-- dump date 20140619_011655 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_005108025.1 376277992 11685836 155..1348 1 NC_016775.1 identified by match to PFAM protein family HMM PF03428; replication initiation protein RepC 1348 repC 11685836 repC Brucella suis VBI22 replication initiation protein RepC YP_005108025.1 155 D 1112912 CDS YP_005108026.1 376277993 11685959 complement(1413..1562) 1 NC_016775.1 hypothetical protein 1562 11685959 BSVBI22_B0002 Brucella suis VBI22 hypothetical protein YP_005108026.1 1413 R 1112912 CDS YP_005108027.1 376277994 11685996 1551..1814 1 NC_016775.1 hypothetical protein 1814 11685996 BSVBI22_B0003 Brucella suis VBI22 hypothetical protein YP_005108027.1 1551 D 1112912 CDS YP_005108028.1 376277995 11686017 1963..2076 1 NC_016775.1 hypothetical protein 2076 11686017 BSVBI22_B0004 Brucella suis VBI22 hypothetical protein YP_005108028.1 1963 D 1112912 CDS YP_005108029.1 376277996 11686064 2092..3033 1 NC_016775.1 similar to GB:M77016, SP:P28289, PID:339948, GB:M77016, SP:P28289, and PID:339948; identified by sequence similarity; putative; ribokinase, putative 3033 11686064 BSVBI22_B0005 Brucella suis VBI22 ribokinase, putative YP_005108029.1 2092 D 1112912 CDS YP_005108030.1 376277997 11686066 complement(3110..4108) 1 NC_016775.1 identified by match to PFAM protein family HMM PF01156; inosine-uridine preferring nucleoside hydrolase 4108 iunH 11686066 iunH Brucella suis VBI22 inosine-uridine preferring nucleoside hydrolase YP_005108030.1 3110 R 1112912 CDS YP_005108031.1 376277998 11686068 complement(4131..5042) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00023; ABC transporter permease 5042 11686068 BSVBI22_B0007 Brucella suis VBI22 ABC transporter permease YP_005108031.1 4131 R 1112912 CDS YP_005108032.1 376277999 11686070 complement(5039..6118) 1 NC_016775.1 similar to GP:13022200, and GP:17134506; identified by sequence similarity; putative; ABC transporter permease 6118 11686070 BSVBI22_B0008 Brucella suis VBI22 ABC transporter permease YP_005108032.1 5039 R 1112912 CDS YP_005108033.1 376278000 11686072 complement(6180..7751) 1 NC_016775.1 similar to GP:13162075, GB:X52974, SP:P40598, and PID:48736; identified by sequence similarity; putative; ABC transporter ATP-binding protein 7751 11686072 BSVBI22_B0009 Brucella suis VBI22 ABC transporter ATP-binding protein YP_005108033.1 6180 R 1112912 CDS YP_005108034.1 376278001 11686152 complement(7754..8860) 1 NC_016775.1 similar to GP:11065692; identified by sequence similarity; putative; Bmp family lipoprotein 8860 11686152 BSVBI22_B0010 Brucella suis VBI22 Bmp family lipoprotein YP_005108034.1 7754 R 1112912 CDS YP_005108035.1 376278002 11686153 9104..9712 1 NC_016775.1 similar to GP:15141208, and GP:15141208; identified by sequence similarity; putative; hypothetical protein 9712 11686153 BSVBI22_B0011 Brucella suis VBI22 hypothetical protein YP_005108035.1 9104 D 1112912 CDS YP_005108036.1 376278003 11686154 complement(9684..10316) 1 NC_016775.1 similar to GP:15158815, and GP:6018425; identified by sequence similarity; putative; enterobactin synthetase subunit D 10316 11686154 BSVBI22_B0012 Brucella suis VBI22 enterobactin synthetase subunit D YP_005108036.1 9684 R 1112912 CDS YP_005108037.1 376278004 11686155 complement(10399..11175) 1 NC_016775.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 11175 entA 11686155 entA Brucella suis VBI22 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_005108037.1 10399 R 1112912 CDS YP_005108038.1 376278005 11686156 complement(11175..12047) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00550; isochorismatase 12047 entB 11686156 entB Brucella suis VBI22 isochorismatase YP_005108038.1 11175 R 1112912 CDS YP_005108039.1 376278006 11686157 complement(12099..13718) 1 NC_016775.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 13718 entE 11686157 entE Brucella suis VBI22 enterobactin synthase subunit E YP_005108039.1 12099 R 1112912 CDS YP_005108040.1 376278007 11686158 complement(13825..15000) 1 NC_016775.1 synthesizes isochorismate acid from chorismate; isochorismate synthase 15000 entC 11686158 entC Brucella suis VBI22 isochorismate synthase YP_005108040.1 13825 R 1112912 CDS YP_005108041.1 376278008 11686159 15072..16481 1 NC_016775.1 similar to GP:13959028, and GP:1778502; identified by sequence similarity; putative; enterobactin synthetase, component F, putative 16481 11686159 BSVBI22_B0017 Brucella suis VBI22 enterobactin synthetase, component F, putative YP_005108041.1 15072 D 1112912 CDS YP_005108042.1 376278009 11686160 complement(16529..17317) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00174; oxidoreductase, molybdopterin-binding protein 17317 11686160 BSVBI22_B0018 Brucella suis VBI22 oxidoreductase, molybdopterin-binding protein YP_005108042.1 16529 R 1112912 CDS YP_005108043.1 376278010 11686161 complement(17314..18123) 1 NC_016775.1 identified by match to PFAM protein family HMM PF01292; HupC/HyaC/HydC family protein 18123 11686161 BSVBI22_B0019 Brucella suis VBI22 HupC/HyaC/HydC family protein YP_005108043.1 17314 R 1112912 CDS YP_005108044.1 376278011 11686162 complement(18184..18405) 1 NC_016775.1 hypothetical protein 18405 11686162 BSVBI22_B0020 Brucella suis VBI22 hypothetical protein YP_005108044.1 18184 R 1112912 CDS YP_005108045.1 376278012 11686163 18590..19114 1 NC_016775.1 similar to GP:15157424; identified by sequence similarity; putative; ECF subfamily RNA polymerase sigma factor 19114 11686163 BSVBI22_B0021 Brucella suis VBI22 ECF subfamily RNA polymerase sigma factor YP_005108045.1 18590 D 1112912 CDS YP_005108046.1 376278013 11686164 19104..19739 1 NC_016775.1 similar to GP:15157423, and GP:15157423; identified by sequence similarity; putative; hypothetical protein 19739 11686164 BSVBI22_B0022 Brucella suis VBI22 hypothetical protein YP_005108046.1 19104 D 1112912 CDS YP_005108047.1 376278014 11686165 complement(19785..20525) 1 NC_016775.1 similar to GP:14523197; identified by sequence similarity; putative; GntR family transcriptional regulator 20525 11686165 BSVBI22_B0023 Brucella suis VBI22 GntR family transcriptional regulator YP_005108047.1 19785 R 1112912 CDS YP_005108048.1 376278015 11686166 20643..22058 1 NC_016775.1 similar to GB:Z11566, GB:J04991, GB:X53305, GB:M31303, GB:D28428, GB:X94912, SP:P16949, PID:1246757, PID:189388, PID:189426, PID:35595, and PID:57870; identified by sequence similarity; putative; branched chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative 22058 11686166 BSVBI22_B0024 Brucella suis VBI22 branched chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative YP_005108048.1 20643 D 1112912 CDS YP_005108049.1 376278016 11686167 22100..23089 1 NC_016775.1 similar to GP:15076000; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, permease protein 23089 11686167 BSVBI22_B0025 Brucella suis VBI22 branched-chain amino acid ABC transporter, permease protein YP_005108049.1 22100 D 1112912 CDS YP_005108050.1 376278017 11686168 23093..24313 1 NC_016775.1 similar to GB:M93015, SP:P29916, and PID:150623; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, permease protein 24313 11686168 BSVBI22_B0026 Brucella suis VBI22 branched-chain amino acid ABC transporter, permease protein YP_005108050.1 23093 D 1112912 CDS YP_005108051.1 376278018 11686169 24313..25065 1 NC_016775.1 similar to GP:15159144; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, ATP-binding protein 25065 11686169 BSVBI22_B0027 Brucella suis VBI22 branched-chain amino acid ABC transporter, ATP-binding protein YP_005108051.1 24313 D 1112912 CDS YP_005108052.1 376278019 11686170 25065..25781 1 NC_016775.1 similar to GB:M93015, SP:P29916, and PID:150623; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, ATP-binding protein 25781 11686170 BSVBI22_B0028 Brucella suis VBI22 branched-chain amino acid ABC transporter, ATP-binding protein YP_005108052.1 25065 D 1112912 CDS YP_005108053.1 376278020 11686171 25833..26315 1 NC_016775.1 identified by match to PFAM protein family HMM PF00903; glyoxalase family protein 26315 11686171 BSVBI22_B0029 Brucella suis VBI22 glyoxalase family protein YP_005108053.1 25833 D 1112912 CDS YP_005108054.1 376278021 11686172 26319..27056 1 NC_016775.1 similar to GB:L13289, SP:P47721, PID:551904, GB:M11147, GB:M10119, GB:M12938, GB:X03742, GB:X03743, SP:P02792, PID:1340145, PID:1340146, PID:182514, PID:182516, PID:182518, PID:2230869, and PID:28519; identified by sequence similarity; putative; 3-oxoacyl-(acyl-carrier-protein) reductase, putative 27056 11686172 BSVBI22_B0030 Brucella suis VBI22 3-oxoacyl-(acyl-carrier-protein) reductase, putative YP_005108054.1 26319 D 1112912 CDS YP_005108055.1 376278022 11686173 27074..27826 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01500; short chain dehydrogenase/reductase family oxidoreductase 27826 11686173 BSVBI22_B0031 Brucella suis VBI22 short chain dehydrogenase/reductase family oxidoreductase YP_005108055.1 27074 D 1112912 CDS YP_005108056.1 376278023 11686174 27936..30125 1 NC_016775.1 similar to SP:P27746, GB:X52592, and PID:46994; identified by sequence similarity; putative; acetoin dehydrogenase, alpha/beta subunit, putative 30125 11686174 BSVBI22_B0032 Brucella suis VBI22 acetoin dehydrogenase, alpha/beta subunit, putative YP_005108056.1 27936 D 1112912 CDS YP_005108057.1 376278024 11686175 30144..31409 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01348; branched-chain alpha-keto acid dehydrogenase subunit E2 31409 11686175 BSVBI22_B0033 Brucella suis VBI22 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_005108057.1 30144 D 1112912 CDS YP_005108058.1 376278025 11686176 31510..32295 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00507; shikimate dehydrogenase family protein 32295 11686176 BSVBI22_B0034 Brucella suis VBI22 shikimate dehydrogenase family protein YP_005108058.1 31510 D 1112912 CDS YP_005108059.1 376278026 11686177 32575..32868 1 NC_016775.1 hypothetical protein 32868 11686177 BSVBI22_B0035 Brucella suis VBI22 hypothetical protein YP_005108059.1 32575 D 1112912 CDS YP_005108060.1 376278027 11686178 complement(32822..33103) 1 NC_016775.1 hypothetical protein 33103 11686178 BSVBI22_B0036 Brucella suis VBI22 hypothetical protein YP_005108060.1 32822 R 1112912 CDS YP_005108061.1 376278028 11686179 33221..35938 1 NC_016775.1 similar to GP:397973; identified by sequence similarity; putative; magnesium ion-transporting ATPase E1-E2 family protein 35938 11686179 BSVBI22_B0037 Brucella suis VBI22 magnesium ion-transporting ATPase E1-E2 family protein YP_005108061.1 33221 D 1112912 CDS YP_005108062.1 376278029 11686180 36023..36373 1 NC_016775.1 hypothetical protein 36373 11686180 BSVBI22_B0038 Brucella suis VBI22 hypothetical protein YP_005108062.1 36023 D 1112912 CDS YP_005108063.1 376278030 11686181 36504..36707 1 NC_016775.1 hypothetical protein 36707 11686181 BSVBI22_B0039 Brucella suis VBI22 hypothetical protein YP_005108063.1 36504 D 1112912 CDS YP_005108064.1 376278031 11686182 36709..37425 1 NC_016775.1 similar to GB:L33799, and PID:642908; identified by sequence similarity; putative; MgtC family protein 37425 11686182 BSVBI22_B0040 Brucella suis VBI22 MgtC family protein YP_005108064.1 36709 D 1112912 CDS YP_005108065.1 376278032 11686183 37500..38570 1 NC_016775.1 similar to GB:M57423, SP:P09329, SP:P11908, SP:P21108, PID:190522, and PID:2160401; identified by sequence similarity; putative; sensor histidine kinase 38570 11686183 BSVBI22_B0041 Brucella suis VBI22 sensor histidine kinase YP_005108065.1 37500 D 1112912 CDS YP_005108066.1 376278033 11686184 38567..39205 1 NC_016775.1 similar to GB:L22075, SP:Q14344, and PID:404722; identified by sequence similarity; putative; LuxR family DNA-binding response regulator 39205 11686184 BSVBI22_B0042 Brucella suis VBI22 LuxR family DNA-binding response regulator YP_005108066.1 38567 D 1112912 CDS YP_005108067.1 376278034 11686186 complement(39591..39953) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00072; response regulator 39953 11686186 BSVBI22_B0043 Brucella suis VBI22 response regulator YP_005108067.1 39591 R 1112912 CDS YP_005108068.1 376278035 11686187 40272..41162 1 NC_016775.1 formiminoglutamase, putative 41162 11686187 BSVBI22_B0044 Brucella suis VBI22 formiminoglutamase, putative YP_005108068.1 40272 D 1112912 CDS YP_005108069.1 376278036 11686188 41324..42100 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01330; inositol monophosphatase family protein 42100 11686188 BSVBI22_B0045 Brucella suis VBI22 inositol monophosphatase family protein YP_005108069.1 41324 D 1112912 CDS YP_005108070.1 376278037 11686189 complement(42151..43146) 1 NC_016775.1 similar to GB:X15949, SP:P14316, and PID:33967; identified by sequence similarity; putative; lysophospholipase L2, putative 43146 11686189 BSVBI22_B0046 Brucella suis VBI22 lysophospholipase L2, putative YP_005108070.1 42151 R 1112912 CDS YP_005108071.1 376278038 11686190 complement(43186..43401) 1 NC_016775.1 hypothetical protein 43401 11686190 BSVBI22_B0047 Brucella suis VBI22 hypothetical protein YP_005108071.1 43186 R 1112912 CDS YP_005108072.1 376278039 11686191 complement(43496..43894) 1 NC_016775.1 hypothetical protein 43894 11686191 BSVBI22_B0048 Brucella suis VBI22 hypothetical protein YP_005108072.1 43496 R 1112912 CDS YP_005108073.1 376278040 11686192 43946..44155 1 NC_016775.1 hypothetical protein 44155 11686192 BSVBI22_B0049 Brucella suis VBI22 hypothetical protein YP_005108073.1 43946 D 1112912 CDS YP_005108074.1 376278041 11686193 44128..44379 1 NC_016775.1 hypothetical protein 44379 11686193 BSVBI22_B0050 Brucella suis VBI22 hypothetical protein YP_005108074.1 44128 D 1112912 CDS YP_005108075.1 376278042 11686194 44458..44928 1 NC_016775.1 similar to GB:X01703, GB:K00557, SP:P04687, SP:P05215, PID:340019, PID:340021, and PID:37492; identified by sequence similarity; putative; 16 kDa heat shock protein A 44928 ibpA 11686194 ibpA Brucella suis VBI22 16 kDa heat shock protein A YP_005108075.1 44458 D 1112912 CDS YP_005108076.1 376278043 11686195 complement(45066..46115) 1 NC_016775.1 threonine aldolase, low-specificity, putative 46115 11686195 BSVBI22_B0052 Brucella suis VBI22 threonine aldolase, low-specificity, putative YP_005108076.1 45066 R 1112912 CDS YP_005108077.1 376278044 11686196 complement(46384..46668) 1 NC_016775.1 hypothetical protein 46668 11686196 BSVBI22_B0053 Brucella suis VBI22 hypothetical protein YP_005108077.1 46384 R 1112912 CDS YP_005108078.1 376278045 11686197 46758..51509 1 NC_016775.1 similar to SP:P04993, GB:X04581, GB:X04582, PID:42683, PID:42691, PID:882711, GB:U00096, and PID:1789182; identified by sequence similarity; putative; glutamate synthase, large subunit 51509 gltB 11686197 gltB Brucella suis VBI22 glutamate synthase, large subunit YP_005108078.1 46758 D 1112912 CDS YP_005108079.1 376278046 11686198 51591..53045 1 NC_016775.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 53045 gltD 11686198 gltD Brucella suis VBI22 glutamate synthase subunit beta YP_005108079.1 51591 D 1112912 CDS YP_005108080.1 376278047 11686199 complement(53090..54493) 1 NC_016775.1 similar to SP:O06005, GB:M86808, SP:P29803, and PID:190790; identified by sequence similarity; putative; amino acid permease family protein 54493 11686199 BSVBI22_B0056 Brucella suis VBI22 amino acid permease family protein YP_005108080.1 53090 R 1112912 CDS YP_005108081.1 376278048 11686200 complement(54715..55866) 1 NC_016775.1 similar to GP:15075833; identified by sequence similarity; putative; hypothetical protein 55866 11686200 BSVBI22_B0057 Brucella suis VBI22 hypothetical protein YP_005108081.1 54715 R 1112912 CDS YP_005108082.1 376278049 11686201 complement(56117..56635) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00691; putative lipoprotein 56635 11686201 BSVBI22_B0058 Brucella suis VBI22 putative lipoprotein YP_005108082.1 56117 R 1112912 CDS YP_005108083.1 376278050 11686202 complement(56784..57869) 1 NC_016775.1 similar to GP:5929876, and GP:8163894; identified by sequence similarity; putative; type IV secretion system protein VirB11 57869 11686202 BSVBI22_B0059 Brucella suis VBI22 type IV secretion system protein VirB11 YP_005108083.1 56784 R 1112912 CDS YP_005108084.1 376278051 11686203 complement(57850..59025) 1 NC_016775.1 similar to GP:5929875, and GP:5929875; identified by sequence similarity; putative; type IV secretion system protein VirB10 59025 11686203 BSVBI22_B0060 Brucella suis VBI22 type IV secretion system protein VirB10 YP_005108084.1 57850 R 1112912 CDS YP_005108085.1 376278052 11686204 complement(59022..59891) 1 NC_016775.1 similar to GP:5929874, and GP:5929874; identified by sequence similarity; putative; type IV secretion system protein VirB9 59891 11686204 BSVBI22_B0061 Brucella suis VBI22 type IV secretion system protein VirB9 YP_005108085.1 59022 R 1112912 CDS YP_005108086.1 376278053 11686205 complement(59888..60607) 1 NC_016775.1 similar to GP:5929873, and GP:5929873; identified by sequence similarity; putative; type IV secretion system protein VirB8 60607 11686205 BSVBI22_B0062 Brucella suis VBI22 type IV secretion system protein VirB8 YP_005108086.1 59888 R 1112912 CDS YP_005108087.1 376278054 11686206 complement(60610..60783) 1 NC_016775.1 similar to GP:5929872; identified by sequence similarity; putative; type IV secretion system protein VirB7 60783 11686206 BSVBI22_B0063 Brucella suis VBI22 type IV secretion system protein VirB7 YP_005108087.1 60610 R 1112912 CDS YP_005108088.1 376278055 11686207 complement(60947..61990) 1 NC_016775.1 similar to GP:8163889, and GP:8163889; identified by sequence similarity; putative; type IV secretion system protein VirB6 61990 11686207 BSVBI22_B0064 Brucella suis VBI22 type IV secretion system protein VirB6 YP_005108088.1 60947 R 1112912 CDS YP_005108089.1 376278056 11686208 complement(62174..62890) 1 NC_016775.1 similar to GP:5929870, and GP:5929870; identified by sequence similarity; putative; type IV secretion system protein VirB5 62890 11686208 BSVBI22_B0065 Brucella suis VBI22 type IV secretion system protein VirB5 YP_005108089.1 62174 R 1112912 CDS YP_005108090.1 376278057 11686209 complement(62895..65390) 1 NC_016775.1 similar to GP:8163887, and GP:8163887; identified by sequence similarity; putative; type IV secretion system protein VirB4 65390 11686209 BSVBI22_B0066 Brucella suis VBI22 type IV secretion system protein VirB4 YP_005108090.1 62895 R 1112912 CDS YP_005108091.1 376278058 11686210 complement(65390..65740) 1 NC_016775.1 similar to GP:5929868, and GP:5929868; identified by sequence similarity; putative; type IV secretion system protein VirB3 65740 11686210 BSVBI22_B0067 Brucella suis VBI22 type IV secretion system protein VirB3 YP_005108091.1 65390 R 1112912 CDS YP_005108092.1 376278059 11686211 complement(65754..66071) 1 NC_016775.1 similar to GP:5929867, and GP:5929867; identified by sequence similarity; putative; type IV secretion system protein VirB2 66071 11686211 BSVBI22_B0068 Brucella suis VBI22 type IV secretion system protein VirB2 YP_005108092.1 65754 R 1112912 CDS YP_005108093.1 376278060 11686212 complement(66507..67223) 1 NC_016775.1 similar to GP:5929866, and GP:5929866; identified by sequence similarity; putative; type IV secretion system protein VirB1 67223 11686212 BSVBI22_B0069 Brucella suis VBI22 type IV secretion system protein VirB1 YP_005108093.1 66507 R 1112912 CDS YP_005108094.1 376278061 11686213 complement(67727..68953) 1 NC_016775.1 identified by match to PFAM protein family HMM PF01471; transglycosylase, putative 68953 11686213 BSVBI22_B0070 Brucella suis VBI22 transglycosylase, putative YP_005108094.1 67727 R 1112912 CDS YP_005108095.1 376278062 11686214 69365..70258 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01208; UTP--glucose-1-phosphate uridylyltransferase 70258 galU 11686214 galU Brucella suis VBI22 UTP--glucose-1-phosphate uridylyltransferase YP_005108095.1 69365 D 1112912 CDS YP_005108096.1 376278063 11686215 complement(70311..71849) 1 NC_016775.1 similar to GP:14023404; identified by sequence similarity; putative; hypothetical protein 71849 11686215 BSVBI22_B0072 Brucella suis VBI22 hypothetical protein YP_005108096.1 70311 R 1112912 CDS YP_005108097.1 376278064 11686216 71990..72991 1 NC_016775.1 similar to GP:15159530; identified by sequence similarity; putative; sugar isomerase, KpsF/GutQ 72991 11686216 BSVBI22_B0073 Brucella suis VBI22 sugar isomerase, KpsF/GutQ YP_005108097.1 71990 D 1112912 CDS YP_005108098.1 376278065 11686217 complement(73122..73589) 1 NC_016775.1 hypothetical protein 73589 11686217 BSVBI22_B0074 Brucella suis VBI22 hypothetical protein YP_005108098.1 73122 R 1112912 CDS YP_005108099.1 376278066 11686218 complement(73610..74596) 1 NC_016775.1 similar to GP:15159532; identified by sequence similarity; putative; SPFH domain-containing protein/band 7 family protein 74596 11686218 BSVBI22_B0075 Brucella suis VBI22 SPFH domain-containing protein/band 7 family protein YP_005108099.1 73610 R 1112912 CDS YP_005108100.1 376278067 11686219 complement(74729..75787) 1 NC_016775.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 75787 hemH 11686219 hemH Brucella suis VBI22 ferrochelatase YP_005108100.1 74729 R 1112912 CDS YP_005108101.1 376278068 11686220 complement(75925..76305) 1 NC_016775.1 similar to GP:13877130, and GP:13877130; identified by sequence similarity; putative; lipoprotein Omp10 76305 omp10 11686220 omp10 Brucella suis VBI22 lipoprotein Omp10 YP_005108101.1 75925 R 1112912 CDS YP_005108102.1 376278069 11686221 complement(76447..77892) 1 NC_016775.1 similar to GP:2276407; identified by sequence similarity; putative; homospermidine synthase 77892 11686221 BSVBI22_B0078 Brucella suis VBI22 homospermidine synthase YP_005108102.1 76447 R 1112912 CDS YP_005108103.1 376278070 11686222 complement(78004..78684) 1 NC_016775.1 similar to GP:14023390, and GP:14023390; identified by sequence similarity; putative; hypothetical protein 78684 11686222 BSVBI22_B0079 Brucella suis VBI22 hypothetical protein YP_005108103.1 78004 R 1112912 CDS YP_005108104.1 376278071 11686223 complement(78618..79787) 1 NC_016775.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; aminodeoxychorismate synthase 79787 11686223 BSVBI22_B0080 Brucella suis VBI22 aminodeoxychorismate synthase YP_005108104.1 78618 R 1112912 CDS YP_005108105.1 376278072 11686224 complement(79797..81659) 1 NC_016775.1 identified by match to PFAM protein family HMM PF01432; oligoendopeptidase F 81659 pepF 11686224 pepF Brucella suis VBI22 oligoendopeptidase F YP_005108105.1 79797 R 1112912 CDS YP_005108106.1 376278073 11686225 82007..83497 1 NC_016775.1 similar to GP:15159542; identified by sequence similarity; putative; sigma-54 dependent DNA-binding response regulator 83497 11686225 BSVBI22_B0082 Brucella suis VBI22 sigma-54 dependent DNA-binding response regulator YP_005108106.1 82007 D 1112912 CDS YP_005108107.1 376278074 11686226 83838..85751 1 NC_016775.1 similar to GP:14023385; identified by sequence similarity; putative; hypothetical protein 85751 11686226 BSVBI22_B0083 Brucella suis VBI22 hypothetical protein YP_005108107.1 83838 D 1112912 CDS YP_005108108.1 376278075 11686229 87345..88271 1 NC_016775.1 identified by match to PFAM protein family HMM PF00581; rhodanese family protein 88271 11686229 BSVBI22_B0086 Brucella suis VBI22 rhodanese family protein YP_005108108.1 87345 D 1112912 CDS YP_005108109.1 376278076 11686230 88306..88512 1 NC_016775.1 hypothetical protein 88512 11686230 BSVBI22_B0087 Brucella suis VBI22 hypothetical protein YP_005108109.1 88306 D 1112912 CDS YP_005108110.1 376278077 11686231 88552..89307 1 NC_016775.1 similar to GP:15157753; identified by sequence similarity; putative; molybdenum ABC transporter, periplasmic molybdenum-binding protein 89307 modA 11686231 modA Brucella suis VBI22 molybdenum ABC transporter, periplasmic molybdenum-binding protein YP_005108110.1 88552 D 1112912 CDS YP_005108111.1 376278078 11686232 89318..90004 1 NC_016775.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease protein 90004 modB 11686232 modB Brucella suis VBI22 molybdate ABC transporter permease protein YP_005108111.1 89318 D 1112912 CDS YP_005108112.1 376278079 11686233 90001..91080 1 NC_016775.1 similar to SP:P09833; identified by sequence similarity; putative; molybdenum ABC transporter, ATP-binding protein 91080 modC 11686233 modC Brucella suis VBI22 molybdenum ABC transporter, ATP-binding protein YP_005108112.1 90001 D 1112912 CDS YP_005108113.1 376278080 11686234 91150..91827 1 NC_016775.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 91827 11686234 BSVBI22_B0091 Brucella suis VBI22 acetyltransferase YP_005108113.1 91150 D 1112912 CDS YP_005108114.1 376278081 11686235 91814..92023 1 NC_016775.1 hypothetical protein 92023 11686235 BSVBI22_B0092 Brucella suis VBI22 hypothetical protein YP_005108114.1 91814 D 1112912 CDS YP_005108115.1 376278082 11686236 complement(92075..92428) 1 NC_016775.1 hypothetical protein 92428 11686236 BSVBI22_B0093 Brucella suis VBI22 hypothetical protein YP_005108115.1 92075 R 1112912 CDS YP_005108116.1 376278083 11686237 complement(92485..92826) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01598; hypothetical protein 92826 11686237 BSVBI22_B0094 Brucella suis VBI22 hypothetical protein YP_005108116.1 92485 R 1112912 CDS YP_005108117.1 376278084 11686238 complement(92968..94071) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03741; hypothetical protein 94071 11686238 BSVBI22_B0095 Brucella suis VBI22 hypothetical protein YP_005108117.1 92968 R 1112912 CDS YP_005108118.1 376278085 11686239 complement(94071..94775) 1 NC_016775.1 similar to GP:15158721; identified by sequence similarity; putative; hypothetical protein 94775 11686239 BSVBI22_B0096 Brucella suis VBI22 hypothetical protein YP_005108118.1 94071 R 1112912 CDS YP_005108119.1 376278086 11686240 complement(94815..95708) 1 NC_016775.1 identified by match to PFAM protein family HMM PF02492; LysR family transcriptional regulator 95708 11686240 BSVBI22_B0097 Brucella suis VBI22 LysR family transcriptional regulator YP_005108119.1 94815 R 1112912 CDS YP_005108120.1 376278087 11686241 complement(95712..96917) 1 NC_016775.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 96917 11686241 BSVBI22_B0098 Brucella suis VBI22 amidase YP_005108120.1 95712 R 1112912 CDS YP_005108121.1 376278088 11686242 97502..98635 1 NC_016775.1 similar to SP:O50657; identified by sequence similarity; putative; ornithine/DAP/arginine decarboxylase family decarboxylase 2 98635 11686242 BSVBI22_B0099 Brucella suis VBI22 ornithine/DAP/arginine decarboxylase family decarboxylase 2 YP_005108121.1 97502 D 1112912 CDS YP_005108122.1 376278089 11686243 complement(98711..100429) 1 NC_016775.1 similar to GP:15141223; identified by sequence similarity; putative; polysaccharide accessory transport protein, putative 100429 11686243 BSVBI22_B0100 Brucella suis VBI22 polysaccharide accessory transport protein, putative YP_005108122.1 98711 R 1112912 CDS YP_005108123.1 376278090 11686244 complement(100446..100583) 1 NC_016775.1 hypothetical protein 100583 11686244 BSVBI22_B0101 Brucella suis VBI22 hypothetical protein YP_005108123.1 100446 R 1112912 CDS YP_005108124.1 376278091 11686245 complement(100555..101457) 1 NC_016775.1 similar to GP:14026189; identified by sequence similarity; putative; hypothetical protein 101457 11686245 BSVBI22_B0102 Brucella suis VBI22 hypothetical protein YP_005108124.1 100555 R 1112912 CDS YP_005108125.1 376278092 11686246 complement(101415..102176) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03808; WecB/TagA/CpsF family glycosyl transferase 102176 11686246 BSVBI22_B0103 Brucella suis VBI22 WecB/TagA/CpsF family glycosyl transferase YP_005108125.1 101415 R 1112912 CDS YP_005108126.1 376278093 11686247 complement(102177..103331) 1 NC_016775.1 hypothetical protein 103331 11686247 BSVBI22_B0104 Brucella suis VBI22 hypothetical protein YP_005108126.1 102177 R 1112912 CDS YP_005108127.1 376278094 11686248 103325..103453 1 NC_016775.1 hypothetical protein 103453 11686248 BSVBI22_B0105 Brucella suis VBI22 hypothetical protein YP_005108127.1 103325 D 1112912 CDS YP_005108128.1 376278095 11686249 103503..104495 1 NC_016775.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase, group 2 family protein 104495 11686249 BSVBI22_B0106 Brucella suis VBI22 glycosyl transferase, group 2 family protein YP_005108128.1 103503 D 1112912 CDS YP_005108129.1 376278096 11686250 104464..105789 1 NC_016775.1 exopolysaccharide production protein, putative 105789 11686250 BSVBI22_B0107 Brucella suis VBI22 exopolysaccharide production protein, putative YP_005108129.1 104464 D 1112912 CDS YP_005108130.1 376278097 11686251 105803..106939 1 NC_016775.1 similar to GP:15076091; identified by sequence similarity; putative; Gfo/Idh/MocA family oxidoreductase 106939 11686251 BSVBI22_B0108 Brucella suis VBI22 Gfo/Idh/MocA family oxidoreductase YP_005108130.1 105803 D 1112912 CDS YP_005108131.1 376278098 11686252 complement(106936..107985) 1 NC_016775.1 similar to GP:6469270; identified by sequence similarity; putative; Gfo/Idh/MocA family oxidoreductase 107985 11686252 BSVBI22_B0109 Brucella suis VBI22 Gfo/Idh/MocA family oxidoreductase YP_005108131.1 106936 R 1112912 CDS YP_005108132.1 376278099 11686253 108302..109711 1 NC_016775.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 109711 gnd 11686253 gnd Brucella suis VBI22 6-phosphogluconate dehydrogenase YP_005108132.1 108302 D 1112912 CDS YP_005108133.1 376278100 11686254 complement(109807..110868) 1 NC_016775.1 similar to GP:15157291; identified by sequence similarity; putative; spermidine/putrescine ABC transporter, ATP-binding protein 110868 11686254 BSVBI22_B0111 Brucella suis VBI22 spermidine/putrescine ABC transporter, ATP-binding protein YP_005108133.1 109807 R 1112912 CDS YP_005108134.1 376278101 11686255 complement(110874..111692) 1 NC_016775.1 similar to GP:15075242, and GP:17740614; identified by sequence similarity; putative; spermidine/putrescine ABC transporter, permease protein, putative 111692 11686255 BSVBI22_B0112 Brucella suis VBI22 spermidine/putrescine ABC transporter, permease protein, putative YP_005108134.1 110874 R 1112912 CDS YP_005108135.1 376278102 11686256 complement(111698..112582) 1 NC_016775.1 similar to GP:15075241, and GP:17740613; identified by sequence similarity; putative; spermidine/putrescine ABC transporter, permease protein, putative 112582 11686256 BSVBI22_B0113 Brucella suis VBI22 spermidine/putrescine ABC transporter, permease protein, putative YP_005108135.1 111698 R 1112912 CDS YP_005108136.1 376278103 11686257 complement(112791..113894) 1 NC_016775.1 similar to GP:15075240; identified by sequence similarity; putative; ABC transporter, periplasmic substrate-binding protein 113894 11686257 BSVBI22_B0114 Brucella suis VBI22 ABC transporter, periplasmic substrate-binding protein YP_005108136.1 112791 R 1112912 CDS YP_005108137.1 376278104 11686258 complement(114303..115892) 1 NC_016775.1 identified by match to PFAM protein family HMM PF04039; Bcr/CflA subfamily drug resistance transporter 115892 11686258 BSVBI22_B0115 Brucella suis VBI22 Bcr/CflA subfamily drug resistance transporter YP_005108137.1 114303 R 1112912 CDS YP_005108138.1 376278105 11686260 117327..118070 1 NC_016775.1 identified by match to PFAM protein family HMM PF00440; TetR family transcriptional regulator 118070 11686260 BSVBI22_B0117 Brucella suis VBI22 TetR family transcriptional regulator YP_005108138.1 117327 D 1112912 CDS YP_005108139.1 376278106 11686261 118344..119123 1 NC_016775.1 similar to GP:9622950; identified by sequence similarity; putative; LuxR family transcriptional regulator 119123 11686261 BSVBI22_B0118 Brucella suis VBI22 LuxR family transcriptional regulator YP_005108139.1 118344 D 1112912 CDS YP_005108140.1 376278107 11686262 complement(119192..119611) 1 NC_016775.1 similar to GP:15073579, and GP:15073579; identified by sequence similarity; putative; hypothetical protein 119611 11686262 BSVBI22_B0119 Brucella suis VBI22 hypothetical protein YP_005108140.1 119192 R 1112912 CDS YP_005108141.1 376278108 11686263 complement(119731..120801) 1 NC_016775.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 120801 flhB 11686263 flhB Brucella suis VBI22 flagellar biosynthesis protein FlhB YP_005108141.1 119731 R 1112912 CDS YP_005108142.1 376278109 11686265 complement(121890..122210) 1 NC_016775.1 identified by match to PFAM protein family HMM PF01052; flagellar motor switch protein FliN, putative 122210 11686265 BSVBI22_B0122 Brucella suis VBI22 flagellar motor switch protein FliN, putative YP_005108142.1 121890 R 1112912 CDS YP_005108143.1 376278110 11686266 complement(122234..122695) 1 NC_016775.1 hypothetical protein 122695 11686266 BSVBI22_B0123 Brucella suis VBI22 hypothetical protein YP_005108143.1 122234 R 1112912 CDS YP_005108144.1 376278111 11686267 complement(122676..123626) 1 NC_016775.1 similar to SP:O54246; identified by sequence similarity; putative; flagellar motor switch protein FliM, putative 123626 11686267 BSVBI22_B0124 Brucella suis VBI22 flagellar motor switch protein FliM, putative YP_005108144.1 122676 R 1112912 CDS YP_005108145.1 376278112 11686268 complement(123628..124500) 1 NC_016775.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 124500 motA 11686268 motA Brucella suis VBI22 flagellar motor protein MotA YP_005108145.1 123628 R 1112912 CDS YP_005108146.1 376278113 11686269 124658..125434 1 NC_016775.1 similar to GP:15155497, and GP:15073585; identified by sequence similarity; putative; hypothetical protein 125434 11686269 BSVBI22_B0126 Brucella suis VBI22 hypothetical protein YP_005108146.1 124658 D 1112912 CDS YP_005108147.1 376278114 11686270 125434..126165 1 NC_016775.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod protein FlgF 126165 flgF 11686270 flgF Brucella suis VBI22 flagellar basal body rod protein FlgF YP_005108147.1 125434 D 1112912 CDS YP_005108148.1 376278115 11686271 126162..127430 1 NC_016775.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 127430 fliI 11686271 fliI Brucella suis VBI22 flagellum-specific ATP synthase YP_005108148.1 126162 D 1112912 CDS YP_005108149.1 376278116 11686272 127514..128032 1 NC_016775.1 similar to GP:2916792, and GP:2459710; identified by sequence similarity; putative; hypothetical protein 128032 11686272 BSVBI22_B0129 Brucella suis VBI22 hypothetical protein YP_005108149.1 127514 D 1112912 CDS YP_005108150.1 376278117 11686273 complement(128057..129034) 1 NC_016775.1 identified by match to PFAM protein family HMM PF01569; PAP2 family protein 129034 11686273 BSVBI22_B0130 Brucella suis VBI22 PAP2 family protein YP_005108150.1 128057 R 1112912 CDS YP_005108151.1 376278118 11686274 129022..129177 1 NC_016775.1 hypothetical protein 129177 11686274 BSVBI22_B0131 Brucella suis VBI22 hypothetical protein YP_005108151.1 129022 D 1112912 CDS YP_005108152.1 376278119 11686275 complement(129332..129550) 1 NC_016775.1 hypothetical protein 129550 11686275 BSVBI22_B0132 Brucella suis VBI22 hypothetical protein YP_005108152.1 129332 R 1112912 CDS YP_005108153.1 376278120 11686276 129578..129973 1 NC_016775.1 identified by match to PFAM protein family HMM PF03751; hypothetical protein 129973 11686276 BSVBI22_B0133 Brucella suis VBI22 hypothetical protein YP_005108153.1 129578 D 1112912 CDS YP_005108154.1 376278121 11686277 129970..130950 1 NC_016775.1 similar to GB:Z17227, SP:Q08334, PID:393379, and PID:571296; identified by sequence similarity; putative; glycosyl transferase, group 2 family protein 130950 11686277 BSVBI22_B0134 Brucella suis VBI22 glycosyl transferase, group 2 family protein YP_005108154.1 129970 D 1112912 CDS YP_005108155.1 376278122 11686278 130934..131683 1 NC_016775.1 identified by match to PFAM protein family HMM PF03633; hypothetical protein 131683 11686278 BSVBI22_B0135 Brucella suis VBI22 hypothetical protein YP_005108155.1 130934 D 1112912 CDS YP_005108156.1 376278123 11686279 131680..133116 1 NC_016775.1 similar to GP:4433524; identified by sequence similarity; putative; dolichyl-phosphate-mannose-protein mannosyltransferase family protein 133116 11686279 BSVBI22_B0136 Brucella suis VBI22 dolichyl-phosphate-mannose-protein mannosyltransferase family protein YP_005108156.1 131680 D 1112912 CDS YP_005108157.1 376278124 11686280 complement(133238..133360) 1 NC_016775.1 hypothetical protein 133360 11686280 BSVBI22_B0137 Brucella suis VBI22 hypothetical protein YP_005108157.1 133238 R 1112912 CDS YP_005108158.1 376278125 11686281 133359..134315 1 NC_016775.1 similar to GP:15159134; identified by sequence similarity; putative; AraC family transcriptional regulator 134315 11686281 BSVBI22_B0138 Brucella suis VBI22 AraC family transcriptional regulator YP_005108158.1 133359 D 1112912 CDS YP_005108159.1 376278126 11686282 134577..134681 1 NC_016775.1 hypothetical protein 134681 11686282 BSVBI22_B0139 Brucella suis VBI22 hypothetical protein YP_005108159.1 134577 D 1112912 CDS YP_005108160.1 376278127 11686283 134671..135108 1 NC_016775.1 identified by match to PFAM protein family HMM PF01527; SyrB family protein, putative 135108 11686283 BSVBI22_B0140 Brucella suis VBI22 SyrB family protein, putative YP_005108160.1 134671 D 1112912 CDS YP_005108161.1 376278128 11686284 135130..135240 1 NC_016775.1 hypothetical protein 135240 11686284 BSVBI22_B0141 Brucella suis VBI22 hypothetical protein YP_005108161.1 135130 D 1112912 CDS YP_005108162.1 376278129 11686285 complement(135302..136603) 1 NC_016775.1 similar to GP:5281442, GB:U12431, SP:P26378, PID:521144, and PID:905387; identified by sequence similarity; putative; phthalate transporter, putative 136603 11686285 BSVBI22_B0142 Brucella suis VBI22 phthalate transporter, putative YP_005108162.1 135302 R 1112912 CDS YP_005108163.1 376278130 11686286 complement(136629..137261) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00760; putative aldolase 137261 11686286 BSVBI22_B0143 Brucella suis VBI22 putative aldolase YP_005108163.1 136629 R 1112912 CDS YP_005108164.1 376278131 11686287 complement(137287..138252) 1 NC_016775.1 similar to GB:M31651, GB:M27542, GB:X16351, GB:X05403, GB:X05792, GB:X16349, GB:X16350, SP:P04278, SP:P14689, PID:1335305, PID:36452, PID:825718, GB:M31651, GB:M27542, GB:X16351, GB:X05403, GB:X05792, GB:X16349, GB:X16350, SP:P04278, SP:P14689, PID:1335305, PID:36452, and PID:825718; identified by sequence similarity; putative; hypothetical protein 138252 11686287 BSVBI22_B0144 Brucella suis VBI22 hypothetical protein YP_005108164.1 137287 R 1112912 CDS YP_005108165.1 376278132 11686288 complement(138252..139043) 1 NC_016775.1 similar to GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, and PID:386807; identified by sequence similarity; putative; DeoR family transcriptional regulator 139043 11686288 BSVBI22_B0145 Brucella suis VBI22 DeoR family transcriptional regulator YP_005108165.1 138252 R 1112912 CDS YP_005108166.1 376278133 11686289 complement(139040..139825) 1 NC_016775.1 similar to GP:10197687, GB:J03799, GB:X15005, GB:S37431, GB:M14199, GB:X61156, GB:U36484, SP:P08865, PID:1125065, PID:34272, and PID:386857; identified by sequence similarity; putative; hydroxypyruvate isomerase, putative 139825 11686289 BSVBI22_B0146 Brucella suis VBI22 hydroxypyruvate isomerase, putative YP_005108166.1 139040 R 1112912 CDS YP_005108167.1 376278134 11686290 complement(139825..141099) 1 NC_016775.1 similar to GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, and PID:386807; identified by sequence similarity; putative; hypothetical protein 141099 11686290 BSVBI22_B0147 Brucella suis VBI22 hypothetical protein YP_005108167.1 139825 R 1112912 CDS YP_005108168.1 376278135 11686291 142158..142295 1 NC_016775.1 hypothetical protein 142295 11686291 BSVBI22_B0148 Brucella suis VBI22 hypothetical protein YP_005108168.1 142158 D 1112912 CDS YP_005108169.1 376278136 11686292 142372..142752 1 NC_016775.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the proteins in this cluster are associated with the thin flagella; flagellar basal body rod protein FlgB 142752 flgB 11686292 flgB Brucella suis VBI22 flagellar basal body rod protein FlgB YP_005108169.1 142372 D 1112912 CDS YP_005108170.1 376278137 11686293 142755..143177 1 NC_016775.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 143177 flgC 11686293 flgC Brucella suis VBI22 flagellar basal body rod protein FlgC YP_005108170.1 142755 D 1112912 CDS YP_005108171.1 376278138 11686294 143177..143512 1 NC_016775.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar hook-basal body protein FliE 143512 fliE 11686294 fliE Brucella suis VBI22 flagellar hook-basal body protein FliE YP_005108171.1 143177 D 1112912 CDS YP_005108172.1 376278139 11686295 143598..144386 1 NC_016775.1 makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella; flagellar basal body rod protein FlgG 144386 flgG 11686295 flgG Brucella suis VBI22 flagellar basal body rod protein FlgG YP_005108172.1 143598 D 1112912 CDS YP_005108173.1 376278140 11686296 144398..144880 1 NC_016775.1 required for the assembly of the flagellar basal body P-ring; Bradyrhizobium japonicum has two types of flagella, a single thick flagella and a few thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body P-ring biosynthesis protein FlgA 144880 flgA 11686296 flgA Brucella suis VBI22 flagellar basal body P-ring biosynthesis protein FlgA YP_005108173.1 144398 D 1112912 CDS YP_005108174.1 376278141 11686297 145177..146250 1 NC_016775.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 146250 flgI 11686297 flgI Brucella suis VBI22 flagellar basal body P-ring protein YP_005108174.1 145177 D 1112912 CDS YP_005108175.1 376278142 11686298 146247..146819 1 NC_016775.1 similar to GP:12057224; identified by sequence similarity; putative; hypothetical protein 146819 11686298 BSVBI22_B0155 Brucella suis VBI22 hypothetical protein YP_005108175.1 146247 D 1112912 CDS YP_005108176.1 376278143 11686299 146816..147532 1 NC_016775.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 147532 flgH 11686299 flgH Brucella suis VBI22 flagellar basal body L-ring protein YP_005108176.1 146816 D 1112912 CDS YP_005108177.1 376278144 11686300 147545..148036 1 NC_016775.1 similar to GP:15073597, GB:X56253, GB:X56254, GB:X56255, GB:X56256, GB:X56257, GB:M16985, SP:P20645, PID:307147, and PID:825692; identified by sequence similarity; putative; flagellar protein FliL, putative 148036 11686300 BSVBI22_B0157 Brucella suis VBI22 flagellar protein FliL, putative YP_005108177.1 147545 D 1112912 CDS YP_005108178.1 376278145 11686301 148033..148773 1 NC_016775.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 148773 fliP 11686301 fliP Brucella suis VBI22 flagellar biosynthesis protein FliP YP_005108178.1 148033 D 1112912 CDS YP_005108179.1 376278146 11686302 148868..149362 1 NC_016775.1 hypothetical protein 149362 11686302 BSVBI22_B0159 Brucella suis VBI22 hypothetical protein YP_005108179.1 148868 D 1112912 CDS YP_005108180.1 376278147 11686303 149375..149791 1 NC_016775.1 similar to GP:15130936; identified by sequence similarity; putative; hypothetical protein 149791 11686303 BSVBI22_B0160 Brucella suis VBI22 hypothetical protein YP_005108180.1 149375 D 1112912 CDS YP_005108181.1 376278148 11686304 complement(149987..150871) 1 NC_016775.1 similar to GP:3419687; identified by sequence similarity; putative; LysR family transcriptional regulator 150871 11686304 BSVBI22_B0161 Brucella suis VBI22 LysR family transcriptional regulator YP_005108181.1 149987 R 1112912 CDS YP_005108182.1 376278149 11686305 151051..152268 1 NC_016775.1 identified by match to PFAM protein family HMM PF02515; CAIB/BAIF family protein 152268 11686305 BSVBI22_B0162 Brucella suis VBI22 CAIB/BAIF family protein YP_005108182.1 151051 D 1112912 CDS YP_005108183.1 376278150 11686306 152336..153172 1 NC_016775.1 identified by match to PFAM protein family HMM PF01524; hypothetical protein 153172 11686306 BSVBI22_B0163 Brucella suis VBI22 hypothetical protein YP_005108183.1 152336 D 1112912 CDS YP_005108184.1 376278151 11686307 153166..153990 1 NC_016775.1 identified by match to PFAM protein family HMM PF03328; citrate lyase, beta subunit, putative 153990 11686307 BSVBI22_B0164 Brucella suis VBI22 citrate lyase, beta subunit, putative YP_005108184.1 153166 D 1112912 CDS YP_005108185.1 376278152 11686308 complement(154185..154370) 1 NC_016775.1 hypothetical protein 154370 11686308 BSVBI22_B0165 Brucella suis VBI22 hypothetical protein YP_005108185.1 154185 R 1112912 CDS YP_005108186.1 376278153 11686309 154440..155018 1 NC_016775.1 similar to GB:L25675, PID:409767, and SP:P53641; identified by sequence similarity; putative; cytochrome b561, putative 155018 11686309 BSVBI22_B0166 Brucella suis VBI22 cytochrome b561, putative YP_005108186.1 154440 D 1112912 CDS YP_005108187.1 376278154 11686310 155517..155861 1 NC_016775.1 hypothetical protein 155861 11686310 BSVBI22_B0167 Brucella suis VBI22 hypothetical protein YP_005108187.1 155517 D 1112912 CDS YP_005108188.1 376278155 11686311 155809..156216 1 NC_016775.1 hypothetical protein 156216 11686311 BSVBI22_B0168 Brucella suis VBI22 hypothetical protein YP_005108188.1 155809 D 1112912 CDS YP_005108189.1 376278156 11686312 156261..159602 1 NC_016775.1 similar to GP:15162141, and GP:15162141; identified by sequence similarity; putative; outer membrane autotransporter 159602 11686312 BSVBI22_B0169 Brucella suis VBI22 outer membrane autotransporter YP_005108189.1 156261 D 1112912 CDS YP_005108190.1 376278157 11686313 159838..160233 1 NC_016775.1 similar to GB:L11566, SP:Q07020, PID:337493, GB:L11566, SP:Q07020, and PID:337493; identified by sequence similarity; putative; cytochrome c2 160233 cycA 11686313 cycA Brucella suis VBI22 cytochrome c2 YP_005108190.1 159838 D 1112912 CDS YP_005108191.1 376278158 11686314 complement(160457..160696) 1 NC_016775.1 hypothetical protein 160696 11686314 BSVBI22_B0171 Brucella suis VBI22 hypothetical protein YP_005108191.1 160457 R 1112912 CDS YP_005108192.1 376278159 11686315 161127..161264 1 NC_016775.1 hypothetical protein 161264 11686315 BSVBI22_B0172 Brucella suis VBI22 hypothetical protein YP_005108192.1 161127 D 1112912 CDS YP_005108193.1 376278160 11686316 complement(161342..162154) 1 NC_016775.1 similar to GP:15073704; identified by sequence similarity; putative; GntR family transcriptional regulator 162154 11686316 BSVBI22_B0173 Brucella suis VBI22 GntR family transcriptional regulator YP_005108193.1 161342 R 1112912 CDS YP_005108194.1 376278161 11686317 complement(162276..163196) 1 NC_016775.1 similar to GP:15073706; identified by sequence similarity; putative; LysR family transcriptional regulator 163196 11686317 BSVBI22_B0174 Brucella suis VBI22 LysR family transcriptional regulator YP_005108194.1 162276 R 1112912 CDS YP_005108195.1 376278162 11686318 complement(163356..163475) 1 NC_016775.1 hypothetical protein 163475 11686318 BSVBI22_B0175 Brucella suis VBI22 hypothetical protein YP_005108195.1 163356 R 1112912 CDS YP_005108196.1 376278163 11686319 163547..165043 1 NC_016775.1 similar to SP:P32718, PID:396419, GB:U00096, and PID:1790522; identified by sequence similarity; putative; glycolate oxidase, subunit GlcD 165043 glcD 11686319 glcD Brucella suis VBI22 glycolate oxidase, subunit GlcD YP_005108196.1 163547 D 1112912 CDS YP_005108197.1 376278164 11686320 165059..166291 1 NC_016775.1 similar to GP:14026515, and SP:P52073; identified by sequence similarity; putative; glycolate oxidase, subunit GlcE 166291 glcE 11686320 glcE Brucella suis VBI22 glycolate oxidase, subunit GlcE YP_005108197.1 165059 D 1112912 CDS YP_005108198.1 376278165 11686321 166296..167597 1 NC_016775.1 similar to SP:P52074; identified by sequence similarity; putative; glycolate oxidase, iron-sulfur subunit 167597 glcF 11686321 glcF Brucella suis VBI22 glycolate oxidase, iron-sulfur subunit YP_005108198.1 166296 D 1112912 CDS YP_005108199.1 376278166 11686322 complement(167821..168648) 1 NC_016775.1 similar to GP:4007669; identified by sequence similarity; putative; aldo/keto reductase family oxidoreductase 168648 11686322 BSVBI22_B0179 Brucella suis VBI22 aldo/keto reductase family oxidoreductase YP_005108199.1 167821 R 1112912 CDS YP_005108200.1 376278167 11686323 complement(168924..169658) 1 NC_016775.1 similar to GP:15155625, and GP:15073711; identified by sequence similarity; putative; hypothetical protein 169658 11686323 BSVBI22_B0180 Brucella suis VBI22 hypothetical protein YP_005108200.1 168924 R 1112912 CDS YP_005108201.1 376278168 11686324 169898..170554 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00624; DNA-3-methyladenine glycosidase I 170554 tag 11686324 tag Brucella suis VBI22 DNA-3-methyladenine glycosidase I YP_005108201.1 169898 D 1112912 CDS YP_005108202.1 376278169 11686325 170673..171290 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00948; amino acid transporter LysE 171290 11686325 BSVBI22_B0182 Brucella suis VBI22 amino acid transporter LysE YP_005108202.1 170673 D 1112912 CDS YP_005108203.1 376278170 11686326 171401..172909 1 NC_016775.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 172909 hisS 11686326 hisS Brucella suis VBI22 histidyl-tRNA synthetase YP_005108203.1 171401 D 1112912 CDS YP_005108204.1 376278171 11686327 172918..174048 1 NC_016775.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase regulatory subunit 174048 hisZ 11686327 hisZ Brucella suis VBI22 ATP phosphoribosyltransferase regulatory subunit YP_005108204.1 172918 D 1112912 CDS YP_005108205.1 376278172 11686328 174045..174740 1 NC_016775.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase catalytic subunit 174740 hisG 11686328 hisG Brucella suis VBI22 ATP phosphoribosyltransferase catalytic subunit YP_005108205.1 174045 D 1112912 CDS YP_005108206.1 376278173 11686330 complement(176337..176738) 1 NC_016775.1 hypothetical protein 176738 11686330 BSVBI22_B0187 Brucella suis VBI22 hypothetical protein YP_005108206.1 176337 R 1112912 CDS YP_005108207.1 376278174 11686331 complement(176841..178232) 1 NC_016775.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 178232 fumC 11686331 fumC Brucella suis VBI22 fumarate hydratase YP_005108207.1 176841 R 1112912 CDS YP_005108208.1 376278175 11686332 complement(178382..178669) 1 NC_016775.1 hypothetical protein 178669 11686332 BSVBI22_B0189 Brucella suis VBI22 hypothetical protein YP_005108208.1 178382 R 1112912 CDS YP_005108209.1 376278176 11686333 complement(178966..179187) 1 NC_016775.1 hypothetical protein 179187 11686333 BSVBI22_B0190 Brucella suis VBI22 hypothetical protein YP_005108209.1 178966 R 1112912 CDS YP_005108210.1 376278177 11686334 complement(179389..181029) 1 NC_016775.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 181029 groEL 11686334 groEL Brucella suis VBI22 chaperonin GroEL YP_005108210.1 179389 R 1112912 CDS YP_005108211.1 376278178 11686335 complement(181120..181416) 1 NC_016775.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 181416 groES 11686335 groES Brucella suis VBI22 co-chaperonin GroES YP_005108211.1 181120 R 1112912 CDS YP_005108212.1 376278179 11686336 181536..181676 1 NC_016775.1 hypothetical protein 181676 11686336 BSVBI22_B0193 Brucella suis VBI22 hypothetical protein YP_005108212.1 181536 D 1112912 CDS YP_005108213.1 376278180 11686337 complement(181729..181833) 1 NC_016775.1 hypothetical protein 181833 11686337 BSVBI22_B0194 Brucella suis VBI22 hypothetical protein YP_005108213.1 181729 R 1112912 CDS YP_005108214.1 376278181 11686338 181894..182745 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01668; HAD superfamily hydrolase 182745 11686338 BSVBI22_B0195 Brucella suis VBI22 HAD superfamily hydrolase YP_005108214.1 181894 D 1112912 CDS YP_005108215.1 376278182 11686339 182781..182894 1 NC_016775.1 hypothetical protein 182894 11686339 BSVBI22_B0196 Brucella suis VBI22 hypothetical protein YP_005108215.1 182781 D 1112912 CDS YP_005108216.1 376278183 11686340 182875..183822 1 NC_016775.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 183822 ribF 11686340 ribF Brucella suis VBI22 bifunctional riboflavin kinase/FMN adenylyltransferase YP_005108216.1 182875 D 1112912 CDS YP_005108217.1 376278184 11686341 184166..187084 1 NC_016775.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 187084 ileS 11686341 ileS Brucella suis VBI22 isoleucyl-tRNA synthetase YP_005108217.1 184166 D 1112912 CDS YP_005108218.1 376278185 11686342 187276..187947 1 NC_016775.1 similar to GP:15073729; identified by sequence similarity; putative; hypothetical protein 187947 11686342 BSVBI22_B0199 Brucella suis VBI22 hypothetical protein YP_005108218.1 187276 D 1112912 CDS YP_005108219.1 376278186 11686343 188292..188852 1 NC_016775.1 similar to SP:P08732; identified by sequence similarity; putative; cytochrome b561, putative 188852 11686343 BSVBI22_B0200 Brucella suis VBI22 cytochrome b561, putative YP_005108219.1 188292 D 1112912 CDS YP_005108220.1 376278187 11686344 complement(188906..189379) 1 NC_016775.1 similar to GP:15155649; identified by sequence similarity; putative; cytidine and deoxycytidylate deaminase family protein 189379 11686344 BSVBI22_B0201 Brucella suis VBI22 cytidine and deoxycytidylate deaminase family protein YP_005108220.1 188906 R 1112912 CDS YP_005108221.1 376278188 11686345 189469..191265 1 NC_016775.1 RNA pseudouridylate synthase family protein 191265 11686345 BSVBI22_B0202 Brucella suis VBI22 RNA pseudouridylate synthase family protein YP_005108221.1 189469 D 1112912 CDS YP_005108222.1 376278189 11686346 191246..191809 1 NC_016775.1 identified by match to PFAM protein family HMM PF03602; hypothetical protein 191809 11686346 BSVBI22_B0203 Brucella suis VBI22 hypothetical protein YP_005108222.1 191246 D 1112912 CDS YP_005108223.1 376278190 11686348 194783..195664 1 NC_016775.1 identified by match to PFAM protein family HMM PF01734; hypothetical protein 195664 11686348 BSVBI22_B0205 Brucella suis VBI22 hypothetical protein YP_005108223.1 194783 D 1112912 CDS YP_005108224.1 376278191 11686349 complement(195677..197584) 1 NC_016775.1 similar to GP:15073737; identified by sequence similarity; putative; glutathione-regulated potassium-efflux system protein, putative 197584 11686349 BSVBI22_B0206 Brucella suis VBI22 glutathione-regulated potassium-efflux system protein, putative YP_005108224.1 195677 R 1112912 CDS YP_005108225.1 376278192 11686350 197723..199066 1 NC_016775.1 similar to GB:V00566, GB:J00299, GB:M29386, GB:D00411, SP:P01236, GB:U75583, PID:1620399, PID:1658518, PID:190354, PID:190356, PID:220018, PID:34211, PID:531101, and PID:531103; identified by sequence similarity; putative; pmbA protein 199066 pmbA 11686350 pmbA Brucella suis VBI22 pmbA protein YP_005108225.1 197723 D 1112912 CDS YP_005108226.1 376278193 11686351 199098..199862 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01330; inositol monophosphatase family protein 199862 11686351 BSVBI22_B0208 Brucella suis VBI22 inositol monophosphatase family protein YP_005108226.1 199098 D 1112912 CDS YP_005108227.1 376278194 11686352 199901..200152 1 NC_016775.1 similar to GP:15155658, and GP:15073740; identified by sequence similarity; putative; hypothetical protein 200152 11686352 BSVBI22_B0209 Brucella suis VBI22 hypothetical protein YP_005108227.1 199901 D 1112912 CDS YP_005108228.1 376278195 11686353 200216..200959 1 NC_016775.1 similar to GP:14027592; identified by sequence similarity; putative; hypothetical protein 200959 11686353 BSVBI22_B0210 Brucella suis VBI22 hypothetical protein YP_005108228.1 200216 D 1112912 CDS YP_005108229.1 376278196 11686354 200956..202296 1 NC_016775.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 202296 kdtA 11686354 kdtA Brucella suis VBI22 3-deoxy-D-manno-octulosonic-acid transferase YP_005108229.1 200956 D 1112912 CDS YP_005108230.1 376278197 11686355 202299..203324 1 NC_016775.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 203324 lpxK 11686355 lpxK Brucella suis VBI22 tetraacyldisaccharide 4'-kinase YP_005108230.1 202299 D 1112912 CDS YP_005108231.1 376278198 11686356 complement(203338..203574) 1 NC_016775.1 similar to GP:15073746; identified by sequence similarity; putative; hypothetical protein 203574 11686356 BSVBI22_B0213 Brucella suis VBI22 hypothetical protein YP_005108231.1 203338 R 1112912 CDS YP_005108232.1 376278199 11686357 complement(203672..205543) 1 NC_016775.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 205543 mutL 11686357 mutL Brucella suis VBI22 DNA mismatch repair protein YP_005108232.1 203672 R 1112912 CDS YP_005108233.1 376278200 11686358 complement(205727..207010) 1 NC_016775.1 similar to GB:Z25795, SP:P39118, PID:397488, PID:2293136, GB:AL009126, GB:Z25795, SP:P39118, PID:397488, PID:2293136, and GB:AL009126; identified by sequence similarity; putative; cis,cis-muconate transport protein MucK 207010 mucK 11686358 mucK Brucella suis VBI22 cis,cis-muconate transport protein MucK YP_005108233.1 205727 R 1112912 CDS YP_005108234.1 376278201 11686359 complement(207108..208262) 1 NC_016775.1 similar to SP:P45857; identified by sequence similarity; putative; acyl-CoA dehydrogenase 208262 11686359 BSVBI22_B0216 Brucella suis VBI22 acyl-CoA dehydrogenase YP_005108234.1 207108 R 1112912 CDS YP_005108235.1 376278202 11686360 complement(208319..209173) 1 NC_016775.1 identified by match to PFAM protein family HMM PF01614; IclR family transcriptional regulator 209173 11686360 BSVBI22_B0217 Brucella suis VBI22 IclR family transcriptional regulator YP_005108235.1 208319 R 1112912 CDS YP_005108236.1 376278203 11686361 209433..210194 1 NC_016775.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 210194 11686361 BSVBI22_B0218 Brucella suis VBI22 enoyl-CoA hydratase YP_005108236.1 209433 D 1112912 CDS YP_005108237.1 376278204 11686362 210199..211728 1 NC_016775.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxy-acyl-CoA dehydrogenase 211728 11686362 BSVBI22_B0219 Brucella suis VBI22 3-hydroxy-acyl-CoA dehydrogenase YP_005108237.1 210199 D 1112912 CDS YP_005108238.1 376278205 11686363 211951..213192 1 NC_016775.1 similar to GP:14587414; identified by sequence similarity; putative; CAIB/BAIF family protein 213192 11686363 BSVBI22_B0220 Brucella suis VBI22 CAIB/BAIF family protein YP_005108238.1 211951 D 1112912 CDS YP_005108239.1 376278206 11686365 214430..214894 1 NC_016775.1 identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator 214894 11686365 BSVBI22_B0222 Brucella suis VBI22 MerR family transcriptional regulator YP_005108239.1 214430 D 1112912 CDS YP_005108240.1 376278207 11686366 complement(214940..215647) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01382; ThiJ/PfpI family protein 215647 11686366 BSVBI22_B0223 Brucella suis VBI22 ThiJ/PfpI family protein YP_005108240.1 214940 R 1112912 CDS YP_005108241.1 376278208 11686367 complement(215878..217218) 1 NC_016775.1 similar to GP:15159266; identified by sequence similarity; putative; sensor histidine kinase 217218 11686367 BSVBI22_B0224 Brucella suis VBI22 sensor histidine kinase YP_005108241.1 215878 R 1112912 CDS YP_005108242.1 376278209 11686369 complement(218014..218178) 1 NC_016775.1 hypothetical protein 218178 11686369 BSVBI22_B0226 Brucella suis VBI22 hypothetical protein YP_005108242.1 218014 R 1112912 CDS YP_005108243.1 376278210 11686370 218150..218422 1 NC_016775.1 hypothetical protein 218422 11686370 BSVBI22_B0227 Brucella suis VBI22 hypothetical protein YP_005108243.1 218150 D 1112912 CDS YP_005108244.1 376278211 11686371 218590..219060 1 NC_016775.1 hypothetical protein 219060 11686371 BSVBI22_B0228 Brucella suis VBI22 hypothetical protein YP_005108244.1 218590 D 1112912 CDS YP_005108245.1 376278212 11686372 219071..221275 1 NC_016775.1 identified by match to PFAM protein family HMM PF03929; oxidoreductase, FAD-binding, putative 221275 11686372 BSVBI22_B0229 Brucella suis VBI22 oxidoreductase, FAD-binding, putative YP_005108245.1 219071 D 1112912 CDS YP_005108246.1 376278213 11686373 221256..222233 1 NC_016775.1 similar to SP:P41780; identified by sequence similarity; putative; ApbE family protein 222233 11686373 BSVBI22_B0230 Brucella suis VBI22 ApbE family protein YP_005108246.1 221256 D 1112912 CDS YP_005108247.1 376278214 11686374 complement(222276..223451) 1 NC_016775.1 similar to GP:15073890; identified by sequence similarity; putative; GAF/GGDEF domain-containing protein 223451 11686374 BSVBI22_B0231 Brucella suis VBI22 GAF/GGDEF domain-containing protein YP_005108247.1 222276 R 1112912 CDS YP_005108248.1 376278215 11686375 complement(223734..224627) 1 NC_016775.1 similar to GP:15159282; identified by sequence similarity; putative; hypothetical protein 224627 11686375 BSVBI22_B0232 Brucella suis VBI22 hypothetical protein YP_005108248.1 223734 R 1112912 CDS YP_005108249.1 376278216 11686376 224603..224743 1 NC_016775.1 hypothetical protein 224743 11686376 BSVBI22_B0233 Brucella suis VBI22 hypothetical protein YP_005108249.1 224603 D 1112912 CDS YP_005108250.1 376278217 11686377 224867..225544 1 NC_016775.1 similar to GP:15140120; identified by sequence similarity; putative; GntR family transcriptional regulator 225544 11686377 BSVBI22_B0234 Brucella suis VBI22 GntR family transcriptional regulator YP_005108250.1 224867 D 1112912 CDS YP_005108251.1 376278218 11686378 225645..226607 1 NC_016775.1 similar to GP:15140121; identified by sequence similarity; putative; dihydrodipicolinate synthase family protein 226607 11686378 BSVBI22_B0235 Brucella suis VBI22 dihydrodipicolinate synthase family protein YP_005108251.1 225645 D 1112912 CDS YP_005108252.1 376278219 11686379 complement(226670..227707) 1 NC_016775.1 similar to GP:15140123; identified by sequence similarity; putative; malate/L-lactate dehydrogenase family protein 227707 11686379 BSVBI22_B0236 Brucella suis VBI22 malate/L-lactate dehydrogenase family protein YP_005108252.1 226670 R 1112912 CDS YP_005108253.1 376278220 11686380 complement(227721..227822) 1 NC_016775.1 hypothetical protein 227822 11686380 BSVBI22_B0237 Brucella suis VBI22 hypothetical protein YP_005108253.1 227721 R 1112912 CDS YP_005108254.1 376278221 11686381 complement(227826..227924) 1 NC_016775.1 hypothetical protein 227924 11686381 BSVBI22_B0238 Brucella suis VBI22 hypothetical protein YP_005108254.1 227826 R 1112912 CDS YP_005108255.1 376278222 11686382 227944..229212 1 NC_016775.1 identified by match to PFAM protein family HMM PF03772; hypothetical protein 229212 11686382 BSVBI22_B0239 Brucella suis VBI22 hypothetical protein YP_005108255.1 227944 D 1112912 CDS YP_005108256.1 376278223 11686383 complement(229220..229693) 1 NC_016775.1 similar to GP:6978955; identified by sequence similarity; putative; hypothetical protein 229693 11686383 BSVBI22_B0240 Brucella suis VBI22 hypothetical protein YP_005108256.1 229220 R 1112912 CDS YP_005108257.1 376278224 11686384 complement(229750..229905) 1 NC_016775.1 similar to GP:6978956, and GP:6978956; identified by sequence similarity; putative; hypothetical protein 229905 11686384 BSVBI22_B0241 Brucella suis VBI22 hypothetical protein YP_005108257.1 229750 R 1112912 CDS YP_005108258.1 376278225 11686385 230009..230578 1 NC_016775.1 similar to GP:6978957; identified by sequence similarity; putative; cytochrome c oxidase, subunit III 230578 11686385 BSVBI22_B0242 Brucella suis VBI22 cytochrome c oxidase, subunit III YP_005108258.1 230009 D 1112912 CDS YP_005108259.1 376278226 11686386 230586..230864 1 NC_016775.1 similar to GP:6978958, and GP:6978958; identified by sequence similarity; putative; norF protein 230864 norF 11686386 norF Brucella suis VBI22 norF protein YP_005108259.1 230586 D 1112912 CDS YP_005108260.1 376278227 11686387 231024..231476 1 NC_016775.1 similar to GP:6978959, and SP:Q51662; identified by sequence similarity; putative; nitric-oxide reductase, small subunit 231476 norC 11686387 norC Brucella suis VBI22 nitric-oxide reductase, small subunit YP_005108260.1 231024 D 1112912 CDS YP_005108261.1 376278228 11686388 231502..232851 1 NC_016775.1 similar to GP:6978960, and SP:P98008; identified by sequence similarity; putative; nitric-oxide reductase, large subunit 232851 norB 11686388 norB Brucella suis VBI22 nitric-oxide reductase, large subunit YP_005108261.1 231502 D 1112912 CDS YP_005108262.1 376278229 11686389 232942..233754 1 NC_016775.1 similar to GP:6978961, GB:U10072, SP:P98177, and PID:501087; identified by sequence similarity; putative; CbbQ/NirQ/NorQ/GpvN family protein 233754 11686389 BSVBI22_B0246 Brucella suis VBI22 CbbQ/NirQ/NorQ/GpvN family protein YP_005108262.1 232942 D 1112912 CDS YP_005108263.1 376278230 11686390 233766..235667 1 NC_016775.1 similar to GP:6978962, GB:K00396, GB:M10065, GB:M12529, GB:X00199, GB:Z70760, GB:X92000, SP:P02649, PID:1263123, PID:178849, PID:178851, PID:178853, PID:579590, and PID:929610; identified by sequence similarity; putative; norD protein 235667 norD 11686390 norD Brucella suis VBI22 norD protein YP_005108263.1 233766 D 1112912 CDS YP_005108264.1 376278231 11686391 235847..236131 1 NC_016775.1 similar to GP:14523804; identified by sequence similarity; putative; hypothetical protein 236131 11686391 BSVBI22_B0248 Brucella suis VBI22 hypothetical protein YP_005108264.1 235847 D 1112912 CDS YP_005108265.1 376278232 11686392 236167..237534 1 NC_016775.1 similar to GP:14523803, and GP:14523803; identified by sequence similarity; putative; hypothetical protein 237534 11686392 BSVBI22_B0249 Brucella suis VBI22 hypothetical protein YP_005108265.1 236167 D 1112912 CDS YP_005108266.1 376278233 11686393 237531..238058 1 NC_016775.1 similar to GP:14523802, and GP:14523802; identified by sequence similarity; putative; hypothetical protein 238058 11686393 BSVBI22_B0250 Brucella suis VBI22 hypothetical protein YP_005108266.1 237531 D 1112912 CDS YP_005108267.1 376278234 11686394 238065..238391 1 NC_016775.1 similar to GP:14523801, and GP:14523801; identified by sequence similarity; putative; hypothetical protein 238391 11686394 BSVBI22_B0251 Brucella suis VBI22 hypothetical protein YP_005108267.1 238065 D 1112912 CDS YP_005108268.1 376278235 11686395 238515..239690 1 NC_016775.1 similar to GP:15156967, and GP:15156967; identified by sequence similarity; putative; hypothetical protein 239690 11686395 BSVBI22_B0252 Brucella suis VBI22 hypothetical protein YP_005108268.1 238515 D 1112912 CDS YP_005108269.1 376278236 11686396 239687..240271 1 NC_016775.1 similar to GP:15074522, and GP:15074522; identified by sequence similarity; putative; hypothetical protein 240271 11686396 BSVBI22_B0253 Brucella suis VBI22 hypothetical protein YP_005108269.1 239687 D 1112912 CDS YP_005108270.1 376278237 11686397 240222..240920 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01409; hypothetical protein 240920 11686397 BSVBI22_B0254 Brucella suis VBI22 hypothetical protein YP_005108270.1 240222 D 1112912 CDS YP_005108271.1 376278238 11686398 240996..241145 1 NC_016775.1 hypothetical protein 241145 11686398 BSVBI22_B0255 Brucella suis VBI22 hypothetical protein YP_005108271.1 240996 D 1112912 CDS YP_005108272.1 376278239 11686399 241276..242406 1 NC_016775.1 similar to GB:J05016, SP:P13667, PID:181508, GB:J05016, SP:P13667, and PID:181508; identified by sequence similarity; putative; copper-containing nitrite reductase 242406 11686399 BSVBI22_B0256 Brucella suis VBI22 copper-containing nitrite reductase YP_005108272.1 241276 D 1112912 CDS YP_005108273.1 376278240 11686400 242539..243459 1 NC_016775.1 similar to GP:14523796, and GP:2773329; identified by sequence similarity; putative; NirV protein, putative 243459 11686400 BSVBI22_B0257 Brucella suis VBI22 NirV protein, putative YP_005108273.1 242539 D 1112912 CDS YP_005108274.1 376278241 11686401 243560..244255 1 NC_016775.1 similar to GP:6978954; identified by sequence similarity; putative; Crp/FNR family transcriptional regulator 244255 11686401 BSVBI22_B0258 Brucella suis VBI22 Crp/FNR family transcriptional regulator YP_005108274.1 243560 D 1112912 CDS YP_005108275.1 376278242 11686402 244338..245393 1 NC_016775.1 similar to GP:15140338; identified by sequence similarity; putative; LacI family sugar-binding transcriptional regulator 245393 11686402 BSVBI22_B0259 Brucella suis VBI22 LacI family sugar-binding transcriptional regulator YP_005108275.1 244338 D 1112912 CDS YP_005108276.1 376278243 11686403 complement(245574..245795) 1 NC_016775.1 hypothetical protein 245795 11686403 BSVBI22_B0260 Brucella suis VBI22 hypothetical protein YP_005108276.1 245574 R 1112912 CDS YP_005108277.1 376278244 11686404 245794..246846 1 NC_016775.1 similar to GP:2661681; identified by sequence similarity; putative; sugar ABC transporter, periplasmic sugar-binding protein, putative 246846 11686404 BSVBI22_B0261 Brucella suis VBI22 sugar ABC transporter, periplasmic sugar-binding protein, putative YP_005108277.1 245794 D 1112912 CDS YP_005108278.1 376278245 11686405 247151..248011 1 NC_016775.1 similar to GP:2661682, and GP:12659326; identified by sequence similarity; putative; sugar ABC transporter, ATP-binding protein, putative 248011 11686405 BSVBI22_B0262 Brucella suis VBI22 sugar ABC transporter, ATP-binding protein, putative YP_005108278.1 247151 D 1112912 CDS YP_005108279.1 376278246 11686406 248008..249246 1 NC_016775.1 similar to GP:2661683, and GP:2661683; identified by sequence similarity; putative; sugar ABC transporter, permease protein 249246 11686406 BSVBI22_B0263 Brucella suis VBI22 sugar ABC transporter, permease protein YP_005108279.1 248008 D 1112912 CDS YP_005108280.1 376278247 11686407 249533..250261 1 NC_016775.1 similar to GP:11036625, GB:M57506, GB:M57502, SP:P22362, PID:184506, and PID:339729; identified by sequence similarity; putative; ribitol dehydrogenase 250261 11686407 BSVBI22_B0264 Brucella suis VBI22 ribitol dehydrogenase YP_005108280.1 249533 D 1112912 CDS YP_005108281.1 376278248 11686408 250274..251878 1 NC_016775.1 similar to GP:15158921; identified by sequence similarity; putative; ribitol kinase 251878 11686408 BSVBI22_B0265 Brucella suis VBI22 ribitol kinase YP_005108281.1 250274 D 1112912 CDS YP_005108282.1 376278249 11686409 complement(252010..252675) 1 NC_016775.1 similar to GP:15158337, and GP:15158337; identified by sequence similarity; putative; hypothetical protein 252675 11686409 BSVBI22_B0266 Brucella suis VBI22 hypothetical protein YP_005108282.1 252010 R 1112912 CDS YP_005108283.1 376278250 11686410 complement(252672..253148) 1 NC_016775.1 similar to SP:P08500, GB:M18576, PID:551957, PID:581499, SP:P08500, GB:M18576, PID:551957, and PID:581499; identified by sequence similarity; putative; hypothetical protein 253148 11686410 BSVBI22_B0267 Brucella suis VBI22 hypothetical protein YP_005108283.1 252672 R 1112912 CDS YP_005108284.1 376278251 11686412 255443..255682 1 NC_016775.1 hypothetical protein 255682 11686412 BSVBI22_B0269 Brucella suis VBI22 hypothetical protein YP_005108284.1 255443 D 1112912 CDS YP_005108285.1 376278252 11686413 255695..258058 1 NC_016775.1 similar to GP:14523755; identified by sequence similarity; putative; transcriptional regulator NosR, putative 258058 11686413 BSVBI22_B0270 Brucella suis VBI22 transcriptional regulator NosR, putative YP_005108285.1 255695 D 1112912 CDS YP_005108286.1 376278253 11686414 258079..259998 1 NC_016775.1 reduces nitrous oxide to nitrogen; nitrous-oxide reductase 259998 nosZ 11686414 nosZ Brucella suis VBI22 nitrous-oxide reductase YP_005108286.1 258079 D 1112912 CDS YP_005108287.1 376278254 11686415 260004..261398 1 NC_016775.1 similar to SP:P19843, GB:X04803, SP:P02248, PID:1304128, PID:1490419, PID:340058, PID:340068, and PID:825728; identified by sequence similarity; putative; copper ABC transporter, periplasmic copper-binding protein 261398 nosD 11686415 nosD Brucella suis VBI22 copper ABC transporter, periplasmic copper-binding protein YP_005108287.1 260004 D 1112912 CDS YP_005108288.1 376278255 11686416 261436..262386 1 NC_016775.1 similar to SP:P19844, GB:X04803, SP:P02248, PID:1304128, PID:1490419, PID:340058, PID:340068, and PID:825728; identified by sequence similarity; putative; copper ABC transporter, ATP-binding protein 262386 nosF 11686416 nosF Brucella suis VBI22 copper ABC transporter, ATP-binding protein YP_005108288.1 261436 D 1112912 CDS YP_005108289.1 376278256 11686417 262383..263213 1 NC_016775.1 similar to GP:2177176, GB:L06175, and PID:189449; identified by sequence similarity; putative; nitrous-oxide reductase, nosY component 263213 nosY 11686417 nosY Brucella suis VBI22 nitrous-oxide reductase, nosY component YP_005108289.1 262383 D 1112912 CDS YP_005108290.1 376278257 11686418 263210..263749 1 NC_016775.1 similar to GP:2177177; identified by sequence similarity; putative; protein disulfide isomerase NosL, putative 263749 11686418 BSVBI22_B0275 Brucella suis VBI22 protein disulfide isomerase NosL, putative YP_005108290.1 263210 D 1112912 CDS YP_005108291.1 376278258 11686419 263761..264753 1 NC_016775.1 similar to GP:14523761, and GP:2177178; identified by sequence similarity; putative; nosX protein 264753 11686419 BSVBI22_B0276 Brucella suis VBI22 nosX protein YP_005108291.1 263761 D 1112912 CDS YP_005108292.1 376278259 11686420 264868..265566 1 NC_016775.1 similar to GP:15158856, GB:L06214, PID:153222, and PID:886941; identified by sequence similarity; putative; transcriptional regulator NnrR 265566 nnrR 11686420 nnrR Brucella suis VBI22 transcriptional regulator NnrR YP_005108292.1 264868 D 1112912 CDS YP_005108293.1 376278260 11686421 265704..266144 1 NC_016775.1 pseudoazurin 266144 11686421 BSVBI22_B0278 Brucella suis VBI22 pseudoazurin YP_005108293.1 265704 D 1112912 CDS YP_005108294.1 376278261 11686422 266195..267436 1 NC_016775.1 similar to GP:15158853, and GP:14523798; identified by sequence similarity; putative; hypothetical protein 267436 11686422 BSVBI22_B0279 Brucella suis VBI22 hypothetical protein YP_005108294.1 266195 D 1112912 CDS YP_005108295.1 376278262 11686423 complement(267510..268550) 1 NC_016775.1 ABC transporter, periplasmic binding protein, putative 268550 11686423 BSVBI22_B0280 Brucella suis VBI22 ABC transporter, periplasmic binding protein, putative YP_005108295.1 267510 R 1112912 CDS YP_005108296.1 376278263 11686424 complement(268576..269367) 1 NC_016775.1 similar to GP:15158995; identified by sequence similarity; putative; ABC transporter, permease protein 269367 11686424 BSVBI22_B0281 Brucella suis VBI22 ABC transporter, permease protein YP_005108296.1 268576 R 1112912 CDS YP_005108297.1 376278264 11686425 complement(269364..270209) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00972; ABC transporter, ATP binding protein 270209 11686425 BSVBI22_B0282 Brucella suis VBI22 ABC transporter, ATP binding protein YP_005108297.1 269364 R 1112912 CDS YP_005108298.1 376278265 11686426 270236..270538 1 NC_016775.1 hypothetical protein 270538 11686426 BSVBI22_B0283 Brucella suis VBI22 hypothetical protein YP_005108298.1 270236 D 1112912 CDS YP_005108299.1 376278266 11686427 complement(270444..270587) 1 NC_016775.1 hypothetical protein 270587 11686427 BSVBI22_B0284 Brucella suis VBI22 hypothetical protein YP_005108299.1 270444 R 1112912 CDS YP_005108300.1 376278267 11686428 complement(270636..271568) 1 NC_016775.1 similar to GP:15158836; identified by sequence similarity; putative; protease, putative 271568 11686428 BSVBI22_B0285 Brucella suis VBI22 protease, putative YP_005108300.1 270636 R 1112912 CDS YP_005108301.1 376278268 11686429 complement(271571..272548) 1 NC_016775.1 similar to GP:15158837; identified by sequence similarity; putative; U32 family peptidase 272548 11686429 BSVBI22_B0286 Brucella suis VBI22 U32 family peptidase YP_005108301.1 271571 R 1112912 CDS YP_005108302.1 376278269 11686430 complement(272539..273063) 1 NC_016775.1 similar to GP:15158838, and GP:15158838; identified by sequence similarity; putative; hypothetical protein 273063 11686430 BSVBI22_B0287 Brucella suis VBI22 hypothetical protein YP_005108302.1 272539 R 1112912 CDS YP_005108303.1 376278270 11686431 273177..274691 1 NC_016775.1 similar to GP:14523816; identified by sequence similarity; putative; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 274691 ubiD 11686431 ubiD Brucella suis VBI22 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_005108303.1 273177 D 1112912 CDS YP_005108304.1 376278271 11686432 274688..275278 1 NC_016775.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 275278 11686432 BSVBI22_B0289 Brucella suis VBI22 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_005108304.1 274688 D 1112912 CDS YP_005108305.1 376278272 11686433 complement(275288..275824) 1 NC_016775.1 hypothetical protein 275824 11686433 BSVBI22_B0290 Brucella suis VBI22 hypothetical protein YP_005108305.1 275288 R 1112912 CDS YP_005108306.1 376278273 11686434 complement(275821..276756) 1 NC_016775.1 peptidyl-prolyl cis-trans isomerase, putative 276756 11686434 BSVBI22_B0291 Brucella suis VBI22 peptidyl-prolyl cis-trans isomerase, putative YP_005108306.1 275821 R 1112912 CDS YP_005108307.1 376278274 11686435 complement(276762..277487) 1 NC_016775.1 similar to GB:M64929, SP:Q00005, SP:Q00007, and PID:190422; identified by sequence similarity; putative; respiratory nitrate reductase, gamma subunit 277487 narI 11686435 narI Brucella suis VBI22 respiratory nitrate reductase, gamma subunit YP_005108307.1 276762 R 1112912 CDS YP_005108308.1 376278275 11686436 complement(277498..278205) 1 NC_016775.1 similar to GP:11344603, GB:L08239, and PID:950412; identified by sequence similarity; putative; respiratory nitrate reductase, delta subunit 278205 narJ 11686436 narJ Brucella suis VBI22 respiratory nitrate reductase, delta subunit YP_005108308.1 277498 R 1112912 CDS YP_005108309.1 376278276 11686437 complement(278205..279743) 1 NC_016775.1 similar to GB:D90359, GB:M73442, GB:M73444, GB:X07024, SP:P21675, and PID:29733; identified by sequence similarity; putative; respiratory nitrate reductase, beta subunit 279743 narH 11686437 narH Brucella suis VBI22 respiratory nitrate reductase, beta subunit YP_005108309.1 278205 R 1112912 CDS YP_005108310.1 376278277 11686438 complement(279740..283504) 1 NC_016775.1 similar to SP:P09152; identified by sequence similarity; putative; respiratory nitrate reductase, alpha subunit 283504 narG 11686438 narG Brucella suis VBI22 respiratory nitrate reductase, alpha subunit YP_005108310.1 279740 R 1112912 CDS YP_005108311.1 376278278 11686439 complement(283528..286215) 1 NC_016775.1 similar to GP:14348603; identified by sequence similarity; putative; nitrite extrusion protein 286215 narK 11686439 narK Brucella suis VBI22 nitrite extrusion protein YP_005108311.1 283528 R 1112912 CDS YP_005108312.1 376278279 11686440 286505..287215 1 NC_016775.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism; transcriptional activator FtrB 287215 ftrB 11686440 ftrB Brucella suis VBI22 transcriptional activator FtrB YP_005108312.1 286505 D 1112912 CDS YP_005108313.1 376278280 11686441 complement(287270..288286) 1 NC_016775.1 similar to GP:5802909; identified by sequence similarity; putative; sugar-binding protein, putative 288286 11686441 BSVBI22_B0298 Brucella suis VBI22 sugar-binding protein, putative YP_005108313.1 287270 R 1112912 CDS YP_005108314.1 376278281 11686442 complement(288294..288410) 1 NC_016775.1 hypothetical protein 288410 11686442 BSVBI22_B0299 Brucella suis VBI22 hypothetical protein YP_005108314.1 288294 R 1112912 CDS YP_005108315.1 376278282 11686443 288637..289902 1 NC_016775.1 similar to GP:5802910, and GP:2828820; identified by sequence similarity; putative; sugar ABC transporter, periplasmic sugar-binding protein 289902 11686443 BSVBI22_B0300 Brucella suis VBI22 sugar ABC transporter, periplasmic sugar-binding protein YP_005108315.1 288637 D 1112912 CDS YP_005108316.1 376278283 11686444 289979..290956 1 NC_016775.1 similar to GP:5802911, and GP:2828821; identified by sequence similarity; putative; sugar ABC transporter, permease protein 290956 11686444 BSVBI22_B0301 Brucella suis VBI22 sugar ABC transporter, permease protein YP_005108316.1 289979 D 1112912 CDS YP_005108317.1 376278284 11686445 290959..291786 1 NC_016775.1 similar to GP:5802912, and GP:13517311; identified by sequence similarity; putative; sugar ABC transporter, permease protein 291786 11686445 BSVBI22_B0302 Brucella suis VBI22 sugar ABC transporter, permease protein YP_005108317.1 290959 D 1112912 CDS YP_005108318.1 376278285 11686446 291793..292794 1 NC_016775.1 similar to GP:5802913; identified by sequence similarity; putative; sugar ABC transporter, ATP-binding protein 292794 11686446 BSVBI22_B0303 Brucella suis VBI22 sugar ABC transporter, ATP-binding protein YP_005108318.1 291793 D 1112912 CDS YP_005108319.1 376278286 11686447 292833..293642 1 NC_016775.1 similar to GP:5802914; identified by sequence similarity; putative; hypothetical protein 293642 11686447 BSVBI22_B0304 Brucella suis VBI22 hypothetical protein YP_005108319.1 292833 D 1112912 CDS YP_005108320.1 376278287 11686448 293651..294697 1 NC_016775.1 similar to GP:5802915; identified by sequence similarity; putative; Gfo/Idh/MocA family oxidoreductase 294697 11686448 BSVBI22_B0305 Brucella suis VBI22 Gfo/Idh/MocA family oxidoreductase YP_005108320.1 293651 D 1112912 CDS YP_005108321.1 376278288 11686449 294934..295431 1 NC_016775.1 hypothetical protein 295431 11686449 BSVBI22_B0306 Brucella suis VBI22 hypothetical protein YP_005108321.1 294934 D 1112912 CDS YP_005108322.1 376278289 11686450 295745..297373 1 NC_016775.1 similar to GP:15073164, and GP:12055084; identified by sequence similarity; putative; transporter, putative 297373 11686450 BSVBI22_B0307 Brucella suis VBI22 transporter, putative YP_005108322.1 295745 D 1112912 CDS YP_005108323.1 376278290 11686451 297360..297476 1 NC_016775.1 hypothetical protein 297476 11686451 BSVBI22_B0308 Brucella suis VBI22 hypothetical protein YP_005108323.1 297360 D 1112912 CDS YP_005108324.1 376278291 11686452 complement(297530..297856) 1 NC_016775.1 hypothetical protein 297856 11686452 BSVBI22_B0309 Brucella suis VBI22 hypothetical protein YP_005108324.1 297530 R 1112912 CDS YP_005108325.1 376278292 11686453 298050..298271 1 NC_016775.1 similar to GP:1800061; identified by sequence similarity; putative; glutaredoxin-like protein nrdH 298271 nrdH 11686453 nrdH Brucella suis VBI22 glutaredoxin-like protein nrdH YP_005108325.1 298050 D 1112912 CDS YP_005108326.1 376278293 11686454 298285..298692 1 NC_016775.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 298692 nrdI 11686454 nrdI Brucella suis VBI22 ribonucleotide reductase stimulatory protein YP_005108326.1 298285 D 1112912 CDS YP_005108327.1 376278294 11686455 298743..300884 1 NC_016775.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 300884 nrdE 11686455 nrdE Brucella suis VBI22 ribonucleotide-diphosphate reductase subunit alpha YP_005108327.1 298743 D 1112912 CDS YP_005108328.1 376278295 11686456 300899..301888 1 NC_016775.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 301888 nrdF 11686456 nrdF Brucella suis VBI22 ribonucleotide-diphosphate reductase subunit beta YP_005108328.1 300899 D 1112912 CDS YP_005108329.1 376278296 11686457 complement(302058..302282) 1 NC_016775.1 hypothetical protein 302282 11686457 BSVBI22_B0314 Brucella suis VBI22 hypothetical protein YP_005108329.1 302058 R 1112912 CDS YP_005108330.1 376278297 11686458 302416..302508 1 NC_016775.1 hypothetical protein 302508 11686458 BSVBI22_B0315 Brucella suis VBI22 hypothetical protein YP_005108330.1 302416 D 1112912 CDS YP_005108331.1 376278298 11686459 302493..302624 1 NC_016775.1 hypothetical protein 302624 11686459 BSVBI22_B0316 Brucella suis VBI22 hypothetical protein YP_005108331.1 302493 D 1112912 CDS YP_005108332.1 376278299 11686460 302754..303515 1 NC_016775.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 303515 minC 11686460 minC Brucella suis VBI22 septum formation inhibitor YP_005108332.1 302754 D 1112912 CDS YP_005108333.1 376278300 11686461 303543..304358 1 NC_016775.1 similar to GP:15160138, and SP:P18197; identified by sequence similarity; putative; septum site-determining protein MinD 304358 minD 11686461 minD Brucella suis VBI22 septum site-determining protein MinD YP_005108333.1 303543 D 1112912 CDS YP_005108334.1 376278301 11686462 304355..304627 1 NC_016775.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 304627 minE 11686462 minE Brucella suis VBI22 cell division topological specificity factor MinE YP_005108334.1 304355 D 1112912 CDS YP_005108335.1 376278302 11686463 304671..304838 1 NC_016775.1 hypothetical protein 304838 11686463 BSVBI22_B0320 Brucella suis VBI22 hypothetical protein YP_005108335.1 304671 D 1112912 CDS YP_005108336.1 376278303 11686465 complement(305167..305559) 1 NC_016775.1 similar to GP:15159179, and GP:15159179; identified by sequence similarity; putative; hypothetical protein 305559 11686465 BSVBI22_B0321 Brucella suis VBI22 hypothetical protein YP_005108336.1 305167 R 1112912 CDS YP_005108337.1 376278304 11686466 305935..306981 1 NC_016775.1 similar to GP:14524112, and GP:17428750; identified by sequence similarity; putative; spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein, putative 306981 11686466 BSVBI22_B0322 Brucella suis VBI22 spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein, putative YP_005108337.1 305935 D 1112912 CDS YP_005108338.1 376278305 11686467 307055..308122 1 NC_016775.1 similar to GP:14524111; identified by sequence similarity; putative; spermidine/putrescine ABC transporter, ATP-binding protein, putative 308122 11686467 BSVBI22_B0323 Brucella suis VBI22 spermidine/putrescine ABC transporter, ATP-binding protein, putative YP_005108338.1 307055 D 1112912 CDS YP_005108339.1 376278306 11686468 308056..309294 1 NC_016775.1 similar to GP:14524110, and SP:P23860; identified by sequence similarity; putative; spermidine/putrescine ABC transporter, permease protein, putative 309294 11686468 BSVBI22_B0324 Brucella suis VBI22 spermidine/putrescine ABC transporter, permease protein, putative YP_005108339.1 308056 D 1112912 CDS YP_005108340.1 376278307 11686469 309297..310073 1 NC_016775.1 similar to GP:14524109, GB:X59932, SP:P41240, PID:30256, and PID:30315; identified by sequence similarity; putative; spermidine/putrescine ABC transporter, permease protein 310073 11686469 BSVBI22_B0325 Brucella suis VBI22 spermidine/putrescine ABC transporter, permease protein YP_005108340.1 309297 D 1112912 CDS YP_005108341.1 376278308 11686470 310385..310564 1 NC_016775.1 hypothetical protein 310564 11686470 BSVBI22_B0326 Brucella suis VBI22 hypothetical protein YP_005108341.1 310385 D 1112912 CDS YP_005108342.1 376278309 11686471 310561..310785 1 NC_016775.1 hypothetical protein 310785 11686471 BSVBI22_B0327 Brucella suis VBI22 hypothetical protein YP_005108342.1 310561 D 1112912 CDS YP_005108343.1 376278310 11686472 311022..311549 1 NC_016775.1 hypothetical protein 311549 11686472 BSVBI22_B0328 Brucella suis VBI22 hypothetical protein YP_005108343.1 311022 D 1112912 CDS YP_005108344.1 376278311 11686473 complement(311691..312191) 1 NC_016775.1 hypothetical protein 312191 11686473 BSVBI22_B0329 Brucella suis VBI22 hypothetical protein YP_005108344.1 311691 R 1112912 CDS YP_005108345.1 376278312 11686474 complement(312188..315412) 1 NC_016775.1 similar to GP:15141215; identified by sequence similarity; putative; hydrophobe/amphiphile efflux-1 family protein 315412 11686474 BSVBI22_B0330 Brucella suis VBI22 hydrophobe/amphiphile efflux-1 family protein YP_005108345.1 312188 R 1112912 CDS YP_005108346.1 376278313 11686475 complement(315416..316651) 1 NC_016775.1 similar to GP:14524048; identified by sequence similarity; putative; HlyD family secretion protein 316651 11686475 BSVBI22_B0331 Brucella suis VBI22 HlyD family secretion protein YP_005108346.1 315416 R 1112912 CDS YP_005108347.1 376278314 11686476 complement(316837..317370) 1 NC_016775.1 hypothetical protein 317370 11686476 BSVBI22_B0332 Brucella suis VBI22 hypothetical protein YP_005108347.1 316837 R 1112912 CDS YP_005108348.1 376278315 11686477 complement(317445..317618) 1 NC_016775.1 hypothetical protein 317618 11686477 BSVBI22_B0333 Brucella suis VBI22 hypothetical protein YP_005108348.1 317445 R 1112912 CDS YP_005108349.1 376278316 11686480 321104..322057 1 NC_016775.1 catalyzes the formation of glutamate from glutamine; glutaminase 322057 11686480 BSVBI22_B0336 Brucella suis VBI22 glutaminase YP_005108349.1 321104 D 1112912 CDS YP_005108350.1 376278317 11686481 322205..322549 1 NC_016775.1 inactive form; acid-resistance protein 322549 hdeA 11686481 hdeA Brucella suis VBI22 acid-resistance protein YP_005108350.1 322205 D 1112912 CDS YP_005108351.1 376278318 11686482 322712..322810 1 NC_016775.1 hypothetical protein 322810 11686482 BSVBI22_B0338 Brucella suis VBI22 hypothetical protein YP_005108351.1 322712 D 1112912 CDS YP_005108352.1 376278319 11686483 323062..323313 1 NC_016775.1 hypothetical protein 323313 11686483 BSVBI22_B0339 Brucella suis VBI22 hypothetical protein YP_005108352.1 323062 D 1112912 CDS YP_005108353.1 376278320 11686484 complement(323390..324982) 1 NC_016775.1 similar to SP:P77473; identified by sequence similarity; putative; EAL domain-containing protein 324982 11686484 BSVBI22_B0340 Brucella suis VBI22 EAL domain-containing protein YP_005108353.1 323390 R 1112912 CDS YP_005108354.1 376278321 11686485 complement(325277..325543) 1 NC_016775.1 hypothetical protein 325543 11686485 BSVBI22_B0341 Brucella suis VBI22 hypothetical protein YP_005108354.1 325277 R 1112912 CDS YP_005108355.1 376278322 11686486 325772..326659 1 NC_016775.1 identified by match to PFAM protein family HMM PF03466; LysR family transcriptional regulator 326659 11686486 BSVBI22_B0342 Brucella suis VBI22 LysR family transcriptional regulator YP_005108355.1 325772 D 1112912 CDS YP_005108356.1 376278323 11686487 complement(326780..328195) 1 NC_016775.1 similar to GP:3510759; identified by sequence similarity; putative; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 328195 11686487 BSVBI22_B0343 Brucella suis VBI22 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_005108356.1 326780 R 1112912 CDS YP_005108357.1 376278324 11686488 complement(328192..329625) 1 NC_016775.1 similar to GP:2738951, SP:P06187, GB:K03551, GB:X52093, PID:154137, and PID:47739; identified by sequence similarity; putative; phosphoglucomutase, putative 329625 11686488 BSVBI22_B0344 Brucella suis VBI22 phosphoglucomutase, putative YP_005108357.1 328192 R 1112912 CDS YP_005108358.1 376278325 11686489 complement(329745..330851) 1 NC_016775.1 similar to GP:7799513, and GP:7799513; identified by sequence similarity; putative; hypothetical protein 330851 11686489 BSVBI22_B0345 Brucella suis VBI22 hypothetical protein YP_005108358.1 329745 R 1112912 CDS YP_005108359.1 376278326 11686490 complement(330875..332230) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03595; voltage gated chloride channel family protein 332230 11686490 BSVBI22_B0346 Brucella suis VBI22 voltage gated chloride channel family protein YP_005108359.1 330875 R 1112912 CDS YP_005108360.1 376278327 11686491 complement(332289..332450) 1 NC_016775.1 hypothetical protein 332450 11686491 BSVBI22_B0347 Brucella suis VBI22 hypothetical protein YP_005108360.1 332289 R 1112912 CDS YP_005108361.1 376278328 11686492 332425..333918 1 NC_016775.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 333918 guaB 11686492 guaB Brucella suis VBI22 inosine 5'-monophosphate dehydrogenase YP_005108361.1 332425 D 1112912 CDS YP_005108362.1 376278329 11686493 complement(334123..335196) 1 NC_016775.1 similar to GP:15140396; identified by sequence similarity; putative; cytochrome c family protein 335196 11686493 BSVBI22_B0349 Brucella suis VBI22 cytochrome c family protein YP_005108362.1 334123 R 1112912 CDS YP_005108363.1 376278330 11686494 complement(335265..336218) 1 NC_016775.1 similar to GP:4098965, and GP:4098965; identified by sequence similarity; putative; transcriptional regulator OxyR 336218 oxyR 11686494 oxyR Brucella suis VBI22 transcriptional regulator OxyR YP_005108363.1 335265 R 1112912 CDS YP_005108364.1 376278331 11686495 336388..337887 1 NC_016775.1 similar to SP:Q59170, GB:L08666, SP:P45880, PID:190200, and PID:190201; identified by sequence similarity; putative; catalase 337887 katA 11686495 katA Brucella suis VBI22 catalase YP_005108364.1 336388 D 1112912 CDS YP_005108365.1 376278332 11686496 337982..338191 1 NC_016775.1 similar to GP:9082308; identified by sequence similarity; putative; hypothetical protein 338191 11686496 BSVBI22_B0352 Brucella suis VBI22 hypothetical protein YP_005108365.1 337982 D 1112912 CDS YP_005108366.1 376278333 11686497 338220..338846 1 NC_016775.1 identified by match to PFAM protein family HMM PF02600; disulfide bond formation protein DsbB, putative 338846 11686497 BSVBI22_B0353 Brucella suis VBI22 disulfide bond formation protein DsbB, putative YP_005108366.1 338220 D 1112912 CDS YP_005108367.1 376278334 11686498 339023..340312 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00563; sun protein, putative 340312 11686498 BSVBI22_B0354 Brucella suis VBI22 sun protein, putative YP_005108367.1 339023 D 1112912 CDS YP_005108368.1 376278335 11686499 340603..341058 1 NC_016775.1 identified by match to PFAM protein family HMM PF02584; hypothetical protein 341058 11686499 BSVBI22_B0355 Brucella suis VBI22 hypothetical protein YP_005108368.1 340603 D 1112912 CDS YP_005108369.1 376278336 11686500 341055..341687 1 NC_016775.1 Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 341687 11686500 BSVBI22_B0356 Brucella suis VBI22 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_005108369.1 341055 D 1112912 CDS YP_005108370.1 376278337 11686501 341796..343358 1 NC_016775.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 343358 guaA 11686501 guaA Brucella suis VBI22 GMP synthase YP_005108370.1 341796 D 1112912 CDS YP_005108371.1 376278338 11686502 343667..344875 1 NC_016775.1 identified by match to PFAM protein family HMM PF00589; phage integrase family site specific recombinase 344875 11686502 BSVBI22_B0358 Brucella suis VBI22 phage integrase family site specific recombinase YP_005108371.1 343667 D 1112912 CDS YP_005108372.1 376278339 11686503 345160..345390 1 NC_016775.1 similar to SP:P37447, GB:X76902, and PID:436890; identified by sequence similarity; putative; DNA-binding protein, putative 345390 11686503 BSVBI22_B0359 Brucella suis VBI22 DNA-binding protein, putative YP_005108372.1 345160 D 1112912 CDS YP_005108373.1 376278340 11686504 345471..346529 1 NC_016775.1 similar to GP:8117186, and GP:8117186; identified by sequence similarity; putative; repA-related protein 346529 11686504 BSVBI22_B0360 Brucella suis VBI22 repA-related protein YP_005108373.1 345471 D 1112912 CDS YP_005108374.1 376278341 11686505 complement(347578..347904) 1 NC_016775.1 hypothetical protein 347904 11686505 BSVBI22_B0361 Brucella suis VBI22 hypothetical protein YP_005108374.1 347578 R 1112912 CDS YP_005108375.1 376278342 11686506 complement(347907..349550) 1 NC_016775.1 similar to GB:X72841, SP:P31149, SP:Q09028, SP:Q16576, PID:1016273, and PID:297904; identified by sequence similarity; putative; trbL protein 349550 11686506 BSVBI22_B0362 Brucella suis VBI22 trbL protein YP_005108375.1 347907 R 1112912 CDS YP_005108376.1 376278343 11686507 complement(349553..349735) 1 NC_016775.1 hypothetical protein 349735 11686507 BSVBI22_B0363 Brucella suis VBI22 hypothetical protein YP_005108376.1 349553 R 1112912 CDS YP_005108377.1 376278344 11686508 complement(349738..350529) 1 NC_016775.1 similar to SP:P03833, GB:X01007, GB:X13109, GB:X16345, GB:Y00525, PID:43821, SP:P03833, GB:X01007, GB:X13109, GB:X16345, GB:Y00525, and PID:43821; identified by sequence similarity; putative; trbJ protein 350529 11686508 BSVBI22_B0364 Brucella suis VBI22 trbJ protein YP_005108377.1 349738 R 1112912 CDS YP_005108378.1 376278345 11686509 350627..350779 1 NC_016775.1 hypothetical protein 350779 11686509 BSVBI22_B0365 Brucella suis VBI22 hypothetical protein YP_005108378.1 350627 D 1112912 CDS YP_005108379.1 376278346 11686510 complement(350797..351021) 1 NC_016775.1 hypothetical protein 351021 11686510 BSVBI22_B0366 Brucella suis VBI22 hypothetical protein YP_005108379.1 350797 R 1112912 CDS YP_005108380.1 376278347 11686511 complement(351024..351242) 1 NC_016775.1 similar to GP:14523605, GB:L33243, GB:L43601, GB:L43602, GB:L43604, GB:L43605, GB:L43610, GB:L43617, GB:L43618, SP:P98161, PID:799335, PID:903758, and PID:904223; identified by sequence similarity; putative; traC protein 351242 11686511 BSVBI22_B0367 Brucella suis VBI22 traC protein YP_005108380.1 351024 R 1112912 CDS YP_005108381.1 376278348 11686512 351912..352292 1 NC_016775.1 similar to SP:P17909; identified by sequence similarity; putative; traJ protein 352292 11686512 BSVBI22_B0368 Brucella suis VBI22 traJ protein YP_005108381.1 351912 D 1112912 CDS YP_005108382.1 376278349 11686513 352289..354241 1 NC_016775.1 similar to GB:X62949, GB:L35249, SP:P15313, SP:P21281, PID:179563, PID:37794, PID:522193, PID:587442, GB:X62949, GB:L35249, SP:P15313, SP:P21281, PID:179563, PID:37794, PID:522193, and PID:587442; identified by sequence similarity; putative; traI protein, putative 354241 11686513 BSVBI22_B0369 Brucella suis VBI22 traI protein, putative YP_005108382.1 352289 D 1112912 CDS YP_005108383.1 376278350 11686514 complement(354648..356072) 1 NC_016775.1 hypothetical protein 356072 11686514 BSVBI22_B0370 Brucella suis VBI22 hypothetical protein YP_005108383.1 354648 R 1112912 CDS YP_005108384.1 376278351 11686515 complement(356226..357251) 1 NC_016775.1 hypothetical protein 357251 11686515 BSVBI22_B0371 Brucella suis VBI22 hypothetical protein YP_005108384.1 356226 R 1112912 CDS YP_005108385.1 376278352 11686516 complement(357285..358010) 1 NC_016775.1 hypothetical protein 358010 11686516 BSVBI22_B0372 Brucella suis VBI22 hypothetical protein YP_005108385.1 357285 R 1112912 CDS YP_005108386.1 376278353 11686517 complement(358189..359910) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00634; hypothetical protein 359910 11686517 BSVBI22_B0373 Brucella suis VBI22 hypothetical protein YP_005108386.1 358189 R 1112912 CDS YP_005108387.1 376278354 11686518 complement(360152..360976) 1 NC_016775.1 hypothetical protein 360976 11686518 BSVBI22_B0374 Brucella suis VBI22 hypothetical protein YP_005108387.1 360152 R 1112912 CDS YP_005108388.1 376278355 11686519 complement(361121..361315) 1 NC_016775.1 similar to GB:M23326, GB:X15261, GB:X13954, PID:1049195, PID:2358067, PID:312412, PID:37046, PID:37048, PID:37298, PID:37324, and PID:540457; identified by sequence similarity; putative; DNA-damage-inducible protein J, putative 361315 11686519 BSVBI22_B0375 Brucella suis VBI22 DNA-damage-inducible protein J, putative YP_005108388.1 361121 R 1112912 CDS YP_005108389.1 376278356 11686520 361725..361910 1 NC_016775.1 hypothetical protein 361910 11686520 BSVBI22_B0376 Brucella suis VBI22 hypothetical protein YP_005108389.1 361725 D 1112912 CDS YP_005108390.1 376278357 11686521 362022..362570 1 NC_016775.1 similar to GB:D14695, and PID:285961; identified by sequence similarity; putative; membrane antigen, putative 362570 11686521 BSVBI22_B0377 Brucella suis VBI22 membrane antigen, putative YP_005108390.1 362022 D 1112912 CDS YP_005108391.1 376278358 11686522 362574..362972 1 NC_016775.1 similar to GB:M20730, SP:P16534, GB:M24197, PID:150496, and PID:150515; identified by sequence similarity; putative; hypothetical protein 362972 11686522 BSVBI22_B0378 Brucella suis VBI22 hypothetical protein YP_005108391.1 362574 D 1112912 CDS YP_005108392.1 376278359 11686523 362979..363815 1 NC_016775.1 similar to GP:6469262, and GP:6469262; identified by sequence similarity; putative; FTR1 family iron permease 363815 11686523 BSVBI22_B0379 Brucella suis VBI22 FTR1 family iron permease YP_005108392.1 362979 D 1112912 CDS YP_005108393.1 376278360 11686524 363776..365209 1 NC_016775.1 similar to SP:P35097, and GB:Z47792; identified by sequence similarity; putative; hypothetical protein 365209 11686524 BSVBI22_B0380 Brucella suis VBI22 hypothetical protein YP_005108393.1 363776 D 1112912 CDS YP_005108394.1 376278361 11686525 complement(365467..367836) 1 NC_016775.1 similar to SP:Q9AEM9; identified by sequence similarity; putative; putative phosphoketolase 367836 xfp 11686525 xfp Brucella suis VBI22 putative phosphoketolase YP_005108394.1 365467 R 1112912 CDS YP_005108395.1 376278362 11686526 complement(367866..369071) 1 NC_016775.1 Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; acetate kinase 369071 11686526 BSVBI22_B0382 Brucella suis VBI22 acetate kinase YP_005108395.1 367866 R 1112912 CDS YP_005108396.1 376278363 11686527 369310..369471 1 NC_016775.1 hypothetical protein 369471 11686527 BSVBI22_B0383 Brucella suis VBI22 hypothetical protein YP_005108396.1 369310 D 1112912 CDS YP_005108397.1 376278364 11686528 369514..370677 1 NC_016775.1 identified by match to PFAM protein family HMM PF00067; heme-thiolate monooxygenase, putative 370677 11686528 BSVBI22_B0384 Brucella suis VBI22 heme-thiolate monooxygenase, putative YP_005108397.1 369514 D 1112912 CDS YP_005108398.1 376278365 11686529 complement(370748..371425) 1 NC_016775.1 similar to GP:14524114; identified by sequence similarity; putative; GntR family transcriptional regulator 371425 11686529 BSVBI22_B0385 Brucella suis VBI22 GntR family transcriptional regulator YP_005108398.1 370748 R 1112912 CDS YP_005108399.1 376278366 11686530 371483..371704 1 NC_016775.1 hypothetical protein 371704 11686530 BSVBI22_B0386 Brucella suis VBI22 hypothetical protein YP_005108399.1 371483 D 1112912 CDS YP_005108400.1 376278367 11686531 371697..372704 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00692; alcohol dehydrogenase, zinc-containing 372704 11686531 BSVBI22_B0387 Brucella suis VBI22 alcohol dehydrogenase, zinc-containing YP_005108400.1 371697 D 1112912 CDS YP_005108401.1 376278368 11686532 372788..373999 1 NC_016775.1 similar to SP:P04816, GB:L19201, SP:P32174, PID:304996, GB:U00096, and PID:1790325; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative 373999 11686532 BSVBI22_B0388 Brucella suis VBI22 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative YP_005108401.1 372788 D 1112912 CDS YP_005108402.1 376278369 11686533 374048..374932 1 NC_016775.1 similar to GP:19715091; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, permease protein 374932 11686533 BSVBI22_B0389 Brucella suis VBI22 branched-chain amino acid ABC transporter, permease protein YP_005108402.1 374048 D 1112912 CDS YP_005108403.1 376278370 11686535 376766..377470 1 NC_016775.1 similar to SP:P22731; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, ATP-binding protein 377470 11686535 BSVBI22_B0391 Brucella suis VBI22 branched-chain amino acid ABC transporter, ATP-binding protein YP_005108403.1 376766 D 1112912 CDS YP_005108404.1 376278371 11686536 377473..378270 1 NC_016775.