-- dump date 20140619_005318 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_007233626.1 431806728 14294490 24..1382 1 NC_019908.1 COG0593 ATPase involved in DNA replication initiation; chromosomal replication initiation protein 1382 14294490 BPP43_00005 Brachyspira pilosicoli P43/6/78 chromosomal replication initiation protein YP_007233626.1 24 D 1042417 CDS YP_007233627.1 431806729 14294495 1852..2493 1 NC_019908.1 COG0576 Molecular chaperone GrpE (heat shock protein); protein grpE HSP 70 cofactor 2493 14294495 BPP43_00010 Brachyspira pilosicoli P43/6/78 protein grpE HSP 70 cofactor YP_007233627.1 1852 D 1042417 CDS YP_007233628.1 431806730 14294496 2517..2726 1 NC_019908.1 hypothetical protein 2726 14294496 BPP43_00015 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233628.1 2517 D 1042417 CDS YP_007233629.1 431806731 14294497 2784..4703 1 NC_019908.1 COG0443 Molecular chaperone; molecular chaperone DnaK 4703 14294497 BPP43_00020 Brachyspira pilosicoli P43/6/78 molecular chaperone DnaK YP_007233629.1 2784 D 1042417 CDS YP_007233630.1 431806732 14294498 5082..5966 1 NC_019908.1 hypothetical protein 5966 14294498 BPP43_00025 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233630.1 5082 D 1042417 CDS YP_007233631.1 431806733 14294499 5994..6344 1 NC_019908.1 COG0073 EMAP domain; methionine-tRNA ligase 6344 14294499 BPP43_00030 Brachyspira pilosicoli P43/6/78 methionine-tRNA ligase YP_007233631.1 5994 D 1042417 CDS YP_007233632.1 431806734 14294500 6440..7294 1 NC_019908.1 COG0714 MoxR-like ATPases; ATPase 7294 14294500 BPP43_00035 Brachyspira pilosicoli P43/6/78 ATPase YP_007233632.1 6440 D 1042417 CDS YP_007233633.1 431806735 14294501 7287..7976 1 NC_019908.1 COG0352 Thiamine monophosphate synthase; thiamine-phosphate pyrophosphorylase 7976 14294501 BPP43_00040 Brachyspira pilosicoli P43/6/78 thiamine-phosphate pyrophosphorylase YP_007233633.1 7287 D 1042417 CDS YP_007233634.1 431806736 14294502 8429..8806 1 NC_019908.1 COG1525 Micrococcal nuclease (thermonuclease) homologs; thermonuclease family protein 8806 14294502 BPP43_00045 Brachyspira pilosicoli P43/6/78 thermonuclease family protein YP_007233634.1 8429 D 1042417 CDS YP_007233635.1 431806737 14294503 11470..12165 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 12165 14294503 BPP43_00060 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233635.1 11470 D 1042417 CDS YP_007233636.1 431806738 14294504 12193..13890 1 NC_019908.1 COG1061 DNA or RNA helicases of superfamily II; DNA repair helicase 13890 14294504 BPP43_00065 Brachyspira pilosicoli P43/6/78 DNA repair helicase YP_007233636.1 12193 D 1042417 CDS YP_007233637.1 431806739 14294505 complement(14198..15037) 1 NC_019908.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 15037 14294505 BPP43_00070 Brachyspira pilosicoli P43/6/78 glycosyltransferase YP_007233637.1 14198 R 1042417 CDS YP_007233638.1 431806740 14294506 complement(15366..15923) 1 NC_019908.1 transmembrane protein 15923 14294506 BPP43_00075 Brachyspira pilosicoli P43/6/78 transmembrane protein YP_007233638.1 15366 R 1042417 CDS YP_007233639.1 431806741 14294507 16060..17892 1 NC_019908.1 COG0750 Predicted membrane-associated Zn-dependent proteases 1; hypothetical protein 17892 14294507 BPP43_00080 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233639.1 16060 D 1042417 CDS YP_007233640.1 431806742 14294508 17879..19930 1 NC_019908.1 YD repeat-containing protein 19930 14294508 BPP43_00085 Brachyspira pilosicoli P43/6/78 YD repeat-containing protein YP_007233640.1 17879 D 1042417 CDS YP_007233641.1 431806743 14294509 19947..20138 1 NC_019908.1 hypothetical protein 20138 14294509 BPP43_00090 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233641.1 19947 D 1042417 CDS YP_007233642.1 431806744 14294510 20233..20547 1 NC_019908.1 hypothetical protein 20547 14294510 BPP43_00095 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233642.1 20233 D 1042417 CDS YP_007233643.1 431806745 14294511 20668..21039 1 NC_019908.1 hypothetical protein 21039 14294511 BPP43_00100 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233643.1 20668 D 1042417 CDS YP_007233644.1 431806746 14294512 21230..21934 1 NC_019908.1 COG0528 Uridylate kinase; aspartate/glutamate/uridylate kinase 21934 14294512 BPP43_00105 