]; other site
107806001774	dimerization interface [polypeptide binding]; other site
107806001775	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
107806001776	catalytic motif [active]
107806001777	Zn binding site [ion binding]; other site
107806001778	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
107806001779	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
107806001780	putative RNA binding site [nucleotide binding]; other site
107806001781	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
107806001782	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
107806001783	TPP-binding site; other site
107806001784	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
107806001785	PYR/PP interface [polypeptide binding]; other site
107806001786	dimer interface [polypeptide binding]; other site
107806001787	TPP binding site [chemical binding]; other site
107806001788	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
107806001789	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
107806001790	substrate binding pocket [chemical binding]; other site
107806001791	chain length determination region; other site
107806001792	substrate-Mg2+ binding site; other site
107806001793	catalytic residues [active]
107806001794	aspartate-rich region 1; other site
107806001795	active site lid residues [active]
107806001796	aspartate-rich region 2; other site
107806001797	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
107806001798	Major Facilitator Superfamily; Region: MFS_1; pfam07690
107806001799	putative substrate translocation pore; other site
107806001800	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
107806001801	Protoheme IX farnesyltransferase; Region: PT_UbiA_Cox10; cd13957
107806001802	putative active site [active]
107806001803	cytochrome o ubiquinol oxidase subunit IV; Region: CyoD; TIGR02847
107806001804	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
107806001805	Subunit I/III interface [polypeptide binding]; other site
107806001806	Subunit III/IV interface [polypeptide binding]; other site
107806001807	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
107806001808	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
107806001809	D-pathway; other site
107806001810	Putative ubiquinol binding site [chemical binding]; other site
107806001811	Low-spin heme (heme b) binding site [chemical binding]; other site
107806001812	Putative water exit pathway; other site
107806001813	Binuclear center (heme o3/CuB) [ion binding]; other site
107806001814	K-pathway; other site
107806001815	Putative proton exit pathway; other site
107806001816	cytochrome o ubiquinol oxidase subunit II; Region: CyoA; TIGR01433
107806001817	The cupredoxin domain of Ubiquinol oxidase subunit II; Region: CuRO_UO_II; cd04212
107806001818	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
107806001819	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
107806001820	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) [Posttranslational modification, protein turnover, chaperones]; Region: Tig; COG0544
107806001821	Bacterial trigger factor protein (TF); Region: Trigger_N; pfam05697
107806001822	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
107806001823	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
107806001824	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
107806001825	oligomer interface [polypeptide binding]; other site
107806001826	active site residues [active]
107806001827	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
107806001828	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
107806001829	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
107806001830	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
107806001831	Walker A motif; other site
107806001832	ATP binding site [chemical binding]; other site
107806001833	Walker B motif; other site
107806001834	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
107806001835	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
107806001836	ATP-dependent protease La (LON) domain; Region: LON; pfam02190
107806001837	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
107806001838	Walker A motif; other site
107806001839	ATP binding site [chemical binding]; other site
107806001840	Walker B motif; other site
107806001841	arginine finger; other site
107806001842	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
107806001843	periplasmic folding chaperone; Provisional; Region: PRK10788
107806001844	SurA N-terminal domain; Region: SurA_N_3; cl07813
107806001845	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
107806001846	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
107806001847	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
107806001848	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
107806001849	Walker A/P-loop; other site
107806001850	ATP binding site [chemical binding]; other site
107806001851	Q-loop/lid; other site
107806001852	ABC transporter signature motif; other site
107806001853	Walker B; other site
107806001854	D-loop; other site
107806001855	H-loop/switch region; other site
107806001856	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
107806001857	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
107806001858	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
107806001859	Walker A/P-loop; other site
107806001860	ATP binding site [chemical binding]; other site
107806001861	Q-loop/lid; other site
107806001862	ABC transporter signature motif; other site
107806001863	Walker B; other site
107806001864	D-loop; other site
107806001865	H-loop/switch region; other site
107806001866	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14961
107806001867	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
107806001868	Walker A motif; other site
107806001869	ATP binding site [chemical binding]; other site
107806001870	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944
107806001871	Walker B motif; other site
107806001872	arginine finger; other site
107806001873	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
107806001874	hypothetical protein; Validated; Region: PRK00153
107806001875	heat shock protein 90; Provisional; Region: PRK05218