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 378270 fabG 11686536 fabG Brucella suis VBI22 3-ketoacyl-(acyl-carrier-protein) reductase YP_005108404.1 377473 D 1112912 CDS YP_005108405.1 376278372 11686537 378275..379093 1 NC_016775.1 identified by match to PFAM protein family HMM PF00745; shikimate dehydrogenase family protein 379093 11686537 BSVBI22_B0393 Brucella suis VBI22 shikimate dehydrogenase family protein YP_005108405.1 378275 D 1112912 CDS YP_005108406.1 376278373 11686538 379098..380732 1 NC_016775.1 identified by match to PFAM protein family HMM PF00070; GMC family oxidoreductase 380732 11686538 BSVBI22_B0394 Brucella suis VBI22 GMC family oxidoreductase YP_005108406.1 379098 D 1112912 CDS YP_005108407.1 376278374 11686539 380757..382187 1 NC_016775.1 similar to GP:15159844; identified by sequence similarity; putative; aldehyde dehydrogenase family protein 382187 11686539 BSVBI22_B0395 Brucella suis VBI22 aldehyde dehydrogenase family protein YP_005108407.1 380757 D 1112912 CDS YP_005108408.1 376278375 11686540 382279..383442 1 NC_016775.1 similar to SP:P02917, GB:L19201, SP:P32174, PID:304996, GB:U00096, and PID:1790325; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative 383442 11686540 BSVBI22_B0396 Brucella suis VBI22 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative YP_005108408.1 382279 D 1112912 CDS YP_005108409.1 376278376 11686541 383505..384632 1 NC_016775.1 similar to GP:15075876; identified by sequence similarity; putative; alcohol dehydrogenase, zinc-containing 384632 11686541 BSVBI22_B0397 Brucella suis VBI22 alcohol dehydrogenase, zinc-containing YP_005108409.1 383505 D 1112912 CDS YP_005108410.1 376278377 11686542 384837..385832 1 NC_016775.1 similar to SP:P49307; identified by sequence similarity; putative; oxidoreductase, putative 385832 11686542 BSVBI22_B0398 Brucella suis VBI22 oxidoreductase, putative YP_005108410.1 384837 D 1112912 CDS YP_005108411.1 376278378 11686543 385820..387106 1 NC_016775.1 identified by match to PFAM protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase 387106 11686543 BSVBI22_B0399 Brucella suis VBI22 Gfo/Idh/MocA family oxidoreductase YP_005108411.1 385820 D 1112912 CDS YP_005108412.1 376278379 11686544 complement(386884..387837) 1 NC_016775.1 similar to SP:P24137, GB:M88627, SP:P43334, and PID:476741; identified by sequence similarity; putative; peptide ABC transporter, ATP-binding protein 387837 11686544 BSVBI22_B0400 Brucella suis VBI22 peptide ABC transporter, ATP-binding protein YP_005108412.1 386884 R 1112912 CDS YP_005108413.1 376278380 11686545 complement(387834..388850) 1 NC_016775.1 similar to GB:M88627, SP:P43334, and PID:476741; identified by sequence similarity; putative; peptide ABC transporter, ATP-binding protein 388850 11686545 BSVBI22_B0401 Brucella suis VBI22 peptide ABC transporter, ATP-binding protein YP_005108413.1 387834 R 1112912 CDS YP_005108414.1 376278381 11686546 complement(388861..389778) 1 NC_016775.1 similar to GP:12541464; identified by sequence similarity; putative; dihydrodipicolinate synthase family protein 389778 11686546 BSVBI22_B0402 Brucella suis VBI22 dihydrodipicolinate synthase family protein YP_005108414.1 388861 R 1112912 CDS YP_005108415.1 376278382 11686547 complement(389798..390706) 1 NC_016775.1 similar to GP:15160372; identified by sequence similarity; putative; peptide ABC transporter, permease protein 390706 11686547 BSVBI22_B0403 Brucella suis VBI22 peptide ABC transporter, permease protein YP_005108415.1 389798 R 1112912 CDS YP_005108416.1 376278383 11686548 complement(390672..391631) 1 NC_016775.1 similar to GB:X07820, SP:P09238, and PID:36629; identified by sequence similarity; putative; peptide ABC transporter, permease protein 391631 11686548 BSVBI22_B0404 Brucella suis VBI22 peptide ABC transporter, permease protein YP_005108416.1 390672 R 1112912 CDS YP_005108417.1 376278384 11686549 complement(391731..393314) 1 NC_016775.1 similar to GP:15158790, and GP:6969001; identified by sequence similarity; putative; peptide ABC transporter, periplasmic peptide-binding protein 393314 11686549 BSVBI22_B0405 Brucella suis VBI22 peptide ABC transporter, periplasmic peptide-binding protein YP_005108417.1 391731 R 1112912 CDS YP_005108418.1 376278385 11686550 complement(393311..394039) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 394039 11686550 BSVBI22_B0406 Brucella suis VBI22 GntR family transcriptional regulator YP_005108418.1 393311 R 1112912 CDS YP_005108419.1 376278386 11686551 394199..395776 1 NC_016775.1 identified by match to PFAM protein family HMM PF00218; ROK family protein 395776 11686551 BSVBI22_B0407 Brucella suis VBI22 ROK family protein YP_005108419.1 394199 D 1112912 CDS YP_005108420.1 376278387 11686553 397066..397341 1 NC_016775.1 hypothetical protein 397341 11686553 BSVBI22_B0409 Brucella suis VBI22 hypothetical protein YP_005108420.1 397066 D 1112912 CDS YP_005108421.1 376278388 11686554 complement(397342..398100) 1 NC_016775.1 similar to GP:5478244, and GP:5478244; identified by sequence similarity; putative; Crp/FNR family transcriptional regulator 398100 11686554 BSVBI22_B0410 Brucella suis VBI22 Crp/FNR family transcriptional regulator YP_005108421.1 397342 R 1112912 CDS YP_005108422.1 376278389 11686555 398463..399230 1 NC_016775.1 similar to GP:5478243, and GP:5478243; identified by sequence similarity; putative; LuxR family transcriptional regulator 399230 11686555 BSVBI22_B0411 Brucella suis VBI22 LuxR family transcriptional regulator YP_005108422.1 398463 D 1112912 CDS YP_005108423.1 376278390 11686556 399267..401456 1 NC_016775.1 similar to GP:5478242, and GP:5478242; identified by sequence similarity; putative; exopolysaccharide biosynthesis protein Bme12 401456 11686556 BSVBI22_B0412 Brucella suis VBI22 exopolysaccharide biosynthesis protein Bme12 YP_005108423.1 399267 D 1112912 CDS YP_005108424.1 376278391 11686557 401466..402713 1 NC_016775.1 similar to GP:5478241, GP:5478241, GB:M83667, SP:P49716, and PID:189176; identified by sequence similarity; putative; exopolysaccharide biosynthesis protein Bme11 402713 11686557 BSVBI22_B0413 Brucella suis VBI22 exopolysaccharide biosynthesis protein Bme11 YP_005108424.1 401466 D 1112912 CDS YP_005108425.1 376278392 11686558 complement(402818..403798) 1 NC_016775.1 similar to GP:5478240; identified by sequence similarity; putative; fucose synthetase family protein 403798 11686558 BSVBI22_B0414 Brucella suis VBI22 fucose synthetase family protein YP_005108425.1 402818 R 1112912 CDS YP_005108426.1 376278393 11686559 complement(403782..404852) 1 NC_016775.1 similar to GP:5478239, and SP:P15527; identified by sequence similarity; putative; GDP-mannose 4,6-dehydratase Bme9 404852 11686559 BSVBI22_B0415 Brucella suis VBI22 GDP-mannose 4,6-dehydratase Bme9 YP_005108426.1 403782 R 1112912 CDS YP_005108427.1 376278394 11686561 406387..407622 1 NC_016775.1 similar to GP:5478237, and GP:5478237; identified by sequence similarity; putative; glycosyl transferase, group 1 family protein 407622 11686561 BSVBI22_B0417 Brucella suis VBI22 glycosyl transferase, group 1 family protein YP_005108427.1 406387 D 1112912 CDS YP_005108428.1 376278395 11686562 407619..408815 1 NC_016775.1 similar to GP:5478236, and GP:5478236; identified by sequence similarity; putative; glycosyl transferase, group 1 family protein 408815 11686562 BSVBI22_B0418 Brucella suis VBI22 glycosyl transferase, group 1 family protein YP_005108428.1 407619 D 1112912 CDS YP_005108429.1 376278396 11686563 complement(408886..409608) 1 NC_016775.1 similar to GB:X70959, SP:P42459, PID:452384, GB:X70959, SP:P42459, and PID:452384; identified by sequence similarity; putative; outer membrane protein, 31 kDa 409608 omp31-2 11686563 omp31-2 Brucella suis VBI22 outer membrane protein, 31 kDa YP_005108429.1 408886 R 1112912 CDS YP_005108430.1 376278397 11686564 complement(410005..410619) 1 NC_016775.1 similar to GP:5478235; identified by sequence similarity; putative; acetyltransferase 410619 11686564 BSVBI22_B0420 Brucella suis VBI22 acetyltransferase YP_005108430.1 410005 R 1112912 CDS YP_005108431.1 376278398 11686566 complement(411890..412507) 1 NC_016775.1 similar to GP:5478233, and GP:5478233; identified by sequence similarity; putative; Bme2 protein 412507 11686566 BSVBI22_B0422 Brucella suis VBI22 Bme2 protein YP_005108431.1 411890 R 1112912 CDS YP_005108432.1 376278399 11686567 complement(412504..413385) 1 NC_016775.1 similar to GP:5478232; identified by sequence similarity; putative; glycosyl transferase, group 2 family protein 413385 11686567 BSVBI22_B0423 Brucella suis VBI22 glycosyl transferase, group 2 family protein YP_005108432.1 412504 R 1112912 CDS YP_005108433.1 376278400 11686568 complement(413382..414509) 1 NC_016775.1 similar to GP:15158359, GB:J00109, GB:K03512, GB:M28637, GB:A15601, GB:K03513, GB:A11954, GB:X15943, SP:P01258, SP:P06881, PID:1340176, PID:179799, PID:179828, PID:180466, PID:296638, and PID:457134; identified by sequence similarity; putative; undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase, putative 414509 11686568 BSVBI22_B0424 Brucella suis VBI22 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase, putative YP_005108433.1 413382 R 1112912 CDS YP_005108434.1 376278401 11686569 414802..416295 1 NC_016775.1 similar to GP:15158365; identified by sequence similarity; putative; polysaccharide biosynthesis protein 416295 11686569 BSVBI22_B0425 Brucella suis VBI22 polysaccharide biosynthesis protein YP_005108434.1 414802 D 1112912 CDS YP_005108435.1 376278402 11686570 416311..417324 1 NC_016775.1 similar to GP:15158366; identified by sequence similarity; putative; glycosyl transferase, group 2 family protein 417324 11686570 BSVBI22_B0426 Brucella suis VBI22 glycosyl transferase, group 2 family protein YP_005108435.1 416311 D 1112912 CDS YP_005108436.1 376278403 11686571 complement(417280..418521) 1 NC_016775.1 similar to GP:15158364, and GP:15158364; identified by sequence similarity; putative; hypothetical protein 418521 11686571 BSVBI22_B0427 Brucella suis VBI22 hypothetical protein YP_005108436.1 417280 R 1112912 CDS YP_005108437.1 376278404 11686572 418638..420017 1 NC_016775.1 similar to GP:15158361; identified by sequence similarity; putative; glycosyl transferase, group 1 family protein 420017 11686572 BSVBI22_B0428 Brucella suis VBI22 glycosyl transferase, group 1 family protein YP_005108437.1 418638 D 1112912 CDS YP_005108438.1 376278405 11686573 420055..421416 1 NC_016775.1 catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; glutamate-1-semialdehyde 2,1-aminomutase 421416 11686573 BSVBI22_B0429 Brucella suis VBI22 glutamate-1-semialdehyde 2,1-aminomutase YP_005108438.1 420055 D 1112912 CDS YP_005108439.1 376278406 11686574 421395..422729 1 NC_016775.1 similar to GP:15158360, and GP:15158360; identified by sequence similarity; putative; hypothetical protein 422729 11686574 BSVBI22_B0430 Brucella suis VBI22 hypothetical protein YP_005108439.1 421395 D 1112912 CDS YP_005108440.1 376278407 11686575 422850..423911 1 NC_016775.1 similar to GP:15158370; identified by sequence similarity; putative; epimerase/dehydratase family protein, putative 423911 11686575 BSVBI22_B0431 Brucella suis VBI22 epimerase/dehydratase family protein, putative YP_005108440.1 422850 D 1112912 CDS YP_005108441.1 376278408 11686576 423911..425263 1 NC_016775.1 similar to GP:15158371, and GP:15158371; identified by sequence similarity; putative; hypothetical protein 425263 11686576 BSVBI22_B0432 Brucella suis VBI22 hypothetical protein YP_005108441.1 423911 D 1112912 CDS YP_005108442.1 376278409 11686577 complement(425226..425750) 1 NC_016775.1 similar to SP:P29202, and PID:148782; identified by sequence similarity; putative; dTDP-4-dehydrorhamnose 3,5-epimerase 425750 rfbC 11686577 rfbC Brucella suis VBI22 dTDP-4-dehydrorhamnose 3,5-epimerase YP_005108442.1 425226 R 1112912 CDS YP_005108443.1 376278410 11686578 426071..427372 1 NC_016775.1 similar to GP:15158375; identified by sequence similarity; putative; methyltransferase, putative 427372 11686578 BSVBI22_B0434 Brucella suis VBI22 methyltransferase, putative YP_005108443.1 426071 D 1112912 CDS YP_005108444.1 376278411 11686579 427375..428184 1 NC_016775.1 similar to GP:15158376; identified by sequence similarity; putative; nucleotidyltransferase family protein 428184 11686579 BSVBI22_B0435 Brucella suis VBI22 nucleotidyltransferase family protein YP_005108444.1 427375 D 1112912 CDS YP_005108445.1 376278412 11686580 428181..428837 1 NC_016775.1 similar to GP:15158377, and GP:6066675; identified by sequence similarity; putative; hypothetical protein 428837 11686580 BSVBI22_B0436 Brucella suis VBI22 hypothetical protein YP_005108445.1 428181 D 1112912 CDS YP_005108446.1 376278413 11686581 428905..429036 1 NC_016775.1 hypothetical protein 429036 11686581 BSVBI22_B0437 Brucella suis VBI22 hypothetical protein YP_005108446.1 428905 D 1112912 CDS YP_005108447.1 376278414 11686582 complement(429033..430313) 1 NC_016775.1 similar to GP:15160336; identified by sequence similarity; putative; uracil-xanthine permease 430313 11686582 BSVBI22_B0438 Brucella suis VBI22 uracil-xanthine permease YP_005108447.1 429033 R 1112912 CDS YP_005108448.1 376278415 11686583 complement(430430..431926) 1 NC_016775.1 similar to SP:O66131; identified by sequence similarity; putative; glycerol kinase 431926 glpK 11686583 glpK Brucella suis VBI22 glycerol kinase YP_005108448.1 430430 R 1112912 CDS YP_005108449.1 376278416 11686584 complement(432053..433354) 1 NC_016775.1 identified by match to PFAM protein family HMM PF04024; major facilitator family transporter 433354 11686584 BSVBI22_B0440 Brucella suis VBI22 major facilitator family transporter YP_005108449.1 432053 R 1112912 CDS YP_005108450.1 376278417 11686585 433459..434346 1 NC_016775.1 similar to GP:4106617; identified by sequence similarity; putative; LysR family transcriptional regulator 434346 11686585 BSVBI22_B0441 Brucella suis VBI22 LysR family transcriptional regulator YP_005108450.1 433459 D 1112912 CDS YP_005108451.1 376278418 11686586 434431..434871 1 NC_016775.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 434871 11686586 BSVBI22_B0442 Brucella suis VBI22 methionine sulfoxide reductase B YP_005108451.1 434431 D 1112912 CDS YP_005108452.1 376278419 11686587 complement(434872..435999) 1 NC_016775.1 similar to GP:15159873, and SP:P45857; identified by sequence similarity; putative; acyl-CoA dehydrogenase 435999 11686587 BSVBI22_B0443 Brucella suis VBI22 acyl-CoA dehydrogenase YP_005108452.1 434872 R 1112912 CDS YP_005108453.1 376278420 11686588 complement(435999..437189) 1 NC_016775.1 similar to GB:X03342, SP:P02433, and PID:36132; identified by sequence similarity; putative; acetyl-CoA acetyltransferase 437189 phbA-2 11686588 phbA-2 Brucella suis VBI22 acetyl-CoA acetyltransferase YP_005108453.1 435999 R 1112912 CDS YP_005108454.1 376278421 11686589 complement(437258..438025) 1 NC_016775.1 similar to GP:9948613, GB:M29297, and SP:P20189; identified by sequence similarity; putative; 3-hydroxyacyl-CoA dehydrogenase, putative 438025 11686589 BSVBI22_B0445 Brucella suis VBI22 3-hydroxyacyl-CoA dehydrogenase, putative YP_005108454.1 437258 R 1112912 CDS YP_005108455.1 376278422 11686590 complement(438038..439708) 1 NC_016775.1 similar to GB:M25667, GB:S66533, GB:S66534, GB:S66541, SP:P17677, and PID:182970; identified by sequence similarity; putative; acetyl-CoA synthetase, putative 439708 11686590 BSVBI22_B0446 Brucella suis VBI22 acetyl-CoA synthetase, putative YP_005108455.1 438038 R 1112912 CDS YP_005108456.1 376278423 11686591 439835..440818 1 NC_016775.1 similar to GP:14523919; identified by sequence similarity; putative; AraC family transcriptional regulator 440818 11686591 BSVBI22_B0447 Brucella suis VBI22 AraC family transcriptional regulator YP_005108456.1 439835 D 1112912 CDS YP_005108457.1 376278424 11686592 440866..441045 1 NC_016775.1 hypothetical protein 441045 11686592 BSVBI22_B0448 Brucella suis VBI22 hypothetical protein YP_005108457.1 440866 D 1112912 CDS YP_005108458.1 376278425 11686593 441042..442280 1 NC_016775.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 442280 serA-2 11686593 serA-2 Brucella suis VBI22 D-3-phosphoglycerate dehydrogenase YP_005108458.1 441042 D 1112912 CDS YP_005108459.1 376278426 11686594 complement(442333..442827) 1 NC_016775.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 442827 def 11686594 def Brucella suis VBI22 peptide deformylase YP_005108459.1 442333 R 1112912 CDS YP_005108460.1 376278427 11686595 complement(443573..444514) 1 NC_016775.1 similar to GB:Z29635, SP:P46374, PID:455002, GB:Z29635, SP:P46374, and PID:455002; identified by sequence similarity; putative; hypothetical protein 444514 11686595 BSVBI22_B0451 Brucella suis VBI22 hypothetical protein YP_005108460.1 443573 R 1112912 CDS YP_005108461.1 376278428 11686596 444827..445150 1 NC_016775.1 identified by match to PFAM protein family HMM PF01022; ArsR family transcriptional regulator 445150 11686596 BSVBI22_B0452 Brucella suis VBI22 ArsR family transcriptional regulator YP_005108461.1 444827 D 1112912 CDS YP_005108462.1 376278429 11686597 445150..445557 1 NC_016775.1 similar to GP:14523677, and GP:14523677; identified by sequence similarity; putative; hypothetical protein 445557 11686597 BSVBI22_B0453 Brucella suis VBI22 hypothetical protein YP_005108462.1 445150 D 1112912 CDS YP_005108463.1 376278430 11686598 445554..445991 1 NC_016775.1 hypothetical protein 445991 11686598 BSVBI22_B0454 Brucella suis VBI22 hypothetical protein YP_005108463.1 445554 D 1112912 CDS YP_005108464.1 376278431 11686599 complement(446014..446721) 1 NC_016775.1 similar to GP:14524042; identified by sequence similarity; putative; GntR family transcriptional regulator 446721 11686599 BSVBI22_B0455 Brucella suis VBI22 GntR family transcriptional regulator YP_005108464.1 446014 R 1112912 CDS YP_005108465.1 376278432 11686600 446967..448025 1 NC_016775.1 identified by match to PFAM protein family HMM PF01594; hypothetical protein 448025 11686600 BSVBI22_B0456 Brucella suis VBI22 hypothetical protein YP_005108465.1 446967 D 1112912 CDS YP_005108466.1 376278433 11686601 448153..448341 1 NC_016775.1 hypothetical protein 448341 11686601 BSVBI22_B0457 Brucella suis VBI22 hypothetical protein YP_005108466.1 448153 D 1112912 CDS YP_005108467.1 376278434 11686602 448644..449363 1 NC_016775.1 identified by match to PFAM protein family HMM PF03130; TetR family transcriptional regulator 449363 11686602 BSVBI22_B0458 Brucella suis VBI22 TetR family transcriptional regulator YP_005108467.1 448644 D 1112912 CDS YP_005108468.1 376278435 11686603 449368..450312 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00998; HlyD family secretion protein 450312 11686603 BSVBI22_B0459 Brucella suis VBI22 HlyD family secretion protein YP_005108468.1 449368 D 1112912 CDS YP_005108469.1 376278436 11686605 451233..452366 1 NC_016775.1 similar to GP:17427173; identified by sequence similarity; putative; ABC transporter, permease protein 452366 11686605 BSVBI22_B0461 Brucella suis VBI22 ABC transporter, permease protein YP_005108469.1 451233 D 1112912 CDS YP_005108470.1 376278437 11686606 452404..452802 1 NC_016775.1 similar to GP:15158870, and GP:15074195; identified by sequence similarity; putative; hypothetical protein 452802 11686606 BSVBI22_B0462 Brucella suis VBI22 hypothetical protein YP_005108470.1 452404 D 1112912 CDS YP_005108471.1 376278438 11686607 complement(452809..453627) 1 NC_016775.1 similar to GP:13021750, and SP:Q47539; identified by sequence similarity; putative; taurine ABC transporter, permease protein, putative 453627 11686607 BSVBI22_B0463 Brucella suis VBI22 taurine ABC transporter, permease protein, putative YP_005108471.1 452809 R 1112912 CDS YP_005108472.1 376278439 11686608 complement(453620..454387) 1 NC_016775.1 similar to SP:P37338, GB:U00096, and PID:1789018; identified by sequence similarity; putative; ABC transporter, ATP-binding protein 454387 11686608 BSVBI22_B0464 Brucella suis VBI22 ABC transporter, ATP-binding protein YP_005108472.1 453620 R 1112912 CDS YP_005108473.1 376278440 11686609 complement(454433..455455) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00497; ABC transporter, periplasmic substrate-binding protein 455455 11686609 BSVBI22_B0465 Brucella suis VBI22 ABC transporter, periplasmic substrate-binding protein YP_005108473.1 454433 R 1112912 CDS YP_005108474.1 376278441 11686611 456313..457944 1 NC_016775.1 similar to GP:15074065; identified by sequence similarity; putative; transporter, putative 457944 11686611 BSVBI22_B0467 Brucella suis VBI22 transporter, putative YP_005108474.1 456313 D 1112912 CDS YP_005108475.1 376278442 11686612 457969..459018 1 NC_016775.1 similar to GP:15156118; identified by sequence similarity; putative; HlyD family secretion protein 459018 11686612 BSVBI22_B0468 Brucella suis VBI22 HlyD family secretion protein YP_005108475.1 457969 D 1112912 CDS YP_005108476.1 376278443 11686613 complement(459090..460514) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01386; osmolarity sensor protein EnvZ, putative 460514 11686613 BSVBI22_B0469 Brucella suis VBI22 osmolarity sensor protein EnvZ, putative YP_005108476.1 459090 R 1112912 CDS YP_005108477.1 376278444 11686614 complement(460511..461227) 1 NC_016775.1 similar to GP:14023190; identified by sequence similarity; putative; transcriptional regulatory protein OmpR, putative 461227 11686614 BSVBI22_B0470 Brucella suis VBI22 transcriptional regulatory protein OmpR, putative YP_005108477.1 460511 R 1112912 CDS YP_005108478.1 376278445 11686615 complement(461421..461567) 1 NC_016775.1 hypothetical protein 461567 11686615 BSVBI22_B0471 Brucella suis VBI22 hypothetical protein YP_005108478.1 461421 R 1112912 CDS YP_005108479.1 376278446 11686616 461551..461916 1 NC_016775.1 hypothetical protein 461916 11686616 BSVBI22_B0472 Brucella suis VBI22 hypothetical protein YP_005108479.1 461551 D 1112912 CDS YP_005108480.1 376278447 11686617 461928..462080 1 NC_016775.1 hypothetical protein 462080 11686617 BSVBI22_B0473 Brucella suis VBI22 hypothetical protein YP_005108480.1 461928 D 1112912 CDS YP_005108481.1 376278448 11686618 462340..462690 1 NC_016775.1 similar to GP:14026911; identified by sequence similarity; putative; hypothetical protein 462690 11686618 BSVBI22_B0474 Brucella suis VBI22 hypothetical protein YP_005108481.1 462340 D 1112912 CDS YP_005108482.1 376278449 11686619 complement(462813..464087) 1 NC_016775.1 NADH dehydrogenase 464087 11686619 BSVBI22_B0475 Brucella suis VBI22 NADH dehydrogenase YP_005108482.1 462813 R 1112912 CDS YP_005108483.1 376278450 11686620 complement(464170..464619) 1 NC_016775.1 similar to GP:15155841; identified by sequence similarity; putative; MarR family transcriptional regulator 464619 11686620 BSVBI22_B0476 Brucella suis VBI22 MarR family transcriptional regulator YP_005108483.1 464170 R 1112912 CDS YP_005108484.1 376278451 11686621 464901..465680 1 NC_016775.1 similar to GP:15075862; identified by sequence similarity; putative; glyoxalase, putative 465680 11686621 BSVBI22_B0477 Brucella suis VBI22 glyoxalase, putative YP_005108484.1 464901 D 1112912 CDS YP_005108485.1 376278452 11686622 complement(465744..465914) 1 NC_016775.1 hypothetical protein 465914 11686622 BSVBI22_B0478 Brucella suis VBI22 hypothetical protein YP_005108485.1 465744 R 1112912 CDS YP_005108486.1 376278453 11686623 complement(465961..467394) 1 NC_016775.1 similar to GP:15074955; identified by sequence similarity; putative; amino acid carrier family protein 467394 11686623 BSVBI22_B0479 Brucella suis VBI22 amino acid carrier family protein YP_005108486.1 465961 R 1112912 CDS YP_005108487.1 376278454 11686624 467408..467665 1 NC_016775.1 hypothetical protein 467665 11686624 BSVBI22_B0480 Brucella suis VBI22 hypothetical protein YP_005108487.1 467408 D 1112912 CDS YP_005108488.1 376278455 11686625 467822..468742 1 NC_016775.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 468742 metA 11686625 metA Brucella suis VBI22 homoserine O-succinyltransferase YP_005108488.1 467822 D 1112912 CDS YP_005108489.1 376278456 11686626 complement(468810..469799) 1 NC_016775.1 similar to GP:15140555; identified by sequence similarity; putative; glucosyl hydrolase family protein 469799 11686626 BSVBI22_B0482 Brucella suis VBI22 glucosyl hydrolase family protein YP_005108489.1 468810 R 1112912 CDS YP_005108490.1 376278457 11686627 complement(470152..471132) 1 NC_016775.1 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 471132 11686627 BSVBI22_B0483 Brucella suis VBI22 3-oxoacyl-(acyl carrier protein) synthase II YP_005108490.1 470152 R 1112912 CDS YP_005108491.1 376278458 11686628 complement(471129..472403) 1 NC_016775.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase 472403 bioA 11686628 bioA Brucella suis VBI22 adenosylmethionine--8-amino-7-oxononanoate transaminase YP_005108491.1 471129 R 1112912 CDS YP_005108492.1 376278459 11686629 complement(472400..473038) 1 NC_016775.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 473038 bioD 11686629 bioD Brucella suis VBI22 dithiobiotin synthetase YP_005108492.1 472400 R 1112912 CDS YP_005108493.1 376278460 11686630 complement(473035..474171) 1 NC_016775.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 474171 bioF 11686630 bioF Brucella suis VBI22 8-amino-7-oxononanoate synthase YP_005108493.1 473035 R 1112912 CDS YP_005108494.1 376278461 11686631 complement(474168..475154) 1 NC_016775.1 similar to GB:L05091, GB:U58682, SP:P25112, PID:1518637, and PID:337403; identified by sequence similarity; putative; biotin synthase 475154 bioB 11686631 bioB Brucella suis VBI22 biotin synthase YP_005108494.1 474168 R 1112912 CDS YP_005108495.1 376278462 11686632 475426..475587 1 NC_016775.1 hypothetical protein 475587 11686632 BSVBI22_B0488 Brucella suis VBI22 hypothetical protein YP_005108495.1 475426 D 1112912 CDS YP_005108496.1 376278463 11686633 complement(475565..475846) 1 NC_016775.1 hypothetical protein 475846 11686633 BSVBI22_B0489 Brucella suis VBI22 hypothetical protein YP_005108496.1 475565 R 1112912 CDS YP_005108497.1 376278464 11686634 complement(475943..476056) 1 NC_016775.1 hypothetical protein 476056 11686634 BSVBI22_B0490 Brucella suis VBI22 hypothetical protein YP_005108497.1 475943 R 1112912 CDS YP_005108498.1 376278465 11686635 476109..476627 1 NC_016775.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein 476627 mogA 11686635 mogA Brucella suis VBI22 molybdenum cofactor biosynthesis protein YP_005108498.1 476109 D 1112912 CDS YP_005108499.1 376278466 11686636 complement(476679..477278) 1 NC_016775.1 hypothetical protein 477278 11686636 BSVBI22_B0492 Brucella suis VBI22 hypothetical protein YP_005108499.1 476679 R 1112912 CDS YP_005108500.1 376278467 11686637 477345..477464 1 NC_016775.1 hypothetical protein 477464 11686637 BSVBI22_B0493 Brucella suis VBI22 hypothetical protein YP_005108500.1 477345 D 1112912 CDS YP_005108501.1 376278468 11686638 477602..478930 1 NC_016775.1 identified by match to PFAM protein family HMM PF00070; hypothetical protein 478930 11686638 BSVBI22_B0494 Brucella suis VBI22 hypothetical protein YP_005108501.1 477602 D 1112912 CDS YP_005108502.1 376278469 11686639 479371..482289 1 NC_016775.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+; putative monovalent cation/H+ antiporter subunit A 482289 11686639 BSVBI22_B0495 Brucella suis VBI22 putative monovalent cation/H+ antiporter subunit A YP_005108502.1 479371 D 1112912 CDS YP_005108503.1 376278470 11686640 482289..482627 1 NC_016775.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C 482627 11686640 BSVBI22_B0496 Brucella suis VBI22 putative monovalent cation/H+ antiporter subunit C YP_005108503.1 482289 D 1112912 CDS YP_005108504.1 376278471 11686641 482630..484258 1 NC_016775.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 484258 11686641 BSVBI22_B0497 Brucella suis VBI22 putative monovalent cation/H+ antiporter subunit D YP_005108504.1 482630 D 1112912 CDS YP_005108505.1 376278472 11686642 484255..484770 1 NC_016775.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit E 484770 11686642 BSVBI22_B0498 Brucella suis VBI22 putative monovalent cation/H+ antiporter subunit E YP_005108505.1 484255 D 1112912 CDS YP_005108506.1 376278473 11686643 484767..485048 1 NC_016775.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit F 485048 phaF 11686643 phaF Brucella suis VBI22 putative monovalent cation/H+ antiporter subunit F YP_005108506.1 484767 D 1112912 CDS YP_005108507.1 376278474 11686644 485045..485407 1 NC_016775.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit G 485407 11686644 BSVBI22_B0500 Brucella suis VBI22 putative monovalent cation/H+ antiporter subunit G YP_005108507.1 485045 D 1112912 CDS YP_005108508.1 376278475 11686645 485424..485756 1 NC_016775.1 hypothetical protein 485756 11686645 BSVBI22_B0501 Brucella suis VBI22 hypothetical protein YP_005108508.1 485424 D 1112912 CDS YP_005108509.1 376278476 11686646 485832..486368 1 NC_016775.1 similar to GP:15159185, GB:Z27502, GB:Z29983, SP:P04438, PID:1335182, PID:32878, PID:474960, PID:505435, and PID:563647; identified by sequence similarity; putative; hypothetical protein 486368 11686646 BSVBI22_B0502 Brucella suis VBI22 hypothetical protein YP_005108509.1 485832 D 1112912 CDS YP_005108510.1 376278477 11686647 486476..488101 1 NC_016775.1 similar to GP:9858820, GB:M24400, SP:P17538, and PID:181190; identified by sequence similarity; putative; ABC transporter, ATP-binding protein CydD 488101 cydD 11686647 cydD Brucella suis VBI22 ABC transporter, ATP-binding protein CydD YP_005108510.1 486476 D 1112912 CDS YP_005108511.1 376278478 11686648 488098..489780 1 NC_016775.1 similar to GP:9858821; identified by sequence similarity; putative; ABC transporter, ATP-binding/permease protein 489780 11686648 BSVBI22_B0504 Brucella suis VBI22 ABC transporter, ATP-binding/permease protein YP_005108511.1 488098 D 1112912 CDS YP_005108512.1 376278479 11686649 489924..491501 1 NC_016775.1 similar to GP:9858822, and SP:P11026; identified by sequence similarity; putative; cytochrome d ubiquinol oxidase, subunit I 491501 cydA 11686649 cydA Brucella suis VBI22 cytochrome d ubiquinol oxidase, subunit I YP_005108512.1 489924 D 1112912 CDS YP_005108513.1 376278480 11686650 491507..492661 1 NC_016775.1 similar to GB:X59066, GB:X65460, GB:D28126, GB:D14710, SP:P25705, PID:28938, PID:34468, PID:559317, and PID:559325; identified by sequence similarity; putative; cytochrome d ubiquinol oxidase, subunit II 492661 cydB 11686650 cydB Brucella suis VBI22 cytochrome d ubiquinol oxidase, subunit II YP_005108513.1 491507 D 1112912 CDS YP_005108514.1 376278481 11686651 492639..492833 1 NC_016775.1 similar to SP:P30858, GB:X86160, PID:769790, GB:U00096, PID:1651397, and PID:1787089; identified by sequence similarity; putative; ybgT protein 492833 ybgT 11686651 ybgT Brucella suis VBI22 ybgT protein YP_005108514.1 492639 D 1112912 CDS YP_005108515.1 376278482 11686652 complement(492884..493657) 1 NC_016775.1 similar to GP:15073129; identified by sequence similarity; putative; GntR family transcriptional regulator 493657 11686652 BSVBI22_B0508 Brucella suis VBI22 GntR family transcriptional regulator YP_005108515.1 492884 R 1112912 CDS YP_005108516.1 376278483 11686653 complement(493654..494541) 1 NC_016775.1 similar to GP:15073128, and GP:15073128; identified by sequence similarity; putative; hypothetical protein 494541 11686653 BSVBI22_B0509 Brucella suis VBI22 hypothetical protein YP_005108516.1 493654 R 1112912 CDS YP_005108517.1 376278484 11686654 494705..494893 1 NC_016775.1 hypothetical protein 494893 11686654 BSVBI22_B0510 Brucella suis VBI22 hypothetical protein YP_005108517.1 494705 D 1112912 CDS YP_005108518.1 376278485 11686655 494890..496149 1 NC_016775.1 similar to GP:15073126, and SP:Q00749; identified by sequence similarity; putative; sugar ABC transporter, periplasmic sugar-binding protein 496149 11686655 BSVBI22_B0511 Brucella suis VBI22 sugar ABC transporter, periplasmic sugar-binding protein YP_005108518.1 494890 D 1112912 CDS YP_005108519.1 376278486 11686656 complement(496374..496502) 1 NC_016775.1 hypothetical protein 496502 11686656 BSVBI22_B0512 Brucella suis VBI22 hypothetical protein YP_005108519.1 496374 R 1112912 CDS YP_005108520.1 376278487 11686657 496522..497466 1 NC_016775.1 similar to GP:15073125, and SP:P29823; identified by sequence similarity; putative; sugar ABC transporter, permease protein 497466 11686657 BSVBI22_B0513 Brucella suis VBI22 sugar ABC transporter, permease protein YP_005108520.1 496522 D 1112912 CDS YP_005108521.1 376278488 11686658 497479..498318 1 NC_016775.1 similar to GP:15073124; identified by sequence similarity; putative; sugar ABC transporter, permease protein 498318 11686658 BSVBI22_B0514 Brucella suis VBI22 sugar ABC transporter, permease protein YP_005108521.1 497479 D 1112912 CDS YP_005108522.1 376278489 11686659 498315..499385 1 NC_016775.1 similar to GP:15073123; identified by sequence similarity; putative; Gfo/Idh/MocA family oxidoreductase 499385 11686659 BSVBI22_B0515 Brucella suis VBI22 Gfo/Idh/MocA family oxidoreductase YP_005108522.1 498315 D 1112912 CDS YP_005108523.1 376278490 11686660 499415..500416 1 NC_016775.1 similar to GP:15073122, and SP:Q01937; identified by sequence similarity; putative; sugar ABC transporter, ATP-binding protein 500416 11686660 BSVBI22_B0516 Brucella suis VBI22 sugar ABC transporter, ATP-binding protein YP_005108523.1 499415 D 1112912 CDS YP_005108524.1 376278491 11686661 500469..500720 1 NC_016775.1 hypothetical protein 500720 11686661 BSVBI22_B0517 Brucella suis VBI22 hypothetical protein YP_005108524.1 500469 D 1112912 CDS YP_005108525.1 376278492 11686662 501017..502249 1 NC_016775.1 similar to GP:15075957, and SP:P09060; identified by sequence similarity; putative; 2-oxoisovalerate dehydrogenase E1 component, alpha subunit 502249 11686662 BSVBI22_B0518 Brucella suis VBI22 2-oxoisovalerate dehydrogenase E1 component, alpha subunit YP_005108525.1 501017 D 1112912 CDS YP_005108526.1 376278493 11686663 502353..503366 1 NC_016775.1 identified by match to PFAM protein family HMM PF02780; 2-oxoisovalerate dehydrogenase, E1 component, beta subunit 503366 11686663 BSVBI22_B0519 Brucella suis VBI22 2-oxoisovalerate dehydrogenase, E1 component, beta subunit YP_005108526.1 502353 D 1112912 CDS YP_005108527.1 376278494 11686664 503367..504662 1 NC_016775.1 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; branched-chain alpha-keto acid dehydrogenase subunit E2 504662 11686664 BSVBI22_B0520 Brucella suis VBI22 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_005108527.1 503367 D 1112912 CDS YP_005108528.1 376278495 11686665 504667..506061 1 NC_016775.1 E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 506061 lpdA-3 11686665 lpdA-3 Brucella suis VBI22 dihydrolipoamide dehydrogenase YP_005108528.1 504667 D 1112912 CDS YP_005108529.1 376278496 11686666 complement(506050..506811) 1 NC_016775.1 identified by match to PFAM protein family HMM PF02104; SurF1 family protein 506811 11686666 BSVBI22_B0522 Brucella suis VBI22 SurF1 family protein YP_005108529.1 506050 R 1112912 CDS YP_005108530.1 376278497 11686667 507070..507324 1 NC_016775.1 hypothetical protein 507324 11686667 BSVBI22_B0523 Brucella suis VBI22 hypothetical protein YP_005108530.1 507070 D 1112912 CDS YP_005108531.1 376278498 11686668 complement(507505..509970) 1 NC_016775.1 similar to GB:L07807, GB:L07810, GB:L07808, GB:L07809, SP:Q05193, PID:181849, and PID:181851; identified by sequence similarity; putative; cell division protein FtsK, putative 509970 11686668 BSVBI22_B0524 Brucella suis VBI22 cell division protein FtsK, putative YP_005108531.1 507505 R 1112912 CDS YP_005108532.1 376278499 11686669 complement(510265..511287) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03576; D-aminopeptidase, putative 511287 11686669 BSVBI22_B0525 Brucella suis VBI22 D-aminopeptidase, putative YP_005108532.1 510265 R 1112912 CDS YP_005108533.1 376278500 11686670 511534..512844 1 NC_016775.1 similar to GP:15157414; identified by sequence similarity; putative; major facilitator family transporter 512844 11686670 BSVBI22_B0526 Brucella suis VBI22 major facilitator family transporter YP_005108533.1 511534 D 1112912 CDS YP_005108534.1 376278501 11686671 complement(513003..513641) 1 NC_016775.1 similar to GB:J05175, SP:P16442, PID:1783208, PID:1783212, PID:1783214, PID:1783218, PID:1783226, PID:2352626, PID:340078, and PID:992596; identified by sequence similarity; putative; alkylated DNA repair protein AlkB 513641 alkB 11686671 alkB Brucella suis VBI22 alkylated DNA repair protein AlkB YP_005108534.1 513003 R 1112912 CDS YP_005108535.1 376278502 11686672 complement(513723..515333) 1 NC_016775.1 similar to GP:15158999; identified by sequence similarity; putative; ABC transporter, ATP-binding protein 515333 11686672 BSVBI22_B0528 Brucella suis VBI22 ABC transporter, ATP-binding protein YP_005108535.1 513723 R 1112912 CDS YP_005108536.1 376278503 11686673 complement(515335..516495) 1 NC_016775.1 similar to GP:15140749; identified by sequence similarity; putative; oligopeptide ABC transporter, permease protein 516495 11686673 BSVBI22_B0529 Brucella suis VBI22 oligopeptide ABC transporter, permease protein YP_005108536.1 515335 R 1112912 CDS YP_005108537.1 376278504 11686674 complement(516461..517384) 1 NC_016775.1 similar to GP:15158997, and SP:P24138; identified by sequence similarity; putative; oligopeptide ABC transporter, permease protein 517384 11686674 BSVBI22_B0530 Brucella suis VBI22 oligopeptide ABC transporter, permease protein YP_005108537.1 516461 R 1112912 CDS YP_005108538.1 376278505 11686675 complement(517599..519176) 1 NC_016775.1 similar to GP:13235555, and SP:P77348; identified by sequence similarity; putative; oligopeptide ABC transporter, periplasmic oligopeptide-binding protein 519176 11686675 BSVBI22_B0531 Brucella suis VBI22 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein YP_005108538.1 517599 R 1112912 CDS YP_005108539.1 376278506 11686676 complement(519287..520864) 1 NC_016775.1 similar to GP:15158996, and SP:P06202; identified by sequence similarity; putative; oligopeptide ABC transporter, periplasmic oligopeptide-binding protein 520864 11686676 BSVBI22_B0532 Brucella suis VBI22 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein YP_005108539.1 519287 R 1112912 CDS YP_005108540.1 376278507 11686677 complement(520958..521128) 1 NC_016775.1 hypothetical protein 521128 11686677 BSVBI22_B0533 Brucella suis VBI22 hypothetical protein YP_005108540.1 520958 R 1112912 CDS YP_005108541.1 376278508 11686678 complement(521291..521638) 1 NC_016775.1 similar to GP:15074850; identified by sequence similarity; putative; hypothetical protein 521638 11686678 BSVBI22_B0534 Brucella suis VBI22 hypothetical protein YP_005108541.1 521291 R 1112912 CDS YP_005108542.1 376278509 11686679 complement(521892..522116) 1 NC_016775.1 hypothetical protein 522116 11686679 BSVBI22_B0535 Brucella suis VBI22 hypothetical protein YP_005108542.1 521892 R 1112912 CDS YP_005108543.1 376278510 11686680 522433..523446 1 NC_016775.1 similar to GP:15140313; identified by sequence similarity; putative; NAD-dependent epimerase/dehydratase family protein 523446 11686680 BSVBI22_B0536 Brucella suis VBI22 NAD-dependent epimerase/dehydratase family protein YP_005108543.1 522433 D 1112912 CDS YP_005108544.1 376278511 11686681 523446..524432 1 NC_016775.1 similar to SP:P23157, GB:X55942, and PID:46921; identified by sequence similarity; putative; UDP-glucose 4-epimerase 524432 galE-2 11686681 galE-2 Brucella suis VBI22 UDP-glucose 4-epimerase YP_005108544.1 523446 D 1112912 CDS YP_005108545.1 376278512 11686682 524429..526273 1 NC_016775.1 similar to GP:15140315; identified by sequence similarity; putative; glycosyl transferase, group 2 family protein 526273 11686682 BSVBI22_B0538 Brucella suis VBI22 glycosyl transferase, group 2 family protein YP_005108545.1 524429 D 1112912 CDS YP_005108546.1 376278513 11686683 526288..527712 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00745; UDP-glucose 6-dehydrogenase 527712 ugd 11686683 ugd Brucella suis VBI22 UDP-glucose 6-dehydrogenase YP_005108546.1 526288 D 1112912 CDS YP_005108547.1 376278514 11686684 527702..528247 1 NC_016775.1 similar to GP:15140316, and GP:15140316; identified by sequence similarity; putative; hypothetical protein 528247 11686684 BSVBI22_B0540 Brucella suis VBI22 hypothetical protein YP_005108547.1 527702 D 1112912 CDS YP_005108548.1 376278515 11686685 528297..529241 1 NC_016775.1 similar to GP:15140317; identified by sequence similarity; putative; endoglucanase family protein 529241 11686685 BSVBI22_B0541 Brucella suis VBI22 endoglucanase family protein YP_005108548.1 528297 D 1112912 CDS YP_005108549.1 376278516 11686686 529238..529855 1 NC_016775.1 similar to GP:15140318, and GP:15140318; identified by sequence similarity; putative; hypothetical protein 529855 11686686 BSVBI22_B0542 Brucella suis VBI22 hypothetical protein YP_005108549.1 529238 D 1112912 CDS YP_005108550.1 376278517 11686687 complement(529931..530257) 1 NC_016775.1 similar to GP:15160059; identified by sequence similarity; putative; hypothetical protein 530257 11686687 BSVBI22_B0543 Brucella suis VBI22 hypothetical protein YP_005108550.1 529931 R 1112912 CDS YP_005108551.1 376278518 11686688 complement(530400..531521) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator 531521 11686688 BSVBI22_B0544 Brucella suis VBI22 AraC family transcriptional regulator YP_005108551.1 530400 R 1112912 CDS YP_005108552.1 376278519 11686690 complement(532312..532623) 1 NC_016775.1 similar to GB:X07282, SP:P10826, PID:184477, PID:32026, PID:35883, GB:D38554, PID:1354931, and PID:559705; identified by sequence similarity; putative; IS711, transposase orfA 532623 11686690 BSVBI22_B0546 Brucella suis VBI22 IS711, transposase orfA YP_005108552.1 532312 R 1112912 CDS YP_005108553.1 376278520 11686691 complement(532680..534644) 1 NC_016775.1 identified by match to PFAM protein family HMM PF02566; cell wall surface protein, putative 534644 11686691 BSVBI22_B0547 Brucella suis VBI22 cell wall surface protein, putative YP_005108553.1 532680 R 1112912 CDS YP_005108554.1 376278521 11686693 complement(535220..535825) 1 NC_016775.1 similar to SP:P14040, GB:X15970, and PID:44784; identified by sequence similarity; putative; IS66 family orf4 535825 11686693 BSVBI22_B0549 Brucella suis VBI22 IS66 family orf4 YP_005108554.1 535220 R 1112912 CDS YP_005108555.1 376278522 11686694 complement(535822..537393) 1 NC_016775.1 similar to GP:15140549, SP:P37811, GB:Z28592, PID:433988, and GB:AL009126; identified by sequence similarity; putative; IS66 family orf3 537393 11686694 BSVBI22_B0550 Brucella suis VBI22 IS66 family orf3 YP_005108555.1 535822 R 1112912 CDS YP_005108556.1 376278523 11686695 complement(537443..537829) 1 NC_016775.1 similar to GP:15076151, SP:P37811, GB:Z28592, PID:433988, and GB:AL009126; identified by sequence similarity; putative; IS66 family orf2 537829 11686695 BSVBI22_B0551 Brucella suis VBI22 IS66 family orf2 YP_005108556.1 537443 R 1112912 CDS YP_005108557.1 376278524 11686696 complement(537793..538260) 1 NC_016775.1 similar to GP:15076150, and GP:15076150; identified by sequence similarity; putative; IS66 family Orf1 538260 11686696 BSVBI22_B0552 Brucella suis VBI22 IS66 family Orf1 YP_005108557.1 537793 R 1112912 CDS YP_005108558.1 376278525 11686697 complement(538341..538736) 1 NC_016775.1 hypothetical protein 538736 11686697 BSVBI22_B0553 Brucella suis VBI22 hypothetical protein YP_005108558.1 538341 R 1112912 CDS YP_005108559.1 376278526 11686698 539404..539877 1 NC_016775.1 hypothetical protein 539877 11686698 BSVBI22_B0554 Brucella suis VBI22 hypothetical protein YP_005108559.1 539404 D 1112912 CDS YP_005108560.1 376278527 11686700 540350..540808 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00011; hypothetical protein 540808 11686700 BSVBI22_B0555 Brucella suis VBI22 hypothetical protein YP_005108560.1 540350 D 1112912 CDS YP_005108561.1 376278528 11686701 541054..541515 1 NC_016775.1 rhizobial iron regulator; in Sinorhizobium meliloti mutations in this gene affect the expression of a number of iron-responsive operons; iron-responsive transcriptional regulator 541515 rirA 11686701 rirA Brucella suis VBI22 iron-responsive transcriptional regulator YP_005108561.1 541054 D 1112912 CDS YP_005108562.1 376278529 11686702 541632..541946 1 NC_016775.1 similar to GP:13277326, and GP:13277326; identified by sequence similarity; putative; hypothetical protein 541946 11686702 BSVBI22_B0557 Brucella suis VBI22 hypothetical protein YP_005108562.1 541632 D 1112912 CDS YP_005108563.1 376278530 11686703 542403..542714 1 NC_016775.1 similar to GP:15076196; identified by sequence similarity; putative; hypothetical protein 542714 11686703 BSVBI22_B0558 Brucella suis VBI22 hypothetical protein YP_005108563.1 542403 D 1112912 CDS YP_005108564.1 376278531 11686704 542680..543165 1 NC_016775.1 similar to SP:P22759; identified by sequence similarity; putative; bacterioferritin 543165 bfr 11686704 bfr Brucella suis VBI22 bacterioferritin YP_005108564.1 542680 D 1112912 CDS YP_005108565.1 376278532 11686705 543329..544642 1 NC_016775.1 identified by match to PFAM protein family HMM PF00919; hypothetical protein 544642 11686705 BSVBI22_B0560 Brucella suis VBI22 hypothetical protein YP_005108565.1 543329 D 1112912 CDS YP_005108566.1 376278533 11686706 complement(544782..545849) 1 NC_016775.1 similar to GP:15156897; identified by sequence similarity; putative; bmp family protein 545849 11686706 BSVBI22_B0561 Brucella suis VBI22 bmp family protein YP_005108566.1 544782 R 1112912 CDS YP_005108567.1 376278534 11686707 complement(545932..546852) 1 NC_016775.1 similar to GP:15156898; identified by sequence similarity; putative; ABC transporter, permease protein 546852 11686707 BSVBI22_B0562 Brucella suis VBI22 ABC transporter, permease protein YP_005108567.1 545932 R 1112912 CDS YP_005108568.1 376278535 11686708 complement(546857..547939) 1 NC_016775.1 similar to GP:13937515; identified by sequence similarity; putative; ABC transporter, permease protein 547939 11686708 BSVBI22_B0563 Brucella suis VBI22 ABC transporter, permease protein YP_005108568.1 546857 R 1112912 CDS YP_005108569.1 376278536 11686709 complement(547939..549501) 1 NC_016775.1 similar to GP:13937516; identified by sequence similarity; putative; ABC transporter, ATP-binding protein 549501 11686709 BSVBI22_B0564 Brucella suis VBI22 ABC transporter, ATP-binding protein YP_005108569.1 547939 R 1112912 CDS YP_005108570.1 376278537 11686710 complement(549605..550579) 1 NC_016775.1 similar to GP:15074605; identified by sequence similarity; putative; quinone oxidoreductase 550579 qor 11686710 qor Brucella suis VBI22 quinone oxidoreductase YP_005108570.1 549605 R 1112912 CDS YP_005108571.1 376278538 11686711 complement(550576..551376) 1 NC_016775.1 similar to GP:6739568; identified by sequence similarity; putative; phosphatidylcholine synthase 551376 pcs 11686711 pcs Brucella suis VBI22 phosphatidylcholine synthase YP_005108571.1 550576 R 1112912 CDS YP_005108572.1 376278539 11686712 551592..552950 1 NC_016775.1 similar to SP:P25534; identified by sequence similarity; putative; 2-octaprenyl-6-methoxyphenyl hydroxylase 552950 ubiH 11686712 ubiH Brucella suis VBI22 2-octaprenyl-6-methoxyphenyl hydroxylase YP_005108572.1 551592 D 1112912 CDS YP_005108573.1 376278540 11686713 553023..553361 1 NC_016775.1 similar to GP:15074574; identified by sequence similarity; putative; hypothetical protein 553361 11686713 BSVBI22_B0568 Brucella suis VBI22 hypothetical protein YP_005108573.1 553023 D 1112912 CDS YP_005108574.1 376278541 11686714 complement(553494..554111) 1 NC_016775.1 similar to GP:14021474; identified by sequence similarity; putative; hypothetical protein 554111 11686714 BSVBI22_B0569 Brucella suis VBI22 hypothetical protein YP_005108574.1 553494 R 1112912 CDS YP_005108575.1 376278542 11686715 554456..556303 1 NC_016775.1 similar to GP:15074576; identified by sequence similarity; putative; peptide ABC transporter, periplasmic peptide-binding protein 556303 11686715 BSVBI22_B0570 Brucella suis VBI22 peptide ABC transporter, periplasmic peptide-binding protein YP_005108575.1 554456 D 1112912 CDS YP_005108576.1 376278543 11686716 556483..557157 1 NC_016775.1 identified by match to PFAM protein family HMM PF03046; frnE protein, putative 557157 11686716 BSVBI22_B0571 Brucella suis VBI22 frnE protein, putative YP_005108576.1 556483 D 1112912 CDS YP_005108577.1 376278544 11686717 complement(557333..557731) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00903; fosfomycin resistance family protein 557731 11686717 BSVBI22_B0572 Brucella suis VBI22 fosfomycin resistance family protein YP_005108577.1 557333 R 1112912 CDS YP_005108578.1 376278545 11686718 complement(557824..561192) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01587; transcription-repair coupling factor 561192 mfd 11686718 mfd Brucella suis VBI22 transcription-repair coupling factor YP_005108578.1 557824 R 1112912 CDS YP_005108579.1 376278546 11686719 complement(561347..561634) 1 NC_016775.1 similar to GP:15074586, and GP:15074586; identified by sequence similarity; putative; hypothetical protein 561634 11686719 BSVBI22_B0574 Brucella suis VBI22 hypothetical protein YP_005108579.1 561347 R 1112912 CDS YP_005108580.1 376278547 11686720 561773..563893 1 NC_016775.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 563893 recG 11686720 recG Brucella suis VBI22 ATP-dependent DNA helicase RecG YP_005108580.1 561773 D 1112912 CDS YP_005108581.1 376278548 11686721 complement(564048..565871) 1 NC_016775.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 565871 glmS 11686721 glmS Brucella suis VBI22 glucosamine--fructose-6-phosphate aminotransferase YP_005108581.1 564048 R 1112912 CDS YP_005108582.1 376278549 11686722 complement(565975..567339) 1 NC_016775.1 similar to GB:K03195, SP:P11166, and PID:183303; identified by sequence similarity; putative; UDP-N-acetylglucosamine pyrophosphorylase 567339 glmU 11686722 glmU Brucella suis VBI22 UDP-N-acetylglucosamine pyrophosphorylase YP_005108582.1 565975 R 1112912 CDS YP_005108583.1 376278550 11686723 complement(567421..568182) 1 NC_016775.1 similar to GP:6714962; identified by sequence similarity; putative; cytochrome c-type biogenesis protein CcdA 568182 ccdA 11686723 ccdA Brucella suis VBI22 cytochrome c-type biogenesis protein CcdA YP_005108583.1 567421 R 1112912 CDS YP_005108584.1 376278551 11686724 568331..570973 1 NC_016775.1 similar to GP:15074112; identified by sequence similarity; putative; hypothetical protein 570973 11686724 BSVBI22_B0579 Brucella suis VBI22 hypothetical protein YP_005108584.1 568331 D 1112912 CDS YP_005108585.1 376278552 11686725 571222..572382 1 NC_016775.1 similar to GP:15157711, and GP:1196970; identified by sequence similarity; putative; hypothetical protein 572382 11686725 BSVBI22_B0580 Brucella suis VBI22 hypothetical protein YP_005108585.1 571222 D 1112912 CDS YP_005108586.1 376278553 11686727 complement(572886..573386) 1 NC_016775.1 similar to GP:3236220; identified by sequence similarity; putative; hypothetical protein 573386 11686727 BSVBI22_B0581 Brucella suis VBI22 hypothetical protein YP_005108586.1 572886 R 1112912 CDS YP_005108587.1 376278554 11686728 573704..575095 1 NC_016775.1 identified by match to PFAM protein family HMM PF00989; sensory box protein 575095 11686728 BSVBI22_B0582 Brucella suis VBI22 sensory box protein YP_005108587.1 573704 D 1112912 CDS YP_005108588.1 376278555 11686729 575223..576026 1 NC_016775.1 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism; lipoyltransferase 576026 lipB 11686729 lipB Brucella suis VBI22 lipoyltransferase YP_005108588.1 575223 D 1112912 CDS YP_005108589.1 376278556 11686730 complement(576030..576959) 1 NC_016775.1 similar to GP:15156645; identified by sequence similarity; putative; hypothetical protein 576959 11686730 BSVBI22_B0584 Brucella suis VBI22 hypothetical protein YP_005108589.1 576030 R 1112912 CDS YP_005108590.1 376278557 11686731 577264..579363 1 NC_016775.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 579363 parE 11686731 parE Brucella suis VBI22 DNA topoisomerase IV subunit B YP_005108590.1 577264 D 1112912 CDS YP_005108591.1 376278558 11686732 complement(579369..579551) 1 NC_016775.1 hypothetical protein 579551 11686732 BSVBI22_B0586 Brucella suis VBI22 hypothetical protein YP_005108591.1 579369 R 1112912 CDS YP_005108592.1 376278559 11686733 complement(579536..579760) 1 NC_016775.1 hypothetical protein 579760 11686733 BSVBI22_B0587 Brucella suis VBI22 hypothetical protein YP_005108592.1 579536 R 1112912 CDS YP_005108593.1 376278560 11686734 complement(579785..581266) 1 NC_016775.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 581266 gatA 11686734 gatA Brucella suis VBI22 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_005108593.1 579785 R 1112912 CDS YP_005108594.1 376278561 11686735 complement(581325..581612) 1 NC_016775.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 581612 gatC 11686735 gatC Brucella suis VBI22 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_005108594.1 581325 R 1112912 CDS YP_005108595.1 376278562 11686736 complement(581707..582420) 1 NC_016775.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; metal-dependent hydrolase 582420 11686736 BSVBI22_B0590 Brucella suis VBI22 metal-dependent hydrolase YP_005108595.1 581707 R 1112912 CDS YP_005108596.1 376278563 11686737 582520..583008 1 NC_016775.1 similar to GP:15156369, and GP:15074241; identified by sequence similarity; putative; hypothetical protein 583008 11686737 BSVBI22_B0591 Brucella suis VBI22 hypothetical protein YP_005108596.1 582520 D 1112912 CDS YP_005108597.1 376278564 11686738 complement(582993..584648) 1 NC_016775.1 identified by match to PFAM protein family HMM PF02771; acyl-CoA dehydrogenase family protein 584648 11686738 BSVBI22_B0592 Brucella suis VBI22 acyl-CoA dehydrogenase family protein YP_005108597.1 582993 R 1112912 CDS YP_005108598.1 376278565 11686739 584805..585773 1 NC_016775.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 585773 pyrB 11686739 pyrB Brucella suis VBI22 aspartate carbamoyltransferase catalytic subunit YP_005108598.1 584805 D 1112912 CDS YP_005108599.1 376278566 11686740 585770..587056 1 NC_016775.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 587056 pyrC-2 11686740 pyrC-2 Brucella suis VBI22 dihydroorotase YP_005108599.1 585770 D 1112912 CDS YP_005108600.1 376278567 11686741 587131..587736 1 NC_016775.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 587736 11686741 BSVBI22_B0595 Brucella suis VBI22 putative glycerol-3-phosphate acyltransferase PlsY YP_005108600.1 587131 D 1112912 CDS YP_005108601.1 376278568 11686742 587733..588914 1 NC_016775.1 similar to GP:15156358; identified by sequence similarity; putative; DNA processing protein DprA, putative 588914 11686742 BSVBI22_B0596 Brucella suis VBI22 DNA processing protein DprA, putative YP_005108601.1 587733 D 1112912 CDS YP_005108602.1 376278569 11686743 complement(588924..589091) 1 NC_016775.1 hypothetical protein 589091 11686743 BSVBI22_B0597 Brucella suis VBI22 hypothetical protein YP_005108602.1 588924 R 1112912 CDS YP_005108603.1 376278570 11686744 589347..591980 1 NC_016775.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 591980 topA 11686744 topA Brucella suis VBI22 DNA topoisomerase I YP_005108603.1 589347 D 1112912 CDS YP_005108604.1 376278571 11686745 591984..594335 1 NC_016775.1 similar to SP:P21499; identified by sequence similarity; putative; VacB/RNase II family exoribonuclease 594335 11686745 BSVBI22_B0599 Brucella suis VBI22 VacB/RNase II family exoribonuclease YP_005108604.1 591984 D 1112912 CDS YP_005108605.1 376278572 11686746 594335..594796 1 NC_016775.1 hypothetical protein 594796 11686746 BSVBI22_B0600 Brucella suis VBI22 hypothetical protein YP_005108605.1 594335 D 1112912 CDS YP_005108606.1 376278573 11686747 594805..595536 1 NC_016775.1 similar to GP:6525218; identified by sequence similarity; putative; MutT/nudix family protein 595536 11686747 BSVBI22_B0601 Brucella suis VBI22 MutT/nudix family protein YP_005108606.1 594805 D 1112912 CDS YP_005108607.1 376278574 11686748 595611..596753 1 NC_016775.1 similar to GP:6525219; identified by sequence similarity; putative; major facilitator family transporter 596753 11686748 BSVBI22_B0602 Brucella suis VBI22 major facilitator family transporter YP_005108607.1 595611 D 1112912 CDS YP_005108608.1 376278575 11686749 596912..597079 1 NC_016775.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 597079 rpmG 11686749 rpmG Brucella suis VBI22 50S ribosomal protein L33 YP_005108608.1 596912 D 1112912 CDS YP_005108609.1 376278576 11686750 complement(597186..598571) 1 NC_016775.1 involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD 598571 pleD 11686750 pleD Brucella suis VBI22 response regulator PleD YP_005108609.1 597186 R 1112912 CDS YP_005108610.1 376278577 11686751 complement(598568..598699) 1 NC_016775.1 hypothetical protein 598699 11686751 BSVBI22_B0605 Brucella suis VBI22 hypothetical protein YP_005108610.1 598568 R 1112912 CDS YP_005108611.1 376278578 11686752 complement(598692..599063) 1 NC_016775.1 similar to GP:6513589; identified by sequence similarity; putative; polar differentiation response regulator 599063 divK 11686752 divK Brucella suis VBI22 polar differentiation response regulator YP_005108611.1 598692 R 1112912 CDS YP_005108612.1 376278579 11686753 599166..599531 1 NC_016775.1 similar to GP:15074224; identified by sequence similarity; putative; hypothetical protein 599531 11686753 BSVBI22_B0607 Brucella suis VBI22 hypothetical protein YP_005108612.1 599166 D 1112912 CDS YP_005108613.1 376278580 11686754 complement(599587..600096) 1 NC_016775.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 600096 11686754 BSVBI22_B0608 Brucella suis VBI22 nucleoside diphosphate kinase regulator YP_005108613.1 599587 R 1112912 CDS YP_005108614.1 376278581 11686755 600547..601884 1 NC_016775.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 601884 11686755 BSVBI22_B0609 Brucella suis VBI22 DNA polymerase IV YP_005108614.1 600547 D 1112912 CDS YP_005108615.1 376278582 11686756 602060..604249 1 NC_016775.1 similar to GP:15156313, and GP:15074191; identified by sequence similarity; putative; hypothetical protein 604249 11686756 BSVBI22_B0610 Brucella suis VBI22 hypothetical protein YP_005108615.1 602060 D 1112912 CDS YP_005108616.1 376278583 11686757 complement(604229..604351) 1 NC_016775.1 hypothetical protein 604351 11686757 BSVBI22_B0611 Brucella suis VBI22 hypothetical protein YP_005108616.1 604229 R 1112912 CDS YP_005108617.1 376278584 11686759 complement(604778..605500) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00254; GGDEF domain-containing protein 605500 11686759 BSVBI22_B0612 Brucella suis VBI22 GGDEF domain-containing protein YP_005108617.1 604778 R 1112912 CDS YP_005108618.1 376278585 11686760 complement(606173..606271) 1 NC_016775.1 hypothetical protein 606271 11686760 BSVBI22_B0613 Brucella suis VBI22 hypothetical protein YP_005108618.1 606173 R 1112912 CDS YP_005108619.1 376278586 11686761 complement(606307..606420) 1 NC_016775.1 hypothetical protein 606420 11686761 BSVBI22_B0614 Brucella suis VBI22 hypothetical protein YP_005108619.1 606307 R 1112912 CDS YP_005108620.1 376278587 11686762 complement(606398..606775) 1 NC_016775.1 similar to SP:P09795, and PID:154350; identified by sequence similarity; putative; endonuclease V 606775 11686762 BSVBI22_B0615 Brucella suis VBI22 endonuclease V YP_005108620.1 606398 R 1112912 CDS YP_005108621.1 376278588 11686763 606916..607221 1 NC_016775.1 hypothetical protein 607221 11686763 BSVBI22_B0616 Brucella suis VBI22 hypothetical protein YP_005108621.1 606916 D 1112912 CDS YP_005108622.1 376278589 11686764 607366..607554 1 NC_016775.1 hypothetical protein 607554 11686764 BSVBI22_B0617 Brucella suis VBI22 hypothetical protein YP_005108622.1 607366 D 1112912 CDS YP_005108623.1 376278590 11686765 607605..607898 1 NC_016775.1 hypothetical protein 607898 11686765 BSVBI22_B0618 Brucella suis VBI22 hypothetical protein YP_005108623.1 607605 D 1112912 CDS YP_005108624.1 376278591 11686766 607992..608666 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01406; exonuclease, putative 608666 11686766 BSVBI22_B0619 Brucella suis VBI22 exonuclease, putative YP_005108624.1 607992 D 1112912 CDS YP_005108625.1 376278592 11686768 609042..609323 1 NC_016775.1 similar to GP:15074546, and GP:15074546; identified by sequence similarity; putative; hypothetical protein 609323 11686768 BSVBI22_B0620 Brucella suis VBI22 hypothetical protein YP_005108625.1 609042 D 1112912 CDS YP_005108626.1 376278593 11686769 complement(609424..610383) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator 610383 11686769 BSVBI22_B0621 Brucella suis VBI22 AraC family transcriptional regulator YP_005108626.1 609424 R 1112912 CDS YP_005108627.1 376278594 11686770 complement(610551..610712) 1 NC_016775.1 hypothetical protein 610712 11686770 BSVBI22_B0622 Brucella suis VBI22 hypothetical protein YP_005108627.1 610551 R 1112912 CDS YP_005108628.1 376278595 11686771 complement(610738..611988) 1 NC_016775.1 similar to GP:15073672, and SP:Q98B75; identified by sequence similarity; putative; amino acid dehydrogenase, putative 611988 11686771 BSVBI22_B0623 Brucella suis VBI22 amino acid dehydrogenase, putative YP_005108628.1 610738 R 1112912 CDS YP_005108629.1 376278596 11686772 complement(612077..612838) 1 NC_016775.1 similar to SP:P33548, PID:155324, and PID:155328; identified by sequence similarity; putative; amino acid ABC transporter, periplasmic amino acid-binding protein 612838 11686772 BSVBI22_B0624 Brucella suis VBI22 amino acid ABC transporter, periplasmic amino acid-binding protein YP_005108629.1 612077 R 1112912 CDS YP_005108630.1 376278597 11686773 complement(612994..613767) 1 NC_016775.1 similar to SP:P33548, PID:155324, and PID:155328; identified by sequence similarity; putative; amino acid ABC transporter, periplasmic amino acid-binding protein 613767 11686773 BSVBI22_B0625 Brucella suis VBI22 amino acid ABC transporter, periplasmic amino acid-binding protein YP_005108630.1 612994 R 1112912 CDS YP_005108631.1 376278598 11686774 complement(613952..615055) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00899; hypothetical protein 615055 11686774 BSVBI22_B0626 Brucella suis VBI22 hypothetical protein YP_005108631.1 613952 R 1112912 CDS YP_005108632.1 376278599 11686775 615157..615606 1 NC_016775.1 identified by match to PFAM protein family HMM PF01047; AsnC family transcriptional regulator 615606 11686775 BSVBI22_B0627 Brucella suis VBI22 AsnC family transcriptional regulator YP_005108632.1 615157 D 1112912 CDS YP_005108633.1 376278600 11686776 615886..617613 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01409; twin-arginine translocation pathway signal sequence domain-containing protein 617613 11686776 BSVBI22_B0628 Brucella suis VBI22 twin-arginine translocation pathway signal sequence domain-containing protein YP_005108633.1 615886 D 1112912 CDS YP_005108634.1 376278601 11686777 complement(617724..618926) 1 NC_016775.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase 618926 pcaF 11686777 pcaF Brucella suis VBI22 beta-ketoadipyl CoA thiolase YP_005108634.1 617724 R 1112912 CDS YP_005108635.1 376278602 11686778 complement(618935..619624) 1 NC_016775.1 similar to GP:15158666, and SP:Q01104; identified by sequence similarity; putative; 3-oxoadipate CoA-transferase, beta subunit 619624 pcaJ 11686778 pcaJ Brucella suis VBI22 3-oxoadipate CoA-transferase, beta subunit YP_005108635.1 618935 R 1112912 CDS YP_005108636.1 376278603 11686779 complement(619621..620328) 1 NC_016775.1 similar to GP:15158667, and SP:Q01103; identified by sequence similarity; putative; 3-oxoadipate CoA-transferase, alpha subunit 620328 pcaI 11686779 pcaI Brucella suis VBI22 3-oxoadipate CoA-transferase, alpha subunit YP_005108636.1 619621 R 1112912 CDS YP_005108637.1 376278604 11686780 620512..621282 1 NC_016775.1 similar to GP:15141386; identified by sequence similarity; putative; transcriptional regulator PcaR, putative 621282 11686780 BSVBI22_B0632 Brucella suis VBI22 transcriptional regulator PcaR, putative YP_005108637.1 620512 D 1112912 CDS YP_005108638.1 376278605 11686781 complement(621289..622206) 1 NC_016775.1 similar to GP:6682325; identified by sequence similarity; putative; pobR protein 622206 pobR 11686781 pobR Brucella suis VBI22 pobR protein YP_005108638.1 621289 R 1112912 CDS YP_005108639.1 376278606 11686782 622319..623488 1 NC_016775.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 4-hydroxybenzoate 3-monooxygenase 623488 pobA 11686782 pobA Brucella suis VBI22 4-hydroxybenzoate 3-monooxygenase YP_005108639.1 622319 D 1112912 CDS YP_005108640.1 376278607 11686783 complement(623898..624806) 1 NC_016775.1 similar to GP:15141380, GB:D21235, SP:P54725, PID:1905912, and PID:498146; identified by sequence similarity; putative; transcriptional regulator PcaQ 624806 pcaQ 11686783 pcaQ Brucella suis VBI22 transcriptional regulator PcaQ YP_005108640.1 623898 R 1112912 CDS YP_005108641.1 376278608 11686784 624900..625703 1 NC_016775.1 similar to GP:15141379, and SP:P00632; identified by sequence similarity; putative; 3-oxoadipate enol-lactone hydrolase 625703 pcaL 11686784 pcaL Brucella suis VBI22 3-oxoadipate enol-lactone hydrolase YP_005108641.1 624900 D 1112912 CDS YP_005108642.1 376278609 11686785 625707..626123 1 NC_016775.1 similar to GP:15141378; identified by sequence similarity; putative; 4-carboxymuconolactone decarboxylase 626123 pcaC 11686785 pcaC Brucella suis VBI22 4-carboxymuconolactone decarboxylase YP_005108642.1 625707 D 1112912 CDS YP_005108643.1 376278610 11686786 626120..626860 1 NC_016775.1 similar to GP:11037223, and SP:P00437; identified by sequence similarity; putative; protocatechuate 3,4-dioxygenase, beta subunit 626860 pcaH 11686786 pcaH Brucella suis VBI22 protocatechuate 3,4-dioxygenase, beta subunit YP_005108643.1 626120 D 1112912 CDS YP_005108644.1 376278611 11686787 626862..627479 1 NC_016775.1 similar to GP:11037224, GB:M12783, GB:X02811, GB:M19719, GB:X03702, GB:K01918, GB:X03493, GB:Y00389, GB:K01402, GB:X02745, GB:K01399, GB:X00560, GB:K01915, GB:K01917, GB:K01401, GB:X00562, GB:K01916, GB:K01400, GB:X00561, GB:K01913, GB:K01914, GB:J00121, GB:K01398, GB:X02744, GB:M32009, SP:P01127, PID:1335308, PID:1335309, PID:1335310, PID:1335311, PID:1621242, PID:1888419, PID:2294400, PID:2294421, PID:2294425, PID:2297379, PID:30247, PID:338199, PID:338209, PID:338211, PID:35372, PID:35375, PID:35377, PID:36481, and PID:951025; identified by sequence similarity; putative; protocatechuate 3,4-dioxygenase, alpha subunit 627479 pcaG 11686787 pcaG Brucella suis VBI22 protocatechuate 3,4-dioxygenase, alpha subunit YP_005108644.1 626862 D 1112912 CDS YP_005108645.1 376278612 11686788 627483..628547 1 NC_016775.1 Catalyzes the cycloisomerization of cis,cis-muconate; 3-carboxy-cis,cis-muconate cycloisomerase 628547 11686788 BSVBI22_B0640 Brucella suis VBI22 3-carboxy-cis,cis-muconate cycloisomerase YP_005108645.1 627483 D 1112912 CDS YP_005108646.1 376278613 11686789 628683..629855 1 NC_016775.1 similar to GP:15158698; identified by sequence similarity; putative; amino acid ABC transporter, periplasmic amino-acid binding protein 629855 11686789 BSVBI22_B0641 Brucella suis VBI22 amino acid ABC transporter, periplasmic amino-acid binding protein YP_005108646.1 628683 D 1112912 CDS YP_005108647.1 376278614 11686790 630028..630897 1 NC_016775.1 similar to GP:15158699; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, permease protein 630897 11686790 BSVBI22_B0642 Brucella suis VBI22 branched-chain amino acid ABC transporter, permease protein YP_005108647.1 630028 D 1112912 CDS YP_005108648.1 376278615 11686791 630894..631880 1 NC_016775.1 similar to GP:15158700; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, permease protein 631880 11686791 BSVBI22_B0643 Brucella suis VBI22 branched-chain amino acid ABC transporter, permease protein YP_005108648.1 630894 D 1112912 CDS YP_005108649.1 376278616 11686792 631877..632626 1 NC_016775.1 similar to GP:15158701; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, ATP-binding protein 632626 11686792 BSVBI22_B0644 Brucella suis VBI22 branched-chain amino acid ABC transporter, ATP-binding protein YP_005108649.1 631877 D 1112912 CDS YP_005108650.1 376278617 11686793 632623..633339 1 NC_016775.1 similar to GP:15158702; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, ATP-binding protein 633339 11686793 BSVBI22_B0645 Brucella suis VBI22 branched-chain amino acid ABC transporter, ATP-binding protein YP_005108650.1 632623 D 1112912 CDS YP_005108651.1 376278618 11686794 complement(633340..635085) 1 NC_016775.1 similar to GB:Y00636, GB:X06296, SP:P19256, PID:34347, PID:34350, and PID:540515; identified by sequence similarity; putative; adenine deaminase 635085 ade 11686794 ade Brucella suis VBI22 adenine deaminase YP_005108651.1 633340 R 1112912 CDS YP_005108652.1 376278619 11686795 635244..636284 1 NC_016775.1 similar to GP:15157708; identified by sequence similarity; putative; renal dipeptidase family protein 636284 11686795 BSVBI22_B0647 Brucella suis VBI22 renal dipeptidase family protein YP_005108652.1 635244 D 1112912 CDS YP_005108653.1 376278620 11686796 636617..637918 1 NC_016775.1 similar to GP:15140275, and GP:43244; identified by sequence similarity; putative; glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein 637918 ugpB 11686796 ugpB Brucella suis VBI22 glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein YP_005108653.1 636617 D 1112912 CDS YP_005108654.1 376278621 11686797 637991..638872 1 NC_016775.1 similar to GP:15140276; identified by sequence similarity; putative; glycerol-3-phosphate ABC transporter, permease protein 638872 ugpA 11686797 ugpA Brucella suis VBI22 glycerol-3-phosphate ABC transporter, permease protein YP_005108654.1 637991 D 1112912 CDS YP_005108655.1 376278622 11686798 638884..639732 1 NC_016775.1 similar to GP:15160208; identified by sequence similarity; putative; glycerol-3-phosphate ABC transporter, permease protein 639732 ugpE 11686798 ugpE Brucella suis VBI22 glycerol-3-phosphate ABC transporter, permease protein YP_005108655.1 638884 D 1112912 CDS YP_005108656.1 376278623 11686799 639732..640787 1 NC_016775.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 640787 ugpC 11686799 ugpC Brucella suis VBI22 glycerol-3-phosphate transporter ATP-binding subunit YP_005108656.1 639732 D 1112912 CDS YP_005108657.1 376278624 11686800 640961..642820 1 NC_016775.1 similar to GP:15075030; identified by sequence similarity; putative; TrkA family protein 642820 11686800 BSVBI22_B0652 Brucella suis VBI22 TrkA family protein YP_005108657.1 640961 D 1112912 CDS YP_005108658.1 376278625 11686801 complement(642898..643497) 1 NC_016775.1 similar to GP:15074401; identified by sequence similarity; putative; cytidine/deoxycytidylate deaminase family protein 643497 11686801 BSVBI22_B0653 Brucella suis VBI22 cytidine/deoxycytidylate deaminase family protein YP_005108658.1 642898 R 1112912 CDS YP_005108659.1 376278626 11686802 complement(643558..644850) 1 NC_016775.1 similar to GP:15140670; identified by sequence similarity; putative; uracil-xanthine permease, putative 644850 11686802 BSVBI22_B0654 Brucella suis VBI22 uracil-xanthine permease, putative YP_005108659.1 643558 R 1112912 CDS YP_005108660.1 376278627 11686803 complement(645119..645283) 1 NC_016775.1 hypothetical protein 645283 11686803 BSVBI22_B0655 Brucella suis VBI22 hypothetical protein YP_005108660.1 645119 R 1112912 CDS YP_005108661.1 376278628 11686805 645976..646158 1 NC_016775.1 hypothetical protein 646158 11686805 BSVBI22_B0657 Brucella suis VBI22 hypothetical protein YP_005108661.1 645976 D 1112912 CDS YP_005108662.1 376278629 11686806 complement(646162..646299) 1 NC_016775.1 similar to GP:15073153; identified by sequence similarity; putative; hypothetical protein 646299 11686806 BSVBI22_B0658 Brucella suis VBI22 hypothetical protein YP_005108662.1 646162 R 1112912 CDS YP_005108663.1 376278630 11686807 646558..647475 1 NC_016775.1 similar to GP:15156879; identified by sequence similarity; putative; hypothetical protein 647475 11686807 BSVBI22_B0659 Brucella suis VBI22 hypothetical protein YP_005108663.1 646558 D 1112912 CDS YP_005108664.1 376278631 11686809 648435..648626 1 NC_016775.1 hypothetical protein 648626 11686809 BSVBI22_B0661 Brucella suis VBI22 hypothetical protein YP_005108664.1 648435 D 1112912 CDS YP_005108665.1 376278632 11686810 648623..649384 1 NC_016775.1 identified by match to PFAM protein family HMM PF03647; hypothetical protein 649384 11686810 BSVBI22_B0662 Brucella suis VBI22 hypothetical protein YP_005108665.1 648623 D 1112912 CDS YP_005108666.1 376278633 11686811 649456..651111 1 NC_016775.1 proposed role in polysaccahride synthesis; putative FAD-binding dehydrogenase 651111 11686811 BSVBI22_B0663 Brucella suis VBI22 putative FAD-binding dehydrogenase YP_005108666.1 649456 D 1112912 CDS YP_005108667.1 376278634 11686812 651120..651644 1 NC_016775.1 hypothetical protein 651644 11686812 BSVBI22_B0664 Brucella suis VBI22 hypothetical protein YP_005108667.1 651120 D 1112912 CDS YP_005108668.1 376278635 11686813 651858..653216 1 NC_016775.1 similar to GP:15075528; identified by sequence similarity; putative; aldehyde dehydrogenase family protein 653216 11686813 BSVBI22_B0665 Brucella suis VBI22 aldehyde dehydrogenase family protein YP_005108668.1 651858 D 1112912 CDS YP_005108669.1 376278636 11686814 653525..653635 1 NC_016775.1 hypothetical protein 653635 11686814 BSVBI22_B0666 Brucella suis VBI22 hypothetical protein YP_005108669.1 653525 D 1112912 CDS YP_005108670.1 376278637 11686815 653694..654641 1 NC_016775.1 similar to GP:15157658, and SP:P15028; identified by sequence similarity; putative; iron compound ABC transporter, periplasmic iron compound-binding protein 654641 11686815 BSVBI22_B0667 Brucella suis VBI22 iron compound ABC transporter, periplasmic iron compound-binding protein YP_005108670.1 653694 D 1112912 CDS YP_005108671.1 376278638 11686816 654698..655660 1 NC_016775.1 similar to GP:15157659, and SP:P37738; identified by sequence similarity; putative; iron compound ABC transporter, permease protein 655660 11686816 BSVBI22_B0668 Brucella suis VBI22 iron compound ABC transporter, permease protein YP_005108671.1 654698 D 1112912 CDS YP_005108672.1 376278639 11686817 655653..656606 1 NC_016775.1 similar to GP:15157660, and SP:P37737; identified by sequence similarity; putative; iron compound ABC transporter, permease protein 656606 11686817 BSVBI22_B0669 Brucella suis VBI22 iron compound ABC transporter, permease protein YP_005108672.1 655653 D 1112912 CDS YP_005108673.1 376278640 11686818 656603..657361 1 NC_016775.1 similar to GP:15157661, and GP:15023678; identified by sequence similarity; putative; iron compound ABC transporter, ATP-binding protein 657361 11686818 BSVBI22_B0670 Brucella suis VBI22 iron compound ABC transporter, ATP-binding protein YP_005108673.1 656603 D 1112912 CDS YP_005108674.1 376278641 11686819 complement(657414..658013) 1 NC_016775.1 similar to GP:14023727; identified by sequence similarity; putative; hypothetical protein 658013 11686819 BSVBI22_B0671 Brucella suis VBI22 hypothetical protein YP_005108674.1 657414 R 1112912 CDS YP_005108675.1 376278642 11686820 658044..658139 1 NC_016775.1 hypothetical protein 658139 11686820 BSVBI22_B0672 Brucella suis VBI22 hypothetical protein YP_005108675.1 658044 D 1112912 CDS YP_005108676.1 376278643 11686821 658151..661747 1 NC_016775.1 similar to GP:15139898; identified by sequence similarity; putative; hydantoinase/oxoprolinase family protein 661747 11686821 BSVBI22_B0673 Brucella suis VBI22 hydantoinase/oxoprolinase family protein YP_005108676.1 658151 D 1112912 CDS YP_005108677.1 376278644 11686822 662033..662806 1 NC_016775.1 similar to GP:15076300; identified by sequence similarity; putative; amino acid ABC transporter, periplasmic amino acid-binding protein 662806 fliY 11686822 fliY Brucella suis VBI22 amino acid ABC transporter, periplasmic amino acid-binding protein YP_005108677.1 662033 D 1112912 CDS YP_005108678.1 376278645 11686823 662986..663666 1 NC_016775.1 similar to GP:15076302; identified by sequence similarity; putative; amino acid ABC transporter, permease protein 663666 11686823 BSVBI22_B0675 Brucella suis VBI22 amino acid ABC transporter, permease protein YP_005108678.1 662986 D 1112912 CDS YP_005108679.1 376278646 11686824 663663..664424 1 NC_016775.1 similar to GP:15076303, GB:J00128, GB:M58569, GB:M64982, GB:J00127, GB:K02272, GB:M26878, SP:P02671, GB:S82092, PID:182407, PID:182424, PID:182426, PID:182428, PID:458554, PID:458555, GB:J00128, GB:M58569, GB:M64982, GB:J00127, GB:K02272, GB:M26878, SP:P02671, GB:S82092, PID:182407, PID:182424, PID:182426, PID:182428, PID:458554, PID:458555, GB:J00128, GB:M58569, GB:M64982, GB:J00127, GB:K02272, GB:M26878, SP:P02671, GB:S82092, PID:182407, PID:182424, PID:182426, PID:182428, PID:458554, and PID:458555; identified by sequence similarity; putative; amino acid ABC transporter, ATP-binding protein 664424 11686824 BSVBI22_B0676 Brucella suis VBI22 amino acid ABC transporter, ATP-binding protein YP_005108679.1 663663 D 1112912 CDS YP_005108680.1 376278647 11686825 664666..666162 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01622; Ppx/GppA family phosphatase 666162 11686825 BSVBI22_B0677 Brucella suis VBI22 Ppx/GppA family phosphatase YP_005108680.1 664666 D 1112912 CDS YP_005108681.1 376278648 11686826 666239..666886 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00438; ribosomal RNA large subunit methyltransferase J, putative 666886 11686826 BSVBI22_B0678 Brucella suis VBI22 ribosomal RNA large subunit methyltransferase J, putative YP_005108681.1 666239 D 1112912 CDS YP_005108682.1 376278649 11686827 complement(667085..668494) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00897; Bcr/CflA subfamily drug resistance transporter 668494 11686827 BSVBI22_B0679 Brucella suis VBI22 Bcr/CflA subfamily drug resistance transporter YP_005108682.1 667085 R 1112912 CDS YP_005108683.1 376278650 11686828 complement(668538..668822) 1 NC_016775.1 hypothetical protein 668822 11686828 BSVBI22_B0680 Brucella suis VBI22 hypothetical protein YP_005108683.1 668538 R 1112912 CDS YP_005108684.1 376278651 11686829 668834..668935 1 NC_016775.1 hypothetical protein 668935 11686829 BSVBI22_B0681 Brucella suis VBI22 hypothetical protein YP_005108684.1 668834 D 1112912 CDS YP_005108685.1 376278652 11686831 complement(670189..671070) 1 NC_016775.1 similar to GP:15076325; identified by sequence similarity; putative; sugar ABC transporter, permease protein, putative 671070 11686831 BSVBI22_B0683 Brucella suis VBI22 sugar ABC transporter, permease protein, putative YP_005108685.1 670189 R 1112912 CDS YP_005108686.1 376278653 11686832 complement(671067..672116) 1 NC_016775.1 similar to GP:13936895, and GP:2828821; identified by sequence similarity; putative; sugar ABC transporter, permease protein, putative 672116 11686832 BSVBI22_B0684 Brucella suis VBI22 sugar ABC transporter, permease protein, putative YP_005108686.1 671067 R 1112912 CDS YP_005108687.1 376278654 11686833 complement(672224..673489) 1 NC_016775.1 similar to GP:9964068, GB:L19113, SP:P39143, PID:437318, and GB:AL009126; identified by sequence similarity; putative; sugar ABC transporter, periplasmic sugar-binding protein 673489 11686833 BSVBI22_B0685 Brucella suis VBI22 sugar ABC transporter, periplasmic sugar-binding protein YP_005108687.1 672224 R 1112912 CDS YP_005108688.1 376278655 11686834 complement(673984..674232) 1 NC_016775.1 hypothetical protein 674232 11686834 BSVBI22_B0686 Brucella suis VBI22 hypothetical protein YP_005108688.1 673984 R 1112912 CDS YP_005108689.1 376278656 11686835 674376..674852 1 NC_016775.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; riboflavin synthase subunit beta 674852 ribH 11686835 ribH Brucella suis VBI22 riboflavin synthase subunit beta YP_005108689.1 674376 D 1112912 CDS YP_005108690.1 376278657 11686837 675771..676115 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01244; hypothetical protein 676115 11686837 BSVBI22_B0689 Brucella suis VBI22 hypothetical protein YP_005108690.1 675771 D 1112912 CDS YP_005108691.1 376278658 11686838 complement(676082..676318) 1 NC_016775.1 hypothetical protein 676318 11686838 BSVBI22_B0690 Brucella suis VBI22 hypothetical protein YP_005108691.1 676082 R 1112912 CDS YP_005108692.1 376278659 11686839 complement(676764..678533) 1 NC_016775.1 similar to GP:15155325, and SP:P71338; identified by sequence similarity; putative; iron compound ABC transporter, permease protein, putative 678533 11686839 BSVBI22_B0691 Brucella suis VBI22 iron compound ABC transporter, permease protein, putative YP_005108692.1 676764 R 1112912 CDS YP_005108693.1 376278660 11686840 complement(678554..679570) 1 NC_016775.1 similar to GP:15155324, and SP:P35755; identified by sequence similarity; putative; iron compound ABC transporter, periplasmic iron compound-binding protein, putative 679570 11686840 BSVBI22_B0692 Brucella suis VBI22 iron compound ABC transporter, periplasmic iron compound-binding protein, putative YP_005108693.1 678554 R 1112912 CDS YP_005108694.1 376278661 11686841 complement(679696..680799) 1 NC_016775.1 similar to GP:15155323; identified by sequence similarity; putative; iron compound ABC transporter, ATP-binding protein, putative 680799 11686841 BSVBI22_B0693 Brucella suis VBI22 iron compound ABC transporter, ATP-binding protein, putative YP_005108694.1 679696 R 1112912 CDS YP_005108695.1 376278662 11686842 681036..682364 1 NC_016775.1 similar to GP:15075956; identified by sequence similarity; putative; D-amino acid oxidase family protein 682364 11686842 BSVBI22_B0694 Brucella suis VBI22 D-amino acid oxidase family protein YP_005108695.1 681036 D 1112912 CDS YP_005108696.1 376278663 11686843 complement(682622..683143) 1 NC_016775.1 similar to GB:M92844, GB:M63625, GB:M92843, SP:P26651, PID:183443, PID:183445, PID:340013, SP:P20922, and PID:581487; identified by sequence similarity; putative; superoxide dismutase, Cu-Zn 683143 sodC 11686843 sodC Brucella suis VBI22 superoxide dismutase, Cu-Zn YP_005108696.1 682622 R 1112912 CDS YP_005108697.1 376278664 11686844 complement(683419..685023) 1 NC_016775.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 685023 11686844 BSVBI22_B0696 Brucella suis VBI22 multicopper oxidase YP_005108697.1 683419 R 1112912 CDS YP_005108698.1 376278665 11686845 complement(685083..685478) 1 NC_016775.1 hypothetical protein 685478 11686845 BSVBI22_B0697 Brucella suis VBI22 hypothetical protein YP_005108698.1 685083 R 1112912 CDS YP_005108699.1 376278666 11686846 685732..687012 1 NC_016775.1 similar to GP:15075195; identified by sequence similarity; putative; major facilitator family transporter 687012 11686846 BSVBI22_B0698 Brucella suis VBI22 major facilitator family transporter YP_005108699.1 685732 D 1112912 CDS YP_005108700.1 376278667 11686847 complement(687090..687617) 1 NC_016775.1 similar to GP:12620484; identified by sequence similarity; putative; alkyl hydroperoxide reductase D 687617 ahpD 11686847 ahpD Brucella suis VBI22 alkyl hydroperoxide reductase D YP_005108700.1 687090 R 1112912 CDS YP_005108701.1 376278668 11686848 complement(687697..688251) 1 NC_016775.1 similar to GP:12620485, and GP:12620485; identified by sequence similarity; putative; alkyl hydroperoxide reductase C 688251 ahpC 11686848 ahpC Brucella suis VBI22 alkyl hydroperoxide reductase C YP_005108701.1 687697 R 1112912 CDS YP_005108702.1 376278669 11686849 688377..689282 1 NC_016775.1 similar to GB:L04510, SP:P36406, and PID:292070; identified by sequence similarity; putative; transcriptional regulator OxyR, putative 689282 11686849 BSVBI22_B0701 Brucella suis VBI22 transcriptional regulator OxyR, putative YP_005108702.1 688377 D 1112912 CDS YP_005108703.1 376278670 11686850 complement(689312..690379) 1 NC_016775.1 similar to GP:15159268, SP:P07002, GB:X66086, PID:42457, GB:U00096, PID:1742636, PID:1742642, PID:1742653, and PID:1787886; identified by sequence similarity; putative; hypothetical protein 690379 11686850 BSVBI22_B0702 Brucella suis VBI22 hypothetical protein YP_005108703.1 689312 R 1112912 CDS YP_005108704.1 376278671 11686851 complement(690477..691469) 1 NC_016775.1 similar to GP:15159273, and SP:O68965; identified by sequence similarity; putative; myo-inositol 2-dehydrogenase 691469 idhA 11686851 idhA Brucella suis VBI22 myo-inositol 2-dehydrogenase YP_005108704.1 690477 R 1112912 CDS YP_005108705.1 376278672 11686852 691703..692473 1 NC_016775.1 similar to GP:15158705; identified by sequence similarity; putative; SIS domain-containing protein 692473 11686852 BSVBI22_B0704 Brucella suis VBI22 SIS domain-containing protein YP_005108705.1 691703 D 1112912 CDS YP_005108706.1 376278673 11686854 694501..696324 1 NC_016775.1 similar to GP:15158707, and GP:7209271; identified by sequence similarity; putative; TPP-requiring enzyme IolD 696324 iolD 11686854 iolD Brucella suis VBI22 TPP-requiring enzyme IolD YP_005108706.1 694501 D 1112912 CDS YP_005108707.1 376278674 11686855 696328..697230 1 NC_016775.1 similar to GP:15158708; identified by sequence similarity; putative; sugar phosphate isomerase/epimerase IolE 697230 iolE 11686855 iolE Brucella suis VBI22 sugar phosphate isomerase/epimerase IolE YP_005108707.1 696328 D 1112912 CDS YP_005108708.1 376278675 11686857 complement(698076..698876) 1 NC_016775.1 similar to GP:15140221, GB:X56692, GB:M11725, GB:M11880, GB:M35163, SP:P02741, PID:181066, PID:181068, PID:181073, and PID:30213; identified by sequence similarity; putative; inositol monophosphatase family protein 698876 11686857 BSVBI22_B0709 Brucella suis VBI22 inositol monophosphatase family protein YP_005108708.1 698076 R 1112912 CDS YP_005108709.1 376278676 11686858 complement(698897..699958) 1 NC_016775.1 similar to GP:15140222; identified by sequence similarity; putative; ABC transporter, ATP-binding protein 699958 11686858 BSVBI22_B0710 Brucella suis VBI22 ABC transporter, ATP-binding protein YP_005108709.1 698897 R 1112912 CDS YP_005108710.1 376278677 11686859 complement(699955..702180) 1 NC_016775.1 similar to GP:15158391, and GP:17743296; identified by sequence similarity; putative; ABC transporter, permease protein 702180 11686859 BSVBI22_B0711 Brucella suis VBI22 ABC transporter, permease protein YP_005108710.1 699955 R 1112912 CDS YP_005108711.1 376278678 11686860 complement(702315..703340) 1 NC_016775.1 similar to GP:15140224; identified by sequence similarity; putative; ABC transporter, periplasmic substrate-binding protein 703340 11686860 BSVBI22_B0712 Brucella suis VBI22 ABC transporter, periplasmic substrate-binding protein YP_005108711.1 702315 R 1112912 CDS YP_005108712.1 376278679 11686861 703324..703467 1 NC_016775.1 hypothetical protein 703467 11686861 BSVBI22_B0713 Brucella suis VBI22 hypothetical protein YP_005108712.1 703324 D 1112912 CDS YP_005108713.1 376278680 11686862 complement(703570..707253) 1 NC_016775.1 proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase 707253 putA 11686862 putA Brucella suis VBI22 proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase YP_005108713.1 703570 R 1112912 CDS YP_005108714.1 376278681 11686863 707416..707910 1 NC_016775.1 similar to GB:M64551, SP:P26514, PID:153527, GB:M64551, SP:P26514, and PID:153527; identified by sequence similarity; putative; proline dehydrogenase transcriptional activator 707910 11686863 BSVBI22_B0715 Brucella suis VBI22 proline dehydrogenase transcriptional activator YP_005108714.1 707416 D 1112912 CDS YP_005108715.1 376278682 11686864 complement(707892..708005) 1 NC_016775.1 hypothetical protein 708005 11686864 BSVBI22_B0716 Brucella suis VBI22 hypothetical protein YP_005108715.1 707892 R 1112912 CDS YP_005108716.1 376278683 11686865 complement(708941..711739) 1 NC_016775.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 711739 gcvP 11686865 gcvP Brucella suis VBI22 glycine dehydrogenase YP_005108716.1 708941 R 1112912 CDS YP_005108717.1 376278684 11686866 complement(711744..712112) 1 NC_016775.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 712112 gcvH 11686866 gcvH Brucella suis VBI22 glycine cleavage system protein H YP_005108717.1 711744 R 1112912 CDS YP_005108718.1 376278685 11686867 complement(712118..713221) 1 NC_016775.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 713221 gcvT 11686867 gcvT Brucella suis VBI22 glycine cleavage system aminomethyltransferase T YP_005108718.1 712118 R 1112912 CDS YP_005108719.1 376278686 11686868 713863..714021 1 NC_016775.1 similar to GP:15074478; identified by sequence similarity; putative; hypothetical protein 714021 11686868 BSVBI22_B0720 Brucella suis VBI22 hypothetical protein YP_005108719.1 713863 D 1112912 CDS YP_005108720.1 376278687 11686869 complement(714203..715432) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01424; pyridine nucleotide-disulfide oxidoreductase family protein 715432 11686869 BSVBI22_B0721 Brucella suis VBI22 pyridine nucleotide-disulfide oxidoreductase family protein YP_005108720.1 714203 R 1112912 CDS YP_005108721.1 376278688 11686870 complement(715544..716488) 1 NC_016775.1 similar to GP:15024826; identified by sequence similarity; putative; transcriptional regulator, putative 716488 11686870 BSVBI22_B0722 Brucella suis VBI22 transcriptional regulator, putative YP_005108721.1 715544 R 1112912 CDS YP_005108722.1 376278689 11686871 716515..717312 1 NC_016775.1 hypothetical protein 717312 11686871 BSVBI22_B0723 Brucella suis VBI22 hypothetical protein YP_005108722.1 716515 D 1112912 CDS YP_005108723.1 376278690 11686872 717376..718743 1 NC_016775.1 identified by match to PFAM protein family HMM PF00120; glutamine synthetase family protein 718743 11686872 BSVBI22_B0724 Brucella suis VBI22 glutamine synthetase family protein YP_005108723.1 717376 D 1112912 CDS YP_005108724.1 376278691 11686873 complement(718737..718853) 1 NC_016775.1 hypothetical protein 718853 11686873 BSVBI22_B0725 Brucella suis VBI22 hypothetical protein YP_005108724.1 718737 R 1112912 CDS YP_005108725.1 376278692 11686874 718844..720013 1 NC_016775.1 similar to GB:M33308, SP:P18206, PID:292902, and PID:340237; identified by sequence similarity; putative; alcohol dehydrogenase, iron-containing 720013 11686874 BSVBI22_B0726 Brucella suis VBI22 alcohol dehydrogenase, iron-containing YP_005108725.1 718844 D 1112912 CDS YP_005108726.1 376278693 11686875 720195..720638 1 NC_016775.1 similar to GP:3236220, and GP:3236220; identified by sequence similarity; putative; immunoreactive 14 kDa protein BA14k 720638 11686875 BSVBI22_B0727 Brucella suis VBI22 immunoreactive 14 kDa protein BA14k YP_005108726.1 720195 D 1112912 CDS YP_005108727.1 376278694 11686876 720768..720965 1 NC_016775.1 hypothetical protein 720965 11686876 BSVBI22_B0728 Brucella suis VBI22 hypothetical protein YP_005108727.1 720768 D 1112912 CDS YP_005108728.1 376278695 11686877 721101..721946 1 NC_016775.1 similar to GP:15075527; identified by sequence similarity; putative; hypothetical protein 721946 11686877 BSVBI22_B0729 Brucella suis VBI22 hypothetical protein YP_005108728.1 721101 D 1112912 CDS YP_005108729.1 376278696 11686878 complement(721992..722858) 1 NC_016775.1 similar to GP:19747452; identified by sequence similarity; putative; glycine betaine/L-proline ABC transporter, periplasmic glycine betaine-binding protein, putative 722858 11686878 BSVBI22_B0730 Brucella suis VBI22 glycine betaine/L-proline ABC transporter, periplasmic glycine betaine-binding protein, putative YP_005108729.1 721992 R 1112912 CDS YP_005108730.1 376278697 11686879 complement(722912..723817) 1 NC_016775.1 similar to GP:6119662, and GP:6119854; identified by sequence similarity; putative; glycine betaine/L-proline ABC transporter, permease protein, putative 723817 11686879 BSVBI22_B0731 Brucella suis VBI22 glycine betaine/L-proline ABC transporter, permease protein, putative YP_005108730.1 722912 R 1112912 CDS YP_005108731.1 376278698 11686880 complement(723880..725046) 1 NC_016775.1 similar to SP:P46920, GB:M88282, SP:P40200, and PID:338672; identified by sequence similarity; putative; glycine betaine/L-proline ABC transporter, ATP-binding protein 725046 11686880 BSVBI22_B0732 Brucella suis VBI22 glycine betaine/L-proline ABC transporter, ATP-binding protein YP_005108731.1 723880 R 1112912 CDS YP_005108732.1 376278699 11686881 complement(725259..725444) 1 NC_016775.1 hypothetical protein 725444 11686881 BSVBI22_B0733 Brucella suis VBI22 hypothetical protein YP_005108732.1 725259 R 1112912 CDS YP_005108733.1 376278700 11686882 complement(725607..726080) 1 NC_016775.1 hypothetical protein 726080 11686882 BSVBI22_B0734 Brucella suis VBI22 hypothetical protein YP_005108733.1 725607 R 1112912 CDS YP_005108734.1 376278701 11686883 complement(726094..727161) 1 NC_016775.1 similar to GP:15140598; identified by sequence similarity; putative; amino acid processing enzyme-related protein 727161 11686883 BSVBI22_B0735 Brucella suis VBI22 amino acid processing enzyme-related protein YP_005108734.1 726094 R 1112912 CDS YP_005108735.1 376278702 11686884 complement(727166..728083) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00441; RpiR family transcriptional regulator 728083 11686884 BSVBI22_B0736 Brucella suis VBI22 RpiR family transcriptional regulator YP_005108735.1 727166 R 1112912 CDS YP_005108736.1 376278703 11686885 complement(728055..729107) 1 NC_016775.1 similar to SP:P55604; identified by sequence similarity; putative; sugar ABC transporter, ATP-binding protein, putative 729107 11686885 BSVBI22_B0737 Brucella suis VBI22 sugar ABC transporter, ATP-binding protein, putative YP_005108736.1 728055 R 1112912 CDS YP_005108737.1 376278704 11686886 complement(729112..729885) 1 NC_016775.1 similar to GP:14024269; identified by sequence similarity; putative; short chain dehydrogenase/reductase family oxidoreductase 729885 11686886 BSVBI22_B0738 Brucella suis VBI22 short chain dehydrogenase/reductase family oxidoreductase YP_005108737.1 729112 R 1112912 CDS YP_005108738.1 376278705 11686887 729902..730012 1 NC_016775.1 hypothetical protein 730012 11686887 BSVBI22_B0739 Brucella suis VBI22 hypothetical protein YP_005108738.1 729902 D 1112912 CDS YP_005108739.1 376278706 11686888 730065..731300 1 NC_016775.1 similar to GP:2828820; identified by sequence similarity; putative; sugar ABC transporter, periplasmic sugar-binding protein, putative 731300 11686888 BSVBI22_B0740 Brucella suis VBI22 sugar ABC transporter, periplasmic sugar-binding protein, putative YP_005108739.1 730065 D 1112912 CDS YP_005108740.1 376278707 11686889 731373..732242 1 NC_016775.1 similar to GP:2828821; identified by sequence similarity; putative; sugar ABC transporter, permease protein, putative 732242 11686889 BSVBI22_B0741 Brucella suis VBI22 sugar ABC transporter, permease protein, putative YP_005108740.1 731373 D 1112912 CDS YP_005108741.1 376278708 11686890 732239..733066 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00969; sugar ABC transporter, permease protein, putative 733066 11686890 BSVBI22_B0742 Brucella suis VBI22 sugar ABC transporter, permease protein, putative YP_005108741.1 732239 D 1112912 CDS YP_005108742.1 376278709 11686891 733079..733450 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00004; endoribonuclease L-PSP, putative 733450 11686891 BSVBI22_B0743 Brucella suis VBI22 endoribonuclease L-PSP, putative YP_005108742.1 733079 D 1112912 CDS YP_005108743.1 376278710 11686892 733477..734946 1 NC_016775.1 hypothetical protein 734946 11686892 BSVBI22_B0744 Brucella suis VBI22 hypothetical protein YP_005108743.1 733477 D 1112912 CDS YP_005108744.1 376278711 11686893 complement(735107..735349) 1 NC_016775.1 hypothetical protein 735349 11686893 BSVBI22_B0745 Brucella suis VBI22 hypothetical protein YP_005108744.1 735107 R 1112912 CDS YP_005108745.1 376278712 11686894 complement(735407..736204) 1 NC_016775.1 similar to GP:15139930, and GP:8217385; identified by sequence similarity; putative; iron compound ABC transporter, ATP-binding protein 736204 11686894 BSVBI22_B0746 Brucella suis VBI22 iron compound ABC transporter, ATP-binding protein YP_005108745.1 735407 R 1112912 CDS YP_005108746.1 376278713 11686895 complement(736201..737244) 1 NC_016775.1 similar to GP:15139929; identified by sequence similarity; putative; iron compound ABC transporter, permease protein 737244 11686895 BSVBI22_B0747 Brucella suis VBI22 iron compound ABC transporter, permease protein YP_005108746.1 736201 R 1112912 CDS YP_005108747.1 376278714 11686896 complement(737241..738275) 1 NC_016775.1 similar to GP:15159961, and GP:8546929; identified by sequence similarity; putative; iron compound ABC transporter, periplasmic iron compound-binding protein 738275 11686896 BSVBI22_B0748 Brucella suis VBI22 iron compound ABC transporter, periplasmic iron compound-binding protein YP_005108747.1 737241 R 1112912 CDS YP_005108748.1 376278715 11686897 complement(738232..738648) 1 NC_016775.1 hypothetical protein 738648 11686897 BSVBI22_B0749 Brucella suis VBI22 hypothetical protein YP_005108748.1 738232 R 1112912 CDS YP_005108749.1 376278716 11686898 complement(738826..739692) 1 NC_016775.1 similar to GP:15162366; identified by sequence similarity; putative; HlyD family secretion protein 739692 11686898 BSVBI22_B0750 Brucella suis VBI22 HlyD family secretion protein YP_005108749.1 738826 R 1112912 CDS YP_005108750.1 376278717 11686899 complement(739689..739898) 1 NC_016775.1 similar to GB:M23114, GB:M23116, GB:M23278, GB:M23115, SP:P16614, SP:P16615, PID:306850, PID:306851, PID:567108, GB:M23114, GB:M23116, GB:M23278, GB:M23115, SP:P16614, SP:P16615, PID:306850, PID:306851, and PID:567108; identified by sequence similarity; putative; hypothetical protein 739898 11686899 BSVBI22_B0751 Brucella suis VBI22 hypothetical protein YP_005108750.1 739689 R 1112912 CDS YP_005108751.1 376278718 11686900 complement(739925..742021) 1 NC_016775.1 similar to GP:15162367; identified by sequence similarity; putative; hypothetical protein 742021 11686900 BSVBI22_B0752 Brucella suis VBI22 hypothetical protein YP_005108751.1 739925 R 1112912 CDS YP_005108752.1 376278719 11686901 complement(742064..742501) 1 NC_016775.1 similar to GP:15074064; identified by sequence similarity; putative; MarR family transcriptional regulator 742501 11686901 BSVBI22_B0753 Brucella suis VBI22 MarR family transcriptional regulator YP_005108752.1 742064 R 1112912 CDS YP_005108753.1 376278720 11686902 742751..743497 1 NC_016775.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 743497 11686902 BSVBI22_B0754 Brucella suis VBI22 16S ribosomal RNA methyltransferase RsmE YP_005108753.1 742751 D 1112912 CDS YP_005108754.1 376278721 11686903 743597..744970 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01436; glutamate--cysteine ligase 744970 11686903 BSVBI22_B0755 Brucella suis VBI22 glutamate--cysteine ligase YP_005108754.1 743597 D 1112912 CDS YP_005108755.1 376278722 11686904 complement(745036..746571) 1 NC_016775.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 746571 xseA 11686904 xseA Brucella suis VBI22 exodeoxyribonuclease VII large subunit YP_005108755.1 745036 R 1112912 CDS YP_005108756.1 376278723 11686905 complement(746640..747608) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00126; LysR family transcriptional regulator 747608 11686905 BSVBI22_B0757 Brucella suis VBI22 LysR family transcriptional regulator YP_005108756.1 746640 R 1112912 CDS YP_005108757.1 376278724 11686906 747775..748077 1 NC_016775.1 hypothetical protein 748077 11686906 BSVBI22_B0758 Brucella suis VBI22 hypothetical protein YP_005108757.1 747775 D 1112912 CDS YP_005108758.1 376278725 11686907 748071..748325 1 NC_016775.1 hypothetical protein 748325 11686907 BSVBI22_B0759 Brucella suis VBI22 hypothetical protein YP_005108758.1 748071 D 1112912 CDS YP_005108759.1 376278726 11686908 748329..749759 1 NC_016775.1 identified by match to PFAM protein family HMM PF00120; glutamine synthetase family protein 749759 11686908 BSVBI22_B0760 Brucella suis VBI22 glutamine synthetase family protein YP_005108759.1 748329 D 1112912 CDS YP_005108760.1 376278727 11686909 749819..750181 1 NC_016775.1 crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown; hypothetical protein 750181 11686909 BSVBI22_B0761 Brucella suis VBI22 hypothetical protein YP_005108760.1 749819 D 1112912 CDS YP_005108761.1 376278728 11686910 750235..751521 1 NC_016775.1 similar to SP:Q9Z3S3; identified by sequence similarity; putative; D-amino acid oxidase family protein 751521 11686910 BSVBI22_B0762 Brucella suis VBI22 D-amino acid oxidase family protein YP_005108761.1 750235 D 1112912 CDS YP_005108762.1 376278729 11686911 complement(751532..751948) 1 NC_016775.1 identified by match to PFAM protein family HMM PF01047; MarR family transcriptional regulator 751948 11686911 BSVBI22_B0763 Brucella suis VBI22 MarR family transcriptional regulator YP_005108762.1 751532 R 1112912 CDS YP_005108763.1 376278730 11686912 complement(752258..753058) 1 NC_016775.1 hypothetical protein 753058 11686912 BSVBI22_B0764 Brucella suis VBI22 hypothetical protein YP_005108763.1 752258 R 1112912 CDS YP_005108764.1 376278731 11686913 complement(753317..753781) 1 NC_016775.1 identified by match to PFAM protein family HMM PF01037; AsnC family transcriptional regulator 753781 11686913 BSVBI22_B0765 Brucella suis VBI22 AsnC family transcriptional regulator YP_005108764.1 753317 R 1112912 CDS YP_005108765.1 376278732 11686914 754157..754897 1 NC_016775.1 similar to SP:O07942; identified by sequence similarity; putative; AzlC family protein 754897 11686914 BSVBI22_B0766 Brucella suis VBI22 AzlC family protein YP_005108765.1 754157 D 1112912 CDS YP_005108766.1 376278733 11686915 754894..755193 1 NC_016775.1 hypothetical protein 755193 11686915 BSVBI22_B0767 Brucella suis VBI22 hypothetical protein YP_005108766.1 754894 D 1112912 CDS YP_005108767.1 376278734 11686917 complement(756768..757517) 1 NC_016775.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 757517 fabG 11686917 fabG Brucella suis VBI22 3-ketoacyl-(acyl-carrier-protein) reductase YP_005108767.1 756768 R 1112912 CDS YP_005108768.1 376278735 11686918 757788..759263 1 NC_016775.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 759263 zwf 11686918 zwf Brucella suis VBI22 glucose-6-phosphate 1-dehydrogenase YP_005108768.1 757788 D 1112912 CDS YP_005108769.1 376278736 11686919 759392..760090 1 NC_016775.1 catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone; 6-phosphogluconolactonase 760090 pgl 11686919 pgl Brucella suis VBI22 6-phosphogluconolactonase YP_005108769.1 759392 D 1112912 CDS YP_005108770.1 376278737 11686921 complement(762042..762941) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00763; FolD bifunctional protein 762941 folD 11686921 folD Brucella suis VBI22 FolD bifunctional protein YP_005108770.1 762042 R 1112912 CDS YP_005108771.1 376278738 11686922 763262..764077 1 NC_016775.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 764077 proC 11686922 proC Brucella suis VBI22 pyrroline-5-carboxylate reductase YP_005108771.1 763262 D 1112912 CDS YP_005108772.1 376278739 11686924 complement(765665..766495) 1 NC_016775.1 similar to SP:Q53192; identified by sequence similarity; putative; peptide ABC transporter, permease protein 766495 11686924 BSVBI22_B0776 Brucella suis VBI22 peptide ABC transporter, permease protein YP_005108772.1 765665 R 1112912 CDS YP_005108773.1 376278740 11686925 complement(766492..767490) 1 NC_016775.1 similar to SP:Q53191; identified by sequence similarity; putative; peptide ABC transporter, permease protein 767490 11686925 BSVBI22_B0777 Brucella suis VBI22 peptide ABC transporter, permease protein YP_005108773.1 766492 R 1112912 CDS YP_005108774.1 376278741 11686926 complement(767508..769121) 1 NC_016775.1 similar to GP:17741829; identified by sequence similarity; putative; peptide ABC transporter, periplasmic peptide-binding protein, putative 769121 11686926 BSVBI22_B0778 Brucella suis VBI22 peptide ABC transporter, periplasmic peptide-binding protein, putative YP_005108774.1 767508 R 1112912 CDS YP_005108775.1 376278742 11686927 769476..769820 1 NC_016775.1 similar to GP:15141400, and GP:15141400; identified by sequence similarity; putative; hypothetical protein 769820 11686927 BSVBI22_B0779 Brucella suis VBI22 hypothetical protein YP_005108775.1 769476 D 1112912 CDS YP_005108776.1 376278743 11686928 769969..770628 1 NC_016775.1 similar to GP:14277936; identified by sequence similarity; putative; carbonic anhydrase 770628 11686928 BSVBI22_B0780 Brucella suis VBI22 carbonic anhydrase YP_005108776.1 769969 D 1112912 CDS YP_005108777.1 376278744 11686929 complement(770690..771100) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03794; hypothetical protein 771100 11686929 BSVBI22_B0781 Brucella suis VBI22 hypothetical protein YP_005108777.1 770690 R 1112912 CDS YP_005108778.1 376278745 11686930 771295..772950 1 NC_016775.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 772950 lysK 11686930 lysK Brucella suis VBI22 lysyl-tRNA synthetase YP_005108778.1 771295 D 1112912 CDS YP_005108779.1 376278746 11686931 complement(773038..773997) 1 NC_016775.1 similar to GP:14025443; identified by sequence similarity; putative; hypothetical protein 773997 11686931 BSVBI22_B0783 Brucella suis VBI22 hypothetical protein YP_005108779.1 773038 R 1112912 CDS YP_005108780.1 376278747 11686932 complement(773998..774654) 1 NC_016775.1 similar to GP:15155410; identified by sequence similarity; putative; S24 family peptidase 774654 11686932 BSVBI22_B0784 Brucella suis VBI22 S24 family peptidase YP_005108780.1 773998 R 1112912 CDS YP_005108781.1 376278748 11686933 complement(774892..777108) 1 NC_016775.1 similar to GB:X65488, SP:Q00839, PID:32358, and PID:532037; identified by sequence similarity; putative; fatty oxidation complex, alpha subunit 777108 fadB 11686933 fadB Brucella suis VBI22 fatty oxidation complex, alpha subunit YP_005108781.1 774892 R 1112912 CDS YP_005108782.1 376278749 11686934 complement(777124..778332) 1 NC_016775.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 778332 11686934 BSVBI22_B0786 Brucella suis VBI22 acetyl-CoA acetyltransferase YP_005108782.1 777124 R 1112912 CDS YP_005108783.1 376278750 11686935 complement(778397..780190) 1 NC_016775.1 identified by match to PFAM protein family HMM PF02771; acyl-CoA dehydrogenase family protein 780190 11686935 BSVBI22_B0787 Brucella suis VBI22 acyl-CoA dehydrogenase family protein YP_005108783.1 778397 R 1112912 CDS YP_005108784.1 376278751 11686936 complement(780165..780359) 1 NC_016775.1 hypothetical protein 780359 11686936 BSVBI22_B0788 Brucella suis VBI22 hypothetical protein YP_005108784.1 780165 R 1112912 CDS YP_005108785.1 376278752 11686937 complement(780356..780634) 1 NC_016775.1 hypothetical protein 780634 11686937 BSVBI22_B0789 Brucella suis VBI22 hypothetical protein YP_005108785.1 780356 R 1112912 CDS YP_005108786.1 376278753 11686939 782137..783303 1 NC_016775.1 identified by match to PFAM protein family HMM PF02771; acyl-CoA dehydrogenase family protein 783303 11686939 BSVBI22_B0791 Brucella suis VBI22 acyl-CoA dehydrogenase family protein YP_005108786.1 782137 D 1112912 CDS YP_005108787.1 376278754 11686940 complement(783436..784236) 1 NC_016775.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 784236 nikE 11686940 nikE Brucella suis VBI22 nickel transporter ATP-binding protein NikE YP_005108787.1 783436 R 1112912 CDS YP_005108788.1 376278755 11686941 complement(784233..785021) 1 NC_016775.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 785021 nikD 11686941 nikD Brucella suis VBI22 nickel transporter ATP-binding protein NikD YP_005108788.1 784233 R 1112912 CDS YP_005108789.1 376278756 11686942 complement(785018..785890) 1 NC_016775.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 785890 nikC 11686942 nikC Brucella suis VBI22 nickel transporter permease NikC YP_005108789.1 785018 R 1112912 CDS YP_005108790.1 376278757 11686943 complement(785887..786831) 1 NC_016775.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 786831 nikB 11686943 nikB Brucella suis VBI22 nickel transporter permease NikB YP_005108790.1 785887 R 1112912 CDS YP_005108791.1 376278758 11686944 complement(786833..788413) 1 NC_016775.1 similar to GP:12331180, and GP:12331180; identified by sequence similarity; putative; nickel ABC transporter, nickel-binding protein, putative 788413 11686944 BSVBI22_B0796 Brucella suis VBI22 nickel ABC transporter, nickel-binding protein, putative YP_005108791.1 786833 R 1112912 CDS YP_005108792.1 376278759 11686945 788680..789078 1 NC_016775.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 789078 11686945 BSVBI22_B0797 Brucella suis VBI22 nickel responsive regulator YP_005108792.1 788680 D 1112912 CDS YP_005108793.1 376278760 11686946 complement(789089..790633) 1 NC_016775.1 similar to GP:15158051, GB:M25393, SP:P17706, and PID:804750; identified by sequence similarity; putative; UxaA family hydrolase 790633 11686946 BSVBI22_B0798 Brucella suis VBI22 UxaA family hydrolase YP_005108793.1 789089 R 1112912 CDS YP_005108794.1 376278761 11686947 complement(790711..791553) 1 NC_016775.1 similar to GB:U12770, GB:U12774, GB:U12775, GB:L37019, SP:P42127, PID:540073, and PID:608648; identified by sequence similarity; putative; ABC transporter, permease protein 791553 11686947 BSVBI22_B0799 Brucella suis VBI22 ABC transporter, permease protein YP_005108794.1 790711 R 1112912 CDS YP_005108795.1 376278762 11686949 complement(792461..793513) 1 NC_016775.1 similar to GP:9501758; identified by sequence similarity; putative; ABC transporter, ATP-binding protein 793513 11686949 BSVBI22_B0801 Brucella suis VBI22 ABC transporter, ATP-binding protein YP_005108795.1 792461 R 1112912 CDS YP_005108796.1 376278763 11686950 complement(793591..794772) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01409; ABC transporter, periplasmic substrate-binding protein 794772 11686950 BSVBI22_B0802 Brucella suis VBI22 ABC transporter, periplasmic substrate-binding protein YP_005108796.1 793591 R 1112912 CDS YP_005108797.1 376278764 11686952 complement(796436..797836) 1 NC_016775.