Brachyspira pilosicoli P43/6/78 aspartate/glutamate/uridylate kinase YP_007233644.1 21230 D 1042417 CDS YP_007233645.1 431806747 14294513 21970..22971 1 NC_019908.1 COG4864 Uncharacterized protein conserved in bacteria; hypothetical protein 22971 14294513 BPP43_00110 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233645.1 21970 D 1042417 CDS YP_007233646.1 431806748 14294514 23046..23660 1 NC_019908.1 COG1061 DNA or RNA helicases of superfamily II; metal-dependent phosphohydrolase 23660 14294514 BPP43_00115 Brachyspira pilosicoli P43/6/78 metal-dependent phosphohydrolase YP_007233646.1 23046 D 1042417 CDS YP_007233647.1 431806749 14294515 23703..24683 1 NC_019908.1 COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; histidinol-phosphate aminotransferase 24683 14294515 BPP43_00120 Brachyspira pilosicoli P43/6/78 histidinol-phosphate aminotransferase YP_007233647.1 23703 D 1042417 CDS YP_007233648.1 431806750 14294516 complement(24676..25557) 1 NC_019908.1 COG0224 F0F1-type ATP synthase, gamma subunit; ATP synthase subunit gamma 25557 14294516 BPP43_00125 Brachyspira pilosicoli P43/6/78 ATP synthase subunit gamma YP_007233648.1 24676 R 1042417 CDS YP_007233649.1 431806751 14294517 complement(25559..26404) 1 NC_019908.1 D-alpha,beta-D-heptose-1,7-biphosphate phosphatase GmhB 26404 14294517 BPP43_00130 Brachyspira pilosicoli P43/6/78 D-alpha,beta-D-heptose-1,7-biphosphate phosphatase GmhB YP_007233649.1 25559 R 1042417 CDS YP_007233650.1 431806752 14294518 complement(26397..27230) 1 NC_019908.1 glycosyltransferase family 14 protein 27230 14294518 BPP43_00135 Brachyspira pilosicoli P43/6/78 glycosyltransferase family 14 protein YP_007233650.1 26397 R 1042417 CDS YP_007233651.1 431806753 14294519 complement(27233..28732) 1 NC_019908.1 COG0056 F0F1-type ATP synthase, alpha subunit; F0F1 ATP synthase subunit alpha 28732 14294519 BPP43_00140 Brachyspira pilosicoli P43/6/78 F0F1 ATP synthase subunit alpha YP_007233651.1 27233 R 1042417 CDS YP_007233652.1 431806754 14294520 complement(28764..29390) 1 NC_019908.1 COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein); F0F1 ATP synthase subunit delta 29390 14294520 BPP43_00145 Brachyspira pilosicoli P43/6/78 F0F1 ATP synthase subunit delta YP_007233652.1 28764 R 1042417 CDS YP_007233653.1 431806755 14294521 complement(29416..29952) 1 NC_019908.1 COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein); F0F1 ATP synthase subunit delta 29952 14294521 BPP43_00150 Brachyspira pilosicoli P43/6/78 F0F1 ATP synthase subunit delta YP_007233653.1 29416 R 1042417 CDS YP_007233654.1 431806756 14294522 complement(29992..30492) 1 NC_019908.1 COG0711 F0F1-type ATP synthase, subunit b; F0F1 type ATP synthase subunit B 30492 14294522 BPP43_00155 Brachyspira pilosicoli P43/6/78 F0F1 type ATP synthase subunit B YP_007233654.1 29992 R 1042417 CDS YP_007233655.1 431806757 14294523 complement(30541..30762) 1 NC_019908.1 COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K; ATP synthase subunit C 30762 14294523 BPP43_00160 Brachyspira pilosicoli P43/6/78 ATP synthase subunit C YP_007233655.1 30541 R 1042417 CDS YP_007233656.1 431806758 14294524 complement(30805..31713) 1 NC_019908.1 COG0356 F0F1-type ATP synthase, subunit a; F0 ATP synthase subunit A 31713 14294524 BPP43_00165 Brachyspira pilosicoli P43/6/78 F0 ATP synthase subunit A YP_007233656.1 30805 R 1042417 CDS YP_007233657.1 431806759 14294525 complement(31781..32116) 1 NC_019908.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); anti sigma factor antagonist 32116 14294525 BPP43_00170 Brachyspira pilosicoli P43/6/78 anti sigma factor antagonist YP_007233657.1 31781 R 1042417 CDS YP_007233658.1 431806760 14294526 complement(32273..33817) 1 NC_019908.1 COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; 5'-nucleotidase 33817 14294526 BPP43_00175 Brachyspira pilosicoli P43/6/78 5'-nucleotidase YP_007233658.1 32273 R 1042417 CDS YP_007233659.1 431806761 14294527 complement(33881..35425) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 35425 14294527 BPP43_00180 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233659.1 33881 R 1042417 CDS YP_007233660.1 431806762 14294528 complement(35542..35772) 1 NC_019908.1 hypothetical protein 35772 14294528 BPP43_00185 