107806001876	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
107806001877	ATP binding site [chemical binding]; other site
107806001878	Mg2+ binding site [ion binding]; other site
107806001879	G-X-G motif; other site
107806001880	Hsp90 protein; Region: HSP90; pfam00183
107806001881	adenylate kinase; Reviewed; Region: adk; PRK00279
107806001882	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
107806001883	AMP-binding site [chemical binding]; other site
107806001884	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
107806001885	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
107806001886	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
107806001887	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
107806001888	homodimer interface [polypeptide binding]; other site
107806001889	NADP binding site [chemical binding]; other site
107806001890	substrate binding site [chemical binding]; other site
107806001891	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
107806001892	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
107806001893	active site
107806001894	HIGH motif; other site
107806001895	KMSKS motif; other site
107806001896	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
107806001897	tRNA binding surface [nucleotide binding]; other site
107806001898	anticodon binding site; other site
107806001899	hypothetical protein; Provisional; Region: PRK04998
107806001900	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
107806001901	DNA-binding site [nucleotide binding]; DNA binding site
107806001902	RNA-binding motif; other site
107806001903	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
107806001904	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
107806001905	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
107806001906	shikimate binding site; other site
107806001907	NAD(P) binding site [chemical binding]; other site
107806001908	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
107806001909	Uncharacterized protein conserved in bacteria [Function unknown]; Region: Smg; COG2922
107806001910	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
107806001911	active site
107806001912	catalytic residues [active]
107806001913	metal binding site [ion binding]; metal-binding site
107806001914	Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; Region: Fmt; COG0223
107806001915	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
107806001916	putative active site [active]
107806001917	substrate binding site [chemical binding]; other site
107806001918	putative cosubstrate binding site; other site
107806001919	catalytic site [active]
107806001920	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
107806001921	substrate binding site [chemical binding]; other site
107806001922	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
107806001923	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
107806001924	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
107806001925	alphaNTD homodimer interface [polypeptide binding]; other site
107806001926	alphaNTD - beta interaction site [polypeptide binding]; other site
107806001927	alphaNTD - beta' interaction site [polypeptide binding]; other site
107806001928	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
107806001929	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
107806001930	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
107806001931	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
107806001932	RNA binding surface [nucleotide binding]; other site
107806001933	30S ribosomal protein S11; Validated; Region: PRK05309
107806001934	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
107806001935	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
107806001936	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
107806001937	SecY translocase; Region: SecY; pfam00344
107806001938	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
107806001939	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
107806001940	23S rRNA binding site [nucleotide binding]; other site
107806001941	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
107806001942	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
107806001943	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
107806001944	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
107806001945	5S rRNA interface [nucleotide binding]; other site
107806001946	23S rRNA interface [nucleotide binding]; other site
107806001947	L5 interface [polypeptide binding]; other site
107806001948	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
107806001949	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
107806001950	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
107806001951	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
107806001952	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
107806001953	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
107806001954	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
107806001955	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
107806001956	RNA binding site [nucleotide binding]; other site
107806001957	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
107806001958	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
107806001959	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
107806001960	putative translocon interaction site; other site
107806001961	23S rRNA interface [nucleotide binding]; other site
107806001962	signal recognition particle (SRP54) interaction site; other site
107806001963	L23 interface [polypeptide binding]; other site
107806001964	trigger factor interaction site; other site
107806001965	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
107806001966	23S rRNA interface [nucleotide binding]; other site
107806001967	5S rRNA interface [nucleotide binding]; other site
107806001968	putative antibiotic binding site [chemical binding]; other site
107806001969	L25 interface [polypeptide binding]; other site
107806001970	L27 interface [polypeptide binding]; other site
107806001971	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
107806001972	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
107806001973	G-X-X-G motif; other site