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 797836 11686952 BSVBI22_B0804 Brucella suis VBI22 glucuronate isomerase YP_005108797.1 796436 R 1112912 CDS YP_005108798.1 376278765 11686953 798165..798938 1 NC_016775.1 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 798938 11686953 BSVBI22_B0805 Brucella suis VBI22 GntR family transcriptional regulator YP_005108798.1 798165 D 1112912 CDS YP_005108799.1 376278766 11686954 798999..800204 1 NC_016775.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 800204 uxuA 11686954 uxuA Brucella suis VBI22 mannonate dehydratase YP_005108799.1 798999 D 1112912 CDS YP_005108800.1 376278767 11686956 complement(803490..804476) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00998; HlyD family secretion protein 804476 11686956 BSVBI22_B0808 Brucella suis VBI22 HlyD family secretion protein YP_005108800.1 803490 R 1112912 CDS YP_005108801.1 376278768 11686957 804933..805334 1 NC_016775.1 similar to GP:15074323; identified by sequence similarity; putative; crcB family protein 805334 11686957 BSVBI22_B0809 Brucella suis VBI22 crcB family protein YP_005108801.1 804933 D 1112912 CDS YP_005108802.1 376278769 11686958 805331..805744 1 NC_016775.1 similar to GP:15074323; identified by sequence similarity; putative; crcB family protein 805744 11686958 BSVBI22_B0810 Brucella suis VBI22 crcB family protein YP_005108802.1 805331 D 1112912 CDS YP_005108803.1 376278770 11686959 805760..806119 1 NC_016775.1 identified by match to PFAM protein family HMM PF02641; hypothetical protein 806119 11686959 BSVBI22_B0811 Brucella suis VBI22 hypothetical protein YP_005108803.1 805760 D 1112912 CDS YP_005108804.1 376278771 11686960 complement(806174..806569) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator 806569 11686960 BSVBI22_B0812 Brucella suis VBI22 MerR family transcriptional regulator YP_005108804.1 806174 R 1112912 CDS YP_005108805.1 376278772 11686961 complement(806863..807000) 1 NC_016775.1 hypothetical protein 807000 11686961 BSVBI22_B0813 Brucella suis VBI22 hypothetical protein YP_005108805.1 806863 R 1112912 CDS YP_005108806.1 376278773 11685752 806999..809740 1 NC_016775.1 identified by match to PFAM protein family HMM PF04012; peptidoglycan-binding protein, putative 809740 11685752 BSVBI22_B0814 Brucella suis VBI22 peptidoglycan-binding protein, putative YP_005108806.1 806999 D 1112912 CDS YP_005108807.1 376278774 11685753 809977..810927 1 NC_016775.1 similar to GP:14025434, and GP:14025434; identified by sequence similarity; putative; hypothetical protein 810927 11685753 BSVBI22_B0815 Brucella suis VBI22 hypothetical protein YP_005108807.1 809977 D 1112912 CDS YP_005108808.1 376278775 11685754 810962..811753 1 NC_016775.1 hypothetical protein 811753 11685754 BSVBI22_B0816 Brucella suis VBI22 hypothetical protein YP_005108808.1 810962 D 1112912 CDS YP_005108809.1 376278776 11685755 complement(811851..812567) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00024; hypothetical protein 812567 11685755 BSVBI22_B0817 Brucella suis VBI22 hypothetical protein YP_005108809.1 811851 R 1112912 CDS YP_005108810.1 376278777 11685756 complement(812564..815119) 1 NC_016775.1 similar to GP:14025425; identified by sequence similarity; putative; DEAD-box ATP dependent DNA helicase 815119 11685756 BSVBI22_B0818 Brucella suis VBI22 DEAD-box ATP dependent DNA helicase YP_005108810.1 812564 R 1112912 CDS YP_005108811.1 376278778 11685757 complement(815129..815275) 1 NC_016775.1 hypothetical protein 815275 11685757 BSVBI22_B0819 Brucella suis VBI22 hypothetical protein YP_005108811.1 815129 R 1112912 CDS YP_005108812.1 376278779 11685758 complement(815371..816393) 1 NC_016775.1 similar to GP:15073435; identified by sequence similarity; putative; hypothetical protein 816393 11685758 BSVBI22_B0820 Brucella suis VBI22 hypothetical protein YP_005108812.1 815371 R 1112912 CDS YP_005108813.1 376278780 11685759 816371..816508 1 NC_016775.1 hypothetical protein 816508 11685759 BSVBI22_B0821 Brucella suis VBI22 hypothetical protein YP_005108813.1 816371 D 1112912 CDS YP_005108814.1 376278781 11685760 complement(816592..816753) 1 NC_016775.1 hypothetical protein 816753 11685760 BSVBI22_B0822 Brucella suis VBI22 hypothetical protein YP_005108814.1 816592 R 1112912 CDS YP_005108815.1 376278782 11685761 816900..817868 1 NC_016775.1 similar to GP:15155334, and GP:15073434; identified by sequence similarity; putative; 2-nitropropane dioxygenase family protein 817868 11685761 BSVBI22_B0823 Brucella suis VBI22 2-nitropropane dioxygenase family protein YP_005108815.1 816900 D 1112912 CDS YP_005108816.1 376278783 11685762 817927..818064 1 NC_016775.1 hypothetical protein 818064 11685762 BSVBI22_B0824 Brucella suis VBI22 hypothetical protein YP_005108816.1 817927 D 1112912 CDS YP_005108817.1 376278784 11685764 818923..819645 1 NC_016775.1 hypothetical protein 819645 11685764 BSVBI22_B0825 Brucella suis VBI22 hypothetical protein YP_005108817.1 818923 D 1112912 CDS YP_005108818.1 376278785 11685765 complement(819652..820152) 1 NC_016775.1 hypothetical protein 820152 11685765 BSVBI22_B0826 Brucella suis VBI22 hypothetical protein YP_005108818.1 819652 R 1112912 CDS YP_005108819.1 376278786 11685766 820291..820407 1 NC_016775.1 hypothetical protein 820407 11685766 BSVBI22_B0827 Brucella suis VBI22 hypothetical protein YP_005108819.1 820291 D 1112912 CDS YP_005108820.1 376278787 11685767 complement(820703..820900) 1 NC_016775.1 similar to GP:7630140; identified by sequence similarity; putative; hypothetical protein 820900 11685767 BSVBI22_B0828 Brucella suis VBI22 hypothetical protein YP_005108820.1 820703 R 1112912 CDS YP_005108821.1 376278788 11685768 820969..821124 1 NC_016775.1 hypothetical protein 821124 11685768 BSVBI22_B0829 Brucella suis VBI22 hypothetical protein YP_005108821.1 820969 D 1112912 CDS YP_005108822.1 376278789 11685769 complement(821918..822058) 1 NC_016775.1 hypothetical protein 822058 11685769 BSVBI22_B0830 Brucella suis VBI22 hypothetical protein YP_005108822.1 821918 R 1112912 CDS YP_005108823.1 376278790 11685770 822219..822851 1 NC_016775.1 identified by match to PFAM protein family HMM PF01420; hypothetical protein 822851 11685770 BSVBI22_B0831 Brucella suis VBI22 hypothetical protein YP_005108823.1 822219 D 1112912 CDS YP_005108824.1 376278791 11685771 822859..824385 1 NC_016775.1 identified by match to PFAM protein family HMM PF01170; type I restriction-modification system, M subunit 824385 hsdM 11685771 hsdM Brucella suis VBI22 type I restriction-modification system, M subunit YP_005108824.1 822859 D 1112912 CDS YP_005108825.1 376278792 11685772 824375..825598 1 NC_016775.1 identified by match to PFAM protein family HMM PF03809; type I restriction-modification system, S subunit 825598 hsdS 11685772 hsdS Brucella suis VBI22 type I restriction-modification system, S subunit YP_005108825.1 824375 D 1112912 CDS YP_005108826.1 376278793 11685773 825661..828564 1 NC_016775.1 identified by match to PFAM protein family HMM PF03726; type I restriction-modification enzyme, R subunit 828564 hsdR 11685773 hsdR Brucella suis VBI22 type I restriction-modification enzyme, R subunit YP_005108826.1 825661 D 1112912 CDS YP_005108827.1 376278794 11685774 828561..829301 1 NC_016775.1 identified by match to PFAM protein family HMM PF01863; hypothetical protein 829301 11685774 BSVBI22_B0835 Brucella suis VBI22 hypothetical protein YP_005108827.1 828561 D 1112912 CDS YP_005108828.1 376278795 11685775 829309..830238 1 NC_016775.1 similar to GP:6900910, GB:J00153, GB:V00491, GB:V00492, GB:J00157, GB:M22814, SP:P01922, PID:1335076, PID:1340147, PID:1340148, PID:1817577, PID:1817578, PID:183801, PID:183805, PID:28547, PID:28558, PID:386764, PID:386765, PID:537333, GB:J00153, GB:V00516, GB:V00493, GB:V00488, GB:V00489, GB:M24793, GB:M22814, SP:P01922, PID:1335076, PID:1340147, PID:1340148, PID:1817577, PID:1817578, PID:183801, PID:183805, PID:28547, PID:28558, PID:386764, PID:386765, and PID:537333; identified by sequence similarity; putative; hypothetical protein 830238 11685775 BSVBI22_B0836 Brucella suis VBI22 hypothetical protein YP_005108828.1 829309 D 1112912 CDS YP_005108829.1 376278796 11685776 830618..832120 1 NC_016775.1 hypothetical protein 832120 11685776 BSVBI22_B0837 Brucella suis VBI22 hypothetical protein YP_005108829.1 830618 D 1112912 CDS YP_005108830.1 376278797 11685777 832655..832966 1 NC_016775.1 similar to GB:X07282, SP:P10826, PID:184477, PID:32026, PID:35883, GB:D38554, PID:1354931, and PID:559705; identified by sequence similarity; putative; IS711, transposase orfA 832966 11685777 BSVBI22_B0838 Brucella suis VBI22 IS711, transposase orfA YP_005108830.1 832655 D 1112912 CDS YP_005108831.1 376278798 11685778 832998..833390 1 NC_016775.1 similar to PIR:PN0685, GB:X07282, SP:P10826, PID:184477, PID:32026, and PID:35883; identified by sequence similarity; putative; IS711, transposase orfB 833390 11685778 BSVBI22_B0839 Brucella suis VBI22 IS711, transposase orfB YP_005108831.1 832998 D 1112912 CDS YP_005108832.1 376278799 11685779 complement(833404..833538) 1 NC_016775.1 hypothetical protein 833538 11685779 BSVBI22_B0840 Brucella suis VBI22 hypothetical protein YP_005108832.1 833404 R 1112912 CDS YP_005108833.1 376278800 11685780 833800..834246 1 NC_016775.1 hypothetical protein 834246 11685780 BSVBI22_B0841 Brucella suis VBI22 hypothetical protein YP_005108833.1 833800 D 1112912 CDS YP_005108834.1 376278801 11685781 834357..836042 1 NC_016775.1 identified by match to PFAM protein family HMM PF03788; hypothetical protein 836042 11685781 BSVBI22_B0842 Brucella suis VBI22 hypothetical protein YP_005108834.1 834357 D 1112912 CDS YP_005108835.1 376278802 11685782 complement(836206..837660) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03819; aminotransferase, class III 837660 11685782 BSVBI22_B0843 Brucella suis VBI22 aminotransferase, class III YP_005108835.1 836206 R 1112912 CDS YP_005108836.1 376278803 11685783 complement(837671..838681) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01472; epimerase/dehydratase family protein, putative 838681 11685783 BSVBI22_B0844 Brucella suis VBI22 epimerase/dehydratase family protein, putative YP_005108836.1 837671 R 1112912 CDS YP_005108837.1 376278804 11685784 complement(838730..839149) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00893; hypothetical protein 839149 11685784 BSVBI22_B0845 Brucella suis VBI22 hypothetical protein YP_005108837.1 838730 R 1112912 CDS YP_005108838.1 376278805 11685786 complement(840517..841956) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01668; hypothetical protein 841956 11685786 BSVBI22_B0847 Brucella suis VBI22 hypothetical protein YP_005108838.1 840517 R 1112912 CDS YP_005108839.1 376278806 11685787 842192..842287 1 NC_016775.1 hypothetical protein 842287 11685787 BSVBI22_B0848 Brucella suis VBI22 hypothetical protein YP_005108839.1 842192 D 1112912 CDS YP_005108840.1 376278807 11685788 complement(842579..843400) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00455; DeoR family transcriptional regulator 843400 11685788 BSVBI22_B0849 Brucella suis VBI22 DeoR family transcriptional regulator YP_005108840.1 842579 R 1112912 CDS YP_005108841.1 376278808 11685789 complement(843608..844555) 1 NC_016775.1 ribose ABC transporter, periplasmic D-ribose-binding protein 844555 rbsB-2 11685789 rbsB-2 Brucella suis VBI22 ribose ABC transporter, periplasmic D-ribose-binding protein YP_005108841.1 843608 R 1112912 CDS YP_005108842.1 376278809 11685790 complement(844722..845762) 1 NC_016775.1 similar to GP:15140211; identified by sequence similarity; putative; ribose ABC transporter, permease protein 845762 rbsC-3 11685790 rbsC-3 Brucella suis VBI22 ribose ABC transporter, permease protein YP_005108842.1 844722 R 1112912 CDS YP_005108843.1 376278810 11685791 complement(845786..847330) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00972; ribose ABC transporter, ATP-binding protein 847330 rbsA-3 11685791 rbsA-3 Brucella suis VBI22 ribose ABC transporter, ATP-binding protein YP_005108843.1 845786 R 1112912 CDS YP_005108844.1 376278811 11685792 complement(847327..847983) 1 NC_016775.1 similar to GP:15140209, and GP:15140209; identified by sequence similarity; putative; hypothetical protein 847983 11685792 BSVBI22_B0853 Brucella suis VBI22 hypothetical protein YP_005108844.1 847327 R 1112912 CDS YP_005108845.1 376278812 11685793 847963..848130 1 NC_016775.1 hypothetical protein 848130 11685793 BSVBI22_B0854 Brucella suis VBI22 hypothetical protein YP_005108845.1 847963 D 1112912 CDS YP_005108846.1 376278813 11685794 848582..848734 1 NC_016775.1 hypothetical protein 848734 11685794 BSVBI22_B0855 Brucella suis VBI22 hypothetical protein YP_005108846.1 848582 D 1112912 CDS YP_005108847.1 376278814 11685795 848727..850280 1 NC_016775.1 similar to GP:4204896, and GP:4204896; identified by sequence similarity; putative; erythritol kinase 850280 eryA 11685795 eryA Brucella suis VBI22 erythritol kinase YP_005108847.1 848727 D 1112912 CDS YP_005108848.1 376278815 11685796 850293..851801 1 NC_016775.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 851801 eryB 11685796 eryB Brucella suis VBI22 glycerol-3-phosphate dehydrogenase YP_005108848.1 850293 D 1112912 CDS YP_005108849.1 376278816 11685797 851809..852741 1 NC_016775.1 similar to GP:4204898, and GP:4204898; identified by sequence similarity; putative; D-erythrulose-1-phosphate dehydrogenase 852741 eryC 11685797 eryC Brucella suis VBI22 D-erythrulose-1-phosphate dehydrogenase YP_005108849.1 851809 D 1112912 CDS YP_005108850.1 376278817 11685798 852769..853719 1 NC_016775.1 similar to GP:4204899, and GP:4204899; identified by sequence similarity; putative; erythritol transcriptional regulator 853719 eryD 11685798 eryD Brucella suis VBI22 erythritol transcriptional regulator YP_005108850.1 852769 D 1112912 CDS YP_005108851.1 376278818 11685799 853807..854571 1 NC_016775.1 similar to GP:4204900; identified by sequence similarity; putative; DeoR family transcriptional regulator 854571 11685799 BSVBI22_B0860 Brucella suis VBI22 DeoR family transcriptional regulator YP_005108851.1 853807 D 1112912 CDS YP_005108852.1 376278819 11685800 854584..855354 1 NC_016775.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 855354 tpiA 11685800 tpiA Brucella suis VBI22 triosephosphate isomerase YP_005108852.1 854584 D 1112912 CDS YP_005108853.1 376278820 11685801 855366..855821 1 NC_016775.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 855821 11685801 BSVBI22_B0862 Brucella suis VBI22 ribose-5-phosphate isomerase B YP_005108853.1 855366 D 1112912 CDS YP_005108854.1 376278821 11685802 complement(855888..856952) 1 NC_016775.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 856952 fbaA 11685802 fbaA Brucella suis VBI22 fructose-1,6-bisphosphate aldolase YP_005108854.1 855888 R 1112912 CDS YP_005108855.1 376278822 11685803 complement(856983..858005) 1 NC_016775.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 858005 fbp 11685803 fbp Brucella suis VBI22 fructose-1,6-bisphosphatase YP_005108855.1 856983 R 1112912 CDS YP_005108856.1 376278823 11685804 complement(858002..858241) 1 NC_016775.1 hypothetical protein 858241 11685804 BSVBI22_B0865 Brucella suis VBI22 hypothetical protein YP_005108856.1 858002 R 1112912 CDS YP_005108857.1 376278824 11685805 complement(858439..859128) 1 NC_016775.1 similar to GP:15073394, and GP:15073394; identified by sequence similarity; putative; hypothetical protein 859128 11685805 BSVBI22_B0866 Brucella suis VBI22 hypothetical protein YP_005108857.1 858439 R 1112912 CDS YP_005108858.1 376278825 11685806 complement(859178..861004) 1 NC_016775.1 similar to GP:15076115; identified by sequence similarity; putative; GTP-binding protein TypA 861004 11685806 BSVBI22_B0867 Brucella suis VBI22 GTP-binding protein TypA YP_005108858.1 859178 R 1112912 CDS YP_005108859.1 376278826 11685807 complement(861247..862644) 1 NC_016775.1 similar to GP:17134323; identified by sequence similarity; putative; magnesium transporter 862644 mgtE 11685807 mgtE Brucella suis VBI22 magnesium transporter YP_005108859.1 861247 R 1112912 CDS YP_005108860.1 376278827 11685808 complement(862711..862875) 1 NC_016775.1 hypothetical protein 862875 11685808 BSVBI22_B0869 Brucella suis VBI22 hypothetical protein YP_005108860.1 862711 R 1112912 CDS YP_005108861.1 376278828 11685809 862970..865018 1 NC_016775.1 similar to SP:P24171; identified by sequence similarity; putative; peptidyl-dipeptidase Dcp 865018 dcp 11685809 dcp Brucella suis VBI22 peptidyl-dipeptidase Dcp YP_005108861.1 862970 D 1112912 CDS YP_005108862.1 376278829 11685810 complement(865047..865400) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00903; glyoxalase family protein 865400 11685810 BSVBI22_B0871 Brucella suis VBI22 glyoxalase family protein YP_005108862.1 865047 R 1112912 CDS YP_005108863.1 376278830 11685811 complement(865400..865606) 1 NC_016775.1 similar to GP:15076201, and GP:15076201; identified by sequence similarity; putative; hypothetical protein 865606 11685811 BSVBI22_B0872 Brucella suis VBI22 hypothetical protein YP_005108863.1 865400 R 1112912 CDS YP_005108864.1 376278831 11685813 866652..866858 1 NC_016775.1 hypothetical protein 866858 11685813 BSVBI22_B0874 Brucella suis VBI22 hypothetical protein YP_005108864.1 866652 D 1112912 CDS YP_005108865.1 376278832 11685814 866923..867528 1 NC_016775.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 867528 leuD 11685814 leuD Brucella suis VBI22 isopropylmalate isomerase small subunit YP_005108865.1 866923 D 1112912 CDS YP_005108866.1 376278833 11685815 867614..868036 1 NC_016775.1 similar to GP:15076200; identified by sequence similarity; putative; hypothetical protein 868036 11685815 BSVBI22_B0876 Brucella suis VBI22 hypothetical protein YP_005108866.1 867614 D 1112912 CDS YP_005108867.1 376278834 11685816 complement(868087..868509) 1 NC_016775.1 similar to GP:15073893, and SP:O68390; identified by sequence similarity; putative; organic hydroperoxide resistance protein 868509 ohr 11685816 ohr Brucella suis VBI22 organic hydroperoxide resistance protein YP_005108867.1 868087 R 1112912 CDS YP_005108868.1 376278835 11685817 868715..869170 1 NC_016775.1 similar to GP:14456720; identified by sequence similarity; putative; MarR family transcriptional regulator 869170 11685817 BSVBI22_B0878 Brucella suis VBI22 MarR family transcriptional regulator YP_005108868.1 868715 D 1112912 CDS YP_005108869.1 376278836 11685818 complement(869234..870268) 1 NC_016775.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 870268 asd 11685818 asd Brucella suis VBI22 aspartate-semialdehyde dehydrogenase YP_005108869.1 869234 R 1112912 CDS YP_005108870.1 376278837 11685819 870791..872689 1 NC_016775.1 similar to GP:15157678; identified by sequence similarity; putative; major facilitator family transporter 872689 11685819 BSVBI22_B0880 Brucella suis VBI22 major facilitator family transporter YP_005108870.1 870791 D 1112912 CDS YP_005108871.1 376278838 11685820 complement(872747..873799) 1 NC_016775.1 similar to GP:15073366; identified by sequence similarity; putative; ada regulatory protein, putative 873799 11685820 BSVBI22_B0881 Brucella suis VBI22 ada regulatory protein, putative YP_005108871.1 872747 R 1112912 CDS YP_005108872.1 376278839 11685821 complement(873940..875052) 1 NC_016775.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 875052 leuB 11685821 leuB Brucella suis VBI22 3-isopropylmalate dehydrogenase YP_005108872.1 873940 R 1112912 CDS YP_005108873.1 376278840 11685822 complement(875352..875546) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03966; hypothetical protein 875546 11685822 BSVBI22_B0883 Brucella suis VBI22 hypothetical protein YP_005108873.1 875352 R 1112912 CDS YP_005108874.1 376278841 11685823 complement(875723..876427) 1 NC_016775.1 similar to GP:14024485; identified by sequence similarity; putative; ATP-dependent protease La, putative 876427 11685823 BSVBI22_B0884 Brucella suis VBI22 ATP-dependent protease La, putative YP_005108874.1 875723 R 1112912 CDS YP_005108875.1 376278842 11685824 complement(876491..877465) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03745; thioredoxin 877465 trx-2 11685824 trx-2 Brucella suis VBI22 thioredoxin YP_005108875.1 876491 R 1112912 CDS YP_005108876.1 376278843 11685825 complement(877713..878255) 1 NC_016775.1 hypothetical protein 878255 11685825 BSVBI22_B0886 Brucella suis VBI22 hypothetical protein YP_005108876.1 877713 R 1112912 CDS YP_005108877.1 376278844 11685826 complement(878263..878454) 1 NC_016775.1 hypothetical protein 878454 11685826 BSVBI22_B0887 Brucella suis VBI22 hypothetical protein YP_005108877.1 878263 R 1112912 CDS YP_005108878.1 376278845 11685828 complement(878670..879236) 1 NC_016775.1 hypothetical protein 879236 11685828 BSVBI22_B0888 Brucella suis VBI22 hypothetical protein YP_005108878.1 878670 R 1112912 CDS YP_005108879.1 376278846 11685829 879251..879661 1 NC_016775.1 similar to GP:15155141; identified by sequence similarity; putative; hypothetical protein 879661 11685829 BSVBI22_B0889 Brucella suis VBI22 hypothetical protein YP_005108879.1 879251 D 1112912 CDS YP_005108880.1 376278847 11685830 complement(879674..880750) 1 NC_016775.1 catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase 880750 arcB 11685830 arcB Brucella suis VBI22 ornithine cyclodeaminase YP_005108880.1 879674 R 1112912 CDS YP_005108881.1 376278848 11685831 complement(880789..881709) 1 NC_016775.1 similar to SP:P10366, GB:U02070, GB:X63697, PID:41022, PID:41708, PID:509817, GB:U00096, PID:1736697, and PID:1788330; identified by sequence similarity; putative; arginase 881709 rocF 11685831 rocF Brucella suis VBI22 arginase YP_005108881.1 880789 R 1112912 CDS YP_005108882.1 376278849 11685832 881840..882277 1 NC_016775.1 identified by match to PFAM protein family HMM PF02954; AsnC family transcriptional regulator 882277 11685832 BSVBI22_B0892 Brucella suis VBI22 AsnC family transcriptional regulator YP_005108882.1 881840 D 1112912 CDS YP_005108883.1 376278850 11685833 complement(882315..883430) 1 NC_016775.1 similar to GP:15074497; identified by sequence similarity; putative; oxidoreductase, FMN-binding protein 883430 11685833 BSVBI22_B0893 Brucella suis VBI22 oxidoreductase, FMN-binding protein YP_005108883.1 882315 R 1112912 CDS YP_005108884.1 376278851 11685834 complement(883474..883782) 1 NC_016775.1 similar to GP:15074498; identified by sequence similarity; putative; ArsR family transcriptional regulator 883782 11685834 BSVBI22_B0894 Brucella suis VBI22 ArsR family transcriptional regulator YP_005108884.1 883474 R 1112912 CDS YP_005108885.1 376278852 11685835 884000..886303 1 NC_016775.1 similar to SP:P26606, GB:D11109, PID:216433, PID:466645, GB:U00096, and PID:1789924; identified by sequence similarity; putative; tex protein, putative 886303 11685835 BSVBI22_B0895 Brucella suis VBI22 tex protein, putative YP_005108885.1 884000 D 1112912 CDS YP_005108886.1 376278853 11685837 complement(886398..887681) 1 NC_016775.1 similar to GP:15157750; identified by sequence similarity; putative; oxidoreductase, putative 887681 11685837 BSVBI22_B0896 Brucella suis VBI22 oxidoreductase, putative YP_005108886.1 886398 R 1112912 CDS YP_005108887.1 376278854 11685838 complement(887781..888713) 1 NC_016775.1 similar to GP:15076313; identified by sequence similarity; putative; LysR family transcriptional regulator 888713 11685838 BSVBI22_B0897 Brucella suis VBI22 LysR family transcriptional regulator YP_005108887.1 887781 R 1112912 CDS YP_005108888.1 376278855 11685839 888861..890261 1 NC_016775.1 similar to GP:15076314, and GP:15076314; identified by sequence similarity; putative; hypothetical protein 890261 11685839 BSVBI22_B0898 Brucella suis VBI22 hypothetical protein YP_005108888.1 888861 D 1112912 CDS YP_005108889.1 376278856 11685840 890335..891867 1 NC_016775.1 similar to GP:15076316; identified by sequence similarity; putative; aldehyde dehydrogenase family protein 891867 11685840 BSVBI22_B0899 Brucella suis VBI22 aldehyde dehydrogenase family protein YP_005108889.1 890335 D 1112912 CDS YP_005108890.1 376278857 11685841 complement(892091..892975) 1 NC_016775.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 892975 purU 11685841 purU Brucella suis VBI22 formyltetrahydrofolate deformylase YP_005108890.1 892091 R 1112912 CDS YP_005108891.1 376278858 11685842 complement(893119..893847) 1 NC_016775.1 identified by match to PFAM protein family HMM PF01380; hypothetical protein 893847 11685842 BSVBI22_B0901 Brucella suis VBI22 hypothetical protein YP_005108891.1 893119 R 1112912 CDS YP_005108892.1 376278859 11685843 complement(893855..895021) 1 NC_016775.1 similar to GB:X56652, GB:L05921, GB:M10906, GB:M23698, GB:X51443, SP:P02735, PID:36308, PID:36317, PID:758679, PID:758681, PID:758683, PID:825714, PID:825715, PID:825716, PID:825717, and PID:939926; identified by sequence similarity; putative; N-acetylglucosamine-6-phosphate deacetylase 895021 nagA 11685843 nagA Brucella suis VBI22 N-acetylglucosamine-6-phosphate deacetylase YP_005108892.1 893855 R 1112912 CDS YP_005108893.1 376278860 11685844 complement(895018..896049) 1 NC_016775.1 similar to SP:Q9V249; identified by sequence similarity; putative; glucosamine-fructose-6-phosphate aminotransferase 896049 nagB 11685844 nagB Brucella suis VBI22 glucosamine-fructose-6-phosphate aminotransferase YP_005108893.1 895018 R 1112912 CDS YP_005108894.1 376278861 11685845 complement(896052..896777) 1 NC_016775.1 similar to GP:15073129; identified by sequence similarity; putative; GntR family transcriptional regulator 896777 11685845 BSVBI22_B0904 Brucella suis VBI22 GntR family transcriptional regulator YP_005108894.1 896052 R 1112912 CDS YP_005108895.1 376278862 11685846 complement(896922..899996) 1 NC_016775.1 similar to GP:17984539; identified by sequence similarity; putative; AcrB/AcrD/AcrF multidrug efflux protein 899996 11685846 BSVBI22_B0905 Brucella suis VBI22 AcrB/AcrD/AcrF multidrug efflux protein YP_005108895.1 896922 R 1112912 CDS YP_005108896.1 376278863 11685847 complement(899993..901099) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00998; secretion protein, putative 901099 11685847 BSVBI22_B0906 Brucella suis VBI22 secretion protein, putative YP_005108896.1 899993 R 1112912 CDS YP_005108897.1 376278864 11685848 complement(901096..902214) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00998; HlyD family secretion protein 902214 11685848 BSVBI22_B0907 Brucella suis VBI22 HlyD family secretion protein YP_005108897.1 901096 R 1112912 CDS YP_005108898.1 376278865 11685849 complement(902269..902484) 1 NC_016775.1 hypothetical protein 902484 11685849 BSVBI22_B0908 Brucella suis VBI22 hypothetical protein YP_005108898.1 902269 R 1112912 CDS YP_005108899.1 376278866 11685850 complement(902500..902799) 1 NC_016775.1 similar to GP:15156636, and GP:15156636; identified by sequence similarity; putative; hypothetical protein 902799 11685850 BSVBI22_B0909 Brucella suis VBI22 hypothetical protein YP_005108899.1 902500 R 1112912 CDS YP_005108900.1 376278867 11685851 complement(902796..905108) 1 NC_016775.1 similar to GP:15156635; identified by sequence similarity; putative; oxidoreductase, molybdopterin-binding, putative 905108 11685851 BSVBI22_B0910 Brucella suis VBI22 oxidoreductase, molybdopterin-binding, putative YP_005108900.1 902796 R 1112912 CDS YP_005108901.1 376278868 11685852 905313..906458 1 NC_016775.1 similar to GP:15141030; identified by sequence similarity; putative; L-lactate dehydrogenase 906458 lldD 11685852 lldD Brucella suis VBI22 L-lactate dehydrogenase YP_005108901.1 905313 D 1112912 CDS YP_005108902.1 376278869 11685853 906737..907591 1 NC_016775.1 similar to GP:15075757, and GP:17742129; identified by sequence similarity; putative; outer surface protein 907591 11685853 BSVBI22_B0912 Brucella suis VBI22 outer surface protein YP_005108902.1 906737 D 1112912 CDS YP_005108903.1 376278870 11685854 complement(907739..908206) 1 NC_016775.1 similar to GP:5805087, and GP:5805087; identified by sequence similarity; putative; alanine catabolic operon transcriptional regulator, putative 908206 11685854 BSVBI22_B0913 Brucella suis VBI22 alanine catabolic operon transcriptional regulator, putative YP_005108903.1 907739 R 1112912 CDS YP_005108904.1 376278871 11685855 908456..909646 1 NC_016775.1 identified by match to PFAM protein family HMM PF00842; alanine racemase 909646 alr 11685855 alr Brucella suis VBI22 alanine racemase YP_005108904.1 908456 D 1112912 CDS YP_005108905.1 376278872 11685856 909662..910912 1 NC_016775.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 910912 dadA 11685856 dadA Brucella suis VBI22 D-amino acid dehydrogenase small subunit YP_005108905.1 909662 D 1112912 CDS YP_005108906.1 376278873 11685857 complement(910955..911503) 1 NC_016775.1 similar to GP:15076318; identified by sequence similarity; putative; transcriptional regulator, putative 911503 11685857 BSVBI22_B0916 Brucella suis VBI22 transcriptional regulator, putative YP_005108906.1 910955 R 1112912 CDS YP_005108907.1 376278874 11685858 911649..912977 1 NC_016775.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; beta alanine--pyruvate transaminase 912977 11685858 BSVBI22_B0917 Brucella suis VBI22 beta alanine--pyruvate transaminase YP_005108907.1 911649 D 1112912 CDS YP_005108908.1 376278875 11685859 complement(913048..913791) 1 NC_016775.1 similar to SP:P22773; identified by sequence similarity; putative; histidine utilization repressor 913791 hutC 11685859 hutC Brucella suis VBI22 histidine utilization repressor YP_005108908.1 913048 R 1112912 CDS YP_005108909.1 376278876 11685860 complement(913803..915167) 1 NC_016775.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glu; N-formimino-L-glutamate deiminase 915167 11685860 BSVBI22_B0919 Brucella suis VBI22 N-formimino-L-glutamate deiminase YP_005108909.1 913803 R 1112912 CDS YP_005108910.1 376278877 11685861 915298..916515 1 NC_016775.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 916515 hutI 11685861 hutI Brucella suis VBI22 imidazolonepropionase YP_005108910.1 915298 D 1112912 CDS YP_005108911.1 376278878 11685862 916540..918075 1 NC_016775.1 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 918075 hutH 11685862 hutH Brucella suis VBI22 histidine ammonia-lyase YP_005108911.1 916540 D 1112912 CDS YP_005108912.1 376278879 11685863 918077..918877 1 NC_016775.1 similar to GP:15159359; identified by sequence similarity; putative; formiminoglutamase 918877 hutG 11685863 hutG Brucella suis VBI22 formiminoglutamase YP_005108912.1 918077 D 1112912 CDS YP_005108913.1 376278880 11685864 918888..920561 1 NC_016775.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 920561 hutU 11685864 hutU Brucella suis VBI22 urocanate hydratase YP_005108913.1 918888 D 1112912 CDS YP_005108914.1 376278881 11685865 920568..921191 1 NC_016775.1 similar to GP:15075729, and GP:15075729; identified by sequence similarity; putative; hypothetical protein 921191 11685865 BSVBI22_B0924 Brucella suis VBI22 hypothetical protein YP_005108914.1 920568 D 1112912 CDS YP_005108915.1 376278882 11685866 921279..922160 1 NC_016775.1 catalyzes the transamination of D-amino acids and their alpha-keto acids; D-amino acid aminotransferase 922160 11685866 BSVBI22_B0925 Brucella suis VBI22 D-amino acid aminotransferase YP_005108915.1 921279 D 1112912 CDS YP_005108916.1 376278883 11685867 complement(922311..923501) 1 NC_016775.1 similar to GB:M33819; identified by sequence similarity; putative; sugar ABC transporter, permease protein 923501 11685867 BSVBI22_B0926 Brucella suis VBI22 sugar ABC transporter, permease protein YP_005108916.1 922311 R 1112912 CDS YP_005108917.1 376278884 11685868 complement(923501..925090) 1 NC_016775.1 similar to GP:15485215; identified by sequence similarity; putative; sugar ABC transporter, ATP-binding protein 925090 11685868 BSVBI22_B0927 Brucella suis VBI22 sugar ABC transporter, ATP-binding protein YP_005108917.1 923501 R 1112912 CDS YP_005108918.1 376278885 11685869 complement(925236..926297) 1 NC_016775.1 similar to GB:D14697, GB:J05262, GB:M29863, SP:P14324, PID:182399, PID:182405, PID:285965, and PID:285965; identified by sequence similarity; putative; sugar ABC transporter, periplasmic sugar-binding protein 926297 11685869 BSVBI22_B0928 Brucella suis VBI22 sugar ABC transporter, periplasmic sugar-binding protein YP_005108918.1 925236 R 1112912 CDS YP_005108919.1 376278886 11685870 complement(926446..927078) 1 NC_016775.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 927078 11685870 BSVBI22_B0929 Brucella suis VBI22 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_005108919.1 926446 R 1112912 CDS YP_005108920.1 376278887 11685871 complement(927075..928004) 1 NC_016775.1 similar to GP:15155670, GB:M38180, GB:X55997, GB:M27137, SP:P14060, SP:P26439, PID:177191, PID:177196, PID:179468, PID:23862, PID:287844, and PID:306889; identified by sequence similarity; putative; 2-dehydro-3-deoxygalactonokinase 928004 dgoK 11685871 dgoK Brucella suis VBI22 2-dehydro-3-deoxygalactonokinase YP_005108920.1 927075 R 1112912 CDS YP_005108921.1 376278888 11685872 complement(928019..929824) 1 NC_016775.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; dihydroxy-acid dehydratase 929824 11685872 BSVBI22_B0931 Brucella suis VBI22 dihydroxy-acid dehydratase YP_005108921.1 928019 R 1112912 CDS YP_005108922.1 376278889 11685873 complement(929921..930856) 1 NC_016775.1 similar to GP:15156146, GB:L09118, GB:L23205, SP:Q05940, PID:1220370, PID:1770738, PID:292335, PID:296189, and PID:349712; identified by sequence similarity; putative; D-galactose 1-dehydrogenase, putative 930856 11685873 BSVBI22_B0932 Brucella suis VBI22 D-galactose 1-dehydrogenase, putative YP_005108922.1 929921 R 1112912 CDS YP_005108923.1 376278890 11685874 complement(930865..931857) 1 NC_016775.1 hypothetical protein 931857 11685874 BSVBI22_B0933 Brucella suis VBI22 hypothetical protein YP_005108923.1 930865 R 1112912 CDS YP_005108924.1 376278891 11685875 932127..932420 1 NC_016775.1 hypothetical protein 932420 11685875 BSVBI22_B0934 Brucella suis VBI22 hypothetical protein YP_005108924.1 932127 D 1112912 CDS YP_005108925.1 376278892 11685877 complement(933122..934807) 1 NC_016775.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; also known as acetolactate synthase large subunit; thiamine pyrophosphate protein 934807 11685877 BSVBI22_B0936 Brucella suis VBI22 thiamine pyrophosphate protein YP_005108925.1 933122 R 1112912 CDS YP_005108926.1 376278893 11685878 935031..935198 1 NC_016775.1 hypothetical protein 935198 11685878 BSVBI22_B0937 Brucella suis VBI22 hypothetical protein YP_005108926.1 935031 D 1112912 CDS YP_005108927.1 376278894 11685879 935223..936779 1 NC_016775.1 intracellular enzymes acting on low molecular weight D-amino acid amides, esters and oligopeptides containing D-amino acids; these proteases release the N-terminal D-amino acid from a peptide, and show higher affinity for D-Ala, D-Ser or D-Thr; no preference for the stereochemistry of the second amino acid; D-aminopeptidase 936779 11685879 BSVBI22_B0938 Brucella suis VBI22 D-aminopeptidase YP_005108927.1 935223 D 1112912 CDS YP_005108928.1 376278895 11685880 complement(936810..937829) 1 NC_016775.1 similar to GP:15075720, and SP:P45766; identified by sequence similarity; putative; amino acid ABC transporter, periplasmic amino acid-binding protein 937829 11685880 BSVBI22_B0939 Brucella suis VBI22 amino acid ABC transporter, periplasmic amino acid-binding protein YP_005108928.1 936810 R 1112912 CDS YP_005108929.1 376278896 11685881 complement(937933..940824) 1 NC_016775.1 annotated by RAST server; similar to GI:23464322; aminotransferase class-III 940824 11685881 BSVBI22_B0940 Brucella suis VBI22 aminotransferase class-III YP_005108929.1 937933 R 1112912 CDS YP_005108930.1 376278897 11685882 complement(941097..941240) 1 NC_016775.1 hypothetical protein 941240 11685882 BSVBI22_B0941 Brucella suis VBI22 hypothetical protein YP_005108930.1 941097 R 1112912 CDS YP_005108931.1 376278898 11685883 941254..941694 1 NC_016775.1 similar to GP:15075718; identified by sequence similarity; putative; AsnC family transcriptional regulator 941694 11685883 BSVBI22_B0942 Brucella suis VBI22 AsnC family transcriptional regulator YP_005108931.1 941254 D 1112912 CDS YP_005108932.1 376278899 11685884 complement(941910..942824) 1 NC_016775.1 similar to GP:15075996; identified by sequence similarity; putative; LysR family transcriptional regulator 942824 11685884 BSVBI22_B0943 Brucella suis VBI22 LysR family transcriptional regulator YP_005108932.1 941910 R 1112912 CDS YP_005108933.1 376278900 11685885 943089..944294 1 NC_016775.1 similar to GP:15159145, and GP:15075607; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative 944294 11685885 BSVBI22_B0944 Brucella suis VBI22 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative YP_005108933.1 943089 D 1112912 CDS YP_005108934.1 376278901 11685886 944307..945122 1 NC_016775.1 similar to GP:15159144; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, ATP-binding protein 945122 11685886 BSVBI22_B0945 Brucella suis VBI22 branched-chain amino acid ABC transporter, ATP-binding protein YP_005108934.1 944307 D 1112912 CDS YP_005108935.1 376278902 11685887 945115..945840 1 NC_016775.1 similar to GP:15075999, and SP:P22731; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, ATP-binding protein LivF, putative 945840 11685887 BSVBI22_B0946 Brucella suis VBI22 branched-chain amino acid ABC transporter, ATP-binding protein LivF, putative YP_005108935.1 945115 D 1112912 CDS YP_005108936.1 376278903 11685888 945845..946732 1 NC_016775.1 similar to GP:15076000; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, permease protein 946732 11685888 BSVBI22_B0947 Brucella suis VBI22 branched-chain amino acid ABC transporter, permease protein YP_005108936.1 945845 D 1112912 CDS YP_005108937.1 376278904 11685889 946734..947729 1 NC_016775.1 similar to GP:15159141; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, permease protein 947729 11685889 BSVBI22_B0948 Brucella suis VBI22 branched-chain amino acid ABC transporter, permease protein YP_005108937.1 946734 D 1112912 CDS YP_005108938.1 376278905 11685890 947793..949391 1 NC_016775.1 similar to GP:15076002; identified by sequence similarity; putative; GMC family oxidoreductase 949391 11685890 BSVBI22_B0949 Brucella suis VBI22 GMC family oxidoreductase YP_005108938.1 947793 D 1112912 CDS YP_005108939.1 376278906 11685891 949388..949531 1 NC_016775.1 hypothetical protein 949531 11685891 BSVBI22_B0950 Brucella suis VBI22 hypothetical protein YP_005108939.1 949388 D 1112912 CDS YP_005108940.1 376278907 11685892 949625..950461 1 NC_016775.1 identified by match to PFAM protein family HMM PF03734; YaeC family lipoprotein 950461 11685892 BSVBI22_B0951 Brucella suis VBI22 YaeC family lipoprotein YP_005108940.1 949625 D 1112912 CDS YP_005108941.1 376278908 11685893 950926..951984 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00972; ABC transporter, ATP-binding protein 951984 11685893 BSVBI22_B0952 Brucella suis VBI22 ABC transporter, ATP-binding protein YP_005108941.1 950926 D 1112912 CDS YP_005108942.1 376278909 11685894 951965..952630 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01594; ABC transporter, permease protein 952630 11685894 BSVBI22_B0953 Brucella suis VBI22 ABC transporter, permease protein YP_005108942.1 951965 D 1112912 CDS YP_005108943.1 376278910 11685895 complement(952643..953050) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00903; glyoxalase family protein 953050 11685895 BSVBI22_B0954 Brucella suis VBI22 glyoxalase family protein YP_005108943.1 952643 R 1112912 CDS YP_005108944.1 376278911 11685896 complement(953142..954029) 1 NC_016775.1 similar to GP:15075882; identified by sequence similarity; putative; TPR domain-containing protein 954029 11685896 BSVBI22_B0955 Brucella suis VBI22 TPR domain-containing protein YP_005108944.1 953142 R 1112912 CDS YP_005108945.1 376278912 11685897 954123..954284 1 NC_016775.1 hypothetical protein 954284 11685897 BSVBI22_B0956 Brucella suis VBI22 hypothetical protein YP_005108945.1 954123 D 1112912 CDS YP_005108946.1 376278913 11685898 complement(954568..954795) 1 NC_016775.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 954795 rpsU 11685898 rpsU Brucella suis VBI22 30S ribosomal protein S21 YP_005108946.1 954568 R 1112912 CDS YP_005108947.1 376278914 11685899 955148..956344 1 NC_016775.1 similar to GP:15156967, and GP:15156967; identified by sequence similarity; putative; hypothetical protein 956344 11685899 BSVBI22_B0958 Brucella suis VBI22 hypothetical protein YP_005108947.1 955148 D 1112912 CDS YP_005108948.1 376278915 11685900 complement(956419..956895) 1 NC_016775.1 similar to GB:X60708, GB:U13710, GB:U13711, GB:U13712, GB:U13713, GB:U13714, GB:U13715, GB:U13716, GB:U13717, GB:U13718, GB:U13719, GB:U13720, GB:U13721, GB:U13722, GB:U13723, GB:U13724, GB:U13725, GB:U13726, GB:U13727, GB:U13728, GB:U13729, GB:U13730, GB:U13731, GB:U13732, GB:U13733, GB:U13734, GB:U13735, GB:S79876, SP:P27487, PID:180083, PID:181570, PID:35336, and PID:535388; identified by sequence similarity; putative; nodulation protein N, putative 956895 11685900 BSVBI22_B0959 Brucella suis VBI22 nodulation protein N, putative YP_005108948.1 956419 R 1112912 CDS YP_005108949.1 376278916 11685901 complement(956970..957641) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01662; HAD superfamily hydrolase 957641 11685901 BSVBI22_B0960 Brucella suis VBI22 HAD superfamily hydrolase YP_005108949.1 956970 R 1112912 CDS YP_005108950.1 376278917 11685902 957837..959153 1 NC_016775.1 identified by match to PFAM protein family HMM PF03447; oxidoreductase, putative 959153 11685902 BSVBI22_B0961 Brucella suis VBI22 oxidoreductase, putative YP_005108950.1 957837 D 1112912 CDS YP_005108951.1 376278918 11685903 complement(959239..960639) 1 NC_016775.1 similar to GP:15075885, GB:M64979, GB:L14754, GB:L24544, SP:P38935, PID:401776, and PID:908917; identified by sequence similarity; putative; NAD(P) transhydrogenase, beta subunit 960639 pntB 11685903 pntB Brucella suis VBI22 NAD(P) transhydrogenase, beta subunit YP_005108951.1 959239 R 1112912 CDS YP_005108952.1 376278919 11685904 complement(960652..961071) 1 NC_016775.1 similar to GP:15075886, GB:V00497, GB:M25113, GB:U01317, GB:M36640, GB:M25660, GB:A01592, GB:A18171, GB:M11428, GB:M25079, GB:V00500, GB:L48213, GB:U20223, GB:V00499, GB:V00498, SP:P02023, SP:P02042, PID:1066755, PID:1066758, PID:1066761, PID:1066764, PID:1066767, PID:1066770, PID:1066773, PID:1066776, PID:1066779, and PID:455998; identified by sequence similarity; putative; NAD(P) transhydrogenase, alpha2 subunit 961071 pntAB 11685904 pntAB Brucella suis VBI22 NAD(P) transhydrogenase, alpha2 subunit YP_005108952.1 960652 R 1112912 CDS YP_005108953.1 376278920 11685905 complement(961071..962360) 1 NC_016775.1 similar to GB:X70218, SP:P33172, and PID:312814; identified by sequence similarity; putative; NAD(P) transhydrogenase, alpha subunit 962360 pntA 11685905 pntA Brucella suis VBI22 NAD(P) transhydrogenase, alpha subunit YP_005108953.1 961071 R 1112912 CDS YP_005108954.1 376278921 11685906 complement(962586..962810) 1 NC_016775.1 similar to GP:15075888, and GP:15075888; identified by sequence similarity; putative; hypothetical protein 962810 11685906 BSVBI22_B0965 Brucella suis VBI22 hypothetical protein YP_005108954.1 962586 R 1112912 CDS YP_005108955.1 376278922 11685907 962840..962974 1 NC_016775.1 hypothetical protein 962974 11685907 BSVBI22_B0966 Brucella suis VBI22 hypothetical protein YP_005108955.1 962840 D 1112912 CDS YP_005108956.1 376278923 11685908 complement(963014..963760) 1 NC_016775.1 hypothetical protein 963760 11685908 BSVBI22_B0967 Brucella suis VBI22 hypothetical protein YP_005108956.1 963014 R 1112912 CDS YP_005108957.1 376278924 11685909 complement(963868..963978) 1 NC_016775.1 hypothetical protein 963978 11685909 BSVBI22_B0968 Brucella suis VBI22 hypothetical protein YP_005108957.1 963868 R 1112912 CDS YP_005108958.1 376278925 11685911 complement(965501..967798) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00254; GGDEF domain-containing protein 967798 11685911 BSVBI22_B0970 Brucella suis VBI22 GGDEF domain-containing protein YP_005108958.1 965501 R 1112912 CDS YP_005108959.1 376278926 11685912 complement(968043..968183) 1 NC_016775.1 hypothetical protein 968183 11685912 BSVBI22_B0971 Brucella suis VBI22 hypothetical protein YP_005108959.1 968043 R 1112912 CDS YP_005108960.1 376278927 11685913 complement(968164..968913) 1 NC_016775.1 similar to GP:12698385, GB:M62800, GB:U01882, SP:P19474, PID:337485, PID:338490, PID:665918, and PID:747927; identified by sequence similarity; putative; 2-deoxy-d-gluconate 3-dehydrogenase, putative 968913 11685913 BSVBI22_B0972 Brucella suis VBI22 2-deoxy-d-gluconate 3-dehydrogenase, putative YP_005108960.1 968164 R 1112912 CDS YP_005108961.1 376278928 11685914 969148..969984 1 NC_016775.1 identified by match to PFAM protein family HMM PF00117; glutamine amidotransferase, class I 969984 11685914 BSVBI22_B0973 Brucella suis VBI22 glutamine amidotransferase, class I YP_005108961.1 969148 D 1112912 CDS YP_005108962.1 376278929 11685915 complement(970010..970984) 1 NC_016775.1 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase 970984 11685915 BSVBI22_B0974 Brucella suis VBI22 glycerate dehydrogenase YP_005108962.1 970010 R 1112912 CDS YP_005108963.1 376278930 11685916 complement(971070..972089) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01481; transcriptional regulator, putative 972089 11685916 BSVBI22_B0975 Brucella suis VBI22 transcriptional regulator, putative YP_005108963.1 971070 R 1112912 CDS YP_005108964.1 376278931 11685918 972906..973676 1 NC_016775.1 similar to GP:15075894, GB:X74863, SP:P52954, PID:1617116, and PID:510998; identified by sequence similarity; putative; creatinine amidohydrolase, putative 973676 11685918 BSVBI22_B0977 Brucella suis VBI22 creatinine amidohydrolase, putative YP_005108964.1 972906 D 1112912 CDS YP_005108965.1 376278932 11685919 973912..975036 1 NC_016775.1 similar to GP:15075895; identified by sequence similarity; putative; cobalamin synthesis protein/P47K family protein 975036 11685919 BSVBI22_B0978 Brucella suis VBI22 cobalamin synthesis protein/P47K family protein YP_005108965.1 973912 D 1112912 CDS YP_005108966.1 376278933 11685920 975155..976129 1 NC_016775.1 identified by match to PFAM protein family HMM PF00400; WD repeat-containing protein 976129 11685920 BSVBI22_B0979 Brucella suis VBI22 WD repeat-containing protein YP_005108966.1 975155 D 1112912 CDS YP_005108967.1 376278934 11685921 complement(976262..977128) 1 NC_016775.1 similar to GP:15075513, and GP:15075513; identified by sequence similarity; putative; hypothetical protein 977128 11685921 BSVBI22_B0980 Brucella suis VBI22 hypothetical protein YP_005108967.1 976262 R 1112912 CDS YP_005108968.1 376278935 11685922 977551..978510 1 NC_016775.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY 978510 11685922 BSVBI22_B0981 Brucella suis VBI22 putative sulfite oxidase subunit YedY YP_005108968.1 977551 D 1112912 CDS YP_005108969.1 376278936 11685923 978512..979174 1 NC_016775.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 979174 11685923 BSVBI22_B0982 Brucella suis VBI22 putative sulfite oxidase subunit YedZ YP_005108969.1 978512 D 1112912 CDS YP_005108970.1 376278937 11685924 complement(979382..979726) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00004; hypothetical protein 979726 11685924 BSVBI22_B0983 Brucella suis VBI22 hypothetical protein YP_005108970.1 979382 R 1112912 CDS YP_005108971.1 376278938 11685925 complement(979801..980754) 1 NC_016775.1 similar to GP:15139890; identified by sequence similarity; putative; ribose ABC transporter, permease protein 980754 rbsC-4 11685925 rbsC-4 Brucella suis VBI22 ribose ABC transporter, permease protein YP_005108971.1 979801 R 1112912 CDS YP_005108972.1 376278939 11685926 complement(980751..981710) 1 NC_016775.1 similar to SP:P04984; identified by sequence similarity; putative; ribose ABC transporter, permease protein 981710 rbsC-5 11685926 rbsC-5 Brucella suis VBI22 ribose ABC transporter, permease protein YP_005108972.1 980751 R 1112912 CDS YP_005108973.1 376278940 11685927 complement(981710..983218) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00955; ribose ABC transporter, ATP-binding protein 983218 rbsA-4 11685927 rbsA-4 Brucella suis VBI22 ribose ABC transporter, ATP-binding protein YP_005108973.1 981710 R 1112912 CDS YP_005108974.1 376278941 11685928 complement(983251..984318) 1 NC_016775.1 similar to GP:15139893; identified by sequence similarity; putative; ribose ABC transporter, periplasmic D-ribose-binding protein 984318 rbsB-3 11685928 rbsB-3 Brucella suis VBI22 ribose ABC transporter, periplasmic D-ribose-binding protein YP_005108974.1 983251 R 1112912 CDS YP_005108975.1 376278942 11685929 984620..985414 1 NC_016775.1 similar to GP:11275975; identified by sequence similarity; putative; IclR family transcriptional regulator 985414 11685929 BSVBI22_B0988 Brucella suis VBI22 IclR family transcriptional regulator YP_005108975.1 984620 D 1112912 CDS YP_005108976.1 376278943 11685930 complement(985508..986689) 1 NC_016775.1 similar to GP:5420003, and GP:5420003; identified by sequence similarity; putative; hypothetical protein 986689 11685930 BSVBI22_B0989 Brucella suis VBI22 hypothetical protein YP_005108976.1 985508 R 1112912 CDS YP_005108977.1 376278944 11685931 complement(986857..988887) 1 NC_016775.1 similar to GB:M90413, PID:153311, GB:Z22551, GB:D13629, GB:L25616, PID:285985, and PID:409466; identified by sequence similarity; putative; nosA protein, putative 988887 11685931 BSVBI22_B0990 Brucella suis VBI22 nosA protein, putative YP_005108977.1 986857 R 1112912 CDS YP_005108978.1 376278945 11685932 complement(988984..989391) 1 NC_016775.1 similar to GP:15156545, and GP:15156545; identified by sequence similarity; putative; hypothetical protein 989391 11685932 BSVBI22_B0991 Brucella suis VBI22 hypothetical protein YP_005108978.1 988984 R 1112912 CDS YP_005108979.1 376278946 11685933 complement(989544..989930) 1 NC_016775.1 similar to SP:P47233; identified by sequence similarity; putative; extradiol ring-cleaving dioxygenase, putative 989930 11685933 BSVBI22_B0992 Brucella suis VBI22 extradiol ring-cleaving dioxygenase, putative YP_005108979.1 989544 R 1112912 CDS YP_005108980.1 376278947 11685934 complement(990113..990718) 1 NC_016775.1 similar to SP:P81065, GB:J00117, GB:K03180, GB:K03187, GB:K03188, GB:K03189, GB:X00265, GB:X00266, GB:K03183, GB:K00092, GB:K03182, SP:P01229, SP:P01233, PID:1335012, PID:1335075, PID:180437, PID:180444, and PID:180453; identified by sequence similarity; putative; glutathione S-transferase, putative 990718 11685934 BSVBI22_B0993 Brucella suis VBI22 glutathione S-transferase, putative YP_005108980.1 990113 R 1112912 CDS YP_005108981.1 376278948 11685935 complement(990822..992123) 1 NC_016775.1 hypothetical protein 992123 11685935 BSVBI22_B0994 Brucella suis VBI22 hypothetical protein YP_005108981.1 990822 R 1112912 CDS YP_005108982.1 376278949 11685936 complement(992294..993403) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03772; GGDEF domain-containing protein 993403 11685936 BSVBI22_B0995 Brucella suis VBI22 GGDEF domain-containing protein YP_005108982.1 992294 R 1112912 CDS YP_005108983.1 376278950 11685937 complement(993638..994870) 1 NC_016775.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 994870 11685937 BSVBI22_B0996 Brucella suis VBI22 hydroxyglutarate oxidase YP_005108983.1 993638 R 1112912 CDS YP_005108984.1 376278951 11685938 995026..996024 1 NC_016775.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 996024 11685938 BSVBI22_B0997 Brucella suis VBI22 DNA polymerase III subunit epsilon YP_005108984.1 995026 D 1112912 CDS YP_005108985.1 376278952 11685939 complement(996100..996585) 1 NC_016775.1 putative amidase 996585 11685939 BSVBI22_B0998 Brucella suis VBI22 putative amidase YP_005108985.1 996100 R 1112912 CDS YP_005108986.1 376278953 11685940 complement(997504..998352) 1 NC_016775.1 similar to GP:15160122; identified by sequence similarity; putative; peptide ABC transporter, ATP-binding protein 998352 11685940 BSVBI22_B0999 Brucella suis VBI22 peptide ABC transporter, ATP-binding protein YP_005108986.1 997504 R 1112912 CDS YP_005108987.1 376278954 11685941 complement(998349..999374) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01188; peptide ABC transporter, ATP-binding protein 999374 11685941 BSVBI22_B1000 Brucella suis VBI22 peptide ABC transporter, ATP-binding protein YP_005108987.1 998349 R 1112912 CDS YP_005108988.1 376278955 11685942 complement(999371..1000231) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03772; peptide ABC transporter, permease protein 1000231 11685942 BSVBI22_B1001 Brucella suis VBI22 peptide ABC transporter, permease protein YP_005108988.1 999371 R 1112912 CDS YP_005108989.1 376278956 11685943 complement(1000228..1001181) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00528; peptide ABC transporter, permease protein 1001181 11685943 BSVBI22_B1002 Brucella suis VBI22 peptide ABC transporter, permease protein YP_005108989.1 1000228 R 1112912 CDS YP_005108990.1 376278957 11685944 complement(1001279..1002757) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01698; ABC transporter, periplasmic substrate-binding protein 1002757 11685944 BSVBI22_B1003 Brucella suis VBI22 ABC transporter, periplasmic substrate-binding protein YP_005108990.1 1001279 R 1112912 CDS YP_005108991.1 376278958 11685945 complement(1002780..1003538) 1 NC_016775.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 1003538 fabG 11685945 fabG Brucella suis VBI22 3-ketoacyl-(acyl-carrier-protein) reductase YP_005108991.1 1002780 R 1112912 CDS YP_005108992.1 376278959 11685946 complement(1003573..1005066) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01682; aldehyde dehydrogenase family protein 1005066 11685946 BSVBI22_B1005 Brucella suis VBI22 aldehyde dehydrogenase family protein YP_005108992.1 1003573 R 1112912 CDS YP_005108993.1 376278960 11685947 complement(1005050..1005736) 1 NC_016775.1 identified by match to PFAM protein family HMM PF01325; GntR family transcriptional regulator 1005736 11685947 BSVBI22_B1006 Brucella suis VBI22 GntR family transcriptional regulator YP_005108993.1 1005050 R 1112912 CDS YP_005108994.1 376278961 11685948 complement(1005836..1005982) 1 NC_016775.1 hypothetical protein 1005982 11685948 BSVBI22_B1007 Brucella suis VBI22 hypothetical protein YP_005108994.1 1005836 R 1112912 CDS YP_005108995.1 376278962 11685949 1006106..1007485 1 NC_016775.1 similar to SP:P76269; identified by sequence similarity; putative; transporter, putative 1007485 11685949 BSVBI22_B1008 Brucella suis VBI22 transporter, putative YP_005108995.1 1006106 D 1112912 CDS YP_005108996.1 376278963 11685951 1007879..1008946 1 NC_016775.1 hypothetical protein 1008946 11685951 BSVBI22_B1009 Brucella suis VBI22 hypothetical protein YP_005108996.1 1007879 D 1112912 CDS YP_005108997.1 376278964 11685952 complement(1009000..1009344) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00004; hypothetical protein 1009344 11685952 BSVBI22_B1010 Brucella suis VBI22 hypothetical protein YP_005108997.1 1009000 R 1112912 CDS YP_005108998.1 376278965 11685953 1009427..1009651 1 NC_016775.1 hypothetical protein 1009651 11685953 BSVBI22_B1011 Brucella suis VBI22 hypothetical protein YP_005108998.1 1009427 D 1112912 CDS YP_005108999.1 376278966 11685954 1009652..1009786 1 NC_016775.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1009786 rpmH 11685954 rpmH Brucella suis VBI22 50S ribosomal protein L34 YP_005108999.1 1009652 D 1112912 CDS YP_005109000.1 376278967 11685955 1009824..1010261 1 NC_016775.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1010261 rnpA 11685955 rnpA Brucella suis VBI22 ribonuclease P YP_005109000.1 1009824 D 1112912 CDS YP_005109001.1 376278968 11685956 1010251..1012083 1 NC_016775.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 1012083 11685956 BSVBI22_B1014 Brucella suis VBI22 putative inner membrane protein translocase component YidC YP_005109001.1 1010251 D 1112912 CDS YP_005109002.1 376278969 11685957 1012125..1012928 1 NC_016775.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1012928 engB 11685957 engB Brucella suis VBI22 ribosome biogenesis GTP-binding protein YsxC YP_005109002.1 1012125 D 1112912 CDS YP_005109003.1 376278970 11685958 1013099..1013989 1 NC_016775.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 1013989 argB 11685958 argB Brucella suis VBI22 acetylglutamate kinase YP_005109003.1 1013099 D 1112912 CDS YP_005109004.1 376278971 11685960 1014063..1014767 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01668; HAD superfamily hydrolase 1014767 11685960 BSVBI22_B1017 Brucella suis VBI22 HAD superfamily hydrolase YP_005109004.1 1014063 D 1112912 CDS YP_005109005.1 376278972 11685961 complement(1014829..1015659) 1 NC_016775.1 similar to GP:15073363, and GP:15073363; identified by sequence similarity; putative; hypothetical protein 1015659 11685961 BSVBI22_B1018 Brucella suis VBI22 hypothetical protein YP_005109005.1 1014829 R 1112912 CDS YP_005109006.1 376278973 11685962 1015878..1016732 1 NC_016775.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1016732 dapD 11685962 dapD Brucella suis VBI22 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_005109006.1 1015878 D 1112912 CDS YP_005109007.1 376278974 11685963 complement(1016876..1017430) 1 NC_016775.1 hypothetical protein 1017430 11685963 BSVBI22_B1020 Brucella suis VBI22 hypothetical protein YP_005109007.1 1016876 R 1112912 CDS YP_005109008.1 376278975 11685964 1017583..1017675 1 NC_016775.1 hypothetical protein 1017675 11685964 BSVBI22_B1021 Brucella suis VBI22 hypothetical protein YP_005109008.1 1017583 D 1112912 CDS YP_005109009.1 376278976 11685965 1017715..1018902 1 NC_016775.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1018902 dapE 11685965 dapE Brucella suis VBI22 succinyl-diaminopimelate desuccinylase YP_005109009.1 1017715 D 1112912 CDS YP_005109010.1 376278977 11685966 1018965..1019570 1 NC_016775.1 similar to GP:15073353; identified by sequence similarity; putative; hypothetical protein 1019570 11685966 BSVBI22_B1023 Brucella suis VBI22 hypothetical protein YP_005109010.1 1018965 D 1112912 CDS YP_005109011.1 376278978 11685967 complement(1019745..1020500) 1 NC_016775.1 tRNA pseudouridine synthase A 1020500 truA 11685967 truA Brucella suis VBI22 tRNA pseudouridine synthase A YP_005109011.1 1019745 R 1112912 CDS YP_005109012.1 376278979 11685968 complement(1020504..1021424) 1 NC_016775.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1021424 fmt 11685968 fmt Brucella suis VBI22 methionyl-tRNA formyltransferase YP_005109012.1 1020504 R 1112912 CDS YP_005109013.1 376278980 11685969 complement(1021424..1021987) 1 NC_016775.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1021987 def 11685969 def Brucella suis VBI22 peptide deformylase YP_005109013.1 1021424 R 1112912 CDS YP_005109014.1 376278981 11685970 1022054..1023277 1 NC_016775.1 similar to GP:14024818; identified by sequence similarity; putative; hypothetical protein 1023277 11685970 BSVBI22_B1027 Brucella suis VBI22 hypothetical protein YP_005109014.1 1022054 D 1112912 CDS YP_005109015.1 376278982 11685971 complement(1023506..1023811) 1 NC_016775.1 similar to GP:15073194, and GP:15073194; identified by sequence similarity; putative; hypothetical protein 1023811 11685971 BSVBI22_B1028 Brucella suis VBI22 hypothetical protein YP_005109015.1 1023506 R 1112912 CDS YP_005109016.1 376278983 11685972 1023920..1024201 1 NC_016775.1 hypothetical protein 1024201 11685972 BSVBI22_B1029 Brucella suis VBI22 hypothetical protein YP_005109016.1 1023920 D 1112912 CDS YP_005109017.1 376278984 11685973 complement(1024447..1026255) 1 NC_016775.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1026255 lepA 11685973 lepA Brucella suis VBI22 GTP-binding protein LepA YP_005109017.1 1024447 R 1112912 CDS YP_005109018.1 376278985 11685974 complement(1026252..1026383) 1 NC_016775.1 hypothetical protein 1026383 11685974 BSVBI22_B1031 Brucella suis VBI22 hypothetical protein YP_005109018.1 1026252 R 1112912 CDS YP_005109019.1 376278986 11685975 1026419..1027405 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01181; NADH-ubiquinone oxidoreductase, putative 1027405 11685975 BSVBI22_B1032 Brucella suis VBI22 NADH-ubiquinone oxidoreductase, putative YP_005109019.1 1026419 D 1112912 CDS YP_005109020.1 376278987 11685976 complement(1027506..1028312) 1 NC_016775.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 1028312 uppP 11685976 uppP Brucella suis VBI22 undecaprenyl pyrophosphate phosphatase YP_005109020.1 1027506 R 1112912 CDS YP_005109021.1 376278988 11685977 complement(1028317..1028520) 1 NC_016775.1 hypothetical protein 1028520 11685977 BSVBI22_B1034 Brucella suis VBI22 hypothetical protein YP_005109021.1 1028317 R 1112912 CDS YP_005109022.1 376278989 11685978 1028568..1029260 1 NC_016775.1 identified by match to PFAM protein family HMM PF03578; glutathione S-transferase family protein 1029260 11685978 BSVBI22_B1035 Brucella suis VBI22 glutathione S-transferase family protein YP_005109022.1 1028568 D 1112912 CDS YP_005109023.1 376278990 11685979 1029241..1030437 1 NC_016775.1 identified by match to PFAM protein family HMM PF00037; iron-sulfur cluster-binding protein, putative 1030437 11685979 BSVBI22_B1036 Brucella suis VBI22 iron-sulfur cluster-binding protein, putative YP_005109023.1 1029241 D 1112912 CDS YP_005109024.1 376278991 11685980 1030439..1031308 1 NC_016775.1 similar to GP:15073254; identified by sequence similarity; putative; hypothetical protein 1031308 11685980 BSVBI22_B1037 Brucella suis VBI22 hypothetical protein YP_005109024.1 1030439 D 1112912 CDS YP_005109025.1 376278992 11685981 1031309..1032331 1 NC_016775.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 1032331 mepA 11685981 mepA Brucella suis VBI22 penicillin-insensitive murein endopeptidase YP_005109025.1 1031309 D 1112912 CDS YP_005109026.1 376278993 11685982 1032484..1032861 1 NC_016775.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1032861 mgsA 11685982 mgsA Brucella suis VBI22 methylglyoxal synthase YP_005109026.1 1032484 D 1112912 CDS YP_005109027.1 376278994 11685983 1032942..1033973 1 NC_016775.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1033973 glk 11685983 glk Brucella suis VBI22 glucokinase YP_005109027.1 1032942 D 1112912 CDS YP_005109028.1 376278995 11685984 1034200..1036029 1 NC_016775.1 similar to GB:U09086, GB:U09087, GB:U09088, GB:S76736, SP:P42166, SP:P42167, PID:508725, PID:508727, PID:508729, PID:885683, and PID:885684; identified by sequence similarity; putative; ABC transporter, ATP-binding/permease protein 1036029 11685984 BSVBI22_B1041 Brucella suis VBI22 ABC transporter, ATP-binding/permease protein YP_005109028.1 1034200 D 1112912 CDS YP_005109029.1 376278996 11685985 1036059..1036865 1 NC_016775.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1036865 dapB 11685985 dapB Brucella suis VBI22 dihydrodipicolinate reductase YP_005109029.1 1036059 D 1112912 CDS YP_005109030.1 376278997 11685986 1036902..1037522 1 NC_016775.1 catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1037522 gpm 11685986 gpm Brucella suis VBI22 phosphoglyceromutase YP_005109030.1 1036902 D 1112912 CDS YP_005109031.1 376278998 11685988 1037943..1039694 1 NC_016775.1 identified by match to PFAM protein family HMM PF03663; hypothetical protein 1039694 11685988 BSVBI22_B1044 Brucella suis VBI22 hypothetical protein YP_005109031.1 1037943 D 1112912 CDS YP_005109032.1 376278999 11685989 1040205..1040828 1 NC_016775.1 similar to GP:3128327, GB:U05040, and PID:460152; identified by sequence similarity; putative; nitroreductase family protein 1040828 11685989 BSVBI22_B1045 Brucella suis VBI22 nitroreductase family protein YP_005109032.1 1040205 D 1112912 CDS YP_005109033.1 376279000 11685990 1041026..1041472 1 NC_016775.1 similar to GP:15155425; identified by sequence similarity; putative; universal stress protein 1041472 11685990 BSVBI22_B1046 Brucella suis VBI22 universal stress protein YP_005109033.1 1041026 D 1112912 CDS YP_005109034.1 376279001 11685991 complement(1041589..1041807) 1 NC_016775.1 hypothetical protein 1041807 11685991 BSVBI22_B1047 Brucella suis VBI22 hypothetical protein YP_005109034.1 1041589 R 1112912 CDS YP_005109035.1 376279002 11685992 1041961..1042392 1 NC_016775.1 hypothetical protein 1042392 11685992 BSVBI22_B1048 Brucella suis VBI22 hypothetical protein YP_005109035.1 1041961 D 1112912 CDS YP_005109036.1 376279003 11685993 1042394..1043794 1 NC_016775.1 similar to GP:3336914; identified by sequence similarity; putative; aldehyde dehydrogenase family protein 1043794 11685993 BSVBI22_B1049 Brucella suis VBI22 aldehyde dehydrogenase family protein YP_005109036.1 1042394 D 1112912 CDS YP_005109037.1 376279004 11685994 1043949..1044806 1 NC_016775.1 similar to GP:15074185, and GP:15074185; identified by sequence similarity; putative; endonuclease/exonuclease/phosphatase family protein 1044806 11685994 BSVBI22_B1050 Brucella suis VBI22 endonuclease/exonuclease/phosphatase family protein YP_005109037.1 1043949 D 1112912 CDS YP_005109038.1 376279005 11685995 complement(1044816..1046276) 1 NC_016775.1 similar to GP:15157671, and SP:O66043; identified by sequence similarity; putative; cardiolipin synthase 1046276 cls 11685995 cls Brucella suis VBI22 cardiolipin synthase YP_005109038.1 1044816 R 1112912 CDS YP_005109039.1 376279006 11685997 1046448..1047011 1 NC_016775.1 hypothetical protein 1047011 11685997 BSVBI22_B1052 Brucella suis VBI22 hypothetical protein YP_005109039.1 1046448 D 1112912 CDS YP_005109040.1 376279007 11685998 complement(1047023..1047136) 1 NC_016775.1 hypothetical protein 1047136 11685998 BSVBI22_B1053 Brucella suis VBI22 hypothetical protein YP_005109040.1 1047023 R 1112912 CDS YP_005109041.1 376279008 11685999 1047172..1048749 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01393; peptide chain release factor 3 1048749 prfC 11685999 prfC Brucella suis VBI22 peptide chain release factor 3 YP_005109041.1 1047172 D 1112912 CDS YP_005109042.1 376279009 11686000 complement(1048746..1049966) 1 NC_016775.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 1049966 coaBC 11686000 coaBC Brucella suis VBI22 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_005109042.1 1048746 R 1112912 CDS YP_005109043.1 376279010 11686001 complement(1049997..1051580) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00069; ubiquinone biosynthesis protein UbiB 1051580 ubiB 11686001 ubiB Brucella suis VBI22 ubiquinone biosynthesis protein UbiB YP_005109043.1 1049997 R 1112912 CDS YP_005109044.1 376279011 11686002 complement(1051629..1052438) 1 NC_016775.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 1052438 ubiE 11686002 ubiE Brucella suis VBI22 ubiquinone/menaquinone biosynthesis methyltransferase YP_005109044.1 1051629 R 1112912 CDS YP_005109045.1 376279012 11686003 1052749..1053375 1 NC_016775.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1053375 upp 11686003 upp Brucella suis VBI22 uracil phosphoribosyltransferase YP_005109045.1 1052749 D 1112912 CDS YP_005109046.1 376279013 11686004 1053486..1053692 1 NC_016775.1 identified by match to PFAM protein family HMM PF03670; hypothetical protein 1053692 11686004 BSVBI22_B1059 Brucella suis VBI22 hypothetical protein YP_005109046.1 1053486 D 1112912 CDS YP_005109047.1 376279014 11686005 complement(1053705..1054361) 1 NC_016775.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 1054361 msrA 11686005 msrA Brucella suis VBI22 methionine sulfoxide reductase A YP_005109047.1 1053705 R 1112912 CDS YP_005109048.1 376279015 11686006 complement(1054384..1054707) 1 NC_016775.1 hypothetical protein 1054707 11686006 BSVBI22_B1061 Brucella suis VBI22 hypothetical protein YP_005109048.1 1054384 R 1112912 CDS YP_005109049.1 376279016 11686007 complement(1054685..1054837) 1 NC_016775.1 hypothetical protein 1054837 11686007 BSVBI22_B1062 Brucella suis VBI22 hypothetical protein YP_005109049.1 1054685 R 1112912 CDS YP_005109050.1 376279017 11686009 complement(1055379..1056287) 1 NC_016775.1 similar to GP:581026, GB:U12707, GB:U19927, GB:U18935, and PID:622987; identified by sequence similarity; putative; IS3 family transposase orfB 1056287 11686009 BSVBI22_B1063 Brucella suis VBI22 IS3 family transposase orfB YP_005109050.1 1055379 R 1112912 CDS YP_005109051.1 376279018 11686010 complement(1056284..1056565) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01199; IS3 family transposase orfA 1056565 11686010 BSVBI22_B1064 Brucella suis VBI22 IS3 family transposase orfA YP_005109051.1 1056284 R 1112912 CDS YP_005109052.1 376279019 11686011 1056807..1057538 1 NC_016775.1 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 1057538 11686011 BSVBI22_B1065 Brucella suis VBI22 GntR family transcriptional regulator YP_005109052.1 1056807 D 1112912 CDS YP_005109053.1 376279020 11686012 1057535..1057663 1 NC_016775.1 hypothetical protein 1057663 11686012 BSVBI22_B1066 Brucella suis VBI22 hypothetical protein YP_005109053.1 1057535 D 1112912 CDS YP_005109054.1 376279021 11686013 complement(1057734..1059176) 1 NC_016775.1 similar to GP:15159844; identified by sequence similarity; putative; aldehyde dehydrogenase family protein 1059176 11686013 BSVBI22_B1067 Brucella suis VBI22 aldehyde dehydrogenase family protein YP_005109054.1 1057734 R 1112912 CDS YP_005109055.1 376279022 11686014 complement(1059188..1060450) 1 NC_016775.1 similar to GP:14587414; identified by sequence similarity; putative; CAIB/BAIF family protein 1060450 11686014 BSVBI22_B1068 Brucella suis VBI22 CAIB/BAIF family protein YP_005109055.1 1059188 R 1112912 CDS YP_005109056.1 376279023 11686015 complement(1060506..1061510) 1 NC_016775.1 similar to GP:3402247; identified by sequence similarity; putative; peptide ABC transporter, ATP-binding protein 1061510 11686015 BSVBI22_B1069 Brucella suis VBI22 peptide ABC transporter, ATP-binding protein YP_005109056.1 1060506 R 1112912 CDS YP_005109057.1 376279024 11686016 complement(1061503..1062540) 1 NC_016775.1 similar to GB:M23592, GB:M23593, GB:M23594, GB:M23595, GB:M20841, GB:M74587, GB:M59316, GB:M31145, GB:X12385, GB:X15002, GB:X13405, GB:Y00856, SP:P08833, PID:183118, PID:184810, PID:184812, PID:184826, PID:32609, PID:33014, PID:35572, and PID:35575; identified by sequence similarity; putative; peptide ABC transporter, ATP-binding protein 1062540 11686016 BSVBI22_B1070 Brucella suis VBI22 peptide ABC transporter, ATP-binding protein YP_005109057.1 1061503 R 1112912 CDS YP_005109058.1 376279025 11686018 complement(1062553..1063398) 1 NC_016775.1 similar to SP:P94312; identified by sequence similarity; putative; peptide ABC transporter, permease protein 1063398 11686018 BSVBI22_B1071 Brucella suis VBI22 peptide ABC transporter, permease protein YP_005109058.1 1062553 R 1112912 CDS YP_005109059.1 376279026 11686019 complement(1063410..1064423) 1 NC_016775.1 similar to SP:P94311; identified by sequence similarity; putative; peptide ABC transporter, permease protein 1064423 11686019 BSVBI22_B1072 Brucella suis VBI22 peptide ABC transporter, permease protein YP_005109059.1 1063410 R 1112912 CDS YP_005109060.1 376279027 11686020 1064599..1065405 1 NC_016775.1 identified by match to PFAM protein family HMM PF01614; IclR family transcriptional regulator 1065405 11686020 BSVBI22_B1073 Brucella suis VBI22 IclR family transcriptional regulator YP_005109060.1 1064599 D 1112912 CDS YP_005109061.1 376279028 11686022 complement(1066835..1068454) 1 NC_016775.1 similar to GB:L17071, SP:Q07608, GB:U23753, PID:310304, and PID:763542; identified by sequence similarity; putative; ABC transporter, periplasmic substrate-binding protein, putative 1068454 11686022 BSVBI22_B1075 Brucella suis VBI22 ABC transporter, periplasmic substrate-binding protein, putative YP_005109061.1 1066835 R 1112912 CDS YP_005109062.1 376279029 11686024 complement(1070671..1072176) 1 NC_016775.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxy-acyl-CoA dehydrogenase 1072176 11686024 BSVBI22_B1077 Brucella suis VBI22 3-hydroxy-acyl-CoA dehydrogenase YP_005109062.1 1070671 R 1112912 CDS YP_005109063.1 376279030 11686025 complement(1072193..1072975) 1 NC_016775.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1072975 11686025 BSVBI22_B1078 Brucella suis VBI22 enoyl-CoA hydratase YP_005109063.1 1072193 R 1112912 CDS YP_005109064.1 376279031 11686026 1073158..1074300 1 NC_016775.1 similar to SP:P45857; identified by sequence similarity; putative; acyl-CoA dehydrogenase 1074300 11686026 BSVBI22_B1079 Brucella suis VBI22 acyl-CoA dehydrogenase YP_005109064.1 1073158 D 1112912 CDS YP_005109065.1 376279032 11686027 1074626..1076911 1 NC_016775.1 similar to SP:P15558; identified by sequence similarity; putative; penicillin amidase family protein 1076911 11686027 BSVBI22_B1080 Brucella suis VBI22 penicillin amidase family protein YP_005109065.1 1074626 D 1112912 CDS YP_005109066.1 376279033 11686028 1076934..1078478 1 NC_016775.1 similar to GP:15160115, and SP:P55669; identified by sequence similarity; putative; peptide ABC transporter, periplasmic peptide-binding protein 1078478 11686028 BSVBI22_B1081 Brucella suis VBI22 peptide ABC transporter, periplasmic peptide-binding protein YP_005109066.1 1076934 D 1112912 CDS YP_005109067.1 376279034 11686029 complement(1078528..1078623) 1 NC_016775.1 hypothetical protein 1078623 11686029 BSVBI22_B1082 Brucella suis VBI22 hypothetical protein YP_005109067.1 1078528 R 1112912 CDS YP_005109068.1 376279035 11686030 1078635..1079579 1 NC_016775.1 similar to GP:10172641, and GP:18092570; identified by sequence similarity; putative; peptide ABC transporter, permease protein, putative 1079579 11686030 BSVBI22_B1083 Brucella suis VBI22 peptide ABC transporter, permease protein, putative YP_005109068.1 1078635 D 1112912 CDS YP_005109069.1 376279036 11686031 1079572..1080462 1 NC_016775.1 similar to GP:15160117, and SP:P94312; identified by sequence similarity; putative; peptide ABC transporter, permease protein, putative 1080462 11686031 BSVBI22_B1084 Brucella suis VBI22 peptide ABC transporter, permease protein, putative YP_005109069.1 1079572 D 1112912 CDS YP_005109070.1 376279037 11686032 1080465..1081463 1 NC_016775.1 similar to GP:15158781; identified by sequence similarity; putative; peptide ABC transporter, ATP-binding protein, putative 1081463 11686032 BSVBI22_B1085 Brucella suis VBI22 peptide ABC transporter, ATP-binding protein, putative YP_005109070.1 1080465 D 1112912 CDS YP_005109071.1 376279038 11686034 1082687..1083400 1 NC_016775.1 similar to GP:14523620; identified by sequence similarity; putative; transcriptional regulator, putative 1083400 11686034 BSVBI22_B1087 Brucella suis VBI22 transcriptional regulator, putative YP_005109071.1 1082687 D 1112912 CDS YP_005109072.1 376279039 11686035 1083466..1085022 1 NC_016775.1 similar to GP:18092565; identified by sequence similarity; putative; oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, putative 1085022 11686035 BSVBI22_B1088 Brucella suis VBI22 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, putative YP_005109072.1 1083466 D 1112912 CDS YP_005109073.1 376279040 11686036 1085058..1086068 1 NC_016775.1 similar to SP:P94311; identified by sequence similarity; putative; peptide ABC transporter, permease protein 1086068 11686036 BSVBI22_B1089 Brucella suis VBI22 peptide ABC transporter, permease protein YP_005109073.1 1085058 D 1112912 CDS YP_005109074.1 376279041 11686037 1086065..1086898 1 NC_016775.1 similar to SP:P94312; identified by sequence similarity; putative; peptide ABC transporter, permease protein, putative 1086898 11686037 BSVBI22_B1090 Brucella suis VBI22 peptide ABC transporter, permease protein, putative YP_005109074.1 1086065 D 1112912 CDS YP_005109075.1 376279042 11686039 1087886..1088863 1 NC_016775.1 similar to SP:Q53194, GB:M62834, SP:P24093, GB:X69102, PID:145801, PID:433881, PID:639970, and SP:Q57254; identified by sequence similarity; putative; oligopeptide ABC transporter, ATP-binding protein, putative 1088863 11686039 BSVBI22_B1092 Brucella suis VBI22 oligopeptide ABC transporter, ATP-binding protein, putative YP_005109075.1 1087886 D 1112912 CDS YP_005109076.1 376279043 11686040 1088863..1089735 1 NC_016775.1 similar to GB:M20867, GB:M18377, GB:J03248, GB:M17697, GB:M37154, GB:X07769, GB:X53146, GB:X66300, SP:P00367, SP:P49448, PID:1335082, PID:183054, PID:183056, PID:183058, PID:183060, PID:183062, PID:31707, PID:31799, PID:478988, and PID:579924; identified by sequence similarity; putative; gluconolactonase, putative 1089735 11686040 BSVBI22_B1093 Brucella suis VBI22 gluconolactonase, putative YP_005109076.1 1088863 D 1112912 CDS YP_005109077.1 376279044 11686041 1089750..1091168 1 NC_016775.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1091168 11686041 BSVBI22_B1094 Brucella suis VBI22 amidase YP_005109077.1 1089750 D 1112912 CDS YP_005109078.1 376279045 11686043 complement(1092288..1093091) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00969; polyamine ABC transporter, permease protein 1093091 11686043 BSVBI22_B1096 Brucella suis VBI22 polyamine ABC transporter, permease protein YP_005109078.1 1092288 R 1112912 CDS YP_005109079.1 376279046 11686044 complement(1093088..1093903) 1 NC_016775.1 similar to SP:P23860, GB:L26967, SP:P12780, PID:152249, and PID:435107; identified by sequence similarity; putative; polyamine ABC transporter, permease protein, putative 1093903 11686044 BSVBI22_B1097 Brucella suis VBI22 polyamine ABC transporter, permease protein, putative YP_005109079.1 1093088 R 1112912 CDS YP_005109080.1 376279047 11686046 1095364..1096569 1 NC_016775.1 identified by match to PFAM protein family HMM PF03781; glutamate-1-semialdehyde 2,1-aminomutase, putative 1096569 11686046 BSVBI22_B1099 Brucella suis VBI22 glutamate-1-semialdehyde 2,1-aminomutase, putative YP_005109080.1 1095364 D 1112912 CDS YP_005109081.1 376279048 11686047 1096719..1098398 1 NC_016775.1 hypothetical protein 1098398 11686047 BSVBI22_B1100 Brucella suis VBI22 hypothetical protein YP_005109081.1 1096719 D 1112912 CDS YP_005109082.1 376279049 11686048 1098594..1099253 1 NC_016775.1 similar to GP:15075256, GB:X12466, GB:M37716, GB:M15919, SP:P08578, PID:338267, PID:338269, and PID:35105; identified by sequence similarity; putative; L-fuculose phosphate aldolase, putative 1099253 11686048 BSVBI22_B1101 Brucella suis VBI22 L-fuculose phosphate aldolase, putative YP_005109082.1 1098594 D 1112912 CDS YP_005109083.1 376279050 11686049 1099348..1100607 1 NC_016775.1 similar to GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, PID:386807, GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, and PID:386807; identified by sequence similarity; putative; hypothetical protein 1100607 11686049 BSVBI22_B1102 Brucella suis VBI22 hypothetical protein YP_005109083.1 1099348 D 1112912 CDS YP_005109084.1 376279051 11686050 1100585..1101097 1 NC_016775.1 hypothetical protein 1101097 11686050 BSVBI22_B1103 Brucella suis VBI22 hypothetical protein YP_005109084.1 1100585 D 1112912 CDS YP_005109085.1 376279052 11686051 complement(1101106..1101390) 1 NC_016775.1 identified by match to PFAM protein family HMM PF02452; pemK family protein 1101390 11686051 BSVBI22_B1104 Brucella suis VBI22 pemK family protein YP_005109085.1 1101106 R 1112912 CDS YP_005109086.1 376279053 11686053 1102757..1103038 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01199; IS3 family transposase orfA 1103038 11686053 BSVBI22_B1106 Brucella suis VBI22 IS3 family transposase orfA YP_005109086.1 1102757 D 1112912 CDS YP_005109087.1 376279054 11686054 1103035..1103916 1 NC_016775.1 similar to GP:581026, GB:U12707, GB:U19927, GB:U18935, and PID:622987; identified by sequence similarity; putative; IS3 family transposase orfB 1103916 11686054 BSVBI22_B1107 Brucella suis VBI22 IS3 family transposase orfB YP_005109087.1 1103035 D 1112912 CDS YP_005109088.1 376279055 11686061 1110409..1111275 1 NC_016775.1 similar to GP:14024748, and GP:14024748; identified by sequence similarity; putative; hypothetical protein 1111275 11686061 BSVBI22_B1108 Brucella suis VBI22 hypothetical protein YP_005109088.1 1110409 D 1112912 CDS YP_005109089.1 376279056 11686062 1111591..1111986 1 NC_016775.1 identified by match to PFAM protein family HMM PF02082; RrF2 family protein 1111986 11686062 BSVBI22_B1109 Brucella suis VBI22 RrF2 family protein YP_005109089.1 1111591 D 1112912 CDS YP_005109090.1 376279057 11686063 complement(1112047..1113249) 1 NC_016775.1 similar to GP:15160214; identified by sequence similarity; putative; cobalamin synthesis protein/P47K family protein 1113249 11686063 BSVBI22_B1110 Brucella suis VBI22 cobalamin synthesis protein/P47K family protein YP_005109090.1 1112047 R 1112912 CDS YP_005109091.1 376279058 11686065 1113274..1113414 1 NC_016775.1 hypothetical protein 1113414 11686065 BSVBI22_B1111 Brucella suis VBI22 hypothetical protein YP_005109091.1 1113274 D 1112912 CDS YP_005109092.1 376279059 11686067 complement(1113416..1114420) 1 NC_016775.1 similar to GP:15074849, and SP:P39172; identified by sequence similarity; putative; zinc ABC transporter, periplasmic zinc-binding protein 1114420 znuA 11686067 znuA Brucella suis VBI22 zinc ABC transporter, periplasmic zinc-binding protein YP_005109092.1 1113416 R 1112912 CDS YP_005109093.1 376279060 11686069 1114647..1115543 1 NC_016775.1 similar to GP:15156606; identified by sequence similarity; putative; zinc ABC transporter, ATP-binding protein 1115543 znuC 11686069 znuC Brucella suis VBI22 zinc ABC transporter, ATP-binding protein YP_005109093.1 1114647 D 1112912 CDS YP_005109094.1 376279061 11686071 1115497..1116357 1 NC_016775.1 similar to GP:15074847, and GP:17739944; identified by sequence similarity; putative; zinc ABC transporter, permease protein 1116357 znuB 11686071 znuB Brucella suis VBI22 zinc ABC transporter, permease protein YP_005109094.1 1115497 D 1112912 CDS YP_005109095.1 376279062 11686073 1116354..1116791 1 NC_016775.1 similar to GP:15156604; identified by sequence similarity; putative; FUR family transcriptional regulator 1116791 11686073 BSVBI22_B1115 Brucella suis VBI22 FUR family transcriptional regulator YP_005109095.1 1116354 D 1112912 CDS YP_005109096.1 376279063 11686074 1116918..1117253 1 NC_016775.1 hypothetical protein 1117253 11686074 BSVBI22_B1116 Brucella suis VBI22 hypothetical protein YP_005109096.1 1116918 D 1112912 CDS YP_005109097.1 376279064 11686075 complement(1117241..1117768) 1 NC_016775.1 hypothetical protein 1117768 11686075 BSVBI22_B1117 Brucella suis VBI22 hypothetical protein YP_005109097.1 1117241 R 1112912 CDS YP_005109098.1 376279065 11686076 complement(1117765..1118241) 1 NC_016775.1 similar to GP:15073620; identified by sequence similarity; putative; hypothetical protein 1118241 11686076 BSVBI22_B1118 Brucella suis VBI22 hypothetical protein YP_005109098.1 1117765 R 1112912 CDS YP_005109099.1 376279066 11686077 complement(1118382..1118972) 1 NC_016775.1 similar to GP:15073619, and GP:15073619; identified by sequence similarity; putative; hypothetical protein 1118972 11686077 BSVBI22_B1119 Brucella suis VBI22 hypothetical protein YP_005109099.1 1118382 R 1112912 CDS YP_005109100.1 376279067 11686078 complement(1119040..1119447) 1 NC_016775.1 similar to GP:3876134; identified by sequence similarity; putative; hypothetical protein 1119447 11686078 BSVBI22_B1120 Brucella suis VBI22 hypothetical protein YP_005109100.1 1119040 R 1112912 CDS YP_005109101.1 376279068 11686079 complement(1119455..1120222) 1 NC_016775.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 1120222 fliR 11686079 fliR Brucella suis VBI22 flagellar biosynthesis protein FliR YP_005109101.1 1119455 R 1112912 CDS YP_005109102.1 376279069 11686080 complement(1120238..1122409) 1 NC_016775.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1122409 flhA 11686080 flhA Brucella suis VBI22 flagellar biosynthesis protein FlhA YP_005109102.1 1120238 R 1112912 CDS YP_005109103.1 376279070 11686081 complement(1122489..1122755) 1 NC_016775.1 FliQ, with proteins FliP and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; flagellar biosynthesis protein FliQ 1122755 fliQ 11686081 fliQ Brucella suis VBI22 flagellar biosynthesis protein FliQ YP_005109103.1 1122489 R 1112912 CDS YP_005109104.1 376279071 11686082 complement(1122767..1123180) 1 NC_016775.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod modification protein 1123180 flgD 11686082 flgD Brucella suis VBI22 flagellar basal body rod modification protein YP_005109104.1 1122767 R 1112912 CDS YP_005109105.1 376279072 11686083 complement(1123177..1123635) 1 NC_016775.1 post-transcriptional repressor of flagellum biosynthesis; promotes degradation of fljK mRNA: Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis repressor FlbT 1123635 flbT 11686083 flbT Brucella suis VBI22 flagellar biosynthesis repressor FlbT YP_005109105.1 1123177 R 1112912 CDS YP_005109106.1 376279073 11686084 complement(1123637..1123981) 1 NC_016775.1 acts as an activator or flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis regulatory protein FlaF 1123981 flaF 11686084 flaF Brucella suis VBI22 flagellar biosynthesis regulatory protein FlaF YP_005109106.1 1123637 R 1112912 CDS YP_005109107.1 376279074 11686085 complement(1124113..1125159) 1 NC_016775.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar hook-associated protein FlgL 1125159 flgL 11686085 flgL Brucella suis VBI22 flagellar hook-associated protein FlgL YP_005109107.1 1124113 R 1112912 CDS YP_005109108.1 376279075 11686086 complement(1125165..1126619) 1 NC_016775.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1126619 flgK 11686086 flgK Brucella suis VBI22 flagellar hook-associated protein FlgK YP_005109108.1 1125165 R 1112912 CDS YP_005109109.1 376279076 11686087 complement(1126744..1127934) 1 NC_016775.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1127934 flgE 11686087 flgE Brucella suis VBI22 flagellar hook protein FlgE YP_005109109.1 1126744 R 1112912 CDS YP_005109110.1 376279077 11686088 complement(1128345..1129028) 1 NC_016775.1 similar to GP:15073608; identified by sequence similarity; putative; transcriptional regulator 1129028 11686088 BSVBI22_B1130 Brucella suis VBI22 transcriptional regulator YP_005109110.1 1128345 R 1112912 CDS YP_005109111.1 376279078 11686089 complement(1129356..1129928) 1 NC_016775.1 similar to GP:15073607, and GP:15073607; identified by sequence similarity; putative; hypothetical protein 1129928 11686089 BSVBI22_B1131 Brucella suis VBI22 hypothetical protein YP_005109111.1 1129356 R 1112912 CDS YP_005109112.1 376279079 11686090 complement(1129882..1131144) 1 NC_016775.1 similar to GP:15155510, and SP:Q52964; identified by sequence similarity; putative; motD-related protein 1131144 11686090 BSVBI22_B1132 Brucella suis VBI22 motD-related protein YP_005109112.1 1129882 R 1112912 CDS YP_005109113.1 376279080 11686092 complement(1132442..1133542) 1 NC_016775.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1133542 motB 11686092 motB Brucella suis VBI22 flagellar motor protein MotB YP_005109113.1 1132442 R 1112912 CDS YP_005109114.1 376279081 11686093 complement(1133539..1134219) 1 NC_016775.1 similar to GP:15155507, and GP:12057223; identified by sequence similarity; putative; hypothetical protein 1134219 11686093 BSVBI22_B1135 Brucella suis VBI22 hypothetical protein YP_005109114.1 1133539 R 1112912 CDS YP_005109115.1 376279082 11686094 complement(1134222..1135964) 1 NC_016775.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 1135964 fliF 11686094 fliF Brucella suis VBI22 flagellar MS-ring protein YP_005109115.1 1134222 R 1112912 CDS YP_005109116.1 376279083 11686095 complement(1136177..1137025) 1 NC_016775.1 similar to GP:2832232; identified by sequence similarity; putative; flagellin family protein 1137025 11686095 BSVBI22_B1137 Brucella suis VBI22 flagellin family protein YP_005109116.1 1136177 R 1112912 CDS YP_005109117.1 376279084 11686096 1137663..1147925 1 NC_016775.1 similar to GP:15162141, and GP:15162141; identified by sequence similarity; putative; outer membrane autotransporter 1147925 11686096 BSVBI22_B1138 Brucella suis VBI22 outer membrane autotransporter YP_005109117.1 1137663 D 1112912 CDS YP_005109118.1 376279085 11686097 complement(1148042..1149097) 1 NC_016775.1 hypothetical protein 1149097 11686097 BSVBI22_B1139 Brucella suis VBI22 hypothetical protein YP_005109118.1 1148042 R 1112912 CDS YP_005109119.1 376279086 11686098 1149671..1150690 1 NC_016775.1 similar to GB:X03656, GB:X03438, GB:M17706, SP:P09919, PID:1330309, PID:1330310, PID:183041, PID:183045, PID:296647, PID:31690, and PID:732764; identified by sequence similarity; putative; D-xylose ABC transporter, periplasmic D-xylose-binding protein 1150690 xylF 11686098 xylF Brucella suis VBI22 D-xylose ABC transporter, periplasmic D-xylose-binding protein YP_005109119.1 1149671 D 1112912 CDS YP_005109120.1 376279087 11686099 1150852..1152387 1 NC_016775.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 1152387 xylG 11686099 xylG Brucella suis VBI22 xylose transporter ATP-binding subunit YP_005109120.1 1150852 D 1112912 CDS YP_005109121.1 376279088 11686100 1152530..1153699 1 NC_016775.1 similar to GB:L17326, and PID:306325; identified by sequence similarity; putative; D-xylose ABC transporter, permease protein 1153699 xylH 11686100 xylH Brucella suis VBI22 D-xylose ABC transporter, permease protein YP_005109121.1 1152530 D 1112912 CDS YP_005109122.1 376279089 11686101 1153743..1153946 1 NC_016775.1 hypothetical protein 1153946 11686101 BSVBI22_B1143 Brucella suis VBI22 hypothetical protein YP_005109122.1 1153743 D 1112912 CDS YP_005109123.1 376279090 11686102 1154257..1155225 1 NC_016775.1 similar to SP:P36673, GB:U07790, PID:465107, PID:537083, GB:U00096, PID:1790689, and PID:1843456; identified by sequence similarity; putative; AraC family transcriptional regulator 1155225 11686102 BSVBI22_B1144 Brucella suis VBI22 AraC family transcriptional regulator YP_005109123.1 1154257 D 1112912 CDS YP_005109124.1 376279091 11686103 1155325..1156731 1 NC_016775.1 similar to GP:4566586; identified by sequence similarity; putative; aldehyde dehydrogenase family protein 1156731 11686103 BSVBI22_B1145 Brucella suis VBI22 aldehyde dehydrogenase family protein YP_005109124.1 1155325 D 1112912 CDS YP_005109125.1 376279092 11686104 complement(1156888..1157697) 1 NC_016775.1 similar to GB:M79446, SP:P24182, GB:M83198, PID:145175, PID:145893, PID:145896, PID:606196, GB:U00096, PID:1789654, GB:U03272, SP:P35556, and PID:437972; identified by sequence similarity; putative; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 1157697 11686104 BSVBI22_B1146 Brucella suis VBI22 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative YP_005109125.1 1156888 R 1112912 CDS YP_005109126.1 376279093 11686105 complement(1157764..1157874) 1 NC_016775.1 hypothetical protein 1157874 11686105 BSVBI22_B1147 Brucella suis VBI22 hypothetical protein YP_005109126.1 1157764 R 1112912 CDS YP_005109127.1 376279094 11686106 complement(1157915..1158718) 1 NC_016775.1 similar to GB:M98276, SP:Q04626, GB:M64046, PID:151020, PID:45360, SP:P77915, PID:1515308, GB:M13300, GB:M13301, GB:M13302, GB:M13303, GB:M13304, GB:M13305, GB:X54705, GB:X54675, GB:Z68193, SP:P04000, SP:P04001, PID:1122284, and PID:180703; identified by sequence similarity; putative; 2-keto-4-pentenoate hydratase 1158718 hpaH 11686106 hpaH Brucella suis VBI22 2-keto-4-pentenoate hydratase YP_005109127.1 1157915 R 1112912 CDS YP_005109128.1 376279095 11686107 complement(1158722..1159588) 1 NC_016775.1 similar to GP:14424793; identified by sequence similarity; putative; fumarylacetoacetate hydrolase family protein 1159588 11686107 BSVBI22_B1149 Brucella suis VBI22 fumarylacetoacetate hydrolase family protein YP_005109128.1 1158722 R 1112912 CDS YP_005109129.1 376279096 11686109 complement(1160692..1162206) 1 NC_016775.1 similar to GB:X75771, and PID:455422; identified by sequence similarity; putative; 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase 1162206 11686109 BSVBI22_B1151 Brucella suis VBI22 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase YP_005109129.1 1160692 R 1112912 CDS YP_005109130.1 376279097 11686110 complement(1162276..1162668) 1 NC_016775.1 similar to GP:10048282, and SP:Q05354; identified by sequence similarity; putative; 5-carboxymethyl-2-hydroxymuconate delta isomerase 1162668 hpcD 11686110 hpcD Brucella suis VBI22 5-carboxymethyl-2-hydroxymuconate delta isomerase YP_005109130.1 1162276 R 1112912 CDS YP_005109131.1 376279098 11686111 1162834..1163325 1 NC_016775.1 identified by match to PFAM protein family HMM PF03551; MarR family transcriptional regulator 1163325 11686111 BSVBI22_B1153 Brucella suis VBI22 MarR family transcriptional regulator YP_005109131.1 1162834 D 1112912 CDS YP_005109132.1 376279099 11686112 complement(1163315..1164334) 1 NC_016775.1 similar to GP:15162021, and GP:14026357; identified by sequence similarity; putative; hypothetical protein 1164334 11686112 BSVBI22_B1154 Brucella suis VBI22 hypothetical protein YP_005109132.1 1163315 R 1112912 CDS YP_005109133.1 376279100 11686113 complement(1164312..1165595) 1 NC_016775.1 similar to GP:14524116; identified by sequence similarity; putative; aminotransferase, class III 1165595 11686113 BSVBI22_B1155 Brucella suis VBI22 aminotransferase, class III YP_005109133.1 1164312 R 1112912 CDS YP_005109134.1 376279101 11686114 complement(1165597..1166955) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00699; hypothetical protein 1166955 11686114 BSVBI22_B1156 Brucella suis VBI22 hypothetical protein YP_005109134.1 1165597 R 1112912 CDS YP_005109135.1 376279102 11686115 complement(1166968..1167612) 1 NC_016775.1 similar to GB:M60787, and PID:150163; identified by sequence similarity; putative; HAD superfamily hydrolase 1167612 11686115 BSVBI22_B1157 Brucella suis VBI22 HAD superfamily hydrolase YP_005109135.1 1166968 R 1112912 CDS YP_005109136.1 376279103 11686116 complement(1167609..1168865) 1 NC_016775.1 similar to GP:14271863; identified by sequence similarity; putative; hypothetical protein 1168865 11686116 BSVBI22_B1158 Brucella suis VBI22 hypothetical protein YP_005109136.1 1167609 R 1112912 CDS YP_005109137.1 376279104 11686117 complement(1168865..1169647) 1 NC_016775.1 similar to GB:D12765, SP:P43268, PID:219611, and PID:602288; identified by sequence similarity; putative; IclR family transcriptional regulator 1169647 11686117 BSVBI22_B1159 Brucella suis VBI22 IclR family transcriptional regulator YP_005109137.1 1168865 R 1112912 CDS YP_005109138.1 376279105 11686118 1169897..1171390 1 NC_016775.1 similar to GP:5441757; identified by sequence similarity; putative; amino acid permease family protein 1171390 11686118 BSVBI22_B1160 Brucella suis VBI22 amino acid permease family protein YP_005109138.1 1169897 D 1112912 CDS YP_005109139.1 376279106 11686119 1171462..1172940 1 NC_016775.1 similar to GB:M11147, GB:M10119, GB:M12938, GB:X03742, GB:X03743, SP:P02792, PID:1340145, PID:1340146, PID:182514, PID:182516, PID:182518, PID:2230869, and PID:28519; identified by sequence similarity; putative; aldehyde dehydrogenase family protein 1172940 11686119 BSVBI22_B1161 Brucella suis VBI22 aldehyde dehydrogenase family protein YP_005109139.1 1171462 D 1112912 CDS YP_005109140.1 376279107 11686120 1173099..1174781 1 NC_016775.1 hypothetical protein 1174781 11686120 BSVBI22_B1162 Brucella suis VBI22 hypothetical protein YP_005109140.1 1173099 D 1112912 CDS YP_005109141.1 376279108 11686121 1174848..1176029 1 NC_016775.1 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative 1176029 11686121 BSVBI22_B1163 Brucella suis VBI22 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative YP_005109141.1 1174848 D 1112912 CDS YP_005109142.1 376279109 11686122 1176102..1176971 1 NC_016775.1 similar to GP:9716222; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, permease protein 1176971 11686122 BSVBI22_B1164 Brucella suis VBI22 branched-chain amino acid ABC transporter, permease protein YP_005109142.1 1176102 D 1112912 CDS YP_005109143.1 376279110 11686123 1176958..1178670 1 NC_016775.1 similar to GP:15156481; identified by sequence similarity; putative; branched chain amino acid ABC transporter, ATP-binding/permease protein 1178670 11686123 BSVBI22_B1165 Brucella suis VBI22 branched chain amino acid ABC transporter, ATP-binding/permease protein YP_005109143.1 1176958 D 1112912 CDS YP_005109144.1 376279111 11686124 1178667..1179371 1 NC_016775.1 similar to GB:M16442, and PID:143790; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, ATP-binding protein 1179371 11686124 BSVBI22_B1166 Brucella suis VBI22 branched-chain amino acid ABC transporter, ATP-binding protein YP_005109144.1 1178667 D 1112912 CDS YP_005109145.1 376279112 11686125 complement(1179466..1179789) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03988; hypothetical protein 1179789 11686125 BSVBI22_B1167 Brucella suis VBI22 hypothetical protein YP_005109145.1 1179466 R 1112912 CDS YP_005109146.1 376279113 11686126 complement(1179804..1180673) 1 NC_016775.1 identified by match to PFAM protein family HMM PF03741; hypothetical protein 1180673 11686126 BSVBI22_B1168 Brucella suis VBI22 hypothetical protein YP_005109146.1 1179804 R 1112912 CDS YP_005109147.1 376279114 11686127 complement(1180679..1181413) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 1181413 11686127 BSVBI22_B1169 Brucella suis VBI22 GntR family transcriptional regulator YP_005109147.1 1180679 R 1112912 CDS YP_005109148.1 376279115 11686128 complement(1181558..1182823) 1 NC_016775.1 sugar ABC transporter, periplasmic sugar-binding protein, putative 1182823 11686128 BSVBI22_B1170 Brucella suis VBI22 sugar ABC transporter, periplasmic sugar-binding protein, putative YP_005109148.1 1181558 R 1112912 CDS YP_005109149.1 376279116 11686129 complement(1182858..1183679) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00023; sugar ABC transporter, permease protein, putative 1183679 11686129 BSVBI22_B1171 Brucella suis VBI22 sugar ABC transporter, permease protein, putative YP_005109149.1 1182858 R 1112912 CDS YP_005109150.1 376279117 11686130 complement(1183690..1184649) 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR00969; sugar ABC transporter, permease protein, putative 1184649 11686130 BSVBI22_B1172 Brucella suis VBI22 sugar ABC transporter, permease protein, putative YP_005109150.1 1183690 R 1112912 CDS YP_005109151.1 376279118 11686131 complement(1184615..1185793) 1 NC_016775.1 similar to SP:Q01937; identified by sequence similarity; putative; sugar ABC transporter, ATP-binding protein, putative 1185793 11686131 BSVBI22_B1173 Brucella suis VBI22 sugar ABC transporter, ATP-binding protein, putative YP_005109151.1 1184615 R 1112912 CDS YP_005109152.1 376279119 11686132 complement(1185790..1186635) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00149; purple acid phosphatase family protein 1186635 11686132 BSVBI22_B1174 Brucella suis VBI22 purple acid phosphatase family protein YP_005109152.1 1185790 R 1112912 CDS YP_005109153.1 376279120 11686133 complement(1186910..1188397) 1 NC_016775.1 identified by match to PFAM protein family HMM PF00884; sulfatase 1188397 11686133 BSVBI22_B1175 Brucella suis VBI22 sulfatase YP_005109153.1 1186910 R 1112912 CDS YP_005109154.1 376279121 11686134 complement(1188540..1189499) 1 NC_016775.1 similar to GP:7799282, and SP:Q47537; identified by sequence similarity; putative; taurine ABC transporter, taurine-binding protein 1189499 11686134 BSVBI22_B1176 Brucella suis VBI22 taurine ABC transporter, taurine-binding protein YP_005109154.1 1188540 R 1112912 CDS YP_005109155.1 376279122 11686135 complement(1189515..1190297) 1 NC_016775.1 similar to GP:7799281; identified by sequence similarity; putative; taurine ABC transporter, ATP-binding protein 1190297 11686135 BSVBI22_B1177 Brucella suis VBI22 taurine ABC transporter, ATP-binding protein YP_005109155.1 1189515 R 1112912 CDS YP_005109156.1 376279123 11686136 complement(1190294..1191046) 1 NC_016775.1 similar to GP:7799280, and SP:Q47539; identified by sequence similarity; putative; taurine ABC transporter, permease protein 1191046 11686136 BSVBI22_B1178 Brucella suis VBI22 taurine ABC transporter, permease protein YP_005109156.1 1190294 R 1112912 CDS YP_005109157.1 376279124 11686137 complement(1191043..1192167) 1 NC_016775.1 similar to GP:2661680; identified by sequence similarity; putative; ROK family protein 1192167 11686137 BSVBI22_B1179 Brucella suis VBI22 ROK family protein YP_005109157.1 1191043 R 1112912 CDS YP_005109158.1 376279125 11686138 complement(1192423..1194408) 1 NC_016775.1 similar to GB:X73376, GB:X73377, GB:X73378, GB:X73379, GB:X73380, GB:X73381, GB:X73382, GB:X73384, GB:X73385, PID:475179, and PID:475185; identified by sequence similarity; putative; TonB dependent receptor domain-containing protein 1194408 11686138 BSVBI22_B1180 Brucella suis VBI22 TonB dependent receptor domain-containing protein YP_005109158.1 1192423 R 1112912 CDS YP_005109159.1 376279126 11686139 complement(1194405..1194527) 1 NC_016775.1 hypothetical protein 1194527 11686139 BSVBI22_B1181 Brucella suis VBI22 hypothetical protein YP_005109159.1 1194405 R 1112912 CDS YP_005109160.1 376279127 11686140 1194876..1195655 1 NC_016775.1 identified by match to PFAM protein family HMM PF00191; AraC family transcriptional regulator 1195655 11686140 BSVBI22_B1182 Brucella suis VBI22 AraC family transcriptional regulator YP_005109160.1 1194876 D 1112912 CDS YP_005109161.1 376279128 11686141 1195805..1197025 1 NC_016775.1 similar to GP:151110, and SP:P04816; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative 1197025 11686141 BSVBI22_B1183 Brucella suis VBI22 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative YP_005109161.1 1195805 D 1112912 CDS YP_005109162.1 376279129 11686142 1197227..1198090 1 NC_016775.1 similar to GB:L19201, SP:P32174, PID:304996, GB:U00096, and PID:1790325; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, permease protein 1198090 11686142 BSVBI22_B1184 Brucella suis VBI22 branched-chain amino acid ABC transporter, permease protein YP_005109162.1 1197227 D 1112912 CDS YP_005109163.1 376279130 11686144 1199031..1199765 1 NC_016775.1 similar to GB:M59757, SP:P25993, PID:143389, and GB:AL009126; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, ATP-binding protein 1199765 11686144 BSVBI22_B1186 Brucella suis VBI22 branched-chain amino acid ABC transporter, ATP-binding protein YP_005109163.1 1199031 D 1112912 CDS YP_005109164.1 376279131 11686145 1199762..1200490 1 NC_016775.1 similar to SP:P22731, GB:M16442, and PID:143790; identified by sequence similarity; putative; branched-chain amino acid ABC transporter, ATP-binding protein 1200490 11686145 BSVBI22_B1187 Brucella suis VBI22 branched-chain amino acid ABC transporter, ATP-binding protein YP_005109164.1 1199762 D 1112912 CDS YP_005109165.1 376279132 11686146 complement(1200519..1202459) 1 NC_016775.1 similar to GP:3128316, and GP:17984226; identified by sequence similarity; putative; cadmium-translocating P-type ATPase 1202459 cadA-2 11686146 cadA-2 Brucella suis VBI22 cadmium-translocating P-type ATPase YP_005109165.1 1200519 R 1112912 CDS YP_005109166.1 376279133 11686147 complement(1202739..1204091) 1 NC_016775.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1204091 hemN-2 11686147 hemN-2 Brucella suis VBI22 coproporphyrinogen III oxidase YP_005109166.1 1202739 R 1112912 CDS YP_005109167.1 376279134 11686148 complement(1204184..1204408) 1 NC_016775.1 hypothetical protein 1204408 11686148 BSVBI22_B1190 Brucella suis VBI22 hypothetical protein YP_005109167.1 1204184 R 1112912 CDS YP_005109168.1 376279135 11686149 complement(1204375..1204779) 1 NC_016775.1 hypothetical protein 1204779 11686149 BSVBI22_B1191 Brucella suis VBI22 hypothetical protein YP_005109168.1 1204375 R 1112912 CDS YP_005109169.1 376279136 11686150 1204993..1206186 1 NC_016775.1 identified by match to TIGR protein family HMM TIGR01281; replication protein RepA 1206186 repA 11686150 repA Brucella suis VBI22 replication protein RepA YP_005109169.1 1204993 D 1112912 CDS YP_005109170.1 376279137 11686151 1206251..1207237 1 NC_016775.1 similar to SP:P55392; identified by sequence similarity; putative; replication protein RepB 1207237 11686151 BSVBI22_B1193 Brucella suis VBI22 replication protein RepB YP_005109170.1 1206251 D 1112912 CDS YP_005153711.1 376279705 11729475 784..2274 1 NC_016797.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 2274 dnaA 11729475 dnaA Brucella suis VBI22 chromosomal replication initiation protein YP_005153711.1 784 D 1112912 CDS YP_005153712.1 376279706 11729477 2503..3696 1 NC_016797.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3696 dnaN 11729477 dnaN Brucella suis VBI22 DNA polymerase III subunit beta YP_005153712.1 2503 D 1112912 CDS YP_005153713.1 376279707 11729480 3878..5032 1 NC_016797.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 5032 recF 11729480 recF Brucella suis VBI22 recombination protein F YP_005153713.1 3878 D 1112912 CDS YP_005153714.1 376279708 11729483 5070..5852 1 NC_016797.