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233660.1 35542 R 1042417 CDS YP_007233661.1 431806763 14294529 36539..39304 1 NC_019908.1 COG0060 Isoleucyl-tRNA synthetase; isoleucyl-tRNA-synthetase 39304 14294529 BPP43_00200 Brachyspira pilosicoli P43/6/78 isoleucyl-tRNA-synthetase YP_007233661.1 36539 D 1042417 CDS YP_007233662.1 431806764 14294530 39479..39751 1 NC_019908.1 hypothetical protein 39751 14294530 BPP43_00205 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233662.1 39479 D 1042417 CDS YP_007233663.1 431806765 14294531 40032..40364 1 NC_019908.1 COG1695 Predicted transcriptional regulators; hypothetical protein 40364 14294531 BPP43_00210 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233663.1 40032 D 1042417 CDS YP_007233664.1 431806766 14294532 40384..41349 1 NC_019908.1 COG3839 ABC-type sugar transport systems, ATPase components; hypothetical protein 41349 14294532 BPP43_00215 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233664.1 40384 D 1042417 CDS YP_007233665.1 431806767 14294533 41493..44531 1 NC_019908.1 COG1002 Type II restriction enzyme, methylase subunits; bifunctional endonuclease/methyltransferase 44531 14294533 BPP43_00220 Brachyspira pilosicoli P43/6/78 bifunctional endonuclease/methyltransferase YP_007233665.1 41493 D 1042417 CDS YP_007233666.1 431806768 14294534 44531..46162 1 NC_019908.1 COG3344 Retron-type reverse transcriptase; hypothetical protein 46162 14294534 BPP43_00225 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233666.1 44531 D 1042417 CDS YP_007233667.1 431806769 14294535 46083..46274 1 NC_019908.1 hypothetical protein 46274 14294535 BPP43_00230 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233667.1 46083 D 1042417 CDS YP_007233668.1 431806770 14294536 46685..47959 1 NC_019908.1 COG0366 Glycosidases; alpha amylase 47959 14294536 BPP43_00235 Brachyspira pilosicoli P43/6/78 alpha amylase YP_007233668.1 46685 D 1042417 CDS YP_007233669.1 431806771 14294537 47966..50365 1 NC_019908.1 COG0642 Signal transduction histidine kinase; GAF sensor signal transduction histidine kinase 50365 14294537 BPP43_00240 Brachyspira pilosicoli P43/6/78 GAF sensor signal transduction histidine kinase YP_007233669.1 47966 D 1042417 CDS YP_007233670.1 431806772 14294538 50401..51207 1 NC_019908.1 hypothetical protein 51207 14294538 BPP43_00245 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233670.1 50401 D 1042417 CDS YP_007233671.1 431806773 14294539 52133..52249 1 NC_019908.1 hypothetical protein 52249 14294539 BPP43_00255 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233671.1 52133 D 1042417 CDS YP_007233672.1 431806774 14294540 52656..54452 1 NC_019908.1 COG0206 Cell division GTPase; cell division protein FtsZ 54452 14294540 BPP43_00265 Brachyspira pilosicoli P43/6/78 cell division protein FtsZ YP_007233672.1 52656 D 1042417 CDS YP_007233673.1 431806775 14294541 54466..56361 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 56361 14294541 BPP43_00270 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233673.1 54466 D 1042417 CDS YP_007233674.1 431806776 14294542 56371..56988 1 NC_019908.1 COG0237 Dephospho-CoA kinase; dephospho-CoA kinase 56988 14294542 BPP43_00275 Brachyspira pilosicoli P43/6/78 dephospho-CoA kinase YP_007233674.1 56371 D 1042417 CDS YP_007233675.1 431806777 14294543 56939..57802 1 NC_019908.1 sporulation-like repeat-containing protein 57802 14294543 BPP43_00280 Brachyspira pilosicoli P43/6/78 sporulation-like repeat-containing protein YP_007233675.1 56939 D 1042417 CDS YP_007233676.1 431806778 14294544 complement(57888..58775) 1 NC_019908.1 COG1533 DNA repair photolyase; radical SAM protein 58775 14294544 BPP43_00285 Brachyspira pilosicoli P43/6/78 radical SAM protein YP_007233676.1 57888 R 1042417 CDS YP_007233677.1 431806779 14294545 58920..61073 1 NC_019908.1 COG0439 Biotin carboxylase; L-lactate dehydrogenase 61073 14294545 BPP43_00290 Brachyspira pilosicoli P43/6/78 L-lactate dehydrogenase YP_007233677.1 58920 D 1042417 CDS YP_007233678.1 431806780 14294546 61084..62109 1 NC_019908.1 hypothetical protein 62109 14294546 BPP43_00295 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233678.1 61084 D 1042417 CDS YP_007233679.1 431806781 14294547 62112..63473 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 63473 14294547 