107806001974	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
107806001975	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
107806001976	protein-rRNA interface [nucleotide binding]; other site
107806001977	putative translocon binding site; other site
107806001978	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
107806001979	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
107806001980	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
107806001981	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
107806001982	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
107806001983	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
107806001984	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
107806001985	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
107806001986	elongation factor Tu; Reviewed; Region: PRK00049
107806001987	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
107806001988	G1 box; other site
107806001989	GEF interaction site [polypeptide binding]; other site
107806001990	GTP/Mg2+ binding site [chemical binding]; other site
107806001991	Switch I region; other site
107806001992	G2 box; other site
107806001993	G3 box; other site
107806001994	Switch II region; other site
107806001995	G4 box; other site
107806001996	G5 box; other site
107806001997	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
107806001998	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
107806001999	Antibiotic Binding Site [chemical binding]; other site
107806002000	elongation factor G; Reviewed; Region: PRK00007
107806002001	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
107806002002	G1 box; other site
107806002003	putative GEF interaction site [polypeptide binding]; other site
107806002004	GTP/Mg2+ binding site [chemical binding]; other site
107806002005	Switch I region; other site
107806002006	G2 box; other site
107806002007	G3 box; other site
107806002008	Switch II region; other site
107806002009	G4 box; other site
107806002010	G5 box; other site
107806002011	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
107806002012	Elongation Factor G, domain II; Region: EFG_II; pfam14492
107806002013	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
107806002014	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
107806002015	30S ribosomal protein S7; Validated; Region: PRK05302
107806002016	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
107806002017	S17 interaction site [polypeptide binding]; other site
107806002018	S8 interaction site; other site
107806002019	16S rRNA interaction site [nucleotide binding]; other site
107806002020	streptomycin interaction site [chemical binding]; other site
107806002021	23S rRNA interaction site [nucleotide binding]; other site
107806002022	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
107806002023	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
107806002024	sulfur relay protein TusC; Validated; Region: PRK00211
107806002025	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
107806002026	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
107806002027	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
107806002028	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
107806002029	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
107806002030	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
107806002031	inhibitor-cofactor binding pocket; inhibition site
107806002032	pyridoxal 5'-phosphate binding site [chemical binding]; other site
107806002033	catalytic residue [active]
107806002034	putative transporter; Provisional; Region: PRK03699
107806002035	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
107806002036	putative substrate translocation pore; other site
107806002037	tryptophanyl-tRNA synthetase; Reviewed; Region: PRK00927
107806002038	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
107806002039	active site
107806002040	HIGH motif; other site
107806002041	dimer interface [polypeptide binding]; other site
107806002042	KMSKS motif; other site
107806002043	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
107806002044	substrate binding site [chemical binding]; other site
107806002045	hexamer interface [polypeptide binding]; other site
107806002046	metal binding site [ion binding]; metal-binding site
107806002047	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
107806002048	active site
107806002049	dimer interface [polypeptide binding]; other site
107806002050	metal binding site [ion binding]; metal-binding site
107806002051	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
107806002052	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
107806002053	ADP binding site [chemical binding]; other site
107806002054	magnesium binding site [ion binding]; other site
107806002055	putative shikimate binding site; other site
107806002056	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
107806002057	phosphopentomutase; Provisional; Region: PRK05362
107806002058	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
107806002059	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
107806002060	G1 box; other site
107806002061	putative GEF interaction site [polypeptide binding]; other site
107806002062	GTP/Mg2+ binding site [chemical binding]; other site
107806002063	Switch I region; other site
107806002064	G2 box; other site
107806002065	G3 box; other site
107806002066	Switch II region; other site
107806002067	G4 box; other site
107806002068	G5 box; other site
107806002069	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
107806002070	Elongation Factor G, domain II; Region: EFG_II; pfam14492
107806002071	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
107806002072	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
107806002073	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
107806002074	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
107806002075	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
107806002076	dimer interface [polypeptide binding]; other site
107806002077	ssDNA binding site [nucleotide binding]; other site
107806002078	tetramer (dimer of dimers) interface [polypeptide binding]; other site