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 5852 moeB 11729483 moeB Brucella suis VBI22 molybdopterin biosynthesis protein MoeB YP_005153714.1 5070 D 1112912 CDS YP_005153715.1 376279709 11729485 complement(5869..6825) 1 NC_016797.1 identified by similarity to EGAD:90750; match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase family protein 6825 11729485 BSVBI22_A0005 Brucella suis VBI22 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_005153715.1 5869 R 1112912 CDS YP_005153716.1 376279710 11729487 complement(6822..8447) 1 NC_016797.1 identified by similarity to SP:P33916; match to protein family HMM PF00005; ABC transporter ATP-binding protein 8447 11729487 BSVBI22_A0006 Brucella suis VBI22 ABC transporter ATP-binding protein YP_005153716.1 6822 R 1112912 CDS YP_005153717.1 376279711 11727350 complement(8471..9610) 1 NC_016797.1 identified by similarity to GP:17983985; match to protein family HMM PF00528; ABC transporter permease 9610 11727350 BSVBI22_A0007 Brucella suis VBI22 ABC transporter permease YP_005153717.1 8471 R 1112912 CDS YP_005153718.1 376279712 11727394 complement(9610..10707) 1 NC_016797.1 identified by similarity to SP:P33914; match to protein family HMM PF00528; ABC transporter permease 10707 11727394 BSVBI22_A0008 Brucella suis VBI22 ABC transporter permease YP_005153718.1 9610 R 1112912 CDS YP_005153719.1 376279713 11729465 complement(10819..12633) 1 NC_016797.1 identified by similarity to SP:P33913; match to protein family HMM PF00496; ABC transporter periplasmic substrate-binding protein 12633 11729465 BSVBI22_A0009 Brucella suis VBI22 ABC transporter periplasmic substrate-binding protein YP_005153719.1 10819 R 1112912 CDS YP_005153720.1 376279714 11728830 complement(12680..14548) 1 NC_016797.1 identified by match to protein family HMM PF00496; ABC transporter periplasmic substrate-binding protein 14548 11728830 BSVBI22_A0010 Brucella suis VBI22 ABC transporter periplasmic substrate-binding protein YP_005153720.1 12680 R 1112912 CDS YP_005153721.1 376279715 11728831 complement(14779..15102) 1 NC_016797.1 hypothetical protein 15102 11728831 BSVBI22_A0011 Brucella suis VBI22 hypothetical protein YP_005153721.1 14779 R 1112912 CDS YP_005153722.1 376279716 11728832 complement(15148..15348) 1 NC_016797.1 hypothetical protein 15348 11728832 BSVBI22_A0012 Brucella suis VBI22 hypothetical protein YP_005153722.1 15148 R 1112912 CDS YP_005153723.1 376279717 11728833 complement(15388..15738) 1 NC_016797.1 hypothetical protein 15738 11728833 BSVBI22_A0013 Brucella suis VBI22 hypothetical protein YP_005153723.1 15388 R 1112912 CDS YP_005153724.1 376279718 11728834 complement(16003..17109) 1 NC_016797.1 identified by similarity to SP:P02917; match to protein family HMM PF01094; branched-chain amino acid ABC transporter substrate-binding protein 17109 11728834 BSVBI22_A0014 Brucella suis VBI22 branched-chain amino acid ABC transporter substrate-binding protein YP_005153724.1 16003 R 1112912 CDS YP_005153725.1 376279719 11728835 17381..17581 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1891; hypothetical protein 17581 11728835 BSVBI22_A0015 Brucella suis VBI22 hypothetical protein YP_005153725.1 17381 D 1112912 CDS YP_005153726.1 376279720 11728836 complement(17578..18372) 1 NC_016797.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 18372 11728836 BSVBI22_A0016 Brucella suis VBI22 enoyl-CoA hydratase YP_005153726.1 17578 R 1112912 CDS YP_005153727.1 376279721 11728838 complement(19224..21245) 1 NC_016797.1 identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786; biotin carboxylase 21245 11728838 BSVBI22_A0018 Brucella suis VBI22 biotin carboxylase YP_005153727.1 19224 R 1112912 CDS YP_005153728.1 376279722 11728839 complement(21257..22864) 1 NC_016797.1 identified by match to protein family HMM PF01039; carboxyl transferase family protein 22864 11728839 BSVBI22_A0019 Brucella suis VBI22 carboxyl transferase family protein YP_005153728.1 21257 R 1112912 CDS YP_005153729.1 376279723 11728840 complement(22864..24012) 1 NC_016797.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; isovaleryl-CoA dehydrogenase 24012 ivd 11728840 ivd Brucella suis VBI22 isovaleryl-CoA dehydrogenase YP_005153729.1 22864 R 1112912 CDS YP_005153730.1 376279724 11728841 complement(24189..26177) 1 NC_016797.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase 26177 11728841 BSVBI22_A0021 Brucella suis VBI22 acetoacetyl-CoA synthetase YP_005153730.1 24189 R 1112912 CDS YP_005153731.1 376279725 11728842 complement(26362..26796) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1269; hypothetical protein 26796 11728842 BSVBI22_A0022 Brucella suis VBI22 hypothetical protein YP_005153731.1 26362 R 1112912 CDS YP_005153732.1 376279726 11728843 complement(26973..28094) 1 NC_016797.1 identified by similarity to OMNI:CC1521; match to protein family HMM PF01757; hypothetical protein 28094 11728843 BSVBI22_A0023 Brucella suis VBI22 hypothetical protein YP_005153732.1 26973 R 1112912 CDS YP_005153733.1 376279727 11728845 complement(28617..29000) 1 NC_016797.1 identified by similarity to GP:15073181; hypothetical protein 29000 11728845 BSVBI22_A0024 Brucella suis VBI22 hypothetical protein YP_005153733.1 28617 R 1112912 CDS YP_005153734.1 376279728 11728846 29385..30737 1 NC_016797.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 30737 aroA 11728846 aroA Brucella suis VBI22 3-phosphoshikimate 1-carboxyvinyltransferase YP_005153734.1 29385 D 1112912 CDS YP_005153735.1 376279729 11728847 30734..31393 1 NC_016797.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 31393 cmk 11728847 cmk Brucella suis VBI22 cytidylate kinase YP_005153735.1 30734 D 1112912 CDS YP_005153736.1 376279730 11728848 31609..33309 1 NC_016797.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 33309 rpsA 11728848 rpsA Brucella suis VBI22 30S ribosomal protein S1 YP_005153736.1 31609 D 1112912 CDS YP_005153737.1 376279731 11728849 complement(33727..34737) 1 NC_016797.1 identified by similarity to GP:15155628; match to protein family HMM PF03601; hypothetical protein 34737 11728849 BSVBI22_A0028 Brucella suis VBI22 hypothetical protein YP_005153737.1 33727 R 1112912 CDS YP_005153738.1 376279732 11728850 34853..35752 1 NC_016797.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 35752 11728850 BSVBI22_A0029 Brucella suis VBI22 LysR family transcriptional regulator YP_005153738.1 34853 D 1112912 CDS YP_005153739.1 376279733 11728851 complement(35746..36321) 1 NC_016797.1 hypothetical protein 36321 11728851 BSVBI22_A0030 Brucella suis VBI22 hypothetical protein YP_005153739.1 35746 R 1112912 CDS YP_005153740.1 376279734 11728852 complement(36357..37640) 1 NC_016797.1 transglycosylase 37640 11728852 BSVBI22_A0031 Brucella suis VBI22 transglycosylase YP_005153740.1 36357 R 1112912 CDS YP_005153741.1 376279735 11728853 complement(37656..38261) 1 NC_016797.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 38261 recR 11728853 recR Brucella suis VBI22 recombination protein RecR YP_005153741.1 37656 R 1112912 CDS YP_005153742.1 376279736 11728854 complement(38392..38715) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML4268; match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 38715 11728854 BSVBI22_A0033 Brucella suis VBI22 hypothetical protein YP_005153742.1 38392 R 1112912 CDS YP_005153743.1 376279737 11728855 complement(38740..40548) 1 NC_016797.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 40548 dnaX 11728855 dnaX Brucella suis VBI22 DNA polymerase III subunits gamma and tau YP_005153743.1 38740 R 1112912 CDS YP_005153744.1 376279738 11728856 40829..41233 1 NC_016797.1 identified by similarity to OMNI:NTL02ML4266; match to protein family HMM PF01230; hypothetical protein 41233 11728856 BSVBI22_A0035 Brucella suis VBI22 hypothetical protein YP_005153744.1 40829 D 1112912 CDS YP_005153745.1 376279739 11728857 41262..42209 1 NC_016797.1 identified by similarity to OMNI:NTL02ML4265; match to protein family HMM PF00293; MutT/nudix family protein 42209 11728857 BSVBI22_A0036 Brucella suis VBI22 MutT/nudix family protein YP_005153745.1 41262 D 1112912 CDS YP_005153746.1 376279740 11728858 complement(42210..43073) 1 NC_016797.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 43073 pheA 11728858 pheA Brucella suis VBI22 prephenate dehydratase YP_005153746.1 42210 R 1112912 CDS YP_005153747.1 376279741 11728859 complement(43162..43917) 1 NC_016797.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 43917 kdsB 11728859 kdsB Brucella suis VBI22 3-deoxy-manno-octulosonate cytidylyltransferase YP_005153747.1 43162 R 1112912 CDS YP_005153748.1 376279742 11728860 44295..44903 1 NC_016797.1 identified by similarity to EGAD:14195; match to protein family HMM PF00034; cytochrome c, membrane-bound 44903 11728860 BSVBI22_A0039 Brucella suis VBI22 cytochrome c, membrane-bound YP_005153748.1 44295 D 1112912 CDS YP_005153749.1 376279743 11728861 complement(44948..45913) 1 NC_016797.1 identified by similarity to GP:14021137; match to protein family HMM PF00994; hypothetical protein 45913 11728861 BSVBI22_A0040 Brucella suis VBI22 hypothetical protein YP_005153749.1 44948 R 1112912 CDS YP_005153750.1 376279744 11728862 45969..46277 1 NC_016797.1 hypothetical protein 46277 11728862 BSVBI22_A0041 Brucella suis VBI22 hypothetical protein YP_005153750.1 45969 D 1112912 CDS YP_005153751.1 376279745 11728863 46440..47465 1 NC_016797.1 identified by similarity to EGAD:20044; match to protein family HMM TIGR01433; ubiquinol oxidase subunit II 47465 cyoA 11728863 cyoA Brucella suis VBI22 ubiquinol oxidase subunit II YP_005153751.1 46440 D 1112912 CDS YP_005153752.1 376279746 11728864 47545..49524 1 NC_016797.1 identified by similarity to EGAD:14783; match to protein family HMM PF00115; ubiquinol oxidase subunit I 49524 qoxB 11728864 qoxB Brucella suis VBI22 ubiquinol oxidase subunit I YP_005153752.1 47545 D 1112912 CDS YP_005153753.1 376279747 11728865 49528..50157 1 NC_016797.1 identified by similarity to EGAD:13682; match to protein family HMM PF00510; ubiquinol oxidase subunit III 50157 11728865 BSVBI22_A0044 Brucella suis VBI22 ubiquinol oxidase subunit III YP_005153753.1 49528 D 1112912 CDS YP_005153754.1 376279748 11728866 50157..50522 1 NC_016797.1 identified by similarity to EGAD:20825; match to protein family HMM PF03626; ubiquinol oxidase subunit IV 50522 qoxD 11728866 qoxD Brucella suis VBI22 ubiquinol oxidase subunit IV YP_005153754.1 50157 D 1112912 CDS YP_005153755.1 376279749 11728867 complement(50519..50797) 1 NC_016797.1 hypothetical protein 50797 11728867 BSVBI22_A0046 Brucella suis VBI22 hypothetical protein YP_005153755.1 50519 R 1112912 CDS YP_005153756.1 376279750 11728868 50973..51560 1 NC_016797.1 identified by similarity to GP:3511221; hypothetical protein 51560 11728868 BSVBI22_A0047 Brucella suis VBI22 hypothetical protein YP_005153756.1 50973 D 1112912 CDS YP_005153757.1 376279751 11728869 52156..54075 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1304; match to protein family HMM PF01103; hypothetical protein 54075 11728869 BSVBI22_A0048 Brucella suis VBI22 hypothetical protein YP_005153757.1 52156 D 1112912 CDS YP_005153758.1 376279752 11728870 54264..58811 1 NC_016797.1 identified by similarity to GP:15076022; match to protein family HMM PF04357; match to protein family HMM TIGR01612; hypothetical protein 58811 11728870 BSVBI22_A0049 Brucella suis VBI22 hypothetical protein YP_005153758.1 54264 D 1112912 CDS YP_005153759.1 376279753 11728871 58956..59681 1 NC_016797.1 identified by similarity to GP:15160041; match to protein family HMM PF03734; match to protein family HMM TIGR01409; putative lipoprotein 59681 11728871 BSVBI22_A0050 Brucella suis VBI22 putative lipoprotein YP_005153759.1 58956 D 1112912 CDS YP_005153760.1 376279754 11728872 complement(59732..59947) 1 NC_016797.1 hypothetical protein 59947 11728872 BSVBI22_A0051 Brucella suis VBI22 hypothetical protein YP_005153760.1 59732 R 1112912 CDS YP_005153761.1 376279755 11728873 complement(60017..60520) 1 NC_016797.1 hypothetical protein 60520 11728873 BSVBI22_A0052 Brucella suis VBI22 hypothetical protein YP_005153761.1 60017 R 1112912 CDS YP_005153762.1 376279756 11728874 complement(60857..61063) 1 NC_016797.1 hypothetical protein 61063 11728874 BSVBI22_A0053 Brucella suis VBI22 hypothetical protein YP_005153762.1 60857 R 1112912 CDS YP_005153763.1 376279757 11728875 complement(61074..62078) 1 NC_016797.1 identified by similarity to GP:15074483; match to protein family HMM PF04314; hypothetical protein 62078 11728875 BSVBI22_A0054 Brucella suis VBI22 hypothetical protein YP_005153763.1 61074 R 1112912 CDS YP_005153764.1 376279758 11728876 complement(62213..62611) 1 NC_016797.1 hypothetical protein 62611 11728876 BSVBI22_A0055 Brucella suis VBI22 hypothetical protein YP_005153764.1 62213 R 1112912 CDS YP_005153765.1 376279759 11728877 complement(62856..63251) 1 NC_016797.1 identified by match to protein family HMM PF00903; glyoxalase family protein 63251 11728877 BSVBI22_A0056 Brucella suis VBI22 glyoxalase family protein YP_005153765.1 62856 R 1112912 CDS YP_005153766.1 376279760 11728878 63448..64611 1 NC_016797.1 identified by match to protein family HMM PF01883; mrp-related protein 64611 11728878 BSVBI22_A0057 Brucella suis VBI22 mrp-related protein YP_005153766.1 63448 D 1112912 CDS YP_005153767.1 376279761 11728879 complement(64776..66407) 1 NC_016797.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 66407 pgm 11728879 pgm Brucella suis VBI22 phosphoglucomutase YP_005153767.1 64776 R 1112912 CDS YP_005153768.1 376279762 11728880 complement(66463..66648) 1 NC_016797.1 hypothetical protein 66648 11728880 BSVBI22_A0059 Brucella suis VBI22 hypothetical protein YP_005153768.1 66463 R 1112912 CDS YP_005153769.1 376279763 11728881 complement(66623..67516) 1 NC_016797.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 67516 11728881 BSVBI22_A0060 Brucella suis VBI22 LysR family transcriptional regulator YP_005153769.1 66623 R 1112912 CDS YP_005153770.1 376279764 11728882 67641..68564 1 NC_016797.1 dienelactone hydrolase domain-containing protein 68564 11728882 BSVBI22_A0061 Brucella suis VBI22 dienelactone hydrolase domain-containing protein YP_005153770.1 67641 D 1112912 CDS YP_005153771.1 376279765 11728883 68637..69335 1 NC_016797.1 identified by similarity to GP:11066210; putative fructose transport system kinase 69335 frcK 11728883 frcK Brucella suis VBI22 putative fructose transport system kinase YP_005153771.1 68637 D 1112912 CDS YP_005153772.1 376279766 11728884 69435..70124 1 NC_016797.1 identified by match to protein family HMM PF01557; fumarylacetoacetate hydrolase family protein 70124 11728884 BSVBI22_A0063 Brucella suis VBI22 fumarylacetoacetate hydrolase family protein YP_005153772.1 69435 D 1112912 CDS YP_005153773.1 376279767 11728885 70144..70335 1 NC_016797.1 identified by similarity to GP:15073555; hypothetical protein 70335 11728885 BSVBI22_A0064 Brucella suis VBI22 hypothetical protein YP_005153773.1 70144 D 1112912 CDS YP_005153774.1 376279768 11728886 70397..70612 1 NC_016797.1 hypothetical protein 70612 11728886 BSVBI22_A0065 Brucella suis VBI22 hypothetical protein YP_005153774.1 70397 D 1112912 CDS YP_005153775.1 376279769 11728887 70778..70966 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3554; hypothetical protein 70966 11728887 BSVBI22_A0066 Brucella suis VBI22 hypothetical protein YP_005153775.1 70778 D 1112912 CDS YP_005153776.1 376279770 11728888 70981..71844 1 NC_016797.1 identified by match to protein family HMM PF01464; transglycosylase 71844 11728888 BSVBI22_A0067 Brucella suis VBI22 transglycosylase YP_005153776.1 70981 D 1112912 CDS YP_005153777.1 376279771 11728889 72030..72686 1 NC_016797.1 identified by similarity to EGAD:38000; match to protein family HMM PF03006; hemolysin III family channel protein 72686 11728889 BSVBI22_A0068 Brucella suis VBI22 hemolysin III family channel protein YP_005153777.1 72030 D 1112912 CDS YP_005153778.1 376279772 11728890 complement(72827..76060) 1 NC_016797.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase.; error-prone DNA polymerase 76060 dnaE2 11728890 dnaE2 Brucella suis VBI22 error-prone DNA polymerase YP_005153778.1 72827 R 1112912 CDS YP_005153779.1 376279773 11728891 complement(76060..77511) 1 NC_016797.1 identified by similarity to GP:14523587; hypothetical protein 77511 11728891 BSVBI22_A0070 Brucella suis VBI22 hypothetical protein YP_005153779.1 76060 R 1112912 CDS YP_005153780.1 376279774 11728892 complement(77537..78400) 1 NC_016797.1 identified by similarity to GP:15076199; hypothetical protein 78400 11728892 BSVBI22_A0071 Brucella suis VBI22 hypothetical protein YP_005153780.1 77537 R 1112912 CDS YP_005153781.1 376279775 11728893 78919..81141 1 NC_016797.1 identified by similarity to SP:P10858; match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662; outer membrane protein 81141 11728893 BSVBI22_A0072 Brucella suis VBI22 outer membrane protein YP_005153781.1 78919 D 1112912 CDS YP_005153782.1 376279776 11728894 81350..81898 1 NC_016797.1 identified by similarity to GP:15073388; hypothetical protein 81898 11728894 BSVBI22_A0073 Brucella suis VBI22 hypothetical protein YP_005153782.1 81350 D 1112912 CDS YP_005153783.1 376279777 11728895 complement(81977..83197) 1 NC_016797.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 83197 argG 11728895 argG Brucella suis VBI22 argininosuccinate synthase YP_005153783.1 81977 R 1112912 CDS YP_005153784.1 376279778 11728897 complement(84047..84550) 1 NC_016797.1 hypothetical protein 84550 11728897 BSVBI22_A0076 Brucella suis VBI22 hypothetical protein YP_005153784.1 84047 R 1112912 CDS YP_005153785.1 376279779 11728898 complement(84584..85819) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3355; match to protein family HMM PF04055; match to protein family HMM TIGR00048; hypothetical protein 85819 11728898 BSVBI22_A0077 Brucella suis VBI22 hypothetical protein YP_005153785.1 84584 R 1112912 CDS YP_005153786.1 376279780 11728899 85763..85954 1 NC_016797.1 hypothetical protein 85954 11728899 BSVBI22_A0078 Brucella suis VBI22 hypothetical protein YP_005153786.1 85763 D 1112912 CDS YP_005153787.1 376279781 11728900 85939..86133 1 NC_016797.1 hypothetical protein 86133 11728900 BSVBI22_A0079 Brucella suis VBI22 hypothetical protein YP_005153787.1 85939 D 1112912 CDS YP_005153788.1 376279782 11728901 complement(86079..86582) 1 NC_016797.1 identified by similarity to GP:15076241; hypothetical protein 86582 11728901 BSVBI22_A0080 Brucella suis VBI22 hypothetical protein YP_005153788.1 86079 R 1112912 CDS YP_005153789.1 376279783 11728902 complement(87014..87397) 1 NC_016797.1 identified by similarity to GP:15076242; hypothetical protein 87397 11728902 BSVBI22_A0081 Brucella suis VBI22 hypothetical protein YP_005153789.1 87014 R 1112912 CDS YP_005153790.1 376279784 11728903 complement(87485..87778) 1 NC_016797.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase 87778 phhB 11728903 phhB Brucella suis VBI22 pterin-4-alpha-carbinolamine dehydratase YP_005153790.1 87485 R 1112912 CDS YP_005153791.1 376279785 11728904 88005..88610 1 NC_016797.1 identified by match to protein family HMM PF01451; phosphotyrosine protein phosphatase 88610 11728904 BSVBI22_A0083 Brucella suis VBI22 phosphotyrosine protein phosphatase YP_005153791.1 88005 D 1112912 CDS YP_005153792.1 376279786 11728905 complement(88520..89110) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3347; hypothetical protein 89110 11728905 BSVBI22_A0084 Brucella suis VBI22 hypothetical protein YP_005153792.1 88520 R 1112912 CDS YP_005153793.1 376279787 11728906 complement(89291..90016) 1 NC_016797.1 identified by match to protein family HMM PF00657; lipase/acylhydrolase domain-containing protein 90016 11728906 BSVBI22_A0085 Brucella suis VBI22 lipase/acylhydrolase domain-containing protein YP_005153793.1 89291 R 1112912 CDS YP_005153794.1 376279788 11728907 90163..90891 1 NC_016797.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 90891 11728907 BSVBI22_A0086 Brucella suis VBI22 ABC transporter ATP-binding protein YP_005153794.1 90163 D 1112912 CDS YP_005153795.1 376279789 11728908 90888..93437 1 NC_016797.1 identified by match to protein family HMM PF02687; ABC transporter permease 93437 11728908 BSVBI22_A0087 Brucella suis VBI22 ABC transporter permease YP_005153795.1 90888 D 1112912 CDS YP_005153796.1 376279790 11728909 93671..94408 1 NC_016797.1 identified by similarity to GP:15076248; match to protein family HMM PF01027; hypothetical protein 94408 11728909 BSVBI22_A0088 Brucella suis VBI22 hypothetical protein YP_005153796.1 93671 D 1112912 CDS YP_005153797.1 376279791 11728910 94523..95062 1 NC_016797.1 identified by similarity to EGAD:8993; match to protein family HMM PF00583; phosphinothricin N-acetyltransferase 95062 pat 11728910 pat Brucella suis VBI22 phosphinothricin N-acetyltransferase YP_005153797.1 94523 D 1112912 CDS YP_005153798.1 376279792 11728911 complement(95082..95483) 1 NC_016797.1 identified by similarity to GP:15076253; hypothetical protein 95483 11728911 BSVBI22_A0090 Brucella suis VBI22 hypothetical protein YP_005153798.1 95082 R 1112912 CDS YP_005153799.1 376279793 11728912 complement(96033..96767) 1 NC_016797.1 identified by similarity to GP:15076254; hypothetical protein 96767 11728912 BSVBI22_A0091 Brucella suis VBI22 hypothetical protein YP_005153799.1 96033 R 1112912 CDS YP_005153800.1 376279794 11728913 complement(96920..97060) 1 NC_016797.1 hypothetical protein 97060 11728913 BSVBI22_A0092 Brucella suis VBI22 hypothetical protein YP_005153800.1 96920 R 1112912 CDS YP_005153801.1 376279795 11728914 complement(97044..99731) 1 NC_016797.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 99731 acnA 11728914 acnA Brucella suis VBI22 aconitate hydratase YP_005153801.1 97044 R 1112912 CDS YP_005153802.1 376279796 11728915 100075..100722 1 NC_016797.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 100722 ccmA 11728915 ccmA Brucella suis VBI22 cytochrome c biogenesis protein CcmA YP_005153802.1 100075 D 1112912 CDS YP_005153803.1 376279797 11728916 100722..101387 1 NC_016797.1 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190; heme exporter protein CcmB 101387 ccmB 11728916 ccmB Brucella suis VBI22 heme exporter protein CcmB YP_005153803.1 100722 D 1112912 CDS YP_005153804.1 376279798 11728917 101445..102230 1 NC_016797.1 identified by similarity to SP:P30962; match to protein family HMM PF01578; match to protein family HMM TIGR01191; heme exporter protein CcmC 102230 ccmC 11728917 ccmC Brucella suis VBI22 heme exporter protein CcmC YP_005153804.1 101445 D 1112912 CDS YP_005153805.1 376279799 11728918 102227..102400 1 NC_016797.1 identified by similarity to EGAD:15659; match to protein family HMM PF04995; heme exporter protein D 102400 11728918 BSVBI22_A0097 Brucella suis VBI22 heme exporter protein D YP_005153805.1 102227 D 1112912 CDS YP_005153806.1 376279800 11728919 102397..103008 1 NC_016797.1 identified by match to protein family HMM TIGR00385; thioredoxin family thiol:disulfide interchange protein 103008 cycY 11728919 cycY Brucella suis VBI22 thioredoxin family thiol:disulfide interchange protein YP_005153806.1 102397 D 1112912 CDS YP_005153807.1 376279801 11728920 complement(103257..105092) 1 NC_016797.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 105092 ilvD 11728920 ilvD Brucella suis VBI22 dihydroxy-acid dehydratase YP_005153807.1 103257 R 1112912 CDS YP_005153808.1 376279802 11728921 105274..105411 1 NC_016797.1 hypothetical protein 105411 11728921 BSVBI22_A0100 Brucella suis VBI22 hypothetical protein YP_005153808.1 105274 D 1112912 CDS YP_005153809.1 376279803 11728922 complement(105492..105845) 1 NC_016797.1 identified by similarity to GP:15157523; hypothetical protein 105845 11728922 BSVBI22_A0101 Brucella suis VBI22 hypothetical protein YP_005153809.1 105492 R 1112912 CDS YP_005153810.1 376279804 11728923 complement(105950..106327) 1 NC_016797.1 identified by similarity to OMNI:CC3015; match to protein family HMM PF00072; response regulator 106327 11728923 BSVBI22_A0102 Brucella suis VBI22 response regulator YP_005153810.1 105950 R 1112912 CDS YP_005153811.1 376279805 11728924 complement(106502..106738) 1 NC_016797.1 transcriptional regulator 106738 11728924 BSVBI22_A0103 Brucella suis VBI22 transcriptional regulator YP_005153811.1 106502 R 1112912 CDS YP_005153812.1 376279806 11728925 107391..107795 1 NC_016797.1 identified by similarity to GP:15155891; hypothetical protein 107795 11728925 BSVBI22_A0104 Brucella suis VBI22 hypothetical protein YP_005153812.1 107391 D 1112912 CDS YP_005153813.1 376279807 11728926 complement(107881..108585) 1 NC_016797.1 hypothetical protein 108585 11728926 BSVBI22_A0105 Brucella suis VBI22 hypothetical protein YP_005153813.1 107881 R 1112912 CDS YP_005153814.1 376279808 11728927 108657..109475 1 NC_016797.1 identified by similarity to EGAD:8060; hypothetical protein 109475 11728927 BSVBI22_A0106 Brucella suis VBI22 hypothetical protein YP_005153814.1 108657 D 1112912 CDS YP_005153815.1 376279809 11728928 109753..110781 1 NC_016797.1 identified by similarity to GP:17983880; match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate ABC transporter substrate-binding protein 110781 11728928 BSVBI22_A0107 Brucella suis VBI22 sulfate ABC transporter substrate-binding protein YP_005153815.1 109753 D 1112912 CDS YP_005153816.1 376279810 11728929 110876..111742 1 NC_016797.1 identified by similarity to SP:Q01895; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate ABC transporter, permease protein 111742 11728929 BSVBI22_A0108 Brucella suis VBI22 sulfate ABC transporter, permease protein YP_005153816.1 110876 D 1112912 CDS YP_005153817.1 376279811 11728930 111732..112598 1 NC_016797.1 identified by similarity to SP:P16702; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02140; sulfate ABC transporter, permease protein 112598 cysW-1 11728930 cysW-1 Brucella suis VBI22 sulfate ABC transporter, permease protein YP_005153817.1 111732 D 1112912 CDS YP_005153818.1 376279812 11728931 112696..113775 1 NC_016797.1 identified by similarity to SP:P14788; match to protein family HMM PF00005; match to protein family HMM TIGR00968; sulfate ABC transporter ATP-binding protein 113775 11728931 BSVBI22_A0110 Brucella suis VBI22 sulfate ABC transporter ATP-binding protein YP_005153818.1 112696 D 1112912 CDS YP_005153819.1 376279813 11727582 114566..122764 1 NC_016797.1 identified by similarity to GP:3551791; match to protein family HMM TIGR01612; cyclic beta 1-2 glucan synthetase 122764 11727582 BSVBI22_A0111 Brucella suis VBI22 cyclic beta 1-2 glucan synthetase YP_005153819.1 114566 D 1112912 CDS YP_005153820.1 376279814 11727583 122854..124158 1 NC_016797.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 124158 pncB 11727583 pncB Brucella suis VBI22 nicotinate phosphoribosyltransferase YP_005153820.1 122854 D 1112912 CDS YP_005153821.1 376279815 11727584 complement(124200..125030) 1 NC_016797.1 identified by similarity to EGAD:38480; match to protein family HMM PF02567; match to protein family HMM TIGR00654; PhzF family phenazine biosynthesis protein 125030 11727584 BSVBI22_A0113 Brucella suis VBI22 PhzF family phenazine biosynthesis protein YP_005153821.1 124200 R 1112912 CDS YP_005153822.1 376279816 11727585 complement(125140..125928) 1 NC_016797.1 identified by similarity to GP:15075131; hypothetical protein 125928 11727585 BSVBI22_A0114 Brucella suis VBI22 hypothetical protein YP_005153822.1 125140 R 1112912 CDS YP_005153823.1 376279817 11727586 complement(125951..126877) 1 NC_016797.1 identified by similarity to EGAD:15614; match to protein family HMM PF00294; fructokinase 126877 cscK 11727586 cscK Brucella suis VBI22 fructokinase YP_005153823.1 125951 R 1112912 CDS YP_005153824.1 376279818 11727587 complement(126968..127774) 1 NC_016797.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 127774 11727587 BSVBI22_A0116 Brucella suis VBI22 short chain dehydrogenase/reductase family oxidoreductase YP_005153824.1 126968 R 1112912 CDS YP_005153825.1 376279819 11727588 complement(127895..130186) 1 NC_016797.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; 1A family penicillin-binding protein 130186 11727588 BSVBI22_A0117 Brucella suis VBI22 1A family penicillin-binding protein YP_005153825.1 127895 R 1112912 CDS YP_005153826.1 376279820 11727589 complement(130391..131083) 1 NC_016797.1 outer membrane protein 131083 11727589 BSVBI22_A0118 Brucella suis VBI22 outer membrane protein YP_005153826.1 130391 R 1112912 CDS YP_005153827.1 376279821 11727590 complement(131351..132037) 1 NC_016797.1 identified by similarity to EGAD:151783; outer membrane protein 132037 11727590 BSVBI22_A0119 Brucella suis VBI22 outer membrane protein YP_005153827.1 131351 R 1112912 CDS YP_005153828.1 376279822 11727591 complement(132269..132886) 1 NC_016797.1 identified by match to protein family HMM PF01612; 3'-5' exonuclease 132886 11727591 BSVBI22_A0120 Brucella suis VBI22 3'-5' exonuclease YP_005153828.1 132269 R 1112912 CDS YP_005153829.1 376279823 11727592 complement(132925..134340) 1 NC_016797.1 identified by match to protein family HMM PF01546; hypothetical protein 134340 11727592 BSVBI22_A0121 Brucella suis VBI22 hypothetical protein YP_005153829.1 132925 R 1112912 CDS YP_005153830.1 376279824 11727593 134493..134819 1 NC_016797.1 hypothetical protein 134819 11727593 BSVBI22_A0122 Brucella suis VBI22 hypothetical protein YP_005153830.1 134493 D 1112912 CDS YP_005153831.1 376279825 11727594 134901..137840 1 NC_016797.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 137840 polA 11727594 polA Brucella suis VBI22 DNA polymerase I YP_005153831.1 134901 D 1112912 CDS YP_005153832.1 376279826 11727595 137982..139862 1 NC_016797.1 identified by similarity to SP:P23304; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; DEAD/DEAH box helicase 139862 11727595 BSVBI22_A0124 Brucella suis VBI22 DEAD/DEAH box helicase YP_005153832.1 137982 D 1112912 CDS YP_005153833.1 376279827 11727596 complement(139958..142390) 1 NC_016797.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 142390 gyrB 11727596 gyrB Brucella suis VBI22 DNA gyrase subunit B YP_005153833.1 139958 R 1112912 CDS YP_005153834.1 376279828 11727597 complement(142450..142617) 1 NC_016797.1 hypothetical protein 142617 11727597 BSVBI22_A0126 Brucella suis VBI22 hypothetical protein YP_005153834.1 142450 R 1112912 CDS YP_005153835.1 376279829 11727598 complement(142722..143477) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5595; match to protein family HMM PF00756; esterase 143477 11727598 BSVBI22_A0127 Brucella suis VBI22 esterase YP_005153835.1 142722 R 1112912 CDS YP_005153836.1 376279830 11727599 complement(143566..144222) 1 NC_016797.1 identified by similarity to GP:14021760; hypothetical protein 144222 11727599 BSVBI22_A0128 Brucella suis VBI22 hypothetical protein YP_005153836.1 143566 R 1112912 CDS YP_005153837.1 376279831 11727600 complement(144222..144689) 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 144689 11727600 BSVBI22_A0129 Brucella suis VBI22 acetyltransferase YP_005153837.1 144222 R 1112912 CDS YP_005153838.1 376279832 11727602 complement(145835..146119) 1 NC_016797.1 identified by similarity to EGAD:97446; match to protein family HMM PF02583; hypothetical protein 146119 11727602 BSVBI22_A0131 Brucella suis VBI22 hypothetical protein YP_005153838.1 145835 R 1112912 CDS YP_005153839.1 376279833 11727604 148795..150087 1 NC_016797.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 150087 11727604 BSVBI22_A0133 Brucella suis VBI22 sensor histidine kinase YP_005153839.1 148795 D 1112912 CDS YP_005153840.1 376279834 11727605 150179..150490 1 NC_016797.1 identified by similarity to EGAD:46813; IS711, transposase orfA 150490 11727605 BSVBI22_A0134 Brucella suis VBI22 IS711, transposase orfA YP_005153840.1 150179 D 1112912 CDS YP_005153841.1 376279835 11727606 150522..150914 1 NC_016797.1 identified by similarity to PIR:PN0685; match to protein family HMM PF01609; IS711, transposase orfB 150914 11727606 BSVBI22_A0135 Brucella suis VBI22 IS711, transposase orfB YP_005153841.1 150522 D 1112912 CDS YP_005153842.1 376279836 11727607 150980..151318 1 NC_016797.1 hypothetical protein 151318 11727607 BSVBI22_A0136 Brucella suis VBI22 hypothetical protein YP_005153842.1 150980 D 1112912 CDS YP_005153843.1 376279837 11727608 151514..152077 1 NC_016797.1 identified by match to protein family HMM PF00072; match to protein family HMM TIGR01199; DNA-binding response regulator 152077 11727608 BSVBI22_A0137 Brucella suis VBI22 DNA-binding response regulator YP_005153843.1 151514 D 1112912 CDS YP_005153844.1 376279838 11727609 complement(152083..152577) 1 NC_016797.1 identified by similarity to GP:15154914; hypothetical protein 152577 11727609 BSVBI22_A0138 Brucella suis VBI22 hypothetical protein YP_005153844.1 152083 R 1112912 CDS YP_005153845.1 376279839 11727610 152846..153466 1 NC_016797.1 identified by similarity to GP:9392598; match to protein family HMM PF03734; putative lipoprotein 153466 11727610 BSVBI22_A0139 Brucella suis VBI22 putative lipoprotein YP_005153845.1 152846 D 1112912 CDS YP_005153846.1 376279840 11727611 complement(153556..154128) 1 NC_016797.1 identified by match to protein family HMM PF01106; NifU-like protein 154128 11727611 BSVBI22_A0140 Brucella suis VBI22 NifU-like protein YP_005153846.1 153556 R 1112912 CDS YP_005153847.1 376279841 11727612 complement(154237..154725) 1 NC_016797.1 identified by similarity to GP:15155260; match to protein family HMM PF00582; hypothetical protein 154725 11727612 BSVBI22_A0141 Brucella suis VBI22 hypothetical protein YP_005153847.1 154237 R 1112912 CDS YP_005153848.1 376279842 11727613 complement(154783..155850) 1 NC_016797.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 155850 trpS 11727613 trpS Brucella suis VBI22 tryptophanyl-tRNA synthetase YP_005153848.1 154783 R 1112912 CDS YP_005153849.1 376279843 11727614 complement(155947..157536) 1 NC_016797.1 identified by similarity to SP:P56882; match to protein family HMM PF03023; match to protein family HMM TIGR01695; virulence factor MviN 157536 mviN 11727614 mviN Brucella suis VBI22 virulence factor MviN YP_005153849.1 155947 R 1112912 CDS YP_005153850.1 376279844 11727615 complement(157550..160354) 1 NC_016797.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 160354 11727615 BSVBI22_A0144 Brucella suis VBI22 PII uridylyl-transferase YP_005153850.1 157550 R 1112912 CDS YP_005153851.1 376279845 11727616 160420..160515 1 NC_016797.1 hypothetical protein 160515 11727616 BSVBI22_A0145 Brucella suis VBI22 hypothetical protein YP_005153851.1 160420 D 1112912 CDS YP_005153852.1 376279846 11727618 162926..165658 1 NC_016797.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 165658 mutS 11727618 mutS Brucella suis VBI22 DNA mismatch repair protein MutS YP_005153852.1 162926 D 1112912 CDS YP_005153853.1 376279847 11727619 complement(165964..166809) 1 NC_016797.1 identified by similarity to GP:15073322; hypothetical protein 166809 11727619 BSVBI22_A0148 Brucella suis VBI22 hypothetical protein YP_005153853.1 165964 R 1112912 CDS YP_005153854.1 376279848 11727620 complement(167132..167614) 1 NC_016797.1 identified by similarity to EGAD:21383; match to protein family HMM PF01252; match to protein family HMM TIGR00077; lipoprotein signal peptidase 167614 lspA 11727620 lspA Brucella suis VBI22 lipoprotein signal peptidase YP_005153854.1 167132 R 1112912 CDS YP_005153855.1 376279849 11727621 complement(167616..168509) 1 NC_016797.1 identified by match to protein family HMM PF00588; RNA methyltransferase 168509 11727621 BSVBI22_A0150 Brucella suis VBI22 RNA methyltransferase YP_005153855.1 167616 R 1112912 CDS YP_005153856.1 376279850 11727622 complement(168506..169651) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2473; SAM dependent methyltransferase 169651 11727622 BSVBI22_A0151 Brucella suis VBI22 SAM dependent methyltransferase YP_005153856.1 168506 R 1112912 CDS YP_005153857.1 376279851 11727623 complement(169764..170087) 1 NC_016797.1 identified by similarity to GP:15073316; hypothetical protein 170087 11727623 BSVBI22_A0152 Brucella suis VBI22 hypothetical protein YP_005153857.1 169764 R 1112912 CDS YP_005153858.1 376279852 11727624 complement(170097..170381) 1 NC_016797.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 170381 ihfB 11727624 ihfB Brucella suis VBI22 integration host factor subunit beta YP_005153858.1 170097 R 1112912 CDS YP_005153859.1 376279853 11727625 complement(170428..171423) 1 NC_016797.1 identified by match to protein family HMM PF01343; match to protein family HMM TIGR00706; signal peptide peptidase SppA 171423 sppA 11727625 sppA Brucella suis VBI22 signal peptide peptidase SppA YP_005153859.1 170428 R 1112912 CDS YP_005153860.1 376279854 11727626 171942..172595 1 NC_016797.1 identified by similarity to GP:15155241; hypothetical protein 172595 11727626 BSVBI22_A0155 Brucella suis VBI22 hypothetical protein YP_005153860.1 171942 D 1112912 CDS YP_005153861.1 376279855 11727627 172918..173532 1 NC_016797.1 identified by similarity to GP:15155240; match to protein family HMM PF03968; hypothetical protein 173532 11727627 BSVBI22_A0156 Brucella suis VBI22 hypothetical protein YP_005153861.1 172918 D 1112912 CDS YP_005153862.1 376279856 11727628 173544..174377 1 NC_016797.1 identified by similarity to GP:17983823; match to protein family HMM PF00005; ABC transporter ATP-binding protein 174377 11727628 BSVBI22_A0157 Brucella suis VBI22 ABC transporter ATP-binding protein YP_005153862.1 173544 D 1112912 CDS YP_005153863.1 376279857 11727629 174673..176175 1 NC_016797.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 176175 rpoN 11727629 rpoN Brucella suis VBI22 RNA polymerase factor sigma-54 YP_005153863.1 174673 D 1112912 CDS YP_005153864.1 376279858 11727630 complement(176324..176689) 1 NC_016797.1 hypothetical protein 176689 11727630 BSVBI22_A0159 Brucella suis VBI22 hypothetical protein YP_005153864.1 176324 R 1112912 CDS YP_005153865.1 376279859 11727631 176925..177518 1 NC_016797.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741; ribosomal subunit interface protein 177518 yfiA 11727631 yfiA Brucella suis VBI22 ribosomal subunit interface protein YP_005153865.1 176925 D 1112912 CDS YP_005153866.1 376279860 11727632 177621..178085 1 NC_016797.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR01419; PTS system nitrogen regulatory protein IIA 178085 ptsN 11727632 ptsN Brucella suis VBI22 PTS system nitrogen regulatory protein IIA YP_005153866.1 177621 D 1112912 CDS YP_005153867.1 376279861 11727633 complement(178166..178411) 1 NC_016797.1 identified by similarity to GP:15073342; hypothetical protein 178411 11727633 BSVBI22_A0162 Brucella suis VBI22 hypothetical protein YP_005153867.1 178166 R 1112912 CDS YP_005153868.1 376279862 11727634 complement(178517..178999) 1 NC_016797.1 identified by similarity to OMNI:CC3592; match to protein family HMM PF00011; HSP20 family protein 178999 11727634 BSVBI22_A0163 Brucella suis VBI22 HSP20 family protein YP_005153868.1 178517 R 1112912 CDS YP_005153869.1 376279863 11727635 complement(179030..179242) 1 NC_016797.1 hypothetical protein 179242 11727635 BSVBI22_A0164 Brucella suis VBI22 hypothetical protein YP_005153869.1 179030 R 1112912 CDS YP_005153870.1 376279864 11727636 complement(179211..179708) 1 NC_016797.1 identified by similarity to GP:15158767; hypothetical protein 179708 11727636 BSVBI22_A0165 Brucella suis VBI22 hypothetical protein YP_005153870.1 179211 R 1112912 CDS YP_005153871.1 376279865 11727637 179813..180559 1 NC_016797.1 identified by similarity to EGAD:18451; match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III 180559 nth 11727637 nth Brucella suis VBI22 endonuclease III YP_005153871.1 179813 D 1112912 CDS YP_005153872.1 376279866 11727638 complement(180600..181313) 1 NC_016797.1 putative role in sulfur assimilation; CysZ-like protein 181313 11727638 BSVBI22_A0167 Brucella suis VBI22 CysZ-like protein YP_005153872.1 180600 R 1112912 CDS YP_005153873.1 376279867 11727639 complement(181310..181570) 1 NC_016797.1 hypothetical protein 181570 11727639 BSVBI22_A0168 Brucella suis VBI22 hypothetical protein YP_005153873.1 181310 R 1112912 CDS YP_005153874.1 376279868 11727640 181573..182565 1 NC_016797.1 identified by match to protein family HMM PF00294; carbohydrate kinase 182565 11727640 BSVBI22_A0169 Brucella suis VBI22 carbohydrate kinase YP_005153874.1 181573 D 1112912 CDS YP_005153875.1 376279869 11727641 complement(182584..183240) 1 NC_016797.1 identified by similarity to GP:15155036; match to protein family HMM PF03458; hypothetical protein 183240 11727641 BSVBI22_A0170 Brucella suis VBI22 hypothetical protein YP_005153875.1 182584 R 1112912 CDS YP_005153876.1 376279870 11727642 complement(183373..184065) 1 NC_016797.1 identified by match to protein family HMM PF01025; heat shock protein GrpE 184065 grpE 11727642 grpE Brucella suis VBI22 heat shock protein GrpE YP_005153876.1 183373 R 1112912 CDS YP_005153877.1 376279871 11727643 complement(184171..185295) 1 NC_016797.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 185295 hrcA 11727643 hrcA Brucella suis VBI22 heat-inducible transcription repressor YP_005153877.1 184171 R 1112912 CDS YP_005153878.1 376279872 11727644 185463..186179 1 NC_016797.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 186179 rph 11727644 rph Brucella suis VBI22 ribonuclease PH YP_005153878.1 185463 D 1112912 CDS YP_005153879.1 376279873 11727645 186353..186757 1 NC_016797.1 identified by match to protein family HMM PF00903; glyoxalase family protein 186757 11727645 BSVBI22_A0174 Brucella suis VBI22 glyoxalase family protein YP_005153879.1 186353 D 1112912 CDS YP_005153880.1 376279874 11727646 186760..187422 1 NC_016797.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 187422 11727646 BSVBI22_A0175 Brucella suis VBI22 putative deoxyribonucleotide triphosphate pyrophosphatase YP_005153880.1 186760 D 1112912 CDS YP_005153881.1 376279875 11727647 187476..188633 1 NC_016797.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 188633 11727647 BSVBI22_A0176 Brucella suis VBI22 coproporphyrinogen III oxidase YP_005153881.1 187476 D 1112912 CDS YP_005153882.1 376279876 11727648 188699..189556 1 NC_016797.1 identified by similarity to OMNI:CC0144; match to protein family HMM PF00590; match to protein family HMM TIGR00096; tetrapyrrole methylase family protein 189556 11727648 BSVBI22_A0177 Brucella suis VBI22 tetrapyrrole methylase family protein YP_005153882.1 188699 D 1112912 CDS YP_005153883.1 376279877 11727649 189553..189933 1 NC_016797.1 identified by similarity to GP:15073266; match to protein family HMM PF02021; hypothetical protein 189933 11727649 BSVBI22_A0178 Brucella suis VBI22 hypothetical protein YP_005153883.1 189553 D 1112912 CDS YP_005153884.1 376279878 11727650 190153..191586 1 NC_016797.1 identified by similarity to SP:P11098; match to protein family HMM PF00590; match to protein family HMM TIGR01469; match to protein family HMM TIGR01470; siroheme synthase 191586 cysG 11727650 cysG Brucella suis VBI22 siroheme synthase YP_005153884.1 190153 D 1112912 CDS YP_005153885.1 376279879 11727651 191604..191906 1 NC_016797.1 identified by similarity to GP:15156533; hypothetical protein 191906 11727651 BSVBI22_A0180 Brucella suis VBI22 hypothetical protein YP_005153885.1 191604 D 1112912 CDS YP_005153886.1 376279880 11727652 191927..193597 1 NC_016797.1 identified by similarity to OMNI:CC1119; match to protein family HMM PF01077; match to protein family HMM PF03460; sulfite reductase (NADPH) hemoprotein beta-component 193597 cysI 11727652 cysI Brucella suis VBI22 sulfite reductase (NADPH) hemoprotein beta-component YP_005153886.1 191927 D 1112912 CDS YP_005153887.1 376279881 11727653 193587..194345 1 NC_016797.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 194345 cysH 11727653 cysH Brucella suis VBI22 phosphoadenosine phosphosulfate reductase YP_005153887.1 193587 D 1112912 CDS YP_005153888.1 376279882 11727654 194398..194922 1 NC_016797.1 identified by similarity to GP:15156535; hypothetical protein 194922 11727654 BSVBI22_A0183 Brucella suis VBI22 hypothetical protein YP_005153888.1 194398 D 1112912 CDS YP_005153889.1 376279883 11727655 194990..195283 1 NC_016797.1 identified by similarity to GP:14021352; hypothetical protein 195283 11727655 BSVBI22_A0184 Brucella suis VBI22 hypothetical protein YP_005153889.1 194990 D 1112912 CDS YP_005153890.1 376279884 11727656 complement(195284..195862) 1 NC_016797.1 identified by similarity to OMNI:CC0659; match to protein family HMM PF01035; match to protein family HMM TIGR00589; methylated-DNA--protein-cysteine methyltransferase 195862 ogt 11727656 ogt Brucella suis VBI22 methylated-DNA--protein-cysteine methyltransferase YP_005153890.1 195284 R 1112912 CDS YP_005153891.1 376279885 11727657 196120..196365 1 NC_016797.1 identified by similarity to GP:14025509; hypothetical protein 196365 11727657 BSVBI22_A0186 Brucella suis VBI22 hypothetical protein YP_005153891.1 196120 D 1112912 CDS YP_005153892.1 376279886 11727658 complement(196418..196807) 1 NC_016797.1 identified by similarity to GP:15073804; hypothetical protein 196807 11727658 BSVBI22_A0187 Brucella suis VBI22 hypothetical protein YP_005153892.1 196418 R 1112912 CDS YP_005153893.1 376279887 11727659 197121..200906 1 NC_016797.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 200906 metH 11727659 metH Brucella suis VBI22 B12-dependent methionine synthase YP_005153893.1 197121 D 1112912 CDS YP_005153894.1 376279888 11727660 complement(200870..201037) 1 NC_016797.1 hypothetical protein 201037 11727660 BSVBI22_A0189 Brucella suis VBI22 hypothetical protein YP_005153894.1 200870 R 1112912 CDS YP_005153895.1 376279889 11727661 201227..201934 1 NC_016797.1 identified by match to protein family HMM PF00196; match to protein family HMM PF03472; LuxR family transcriptional regulator 201934 11727661 BSVBI22_A0190 Brucella suis VBI22 LuxR family transcriptional regulator YP_005153895.1 201227 D 1112912 CDS YP_005153896.1 376279890 11727662 202049..203419 1 NC_016797.1 identified by match to protein family HMM PF00202; aminotransferase 203419 11727662 BSVBI22_A0191 Brucella suis VBI22 aminotransferase YP_005153896.1 202049 D 1112912 CDS YP_005153897.1 376279891 11727663 complement(203459..203644) 1 NC_016797.1 hypothetical protein 203644 11727663 BSVBI22_A0192 Brucella suis VBI22 hypothetical protein YP_005153897.1 203459 R 1112912 CDS YP_005153898.1 376279892 11727664 203823..204725 1 NC_016797.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 204725 cysD 11727664 cysD Brucella suis VBI22 sulfate adenylyltransferase subunit 2 YP_005153898.1 203823 D 1112912 CDS YP_005153899.1 376279893 11727665 204725..206659 1 NC_016797.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase 206659 cysNC 11727665 cysNC Brucella suis VBI22 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase YP_005153899.1 204725 D 1112912 CDS YP_005153900.1 376279894 11727666 206707..207507 1 NC_016797.1 identified by similarity to SP:P22255; match to protein family HMM PF00459; match to protein family HMM TIGR01331; 3'(2'),5'-bisphosphate nucleotidase 207507 cysQ 11727666 cysQ Brucella suis VBI22 3'(2'),5'-bisphosphate nucleotidase YP_005153900.1 206707 D 1112912 CDS YP_005153901.1 376279895 11727668 complement(207769..208530) 1 NC_016797.1 identified by match to protein family HMM PF00027; Crp/FNR family transcriptional regulator 208530 11727668 BSVBI22_A0196 Brucella suis VBI22 Crp/FNR family transcriptional regulator YP_005153901.1 207769 R 1112912 CDS YP_005153902.1 376279896 11727670 209483..209614 1 NC_016797.1 hypothetical protein 209614 11727670 BSVBI22_A0198 Brucella suis VBI22 hypothetical protein YP_005153902.1 209483 D 1112912 CDS YP_005153903.1 376279897 11727671 209836..210627 1 NC_016797.1 identified by similarity to SP:P09392; match to protein family HMM PF00455; glycerol-3-phosphate transcriptional regulator 210627 glpR 11727671 glpR Brucella suis VBI22 glycerol-3-phosphate transcriptional regulator YP_005153903.1 209836 D 1112912 CDS YP_005153904.1 376279898 11727672 210709..212220 1 NC_016797.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 212220 glpD 11727672 glpD Brucella suis VBI22 glycerol-3-phosphate dehydrogenase YP_005153904.1 210709 D 1112912 CDS YP_005153905.1 376279899 11727674 213557..215074 1 NC_016797.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase family protein 215074 11727674 BSVBI22_A0202 Brucella suis VBI22 aldehyde dehydrogenase family protein YP_005153905.1 213557 D 1112912 CDS YP_005153906.1 376279900 11727675 215555..216589 1 NC_016797.1 identified by similarity to SP:P42327; match to protein family HMM PF00107; zinc-containing alcohol dehydrogenase 216589 11727675 BSVBI22_A0203 Brucella suis VBI22 zinc-containing alcohol dehydrogenase YP_005153906.1 215555 D 1112912 CDS YP_005153907.1 376279901 11727676 216680..217012 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5214; match to protein family HMM PF05610; hypothetical protein 217012 11727676 BSVBI22_A0204 Brucella suis VBI22 hypothetical protein YP_005153907.1 216680 D 1112912 CDS YP_005153908.1 376279902 11727679 219541..220110 1 NC_016797.1 hypothetical protein 220110 11727679 BSVBI22_A0207 Brucella suis VBI22 hypothetical protein YP_005153908.1 219541 D 1112912 CDS YP_005153909.1 376279903 11727680 complement(220152..220250) 1 NC_016797.1 hypothetical protein 220250 11727680 BSVBI22_A0208 Brucella suis VBI22 hypothetical protein YP_005153909.1 220152 R 1112912 CDS YP_005153910.1 376279904 11727681 220245..220400 1 NC_016797.1 hypothetical protein 220400 11727681 BSVBI22_A0209 Brucella suis VBI22 hypothetical protein YP_005153910.1 220245 D 1112912 CDS YP_005153911.1 376279905 11727682 220413..221846 1 NC_016797.1 identified by similarity to EGAD:17385; match to protein family HMM PF00171; aldehyde dehydrogenase family protein 221846 11727682 BSVBI22_A0210 Brucella suis VBI22 aldehyde dehydrogenase family protein YP_005153911.1 220413 D 1112912 CDS YP_005153912.1 376279906 11727683 complement(221891..222667) 1 NC_016797.1 identified by match to protein family HMM PF00528; ABC transporter permease 222667 11727683 BSVBI22_A0211 Brucella suis VBI22 ABC transporter permease YP_005153912.1 221891 R 1112912 CDS YP_005153913.1 376279907 11727684 complement(222664..223362) 1 NC_016797.1 identified by similarity to EGAD:24145; match to protein family HMM PF03070; transcriptional regulator TenA 223362 11727684 BSVBI22_A0212 Brucella suis VBI22 transcriptional regulator TenA YP_005153913.1 222664 R 1112912 CDS YP_005153914.1 376279908 11727685 complement(223359..224327) 1 NC_016797.1 ABC transporter periplasmic substrate-binding protein 224327 11727685 BSVBI22_A0213 Brucella suis VBI22 ABC transporter periplasmic substrate-binding protein YP_005153914.1 223359 R 1112912 CDS YP_005153915.1 376279909 11727686 complement(224351..224962) 1 NC_016797.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 224962 thiE 11727686 thiE Brucella suis VBI22 thiamine-phosphate pyrophosphorylase YP_005153915.1 224351 R 1112912 CDS YP_005153916.1 376279910 11727687 complement(224959..225729) 1 NC_016797.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 225729 thiG 11727687 thiG Brucella suis VBI22 thiazole synthase YP_005153916.1 224959 R 1112912 CDS YP_005153917.1 376279911 11727688 complement(225731..225928) 1 NC_016797.1 identified by similarity to SP:O32583; match to protein family HMM PF02597; match to protein family HMM TIGR01683; thiamine biosynthesis protein ThiS 225928 11727688 BSVBI22_A0216 Brucella suis VBI22 thiamine biosynthesis protein ThiS YP_005153917.1 225731 R 1112912 CDS YP_005153918.1 376279912 11727689 complement(225925..226929) 1 NC_016797.1 identified by match to protein family HMM PF01266; D-amino acid oxidase family protein 226929 11727689 BSVBI22_A0217 Brucella suis VBI22 D-amino acid oxidase family protein YP_005153918.1 225925 R 1112912 CDS YP_005153919.1 376279913 11727690 complement(226929..227804) 1 NC_016797.1 identified by match to protein family HMM TIGR00097; phosphomethylpyrimidine kinase 227804 thiD 11727690 thiD Brucella suis VBI22 phosphomethylpyrimidine kinase YP_005153919.1 226929 R 1112912 CDS YP_005153920.1 376279914 11727691 228233..230344 1 NC_016797.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; sensory box protein 230344 11727691 BSVBI22_A0219 Brucella suis VBI22 sensory box protein YP_005153920.1 228233 D 1112912 CDS YP_005153921.1 376279915 11727692 230443..232923 1 NC_016797.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR00003; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper-translocating P-type ATPase 232923 11727692 BSVBI22_A0220 Brucella suis VBI22 copper-translocating P-type ATPase YP_005153921.1 230443 D 1112912 CDS YP_005153922.1 376279916 11727693 complement(232903..233352) 1 NC_016797.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 233352 11727693 BSVBI22_A0221 Brucella suis VBI22 MerR family transcriptional regulator YP_005153922.1 232903 R 1112912 CDS YP_005153923.1 376279917 11727694 complement(233458..234204) 1 NC_016797.1 identified by match to protein family HMM PF00528; ABC transporter permease 234204 11727694 BSVBI22_A0222 Brucella suis VBI22 ABC transporter permease YP_005153923.1 233458 R 1112912 CDS YP_005153924.1 376279918 11727695 complement(234201..235139) 1 NC_016797.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 235139 11727695 BSVBI22_A0223 Brucella suis VBI22 ABC transporter ATP-binding protein YP_005153924.1 234201 R 1112912 CDS YP_005153925.1 376279919 11727696 complement(235136..236296) 1 NC_016797.1 identified by similarity to SP:P33361; match to protein family HMM PF00528; ABC transporter permease 236296 11727696 BSVBI22_A0224 Brucella suis VBI22 ABC transporter permease YP_005153925.1 235136 R 1112912 CDS YP_005153926.1 376279920 11727697 complement(236369..237283) 1 NC_016797.1 identified by similarity to GP:17983752; match to protein family HMM PF04069; ABC transporter periplasmic substrate-binding protein 237283 11727697 BSVBI22_A0225 Brucella suis VBI22 ABC transporter periplasmic substrate-binding protein YP_005153926.1 236369 R 1112912 CDS YP_005153927.1 376279921 11727698 complement(237469..238134) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0782; hypothetical protein 238134 11727698 BSVBI22_A0226 Brucella suis VBI22 hypothetical protein YP_005153927.1 237469 R 1112912 CDS YP_005153928.1 376279922 11727699 complement(238424..239689) 1 NC_016797.1 identified by similarity to EGAD:22862; match to protein family HMM PF00208; match to protein family HMM PF02812; glutamate dehydrogenase 239689 11727699 BSVBI22_A0227 Brucella suis VBI22 glutamate dehydrogenase YP_005153928.1 238424 R 1112912 CDS YP_005153929.1 376279923 11727700 239880..240047 1 NC_016797.1 hypothetical protein 240047 11727700 BSVBI22_A0228 Brucella suis VBI22 hypothetical protein YP_005153929.1 239880 D 1112912 CDS YP_005153930.1 376279924 11727701 240016..241269 1 NC_016797.1 identified by similarity to SP:P40875; match to protein family HMM PF01266; match to protein family HMM TIGR01373; sarcosine oxidase, beta subunit 241269 soxB 11727701 soxB Brucella suis VBI22 sarcosine oxidase, beta subunit YP_005153930.1 240016 D 1112912 CDS YP_005153931.1 376279925 11727702 241288..241593 1 NC_016797.1 identified by similarity to EGAD:43131; match to protein family HMM PF04267; match to protein family HMM TIGR01374; sarcosine oxidase subunit delta 241593 soxD 11727702 soxD Brucella suis VBI22 sarcosine oxidase subunit delta YP_005153931.1 241288 D 1112912 CDS YP_005153932.1 376279926 11727703 241593..244592 1 NC_016797.1 identified by similarity to EGAD:43132; match to protein family HMM PF01571; match to protein family HMM TIGR01372; sarcosine oxidase, alpha subunit 244592 soxA 11727703 soxA Brucella suis VBI22 sarcosine oxidase, alpha subunit YP_005153932.1 241593 D 1112912 CDS YP_005153933.1 376279927 11727704 244603..245157 1 NC_016797.1 identified by similarity to EGAD:43133; match to protein family HMM PF04268; sarcosine oxidase, gamma subunit 245157 soxG 11727704 soxG Brucella suis VBI22 sarcosine oxidase, gamma subunit YP_005153933.1 244603 D 1112912 CDS YP_005153934.1 376279928 11727705 complement(245210..246058) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5639; hypothetical protein 246058 11727705 BSVBI22_A0233 Brucella suis VBI22 hypothetical protein YP_005153934.1 245210 R 1112912 CDS YP_005153935.1 376279929 11727706 complement(246116..246910) 1 NC_016797.1 identified by match to protein family HMM PF01614; IclR family transcriptional regulator 246910 11727706 BSVBI22_A0234 Brucella suis VBI22 IclR family transcriptional regulator YP_005153935.1 246116 R 1112912 CDS YP_005153936.1 376279930 11727707 247068..248387 1 NC_016797.1 identified by match to protein family HMM PF01547; sugar ABC transporter periplasmic sugar-binding protein 248387 11727707 BSVBI22_A0235 Brucella suis VBI22 sugar ABC transporter periplasmic sugar-binding protein YP_005153936.1 247068 D 1112912 CDS YP_005153937.1 376279931 11727708 248448..249371 1 NC_016797.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 249371 11727708 BSVBI22_A0236 Brucella suis VBI22 sugar ABC transporter permease YP_005153937.1 248448 D 1112912 CDS YP_005153938.1 376279932 11727709 249374..250249 1 NC_016797.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 250249 11727709 BSVBI22_A0237 Brucella suis VBI22 sugar ABC transporter permease YP_005153938.1 249374 D 1112912 CDS YP_005153939.1 376279933 11727710 250257..251348 1 NC_016797.1 identified by similarity to SP:Q00752; match to protein family HMM PF00005; match to protein family HMM PF03459; sugar ABC transporter ATP-binding protein 251348 11727710 BSVBI22_A0238 Brucella suis VBI22 sugar ABC transporter ATP-binding protein YP_005153939.1 250257 D 1112912 CDS YP_005153940.1 376279934 11727711 251351..252469 1 NC_016797.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase/muconate lactonizing protein 252469 11727711 BSVBI22_A0239 Brucella suis VBI22 mandelate racemase/muconate lactonizing protein YP_005153940.1 251351 D 1112912 CDS YP_005153941.1 376279935 11727712 252466..252810 1 NC_016797.1 identified by similarity to GP:15140572; match to protein family HMM PF05336; hypothetical protein 252810 11727712 BSVBI22_A0240 Brucella suis VBI22 hypothetical protein YP_005153941.1 252466 D 1112912 CDS YP_005153942.1 376279936 11727713 252803..253882 1 NC_016797.1 identified by match to protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase 253882 11727713 BSVBI22_A0241 Brucella suis VBI22 Gfo/Idh/MocA family oxidoreductase YP_005153942.1 252803 D 1112912 CDS YP_005153943.1 376279937 11727714 253885..253983 1 NC_016797.1 hypothetical protein 253983 11727714 BSVBI22_A0242 Brucella suis VBI22 hypothetical protein YP_005153943.1 253885 D 1112912 CDS YP_005153944.1 376279938 11727715 253987..254721 1 NC_016797.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 254721 11727715 BSVBI22_A0243 Brucella suis VBI22 short chain dehydrogenase/reductase family oxidoreductase YP_005153944.1 253987 D 1112912 CDS YP_005153945.1 376279939 11727716 254762..255607 1 NC_016797.1 identified by similarity to GP:15140576; match to protein family HMM PF01557; fumarylacetoacetate hydrolase family protein 255607 11727716 BSVBI22_A0244 Brucella suis VBI22 fumarylacetoacetate hydrolase family protein YP_005153945.1 254762 D 1112912 CDS YP_005153946.1 376279940 11727717 255621..256898 1 NC_016797.1 identified by match to protein family HMM PF01188; mandelate racemase/muconate lactonizing protein 256898 11727717 BSVBI22_A0245 Brucella suis VBI22 mandelate racemase/muconate lactonizing protein YP_005153946.1 255621 D 1112912 CDS YP_005153947.1 376279941 11727718 complement(257297..257848) 1 NC_016797.1 hypothetical protein 257848 11727718 BSVBI22_A0246 Brucella suis VBI22 hypothetical protein YP_005153947.1 257297 R 1112912 CDS YP_005153948.1 376279942 11727719 258066..258467 1 NC_016797.1 hypothetical protein 258467 11727719 BSVBI22_A0247 Brucella suis VBI22 hypothetical protein YP_005153948.1 258066 D 1112912 CDS YP_005153949.1 376279943 11727721 complement(259121..259294) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5069; match to protein family HMM PF03884; zinc-binding protein 259294 11727721 BSVBI22_A0248 Brucella suis VBI22 zinc-binding protein YP_005153949.1 259121 R 1112912 CDS YP_005153950.1 376279944 11727722 complement(259346..259972) 1 NC_016797.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 259972 maf 11727722 maf Brucella suis VBI22 Maf-like protein YP_005153950.1 259346 R 1112912 CDS YP_005153951.1 376279945 11727723 complement(260006..260224) 1 NC_016797.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 260224 infA 11727723 infA Brucella suis VBI22 translation initiation factor IF-1 YP_005153951.1 260006 R 1112912 CDS YP_005153952.1 376279946 11727724 complement(260336..260809) 1 NC_016797.1 identified by match to protein family HMM PF01451; protein phosphatase 260809 11727724 BSVBI22_A0251 Brucella suis VBI22 protein phosphatase YP_005153952.1 260336 R 1112912 CDS YP_005153953.1 376279947 11727725 complement(260816..261298) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5073; hypothetical protein 261298 11727725 BSVBI22_A0252 Brucella suis VBI22 hypothetical protein YP_005153953.1 260816 R 1112912 CDS YP_005153954.1 376279948 11727726 complement(261305..262597) 1 NC_016797.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 262597 hisD 11727726 hisD Brucella suis VBI22 histidinol dehydrogenase YP_005153954.1 261305 R 1112912 CDS YP_005153955.1 376279949 11727727 complement(262672..263112) 1 NC_016797.1 identified by similarity to GP:15073540; hypothetical protein 263112 11727727 BSVBI22_A0254 Brucella suis VBI22 hypothetical protein YP_005153955.1 262672 R 1112912 CDS YP_005153956.1 376279950 11727728 complement(263383..264672) 1 NC_016797.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 264672 murA 11727728 murA Brucella suis VBI22 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_005153956.1 263383 R 1112912 CDS YP_005153957.1 376279951 11727729 complement(264895..265074) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5077; hypothetical protein 265074 11727729 BSVBI22_A0256 Brucella suis VBI22 hypothetical protein YP_005153957.1 264895 R 1112912 CDS YP_005153958.1 376279952 11727731 265389..267143 1 NC_016797.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; phage integrase family site specific recombinase 267143 11727731 BSVBI22_A0257 Brucella suis VBI22 phage integrase family site specific recombinase YP_005153958.1 265389 D 1112912 CDS YP_005153959.1 376279953 11727732 complement(267133..267246) 1 NC_016797.1 hypothetical protein 267246 11727732 BSVBI22_A0258 Brucella suis VBI22 hypothetical protein YP_005153959.1 267133 R 1112912 CDS YP_005153960.1 376279954 11727733 267238..267660 1 NC_016797.1 identified by match to protein family HMM PF02498; BRO family protein 267660 11727733 BSVBI22_A0259 Brucella suis VBI22 BRO family protein YP_005153960.1 267238 D 1112912 CDS YP_005153961.1 376279955 11727734 267673..267867 1 NC_016797.1 hypothetical protein 267867 11727734 BSVBI22_A0260 Brucella suis VBI22 hypothetical protein YP_005153961.1 267673 D 1112912 CDS YP_005153962.1 376279956 11727735 268459..269076 1 NC_016797.1 identified by match to protein family HMM PF00239; resolvase family site-specific recombinase 269076 11727735 BSVBI22_A0261 Brucella suis VBI22 resolvase family site-specific recombinase YP_005153962.1 268459 D 1112912 CDS YP_005153963.1 376279957 11727736 269634..270998 1 NC_016797.1 hypothetical protein 270998 11727736 BSVBI22_A0262 Brucella suis VBI22 hypothetical protein YP_005153963.1 269634 D 1112912 CDS YP_005153964.1 376279958 11727737 271586..271765 1 NC_016797.1 hypothetical protein 271765 11727737 BSVBI22_A0263 Brucella suis VBI22 hypothetical protein YP_005153964.1 271586 D 1112912 CDS YP_005153965.1 376279959 11727738 complement(272239..272523) 1 NC_016797.1 hypothetical protein 272523 11727738 BSVBI22_A0264 Brucella suis VBI22 hypothetical protein YP_005153965.1 272239 R 1112912 CDS YP_005153966.1 376279960 11727739 complement(272637..272897) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3521; hypothetical protein 272897 11727739 BSVBI22_A0265 Brucella suis VBI22 hypothetical protein YP_005153966.1 272637 R 1112912 CDS YP_005153967.1 376279961 11727740 272981..273370 1 NC_016797.1 hypothetical protein 273370 11727740 BSVBI22_A0266 Brucella suis VBI22 hypothetical protein YP_005153967.1 272981 D 1112912 CDS YP_005153968.1 376279962 11727741 complement(273823..273927) 1 NC_016797.1 hypothetical protein 273927 11727741 BSVBI22_A0267 Brucella suis VBI22 hypothetical protein YP_005153968.1 273823 R 1112912 CDS YP_005153969.1 376279963 11727742 273962..274804 1 NC_016797.1 identified by similarity to SP:P42888; match to protein family HMM PF01774; urease accessory protein UreD 274804 ureD-1 11727742 ureD-1 Brucella suis VBI22 urease accessory protein UreD YP_005153969.1 273962 D 1112912 CDS YP_005153970.1 376279964 11727743 274957..275259 1 NC_016797.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 275259 ureA 11727743 ureA Brucella suis VBI22 urease subunit gamma YP_005153970.1 274957 D 1112912 CDS YP_005153971.1 376279965 11727744 275426..275731 1 NC_016797.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 275731 ureB 11727744 ureB Brucella suis VBI22 urease subunit beta YP_005153971.1 275426 D 1112912 CDS YP_005153972.1 376279966 11727745 275750..277462 1 NC_016797.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 277462 ureC 11727745 ureC Brucella suis VBI22 urease subunit alpha YP_005153972.1 275750 D 1112912 CDS YP_005153973.1 376279967 11727746 277478..277966 1 NC_016797.1 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 277966 ureE 11727746 ureE Brucella suis VBI22 urease accessory protein UreE YP_005153973.1 277478 D 1112912 CDS YP_005153974.1 376279968 11727747 277938..278624 1 NC_016797.1 identified by similarity to SP:Q07402; match to protein family HMM PF01730; urease accessory protein UreF 278624 11727747 BSVBI22_A0273 Brucella suis VBI22 urease accessory protein UreF YP_005153974.1 277938 D 1112912 CDS YP_005153975.1 376279969 11727748 278621..279247 1 NC_016797.1 identified by similarity to EGAD:19477; match to protein family HMM PF01495; match to protein family HMM TIGR00101; urease accessory protein UreG 279247 ureG-1 11727748 ureG-1 Brucella suis VBI22 urease accessory protein UreG YP_005153975.1 278621 D 1112912 CDS YP_005153976.1 376279970 11727750 complement(279604..281229) 1 NC_016797.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 281229 11727750 BSVBI22_A0275 Brucella suis VBI22 sensor histidine kinase YP_005153976.1 279604 R 1112912 CDS YP_005153977.1 376279971 11727751 complement(281246..281551) 1 NC_016797.1 hypothetical protein 281551 11727751 BSVBI22_A0276 Brucella suis VBI22 hypothetical protein YP_005153977.1 281246 R 1112912 CDS YP_005153978.1 376279972 11727752 281514..282665 1 NC_016797.1 identified by similarity to GP:15075163; match to protein family HMM TIGR01730; transporter 282665 11727752 BSVBI22_A0277 Brucella suis VBI22 transporter YP_005153978.1 281514 D 1112912 CDS YP_005153979.1 376279973 11727753 282680..285811 1 NC_016797.1 identified by match to protein family HMM PF00873; AcrB/AcrD/AcrF multidrug efflux protein 285811 11727753 BSVBI22_A0278 Brucella suis VBI22 AcrB/AcrD/AcrF multidrug efflux protein YP_005153979.1 282680 D 1112912 CDS YP_005153980.1 376279974 11727754 complement(285934..287403) 1 NC_016797.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 287403 dhT 11727754 dhT Brucella suis VBI22 phenylhydantoinase YP_005153980.1 285934 R 1112912 CDS YP_005153981.1 376279975 11727755 complement(287455..288702) 1 NC_016797.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 288702 11727755 BSVBI22_A0280 Brucella suis VBI22 allantoate amidohydrolase YP_005153981.1 287455 R 1112912 CDS YP_005153982.1 376279976 11727756 288921..289604 1 NC_016797.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 289604 11727756 BSVBI22_A0281 Brucella suis VBI22 TetR family transcriptional regulator YP_005153982.1 288921 D 1112912 CDS YP_005153983.1 376279977 11727757 289601..289990 1 NC_016797.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 289990 11727757 BSVBI22_A0282 Brucella suis VBI22 MutT/nudix family protein YP_005153983.1 289601 D 1112912 CDS YP_005153984.1 376279978 11727758 complement(290035..291345) 1 NC_016797.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 291345 11727758 BSVBI22_A0283 Brucella suis VBI22 dihydropyrimidine dehydrogenase YP_005153984.1 290035 R 1112912 CDS YP_005153985.1 376279979 11727759 complement(291349..292854) 1 NC_016797.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 292854 11727759 BSVBI22_A0284 Brucella suis VBI22 putative oxidoreductase YP_005153985.1 291349 R 1112912 CDS YP_005153986.1 376279980 11727760 complement(293033..293485) 1 NC_016797.1 identified by similarity to GP:15073317; hypothetical protein 293485 11727760 BSVBI22_A0285 Brucella suis VBI22 hypothetical protein YP_005153986.1 293033 R 1112912 CDS YP_005153987.1 376279981 11727761 293636..295285 1 NC_016797.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 295285 pgi 11727761 pgi Brucella suis VBI22 glucose-6-phosphate isomerase YP_005153987.1 293636 D 1112912 CDS YP_005153988.1 376279982 11727762 295521..296582 1 NC_016797.1 identified by similarity to GP:15073237; hypothetical protein 296582 11727762 BSVBI22_A0287 Brucella suis VBI22 hypothetical protein YP_005153988.1 295521 D 1112912 CDS YP_005153989.1 376279983 11727763 296579..297328 1 NC_016797.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; HAD superfamily hydrolase 297328 11727763 BSVBI22_A0288 Brucella suis VBI22 HAD superfamily hydrolase YP_005153989.1 296579 D 1112912 CDS YP_005153990.1 376279984 11727764 complement(297301..298173) 1 NC_016797.1 identified by similarity to OMNI:NTL03PA01240; hypothetical protein 298173 11727764 BSVBI22_A0289 Brucella suis VBI22 hypothetical protein YP_005153990.1 297301 R 1112912 CDS YP_005153991.1 376279985 11727765 complement(298199..299863) 1 NC_016797.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 299863 fadD 11727765 fadD Brucella suis VBI22 acyl-CoA synthetase YP_005153991.1 298199 R 1112912 CDS YP_005153992.1 376279986 11727766 complement(300295..300924) 1 NC_016797.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 300924 11727766 BSVBI22_A0291 Brucella suis VBI22 TetR family transcriptional regulator YP_005153992.1 300295 R 1112912 CDS YP_005153993.1 376279987 11727767 301097..302290 1 NC_016797.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; HlyD family secretion protein 302290 11727767 BSVBI22_A0292 Brucella suis VBI22 HlyD family secretion protein YP_005153993.1 301097 D 1112912 CDS YP_005153994.1 376279988 11727768 302287..305442 1 NC_016797.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; hydrophobe/amphiphile efflux-1 family protein 305442 11727768 BSVBI22_A0293 Brucella suis VBI22 hydrophobe/amphiphile efflux-1 family protein YP_005153994.1 302287 D 1112912 CDS YP_005153995.1 376279989 11727769 complement(305553..305720) 1 NC_016797.1 hypothetical protein 305720 11727769 BSVBI22_A0294 Brucella suis VBI22 hypothetical protein YP_005153995.1 305553 R 1112912 CDS YP_005153996.1 376279990 11727770 complement(305941..306081) 1 NC_016797.1 hypothetical protein 306081 11727770 BSVBI22_A0295 Brucella suis VBI22 hypothetical protein YP_005153996.1 305941 R 1112912 CDS YP_005153997.1 376279991 11727771 complement(306150..306992) 1 NC_016797.1 identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 306992 11727771 BSVBI22_A0296 Brucella suis VBI22 amino acid ABC transporter substrate-binding protein YP_005153997.1 306150 R 1112912 CDS YP_005153998.1 376279992 11727772 307258..309150 1 NC_016797.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 309150 11727772 BSVBI22_A0297 Brucella suis VBI22 glycosyl transferase family protein YP_005153998.1 307258 D 1112912 CDS YP_005153999.1 376279993 11727773 complement(309078..310037) 1 NC_016797.1 identified by similarity to GP:15155336; match to protein family HMM PF03976; hypothetical protein 310037 11727773 BSVBI22_A0298 Brucella suis VBI22 hypothetical protein YP_005153999.1 309078 R 1112912 CDS YP_005154000.1 376279994 11727774 310170..311486 1 NC_016797.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 311486 11727774 BSVBI22_A0299 Brucella suis VBI22 sensor histidine kinase YP_005154000.1 310170 D 1112912 CDS YP_005154001.1 376279995 11727775 complement(311616..312158) 1 NC_016797.1 identified by similarity to GP:15073446; hypothetical protein 312158 11727775 BSVBI22_A0300 Brucella suis VBI22 hypothetical protein YP_005154001.1 311616 R 1112912 CDS YP_005154002.1 376279996 11727776 complement(312330..312671) 1 NC_016797.1 hypothetical protein 312671 11727776 BSVBI22_A0301 Brucella suis VBI22 hypothetical protein YP_005154002.1 312330 R 1112912 CDS YP_005154003.1 376279997 11727777 312761..313972 1 NC_016797.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine transaminase protein 313972 argD 11727777 argD Brucella suis VBI22 acetylornithine transaminase protein YP_005154003.1 312761 D 1112912 CDS YP_005154004.1 376279998 11727778 313977..314915 1 NC_016797.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 314915 argF 11727778 argF Brucella suis VBI22 ornithine carbamoyltransferase YP_005154004.1 313977 D 1112912 CDS YP_005154005.1 376279999 11727779 314917..315939 1 NC_016797.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 315939 hslO 11727779 hslO Brucella suis VBI22 Hsp33-like chaperonin YP_005154005.1 314917 D 1112912 CDS YP_005154006.1 376280000 11727780 complement(315980..316372) 1 NC_016797.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 316372 apaG 11727780 apaG Brucella suis VBI22 ApaG protein YP_005154006.1 315980 R 1112912 CDS YP_005154007.1 376280001 11727781 complement(316741..317937) 1 NC_016797.1 catalyzes the conversion of O-succinylhomoserine and sulfide to homocysteine; second step in methionine biosynthesis; O-succinylhomoserine sulfhydrylase 317937 metZ 11727781 metZ Brucella suis VBI22 O-succinylhomoserine sulfhydrylase YP_005154007.1 316741 R 1112912 CDS YP_005154008.1 376280002 11727782 318364..319455 1 NC_016797.1 Catalyzes the deamination of dCTP to form dUTP; 2'-deoxycytidine 5'-triphosphate deaminase 319455 11727782 BSVBI22_A0307 Brucella suis VBI22 2'-deoxycytidine 5'-triphosphate deaminase YP_005154008.1 318364 D 1112912 CDS YP_005154009.1 376280003 11727783 319546..320562 1 NC_016797.1 identified by match to protein family HMM PF00165; match to protein family HMM PF01965; AraC family transcriptional regulator 320562 11727783 BSVBI22_A0308 Brucella suis VBI22 AraC family transcriptional regulator YP_005154009.1 319546 D 1112912 CDS YP_005154010.1 376280004 11727784 320649..320915 1 NC_016797.1 identified by similarity to GP:15155415; hypothetical protein 320915 11727784 BSVBI22_A0309 Brucella suis VBI22 hypothetical protein YP_005154010.1 320649 D 1112912 CDS YP_005154011.1 376280005 11727785 321015..321434 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6482; match to protein family HMM PF00188; hypothetical protein 321434 11727785 BSVBI22_A0310 Brucella suis VBI22 hypothetical protein YP_005154011.1 321015 D 1112912 CDS YP_005154012.1 376280006 11727786 321609..322976 1 NC_016797.1 identified by similarity to EGAD:8949; match to protein family HMM PF01554; match to protein family HMM TIGR00797; DNA-damage-inducible protein F 322976 11727786 BSVBI22_A0311 Brucella suis VBI22 DNA-damage-inducible protein F YP_005154012.1 321609 D 1112912 CDS YP_005154013.1 376280007 11727787 complement(322978..324072) 1 NC_016797.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 324072 pyrD 11727787 pyrD Brucella suis VBI22 dihydroorotate dehydrogenase 2 YP_005154013.1 322978 R 1112912 CDS YP_005154014.1 376280008 11727788 complement(324069..324422) 1 NC_016797.1 identified by similarity to GP:15073480; hypothetical protein 324422 11727788 BSVBI22_A0313 Brucella suis VBI22 hypothetical protein YP_005154014.1 324069 R 1112912 CDS YP_005154015.1 376280009 11727789 324676..325131 1 NC_016797.1 identified by similarity to OMNI:NTL02ML4408; hypothetical protein 325131 11727789 BSVBI22_A0314 Brucella suis VBI22 hypothetical protein YP_005154015.1 324676 D 1112912 CDS YP_005154016.1 376280010 11727790 complement(325222..326172) 1 NC_016797.1 identified by similarity to EGAD:139406; match to protein family HMM PF00561; match to protein family HMM TIGR01249; proline iminopeptidase 326172 pip 11727790 pip Brucella suis VBI22 proline iminopeptidase YP_005154016.1 325222 R 1112912 CDS YP_005154017.1 376280011 11727791 326402..327043 1 NC_016797.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family DNA-binding response regulator 327043 11727791 BSVBI22_A0316 Brucella suis VBI22 LuxR family DNA-binding response regulator YP_005154017.1 326402 D 1112912 CDS YP_005154018.1 376280012 11727792 complement(327080..330604) 1 NC_016797.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase/response regulator 330604 11727792 BSVBI22_A0317 Brucella suis VBI22 sensor histidine kinase/response regulator YP_005154018.1 327080 R 1112912 CDS YP_005154019.1 376280013 11727793 complement(330889..331035) 1 NC_016797.1 hypothetical protein 331035 11727793 BSVBI22_A0318 Brucella suis VBI22 hypothetical protein YP_005154019.1 330889 R 1112912 CDS YP_005154020.1 376280014 11727794 331117..331533 1 NC_016797.1 homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 331533 mscL 11727794 mscL Brucella suis VBI22 large-conductance mechanosensitive channel YP_005154020.1 331117 D 1112912 CDS YP_005154021.1 376280015 11727795 complement(331609..332886) 1 NC_016797.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 332886 hemA 11727795 hemA Brucella suis VBI22 5-aminolevulinate synthase YP_005154021.1 331609 R 1112912 CDS YP_005154022.1 376280016 11727796 complement(333032..333733) 1 NC_016797.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 333733 11727796 BSVBI22_A0321 Brucella suis VBI22 polysaccharide deacetylase family protein YP_005154022.1 333032 R 1112912 CDS YP_005154023.1 376280017 11727797 complement(333742..334461) 1 NC_016797.1 identified by similarity to GP:12837556; match to protein family HMM PF01755; glycosyl transferase family protein 334461 11727797 BSVBI22_A0322 Brucella suis VBI22 glycosyl transferase family protein YP_005154023.1 333742 R 1112912 CDS YP_005154024.1 376280018 11727798 complement(334591..335265) 1 NC_016797.1 identified by similarity to GP:15157577; hypothetical protein 335265 11727798 BSVBI22_A0323 Brucella suis VBI22 hypothetical protein YP_005154024.1 334591 R 1112912 CDS YP_005154025.1 376280019 11727799 complement(335357..335590) 1 NC_016797.1 hypothetical protein 335590 11727799 BSVBI22_A0324 Brucella suis VBI22 hypothetical protein YP_005154025.1 335357 R 1112912 CDS YP_005154026.1 376280020 11727800 complement(335633..336523) 1 NC_016797.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 336523 11727800 BSVBI22_A0325 Brucella suis VBI22 LysR family transcriptional regulator YP_005154026.1 335633 R 1112912 CDS YP_005154027.1 376280021 11727801 336645..337064 1 NC_016797.1 identified by similarity to OMNI:NTL03PA03432; match to protein family HMM PF03788; hypothetical protein 337064 11727801 BSVBI22_A0326 Brucella suis VBI22 hypothetical protein YP_005154027.1 336645 D 1112912 CDS YP_005154028.1 376280022 11727802 337051..337758 1 NC_016797.1 identified by similarity to OMNI:NTL03PA03431; match to protein family HMM PF04172; hypothetical protein 337758 11727802 BSVBI22_A0327 Brucella suis VBI22 hypothetical protein YP_005154028.1 337051 D 1112912 CDS YP_005154029.1 376280023 11727803 337881..338267 1 NC_016797.1 hypothetical protein 338267 11727803 BSVBI22_A0328 Brucella suis VBI22 hypothetical protein YP_005154029.1 337881 D 1112912 CDS YP_005154030.1 376280024 11727804 338305..339546 1 NC_016797.1 identified by similarity to GP:15155313; putative lipoprotein 339546 11727804 BSVBI22_A0329 Brucella suis VBI22 putative lipoprotein YP_005154030.1 338305 D 1112912 CDS YP_005154031.1 376280025 11727805 339633..340514 1 NC_016797.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 340514 panC 11727805 panC Brucella suis VBI22 pantoate--beta-alanine ligase YP_005154031.1 339633 D 1112912 CDS YP_005154032.1 376280026 11727806 340516..341343 1 NC_016797.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 341343 panB 11727806 panB Brucella suis VBI22 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_005154032.1 340516 D 1112912 CDS YP_005154033.1 376280027 11727807 complement(341540..342316) 1 NC_016797.1 identified by similarity to SP:Q44532; match to protein family HMM PF00175; match to protein family HMM PF00970; ferredoxin--NADP reductase 342316 fpr 11727807 fpr Brucella suis VBI22 ferredoxin--NADP reductase YP_005154033.1 341540 R 1112912 CDS YP_005154034.1 376280028 11727808 342438..342530 1 NC_016797.1 hypothetical protein 342530 11727808 BSVBI22_A0333 Brucella suis VBI22 hypothetical protein YP_005154034.1 342438 D 1112912 CDS YP_005154035.1 376280029 11727809 342719..343069 1 NC_016797.1 hypothetical protein 343069 11727809 BSVBI22_A0334 Brucella suis VBI22 hypothetical protein YP_005154035.1 342719 D 1112912 CDS YP_005154036.1 376280030 11727810 343108..344205 1 NC_016797.1 identified by similarity to EGAD:19651; match to protein family HMM PF00278; match to protein family HMM TIGR01047; carboxynorspermidine decarboxylase 344205 nspC 11727810 nspC Brucella suis VBI22 carboxynorspermidine decarboxylase YP_005154036.1 343108 D 1112912 CDS YP_005154037.1 376280031 11727811 344386..345627 1 NC_016797.1 identified by similarity to GP:15141437; match to protein family HMM PF03435; hypothetical protein 345627 11727811 BSVBI22_A0336 Brucella suis VBI22 hypothetical protein YP_005154037.1 344386 D 1112912 CDS YP_005154038.1 376280032 11727812 complement(345643..345858) 1 NC_016797.1 hypothetical protein 345858 11727812 BSVBI22_A0337 Brucella suis VBI22 hypothetical protein YP_005154038.1 345643 R 1112912 CDS YP_005154039.1 376280033 11727813 complement(345883..346911) 1 NC_016797.1 identified by similarity to GP:9695312; match to protein family HMM PF05544; proline racemase 346911 11727813 BSVBI22_A0338 Brucella suis VBI22 proline racemase YP_005154039.1 345883 R 1112912 CDS YP_005154040.1 376280034 11727814 complement(346966..347073) 1 NC_016797.1 hypothetical protein 347073 11727814 BSVBI22_A0339 Brucella suis VBI22 hypothetical protein YP_005154040.1 346966 R 1112912 CDS YP_005154041.1 376280035 11727815 347364..348779 1 NC_016797.1 identified by similarity to SP:O82855; match to protein family HMM PF01554; match to protein family HMM TIGR00797; multidrug resistance protein NorM, putative 348779 11727815 BSVBI22_A0340 Brucella suis VBI22 multidrug resistance protein NorM, putative YP_005154041.1 347364 D 1112912 CDS YP_005154042.1 376280036 11727818 350973..351614 1 NC_016797.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family DNA-binding response regulator 351614 11727818 BSVBI22_A0343 Brucella suis VBI22 LuxR family DNA-binding response regulator YP_005154042.1 350973 D 1112912 CDS YP_005154043.1 376280037 11727819 351902..352450 1 NC_016797.1 identified by similarity to GP:15162042; match to protein family HMM PF04290; hypothetical protein 352450 11727819 BSVBI22_A0344 Brucella suis VBI22 hypothetical protein YP_005154043.1 351902 D 1112912 CDS YP_005154044.1 376280038 11727820 352462..354030 1 NC_016797.1 identified by match to protein family HMM TIGR00786; TRAP dicarboxylate transporter subunit DctM 354030 11727820 BSVBI22_A0345 Brucella suis VBI22 TRAP dicarboxylate transporter subunit DctM YP_005154044.1 352462 D 1112912 CDS YP_005154045.1 376280039 11727821 354092..355210 1 NC_016797.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR01409; extracellular solute-binding protein 355210 11727821 BSVBI22_A0346 Brucella suis VBI22 extracellular solute-binding protein YP_005154045.1 354092 D 1112912 CDS YP_005154046.1 376280040 11727822 complement(355293..356111) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3955; hypothetical protein 356111 11727822 BSVBI22_A0347 Brucella suis VBI22 hypothetical protein YP_005154046.1 355293 R 1112912 CDS YP_005154047.1 376280041 11727823 complement(356124..357551) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3956; match to protein family HMM PF01522; hypothetical protein 357551 11727823 BSVBI22_A0348 Brucella suis VBI22 hypothetical protein YP_005154047.1 356124 R 1112912 CDS YP_005154048.1 376280042 11727824 357819..358094 1 NC_016797.1 identified by similarity to GP:15140674; hypothetical protein 358094 11727824 BSVBI22_A0349 Brucella suis VBI22 hypothetical protein YP_005154048.1 357819 D 1112912 CDS YP_005154049.1 376280043 11727825 358100..359578 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3958; match to protein family HMM PF00111; match to protein family HMM PF00941; match to protein family HMM PF01799; match to protein family HMM PF03450; xanthine dehydrogenase 359578 11727825 BSVBI22_A0350 Brucella suis VBI22 xanthine dehydrogenase YP_005154049.1 358100 D 1112912 CDS YP_005154050.1 376280044 11727826 359591..361933 1 NC_016797.1 identified by match to protein family HMM PF01315; match to protein family HMM PF02738; xanthine dehydrogenase 361933 11727826 BSVBI22_A0351 Brucella suis VBI22 xanthine dehydrogenase YP_005154050.1 359591 D 1112912 CDS YP_005154051.1 376280045 11727827 362064..362810 1 NC_016797.1 identified by similarity to OMNI:CC2617; chaperone XdhC 362810 11727827 BSVBI22_A0352 Brucella suis VBI22 chaperone XdhC YP_005154051.1 362064 D 1112912 CDS YP_005154052.1 376280046 11727828 complement(362891..363805) 1 NC_016797.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 363805 11727828 BSVBI22_A0353 Brucella suis VBI22 LysR family transcriptional regulator YP_005154052.1 362891 R 1112912 CDS YP_005154053.1 376280047 11727829 363986..365230 1 NC_016797.1 identified by similarity to GP:15140681; hypothetical protein 365230 11727829 BSVBI22_A0354 Brucella suis VBI22 hypothetical protein YP_005154053.1 363986 D 1112912 CDS YP_005154054.1 376280048 11727830 365227..366531 1 NC_016797.1 Catalyzes the deamination of guanine; guanine deaminase 366531 11727830 BSVBI22_A0355 Brucella suis VBI22 guanine deaminase YP_005154054.1 365227 D 1112912 CDS YP_005154055.1 376280049 11727831 366611..367897 1 NC_016797.1 identified by similarity to EGAD:40602; match to protein family HMM PF05161; hydroxypyruvate reductase 367897 11727831 BSVBI22_A0356 Brucella suis VBI22 hydroxypyruvate reductase YP_005154055.1 366611 D 1112912 CDS YP_005154056.1 376280050 11727832 complement(367878..368036) 1 NC_016797.1 identified by match to protein family HMM PF03597; match to protein family HMM TIGR00847; cbb3-type cytochrome oxidase maturation protein 368036 ccoS 11727832 ccoS Brucella suis VBI22 cbb3-type cytochrome oxidase maturation protein YP_005154056.1 367878 R 1112912 CDS YP_005154057.1 376280051 11727833 complement(368033..370291) 1 NC_016797.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; nitrogen fixation protein FixI 370291 11727833 BSVBI22_A0358 Brucella suis VBI22 nitrogen fixation protein FixI YP_005154057.1 368033 R 1112912 CDS YP_005154058.1 376280052 11727834 complement(370288..370785) 1 NC_016797.1 identified by similarity to EGAD:10086; match to protein family HMM PF05751; FixH protein 370785 11727834 BSVBI22_A0359 Brucella suis VBI22 FixH protein YP_005154058.1 370288 R 1112912 CDS YP_005154059.1 376280053 11727835 complement(370785..372335) 1 NC_016797.1 iron-sulfur cluster-binding protein 372335 11727835 BSVBI22_A0360 Brucella suis VBI22 iron-sulfur cluster-binding protein YP_005154059.1 370785 R 1112912 CDS YP_005154060.1 376280054 11727836 complement(372495..373358) 1 NC_016797.1 identified by match to protein family HMM PF00034; match to protein family HMM TIGR00782; cytochrome c oxidase, cbb3-type subunit III 373358 ccoP 11727836 ccoP Brucella suis VBI22 cytochrome c oxidase, cbb3-type subunit III YP_005154060.1 372495 R 1112912 CDS YP_005154061.1 376280055 11727837 complement(373351..373509) 1 NC_016797.1 identified by similarity to EGAD:125983; match to protein family HMM PF05545; cytochrome c oxidase, cbb3-type, CcoQ subunit 373509 ccoQ 11727837 ccoQ Brucella suis VBI22 cytochrome c oxidase, cbb3-type, CcoQ subunit YP_005154061.1 373351 R 1112912 CDS YP_005154062.1 376280056 11727838 complement(373524..374255) 1 NC_016797.1 identified by match to protein family HMM PF02433; match to protein family HMM TIGR00781; cytochrome c oxidase, cbb3-type subunit II 374255 ccoO 11727838 ccoO Brucella suis VBI22 cytochrome c oxidase, cbb3-type subunit II YP_005154062.1 373524 R 1112912 CDS YP_005154063.1 376280057 11727839 complement(374270..375895) 1 NC_016797.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR00780; cytochrome c oxidase, cbb3-type subunit I 375895 ccoN 11727839 ccoN Brucella suis VBI22 cytochrome c oxidase, cbb3-type subunit I YP_005154063.1 374270 R 1112912 CDS YP_005154064.1 376280058 11727840 complement(376113..376571) 1 NC_016797.1 identified by match to protein family HMM PF01475; FUR family transcriptional regulator 376571 11727840 BSVBI22_A0365 Brucella suis VBI22 FUR family transcriptional regulator YP_005154064.1 376113 R 1112912 CDS YP_005154065.1 376280059 11727841 376570..376896 1 NC_016797.1 hypothetical protein 376896 11727841 BSVBI22_A0366 Brucella suis VBI22 hypothetical protein YP_005154065.1 376570 D 1112912 CDS YP_005154066.1 376280060 11727842 377013..377627 1 NC_016797.1 identified by similarity to GP:13235366; match to protein family HMM PF01323; match to protein family HMM TIGR01409; twin-arginine translocation pathway signal sequence domain-containing protein 377627 11727842 BSVBI22_A0367 Brucella suis VBI22 twin-arginine translocation pathway signal sequence domain-containing protein YP_005154066.1 377013 D 1112912 CDS YP_005154067.1 376280061 11727843 complement(377676..379121) 1 NC_016797.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase family protein 379121 11727843 BSVBI22_A0368 Brucella suis VBI22 aldehyde dehydrogenase family protein YP_005154067.1 377676 R 1112912 CDS YP_005154068.1 376280062 11727844 379320..380405 1 NC_016797.1 identified by similarity to EGAD:7337; match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM TIGR00589; ada regulatory protein 380405 ada 11727844 ada Brucella suis VBI22 ada regulatory protein YP_005154068.1 379320 D 1112912 CDS YP_005154069.1 376280063 11727845 380587..380937 1 NC_016797.1 identified by similarity to GP:15073235; match to protein family HMM PF03960; match to protein family HMM TIGR01617; hypothetical protein 380937 11727845 BSVBI22_A0370 Brucella suis VBI22 hypothetical protein YP_005154069.1 380587 D 1112912 CDS YP_005154070.1 376280064 11727846 381274..382317 1 NC_016797.1 identified by similarity to GP:15156192; hypothetical protein 382317 11727846 BSVBI22_A0371 Brucella suis VBI22 hypothetical protein YP_005154070.1 381274 D 1112912 CDS YP_005154071.1 376280065 11727848 383768..385015 1 NC_016797.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 385015 bacA 11727848 bacA Brucella suis VBI22 transporter YP_005154071.1 383768 D 1112912 CDS YP_005154072.1 376280066 11727849 complement(385054..386052) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5836; hypothetical protein 386052 11727849 BSVBI22_A0374 Brucella suis VBI22 hypothetical protein YP_005154072.1 385054 R 1112912 CDS YP_005154073.1 376280067 11727850 386298..386969 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5837; hypothetical protein 386969 11727850 BSVBI22_A0375 Brucella suis VBI22 hypothetical protein YP_005154073.1 386298 D 1112912 CDS YP_005154074.1 376280068 11727851 386991..388442 1 NC_016797.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 388442 engA 11727851 engA Brucella suis VBI22 GTP-binding protein EngA YP_005154074.1 386991 D 1112912 CDS YP_005154075.1 376280069 11727852 388601..389917 1 NC_016797.1 identified by similarity to SP:P04475; HSP70 family protein 389917 11727852 BSVBI22_A0377 Brucella suis VBI22 HSP70 family protein YP_005154075.1 388601 D 1112912 CDS YP_005154076.1 376280070 11727853 complement(390007..390132) 1 NC_016797.1 hypothetical protein 390132 11727853 BSVBI22_A0378 Brucella suis VBI22 hypothetical protein YP_005154076.1 390007 R 1112912 CDS YP_005154077.1 376280071 11727854 390354..391643 1 NC_016797.1 identified by similarity to GP:14026921; hypothetical protein 391643 11727854 BSVBI22_A0379 Brucella suis VBI22 hypothetical protein YP_005154077.1 390354 D 1112912 CDS YP_005154078.1 376280072 11727855 391671..391775 1 NC_016797.1 hypothetical protein 391775 11727855 BSVBI22_A0380 Brucella suis VBI22 hypothetical protein YP_005154078.1 391671 D 1112912 CDS YP_005154079.1 376280073 11727856 391805..391930 1 NC_016797.1 hypothetical protein 391930 11727856 BSVBI22_A0381 Brucella suis VBI22 hypothetical protein YP_005154079.1 391805 D 1112912 CDS YP_005154080.1 376280074 11727857 391914..392312 1 NC_016797.1 identified by similarity to EGAD:21946; ATP synthase protein I 392312 11727857 BSVBI22_A0382 Brucella suis VBI22 ATP synthase protein I YP_005154080.1 391914 D 1112912 CDS YP_005154081.1 376280075 11727858 392420..393169 1 NC_016797.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 393169 atpB 11727858 atpB Brucella suis VBI22 F0F1 ATP synthase subunit A YP_005154081.1 392420 D 1112912 CDS YP_005154082.1 376280076 11727859 393237..393464 1 NC_016797.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 393464 atpE 11727859 atpE Brucella suis VBI22 F0F1 ATP synthase subunit C YP_005154082.1 393237 D 1112912 CDS YP_005154083.1 376280077 11727860 393636..394262 1 NC_016797.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' 394262 11727860 BSVBI22_A0385 Brucella suis VBI22 F0F1 ATP synthase subunit B' YP_005154083.1 393636 D 1112912 CDS YP_005154084.1 376280078 11727861 394273..394752 1 NC_016797.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 394752 atpF 11727861 atpF Brucella suis VBI22 F0F1 ATP synthase subunit B YP_005154084.1 394273 D 1112912 CDS YP_005154085.1 376280079 11727862 complement(394875..395537) 1 NC_016797.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 395537 rnhB 11727862 rnhB Brucella suis VBI22 ribonuclease HII YP_005154085.1 394875 R 1112912 CDS YP_005154086.1 376280080 11727863 complement(395714..396886) 1 NC_016797.1 identified by similarity to GP:15073771; match to protein family HMM PF04055; hypothetical protein 396886 11727863 BSVBI22_A0388 Brucella suis VBI22 hypothetical protein YP_005154086.1 395714 R 1112912 CDS YP_005154087.1 376280081 11727864 397022..397528 1 NC_016797.1 identified by similarity to GP:15155690; hypothetical protein 397528 11727864 BSVBI22_A0389 Brucella suis VBI22 hypothetical protein YP_005154087.1 397022 D 1112912 CDS YP_005154088.1 376280082 11727865 complement(397608..397880) 1 NC_016797.1 hypothetical protein 397880 11727865 BSVBI22_A0390 Brucella suis VBI22 hypothetical protein YP_005154088.1 397608 R 1112912 CDS YP_005154089.1 376280083 11727866 397870..397977 1 NC_016797.1 hypothetical protein 397977 11727866 BSVBI22_A0391 Brucella suis VBI22 hypothetical protein YP_005154089.1 397870 D 1112912 CDS YP_005154090.1 376280084 11727867 complement(398024..398299) 1 NC_016797.1 hypothetical protein 398299 11727867 BSVBI22_A0392 Brucella suis VBI22 hypothetical protein YP_005154090.1 398024 R 1112912 CDS YP_005154091.1 376280085 11727868 complement(398371..398604) 1 NC_016797.1 hypothetical protein 398604 11727868 BSVBI22_A0393 Brucella suis VBI22 hypothetical protein YP_005154091.1 398371 R 1112912 CDS YP_005154092.1 376280086 11727869 complement(398567..398713) 1 NC_016797.1 hypothetical protein 398713 11727869 BSVBI22_A0394 Brucella suis VBI22 hypothetical protein YP_005154092.1 398567 R 1112912 CDS YP_005154093.1 376280087 11727870 complement(398658..399557) 1 NC_016797.1 identified by match to protein family HMM PF00288; match to protein family HMM TIGR00154; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 399557 ispE 11727870 ispE Brucella suis VBI22 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_005154093.1 398658 R 1112912 CDS YP_005154094.1 376280088 11727871 complement(399587..399808) 1 NC_016797.1 hypothetical protein 399808 11727871 BSVBI22_A0396 Brucella suis VBI22 hypothetical protein YP_005154094.1 399587 R 1112912 CDS YP_005154095.1 376280089 11727872 complement(400239..401345) 1 NC_016797.1 identified by match to protein family HMM PF01343; protease IV 401345 11727872 BSVBI22_A0397 Brucella suis VBI22 protease IV YP_005154095.1 400239 R 1112912 CDS YP_005154096.1 376280090 11727873 complement(401266..402447) 1 NC_016797.1 identified by similarity to SP:P13738; match to protein family HMM TIGR00773; Na+/H+ antiporter 402447 nhaA 11727873 nhaA Brucella suis VBI22 Na+/H+ antiporter YP_005154096.1 401266 R 1112912 CDS YP_005154097.1 376280091 11727874 complement(402467..402688) 1 NC_016797.1 hypothetical protein 402688 11727874 BSVBI22_A0399 Brucella suis VBI22 hypothetical protein YP_005154097.1 402467 R 1112912 CDS YP_005154098.1 376280092 11727875 complement(402737..403495) 1 NC_016797.1 identified by similarity to GP:15073779; hypothetical protein 403495 11727875 BSVBI22_A0400 Brucella suis VBI22 hypothetical protein YP_005154098.1 402737 R 1112912 CDS YP_005154099.1 376280093 11727876 complement(403516..403743) 1 NC_016797.1 identified by similarity to GP:15073778; hypothetical protein 403743 11727876 BSVBI22_A0401 Brucella suis VBI22 hypothetical protein YP_005154099.1 403516 R 1112912 CDS YP_005154100.1 376280094 11727877 404006..405028 1 NC_016797.1 identified by match to protein family HMM PF00348; polyprenyl synthetase family protein 405028 11727877 BSVBI22_A0402 Brucella suis VBI22 polyprenyl synthetase family protein YP_005154100.1 404006 D 1112912 CDS YP_005154101.1 376280095 11727878 405332..407197 1 NC_016797.1 identified by match to protein family HMM PF00515; hypothetical protein 407197 11727878 BSVBI22_A0403 Brucella suis VBI22 hypothetical protein YP_005154101.1 405332 D 1112912 CDS YP_005154102.1 376280096 11727879 407349..408275 1 NC_016797.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 408275 glyQ 11727879 glyQ Brucella suis VBI22 glycyl-tRNA synthetase subunit alpha YP_005154102.1 407349 D 1112912 CDS YP_005154103.1 376280097 11727880 408394..410727 1 NC_016797.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 410727 glyS 11727880 glyS Brucella suis VBI22 glycyl-tRNA synthetase subunit beta YP_005154103.1 408394 D 1112912 CDS YP_005154104.1 376280098 11727881 410866..411837 1 NC_016797.1 identified by match to protein family HMM PF01300; match to protein family HMM PF03481; match to protein family HMM TIGR00057; Sua5/YciO/YrdC family protein 411837 11727881 BSVBI22_A0406 Brucella suis VBI22 Sua5/YciO/YrdC family protein YP_005154104.1 410866 D 1112912 CDS YP_005154105.1 376280099 11727882 411863..413275 1 NC_016797.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; oxidoreductase, FAD-binding protein 413275 11727882 BSVBI22_A0407 Brucella suis VBI22 oxidoreductase, FAD-binding protein YP_005154105.1 411863 D 1112912 CDS YP_005154106.1 376280100 11727883 complement(413313..413630) 1 NC_016797.1 identified by similarity to OMNI:VCA0423; match to protein family HMM PF05016; hypothetical protein 413630 11727883 BSVBI22_A0408 Brucella suis VBI22 hypothetical protein YP_005154106.1 413313 R 1112912 CDS YP_005154107.1 376280101 11727884 complement(413627..413887) 1 NC_016797.1 identified by similarity to GP:3337067; hypothetical protein 413887 11727884 BSVBI22_A0409 Brucella suis VBI22 hypothetical protein YP_005154107.1 413627 R 1112912 CDS YP_005154108.1 376280102 11727885 complement(413996..414169) 1 NC_016797.1 hypothetical protein 414169 11727885 BSVBI22_A0410 Brucella suis VBI22 hypothetical protein YP_005154108.1 413996 R 1112912 CDS YP_005154109.1 376280103 11727886 414198..414764 1 NC_016797.1 identified by similarity to GP:15155604; hypothetical protein 414764 11727886 BSVBI22_A0411 Brucella suis VBI22 hypothetical protein YP_005154109.1 414198 D 1112912 CDS YP_005154110.1 376280104 11727887 complement(414907..415659) 1 NC_016797.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 415659 11727887 BSVBI22_A0412 Brucella suis VBI22 enoyl-CoA hydratase YP_005154110.1 414907 R 1112912 CDS YP_005154111.1 376280105 11727888 complement(415662..417440) 1 NC_016797.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase family protein 417440 11727888 BSVBI22_A0413 Brucella suis VBI22 acyl-CoA dehydrogenase family protein YP_005154111.1 415662 R 1112912 CDS YP_005154112.1 376280106 11727890 complement(418921..420204) 1 NC_016797.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 420204 purD 11727890 purD Brucella suis VBI22 phosphoribosylamine--glycine ligase YP_005154112.1 418921 R 1112912 CDS YP_005154113.1 376280107 11727891 420349..421350 1 NC_016797.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 421350 ubiA 11727891 ubiA Brucella suis VBI22 4-hydroxybenzoate polyprenyltransferase YP_005154113.1 420349 D 1112912 CDS YP_005154114.1 376280108 11727892 complement(421390..422016) 1 NC_016797.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 422016 pdxH 11727892 pdxH Brucella suis VBI22 pyridoxamine 5'-phosphate oxidase YP_005154114.1 421390 R 1112912 CDS YP_005154115.1 376280109 11727893 422275..422745 1 NC_016797.1 identified by similarity to GP:14026958; hypothetical protein 422745 11727893 BSVBI22_A0418 Brucella suis VBI22 hypothetical protein YP_005154115.1 422275 D 1112912 CDS YP_005154116.1 376280110 11727894 422890..423831 1 NC_016797.1 identified by match to protein family HMM PF00226; match to protein family HMM PF01556; chaperone protein DnaJ 423831 11727894 BSVBI22_A0419 Brucella suis VBI22 chaperone protein DnaJ YP_005154116.1 422890 D 1112912 CDS YP_005154117.1 376280111 11727895 complement(423835..423942) 1 NC_016797.1 hypothetical protein 423942 11727895 BSVBI22_A0420 Brucella suis VBI22 hypothetical protein YP_005154117.1 423835 R 1112912 CDS YP_005154118.1 376280112 11727896 423975..424793 1 NC_016797.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 424793 fabI-1 11727896 fabI-1 Brucella suis VBI22 enoyl-ACP reductase YP_005154118.1 423975 D 1112912 CDS YP_005154119.1 376280113 11727898 complement(425623..425802) 1 NC_016797.1 hypothetical protein 425802 11727898 BSVBI22_A0423 Brucella suis VBI22 hypothetical protein YP_005154119.1 425623 R 1112912 CDS YP_005154120.1 376280114 11727900 complement(426056..426205) 1 NC_016797.1 hypothetical protein 426205 11727900 BSVBI22_A0425 Brucella suis VBI22 hypothetical protein YP_005154120.1 426056 R 1112912 CDS YP_005154121.1 376280115 11727901 426461..426640 1 NC_016797.1 identified by similarity to GP:15160282; hypothetical protein 426640 11727901 BSVBI22_A0426 Brucella suis VBI22 hypothetical protein YP_005154121.1 426461 D 1112912 CDS YP_005154122.1 376280116 11727902 426735..427397 1 NC_016797.1 identified by similarity to GP:14027592; match to protein family HMM PF04028; hypothetical protein 427397 11727902 BSVBI22_A0427 Brucella suis VBI22 hypothetical protein YP_005154122.1 426735 D 1112912 CDS YP_005154123.1 376280117 11727903 complement(427542..427793) 1 NC_016797.1 identified by similarity to GP:15073831; hypothetical protein 427793 11727903 BSVBI22_A0428 Brucella suis VBI22 hypothetical protein YP_005154123.1 427542 R 1112912 CDS YP_005154124.1 376280118 11727904 428069..429163 1 NC_016797.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 429163 aroC 11727904 aroC Brucella suis VBI22 chorismate synthase YP_005154124.1 428069 D 1112912 CDS YP_005154125.1 376280119 11727905 429299..430414 1 NC_016797.1 identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00506; 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II 430414 ribAB 11727905 ribAB Brucella suis VBI22 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II YP_005154125.1 429299 D 1112912 CDS YP_005154126.1 376280120 11727906 430567..431580 1 NC_016797.1 identified by match to protein family HMM PF00850; histone deacetylase family protein 431580 11727906 BSVBI22_A0431 Brucella suis VBI22 histone deacetylase family protein YP_005154126.1 430567 D 1112912 CDS YP_005154127.1 376280121 11727907 431585..431839 1 NC_016797.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 431839 xseB 11727907 xseB Brucella suis VBI22 exodeoxyribonuclease VII small subunit YP_005154127.1 431585 D 1112912 CDS YP_005154128.1 376280122 11727908 complement(431846..432364) 1 NC_016797.1 identified by match to protein family HMM PF00597; dedA family protein 432364 11727908 BSVBI22_A0433 Brucella suis VBI22 dedA family protein YP_005154128.1 431846 R 1112912 CDS YP_005154129.1 376280123 11727909 complement(432606..432866) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3629; match to protein family HMM PF04226; transglycosylase 432866 11727909 BSVBI22_A0434 Brucella suis VBI22 transglycosylase YP_005154129.1 432606 R 1112912 CDS YP_005154130.1 376280124 11727910 433029..433580 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3630; hypothetical protein 433580 11727910 BSVBI22_A0435 Brucella suis VBI22 hypothetical protein YP_005154130.1 433029 D 1112912 CDS YP_005154131.1 376280125 11727911 433784..434656 1 NC_016797.1 identified by similarity to OMNI:CC3178; match to protein family HMM PF02678; match to protein family HMM PF05726; pirin-related protein 434656 11727911 BSVBI22_A0436 Brucella suis VBI22 pirin-related protein YP_005154131.1 433784 D 1112912 CDS YP_005154132.1 376280126 11727912 434799..436730 1 NC_016797.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 436730 dxs 11727912 dxs Brucella suis VBI22 1-deoxy-D-xylulose-5-phosphate synthase YP_005154132.1 434799 D 1112912 CDS YP_005154133.1 376280127 11727913 436736..437497 1 NC_016797.1 identified by similarity to EGAD:20008; match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478; hemolysin A 437497 tlyA 11727913 tlyA Brucella suis VBI22 hemolysin A YP_005154133.1 436736 D 1112912 CDS YP_005154134.1 376280128 11727914 437494..438741 1 NC_016797.1 RNA methyltransferase 438741 11727914 BSVBI22_A0439 Brucella suis VBI22 RNA methyltransferase YP_005154134.1 437494 D 1112912 CDS YP_005154135.1 376280129 11727915 complement(438861..439463) 1 NC_016797.1 identified by similarity to GP:15074050; match to protein family HMM PF03641; match to protein family HMM TIGR00730; hypothetical protein 439463 11727915 BSVBI22_A0440 Brucella suis VBI22 hypothetical protein YP_005154135.1 438861 R 1112912 CDS YP_005154136.1 376280130 11727916 439593..439958 1 NC_016797.1 identified by similarity to GP:15157092; hypothetical protein 439958 11727916 BSVBI22_A0441 Brucella suis VBI22 hypothetical protein YP_005154136.1 439593 D 1112912 CDS YP_005154137.1 376280131 11727917 440145..441359 1 NC_016797.1 identified by match to protein family HMM PF01476; LysM domain-containing protein 441359 11727917 BSVBI22_A0442 Brucella suis VBI22 LysM domain-containing protein YP_005154137.1 440145 D 1112912 CDS YP_005154138.1 376280132 11727918 441562..443448 1 NC_016797.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 443448 11727918 BSVBI22_A0443 Brucella suis VBI22 ABC transporter ATP-binding protein/permease YP_005154138.1 441562 D 1112912 CDS YP_005154139.1 376280133 11727919 443553..444251 1 NC_016797.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 444251 11727919 BSVBI22_A0444 Brucella suis VBI22 phosphatidylserine decarboxylase YP_005154139.1 443553 D 1112912 CDS YP_005154140.1 376280134 11727920 444256..445092 1 NC_016797.