BPP43_00300 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233679.1 62112 D 1042417 CDS YP_007233680.1 431806782 14294548 63575..64753 1 NC_019908.1 dynein heavy chain 64753 14294548 BPP43_00305 Brachyspira pilosicoli P43/6/78 dynein heavy chain YP_007233680.1 63575 D 1042417 CDS YP_007233681.1 431806783 14294549 64852..65160 1 NC_019908.1 hypothetical protein 65160 14294549 BPP43_00310 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233681.1 64852 D 1042417 CDS YP_007233682.1 431806784 14294550 65173..65610 1 NC_019908.1 COG0457 FOG: TPR repeat; response regulator aspartate phosphatase 65610 14294550 BPP43_00315 Brachyspira pilosicoli P43/6/78 response regulator aspartate phosphatase YP_007233682.1 65173 D 1042417 CDS YP_007233683.1 431806785 14294551 65610..67331 1 NC_019908.1 hypothetical protein 67331 14294551 BPP43_00320 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233683.1 65610 D 1042417 CDS YP_007233684.1 431806786 14294552 67321..68172 1 NC_019908.1 COG0030 Dimethyladenosine transferase (rRNA methylation); dimethyladenosine transferase 68172 14294552 BPP43_00325 Brachyspira pilosicoli P43/6/78 dimethyladenosine transferase YP_007233684.1 67321 D 1042417 CDS YP_007233685.1 431806787 14294553 complement(68169..68693) 1 NC_019908.1 hypothetical protein 68693 14294553 BPP43_00330 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233685.1 68169 R 1042417 CDS YP_007233686.1 431806788 14294554 68813..70246 1 NC_019908.1 COG0469 Pyruvate kinase; pyruvate kinase 70246 14294554 BPP43_00335 Brachyspira pilosicoli P43/6/78 pyruvate kinase YP_007233686.1 68813 D 1042417 CDS YP_007233687.1 431806789 14294555 70398..71147 1 NC_019908.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-ketoacyl-ACP reductase 71147 14294555 BPP43_00340 Brachyspira pilosicoli P43/6/78 3-ketoacyl-ACP reductase YP_007233687.1 70398 D 1042417 CDS YP_007233688.1 431806790 14294556 71219..71455 1 NC_019908.1 COG0236 Acyl carrier protein; acyl-carrier protein 71455 14294556 BPP43_00345 Brachyspira pilosicoli P43/6/78 acyl-carrier protein YP_007233688.1 71219 D 1042417 CDS YP_007233689.1 431806791 14294557 71529..72782 1 NC_019908.1 COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; ACP synthase II 72782 14294557 BPP43_00350 Brachyspira pilosicoli P43/6/78 ACP synthase II YP_007233689.1 71529 D 1042417 CDS YP_007233690.1 431806792 14294558 complement(73800..74285) 1 NC_019908.1 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase 74285 14294558 BPP43_00355 Brachyspira pilosicoli P43/6/78 peptidyl-prolyl cis-trans isomerase YP_007233690.1 73800 R 1042417 CDS YP_007233691.1 431806793 14294559 complement(74303..74869) 1 NC_019908.1 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase 74869 14294559 BPP43_00360 Brachyspira pilosicoli P43/6/78 peptidyl-prolyl cis-trans isomerase YP_007233691.1 74303 R 1042417 CDS YP_007233692.1 431806794 14294560 complement(74899..76032) 1 NC_019908.1 COG1652 Uncharacterized protein containing LysM domain; TmpB family outer membrane protein 76032 14294560 BPP43_00365 Brachyspira pilosicoli P43/6/78 TmpB family outer membrane protein YP_007233692.1 74899 R 1042417 CDS YP_007233693.1 431806795 14294561 complement(76047..76634) 1 NC_019908.1 lipoprotein 76634 14294561 BPP43_00370 Brachyspira pilosicoli P43/6/78 lipoprotein YP_007233693.1 76047 R 1042417 CDS YP_007233694.1 431806796 14294562 complement(76794..77003) 1 NC_019908.1 COG0828 Ribosomal protein S21; 30S ribosomal protein S21 77003 14294562 BPP43_00375 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S21 YP_007233694.1 76794 R 1042417 CDS YP_007233695.1 431806797 14294565 77408..77956 1 NC_019908.1 COG0233 Ribosome recycling factor; Ribosome recycling factor 77956 14294565 BPP43_00380 Brachyspira pilosicoli P43/6/78 Ribosome recycling factor YP_007233695.1 77408 D 1042417 CDS YP_007233696.1 431806798 14294566 77959..78684 1 NC_019908.1 COG0020 Undecaprenyl pyrophosphate synthase; undecaprenyl pyrophosphate synthetase 78684 14294566 BPP43_00385 Brachyspira pilosicoli P43/6/78 undecaprenyl pyrophosphate synthetase YP_007233696.1 77959 D 1042417 CDS YP_007233697.1 431806799 14294567 78688..79596 1 NC_019908.1 COG0575 CDP-diglyceride synthetase; phosphatidate cytidylyltransferase 79596 14294567 BPP43_00390 Brachyspira pilosicoli P43/6/78 phosphatidate cytidylyltransferase YP_007233697.1 78688 D 1042417 CDS YP_007233698.1 431806800 14294568 complement(79593..80051) 1 NC_019908.1 hypothetical protein 80051 14294568 BPP43_00395 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233698.1 79593 R 1042417 CDS YP_007233699.1 431806801 14294569 80186..80284 1 NC_019908.1 hypothetical protein 80284 14294569 BPP43_00400 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233699.1 80186 D 1042417 CDS YP_007233700.1 431806802 14294570 80277..81614 1 NC_019908.