107806002079	replicative DNA helicase; Provisional; Region: PRK08006
107806002080	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
107806002081	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
107806002082	Walker A motif; other site
107806002083	ATP binding site [chemical binding]; other site
107806002084	Walker B motif; other site
107806002085	DNA binding loops [nucleotide binding]
107806002086	glutathione synthetase; Provisional; Region: PRK05246
107806002087	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
107806002088	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
107806002089	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
107806002090	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
107806002091	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
107806002092	catalytic residue [active]
107806002093	HemN family oxidoreductase; Provisional; Region: PRK05660
107806002094	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
107806002095	FeS/SAM binding site; other site
107806002096	HemN C-terminal domain; Region: HemN_C; pfam06969
107806002097	Predicted S-adenosylmethionine-dependent methyltransferase [General function prediction only]; Region: COG0220
107806002098	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
107806002099	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
107806002100	minor groove reading motif; other site
107806002101	helix-hairpin-helix signature motif; other site
107806002102	substrate binding pocket [chemical binding]; other site
107806002103	active site
107806002104	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
107806002105	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
107806002106	DNA binding and oxoG recognition site [nucleotide binding]
107806002107	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2924
107806002108	Glutamate racemase [Cell envelope biogenesis, outer membrane]; Region: MurI; COG0796
107806002109	Exonuclease I [DNA replication, recombination, and repair]; Region: SbcB; COG2925
107806002110	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
107806002111	active site
107806002112	catalytic site [active]
107806002113	substrate binding site [chemical binding]; other site
107806002114	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
107806002115	hypothetical protein; Provisional; Region: PRK05423
107806002116	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
107806002117	active site
107806002118	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
107806002119	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
107806002120	trimer interface [polypeptide binding]; other site
107806002121	active site
107806002122	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
107806002123	active site
107806002124	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
107806002125	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
107806002126	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
107806002127	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
107806002128	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
107806002129	ribonuclease R; Region: RNase_R; TIGR02063
107806002130	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
107806002131	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
107806002132	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
107806002133	RNA binding site [nucleotide binding]; other site
107806002134	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
107806002135	GDP-binding site [chemical binding]; other site
107806002136	ACT binding site; other site
107806002137	IMP binding site; other site
107806002138	HflC protein; Region: hflC; TIGR01932
107806002139	High frequency of lysogenization C (HflC) family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_HflC; cd03405
107806002140	FtsH protease regulator HflK; Provisional; Region: PRK10930
107806002141	High frequency of lysogenization K (HflK) family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_HflK; cd03404
107806002142	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
107806002143	DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair]; Region: MutL; COG0323
107806002144	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
107806002145	ATP binding site [chemical binding]; other site
107806002146	Mg2+ binding site [ion binding]; other site
107806002147	G-X-G motif; other site
107806002148	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
107806002149	ATP binding site [chemical binding]; other site
107806002150	MutL C terminal dimerisation domain; Region: MutL_C; smart00853
107806002151	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
107806002152	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
107806002153	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
107806002154	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
107806002155	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
107806002156	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
107806002157	active site
107806002158	P-loop; other site
107806002159	phosphorylation site [posttranslational modification]
107806002160	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
107806002161	active site
107806002162	phosphorylation site [posttranslational modification]
107806002163	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
107806002164	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
107806002165	active site
107806002166	dimer interface [polypeptide binding]; other site
107806002167	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
107806002168	dimer interface [polypeptide binding]; other site
107806002169	active site
107806002170	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
107806002171	catalytic site [active]
107806002172	putative active site [active]
107806002173	putative substrate binding site [chemical binding]; other site
107806002174	dimer interface [polypeptide binding]; other site
107806002175	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
107806002176	active site
107806002177	metal binding site [ion binding]; metal-binding site
107806002178	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
107806002179	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