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473; CDP-diacylglycerol--serine O-phosphatidyltransferase 445092 pssA 11727920 pssA Brucella suis VBI22 CDP-diacylglycerol--serine O-phosphatidyltransferase YP_005154140.1 444256 D 1112912 CDS YP_005154141.1 376280135 11727921 complement(445177..445917) 1 NC_016797.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 445917 11727921 BSVBI22_A0446 Brucella suis VBI22 short chain dehydrogenase/reductase family oxidoreductase YP_005154141.1 445177 R 1112912 CDS YP_005154142.1 376280136 11727922 complement(445986..447443) 1 NC_016797.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 447443 purF 11727922 purF Brucella suis VBI22 amidophosphoribosyltransferase YP_005154142.1 445986 R 1112912 CDS YP_005154143.1 376280137 11727923 447420..447662 1 NC_016797.1 hypothetical protein 447662 11727923 BSVBI22_A0448 Brucella suis VBI22 hypothetical protein YP_005154143.1 447420 D 1112912 CDS YP_005154144.1 376280138 11727924 complement(447758..448336) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6179; match to protein family HMM PF02674; colicin V production protein 448336 11727924 BSVBI22_A0449 Brucella suis VBI22 colicin V production protein YP_005154144.1 447758 R 1112912 CDS YP_005154145.1 376280139 11727925 complement(448462..449865) 1 NC_016797.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 449865 radA 11727925 radA Brucella suis VBI22 DNA repair protein RadA YP_005154145.1 448462 R 1112912 CDS YP_005154146.1 376280140 11727926 complement(449893..451398) 1 NC_016797.1 unwinds double stranded DNA; replicative DNA helicase 451398 dnaB 11727926 dnaB Brucella suis VBI22 replicative DNA helicase YP_005154146.1 449893 R 1112912 CDS YP_005154147.1 376280141 11727927 complement(451597..452877) 1 NC_016797.1 identified by similarity to SP:P30010; match to protein family HMM PF02353; cyclopropane-fatty-acyl-phospholipid synthase 452877 cfa 11727927 cfa Brucella suis VBI22 cyclopropane-fatty-acyl-phospholipid synthase YP_005154147.1 451597 R 1112912 CDS YP_005154148.1 376280142 11727928 complement(453251..453820) 1 NC_016797.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 453820 rplI 11727928 rplI Brucella suis VBI22 50S ribosomal protein L9 YP_005154148.1 453251 R 1112912 CDS YP_005154149.1 376280143 11727929 complement(453850..454821) 1 NC_016797.1 identified by similarity to GP:15074068; hypothetical protein 454821 11727929 BSVBI22_A0454 Brucella suis VBI22 hypothetical protein YP_005154149.1 453850 R 1112912 CDS YP_005154150.1 376280144 11727930 complement(454972..455220) 1 NC_016797.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 455220 rpsR 11727930 rpsR Brucella suis VBI22 30S ribosomal protein S18 YP_005154150.1 454972 R 1112912 CDS YP_005154151.1 376280145 11727931 complement(455223..455669) 1 NC_016797.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 455669 rpsF 11727931 rpsF Brucella suis VBI22 30S ribosomal protein S6 YP_005154151.1 455223 R 1112912 CDS YP_005154152.1 376280146 11727932 complement(455694..456053) 1 NC_016797.1 identified by similarity to OMNI:VC2163; hypothetical protein 456053 11727932 BSVBI22_A0457 Brucella suis VBI22 hypothetical protein YP_005154152.1 455694 R 1112912 CDS YP_005154153.1 376280147 11727933 456075..457019 1 NC_016797.1 identified by similarity to EGAD:97846; match to protein family HMM PF00698; match to protein family HMM TIGR00128; acyl-carrier-protein S-malonyltransferase 457019 fabD 11727933 fabD Brucella suis VBI22 acyl-carrier-protein S-malonyltransferase YP_005154153.1 456075 D 1112912 CDS YP_005154154.1 376280148 11727934 457089..457826 1 NC_016797.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 457826 fabG 11727934 fabG Brucella suis VBI22 3-ketoacyl-ACP reductase YP_005154154.1 457089 D 1112912 CDS YP_005154155.1 376280149 11727935 458100..458336 1 NC_016797.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 458336 acpP 11727935 acpP Brucella suis VBI22 acyl carrier protein YP_005154155.1 458100 D 1112912 CDS YP_005154156.1 376280150 11727936 458340..458603 1 NC_016797.1 hypothetical protein 458603 11727936 BSVBI22_A0461 Brucella suis VBI22 hypothetical protein YP_005154156.1 458340 D 1112912 CDS YP_005154157.1 376280151 11727937 458660..459922 1 NC_016797.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 459922 fabF 11727937 fabF Brucella suis VBI22 3-oxoacyl-(acyl carrier protein) synthase II YP_005154157.1 458660 D 1112912 CDS YP_005154158.1 376280152 11727938 460147..461385 1 NC_016797.1 identified by similarity to GP:15074077; match to protein family HMM PF02618; match to protein family HMM TIGR00247; hypothetical protein 461385 11727938 BSVBI22_A0463 Brucella suis VBI22 hypothetical protein YP_005154158.1 460147 D 1112912 CDS YP_005154159.1 376280153 11727939 461571..462470 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6198; match to protein family HMM PF03755; match to protein family HMM TIGR00255; hypothetical protein 462470 11727939 BSVBI22_A0464 Brucella suis VBI22 hypothetical protein YP_005154159.1 461571 D 1112912 CDS YP_005154160.1 376280154 11727940 462479..463141 1 NC_016797.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 463141 gmk 11727940 gmk Brucella suis VBI22 guanylate kinase YP_005154160.1 462479 D 1112912 CDS YP_005154161.1 376280155 11727941 complement(463168..464580) 1 NC_016797.1 identified by similarity to EGAD:30245; match to protein family HMM PF01523; TldD protein 464580 11727941 BSVBI22_A0466 Brucella suis VBI22 TldD protein YP_005154161.1 463168 R 1112912 CDS YP_005154162.1 376280156 11727942 complement(464722..465318) 1 NC_016797.1 identified by similarity to GP:15073834; hypothetical protein 465318 11727942 BSVBI22_A0467 Brucella suis VBI22 hypothetical protein YP_005154162.1 464722 R 1112912 CDS YP_005154163.1 376280157 11727943 465782..466636 1 NC_016797.1 identified by similarity to EGAD:8295; match to protein family HMM PF00116; match to protein family HMM PF02790; cytochrome c oxidase subunit II 466636 coxB 11727943 coxB Brucella suis VBI22 cytochrome c oxidase subunit II YP_005154163.1 465782 D 1112912 CDS YP_005154164.1 376280158 11727944 466774..468432 1 NC_016797.1 identified by similarity to EGAD:5976; match to protein family HMM PF00115; cytochrome c oxidase subunit I 468432 coxA 11727944 coxA Brucella suis VBI22 cytochrome c oxidase subunit I YP_005154164.1 466774 D 1112912 CDS YP_005154165.1 376280159 11727945 468660..469607 1 NC_016797.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 469607 ctaB 11727945 ctaB Brucella suis VBI22 protoheme IX farnesyltransferase YP_005154165.1 468660 D 1112912 CDS YP_005154166.1 376280160 11727946 469607..469792 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5908; hypothetical protein 469792 11727946 BSVBI22_A0471 Brucella suis VBI22 hypothetical protein YP_005154166.1 469607 D 1112912 CDS YP_005154167.1 376280161 11727947 469812..470417 1 NC_016797.1 involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 470417 ctaG 11727947 ctaG Brucella suis VBI22 cytochrome C oxidase assembly protein YP_005154167.1 469812 D 1112912 CDS YP_005154168.1 376280162 11727948 470626..471504 1 NC_016797.1 identified by match to protein family HMM PF00510; cytochrome c oxidase subunit III 471504 coxC 11727948 coxC Brucella suis VBI22 cytochrome c oxidase subunit III YP_005154168.1 470626 D 1112912 CDS YP_005154169.1 376280163 11727949 471618..472001 1 NC_016797.1 identified by similarity to GP:14026992; hypothetical protein 472001 11727949 BSVBI22_A0474 Brucella suis VBI22 hypothetical protein YP_005154169.1 471618 D 1112912 CDS YP_005154170.1 376280164 11727950 471998..472747 1 NC_016797.1 identified by match to protein family HMM PF02104; SurF1 family protein 472747 11727950 BSVBI22_A0475 Brucella suis VBI22 SurF1 family protein YP_005154170.1 471998 D 1112912 CDS YP_005154171.1 376280165 11727951 472778..473896 1 NC_016797.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 473896 ispH 11727951 ispH Brucella suis VBI22 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_005154171.1 472778 D 1112912 CDS YP_005154172.1 376280166 11727952 473902..474882 1 NC_016797.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine; homoserine kinase 474882 thrB 11727952 thrB Brucella suis VBI22 homoserine kinase YP_005154172.1 473902 D 1112912 CDS YP_005154173.1 376280167 11727953 474879..475343 1 NC_016797.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 475343 rnhA 11727953 rnhA Brucella suis VBI22 ribonuclease H YP_005154173.1 474879 D 1112912 CDS YP_005154174.1 376280168 11727954 complement(475373..475858) 1 NC_016797.1 identified by match to protein family HMM PF00578; ahpC/TSA family protein 475858 11727954 BSVBI22_A0479 Brucella suis VBI22 ahpC/TSA family protein YP_005154174.1 475373 R 1112912 CDS YP_005154175.1 376280169 11727955 complement(476038..476838) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5920; hypothetical protein 476838 11727955 BSVBI22_A0480 Brucella suis VBI22 hypothetical protein YP_005154175.1 476038 R 1112912 CDS YP_005154176.1 376280170 11727956 476973..477575 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5921; match to protein family HMM PF02622; hypothetical protein 477575 11727956 BSVBI22_A0481 Brucella suis VBI22 hypothetical protein YP_005154176.1 476973 D 1112912 CDS YP_005154177.1 376280171 11727957 complement(477673..480567) 1 NC_016797.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00785; match to protein family HMM PF00990; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; sensory box protein 480567 11727957 BSVBI22_A0482 Brucella suis VBI22 sensory box protein YP_005154177.1 477673 R 1112912 CDS YP_005154178.1 376280172 11727958 complement(480564..481184) 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 481184 11727958 BSVBI22_A0483 Brucella suis VBI22 acetyltransferase YP_005154178.1 480564 R 1112912 CDS YP_005154179.1 376280173 11727959 complement(481355..482647) 1 NC_016797.1 identified by similarity to OMNI:NTL01BH2408; match to protein family HMM PF00675; match to protein family HMM PF05193; processing protease 482647 11727959 BSVBI22_A0484 Brucella suis VBI22 processing protease YP_005154179.1 481355 R 1112912 CDS YP_005154180.1 376280174 11727960 complement(482701..484092) 1 NC_016797.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 484092 thrC 11727960 thrC Brucella suis VBI22 threonine synthase YP_005154180.1 482701 R 1112912 CDS YP_005154181.1 376280175 11727961 complement(484172..484363) 1 NC_016797.1 hypothetical protein 484363 11727961 BSVBI22_A0486 Brucella suis VBI22 hypothetical protein YP_005154181.1 484172 R 1112912 CDS YP_005154182.1 376280176 11727962 484514..485092 1 NC_016797.1 putative lipoprotein 485092 11727962 BSVBI22_A0487 Brucella suis VBI22 putative lipoprotein YP_005154182.1 484514 D 1112912 CDS YP_005154183.1 376280177 11727963 485406..487040 1 NC_016797.1 identified by similarity to OMNI:NTL03PA02200; match to protein family HMM PF00563; EAL domain-containing protein 487040 11727963 BSVBI22_A0488 Brucella suis VBI22 EAL domain-containing protein YP_005154183.1 485406 D 1112912 CDS YP_005154184.1 376280178 11727964 487169..487354 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1736; hypothetical protein 487354 11727964 BSVBI22_A0489 Brucella suis VBI22 hypothetical protein YP_005154184.1 487169 D 1112912 CDS YP_005154185.1 376280179 11727965 complement(487396..488082) 1 NC_016797.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD superfamily hydrolase 488082 11727965 BSVBI22_A0490 Brucella suis VBI22 HAD superfamily hydrolase YP_005154185.1 487396 R 1112912 CDS YP_005154186.1 376280180 11727966 complement(488230..490020) 1 NC_016797.1 identified by match to protein family HMM PF00654; voltage gated chloride channel family protein 490020 11727966 BSVBI22_A0491 Brucella suis VBI22 voltage gated chloride channel family protein YP_005154186.1 488230 R 1112912 CDS YP_005154187.1 376280181 11727967 490357..491490 1 NC_016797.1 identified by similarity to EGAD:154344; match to protein family HMM PF01555; modification methylase BabI 491490 babI 11727967 babI Brucella suis VBI22 modification methylase BabI YP_005154187.1 490357 D 1112912 CDS YP_005154188.1 376280182 11727968 complement(491573..492190) 1 NC_016797.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; HAD superfamily hydrolase 492190 11727968 BSVBI22_A0493 Brucella suis VBI22 HAD superfamily hydrolase YP_005154188.1 491573 R 1112912 CDS YP_005154189.1 376280183 11727969 complement(492187..493263) 1 NC_016797.1 identified by similarity to EGAD:19424; match to protein family HMM PF00730; match to protein family HMM TIGR01084; A/G-specific adenine glycosylase 493263 mutY 11727969 mutY Brucella suis VBI22 A/G-specific adenine glycosylase YP_005154189.1 492187 R 1112912 CDS YP_005154190.1 376280184 11727970 493537..494064 1 NC_016797.1 identified by similarity to GP:15073860; hypothetical protein 494064 11727970 BSVBI22_A0495 Brucella suis VBI22 hypothetical protein YP_005154190.1 493537 D 1112912 CDS YP_005154191.1 376280185 11727971 494082..494255 1 NC_016797.1 hypothetical protein 494255 11727971 BSVBI22_A0496 Brucella suis VBI22 hypothetical protein YP_005154191.1 494082 D 1112912 CDS YP_005154192.1 376280186 11727972 494302..494955 1 NC_016797.1 identified by similarity to GP:15155781; match to protein family HMM PF01323; match to protein family HMM TIGR01409; twin-arginine translocation pathway signal sequence domain-containing protein 494955 11727972 BSVBI22_A0497 Brucella suis VBI22 twin-arginine translocation pathway signal sequence domain-containing protein YP_005154192.1 494302 D 1112912 CDS YP_005154193.1 376280187 11727973 495034..498492 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5933; match to protein family HMM PF02463; match to protein family HMM PF02483; match to protein family HMM TIGR02168; SMC family protein 498492 11727973 BSVBI22_A0498 Brucella suis VBI22 SMC family protein YP_005154193.1 495034 D 1112912 CDS YP_005154194.1 376280188 11727974 498515..499408 1 NC_016797.1 identified by similarity to SP:P13512; match to protein family HMM PF01545; match to protein family HMM TIGR01297; cobalt-zinc-cadmium resistance protein 499408 11727974 BSVBI22_A0499 Brucella suis VBI22 cobalt-zinc-cadmium resistance protein YP_005154194.1 498515 D 1112912 CDS YP_005154195.1 376280189 11727975 complement(499518..499859) 1 NC_016797.1 identified by match to protein family HMM PF00903; glyoxalase family protein 499859 11727975 BSVBI22_A0500 Brucella suis VBI22 glyoxalase family protein YP_005154195.1 499518 R 1112912 CDS YP_005154196.1 376280190 11727976 500123..502786 1 NC_016797.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 502786 ppdK 11727976 ppdK Brucella suis VBI22 pyruvate phosphate dikinase YP_005154196.1 500123 D 1112912 CDS YP_005154197.1 376280191 11727978 complement(504062..504208) 1 NC_016797.1 hypothetical protein 504208 11727978 BSVBI22_A0503 Brucella suis VBI22 hypothetical protein YP_005154197.1 504062 R 1112912 CDS YP_005154198.1 376280192 11727979 complement(504205..504534) 1 NC_016797.1 hypothetical protein 504534 11727979 BSVBI22_A0504 Brucella suis VBI22 hypothetical protein YP_005154198.1 504205 R 1112912 CDS YP_005154199.1 376280193 11727980 504818..505606 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5941; hypothetical protein 505606 11727980 BSVBI22_A0505 Brucella suis VBI22 hypothetical protein YP_005154199.1 504818 D 1112912 CDS YP_005154200.1 376280194 11727981 complement(505607..506512) 1 NC_016797.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 506512 11727981 BSVBI22_A0506 Brucella suis VBI22 metallo-beta-lactamase family protein YP_005154200.1 505607 R 1112912 CDS YP_005154201.1 376280195 11727982 506713..507312 1 NC_016797.1 identified by match to protein family HMM PF02632; BioY family protein 507312 11727982 BSVBI22_A0507 Brucella suis VBI22 BioY family protein YP_005154201.1 506713 D 1112912 CDS YP_005154202.1 376280196 11727983 507466..507975 1 NC_016797.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 507975 11727983 BSVBI22_A0508 Brucella suis VBI22 ureidoglycolate hydrolase YP_005154202.1 507466 D 1112912 CDS YP_005154203.1 376280197 11727984 507987..508343 1 NC_016797.1 identified by similarity to GP:15157490; match to protein family HMM PF00576; hypothetical protein 508343 11727984 BSVBI22_A0509 Brucella suis VBI22 hypothetical protein YP_005154203.1 507987 D 1112912 CDS YP_005154204.1 376280198 11727985 508414..509250 1 NC_016797.1 identified by similarity to GP:15157607; hypothetical protein 509250 11727985 BSVBI22_A0510 Brucella suis VBI22 hypothetical protein YP_005154204.1 508414 D 1112912 CDS YP_005154205.1 376280199 11727986 509787..511655 1 NC_016797.1 identified by similarity to GP:6009656; match to protein family HMM PF02719; epimerase/dehydratase 511655 11727986 BSVBI22_A0511 Brucella suis VBI22 epimerase/dehydratase YP_005154205.1 509787 D 1112912 CDS YP_005154206.1 376280200 11727987 complement(511642..512649) 1 NC_016797.1 identified by match to protein family HMM PF00953; glycoside hydrolase family protein 512649 11727987 BSVBI22_A0512 Brucella suis VBI22 glycoside hydrolase family protein YP_005154206.1 511642 R 1112912 CDS YP_005154207.1 376280201 11727989 513308..514126 1 NC_016797.1 transposase 514126 11727989 BSVBI22_A0513 Brucella suis VBI22 transposase YP_005154207.1 513308 D 1112912 CDS YP_005154208.1 376280202 11727990 514502..514801 1 NC_016797.1 transposase 514801 11727990 BSVBI22_A0514 Brucella suis VBI22 transposase YP_005154208.1 514502 D 1112912 CDS YP_005154209.1 376280203 11727991 515317..516180 1 NC_016797.1 transposase 516180 11727991 BSVBI22_A0515 Brucella suis VBI22 transposase YP_005154209.1 515317 D 1112912 CDS YP_005154210.1 376280204 11727992 complement(516518..517297) 1 NC_016797.1 identified by match to protein family HMM PF00551; formyltransferase 517297 11727992 BSVBI22_A0516 Brucella suis VBI22 formyltransferase YP_005154210.1 516518 R 1112912 CDS YP_005154211.1 376280205 11727993 complement(517324..518178) 1 NC_016797.1 identified by similarity to GP:4071215; wbkB protein 518178 wbkB 11727993 wbkB Brucella suis VBI22 wbkB protein YP_005154211.1 517324 R 1112912 CDS YP_005154212.1 376280206 11727994 complement(518175..518933) 1 NC_016797.1 identified by similarity to SP:Q56903; match to protein family HMM PF00005; O-antigen export system ATP-binding protein RfbE 518933 rfbE 11727994 rfbE Brucella suis VBI22 O-antigen export system ATP-binding protein RfbE YP_005154212.1 518175 R 1112912 CDS YP_005154213.1 376280207 11727995 complement(518930..519712) 1 NC_016797.1 identified by similarity to SP:Q56902; match to protein family HMM PF01061; O-antigen export system permease protein RfbD 519712 rfbD 11727995 rfbD Brucella suis VBI22 O-antigen export system permease protein RfbD YP_005154213.1 518930 R 1112912 CDS YP_005154214.1 376280208 11727996 complement(519727..520830) 1 NC_016797.1 identified by similarity to EGAD:15706; match to protein family HMM PF01041; perosamine synthase 520830 11727996 BSVBI22_A0520 Brucella suis VBI22 perosamine synthase YP_005154214.1 519727 R 1112912 CDS YP_005154215.1 376280209 11727997 complement(520838..521926) 1 NC_016797.1 identified by similarity to EGAD:11583; match to protein family HMM TIGR01472; GDP-mannose 4,6-dehydratase 521926 gmd 11727997 gmd Brucella suis VBI22 GDP-mannose 4,6-dehydratase YP_005154215.1 520838 R 1112912 CDS YP_005154216.1 376280210 11727998 522445..522873 1 NC_016797.1 identified by similarity to GP:4071219; ISBm1, transposase orfA 522873 11727998 BSVBI22_A0522 Brucella suis VBI22 ISBm1, transposase orfA YP_005154216.1 522445 D 1112912 CDS YP_005154217.1 376280211 11727999 523196..523990 1 NC_016797.1 integrase catalytic subunit 523990 11727999 BSVBI22_A0523 Brucella suis VBI22 integrase catalytic subunit YP_005154217.1 523196 D 1112912 CDS YP_005154218.1 376280212 11728000 524082..524393 1 NC_016797.1 identified by similarity to EGAD:46813; IS711, transposase orfA 524393 11728000 BSVBI22_A0524 Brucella suis VBI22 IS711, transposase orfA YP_005154218.1 524082 D 1112912 CDS YP_005154219.1 376280213 11728001 524425..524817 1 NC_016797.1 identified by similarity to PIR:PN0685; match to protein family HMM PF01609; IS711, transposase orfB 524817 11728001 BSVBI22_A0525 Brucella suis VBI22 IS711, transposase orfB YP_005154219.1 524425 D 1112912 CDS YP_005154220.1 376280214 11728002 525188..526306 1 NC_016797.1 identified by match to protein family HMM PF00534; mannosyltransferase 526306 11728002 BSVBI22_A0526 Brucella suis VBI22 mannosyltransferase YP_005154220.1 525188 D 1112912 CDS YP_005154221.1 376280215 11728003 526364..526732 1 NC_016797.1 identified by similarity to EGAD:36179; IS5 family transposase orfA 526732 11728003 BSVBI22_A0527 Brucella suis VBI22 IS5 family transposase orfA YP_005154221.1 526364 D 1112912 CDS YP_005154222.1 376280216 11728004 526828..527169 1 NC_016797.1 identified by similarity to GP:482819; IS5 family transposase orfB 527169 11728004 BSVBI22_A0528 Brucella suis VBI22 IS5 family transposase orfB YP_005154222.1 526828 D 1112912 CDS YP_005154223.1 376280217 11728006 527978..528406 1 NC_016797.1 identified by similarity to GP:4071219; ISBm1, transposase orfA 528406 11728006 BSVBI22_A0530 Brucella suis VBI22 ISBm1, transposase orfA YP_005154223.1 527978 D 1112912 CDS YP_005154224.1 376280218 11728007 528325..528741 1 NC_016797.1 identified by similarity to GP:4071222; match to protein family HMM PF01609; ISBm1, transposase orfB 528741 11728007 BSVBI22_A0531 Brucella suis VBI22 ISBm1, transposase orfB YP_005154224.1 528325 D 1112912 CDS YP_005154225.1 376280219 11728009 529633..530970 1 NC_016797.1 identified by similarity to EGAD:8806; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase 530970 11728009 BSVBI22_A0533 Brucella suis VBI22 phosphomannomutase YP_005154225.1 529633 D 1112912 CDS YP_005154226.1 376280220 11728010 530995..532419 1 NC_016797.1 identified by similarity to EGAD:97081; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM TIGR01479; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 532419 11728010 BSVBI22_A0534 Brucella suis VBI22 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_005154226.1 530995 D 1112912 CDS YP_005154227.1 376280221 11728011 532452..533624 1 NC_016797.1 identified by similarity to SP:P29954; mannose-6-phosphate isomerase 533624 manA 11728011 manA Brucella suis VBI22 mannose-6-phosphate isomerase YP_005154227.1 532452 D 1112912 CDS YP_005154228.1 376280222 11728012 533707..534816 1 NC_016797.1 identified by similarity to GP:3249553; match to protein family HMM PF00534; glycoside hydrolase family protein 534816 11728012 BSVBI22_A0536 Brucella suis VBI22 glycoside hydrolase family protein YP_005154228.1 533707 D 1112912 CDS YP_005154229.1 376280223 11728013 complement(535297..535509) 1 NC_016797.1 hypothetical protein 535509 11728013 BSVBI22_A0537 Brucella suis VBI22 hypothetical protein YP_005154229.1 535297 R 1112912 CDS YP_005154230.1 376280224 11728014 535508..537043 1 NC_016797.1 identified by similarity to SP:P04983; match to protein family HMM PF00005; ribose ABC transporter ATP-binding protein 537043 rbsA-1 11728014 rbsA-1 Brucella suis VBI22 ribose ABC transporter ATP-binding protein YP_005154230.1 535508 D 1112912 CDS YP_005154231.1 376280225 11728015 537064..538065 1 NC_016797.1 identified by similarity to SP:P36948; match to protein family HMM PF02653; ribose ABC transporter permease 538065 rbsC-1 11728015 rbsC-1 Brucella suis VBI22 ribose ABC transporter permease YP_005154231.1 537064 D 1112912 CDS YP_005154232.1 376280226 11728016 538144..539106 1 NC_016797.1 identified by similarity to SP:P02926; match to protein family HMM PF00532; ribose ABC transporter substrate-binding protein 539106 rbsB-1 11728016 rbsB-1 Brucella suis VBI22 ribose ABC transporter substrate-binding protein YP_005154232.1 538144 D 1112912 CDS YP_005154233.1 376280227 11728017 539164..540216 1 NC_016797.1 identified by similarity to GP:15075918; hypothetical protein 540216 11728017 BSVBI22_A0541 Brucella suis VBI22 hypothetical protein YP_005154233.1 539164 D 1112912 CDS YP_005154234.1 376280228 11728018 540224..541396 1 NC_016797.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 541396 11728018 BSVBI22_A0542 Brucella suis VBI22 Gfo/Idh/MocA family oxidoreductase YP_005154234.1 540224 D 1112912 CDS YP_005154235.1 376280229 11728019 complement(541438..542745) 1 NC_016797.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 542745 xylA 11728019 xylA Brucella suis VBI22 xylose isomerase YP_005154235.1 541438 R 1112912 CDS YP_005154236.1 376280230 11728020 complement(542792..544243) 1 NC_016797.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312; xylulokinase 544243 xylB 11728020 xylB Brucella suis VBI22 xylulokinase YP_005154236.1 542792 R 1112912 CDS YP_005154237.1 376280231 11728021 complement(544276..545307) 1 NC_016797.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcriptional regulator 545307 11728021 BSVBI22_A0545 Brucella suis VBI22 LacI family transcriptional regulator YP_005154237.1 544276 R 1112912 CDS YP_005154238.1 376280232 11728022 complement(545569..546639) 1 NC_016797.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 546639 11728022 BSVBI22_A0546 Brucella suis VBI22 AraC family transcriptional regulator YP_005154238.1 545569 R 1112912 CDS YP_005154239.1 376280233 11728023 complement(547011..547118) 1 NC_016797.1 hypothetical protein 547118 11728023 BSVBI22_A0547 Brucella suis VBI22 hypothetical protein YP_005154239.1 547011 R 1112912 CDS YP_005154240.1 376280234 11728024 complement(547178..548641) 1 NC_016797.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 548641 betB 11728024 betB Brucella suis VBI22 betaine aldehyde dehydrogenase YP_005154240.1 547178 R 1112912 CDS YP_005154241.1 376280235 11728025 complement(548827..550476) 1 NC_016797.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 550476 betA 11728025 betA Brucella suis VBI22 choline dehydrogenase YP_005154241.1 548827 R 1112912 CDS YP_005154242.1 376280236 11728026 complement(550479..551075) 1 NC_016797.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 551075 betI 11728026 betI Brucella suis VBI22 transcriptional regulator BetI YP_005154242.1 550479 R 1112912 CDS YP_005154243.1 376280237 11728027 551266..552288 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6007; hypothetical protein 552288 11728027 BSVBI22_A0551 Brucella suis VBI22 hypothetical protein YP_005154243.1 551266 D 1112912 CDS YP_005154244.1 376280238 11728028 552333..552803 1 NC_016797.1 identified by match to protein family HMM PF01272; transcription elongation factor GreA domain-containing protein 552803 11728028 BSVBI22_A0552 Brucella suis VBI22 transcription elongation factor GreA domain-containing protein YP_005154244.1 552333 D 1112912 CDS YP_005154245.1 376280239 11728029 complement(552800..553189) 1 NC_016797.1 identified by similarity to EGAD:69439; match to protein family HMM PF05012; match to protein family HMM TIGR01550; death-on-curing family protein 553189 11728029 BSVBI22_A0553 Brucella suis VBI22 death-on-curing family protein YP_005154245.1 552800 R 1112912 CDS YP_005154246.1 376280240 11728030 complement(553186..553416) 1 NC_016797.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439; AbrB family transcriptional regulator 553416 11728030 BSVBI22_A0554 Brucella suis VBI22 AbrB family transcriptional regulator YP_005154246.1 553186 R 1112912 CDS YP_005154247.1 376280241 11728031 complement(553477..554469) 1 NC_016797.1 identified by similarity to GP:15620053; match to protein family HMM PF01544; CorA family protein 554469 11728031 BSVBI22_A0555 Brucella suis VBI22 CorA family protein YP_005154247.1 553477 R 1112912 CDS YP_005154248.1 376280242 11728032 554625..555638 1 NC_016797.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 555638 11728032 BSVBI22_A0556 Brucella suis VBI22 GntR family transcriptional regulator YP_005154248.1 554625 D 1112912 CDS YP_005154249.1 376280243 11728033 555460..556608 1 NC_016797.1 cyanate transport system protein CynX 556608 11728033 BSVBI22_A0557 Brucella suis VBI22 cyanate transport system protein CynX YP_005154249.1 555460 D 1112912 CDS YP_005154250.1 376280244 11728034 complement(556665..557027) 1 NC_016797.1 identified by similarity to GP:15073896; hypothetical protein 557027 11728034 BSVBI22_A0558 Brucella suis VBI22 hypothetical protein YP_005154250.1 556665 R 1112912 CDS YP_005154251.1 376280245 11728035 557363..558874 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6012; match to protein family HMM PF05872; hypothetical protein 558874 11728035 BSVBI22_A0559 Brucella suis VBI22 hypothetical protein YP_005154251.1 557363 D 1112912 CDS YP_005154252.1 376280246 11728036 complement(559072..559788) 1 NC_016797.1 identified by similarity to GP:15141233; match to protein family HMM PF03734; match to protein family HMM TIGR01409; hypothetical protein 559788 11728036 BSVBI22_A0560 Brucella suis VBI22 hypothetical protein YP_005154252.1 559072 R 1112912 CDS YP_005154253.1 376280247 11728037 complement(560091..560744) 1 NC_016797.1 identified by similarity to SP:Q51645; match to protein family HMM PF00702; match to protein family HMM TIGR01428; match to protein family HMM TIGR01493; haloacid dehalogenase 560744 11728037 BSVBI22_A0561 Brucella suis VBI22 haloacid dehalogenase YP_005154253.1 560091 R 1112912 CDS YP_005154254.1 376280248 11728038 560967..561566 1 NC_016797.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777; Fe/Mn family superoxide dismutase 561566 11728038 BSVBI22_A0562 Brucella suis VBI22 Fe/Mn family superoxide dismutase YP_005154254.1 560967 D 1112912 CDS YP_005154255.1 376280249 11728039 561612..562187 1 NC_016797.1 hypothetical protein 562187 11728039 BSVBI22_A0563 Brucella suis VBI22 hypothetical protein YP_005154255.1 561612 D 1112912 CDS YP_005154256.1 376280250 11728040 complement(562191..564299) 1 NC_016797.1 identified by similarity to EGAD:17797; match to protein family HMM PF00326; match to protein family HMM PF02897; protease II 564299 ptrB 11728040 ptrB Brucella suis VBI22 protease II YP_005154256.1 562191 R 1112912 CDS YP_005154257.1 376280251 11728041 564872..565300 1 NC_016797.1 identified by similarity to EGAD:35422; match to protein family HMM PF05443; Ros/MucR family transcriptional regulator 565300 11728041 BSVBI22_A0565 Brucella suis VBI22 Ros/MucR family transcriptional regulator YP_005154257.1 564872 D 1112912 CDS YP_005154258.1 376280252 11728042 complement(565508..565756) 1 NC_016797.1 hypothetical protein 565756 11728042 BSVBI22_A0566 Brucella suis VBI22 hypothetical protein YP_005154258.1 565508 R 1112912 CDS YP_005154259.1 376280253 11728043 566001..566456 1 NC_016797.1 hypothetical protein 566456 11728043 BSVBI22_A0567 Brucella suis VBI22 hypothetical protein YP_005154259.1 566001 D 1112912 CDS YP_005154260.1 376280254 11728044 566603..567247 1 NC_016797.1 identified by similarity to GP:15155912; hypothetical protein 567247 11728044 BSVBI22_A0568 Brucella suis VBI22 hypothetical protein YP_005154260.1 566603 D 1112912 CDS YP_005154261.1 376280255 11728045 567359..568582 1 NC_016797.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 568582 11728045 BSVBI22_A0569 Brucella suis VBI22 amidase YP_005154261.1 567359 D 1112912 CDS YP_005154262.1 376280256 11728046 complement(568623..569048) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6032; match to protein family HMM PF02657; hypothetical protein 569048 11728046 BSVBI22_A0570 Brucella suis VBI22 hypothetical protein YP_005154262.1 568623 R 1112912 CDS YP_005154263.1 376280257 11728047 complement(569128..569577) 1 NC_016797.1 identified by similarity to SP:Q52968; hypothetical protein 569577 11728047 BSVBI22_A0571 Brucella suis VBI22 hypothetical protein YP_005154263.1 569128 R 1112912 CDS YP_005154264.1 376280258 11728048 complement(569763..569882) 1 NC_016797.1 hypothetical protein 569882 11728048 BSVBI22_A0572 Brucella suis VBI22 hypothetical protein YP_005154264.1 569763 R 1112912 CDS YP_005154265.1 376280259 11728049 569868..571697 1 NC_016797.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 571697 11728049 BSVBI22_A0573 Brucella suis VBI22 sensor histidine kinase YP_005154265.1 569868 D 1112912 CDS YP_005154266.1 376280260 11728050 571624..572640 1 NC_016797.1 identified by match to protein family HMM PF01471; peptidoglycan-binding protein 572640 11728050 BSVBI22_A0574 Brucella suis VBI22 peptidoglycan-binding protein YP_005154266.1 571624 D 1112912 CDS YP_005154267.1 376280261 11728051 572654..573001 1 NC_016797.1 hypothetical protein 573001 11728051 BSVBI22_A0575 Brucella suis VBI22 hypothetical protein YP_005154267.1 572654 D 1112912 CDS YP_005154268.1 376280262 11728052 complement(573012..574088) 1 NC_016797.1 identified by similarity to GP:15073936; hypothetical protein 574088 11728052 BSVBI22_A0576 Brucella suis VBI22 hypothetical protein YP_005154268.1 573012 R 1112912 CDS YP_005154269.1 376280263 11728053 complement(574286..574828) 1 NC_016797.1 identified by similarity to GP:15073939; hypothetical protein 574828 11728053 BSVBI22_A0577 Brucella suis VBI22 hypothetical protein YP_005154269.1 574286 R 1112912 CDS YP_005154270.1 376280264 11728054 complement(574821..575432) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6040; hypothetical protein 575432 11728054 BSVBI22_A0578 Brucella suis VBI22 hypothetical protein YP_005154270.1 574821 R 1112912 CDS YP_005154271.1 376280265 11728055 complement(575439..577595) 1 NC_016797.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; 1A family penicillin-binding protein 577595 11728055 BSVBI22_A0579 Brucella suis VBI22 1A family penicillin-binding protein YP_005154271.1 575439 R 1112912 CDS YP_005154272.1 376280266 11728056 578016..578465 1 NC_016797.1 hypothetical protein 578465 11728056 BSVBI22_A0580 Brucella suis VBI22 hypothetical protein YP_005154272.1 578016 D 1112912 CDS YP_005154273.1 376280267 11728057 578509..579663 1 NC_016797.1 terminase large subunit 579663 11728057 BSVBI22_A0581 Brucella suis VBI22 terminase large subunit YP_005154273.1 578509 D 1112912 CDS YP_005154274.1 376280268 11728058 579695..580888 1 NC_016797.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; HK97 family portal protein 580888 11728058 BSVBI22_A0582 Brucella suis VBI22 HK97 family portal protein YP_005154274.1 579695 D 1112912 CDS YP_005154275.1 376280269 11728059 580885..581262 1 NC_016797.1 identified by similarity to GP:15155959; hypothetical protein 581262 11728059 BSVBI22_A0583 Brucella suis VBI22 hypothetical protein YP_005154275.1 580885 D 1112912 CDS YP_005154276.1 376280270 11728060 581249..581917 1 NC_016797.1 identified by match to protein family HMM PF04586; match to protein family HMM TIGR01543; protease 581917 11728060 BSVBI22_A0584 Brucella suis VBI22 protease YP_005154276.1 581249 D 1112912 CDS YP_005154277.1 376280271 11728061 581939..583213 1 NC_016797.1 identified by match to protein family HMM TIGR01554; HK97 family major capsid protein 583213 11728061 BSVBI22_A0585 Brucella suis VBI22 HK97 family major capsid protein YP_005154277.1 581939 D 1112912 CDS YP_005154278.1 376280272 11728062 583378..583944 1 NC_016797.1 identified by similarity to GP:15155962; hypothetical protein 583944 11728062 BSVBI22_A0586 Brucella suis VBI22 hypothetical protein YP_005154278.1 583378 D 1112912 CDS YP_005154279.1 376280273 11728063 583941..584279 1 NC_016797.1 identified by similarity to GP:15155963; match to protein family HMM TIGR01563; hypothetical protein 584279 11728063 BSVBI22_A0587 Brucella suis VBI22 hypothetical protein YP_005154279.1 583941 D 1112912 CDS YP_005154280.1 376280274 11728064 584276..584443 1 NC_016797.1 hypothetical protein 584443 11728064 BSVBI22_A0588 Brucella suis VBI22 hypothetical protein YP_005154280.1 584276 D 1112912 CDS YP_005154281.1 376280275 11728065 584403..584810 1 NC_016797.1 identified by similarity to GP:15155964; hypothetical protein 584810 11728065 BSVBI22_A0589 Brucella suis VBI22 hypothetical protein YP_005154281.1 584403 D 1112912 CDS YP_005154282.1 376280276 11728066 584851..585264 1 NC_016797.1 identified by similarity to OMNI:CC2781; match to protein family HMM TIGR02126; hypothetical protein 585264 11728066 BSVBI22_A0590 Brucella suis VBI22 hypothetical protein YP_005154282.1 584851 D 1112912 CDS YP_005154283.1 376280277 11728067 585267..585602 1 NC_016797.1 identified by similarity to GP:15155967; hypothetical protein 585602 11728067 BSVBI22_A0591 Brucella suis VBI22 hypothetical protein YP_005154283.1 585267 D 1112912 CDS YP_005154284.1 376280278 11728069 585821..586366 1 NC_016797.1 identified by similarity to GP:15155972; hypothetical protein 586366 11728069 BSVBI22_A0593 Brucella suis VBI22 hypothetical protein YP_005154284.1 585821 D 1112912 CDS YP_005154285.1 376280279 11728070 586369..587001 1 NC_016797.1 identified by similarity to GP:15155973; hypothetical protein 587001 11728070 BSVBI22_A0594 Brucella suis VBI22 hypothetical protein YP_005154285.1 586369 D 1112912 CDS YP_005154286.1 376280280 11728071 586998..587873 1 NC_016797.1 identified by similarity to GP:15155974; hypothetical protein 587873 11728071 BSVBI22_A0595 Brucella suis VBI22 hypothetical protein YP_005154286.1 586998 D 1112912 CDS YP_005154287.1 376280281 11728072 587870..588304 1 NC_016797.1 identified by match to protein family HMM PF00877; NLP/P60 family protein 588304 11728072 BSVBI22_A0596 Brucella suis VBI22 NLP/P60 family protein YP_005154287.1 587870 D 1112912 CDS YP_005154288.1 376280282 11728074 592228..592434 1 NC_016797.1 identified by similarity to GP:15155977; hypothetical protein 592434 11728074 BSVBI22_A0598 Brucella suis VBI22 hypothetical protein YP_005154288.1 592228 D 1112912 CDS YP_005154289.1 376280283 11728075 592596..592892 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6060; hypothetical protein 592892 11728075 BSVBI22_A0599 Brucella suis VBI22 hypothetical protein YP_005154289.1 592596 D 1112912 CDS YP_005154290.1 376280284 11728076 592971..593660 1 NC_016797.1 identified by similarity to OMNI:CC2766; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 593660 11728076 BSVBI22_A0600 Brucella suis VBI22 DNA-binding response regulator YP_005154290.1 592971 D 1112912 CDS YP_005154291.1 376280285 11728077 593747..595045 1 NC_016797.1 identified by similarity to GP:14027143; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 595045 11728077 BSVBI22_A0601 Brucella suis VBI22 sensor histidine kinase YP_005154291.1 593747 D 1112912 CDS YP_005154292.1 376280286 11728078 595106..595591 1 NC_016797.1 identified by similarity to GP:15073947; outer membrane lipoprotein-related protein 595591 11728078 BSVBI22_A0602 Brucella suis VBI22 outer membrane lipoprotein-related protein YP_005154292.1 595106 D 1112912 CDS YP_005154293.1 376280287 11728079 595692..596831 1 NC_016797.1 cytochrome c-type biogenesis protein 596831 11728079 BSVBI22_A0603 Brucella suis VBI22 cytochrome c-type biogenesis protein YP_005154293.1 595692 D 1112912 CDS YP_005154294.1 376280288 11728080 596828..597325 1 NC_016797.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 597325 ccmE 11728080 ccmE Brucella suis VBI22 cytochrome c-type biogenesis protein CcmE YP_005154294.1 596828 D 1112912 CDS YP_005154295.1 376280289 11728081 597345..599336 1 NC_016797.1 identified by similarity to EGAD:8346; match to protein family HMM PF01578; match to protein family HMM TIGR00353; cytochrome c-type biogenesis protein CcmF 599336 ccmF 11728081 ccmF Brucella suis VBI22 cytochrome c-type biogenesis protein CcmF YP_005154295.1 597345 D 1112912 CDS YP_005154296.1 376280290 11728082 599333..599809 1 NC_016797.1 identified by similarity to SP:P45406; match to protein family HMM PF03918; cytochrome c-type biogenesis protein CcmH 599809 ccmh 11728082 ccmh Brucella suis VBI22 cytochrome c-type biogenesis protein CcmH YP_005154296.1 599333 D 1112912 CDS YP_005154297.1 376280291 11728083 599951..601492 1 NC_016797.1 identified by similarity to EGAD:21403; match to protein family HMM PF00089; match to protein family HMM PF00595; serine protease 601492 11728083 BSVBI22_A0607 Brucella suis VBI22 serine protease YP_005154297.1 599951 D 1112912 CDS YP_005154298.1 376280292 11728084 601586..602293 1 NC_016797.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 602293 11728084 BSVBI22_A0608 Brucella suis VBI22 DNA-binding response regulator YP_005154298.1 601586 D 1112912 CDS YP_005154299.1 376280293 11728085 602293..603696 1 NC_016797.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 603696 11728085 BSVBI22_A0609 Brucella suis VBI22 sensor histidine kinase YP_005154299.1 602293 D 1112912 CDS YP_005154300.1 376280294 11728086 603819..606770 1 NC_016797.1 identified by similarity to EGAD:7704; match to protein family HMM PF03710; glutamate-ammonia-ligase adenylyltransferase 606770 glnE 11728086 glnE Brucella suis VBI22 glutamate-ammonia-ligase adenylyltransferase YP_005154300.1 603819 D 1112912 CDS YP_005154301.1 376280295 11728087 complement(606815..608926) 1 NC_016797.1 identified by similarity to GP:15156909; match to protein family HMM PF01755; match to protein family HMM PF04932; hypothetical protein 608926 11728087 BSVBI22_A0611 Brucella suis VBI22 hypothetical protein YP_005154301.1 606815 R 1112912 CDS YP_005154302.1 376280296 11728088 complement(609197..611548) 1 NC_016797.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00785; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase 611548 11728088 BSVBI22_A0612 Brucella suis VBI22 sensory box histidine kinase YP_005154302.1 609197 R 1112912 CDS YP_005154303.1 376280297 11728089 complement(611939..614590) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6073; match to protein family HMM PF01433; aminopeptidase N 614590 pepN 11728089 pepN Brucella suis VBI22 aminopeptidase N YP_005154303.1 611939 R 1112912 CDS YP_005154304.1 376280298 11728090 614759..615775 1 NC_016797.1 identified by match to protein family HMM PF00892; hypothetical protein 615775 11728090 BSVBI22_A0614 Brucella suis VBI22 hypothetical protein YP_005154304.1 614759 D 1112912 CDS YP_005154305.1 376280299 11728091 complement(615780..617036) 1 NC_016797.1 identified by match to protein family HMM PF00083; major facilitator family transporter 617036 11728091 BSVBI22_A0615 Brucella suis VBI22 major facilitator family transporter YP_005154305.1 615780 R 1112912 CDS YP_005154306.1 376280300 11728092 complement(617198..618070) 1 NC_016797.1 identified by match to protein family HMM PF03167; match to protein family HMM TIGR00758; phage SPO1 DNA polymerase-related protein 618070 11728092 BSVBI22_A0616 Brucella suis VBI22 phage SPO1 DNA polymerase-related protein YP_005154306.1 617198 R 1112912 CDS YP_005154307.1 376280301 11728093 618459..620150 1 NC_016797.1 identified by similarity to EGAD:4120; match to protein family HMM PF05187; electron transfer flavoprotein-ubiquinone oxidoreductase 620150 11728093 BSVBI22_A0617 Brucella suis VBI22 electron transfer flavoprotein-ubiquinone oxidoreductase YP_005154307.1 618459 D 1112912 CDS YP_005154308.1 376280302 11728094 complement(620266..621234) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6082; match to protein family HMM PF03372; AP endonuclease domain-containing protein 621234 11728094 BSVBI22_A0618 Brucella suis VBI22 AP endonuclease domain-containing protein YP_005154308.1 620266 R 1112912 CDS YP_005154309.1 376280303 11728095 complement(621395..622897) 1 NC_016797.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 622897 amn 11728095 amn Brucella suis VBI22 AMP nucleosidase YP_005154309.1 621395 R 1112912 CDS YP_005154310.1 376280304 11728096 622950..623108 1 NC_016797.1 hypothetical protein 623108 11728096 BSVBI22_A0620 Brucella suis VBI22 hypothetical protein YP_005154310.1 622950 D 1112912 CDS YP_005154311.1 376280305 11728097 623090..623386 1 NC_016797.1 hypothetical protein 623386 11728097 BSVBI22_A0621 Brucella suis VBI22 hypothetical protein YP_005154311.1 623090 D 1112912 CDS YP_005154312.1 376280306 11728098 623464..624174 1 NC_016797.1 identified by similarity to OMNI:CC2434; match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase family protein 624174 11728098 BSVBI22_A0622 Brucella suis VBI22 glutathione S-transferase family protein YP_005154312.1 623464 D 1112912 CDS YP_005154313.1 376280307 11728099 complement(624233..624580) 1 NC_016797.1 identified by similarity to GP:15073978; hypothetical protein 624580 11728099 BSVBI22_A0623 Brucella suis VBI22 hypothetical protein YP_005154313.1 624233 R 1112912 CDS YP_005154314.1 376280308 11728100 complement(624577..624867) 1 NC_016797.1 hypothetical protein 624867 11728100 BSVBI22_A0624 Brucella suis VBI22 hypothetical protein YP_005154314.1 624577 R 1112912 CDS YP_005154315.1 376280309 11728101 625086..625343 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6087; hypothetical protein 625343 11728101 BSVBI22_A0625 Brucella suis VBI22 hypothetical protein YP_005154315.1 625086 D 1112912 CDS YP_005154316.1 376280310 11728102 complement(625403..626176) 1 NC_016797.1 identified by similarity to OMNI:VC0940; match to protein family HMM PF02588; hypothetical protein 626176 11728102 BSVBI22_A0626 Brucella suis VBI22 hypothetical protein YP_005154316.1 625403 R 1112912 CDS YP_005154317.1 376280311 11728103 626168..626281 1 NC_016797.1 hypothetical protein 626281 11728103 BSVBI22_A0627 Brucella suis VBI22 hypothetical protein YP_005154317.1 626168 D 1112912 CDS YP_005154318.1 376280312 11728104 626440..626535 1 NC_016797.1 hypothetical protein 626535 11728104 BSVBI22_A0628 Brucella suis VBI22 hypothetical protein YP_005154318.1 626440 D 1112912 CDS YP_005154319.1 376280313 11728105 626829..627479 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2997; hypothetical protein 627479 11728105 BSVBI22_A0629 Brucella suis VBI22 hypothetical protein YP_005154319.1 626829 D 1112912 CDS YP_005154320.1 376280314 11728106 complement(627524..627898) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6597; match to protein family HMM PF04241; hypothetical protein 627898 11728106 BSVBI22_A0630 Brucella suis VBI22 hypothetical protein YP_005154320.1 627524 R 1112912 CDS YP_005154321.1 376280315 11728107 complement(627916..629049) 1 NC_016797.1 catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate; histidinol-phosphate aminotransferase 629049 11728107 BSVBI22_A0631 Brucella suis VBI22 histidinol-phosphate aminotransferase YP_005154321.1 627916 R 1112912 CDS YP_005154322.1 376280316 11728108 complement(629412..630338) 1 NC_016797.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; phage integrase family site specific recombinase 630338 11728108 BSVBI22_A0632 Brucella suis VBI22 phage integrase family site specific recombinase YP_005154322.1 629412 R 1112912 CDS YP_005154323.1 376280317 11728109 complement(630612..631715) 1 NC_016797.1 identified by similarity to GP:841493; match to protein family HMM PF02530; porin Omp2a 631715 omp2a 11728109 omp2a Brucella suis VBI22 porin Omp2a YP_005154323.1 630612 R 1112912 CDS YP_005154324.1 376280318 11728111 complement(632369..632476) 1 NC_016797.1 hypothetical protein 632476 11728111 BSVBI22_A0634 Brucella suis VBI22 hypothetical protein YP_005154324.1 632369 R 1112912 CDS YP_005154325.1 376280319 11728112 632516..633643 1 NC_016797.1 identified by similarity to GP:841494; match to protein family HMM PF02530; porin Omp2a 633643 omp2b 11728112 omp2b Brucella suis VBI22 porin Omp2a YP_005154325.1 632516 D 1112912 CDS YP_005154326.1 376280320 11728113 633787..634428 1 NC_016797.1 hypothetical protein 634428 11728113 BSVBI22_A0636 Brucella suis VBI22 hypothetical protein YP_005154326.1 633787 D 1112912 CDS YP_005154327.1 376280321 11728114 complement(634478..634678) 1 NC_016797.1 hypothetical protein 634678 11728114 BSVBI22_A0637 Brucella suis VBI22 hypothetical protein YP_005154327.1 634478 R 1112912 CDS YP_005154328.1 376280322 11728115 634728..635402 1 NC_016797.1 identified by similarity to EGAD:126787; hypothetical protein 635402 11728115 BSVBI22_A0638 Brucella suis VBI22 hypothetical protein YP_005154328.1 634728 D 1112912 CDS YP_005154329.1 376280323 11728116 complement(635465..637423) 1 NC_016797.1 identified by match to protein family HMM PF01464; transglycosylase 637423 11728116 BSVBI22_A0639 Brucella suis VBI22 transglycosylase YP_005154329.1 635465 R 1112912 CDS YP_005154330.1 376280324 11728117 637446..637610 1 NC_016797.1 hypothetical protein 637610 11728117 BSVBI22_A0640 Brucella suis VBI22 hypothetical protein YP_005154330.1 637446 D 1112912 CDS YP_005154331.1 376280325 11728118 637693..637785 1 NC_016797.1 hypothetical protein 637785 11728118 BSVBI22_A0641 Brucella suis VBI22 hypothetical protein YP_005154331.1 637693 D 1112912 CDS YP_005154332.1 376280326 11728119 637998..638879 1 NC_016797.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 638879 dapA 11728119 dapA Brucella suis VBI22 dihydrodipicolinate synthase YP_005154332.1 637998 D 1112912 CDS YP_005154333.1 376280327 11728120 638970..639446 1 NC_016797.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 639446 smpB 11728120 smpB Brucella suis VBI22 SsrA-binding protein YP_005154333.1 638970 D 1112912 CDS YP_005154334.1 376280328 11728121 complement(639682..640353) 1 NC_016797.1 identified by match to protein family HMM PF03167; phage SPO1 DNA polymerase-related protein 640353 11728121 BSVBI22_A0644 Brucella suis VBI22 phage SPO1 DNA polymerase-related protein YP_005154334.1 639682 R 1112912 CDS YP_005154335.1 376280329 11728122 complement(640384..640959) 1 NC_016797.1 identified by match to protein family HMM PF01936; hypothetical protein 640959 11728122 BSVBI22_A0645 Brucella suis VBI22 hypothetical protein YP_005154335.1 640384 R 1112912 CDS YP_005154336.1 376280330 11728123 complement(641159..641314) 1 NC_016797.1 hypothetical protein 641314 11728123 BSVBI22_A0646 Brucella suis VBI22 hypothetical protein YP_005154336.1 641159 R 1112912 CDS YP_005154337.1 376280331 11728124 641356..641757 1 NC_016797.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 641757 rpoZ 11728124 rpoZ Brucella suis VBI22 DNA-directed RNA polymerase subunit omega YP_005154337.1 641356 D 1112912 CDS YP_005154338.1 376280332 11728125 641998..644250 1 NC_016797.1 identified by match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; RelA/SpoT family protein 644250 11728125 BSVBI22_A0648 Brucella suis VBI22 RelA/SpoT family protein YP_005154338.1 641998 D 1112912 CDS YP_005154339.1 376280333 11728126 644258..644836 1 NC_016797.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 644836 pyrE 11728126 pyrE Brucella suis VBI22 orotate phosphoribosyltransferase YP_005154339.1 644258 D 1112912 CDS YP_005154340.1 376280334 11728127 645005..645751 1 NC_016797.1 identified by match to protein family HMM PF00027; match to protein family HMM PF00325; Crp/FNR family transcriptional regulator 645751 11728127 BSVBI22_A0650 Brucella suis VBI22 Crp/FNR family transcriptional regulator YP_005154340.1 645005 D 1112912 CDS YP_005154341.1 376280335 11728128 646132..647466 1 NC_016797.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 647466 hemN-1 11728128 hemN-1 Brucella suis VBI22 coproporphyrinogen III oxidase YP_005154341.1 646132 D 1112912 CDS YP_005154342.1 376280336 11728129 complement(647650..648861) 1 NC_016797.1 identified by similarity to EGAD:36955; fosmidomycin resistance protein 648861 fsr 11728129 fsr Brucella suis VBI22 fosmidomycin resistance protein YP_005154342.1 647650 R 1112912 CDS YP_005154343.1 376280337 11728130 649113..649895 1 NC_016797.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; AraC family transcriptional regulator 649895 11728130 BSVBI22_A0653 Brucella suis VBI22 AraC family transcriptional regulator YP_005154343.1 649113 D 1112912 CDS YP_005154344.1 376280338 11728131 649948..650520 1 NC_016797.1 identified by similarity to GP:14027200; hypothetical protein 650520 11728131 BSVBI22_A0654 Brucella suis VBI22 hypothetical protein YP_005154344.1 649948 D 1112912 CDS YP_005154345.1 376280339 11728132 650517..650921 1 NC_016797.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 650921 acpS 11728132 acpS Brucella suis VBI22 4'-phosphopantetheinyl transferase YP_005154345.1 650517 D 1112912 CDS YP_005154346.1 376280340 11728133 651032..651814 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6121; match to protein family HMM PF00461; signal peptidase I 651814 11728133 BSVBI22_A0656 Brucella suis VBI22 signal peptidase I YP_005154346.1 651032 D 1112912 CDS YP_005154347.1 376280341 11728134 651783..652520 1 NC_016797.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 652520 rncS 11728134 rncS Brucella suis VBI22 ribonuclease III YP_005154347.1 651783 D 1112912 CDS YP_005154348.1 376280342 11728135 652563..652661 1 NC_016797.1 hypothetical protein 652661 11728135 BSVBI22_A0658 Brucella suis VBI22 hypothetical protein YP_005154348.1 652563 D 1112912 CDS YP_005154349.1 376280343 11728136 652665..653600 1 NC_016797.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 653600 era 11728136 era Brucella suis VBI22 GTP-binding protein Era YP_005154349.1 652665 D 1112912 CDS YP_005154350.1 376280344 11728137 653627..654370 1 NC_016797.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 654370 recO 11728137 recO Brucella suis VBI22 DNA repair protein RecO YP_005154350.1 653627 D 1112912 CDS YP_005154351.1 376280345 11728138 complement(654348..654857) 1 NC_016797.1 identified by similarity to GP:15074034; hypothetical protein 654857 11728138 BSVBI22_A0661 Brucella suis VBI22 hypothetical protein YP_005154351.1 654348 R 1112912 CDS YP_005154352.1 376280346 11728139 complement(654854..655474) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6141; hypothetical protein 655474 11728139 BSVBI22_A0662 Brucella suis VBI22 hypothetical protein YP_005154352.1 654854 R 1112912 CDS YP_005154353.1 376280347 11728140 complement(655474..656337) 1 NC_016797.1 identified by match to protein family HMM PF01571; aminomethyltransferase 656337 11728140 BSVBI22_A0663 Brucella suis VBI22 aminomethyltransferase YP_005154353.1 655474 R 1112912 CDS YP_005154354.1 376280348 11728141 656423..657757 1 NC_016797.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 657757 pyrC-1 11728141 pyrC-1 Brucella suis VBI22 dihydroorotase YP_005154354.1 656423 D 1112912 CDS YP_005154355.1 376280349 11728142 complement(657806..658570) 1 NC_016797.1 identified by similarity to GP:14027225; hypothetical protein 658570 11728142 BSVBI22_A0665 Brucella suis VBI22 hypothetical protein YP_005154355.1 657806 R 1112912 CDS YP_005154356.1 376280350 11728143 complement(658619..658885) 1 NC_016797.1 identified by similarity to GP:15074038; hypothetical protein 658885 11728143 BSVBI22_A0666 Brucella suis VBI22 hypothetical protein YP_005154356.1 658619 R 1112912 CDS YP_005154357.1 376280351 11728144 complement(659042..659425) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6146; hypothetical protein 659425 11728144 BSVBI22_A0667 Brucella suis VBI22 hypothetical protein YP_005154357.1 659042 R 1112912 CDS YP_005154358.1 376280352 11728145 complement(659505..659948) 1 NC_016797.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 659948 11728145 BSVBI22_A0668 Brucella suis VBI22 MutT/nudix family protein YP_005154358.1 659505 R 1112912 CDS YP_005154359.1 376280353 11728146 660034..660813 1 NC_016797.1 identified by similarity to EGAD:107474; match to protein family HMM PF02586; hypothetical protein 660813 11728146 BSVBI22_A0669 Brucella suis VBI22 hypothetical protein YP_005154359.1 660034 D 1112912 CDS YP_005154360.1 376280354 11728147 660868..661482 1 NC_016797.1 identified by match to protein family HMM PF01810; amino acid transporter LysE 661482 11728147 BSVBI22_A0670 Brucella suis VBI22 amino acid transporter LysE YP_005154360.1 660868 D 1112912 CDS YP_005154361.1 376280355 11728148 complement(661459..661626) 1 NC_016797.1 hypothetical protein 661626 11728148 BSVBI22_A0671 Brucella suis VBI22 hypothetical protein YP_005154361.1 661459 R 1112912 CDS YP_005154362.1 376280356 11728149 661752..661874 1 NC_016797.1 hypothetical protein 661874 11728149 BSVBI22_A0672 Brucella suis VBI22 hypothetical protein YP_005154362.1 661752 D 1112912 CDS YP_005154363.1 376280357 11728150 661993..663513 1 NC_016797.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 663513 cysS 11728150 cysS Brucella suis VBI22 cysteinyl-tRNA synthetase YP_005154363.1 661993 D 1112912 CDS YP_005154364.1 376280358 11728151 663532..663666 1 NC_016797.1 hypothetical protein 663666 11728151 BSVBI22_A0674 Brucella suis VBI22 hypothetical protein YP_005154364.1 663532 D 1112912 CDS YP_005154365.1 376280359 11728152 663666..665279 1 NC_016797.1 catalyzes the formation of 2-isopropylmalate from 1-methyl-2-oxobutanoate and acetyl-CoA; putative alpha-isopropylmalate/homocitrate synthase family transferase 665279 11728152 BSVBI22_A0675 Brucella suis VBI22 putative alpha-isopropylmalate/homocitrate synthase family transferase YP_005154365.1 663666 D 1112912 CDS YP_005154366.1 376280360 11728153 665526..666446 1 NC_016797.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688; rarD protein 666446 rarD 11728153 rarD Brucella suis VBI22 rarD protein YP_005154366.1 665526 D 1112912 CDS YP_005154367.1 376280361 11728154 666579..668312 1 NC_016797.1 identified by match to protein family HMM PF01551; M24/M37 family peptidase 668312 11728154 BSVBI22_A0677 Brucella suis VBI22 M24/M37 family peptidase YP_005154367.1 666579 D 1112912 CDS YP_005154368.1 376280362 11728155 complement(668380..669210) 1 NC_016797.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 669210 ksgA 11728155 ksgA Brucella suis VBI22 dimethyladenosine transferase YP_005154368.1 668380 R 1112912 CDS YP_005154369.1 376280363 11728156 complement(669207..670238) 1 NC_016797.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 670238 pdxA 11728156 pdxA Brucella suis VBI22 4-hydroxythreonine-4-phosphate dehydrogenase YP_005154369.1 669207 R 1112912 CDS YP_005154370.1 376280364 11728157 complement(670303..671259) 1 NC_016797.1 peptidyl-prolyl cis-trans isomerase 671259 11728157 BSVBI22_A0680 Brucella suis VBI22 peptidyl-prolyl cis-trans isomerase YP_005154370.1 670303 R 1112912 CDS YP_005154371.1 376280365 11728158 complement(671570..673948) 1 NC_016797.1 identified by similarity to EGAD:7471; match to protein family HMM PF04453; organic solvent tolerance 673948 11728158 BSVBI22_A0681 Brucella suis VBI22 organic solvent tolerance YP_005154371.1 671570 R 1112912 CDS YP_005154372.1 376280366 11728159 complement(673969..675057) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6205; match to protein family HMM PF03739; hypothetical protein 675057 11728159 BSVBI22_A0682 Brucella suis VBI22 hypothetical protein YP_005154372.1 673969 R 1112912 CDS YP_005154373.1 376280367 11728160 complement(675054..676262) 1 NC_016797.1 identified by match to protein family HMM PF03739; hypothetical protein 676262 11728160 BSVBI22_A0683 Brucella suis VBI22 hypothetical protein YP_005154373.1 675054 R 1112912 CDS YP_005154374.1 376280368 11728161 complement(676435..676653) 1 NC_016797.1 hypothetical protein 676653 11728161 BSVBI22_A0684 Brucella suis VBI22 hypothetical protein YP_005154374.1 676435 R 1112912 CDS YP_005154375.1 376280369 11728162 676672..678165 1 NC_016797.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 678165 11728162 BSVBI22_A0685 Brucella suis VBI22 leucyl aminopeptidase YP_005154375.1 676672 D 1112912 CDS YP_005154376.1 376280370 11728163 678237..678686 1 NC_016797.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 678686 11728163 BSVBI22_A0686 Brucella suis VBI22 DNA polymerase III subunit chi YP_005154376.1 678237 D 1112912 CDS YP_005154377.1 376280371 11728164 678686..679249 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6220; hypothetical protein 679249 11728164 BSVBI22_A0687 Brucella suis VBI22 hypothetical protein YP_005154377.1 678686 D 1112912 CDS YP_005154378.1 376280372 11728165 complement(679326..681209) 1 NC_016797.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 681209 11728165 BSVBI22_A0688 Brucella suis VBI22 ABC transporter ATP-binding protein YP_005154378.1 679326 R 1112912 CDS YP_005154379.1 376280373 11728166 complement(681252..681764) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6242; match to protein family HMM PF05163; hypothetical protein 681764 11728166 BSVBI22_A0689 Brucella suis VBI22 hypothetical protein YP_005154379.1 681252 R 1112912 CDS YP_005154380.1 376280374 11728167 681993..682415 1 NC_016797.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 682415 ndk 11728167 ndk Brucella suis VBI22 nucleoside diphosphate kinase YP_005154380.1 681993 D 1112912 CDS YP_005154381.1 376280375 11728168 complement(682524..683327) 1 NC_016797.1 identified by similarity to GP:14027320; match to protein family HMM PF03724; hypothetical protein 683327 11728168 BSVBI22_A0691 Brucella suis VBI22 hypothetical protein YP_005154381.1 682524 R 1112912 CDS YP_005154382.1 376280376 11728169 complement(683563..684054) 1 NC_016797.1 identified by similarity to SP:P30749; match to protein family HMM PF02391; molybdopterin converting factor subunit 2 684054 moaE 11728169 moaE Brucella suis VBI22 molybdopterin converting factor subunit 2 YP_005154382.1 683563 R 1112912 CDS YP_005154383.1 376280377 11728170 complement(684056..684313) 1 NC_016797.1 identified by match to protein family HMM PF02597; match to protein family HMM TIGR01682; molybdopterin converting factor subunit 1 684313 moaD 11728170 moaD Brucella suis VBI22 molybdopterin converting factor subunit 1 YP_005154383.1 684056 R 1112912 CDS YP_005154384.1 376280378 11728171 complement(684318..684902) 1 NC_016797.1 identified by similarity to SP:P06978; match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 684902 pgsA 11728171 pgsA Brucella suis VBI22 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_005154384.1 684318 R 1112912 CDS YP_005154385.1 376280379 11728172 complement(685021..687093) 1 NC_016797.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal is responsible for the 3' incision and the C-terminal is responsible for the 5' incision; excinuclease ABC subunit C 687093 uvrC 11728172 uvrC Brucella suis VBI22 excinuclease ABC subunit C YP_005154385.1 685021 R 1112912 CDS YP_005154386.1 376280380 11728173 complement(687093..687848) 1 NC_016797.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 687848 11728173 BSVBI22_A0696 Brucella suis VBI22 short chain dehydrogenase YP_005154386.1 687093 R 1112912 CDS YP_005154387.1 376280381 11728174 688250..688891 1 NC_016797.1 identified by similarity to SP:Q45689; match to protein family HMM PF01389; outer-membrane protein Omp25 688891 omp25 11728174 omp25 Brucella suis VBI22 outer-membrane protein Omp25 YP_005154387.1 688250 D 1112912 CDS YP_005154388.1 376280382 11728175 complement(688988..689587) 1 NC_016797.1 identified by similarity to OMNI:CC0147; match to protein family HMM PF02798; glutathione S-transferase family protein 689587 11728175 BSVBI22_A0698 Brucella suis VBI22 glutathione S-transferase family protein YP_005154388.1 688988 R 1112912 CDS YP_005154389.1 376280383 11728176 complement(689642..690331) 1 NC_016797.1 identified by match to protein family HMM PF00445; ribonuclease T2 family protein 690331 11728176 BSVBI22_A0699 Brucella suis VBI22 ribonuclease T2 family protein YP_005154389.1 689642 R 1112912 CDS YP_005154390.1 376280384 11728177 complement(690344..690814) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6225; hypothetical protein 690814 11728177 BSVBI22_A0700 Brucella suis VBI22 hypothetical protein YP_005154390.1 690344 R 1112912 CDS YP_005154391.1 376280385 11728178 complement(690897..691769) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6221; match to protein family HMM PF04378; hypothetical protein 691769 11728178 BSVBI22_A0701 Brucella suis VBI22 hypothetical protein YP_005154391.1 690897 R 1112912 CDS YP_005154392.1 376280386 11728179 691925..692770 1 NC_016797.1 identified by similarity to GP:15074178; match to protein family HMM PF00892; hypothetical protein 692770 11728179 BSVBI22_A0702 Brucella suis VBI22 hypothetical protein YP_005154392.1 691925 D 1112912 CDS YP_005154393.1 376280387 11728180 692848..694974 1 NC_016797.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; oxidoreductase, molybdopterin-binding 694974 11728180 BSVBI22_A0703 Brucella suis VBI22 oxidoreductase, molybdopterin-binding YP_005154393.1 692848 D 1112912 CDS YP_005154394.1 376280388 11728181 complement(695201..695725) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2404; hypothetical protein 695725 11728181 BSVBI22_A0704 Brucella suis VBI22 hypothetical protein YP_005154394.1 695201 R 1112912 CDS YP_005154395.1 376280389 11728182 complement(695901..696518) 1 NC_016797.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 696518 purN 11728182 purN Brucella suis VBI22 phosphoribosylglycinamide formyltransferase YP_005154395.1 695901 R 1112912 CDS YP_005154396.1 376280390 11728183 complement(696515..697594) 1 NC_016797.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 697594 purM 11728183 purM Brucella suis VBI22 phosphoribosylaminoimidazole synthetase YP_005154396.1 696515 R 1112912 CDS YP_005154397.1 376280391 11728184 complement(697636..697815) 1 NC_016797.1 hypothetical protein 697815 11728184 BSVBI22_A0707 Brucella suis VBI22 hypothetical protein YP_005154397.1 697636 R 1112912 CDS YP_005154398.1 376280392 11728185 complement(697943..698044) 1 NC_016797.1 hypothetical protein 698044 11728185 BSVBI22_A0708 Brucella suis VBI22 hypothetical protein YP_005154398.1 697943 R 1112912 CDS YP_005154399.1 376280393 11728186 698084..699232 1 NC_016797.1 identified by match to protein family HMM PF01594; permease 699232 11728186 BSVBI22_A0709 Brucella suis VBI22 permease YP_005154399.1 698084 D 1112912 CDS YP_005154400.1 376280394 11728187 699272..699967 1 NC_016797.1 identified by similarity to GP:14027358; hypothetical protein 699967 11728187 BSVBI22_A0710 Brucella suis VBI22 hypothetical protein YP_005154400.1 699272 D 1112912 CDS YP_005154401.1 376280395 11728188 699964..700833 1 NC_016797.1 epimerase/dehydratase family protein 700833 11728188 BSVBI22_A0711 Brucella suis VBI22 epimerase/dehydratase family protein YP_005154401.1 699964 D 1112912 CDS YP_005154402.1 376280396 11728189 complement(700830..701615) 1 NC_016797.1 hypothetical protein 701615 11728189 BSVBI22_A0712 Brucella suis VBI22 hypothetical protein YP_005154402.1 700830 R 1112912 CDS YP_005154403.1 376280397 11728190 complement(701688..702392) 1 NC_016797.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 702392 11728190 BSVBI22_A0713 Brucella suis VBI22 short chain dehydrogenase/reductase family oxidoreductase YP_005154403.1 701688 R 1112912 CDS YP_005154404.1 376280398 11728191 complement(702554..702769) 1 NC_016797.1 hypothetical protein 702769 11728191 BSVBI22_A0714 Brucella suis VBI22 hypothetical protein YP_005154404.1 702554 R 1112912 CDS YP_005154405.1 376280399 11728192 702783..702938 1 NC_016797.1 hypothetical protein 702938 11728192 BSVBI22_A0715 Brucella suis VBI22 hypothetical protein YP_005154405.1 702783 D 1112912 CDS YP_005154406.1 376280400 11728193 complement(703091..704764) 1 NC_016797.1 identified by similarity to SP:P33231; match to protein family HMM PF02652; match to protein family HMM TIGR00795; L-lactate permease 704764 lldP 11728193 lldP Brucella suis VBI22 L-lactate permease YP_005154406.1 703091 R 1112912 CDS YP_005154407.1 376280401 11728195 705298..705603 1 NC_016797.1 identified by similarity to GP:15074650; match to protein family HMM PF04800; oxidoreductase 705603 11728195 BSVBI22_A0717 Brucella suis VBI22 oxidoreductase YP_005154407.1 705298 D 1112912 CDS YP_005154408.1 376280402 11728197 706169..706759 1 NC_016797.1 hypothetical protein 706759 11728197 BSVBI22_A0718 Brucella suis VBI22 hypothetical protein YP_005154408.1 706169 D 1112912 CDS YP_005154409.1 376280403 11728198 complement(706980..707591) 1 NC_016797.1 identified by match to protein family HMM PF00929; exonuclease 707591 11728198 BSVBI22_A0719 Brucella suis VBI22 exonuclease YP_005154409.1 706980 R 1112912 CDS YP_005154410.1 376280404 11728199 complement(707916..708434) 1 NC_016797.1 identified by similarity to EGAD:40466; adenylate kinase 708434 11728199 BSVBI22_A0720 Brucella suis VBI22 adenylate kinase YP_005154410.1 707916 R 1112912 CDS YP_005154411.1 376280405 11728200 complement(708458..709993) 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 709993 11728200 BSVBI22_A0721 Brucella suis VBI22 acetyltransferase YP_005154411.1 708458 R 1112912 CDS YP_005154412.1 376280406 11728201 complement(709968..710762) 1 NC_016797.1 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 710762 11728201 BSVBI22_A0722 Brucella suis VBI22 Cro/CI family transcriptional regulator YP_005154412.1 709968 R 1112912 CDS YP_005154413.1 376280407 11728202 complement(710787..711206) 1 NC_016797.1 hypothetical protein 711206 11728202 BSVBI22_A0723 Brucella suis VBI22 hypothetical protein YP_005154413.1 710787 R 1112912 CDS YP_005154414.1 376280408 11728203 711586..712482 1 NC_016797.1 hypothetical protein 712482 11728203 BSVBI22_A0724 Brucella suis VBI22 hypothetical protein YP_005154414.1 711586 D 1112912 CDS YP_005154415.1 376280409 11728204 712482..714596 1 NC_016797.1 identified by match to protein family HMM PF00665; transposase 714596 11728204 BSVBI22_A0725 Brucella suis VBI22 transposase YP_005154415.1 712482 D 1112912 CDS YP_005154416.1 376280410 11728205 714589..715539 1 NC_016797.1 identified by similarity to GP:11071899; transposition protein 715539 11728205 BSVBI22_A0726 Brucella suis VBI22 transposition protein YP_005154416.1 714589 D 1112912 CDS YP_005154417.1 376280411 11728206 715536..717113 1 NC_016797.1 hypothetical protein 717113 11728206 BSVBI22_A0727 Brucella suis VBI22 hypothetical protein YP_005154417.1 715536 D 1112912 CDS YP_005154418.1 376280412 11728207 complement(717412..717609) 1 NC_016797.1 hypothetical protein 717609 11728207 BSVBI22_A0728 Brucella suis VBI22 hypothetical protein YP_005154418.1 717412 R 1112912 CDS YP_005154419.1 376280413 11728208 717850..719157 1 NC_016797.1 hypothetical protein 719157 11728208 BSVBI22_A0729 Brucella suis VBI22 hypothetical protein YP_005154419.1 717850 D 1112912 CDS YP_005154420.1 376280414 11728209 719611..720984 1 NC_016797.1 hypothetical protein 720984 11728209 BSVBI22_A0730 Brucella suis VBI22 hypothetical protein YP_005154420.1 719611 D 1112912 CDS YP_005154421.1 376280415 11728210 721118..721951 1 NC_016797.1 hypothetical protein 721951 11728210 BSVBI22_A0731 Brucella suis VBI22 hypothetical protein YP_005154421.1 721118 D 1112912 CDS YP_005154422.1 376280416 11728211 complement(722335..722847) 1 NC_016797.1 identified by similarity to GP:15162152; hypothetical protein 722847 11728211 BSVBI22_A0732 Brucella suis VBI22 hypothetical protein YP_005154422.1 722335 R 1112912 CDS YP_005154423.1 376280417 11728212 complement(723007..723255) 1 NC_016797.1 putative lipoprotein 723255 11728212 BSVBI22_A0733 Brucella suis VBI22 putative lipoprotein YP_005154423.1 723007 R 1112912 CDS YP_005154424.1 376280418 11728213 complement(723358..723513) 1 NC_016797.1 hypothetical protein 723513 11728213 BSVBI22_A0734 Brucella suis VBI22 hypothetical protein YP_005154424.1 723358 R 1112912 CDS YP_005154425.1 376280419 11728214 complement(723500..724669) 1 NC_016797.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 724669 metC 11728214 metC Brucella suis VBI22 cystathionine beta-lyase YP_005154425.1 723500 R 1112912 CDS YP_005154426.1 376280420 11728215 724880..725647 1 NC_016797.1 identified by match to protein family HMM PF01569; PAP2 family protein 725647 11728215 BSVBI22_A0736 Brucella suis VBI22 PAP2 family protein YP_005154426.1 724880 D 1112912 CDS YP_005154427.1 376280421 11728216 726103..727134 1 NC_016797.1 identified by similarity to EGAD:35379; match to protein family HMM PF00497; match to protein family HMM TIGR01096; amino acid ABC transporter substrate-binding protein 727134 11728216 BSVBI22_A0737 Brucella suis VBI22 amino acid ABC transporter substrate-binding protein YP_005154427.1 726103 D 1112912 CDS YP_005154428.1 376280422 11728217 727168..727395 1 NC_016797.1 hypothetical protein 727395 11728217 BSVBI22_A0738 Brucella suis VBI22 hypothetical protein YP_005154428.1 727168 D 1112912 CDS YP_005154429.1 376280423 11728218 727431..728624 1 NC_016797.1 identified by similarity to EGAD:35466; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 728624 11728218 BSVBI22_A0739 Brucella suis VBI22 amino acid ABC transporter permease YP_005154429.1 727431 D 1112912 CDS YP_005154430.1 376280424 11728219 728627..729784 1 NC_016797.1 identified by similarity to SP:P45768; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 729784 11728219 BSVBI22_A0740 Brucella suis VBI22 amino acid ABC transporter permease YP_005154430.1 728627 D 1112912 CDS YP_005154431.1 376280425 11728220 729865..730614 1 NC_016797.1 identified by similarity to EGAD:31037; match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 730614 11728220 BSVBI22_A0741 Brucella suis VBI22 amino acid ABC transporter ATP-binding protein YP_005154431.1 729865 D 1112912 CDS YP_005154432.1 376280426 11728221 complement(730662..731867) 1 NC_016797.1 catalyzes the formation of catechol from salicylate; salicylate hydroxylase 731867 11728221 BSVBI22_A0742 Brucella suis VBI22 salicylate hydroxylase YP_005154432.1 730662 R 1112912 CDS YP_005154433.1 376280427 11728222 complement(731897..732151) 1 NC_016797.1 identified by similarity to GP:15074414; hypothetical protein 732151 11728222 BSVBI22_A0743 Brucella suis VBI22 hypothetical protein YP_005154433.1 731897 R 1112912 CDS YP_005154434.1 376280428 11728223 732437..734677 1 NC_016797.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 734677 ppk 11728223 ppk Brucella suis VBI22 polyphosphate kinase YP_005154434.1 732437 D 1112912 CDS YP_005154435.1 376280429 11728224 734674..736212 1 NC_016797.1 identified by match to protein family HMM PF02541; Ppx/GppA family phosphatase 736212 11728224 BSVBI22_A0745 Brucella suis VBI22 Ppx/GppA family phosphatase YP_005154435.1 734674 D 1112912 CDS YP_005154436.1 376280430 11728225 complement(736358..737515) 1 NC_016797.1 identified by similarity to GP:17739552; match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388; ribonuclease D 737515 rnd 11728225 rnd Brucella suis VBI22 ribonuclease D YP_005154436.1 736358 R 1112912 CDS YP_005154437.1 376280431 11728226 737742..739529 1 NC_016797.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 739529 aspS 11728226 aspS Brucella suis VBI22 aspartyl-tRNA synthetase YP_005154437.1 737742 D 1112912 CDS YP_005154438.1 376280432 11728227 complement(739613..740809) 1 NC_016797.1 identified by similarity to GP:14027664; hypothetical protein 740809 11728227 BSVBI22_A0748 Brucella suis VBI22 hypothetical protein YP_005154438.1 739613 R 1112912 CDS YP_005154439.1 376280433 11728228 740864..741103 1 NC_016797.1 hypothetical protein 741103 11728228 BSVBI22_A0749 Brucella suis VBI22 hypothetical protein YP_005154439.1 740864 D 1112912 CDS YP_005154440.1 376280434 11728229 741209..743521 1 NC_016797.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 743521 parC 11728229 parC Brucella suis VBI22 DNA topoisomerase IV subunit A YP_005154440.1 741209 D 1112912 CDS YP_005154441.1 376280435 11728230 complement(743700..744449) 1 NC_016797.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase 744449 11728230 BSVBI22_A0751 Brucella suis VBI22 arginyl-tRNA-protein transferase YP_005154441.1 743700 R 1112912 CDS YP_005154442.1 376280436 11728231 complement(744570..745040) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6587; hypothetical protein 745040 11728231 BSVBI22_A0752 Brucella suis VBI22 hypothetical protein YP_005154442.1 744570 R 1112912 CDS YP_005154443.1 376280437 11728232 complement(745187..746224) 1 NC_016797.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 746224 hemB 11728232 hemB Brucella suis VBI22 delta-aminolevulinic acid dehydratase YP_005154443.1 745187 R 1112912 CDS YP_005154444.1 376280438 11728233 746392..747441 1 NC_016797.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 747441 11728233 BSVBI22_A0754 Brucella suis VBI22 enoyl-CoA hydratase YP_005154444.1 746392 D 1112912 CDS YP_005154445.1 376280439 11728234 747455..747889 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6608; hypothetical protein 747889 11728234 BSVBI22_A0755 Brucella suis VBI22 hypothetical protein YP_005154445.1 747455 D 1112912 CDS YP_005154446.1 376280440 11728235 748120..748719 1 NC_016797.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 748719 11728235 BSVBI22_A0756 Brucella suis VBI22 MarR family transcriptional regulator YP_005154446.1 748120 D 1112912 CDS YP_005154447.1 376280441 11728236 complement(748806..748946) 1 NC_016797.1 hypothetical protein 748946 11728236 BSVBI22_A0757 Brucella suis VBI22 hypothetical protein YP_005154447.1 748806 R 1112912 CDS YP_005154448.1 376280442 11728237 749081..750382 1 NC_016797.1 identified by match to protein family HMM PF01471; match to protein family HMM TIGR01409; peptidoglycan-binding protein 750382 11728237 BSVBI22_A0758 Brucella suis VBI22 peptidoglycan-binding protein YP_005154448.1 749081 D 1112912 CDS YP_005154449.1 376280443 11728238 complement(750388..750483) 1 NC_016797.1 hypothetical protein 750483 11728238 BSVBI22_A0759 Brucella suis VBI22 hypothetical protein YP_005154449.1 750388 R 1112912 CDS YP_005154450.1 376280444 11728239 750475..750609 1 NC_016797.1 hypothetical protein 750609 11728239 BSVBI22_A0760 Brucella suis VBI22 hypothetical protein YP_005154450.1 750475 D 1112912 CDS YP_005154451.1 376280445 11728240 750613..751929 1 NC_016797.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 751929 glyA 11728240 glyA Brucella suis VBI22 serine hydroxymethyltransferase YP_005154451.1 750613 D 1112912 CDS YP_005154452.1 376280446 11728241 752171..752647 1 NC_016797.1 identified by similarity to GP:14027700; match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 752647 nrdR 11728241 nrdR Brucella suis VBI22 transcriptional regulator NrdR YP_005154452.1 752171 D 1112912 CDS YP_005154453.1 376280447 11728242 752649..753770 1 NC_016797.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00326; riboflavin biosynthesis protein RibD 753770 ribD 11728242 ribD Brucella suis VBI22 riboflavin biosynthesis protein RibD YP_005154453.1 752649 D 1112912 CDS YP_005154454.1 376280448 11728243 753770..754378 1 NC_016797.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 754378 ribE 11728243 ribE Brucella suis VBI22 riboflavin synthase subunit alpha YP_005154454.1 753770 D 1112912 CDS YP_005154455.1 376280449 11728244 754461..754934 1 NC_016797.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 754934 ribH 11728244 ribH Brucella suis VBI22 6,7-dimethyl-8-ribityllumazine synthase YP_005154455.1 754461 D 1112912 CDS YP_005154456.1 376280450 11728245 754940..755455 1 NC_016797.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 755455 nusB 11728245 nusB Brucella suis VBI22 transcription antitermination protein NusB YP_005154456.1 754940 D 1112912 CDS YP_005154457.1 376280451 11728246 755906..758062 1 NC_016797.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 758062 hppA 11728246 hppA Brucella suis VBI22 membrane-bound proton-translocating pyrophosphatase YP_005154457.1 755906 D 1112912 CDS YP_005154458.1 376280452 11728247 complement(758134..758652) 1 NC_016797.1 identified by similarity to GP:15074151; match to protein family HMM PF04355; hypothetical protein 758652 11728247 BSVBI22_A0768 Brucella suis VBI22 hypothetical protein YP_005154458.1 758134 R 1112912 CDS YP_005154459.1 376280453 11728248 758742..759296 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6629; match to protein family HMM PF03981; hypothetical protein 759296 11728248 BSVBI22_A0769 Brucella suis VBI22 hypothetical protein YP_005154459.1 758742 D 1112912 CDS YP_005154460.1 376280454 11728249 759416..759973 1 NC_016797.1 identified by similarity to GP:15074153; hypothetical protein 759973 11728249 BSVBI22_A0770 Brucella suis VBI22 hypothetical protein YP_005154460.1 759416 D 1112912 CDS YP_005154461.1 376280455 11728250 complement(760021..760116) 1 NC_016797.1 hypothetical protein 760116 11728250 BSVBI22_A0771 Brucella suis VBI22 hypothetical protein YP_005154461.1 760021 R 1112912 CDS YP_005154462.1 376280456 11728251 760091..761131 1 NC_016797.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 761131 plsX 11728251 plsX Brucella suis VBI22 putative glycerol-3-phosphate acyltransferase PlsX YP_005154462.1 760091 D 1112912 CDS YP_005154463.1 376280457 11728252 761379..762350 1 NC_016797.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 762350 fabH 11728252 fabH Brucella suis VBI22 3-oxoacyl-ACP synthase YP_005154463.1 761379 D 1112912 CDS YP_005154464.1 376280458 11728253 762469..762792 1 NC_016797.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 762792 ihfA 11728253 ihfA Brucella suis VBI22 integration host factor subunit alpha YP_005154464.1 762469 D 1112912 CDS YP_005154465.1 376280459 11728254 763326..763868 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6634; hypothetical protein 763868 11728254 BSVBI22_A0775 Brucella suis VBI22 hypothetical protein YP_005154465.1 763326 D 1112912 CDS YP_005154466.1 376280460 11728255 complement(763918..764235) 1 NC_016797.1 identified by similarity to SP:P30743; match to protein family HMM PF00893; sugE protein 764235 sugE 11728255 sugE Brucella suis VBI22 sugE protein YP_005154466.1 763918 R 1112912 CDS YP_005154467.1 376280461 11728257 complement(764582..766120) 1 NC_016797.1 identified by match to protein family HMM PF02397; sugar transferase 766120 11728257 BSVBI22_A0777 Brucella suis VBI22 sugar transferase YP_005154467.1 764582 R 1112912 CDS YP_005154468.1 376280462 11728258 complement(766250..766465) 1 NC_016797.1 identified by similarity to GP:14027725; hypothetical protein 766465 11728258 BSVBI22_A0778 Brucella suis VBI22 hypothetical protein YP_005154468.1 766250 R 1112912 CDS YP_005154469.1 376280463 11728259 complement(766474..767061) 1 NC_016797.1 identified by similarity to EGAD:19692; match to protein family HMM PF02563; capsule polysaccharide export protein 767061 11728259 BSVBI22_A0779 Brucella suis VBI22 capsule polysaccharide export protein YP_005154469.1 766474 R 1112912 CDS YP_005154470.1 376280464 11728260 767044..767142 1 NC_016797.1 hypothetical protein 767142 11728260 BSVBI22_A0780 Brucella suis VBI22 hypothetical protein YP_005154470.1 767044 D 1112912 CDS YP_005154471.1 376280465 11728261 767185..767847 1 NC_016797.1 hypothetical protein 767847 11728261 BSVBI22_A0781 Brucella suis VBI22 hypothetical protein YP_005154471.1 767185 D 1112912 CDS YP_005154472.1 376280466 11728262 complement(767915..768133) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6654; hypothetical protein 768133 11728262 BSVBI22_A0782 Brucella suis VBI22 hypothetical protein YP_005154472.1 767915 R 1112912 CDS YP_005154473.1 376280467 11728263 768485..769561 1 NC_016797.1 identified by match to protein family HMM PF02628; cytochrome c oxidase assembly protein 769561 11728263 BSVBI22_A0783 Brucella suis VBI22 cytochrome c oxidase assembly protein YP_005154473.1 768485 D 1112912 CDS YP_005154474.1 376280468 11728264 complement(769714..770646) 1 NC_016797.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase 770646 argC 11728264 argC Brucella suis VBI22 N-acetyl-gamma-glutamyl-phosphate reductase YP_005154474.1 769714 R 1112912 CDS YP_005154475.1 376280469 11728265 complement(770736..771686) 1 NC_016797.1 catalyzes the formation of putrescine from agmatine; agmatinase 771686 11728265 BSVBI22_A0785 Brucella suis VBI22 agmatinase YP_005154475.1 770736 R 1112912 CDS YP_005154476.1 376280470 11728266 complement(771777..772253) 1 NC_016797.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 772253 rpsI 11728266 rpsI Brucella suis VBI22 30S ribosomal protein S9 YP_005154476.1 771777 R 1112912 CDS YP_005154477.1 376280471 11728267 complement(772256..772720) 1 NC_016797.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 772720 rplM 11728267 rplM Brucella suis VBI22 50S ribosomal protein L13 YP_005154477.1 772256 R 1112912 CDS YP_005154478.1 376280472 11728268 complement(772956..773402) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6663; match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 773402 11728268 BSVBI22_A0788 Brucella suis VBI22 hypothetical protein YP_005154478.1 772956 R 1112912 CDS YP_005154479.1 376280473 11728269 773636..774919 1 NC_016797.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 774919 11728269 BSVBI22_A0789 Brucella suis VBI22 O-acetylhomoserine aminocarboxypropyltransferase YP_005154479.1 773636 D 1112912 CDS YP_005154480.1 376280474 11728270 complement(774782..775444) 1 NC_016797.1 hypothetical protein 775444 11728270 BSVBI22_A0790 Brucella suis VBI22 hypothetical protein YP_005154480.1 774782 R 1112912 CDS YP_005154481.1 376280475 11728271 complement(775494..775673) 1 NC_016797.1 hypothetical protein 775673 11728271 BSVBI22_A0791 Brucella suis VBI22 hypothetical protein YP_005154481.1 775494 R 1112912 CDS YP_005154482.1 376280476 11728272 776005..776514 1 NC_016797.1 hypothetical protein 776514 11728272 BSVBI22_A0792 Brucella suis VBI22 hypothetical protein YP_005154482.1 776005 D 1112912 CDS YP_005154483.1 376280477 11728273 776511..776906 1 NC_016797.1 hypothetical protein 776906 11728273 BSVBI22_A0793 Brucella suis VBI22 hypothetical protein YP_005154483.1 776511 D 1112912 CDS YP_005154484.1 376280478 11728274 776960..777295 1 NC_016797.1 hypothetical protein 777295 11728274 BSVBI22_A0794 Brucella suis VBI22 hypothetical protein YP_005154484.1 776960 D 1112912 CDS YP_005154485.1 376280479 11728275 complement(777352..777753) 1 NC_016797.1 hypothetical protein 777753 11728275 BSVBI22_A0795 Brucella suis VBI22 hypothetical protein YP_005154485.1 777352 R 1112912 CDS YP_005154486.1 376280480 11728277 778050..778232 1 NC_016797.1 hypothetical protein 778232 11728277 BSVBI22_A0796 Brucella suis VBI22 hypothetical protein YP_005154486.1 778050 D 1112912 CDS YP_005154487.1 376280481 11728279 complement(778616..778819) 1 NC_016797.1 hypothetical protein 778819 11728279 BSVBI22_A0797 Brucella suis VBI22 hypothetical protein YP_005154487.1 778616 R 1112912 CDS YP_005154488.1 376280482 11728280 779327..779692 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 779692 nuoA 11728280 nuoA Brucella suis VBI22 NADH dehydrogenase subunit A YP_005154488.1 779327 D 1112912 CDS YP_005154489.1 376280483 11728281 779683..780264 1 NC_016797.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 780264 nuoB 11728281 nuoB Brucella suis VBI22 NADH dehydrogenase subunit B YP_005154489.1 779683 D 1112912 CDS YP_005154490.1 376280484 11728282 780377..780985 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 780985 nuoC 11728282 nuoC Brucella suis VBI22 NADH dehydrogenase subunit C YP_005154490.1 780377 D 1112912 CDS YP_005154491.1 376280485 11728283 781003..782193 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 782193 nuoD 11728283 nuoD Brucella suis VBI22 NADH dehydrogenase subunit D YP_005154491.1 781003 D 1112912 CDS YP_005154492.1 376280486 11728284 782193..782906 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 782906 nuoE 11728284 nuoE Brucella suis VBI22 NADH dehydrogenase subunit E YP_005154492.1 782193 D 1112912 CDS YP_005154493.1 376280487 11728285 782910..784217 1 NC_016797.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 784217 nuoF 11728285 nuoF Brucella suis VBI22 NADH dehydrogenase I subunit F YP_005154493.1 782910 D 1112912 CDS YP_005154494.1 376280488 11728286 784352..786436 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 786436 nuoG 11728286 nuoG Brucella suis VBI22 NADH dehydrogenase subunit G YP_005154494.1 784352 D 1112912 CDS YP_005154495.1 376280489 11728287 786456..787499 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 787499 nuoH 11728287 nuoH Brucella suis VBI22 NADH dehydrogenase subunit H YP_005154495.1 786456 D 1112912 CDS YP_005154496.1 376280490 11728288 787512..788003 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 788003 nuoI 11728288 nuoI Brucella suis VBI22 NADH dehydrogenase subunit I YP_005154496.1 787512 D 1112912 CDS YP_005154497.1 376280491 11728289 788177..788794 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 788794 nuoJ 11728289 nuoJ Brucella suis VBI22 NADH dehydrogenase subunit J YP_005154497.1 788177 D 1112912 CDS YP_005154498.1 376280492 11728290 788805..789113 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 789113 nuoK 11728290 nuoK Brucella suis VBI22 NADH dehydrogenase subunit K YP_005154498.1 788805 D 1112912 CDS YP_005154499.1 376280493 11728291 789121..791106 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 791106 nuoL 11728291 nuoL Brucella suis VBI22 NADH dehydrogenase subunit L YP_005154499.1 789121 D 1112912 CDS YP_005154500.1 376280494 11728292 791106..792614 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 792614 nuoM 11728292 nuoM Brucella suis VBI22 NADH dehydrogenase subunit M YP_005154500.1 791106 D 1112912 CDS YP_005154501.1 376280495 11728293 792636..794072 1 NC_016797.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 794072 nuoN 11728293 nuoN Brucella suis VBI22 NADH dehydrogenase subunit N YP_005154501.1 792636 D 1112912 CDS YP_005154502.1 376280496 11728294 794098..794895 1 NC_016797.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 794895 11728294 BSVBI22_A0812 Brucella suis VBI22 biotin--protein ligase YP_005154502.1 794098 D 1112912 CDS YP_005154503.1 376280497 11728295 795089..796765 1 NC_016797.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 796765 11728295 BSVBI22_A0813 Brucella suis VBI22 metallo-beta-lactamase family protein YP_005154503.1 795089 D 1112912 CDS YP_005154504.1 376280498 11728296 796805..797209 1 NC_016797.1 identified by match to protein family HMM PF00903; glyoxalase family protein 797209 11728296 BSVBI22_A0814 Brucella suis VBI22 glyoxalase family protein YP_005154504.1 796805 D 1112912 CDS YP_005154505.1 376280499 11728297 797212..797481 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1060; hypothetical protein 797481 11728297 BSVBI22_A0815 Brucella suis VBI22 hypothetical protein YP_005154505.1 797212 D 1112912 CDS YP_005154506.1 376280500 11728298 797839..797979 1 NC_016797.1 hypothetical protein 797979 11728298 BSVBI22_A0816 Brucella suis VBI22 hypothetical protein YP_005154506.1 797839 D 1112912 CDS YP_005154507.1 376280501 11728299 798010..798102 1 NC_016797.1 hypothetical protein 798102 11728299 BSVBI22_A0817 Brucella suis VBI22 hypothetical protein YP_005154507.1 798010 D 1112912 CDS YP_005154508.1 376280502 11728300 798329..799657 1 NC_016797.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 799657 proS 11728300 proS Brucella suis VBI22 prolyl-tRNA synthetase YP_005154508.1 798329 D 1112912 CDS YP_005154509.1 376280503 11728301 799699..800967 1 NC_016797.1 identified by match to protein family HMM PF02687; ABC transporter permease 800967 11728301 BSVBI22_A0819 Brucella suis VBI22 ABC transporter permease YP_005154509.1 799699 D 1112912 CDS YP_005154510.1 376280504 11728302 800967..801650 1 NC_016797.1 identified by similarity to SP:P75957; match to protein family HMM PF00005; lipoprotein releasing system ATP-binding protein LolD 801650 lolD 11728302 lolD Brucella suis VBI22 lipoprotein releasing system ATP-binding protein LolD YP_005154510.1 800967 D 1112912 CDS YP_005154511.1 376280505 11728303 802309..805800 1 NC_016797.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 805800 dnaE 11728303 dnaE Brucella suis VBI22 DNA polymerase III subunit alpha YP_005154511.1 802309 D 1112912 CDS YP_005154512.1 376280506 11728304 805841..806038 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0034; hypothetical protein 806038 11728304 BSVBI22_A0822 Brucella suis VBI22 hypothetical protein YP_005154512.1 805841 D 1112912 CDS YP_005154513.1 376280507 11728305 complement(806083..806496) 1 NC_016797.1 hypothetical protein 806496 11728305 BSVBI22_A0823 Brucella suis VBI22 hypothetical protein YP_005154513.1 806083 R 1112912 CDS YP_005154514.1 376280508 11728306 complement(806768..807739) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1990; hypothetical protein 807739 11728306 BSVBI22_A0824 Brucella suis VBI22 hypothetical protein YP_005154514.1 806768 R 1112912 CDS YP_005154515.1 376280509 11728307 807738..807902 1 NC_016797.1 hypothetical protein 807902 11728307 BSVBI22_A0825 Brucella suis VBI22 hypothetical protein YP_005154515.1 807738 D 1112912 CDS YP_005154516.1 376280510 11728308 808074..808691 1 NC_016797.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 808691 rpsD 11728308 rpsD Brucella suis VBI22 30S ribosomal protein S4 YP_005154516.1 808074 D 1112912 CDS YP_005154517.1 376280511 11728309 809200..810081 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0037; hypothetical protein 810081 11728309 BSVBI22_A0827 Brucella suis VBI22 hypothetical protein YP_005154517.1 809200 D 1112912 CDS YP_005154518.1 376280512 11728310 810068..810895 1 NC_016797.1 identified by match to protein family HMM PF00459; inositol monophosphatase family protein 810895 11728310 BSVBI22_A0828 Brucella suis VBI22 inositol monophosphatase family protein YP_005154518.1 810068 D 1112912 CDS YP_005154519.1 376280513 11728311 complement(811110..812375) 1 NC_016797.1 identified by match to protein family HMM PF00083; match to protein family HMM TIGR00710; Bcr/CflA subfamily drug resistance transporter 812375 11728311 BSVBI22_A0829 Brucella suis VBI22 Bcr/CflA subfamily drug resistance transporter YP_005154519.1 811110 R 1112912 CDS YP_005154520.1 376280514 11728312 812359..812559 1 NC_016797.1 hypothetical protein 812559 11728312 BSVBI22_A0830 Brucella suis VBI22 hypothetical protein YP_005154520.1 812359 D 1112912 CDS YP_005154521.1 376280515 11728313 complement(812646..813038) 1 NC_016797.1 identified by match to protein family HMM TIGR00365; glutaredoxin-like protein 813038 11728313 BSVBI22_A0831 Brucella suis VBI22 glutaredoxin-like protein YP_005154521.1 812646 R 1112912 CDS YP_005154522.1 376280516 11728314 complement(813163..813396) 1 NC_016797.1 identified by match to protein family HMM PF01722; BolA family protein 813396 11728314 BSVBI22_A0832 Brucella suis VBI22 BolA family protein YP_005154522.1 813163 R 1112912 CDS YP_005154523.1 376280517 11728315 complement(813666..815888) 1 NC_016797.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 815888 purL 11728315 purL Brucella suis VBI22 phosphoribosylformylglycinamidine synthase II YP_005154523.1 813666 R 1112912 CDS YP_005154524.1 376280518 11728316 complement(816075..816476) 1 NC_016797.1 putative lipoprotein 816476 11728316 BSVBI22_A0834 Brucella suis VBI22 putative lipoprotein YP_005154524.1 816075 R 1112912 CDS YP_005154525.1 376280519 11728317 complement(816536..817183) 1 NC_016797.1 identified by match to protein family HMM PF00043; glutathione S-transferase family protein 817183 11728317 BSVBI22_A0835 Brucella suis VBI22 glutathione S-transferase family protein YP_005154525.1 816536 R 1112912 CDS YP_005154526.1 376280520 11728318 complement(817435..818106) 1 NC_016797.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 818106 purQ 11728318 purQ Brucella suis VBI22 phosphoribosylformylglycinamidine synthase I YP_005154526.1 817435 R 1112912 CDS YP_005154527.1 376280521 11728319 complement(818129..818371) 1 NC_016797.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; phosphoribosylformylglycinamidine synthase subunit PurS 818371 11728319 BSVBI22_A0837 Brucella suis VBI22 phosphoribosylformylglycinamidine synthase subunit PurS YP_005154527.1 818129 R 1112912 CDS YP_005154528.1 376280522 11728320 complement(818487..819251) 1 NC_016797.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase 819251 purC 11728320 purC Brucella suis VBI22 phosphoribosylaminoimidazolesuccinocarboxamide synthase YP_005154528.1 818487 R 1112912 CDS YP_005154529.1 376280523 11728321 819507..819830 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0054; hypothetical protein 819830 11728321 BSVBI22_A0839 Brucella suis VBI22 hypothetical protein YP_005154529.1 819507 D 1112912 CDS YP_005154530.1 376280524 11728322 819895..820662 1 NC_016797.1 identified by similarity to EGAD:11526; match to protein family HMM PF03328; hydroxyacid aldolase 820662 11728322 BSVBI22_A0840 Brucella suis VBI22 hydroxyacid aldolase YP_005154530.1 819895 D 1112912 CDS YP_005154531.1 376280525 11728323 complement(820711..821277) 1 NC_016797.1 identified by similarity to GP:15074696; hypothetical protein 821277 11728323 BSVBI22_A0841 Brucella suis VBI22 hypothetical protein YP_005154531.1 820711 R 1112912 CDS YP_005154532.1 376280526 11728324 complement(821287..821388) 1 NC_016797.1 hypothetical protein 821388 11728324 BSVBI22_A0842 Brucella suis VBI22 hypothetical protein YP_005154532.1 821287 R 1112912 CDS YP_005154533.1 376280527 11728325 complement(821476..821577) 1 NC_016797.1 hypothetical protein 821577 11728325 BSVBI22_A0843 Brucella suis VBI22 hypothetical protein YP_005154533.1 821476 R 1112912 CDS YP_005154534.1 376280528 11728326 821630..822421 1 NC_016797.1 identified by match to protein family HMM PF00903; glyoxalase family protein 822421 11728326 BSVBI22_A0844 Brucella suis VBI22 glyoxalase family protein YP_005154534.1 821630 D 1112912 CDS YP_005154535.1 376280529 11728327 complement(822647..823948) 1 NC_016797.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 823948 purB 11728327 purB Brucella suis VBI22 adenylosuccinate lyase YP_005154535.1 822647 R 1112912 CDS YP_005154536.1 376280530 11728328 complement(823975..824652) 1 NC_016797.1 identified by similarity to EGAD:101737; match to protein family HMM PF00834; match to protein family HMM TIGR01163; ribulose-phosphate 3-epimerase 824652 rpe 11728328 rpe Brucella suis VBI22 ribulose-phosphate 3-epimerase YP_005154536.1 823975 R 1112912 CDS YP_005154537.1 376280531 11728329 complement(824810..825736) 1 NC_016797.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 825736 11728329 BSVBI22_A0847 Brucella suis VBI22 lipid A biosynthesis lauroyl acyltransferase YP_005154537.1 824810 R 1112912 CDS YP_005154538.1 376280532 11728330 complement(825750..826778) 1 NC_016797.1 identified by match to protein family HMM PF00107; zinc-containing alcohol dehydrogenase 826778 11728330 BSVBI22_A0848 Brucella suis VBI22 zinc-containing alcohol dehydrogenase YP_005154538.1 825750 R 1112912 CDS YP_005154539.1 376280533 11728331 complement(826860..828137) 1 NC_016797.1 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP.; 3-oxoacyl-(acyl carrier protein) synthase II 828137 11728331 BSVBI22_A0849 Brucella suis VBI22 3-oxoacyl-(acyl carrier protein) synthase II YP_005154539.1 826860 R 1112912 CDS YP_005154540.1 376280534 11728332 complement(828139..829320) 1 NC_016797.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 829320 11728332 BSVBI22_A0850 Brucella suis VBI22 3-oxoacyl-(acyl carrier protein) synthase II YP_005154540.1 828139 R 1112912 CDS YP_005154541.1 376280535 11728333 complement(829468..829749) 1 NC_016797.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; acyl carrier protein 829749 11728333 BSVBI22_A0851 Brucella suis VBI22 acyl carrier protein YP_005154541.1 829468 R 1112912 CDS YP_005154542.1 376280536 11728334 complement(829950..830711) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML6731; match to protein family HMM PF05838; hypothetical protein 830711 11728334 BSVBI22_A0852 Brucella suis VBI22 hypothetical protein YP_005154542.1 829950 R 1112912 CDS YP_005154543.1 376280537 11728335 830927..831949 1 NC_016797.1 identified by similarity to EGAD:30590; match to protein family HMM PF01263; aldose 1-epimerase 831949 galM 11728335 galM Brucella suis VBI22 aldose 1-epimerase YP_005154543.1 830927 D 1112912 CDS YP_005154544.1 376280538 11728336 complement(831946..832863) 1 NC_016797.1 identified by similarity to SP:P37647; match to protein family HMM PF00294; 2-dehydro-3-deoxygluconokinase 832863 11728336 BSVBI22_A0854 Brucella suis VBI22 2-dehydro-3-deoxygluconokinase YP_005154544.1 831946 R 1112912 CDS YP_005154545.1 376280539 11728337 833064..833795 1 NC_016797.1 identified by similarity to GP:15141057; hypothetical protein 833795 11728337 BSVBI22_A0855 Brucella suis VBI22 hypothetical protein YP_005154545.1 833064 D 1112912 CDS YP_005154546.1 376280540 11728338 833799..834938 1 NC_016797.1 identified by match to protein family HMM PF01979; PhnM protein 834938 phnM 11728338 phnM Brucella suis VBI22 PhnM protein YP_005154546.1 833799 D 1112912 CDS YP_005154547.1 376280541 11728339 complement(834935..835618) 1 NC_016797.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD superfamily hydrolase 835618 11728339 BSVBI22_A0857 Brucella suis VBI22 HAD superfamily hydrolase YP_005154547.1 834935 R 1112912 CDS YP_005154548.1 376280542 11728341 836855..837877 1 NC_016797.1 identified by similarity to OMNI:CC1306; match to protein family HMM PF01207; match to protein family HMM TIGR00742; tRNA-dihydrouridine synthase A 837877 11728341 BSVBI22_A0859 Brucella suis VBI22 tRNA-dihydrouridine synthase A YP_005154548.1 836855 D 1112912 CDS YP_005154549.1 376280543 11728342 complement(837874..838578) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0447; match to protein family HMM PF00077; hypothetical protein 838578 11728342 BSVBI22_A0860 Brucella suis VBI22 hypothetical protein YP_005154549.1 837874 R 1112912 CDS YP_005154550.1 376280544 11728343 complement(838578..838772) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0446; hypothetical protein 838772 11728343 BSVBI22_A0861 Brucella suis VBI22 hypothetical protein YP_005154550.1 838578 R 1112912 CDS YP_005154551.1 376280545 11728344 complement(838792..839574) 1 NC_016797.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 839574 cobS 11728344 cobS Brucella suis VBI22 cobalamin synthase YP_005154551.1 838792 R 1112912 CDS YP_005154552.1 376280546 11728345 839728..840747 1 NC_016797.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 840747 cobT 11728345 cobT Brucella suis VBI22 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_005154552.1 839728 D 1112912 CDS YP_005154553.1 376280547 11728346 complement(840855..841334) 1 NC_016797.1 identified by match to protein family HMM PF01037; AsnC family transcriptional regulator 841334 11728346 BSVBI22_A0864 Brucella suis VBI22 AsnC family transcriptional regulator YP_005154553.1 840855 R 1112912 CDS YP_005154554.1 376280548 11728347 complement(841463..842104) 1 NC_016797.1 identified by similarity to GP:15074814; hypothetical protein 842104 11728347 BSVBI22_A0865 Brucella suis VBI22 hypothetical protein YP_005154554.1 841463 R 1112912 CDS YP_005154555.1 376280549 11728348 complement(842201..842770) 1 NC_016797.1 identified by match to protein family HMM PF00565; nuclease domain-containing protein 842770 11728348 BSVBI22_A0866 Brucella suis VBI22 nuclease domain-containing protein YP_005154555.1 842201 R 1112912 CDS YP_005154556.1 376280550 11728349 842741..843019 1 NC_016797.1 hypothetical protein 843019 11728349 BSVBI22_A0867 Brucella suis VBI22 hypothetical protein YP_005154556.1 842741 D 1112912 CDS YP_005154557.1 376280551 11728350 843391..844194 1 NC_016797.1 identified by similarity to EGAD:35423; exopolysacchride production negative regulator exoR 844194 11728350 BSVBI22_A0868 Brucella suis VBI22 exopolysacchride production negative regulator exoR YP_005154557.1 843391 D 1112912 CDS YP_005154558.1 376280552 11728351 complement(844253..845035) 1 NC_016797.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633; exodeoxyribonuclease III 845035 xth-1 11728351 xth-1 Brucella suis VBI22 exodeoxyribonuclease III YP_005154558.1 844253 R 1112912 CDS YP_005154559.1 376280553 11728352 845204..845911 1 NC_016797.1 identified by similarity to GP:15075908; match to protein family HMM PF04391; hypothetical protein 845911 11728352 BSVBI22_A0870 Brucella suis VBI22 hypothetical protein YP_005154559.1 845204 D 1112912 CDS YP_005154560.1 376280554 11728353 complement(845992..846318) 1 NC_016797.1 identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; HesB/YadR/YfhF family protein 846318 11728353 BSVBI22_A0871 Brucella suis VBI22 HesB/YadR/YfhF family protein YP_005154560.1 845992 R 1112912 CDS YP_005154561.1 376280555 11728354 846485..847693 1 NC_016797.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 847693 dgt 11728354 dgt Brucella suis VBI22 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_005154561.1 846485 D 1112912 CDS YP_005154562.1 376280556 11728355 847915..849672 1 NC_016797.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 849672 argS 11728355 argS Brucella suis VBI22 arginyl-tRNA synthetase YP_005154562.1 847915 D 1112912 CDS YP_005154563.1 376280557 11728356 849884..852820 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0862; hypothetical protein 852820 11728356 BSVBI22_A0874 Brucella suis VBI22 hypothetical protein YP_005154563.1 849884 D 1112912 CDS YP_005154564.1 376280558 11728357 853021..854040 1 NC_016797.1 Beta-hexosaminidase 854040 11728357 BSVBI22_A0875 Brucella suis VBI22 Beta-hexosaminidase YP_005154564.1 853021 D 1112912 CDS YP_005154565.1 376280559 11728358 854227..854964 1 NC_016797.1 identified by similarity to GP:14021929; match to protein family HMM PF02616; segregation and condensation protein A 854964 scpA 11728358 scpA Brucella suis VBI22 segregation and condensation protein A YP_005154565.1 854227 D 1112912 CDS YP_005154566.1 376280560 11728359 854957..855682 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0859; match to protein family HMM PF04079; match to protein family HMM TIGR00281; segregation and condensation protein B 855682 scpB 11728359 scpB Brucella suis VBI22 segregation and condensation protein B YP_005154566.1 854957 D 1112912 CDS YP_005154567.1 376280561 11728360 855804..856046 1 NC_016797.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 856046 tatA 11728360 tatA Brucella suis VBI22 twin arginine translocase protein A YP_005154567.1 855804 D 1112912 CDS YP_005154568.1 376280562 11728361 856127..856738 1 NC_016797.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 856738 11728361 BSVBI22_A0879 Brucella suis VBI22 sec-independent translocase YP_005154568.1 856127 D 1112912 CDS YP_005154569.1 376280563 11728362 856735..857559 1 NC_016797.1 identified by similarity to EGAD:10132; match to protein family HMM PF00902; match to protein family HMM TIGR00945; Sec-independent protein translocase protein TatC 857559 tatC 11728362 tatC Brucella suis VBI22 Sec-independent protein translocase protein TatC YP_005154569.1 856735 D 1112912 CDS YP_005154570.1 376280564 11728363 857636..858919 1 NC_016797.