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); membrane-bound lytic murein transglycosylase D 81614 14294570 BPP43_00405 Brachyspira pilosicoli P43/6/78 membrane-bound lytic murein transglycosylase D YP_007233700.1 80277 D 1042417 CDS YP_007233701.1 431806803 14294571 81760..82077 1 NC_019908.1 COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 82077 14294571 BPP43_00410 Brachyspira pilosicoli P43/6/78 thioredoxin YP_007233701.1 81760 D 1042417 CDS YP_007233702.1 431806804 14294572 complement(82159..82656) 1 NC_019908.1 COG1666 Uncharacterized protein conserved in bacteria; nucleotide-binding protein 82656 14294572 BPP43_00415 Brachyspira pilosicoli P43/6/78 nucleotide-binding protein YP_007233702.1 82159 R 1042417 CDS YP_007233703.1 431806805 14294573 complement(82692..84152) 1 NC_019908.1 COG0297 Glycogen synthase; glycogen/starch synthase 84152 14294573 BPP43_00420 Brachyspira pilosicoli P43/6/78 glycogen/starch synthase YP_007233703.1 82692 R 1042417 CDS YP_007233704.1 431806806 14294574 complement(84250..84612) 1 NC_019908.1 hypothetical protein 84612 14294574 BPP43_00425 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233704.1 84250 R 1042417 CDS YP_007233705.1 431806807 14294575 84765..86570 1 NC_019908.1 COG1164 Oligoendopeptidase F; peptidase 86570 14294575 BPP43_00430 Brachyspira pilosicoli P43/6/78 peptidase YP_007233705.1 84765 D 1042417 CDS YP_007233706.1 431806808 14294576 86688..86891 1 NC_019908.1 COG2314 Predicted membrane protein; TM2 domain-containing protein 86891 14294576 BPP43_00435 Brachyspira pilosicoli P43/6/78 TM2 domain-containing protein YP_007233706.1 86688 D 1042417 CDS YP_007233707.1 431806809 14294577 87117..87503 1 NC_019908.1 hypothetical protein 87503 14294577 BPP43_00440 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233707.1 87117 D 1042417 CDS YP_007233708.1 431806810 14294578 89635..90225 1 NC_019908.1 COG0290 Translation initiation factor 3 (IF-3); translation initiation factor IF-3 90225 14294578 BPP43_00455 Brachyspira pilosicoli P43/6/78 translation initiation factor IF-3 YP_007233708.1 89635 D 1042417 CDS YP_007233709.1 431806811 14294579 90325..90528 1 NC_019908.1 COG0291 Ribosomal protein L35; 50S ribosomal protein L35 90528 14294579 BPP43_00460 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L35 YP_007233709.1 90325 D 1042417 CDS YP_007233710.1 431806812 14294580 90546..90899 1 NC_019908.1 COG0292 Ribosomal protein L20; 50S ribosomal protein L20 90899 14294580 BPP43_00465 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L20 YP_007233710.1 90546 D 1042417 CDS YP_007233711.1 431806813 14294581 complement(91063..93378) 1 NC_019908.1 COG0209 Ribonucleotide reductase, alpha subunit; ribonucleotide-diphosphate reductase subunit alpha 93378 14294581 BPP43_00470 Brachyspira pilosicoli P43/6/78 ribonucleotide-diphosphate reductase subunit alpha YP_007233711.1 91063 R 1042417 CDS YP_007233712.1 431806814 14294582 complement(93396..94475) 1 NC_019908.1 COG0208 Ribonucleotide reductase, beta subunit; ribonucleotide-diphosphate reductase subunit beta 94475 14294582 BPP43_00475 Brachyspira pilosicoli P43/6/78 ribonucleotide-diphosphate reductase subunit beta YP_007233712.1 93396 R 1042417 CDS YP_007233713.1 431806815 14294583 complement(94866..95804) 1 NC_019908.1 COG0385 Predicted Na+-dependent transporter; transporter 95804 14294583 BPP43_00480 Brachyspira pilosicoli P43/6/78 transporter YP_007233713.1 94866 R 1042417 CDS YP_007233714.1 431806816 14294584 complement(96428..98110) 1 NC_019908.1 COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; dihydroxy-acid dehydratase 98110 14294584 BPP43_00485 Brachyspira pilosicoli P43/6/78 dihydroxy-acid dehydratase YP_007233714.1 96428 R 