107806002180	active site
107806002181	HslU subunit interaction site [polypeptide binding]; other site
107806002182	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
107806002183	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
107806002184	Walker A motif; other site
107806002185	ATP binding site [chemical binding]; other site
107806002186	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
107806002187	Walker B motif; other site
107806002188	arginine finger; other site
107806002189	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
107806002190	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
107806002191	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
107806002192	putative dimer interface [polypeptide binding]; other site
107806002193	ferredoxin-NADP reductase; Provisional; Region: PRK10926
107806002194	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
107806002195	FAD binding pocket [chemical binding]; other site
107806002196	FAD binding motif [chemical binding]; other site
107806002197	phosphate binding motif [ion binding]; other site
107806002198	beta-alpha-beta structure motif; other site
107806002199	NAD binding pocket [chemical binding]; other site
107806002200	Truncated, possibly inactive, lysyl-tRNA synthetase (class II) [Translation, ribosomal structure and biogenesis]; Region: COG2269
107806002201	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
107806002202	motif 1; other site
107806002203	dimer interface [polypeptide binding]; other site
107806002204	active site
107806002205	motif 2; other site
107806002206	motif 3; other site
107806002207	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
107806002208	active site
107806002209	(T/H)XGH motif; other site
107806002210	Putative SAM-dependent methyltransferase; Region: SAM_MT; pfam04445
107806002211	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
107806002212	S-adenosylmethionine binding site [chemical binding]; other site
107806002213	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
107806002214	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
107806002215	Major Facilitator Superfamily; Region: MFS_1; pfam07690
107806002216	putative substrate translocation pore; other site
107806002217	Diaminopimelate epimerase [Amino acid transport and metabolism]; Region: DapF; COG0253
107806002218	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
107806002219	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
107806002220	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
107806002221	putative iron binding site [ion binding]; other site
107806002222	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
107806002223	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
107806002224	domain interfaces; other site
107806002225	active site
107806002226	contains authentic frameshift; putative uroporphyrinogen III synthase similar to protein HEM4_ECOLI SW:P09126
107806002227	transcription termination factor Rho; Provisional; Region: rho; PRK09376
107806002228	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
107806002229	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
107806002230	RNA binding site [nucleotide binding]; other site
107806002231	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
107806002232	multimer interface [polypeptide binding]; other site
107806002233	Walker A motif; other site
107806002234	ATP binding site [chemical binding]; other site
107806002235	Walker B motif; other site
107806002236	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
107806002237	catalytic residues [active]
107806002238	ATP-dependent DNA helicase Rep; Region: rep; TIGR01074
107806002239	Part of AAA domain; Region: AAA_19; pfam13245
107806002240	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
107806002241	ketol-acid reductoisomerase; Validated; Region: PRK05225
107806002242	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
107806002243	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
107806002244	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
107806002245	cysteine desulfurase; Provisional; Region: PRK14012
107806002246	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
107806002247	catalytic residue [active]
107806002248	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
107806002249	trimerization site [polypeptide binding]; other site
107806002250	active site
107806002251	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
107806002252	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
107806002253	HSP70 interaction site [polypeptide binding]; other site
107806002254	HSCB C-terminal oligomerization domain; Region: HSCB_C; pfam07743
107806002255	Fe-S protein assembly chaperone HscA; Region: HscA; TIGR01991
107806002256	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
107806002257	nucleotide binding site [chemical binding]; other site
107806002258	putative NEF/HSP70 interaction site [polypeptide binding]; other site
107806002259	SBD interface [polypeptide binding]; other site
107806002260	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
107806002261	catalytic loop [active]
107806002262	iron binding site [ion binding]; other site
107806002263	ribosome-associated GTPase EngA; Region: GTPase_EngA; TIGR03594
107806002264	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
107806002265	G1 box; other site
107806002266	GTP/Mg2+ binding site [chemical binding]; other site
107806002267	Switch I region; other site
107806002268	G2 box; other site
107806002269	Switch II region; other site
107806002270	G3 box; other site
107806002271	G4 box; other site
107806002272	G5 box; other site
107806002273	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
107806002274	G1 box; other site
107806002275	GTP/Mg2+ binding site [chemical binding]; other site
107806002276	Switch I region; other site
107806002277	G2 box; other site
107806002278	G3 box; other site
107806002279	Switch II region; other site
107806002280	G4 box; other site
107806002281	G5 box; other site
107806002282	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal; Region: KH_dom-like; pfam14714
107806002283	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976