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 858919 serS 11728363 serS Brucella suis VBI22 seryl-tRNA synthetase YP_005154570.1 857636 D 1112912 CDS YP_005154571.1 376280565 11728364 859068..859835 1 NC_016797.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 859835 surE 11728364 surE Brucella suis VBI22 stationary phase survival protein SurE YP_005154571.1 859068 D 1112912 CDS YP_005154572.1 376280566 11728365 859901..860500 1 NC_016797.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 860500 pcm 11728365 pcm Brucella suis VBI22 protein-L-isoaspartate O-methyltransferase YP_005154572.1 859901 D 1112912 CDS YP_005154573.1 376280567 11728366 860894..862177 1 NC_016797.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551; M24/M37 family peptidase 862177 11728366 BSVBI22_A0884 Brucella suis VBI22 M24/M37 family peptidase YP_005154573.1 860894 D 1112912 CDS YP_005154574.1 376280568 11728367 complement(862226..863092) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0849; match to protein family HMM PF05673; hypothetical protein 863092 11728367 BSVBI22_A0885 Brucella suis VBI22 hypothetical protein YP_005154574.1 862226 R 1112912 CDS YP_005154575.1 376280569 11728368 863252..863593 1 NC_016797.1 identified by similarity to SP:Q9ZG87; match to protein family HMM PF02699; match to protein family HMM TIGR00739; preprotein translocase subunit YajC 863593 11728368 BSVBI22_A0886 Brucella suis VBI22 preprotein translocase subunit YajC YP_005154575.1 863252 D 1112912 CDS YP_005154576.1 376280570 11728369 863682..866039 1 NC_016797.1 identified by similarity to GP:3220156; match to protein family HMM PF02355; match to protein family HMM TIGR00916; match to protein family HMM TIGR00966; match to protein family HMM TIGR01129; SecD/SecF family protein-export membrane protein 866039 11728369 BSVBI22_A0887 Brucella suis VBI22 SecD/SecF family protein-export membrane protein YP_005154576.1 863682 D 1112912 CDS YP_005154577.1 376280571 11728370 866042..866431 1 NC_016797.1 identified by similarity to GP:14021915; match to protein family HMM PF04635; hypothetical protein 866431 11728370 BSVBI22_A0888 Brucella suis VBI22 hypothetical protein YP_005154577.1 866042 D 1112912 CDS YP_005154578.1 376280572 11728371 866437..867270 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0845; hypothetical protein 867270 11728371 BSVBI22_A0889 Brucella suis VBI22 hypothetical protein YP_005154578.1 866437 D 1112912 CDS YP_005154579.1 376280573 11728372 complement(867322..868722) 1 NC_016797.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 868722 11728372 BSVBI22_A0890 Brucella suis VBI22 tRNA (uracil-5-)-methyltransferase Gid YP_005154579.1 867322 R 1112912 CDS YP_005154580.1 376280574 11728373 complement(868982..869128) 1 NC_016797.1 identified by similarity to GP:15074478; hypothetical protein 869128 11728373 BSVBI22_A0891 Brucella suis VBI22 hypothetical protein YP_005154580.1 868982 R 1112912 CDS YP_005154581.1 376280575 11728374 869402..870538 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0840; hypothetical protein 870538 11728374 BSVBI22_A0892 Brucella suis VBI22 hypothetical protein YP_005154581.1 869402 D 1112912 CDS YP_005154582.1 376280576 11728375 870535..871104 1 NC_016797.1 hypothetical protein 871104 11728375 BSVBI22_A0893 Brucella suis VBI22 hypothetical protein YP_005154582.1 870535 D 1112912 CDS YP_005154583.1 376280577 11728377 871484..872941 1 NC_016797.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 872941 tig 11728377 tig Brucella suis VBI22 trigger factor YP_005154583.1 871484 D 1112912 CDS YP_005154584.1 376280578 11728378 873091..874593 1 NC_016797.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 874593 gatB 11728378 gatB Brucella suis VBI22 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_005154584.1 873091 D 1112912 CDS YP_005154585.1 376280579 11728379 874593..875096 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 875096 11728379 BSVBI22_A0896 Brucella suis VBI22 acetyltransferase YP_005154585.1 874593 D 1112912 CDS YP_005154586.1 376280580 11728380 complement(875141..875284) 1 NC_016797.1 hypothetical protein 875284 11728380 BSVBI22_A0897 Brucella suis VBI22 hypothetical protein YP_005154586.1 875141 R 1112912 CDS YP_005154587.1 376280581 11728381 875256..875666 1 NC_016797.1 Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis; NADH dehydrogenase 875666 11728381 BSVBI22_A0898 Brucella suis VBI22 NADH dehydrogenase YP_005154587.1 875256 D 1112912 CDS YP_005154588.1 376280582 11728382 875726..875851 1 NC_016797.1 hypothetical protein 875851 11728382 BSVBI22_A0899 Brucella suis VBI22 hypothetical protein YP_005154588.1 875726 D 1112912 CDS YP_005154589.1 376280583 11728383 875860..876330 1 NC_016797.1 identified by similarity to GP:15074249; hypothetical protein 876330 11728383 BSVBI22_A0900 Brucella suis VBI22 hypothetical protein YP_005154589.1 875860 D 1112912 CDS YP_005154590.1 376280584 11728384 complement(876374..876907) 1 NC_016797.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 876907 aat 11728384 aat Brucella suis VBI22 leucyl/phenylalanyl-tRNA--protein transferase YP_005154590.1 876374 R 1112912 CDS YP_005154591.1 376280585 11728385 complement(876995..878353) 1 NC_016797.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 878353 accC 11728385 accC Brucella suis VBI22 acetyl-CoA carboxylase biotin carboxylase subunit YP_005154591.1 876995 R 1112912 CDS YP_005154592.1 376280586 11728386 complement(878403..878873) 1 NC_016797.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 878873 accB 11728386 accB Brucella suis VBI22 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_005154592.1 878403 R 1112912 CDS YP_005154593.1 376280587 11728387 complement(878875..879348) 1 NC_016797.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 879348 aroQ 11728387 aroQ Brucella suis VBI22 3-dehydroquinate dehydratase YP_005154593.1 878875 R 1112912 CDS YP_005154594.1 376280588 11728388 complement(879592..880389) 1 NC_016797.1 identified by match to protein family HMM PF01323; outer membrane protein 880389 11728388 BSVBI22_A0905 Brucella suis VBI22 outer membrane protein YP_005154594.1 879592 R 1112912 CDS YP_005154595.1 376280589 11728389 complement(880437..881852) 1 NC_016797.1 identified by similarity to GP:14021229; match to protein family HMM PF01435; hypothetical protein 881852 11728389 BSVBI22_A0906 Brucella suis VBI22 hypothetical protein YP_005154595.1 880437 R 1112912 CDS YP_005154596.1 376280590 11728390 882044..883207 1 NC_016797.1 identified by match to protein family HMM PF00155; class I aminotransferase 883207 11728390 BSVBI22_A0907 Brucella suis VBI22 class I aminotransferase YP_005154596.1 882044 D 1112912 CDS YP_005154597.1 376280591 11728391 complement(883326..886094) 1 NC_016797.1 identified by match to protein family HMM TIGR00757; ribonuclease Rne/Rng domain-containing protein 886094 11728391 BSVBI22_A0908 Brucella suis VBI22 ribonuclease Rne/Rng domain-containing protein YP_005154597.1 883326 R 1112912 CDS YP_005154598.1 376280592 11728392 886097..886282 1 NC_016797.1 hypothetical protein 886282 11728392 BSVBI22_A0909 Brucella suis VBI22 hypothetical protein YP_005154598.1 886097 D 1112912 CDS YP_005154599.1 376280593 11728393 complement(886634..886735) 1 NC_016797.1 hypothetical protein 886735 11728393 BSVBI22_A0910 Brucella suis VBI22 hypothetical protein YP_005154599.1 886634 R 1112912 CDS YP_005154600.1 376280594 11728394 886773..888041 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0166; match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase 888041 11728394 BSVBI22_A0911 Brucella suis VBI22 N-acetylmuramoyl-L-alanine amidase YP_005154600.1 886773 D 1112912 CDS YP_005154601.1 376280595 11728395 888321..890780 1 NC_016797.1 identified by similarity to SP:P02918; match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 1A 890780 11728395 BSVBI22_A0912 Brucella suis VBI22 penicillin-binding protein 1A YP_005154601.1 888321 D 1112912 CDS YP_005154602.1 376280596 11728397 complement(892108..892272) 1 NC_016797.1 hypothetical protein 892272 11728397 BSVBI22_A0914 Brucella suis VBI22 hypothetical protein YP_005154602.1 892108 R 1112912 CDS YP_005154603.1 376280597 11728398 892265..892576 1 NC_016797.1 identified by similarity to EGAD:46813; IS711, transposase orfA 892576 11728398 BSVBI22_A0915 Brucella suis VBI22 IS711, transposase orfA YP_005154603.1 892265 D 1112912 CDS YP_005154604.1 376280598 11728400 complement(893055..893156) 1 NC_016797.1 hypothetical protein 893156 11728400 BSVBI22_A0917 Brucella suis VBI22 hypothetical protein YP_005154604.1 893055 R 1112912 CDS YP_005154605.1 376280599 11728401 complement(893153..893419) 1 NC_016797.1 hypothetical protein 893419 11728401 BSVBI22_A0918 Brucella suis VBI22 hypothetical protein YP_005154605.1 893153 R 1112912 CDS YP_005154606.1 376280600 11728402 complement(893686..894513) 1 NC_016797.1 identified by similarity to GP:15074676; match to protein family HMM PF04305; hypothetical protein 894513 11728402 BSVBI22_A0919 Brucella suis VBI22 hypothetical protein YP_005154606.1 893686 R 1112912 CDS YP_005154607.1 376280601 11728403 complement(894535..894999) 1 NC_016797.1 identified by similarity to EGAD:18740; match to protein family HMM PF00578; bacterioferritin comigratory protein 894999 bcp 11728403 bcp Brucella suis VBI22 bacterioferritin comigratory protein YP_005154607.1 894535 R 1112912 CDS YP_005154608.1 376280602 11728404 895244..898684 1 NC_016797.1 identified by similarity to GP:14021072; hypothetical protein 898684 11728404 BSVBI22_A0921 Brucella suis VBI22 hypothetical protein YP_005154608.1 895244 D 1112912 CDS YP_005154609.1 376280603 11728405 complement(898743..899996) 1 NC_016797.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 899996 tyrS 11728405 tyrS Brucella suis VBI22 tyrosyl-tRNA synthetase YP_005154609.1 898743 R 1112912 CDS YP_005154610.1 376280604 11728406 900112..901233 1 NC_016797.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 901233 anmK 11728406 anmK Brucella suis VBI22 anhydro-N-acetylmuramic acid kinase YP_005154610.1 900112 D 1112912 CDS YP_005154611.1 376280605 11728407 complement(901230..901562) 1 NC_016797.1 identified by similarity to GP:12024949; match to protein family HMM PF00893; quaternary ammonium compound-resistance protein 901562 qacH 11728407 qacH Brucella suis VBI22 quaternary ammonium compound-resistance protein YP_005154611.1 901230 R 1112912 CDS YP_005154612.1 376280606 11728408 complement(901674..902348) 1 NC_016797.1 identified by similarity to GP:15074671; hypothetical protein 902348 11728408 BSVBI22_A0925 Brucella suis VBI22 hypothetical protein YP_005154612.1 901674 R 1112912 CDS YP_005154613.1 376280607 11728409 902553..903731 1 NC_016797.1 identified by similarity to EGAD:14639; match to protein family HMM PF00266; cysteine desulfurase 903731 11728409 BSVBI22_A0926 Brucella suis VBI22 cysteine desulfurase YP_005154613.1 902553 D 1112912 CDS YP_005154614.1 376280608 11728410 903912..905435 1 NC_016797.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 905435 11728410 BSVBI22_A0927 Brucella suis VBI22 cysteine desulfurase activator complex subunit SufB YP_005154614.1 903912 D 1112912 CDS YP_005154615.1 376280609 11728411 905503..906258 1 NC_016797.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978; ABC transporter ATP-binding protein 906258 11728411 BSVBI22_A0928 Brucella suis VBI22 ABC transporter ATP-binding protein YP_005154615.1 905503 D 1112912 CDS YP_005154616.1 376280610 11728412 906272..907549 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0017; match to protein family HMM PF01458; match to protein family HMM TIGR01981; hypothetical protein 907549 11728412 BSVBI22_A0929 Brucella suis VBI22 hypothetical protein YP_005154616.1 906272 D 1112912 CDS YP_005154617.1 376280611 11728413 907631..908875 1 NC_016797.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR01979; class V aminotransferase 908875 11728413 BSVBI22_A0930 Brucella suis VBI22 class V aminotransferase YP_005154617.1 907631 D 1112912 CDS YP_005154618.1 376280612 11728414 908872..909291 1 NC_016797.1 identified by similarity to GP:14021086; match to protein family HMM PF01883; hypothetical protein 909291 11728414 BSVBI22_A0931 Brucella suis VBI22 hypothetical protein YP_005154618.1 908872 D 1112912 CDS YP_005154619.1 376280613 11728415 complement(909325..910296) 1 NC_016797.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 910296 11728415 BSVBI22_A0932 Brucella suis VBI22 glycosyl transferase family protein YP_005154619.1 909325 R 1112912 CDS YP_005154620.1 376280614 11728417 910699..911496 1 NC_016797.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 911496 ppnK 11728417 ppnK Brucella suis VBI22 inorganic polyphosphate/ATP-NAD kinase YP_005154620.1 910699 D 1112912 CDS YP_005154621.1 376280615 11728418 911824..913272 1 NC_016797.1 identified by similarity to EGAD:20681; match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD/DEAH box helicase 913272 11728418 BSVBI22_A0934 Brucella suis VBI22 DEAD/DEAH box helicase YP_005154621.1 911824 D 1112912 CDS YP_005154622.1 376280616 11728419 complement(913509..913889) 1 NC_016797.1 identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; HesB/YadR/YfhF family protein 913889 11728419 BSVBI22_A0935 Brucella suis VBI22 HesB/YadR/YfhF family protein YP_005154622.1 913509 R 1112912 CDS YP_005154623.1 376280617 11728420 914082..914705 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0072; hypothetical protein 914705 11728420 BSVBI22_A0936 Brucella suis VBI22 hypothetical protein YP_005154623.1 914082 D 1112912 CDS YP_005154624.1 376280618 11728421 914690..914782 1 NC_016797.1 hypothetical protein 914782 11728421 BSVBI22_A0937 Brucella suis VBI22 hypothetical protein YP_005154624.1 914690 D 1112912 CDS YP_005154625.1 376280619 11728422 914786..914986 1 NC_016797.1 identified by match to protein family HMM PF00403; heavy metal-binding domain-containing protein 914986 11728422 BSVBI22_A0938 Brucella suis VBI22 heavy metal-binding domain-containing protein YP_005154625.1 914786 D 1112912 CDS YP_005154626.1 376280620 11728423 915030..915275 1 NC_016797.1 hypothetical protein 915275 11728423 BSVBI22_A0939 Brucella suis VBI22 hypothetical protein YP_005154626.1 915030 D 1112912 CDS YP_005154627.1 376280621 11728424 915313..915981 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0876; match to protein family HMM PF01135; protein-L-isoaspartate O-methyltransferase, putative 915981 11728424 BSVBI22_A0940 Brucella suis VBI22 protein-L-isoaspartate O-methyltransferase, putative YP_005154627.1 915313 D 1112912 CDS YP_005154628.1 376280622 11728425 916120..917490 1 NC_016797.1 identified by match to protein family HMM PF02321; match to protein family HMM TIGR01844; outer membrane efflux family protein 917490 11728425 BSVBI22_A0941 Brucella suis VBI22 outer membrane efflux family protein YP_005154628.1 916120 D 1112912 CDS YP_005154629.1 376280623 11728426 917740..918471 1 NC_016797.1 identified by similarity to GP:14021943; hypothetical protein 918471 11728426 BSVBI22_A0942 Brucella suis VBI22 hypothetical protein YP_005154629.1 917740 D 1112912 CDS YP_005154630.1 376280624 11728427 918566..918769 1 NC_016797.1 hypothetical protein 918769 11728427 BSVBI22_A0943 Brucella suis VBI22 hypothetical protein YP_005154630.1 918566 D 1112912 CDS YP_005154631.1 376280625 11728428 918762..921494 1 NC_016797.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 921494 valS 11728428 valS Brucella suis VBI22 valyl-tRNA synthetase YP_005154631.1 918762 D 1112912 CDS YP_005154632.1 376280626 11728430 complement(923252..924127) 1 NC_016797.1 identified by match to protein family HMM PF03446; oxidoreductase 924127 11728430 BSVBI22_A0946 Brucella suis VBI22 oxidoreductase YP_005154632.1 923252 R 1112912 CDS YP_005154633.1 376280627 11728431 complement(924155..924775) 1 NC_016797.1 identified by match to protein family HMM PF02798; glutathione S-transferase domain-containing protein 924775 11728431 BSVBI22_A0947 Brucella suis VBI22 glutathione S-transferase domain-containing protein YP_005154633.1 924155 R 1112912 CDS YP_005154634.1 376280628 11728432 complement(924948..925781) 1 NC_016797.1 identified by similarity to EGAD:6543; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 925781 11728432 BSVBI22_A0948 Brucella suis VBI22 amino acid ABC transporter permease YP_005154634.1 924948 R 1112912 CDS YP_005154635.1 376280629 11728433 complement(925784..926506) 1 NC_016797.1 identified by similarity to EGAD:8421; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 926506 11728433 BSVBI22_A0949 Brucella suis VBI22 amino acid ABC transporter permease YP_005154635.1 925784 R 1112912 CDS YP_005154636.1 376280630 11728434 complement(926522..926701) 1 NC_016797.1 hypothetical protein 926701 11728434 BSVBI22_A0950 Brucella suis VBI22 hypothetical protein YP_005154636.1 926522 R 1112912 CDS YP_005154637.1 376280631 11728435 complement(926749..927555) 1 NC_016797.1 identified by similarity to EGAD:37042; match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 927555 11728435 BSVBI22_A0951 Brucella suis VBI22 amino acid ABC transporter substrate-binding protein YP_005154637.1 926749 R 1112912 CDS YP_005154638.1 376280632 11728436 complement(927900..928403) 1 NC_016797.1 identified by similarity to SP:P32125; match to protein family HMM PF03205; match to protein family HMM TIGR00176; molybdopterin-guanine dinucleotide biosynthesis protein MobB 928403 mobB 11728436 mobB Brucella suis VBI22 molybdopterin-guanine dinucleotide biosynthesis protein MobB YP_005154638.1 927900 R 1112912 CDS YP_005154639.1 376280633 11728437 complement(928400..929065) 1 NC_016797.1 identified by similarity to SP:P32173; molybdopterin-guanine dinucleotide biosynthesis protein MobA 929065 mobA 11728437 mobA Brucella suis VBI22 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_005154639.1 928400 R 1112912 CDS YP_005154640.1 376280634 11728438 complement(929241..930275) 1 NC_016797.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 930275 moaA 11728438 moaA Brucella suis VBI22 molybdenum cofactor biosynthesis protein A YP_005154640.1 929241 R 1112912 CDS YP_005154641.1 376280635 11728439 930462..930821 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0426; hypothetical protein 930821 11728439 BSVBI22_A0955 Brucella suis VBI22 hypothetical protein YP_005154641.1 930462 D 1112912 CDS YP_005154642.1 376280636 11728440 complement(930889..931995) 1 NC_016797.1 identified by match to protein family HMM PF01360; monooxygenase FAD-binding protein 931995 11728440 BSVBI22_A0956 Brucella suis VBI22 monooxygenase FAD-binding protein YP_005154642.1 930889 R 1112912 CDS YP_005154643.1 376280637 11728441 complement(932339..933958) 1 NC_016797.1 identified by similarity to SP:P00923; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase, class I 933958 fumB 11728441 fumB Brucella suis VBI22 fumarate hydratase, class I YP_005154643.1 932339 R 1112912 CDS YP_005154644.1 376280638 11728442 934474..936192 1 NC_016797.1 identified by similarity to GP:15156702; hypothetical protein 936192 11728442 BSVBI22_A0958 Brucella suis VBI22 hypothetical protein YP_005154644.1 934474 D 1112912 CDS YP_005154645.1 376280639 11728444 complement(936687..936812) 1 NC_016797.1 hypothetical protein 936812 11728444 BSVBI22_A0959 Brucella suis VBI22 hypothetical protein YP_005154645.1 936687 R 1112912 CDS YP_005154646.1 376280640 11728446 complement(936993..937244) 1 NC_016797.1 identified by similarity to GP:15159178; match to protein family HMM PF04226; hypothetical protein 937244 11728446 BSVBI22_A0960 Brucella suis VBI22 hypothetical protein YP_005154646.1 936993 R 1112912 CDS YP_005154647.1 376280641 11728447 937399..937560 1 NC_016797.1 hypothetical protein 937560 11728447 BSVBI22_A0961 Brucella suis VBI22 hypothetical protein YP_005154647.1 937399 D 1112912 CDS YP_005154648.1 376280642 11728449 complement(937753..938778) 1 NC_016797.1 identified by match to protein family HMM PF00589; phage integrase family site specific recombinase 938778 11728449 BSVBI22_A0962 Brucella suis VBI22 phage integrase family site specific recombinase YP_005154648.1 937753 R 1112912 CDS YP_005154649.1 376280643 11728450 938953..940155 1 NC_016797.1 hypothetical protein 940155 11728450 BSVBI22_A0963 Brucella suis VBI22 hypothetical protein YP_005154649.1 938953 D 1112912 CDS YP_005154650.1 376280644 11728451 940152..940382 1 NC_016797.1 hypothetical protein 940382 11728451 BSVBI22_A0964 Brucella suis VBI22 hypothetical protein YP_005154650.1 940152 D 1112912 CDS YP_005154651.1 376280645 11728452 940379..940654 1 NC_016797.1 hypothetical protein 940654 11728452 BSVBI22_A0965 Brucella suis VBI22 hypothetical protein YP_005154651.1 940379 D 1112912 CDS YP_005154652.1 376280646 11728453 940677..941264 1 NC_016797.1 hypothetical protein 941264 11728453 BSVBI22_A0966 Brucella suis VBI22 hypothetical protein YP_005154652.1 940677 D 1112912 CDS YP_005154653.1 376280647 11728454 941499..942209 1 NC_016797.1 identified by similarity to EGAD:151783; outer membrane protein 942209 11728454 BSVBI22_A0967 Brucella suis VBI22 outer membrane protein YP_005154653.1 941499 D 1112912 CDS YP_005154654.1 376280648 11728455 complement(942557..942727) 1 NC_016797.1 identified by similarity to EGAD:176501; hypothetical protein 942727 11728455 BSVBI22_A0968 Brucella suis VBI22 hypothetical protein YP_005154654.1 942557 R 1112912 CDS YP_005154655.1 376280649 11728456 942745..942924 1 NC_016797.1 hypothetical protein 942924 11728456 BSVBI22_A0969 Brucella suis VBI22 hypothetical protein YP_005154655.1 942745 D 1112912 CDS YP_005154656.1 376280650 11728457 complement(943075..943389) 1 NC_016797.1 identified by similarity to GP:15073548; hypothetical protein 943389 11728457 BSVBI22_A0970 Brucella suis VBI22 hypothetical protein YP_005154656.1 943075 R 1112912 CDS YP_005154657.1 376280651 11728458 complement(943389..943709) 1 NC_016797.1 identified by similarity to GP:15073547; hypothetical protein 943709 11728458 BSVBI22_A0971 Brucella suis VBI22 hypothetical protein YP_005154657.1 943389 R 1112912 CDS YP_005154658.1 376280652 11728460 944497..944808 1 NC_016797.1 identified by similarity to EGAD:46813; IS711, transposase orfA 944808 11728460 BSVBI22_A0973 Brucella suis VBI22 IS711, transposase orfA YP_005154658.1 944497 D 1112912 CDS YP_005154659.1 376280653 11728462 945288..946007 1 NC_016797.1 hypothetical protein 946007 11728462 BSVBI22_A0975 Brucella suis VBI22 hypothetical protein YP_005154659.1 945288 D 1112912 CDS YP_005154660.1 376280654 11728463 946142..947788 1 NC_016797.1 hypothetical protein 947788 11728463 BSVBI22_A0976 Brucella suis VBI22 hypothetical protein YP_005154660.1 946142 D 1112912 CDS YP_005154661.1 376280655 11728464 948114..949346 1 NC_016797.1 identified by similarity to GP:5616097; glycosyl transferase WboA 949346 11728464 BSVBI22_A0977 Brucella suis VBI22 glycosyl transferase WboA YP_005154661.1 948114 D 1112912 CDS YP_005154662.1 376280656 11728465 949343..950902 1 NC_016797.1 identified by similarity to EGAD:103475; match to protein family HMM PF00534; glycoside hydrolase family protein 950902 11728465 BSVBI22_A0978 Brucella suis VBI22 glycoside hydrolase family protein YP_005154662.1 949343 D 1112912 CDS YP_005154663.1 376280657 11728466 complement(950883..951104) 1 NC_016797.1 hypothetical protein 951104 11728466 BSVBI22_A0979 Brucella suis VBI22 hypothetical protein YP_005154663.1 950883 R 1112912 CDS YP_005154664.1 376280658 11728467 951345..952007 1 NC_016797.1 identified by similarity to OMNI:PG0293; match to protein family HMM PF05838; secretion activator protein 952007 11728467 BSVBI22_A0980 Brucella suis VBI22 secretion activator protein YP_005154664.1 951345 D 1112912 CDS YP_005154665.1 376280659 11728468 complement(951971..952240) 1 NC_016797.1 hypothetical protein 952240 11728468 BSVBI22_A0981 Brucella suis VBI22 hypothetical protein YP_005154665.1 951971 R 1112912 CDS YP_005154666.1 376280660 11728469 952376..952627 1 NC_016797.1 hypothetical protein 952627 11728469 BSVBI22_A0982 Brucella suis VBI22 hypothetical protein YP_005154666.1 952376 D 1112912 CDS YP_005154667.1 376280661 11728470 952729..952830 1 NC_016797.1 hypothetical protein 952830 11728470 BSVBI22_A0983 Brucella suis VBI22 hypothetical protein YP_005154667.1 952729 D 1112912 CDS YP_005154668.1 376280662 11728471 952836..952976 1 NC_016797.1 hypothetical protein 952976 11728471 BSVBI22_A0984 Brucella suis VBI22 hypothetical protein YP_005154668.1 952836 D 1112912 CDS YP_005154669.1 376280663 11728472 952967..953314 1 NC_016797.1 identified by similarity to EGAD:91898; match to protein family HMM PF03960; match to protein family HMM TIGR00014; arsenate reductase ArsC 953314 11728472 BSVBI22_A0985 Brucella suis VBI22 arsenate reductase ArsC YP_005154669.1 952967 D 1112912 CDS YP_005154670.1 376280664 11728473 953685..954950 1 NC_016797.1 identified by match to protein family HMM PF03330; match to protein family HMM TIGR00413; rare lipoprotein A family protein 954950 11728473 BSVBI22_A0986 Brucella suis VBI22 rare lipoprotein A family protein YP_005154670.1 953685 D 1112912 CDS YP_005154671.1 376280665 11728474 955061..956251 1 NC_016797.1 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 956251 11728474 BSVBI22_A0987 Brucella suis VBI22 D-alanyl-D-alanine carboxypeptidase YP_005154671.1 955061 D 1112912 CDS YP_005154672.1 376280666 11728475 956342..956977 1 NC_016797.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 956977 tmk 11728475 tmk Brucella suis VBI22 thymidylate kinase YP_005154672.1 956342 D 1112912 CDS YP_005154673.1 376280667 11728476 956974..958056 1 NC_016797.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 958056 11728476 BSVBI22_A0989 Brucella suis VBI22 DNA polymerase III subunit delta' YP_005154673.1 956974 D 1112912 CDS YP_005154674.1 376280668 11728477 958076..958225 1 NC_016797.1 hypothetical protein 958225 11728477 BSVBI22_A0990 Brucella suis VBI22 hypothetical protein YP_005154674.1 958076 D 1112912 CDS YP_005154675.1 376280669 11728478 958225..959772 1 NC_016797.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 959772 metG 11728478 metG Brucella suis VBI22 methionyl-tRNA synthetase YP_005154675.1 958225 D 1112912 CDS YP_005154676.1 376280670 11728479 959781..960572 1 NC_016797.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; TatD family hydrolase 960572 11728479 BSVBI22_A0992 Brucella suis VBI22 TatD family hydrolase YP_005154676.1 959781 D 1112912 CDS YP_005154677.1 376280671 11728480 960575..961393 1 NC_016797.1 identified by similarity to GP:15074532; match to protein family HMM PF00753; hypothetical protein 961393 11728480 BSVBI22_A0993 Brucella suis VBI22 hypothetical protein YP_005154677.1 960575 D 1112912 CDS YP_005154678.1 376280672 11728481 complement(961443..963242) 1 NC_016797.1 responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease component; Cgt; ChvA; NdvA; cyclic beta-1,2-glucan ABc transporter 963242 11728481 BSVBI22_A0994 Brucella suis VBI22 cyclic beta-1,2-glucan ABc transporter YP_005154678.1 961443 R 1112912 CDS YP_005154679.1 376280673 11728482 963331..963435 1 NC_016797.1 hypothetical protein 963435 11728482 BSVBI22_A0995 Brucella suis VBI22 hypothetical protein YP_005154679.1 963331 D 1112912 CDS YP_005154680.1 376280674 11728483 963555..964535 1 NC_016797.1 identified by similarity to EGAD:7861; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase C 964535 rluC 11728483 rluC Brucella suis VBI22 ribosomal large subunit pseudouridine synthase C YP_005154680.1 963555 D 1112912 CDS YP_005154681.1 376280675 11728484 964538..965461 1 NC_016797.1 identified by match to protein family HMM PF00892; hypothetical protein 965461 11728484 BSVBI22_A0997 Brucella suis VBI22 hypothetical protein YP_005154681.1 964538 D 1112912 CDS YP_005154682.1 376280676 11728485 965458..966123 1 NC_016797.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD superfamily hydrolase 966123 11728485 BSVBI22_A0998 Brucella suis VBI22 HAD superfamily hydrolase YP_005154682.1 965458 D 1112912 CDS YP_005154683.1 376280677 11728486 966165..966947 1 NC_016797.1 identified by similarity to GP:15156553; hypothetical protein 966947 11728486 BSVBI22_A0999 Brucella suis VBI22 hypothetical protein YP_005154683.1 966165 D 1112912 CDS YP_005154684.1 376280678 11728487 complement(967073..968482) 1 NC_016797.1 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; glutamine synthetase, type I 968482 glnA 11728487 glnA Brucella suis VBI22 glutamine synthetase, type I YP_005154684.1 967073 R 1112912 CDS YP_005154685.1 376280679 11728488 complement(968630..968968) 1 NC_016797.1 identified by similarity to EGAD:35417; match to protein family HMM PF00543; nitrogen regulatory protein P-II 968968 glnB 11728488 glnB Brucella suis VBI22 nitrogen regulatory protein P-II YP_005154685.1 968630 R 1112912 CDS YP_005154686.1 376280680 11728489 969275..970780 1 NC_016797.1 identified by similarity to OMNI:CC1965; match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197; YjeF family protein 970780 11728489 BSVBI22_A1002 Brucella suis VBI22 YjeF family protein YP_005154686.1 969275 D 1112912 CDS YP_005154687.1 376280681 11728490 complement(970811..971083) 1 NC_016797.1 hypothetical protein 971083 11728490 BSVBI22_A1003 Brucella suis VBI22 hypothetical protein YP_005154687.1 970811 R 1112912 CDS YP_005154688.1 376280682 11728491 complement(971080..971784) 1 NC_016797.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 971784 cbbZ 11728491 cbbZ Brucella suis VBI22 phosphoglycolate phosphatase YP_005154688.1 971080 R 1112912 CDS YP_005154689.1 376280683 11728492 971839..971952 1 NC_016797.1 hypothetical protein 971952 11728492 BSVBI22_A1005 Brucella suis VBI22 hypothetical protein YP_005154689.1 971839 D 1112912 CDS YP_005154690.1 376280684 11728493 972131..972829 1 NC_016797.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 972829 rpiA 11728493 rpiA Brucella suis VBI22 ribose-5-phosphate isomerase A YP_005154690.1 972131 D 1112912 CDS YP_005154691.1 376280685 11728494 972855..973391 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0413; hypothetical protein 973391 11728494 BSVBI22_A1007 Brucella suis VBI22 hypothetical protein YP_005154691.1 972855 D 1112912 CDS YP_005154692.1 376280686 11728495 973545..974939 1 NC_016797.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 974939 gor 11728495 gor Brucella suis VBI22 glutathione reductase YP_005154692.1 973545 D 1112912 CDS YP_005154693.1 376280687 11728496 975148..976536 1 NC_016797.1 identified by match to protein family HMM PF01474; match to protein family HMM TIGR01358; phospho-2-dehydro-3-deoxyheptonate aldolase 976536 dhs 11728496 dhs Brucella suis VBI22 phospho-2-dehydro-3-deoxyheptonate aldolase YP_005154693.1 975148 D 1112912 CDS YP_005154694.1 376280688 11728497 976640..976990 1 NC_016797.1 identified by similarity to SP:P00556; match to protein family HMM PF01219; diacylglycerol kinase 976990 dgkA 11728497 dgkA Brucella suis VBI22 diacylglycerol kinase YP_005154694.1 976640 D 1112912 CDS YP_005154695.1 376280689 11728498 977082..978734 1 NC_016797.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 978734 nadE 11728498 nadE Brucella suis VBI22 NAD synthetase YP_005154695.1 977082 D 1112912 CDS YP_005154696.1 376280690 11728499 978746..980119 1 NC_016797.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 980119 gltX 11728499 gltX Brucella suis VBI22 glutamyl-tRNA synthetase YP_005154696.1 978746 D 1112912 CDS YP_005154697.1 376280691 11728500 complement(980933..983257) 1 NC_016797.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 983257 maeB 11728500 maeB Brucella suis VBI22 malic enzyme YP_005154697.1 980933 R 1112912 CDS YP_005154698.1 376280692 11728501 complement(983475..984455) 1 NC_016797.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase/muconate lactonizing protein 984455 11728501 BSVBI22_A1014 Brucella suis VBI22 mandelate racemase/muconate lactonizing protein YP_005154698.1 983475 R 1112912 CDS YP_005154699.1 376280693 11728502 984516..985691 1 NC_016797.1 identified by match to protein family HMM PF01740; match to protein family HMM PF02405; toulene ABC transporter permease 985691 11728502 BSVBI22_A1015 Brucella suis VBI22 toulene ABC transporter permease YP_005154699.1 984516 D 1112912 CDS YP_005154700.1 376280694 11728503 985908..986765 1 NC_016797.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 986765 11728503 BSVBI22_A1016 Brucella suis VBI22 ABC transporter ATP-binding protein YP_005154700.1 985908 D 1112912 CDS YP_005154701.1 376280695 11728504 986769..987764 1 NC_016797.1 identified by match to protein family HMM PF02470; ABC transporter periplasmic substrate-binding protein 987764 11728504 BSVBI22_A1017 Brucella suis VBI22 ABC transporter periplasmic substrate-binding protein YP_005154701.1 986769 D 1112912 CDS YP_005154702.1 376280696 11728505 987788..988390 1 NC_016797.1 identified by similarity to GP:15156733; match to protein family HMM PF03886; putative lipoprotein 988390 11728505 BSVBI22_A1018 Brucella suis VBI22 putative lipoprotein YP_005154702.1 987788 D 1112912 CDS YP_005154703.1 376280697 11728506 complement(988452..988559) 1 NC_016797.1 hypothetical protein 988559 11728506 BSVBI22_A1019 Brucella suis VBI22 hypothetical protein YP_005154703.1 988452 R 1112912 CDS YP_005154704.1 376280698 11728507 complement(988630..993303) 1 NC_016797.1 identified by similarity to GP:15074750; match to protein family HMM TIGR01369; match to protein family HMM TIGR01612; hypothetical protein 993303 11728507 BSVBI22_A1020 Brucella suis VBI22 hypothetical protein YP_005154704.1 988630 R 1112912 CDS YP_005154705.1 376280699 11728508 993518..993682 1 NC_016797.1 hypothetical protein 993682 11728508 BSVBI22_A1021 Brucella suis VBI22 hypothetical protein YP_005154705.1 993518 D 1112912 CDS YP_005154706.1 376280700 11728509 993918..994241 1 NC_016797.1 identified by similarity to EGAD:5699; match to protein family HMM PF00111; ferredoxin, 2Fe-2S 994241 11728509 BSVBI22_A1022 Brucella suis VBI22 ferredoxin, 2Fe-2S YP_005154706.1 993918 D 1112912 CDS YP_005154707.1 376280701 11728511 complement(994885..995505) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0625; hypothetical protein 995505 11728511 BSVBI22_A1024 Brucella suis VBI22 hypothetical protein YP_005154707.1 994885 R 1112912 CDS YP_005154708.1 376280702 11728512 995663..996502 1 NC_016797.1 identified by similarity to SP:P28822; match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 996502 folP 11728512 folP Brucella suis VBI22 dihydropteroate synthase YP_005154708.1 995663 D 1112912 CDS YP_005154709.1 376280703 11728513 996521..996880 1 NC_016797.1 identified by similarity to EGAD:14090; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; dihydroneopterin aldolase 996880 folB 11728513 folB Brucella suis VBI22 dihydroneopterin aldolase YP_005154709.1 996521 D 1112912 CDS YP_005154710.1 376280704 11728514 996877..997410 1 NC_016797.1 identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 997410 folK 11728514 folK Brucella suis VBI22 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_005154710.1 996877 D 1112912 CDS YP_005154711.1 376280705 11728515 complement(997525..998082) 1 NC_016797.1 identified by similarity to GP:14021684; hypothetical protein 998082 11728515 BSVBI22_A1028 Brucella suis VBI22 hypothetical protein YP_005154711.1 997525 R 1112912 CDS YP_005154712.1 376280706 11728516 complement(998334..999407) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0615; match to protein family HMM PF05128; match to protein family HMM TIGR01620; hypothetical protein 999407 11728516 BSVBI22_A1029 Brucella suis VBI22 hypothetical protein YP_005154712.1 998334 R 1112912 CDS YP_005154713.1 376280707 11728517 complement(999404..1000864) 1 NC_016797.1 identified by similarity to GP:14021682; match to protein family HMM PF04317; hypothetical protein 1000864 11728517 BSVBI22_A1030 Brucella suis VBI22 hypothetical protein YP_005154713.1 999404 R 1112912 CDS YP_005154714.1 376280708 11728518 complement(1000957..1001457) 1 NC_016797.1 identified by similarity to GP:14021681; hypothetical protein 1001457 11728518 BSVBI22_A1031 Brucella suis VBI22 hypothetical protein YP_005154714.1 1000957 R 1112912 CDS YP_005154715.1 376280709 11728519 1001854..1002270 1 NC_016797.1 identified by similarity to EGAD:19456; match to protein family HMM PF01258; dnaK suppressor protein 1002270 dksA 11728519 dksA Brucella suis VBI22 dnaK suppressor protein YP_005154715.1 1001854 D 1112912 CDS YP_005154716.1 376280710 11728520 1002280..1002375 1 NC_016797.1 hypothetical protein 1002375 11728520 BSVBI22_A1033 Brucella suis VBI22 hypothetical protein YP_005154716.1 1002280 D 1112912 CDS YP_005154717.1 376280711 11728521 complement(1002439..1003671) 1 NC_016797.1 hypothetical protein 1003671 11728521 BSVBI22_A1034 Brucella suis VBI22 hypothetical protein YP_005154717.1 1002439 R 1112912 CDS YP_005154718.1 376280712 11728522 1003897..1006734 1 NC_016797.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase/response regulator 1006734 11728522 BSVBI22_A1035 Brucella suis VBI22 sensory box histidine kinase/response regulator YP_005154718.1 1003897 D 1112912 CDS YP_005154719.1 376280713 11728523 1006759..1007967 1 NC_016797.1 identified by similarity to GP:15140178; match to protein family HMM PF03486; hypothetical protein 1007967 11728523 BSVBI22_A1036 Brucella suis VBI22 hypothetical protein YP_005154719.1 1006759 D 1112912 CDS YP_005154720.1 376280714 11728524 1007998..1009320 1 NC_016797.1 identified by match to protein family HMM PF00144; hypothetical protein 1009320 11728524 BSVBI22_A1037 Brucella suis VBI22 hypothetical protein YP_005154720.1 1007998 D 1112912 CDS YP_005154721.1 376280715 11728526 complement(1010628..1014422) 1 NC_016797.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1014422 11728526 BSVBI22_A1039 Brucella suis VBI22 ribonucleotide-diphosphate reductase subunit alpha YP_005154721.1 1010628 R 1112912 CDS YP_005154722.1 376280716 11728527 1014475..1014714 1 NC_016797.1 hypothetical protein 1014714 11728527 BSVBI22_A1040 Brucella suis VBI22 hypothetical protein YP_005154722.1 1014475 D 1112912 CDS YP_005154723.1 376280717 11728528 complement(1015124..1015612) 1 NC_016797.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 1015612 11728528 BSVBI22_A1041 Brucella suis VBI22 MutT/nudix family protein YP_005154723.1 1015124 R 1112912 CDS YP_005154724.1 376280718 11728529 complement(1015853..1016350) 1 NC_016797.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 1016350 11728529 BSVBI22_A1042 Brucella suis VBI22 xanthine-guanine phosphoribosyltransferase YP_005154724.1 1015853 R 1112912 CDS YP_005154725.1 376280719 11728530 complement(1016800..1017645) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0109; match to protein family HMM PF00582; hypothetical protein 1017645 11728530 BSVBI22_A1043 Brucella suis VBI22 hypothetical protein YP_005154725.1 1016800 R 1112912 CDS YP_005154726.1 376280720 11728531 complement(1017723..1018481) 1 NC_016797.1 identified by match to protein family HMM PF00994; cinA-related protein 1018481 11728531 BSVBI22_A1044 Brucella suis VBI22 cinA-related protein YP_005154726.1 1017723 R 1112912 CDS YP_005154727.1 376280721 11728532 1018642..1019241 1 NC_016797.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 1019241 wrbA 11728532 wrbA Brucella suis VBI22 TrpR binding protein WrbA YP_005154727.1 1018642 D 1112912 CDS YP_005154728.1 376280722 11728533 complement(1019219..1019368) 1 NC_016797.1 hypothetical protein 1019368 11728533 BSVBI22_A1046 Brucella suis VBI22 hypothetical protein YP_005154728.1 1019219 R 1112912 CDS YP_005154729.1 376280723 11728535 1019546..1020772 1 NC_016797.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 1020772 11728535 BSVBI22_A1047 Brucella suis VBI22 threonine dehydratase YP_005154729.1 1019546 D 1112912 CDS YP_005154730.1 376280724 11728536 1020867..1022474 1 NC_016797.1 identified by similarity to GP:14021336; match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD/DEAH box helicase 1022474 11728536 BSVBI22_A1048 Brucella suis VBI22 DEAD/DEAH box helicase YP_005154730.1 1020867 D 1112912 CDS YP_005154731.1 376280725 11728537 1022645..1023673 1 NC_016797.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 1023673 11728537 BSVBI22_A1049 Brucella suis VBI22 cysteine synthase A YP_005154731.1 1022645 D 1112912 CDS YP_005154732.1 376280726 11728538 1023676..1024419 1 NC_016797.1 identified by similarity to GP:15156264; hypothetical protein 1024419 11728538 BSVBI22_A1050 Brucella suis VBI22 hypothetical protein YP_005154732.1 1023676 D 1112912 CDS YP_005154733.1 376280727 11728539 1024446..1025300 1 NC_016797.1 identified by similarity to GP:15074554; match to protein family HMM PF00581; rhodanese family protein 1025300 11728539 BSVBI22_A1051 Brucella suis VBI22 rhodanese family protein YP_005154733.1 1024446 D 1112912 CDS YP_005154734.1 376280728 11728540 1025302..1025823 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 1025823 11728540 BSVBI22_A1052 Brucella suis VBI22 acetyltransferase YP_005154734.1 1025302 D 1112912 CDS YP_005154735.1 376280729 11728541 complement(1025862..1026656) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3729; match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1026656 11728541 BSVBI22_A1053 Brucella suis VBI22 diguanylate cyclase YP_005154735.1 1025862 R 1112912 CDS YP_005154736.1 376280730 11728542 complement(1027221..1028711) 1 NC_016797.1 identified by match to protein family HMM PF02550; acetyl-CoA hydrolase/transferase family protein 1028711 11728542 BSVBI22_A1054 Brucella suis VBI22 acetyl-CoA hydrolase/transferase family protein YP_005154736.1 1027221 R 1112912 CDS YP_005154737.1 376280731 11728543 complement(1028976..1030517) 1 NC_016797.1 identified by match to protein family HMM PF00083; match to protein family HMM TIGR00711; EmrB/QacA family drug resistance transporter 1030517 11728543 BSVBI22_A1055 Brucella suis VBI22 EmrB/QacA family drug resistance transporter YP_005154737.1 1028976 R 1112912 CDS YP_005154738.1 376280732 11728544 complement(1030517..1031617) 1 NC_016797.1 identified by match to protein family HMM PF00529; HlyD family secretion protein 1031617 11728544 BSVBI22_A1056 Brucella suis VBI22 HlyD family secretion protein YP_005154738.1 1030517 R 1112912 CDS YP_005154739.1 376280733 11728545 1032011..1032994 1 NC_016797.1 identified by similarity to SP:P42327; match to protein family HMM PF00107; zinc-containing alcohol dehydrogenase 1032994 11728545 BSVBI22_A1057 Brucella suis VBI22 zinc-containing alcohol dehydrogenase YP_005154739.1 1032011 D 1112912 CDS YP_005154740.1 376280734 11728546 complement(1033038..1034180) 1 NC_016797.1 identified by similarity to OMNI:NTL01XF00221; match to protein family HMM PF00557; proline dipeptidase 1034180 pepQ 11728546 pepQ Brucella suis VBI22 proline dipeptidase YP_005154740.1 1033038 R 1112912 CDS YP_005154741.1 376280735 11728547 complement(1034439..1035269) 1 NC_016797.1 identified by similarity to GP:15157001; match to protein family HMM PF00515; hypothetical protein 1035269 11728547 BSVBI22_A1059 Brucella suis VBI22 hypothetical protein YP_005154741.1 1034439 R 1112912 CDS YP_005154742.1 376280736 11728548 complement(1035378..1036343) 1 NC_016797.1 identified by similarity to GP:2708271; match to protein family HMM PF01758; sodium/bile acid symporter family protein 1036343 11728548 BSVBI22_A1060 Brucella suis VBI22 sodium/bile acid symporter family protein YP_005154742.1 1035378 R 1112912 CDS YP_005154743.1 376280737 11728549 complement(1036371..1036523) 1 NC_016797.1 hypothetical protein 1036523 11728549 BSVBI22_A1061 Brucella suis VBI22 hypothetical protein YP_005154743.1 1036371 R 1112912 CDS YP_005154744.1 376280738 11728550 complement(1036472..1037479) 1 NC_016797.1 identified by similarity to EGAD:45971; match to protein family HMM PF01370; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase 1037479 galE-1 11728550 galE-1 Brucella suis VBI22 UDP-glucose 4-epimerase YP_005154744.1 1036472 R 1112912 CDS YP_005154745.1 376280739 11728551 1037624..1038448 1 NC_016797.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 1038448 mazG 11728551 mazG Brucella suis VBI22 nucleoside triphosphate pyrophosphohydrolase YP_005154745.1 1037624 D 1112912 CDS YP_005154746.1 376280740 11728552 complement(1038457..1039068) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0717; hypothetical protein 1039068 11728552 BSVBI22_A1064 Brucella suis VBI22 hypothetical protein YP_005154746.1 1038457 R 1112912 CDS YP_005154747.1 376280741 11728553 complement(1039111..1039695) 1 NC_016797.1 identified by match to protein family HMM PF00881; nitroreductase family protein 1039695 11728553 BSVBI22_A1065 Brucella suis VBI22 nitroreductase family protein YP_005154747.1 1039111 R 1112912 CDS YP_005154748.1 376280742 11728554 1039933..1040925 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0719; hypothetical protein 1040925 11728554 BSVBI22_A1066 Brucella suis VBI22 hypothetical protein YP_005154748.1 1039933 D 1112912 CDS YP_005154749.1 376280743 11728555 complement(1040980..1042956) 1 NC_016797.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1042956 thrS 11728555 thrS Brucella suis VBI22 threonyl-tRNA synthetase YP_005154749.1 1040980 R 1112912 CDS YP_005154750.1 376280744 11728556 complement(1043171..1044403) 1 NC_016797.1 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 1044403 11728556 BSVBI22_A1068 Brucella suis VBI22 D-alanyl-D-alanine carboxypeptidase YP_005154750.1 1043171 R 1112912 CDS YP_005154751.1 376280745 11728557 complement(1044510..1044881) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0724; match to protein family HMM PF01809; match to protein family HMM TIGR00278; hypothetical protein 1044881 11728557 BSVBI22_A1069 Brucella suis VBI22 hypothetical protein YP_005154751.1 1044510 R 1112912 CDS YP_005154752.1 376280746 11728558 complement(1044883..1045323) 1 NC_016797.1 identified by match to protein family HMM PF01592; NifU-like protein 1045323 11728558 BSVBI22_A1070 Brucella suis VBI22 NifU-like protein YP_005154752.1 1044883 R 1112912 CDS YP_005154753.1 376280747 11728559 1045587..1046228 1 NC_016797.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1046228 folE 11728559 folE Brucella suis VBI22 GTP cyclohydrolase I YP_005154753.1 1045587 D 1112912 CDS YP_005154754.1 376280748 11728560 1046251..1046670 1 NC_016797.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 1046670 hisI 11728560 hisI Brucella suis VBI22 phosphoribosyl-AMP cyclohydrolase YP_005154754.1 1046251 D 1112912 CDS YP_005154755.1 376280749 11728561 1046887..1047834 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0729; match to protein family HMM PF01734; hypothetical protein 1047834 11728561 BSVBI22_A1073 Brucella suis VBI22 hypothetical protein YP_005154755.1 1046887 D 1112912 CDS YP_005154756.1 376280750 11728563 1048308..1049552 1 NC_016797.1 identified by match to protein family HMM PF00589; phage integrase family site specific recombinase 1049552 11728563 BSVBI22_A1074 Brucella suis VBI22 phage integrase family site specific recombinase YP_005154756.1 1048308 D 1112912 CDS YP_005154757.1 376280751 11728564 1049691..1050095 1 NC_016797.1 hypothetical protein 1050095 11728564 BSVBI22_A1075 Brucella suis VBI22 hypothetical protein YP_005154757.1 1049691 D 1112912 CDS YP_005154758.1 376280752 11728565 complement(1051012..1051191) 1 NC_016797.1 hypothetical protein 1051191 11728565 BSVBI22_A1076 Brucella suis VBI22 hypothetical protein YP_005154758.1 1051012 R 1112912 CDS YP_005154759.1 376280753 11728566 complement(1051779..1053143) 1 NC_016797.1 hypothetical protein 1053143 11728566 BSVBI22_A1077 Brucella suis VBI22 hypothetical protein YP_005154759.1 1051779 R 1112912 CDS YP_005154760.1 376280754 11728567 complement(1053701..1054318) 1 NC_016797.1 identified by match to protein family HMM PF00239; resolvase family site-specific recombinase 1054318 11728567 BSVBI22_A1078 Brucella suis VBI22 resolvase family site-specific recombinase YP_005154760.1 1053701 R 1112912 CDS YP_005154761.1 376280755 11728568 complement(1055117..1055521) 1 NC_016797.1 identified by match to protein family HMM PF02498; BRO family protein 1055521 11728568 BSVBI22_A1079 Brucella suis VBI22 BRO family protein YP_005154761.1 1055117 R 1112912 CDS YP_005154762.1 376280756 11728570 complement(1056108..1057253) 1 NC_016797.1 identified by match to protein family HMM PF02515; CAIB/BAIF family protein 1057253 11728570 BSVBI22_A1080 Brucella suis VBI22 CAIB/BAIF family protein YP_005154762.1 1056108 R 1112912 CDS YP_005154763.1 376280757 11728571 complement(1057332..1058516) 1 NC_016797.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; glutaryl-CoA dehydrogenase 1058516 11728571 BSVBI22_A1081 Brucella suis VBI22 glutaryl-CoA dehydrogenase YP_005154763.1 1057332 R 1112912 CDS YP_005154764.1 376280758 11728572 1058618..1059550 1 NC_016797.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1059550 11728572 BSVBI22_A1082 Brucella suis VBI22 LysR family transcriptional regulator YP_005154764.1 1058618 D 1112912 CDS YP_005154765.1 376280759 11728573 complement(1059520..1060503) 1 NC_016797.1 identified by match to protein family HMM PF00296; luciferase family protein 1060503 11728573 BSVBI22_A1083 Brucella suis VBI22 luciferase family protein YP_005154765.1 1059520 R 1112912 CDS YP_005154766.1 376280760 11728574 complement(1060584..1063673) 1 NC_016797.1 identified by match to protein family HMM PF00873; AcrB/AcrD/AcrF multidrug efflux protein 1063673 11728574 BSVBI22_A1084 Brucella suis VBI22 AcrB/AcrD/AcrF multidrug efflux protein YP_005154766.1 1060584 R 1112912 CDS YP_005154767.1 376280761 11728575 complement(1063683..1064831) 1 NC_016797.1 identified by similarity to OMNI:VC0165; match to protein family HMM TIGR01730; hypothetical protein 1064831 11728575 BSVBI22_A1085 Brucella suis VBI22 hypothetical protein YP_005154767.1 1063683 R 1112912 CDS YP_005154768.1 376280762 11728576 1064972..1065538 1 NC_016797.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1065538 11728576 BSVBI22_A1086 Brucella suis VBI22 TetR family transcriptional regulator YP_005154768.1 1064972 D 1112912 CDS YP_005154769.1 376280763 11728577 complement(1065575..1066708) 1 NC_016797.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1066708 tgt 11728577 tgt Brucella suis VBI22 queuine tRNA-ribosyltransferase YP_005154769.1 1065575 R 1112912 CDS YP_005154770.1 376280764 11728578 complement(1066705..1067796) 1 NC_016797.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1067796 queA 11728578 queA Brucella suis VBI22 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_005154770.1 1066705 R 1112912 CDS YP_005154771.1 376280765 11728579 complement(1067918..1068424) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0580; match to protein family HMM PF00160; cyclophilin type peptidyl-prolyl cis-trans isomerase 1068424 11728579 BSVBI22_A1089 Brucella suis VBI22 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_005154771.1 1067918 R 1112912 CDS YP_005154772.1 376280766 11728580 complement(1068487..1069077) 1 NC_016797.1 identified by similarity to OMNI:CC1584; match to protein family HMM PF00160; cyclophilin type peptidyl-prolyl cis-trans isomerase 1069077 11728580 BSVBI22_A1090 Brucella suis VBI22 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_005154772.1 1068487 R 1112912 CDS YP_005154773.1 376280767 11728581 complement(1069098..1069592) 1 NC_016797.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1069592 coaD 11728581 coaD Brucella suis VBI22 phosphopantetheine adenylyltransferase YP_005154773.1 1069098 R 1112912 CDS YP_005154774.1 376280768 11728582 complement(1069808..1070047) 1 NC_016797.1 hypothetical protein 1070047 11728582 BSVBI22_A1092 Brucella suis VBI22 hypothetical protein YP_005154774.1 1069808 R 1112912 CDS YP_005154775.1 376280769 11728583 complement(1070103..1072871) 1 NC_016797.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1072871 gyrA 11728583 gyrA Brucella suis VBI22 DNA gyrase subunit A YP_005154775.1 1070103 R 1112912 CDS YP_005154776.1 376280770 11728584 1073159..1073788 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0590; match to protein family HMM PF01914; match to protein family HMM TIGR00427; hypothetical protein 1073788 11728584 BSVBI22_A1094 Brucella suis VBI22 hypothetical protein YP_005154776.1 1073159 D 1112912 CDS YP_005154777.1 376280771 11728585 complement(1073879..1074457) 1 NC_016797.1 guanylate kinase 1074457 11728585 BSVBI22_A1095 Brucella suis VBI22 guanylate kinase YP_005154777.1 1073879 R 1112912 CDS YP_005154778.1 376280772 11728586 1074644..1075405 1 NC_016797.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1075405 11728586 BSVBI22_A1096 Brucella suis VBI22 GntR family transcriptional regulator YP_005154778.1 1074644 D 1112912 CDS YP_005154779.1 376280773 11728587 1075756..1075896 1 NC_016797.1 hypothetical protein 1075896 11728587 BSVBI22_A1097 Brucella suis VBI22 hypothetical protein YP_005154779.1 1075756 D 1112912 CDS YP_005154780.1 376280774 11728588 complement(1076090..1076596) 1 NC_016797.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; ssDNA-binding protein 1076596 11728588 BSVBI22_A1098 Brucella suis VBI22 ssDNA-binding protein YP_005154780.1 1076090 R 1112912 CDS YP_005154781.1 376280775 11728589 1077164..1077364 1 NC_016797.1 hypothetical protein 1077364 11728589 BSVBI22_A1099 Brucella suis VBI22 hypothetical protein YP_005154781.1 1077164 D 1112912 CDS YP_005154782.1 376280776 11728590 1077495..1080419 1 NC_016797.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1080419 uvrA 11728590 uvrA Brucella suis VBI22 excinuclease ABC subunit A YP_005154782.1 1077495 D 1112912 CDS YP_005154783.1 376280777 11728591 complement(1080605..1080880) 1 NC_016797.1 identified by similarity to EGAD:8582; match to protein family HMM PF00216; DNA-binding protein HU 1080880 11728591 BSVBI22_A1101 Brucella suis VBI22 DNA-binding protein HU YP_005154783.1 1080605 R 1112912 CDS YP_005154784.1 376280778 11728592 complement(1081061..1083499) 1 NC_016797.1 identified by similarity to EGAD:18728; match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM TIGR00763; ATP-dependent protease La 1083499 lon 11728592 lon Brucella suis VBI22 ATP-dependent protease La YP_005154784.1 1081061 R 1112912 CDS YP_005154785.1 376280779 11728593 1083820..1083939 1 NC_016797.1 hypothetical protein 1083939 11728593 BSVBI22_A1103 Brucella suis VBI22 hypothetical protein YP_005154785.1 1083820 D 1112912 CDS YP_005154786.1 376280780 11728594 complement(1083931..1085205) 1 NC_016797.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1085205 clpX 11728594 clpX Brucella suis VBI22 ATP-dependent protease ATP-binding subunit ClpX YP_005154786.1 1083931 R 1112912 CDS YP_005154787.1 376280781 11728595 complement(1085587..1086216) 1 NC_016797.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1086216 clpP 11728595 clpP Brucella suis VBI22 ATP-dependent Clp protease proteolytic subunit YP_005154787.1 1085587 R 1112912 CDS YP_005154788.1 376280782 11728596 complement(1086321..1087739) 1 NC_016797.1 GTP-binding protein 1087739 11728596 BSVBI22_A1106 Brucella suis VBI22 GTP-binding protein YP_005154788.1 1086321 R 1112912 CDS YP_005154789.1 376280783 11728597 complement(1087930..1088166) 1 NC_016797.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 1088166 hfq 11728597 hfq Brucella suis VBI22 RNA-binding protein Hfq YP_005154789.1 1087930 R 1112912 CDS YP_005154790.1 376280784 11728598 complement(1088172..1088411) 1 NC_016797.1 hypothetical protein 1088411 11728598 BSVBI22_A1108 Brucella suis VBI22 hypothetical protein YP_005154790.1 1088172 R 1112912 CDS YP_005154791.1 376280785 11728599 complement(1088395..1089225) 1 NC_016797.1 hypothetical protein 1089225 11728599 BSVBI22_A1109 Brucella suis VBI22 hypothetical protein YP_005154791.1 1088395 R 1112912 CDS YP_005154792.1 376280786 11728600 complement(1089274..1090650) 1 NC_016797.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 1090650 trkA 11728600 trkA Brucella suis VBI22 potassium transporter peripheral membrane protein YP_005154792.1 1089274 R 1112912 CDS YP_005154793.1 376280787 11728601 complement(1090675..1092036) 1 NC_016797.1 identified by similarity to EGAD:5624; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199; nitrogen regulation protein NtrX 1092036 ntrX 11728601 ntrX Brucella suis VBI22 nitrogen regulation protein NtrX YP_005154793.1 1090675 R 1112912 CDS YP_005154794.1 376280788 11728602 complement(1092038..1094362) 1 NC_016797.1 identified by similarity to EGAD:10502; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR00229; nitrogen regulation protein NtrY 1094362 ntrY 11728602 ntrY Brucella suis VBI22 nitrogen regulation protein NtrY YP_005154794.1 1092038 R 1112912 CDS YP_005154795.1 376280789 11728603 complement(1094453..1095928) 1 NC_016797.1 identified by similarity to EGAD:19665; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199; match to protein family HMM TIGR01818; nitrogen regulation protein NtrC 1095928 ntrC 11728603 ntrC Brucella suis VBI22 nitrogen regulation protein NtrC YP_005154795.1 1094453 R 1112912 CDS YP_005154796.1 376280790 11728604 complement(1095925..1097028) 1 NC_016797.1 identified by similarity to EGAD:22187; match to protein family HMM PF00512; match to protein family HMM PF02518; nitrogen regulation protein NtrB 1097028 ntrB 11728604 ntrB Brucella suis VBI22 nitrogen regulation protein NtrB YP_005154796.1 1095925 R 1112912 CDS YP_005154797.1 376280791 11728605 complement(1097067..1098068) 1 NC_016797.1 identified by similarity to EGAD:30550; match to protein family HMM PF01207; match to protein family HMM TIGR00737; nitrogen regulation protein Nifr3 1098068 nifR3 11728605 nifR3 Brucella suis VBI22 nitrogen regulation protein Nifr3 YP_005154797.1 1097067 R 1112912 CDS YP_005154798.1 376280792 11728606 1098206..1099435 1 NC_016797.1 bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1099435 ispDF 11728606 ispDF Brucella suis VBI22 bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_005154798.1 1098206 D 1112912 CDS YP_005154799.1 376280793 11728607 1099432..1099929 1 NC_016797.1 identified by similarity to GP:15074388; match to protein family HMM PF02464; match to protein family HMM TIGR00199; competence/damage-inducible protein CinA 1099929 cinA 11728607 cinA Brucella suis VBI22 competence/damage-inducible protein CinA YP_005154799.1 1099432 D 1112912 CDS YP_005154800.1 376280794 11728608 1100006..1100746 1 NC_016797.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 1100746 11728608 BSVBI22_A1118 Brucella suis VBI22 short chain dehydrogenase/reductase family oxidoreductase YP_005154800.1 1100006 D 1112912 CDS YP_005154801.1 376280795 11728609 complement(1100804..1101214) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0302; match to protein family HMM PF03654; hypothetical protein 1101214 11728609 BSVBI22_A1119 Brucella suis VBI22 hypothetical protein YP_005154801.1 1100804 R 1112912 CDS YP_005154802.1 376280796 11728610 complement(1101268..1102236) 1 NC_016797.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1102236 lipA 11728610 lipA Brucella suis VBI22 lipoyl synthase YP_005154802.1 1101268 R 1112912 CDS YP_005154803.1 376280797 11728611 complement(1102346..1102507) 1 NC_016797.1 hypothetical protein 1102507 11728611 BSVBI22_A1121 Brucella suis VBI22 hypothetical protein YP_005154803.1 1102346 R 1112912 CDS YP_005154804.1 376280798 11728612 complement(1102626..1104089) 1 NC_016797.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1104089 lpdA-1 11728612 lpdA-1 Brucella suis VBI22 dihydrolipoamide dehydrogenase YP_005154804.1 1102626 R 1112912 CDS YP_005154805.1 376280799 11728613 complement(1104172..1105515) 1 NC_016797.1 identified by similarity to SP:Q9R9N3; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM TIGR01349; branched-chain alpha-keto acid dehydrogenase subunit E2 1105515 aceF 11728613 aceF Brucella suis VBI22 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_005154805.1 1104172 R 1112912 CDS YP_005154806.1 376280800 11728614 complement(1105533..1106918) 1 NC_016797.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 1106918 pdhB 11728614 pdhB Brucella suis VBI22 pyruvate dehydrogenase subunit beta YP_005154806.1 1105533 R 1112912 CDS YP_005154807.1 376280801 11728615 complement(1106937..1107977) 1 NC_016797.1 identified by similarity to SP:Q9R9N5; match to protein family HMM PF00676; pyruvate dehydrogenase complex, E1 component subunit alpha 1107977 pdhA 11728615 pdhA Brucella suis VBI22 pyruvate dehydrogenase complex, E1 component subunit alpha YP_005154807.1 1106937 R 1112912 CDS YP_005154808.1 376280802 11728616 complement(1108116..1108445) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0293; match to protein family HMM PF04977; hypothetical protein 1108445 11728616 BSVBI22_A1126 Brucella suis VBI22 hypothetical protein YP_005154808.1 1108116 R 1112912 CDS YP_005154809.1 376280803 11728617 complement(1108717..1109298) 1 NC_016797.1 identified by similarity to OMNI:CC1925; hypothetical protein 1109298 11728617 BSVBI22_A1127 Brucella suis VBI22 hypothetical protein YP_005154809.1 1108717 R 1112912 CDS YP_005154810.1 376280804 11728618 complement(1109635..1110912) 1 NC_016797.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1110912 eno 11728618 eno Brucella suis VBI22 phosphopyruvate hydratase YP_005154810.1 1109635 R 1112912 CDS YP_005154811.1 376280805 11728619 complement(1111099..1111932) 1 NC_016797.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1111932 kdsA 11728619 kdsA Brucella suis VBI22 2-dehydro-3-deoxyphosphooctonate aldolase YP_005154811.1 1111099 R 1112912 CDS YP_005154812.1 376280806 11728620 complement(1112038..1113666) 1 NC_016797.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1113666 pyrG 11728620 pyrG Brucella suis VBI22 CTP synthetase YP_005154812.1 1112038 R 1112912 CDS YP_005154813.1 376280807 11728621 complement(1113679..1113801) 1 NC_016797.1 hypothetical protein 1113801 11728621 BSVBI22_A1131 Brucella suis VBI22 hypothetical protein YP_005154813.1 1113679 R 1112912 CDS YP_005154814.1 376280808 11728622 complement(1113936..1114649) 1 NC_016797.1 identified by similarity to GP:15157507; match to protein family HMM PF03734; hypothetical protein 1114649 11728622 BSVBI22_A1132 Brucella suis VBI22 hypothetical protein YP_005154814.1 1113936 R 1112912 CDS YP_005154815.1 376280809 11728623 complement(1114882..1115328) 1 NC_016797.1 identified by match to protein family HMM PF03840; preprotein translocase subunit SecG 1115328 secG 11728623 secG Brucella suis VBI22 preprotein translocase subunit SecG YP_005154815.1 1114882 R 1112912 CDS YP_005154816.1 376280810 11728624 complement(1115428..1116192) 1 NC_016797.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1116192 tpiA 11728624 tpiA Brucella suis VBI22 triosephosphate isomerase YP_005154816.1 1115428 R 1112912 CDS YP_005154817.1 376280811 11728625 1116411..1118297 1 NC_016797.1 rotamase family protein 1118297 11728625 BSVBI22_A1135 Brucella suis VBI22 rotamase family protein YP_005154817.1 1116411 D 1112912 CDS YP_005154818.1 376280812 11728626 1118312..1119331 1 NC_016797.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1119331 trpD 11728626 trpD Brucella suis VBI22 anthranilate phosphoribosyltransferase YP_005154818.1 1118312 D 1112912 CDS YP_005154819.1 376280813 11728627 1119348..1120154 1 NC_016797.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; Indole-3-glycerol phosphate synthase 1120154 trpC 11728627 trpC Brucella suis VBI22 Indole-3-glycerol phosphate synthase YP_005154819.1 1119348 D 1112912 CDS YP_005154820.1 376280814 11728628 1120151..1120648 1 NC_016797.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein C 1120648 moaC 11728628 moaC Brucella suis VBI22 molybdenum cofactor biosynthesis protein C YP_005154820.1 1120151 D 1112912 CDS YP_005154821.1 376280815 11728629 1120744..1121958 1 NC_016797.1 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177; molybdopterin biosynthesis protein MoeA 1121958 moeA 11728629 moeA Brucella suis VBI22 molybdopterin biosynthesis protein MoeA YP_005154821.1 1120744 D 1112912 CDS YP_005154822.1 376280816 11728630 1122206..1122928 1 NC_016797.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 1122928 lexA 11728630 lexA Brucella suis VBI22 LexA repressor YP_005154822.1 1122206 D 1112912 CDS YP_005154823.1 376280817 11728631 complement(1122922..1125453) 1 NC_016797.1 identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; ComEC/Rec2 family protein 1125453 11728631 BSVBI22_A1141 Brucella suis VBI22 ComEC/Rec2 family protein YP_005154823.1 1122922 R 1112912 CDS YP_005154824.1 376280818 11728632 complement(1125485..1125661) 1 NC_016797.1 hypothetical protein 1125661 11728632 BSVBI22_A1142 Brucella suis VBI22 hypothetical protein YP_005154824.1 1125485 R 1112912 CDS YP_005154825.1 376280819 11728633 1125674..1127095 1 NC_016797.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1127095 gltX 11728633 gltX Brucella suis VBI22 glutamyl-tRNA synthetase YP_005154825.1 1125674 D 1112912 CDS YP_005154826.1 376280820 11728634 1127324..1128616 1 NC_016797.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 1128616 gltA 11728634 gltA Brucella suis VBI22 type II citrate synthase YP_005154826.1 1127324 D 1112912 CDS YP_005154827.1 376280821 11728635 complement(1128789..1129976) 1 NC_016797.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 1129976 lpxB 11728635 lpxB Brucella suis VBI22 lipid-A-disaccharide synthase YP_005154827.1 1128789 R 1112912 CDS YP_005154828.1 376280822 11728636 complement(1129973..1130875) 1 NC_016797.1 identified by similarity to GP:15074439; hypothetical protein 1130875 11728636 BSVBI22_A1146 Brucella suis VBI22 hypothetical protein YP_005154828.1 1129973 R 1112912 CDS YP_005154829.1 376280823 11728637 complement(1130856..1131692) 1 NC_016797.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 1131692 lpxA 11728637 lpxA Brucella suis VBI22 UDP-N-acetylglucosamine acyltransferase YP_005154829.1 1130856 R 1112912 CDS YP_005154830.1 376280824 11728638 complement(1131701..1132174) 1 NC_016797.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1132174 fabZ 11728638 fabZ Brucella suis VBI22 (3R)-hydroxymyristoyl-ACP dehydratase YP_005154830.1 1131701 R 1112912 CDS YP_005154831.1 376280825 11728639 complement(1132167..1133222) 1 NC_016797.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1133222 lpxD 11728639 lpxD Brucella suis VBI22 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_005154831.1 1132167 R 1112912 CDS YP_005154832.1 376280826 11728640 complement(1133276..1135621) 1 NC_016797.1 identified by match to protein family HMM PF01103; surface antigen 1135621 11728640 BSVBI22_A1150 Brucella suis VBI22 surface antigen YP_005154832.1 1133276 R 1112912 CDS YP_005154833.1 376280827 11728641 complement(1135605..1135724) 1 NC_016797.1 hypothetical protein 1135724 11728641 BSVBI22_A1151 Brucella suis VBI22 hypothetical protein YP_005154833.1 1135605 R 1112912 CDS YP_005154834.1 376280828 11728642 complement(1135957..1137096) 1 NC_016797.1 identified by match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054; membrane-associated zinc metalloprotease 1137096 11728642 BSVBI22_A1152 Brucella suis VBI22 membrane-associated zinc metalloprotease YP_005154834.1 1135957 R 1112912 CDS YP_005154835.1 376280829 11728643 complement(1137163..1137975) 1 NC_016797.1 identified by similarity to EGAD:108469; match to protein family HMM PF01148; phosphatidate cytidylyltransferase 1137975 cdsA 11728643 cdsA Brucella suis VBI22 phosphatidate cytidylyltransferase YP_005154835.1 1137163 R 1112912 CDS YP_005154836.1 376280830 11728644 complement(1138080..1138844) 1 NC_016797.1 identified by match to protein family HMM PF01255; match to protein family HMM TIGR00055; undecaprenyl diphosphate synthase 1138844 uppS 11728644 uppS Brucella suis VBI22 undecaprenyl diphosphate synthase YP_005154836.1 1138080 R 1112912 CDS YP_005154837.1 376280831 11728645 complement(1138889..1139449) 1 NC_016797.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1139449 frr 11728645 frr Brucella suis VBI22 ribosome recycling factor YP_005154837.1 1138889 R 1112912 CDS YP_005154838.1 376280832 11728646 complement(1139485..1140207) 1 NC_016797.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1140207 pyrH 11728646 pyrH Brucella suis VBI22 uridylate kinase YP_005154838.1 1139485 R 1112912 CDS YP_005154839.1 376280833 11728647 complement(1140374..1141291) 1 NC_016797.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1141291 tsf 11728647 tsf Brucella suis VBI22 elongation factor Ts YP_005154839.1 1140374 R 1112912 CDS YP_005154840.1 376280834 11728648 complement(1141481..1142251) 1 NC_016797.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1142251 rpsB 11728648 rpsB Brucella suis VBI22 30S ribosomal protein S2 YP_005154840.1 1141481 R 1112912 CDS YP_005154841.1 376280835 11728649 complement(1142474..1142968) 1 NC_016797.1 identified by similarity to GP:9107039; hypothetical protein 1142968 11728649 BSVBI22_A1159 Brucella suis VBI22 hypothetical protein YP_005154841.1 1142474 R 1112912 CDS YP_005154842.1 376280836 11728650 complement(1143081..1143923) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0524; hypothetical protein 1143923 11728650 BSVBI22_A1160 Brucella suis VBI22 hypothetical protein YP_005154842.1 1143081 R 1112912 CDS YP_005154843.1 376280837 11728651 1144067..1144531 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0525; match to protein family HMM PF01042; hypothetical protein 1144531 11728651 BSVBI22_A1161 Brucella suis VBI22 hypothetical protein YP_005154843.1 1144067 D 1112912 CDS YP_005154844.1 376280838 11728652 1144533..1145273 1 NC_016797.1 identified by similarity to EGAD:9938; match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase family protein 1145273 11728652 BSVBI22_A1162 Brucella suis VBI22 glycerophosphoryl diester phosphodiesterase family protein YP_005154844.1 1144533 D 1112912 CDS YP_005154845.1 376280839 11728653 1145328..1146515 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0527; match to protein family HMM PF04339; hypothetical protein 1146515 11728653 BSVBI22_A1163 Brucella suis VBI22 hypothetical protein YP_005154845.1 1145328 D 1112912 CDS YP_005154846.1 376280840 11728654 1146587..1147009 1 NC_016797.1 identified by match to protein family HMM PF01230; HIT family protein 1147009 11728654 BSVBI22_A1164 Brucella suis VBI22 HIT family protein YP_005154846.1 1146587 D 1112912 CDS YP_005154847.1 376280841 11728655 complement(1147116..1149590) 1 NC_016797.1 identified by similarity to EGAD:17776; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM TIGR01967; ATP-dependent Clp protease, ATP-binding subunit ClpA 1149590 clpA 11728655 clpA Brucella suis VBI22 ATP-dependent Clp protease, ATP-binding subunit ClpA YP_005154847.1 1147116 R 1112912 CDS YP_005154848.1 376280842 11728656 complement(1149597..1150007) 1 NC_016797.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1150007 clpS 11728656 clpS Brucella suis VBI22 ATP-dependent Clp protease adaptor protein ClpS YP_005154848.1 1149597 R 1112912 CDS YP_005154849.1 376280843 11728657 1150008..1150199 1 NC_016797.1 hypothetical protein 1150199 11728657 BSVBI22_A1167 Brucella suis VBI22 hypothetical protein YP_005154849.1 1150008 D 1112912 CDS YP_005154850.1 376280844 11728658 1150433..1151851 1 NC_016797.1 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 1151851 11728658 BSVBI22_A1168 Brucella suis VBI22 D-alanyl-D-alanine carboxypeptidase YP_005154850.1 1150433 D 1112912 CDS YP_005154851.1 376280845 11728659 1151883..1152224 1 NC_016797.1 identified by similarity to GP:15074343; hypothetical protein 1152224 11728659 BSVBI22_A1169 Brucella suis VBI22 hypothetical protein YP_005154851.1 1151883 D 1112912 CDS YP_005154852.1 376280846 11728660 complement(1152338..1152775) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0534; hypothetical protein 1152775 11728660 BSVBI22_A1170 Brucella suis VBI22 hypothetical protein YP_005154852.1 1152338 R 1112912 CDS YP_005154853.1 376280847 11728661 complement(1152864..1154267) 1 NC_016797.1 identified by similarity to SP:P42630; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; iron-sulfur-dependent L-serine dehydratase 1154267 sda 11728661 sda Brucella suis VBI22 iron-sulfur-dependent L-serine dehydratase YP_005154853.1 1152864 R 1112912 CDS YP_005154854.1 376280848 11728662 complement(1154465..1154590) 1 NC_016797.1 hypothetical protein 1154590 11728662 BSVBI22_A1172 Brucella suis VBI22 hypothetical protein YP_005154854.1 1154465 R 1112912 CDS YP_005154855.1 376280849 11728663 complement(1154789..1155595) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0537; match to protein family HMM PF02698; hypothetical protein 1155595 11728663 BSVBI22_A1173 Brucella suis VBI22 hypothetical protein YP_005154855.1 1154789 R 1112912 CDS YP_005154856.1 376280850 11728664 1155758..1156744 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1038; hypothetical protein 1156744 11728664 BSVBI22_A1174 Brucella suis VBI22 hypothetical protein YP_005154856.1 1155758 D 1112912 CDS YP_005154857.1 376280851 11728665 complement(1156755..1157141) 1 NC_016797.1 identified by match to protein family HMM PF00376; transcriptional regulator 1157141 11728665 BSVBI22_A1175 Brucella suis VBI22 transcriptional regulator YP_005154857.1 1156755 R 1112912 CDS YP_005154858.1 376280852 11728666 1157379..1157744 1 NC_016797.1 hypothetical protein 1157744 11728666 BSVBI22_A1176 Brucella suis VBI22 hypothetical protein YP_005154858.1 1157379 D 1112912 CDS YP_005154859.1 376280853 11728667 1157759..1158106 1 NC_016797.1 identified by similarity to GP:15141218; hypothetical protein 1158106 11728667 BSVBI22_A1177 Brucella suis VBI22 hypothetical protein YP_005154859.1 1157759 D 1112912 CDS YP_005154860.1 376280854 11728668 1158177..1158491 1 NC_016797.1 identified by similarity to GP:15156035; hypothetical protein 1158491 11728668 BSVBI22_A1178 Brucella suis VBI22 hypothetical protein YP_005154860.1 1158177 D 1112912 CDS YP_005154861.1 376280855 11728669 1158936..1159403 1 NC_016797.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1159403 11728669 BSVBI22_A1179 Brucella suis VBI22 7-cyano-7-deazaguanine reductase YP_005154861.1 1158936 D 1112912 CDS YP_005154862.1 376280856 11728670 complement(1159407..1159556) 1 NC_016797.1 hypothetical protein 1159556 11728670 BSVBI22_A1180 Brucella suis VBI22 hypothetical protein YP_005154862.1 1159407 R 1112912 CDS YP_005154863.1 376280857 11728671 1159534..1159710 1 NC_016797.1 hypothetical protein 1159710 11728671 BSVBI22_A1181 Brucella suis VBI22 hypothetical protein YP_005154863.1 1159534 D 1112912 CDS YP_005154864.1 376280858 11728672 1159742..1160284 1 NC_016797.1 identified by similarity to OMNI:CC2122; hypothetical protein 1160284 11728672 BSVBI22_A1182 Brucella suis VBI22 hypothetical protein YP_005154864.1 1159742 D 1112912 CDS YP_005154865.1 376280859 11728673 complement(1160287..1161699) 1 NC_016797.1 identified by similarity to GP:15159740; match to protein family HMM PF01381; Cro/CI family transcriptional regulator 1161699 11728673 BSVBI22_A1183 Brucella suis VBI22 Cro/CI family transcriptional regulator YP_005154865.1 1160287 R 1112912 CDS YP_005154866.1 376280860 11728675 1162703..1164706 1 NC_016797.1 identified by similarity to EGAD:2033; match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786; propionyl-CoA carboxylase subunit alpha 1164706 pccA 11728675 pccA Brucella suis VBI22 propionyl-CoA carboxylase subunit alpha YP_005154866.1 1162703 D 1112912 CDS YP_005154867.1 376280861 11728676 1164767..1166905 1 NC_016797.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 1166905 bhbA 11728676 bhbA Brucella suis VBI22 methylmalonyl-CoA mutase YP_005154867.1 1164767 D 1112912 CDS YP_005154868.1 376280862 11728677 complement(1167012..1167443) 1 NC_016797.1 identified by similarity to GP:15140764; hypothetical protein 1167443 11728677 BSVBI22_A1187 Brucella suis VBI22 hypothetical protein YP_005154868.1 1167012 R 1112912 CDS YP_005154869.1 376280863 11728678 complement(1167561..1169609) 1 NC_016797.1 identified by similarity to OMNI:NTL01BH2941; match to protein family HMM TIGR02123; hypothetical protein 1169609 11728678 BSVBI22_A1188 Brucella suis VBI22 hypothetical protein YP_005154869.1 1167561 R 1112912 CDS YP_005154870.1 376280864 11728679 complement(1169650..1169802) 1 NC_016797.1 hypothetical protein 1169802 11728679 BSVBI22_A1189 Brucella suis VBI22 hypothetical protein YP_005154870.1 1169650 R 1112912 CDS YP_005154871.1 376280865 11728680 complement(1169846..1170835) 1 NC_016797.1 identified by similarity to EGAD:7185; match to protein family HMM TIGR02122; TRAP transporter solute receptor TAXI family protein 1170835 11728680 BSVBI22_A1190 Brucella suis VBI22 TRAP transporter solute receptor TAXI family protein YP_005154871.1 1169846 R 1112912 CDS YP_005154872.1 376280866 11728681 complement(1170981..1171814) 1 NC_016797.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1171814 murI 11728681 murI Brucella suis VBI22 glutamate racemase YP_005154872.1 1170981 R 1112912 CDS YP_005154873.1 376280867 11728682 complement(1171811..1172641) 1 NC_016797.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050; RNA methyltransferase 1172641 11728682 BSVBI22_A1192 Brucella suis VBI22 RNA methyltransferase YP_005154873.1 1171811 R 1112912 CDS YP_005154874.1 376280868 11728683 1172821..1173405 1 NC_016797.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382; ThiJ/PfpI family protein 1173405 11728683 BSVBI22_A1193 Brucella suis VBI22 ThiJ/PfpI family protein YP_005154874.1 1172821 D 1112912 CDS YP_005154875.1 376280869 11728684 1173494..1173904 1 NC_016797.1 identified by similarity to OMNI:NTL03PA04336; hypothetical protein 1173904 11728684 BSVBI22_A1194 Brucella suis VBI22 hypothetical protein YP_005154875.1 1173494 D 1112912 CDS YP_005154876.1 376280870 11728685 1174032..1175246 1 NC_016797.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1175246 11728685 BSVBI22_A1195 Brucella suis VBI22 isocitrate dehydrogenase YP_005154876.1 1174032 D 1112912 CDS YP_005154877.1 376280871 11728686 1175468..1176913 1 NC_016797.1 identified by similarity to SP:P00634; match to protein family HMM PF00245; alkaline phosphatase 1176913 phoA 11728686 phoA Brucella suis VBI22 alkaline phosphatase YP_005154877.1 1175468 D 1112912 CDS YP_005154878.1 376280872 11728687 complement(1177065..1179722) 1 NC_016797.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1179722 alaS 11728687 alaS Brucella suis VBI22 alanyl-tRNA synthetase YP_005154878.1 1177065 R 1112912 CDS YP_005154879.1 376280873 11728688 complement(1180115..1181200) 1 NC_016797.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1181200 recA 11728688 recA Brucella suis VBI22 recombinase A YP_005154879.1 1180115 R 1112912 CDS YP_005154880.1 376280874 11728689 complement(1181370..1181495) 1 NC_016797.1 hypothetical protein 1181495 11728689 BSVBI22_A1199 Brucella suis VBI22 hypothetical protein YP_005154880.1 1181370 R 1112912 CDS YP_005154881.1 376280875 11728690 complement(1181531..1182193) 1 NC_016797.1 identified by match to protein family HMM PF00691; OmpA family protein 1182193 11728690 BSVBI22_A1200 Brucella suis VBI22 OmpA family protein YP_005154881.1 1181531 R 1112912 CDS YP_005154882.1 376280876 11728691 complement(1182280..1182864) 1 NC_016797.1 identified by similarity to GP:15075335; putative lipoprotein 1182864 11728691 BSVBI22_A1201 Brucella suis VBI22 putative lipoprotein YP_005154882.1 1182280 R 1112912 CDS YP_005154883.1 376280877 11728692 complement(1182988..1184301) 1 NC_016797.1 identified by match to protein family HMM PF00004; recombination factor protein RarA 1184301 11728692 BSVBI22_A1202 Brucella suis VBI22 recombination factor protein RarA YP_005154883.1 1182988 R 1112912 CDS YP_005154884.1 376280878 11728693 complement(1184448..1185872) 1 NC_016797.1 identified by similarity to EGAD:18959; match to protein family HMM PF00089; match to protein family HMM PF00595; serine protease 1185872 11728693 BSVBI22_A1203 Brucella suis VBI22 serine protease YP_005154884.1 1184448 R 1112912 CDS YP_005154885.1 376280879 11728694 complement(1186152..1186580) 1 NC_016797.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1186580 rplQ 11728694 rplQ Brucella suis VBI22 50S ribosomal protein L17 YP_005154885.1 1186152 R 1112912 CDS YP_005154886.1 376280880 11728695 complement(1186742..1187755) 1 NC_016797.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1187755 rpoA 11728695 rpoA Brucella suis VBI22 DNA-directed RNA polymerase subunit alpha YP_005154886.1 1186742 R 1112912 CDS YP_005154887.1 376280881 11728696 complement(1187871..1188260) 1 NC_016797.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1188260 rpsK 11728696 rpsK Brucella suis VBI22 30S ribosomal protein S11 YP_005154887.1 1187871 R 1112912 CDS YP_005154888.1 376280882 11728697 complement(1188388..1188756) 1 NC_016797.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1188756 rpsM 11728697 rpsM Brucella suis VBI22 30S ribosomal protein S13 YP_005154888.1 1188388 R 1112912 CDS YP_005154889.1 376280883 11728698 complement(1189066..1189650) 1 NC_016797.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1189650 adk 11728698 adk Brucella suis VBI22 adenylate kinase YP_005154889.1 1189066 R 1112912 CDS YP_005154890.1 376280884 11728699 complement(1189647..1190987) 1 NC_016797.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1190987 secY 11728699 secY Brucella suis VBI22 preprotein translocase subunit SecY YP_005154890.1 1189647 R 1112912 CDS YP_005154891.1 376280885 11728700 complement(1191148..1191618) 1 NC_016797.1 late assembly protein; 50S ribosomal protein L15 1191618 rplO 11728700 rplO Brucella suis VBI22 50S ribosomal protein L15 YP_005154891.1 1191148 R 1112912 CDS YP_005154892.1 376280886 11728701 complement(1191639..1191836) 1 NC_016797.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 1191836 rpmD 11728701 rpmD Brucella suis VBI22 50S ribosomal protein L30 YP_005154892.1 1191639 R 1112912 CDS YP_005154893.1 376280887 11728702 complement(1191954..1192514) 1 NC_016797.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1192514 rpsE 11728702 rpsE Brucella suis VBI22 30S ribosomal protein S5 YP_005154893.1 1191954 R 1112912 CDS YP_005154894.1 376280888 11728703 complement(1192556..1192918) 1 NC_016797.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1192918 rplR 11728703 rplR Brucella suis VBI22 50S ribosomal protein L18 YP_005154894.1 1192556 R 1112912 CDS YP_005154895.1 376280889 11728704 complement(1192931..1193464) 1 NC_016797.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1193464 rplF 11728704 rplF Brucella suis VBI22 50S ribosomal protein L6 YP_005154895.1 1192931 R 1112912 CDS YP_005154896.1 376280890 11728705 complement(1193503..1193901) 1 NC_016797.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1193901 rpsH 11728705 rpsH Brucella suis VBI22 30S ribosomal protein S8 YP_005154896.1 1193503 R 1112912 CDS YP_005154897.1 376280891 11728706 complement(1193912..1194217) 1 NC_016797.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1194217 rpsN 11728706 rpsN Brucella suis VBI22 30S ribosomal protein S14 YP_005154897.1 1193912 R 1112912 CDS YP_005154898.1 376280892 11728707 complement(1194245..1194802) 1 NC_016797.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1194802 rplE 11728707 rplE Brucella suis VBI22 50S ribosomal protein L5 YP_005154898.1 1194245 R 1112912 CDS YP_005154899.1 376280893 11728708 complement(1194795..1195106) 1 NC_016797.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1195106 rplX 11728708 rplX Brucella suis VBI22 50S ribosomal protein L24 YP_005154899.1 1194795 R 1112912 CDS YP_005154900.1 376280894 11728709 complement(1195119..1195487) 1 NC_016797.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1195487 rplN 11728709 rplN Brucella suis VBI22 50S ribosomal protein L14 YP_005154900.1 1195119 R 1112912 CDS YP_005154901.1 376280895 11728710 complement(1195556..1195798) 1 NC_016797.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1195798 rpsQ 11728710 rpsQ Brucella suis VBI22 30S ribosomal protein S17 YP_005154901.1 1195556 R 1112912 CDS YP_005154902.1 376280896 11728711 complement(1195811..1196011) 1 NC_016797.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1196011 rpmC 11728711 rpmC Brucella suis VBI22 50S ribosomal protein L29 YP_005154902.1 1195811 R 1112912 CDS YP_005154903.1 376280897 11728712 complement(1196024..1196437) 1 NC_016797.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1196437 rplP 11728712 rplP Brucella suis VBI22 50S ribosomal protein L16 YP_005154903.1 1196024 R 1112912 CDS YP_005154904.1 376280898 11728713 complement(1196476..1197186) 1 NC_016797.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1197186 rpsC 11728713 rpsC Brucella suis VBI22 30S ribosomal protein S3 YP_005154904.1 1196476 R 1112912 CDS YP_005154905.1 376280899 11728714 complement(1197186..1197575) 1 NC_016797.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1197575 rplV 11728714 rplV Brucella suis VBI22 50S ribosomal protein L22 YP_005154905.1 1197186 R 1112912 CDS YP_005154906.1 376280900 11728715 complement(1197578..1197856) 1 NC_016797.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1197856 rpsS 11728715 rpsS Brucella suis VBI22 30S ribosomal protein S19 YP_005154906.1 1197578 R 1112912 CDS YP_005154907.1 376280901 11728716 complement(1197872..1198705) 1 NC_016797.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1198705 rplB 11728716 rplB Brucella suis VBI22 50S ribosomal protein L2 YP_005154907.1 1197872 R 1112912 CDS YP_005154908.1 376280902 11728717 complement(1198727..1199020) 1 NC_016797.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1199020 rplW 11728717 rplW Brucella suis VBI22 50S ribosomal protein L23 YP_005154908.1 1198727 R 1112912 CDS YP_005154909.1 376280903 11728718 complement(1199017..1199637) 1 NC_016797.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1199637 rplD 11728718 rplD Brucella suis VBI22 50S ribosomal protein L4 YP_005154909.1 1199017 R 1112912 CDS YP_005154910.1 376280904 11728719 complement(1199637..1200350) 1 NC_016797.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1200350 rplC 11728719 rplC Brucella suis VBI22 50S ribosomal protein L3 YP_005154910.1 1199637 R 1112912 CDS YP_005154911.1 376280905 11728720 complement(1200380..1200688) 1 NC_016797.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1200688 rpsJ 11728720 rpsJ Brucella suis VBI22 30S ribosomal protein S10 YP_005154911.1 1200380 R 1112912 CDS YP_005154912.1 376280906 11728721 complement(1200749..1201924) 1 NC_016797.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1201924 tuf 11728721 tuf Brucella suis VBI22 elongation factor Tu YP_005154912.1 1200749 R 1112912 CDS YP_005154913.1 376280907 11728722 complement(1201988..1204072) 1 NC_016797.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1204072 fusA 11728722 fusA Brucella suis VBI22 elongation factor G YP_005154913.1 1201988 R 1112912 CDS YP_005154914.1 376280908 11728723 complement(1204103..1204573) 1 NC_016797.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1204573 rpsG 11728723 rpsG Brucella suis VBI22 30S ribosomal protein S7 YP_005154914.1 1204103 R 1112912 CDS YP_005154915.1 376280909 11728724 complement(1204640..1205011) 1 NC_016797.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1205011 rpsL 11728724 rpsL Brucella suis VBI22 30S ribosomal protein S12 YP_005154915.1 1204640 R 1112912 CDS YP_005154916.1 376280910 11728725 complement(1205101..1205235) 1 NC_016797.1 hypothetical protein 1205235 11728725 BSVBI22_A1235 Brucella suis VBI22 hypothetical protein YP_005154916.1 1205101 R 1112912 CDS YP_005154917.1 376280911 11728726 complement(1205242..1205346) 1 NC_016797.1 hypothetical protein 1205346 11728726 BSVBI22_A1236 Brucella suis VBI22 hypothetical protein YP_005154917.1 1205242 R 1112912 CDS YP_005154918.1 376280912 11728727 1205443..1205814 1 NC_016797.1 identified by similarity to GP:15074283; hypothetical protein 1205814 11728727 BSVBI22_A1237 Brucella suis VBI22 hypothetical protein YP_005154918.1 1205443 D 1112912 CDS YP_005154919.1 376280913 11728728 complement(1205921..1210123) 1 NC_016797.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1210123 rpoC 11728728 rpoC Brucella suis VBI22 DNA-directed RNA polymerase subunit beta' YP_005154919.1 1205921 R 1112912 CDS YP_005154920.1 376280914 11728729 complement(1210272..1214405) 1 NC_016797.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1214405 rpoB 11728729 rpoB Brucella suis VBI22 DNA-directed RNA polymerase subunit beta YP_005154920.1 1210272 R 1112912 CDS YP_005154921.1 376280915 11728730 1214391..1214495 1 NC_016797.1 hypothetical protein 1214495 11728730 BSVBI22_A1240 Brucella suis VBI22 hypothetical protein YP_005154921.1 1214391 D 1112912 CDS YP_005154922.1 376280916 11728731 complement(1214613..1214987) 1 NC_016797.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1214987 rplL 11728731 rplL Brucella suis VBI22 50S ribosomal protein L7/L12 YP_005154922.1 1214613 R 1112912 CDS YP_005154923.1 376280917 11728732 complement(1215039..1215557) 1 NC_016797.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1215557 rplJ 11728732 rplJ Brucella suis VBI22 50S ribosomal protein L10 YP_005154923.1 1215039 R 1112912 CDS YP_005154924.1 376280918 11728733 complement(1215948..1216649) 1 NC_016797.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1216649 rplA 11728733 rplA Brucella suis VBI22 50S ribosomal protein L1 YP_005154924.1 1215948 R 1112912 CDS YP_005154925.1 376280919 11728734 complement(1216654..1217082) 1 NC_016797.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1217082 rplK 11728734 rplK Brucella suis VBI22 50S ribosomal protein L11 YP_005154925.1 1216654 R 1112912 CDS YP_005154926.1 376280920 11728735 complement(1217285..1217812) 1 NC_016797.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1217812 nusG 11728735 nusG Brucella suis VBI22 transcription antitermination protein NusG YP_005154926.1 1217285 R 1112912 CDS YP_005154927.1 376280921 11728736 complement(1217836..1218075) 1 NC_016797.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1218075 secE 11728736 secE Brucella suis VBI22 preprotein translocase subunit SecE YP_005154927.1 1217836 R 1112912 CDS YP_005154928.1 376280922 11728738 complement(1218709..1219884) 1 NC_016797.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1219884 tuf 11728738 tuf Brucella suis VBI22 elongation factor Tu YP_005154928.1 1218709 R 1112912 CDS YP_005154929.1 376280923 11728739 1219835..1220035 1 NC_016797.1 hypothetical protein 1220035 11728739 BSVBI22_A1248 Brucella suis VBI22 hypothetical protein YP_005154929.1 1219835 D 1112912 CDS YP_005154930.1 376280924 11728742 complement(1220267..1220383) 1 NC_016797.1 hypothetical protein 1220383 11728742 BSVBI22_A1249 Brucella suis VBI22 hypothetical protein YP_005154930.1 1220267 R 1112912 CDS YP_005154931.1 376280925 11728743 1220515..1221375 1 NC_016797.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00186; RNA methyltransferase 1221375 11728743 BSVBI22_A1250 Brucella suis VBI22 RNA methyltransferase YP_005154931.1 1220515 D 1112912 CDS YP_005154932.1 376280926 11728745 complement(1222037..1222798) 1 NC_016797.1 identified by match to protein family HMM PF01694; rhomboid family protein 1222798 11728745 BSVBI22_A1252 Brucella suis VBI22 rhomboid family protein YP_005154932.1 1222037 R 1112912 CDS YP_005154933.1 376280927 11728746 1222859..1222954 1 NC_016797.1 hypothetical protein 1222954 11728746 BSVBI22_A1253 Brucella suis VBI22 hypothetical protein YP_005154933.1 1222859 D 1112912 CDS YP_005154934.1 376280928 11728747 1223136..1223798 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0144; hypothetical protein 1223798 11728747 BSVBI22_A1254 Brucella suis VBI22 hypothetical protein YP_005154934.1 1223136 D 1112912 CDS YP_005154935.1 376280929 11728748 1224042..1224647 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0142; hypothetical protein 1224647 11728748 BSVBI22_A1255 Brucella suis VBI22 hypothetical protein YP_005154935.1 1224042 D 1112912 CDS YP_005154936.1 376280930 11728749 complement(1224726..1225253) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0140; match to protein family HMM PF00132; ferripyochelin-binding protein 1225253 11728749 BSVBI22_A1256 Brucella suis VBI22 ferripyochelin-binding protein YP_005154936.1 1224726 R 1112912 CDS YP_005154937.1 376280931 11728750 complement(1225524..1225778) 1 NC_016797.1 identified by similarity to GP:15074417; hypothetical protein 1225778 11728750 BSVBI22_A1257 Brucella suis VBI22 hypothetical protein YP_005154937.1 1225524 R 1112912 CDS YP_005154938.1 376280932 11728751 complement(1226026..1226826) 1 NC_016797.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172; serine acetyltransferase 1226826 cysE 11728751 cysE Brucella suis VBI22 serine acetyltransferase YP_005154938.1 1226026 R 1112912 CDS YP_005154939.1 376280933 11728752 1226866..1226988 1 NC_016797.1 hypothetical protein 1226988 11728752 BSVBI22_A1259 Brucella suis VBI22 hypothetical protein YP_005154939.1 1226866 D 1112912 CDS YP_005154940.1 376280934 11728753 complement(1227025..1227795) 1 NC_016797.1 identified by match to protein family HMM PF00561; alpha/beta fold family hydrolase 1227795 11728753 BSVBI22_A1260 Brucella suis VBI22 alpha/beta fold family hydrolase YP_005154940.1 1227025 R 1112912 CDS YP_005154941.1 376280935 11728754 complement(1227829..1228308) 1 NC_016797.1 identified by similarity to GP:14021198; match to protein family HMM PF02643; hypothetical protein 1228308 11728754 BSVBI22_A1261 Brucella suis VBI22 hypothetical protein YP_005154941.1 1227829 R 1112912 CDS YP_005154942.1 376280936 11728755 complement(1228682..1229263) 1 NC_016797.1 identified by match to protein family HMM PF00313; cold-shock family protein 1229263 11728755 BSVBI22_A1262 Brucella suis VBI22 cold-shock family protein YP_005154942.1 1228682 R 1112912 CDS YP_005154943.1 376280937 11728756 complement(1229387..1229557) 1 NC_016797.1 hypothetical protein 1229557 11728756 BSVBI22_A1263 Brucella suis VBI22 hypothetical protein YP_005154943.1 1229387 R 1112912 CDS YP_005154944.1 376280938 11728757 1229626..1230066 1 NC_016797.1 identified by match to protein family HMM PF00903; lactoylglutathione lyase 1230066 gloA 11728757 gloA Brucella suis VBI22 lactoylglutathione lyase YP_005154944.1 1229626 D 1112912 CDS YP_005154945.1 376280939 11728758 complement(1230118..1231146) 1 NC_016797.1 identified by similarity to OMNI:NT01MC4682; hypothetical protein 1231146 11728758 BSVBI22_A1265 Brucella suis VBI22 hypothetical protein YP_005154945.1 1230118 R 1112912 CDS YP_005154946.1 376280940 11728759 complement(1231308..1233092) 1 NC_016797.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644; single-stranded-DNA-specific exonuclease RecJ 1233092 recJ 11728759 recJ Brucella suis VBI22 single-stranded-DNA-specific exonuclease RecJ YP_005154946.1 1231308 R 1112912 CDS YP_005154947.1 376280941 11728760 complement(1233142..1234203) 1 NC_016797.1 identified by similarity to EGAD:14437; match to protein family HMM PF01820; match to protein family HMM TIGR01205; D-alanine--D-alanine ligase 1234203 ddlA 11728760 ddlA Brucella suis VBI22 D-alanine--D-alanine ligase YP_005154947.1 1233142 R 1112912 CDS YP_005154948.1 376280942 11728761 1234232..1234372 1 NC_016797.1 hypothetical protein 1234372 11728761 BSVBI22_A1268 Brucella suis VBI22 hypothetical protein YP_005154948.1 1234232 D 1112912 CDS YP_005154949.1 376280943 11728762 complement(1234551..1235537) 1 NC_016797.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 1235537 glpX 11728762 glpX Brucella suis VBI22 fructose 1,6-bisphosphatase II YP_005154949.1 1234551 R 1112912 CDS YP_005154950.1 376280944 11728763 complement(1235930..1237249) 1 NC_016797.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1237249 hom 11728763 hom Brucella suis VBI22 homoserine dehydrogenase YP_005154950.1 1235930 R 1112912 CDS YP_005154951.1 376280945 11728764 complement(1237385..1238605) 1 NC_016797.1 identified by match to protein family HMM PF00155; aminotransferase 1238605 11728764 BSVBI22_A1271 Brucella suis VBI22 aminotransferase YP_005154951.1 1237385 R 1112912 CDS YP_005154952.1 376280946 11728765 complement(1238736..1239167) 1 NC_016797.1 hypothetical protein 1239167 11728765 BSVBI22_A1272 Brucella suis VBI22 hypothetical protein YP_005154952.1 1238736 R 1112912 CDS YP_005154953.1 376280947 11728766 1239572..1240852 1 NC_016797.1 identified by similarity to GP:14021808; hypothetical protein 1240852 11728766 BSVBI22_A1273 Brucella suis VBI22 hypothetical protein YP_005154953.1 1239572 D 1112912 CDS YP_005154954.1 376280948 11728769 1241463..1241747 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0128; hypothetical protein 1241747 11728769 BSVBI22_A1274 Brucella suis VBI22 hypothetical protein YP_005154954.1 1241463 D 1112912 CDS YP_005154955.1 376280949 11728770 1241881..1241973 1 NC_016797.1 hypothetical protein 1241973 11728770 BSVBI22_A1275 Brucella suis VBI22 hypothetical protein YP_005154955.1 1241881 D 1112912 CDS YP_005154956.1 376280950 11728771 1241970..1242062 1 NC_016797.1 hypothetical protein 1242062 11728771 BSVBI22_A1276 Brucella suis VBI22 hypothetical protein YP_005154956.1 1241970 D 1112912 CDS YP_005154957.1 376280951 11728772 1242071..1242787 1 NC_016797.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 1242787 sfsA 11728772 sfsA Brucella suis VBI22 sugar fermentation stimulation protein A YP_005154957.1 1242071 D 1112912 CDS YP_005154958.1 376280952 11728773 1242787..1243614 1 NC_016797.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1243614 map 11728773 map Brucella suis VBI22 methionine aminopeptidase YP_005154958.1 1242787 D 1112912 CDS YP_005154959.1 376280953 11728774 1243670..1244419 1 NC_016797.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1244419 radC 11728774 radC Brucella suis VBI22 DNA repair protein RadC YP_005154959.1 1243670 D 1112912 CDS YP_005154960.1 376280954 11728775 1244621..1245259 1 NC_016797.1 identified by similarity to GP:14018349; hypothetical protein 1245259 11728775 BSVBI22_A1280 Brucella suis VBI22 hypothetical protein YP_005154960.1 1244621 D 1112912 CDS YP_005154961.1 376280955 11728776 complement(1245548..1246753) 1 NC_016797.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01468; precorrin-6Y C5,15-methyltransferase 1246753 cobL 11728776 cobL Brucella suis VBI22 precorrin-6Y C5,15-methyltransferase YP_005154961.1 1245548 R 1112912 CDS YP_005154962.1 376280956 11728777 1246827..1248122 1 NC_016797.1 identified by match to protein family HMM PF01077; match to protein family HMM PF03460; nitrite reductase family protein 1248122 11728777 BSVBI22_A1282 Brucella suis VBI22 nitrite reductase family protein YP_005154962.1 1246827 D 1112912 CDS YP_005154963.1 376280957 11728778 1248132..1248758 1 NC_016797.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; precorrin-8X methylmutase 1248758 cobH 11728778 cobH Brucella suis VBI22 precorrin-8X methylmutase YP_005154963.1 1248132 D 1112912 CDS YP_005154964.1 376280958 11728779 1248758..1249492 1 NC_016797.1 catalyzes the formation of precorrin-3 from precorrin-2; precorrin-2 C(20)-methyltransferase 1249492 cobI 11728779 cobI Brucella suis VBI22 precorrin-2 C(20)-methyltransferase YP_005154964.1 1248758 D 1112912 CDS YP_005154965.1 376280959 11728780 1249438..1251183 1 NC_016797.1 identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466; cbiG protein/precorrin-3B C17-methyltransferase 1251183 11728780 BSVBI22_A1285 Brucella suis VBI22 cbiG protein/precorrin-3B C17-methyltransferase YP_005154965.1 1249438 D 1112912 CDS YP_005154966.1 376280960 11728781 complement(1251239..1251706) 1 NC_016797.1 hypothetical protein 1251706 11728781 BSVBI22_A1286 Brucella suis VBI22 hypothetical protein YP_005154966.1 1251239 R 1112912 CDS YP_005154967.1 376280961 11728782 complement(1251831..1252727) 1 NC_016797.1 phospholipase/carboxylesterase family protein 1252727 11728782 BSVBI22_A1287 Brucella suis VBI22 phospholipase/carboxylesterase family protein YP_005154967.1 1251831 R 1112912 CDS YP_005154968.1 376280962 11728783 complement(1252731..1253252) 1 NC_016797.1 identified by match to protein family HMM PF01613; monooxygenase 1253252 11728783 BSVBI22_A1288 Brucella suis VBI22 monooxygenase YP_005154968.1 1252731 R 1112912 CDS YP_005154969.1 376280963 11728784 1253397..1254488 1 NC_016797.1 identified by similarity to SP:P02917; match to protein family HMM PF01094; branched-chain amino acid ABC transporter substrate-binding protein 1254488 11728784 BSVBI22_A1289 Brucella suis VBI22 branched-chain amino acid ABC transporter substrate-binding protein YP_005154969.1 1253397 D 1112912 CDS YP_005154970.1 376280964 11728785 complement(1254474..1255469) 1 NC_016797.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein 1255469 cobD 11728785 cobD Brucella suis VBI22 cobalamin biosynthesis protein YP_005154970.1 1254474 R 1112912 CDS YP_005154971.1 376280965 11728786 complement(1255494..1256492) 1 NC_016797.1 identified by similarity to SP:P21633; match to protein family HMM PF00155; cobC protein 1256492 cobC 11728786 cobC Brucella suis VBI22 cobC protein YP_005154971.1 1255494 R 1112912 CDS YP_005154972.1 376280966 11728787 complement(1256489..1257799) 1 NC_016797.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 1257799 cobB 11728787 cobB Brucella suis VBI22 cobyrinic acid a,c-diamide synthase YP_005154972.1 1256489 R 1112912 CDS YP_005154973.1 376280967 11728788 complement(1257796..1258644) 1 NC_016797.1 identified by similarity to SP:P21631; match to protein family HMM PF00590; match to protein family HMM TIGR01469; uroporphyrin-III C-methyltransferase 1258644 cobA 11728788 cobA Brucella suis VBI22 uroporphyrin-III C-methyltransferase YP_005154973.1 1257796 R 1112912 CDS YP_005154974.1 376280968 11728789 1258735..1259841 1 NC_016797.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase 1259841 cbiD 11728789 cbiD Brucella suis VBI22 cobalt-precorrin-6A synthase YP_005154974.1 1258735 D 1112912 CDS YP_005154975.1 376280969 11728790 1259828..1260574 1 NC_016797.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase 1260574 cobK 11728790 cobK Brucella suis VBI22 cobalt-precorrin-6x reductase YP_005154975.1 1259828 D 1112912 CDS YP_005154976.1 376280970 11728791 complement(1260563..1261321) 1 NC_016797.1 identified by similarity to SP:P21922; match to protein family HMM PF00590; match to protein family HMM TIGR01465; precorrin-4 C(11)-methyltransferase 1261321 cobM 11728791 cobM Brucella suis VBI22 precorrin-4 C(11)-methyltransferase YP_005154976.1 1260563 R 1112912 CDS YP_005154977.1 376280971 11728792 complement(1261381..1261776) 1 NC_016797.1 precorrin-3B C17-methyltransferase 1261776 11728792 BSVBI22_A1297 Brucella suis VBI22 precorrin-3B C17-methyltransferase YP_005154977.1 1261381 R 1112912 CDS YP_005154978.1 376280972 11728793 complement(1261769..1262215) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0945; hypothetical protein 1262215 11728793 BSVBI22_A1298 Brucella suis VBI22 hypothetical protein YP_005154978.1 1261769 R 1112912 CDS YP_005154979.1 376280973 11728794 1262375..1263160 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0946; match to protein family HMM PF01925; hypothetical protein 1263160 11728794 BSVBI22_A1299 Brucella suis VBI22 hypothetical protein YP_005154979.1 1262375 D 1112912 CDS YP_005154980.1 376280974 11728795 complement(1263157..1263585) 1 NC_016797.1 identified by match to protein family HMM PF00892; hypothetical protein 1263585 11728795 BSVBI22_A1300 Brucella suis VBI22 hypothetical protein YP_005154980.1 1263157 R 1112912 CDS YP_005154981.1 376280975 11728796 complement(1263585..1264193) 1 NC_016797.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1264193 cobO 11728796 cobO Brucella suis VBI22 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_005154981.1 1263585 R 1112912 CDS YP_005154982.1 376280976 11728797 complement(1264216..1268007) 1 NC_016797.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN 1268007 cobN 11728797 cobN Brucella suis VBI22 cobaltochelatase subunit CobN YP_005154982.1 1264216 R 1112912 CDS YP_005154983.1 376280977 11728798 complement(1268007..1269056) 1 NC_016797.1 identified by match to protein family HMM PF02492; cobW protein 1269056 11728798 BSVBI22_A1303 Brucella suis VBI22 cobW protein YP_005154983.1 1268007 R 1112912 CDS YP_005154984.1 376280978 11728799 complement(1269060..1269581) 1 NC_016797.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 1269581 cobU 11728799 cobU Brucella suis VBI22 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase YP_005154984.1 1269060 R 1112912 CDS YP_005154985.1 376280979 11728800 complement(1269587..1270303) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1033; hypothetical protein 1270303 11728800 BSVBI22_A1305 Brucella suis VBI22 hypothetical protein YP_005154985.1 1269587 R 1112912 CDS YP_005154986.1 376280980 11728801 complement(1270392..1270580) 1 NC_016797.1 identified by similarity to GP:14022104; hypothetical protein 1270580 11728801 BSVBI22_A1306 Brucella suis VBI22 hypothetical protein YP_005154986.1 1270392 R 1112912 CDS YP_005154987.1 376280981 11728802 complement(1270894..1272345) 1 NC_016797.