1042417 CDS YP_007233715.1 431806817 14294585 99228..100856 1 NC_019908.1 COG1233 Phytoene dehydrogenase and related proteins; carotenoid isomerase 100856 14294585 BPP43_00500 Brachyspira pilosicoli P43/6/78 carotenoid isomerase YP_007233715.1 99228 D 1042417 CDS YP_007233716.1 431806818 14294586 100944..101447 1 NC_019908.1 COG4731 Uncharacterized protein conserved in bacteria; hypothetical protein 101447 14294586 BPP43_00505 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233716.1 100944 D 1042417 CDS YP_007233717.1 431806819 14294587 101493..102398 1 NC_019908.1 hypothetical protein 102398 14294587 BPP43_00510 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233717.1 101493 D 1042417 CDS YP_007233718.1 431806820 14294588 complement(102477..103682) 1 NC_019908.1 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; OmpA family outer membrane protein 103682 14294588 BPP43_00515 Brachyspira pilosicoli P43/6/78 OmpA family outer membrane protein YP_007233718.1 102477 R 1042417 CDS YP_007233719.1 431806821 14294589 complement(103684..106506) 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein B 106506 14294589 BPP43_00520 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis protein B YP_007233719.1 103684 R 1042417 CDS YP_007233720.1 431806822 14294590 complement(106563..107975) 1 NC_019908.1 COG0055 F0F1-type ATP synthase, beta subunit; F0F1 ATP synthase subunit beta 107975 14294590 BPP43_00525 Brachyspira pilosicoli P43/6/78 F0F1 ATP synthase subunit beta YP_007233720.1 106563 R 1042417 CDS YP_007233721.1 431806823 14294591 complement(108040..108915) 1 NC_019908.1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; inositol-1-monophosphatase 108915 14294591 BPP43_00530 Brachyspira pilosicoli P43/6/78 inositol-1-monophosphatase YP_007233721.1 108040 R 1042417 CDS YP_007233722.1 431806824 14294592 complement(108942..109724) 1 NC_019908.1 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component; ABC transporter-like permease 109724 14294592 BPP43_00535 Brachyspira pilosicoli P43/6/78 ABC transporter-like permease YP_007233722.1 108942 R 1042417 CDS YP_007233723.1 431806825 14294593 complement(109791..110519) 1 NC_019908.1 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component; ABC transporter ATP-binding protein 110519 14294593 BPP43_00540 Brachyspira pilosicoli P43/6/78 ABC transporter ATP-binding protein YP_007233723.1 109791 R 1042417 CDS YP_007233724.1 431806826 14294594 complement(110536..111510) 1 NC_019908.1 COG1482 Phosphomannose isomerase; mannose-6-phosphate isomerase 111510 14294594 BPP43_00545 Brachyspira pilosicoli P43/6/78 mannose-6-phosphate isomerase YP_007233724.1 110536 R 1042417 CDS YP_007233725.1 431806827 14294595 complement(111856..112875) 1 NC_019908.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; zinc-containing alcohol dehydrogenase 112875 14294595 BPP43_00550 Brachyspira pilosicoli P43/6/78 zinc-containing alcohol dehydrogenase YP_007233725.1 111856 R 1042417 CDS YP_007233726.1 431806828 14294596 complement(113272..115833) 1 NC_019908.1 COG0495 Leucyl-tRNA synthetase; leucyl-tRNA synthetase 115833 14294596 BPP43_00555 Brachyspira pilosicoli P43/6/78 leucyl-tRNA synthetase YP_007233726.1 113272 R 1042417 CDS YP_007233727.1 431806829 14294597 116256..116633 1 NC_019908.1 hypothetical protein 116633 14294597 BPP43_00560 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233727.1 116256 D 1042417 CDS YP_007233728.1 431806830 14294598 116706..117866 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 117866 14294598 BPP43_00565 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007233728.1 116706 D 1042417 CDS YP_007233729.1 431806831 14294599 117993..118850 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 118850 14294599 BPP43_00570 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007233729.1 117993 D 1042417 CDS YP_007233730.1 431806832 14294600 complement(118925..119170) 1 NC_019908.1 hypothetical protein 119170 14294600 BPP43_00575 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233730.1 118925 R 1042417 CDS YP_007233731.1 431806833 14294601 complement(119982..121040) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 121040 14294601 BPP43_00580 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233731.1 119982 R 1042417 CDS YP_007233732.1 431806834 14294602 complement(121178..123028) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 123028 14294602 BPP43_00585 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233732.1 121178 R 1042417 CDS YP_007233733.1 431806835 14294603 complement(123472..125049) 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 125049 14294603 BPP43_00590 Brachyspira pilosicoli P43/6/78 family 5 extracellular solute-binding protein YP_007233733.1 123472 R 1042417 CDS YP_007233734.1 431806836 14294604 125337..126566 1 NC_019908.1 COG1064 Zn-dependent alcohol dehydrogenases; alcohol dehydrogenase 126566 14294604 BPP43_00595 Brachyspira pilosicoli P43/6/78 alcohol dehydrogenase YP_007233734.1 125337 D 1042417 CDS YP_007233735.1 431806837 14294605 127099..128298 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter substrate-binding protein 128298 14294605 BPP43_00600 Brachyspira pilosicoli P43/6/78 oligopeptide ABC transporter substrate-binding protein YP_007233735.1 127099 D 1042417 CDS YP_007233736.1 431806838 14294606 128557..130125 1 NC_019908.1 COG0246 Mannitol-1-phosphate/altronate dehydrogenases; mannitol-1-phosphate/altronate dehydrogenase 130125 14294606 BPP43_00605 Brachyspira pilosicoli P43/6/78 mannitol-1-phosphate/altronate dehydrogenase YP_007233736.1 128557 D 1042417 CDS YP_007233737.1 431806839 14294607 130204..131271 1 NC_019908.1 COG1312 D-mannonate dehydratase; mannonate dehydratase 131271 14294607 BPP43_00610 Brachyspira pilosicoli P43/6/78 mannonate dehydratase YP_007233737.1 130204 D 1042417 CDS YP_007233738.1 431806840 14294608 131355..132761 1 NC_019908.1 COG1904 Glucuronate isomerase; glucuronate isomerase 132761 14294608 BPP43_00615 Brachyspira pilosicoli P43/6/78 glucuronate isomerase YP_007233738.1 131355 D 1042417 CDS YP_007233739.1 431806841 14294609 132861..133493 1 NC_019908.1 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 133493 14294609 BPP43_00620 Brachyspira pilosicoli P43/6/78 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_007233739.1 132861 D 1042417 CDS YP_007233740.1 431806842 14294610 133583..134068 1 NC_019908.1 hypothetical protein 134068 14294610 BPP43_00625 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233740.1 133583 D 1042417 CDS YP_007233741.1 431806843 14294611 134065..134769 1 NC_019908.1 COG1694 Predicted pyrophosphatase; phosphatase and methylase 134769 14294611 BPP43_00630 Brachyspira pilosicoli P43/6/78 phosphatase and methylase YP_007233741.1 134065 D 1042417 CDS YP_007233742.1 431806844 14294612 134762..134848 1 NC_019908.1 phosphatase and methylase 134848 14294612 BPP43_00635 Brachyspira pilosicoli P43/6/78 phosphatase and methylase YP_007233742.1 134762 D 1042417 CDS YP_007233743.1 431806845 14294613 134930..136114 1 NC_019908.1 COG0628 Predicted permease; hypothetical protein 136114 14294613 BPP43_00640 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233743.1 134930 D 1042417 CDS YP_007233744.1 431806846 14294614 136132..137112 1 NC_019908.1 COG0859 ADP-heptose:LPS heptosyltransferase; ADP-heptose:LPS heptosyltransferase II 137112 14294614 BPP43_00645 Brachyspira pilosicoli P43/6/78 ADP-heptose:LPS heptosyltransferase II YP_007233744.1 136132 D 1042417 CDS YP_007233745.1 431806847 14294615 complement(137349..138503) 1 NC_019908.1 COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation); poly-gamma-glutamic biosynthesis protein 138503 14294615 BPP43_00650 Brachyspira pilosicoli P43/6/78 poly-gamma-glutamic biosynthesis protein YP_007233745.1 137349 R 1042417 CDS YP_007233746.1 431806848 14294616 complement(138504..139886) 1 NC_019908.1 COG1253 Hemolysins and related proteins containing CBS domains; hemolysin protein 139886 14294616 BPP43_00655 Brachyspira pilosicoli P43/6/78 hemolysin protein YP_007233746.1 138504 R 1042417 CDS YP_007233747.1 431806849 14294617 complement(139902..140564) 1 NC_019908.1 N-acetylmuramoyl-L-alanine amidase 140564 14294617 BPP43_00660 Brachyspira pilosicoli P43/6/78 N-acetylmuramoyl-L-alanine amidase YP_007233747.1 139902 R 1042417 CDS YP_007233748.1 431806850 14294618 complement(140583..141083) 1 NC_019908.1 COG1406 Predicted inhibitor of MCP methylation, homolog of CheC; chemotaxis protein CheX 141083 14294618 BPP43_00665 Brachyspira pilosicoli P43/6/78 