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase 1272345 cobQ 11728802 cobQ Brucella suis VBI22 cobyric acid synthase YP_005154987.1 1270894 R 1112912 CDS YP_005154988.1 376280982 11728803 complement(1272356..1272505) 1 NC_016797.1 hypothetical protein 1272505 11728803 BSVBI22_A1308 Brucella suis VBI22 hypothetical protein YP_005154988.1 1272356 R 1112912 CDS YP_005154989.1 376280983 11728805 1273810..1274700 1 NC_016797.1 identified by match to protein family HMM PF03446; match to protein family HMM TIGR01692; 3-hydroxyisobutyrate dehydrogenase 1274700 mmsB 11728805 mmsB Brucella suis VBI22 3-hydroxyisobutyrate dehydrogenase YP_005154989.1 1273810 D 1112912 CDS YP_005154990.1 376280984 11728806 complement(1274936..1275103) 1 NC_016797.1 hypothetical protein 1275103 11728806 BSVBI22_A1311 Brucella suis VBI22 hypothetical protein YP_005154990.1 1274936 R 1112912 CDS YP_005154991.1 376280985 11728807 complement(1275096..1275230) 1 NC_016797.1 identified by similarity to OMNI:CC3473; hypothetical protein 1275230 11728807 BSVBI22_A1312 Brucella suis VBI22 hypothetical protein YP_005154991.1 1275096 R 1112912 CDS YP_005154992.1 376280986 11728808 complement(1275298..1275399) 1 NC_016797.1 hypothetical protein 1275399 11728808 BSVBI22_A1313 Brucella suis VBI22 hypothetical protein YP_005154992.1 1275298 R 1112912 CDS YP_005154993.1 376280987 11728810 1276777..1277775 1 NC_016797.1 identified by match to protein family HMM PF00165; match to protein family HMM PF01965; AraC family transcriptional regulator 1277775 11728810 BSVBI22_A1315 Brucella suis VBI22 AraC family transcriptional regulator YP_005154993.1 1276777 D 1112912 CDS YP_005154994.1 376280988 11728812 complement(1280688..1280978) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1001; hypothetical protein 1280978 11728812 BSVBI22_A1317 Brucella suis VBI22 hypothetical protein YP_005154994.1 1280688 R 1112912 CDS YP_005154995.1 376280989 11728814 complement(1283790..1284374) 1 NC_016797.1 hypothetical protein 1284374 11728814 BSVBI22_A1319 Brucella suis VBI22 hypothetical protein YP_005154995.1 1283790 R 1112912 CDS YP_005154996.1 376280990 11728815 1284426..1286963 1 NC_016797.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 1286963 11728815 BSVBI22_A1320 Brucella suis VBI22 bifunctional preprotein translocase subunit SecD/SecF YP_005154996.1 1284426 D 1112912 CDS YP_005154997.1 376280991 11728816 1287041..1288900 1 NC_016797.1 identified by match to protein family HMM PF00999; match to protein family HMM PF02254; match to protein family HMM TIGR00932; potassium efflux system family protein 1288900 11728816 BSVBI22_A1321 Brucella suis VBI22 potassium efflux system family protein YP_005154997.1 1287041 D 1112912 CDS YP_005154998.1 376280992 11728817 1288900..1289871 1 NC_016797.1 hypothetical protein 1289871 11728817 BSVBI22_A1322 Brucella suis VBI22 hypothetical protein YP_005154998.1 1288900 D 1112912 CDS YP_005154999.1 376280993 11728818 1290098..1290703 1 NC_016797.1 identified by similarity to GP:15074696; hypothetical protein 1290703 11728818 BSVBI22_A1323 Brucella suis VBI22 hypothetical protein YP_005154999.1 1290098 D 1112912 CDS YP_005155000.1 376280994 11728819 complement(1290749..1291579) 1 NC_016797.1 identified by similarity to SP:P16702; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02140; sulfate ABC transporter, permease protein 1291579 cysW-2 11728819 cysW-2 Brucella suis VBI22 sulfate ABC transporter, permease protein YP_005155000.1 1290749 R 1112912 CDS YP_005155001.1 376280995 11728820 complement(1291566..1292432) 1 NC_016797.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate ABC transporter permease 1292432 11728820 BSVBI22_A1325 Brucella suis VBI22 sulfate ABC transporter permease YP_005155001.1 1291566 R 1112912 CDS YP_005155002.1 376280996 11728821 complement(1292559..1293563) 1 NC_016797.1 identified by similarity to SP:P06997; match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate ABC transporter, sulfate-binding protein, putative 1293563 11728821 BSVBI22_A1326 Brucella suis VBI22 sulfate ABC transporter, sulfate-binding protein, putative YP_005155002.1 1292559 R 1112912 CDS YP_005155003.1 376280997 11728822 complement(1293829..1294014) 1 NC_016797.1 hypothetical protein 1294014 11728822 BSVBI22_A1327 Brucella suis VBI22 hypothetical protein YP_005155003.1 1293829 R 1112912 CDS YP_005155004.1 376280998 11728823 complement(1294194..1295750) 1 NC_016797.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; hypothetical protein 1295750 11728823 BSVBI22_A1328 Brucella suis VBI22 hypothetical protein YP_005155004.1 1294194 R 1112912 CDS YP_005155005.1 376280999 11728824 complement(1296180..1296842) 1 NC_016797.1 identified by match to protein family HMM PF00597; dedA family protein 1296842 11728824 BSVBI22_A1329 Brucella suis VBI22 dedA family protein YP_005155005.1 1296180 R 1112912 CDS YP_005155006.1 376281000 11728825 complement(1297145..1297312) 1 NC_016797.1 hypothetical protein 1297312 11728825 BSVBI22_A1330 Brucella suis VBI22 hypothetical protein YP_005155006.1 1297145 R 1112912 CDS YP_005155007.1 376281001 11728827 1297725..1298279 1 NC_016797.1 identified by similarity to EGAD:154080; match to protein family HMM PF00036; acid-shock protein 1298279 11728827 BSVBI22_A1331 Brucella suis VBI22 acid-shock protein YP_005155007.1 1297725 D 1112912 CDS YP_005155008.1 376281002 11728828 complement(1298413..1298835) 1 NC_016797.1 identified by match to protein family HMM PF05025; fucose operon fucU protein 1298835 fucU 11728828 fucU Brucella suis VBI22 fucose operon fucU protein YP_005155008.1 1298413 R 1112912 CDS YP_005155009.1 376281003 11728829 complement(1298929..1299738) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3842; match to protein family HMM PF00106; short chain dehydrogenase 1299738 11728829 BSVBI22_A1333 Brucella suis VBI22 short chain dehydrogenase YP_005155009.1 1298929 R 1112912 CDS YP_005155010.1 376281004 11728932 complement(1299753..1300532) 1 NC_016797.1 identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein 1300532 11728932 BSVBI22_A1334 Brucella suis VBI22 sugar ABC transporter ATP-binding protein YP_005155010.1 1299753 R 1112912 CDS YP_005155011.1 376281005 11728933 complement(1300546..1301673) 1 NC_016797.1 identified by similarity to GP:6273663; match to protein family HMM PF02653; sugar ABC transporter permease 1301673 11728933 BSVBI22_A1335 Brucella suis VBI22 sugar ABC transporter permease YP_005155011.1 1300546 R 1112912 CDS YP_005155012.1 376281006 11728934 complement(1301706..1301798) 1 NC_016797.1 hypothetical protein 1301798 11728934 BSVBI22_A1336 Brucella suis VBI22 hypothetical protein YP_005155012.1 1301706 R 1112912 CDS YP_005155013.1 376281007 11728935 complement(1301960..1302889) 1 NC_016797.1 identified by similarity to GP:6273662; match to protein family HMM PF00532; sugar ABC transporter periplasmic sugar-binding protein 1302889 11728935 BSVBI22_A1337 Brucella suis VBI22 sugar ABC transporter periplasmic sugar-binding protein YP_005155013.1 1301960 R 1112912 CDS YP_005155014.1 376281008 11728936 1303268..1304383 1 NC_016797.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase 1304383 11728936 BSVBI22_A1338 Brucella suis VBI22 oxidoreductase YP_005155014.1 1303268 D 1112912 CDS YP_005155015.1 376281009 11728937 complement(1304380..1305156) 1 NC_016797.1 identified by similarity to SP:P15031; match to protein family HMM PF00005; iron compound ABC transporter ATP-binding protein 1305156 11728937 BSVBI22_A1339 Brucella suis VBI22 iron compound ABC transporter ATP-binding protein YP_005155015.1 1304380 R 1112912 CDS YP_005155016.1 376281010 11728938 complement(1305153..1306154) 1 NC_016797.1 identified by match to protein family HMM PF01032; iron compound ABC transporter permease 1306154 11728938 BSVBI22_A1340 Brucella suis VBI22 iron compound ABC transporter permease YP_005155016.1 1305153 R 1112912 CDS YP_005155017.1 376281011 11728939 complement(1306147..1306986) 1 NC_016797.1 identified by similarity to PIR:S54437; match to protein family HMM PF01497; iron compound ABC transporter periplasmic iron compound-binding protein 1306986 11728939 BSVBI22_A1341 Brucella suis VBI22 iron compound ABC transporter periplasmic iron compound-binding protein YP_005155017.1 1306147 R 1112912 CDS YP_005155018.1 376281012 11728940 complement(1307000..1308862) 1 NC_016797.1 identified by similarity to SP:P06129; match to protein family HMM PF00593; iron compound TonB-dependent receptor 1308862 11728940 BSVBI22_A1342 Brucella suis VBI22 iron compound TonB-dependent receptor YP_005155018.1 1307000 R 1112912 CDS YP_005155019.1 376281013 11728941 complement(1309151..1309306) 1 NC_016797.1 hypothetical protein 1309306 11728941 BSVBI22_A1343 Brucella suis VBI22 hypothetical protein YP_005155019.1 1309151 R 1112912 CDS YP_005155020.1 376281014 11728942 complement(1309356..1310468) 1 NC_016797.1 ABC transporter permease 1310468 11728942 BSVBI22_A1344 Brucella suis VBI22 ABC transporter permease YP_005155020.1 1309356 R 1112912 CDS YP_005155021.1 376281015 11728943 complement(1310470..1313238) 1 NC_016797.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein/permease 1313238 11728943 BSVBI22_A1345 Brucella suis VBI22 ABC transporter ATP-binding protein/permease YP_005155021.1 1310470 R 1112912 CDS YP_005155022.1 376281016 11728944 complement(1313235..1314302) 1 NC_016797.1 identified by match to protein family HMM PF00529; HlyD family secretion protein 1314302 11728944 BSVBI22_A1346 Brucella suis VBI22 HlyD family secretion protein YP_005155022.1 1313235 R 1112912 CDS YP_005155023.1 376281017 11728945 1314282..1314461 1 NC_016797.1 hypothetical protein 1314461 11728945 BSVBI22_A1347 Brucella suis VBI22 hypothetical protein YP_005155023.1 1314282 D 1112912 CDS YP_005155024.1 376281018 11728946 complement(1314539..1314775) 1 NC_016797.1 hypothetical protein 1314775 11728946 BSVBI22_A1348 Brucella suis VBI22 hypothetical protein YP_005155024.1 1314539 R 1112912 CDS YP_005155025.1 376281019 11728947 complement(1314848..1316143) 1 NC_016797.1 identified by similarity to OMNI:NTL02EC1981; match to protein family HMM PF02638; hypothetical protein 1316143 11728947 BSVBI22_A1349 Brucella suis VBI22 hypothetical protein YP_005155025.1 1314848 R 1112912 CDS YP_005155026.1 376281020 11728948 complement(1316722..1316898) 1 NC_016797.1 hypothetical protein 1316898 11728948 BSVBI22_A1350 Brucella suis VBI22 hypothetical protein YP_005155026.1 1316722 R 1112912 CDS YP_005155027.1 376281021 11728949 1316958..1317260 1 NC_016797.1 UreA, with UreB and UreC, catalyzes the hydrolysis of urea to ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 1317260 ureA 11728949 ureA Brucella suis VBI22 urease subunit gamma YP_005155027.1 1316958 D 1112912 CDS YP_005155028.1 376281022 11728950 1317309..1317788 1 NC_016797.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) does not seem to be involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo; urease subunit beta 1317788 ureB 11728950 ureB Brucella suis VBI22 urease subunit beta YP_005155028.1 1317309 D 1112912 CDS YP_005155029.1 376281023 11728951 1317828..1319549 1 NC_016797.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1319549 ureC 11728951 ureC Brucella suis VBI22 urease subunit alpha YP_005155029.1 1317828 D 1112912 CDS YP_005155030.1 376281024 11728952 1319597..1320202 1 NC_016797.1 identified by similarity to SP:Q9ZFR8; match to protein family HMM PF02814; match to protein family HMM PF05194; urease accessory protein UreE 1320202 11728952 BSVBI22_A1354 Brucella suis VBI22 urease accessory protein UreE YP_005155030.1 1319597 D 1112912 CDS YP_005155031.1 376281025 11728953 1320174..1320905 1 NC_016797.1 identified by similarity to EGAD:8726; match to protein family HMM PF01730; urease accessory protein UreF 1320905 11728953 BSVBI22_A1355 Brucella suis VBI22 urease accessory protein UreF YP_005155031.1 1320174 D 1112912 CDS YP_005155032.1 376281026 11728954 1320921..1321559 1 NC_016797.1 identified by similarity to SP:P42871; match to protein family HMM PF01495; match to protein family HMM TIGR00101; urease accessory protein UreG 1321559 ureG-2 11728954 ureG-2 Brucella suis VBI22 urease accessory protein UreG YP_005155032.1 1320921 D 1112912 CDS YP_005155033.1 376281027 11728955 1321559..1322467 1 NC_016797.1 identified by similarity to EGAD:20614; match to protein family HMM PF01774; urease accessory protein UreD 1322467 ureD-2 11728955 ureD-2 Brucella suis VBI22 urease accessory protein UreD YP_005155033.1 1321559 D 1112912 CDS YP_005155034.1 376281028 11728956 1322477..1323529 1 NC_016797.1 identified by similarity to GP:1905970; match to protein family HMM PF03253; urea transporter 1323529 11728956 BSVBI22_A1358 Brucella suis VBI22 urea transporter YP_005155034.1 1322477 D 1112912 CDS YP_005155035.1 376281029 11728957 1323556..1324314 1 NC_016797.1 putative lipoprotein 1324314 11728957 BSVBI22_A1359 Brucella suis VBI22 putative lipoprotein YP_005155035.1 1323556 D 1112912 CDS YP_005155036.1 376281030 11728958 1324334..1324969 1 NC_016797.1 catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 1324969 cbiM 11728958 cbiM Brucella suis VBI22 cobalt transport protein CbiM YP_005155036.1 1324334 D 1112912 CDS YP_005155037.1 376281031 11728959 1324966..1325592 1 NC_016797.1 identified by similarity to EGAD:28613; hypothetical protein 1325592 11728959 BSVBI22_A1361 Brucella suis VBI22 hypothetical protein YP_005155037.1 1324966 D 1112912 CDS YP_005155038.1 376281032 11728960 1325589..1326353 1 NC_016797.1 identified by similarity to GP:6138845; match to protein family HMM PF02361; cobalt ABC transporter permease 1326353 11728960 BSVBI22_A1362 Brucella suis VBI22 cobalt ABC transporter permease YP_005155038.1 1325589 D 1112912 CDS YP_005155039.1 376281033 11728961 1326350..1327069 1 NC_016797.1 identified by match to protein family HMM PF00005; cobalt ABC transporter ATP-binding protein 1327069 11728961 BSVBI22_A1363 Brucella suis VBI22 cobalt ABC transporter ATP-binding protein YP_005155039.1 1326350 D 1112912 CDS YP_005155040.1 376281034 11728962 complement(1327090..1327854) 1 NC_016797.1 identified by match to protein family HMM PF02537; match to protein family HMM PF03625; crcB family protein 1327854 11728962 BSVBI22_A1364 Brucella suis VBI22 crcB family protein YP_005155040.1 1327090 R 1112912 CDS YP_005155041.1 376281035 11728963 complement(1327915..1328304) 1 NC_016797.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1328304 ccrB 11728963 ccrB Brucella suis VBI22 camphor resistance protein CrcB YP_005155041.1 1327915 R 1112912 CDS YP_005155042.1 376281036 11728964 1328573..1329598 1 NC_016797.1 hypothetical protein 1329598 11728964 BSVBI22_A1366 Brucella suis VBI22 hypothetical protein YP_005155042.1 1328573 D 1112912 CDS YP_005155043.1 376281037 11728965 complement(1329731..1330186) 1 NC_016797.1 identified by similarity to EGAD:6639; hypothetical protein 1330186 11728965 BSVBI22_A1367 Brucella suis VBI22 hypothetical protein YP_005155043.1 1329731 R 1112912 CDS YP_005155044.1 376281038 11728966 complement(1330317..1331243) 1 NC_016797.1 identified by similarity to EGAD:38480; match to protein family HMM PF02567; match to protein family HMM TIGR00654; PhzF family phenazine biosynthesis protein 1331243 11728966 BSVBI22_A1368 Brucella suis VBI22 PhzF family phenazine biosynthesis protein YP_005155044.1 1330317 R 1112912 CDS YP_005155045.1 376281039 11728967 complement(1331348..1332079) 1 NC_016797.1 NUDIX hydrolase 1332079 11728967 BSVBI22_A1369 Brucella suis VBI22 NUDIX hydrolase YP_005155045.1 1331348 R 1112912 CDS YP_005155046.1 376281040 11728969 1333280..1333795 1 NC_016797.1 identified by similarity to GP:3236220; hypothetical protein 1333795 11728969 BSVBI22_A1371 Brucella suis VBI22 hypothetical protein YP_005155046.1 1333280 D 1112912 CDS YP_005155047.1 376281041 11728970 complement(1333841..1335073) 1 NC_016797.1 identified by match to protein family HMM PF00155; class I aminotransferase 1335073 11728970 BSVBI22_A1372 Brucella suis VBI22 class I aminotransferase YP_005155047.1 1333841 R 1112912 CDS YP_005155048.1 376281042 11728971 complement(1335155..1335436) 1 NC_016797.1 hypothetical protein 1335436 11728971 BSVBI22_A1373 Brucella suis VBI22 hypothetical protein YP_005155048.1 1335155 R 1112912 CDS YP_005155049.1 376281043 11728972 complement(1335458..1336477) 1 NC_016797.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1336477 ilvC 11728972 ilvC Brucella suis VBI22 ketol-acid reductoisomerase YP_005155049.1 1335458 R 1112912 CDS YP_005155050.1 376281044 11728973 complement(1336533..1337174) 1 NC_016797.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1337174 11728973 BSVBI22_A1375 Brucella suis VBI22 TetR family transcriptional regulator YP_005155050.1 1336533 R 1112912 CDS YP_005155051.1 376281045 11728974 1337232..1337387 1 NC_016797.1 hypothetical protein 1337387 11728974 BSVBI22_A1376 Brucella suis VBI22 hypothetical protein YP_005155051.1 1337232 D 1112912 CDS YP_005155052.1 376281046 11728975 complement(1337384..1339339) 1 NC_016797.1 identified by similarity to SP:P30016; match to protein family HMM PF02705; potassium uptake protein 1339339 11728975 BSVBI22_A1377 Brucella suis VBI22 potassium uptake protein YP_005155052.1 1337384 R 1112912 CDS YP_005155053.1 376281047 11728976 complement(1339482..1339640) 1 NC_016797.1 hypothetical protein 1339640 11728976 BSVBI22_A1378 Brucella suis VBI22 hypothetical protein YP_005155053.1 1339482 R 1112912 CDS YP_005155054.1 376281048 11728977 complement(1339709..1340449) 1 NC_016797.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1340449 11728977 BSVBI22_A1379 Brucella suis VBI22 pyridoxine 5'-phosphate synthase YP_005155054.1 1339709 R 1112912 CDS YP_005155055.1 376281049 11728978 1340746..1341147 1 NC_016797.1 hypothetical protein 1341147 11728978 BSVBI22_A1380 Brucella suis VBI22 hypothetical protein YP_005155055.1 1340746 D 1112912 CDS YP_005155056.1 376281050 11728979 complement(1341148..1342269) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1120; hypothetical protein 1342269 11728979 BSVBI22_A1381 Brucella suis VBI22 hypothetical protein YP_005155056.1 1341148 R 1112912 CDS YP_005155057.1 376281051 11728980 complement(1342453..1343025) 1 NC_016797.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1343025 ilvH 11728980 ilvH Brucella suis VBI22 acetolactate synthase 3 regulatory subunit YP_005155057.1 1342453 R 1112912 CDS YP_005155058.1 376281052 11728981 complement(1343044..1344798) 1 NC_016797.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 1344798 ilvB 11728981 ilvB Brucella suis VBI22 acetolactate synthase 3 catalytic subunit YP_005155058.1 1343044 R 1112912 CDS YP_005155059.1 376281053 11728982 complement(1345115..1346047) 1 NC_016797.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1346047 miaA 11728982 miaA Brucella suis VBI22 tRNA delta(2)-isopentenylpyrophosphate transferase YP_005155059.1 1345115 R 1112912 CDS YP_005155060.1 376281054 11728983 1346065..1346964 1 NC_016797.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488; phosphoserine phosphatase 1346964 serB 11728983 serB Brucella suis VBI22 phosphoserine phosphatase YP_005155060.1 1346065 D 1112912 CDS YP_005155061.1 376281055 11728984 complement(1347005..1348186) 1 NC_016797.1 identified by similarity to OMNI:CC1477; match to protein family HMM PF03486; match to protein family HMM TIGR00275; hypothetical protein 1348186 11728984 BSVBI22_A1386 Brucella suis VBI22 hypothetical protein YP_005155061.1 1347005 R 1112912 CDS YP_005155062.1 376281056 11728985 complement(1348162..1348305) 1 NC_016797.1 hypothetical protein 1348305 11728985 BSVBI22_A1387 Brucella suis VBI22 hypothetical protein YP_005155062.1 1348162 R 1112912 CDS YP_005155063.1 376281057 11728986 complement(1348316..1349890) 1 NC_016797.1 identified by similarity to OMNI:CC2758; match to protein family HMM PF00089; match to protein family HMM PF00595; serine protease Do 1349890 11728986 BSVBI22_A1388 Brucella suis VBI22 serine protease Do YP_005155063.1 1348316 R 1112912 CDS YP_005155064.1 376281058 11728987 complement(1350114..1350299) 1 NC_016797.1 identified by similarity to GP:14022214; hypothetical protein 1350299 11728987 BSVBI22_A1389 Brucella suis VBI22 hypothetical protein YP_005155064.1 1350114 R 1112912 CDS YP_005155065.1 376281059 11728988 complement(1350319..1351221) 1 NC_016797.1 identified by similarity to EGAD:9363; match to protein family HMM PF01145; match to protein family HMM TIGR01932; hflC protein 1351221 hflC 11728988 hflC Brucella suis VBI22 hflC protein YP_005155065.1 1350319 R 1112912 CDS YP_005155066.1 376281060 11728989 complement(1351221..1352369) 1 NC_016797.1 identified by similarity to SP:Q9KV09; match to protein family HMM PF01145; match to protein family HMM TIGR01933; hflK protein 1352369 hflK 11728989 hflK Brucella suis VBI22 hflK protein YP_005155066.1 1351221 R 1112912 CDS YP_005155067.1 376281061 11728990 complement(1352494..1353012) 1 NC_016797.1 identified by match to protein family HMM PF00186; dihydrofolate reductase 1353012 folA 11728990 folA Brucella suis VBI22 dihydrofolate reductase YP_005155067.1 1352494 R 1112912 CDS YP_005155068.1 376281062 11728991 complement(1353015..1353809) 1 NC_016797.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1353809 thyA 11728991 thyA Brucella suis VBI22 thymidylate synthase YP_005155068.1 1353015 R 1112912 CDS YP_005155069.1 376281063 11728992 complement(1353910..1354221) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1156; hypothetical protein 1354221 11728992 BSVBI22_A1394 Brucella suis VBI22 hypothetical protein YP_005155069.1 1353910 R 1112912 CDS YP_005155070.1 376281064 11728993 complement(1354794..1356005) 1 NC_016797.1 identified by match to protein family HMM PF00083; match to protein family HMM TIGR00710; Bcr/CflA subfamily drug resistance transporter 1356005 tcaB 11728993 tcaB Brucella suis VBI22 Bcr/CflA subfamily drug resistance transporter YP_005155070.1 1354794 R 1112912 CDS YP_005155071.1 376281065 11728994 complement(1356022..1356168) 1 NC_016797.1 hypothetical protein 1356168 11728994 BSVBI22_A1396 Brucella suis VBI22 hypothetical protein YP_005155071.1 1356022 R 1112912 CDS YP_005155072.1 376281066 11728995 1356300..1357025 1 NC_016797.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1357025 11728995 BSVBI22_A1397 Brucella suis VBI22 TetR family transcriptional regulator YP_005155072.1 1356300 D 1112912 CDS YP_005155073.1 376281067 11728996 1357106..1357675 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1160; hypothetical protein 1357675 11728996 BSVBI22_A1398 Brucella suis VBI22 hypothetical protein YP_005155073.1 1357106 D 1112912 CDS YP_005155074.1 376281068 11728997 1357788..1357964 1 NC_016797.1 hypothetical protein 1357964 11728997 BSVBI22_A1399 Brucella suis VBI22 hypothetical protein YP_005155074.1 1357788 D 1112912 CDS YP_005155075.1 376281069 11728998 1358056..1358256 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1161; hypothetical protein 1358256 11728998 BSVBI22_A1400 Brucella suis VBI22 hypothetical protein YP_005155075.1 1358056 D 1112912 CDS YP_005155076.1 376281070 11728999 1358253..1358504 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1162; hypothetical protein 1358504 11728999 BSVBI22_A1401 Brucella suis VBI22 hypothetical protein YP_005155076.1 1358253 D 1112912 CDS YP_005155077.1 376281071 11729000 complement(1358532..1362275) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1167; match to protein family HMM PF05170; hypothetical protein 1362275 11729000 BSVBI22_A1402 Brucella suis VBI22 hypothetical protein YP_005155077.1 1358532 R 1112912 CDS YP_005155078.1 376281072 11729001 complement(1362330..1362470) 1 NC_016797.1 hypothetical protein 1362470 11729001 BSVBI22_A1403 Brucella suis VBI22 hypothetical protein YP_005155078.1 1362330 R 1112912 CDS YP_005155079.1 376281073 11729002 complement(1362467..1363873) 1 NC_016797.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; oxidoreductase, FAD-binding protein 1363873 11729002 BSVBI22_A1404 Brucella suis VBI22 oxidoreductase, FAD-binding protein YP_005155079.1 1362467 R 1112912 CDS YP_005155080.1 376281074 11729003 complement(1363898..1364407) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3966; hypothetical protein 1364407 11729003 BSVBI22_A1405 Brucella suis VBI22 hypothetical protein YP_005155080.1 1363898 R 1112912 CDS YP_005155081.1 376281075 11729004 1364527..1365603 1 NC_016797.1 identified by similarity to OMNI:NTL01XF00279; serine/threonine protein kinase 1365603 11729004 BSVBI22_A1406 Brucella suis VBI22 serine/threonine protein kinase YP_005155081.1 1364527 D 1112912 CDS YP_005155082.1 376281076 11729005 1365662..1368238 1 NC_016797.1 identified by similarity to EGAD:14237; match to protein family HMM PF00580; DNA helicase II 1368238 11729005 BSVBI22_A1407 Brucella suis VBI22 DNA helicase II YP_005155082.1 1365662 D 1112912 CDS YP_005155083.1 376281077 11729006 complement(1368312..1368809) 1 NC_016797.1 identified by similarity to GP:14022272; hypothetical protein 1368809 11729006 BSVBI22_A1408 Brucella suis VBI22 hypothetical protein YP_005155083.1 1368312 R 1112912 CDS YP_005155084.1 376281078 11729007 complement(1368874..1369563) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1201; match to protein family HMM PF00132; antibiotic acetyltransferase 1369563 11729007 BSVBI22_A1409 Brucella suis VBI22 antibiotic acetyltransferase YP_005155084.1 1368874 R 1112912 CDS YP_005155085.1 376281079 11729008 1369672..1370262 1 NC_016797.1 identified by match to protein family HMM PF02630; SCO1/SenC family protein 1370262 11729008 BSVBI22_A1410 Brucella suis VBI22 SCO1/SenC family protein YP_005155085.1 1369672 D 1112912 CDS YP_005155086.1 376281080 11729009 1370300..1371157 1 NC_016797.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1371157 prmA 11729009 prmA Brucella suis VBI22 50S ribosomal protein L11 methyltransferase YP_005155086.1 1370300 D 1112912 CDS YP_005155087.1 376281081 11729010 1371223..1373049 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1206; match to protein family HMM PF00557; aminopeptidase P 1373049 11729010 BSVBI22_A1412 Brucella suis VBI22 aminopeptidase P YP_005155087.1 1371223 D 1112912 CDS YP_005155088.1 376281082 11729011 complement(1373050..1373754) 1 NC_016797.1 identified by similarity to GP:14022279; hypothetical protein 1373754 11729011 BSVBI22_A1413 Brucella suis VBI22 hypothetical protein YP_005155088.1 1373050 R 1112912 CDS YP_005155089.1 376281083 11729012 complement(1373754..1375913) 1 NC_016797.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1375913 ligA 11729012 ligA Brucella suis VBI22 NAD-dependent DNA ligase LigA YP_005155089.1 1373754 R 1112912 CDS YP_005155090.1 376281084 11729013 complement(1376099..1377778) 1 NC_016797.1 identified by similarity to SP:P05824; match to protein family HMM TIGR00634; DNA repair protein RecN 1377778 recN 11729013 recN Brucella suis VBI22 DNA repair protein RecN YP_005155090.1 1376099 R 1112912 CDS YP_005155091.1 376281085 11729014 complement(1377791..1378654) 1 NC_016797.1 identified by similarity to EGAD:40678; match to protein family HMM PF03696; competence protein ComL 1378654 11729014 BSVBI22_A1416 Brucella suis VBI22 competence protein ComL YP_005155091.1 1377791 R 1112912 CDS YP_005155092.1 376281086 11729015 1378738..1379001 1 NC_016797.1 hypothetical protein 1379001 11729015 BSVBI22_A1417 Brucella suis VBI22 hypothetical protein YP_005155092.1 1378738 D 1112912 CDS YP_005155093.1 376281087 11729016 complement(1379061..1379921) 1 NC_016797.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1379921 lpxC 11729016 lpxC Brucella suis VBI22 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_005155093.1 1379061 R 1112912 CDS YP_005155094.1 376281088 11729017 complement(1380461..1382161) 1 NC_016797.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1382161 ftsZ 11729017 ftsZ Brucella suis VBI22 cell division protein FtsZ YP_005155094.1 1380461 R 1112912 CDS YP_005155095.1 376281089 11729018 complement(1382258..1383580) 1 NC_016797.1 identified by similarity to SP:O30994; match to protein family HMM PF02491; match to protein family HMM TIGR01174; cell division protein FtsA 1383580 ftsA 11729018 ftsA Brucella suis VBI22 cell division protein FtsA YP_005155095.1 1382258 R 1112912 CDS YP_005155096.1 376281090 11729019 complement(1383577..1384443) 1 NC_016797.1 identified by similarity to SP:O30993; match to protein family HMM PF03799; cell division protein FtsQ 1384443 11729019 BSVBI22_A1421 Brucella suis VBI22 cell division protein FtsQ YP_005155096.1 1383577 R 1112912 CDS YP_005155097.1 376281091 11729020 complement(1384500..1385426) 1 NC_016797.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 1385426 ddl 11729020 ddl Brucella suis VBI22 D-alanine--D-alanine ligase YP_005155097.1 1384500 R 1112912 CDS YP_005155098.1 376281092 11729021 complement(1385669..1386637) 1 NC_016797.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1386637 murB 11729021 murB Brucella suis VBI22 UDP-N-acetylenolpyruvoylglucosamine reductase YP_005155098.1 1385669 R 1112912 CDS YP_005155099.1 376281093 11729022 complement(1386637..1388052) 1 NC_016797.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1388052 murC 11729022 murC Brucella suis VBI22 UDP-N-acetylmuramate--L-alanine ligase YP_005155099.1 1386637 R 1112912 CDS YP_005155100.1 376281094 11729023 complement(1388049..1389188) 1 NC_016797.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1389188 murG 11729023 murG Brucella suis VBI22 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_005155100.1 1388049 R 1112912 CDS YP_005155101.1 376281095 11729024 complement(1389415..1390572) 1 NC_016797.1 identified by similarity to EGAD:20048; match to protein family HMM PF01098; cell division protein FtsW 1390572 ftsW 11729024 ftsW Brucella suis VBI22 cell division protein FtsW YP_005155101.1 1389415 R 1112912 CDS YP_005155102.1 376281096 11729025 complement(1390572..1391975) 1 NC_016797.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1391975 murD 11729025 murD Brucella suis VBI22 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_005155102.1 1390572 R 1112912 CDS YP_005155103.1 376281097 11729026 complement(1391988..1393070) 1 NC_016797.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1393070 mraY 11729026 mraY Brucella suis VBI22 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_005155103.1 1391988 R 1112912 CDS YP_005155104.1 376281098 11729027 complement(1393097..1394542) 1 NC_016797.1 identified by similarity to EGAD:15807; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM TIGR01143; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanine ligase 1394542 murF 11729027 murF Brucella suis VBI22 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanine ligase YP_005155104.1 1393097 R 1112912 CDS YP_005155105.1 376281099 11729028 complement(1394539..1396005) 1 NC_016797.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1396005 murE 11729028 murE Brucella suis VBI22 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_005155105.1 1394539 R 1112912 CDS YP_005155106.1 376281100 11729029 complement(1396066..1397889) 1 NC_016797.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin-binding protein 1397889 11729029 BSVBI22_A1431 Brucella suis VBI22 penicillin-binding protein YP_005155106.1 1396066 R 1112912 CDS YP_005155107.1 376281101 11729030 complement(1397892..1398293) 1 NC_016797.1 identified by similarity to GP:14022298; hypothetical protein 1398293 11729030 BSVBI22_A1432 Brucella suis VBI22 hypothetical protein YP_005155107.1 1397892 R 1112912 CDS YP_005155108.1 376281102 11729031 complement(1398298..1399338) 1 NC_016797.1 identified by similarity to GP:15075206; match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 1399338 mraW 11729031 mraW Brucella suis VBI22 S-adenosyl-methyltransferase MraW YP_005155108.1 1398298 R 1112912 CDS YP_005155109.1 376281103 11729032 1399316..1399585 1 NC_016797.1 hypothetical protein 1399585 11729032 BSVBI22_A1434 Brucella suis VBI22 hypothetical protein YP_005155109.1 1399316 D 1112912 CDS YP_005155110.1 376281104 11729033 1399812..1401182 1 NC_016797.1 identified by similarity to GP:17740175; match to protein family HMM PF01566; match to protein family HMM TIGR01197; manganese transport protein MntH 1401182 11729033 BSVBI22_A1435 Brucella suis VBI22 manganese transport protein MntH YP_005155110.1 1399812 D 1112912 CDS YP_005155111.1 376281105 11729034 1401375..1401887 1 NC_016797.1 hypothetical protein 1401887 11729034 BSVBI22_A1436 Brucella suis VBI22 hypothetical protein YP_005155111.1 1401375 D 1112912 CDS YP_005155112.1 376281106 11729035 complement(1401884..1402528) 1 NC_016797.1 identified by match to protein family HMM PF01464; transglycosylase 1402528 11729035 BSVBI22_A1437 Brucella suis VBI22 transglycosylase YP_005155112.1 1401884 R 1112912 CDS YP_005155113.1 376281107 11729036 complement(1402869..1403675) 1 NC_016797.1 identified by match to protein family HMM PF01471; match to protein family HMM PF01510; N-acetylmuramoyl-L-alanine amidase 1403675 11729036 BSVBI22_A1438 Brucella suis VBI22 N-acetylmuramoyl-L-alanine amidase YP_005155113.1 1402869 R 1112912 CDS YP_005155114.1 376281108 11729037 complement(1403672..1404382) 1 NC_016797.1 identified by match to protein family HMM PF00226; DnaJ domain-containing protein 1404382 11729037 BSVBI22_A1439 Brucella suis VBI22 DnaJ domain-containing protein YP_005155114.1 1403672 R 1112912 CDS YP_005155115.1 376281109 11729038 complement(1404502..1404906) 1 NC_016797.1 hypothetical protein 1404906 11729038 BSVBI22_A1440 Brucella suis VBI22 hypothetical protein YP_005155115.1 1404502 R 1112912 CDS YP_005155116.1 376281110 11729039 1405210..1406043 1 NC_016797.1 identified by match to protein family HMM PF01183; glucosyl hydrolase family protein 1406043 11729039 BSVBI22_A1441 Brucella suis VBI22 glucosyl hydrolase family protein YP_005155116.1 1405210 D 1112912 CDS YP_005155117.1 376281111 11729042 complement(1408826..1409737) 1 NC_016797.1 identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; 5,10-methylenetetrahydrofolate reductase 1409737 metF 11729042 metF Brucella suis VBI22 5,10-methylenetetrahydrofolate reductase YP_005155117.1 1408826 R 1112912 CDS YP_005155118.1 376281112 11729043 complement(1409783..1410808) 1 NC_016797.1 identified by match to protein family HMM PF01022; match to protein family HMM PF01209; ArsR family transcriptional regulator 1410808 11729043 BSVBI22_A1445 Brucella suis VBI22 ArsR family transcriptional regulator YP_005155118.1 1409783 R 1112912 CDS YP_005155119.1 376281113 11729044 1410928..1411251 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1250; hypothetical protein 1411251 11729044 BSVBI22_A1446 Brucella suis VBI22 hypothetical protein YP_005155119.1 1410928 D 1112912 CDS YP_005155120.1 376281114 11729045 complement(1411306..1412631) 1 NC_016797.1 identified by match to protein family HMM PF00083; match to protein family HMM TIGR00883; metabolite-proton symporter 1412631 11729045 BSVBI22_A1447 Brucella suis VBI22 metabolite-proton symporter YP_005155120.1 1411306 R 1112912 CDS YP_005155121.1 376281115 11729046 1412639..1412893 1 NC_016797.1 hypothetical protein 1412893 11729046 BSVBI22_A1448 Brucella suis VBI22 hypothetical protein YP_005155121.1 1412639 D 1112912 CDS YP_005155122.1 376281116 11729047 complement(1413067..1413834) 1 NC_016797.1 identified by similarity to SP:P76145; trans-aconitate methyltransferase 1413834 tam 11729047 tam Brucella suis VBI22 trans-aconitate methyltransferase YP_005155122.1 1413067 R 1112912 CDS YP_005155123.1 376281117 11729048 complement(1413907..1415556) 1 NC_016797.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 1415556 11729048 BSVBI22_A1450 Brucella suis VBI22 putative ABC transporter ATP-binding protein YP_005155123.1 1413907 R 1112912 CDS YP_005155124.1 376281118 11729049 complement(1415636..1415815) 1 NC_016797.1 hypothetical protein 1415815 11729049 BSVBI22_A1451 Brucella suis VBI22 hypothetical protein YP_005155124.1 1415636 R 1112912 CDS YP_005155125.1 376281119 11729050 1416052..1416996 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1266; hypothetical protein 1416996 11729050 BSVBI22_A1452 Brucella suis VBI22 hypothetical protein YP_005155125.1 1416052 D 1112912 CDS YP_005155126.1 376281120 11729051 1417035..1417700 1 NC_016797.1 hypothetical protein 1417700 11729051 BSVBI22_A1453 Brucella suis VBI22 hypothetical protein YP_005155126.1 1417035 D 1112912 CDS YP_005155127.1 376281121 11729052 complement(1417794..1418480) 1 NC_016797.1 identified by similarity to OMNI:NTL01PM1376; hypothetical protein 1418480 11729052 BSVBI22_A1454 Brucella suis VBI22 hypothetical protein YP_005155127.1 1417794 R 1112912 CDS YP_005155128.1 376281122 11729053 1418861..1420078 1 NC_016797.1 identified by match to protein family HMM PF00355; Rieske 2Fe-2S family protein 1420078 11729053 BSVBI22_A1455 Brucella suis VBI22 Rieske 2Fe-2S family protein YP_005155128.1 1418861 D 1112912 CDS YP_005155129.1 376281123 11729054 1420112..1421230 1 NC_016797.1 identified by similarity to EGAD:91746; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; NADH oxidoreductase 1421230 11729054 BSVBI22_A1456 Brucella suis VBI22 NADH oxidoreductase YP_005155129.1 1420112 D 1112912 CDS YP_005155130.1 376281124 11729055 complement(1421244..1421453) 1 NC_016797.1 identified by similarity to SP:P16680; match to protein family HMM PF03831; phnA protein 1421453 11729055 BSVBI22_A1457 Brucella suis VBI22 phnA protein YP_005155130.1 1421244 R 1112912 CDS YP_005155131.1 376281125 11729056 1421591..1422220 1 NC_016797.1 identified by similarity to SP:P21369; match to protein family HMM PF00857; pyrazinamidase/nicotinamidase 1422220 pncA 11729056 pncA Brucella suis VBI22 pyrazinamidase/nicotinamidase YP_005155131.1 1421591 D 1112912 CDS YP_005155132.1 376281126 11729057 complement(1422217..1423278) 1 NC_016797.1 identified by match to protein family HMM PF04332; hypothetical protein 1423278 11729057 BSVBI22_A1459 Brucella suis VBI22 hypothetical protein YP_005155132.1 1422217 R 1112912 CDS YP_005155133.1 376281127 11729058 1423625..1423891 1 NC_016797.1 hypothetical protein 1423891 11729058 BSVBI22_A1460 Brucella suis VBI22 hypothetical protein YP_005155133.1 1423625 D 1112912 CDS YP_005155134.1 376281128 11729059 complement(1423847..1424026) 1 NC_016797.1 hypothetical protein 1424026 11729059 BSVBI22_A1461 Brucella suis VBI22 hypothetical protein YP_005155134.1 1423847 R 1112912 CDS YP_005155135.1 376281129 11729060 complement(1424089..1425090) 1 NC_016797.1 identified by match to protein family HMM PF02275; choloylglycine hydrolase family protein 1425090 11729060 BSVBI22_A1462 Brucella suis VBI22 choloylglycine hydrolase family protein YP_005155135.1 1424089 R 1112912 CDS YP_005155136.1 376281130 11729061 1425468..1426271 1 NC_016797.1 identified by similarity to GP:14523684; hypothetical protein 1426271 11729061 BSVBI22_A1463 Brucella suis VBI22 hypothetical protein YP_005155136.1 1425468 D 1112912 CDS YP_005155137.1 376281131 11729062 1426878..1427051 1 NC_016797.1 hypothetical protein 1427051 11729062 BSVBI22_A1464 Brucella suis VBI22 hypothetical protein YP_005155137.1 1426878 D 1112912 CDS YP_005155138.1 376281132 11729063 complement(1427105..1427332) 1 NC_016797.1 hypothetical protein 1427332 11729063 BSVBI22_A1465 Brucella suis VBI22 hypothetical protein YP_005155138.1 1427105 R 1112912 CDS YP_005155139.1 376281133 11729064 1427459..1427812 1 NC_016797.1 hypothetical protein 1427812 11729064 BSVBI22_A1466 Brucella suis VBI22 hypothetical protein YP_005155139.1 1427459 D 1112912 CDS YP_005155140.1 376281134 11729065 complement(1427973..1428545) 1 NC_016797.1 hypothetical protein 1428545 11729065 BSVBI22_A1467 Brucella suis VBI22 hypothetical protein YP_005155140.1 1427973 R 1112912 CDS YP_005155141.1 376281135 11729066 1428781..1429275 1 NC_016797.1 identified by match to protein family HMM PF00589; phage integrase family site specific recombinase 1429275 11729066 BSVBI22_A1468 Brucella suis VBI22 phage integrase family site specific recombinase YP_005155141.1 1428781 D 1112912 CDS YP_005155142.1 376281136 11729068 1429693..1430445 1 NC_016797.1 identified by similarity to EGAD:40996; match to protein family HMM PF04402; immunoreactive 28 kDa outer membrane protein 1430445 omp28 11729068 omp28 Brucella suis VBI22 immunoreactive 28 kDa outer membrane protein YP_005155142.1 1429693 D 1112912 CDS YP_005155143.1 376281137 11729069 complement(1430620..1430964) 1 NC_016797.1 hypothetical protein 1430964 11729069 BSVBI22_A1470 Brucella suis VBI22 hypothetical protein YP_005155143.1 1430620 R 1112912 CDS YP_005155144.1 376281138 11729070 complement(1431208..1431666) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1869; match to protein family HMM PF05779; hypothetical protein 1431666 11729070 BSVBI22_A1471 Brucella suis VBI22 hypothetical protein YP_005155144.1 1431208 R 1112912 CDS YP_005155145.1 376281139 11729071 complement(1431858..1432148) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML1900; hypothetical protein 1432148 11729071 BSVBI22_A1472 Brucella suis VBI22 hypothetical protein YP_005155145.1 1431858 R 1112912 CDS YP_005155146.1 376281140 11729072 complement(1432172..1434190) 1 NC_016797.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1434190 rpoD 11729072 rpoD Brucella suis VBI22 RNA polymerase sigma factor RpoD YP_005155146.1 1432172 R 1112912 CDS YP_005155147.1 376281141 11729073 complement(1434658..1436625) 1 NC_016797.1 synthesizes RNA primers at the replication forks; DNA primase 1436625 dnaG 11729073 dnaG Brucella suis VBI22 DNA primase YP_005155147.1 1434658 R 1112912 CDS YP_005155148.1 376281142 11729074 1436995..1438671 1 NC_016797.1 identified by match to protein family HMM PF02690; Na/Pi-cotransporter family protein 1438671 11729074 BSVBI22_A1475 Brucella suis VBI22 Na/Pi-cotransporter family protein YP_005155148.1 1436995 D 1112912 CDS YP_005155149.1 376281143 11729075 complement(1438738..1439190) 1 NC_016797.1 identified by similarity to GP:15075342; match to protein family HMM PF02637; hypothetical protein 1439190 11729075 BSVBI22_A1476 Brucella suis VBI22 hypothetical protein YP_005155149.1 1438738 R 1112912 CDS YP_005155150.1 376281144 11729076 1439570..1440793 1 NC_016797.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1440793 carA 11729076 carA Brucella suis VBI22 carbamoyl phosphate synthase small subunit YP_005155150.1 1439570 D 1112912 CDS YP_005155151.1 376281145 11729077 1440801..1440929 1 NC_016797.1 hypothetical protein 1440929 11729077 BSVBI22_A1478 Brucella suis VBI22 hypothetical protein YP_005155151.1 1440801 D 1112912 CDS YP_005155152.1 376281146 11729078 complement(1440965..1441891) 1 NC_016797.1 identified by similarity to GP:15074511; match to protein family HMM PF04228; hypothetical protein 1441891 11729078 BSVBI22_A1479 Brucella suis VBI22 hypothetical protein YP_005155152.1 1440965 R 1112912 CDS YP_005155153.1 376281147 11729079 complement(1442008..1442526) 1 NC_016797.1 identified by similarity to GP:15157321; hypothetical protein 1442526 11729079 BSVBI22_A1480 Brucella suis VBI22 hypothetical protein YP_005155153.1 1442008 R 1112912 CDS YP_005155154.1 376281148 11729080 1442540..1443412 1 NC_016797.1 identified by similarity to GP:15157322; match to protein family HMM PF04397; hypothetical protein 1443412 11729080 BSVBI22_A1481 Brucella suis VBI22 hypothetical protein YP_005155154.1 1442540 D 1112912 CDS YP_005155155.1 376281149 11729081 1443647..1447135 1 NC_016797.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1447135 carB 11729081 carB Brucella suis VBI22 carbamoyl phosphate synthase large subunit YP_005155155.1 1443647 D 1112912 CDS YP_005155156.1 376281150 11729082 1447456..1447794 1 NC_016797.1 hypothetical protein 1447794 11729082 BSVBI22_A1483 Brucella suis VBI22 hypothetical protein YP_005155156.1 1447456 D 1112912 CDS YP_005155157.1 376281151 11729083 complement(1447852..1449717) 1 NC_016797.1 identified by similarity to GP:2808503; transporter 1449717 11729083 BSVBI22_A1484 Brucella suis VBI22 transporter YP_005155157.1 1447852 R 1112912 CDS YP_005155158.1 376281152 11729084 1449907..1450368 1 NC_016797.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 1450368 11729084 BSVBI22_A1485 Brucella suis VBI22 MutT/nudix family protein YP_005155158.1 1449907 D 1112912 CDS YP_005155159.1 376281153 11729085 1450561..1450770 1 NC_016797.1 identified by similarity to SP:Q9Z3S6; match to protein family HMM PF00313; cold-shock family protein 1450770 11729085 BSVBI22_A1486 Brucella suis VBI22 cold-shock family protein YP_005155159.1 1450561 D 1112912 CDS YP_005155160.1 376281154 11729086 complement(1450900..1451511) 1 NC_016797.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase family protein 1451511 11729086 BSVBI22_A1487 Brucella suis VBI22 glutathione S-transferase family protein YP_005155160.1 1450900 R 1112912 CDS YP_005155161.1 376281155 11729087 complement(1451634..1451762) 1 NC_016797.1 hypothetical protein 1451762 11729087 BSVBI22_A1488 Brucella suis VBI22 hypothetical protein YP_005155161.1 1451634 R 1112912 CDS YP_005155162.1 376281156 11729088 1451761..1452963 1 NC_016797.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1452963 aspC 11729088 aspC Brucella suis VBI22 aspartate aminotransferase YP_005155162.1 1451761 D 1112912 CDS YP_005155163.1 376281157 11729089 1452983..1453168 1 NC_016797.1 hypothetical protein 1453168 11729089 BSVBI22_A1490 Brucella suis VBI22 hypothetical protein YP_005155163.1 1452983 D 1112912 CDS YP_005155164.1 376281158 11729090 1453165..1453380 1 NC_016797.1 hypothetical protein 1453380 11729090 BSVBI22_A1491 Brucella suis VBI22 hypothetical protein YP_005155164.1 1453165 D 1112912 CDS YP_005155165.1 376281159 11729091 complement(1453432..1454337) 1 NC_016797.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1454337 11729091 BSVBI22_A1492 Brucella suis VBI22 LysR family transcriptional regulator YP_005155165.1 1453432 R 1112912 CDS YP_005155166.1 376281160 11729092 complement(1454408..1455382) 1 NC_016797.1 identified by similarity to SP:P09625; match to protein family HMM PF00070; match to protein family HMM TIGR01292; thioredoxin reductase 1455382 trxB 11729092 trxB Brucella suis VBI22 thioredoxin reductase YP_005155166.1 1454408 R 1112912 CDS YP_005155167.1 376281161 11729093 1455704..1457104 1 NC_016797.1 identified by similarity to GP:3288671; match to protein family HMM PF02386; cation transport protein 1457104 11729093 BSVBI22_A1494 Brucella suis VBI22 cation transport protein YP_005155167.1 1455704 D 1112912 CDS YP_005155168.1 376281162 11729094 1457111..1457275 1 NC_016797.1 hypothetical protein 1457275 11729094 BSVBI22_A1495 Brucella suis VBI22 hypothetical protein YP_005155168.1 1457111 D 1112912 CDS YP_005155169.1 376281163 11729095 1457362..1457832 1 NC_016797.1 identified by similarity to SP:P56901; match to protein family HMM PF01037; leucine-responsive regulatory protein 1457832 lrp-1 11729095 lrp-1 Brucella suis VBI22 leucine-responsive regulatory protein YP_005155169.1 1457362 D 1112912 CDS YP_005155170.1 376281164 11729096 complement(1457839..1458903) 1 NC_016797.1 identified by similarity to SP:O68547; match to protein family HMM PF00534; lipopolysaccharide core biosynthesis mannosyltransferase LpcC 1458903 lpcC 11729096 lpcC Brucella suis VBI22 lipopolysaccharide core biosynthesis mannosyltransferase LpcC YP_005155170.1 1457839 R 1112912 CDS YP_005155171.1 376281165 11729097 complement(1458910..1459383) 1 NC_016797.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1459383 greA 11729097 greA Brucella suis VBI22 transcription elongation factor GreA YP_005155171.1 1458910 R 1112912 CDS YP_005155172.1 376281166 11729098 complement(1459652..1460671) 1 NC_016797.1 identified by similarity to EGAD:91665; hypothetical protein 1460671 11729098 BSVBI22_A1499 Brucella suis VBI22 hypothetical protein YP_005155172.1 1459652 R 1112912 CDS YP_005155173.1 376281167 11729099 complement(1460697..1460885) 1 NC_016797.1 hypothetical protein 1460885 11729099 BSVBI22_A1500 Brucella suis VBI22 hypothetical protein YP_005155173.1 1460697 R 1112912 CDS YP_005155174.1 376281168 11729100 1460863..1461774 1 NC_016797.1 identified by match to protein family HMM PF00892; hypothetical protein 1461774 11729100 BSVBI22_A1501 Brucella suis VBI22 hypothetical protein YP_005155174.1 1460863 D 1112912 CDS YP_005155175.1 376281169 11729101 complement(1461779..1462129) 1 NC_016797.1 identified by match to protein family HMM PF04342; hypothetical protein 1462129 11729101 BSVBI22_A1502 Brucella suis VBI22 hypothetical protein YP_005155175.1 1461779 R 1112912 CDS YP_005155176.1 376281170 11729102 1462407..1463318 1 NC_016797.1 identified by similarity to GP:15074829; hypothetical protein 1463318 11729102 BSVBI22_A1503 Brucella suis VBI22 hypothetical protein YP_005155176.1 1462407 D 1112912 CDS YP_005155177.1 376281171 11729103 complement(1463451..1463840) 1 NC_016797.1 identified by match to protein family HMM PF03061; long-chain acyl-CoA thioester hydrolase 1463840 11729103 BSVBI22_A1504 Brucella suis VBI22 long-chain acyl-CoA thioester hydrolase YP_005155177.1 1463451 R 1112912 CDS YP_005155178.1 376281172 11729104 1464062..1464643 1 NC_016797.1 identified by similarity to GP:15162152; hypothetical protein 1464643 11729104 BSVBI22_A1505 Brucella suis VBI22 hypothetical protein YP_005155178.1 1464062 D 1112912 CDS YP_005155179.1 376281173 11729105 1464769..1467591 1 NC_016797.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1467591 uvrB 11729105 uvrB Brucella suis VBI22 excinuclease ABC subunit B YP_005155179.1 1464769 D 1112912 CDS YP_005155180.1 376281174 11729107 1469021..1469236 1 NC_016797.1 identified by match to protein family HMM PF00313; cold-shock family protein 1469236 11729107 BSVBI22_A1508 Brucella suis VBI22 cold-shock family protein YP_005155180.1 1469021 D 1112912 CDS YP_005155181.1 376281175 11729108 complement(1469474..1469593) 1 NC_016797.1 hypothetical protein 1469593 11729108 BSVBI22_A1509 Brucella suis VBI22 hypothetical protein YP_005155181.1 1469474 R 1112912 CDS YP_005155182.1 376281176 11729109 1469653..1470162 1 NC_016797.1 identified by similarity to GP:15075354; hypothetical protein 1470162 11729109 BSVBI22_A1510 Brucella suis VBI22 hypothetical protein YP_005155182.1 1469653 D 1112912 CDS YP_005155183.1 376281177 11729110 complement(1470221..1470877) 1 NC_016797.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase family protein 1470877 11729110 BSVBI22_A1511 Brucella suis VBI22 metallo-beta-lactamase family protein YP_005155183.1 1470221 R 1112912 CDS YP_005155184.1 376281178 11729111 complement(1471091..1471372) 1 NC_016797.1 hypothetical protein 1471372 11729111 BSVBI22_A1512 Brucella suis VBI22 hypothetical protein YP_005155184.1 1471091 R 1112912 CDS YP_005155185.1 376281179 11729112 1471544..1471843 1 NC_016797.1 hypothetical protein 1471843 11729112 BSVBI22_A1513 Brucella suis VBI22 hypothetical protein YP_005155185.1 1471544 D 1112912 CDS YP_005155186.1 376281180 11729113 1471894..1472433 1 NC_016797.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1472433 11729113 BSVBI22_A1514 Brucella suis VBI22 MarR family transcriptional regulator YP_005155186.1 1471894 D 1112912 CDS YP_005155187.1 376281181 11729114 1472515..1473240 1 NC_016797.1 identified by similarity to EGAD:19467; match to protein family HMM PF00072; match to protein family HMM PF00486; transcriptional regulator OmpR 1473240 11729114 BSVBI22_A1515 Brucella suis VBI22 transcriptional regulator OmpR YP_005155187.1 1472515 D 1112912 CDS YP_005155188.1 376281182 11729115 1473429..1474727 1 NC_016797.1 identified by similarity to EGAD:163236; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; osmolarity sensor protein EnvZ 1474727 11729115 BSVBI22_A1516 Brucella suis VBI22 osmolarity sensor protein EnvZ YP_005155188.1 1473429 D 1112912 CDS YP_005155189.1 376281183 11729116 complement(1475059..1475178) 1 NC_016797.1 hypothetical protein 1475178 11729116 BSVBI22_A1517 Brucella suis VBI22 hypothetical protein YP_005155189.1 1475059 R 1112912 CDS YP_005155190.1 376281184 11729117 complement(1475159..1475506) 1 NC_016797.1 identified by similarity to SP:P37584; match to protein family HMM PF01588; csaA protein 1475506 csaA 11729117 csaA Brucella suis VBI22 csaA protein YP_005155190.1 1475159 R 1112912 CDS YP_005155191.1 376281185 11729118 complement(1475645..1476307) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2065; hypothetical protein 1476307 11729118 BSVBI22_A1519 Brucella suis VBI22 hypothetical protein YP_005155191.1 1475645 R 1112912 CDS YP_005155192.1 376281186 11729119 complement(1476574..1476894) 1 NC_016797.1 identified by similarity to GP:15075365; match to protein family HMM PF04380; hypothetical protein 1476894 11729119 BSVBI22_A1520 Brucella suis VBI22 hypothetical protein YP_005155192.1 1476574 R 1112912 CDS YP_005155193.1 376281187 11729120 complement(1476912..1477064) 1 NC_016797.1 hypothetical protein 1477064 11729120 BSVBI22_A1521 Brucella suis VBI22 hypothetical protein YP_005155193.1 1476912 R 1112912 CDS YP_005155194.1 376281188 11729121 1477079..1477924 1 NC_016797.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1477924 lgt 11729121 lgt Brucella suis VBI22 prolipoprotein diacylglyceryl transferase YP_005155194.1 1477079 D 1112912 CDS YP_005155195.1 376281189 11729122 1477917..1479014 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2069; match to protein family HMM PF02636; hypothetical protein 1479014 11729122 BSVBI22_A1523 Brucella suis VBI22 hypothetical protein YP_005155195.1 1477917 D 1112912 CDS YP_005155196.1 376281190 11729123 1479194..1480045 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2070; match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein 1480045 11729123 BSVBI22_A1524 Brucella suis VBI22 hypothetical protein YP_005155196.1 1479194 D 1112912 CDS YP_005155197.1 376281191 11729124 1480158..1481309 1 NC_016797.1 identified by match to protein family HMM PF00557; M24 family peptidase 1481309 11729124 BSVBI22_A1525 Brucella suis VBI22 M24 family peptidase YP_005155197.1 1480158 D 1112912 CDS YP_005155198.1 376281192 11729125 1481363..1481917 1 NC_016797.1 identified by similarity to GP:15075370; putative lipoprotein 1481917 11729125 BSVBI22_A1526 Brucella suis VBI22 putative lipoprotein YP_005155198.1 1481363 D 1112912 CDS YP_005155199.1 376281193 11729126 1482256..1483188 1 NC_016797.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1483188 prsA 11729126 prsA Brucella suis VBI22 ribose-phosphate pyrophosphokinase YP_005155199.1 1482256 D 1112912 CDS YP_005155200.1 376281194 11729127 complement(1483336..1484877) 1 NC_016797.1 identified by similarity to GP:15074722; hypothetical protein 1484877 11729127 BSVBI22_A1528 Brucella suis VBI22 hypothetical protein YP_005155200.1 1483336 R 1112912 CDS YP_005155201.1 376281195 11729128 1485569..1486192 1 NC_016797.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 1486192 11729128 BSVBI22_A1529 Brucella suis VBI22 50S ribosomal protein L25/general stress protein Ctc YP_005155201.1 1485569 D 1112912 CDS YP_005155202.1 376281196 11729129 1486221..1486973 1 NC_016797.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1486973 pth 11729129 pth Brucella suis VBI22 peptidyl-tRNA hydrolase YP_005155202.1 1486221 D 1112912 CDS YP_005155203.1 376281197 11729130 1487061..1488164 1 NC_016797.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1488164 11729130 BSVBI22_A1531 Brucella suis VBI22 GTP-dependent nucleic acid-binding protein EngD YP_005155203.1 1487061 D 1112912 CDS YP_005155204.1 376281198 11729131 1488226..1488726 1 NC_016797.1 identified by match to protein family HMM PF01575; maoC-related protein 1488726 11729131 BSVBI22_A1532 Brucella suis VBI22 maoC-related protein YP_005155204.1 1488226 D 1112912 CDS YP_005155205.1 376281199 11729132 1488723..1489205 1 NC_016797.1 identified by match to protein family HMM PF01575; maoC-related protein 1489205 11729132 BSVBI22_A1533 Brucella suis VBI22 maoC-related protein YP_005155205.1 1488723 D 1112912 CDS YP_005155206.1 376281200 11729133 complement(1489247..1489807) 1 NC_016797.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1489807 apt 11729133 apt Brucella suis VBI22 adenine phosphoribosyltransferase YP_005155206.1 1489247 R 1112912 CDS YP_005155207.1 376281201 11729134 complement(1490115..1491002) 1 NC_016797.1 identified by match to protein family HMM PF02167; ubiquinol-cytochrome c reductase, cytochrome c1 1491002 11729134 BSVBI22_A1535 Brucella suis VBI22 ubiquinol-cytochrome c reductase, cytochrome c1 YP_005155207.1 1490115 R 1112912 CDS YP_005155208.1 376281202 11729135 complement(1491016..1492314) 1 NC_016797.1 identified by similarity to EGAD:46867; match to protein family HMM PF00032; match to protein family HMM PF00033; ubiquinol-cytochrome c reductase, cytochrome b 1492314 petB 11729135 petB Brucella suis VBI22 ubiquinol-cytochrome c reductase, cytochrome b YP_005155208.1 1491016 R 1112912 CDS YP_005155209.1 376281203 11729136 complement(1492336..1492899) 1 NC_016797.1 identified by similarity to EGAD:9907; match to protein family HMM PF00355; match to protein family HMM TIGR01409; match to protein family HMM TIGR01416; ubiquinol-cytochrome c reductase, iron-sulfur subunit 1492899 11729136 BSVBI22_A1537 Brucella suis VBI22 ubiquinol-cytochrome c reductase, iron-sulfur subunit YP_005155209.1 1492336 R 1112912 CDS YP_005155210.1 376281204 11729139 1497188..1497667 1 NC_016797.1 identified by match to protein family HMM PF00588; RNA methyltransferase 1497667 11729139 BSVBI22_A1540 Brucella suis VBI22 RNA methyltransferase YP_005155210.1 1497188 D 1112912 CDS YP_005155211.1 376281205 11729141 complement(1498817..1498918) 1 NC_016797.1 hypothetical protein 1498918 11729141 BSVBI22_A1542 Brucella suis VBI22 hypothetical protein YP_005155211.1 1498817 R 1112912 CDS YP_005155212.1 376281206 11729142 complement(1498926..1499186) 1 NC_016797.1 identified by similarity to GP:15074760; hypothetical protein 1499186 11729142 BSVBI22_A1543 Brucella suis VBI22 hypothetical protein YP_005155212.1 1498926 R 1112912 CDS YP_005155213.1 376281207 11729143 1499480..1500391 1 NC_016797.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1500391 hemF 11729143 hemF Brucella suis VBI22 coproporphyrinogen III oxidase YP_005155213.1 1499480 D 1112912 CDS YP_005155214.1 376281208 11729144 complement(1500425..1500919) 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 1500919 11729144 BSVBI22_A1545 Brucella suis VBI22 acetyltransferase YP_005155214.1 1500425 R 1112912 CDS YP_005155215.1 376281209 11729146 complement(1501952..1503223) 1 NC_016797.1 identified by match to protein family HMM PF01743; polyA polymerase family protein 1503223 11729146 BSVBI22_A1547 Brucella suis VBI22 polyA polymerase family protein YP_005155215.1 1501952 R 1112912 CDS YP_005155216.1 376281210 11729147 complement(1503220..1503726) 1 NC_016797.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 1503726 11729147 BSVBI22_A1548 Brucella suis VBI22 MutT/nudix family protein YP_005155216.1 1503220 R 1112912 CDS YP_005155217.1 376281211 11729148 complement(1503840..1504505) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2109; hypothetical protein 1504505 11729148 BSVBI22_A1549 Brucella suis VBI22 hypothetical protein YP_005155217.1 1503840 R 1112912 CDS YP_005155218.1 376281212 11729149 1504625..1505632 1 NC_016797.1 identified by similarity to GP:2689172; moxR protein 1505632 moxR 11729149 moxR Brucella suis VBI22 moxR protein YP_005155218.1 1504625 D 1112912 CDS YP_005155219.1 376281213 11729150 1505632..1506564 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2111; match to protein family HMM PF01882; hypothetical protein 1506564 11729150 BSVBI22_A1551 Brucella suis VBI22 hypothetical protein YP_005155219.1 1505632 D 1112912 CDS YP_005155220.1 376281214 11729151 1506561..1509410 1 NC_016797.1 hypothetical protein 1509410 11729151 BSVBI22_A1552 Brucella suis VBI22 hypothetical protein YP_005155220.1 1506561 D 1112912 CDS YP_005155221.1 376281215 11729152 1509474..1511549 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2113; hypothetical protein 1511549 11729152 BSVBI22_A1553 Brucella suis VBI22 hypothetical protein YP_005155221.1 1509474 D 1112912 CDS YP_005155222.1 376281216 11729153 complement(1511617..1512123) 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 1512123 11729153 BSVBI22_A1554 Brucella suis VBI22 acetyltransferase YP_005155222.1 1511617 R 1112912 CDS YP_005155223.1 376281217 11729154 1512427..1513410 1 NC_016797.1 glutathione S-transferase domain-containing protein 1513410 11729154 BSVBI22_A1555 Brucella suis VBI22 glutathione S-transferase domain-containing protein YP_005155223.1 1512427 D 1112912 CDS YP_005155224.1 376281218 11729155 1513558..1514241 1 NC_016797.1 identified by match to protein family HMM PF03922; hypothetical protein 1514241 11729155 BSVBI22_A1556 Brucella suis VBI22 hypothetical protein YP_005155224.1 1513558 D 1112912 CDS YP_005155225.1 376281219 11729156 complement(1514275..1514730) 1 NC_016797.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 1514730 11729156 BSVBI22_A1557 Brucella suis VBI22 MutT/nudix family protein YP_005155225.1 1514275 R 1112912 CDS YP_005155226.1 376281220 11729157 1514839..1515741 1 NC_016797.1 identified by similarity to GP:14023230; match to protein family HMM PF00149; hypothetical protein 1515741 11729157 BSVBI22_A1558 Brucella suis VBI22 hypothetical protein YP_005155226.1 1514839 D 1112912 CDS YP_005155227.1 376281221 11729158 complement(1515735..1515863) 1 NC_016797.1 hypothetical protein 1515863 11729158 BSVBI22_A1559 Brucella suis VBI22 hypothetical protein YP_005155227.1 1515735 R 1112912 CDS YP_005155228.1 376281222 11729159 complement(1515942..1517609) 1 NC_016797.1 identified by match to protein family HMM PF00682; match to protein family HMM TIGR00970; 2-isopropylmalate synthase 1517609 leuA 11729159 leuA Brucella suis VBI22 2-isopropylmalate synthase YP_005155228.1 1515942 R 1112912 CDS YP_005155229.1 376281223 11729160 complement(1517801..1517959) 1 NC_016797.1 hypothetical protein 1517959 11729160 BSVBI22_A1561 Brucella suis VBI22 hypothetical protein YP_005155229.1 1517801 R 1112912 CDS YP_005155230.1 376281224 11729161 complement(1517974..1518882) 1 NC_016797.1 identified by similarity to GP:14023215; match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 1518882 11729161 BSVBI22_A1562 Brucella suis VBI22 cation efflux family protein YP_005155230.1 1517974 R 1112912 CDS YP_005155231.1 376281225 11729162 1518892..1519173 1 NC_016797.1 hypothetical protein 1519173 11729162 BSVBI22_A1563 Brucella suis VBI22 hypothetical protein YP_005155231.1 1518892 D 1112912 CDS YP_005155232.1 376281226 11729163 complement(1519352..1521547) 1 NC_016797.1 trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; anthranilate synthase 1521547 trpE 11729163 trpE Brucella suis VBI22 anthranilate synthase YP_005155232.1 1519352 R 1112912 CDS YP_005155233.1 376281227 11729164 1522226..1522687 1 NC_016797.1 identified by similarity to SP:P19494; match to protein family HMM PF01037; leucine-responsive regulatory protein 1522687 lrp-2 11729164 lrp-2 Brucella suis VBI22 leucine-responsive regulatory protein YP_005155233.1 1522226 D 1112912 CDS YP_005155234.1 376281228 11729165 1522828..1523238 1 NC_016797.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1523238 11729165 BSVBI22_A1566 Brucella suis VBI22 MarR family transcriptional regulator YP_005155234.1 1522828 D 1112912 CDS YP_005155235.1 376281229 11729166 1523333..1524625 1 NC_016797.1 identified by similarity to GP:17430574; transporter 1524625 11729166 BSVBI22_A1567 Brucella suis VBI22 transporter YP_005155235.1 1523333 D 1112912 CDS YP_005155236.1 376281230 11729167 complement(1524620..1525585) 1 NC_016797.1 identified by similarity to GP:14027266; hypothetical protein 1525585 11729167 BSVBI22_A1568 Brucella suis VBI22 hypothetical protein YP_005155236.1 1524620 R 1112912 CDS YP_005155237.1 376281231 11729168 complement(1525591..1526787) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2131; hypothetical protein 1526787 11729168 BSVBI22_A1569 Brucella suis VBI22 hypothetical protein YP_005155237.1 1525591 R 1112912 CDS YP_005155238.1 376281232 11729169 complement(1526784..1526933) 1 NC_016797.1 hypothetical protein 1526933 11729169 BSVBI22_A1570 Brucella suis VBI22 hypothetical protein YP_005155238.1 1526784 R 1112912 CDS YP_005155239.1 376281233 11729170 complement(1526917..1527042) 1 NC_016797.1 hypothetical protein 1527042 11729170 BSVBI22_A1571 Brucella suis VBI22 hypothetical protein YP_005155239.1 1526917 R 1112912 CDS YP_005155240.1 376281234 11729171 1527019..1527138 1 NC_016797.1 hypothetical protein 1527138 11729171 BSVBI22_A1572 Brucella suis VBI22 hypothetical protein YP_005155240.1 1527019 D 1112912 CDS YP_005155241.1 376281235 11729172 1527223..1528191 1 NC_016797.1 identified by similarity to GP:19880073; match to protein family HMM PF04069; glycine betaine/L-proline ABC transporter substrate-binding protein 1528191 11729172 BSVBI22_A1573 Brucella suis VBI22 glycine betaine/L-proline ABC transporter substrate-binding protein YP_005155241.1 1527223 D 1112912 CDS YP_005155242.1 376281236 11729173 1528280..1529116 1 NC_016797.1 identified by similarity to GP:17982347; match to protein family HMM PF00528; glycine betaine/L-proline ABC transporter permease 1529116 11729173 BSVBI22_A1574 Brucella suis VBI22 glycine betaine/L-proline ABC transporter permease YP_005155242.1 1528280 D 1112912 CDS YP_005155243.1 376281237 11729174 1529286..1530332 1 NC_016797.1 identified by similarity to SP:P46920; match to protein family HMM PF00005; glycine betaine/L-proline ABC transporter ATP-binding protein 1530332 11729174 BSVBI22_A1575 Brucella suis VBI22 glycine betaine/L-proline ABC transporter ATP-binding protein YP_005155243.1 1529286 D 1112912 CDS YP_005155244.1 376281238 11729175 complement(1530606..1531454) 1 NC_016797.1 identified by similarity to SP:P37313; match to protein family HMM PF00005; dipeptide ABC transporter ATP-binding protein 1531454 11729175 BSVBI22_A1576 Brucella suis VBI22 dipeptide ABC transporter ATP-binding protein YP_005155244.1 1530606 R 1112912 CDS YP_005155245.1 376281239 11729176 complement(1531451..1532299) 1 NC_016797.1 identified by similarity to SP:P37314; match to protein family HMM PF00005; dipeptide ABC transporter ATP-binding protein 1532299 11729176 BSVBI22_A1577 Brucella suis VBI22 dipeptide ABC transporter ATP-binding protein YP_005155245.1 1531451 R 1112912 CDS YP_005155246.1 376281240 11729177 complement(1532305..1533186) 1 NC_016797.1 identified by similarity to SP:P94312; match to protein family HMM PF00528; dipeptide ABC transporter permease 1533186 11729177 BSVBI22_A1578 Brucella suis VBI22 dipeptide ABC transporter permease YP_005155246.1 1532305 R 1112912 CDS YP_005155247.1 376281241 11729178 complement(1533194..1534201) 1 NC_016797.1 identified by similarity to SP:P94311; match to protein family HMM PF00528; dipeptide ABC transporter permease 1534201 11729178 BSVBI22_A1579 Brucella suis VBI22 dipeptide ABC transporter permease YP_005155247.1 1533194 R 1112912 CDS YP_005155248.1 376281242 11729180 1536239..1536544 1 NC_016797.1 hypothetical protein 1536544 11729180 BSVBI22_A1581 Brucella suis VBI22 hypothetical protein YP_005155248.1 1536239 D 1112912 CDS YP_005155249.1 376281243 11729181 complement(1536785..1537012) 1 NC_016797.1 hypothetical protein 1537012 11729181 BSVBI22_A1582 Brucella suis VBI22 hypothetical protein YP_005155249.1 1536785 R 1112912 CDS YP_005155250.1 376281244 11729182 1537002..1537349 1 NC_016797.1 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 1537349 11729182 BSVBI22_A1583 Brucella suis VBI22 ArsR family transcriptional regulator YP_005155250.1 1537002 D 1112912 CDS YP_005155251.1 376281245 11729183 1537379..1538209 1 NC_016797.1 identified by match to protein family HMM PF00588; RNA methyltransferase 1538209 11729183 BSVBI22_A1584 Brucella suis VBI22 RNA methyltransferase YP_005155251.1 1537379 D 1112912 CDS YP_005155252.1 376281246 11729184 complement(1538431..1539627) 1 NC_016797.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1539627 mnmA 11729184 mnmA Brucella suis VBI22 tRNA-specific 2-thiouridylase MnmA YP_005155252.1 1538431 R 1112912 CDS YP_005155253.1 376281247 11729185 complement(1539665..1539823) 1 NC_016797.1 hypothetical protein 1539823 11729185 BSVBI22_A1586 Brucella suis VBI22 hypothetical protein YP_005155253.1 1539665 R 1112912 CDS YP_005155254.1 376281248 11729186 1539932..1540207 1 NC_016797.1 identified by similarity to GP:15075739; hypothetical protein 1540207 11729186 BSVBI22_A1587 Brucella suis VBI22 hypothetical protein YP_005155254.1 1539932 D 1112912 CDS YP_005155255.1 376281249 11729187 1540410..1540703 1 NC_016797.1 identified by similarity to GP:15075740; hypothetical protein 1540703 11729187 BSVBI22_A1588 Brucella suis VBI22 hypothetical protein YP_005155255.1 1540410 D 1112912 CDS YP_005155256.1 376281250 11729188 complement(1540751..1541686) 1 NC_016797.1 identified by similarity to GP:14023239; hypothetical protein 1541686 11729188 BSVBI22_A1589 Brucella suis VBI22 hypothetical protein YP_005155256.1 1540751 R 1112912 CDS YP_005155257.1 376281251 11729189 complement(1541916..1542512) 1 NC_016797.1 identified by similarity to GP:17740928; hypothetical protein 1542512 11729189 BSVBI22_A1590 Brucella suis VBI22 hypothetical protein YP_005155257.1 1541916 R 1112912 CDS YP_005155258.1 376281252 11729190 complement(1542782..1542925) 1 NC_016797.1 hypothetical protein 1542925 11729190 BSVBI22_A1591 Brucella suis VBI22 hypothetical protein YP_005155258.1 1542782 R 1112912 CDS YP_005155259.1 376281253 11729191 1542924..1543553 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2168; hypothetical protein 1543553 11729191 BSVBI22_A1592 Brucella suis VBI22 hypothetical protein YP_005155259.1 1542924 D 1112912 CDS YP_005155260.1 376281254 11729192 complement(1543666..1544364) 1 NC_016797.1 identified by similarity to EGAD:41053; match to protein family HMM PF00072; match to protein family HMM PF00486; cell cycle transcriptional regulator CtrA 1544364 ctrA 11729192 ctrA Brucella suis VBI22 cell cycle transcriptional regulator CtrA YP_005155260.1 1543666 R 1112912 CDS YP_005155261.1 376281255 11729193 1544895..1545287 1 NC_016797.1 identified by similarity to GP:15075741; hypothetical protein 1545287 11729193 BSVBI22_A1594 Brucella suis VBI22 hypothetical protein YP_005155261.1 1544895 D 1112912 CDS YP_005155262.1 376281256 11729194 complement(1545371..1546495) 1 NC_016797.1 identified by match to protein family HMM PF01041; DegT/DnrJ/EryC1/StrS family protein 1546495 11729194 BSVBI22_A1595 Brucella suis VBI22 DegT/DnrJ/EryC1/StrS family protein YP_005155262.1 1545371 R 1112912 CDS YP_005155263.1 376281257 11729195 complement(1546655..1547611) 1 NC_016797.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 1547611 11729195 BSVBI22_A1596 Brucella suis VBI22 Gfo/Idh/MocA family oxidoreductase YP_005155263.1 1546655 R 1112912 CDS YP_005155264.1 376281258 11729196 complement(1547617..1547742) 1 NC_016797.1 hypothetical protein 1547742 11729196 BSVBI22_A1597 Brucella suis VBI22 hypothetical protein YP_005155264.1 1547617 R 1112912 CDS YP_005155265.1 376281259 11729198 1548013..1548267 1 NC_016797.1 hypothetical protein 1548267 11729198 BSVBI22_A1598 Brucella suis VBI22 hypothetical protein YP_005155265.1 1548013 D 1112912 CDS YP_005155266.1 376281260 11729199 complement(1548443..1549225) 1 NC_016797.1 identified by match to protein family HMM PF01755; glycosyl transferase family protein 1549225 11729199 BSVBI22_A1599 Brucella suis VBI22 glycosyl transferase family protein YP_005155266.1 1548443 R 1112912 CDS YP_005155267.1 376281261 11729201 1549970..1553077 1 NC_016797.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase 1553077 11729201 BSVBI22_A1600 Brucella suis VBI22 sensory box histidine kinase YP_005155267.1 1549970 D 1112912 CDS YP_005155268.1 376281262 11729202 complement(1553297..1553428) 1 NC_016797.1 hypothetical protein 1553428 11729202 BSVBI22_A1601 Brucella suis VBI22 hypothetical protein YP_005155268.1 1553297 R 1112912 CDS YP_005155269.1 376281263 11729203 1553818..1555755 1 NC_016797.1 identified by similarity to EGAD:20142; match to protein family HMM PF05170; AsmA family protein 1555755 11729203 BSVBI22_A1602 Brucella suis VBI22 AsmA family protein YP_005155269.1 1553818 D 1112912 CDS YP_005155270.1 376281264 11729204 complement(1555763..1556584) 1 NC_016797.1 identified by similarity to GP:16502083; match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1556584 11729204 BSVBI22_A1603 Brucella suis VBI22 spermidine/putrescine ABC transporter permease YP_005155270.1 1555763 R 1112912 CDS YP_005155271.1 376281265 11729205 complement(1556586..1557497) 1 NC_016797.1 identified by similarity to SP:P23860; match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1557497 11729205 BSVBI22_A1604 Brucella suis VBI22 spermidine/putrescine ABC transporter permease YP_005155271.1 1556586 R 1112912 CDS YP_005155272.1 376281266 11729206 complement(1557513..1558658) 1 NC_016797.1 identified by similarity to SP:P31134; match to protein family HMM PF00005; match to protein family HMM TIGR01187; spermidine/putrescine ABC transporter ATP-binding protein 1558658 11729206 BSVBI22_A1605 Brucella suis VBI22 spermidine/putrescine ABC transporter ATP-binding protein YP_005155272.1 1557513 R 1112912 CDS YP_005155273.1 376281267 11729207 complement(1558900..1560003) 1 NC_016797.1 identified by similarity to GP:15979381; match to protein family HMM PF01547; spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein 1560003 11729207 BSVBI22_A1606 Brucella suis VBI22 spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein YP_005155273.1 1558900 R 1112912 CDS YP_005155274.1 376281268 11729208 complement(1560225..1561637) 1 NC_016797.1 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 1561637 11729208 BSVBI22_A1607 Brucella suis VBI22 Cro/CI family transcriptional regulator YP_005155274.1 1560225 R 1112912 CDS YP_005155275.1 376281269 11729209 1561886..1563175 1 NC_016797.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; isocitrate lyase 1563175 aceA 11729209 aceA Brucella suis VBI22 isocitrate lyase YP_005155275.1 1561886 D 1112912 CDS YP_005155276.1 376281270 11729210 1563210..1563446 1 NC_016797.1 identified by similarity to OMNI:NTL02ML5126; hypothetical protein 1563446 11729210 BSVBI22_A1609 Brucella suis VBI22 hypothetical protein YP_005155276.1 1563210 D 1112912 CDS YP_005155277.1 376281271 11729211 1563443..1563571 1 NC_016797.1 hypothetical protein 1563571 11729211 BSVBI22_A1610 Brucella suis VBI22 hypothetical protein YP_005155277.1 1563443 D 1112912 CDS YP_005155278.1 376281272 11729212 complement(1563555..1563710) 1 NC_016797.1 hypothetical protein 1563710 11729212 BSVBI22_A1611 Brucella suis VBI22 hypothetical protein YP_005155278.1 1563555 R 1112912 CDS YP_005155279.1 376281273 11729214 1564408..1565175 1 NC_016797.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1565175 11729214 BSVBI22_A1612 Brucella suis VBI22 7-alpha-hydroxysteroid dehydrogenase YP_005155279.1 1564408 D 1112912 CDS YP_005155280.1 376281274 11729215 1565241..1566035 1 NC_016797.1 identified by similarity to EGAD:23950; match to protein family HMM PF00106; 7-alpha-hydroxysteroid dehydrogenase 1566035 11729215 BSVBI22_A1613 Brucella suis VBI22 7-alpha-hydroxysteroid dehydrogenase YP_005155280.1 1565241 D 1112912 CDS YP_005155281.1 376281275 11729216 1566045..1567802 1 NC_016797.1 hypothetical protein 1567802 11729216 BSVBI22_A1614 Brucella suis VBI22 hypothetical protein YP_005155281.1 1566045 D 1112912 CDS YP_005155282.1 376281276 11729217 1567830..1568432 1 NC_016797.1 identified by similarity to EGAD:10584; match to protein family HMM PF01914; hypothetical protein 1568432 11729217 BSVBI22_A1615 Brucella suis VBI22 hypothetical protein YP_005155282.1 1567830 D 1112912 CDS YP_005155283.1 376281277 11729218 1568711..1569496 1 NC_016797.1 identified by similarity to EGAD:150060; match to protein family HMM PF01389; outer membrane protein Omp31 1569496 omp31-1 11729218 omp31-1 Brucella suis VBI22 outer membrane protein Omp31 YP_005155283.1 1568711 D 1112912 CDS YP_005155284.1 376281278 11729219 complement(1569633..1571183) 1 NC_016797.1 hypothetical protein 1571183 11729219 BSVBI22_A1617 Brucella suis VBI22 hypothetical protein YP_005155284.1 1569633 R 1112912 CDS YP_005155285.1 376281279 11729220 1571304..1571393 1 NC_016797.1 hypothetical protein 1571393 11729220 BSVBI22_A1618 Brucella suis VBI22 hypothetical protein YP_005155285.1 1571304 D 1112912 CDS YP_005155286.1 376281280 11729221 complement(1571484..1571585) 1 NC_016797.1 hypothetical protein 1571585 11729221 BSVBI22_A1619 Brucella suis VBI22 hypothetical protein YP_005155286.1 1571484 R 1112912 CDS YP_005155287.1 376281281 11729222 1571736..1572017 1 NC_016797.1 hypothetical protein 1572017 11729222 BSVBI22_A1620 Brucella suis VBI22 hypothetical protein YP_005155287.1 1571736 D 1112912 CDS YP_005155288.1 376281282 11729225 complement(1576928..1577701) 1 NC_016797.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 1577701 11729225 BSVBI22_A1623 Brucella suis VBI22 short chain dehydrogenase YP_005155288.1 1576928 R 1112912 CDS YP_005155289.1 376281283 11729226 complement(1577790..1578779) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML0801; match to protein family HMM PF00532; LacI family transcriptional regulator 1578779 11729226 BSVBI22_A1624 Brucella suis VBI22 LacI family transcriptional regulator YP_005155289.1 1577790 R 1112912 CDS YP_005155290.1 376281284 11729227 complement(1578972..1579364) 1 NC_016797.1 IS711, transposase orfB 1579364 11729227 BSVBI22_A1625 Brucella suis VBI22 IS711, transposase orfB YP_005155290.1 1578972 R 1112912 CDS YP_005155291.1 376281285 11729228 complement(1579396..1579707) 1 NC_016797.1 IS711, transposase orfA 1579707 11729228 BSVBI22_A1626 Brucella suis VBI22 IS711, transposase orfA YP_005155291.1 1579396 R 1112912 CDS YP_005155292.1 376281286 11729229 complement(1579799..1580803) 1 NC_016797.1 identified by similarity to SP:P04984; match to protein family HMM PF02653; ribose ABC transporter permease 1580803 rbsC-2 11729229 rbsC-2 Brucella suis VBI22 ribose ABC transporter permease YP_005155292.1 1579799 R 1112912 CDS YP_005155293.1 376281287 11729230 complement(1580899..1582359) 1 NC_016797.1 identified by similarity to SP:P04983; match to protein family HMM PF00005; ribose ABC transporter ATP-binding protein 1582359 rbsA-2 11729230 rbsA-2 Brucella suis VBI22 ribose ABC transporter ATP-binding protein YP_005155293.1 1580899 R 1112912 CDS YP_005155294.1 376281288 11729231 1582539..1582676 1 NC_016797.1 hypothetical protein 1582676 11729231 BSVBI22_A1629 Brucella suis VBI22 hypothetical protein YP_005155294.1 1582539 D 1112912 CDS YP_005155295.1 376281289 11729232 1582673..1582990 1 NC_016797.1 hypothetical protein 1582990 11729232 BSVBI22_A1630 Brucella suis VBI22 hypothetical protein YP_005155295.1 1582673 D 1112912 CDS YP_005155296.1 376281290 11729233 complement(1583120..1583248) 1 NC_016797.1 hypothetical protein 1583248 11729233 BSVBI22_A1631 Brucella suis VBI22 hypothetical protein YP_005155296.1 1583120 R 1112912 CDS YP_005155297.1 376281291 11729237 1585656..1585808 1 NC_016797.1 hypothetical protein 1585808 11729237 BSVBI22_A1633 Brucella suis VBI22 hypothetical protein YP_005155297.1 1585656 D 1112912 CDS YP_005155298.1 376281292 11729239 1588763..1589005 1 NC_016797.1 hypothetical protein 1589005 11729239 BSVBI22_A1634 Brucella suis VBI22 hypothetical protein YP_005155298.1 1588763 D 1112912 CDS YP_005155299.1 376281293 11729243 complement(1591706..1592527) 1 NC_016797.1 identified by match to protein family HMM PF01614; IclR family transcriptional regulator 1592527 11729243 BSVBI22_A1635 Brucella suis VBI22 IclR family transcriptional regulator YP_005155299.1 1591706 R 1112912 CDS YP_005155300.1 376281294 11729244 1592645..1594096 1 NC_016797.1 identified by similarity to EGAD:16804; match to protein family HMM PF00171; match to protein family HMM TIGR01780; succinate-semialdehyde dehydrogenase 1594096 gabD 11729244 gabD Brucella suis VBI22 succinate-semialdehyde dehydrogenase YP_005155300.1 1592645 D 1112912 CDS YP_005155301.1 376281295 11729245 1594213..1594803 1 NC_016797.1 hypothetical protein 1594803 11729245 BSVBI22_A1637 Brucella suis VBI22 hypothetical protein YP_005155301.1 1594213 D 1112912 CDS YP_005155302.1 376281296 11729246 1594916..1595434 1 NC_016797.1 disulfide bond formation protein B 1595434 11729246 BSVBI22_A1638 Brucella suis VBI22 disulfide bond formation protein B YP_005155302.1 1594916 D 1112912 CDS YP_005155303.1 376281297 11729247 complement(1595451..1596023) 1 NC_016797.1 identified by match to protein family HMM PF01844; HNH endonuclease family protein 1596023 11729247 BSVBI22_A1639 Brucella suis VBI22 HNH endonuclease family protein YP_005155303.1 1595451 R 1112912 CDS YP_005155304.1 376281298 11729248 complement(1596020..1596112) 1 NC_016797.1 hypothetical protein 1596112 11729248 BSVBI22_A1640 Brucella suis VBI22 hypothetical protein YP_005155304.1 1596020 R 1112912 CDS YP_005155305.1 376281299 11729249 complement(1596174..1596281) 1 NC_016797.1 hypothetical protein 1596281 11729249 BSVBI22_A1641 Brucella suis VBI22 hypothetical protein YP_005155305.1 1596174 R 1112912 CDS YP_005155306.1 376281300 11729250 complement(1596297..1596995) 1 NC_016797.1 identified by match to protein family HMM PF00730; base-excision DNA repair protein 1596995 11729250 BSVBI22_A1642 Brucella suis VBI22 base-excision DNA repair protein YP_005155306.1 1596297 R 1112912 CDS YP_005155307.1 376281301 11729251 1597017..1597892 1 NC_016797.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 1597892 11729251 BSVBI22_A1643 Brucella suis VBI22 glutamyl-Q tRNA(Asp) synthetase YP_005155307.1 1597017 D 1112912 CDS YP_005155308.1 376281302 11729252 1598035..1600221 1 NC_016797.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 1600221 glcB 11729252 glcB Brucella suis VBI22 malate synthase G YP_005155308.1 1598035 D 1112912 CDS YP_005155309.1 376281303 11729253 1600526..1601020 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 1601020 11729253 BSVBI22_A1645 Brucella suis VBI22 acetyltransferase YP_005155309.1 1600526 D 1112912 CDS YP_005155310.1 376281304 11729254 complement(1601079..1601990) 1 NC_016797.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 1601990 11729254 BSVBI22_A1646 Brucella suis VBI22 RNA polymerase factor sigma-32 YP_005155310.1 1601079 R 1112912 CDS YP_005155311.1 376281305 11729255 complement(1602421..1603464) 1 NC_016797.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase D 1603464 11729255 BSVBI22_A1647 Brucella suis VBI22 ribosomal large subunit pseudouridine synthase D YP_005155311.1 1602421 R 1112912 CDS YP_005155312.1 376281306 11729256 1603481..1603957 1 NC_016797.1 hypothetical protein 1603957 11729256 BSVBI22_A1648 Brucella suis VBI22 hypothetical protein YP_005155312.1 1603481 D 1112912 CDS YP_005155313.1 376281307 11729257 1603991..1604164 1 NC_016797.1 hypothetical protein 1604164 11729257 BSVBI22_A1649 Brucella suis VBI22 hypothetical protein YP_005155313.1 1603991 D 1112912 CDS YP_005155314.1 376281308 11729259 1604336..1604761 1 NC_016797.1 identified by similarity to SP:O30976; match to protein family HMM PF01475; ferric uptake regulation protein 1604761 11729259 BSVBI22_A1650 Brucella suis VBI22 ferric uptake regulation protein YP_005155314.1 1604336 D 1112912 CDS YP_005155315.1 376281309 11729260 complement(1604997..1605932) 1 NC_016797.1 sensor histidine kinase 1605932 11729260 BSVBI22_A1651 Brucella suis VBI22 sensor histidine kinase YP_005155315.1 1604997 R 1112912 CDS YP_005155316.1 376281310 11729261 complement(1606200..1606409) 1 NC_016797.1 hypothetical protein 1606409 11729261 BSVBI22_A1652 Brucella suis VBI22 hypothetical protein YP_005155316.1 1606200 R 1112912 CDS YP_005155317.1 376281311 11729262 complement(1606514..1607308) 1 NC_016797.1 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media; two-component response regulator 1607308 11729262 BSVBI22_A1653 Brucella suis VBI22 two-component response regulator YP_005155317.1 1606514 R 1112912 CDS YP_005155318.1 376281312 11729263 1607755..1608327 1 NC_016797.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1608327 11729263 BSVBI22_A1654 Brucella suis VBI22 RNA polymerase sigma factor YP_005155318.1 1607755 D 1112912 CDS YP_005155319.1 376281313 11729264 1608528..1609958 1 NC_016797.1 identified by match to protein family HMM PF02518; match to protein family HMM PF05227; sensor histidine kinase 1609958 11729264 BSVBI22_A1655 Brucella suis VBI22 sensor histidine kinase YP_005155319.1 1608528 D 1112912 CDS YP_005155320.1 376281314 11729265 complement(1610019..1610450) 1 NC_016797.1 hypothetical protein 1610450 11729265 BSVBI22_A1656 Brucella suis VBI22 hypothetical protein YP_005155320.1 1610019 R 1112912 CDS YP_005155321.1 376281315 11729266 complement(1610459..1610812) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2854; hypothetical protein 1610812 11729266 BSVBI22_A1657 Brucella suis VBI22 hypothetical protein YP_005155321.1 1610459 R 1112912 CDS YP_005155322.1 376281316 11729267 complement(1610977..1611819) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2849; match to protein family HMM PF05239; hypothetical protein 1611819 11729267 BSVBI22_A1658 Brucella suis VBI22 hypothetical protein YP_005155322.1 1610977 R 1112912 CDS YP_005155323.1 376281317 11729268 complement(1611839..1611952) 1 NC_016797.1 hypothetical protein 1611952 11729268 BSVBI22_A1659 Brucella suis VBI22 hypothetical protein YP_005155323.1 1611839 R 1112912 CDS YP_005155324.1 376281318 11729269 complement(1611992..1612150) 1 NC_016797.1 hypothetical protein 1612150 11729269 BSVBI22_A1660 Brucella suis VBI22 hypothetical protein YP_005155324.1 1611992 R 1112912 CDS YP_005155325.1 376281319 11729270 1612281..1612484 1 NC_016797.1 hypothetical protein 1612484 11729270 BSVBI22_A1661 Brucella suis VBI22 hypothetical protein YP_005155325.1 1612281 D 1112912 CDS YP_005155326.1 376281320 11729271 1612646..1613524 1 NC_016797.1 identified by similarity to SP:P18783; match to protein family HMM PF01618; biopolymer transport protein ExbB 1613524 exbB 11729271 exbB Brucella suis VBI22 biopolymer transport protein ExbB YP_005155326.1 1612646 D 1112912 CDS YP_005155327.1 376281321 11729272 1613530..1614024 1 NC_016797.1 identified by similarity to SP:Q05606; match to protein family HMM PF02472; TonB system transport protein ExbD 1614024 11729272 BSVBI22_A1663 Brucella suis VBI22 TonB system transport protein ExbD YP_005155327.1 1613530 D 1112912 CDS YP_005155328.1 376281322 11729273 1614021..1614947 1 NC_016797.1 identified by match to protein family HMM TIGR01352; TonB-dependent receptor 1614947 11729273 BSVBI22_A1664 Brucella suis VBI22 TonB-dependent receptor YP_005155328.1 1614021 D 1112912 CDS YP_005155329.1 376281323 11729274 complement(1614990..1615760) 1 NC_016797.1 identified by similarity to GP:15074996; hypothetical protein 1615760 11729274 BSVBI22_A1665 Brucella suis VBI22 hypothetical protein YP_005155329.1 1614990 R 1112912 CDS YP_005155330.1 376281324 11729276 complement(1617734..1618960) 1 NC_016797.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; HlyD family secretion protein 1618960 11729276 BSVBI22_A1667 Brucella suis VBI22 HlyD family secretion protein YP_005155330.1 1617734 R 1112912 CDS YP_005155331.1 376281325 11729277 1619057..1619368 1 NC_016797.1 identified by similarity to EGAD:46813; IS711, transposase orfA 1619368 11729277 BSVBI22_A1668 Brucella suis VBI22 IS711, transposase orfA YP_005155331.1 1619057 D 1112912 CDS YP_005155332.1 376281326 11729278 1619400..1619792 1 NC_016797.1 identified by similarity to PIR:PN0685; match to protein family HMM PF01609; IS711, transposase orfB 1619792 11729278 BSVBI22_A1669 Brucella suis VBI22 IS711, transposase orfB YP_005155332.1 1619400 D 1112912 CDS YP_005155333.1 376281327 11729279 complement(1619806..1619931) 1 NC_016797.1 hypothetical protein 1619931 11729279 BSVBI22_A1670 Brucella suis VBI22 hypothetical protein YP_005155333.1 1619806 R 1112912 CDS YP_005155334.1 376281328 11729280 complement(1620039..1620512) 1 NC_016797.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1620512 dut 11729280 dut Brucella suis VBI22 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_005155334.1 1620039 R 1112912 CDS YP_005155335.1 376281329 11729281 complement(1620736..1621206) 1 NC_016797.1 identified by match to protein family HMM PF01037; match to protein family HMM TIGR01199; AsnC family transcriptional regulator 1621206 11729281 BSVBI22_A1672 Brucella suis VBI22 AsnC family transcriptional regulator YP_005155335.1 1620736 R 1112912 CDS YP_005155336.1 376281330 11729282 1621352..1621567 1 NC_016797.1 identified by similarity to OMNI:NTL02ML4136; hypothetical protein 1621567 11729282 BSVBI22_A1673 Brucella suis VBI22 hypothetical protein YP_005155336.1 1621352 D 1112912 CDS YP_005155337.1 376281331 11729283 1621607..1622470 1 NC_016797.1 identified by similarity to GP:13932326; match to protein family HMM PF00310; glutamine amidotransferase 1622470 11729283 BSVBI22_A1674 Brucella suis VBI22 glutamine amidotransferase YP_005155337.1 1621607 D 1112912 CDS YP_005155338.1 376281332 11729284 complement(1622497..1623480) 1 NC_016797.1 identified by match to protein family HMM PF01988; hypothetical protein 1623480 11729284 BSVBI22_A1675 Brucella suis VBI22 hypothetical protein YP_005155338.1 1622497 R 1112912 CDS YP_005155339.1 376281333 11729285 1623597..1625027 1 NC_016797.1 identified by match to protein family HMM PF00083; major facilitator family transporter 1625027 11729285 BSVBI22_A1676 Brucella suis VBI22 major facilitator family transporter YP_005155339.1 1623597 D 1112912 CDS YP_005155340.1 376281334 11729286 complement(1625237..1626634) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2989; hypothetical protein 1626634 11729286 BSVBI22_A1677 Brucella suis VBI22 hypothetical protein YP_005155340.1 1625237 R 1112912 CDS YP_005155341.1 376281335 11729287 complement(1626832..1626942) 1 NC_016797.1 hypothetical protein 1626942 11729287 BSVBI22_A1678 Brucella suis VBI22 hypothetical protein YP_005155341.1 1626832 R 1112912 CDS YP_005155342.1 376281336 11729288 complement(1626947..1628236) 1 NC_016797.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1628236 purA 11729288 purA Brucella suis VBI22 adenylosuccinate synthetase YP_005155342.1 1626947 R 1112912 CDS YP_005155343.1 376281337 11729289 complement(1628554..1629063) 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 1629063 11729289 BSVBI22_A1680 Brucella suis VBI22 acetyltransferase YP_005155343.1 1628554 R 1112912 CDS YP_005155344.1 376281338 11729290 complement(1629068..1630669) 1 NC_016797.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1630669 serA-1 11729290 serA-1 Brucella suis VBI22 D-3-phosphoglycerate dehydrogenase YP_005155344.1 1629068 R 1112912 CDS YP_005155345.1 376281339 11729291 complement(1630641..1630811) 1 NC_016797.1 hypothetical protein 1630811 11729291 BSVBI22_A1682 Brucella suis VBI22 hypothetical protein YP_005155345.1 1630641 R 1112912 CDS YP_005155346.1 376281340 11729292 complement(1630823..1631998) 1 NC_016797.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 1631998 serC 11729292 serC Brucella suis VBI22 phosphoserine aminotransferase YP_005155346.1 1630823 R 1112912 CDS YP_005155347.1 376281341 11729293 complement(1632149..1633105) 1 NC_016797.1 identified by match to protein family HMM PF01758; sodium/bile acid transporter family protein 1633105 11729293 BSVBI22_A1684 Brucella suis VBI22 sodium/bile acid transporter family protein YP_005155347.1 1632149 R 1112912 CDS YP_005155348.1 376281342 11729294 complement(1633286..1634110) 1 NC_016797.1 identified by similarity to GP:17742129; outer surface protein 1634110 11729294 BSVBI22_A1685 Brucella suis VBI22 outer surface protein YP_005155348.1 1633286 R 1112912 CDS YP_005155349.1 376281343 11729295 complement(1634295..1635650) 1 NC_016797.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; match to protein family HMM TIGR01455; phosphoglucosamine mutase 1635650 glmM 11729295 glmM Brucella suis VBI22 phosphoglucosamine mutase YP_005155349.1 1634295 R 1112912 CDS YP_005155350.1 376281344 11729296 complement(1635955..1637889) 1 NC_016797.1 identified by similarity to EGAD:13183; match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM TIGR01241; cell division protein FtsH 1637889 ftsH 11729296 ftsH Brucella suis VBI22 cell division protein FtsH YP_005155350.1 1635955 R 1112912 CDS YP_005155351.1 376281345 11729297 complement(1638025..1639371) 1 NC_016797.1 identified by similarity to GP:15075760; match to protein family HMM PF01171; hypothetical protein 1639371 11729297 BSVBI22_A1688 Brucella suis VBI22 hypothetical protein YP_005155351.1 1638025 R 1112912 CDS YP_005155352.1 376281346 11729298 complement(1639387..1640853) 1 NC_016797.1 hypothetical protein 1640853 11729298 BSVBI22_A1689 Brucella suis VBI22 hypothetical protein YP_005155352.1 1639387 R 1112912 CDS YP_005155353.1 376281347 11729299 complement(1640970..1641086) 1 NC_016797.1 hypothetical protein 1641086 11729299 BSVBI22_A1690 Brucella suis VBI22 hypothetical protein YP_005155353.1 1640970 R 1112912 CDS YP_005155354.1 376281348 11729300 complement(1641250..1641756) 1 NC_016797.1 identified by similarity to EGAD:9123; match to protein family HMM PF00691; Pal family lipoprotein 1641756 11729300 BSVBI22_A1691 Brucella suis VBI22 Pal family lipoprotein YP_005155354.1 1641250 R 1112912 CDS YP_005155355.1 376281349 11729301 complement(1641805..1641984) 1 NC_016797.1 hypothetical protein 1641984 11729301 BSVBI22_A1692 Brucella suis VBI22 hypothetical protein YP_005155355.1 1641805 R 1112912 CDS YP_005155356.1 376281350 11729302 complement(1642044..1643375) 1 NC_016797.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 1643375 tolB 11729302 tolB Brucella suis VBI22 translocation protein TolB YP_005155356.1 1642044 R 1112912 CDS YP_005155357.1 376281351 11729303 complement(1643431..1644501) 1 NC_016797.1 identified by similarity to GP:13898975; tolA protein 1644501 tolA 11729303 tolA Brucella suis VBI22 tolA protein YP_005155357.1 1643431 R 1112912 CDS YP_005155358.1 376281352 11729304 complement(1644509..1644961) 1 NC_016797.1 identified by match to protein family HMM PF02472; ExbD/TolR family TonB system transport protein 1644961 11729304 BSVBI22_A1695 Brucella suis VBI22 ExbD/TolR family TonB system transport protein YP_005155358.1 1644509 R 1112912 CDS YP_005155359.1 376281353 11729305 complement(1645008..1645718) 1 NC_016797.1 identified by match to protein family HMM PF01618; tolQ protein 1645718 tolQ 11729305 tolQ Brucella suis VBI22 tolQ protein YP_005155359.1 1645008 R 1112912 CDS YP_005155360.1 376281354 11729306 complement(1646093..1646374) 1 NC_016797.1 hypothetical protein 1646374 11729306 BSVBI22_A1697 Brucella suis VBI22 hypothetical protein YP_005155360.1 1646093 R 1112912 CDS YP_005155361.1 376281355 11729307 complement(1646522..1647562) 1 NC_016797.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1647562 ruvB 11729307 ruvB Brucella suis VBI22 Holliday junction DNA helicase RuvB YP_005155361.1 1646522 R 1112912 CDS YP_005155362.1 376281356 11729308 complement(1647603..1648220) 1 NC_016797.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1648220 ruvA 11729308 ruvA Brucella suis VBI22 Holliday junction DNA helicase RuvA YP_005155362.1 1647603 R 1112912 CDS YP_005155363.1 376281357 11729309 complement(1648225..1648746) 1 NC_016797.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1648746 ruvC 11729309 ruvC Brucella suis VBI22 Holliday junction resolvase YP_005155363.1 1648225 R 1112912 CDS YP_005155364.1 376281358 11729310 complement(1648848..1649354) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3016; hypothetical protein 1649354 11729310 BSVBI22_A1701 Brucella suis VBI22 hypothetical protein YP_005155364.1 1648848 R 1112912 CDS YP_005155365.1 376281359 11729311 complement(1649841..1651022) 1 NC_016797.1 identified by similarity to GP:9961345; opgC protein 1651022 11729311 BSVBI22_A1702 Brucella suis VBI22 opgC protein YP_005155365.1 1649841 R 1112912 CDS YP_005155366.1 376281360 11729312 1651267..1651932 1 NC_016797.1 catalyzes the formation of thiamine monophosphate from 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate and 4-methyl-5-(2-phosphono-oxyethyl)-thiazole; thiamine-phosphate pyrophosphorylase 1651932 11729312 BSVBI22_A1703 Brucella suis VBI22 thiamine-phosphate pyrophosphorylase YP_005155366.1 1651267 D 1112912 CDS YP_005155367.1 376281361 11729313 1651933..1653021 1 NC_016797.1 identified by similarity to GP:14024100; hypothetical protein 1653021 11729313 BSVBI22_A1704 Brucella suis VBI22 hypothetical protein YP_005155367.1 1651933 D 1112912 CDS YP_005155368.1 376281362 11729314 1653030..1653137 1 NC_016797.1 hypothetical protein 1653137 11729314 BSVBI22_A1705 Brucella suis VBI22 hypothetical protein YP_005155368.1 1653030 D 1112912 CDS YP_005155369.1 376281363 11729315 1653286..1653846 1 NC_016797.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1653846 efp 11729315 efp Brucella suis VBI22 elongation factor P YP_005155369.1 1653286 D 1112912 CDS YP_005155370.1 376281364 11729316 1654032..1654823 1 NC_016797.1 identified by similarity to EGAD:15335; match to protein family HMM PF00459; inositol monophosphatase family protein 1654823 11729316 BSVBI22_A1707 Brucella suis VBI22 inositol monophosphatase family protein YP_005155370.1 1654032 D 1112912 CDS YP_005155371.1 376281365 11729317 1654828..1654938 1 NC_016797.1 hypothetical protein 1654938 11729317 BSVBI22_A1708 Brucella suis VBI22 hypothetical protein YP_005155371.1 1654828 D 1112912 CDS YP_005155372.1 376281366 11729318 1655078..1656127 1 NC_016797.1 identified by similarity to GP:15075801; hypothetical protein 1656127 11729318 BSVBI22_A1709 Brucella suis VBI22 hypothetical protein YP_005155372.1 1655078 D 1112912 CDS YP_005155373.1 376281367 11729319 1656134..1657165 1 NC_016797.1 identified by match to protein family HMM PF00691; hypothetical protein 1657165 11729319 BSVBI22_A1710 Brucella suis VBI22 hypothetical protein YP_005155373.1 1656134 D 1112912 CDS YP_005155374.1 376281368 11729320 complement(1657199..1658998) 1 NC_016797.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 1658998 11729320 BSVBI22_A1711 Brucella suis VBI22 ABC transporter ATP-binding protein/permease YP_005155374.1 1657199 R 1112912 CDS YP_005155375.1 376281369 11729321 1659314..1659535 1 NC_016797.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1659535 rpmE 11729321 rpmE Brucella suis VBI22 50S ribosomal protein L31 YP_005155375.1 1659314 D 1112912 CDS YP_005155376.1 376281370 11729322 complement(1659763..1660509) 1 NC_016797.1 identified by similarity to GP:15075777; match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 1660509 11729322 BSVBI22_A1713 Brucella suis VBI22 hypothetical protein YP_005155376.1 1659763 R 1112912 CDS YP_005155377.1 376281371 11729324 1661585..1662160 1 NC_016797.1 identified by match to protein family HMM PF02632; BioY family protein 1662160 11729324 BSVBI22_A1715 Brucella suis VBI22 BioY family protein YP_005155377.1 1661585 D 1112912 CDS YP_005155378.1 376281372 11729325 1662171..1662599 1 NC_016797.1 identified by similarity to GP:14026938; hypothetical protein 1662599 11729325 BSVBI22_A1716 Brucella suis VBI22 hypothetical protein YP_005155378.1 1662171 D 1112912 CDS YP_005155379.1 376281373 11729326 complement(1662612..1663355) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3047; match to protein family HMM PF03741; hypothetical protein 1663355 11729326 BSVBI22_A1717 Brucella suis VBI22 hypothetical protein YP_005155379.1 1662612 R 1112912 CDS YP_005155380.1 376281374 11729327 complement(1663566..1664390) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3048; match to protein family HMM PF00149; match to protein family HMM TIGR00282; hypothetical protein 1664390 11729327 BSVBI22_A1718 Brucella suis VBI22 hypothetical protein YP_005155380.1 1663566 R 1112912 CDS YP_005155381.1 376281375 11729328 complement(1664499..1665095) 1 NC_016797.1 identified by match to protein family HMM PF01812; 5-formyltetrahydrofolate cyclo-ligase 1665095 11729328 BSVBI22_A1719 Brucella suis VBI22 5-formyltetrahydrofolate cyclo-ligase YP_005155381.1 1664499 R 1112912 CDS YP_005155382.1 376281376 11729329 complement(1665483..1665848) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2891; match to protein family HMM PF05164; hypothetical protein 1665848 11729329 BSVBI22_A1720 Brucella suis VBI22 hypothetical protein YP_005155382.1 1665483 R 1112912 CDS YP_005155383.1 376281377 11729330 complement(1665858..1666130) 1 NC_016797.1 hypothetical protein 1666130 11729330 BSVBI22_A1721 Brucella suis VBI22 hypothetical protein YP_005155383.1 1665858 R 1112912 CDS YP_005155384.1 376281378 11729331 complement(1666273..1666368) 1 NC_016797.1 hypothetical protein 1666368 11729331 BSVBI22_A1722 Brucella suis VBI22 hypothetical protein YP_005155384.1 1666273 R 1112912 CDS YP_005155385.1 376281379 11729332 1666547..1668538 1 NC_016797.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1668538 tkt 11729332 tkt Brucella suis VBI22 transketolase YP_005155385.1 1666547 D 1112912 CDS YP_005155386.1 376281380 11729333 1668679..1669686 1 NC_016797.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1669686 gap 11729333 gap Brucella suis VBI22 glyceraldehyde-3-phosphate dehydrogenase YP_005155386.1 1668679 D 1112912 CDS YP_005155387.1 376281381 11729334 1669757..1670944 1 NC_016797.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1670944 pgk 11729334 pgk Brucella suis VBI22 phosphoglycerate kinase YP_005155387.1 1669757 D 1112912 CDS YP_005155388.1 376281382 11729335 complement(1671235..1671399) 1 NC_016797.1 identified by similarity to GP:15075794; hypothetical protein 1671399 11729335 BSVBI22_A1726 Brucella suis VBI22 hypothetical protein YP_005155388.1 1671235 R 1112912 CDS YP_005155389.1 376281383 11729336 1671673..1673583 1 NC_016797.1 identified by match to protein family HMM PF00501; propionate--CoA ligase 1673583 prpE 11729336 prpE Brucella suis VBI22 propionate--CoA ligase YP_005155389.1 1671673 D 1112912 CDS YP_005155390.1 376281384 11729337 1673513..1673821 1 NC_016797.1 identified by similarity to GP:7206791; hypothetical protein 1673821 11729337 BSVBI22_A1728 Brucella suis VBI22 hypothetical protein YP_005155390.1 1673513 D 1112912 CDS YP_005155391.1 376281385 11729338 1673928..1674152 1 NC_016797.1 hypothetical protein 1674152 11729338 BSVBI22_A1729 Brucella suis VBI22 hypothetical protein YP_005155391.1 1673928 D 1112912 CDS YP_005155392.1 376281386 11729339 1674159..1674860 1 NC_016797.1 transcriptional regulator 1674860 11729339 BSVBI22_A1730 Brucella suis VBI22 transcriptional regulator YP_005155392.1 1674159 D 1112912 CDS YP_005155393.1 376281387 11729340 complement(1675113..1675220) 1 NC_016797.1 hypothetical protein 1675220 11729340 BSVBI22_A1731 Brucella suis VBI22 hypothetical protein YP_005155393.1 1675113 R 1112912 CDS YP_005155394.1 376281388 11729341 1675263..1675670 1 NC_016797.1 identified by similarity to OMNI:CC2103; match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 1675670 11729341 BSVBI22_A1732 Brucella suis VBI22 hypothetical protein YP_005155394.1 1675263 D 1112912 CDS YP_005155395.1 376281389 11729342 complement(1675748..1676437) 1 NC_016797.1 identified by similarity to GP:15076354; hypothetical protein 1676437 11729342 BSVBI22_A1733 Brucella suis VBI22 hypothetical protein YP_005155395.1 1675748 R 1112912 CDS YP_005155396.1 376281390 11729343 complement(1676565..1677545) 1 NC_016797.1 identified by match to protein family HMM PF00107; zinc-containing alcohol dehydrogenase 1677545 11729343 BSVBI22_A1734 Brucella suis VBI22 zinc-containing alcohol dehydrogenase YP_005155396.1 1676565 R 1112912 CDS YP_005155397.1 376281391 11729344 1677762..1677953 1 NC_016797.1 identified by similarity to GP:15075796; hypothetical protein 1677953 11729344 BSVBI22_A1735 Brucella suis VBI22 hypothetical protein YP_005155397.1 1677762 D 1112912 CDS YP_005155398.1 376281392 11729345 1678051..1679289 1 NC_016797.1 transporter 1679289 11729345 BSVBI22_A1736 Brucella suis VBI22 transporter YP_005155398.1 1678051 D 1112912 CDS YP_005155399.1 376281393 11729346 complement(1679432..1679611) 1 NC_016797.1 identified by match to protein family HMM PF04325; hypothetical protein 1679611 11729346 BSVBI22_A1737 Brucella suis VBI22 hypothetical protein YP_005155399.1 1679432 R 1112912 CDS YP_005155400.1 376281394 11729347 complement(1679670..1679891) 1 NC_016797.1 hypothetical protein 1679891 11729347 BSVBI22_A1738 Brucella suis VBI22 hypothetical protein YP_005155400.1 1679670 R 1112912 CDS YP_005155401.1 376281395 11729348 1680005..1680208 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2929; match to protein family HMM PF04325; hypothetical protein 1680208 11729348 BSVBI22_A1739 Brucella suis VBI22 hypothetical protein YP_005155401.1 1680005 D 1112912 CDS YP_005155402.1 376281396 11729349 1680306..1680794 1 NC_016797.1 identified by similarity to SP:P09028; match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase catalytic subunit 1680794 purE 11729349 purE Brucella suis VBI22 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_005155402.1 1680306 D 1112912 CDS YP_005155403.1 376281397 11729350 1680886..1681899 1 NC_016797.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1681899 purK 11729350 purK Brucella suis VBI22 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_005155403.1 1680886 D 1112912 CDS YP_005155404.1 376281398 11729351 1682135..1682260 1 NC_016797.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 1682260 rpmJ 11729351 rpmJ Brucella suis VBI22 50S ribosomal protein L36 YP_005155404.1 1682135 D 1112912 CDS YP_005155405.1 376281399 11729352 1682298..1682987 1 NC_016797.1 identified by match to protein family HMM PF00515; hypothetical protein 1682987 11729352 BSVBI22_A1743 Brucella suis VBI22 hypothetical protein YP_005155405.1 1682298 D 1112912 CDS YP_005155406.1 376281400 11729353 complement(1683239..1684675) 1 NC_016797.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1684675 pyk 11729353 pyk Brucella suis VBI22 pyruvate kinase YP_005155406.1 1683239 R 1112912 CDS YP_005155407.1 376281401 11729354 complement(1684672..1685133) 1 NC_016797.1 hypothetical protein 1685133 11729354 BSVBI22_A1745 Brucella suis VBI22 hypothetical protein YP_005155407.1 1684672 R 1112912 CDS YP_005155408.1 376281402 11729355 1685374..1686192 1 NC_016797.1 identified by match to protein family HMM PF05013; hypothetical protein 1686192 11729355 BSVBI22_A1746 Brucella suis VBI22 hypothetical protein YP_005155408.1 1685374 D 1112912 CDS YP_005155409.1 376281403 11729356 1686189..1686350 1 NC_016797.1 hypothetical protein 1686350 11729356 BSVBI22_A1747 Brucella suis VBI22 hypothetical protein YP_005155409.1 1686189 D 1112912 CDS YP_005155410.1 376281404 11729357 1686365..1686625 1 NC_016797.1 hypothetical protein 1686625 11729357 BSVBI22_A1748 Brucella suis VBI22 hypothetical protein YP_005155410.1 1686365 D 1112912 CDS YP_005155411.1 376281405 11729358 complement(1686717..1688534) 1 NC_016797.1 identified by similarity to GP:15157929; match to protein family HMM PF00005; ABC transporter ATP-binding protein 1688534 11729358 BSVBI22_A1749 Brucella suis VBI22 ABC transporter ATP-binding protein YP_005155411.1 1686717 R 1112912 CDS YP_005155412.1 376281406 11729359 complement(1688543..1688713) 1 NC_016797.1 hypothetical protein 1688713 11729359 BSVBI22_A1750 Brucella suis VBI22 hypothetical protein YP_005155412.1 1688543 R 1112912 CDS YP_005155413.1 376281407 11729360 complement(1688682..1688966) 1 NC_016797.1 putative lipoprotein 1688966 11729360 BSVBI22_A1751 Brucella suis VBI22 putative lipoprotein YP_005155413.1 1688682 R 1112912 CDS YP_005155414.1 376281408 11729361 complement(1689100..1689756) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2986; match to protein family HMM PF04263; hypothetical protein 1689756 11729361 BSVBI22_A1752 Brucella suis VBI22 hypothetical protein YP_005155414.1 1689100 R 1112912 CDS YP_005155415.1 376281409 11729362 1690063..1691067 1 NC_016797.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 1691067 tbpA 11729362 tbpA Brucella suis VBI22 thiamine transporter substrate binding subunit YP_005155415.1 1690063 D 1112912 CDS YP_005155416.1 376281410 11729363 1691064..1692695 1 NC_016797.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 1692695 thiP 11729363 thiP Brucella suis VBI22 thiamine transporter membrane protein YP_005155416.1 1691064 D 1112912 CDS YP_005155417.1 376281411 11729364 1692692..1693417 1 NC_016797.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01277; thiamine ABC transporter ATP-binding protein 1693417 11729364 BSVBI22_A1755 Brucella suis VBI22 thiamine ABC transporter ATP-binding protein YP_005155417.1 1692692 D 1112912 CDS YP_005155418.1 376281412 11729365 complement(1693414..1693509) 1 NC_016797.1 hypothetical protein 1693509 11729365 BSVBI22_A1756 Brucella suis VBI22 hypothetical protein YP_005155418.1 1693414 R 1112912 CDS YP_005155419.1 376281413 11729366 1693684..1695165 1 NC_016797.1 identified by match to protein family HMM PF01435; peptidase 1695165 11729366 BSVBI22_A1757 Brucella suis VBI22 peptidase YP_005155419.1 1693684 D 1112912 CDS YP_005155420.1 376281414 11729367 1695192..1695920 1 NC_016797.1 identified by similarity to OMNI:NTL03PA02229; match to protein family HMM PF03473; MOSC domain-containing protein 1695920 11729367 BSVBI22_A1758 Brucella suis VBI22 MOSC domain-containing protein YP_005155420.1 1695192 D 1112912 CDS YP_005155421.1 376281415 11729368 complement(1696008..1696943) 1 NC_016797.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production; RNA polymerase factor sigma-32 1696943 rpoH2 11729368 rpoH2 Brucella suis VBI22 RNA polymerase factor sigma-32 YP_005155421.1 1696008 R 1112912 CDS YP_005155422.1 376281416 11729369 1696984..1697187 1 NC_016797.1 hypothetical protein 1697187 11729369 BSVBI22_A1760 Brucella suis VBI22 hypothetical protein YP_005155422.1 1696984 D 1112912 CDS YP_005155423.1 376281417 11729370 complement(1697107..1697316) 1 NC_016797.1 hypothetical protein 1697316 11729370 BSVBI22_A1761 Brucella suis VBI22 hypothetical protein YP_005155423.1 1697107 R 1112912 CDS YP_005155424.1 376281418 11729371 complement(1697288..1697863) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2976; match to protein family HMM PF02559; transcriptional regulator 1697863 11729371 BSVBI22_A1762 Brucella suis VBI22 transcriptional regulator YP_005155424.1 1697288 R 1112912 CDS YP_005155425.1 376281419 11729372 complement(1698381..1698719) 1 NC_016797.1 identified by similarity to EGAD:22805; match to protein family HMM PF00037; ferredoxin A 1698719 fdxA 11729372 fdxA Brucella suis VBI22 ferredoxin A YP_005155425.1 1698381 R 1112912 CDS YP_005155426.1 376281420 11729373 complement(1698852..1699085) 1 NC_016797.1 hypothetical protein 1699085 11729373 BSVBI22_A1764 Brucella suis VBI22 hypothetical protein YP_005155426.1 1698852 R 1112912 CDS YP_005155427.1 376281421 11729374 complement(1699082..1699495) 1 NC_016797.1 identified by match to protein family HMM PF01479; S4 domain-containing protein 1699495 11729374 BSVBI22_A1765 Brucella suis VBI22 S4 domain-containing protein YP_005155427.1 1699082 R 1112912 CDS YP_005155428.1 376281422 11729376 complement(1702975..1703295) 1 NC_016797.1 hypothetical protein 1703295 11729376 BSVBI22_A1767 Brucella suis VBI22 hypothetical protein YP_005155428.1 1702975 R 1112912 CDS YP_005155429.1 376281423 11729377 complement(1703279..1704463) 1 NC_016797.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 1704463 phbA-1 11729377 phbA-1 Brucella suis VBI22 acetyl-CoA acetyltransferase YP_005155429.1 1703279 R 1112912 CDS YP_005155430.1 376281424 11729378 1704444..1704608 1 NC_016797.1 hypothetical protein 1704608 11729378 BSVBI22_A1769 Brucella suis VBI22 hypothetical protein YP_005155430.1 1704444 D 1112912 CDS YP_005155431.1 376281425 11729379 1704639..1705070 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2916; match to protein family HMM PF03928; hypothetical protein 1705070 11729379 BSVBI22_A1770 Brucella suis VBI22 hypothetical protein YP_005155431.1 1704639 D 1112912 CDS YP_005155432.1 376281426 11729380 complement(1705202..1705381) 1 NC_016797.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1705381 rpmF 11729380 rpmF Brucella suis VBI22 50S ribosomal protein L32 YP_005155432.1 1705202 R 1112912 CDS YP_005155433.1 376281427 11729381 complement(1705542..1706276) 1 NC_016797.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 1706276 mtgA 11729381 mtgA Brucella suis VBI22 monofunctional biosynthetic peptidoglycan transglycosylase YP_005155433.1 1705542 R 1112912 CDS YP_005155434.1 376281428 11729382 1706463..1707377 1 NC_016797.1 identified by similarity to SP:Q08291; match to protein family HMM PF00348; geranyltranstransferase 1707377 ispA 11729382 ispA Brucella suis VBI22 geranyltranstransferase YP_005155434.1 1706463 D 1112912 CDS YP_005155435.1 376281429 11729383 complement(1707385..1708647) 1 NC_016797.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1708647 ispG 11729383 ispG Brucella suis VBI22 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_005155435.1 1707385 R 1112912 CDS YP_005155436.1 376281430 11729384 1708815..1709606 1 NC_016797.1 identified by similarity to SP:O86034; match to protein family HMM PF00106; match to protein family HMM TIGR01963; D-beta-hydroxybutyrate dehydrogenase 1709606 11729384 BSVBI22_A1775 Brucella suis VBI22 D-beta-hydroxybutyrate dehydrogenase YP_005155436.1 1708815 D 1112912 CDS YP_005155437.1 376281431 11729386 complement(1710880..1714356) 1 NC_016797.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 1714356 pyc 11729386 pyc Brucella suis VBI22 pyruvate carboxylase YP_005155437.1 1710880 R 1112912 CDS YP_005155438.1 376281432 11729387 complement(1714622..1715737) 1 NC_016797.1 identified by similarity to SP:P04816; match to protein family HMM PF01094; branched-chain amino acid ABC transporter substrate-binding protein 1715737 11729387 BSVBI22_A1778 Brucella suis VBI22 branched-chain amino acid ABC transporter substrate-binding protein YP_005155438.1 1714622 R 1112912 CDS YP_005155439.1 376281433 11729388 complement(1715880..1716011) 1 NC_016797.1 hypothetical protein 1716011 11729388 BSVBI22_A1779 Brucella suis VBI22 hypothetical protein YP_005155439.1 1715880 R 1112912 CDS YP_005155440.1 376281434 11729389 1716015..1716167 1 NC_016797.1 hypothetical protein 1716167 11729389 BSVBI22_A1780 Brucella suis VBI22 hypothetical protein YP_005155440.1 1716015 D 1112912 CDS YP_005155441.1 376281435 11729390 complement(1716358..1717473) 1 NC_016797.1 identified by similarity to SP:P04816; match to protein family HMM PF01094; branched-chain amino acid ABC transporter substrate-binding protein 1717473 11729390 BSVBI22_A1781 Brucella suis VBI22 branched-chain amino acid ABC transporter substrate-binding protein YP_005155441.1 1716358 R 1112912 CDS YP_005155442.1 376281436 11729391 1717492..1717623 1 NC_016797.1 hypothetical protein 1717623 11729391 BSVBI22_A1782 Brucella suis VBI22 hypothetical protein YP_005155442.1 1717492 D 1112912 CDS YP_005155443.1 376281437 11729392 complement(1717625..1717969) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3062; hypothetical protein 1717969 11729392 BSVBI22_A1783 Brucella suis VBI22 hypothetical protein YP_005155443.1 1717625 R 1112912 CDS YP_005155444.1 376281438 11729394 complement(1718723..1720045) 1 NC_016797.1 identified by match to protein family HMM PF00005; branched-chain amino acid ABC transporter ATP-binding protein 1720045 11729394 BSVBI22_A1785 Brucella suis VBI22 branched-chain amino acid ABC transporter ATP-binding protein YP_005155444.1 1718723 R 1112912 CDS YP_005155445.1 376281439 11729395 complement(1720063..1721442) 1 NC_016797.1 identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 1721442 11729395 BSVBI22_A1786 Brucella suis VBI22 branched-chain amino acid ABC transporter permease YP_005155445.1 1720063 R 1112912 CDS YP_005155446.1 376281440 11729396 complement(1721445..1722353) 1 NC_016797.1 identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 1722353 11729396 BSVBI22_A1787 Brucella suis VBI22 branched-chain amino acid ABC transporter permease YP_005155446.1 1721445 R 1112912 CDS YP_005155447.1 376281441 11729397 complement(1722647..1723648) 1 NC_016797.1 identified by similarity to GP:9695312; match to protein family HMM PF05544; hydroxyproline-2-epimerase 1723648 11729397 BSVBI22_A1788 Brucella suis VBI22 hydroxyproline-2-epimerase YP_005155447.1 1722647 R 1112912 CDS YP_005155448.1 376281442 11729399 1724939..1725139 1 NC_016797.1 hypothetical protein 1725139 11729399 BSVBI22_A1790 Brucella suis VBI22 hypothetical protein YP_005155448.1 1724939 D 1112912 CDS YP_005155449.1 376281443 11729400 1725195..1725890 1 NC_016797.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1725890 11729400 BSVBI22_A1791 Brucella suis VBI22 GntR family transcriptional regulator YP_005155449.1 1725195 D 1112912 CDS YP_005155450.1 376281444 11729401 complement(1725963..1726538) 1 NC_016797.1 identified by similarity to EGAD:16739; match to protein family HMM PF01047; MarR family transcriptional regulator 1726538 11729401 BSVBI22_A1792 Brucella suis VBI22 MarR family transcriptional regulator YP_005155450.1 1725963 R 1112912 CDS YP_005155451.1 376281445 11729402 complement(1726561..1726662) 1 NC_016797.1 hypothetical protein 1726662 11729402 BSVBI22_A1793 Brucella suis VBI22 hypothetical protein YP_005155451.1 1726561 R 1112912 CDS YP_005155452.1 376281446 11729403 complement(1726743..1727150) 1 NC_016797.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1727150 atpC 11729403 atpC Brucella suis VBI22 F0F1 ATP synthase subunit epsilon YP_005155452.1 1726743 R 1112912 CDS YP_005155453.1 376281447 11729404 complement(1727275..1728840) 1 NC_016797.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1728840 atpD 11729404 atpD Brucella suis VBI22 F0F1 ATP synthase subunit beta YP_005155453.1 1727275 R 1112912 CDS YP_005155454.1 376281448 11729405 complement(1728968..1729846) 1 NC_016797.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1729846 atpG 11729405 atpG Brucella suis VBI22 F0F1 ATP synthase subunit gamma YP_005155454.1 1728968 R 1112912 CDS YP_005155455.1 376281449 11729406 complement(1729868..1731397) 1 NC_016797.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1731397 atpA 11729406 atpA Brucella suis VBI22 F0F1 ATP synthase subunit alpha YP_005155455.1 1729868 R 1112912 CDS YP_005155456.1 376281450 11729407 complement(1731397..1731957) 1 NC_016797.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1731957 atpH 11729407 atpH Brucella suis VBI22 F0F1 ATP synthase subunit delta YP_005155456.1 1731397 R 1112912 CDS YP_005155457.1 376281451 11729408 complement(1732239..1732652) 1 NC_016797.1 identified by similarity to GP:15076063; hypothetical protein 1732652 11729408 BSVBI22_A1799 Brucella suis VBI22 hypothetical protein YP_005155457.1 1732239 R 1112912 CDS YP_005155458.1 376281452 11729409 complement(1732719..1734953) 1 NC_016797.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1734953 priA 11729409 priA Brucella suis VBI22 primosome assembly protein PriA YP_005155458.1 1732719 R 1112912 CDS YP_005155459.1 376281453 11729410 1735063..1735716 1 NC_016797.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; putative translaldolase 1735716 11729410 BSVBI22_A1801 Brucella suis VBI22 putative translaldolase YP_005155459.1 1735063 D 1112912 CDS YP_005155460.1 376281454 11729411 complement(1735860..1736441) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3139; hypothetical protein 1736441 11729411 BSVBI22_A1802 Brucella suis VBI22 hypothetical protein YP_005155460.1 1735860 R 1112912 CDS YP_005155461.1 376281455 11729412 complement(1736428..1739061) 1 NC_016797.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1739061 leuS 11729412 leuS Brucella suis VBI22 leucyl-tRNA synthetase YP_005155461.1 1736428 R 1112912 CDS YP_005155462.1 376281456 11729413 1739184..1739864 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3141; match to protein family HMM PF01168; match to protein family HMM TIGR00044; hypothetical protein 1739864 11729413 BSVBI22_A1804 Brucella suis VBI22 hypothetical protein YP_005155462.1 1739184 D 1112912 CDS YP_005155463.1 376281457 11729414 complement(1739877..1740407) 1 NC_016797.1 hypothetical protein 1740407 11729414 BSVBI22_A1805 Brucella suis VBI22 hypothetical protein YP_005155463.1 1739877 R 1112912 CDS YP_005155464.1 376281458 11729415 complement(1740478..1740765) 1 NC_016797.1 identified by similarity to EGAD:13628; usg protein 1740765 11729415 BSVBI22_A1806 Brucella suis VBI22 usg protein YP_005155464.1 1740478 R 1112912 CDS YP_005155465.1 376281459 11729416 1741106..1743061 1 NC_016797.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 1743061 11729416 BSVBI22_A1807 Brucella suis VBI22 acetyl-CoA synthetase YP_005155465.1 1741106 D 1112912 CDS YP_005155466.1 376281460 11729417 complement(1743217..1743444) 1 NC_016797.1 identified by similarity to GP:14024231; hypothetical protein 1743444 11729417 BSVBI22_A1808 Brucella suis VBI22 hypothetical protein YP_005155466.1 1743217 R 1112912 CDS YP_005155467.1 376281461 11729418 1743567..1744544 1 NC_016797.1 putative metalloprotease; heat shock protein HtpX 1744544 htpX 11729418 htpX Brucella suis VBI22 heat shock protein HtpX YP_005155467.1 1743567 D 1112912 CDS YP_005155468.1 376281462 11729419 1744560..1745957 1 NC_016797.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; sun protein 1745957 sun 11729419 sun Brucella suis VBI22 sun protein YP_005155468.1 1744560 D 1112912 CDS YP_005155469.1 376281463 11729420 1746189..1747820 1 NC_016797.1 identified by similarity to GP:14024235; hypothetical protein 1747820 11729420 BSVBI22_A1811 Brucella suis VBI22 hypothetical protein YP_005155469.1 1746189 D 1112912 CDS YP_005155470.1 376281464 11729421 1747927..1749543 1 NC_016797.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1749543 purH 11729421 purH Brucella suis VBI22 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_005155470.1 1747927 D 1112912 CDS YP_005155471.1 376281465 11729422 complement(1749593..1750960) 1 NC_016797.1 hypothetical protein 1750960 11729422 BSVBI22_A1813 Brucella suis VBI22 hypothetical protein YP_005155471.1 1749593 R 1112912 CDS YP_005155472.1 376281466 11729423 1750894..1751202 1 NC_016797.1 hypothetical protein 1751202 11729423 BSVBI22_A1814 Brucella suis VBI22 hypothetical protein YP_005155472.1 1750894 D 1112912 CDS YP_005155473.1 376281467 11729424 complement(1751180..1755982) 1 NC_016797.1 identified by similarity to GP:15076346; match to protein family HMM PF05088; match to protein family HMM TIGR01612; hypothetical protein 1755982 11729424 BSVBI22_A1815 Brucella suis VBI22 hypothetical protein YP_005155473.1 1751180 R 1112912 CDS YP_005155474.1 376281468 11729425 complement(1756247..1756888) 1 NC_016797.1 identified by similarity to GP:14024253; hypothetical protein 1756888 11729425 BSVBI22_A1816 Brucella suis VBI22 hypothetical protein YP_005155474.1 1756247 R 1112912 CDS YP_005155475.1 376281469 11729426 complement(1756901..1757704) 1 NC_016797.1 identified by similarity to GP:14024255; match to protein family HMM PF04536; hypothetical protein 1757704 11729426 BSVBI22_A1817 Brucella suis VBI22 hypothetical protein YP_005155475.1 1756901 R 1112912 CDS YP_005155476.1 376281470 11729427 complement(1757785..1758408) 1 NC_016797.1 identified by similarity to EGAD:149857; match to protein family HMM PF04011; hypothetical protein 1758408 11729427 BSVBI22_A1818 Brucella suis VBI22 hypothetical protein YP_005155476.1 1757785 R 1112912 CDS YP_005155477.1 376281471 11729428 complement(1758405..1758578) 1 NC_016797.1 hypothetical protein 1758578 11729428 BSVBI22_A1819 Brucella suis VBI22 hypothetical protein YP_005155477.1 1758405 R 1112912 CDS YP_005155478.1 376281472 11729429 complement(1758678..1759082) 1 NC_016797.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1759082 rpsP 11729429 rpsP Brucella suis VBI22 30S ribosomal protein S16 YP_005155478.1 1758678 R 1112912 CDS YP_005155479.1 376281473 11729430 complement(1759149..1759463) 1 NC_016797.1 catalyzes the interconversion of chorismate to prephenate; chorismate mutase 1759463 11729430 BSVBI22_A1821 Brucella suis VBI22 chorismate mutase YP_005155479.1 1759149 R 1112912 CDS YP_005155480.1 376281474 11729431 complement(1759469..1761040) 1 NC_016797.1 identified by similarity to EGAD:6526; match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein 1761040 ffh 11729431 ffh Brucella suis VBI22 signal recognition particle protein YP_005155480.1 1759469 R 1112912 CDS YP_005155481.1 376281475 11729432 1761164..1761535 1 NC_016797.1 hypothetical protein 1761535 11729432 BSVBI22_A1823 Brucella suis VBI22 hypothetical protein YP_005155481.1 1761164 D 1112912 CDS YP_005155482.1 376281476 11729433 1761475..1762302 1 NC_016797.1 identified by similarity to OMNI:VC1956; lytic murein transglycosylase 1762302 11729433 BSVBI22_A1824 Brucella suis VBI22 lytic murein transglycosylase YP_005155482.1 1761475 D 1112912 CDS YP_005155483.1 376281477 11729434 complement(1762366..1763007) 1 NC_016797.1 identified by match to protein family HMM PF00484; carbonic anhydrase 1763007 11729434 BSVBI22_A1825 Brucella suis VBI22 carbonic anhydrase YP_005155483.1 1762366 R 1112912 CDS YP_005155484.1 376281478 11729435 complement(1763181..1764077) 1 NC_016797.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1764077 11729435 BSVBI22_A1826 Brucella suis VBI22 pyridoxamine kinase YP_005155484.1 1763181 R 1112912 CDS YP_005155485.1 376281479 11729436 complement(1764079..1764366) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3181; hypothetical protein 1764366 11729436 BSVBI22_A1827 Brucella suis VBI22 hypothetical protein YP_005155485.1 1764079 R 1112912 CDS YP_005155486.1 376281480 11729437 complement(1764739..1766235) 1 NC_016797.1 identified by similarity to SP:P28810; match to protein family HMM PF00171; match to protein family HMM TIGR01722; methylmalonic acid semialdehyde dehydrogenase 1766235 mmsA 11729437 mmsA Brucella suis VBI22 methylmalonic acid semialdehyde dehydrogenase YP_005155486.1 1764739 R 1112912 CDS YP_005155487.1 376281481 11729438 1766363..1767268 1 NC_016797.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1767268 11729438 BSVBI22_A1829 Brucella suis VBI22 LysR family transcriptional regulator YP_005155487.1 1766363 D 1112912 CDS YP_005155488.1 376281482 11729439 complement(1767479..1768087) 1 NC_016797.1 hypothetical protein 1768087 11729439 BSVBI22_A1830 Brucella suis VBI22 hypothetical protein YP_005155488.1 1767479 R 1112912 CDS YP_005155489.1 376281483 11729440 1768081..1768473 1 NC_016797.1 hypothetical protein 1768473 11729440 BSVBI22_A1831 Brucella suis VBI22 hypothetical protein YP_005155489.1 1768081 D 1112912 CDS YP_005155490.1 376281484 11729441 complement(1768525..1769073) 1 NC_016797.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1769073 11729441 BSVBI22_A1832 Brucella suis VBI22 dinucleoside polyphosphate hydrolase YP_005155490.1 1768525 R 1112912 CDS YP_005155491.1 376281485 11729442 complement(1769279..1770553) 1 NC_016797.1 identified by match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; carboxyl-terminal protease 1770553 11729442 BSVBI22_A1833 Brucella suis VBI22 carboxyl-terminal protease YP_005155491.1 1769279 R 1112912 CDS YP_005155492.1 376281486 11729443 complement(1770597..1771946) 1 NC_016797.1 hypothetical protein 1771946 11729443 BSVBI22_A1834 Brucella suis VBI22 hypothetical protein YP_005155492.1 1770597 R 1112912 CDS YP_005155493.1 376281487 11729444 complement(1772059..1772958) 1 NC_016797.1 hypothetical protein 1772958 11729444 BSVBI22_A1835 Brucella suis VBI22 hypothetical protein YP_005155493.1 1772059 R 1112912 CDS YP_005155494.1 376281488 11729445 complement(1773076..1773600) 1 NC_016797.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 1773600 11729445 BSVBI22_A1836 Brucella suis VBI22 rRNA large subunit methyltransferase YP_005155494.1 1773076 R 1112912 CDS YP_005155495.1 376281489 11729446 complement(1773619..1773972) 1 NC_016797.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; iojap-like protein 1773972 11729446 BSVBI22_A1837 Brucella suis VBI22 iojap-like protein YP_005155495.1 1773619 R 1112912 CDS YP_005155496.1 376281490 11729447 complement(1774153..1774737) 1 NC_016797.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1774737 nadD 11729447 nadD Brucella suis VBI22 nicotinic acid mononucleotide adenylyltransferase YP_005155496.1 1774153 R 1112912 CDS YP_005155497.1 376281491 11729448 complement(1774827..1776092) 1 NC_016797.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1776092 proA 11729448 proA Brucella suis VBI22 gamma-glutamyl phosphate reductase YP_005155497.1 1774827 R 1112912 CDS YP_005155498.1 376281492 11729449 complement(1776120..1777256) 1 NC_016797.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1777256 proB 11729449 proB Brucella suis VBI22 gamma-glutamyl kinase YP_005155498.1 1776120 R 1112912 CDS YP_005155499.1 376281493 11729450 complement(1777284..1778309) 1 NC_016797.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1778309 obgE 11729450 obgE Brucella suis VBI22 GTPase ObgE YP_005155499.1 1777284 R 1112912 CDS YP_005155500.1 376281494 11729451 complement(1778565..1779401) 1 NC_016797.1 hypothetical protein 1779401 11729451 BSVBI22_A1842 Brucella suis VBI22 hypothetical protein YP_005155500.1 1778565 R 1112912 CDS YP_005155501.1 376281495 11729452 complement(1779810..1780367) 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 1780367 11729452 BSVBI22_A1843 Brucella suis VBI22 acetyltransferase YP_005155501.1 1779810 R 1112912 CDS YP_005155502.1 376281496 11729453 complement(1780421..1781071) 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 1781071 11729453 BSVBI22_A1844 Brucella suis VBI22 acetyltransferase YP_005155502.1 1780421 R 1112912 CDS YP_005155503.1 376281497 11729454 complement(1781192..1781461) 1 NC_016797.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1781461 rpmA 11729454 rpmA Brucella suis VBI22 50S ribosomal protein L27 YP_005155503.1 1781192 R 1112912 CDS YP_005155504.1 376281498 11729455 complement(1781487..1781915) 1 NC_016797.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 1781915 rplU 11729455 rplU Brucella suis VBI22 50S ribosomal protein L21 YP_005155504.1 1781487 R 1112912 CDS YP_005155505.1 376281499 11729457 1782637..1783323 1 NC_016797.1 transposase 1783323 11729457 BSVBI22_A1847 Brucella suis VBI22 transposase YP_005155505.1 1782637 D 1112912 CDS YP_005155506.1 376281500 11729458 1783564..1785492 1 NC_016797.1 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 1785492 11729458 BSVBI22_A1848 Brucella suis VBI22 Cro/CI family transcriptional regulator YP_005155506.1 1783564 D 1112912 CDS YP_005155507.1 376281501 11729459 1785489..1786163 1 NC_016797.1 identified by match to protein family HMM PF03591; AzlC family protein 1786163 11729459 BSVBI22_A1849 Brucella suis VBI22 AzlC family protein YP_005155507.1 1785489 D 1112912 CDS YP_005155508.1 376281502 11729460 1786576..1786689 1 NC_016797.1 hypothetical protein 1786689 11729460 BSVBI22_A1850 Brucella suis VBI22 hypothetical protein YP_005155508.1 1786576 D 1112912 CDS YP_005155509.1 376281503 11729461 complement(1786722..1787408) 1 NC_016797.1 transposase 1787408 11729461 BSVBI22_A1851 Brucella suis VBI22 transposase YP_005155509.1 1786722 R 1112912 CDS YP_005155510.1 376281504 11729462 complement(1787519..1788958) 1 NC_016797.1 identified by similarity to OMNI:CC1732; hypothetical protein 1788958 11729462 BSVBI22_A1852 Brucella suis VBI22 hypothetical protein YP_005155510.1 1787519 R 1112912 CDS YP_005155511.1 376281505 11729463 complement(1789134..1789808) 1 NC_016797.1 hypothetical protein 1789808 11729463 BSVBI22_A1853 Brucella suis VBI22 hypothetical protein YP_005155511.1 1789134 R 1112912 CDS YP_005155512.1 376281506 11729464 1790126..1790293 1 NC_016797.1 hypothetical protein 1790293 11729464 BSVBI22_A1854 Brucella suis VBI22 hypothetical protein YP_005155512.1 1790126 D 1112912 CDS YP_005155513.1 376281507 11729468 1790681..1790833 1 NC_016797.1 hypothetical protein 1790833 11729468 BSVBI22_A1855 Brucella suis VBI22 hypothetical protein YP_005155513.1 1790681 D 1112912 CDS YP_005155514.1 376281508 11729470 1793788..1794030 1 NC_016797.1 hypothetical protein 1794030 11729470 BSVBI22_A1856 Brucella suis VBI22 hypothetical protein YP_005155514.1 1793788 D 1112912 CDS YP_005155515.1 376281509 11729474 1796946..1798901 1 NC_016797.1 identified by match to protein family HMM PF01551; M24/M37 family peptidase 1798901 11729474 BSVBI22_A1857 Brucella suis VBI22 M24/M37 family peptidase YP_005155515.1 1796946 D 1112912 CDS YP_005155516.1 376281510 11729476 complement(1798969..1800195) 1 NC_016797.1 identified by similarity to GP:15075231; match to protein family HMM PF03734; hypothetical protein 1800195 11729476 BSVBI22_A1858 Brucella suis VBI22 hypothetical protein YP_005155516.1 1798969 R 1112912 CDS YP_005155517.1 376281511 11729478 1800244..1800369 1 NC_016797.1 hypothetical protein 1800369 11729478 BSVBI22_A1859 Brucella suis VBI22 hypothetical protein YP_005155517.1 1800244 D 1112912 CDS YP_005155518.1 376281512 11729479 complement(1800868..1803492) 1 NC_016797.1 identified by similarity to EGAD:20010; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM TIGR01369; ATP-dependent Clp protease, ATP-binding subunit ClpB 1803492 clpB 11729479 clpB Brucella suis VBI22 ATP-dependent Clp protease, ATP-binding subunit ClpB YP_005155518.1 1800868 R 1112912 CDS YP_005155519.1 376281513 11729481 complement(1803691..1804449) 1 NC_016797.1 identified by similarity to GP:15159086; hypothetical protein 1804449 11729481 BSVBI22_A1861 Brucella suis VBI22 hypothetical protein YP_005155519.1 1803691 R 1112912 CDS YP_005155520.1 376281514 11729482 complement(1804430..1804702) 1 NC_016797.1 hypothetical protein 1804702 11729482 BSVBI22_A1862 Brucella suis VBI22 hypothetical protein YP_005155520.1 1804430 R 1112912 CDS YP_005155521.1 376281515 11729484 1804764..1804910 1 NC_016797.1 hypothetical protein 1804910 11729484 BSVBI22_A1863 Brucella suis VBI22 hypothetical protein YP_005155521.1 1804764 D 1112912 CDS YP_005155522.1 376281516 11729486 complement(1804894..1805745) 1 NC_016797.1 identified by match to protein family HMM TIGR00536; hemK protein 1805745 11729486 BSVBI22_A1864 Brucella suis VBI22 hemK protein YP_005155522.1 1804894 R 1112912 CDS YP_005155523.1 376281517 11729488 complement(1805778..1806857) 1 NC_016797.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1806857 prfA 11729488 prfA Brucella suis VBI22 peptide chain release factor 1 YP_005155523.1 1805778 R 1112912 CDS YP_005155524.1 376281518 11729489 complement(1807054..1809324) 1 NC_016797.1 identified by similarity to EGAD:36619; match to protein family HMM PF00391; match to protein family HMM PF01590; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase 1809324 ptsP 11729489 ptsP Brucella suis VBI22 phosphoenolpyruvate-protein phosphotransferase YP_005155524.1 1807054 R 1112912 CDS YP_005155525.1 376281519 11729490 complement(1809652..1810923) 1 NC_016797.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1810923 11729490 BSVBI22_A1867 Brucella suis VBI22 aspartate kinase YP_005155525.1 1809652 R 1112912 CDS YP_005155526.1 376281520 11729491 1811141..1811887 1 NC_016797.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 1811887 ubiG 11729491 ubiG Brucella suis VBI22 3-demethylubiquinone-9 3-methyltransferase YP_005155526.1 1811141 D 1112912 CDS YP_005155527.1 376281521 11729492 complement(1811893..1812774) 1 NC_016797.1 identified by match to protein family HMM PF00892; hypothetical protein 1812774 11729492 BSVBI22_A1869 Brucella suis VBI22 hypothetical protein YP_005155527.1 1811893 R 1112912 CDS YP_005155528.1 376281522 11729493 complement(1812814..1813272) 1 NC_016797.1 identified by similarity to GP:15159831; hypothetical protein 1813272 11729493 BSVBI22_A1870 Brucella suis VBI22 hypothetical protein YP_005155528.1 1812814 R 1112912 CDS YP_005155529.1 376281523 11729494 complement(1813245..1814099) 1 NC_016797.1 identified by match to protein family HMM PF00795; carbon-nitrogen hydrolase family protein 1814099 11729494 BSVBI22_A1871 Brucella suis VBI22 carbon-nitrogen hydrolase family protein YP_005155529.1 1813245 R 1112912 CDS YP_005155530.1 376281524 11729495 complement(1814110..1814376) 1 NC_016797.1 identified by similarity to SP:P37687; match to protein family HMM PF00462; glutaredoxin 3 1814376 grxC 11729495 grxC Brucella suis VBI22 glutaredoxin 3 YP_005155530.1 1814110 R 1112912 CDS YP_005155531.1 376281525 11729496 1814360..1814482 1 NC_016797.1 hypothetical protein 1814482 11729496 BSVBI22_A1873 Brucella suis VBI22 hypothetical protein YP_005155531.1 1814360 D 1112912 CDS YP_005155532.1 376281526 11729497 complement(1814460..1815248) 1 NC_016797.1 identified by similarity to EGAD:18112; competence protein F 1815248 11729497 BSVBI22_A1874 Brucella suis VBI22 competence protein F YP_005155532.1 1814460 R 1112912 CDS YP_005155533.1 376281527 11729498 1815431..1816324 1 NC_016797.1 identified by similarity to GP:15075644; hypothetical protein 1816324 11729498 BSVBI22_A1875 Brucella suis VBI22 hypothetical protein YP_005155533.1 1815431 D 1112912 CDS YP_005155534.1 376281528 11729499 complement(1816390..1816524) 1 NC_016797.1 hypothetical protein 1816524 11729499 BSVBI22_A1876 Brucella suis VBI22 hypothetical protein YP_005155534.1 1816390 R 1112912 CDS YP_005155535.1 376281529 11729501 complement(1817728..1818207) 1 NC_016797.1 identified by similarity to GP:14024323; hypothetical protein 1818207 11729501 BSVBI22_A1878 Brucella suis VBI22 hypothetical protein YP_005155535.1 1817728 R 1112912 CDS YP_005155536.1 376281530 11729502 1818484..1818576 1 NC_016797.1 hypothetical protein 1818576 11729502 BSVBI22_A1879 Brucella suis VBI22 hypothetical protein YP_005155536.1 1818484 D 1112912 CDS YP_005155537.1 376281531 11729503 complement(1818623..1820194) 1 NC_016797.1 identified by similarity to GP:15076107; hypothetical protein 1820194 11729503 BSVBI22_A1880 Brucella suis VBI22 hypothetical protein YP_005155537.1 1818623 R 1112912 CDS YP_005155538.1 376281532 11729504 complement(1820207..1821583) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3249; hypothetical protein 1821583 11729504 BSVBI22_A1881 Brucella suis VBI22 hypothetical protein YP_005155538.1 1820207 R 1112912 CDS YP_005155539.1 376281533 11729505 complement(1821666..1822373) 1 NC_016797.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; uroporphyrinogen-III synthase 1822373 hemD 11729505 hemD Brucella suis VBI22 uroporphyrinogen-III synthase YP_005155539.1 1821666 R 1112912 CDS YP_005155540.1 376281534 11729506 complement(1822397..1823341) 1 NC_016797.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1823341 hemC 11729506 hemC Brucella suis VBI22 porphobilinogen deaminase YP_005155540.1 1822397 R 1112912 CDS YP_005155541.1 376281535 11729507 1823460..1824539 1 NC_016797.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 1824539 gcp 11729507 gcp Brucella suis VBI22 putative DNA-binding/iron metalloprotein/AP endonuclease YP_005155541.1 1823460 D 1112912 CDS YP_005155542.1 376281536 11729508 1824536..1825516 1 NC_016797.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1825516 gpsA 11729508 gpsA Brucella suis VBI22 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_005155542.1 1824536 D 1112912 CDS YP_005155543.1 376281537 11729509 1825518..1825808 1 NC_016797.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1825808 11729509 BSVBI22_A1886 Brucella suis VBI22 YciI-like protein YP_005155543.1 1825518 D 1112912 CDS YP_005155544.1 376281538 11729510 1825821..1826249 1 NC_016797.1 identified by similarity to GP:15157855; match to protein family HMM PF04543; hypothetical protein 1826249 11729510 BSVBI22_A1887 Brucella suis VBI22 hypothetical protein YP_005155544.1 1825821 D 1112912 CDS YP_005155545.1 376281539 11729511 1826249..1826905 1 NC_016797.1 identified by similarity to GP:15076099; hypothetical protein 1826905 11729511 BSVBI22_A1888 Brucella suis VBI22 hypothetical protein YP_005155545.1 1826249 D 1112912 CDS YP_005155546.1 376281540 11729512 complement(1826951..1827808) 1 NC_016797.1 identified by match to protein family HMM PF00892; hypothetical protein 1827808 11729512 BSVBI22_A1889 Brucella suis VBI22 hypothetical protein YP_005155546.1 1826951 R 1112912 CDS YP_005155547.1 376281541 11729514 complement(1829478..1832042) 1 NC_016797.1 identified by similarity to EGAD:30442; match to protein family HMM PF01580; cell division protein FtsK 1832042 11729514 BSVBI22_A1891 Brucella suis VBI22 cell division protein FtsK YP_005155547.1 1829478 R 1112912 CDS YP_005155548.1 376281542 11729515 complement(1832252..1833553) 1 NC_016797.1 identified by similarity to GP:3136068; match to protein family HMM PF00909; match to protein family HMM TIGR00836; ammonium transporter 1833553 amt 11729515 amt Brucella suis VBI22 ammonium transporter YP_005155548.1 1832252 R 1112912 CDS YP_005155549.1 376281543 11729516 1833527..1833685 1 NC_016797.1 hypothetical protein 1833685 11729516 BSVBI22_A1893 Brucella suis VBI22 hypothetical protein YP_005155549.1 1833527 D 1112912 CDS YP_005155550.1 376281544 11729517 complement(1833742..1834677) 1 NC_016797.1 identified by similarity to SP:P23911; match to protein family HMM PF02551; match to protein family HMM TIGR00189; acyl-CoA thioesterase II 1834677 tesB 11729517 tesB Brucella suis VBI22 acyl-CoA thioesterase II YP_005155550.1 1833742 R 1112912 CDS YP_005155551.1 376281545 11729518 1834897..1836141 1 NC_016797.1 identified by match to protein family HMM PF01360; 2-octaprenyl-6-methoxyphenyl hydroxylase 1836141 11729518 BSVBI22_A1895 Brucella suis VBI22 2-octaprenyl-6-methoxyphenyl hydroxylase YP_005155551.1 1834897 D 1112912 CDS YP_005155552.1 376281546 11729519 complement(1836227..1836598) 1 NC_016797.1 identified by match to protein family HMM PF00903; glyoxalase family protein 1836598 11729519 BSVBI22_A1896 Brucella suis VBI22 glyoxalase family protein YP_005155552.1 1836227 R 1112912 CDS YP_005155553.1 376281547 11729520 complement(1836845..1837624) 1 NC_016797.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 1837624 sdhB 11729520 sdhB Brucella suis VBI22 succinate dehydrogenase iron-sulfur subunit YP_005155553.1 1836845 R 1112912 CDS YP_005155554.1 376281548 11729521 complement(1837640..1839481) 1 NC_016797.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 1839481 sdhA 11729521 sdhA Brucella suis VBI22 succinate dehydrogenase flavoprotein subunit YP_005155554.1 1837640 R 1112912 CDS YP_005155555.1 376281549 11729522 complement(1839489..1839884) 1 NC_016797.1 identified by similarity to EGAD:23053; match to protein family HMM PF01127; succinate dehydrogenase, hydrophobic membrane anchor protein 1839884 11729522 BSVBI22_A1899 Brucella suis VBI22 succinate dehydrogenase, hydrophobic membrane anchor protein YP_005155555.1 1839489 R 1112912 CDS YP_005155556.1 376281550 11729523 complement(1839898..1840296) 1 NC_016797.1 identified by similarity to EGAD:15755; match to protein family HMM PF01127; succinate dehydrogenase, cytochrome b556 subunit 1840296 sdhC 11729523 sdhC Brucella suis VBI22 succinate dehydrogenase, cytochrome b556 subunit YP_005155556.1 1839898 R 1112912 CDS YP_005155557.1 376281551 11729524 complement(1840641..1841099) 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 1841099 11729524 BSVBI22_A1901 Brucella suis VBI22 acetyltransferase YP_005155557.1 1840641 R 1112912 CDS YP_005155558.1 376281552 11729525 complement(1841356..1842765) 1 NC_016797.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1842765 leuC 11729525 leuC Brucella suis VBI22 isopropylmalate isomerase large subunit YP_005155558.1 1841356 R 1112912 CDS YP_005155559.1 376281553 11729526 complement(1842976..1843413) 1 NC_016797.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1843413 rplS 11729526 rplS Brucella suis VBI22 50S ribosomal protein L19 YP_005155559.1 1842976 R 1112912 CDS YP_005155560.1 376281554 11729527 1843705..1845168 1 NC_016797.1 identified by match to protein family HMM PF02133; NCS1 nucleoside transporter family protein 1845168 11729527 BSVBI22_A1904 Brucella suis VBI22 NCS1 nucleoside transporter family protein YP_005155560.1 1843705 D 1112912 CDS YP_005155561.1 376281555 11729529 complement(1845569..1845979) 1 NC_016797.1 identified by similarity to GP:7739616; hypothetical protein 1845979 11729529 BSVBI22_A1906 Brucella suis VBI22 hypothetical protein YP_005155561.1 1845569 R 1112912 CDS YP_005155562.1 376281556 11729530 complement(1845972..1846334) 1 NC_016797.1 identified by similarity to GP:15156392; match to protein family HMM PF03992; hypothetical protein 1846334 11729530 BSVBI22_A1907 Brucella suis VBI22 hypothetical protein YP_005155562.1 1845972 R 1112912 CDS YP_005155563.1 376281557 11729531 complement(1846331..1846654) 1 NC_016797.1 identified by similarity to GP:15156391; hypothetical protein 1846654 11729531 BSVBI22_A1908 Brucella suis VBI22 hypothetical protein YP_005155563.1 1846331 R 1112912 CDS YP_005155564.1 376281558 11729532 1846725..1847390 1 NC_016797.1 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 1847390 11729532 BSVBI22_A1909 Brucella suis VBI22 ArsR family transcriptional regulator YP_005155564.1 1846725 D 1112912 CDS YP_005155565.1 376281559 11729533 complement(1847525..1848259) 1 NC_016797.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1848259 trmD 11729533 trmD Brucella suis VBI22 tRNA (guanine-N(1)-)-methyltransferase YP_005155565.1 1847525 R 1112912 CDS YP_005155566.1 376281560 11729534 complement(1848256..1848825) 1 NC_016797.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1848825 rimM 11729534 rimM Brucella suis VBI22 16S rRNA-processing protein RimM YP_005155566.1 1848256 R 1112912 CDS YP_005155567.1 376281561 11729535 1849049..1849996 1 NC_016797.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1849996 xerC 11729535 xerC Brucella suis VBI22 site-specific tyrosine recombinase XerC YP_005155567.1 1849049 D 1112912 CDS YP_005155568.1 376281562 11729536 1850050..1851051 1 NC_016797.1 identified by similarity to GP:15157831; hypothetical protein 1851051 11729536 BSVBI22_A1913 Brucella suis VBI22 hypothetical protein YP_005155568.1 1850050 D 1112912 CDS YP_005155569.1 376281563 11729537 complement(1851255..1852658) 1 NC_016797.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1852658 lpdA-2 11729537 lpdA-2 Brucella suis VBI22 dihydrolipoamide dehydrogenase YP_005155569.1 1851255 R 1112912 CDS YP_005155570.1 376281564 11729538 complement(1852827..1853369) 1 NC_016797.1 identified by similarity to GP:14024383; hypothetical protein 1853369 11729538 BSVBI22_A1915 Brucella suis VBI22 hypothetical protein YP_005155570.1 1852827 R 1112912 CDS YP_005155571.1 376281565 11729539 complement(1853440..1854078) 1 NC_016797.1 identified by match to protein family HMM PF01810; amino acid transporter LysE 1854078 11729539 BSVBI22_A1916 Brucella suis VBI22 amino acid transporter LysE YP_005155571.1 1853440 R 1112912 CDS YP_005155572.1 376281566 11729540 complement(1854120..1854533) 1 NC_016797.1 identified by similarity to GP:15157838; match to protein family HMM PF01124; hypothetical protein 1854533 11729540 BSVBI22_A1917 Brucella suis VBI22 hypothetical protein YP_005155572.1 1854120 R 1112912 CDS YP_005155573.1 376281567 11729541 complement(1854543..1855769) 1 NC_016797.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 1855769 sucB 11729541 sucB Brucella suis VBI22 dihydrolipoamide succinyltransferase YP_005155573.1 1854543 R 1112912 CDS YP_005155574.1 376281568 11729542 complement(1855831..1858845) 1 NC_016797.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 1858845 sucA 11729542 sucA Brucella suis VBI22 2-oxoglutarate dehydrogenase E1 component YP_005155574.1 1855831 R 1112912 CDS YP_005155575.1 376281569 11729543 1858982..1859131 1 NC_016797.1 hypothetical protein 1859131 11729543 BSVBI22_A1920 Brucella suis VBI22 hypothetical protein YP_005155575.1 1858982 D 1112912 CDS YP_005155576.1 376281570 11729544 complement(1859121..1860023) 1 NC_016797.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 1860023 sucD 11729544 sucD Brucella suis VBI22 succinyl-CoA synthetase subunit alpha YP_005155576.1 1859121 R 1112912 CDS YP_005155577.1 376281571 11729545 complement(1860027..1861223) 1 NC_016797.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1861223 sucC 11729545 sucC Brucella suis VBI22 succinyl-CoA synthetase subunit beta YP_005155577.1 1860027 R 1112912 CDS YP_005155578.1 376281572 11729546 complement(1861330..1862292) 1 NC_016797.1 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 1862292 mdh 11729546 mdh Brucella suis VBI22 malate dehydrogenase YP_005155578.1 1861330 R 1112912 CDS YP_005155579.1 376281573 11729547 complement(1862412..1862654) 1 NC_016797.1 hypothetical protein 1862654 11729547 BSVBI22_A1924 Brucella suis VBI22 hypothetical protein YP_005155579.1 1862412 R 1112912 CDS YP_005155580.1 376281574 11729548 complement(1862731..1863894) 1 NC_016797.1 identified by similarity to GP:15076082; match to protein family HMM PF03969; hypothetical protein 1863894 11729548 BSVBI22_A1925 Brucella suis VBI22 hypothetical protein YP_005155580.1 1862731 R 1112912 CDS YP_005155581.1 376281575 11729549 complement(1864014..1864547) 1 NC_016797.1 identified by similarity to GP:954748; lipoprotein Omp19 1864547 omp19 11729549 omp19 Brucella suis VBI22 lipoprotein Omp19 YP_005155581.1 1864014 R 1112912 CDS YP_005155582.1 376281576 11729550 complement(1864677..1864880) 1 NC_016797.1 hypothetical protein 1864880 11729550 BSVBI22_A1927 Brucella suis VBI22 hypothetical protein YP_005155582.1 1864677 R 1112912 CDS YP_005155583.1 376281577 11729551 1864911..1865822 1 NC_016797.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1865822 dapF 11729551 dapF Brucella suis VBI22 diaminopimelate epimerase YP_005155583.1 1864911 D 1112912 CDS YP_005155584.1 376281578 11729552 1865822..1867105 1 NC_016797.1 identified by similarity to GP:15076264; match to protein family HMM PF00919; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01579; hypothetical protein 1867105 11729552 BSVBI22_A1929 Brucella suis VBI22 hypothetical protein YP_005155584.1 1865822 D 1112912 CDS YP_005155585.1 376281579 11729553 1867133..1868524 1 NC_016797.1 identified by similarity to EGAD:5681; match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; signal recognition particle-docking protein FtsY 1868524 ftsY 11729553 ftsY Brucella suis VBI22 signal recognition particle-docking protein FtsY YP_005155585.1 1867133 D 1112912 CDS YP_005155586.1 376281580 11729554 1868524..1869186 1 NC_016797.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1869186 ispZ 11729554 ispZ Brucella suis VBI22 intracellular septation protein A YP_005155586.1 1868524 D 1112912 CDS YP_005155587.1 376281581 11729555 1869219..1869992 1 NC_016797.1 identified by similarity to EGAD:35929; match to protein family HMM PF00753; hydroxyacylglutathione hydrolase 1869992 11729555 BSVBI22_A1932 Brucella suis VBI22 hydroxyacylglutathione hydrolase YP_005155587.1 1869219 D 1112912 CDS YP_005155588.1 376281582 11727328 1870039..1870530 1 NC_016797.1 hypothetical protein 1870530 11727328 BSVBI22_A1933 Brucella suis VBI22 hypothetical protein YP_005155588.1 1870039 D 1112912 CDS YP_005155589.1 376281583 11727329 complement(1870595..1870900) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2661; hypothetical protein 1870900 11727329 BSVBI22_A1934 Brucella suis VBI22 hypothetical protein YP_005155589.1 1870595 R 1112912 CDS YP_005155590.1 376281584 11727330 complement(1871012..1871428) 1 NC_016797.1 identified by similarity to EGAD:16514; match to protein family HMM PF00293; mutator mutT protein 1871428 11727330 BSVBI22_A1935 Brucella suis VBI22 mutator mutT protein YP_005155590.1 1871012 R 1112912 CDS YP_005155591.1 376281585 11727331 complement(1871425..1872216) 1 NC_016797.1 identified by match to protein family HMM PF00583; acetyltransferase 1872216 11727331 BSVBI22_A1936 Brucella suis VBI22 acetyltransferase YP_005155591.1 1871425 R 1112912 CDS YP_005155592.1 376281586 11727332 complement(1872274..1873515) 1 NC_016797.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 1873515 argJ 11727332 argJ Brucella suis VBI22 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase YP_005155592.1 1872274 R 1112912 CDS YP_005155593.1 376281587 11727333 complement(1873749..1873892) 1 NC_016797.1 hypothetical protein 1873892 11727333 BSVBI22_A1938 Brucella suis VBI22 hypothetical protein YP_005155593.1 1873749 R 1112912 CDS YP_005155594.1 376281588 11727334 complement(1873953..1874948) 1 NC_016797.1 identified by similarity to EGAD:7364; match to protein family HMM PF00639; peptidyl-prolyl cis-trans isomerase 1874948 11727334 BSVBI22_A1939 Brucella suis VBI22 peptidyl-prolyl cis-trans isomerase YP_005155594.1 1873953 R 1112912 CDS YP_005155595.1 376281589 11727335 complement(1875076..1875243) 1 NC_016797.1 hypothetical protein 1875243 11727335 BSVBI22_A1940 Brucella suis VBI22 hypothetical protein YP_005155595.1 1875076 R 1112912 CDS YP_005155596.1 376281590 11727336 1875287..1878007 1 NC_016797.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1878007 secA 11727336 secA Brucella suis VBI22 preprotein translocase subunit SecA YP_005155596.1 1875287 D 1112912 CDS YP_005155597.1 376281591 11727337 1878035..1878175 1 NC_016797.1 hypothetical protein 1878175 11727337 BSVBI22_A1942 Brucella suis VBI22 hypothetical protein YP_005155597.1 1878035 D 1112912 CDS YP_005155598.1 376281592 11727338 1878784..1880070 1 NC_016797.1 identified by similarity to GP:14023746; hypothetical protein 1880070 11727338 BSVBI22_A1943 Brucella suis VBI22 hypothetical protein YP_005155598.1 1878784 D 1112912 CDS YP_005155599.1 376281593 11727339 1880239..1881873 1 NC_016797.1 identified by match to protein family HMM PF00884; match to protein family HMM PF02418; hypothetical protein 1881873 11727339 BSVBI22_A1944 Brucella suis VBI22 hypothetical protein YP_005155599.1 1880239 D 1112912 CDS YP_005155600.1 376281594 11727340 1882227..1882328 1 NC_016797.1 hypothetical protein 1882328 11727340 BSVBI22_A1945 Brucella suis VBI22 hypothetical protein YP_005155600.1 1882227 D 1112912 CDS YP_005155601.1 376281595 11727342 complement(1882711..1882920) 1 NC_016797.1 hypothetical protein 1882920 11727342 BSVBI22_A1946 Brucella suis VBI22 hypothetical protein YP_005155601.1 1882711 R 1112912 CDS YP_005155602.1 376281596 11727343 complement(1883041..1884024) 1 NC_016797.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1884024 11727343 BSVBI22_A1947 Brucella suis VBI22 LysR family transcriptional regulator YP_005155602.1 1883041 R 1112912 CDS YP_005155603.1 376281597 11727344 complement(1884064..1884249) 1 NC_016797.1 hypothetical protein 1884249 11727344 BSVBI22_A1948 Brucella suis VBI22 hypothetical protein YP_005155603.1 1884064 R 1112912 CDS YP_005155604.1 376281598 11727345 1884315..1885160 1 NC_016797.1 identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 1885160 11727345 BSVBI22_A1949 Brucella suis VBI22 amino acid ABC transporter substrate-binding protein YP_005155604.1 1884315 D 1112912 CDS YP_005155605.1 376281599 11727347 1885951..1886673 1 NC_016797.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 1886673 11727347 BSVBI22_A1951 Brucella suis VBI22 amino acid ABC transporter permease YP_005155605.1 1885951 D 1112912 CDS YP_005155606.1 376281600 11727348 1886670..1887485 1 NC_016797.1 identified by match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 1887485 11727348 BSVBI22_A1952 Brucella suis VBI22 amino acid ABC transporter ATP-binding protein YP_005155606.1 1886670 D 1112912 CDS YP_005155607.1 376281601 11727349 1887506..1888519 1 NC_016797.1 identified by match to protein family HMM PF00491; arginase family protein 1888519 11727349 BSVBI22_A1953 Brucella suis VBI22 arginase family protein YP_005155607.1 1887506 D 1112912 CDS YP_005155608.1 376281602 11727351 1888528..1889979 1 NC_016797.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1889979 aspA 11727351 aspA Brucella suis VBI22 aspartate ammonia-lyase YP_005155608.1 1888528 D 1112912 CDS YP_005155609.1 376281603 11727352 1889963..1890718 1 NC_016797.1 identified by similarity to EGAD:31037; match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 1890718 11727352 BSVBI22_A1955 Brucella suis VBI22 amino acid ABC transporter ATP-binding protein YP_005155609.1 1889963 D 1112912 CDS YP_005155610.1 376281604 11727353 1890727..1891725 1 NC_016797.1 identified by similarity to EGAD:14317; match to protein family HMM PF00710; L-asparaginase type II 1891725 11727353 BSVBI22_A1956 Brucella suis VBI22 L-asparaginase type II YP_005155610.1 1890727 D 1112912 CDS YP_005155611.1 376281605 11727354 complement(1891862..1892545) 1 NC_016797.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1892545 11727354 BSVBI22_A1957 Brucella suis VBI22 GntR family transcriptional regulator YP_005155611.1 1891862 R 1112912 CDS YP_005155612.1 376281606 11727355 complement(1892569..1893558) 1 NC_016797.1 identified by similarity to SP:P43843; match to protein family HMM PF00710; asparaginase family protein 1893558 11727355 BSVBI22_A1958 Brucella suis VBI22 asparaginase family protein YP_005155612.1 1892569 R 1112912 CDS YP_005155613.1 376281607 11727356 1893636..1894943 1 NC_016797.1 identified by match to protein family HMM PF00083; major facilitator family transporter 1894943 11727356 BSVBI22_A1959 Brucella suis VBI22 major facilitator family transporter YP_005155613.1 1893636 D 1112912 CDS YP_005155614.1 376281608 11727357 complement(1895430..1895582) 1 NC_016797.1 hypothetical protein 1895582 11727357 BSVBI22_A1960 Brucella suis VBI22 hypothetical protein YP_005155614.1 1895430 R 1112912 CDS YP_005155615.1 376281609 11727358 complement(1895629..1896912) 1 NC_016797.1 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; methionine gamma-lyase 1896912 11727358 BSVBI22_A1961 Brucella suis VBI22 methionine gamma-lyase YP_005155615.1 1895629 R 1112912 CDS YP_005155616.1 376281610 11727359 complement(1897092..1897541) 1 NC_016797.1 identified by match to protein family HMM PF00582; universal stress protein 1897541 11727359 BSVBI22_A1962 Brucella suis VBI22 universal stress protein YP_005155616.1 1897092 R 1112912 CDS YP_005155617.1 376281611 11727361 complement(1898853..1899101) 1 NC_016797.1 hypothetical protein 1899101 11727361 BSVBI22_A1964 Brucella suis VBI22 hypothetical protein YP_005155617.1 1898853 R 1112912 CDS YP_005155618.1 376281612 11727362 complement(1899261..1900136) 1 NC_016797.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 1900136 hbd 11727362 hbd Brucella suis VBI22 3-hydroxybutyryl-CoA dehydrogenase YP_005155618.1 1899261 R 1112912 CDS YP_005155619.1 376281613 11727363 complement(1900620..1901549) 1 NC_016797.1 identified by similarity to SP:P38974; match to protein family HMM PF00766; electron transfer flavoprotein subunit alpha 1901549 etfA 11727363 etfA Brucella suis VBI22 electron transfer flavoprotein subunit alpha YP_005155619.1 1900620 R 1112912 CDS YP_005155620.1 376281614 11727364 complement(1901702..1902448) 1 NC_016797.1 identified by similarity to EGAD:17375; match to protein family HMM PF01012; electron transfer flavoprotein subunit beta 1902448 etfB 11727364 etfB Brucella suis VBI22 electron transfer flavoprotein subunit beta YP_005155620.1 1901702 R 1112912 CDS YP_005155621.1 376281615 11727365 1902784..1903482 1 NC_016797.1 identified by match to protein family HMM TIGR00364; exsB protein 1903482 11727365 BSVBI22_A1968 Brucella suis VBI22 exsB protein YP_005155621.1 1902784 D 1112912 CDS YP_005155622.1 376281616 11727366 1903482..1903847 1 NC_016797.1 identified by match to protein family HMM PF01242; 6-pyruvoyl tetrahydrobiopterin synthase 1903847 11727366 BSVBI22_A1969 Brucella suis VBI22 6-pyruvoyl tetrahydrobiopterin synthase YP_005155622.1 1903482 D 1112912 CDS YP_005155623.1 376281617 11727367 1903847..1904602 1 NC_016797.1 identified by match to protein family HMM PF04055; radical activating enzyme 1904602 11727367 BSVBI22_A1970 Brucella suis VBI22 radical activating enzyme YP_005155623.1 1903847 D 1112912 CDS YP_005155624.1 376281618 11727368 complement(1904739..1905326) 1 NC_016797.1 identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636; ATP:cob(I)alamin adenosyltransferase 1905326 11727368 BSVBI22_A1971 Brucella suis VBI22 ATP:cob(I)alamin adenosyltransferase YP_005155624.1 1904739 R 1112912 CDS YP_005155625.1 376281619 11727369 complement(1905328..1905495) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2682; hypothetical protein 1905495 11727369 BSVBI22_A1972 Brucella suis VBI22 hypothetical protein YP_005155625.1 1905328 R 1112912 CDS YP_005155626.1 376281620 11727370 complement(1905561..1906403) 1 NC_016797.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 1906403 11727370 BSVBI22_A1973 Brucella suis VBI22 short chain dehydrogenase YP_005155626.1 1905561 R 1112912 CDS YP_005155627.1 376281621 11727371 1906561..1907421 1 NC_016797.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00765; ribonuclease BN 1907421 11727371 BSVBI22_A1974 Brucella suis VBI22 ribonuclease BN YP_005155627.1 1906561 D 1112912 CDS YP_005155628.1 376281622 11727372 1907439..1907924 1 NC_016797.1 identified by match to protein family HMM PF02639; hypothetical protein 1907924 11727372 BSVBI22_A1975 Brucella suis VBI22 hypothetical protein YP_005155628.1 1907439 D 1112912 CDS YP_005155629.1 376281623 11727373 complement(1907932..1908648) 1 NC_016797.1 thiol:disulfide interchange protein 1908648 11727373 BSVBI22_A1976 Brucella suis VBI22 thiol:disulfide interchange protein YP_005155629.1 1907932 R 1112912 CDS YP_005155630.1 376281624 11727374 1908702..1910102 1 NC_016797.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 1910102 argH 11727374 argH Brucella suis VBI22 argininosuccinate lyase YP_005155630.1 1908702 D 1112912 CDS YP_005155631.1 376281625 11727375 1910207..1910395 1 NC_016797.1 hypothetical protein 1910395 11727375 BSVBI22_A1978 Brucella suis VBI22 hypothetical protein YP_005155631.1 1910207 D 1112912 CDS YP_005155632.1 376281626 11727376 1910423..1911688 1 NC_016797.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; match to protein family HMM TIGR01048; diaminopimelate decarboxylase 1911688 lysA 11727376 lysA Brucella suis VBI22 diaminopimelate decarboxylase YP_005155632.1 1910423 D 1112912 CDS YP_005155633.1 376281627 11727377 1911787..1914432 1 NC_016797.1 identified by similarity to GP:15075674; hypothetical protein 1914432 11727377 BSVBI22_A1980 Brucella suis VBI22 hypothetical protein YP_005155633.1 1911787 D 1112912 CDS YP_005155634.1 376281628 11727378 complement(1914472..1915008) 1 NC_016797.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 1915008 hpt 11727378 hpt Brucella suis VBI22 hypoxanthine-guanine phosphoribosyltransferase YP_005155634.1 1914472 R 1112912 CDS YP_005155635.1 376281629 11727379 1915157..1915936 1 NC_016797.1 identified by similarity to GP:15075687; hypothetical protein 1915936 11727379 BSVBI22_A1982 Brucella suis VBI22 hypothetical protein YP_005155635.1 1915157 D 1112912 CDS YP_005155636.1 376281630 11727380 1916090..1917187 1 NC_016797.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1917187 hisC 11727380 hisC Brucella suis VBI22 histidinol-phosphate aminotransferase YP_005155636.1 1916090 D 1112912 CDS YP_005155637.1 376281631 11727381 1917192..1918157 1 NC_016797.1 dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate; cyclohexadienyl dehydrogenase 1918157 tyrC 11727381 tyrC Brucella suis VBI22 cyclohexadienyl dehydrogenase YP_005155637.1 1917192 D 1112912 CDS YP_005155638.1 376281632 11727382 complement(1918126..1919145) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2723; hypothetical protein 1919145 11727382 BSVBI22_A1985 Brucella suis VBI22 hypothetical protein YP_005155638.1 1918126 R 1112912 CDS YP_005155639.1 376281633 11727383 complement(1919165..1919368) 1 NC_016797.1 hypothetical protein 1919368 11727383 BSVBI22_A1986 Brucella suis VBI22 hypothetical protein YP_005155639.1 1919165 R 1112912 CDS YP_005155640.1 376281634 11727384 1919357..1919917 1 NC_016797.1 identified by similarity to SP:P39163; match to protein family HMM PF04752; cation transport protein 1919917 11727384 BSVBI22_A1987 Brucella suis VBI22 cation transport protein YP_005155640.1 1919357 D 1112912 CDS YP_005155641.1 376281635 11727386 1920250..1920540 1 NC_016797.1 identified by similarity to EGAD:140445; match to protein family HMM PF02325; hypothetical protein 1920540 11727386 BSVBI22_A1988 Brucella suis VBI22 hypothetical protein YP_005155641.1 1920250 D 1112912 CDS YP_005155642.1 376281636 11727387 complement(1920711..1921241) 1 NC_016797.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 1921241 ppa 11727387 ppa Brucella suis VBI22 inorganic pyrophosphatase YP_005155642.1 1920711 R 1112912 CDS YP_005155643.1 376281637 11727388 complement(1921394..1922176) 1 NC_016797.1 identified by match to protein family HMM PF01553; 1-acyl-sn-glycerol-3-phosphate acyltransferase 1922176 11727388 BSVBI22_A1990 Brucella suis VBI22 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_005155643.1 1921394 R 1112912 CDS YP_005155644.1 376281638 11727389 complement(1922355..1922993) 1 NC_016797.1 identified by similarity to GP:15075681; hypothetical protein 1922993 11727389 BSVBI22_A1991 Brucella suis VBI22 hypothetical protein YP_005155644.1 1922355 R 1112912 CDS YP_005155645.1 376281639 11727390 complement(1923254..1924255) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2714; hypothetical protein 1924255 11727390 BSVBI22_A1992 Brucella suis VBI22 hypothetical protein YP_005155645.1 1923254 R 1112912 CDS YP_005155646.1 376281640 11727391 complement(1924248..1924907) 1 NC_016797.1 identified by similarity to EGAD:7038; match to protein family HMM PF00005; ABC transporter ATP-binding protein 1924907 ftsE 11727391 ftsE Brucella suis VBI22 ABC transporter ATP-binding protein YP_005155646.1 1924248 R 1112912 CDS YP_005155647.1 376281641 11727392 complement(1924912..1925094) 1 NC_016797.1 hypothetical protein 1925094 11727392 BSVBI22_A1994 Brucella suis VBI22 hypothetical protein YP_005155647.1 1924912 R 1112912 CDS YP_005155648.1 376281642 11727393 1925163..1925582 1 NC_016797.1 hypothetical protein 1925582 11727393 BSVBI22_A1995 Brucella suis VBI22 hypothetical protein YP_005155648.1 1925163 D 1112912 CDS YP_005155649.1 376281643 11727395 complement(1925619..1925720) 1 NC_016797.1 hypothetical protein 1925720 11727395 BSVBI22_A1996 Brucella suis VBI22 hypothetical protein YP_005155649.1 1925619 R 1112912 CDS YP_005155650.1 376281644 11727396 1925966..1926652 1 NC_016797.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 1926652 aqpZ 11727396 aqpZ Brucella suis VBI22 aquaporin Z YP_005155650.1 1925966 D 1112912 CDS YP_005155651.1 376281645 11727397 complement(1926653..1926784) 1 NC_016797.1 hypothetical protein 1926784 11727397 BSVBI22_A1998 Brucella suis VBI22 hypothetical protein YP_005155651.1 1926653 R 1112912 CDS YP_005155652.1 376281646 11727398 1927036..1927728 1 NC_016797.1 identified by similarity to GP:15157980; hypothetical protein 1927728 11727398 BSVBI22_A1999 Brucella suis VBI22 hypothetical protein YP_005155652.1 1927036 D 1112912 CDS YP_005155653.1 376281647 11727399 1927831..1928637 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3264; match to protein family HMM PF03372; match to protein family HMM TIGR00633; exodeoxyribonuclease III 1928637 xth-2 11727399 xth-2 Brucella suis VBI22 exodeoxyribonuclease III YP_005155653.1 1927831 D 1112912 CDS YP_005155654.1 376281648 11727400 complement(1928643..1929104) 1 NC_016797.1 identified by match to protein family HMM PF00027; cyclic nucleotide-binding protein 1929104 11727400 BSVBI22_A2001 Brucella suis VBI22 cyclic nucleotide-binding protein YP_005155654.1 1928643 R 1112912 CDS YP_005155655.1 376281649 11727401 complement(1929139..1929822) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3262; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 1929822 11727401 BSVBI22_A2002 Brucella suis VBI22 DNA-binding response regulator YP_005155655.1 1929139 R 1112912 CDS YP_005155656.1 376281650 11727402 1930072..1930575 1 NC_016797.1 identified by similarity to GP:14024337; hypothetical protein 1930575 11727402 BSVBI22_A2003 Brucella suis VBI22 hypothetical protein YP_005155656.1 1930072 D 1112912 CDS YP_005155657.1 376281651 11727403 1930636..1930935 1 NC_016797.1 hypothetical protein 1930935 11727403 BSVBI22_A2004 Brucella suis VBI22 hypothetical protein YP_005155657.1 1930636 D 1112912 CDS YP_005155658.1 376281652 11727404 complement(1930964..1932487) 1 NC_016797.1 intimin/invasin family protein 1932487 11727404 BSVBI22_A2005 Brucella suis VBI22 intimin/invasin family protein YP_005155658.1 1930964 R 1112912 CDS YP_005155659.1 376281653 11727405 complement(1932484..1933563) 1 NC_016797.1 hypothetical protein 1933563 11727405 BSVBI22_A2006 Brucella suis VBI22 hypothetical protein YP_005155659.1 1932484 R 1112912 CDS YP_005155660.1 376281654 11727406 1933890..1934279 1 NC_016797.1 hypothetical protein 1934279 11727406 BSVBI22_A2007 Brucella suis VBI22 hypothetical protein YP_005155660.1 1933890 D 1112912 CDS YP_005155661.1 376281655 11727407 complement(1934366..1935922) 1 NC_016797.1 hypothetical protein 1935922 11727407 BSVBI22_A2008 Brucella suis VBI22 hypothetical protein YP_005155661.1 1934366 R 1112912 CDS YP_005155662.1 376281656 11727408 1936107..1939166 1 NC_016797.1 identified by similarity to GI:260567512; contains PRK14849 domain; outer membrane autotransporter barrel domain-containing protein 1939166 11727408 BSVBI22_A2009 Brucella suis VBI22 outer membrane autotransporter barrel domain-containing protein YP_005155662.1 1936107 D 1112912 CDS YP_005155663.1 376281657 11727409 complement(1941027..1941698) 1 NC_016797.1 identified by similarity to GP:15075693; match to protein family HMM PF02592; match to protein family HMM TIGR00697; hypothetical protein 1941698 11727409 BSVBI22_A2010 Brucella suis VBI22 hypothetical protein YP_005155663.1 1941027 R 1112912 CDS YP_005155664.1 376281658 11727410 complement(1941778..1942071) 1 NC_016797.1 required for 70S ribosome assembly; 50S ribosomal protein L28 1942071 rpmB 11727410 rpmB Brucella suis VBI22 50S ribosomal protein L28 YP_005155664.1 1941778 R 1112912 CDS YP_005155665.1 376281659 11727411 1942433..1943248 1 NC_016797.1 identified by similarity to OMNI:NTL02ML2738; hypothetical protein 1943248 11727411 BSVBI22_A2012 Brucella suis VBI22 hypothetical protein YP_005155665.1 1942433 D 1112912 CDS YP_005155666.1 376281660 11727412 complement(1943360..1943782) 1 NC_016797.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 1943782 11727412 BSVBI22_A2013 Brucella suis VBI22 MerR family transcriptional regulator YP_005155666.1 1943360 R 1112912 CDS YP_005155667.1 376281661 11727413 1943871..1946315 1 NC_016797.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525; cadmium-translocating P-type ATPase 1946315 cadA-1 11727413 cadA-1 Brucella suis VBI22 cadmium-translocating P-type ATPase YP_005155667.1 1943871 D 1112912 CDS YP_005155668.1 376281662 11727414 1946722..1947471 1 NC_016797.1 identified by similarity to GP:15141324; hypothetical protein 1947471 11727414 BSVBI22_A2015 Brucella suis VBI22 hypothetical protein YP_005155668.1 1946722 D 1112912 CDS YP_005155669.1 376281663 11727415 1947498..1948583 1 NC_016797.1 hypothetical protein 1948583 11727415 BSVBI22_A2016 Brucella suis VBI22 hypothetical protein YP_005155669.1 1947498 D 1112912 CDS YP_005155670.1 376281664 11727416 complement(1948756..1950657) 1 NC_016797.1 identified by similarity to SP:P29934; match to protein family HMM TIGR01651; cobalamin biosynthesis protein 1950657 11727416 BSVBI22_A2017 Brucella suis VBI22 cobalamin biosynthesis protein YP_005155670.1 1948756 R 1112912 CDS YP_005155671.1 376281665 11727417 complement(1950765..1951751) 1 NC_016797.1 identified by similarity to SP:P29933; match to protein family HMM TIGR01650; cobalamin biosynthesis protein 1951751 11727417 BSVBI22_A2018 Brucella suis VBI22 cobalamin biosynthesis protein YP_005155671.1 1950765 R 1112912 CDS YP_005155672.1 376281666 11727418 1951830..1952060 1 NC_016797.1 hypothetical protein 1952060 11727418 BSVBI22_A2019 Brucella suis VBI22 hypothetical protein YP_005155672.1 1951830 D 1112912 CDS YP_005155673.1 376281667 11727419 complement(1952038..1952667) 1 NC_016797.1 identified by match to protein family HMM PF00226; DnaJ domain-containing protein 1952667 11727419 BSVBI22_A2020 Brucella suis VBI22 DnaJ domain-containing protein YP_005155673.1 1952038 R 1112912 CDS YP_005155674.1 376281668 11727420 complement(1952664..1952861) 1 NC_016797.1 hypothetical protein 1952861 11727420 BSVBI22_A2021 Brucella suis VBI22 hypothetical protein YP_005155674.1 1952664 R 1112912 CDS YP_005155675.1 376281669 11727421 1952854..1953168 1 NC_016797.1 identified by similarity to SP:P15298; match to protein family HMM PF01722; bolA protein 1953168 bolA 11727421 bolA Brucella suis VBI22 bolA protein YP_005155675.1 1952854 D 1112912 CDS YP_005155676.1 376281670 11727422 complement(1953193..1954500) 1 NC_016797.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; hypothetical protein 1954500 11727422 BSVBI22_A2023 Brucella suis VBI22 hypothetical protein YP_005155676.1 1953193 R 1112912 CDS YP_005155677.1 376281671 11727423 complement(1954564..1955700) 1 NC_016797.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1955700 aroB 11727423 aroB Brucella suis VBI22 3-dehydroquinate synthase YP_005155677.1 1954564 R 1112912 CDS YP_005155678.1 376281672 11727424 complement(1955793..1956395) 1 NC_016797.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 1956395 aroK 11727424 aroK Brucella suis VBI22 shikimate kinase YP_005155678.1 1955793 R 1112912 CDS YP_005155679.1 376281673 11727425 1956520..1956726 1 NC_016797.1 hypothetical protein 1956726 11727425 BSVBI22_A2026 Brucella suis VBI22 hypothetical protein YP_005155679.1 1956520 D 1112912 CDS YP_005155680.1 376281674 11727426 1956729..1957652 1 NC_016797.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1957652 xerD 11727426 xerD Brucella suis VBI22 site-specific tyrosine recombinase XerD YP_005155680.1 1956729 D 1112912 CDS YP_005155681.1 376281675 11727427 1957791..1958744 1 NC_016797.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1958744 accA 11727427 accA Brucella suis VBI22 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_005155681.1 1957791 D 1112912 CDS YP_005155682.1 376281676 11727428 1958966..1960177 1 NC_016797.1 identified by similarity to GP:15159690; putative lipoprotein 1960177 11727428 BSVBI22_A2029 Brucella suis VBI22 putative lipoprotein YP_005155682.1 1958966 D 1112912 CDS YP_005155683.1 376281677 11727429 1960156..1960413 1 NC_016797.1 identified by similarity to GP:15075708; match to protein family HMM PF01206; hypothetical protein 1960413 11727429 BSVBI22_A2030 Brucella suis VBI22 hypothetical protein YP_005155683.1 1960156 D 1112912 CDS YP_005155684.1 376281678 11727430 complement(1960431..1961603) 1 NC_016797.1 identified by match to protein family HMM PF02492; cobalamin synthesis protein/P47K family protein 1961603 11727430 BSVBI22_A2031 Brucella suis VBI22 cobalamin synthesis protein/P47K family protein YP_005155684.1 1960431 R 1112912 CDS YP_005155685.1 376281679 11727431 complement(1961605..1962720) 1 NC_016797.1 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 1962720 11727431 BSVBI22_A2032 Brucella suis VBI22 D-alanyl-D-alanine carboxypeptidase YP_005155685.1 1961605 R 1112912 CDS YP_005155686.1 376281680 11727432 1963015..1964178 1 NC_016797.1 identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; M20/M25/M40 family peptidase 1964178 11727432 BSVBI22_A2033 Brucella suis VBI22 M20/M25/M40 family peptidase YP_005155686.1 1963015 D 1112912 CDS YP_005155687.1 376281681 11727433 1964175..1964309 1 NC_016797.1 hypothetical protein 1964309 11727433 BSVBI22_A2034 Brucella suis VBI22 hypothetical protein YP_005155687.1 1964175 D 1112912 CDS YP_005155688.1 376281682 11727435 complement(1964377..1965141) 1 NC_016797.1 identified by similarity to EGAD:23256; match to protein family HMM PF00106; glucose 1-dehydrogenase 1965141 11727435 BSVBI22_A2035 Brucella suis VBI22 glucose 1-dehydrogenase YP_005155688.1 1964377 R 1112912 CDS YP_005155689.1 376281683 11727436 1965249..1965683 1 NC_016797.1 identified by similarity to GP:15157579; match to protein family HMM PF04828; hypothetical protein 1965683 11727436 BSVBI22_A2036 Brucella suis VBI22 hypothetical protein YP_005155689.1 1965249 D 1112912 CDS YP_005155690.1 376281684 11727437 1965833..1966177 1 NC_016797.1 identified by similarity to OMNI:NTL03PA01934; hypothetical protein 1966177 11727437 BSVBI22_A2037 Brucella suis VBI22 hypothetical protein YP_005155690.1 1965833 D 1112912 CDS YP_005155691.1 376281685 11727438 complement(1966247..1967881) 1 NC_016797.1 identified by similarity to EGAD:149670; match to protein family HMM PF00732; match to protein family HMM PF05199; L-sorbose dehydrogenase 1967881 11727438 BSVBI22_A2038 Brucella suis VBI22 L-sorbose dehydrogenase YP_005155691.1 1966247 R 1112912 CDS YP_005155692.1 376281686 11727439 complement(1967892..1968656) 1 NC_016797.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1968656 fabG 11727439 fabG Brucella suis VBI22 3-ketoacyl-ACP reductase YP_005155692.1 1967892 R 1112912 CDS YP_005155693.1 376281687 11727440 complement(1968653..1970137) 1 NC_016797.1 GMC family oxidoreductase 1970137 11727440 BSVBI22_A2040 Brucella suis VBI22 GMC family oxidoreductase YP_005155693.1 1968653 R 1112912 CDS YP_005155694.1 376281688 11727441 complement(1970150..1971670) 1 NC_016797.1 identified by similarity to EGAD:149672; match to protein family HMM PF00171; L-sorbosone dehydrogenase, NAD(P) dependent 1971670 11727441 BSVBI22_A2041 Brucella suis VBI22 L-sorbosone dehydrogenase, NAD(P) dependent YP_005155694.1 1970150 R 1112912 CDS YP_005155695.1 376281689 11727442 complement(1971664..1972440) 1 NC_016797.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase family protein 1972440 11727442 BSVBI22_A2042 Brucella suis VBI22 enoyl-CoA hydratase/isomerase family protein YP_005155695.1 1971664 R 1112912 CDS YP_005155696.1 376281690 11727443 complement(1972442..1974043) 1 NC_016797.1 identified by match to protein family HMM PF01144; acetyl-CoA-transferase subunit, putative 1974043 11727443 BSVBI22_A2043 Brucella suis VBI22 acetyl-CoA-transferase subunit, putative YP_005155696.1 1972442 R 1112912 CDS YP_005155697.1 376281691 11727444 complement(1974049..1975050) 1 NC_016797.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 1975050 11727444 BSVBI22_A2044 Brucella suis VBI22 Gfo/Idh/MocA family oxidoreductase YP_005155697.1 1974049 R 1112912 CDS YP_005155698.1 376281692 11727445 complement(1975029..1976087) 1 NC_016797.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcriptional regulator 1976087 11727445 BSVBI22_A2045 Brucella suis VBI22 LacI family transcriptional regulator YP_005155698.1 1975029 R 1112912 CDS YP_005155699.1 376281693 11727446 1976338..1977507 1 NC_016797.1 identified by similarity to GP:15076333; hypothetical protein 1977507 11727446 BSVBI22_A2046 Brucella suis VBI22 hypothetical protein YP_005155699.1 1976338 D 1112912 CDS YP_005155700.1 376281694 11727447 complement(1977541..1978563) 1 NC_016797.1 identified by match to protein family HMM PF00296; luciferase family protein 1978563 11727447 BSVBI22_A2047 Brucella suis VBI22 luciferase family protein YP_005155700.1 1977541 R 1112912 CDS YP_005155701.1 376281695 11727448 complement(1978560..1978769) 1 NC_016797.1 hypothetical protein 1978769 11727448 BSVBI22_A2048 Brucella suis VBI22 hypothetical protein YP_005155701.1 1978560 R 1112912 CDS YP_005155702.1 376281696 11727449 1978832..1979797 1 NC_016797.1 identified by similarity to GP:15076239; match to protein family HMM PF04392; ABC transporter periplasmic substrate-binding protein 1979797 11727449 BSVBI22_A2049 Brucella suis VBI22 ABC transporter periplasmic substrate-binding protein YP_005155702.1 1978832 D 1112912 CDS YP_005155703.1 376281697 11727450 complement(1980001..1980261) 1 NC_016797.1 hypothetical protein 1980261 11727450 BSVBI22_A2050 Brucella suis VBI22 hypothetical protein YP_005155703.1 1980001 R 1112912 CDS YP_005155704.1 376281698 11727451 1980441..1981325 1 NC_016797.1 identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 1981325 11727451 BSVBI22_A2051 Brucella suis VBI22 branched-chain amino acid ABC transporter permease YP_005155704.1 1980441 D 1112912 CDS YP_005155705.1 376281699 11727452 1981322..1982116 1 NC_016797.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1982116 11727452 BSVBI22_A2052 Brucella suis VBI22 ABC transporter ATP-binding protein YP_005155705.1 1981322 D 1112912 CDS YP_005155706.1 376281700 11727453 1982278..1983321 1 NC_016797.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1983321 holA 11727453 holA Brucella suis VBI22 DNA polymerase III subunit delta YP_005155706.1 1982278 D 1112912 CDS YP_005155707.1 376281701 11727454 complement(1983415..1984296) 1 NC_016797.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; chromosome partitioning protein ParB 1984296 parB 11727454 parB Brucella suis VBI22 chromosome partitioning protein ParB YP_005155707.1 1983415 R 1112912 CDS YP_005155708.1 376281702 11727455 complement(1984340..1985137) 1 NC_016797.1 identified by similarity to SP:O05189; match to protein family HMM PF00991; chromosome partitioning protein ParA 1985137 parA 11727455 parA Brucella suis VBI22 chromosome partitioning protein ParA YP_005155708.1 1984340 R 1112912 CDS YP_005155709.1 376281703 11727456 complement(1985190..1985831) 1 NC_016797.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1985831 gidB 11727456 gidB Brucella suis VBI22 16S rRNA methyltransferase GidB YP_005155709.1 1985190 R 1112912 CDS YP_005155710.1 376281704 11727457 complement(1985828..1987738) 1 NC_016797.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 1987738 gidA 11727457 gidA Brucella suis VBI22 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_005155710.1 1985828 R 1112912 CDS YP_005155711.1 376281705 11727458 complement(1987965..1989293) 1 NC_016797.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1989293 trmE 11727458 trmE Brucella suis VBI22 tRNA modification GTPase TrmE YP_005155711.1 1987965 R 1112912 CDS YP_005155712.1 376281706 11727459 1989408..1991408 1 NC_016797.1 identified by similarity to GP:14024528; match to protein family HMM PF03190; hypothetical protein 1991408 11727459 BSVBI22_A2059 Brucella suis VBI22 hypothetical protein YP_005155712.1 1989408 D 1112912 CDS YP_005155713.1 376281707 11727460 complement(1991493..1992758) 1 NC_016797.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1992758 rho 11727460 rho Brucella suis VBI22 transcription termination factor Rho YP_005155713.1 1991493 R 1112912 CDS YP_005155714.1 376281708 11727461 complement(1993140..1993676) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3455; match to protein family HMM PF03653; match to protein family HMM TIGR00701; hypothetical protein 1993676 11727461 BSVBI22_A2061 Brucella suis VBI22 hypothetical protein YP_005155714.1 1993140 R 1112912 CDS YP_005155715.1 376281709 11727462 complement(1993673..1994698) 1 NC_016797.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 1994698 hemE 11727462 hemE Brucella suis VBI22 uroporphyrinogen decarboxylase YP_005155715.1 1993673 R 1112912 CDS YP_005155716.1 376281710 11727463 1995151..1995990 1 NC_016797.1 identified by similarity to GP:14024532; match to protein family HMM PF03618; hypothetical protein 1995990 11727463 BSVBI22_A2063 Brucella suis VBI22 hypothetical protein YP_005155716.1 1995151 D 1112912 CDS YP_005155717.1 376281711 11727464 1995987..1996586 1 NC_016797.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1996586 maf 11727464 maf Brucella suis VBI22 Maf-like protein YP_005155717.1 1995987 D 1112912 CDS YP_005155718.1 376281712 11727465 1996594..1997448 1 NC_016797.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1997448 aroE 11727465 aroE Brucella suis VBI22 shikimate 5-dehydrogenase YP_005155718.1 1996594 D 1112912 CDS YP_005155719.1 376281713 11727466 1997445..1998047 1 NC_016797.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1998047 coaE 11727466 coaE Brucella suis VBI22 dephospho-CoA kinase YP_005155719.1 1997445 D 1112912 CDS YP_005155720.1 376281714 11727467 1998089..1998793 1 NC_016797.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1998793 dnaQ 11727467 dnaQ Brucella suis VBI22 DNA polymerase III subunit epsilon YP_005155720.1 1998089 D 1112912 CDS YP_005155721.1 376281715 11727468 complement(1998852..1999343) 1 NC_016797.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 1999343 secB 11727468 secB Brucella suis VBI22 preprotein translocase subunit SecB YP_005155721.1 1998852 R 1112912 CDS YP_005155722.1 376281716 11727469 complement(1999463..1999960) 1 NC_016797.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 1999960 fxsA 11727469 fxsA Brucella suis VBI22 FxsA protein YP_005155722.1 1999463 R 1112912 CDS YP_005155723.1 376281717 11727470 2000165..2000872 1 NC_016797.1 identified by similarity to GP:15154866; hypothetical protein 2000872 11727470 BSVBI22_A2070 Brucella suis VBI22 hypothetical protein YP_005155723.1 2000165 D 1112912 CDS YP_005155724.1 376281718 11727471 2000936..2002045 1 NC_016797.1 identified by match to protein family HMM PF03562; transglycosylase 2002045 11727471 BSVBI22_A2071 Brucella suis VBI22 transglycosylase YP_005155724.1 2000936 D 1112912 CDS YP_005155725.1 376281719 11727472 2002051..2002653 1 NC_016797.1 identified by match to protein family HMM PF01713; Smr family protein 2002653 11727472 BSVBI22_A2072 Brucella suis VBI22 Smr family protein YP_005155725.1 2002051 D 1112912 CDS YP_005155726.1 376281720 11727473 2002650..2003030 1 NC_016797.1 identified by similarity to GP:15154869; match to protein family HMM PF01381; hypothetical protein 2003030 11727473 BSVBI22_A2073 Brucella suis VBI22 hypothetical protein YP_005155726.1 2002650 D 1112912 CDS YP_005155727.1 376281721 11727474 complement(2003039..2003968) 1 NC_016797.1 identified by similarity to GP:15154911; hypothetical protein 2003968 11727474 BSVBI22_A2074 Brucella suis VBI22 hypothetical protein YP_005155727.1 2003039 R 1112912 CDS YP_005155728.1 376281722 11727475 complement(2004205..2005509) 1 NC_016797.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 2005509 hslU 11727475 hslU Brucella suis VBI22 ATP-dependent protease ATP-binding subunit HslU YP_005155728.1 2004205 R 1112912 CDS YP_005155729.1 376281723 11727476 complement(2005583..2006137) 1 NC_016797.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 2006137 hslV 11727476 hslV Brucella suis VBI22 ATP-dependent protease peptidase subunit YP_005155729.1 2005583 R 1112912 CDS YP_005155730.1 376281724 11727477 2006434..2007042 1 NC_016797.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 2007042 hisB 11727477 hisB Brucella suis VBI22 imidazoleglycerol-phosphate dehydratase YP_005155730.1 2006434 D 1112912 CDS YP_005155731.1 376281725 11727478 2007154..2007663 1 NC_016797.1 identified by similarity to GP:15072982; hypothetical protein 2007663 11727478 BSVBI22_A2078 Brucella suis VBI22 hypothetical protein YP_005155731.1 2007154 D 1112912 CDS YP_005155732.1 376281726 11727479 2007666..2008316 1 NC_016797.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2008316 hisH 11727479 hisH Brucella suis VBI22 imidazole glycerol phosphate synthase subunit HisH YP_005155732.1 2007666 D 1112912 CDS YP_005155733.1 376281727 11727480 2008321..2009052 1 NC_016797.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2009052 hisA 11727480 hisA Brucella suis VBI22 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_005155733.1 2008321 D 1112912 CDS YP_005155734.1 376281728 11727481 2009049..2009834 1 NC_016797.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2009834 hisF 11727481 hisF Brucella suis VBI22 imidazole glycerol phosphate synthase subunit HisF YP_005155734.1 2009049 D 1112912 CDS YP_005155735.1 376281729 11727482 2009970..2010293 1 NC_016797.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 2010293 hisE 11727482 hisE Brucella suis VBI22 phosphoribosyl-ATP pyrophosphatase YP_005155735.1 2009970 D 1112912 CDS YP_005155736.1 376281730 11727483 2010308..2011276 1 NC_016797.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 2011276 coaA 11727483 coaA Brucella suis VBI22 pantothenate kinase YP_005155736.1 2010308 D 1112912 CDS YP_005155737.1 376281731 11727484 complement(2011339..2011788) 1 NC_016797.1 identified by match to protein family HMM PF00472; peptidyl-tRNA hydrolase domain-containing protein 2011788 11727484 BSVBI22_A2084 Brucella suis VBI22 peptidyl-tRNA hydrolase domain-containing protein YP_005155737.1 2011339 R 1112912 CDS YP_005155738.1 376281732 11727485 complement(2011887..2013497) 1 NC_016797.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 2013497 pckA 11727485 pckA Brucella suis VBI22 phosphoenolpyruvate carboxykinase YP_005155738.1 2011887 R 1112912 CDS YP_005155739.1 376281733 11727486 2013900..2014619 1 NC_016797.1 identified by similarity to GP:2947107; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator BvrR 2014619 11727486 BSVBI22_A2086 Brucella suis VBI22 DNA-binding response regulator BvrR YP_005155739.1 2013900 D 1112912 CDS YP_005155740.1 376281734 11727487 2014730..2016535 1 NC_016797.1 identified by similarity to GP:2947211; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase BvrS 2016535 11727487 BSVBI22_A2087 Brucella suis VBI22 sensor histidine kinase BvrS YP_005155740.1 2014730 D 1112912 CDS YP_005155741.1 376281735 11727488 2016561..2017040 1 NC_016797.1 identified by similarity to GP:14024999; hypothetical protein 2017040 11727488 BSVBI22_A2088 Brucella suis VBI22 hypothetical protein YP_005155741.1 2016561 D 1112912 CDS YP_005155742.1 376281736 11727489 2017015..2017290 1 NC_016797.1 hypothetical protein 2017290 11727489 BSVBI22_A2089 Brucella suis VBI22 hypothetical protein YP_005155742.1 2017015 D 1112912 CDS YP_005155743.1 376281737 11727490 2017292..2017693 1 NC_016797.1 identified by similarity to EGAD:7066; match to protein family HMM PF03610; PTS system transporter subunit IIA 2017693 11727490 BSVBI22_A2090 Brucella suis VBI22 PTS system transporter subunit IIA YP_005155743.1 2017292 D 1112912 CDS YP_005155744.1 376281738 11727491 2017697..2018011 1 NC_016797.1 identified by similarity to SP:P08877; match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphocarrier protein HPr 2018011 ptsH 11727491 ptsH Brucella suis VBI22 phosphocarrier protein HPr YP_005155744.1 2017697 D 1112912 CDS YP_005155745.1 376281739 11727492 2018075..2018392 1 NC_016797.1 hypothetical protein 2018392 11727492 BSVBI22_A2092 Brucella suis VBI22 hypothetical protein YP_005155745.1 2018075 D 1112912 CDS YP_005155746.1 376281740 11727493 2018389..2019789 1 NC_016797.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 2019789 ahcY 11727493 ahcY Brucella suis VBI22 S-adenosyl-L-homocysteine hydrolase YP_005155746.1 2018389 D 1112912 CDS YP_005155747.1 376281741 11727494 2019977..2020186 1 NC_016797.1 hypothetical protein 2020186 11727494 BSVBI22_A2094 Brucella suis VBI22 hypothetical protein YP_005155747.1 2019977 D 1112912 CDS YP_005155748.1 376281742 11727495 2020174..2022753 1 NC_016797.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensory box histidine kinase 2022753 11727495 BSVBI22_A2095 Brucella suis VBI22 sensory box histidine kinase YP_005155748.1 2020174 D 1112912 CDS YP_005155749.1 376281743 11727496 2022762..2024303 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3919; match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein 2024303 11727496 BSVBI22_A2096 Brucella suis VBI22 hypothetical protein YP_005155749.1 2022762 D 1112912 CDS YP_005155750.1 376281744 11727497 2024290..2025009 1 NC_016797.1 identified by similarity to GP:14024993; match to protein family HMM PF00483; nucleotidyltransferase family protein 2025009 11727497 BSVBI22_A2097 Brucella suis VBI22 nucleotidyltransferase family protein YP_005155750.1 2024290 D 1112912 CDS YP_005155751.1 376281745 11727498 2025024..2028182 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3917; hypothetical protein 2028182 11727498 BSVBI22_A2098 Brucella suis VBI22 hypothetical protein YP_005155751.1 2025024 D 1112912 CDS YP_005155752.1 376281746 11727499 2028179..2031721 1 NC_016797.1 identified by similarity to OMNI:CC3538; match to protein family HMM PF00580; UvrD/Rep family helicase 2031721 11727499 BSVBI22_A2099 Brucella suis VBI22 UvrD/Rep family helicase YP_005155752.1 2028179 D 1112912 CDS YP_005155753.1 376281747 11727500 2031699..2031836 1 NC_016797.1 hypothetical protein 2031836 11727500 BSVBI22_A2100 Brucella suis VBI22 hypothetical protein YP_005155753.1 2031699 D 1112912 CDS YP_005155754.1 376281748 11727501 2031903..2032226 1 NC_016797.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 2032226 trx-1 11727501 trx-1 Brucella suis VBI22 thioredoxin YP_005155754.1 2031903 D 1112912 CDS YP_005155755.1 376281749 11727502 complement(2032440..2033768) 1 NC_016797.1 identified by match to protein family HMM TIGR01499; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 2033768 folC 11727502 folC Brucella suis VBI22 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_005155755.1 2032440 R 1112912 CDS YP_005155756.1 376281750 11727503 complement(2033771..2034676) 1 NC_016797.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 2034676 accD 11727503 accD Brucella suis VBI22 acetyl-CoA carboxylase subunit beta YP_005155756.1 2033771 R 1112912 CDS YP_005155757.1 376281751 11727504 complement(2034737..2035576) 1 NC_016797.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 2035576 trpA 11727504 trpA Brucella suis VBI22 tryptophan synthase subunit alpha YP_005155757.1 2034737 R 1112912 CDS YP_005155758.1 376281752 11727505 complement(2035573..2035920) 1 NC_016797.1 hypothetical protein 2035920 11727505 BSVBI22_A2105 Brucella suis VBI22 hypothetical protein YP_005155758.1 2035573 R 1112912 CDS YP_005155759.1 376281753 11727506 complement(2036043..2037263) 1 NC_016797.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 2037263 trpB 11727506 trpB Brucella suis VBI22 tryptophan synthase subunit beta YP_005155759.1 2036043 R 1112912 CDS YP_005155760.1 376281754 11727507 complement(2037283..2037951) 1 NC_016797.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 2037951 trpF 11727507 trpF Brucella suis VBI22 N-(5'-phosphoribosyl)anthranilate isomerase YP_005155760.1 2037283 R 1112912 CDS YP_005155761.1 376281755 11727508 complement(2037990..2038625) 1 NC_016797.1 identified by similarity to OMNI:VC1698; hypothetical protein 2038625 11727508 BSVBI22_A2108 Brucella suis VBI22 hypothetical protein YP_005155761.1 2037990 R 1112912 CDS YP_005155762.1 376281756 11727509 complement(2038622..2039383) 1 NC_016797.1 identified by similarity to GP:15154876; match to protein family HMM PF01863; hypothetical protein 2039383 11727509 BSVBI22_A2109 Brucella suis VBI22 hypothetical protein YP_005155762.1 2038622 R 1112912 CDS YP_005155763.1 376281757 11727510 complement(2039492..2039938) 1 NC_016797.1 identified by similarity to GP:15072953; hypothetical protein 2039938 11727510 BSVBI22_A2110 Brucella suis VBI22 hypothetical protein YP_005155763.1 2039492 R 1112912 CDS YP_005155764.1 376281758 11727511 complement(2040120..2041271) 1 NC_016797.1 identified by match to protein family HMM PF03594; match to protein family HMM TIGR00843; benzoate transport protein 2041271 11727511 BSVBI22_A2111 Brucella suis VBI22 benzoate transport protein YP_005155764.1 2040120 R 1112912 CDS YP_005155765.1 376281759 11727512 complement(2041285..2042076) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3900; hypothetical protein 2042076 11727512 BSVBI22_A2112 Brucella suis VBI22 hypothetical protein YP_005155765.1 2041285 R 1112912 CDS YP_005155766.1 376281760 11727513 2042508..2042912 1 NC_016797.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2042912 infC 11727513 infC Brucella suis VBI22 translation initiation factor IF-3 YP_005155766.1 2042508 D 1112912 CDS YP_005155767.1 376281761 11727514 2043041..2043655 1 NC_016797.1 identified by similarity to EGAD:42737; nickel-cobalt-cadmium resistance protein 2043655 11727514 BSVBI22_A2114 Brucella suis VBI22 nickel-cobalt-cadmium resistance protein YP_005155767.1 2043041 D 1112912 CDS YP_005155768.1 376281762 11727515 2043922..2044122 1 NC_016797.1 identified by similarity to SP:P55874; match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 2044122 rpmI 11727515 rpmI Brucella suis VBI22 50S ribosomal protein L35 YP_005155768.1 2043922 D 1112912 CDS YP_005155769.1 376281763 11727516 2044150..2044554 1 NC_016797.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2044554 rplT 11727516 rplT Brucella suis VBI22 50S ribosomal protein L20 YP_005155769.1 2044150 D 1112912 CDS YP_005155770.1 376281764 11727517 2044653..2045495 1 NC_016797.1 identified by similarity to GP:15155150; hypothetical protein 2045495 11727517 BSVBI22_A2117 Brucella suis VBI22 hypothetical protein YP_005155770.1 2044653 D 1112912 CDS YP_005155771.1 376281765 11727518 2045584..2046693 1 NC_016797.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2046693 pheS 11727518 pheS Brucella suis VBI22 phenylalanyl-tRNA synthetase subunit alpha YP_005155771.1 2045584 D 1112912 CDS YP_005155772.1 376281766 11727519 2046715..2049129 1 NC_016797.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2049129 pheT 11727519 pheT Brucella suis VBI22 phenylalanyl-tRNA synthetase subunit beta YP_005155772.1 2046715 D 1112912 CDS YP_005155773.1 376281767 11727520 2049199..2050185 1 NC_016797.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 2050185 11727520 BSVBI22_A2120 Brucella suis VBI22 Gfo/Idh/MocA family oxidoreductase YP_005155773.1 2049199 D 1112912 CDS YP_005155774.1 376281768 11727521 2050411..2052324 1 NC_016797.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 2052324 dnaK 11727521 dnaK Brucella suis VBI22 molecular chaperone DnaK YP_005155774.1 2050411 D 1112912 CDS YP_005155775.1 376281769 11727522 2052569..2053702 1 NC_016797.1 identified by similarity to EGAD:7249; match to protein family HMM PF00226; match to protein family HMM PF00684; match to protein family HMM PF01556; chaperone protein DnaJ 2053702 dnaJ 11727522 dnaJ Brucella suis VBI22 chaperone protein DnaJ YP_005155775.1 2052569 D 1112912 CDS YP_005155776.1 376281770 11727523 2053823..2054422 1 NC_016797.1 identified by similarity to GP:9966391; phospholipid N-methyltransferase 2054422 pmtA 11727523 pmtA Brucella suis VBI22 phospholipid N-methyltransferase YP_005155776.1 2053823 D 1112912 CDS YP_005155777.1 376281771 11727524 2054632..2055348 1 NC_016797.1 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2055348 pyrF 11727524 pyrF Brucella suis VBI22 orotidine 5'-phosphate decarboxylase YP_005155777.1 2054632 D 1112912 CDS YP_005155778.1 376281772 11727525 2055397..2055684 1 NC_016797.1 identified by similarity to GP:15155195; hypothetical protein 2055684 11727525 BSVBI22_A2125 Brucella suis VBI22 hypothetical protein YP_005155778.1 2055397 D 1112912 CDS YP_005155779.1 376281773 11727526 complement(2055722..2056909) 1 NC_016797.1 identified by similarity to OMNI:NTL02ML3653; match to protein family HMM PF03758; Smp-30/Cgr1 family protein, putative 2056909 11727526 BSVBI22_A2126 Brucella suis VBI22 Smp-30/Cgr1 family protein, putative YP_005155779.1 2055722 R 1112912 CDS YP_005155780.1 376281774 11727527 2056845..2057783 1 NC_016797.1 The second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 2057783 gshb 11727527 gshb Brucella suis VBI22 glutathione synthetase YP_005155780.1 2056845 D 1112912 CDS YP_005155781.1 376281775 11727528 2057893..2059425 1 NC_016797.1 identified by match to protein family HMM PF01078; match to protein family HMM TIGR00368; Mg chelatase-like protein 2059425 11727528 BSVBI22_A2128 Brucella suis VBI22 Mg chelatase-like protein YP_005155781.1 2057893 D 1112912 CDS YP_005155782.1 376281776 11727529 complement(2059474..2060094) 1 NC_016797.1 identified by similarity to GP:15074346; hypothetical protein 2060094 11727529 BSVBI22_A2129 Brucella suis VBI22 hypothetical protein YP_005155782.1 2059474 R 1112912 CDS YP_005155783.1 376281777 11727530 2060355..2060468 1 NC_016797.1 hypothetical protein 2060468 11727530 BSVBI22_A2130 Brucella suis VBI22 hypothetical protein YP_005155783.1 2060355 D 1112912 CDS YP_005155784.1 376281778 11727531 complement(2060541..2060897) 1 NC_016797.1 identified by match to protein family HMM PF03330; match to protein family HMM TIGR00413; rare lipoprotein A family protein 2060897 11727531 BSVBI22_A2131 Brucella suis VBI22 rare lipoprotein A family protein YP_005155784.1 2060541 R 1112912 CDS YP_005155785.1 376281779 11727532 2061053..2061274 1 NC_016797.1 hypothetical protein 2061274 11727532 BSVBI22_A2132 Brucella suis VBI22 hypothetical protein YP_005155785.1 2061053 D 1112912 CDS YP_005155786.1 376281780 11727533 2061507..2061857 1 NC_016797.1 identified by similarity to EGAD:35582; hypothetical protein 2061857 11727533 BSVBI22_A2133 Brucella suis VBI22 hypothetical protein YP_005155786.1 2061507 D 1112912 CDS YP_005155787.1 376281781 11727534 2062012..2063058 1 NC_016797.1 phosphate ABC transporter substrate-binding protein 2063058 11727534 BSVBI22_A2134 Brucella suis VBI22 phosphate ABC transporter substrate-binding protein YP_005155787.1 2062012 D 1112912 CDS YP_005155788.1 376281782 11727535 2063200..2064690 1 NC_016797.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 2064690 pstC 11727535 pstC Brucella suis VBI22 phosphate ABC transporter permease YP_005155788.1 2063200 D 1112912 CDS YP_005155789.1 376281783 11727536 2064690..2066000 1 NC_016797.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 2066000 11727536 BSVBI22_A2136 Brucella suis VBI22 phosphate ABC transporter permease YP_005155789.1 2064690 D 1112912 CDS YP_005155790.1 376281784 11727537 2066065..2066838 1 NC_016797.1 identified by similarity to GP:6531665; match to protein family HMM PF00005; match to protein family HMM TIGR00972; phosphate ABC transporter ATP-binding protein 2066838 pstB 11727537 pstB Brucella suis VBI22 phosphate ABC transporter ATP-binding protein YP_005155790.1 2066065 D 1112912 CDS YP_005155791.1 376281785 11727538 2066904..2067626 1 NC_016797.1 identified by similarity to EGAD:14202; match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 2067626 phoU 11727538 phoU Brucella suis VBI22 phosphate transport system regulatory protein PhoU YP_005155791.1 2066904 D 1112912 CDS YP_005155792.1 376281786 11727539 2067744..2068430 1 NC_016797.1 identified by similarity to EGAD:5895; match to protein family HMM PF00072; match to protein family HMM PF00486; match to protein family HMM TIGR02154; phosphate regulon transcriptional regulatory protein Phob 2068430 phoB 11727539 phoB Brucella suis VBI22 phosphate regulon transcriptional regulatory protein Phob YP_005155792.1 2067744 D 1112912 CDS YP_005155793.1 376281787 11727540 complement(2068786..2068944) 1 NC_016797.1 hypothetical protein 2068944 11727540 BSVBI22_A2140 Brucella suis VBI22 hypothetical protein YP_005155793.1 2068786 R 1112912 CDS YP_005155794.1 376281788 11727541 2069016..2069996 1 NC_016797.1 identified by similarity to OMNI:NTL02ML4270; putative lipoprotein 2069996 11727541 BSVBI22_A2141 Brucella suis VBI22 putative lipoprotein YP_005155794.1 2069016 D 1112912 CDS YP_005155795.1 376281789 11727542 complement(2070106..2070429) 1 NC_016797.1 identified by similarity to GP:15155785; putative lipoprotein 2070429 11727542 BSVBI22_A2142 Brucella suis VBI22 putative lipoprotein YP_005155795.1 2070106 R 1112912 CDS YP_005155796.1 376281790 11727543 complement(2070419..2070523) 1 NC_016797.1 hypothetical protein 2070523 11727543 BSVBI22_A2143 Brucella suis VBI22 hypothetical protein YP_005155796.1 2070419 R 1112912 CDS YP_005155797.1 376281791 11727544 2070506..2071759 1 NC_016797.1 identified by similarity to SP:Q9X4A7; match to protein family HMM PF02073; aminopeptidase PepS 2071759 pepS 11727544 pepS Brucella suis VBI22 aminopeptidase PepS YP_005155797.1 2070506 D 1112912 CDS YP_005155798.1 376281792 11727545 complement(2071920..2072417) 1 NC_016797.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 2072417 11727545 BSVBI22_A2145 Brucella suis VBI22 DNA starvation/stationary phase protection protein Dps YP_005155798.1 2071920 R 1112912 CDS YP_005155799.1 376281793 11727546 2072604..2073389 1 NC_016797.1 identified by match to protein family HMM PF00814; protease 2073389 11727546 BSVBI22_A2146 Brucella suis VBI22 protease YP_005155799.1 2072604 D 1112912 CDS YP_005155800.1 376281794 11727547 2073394..2073894 1 NC_016797.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575; acetyltransferase 2073894 11727547 BSVBI22_A2147 Brucella suis VBI22 acetyltransferase YP_005155800.1 2073394 D 1112912 CDS YP_005155801.1 376281795 11727548 2073891..2074694 1 NC_016797.1 identified by match to protein family HMM PF01553; acyltransferase 2074694 11727548 BSVBI22_A2148 Brucella suis VBI22 acyltransferase YP_005155801.1 2073891 D 1112912 CDS YP_005155802.1 376281796 11727549 2074752..2076155 1 NC_016797.1 identified by similarity to GP:14025368; match to protein family HMM PF00919; match to protein family HMM PF01938; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01574; hypothetical protein 2076155 11727549 BSVBI22_A2149 Brucella suis VBI22 hypothetical protein YP_005155802.1 2074752 D 1112912 CDS YP_005155803.1 376281797 11727550 complement(2076253..2076345) 1 NC_016797.1 hypothetical protein 2076345 11727550 BSVBI22_A2150 Brucella suis VBI22 hypothetical protein YP_005155803.1 2076253 R 1112912 CDS YP_005155804.1 376281798 11727551 2076392..2077375 1 NC_016797.1 identified by match to protein family HMM PF02562; PhoH family protein 2077375 11727551 BSVBI22_A2151 Brucella suis VBI22 PhoH family protein YP_005155804.1 2076392 D 1112912 CDS YP_005155805.1 376281799 11727552 2077541..2078017 1 NC_016797.1 identified by similarity to OMNI:NTL02ML4294; match to protein family HMM PF02130; match to protein family HMM TIGR00043; hypothetical protein 2078017 11727552 BSVBI22_A2152 Brucella suis VBI22 hypothetical protein YP_005155805.1 2077541 D 1112912 CDS YP_005155806.1 376281800 11727553 2078110..2079138 1 NC_016797.1 identified by similarity to OMNI:VC0959; match to protein family HMM PF00571; match to protein family HMM PF03471; hypothetical protein 2079138 11727553 BSVBI22_A2153 Brucella suis VBI22 hypothetical protein YP_005155806.1 2078110 D 1112912 CDS YP_005155807.1 376281801 11727554 2079135..2080733 1 NC_016797.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 2080733 lnt 11727554 lnt Brucella suis VBI22 apolipoprotein N-acyltransferase YP_005155807.1 2079135 D 1112912 CDS YP_005155808.1 376281802 11727555 2080880..2081293 1 NC_016797.1 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 2081293 11727555 BSVBI22_A2155 Brucella suis VBI22 Cro/CI family transcriptional regulator YP_005155808.1 2080880 D 1112912 CDS YP_005155809.1 376281803 11727556 2081520..2082785 1 NC_016797.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2082785 metK 11727556 metK Brucella suis VBI22 S-adenosylmethionine synthetase YP_005155809.1 2081520 D 1112912 CDS YP_005155810.1 376281804 11727557 2082794..2083495 1 NC_016797.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 2083495 trmB 11727557 trmB Brucella suis VBI22 tRNA (guanine-N(7)-)-methyltransferase YP_005155810.1 2082794 D 1112912 CDS YP_005155811.1 376281805 11727558 2083675..2084334 1 NC_016797.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 2084334 11727558 BSVBI22_A2158 Brucella suis VBI22 hypothetical protein YP_005155811.1 2083675 D 1112912 CDS YP_005155812.1 376281806 11727559 2084387..2086000 1 NC_016797.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 2086000 nusA 11727559 nusA Brucella suis VBI22 transcription elongation factor NusA YP_005155812.1 2084387 D 1112912 CDS YP_005155813.1 376281807 11727560 2086382..2086984 1 NC_016797.1 identified by similarity to GP:15073167; match to protein family HMM PF04296; hypothetical protein 2086984 11727560 BSVBI22_A2160 Brucella suis VBI22 hypothetical protein YP_005155813.1 2086382 D 1112912 CDS YP_005155814.1 376281808 11727561 2087122..2090001 1 NC_016797.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 2090001 infB 11727561 infB Brucella suis VBI22 translation initiation factor IF-2 YP_005155814.1 2087122 D 1112912 CDS YP_005155815.1 376281809 11727562 2090267..2090719 1 NC_016797.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 2090719 rbfA 11727562 rbfA Brucella suis VBI22 ribosome-binding factor A YP_005155815.1 2090267 D 1112912 CDS YP_005155816.1 376281810 11727563 2090723..2091697 1 NC_016797.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 2091697 truB 11727563 truB Brucella suis VBI22 tRNA pseudouridine synthase B YP_005155816.1 2090723 D 1112912 CDS YP_005155817.1 376281811 11727564 2091868..2092137 1 NC_016797.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 2092137 rpsO 11727564 rpsO Brucella suis VBI22 30S ribosomal protein S15 YP_005155817.1 2091868 D 1112912 CDS YP_005155818.1 376281812 11727565 2092421..2094565 1 NC_016797.1 identified by similarity to SP:P05055; match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; polynucleotide phosphorylase/polyadenylase 2094565 pnp 11727565 pnp Brucella suis VBI22 polynucleotide phosphorylase/polyadenylase YP_005155818.1 2092421 D 1112912 CDS YP_005155819.1 376281813 11727566 2094676..2095698 1 NC_016797.1 identified by match to protein family HMM PF05175; methyltransferase 2095698 11727566 BSVBI22_A2166 Brucella suis VBI22 methyltransferase YP_005155819.1 2094676 D 1112912 CDS YP_005155820.1 376281814 11727567 complement(2095746..2096564) 1 NC_016797.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 2096564 fabI-2 11727567 fabI-2 Brucella suis VBI22 enoyl-ACP reductase YP_005155820.1 2095746 R 1112912 CDS YP_005155821.1 376281815 11727568 complement(2096579..2097802) 1 NC_016797.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2097802 fabB 11727568 fabB Brucella suis VBI22 3-oxoacyl-ACP synthase YP_005155821.1 2096579 R 1112912 CDS YP_005155822.1 376281816 11727569 complement(2097968..2098486) 1 NC_016797.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 2098486 fabA 11727569 fabA Brucella suis VBI22 3-hydroxydecanoyl-ACP dehydratase YP_005155822.1 2097968 R 1112912 CDS YP_005155823.1 376281817 11727570 2098733..2099176 1 NC_016797.1 identified by match to protein family HMM PF01475; ferric uptake regulator family protein 2099176 11727570 BSVBI22_A2170 Brucella suis VBI22 ferric uptake regulator family protein YP_005155823.1 2098733 D 1112912 CDS YP_005155824.1 376281818 11727571 2099342..2100121 1 NC_016797.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363; YaeC family lipoprotein 2100121 11727571 BSVBI22_A2171 Brucella suis VBI22 YaeC family lipoprotein YP_005155824.1 2099342 D 1112912 CDS YP_005155825.1 376281819 11727572 complement(2100166..2100711) 1 NC_016797.1 identified by similarity to GP:14025396; hypothetical protein 2100711 11727572 BSVBI22_A2172 Brucella suis VBI22 hypothetical protein YP_005155825.1 2100166 R 1112912 CDS YP_005155826.1 376281820 11727573 2101062..2102066 1 NC_016797.1 Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 2102066 11727573 BSVBI22_A2173 Brucella suis VBI22 2-hydroxyacid dehydrogenase YP_005155826.1 2101062 D 1112912 CDS YP_005155827.1 376281821 11727574 complement(2102091..2102792) 1 NC_016797.1 hydrolase 2102792 11727574 BSVBI22_A2174 Brucella suis VBI22 hydrolase YP_005155827.1 2102091 R 1112912 CDS YP_005155828.1 376281822 11727575 complement(2102814..2103686) 1 NC_016797.1 identified by match to protein family HMM PF00877; NLP/P60 family protein 2103686 11727575 BSVBI22_A2175 Brucella suis VBI22 NLP/P60 family protein YP_005155828.1 2102814 R 1112912 CDS YP_005155829.1 376281823 11727576 complement(2103683..2104033) 1 NC_016797.1 identified by similarity to GP:15073078; transcriptional regulator 2104033 11727576 BSVBI22_A2176 Brucella suis VBI22 transcriptional regulator YP_005155829.1 2103683 R 1112912 CDS YP_005155830.1 376281824 11727577 complement(2104108..2105490) 1 NC_016797.1 identified by match to protein family HMM PF00883; cytosol aminopeptidase 2105490 11727577 BSVBI22_A2177 Brucella suis VBI22 cytosol aminopeptidase YP_005155830.1 2104108 R 1112912 CDS YP_005155831.1 376281825 11727578 complement(2105650..2105829) 1 NC_016797.1 identified by similarity to OMNI:CC2948; pilus biosynthesis protein-related protein 2105829 11727578 BSVBI22_A2178 Brucella suis VBI22 pilus biosynthesis protein-related protein YP_005155831.1 2105650 R 1112912 CDS YP_005155832.1 376281826 11727579 2106049..2106930 1 NC_016797.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 2106930 mutM 11727579 mutM Brucella suis VBI22 formamidopyrimidine-DNA glycosylase YP_005155832.1 2106049 D 1112912 CDS YP_005155833.1 376281827 11727580 2107057..2107830 1 NC_016797.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2107830 11727580 BSVBI22_A2180 Brucella suis VBI22 enoyl-CoA hydratase YP_005155833.1 2107057 D 1112912 CDS YP_005155834.1 376281828 11727581 2108166..2108432 1 NC_016797.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 2108432 rpsT 11727581 rpsT Brucella suis VBI22 30S ribosomal protein S20 YP_005155834.1 2108166 D 1112912 CDS