chemotaxis protein CheX YP_007233748.1 140583 R 1042417 CDS YP_007233749.1 431806851 14294619 141322..141717 1 NC_019908.1 hypothetical protein 141717 14294619 BPP43_00670 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233749.1 141322 D 1042417 CDS YP_007233750.1 431806852 14294620 complement(141852..142685) 1 NC_019908.1 hypothetical protein 142685 14294620 BPP43_00675 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233750.1 141852 R 1042417 CDS YP_007233751.1 431806853 14294621 complement(142756..143484) 1 NC_019908.1 COG3034 Uncharacterized protein conserved in bacteria; hypothetical protein 143484 14294621 BPP43_00680 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233751.1 142756 R 1042417 CDS YP_007233752.1 431806854 14294622 143680..145605 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; hypothetical protein 145605 14294622 BPP43_00685 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233752.1 143680 D 1042417 CDS YP_007233753.1 431806855 14294623 145615..145863 1 NC_019908.1 hypothetical protein 145863 14294623 BPP43_00690 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233753.1 145615 D 1042417 CDS YP_007233754.1 431806856 14294624 145904..146272 1 NC_019908.1 COG0784 FOG: CheY-like receiver; chemotaxis response regulator CheY 146272 14294624 BPP43_00695 Brachyspira pilosicoli P43/6/78 chemotaxis response regulator CheY YP_007233754.1 145904 D 1042417 CDS YP_007233755.1 431806857 14294625 146318..148429 1 NC_019908.1 COG0643 Chemotaxis protein histidine kinase and related kinases; chemotaxis histidine kinase CheA 148429 14294625 BPP43_00700 Brachyspira pilosicoli P43/6/78 chemotaxis histidine kinase CheA YP_007233755.1 146318 D 1042417 CDS YP_007233756.1 431806858 14294626 148444..148977 1 NC_019908.1 COG0835 Chemotaxis signal transduction protein; chemotaxis protein CheW 148977 14294626 BPP43_00705 Brachyspira pilosicoli P43/6/78 chemotaxis protein CheW YP_007233756.1 148444 D 1042417 CDS YP_007233757.1 431806859 14294627 148988..149833 1 NC_019908.1 COG1352 Methylase of chemotaxis methyl-accepting proteins; chemotaxis protein methyltransferase CheR 149833 14294627 BPP43_00710 Brachyspira pilosicoli P43/6/78 chemotaxis protein methyltransferase CheR YP_007233757.1 148988 D 1042417 CDS YP_007233758.1 431806860 14294628 149850..150443 1 NC_019908.1 COG1871 Chemotaxis protein; stimulates methylation of MCP proteins; chemotaxis protein CheD 150443 14294628 BPP43_00715 Brachyspira pilosicoli P43/6/78 chemotaxis protein CheD YP_007233758.1 149850 D 1042417 CDS YP_007233759.1 431806861 14294629 150461..151594 1 NC_019908.1 COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; response regulator receiver modulated CheB methylesterase 151594 14294629 BPP43_00720 Brachyspira pilosicoli P43/6/78 response regulator receiver modulated CheB methylesterase YP_007233759.1 150461 D 1042417 CDS YP_007233760.1 431806862 14294630 151602..152390 1 NC_019908.1 hypothetical protein 152390 14294630 BPP43_00725 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233760.1 151602 D 1042417 CDS YP_007233761.1 431806863 14294631 152721..153746 1 NC_019908.1 COG0533 Metal-dependent proteases with possible chaperone activity; O-sialoglycoprotein endopeptidase 153746 14294631 BPP43_00730 Brachyspira pilosicoli P43/6/78 O-sialoglycoprotein endopeptidase YP_007233761.1 152721 D 1042417 CDS YP_007233762.1 431806864 14294632 153765..154343 1 NC_019908.1 COG0457 FOG: TPR repeat; O-linked GlcNAc transferase 154343 14294632 BPP43_00735 Brachyspira pilosicoli P43/6/78 O-linked GlcNAc transferase YP_007233762.1 153765 D 1042417 CDS YP_007233763.1 431806865 14294633 complement(154340..155038) 1 NC_019908.1 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; nitrate transport ATP-binding protein, NrtD 155038 14294633 BPP43_00740 Brachyspira pilosicoli P43/6/78 nitrate transport ATP-binding protein, NrtD YP_007233763.1 154340 R 1042417 CDS YP_007233764.1 431806866 14294634 complement(155028..155753) 1 NC_019908.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; binding-protein-dependent transport system inner membrane protein 155753 14294634 BPP43_00745 Brachyspira pilosicoli P43/6/78 binding-protein-dependent transport system inner membrane protein YP_007233764.1 155028 R 1042417 CDS YP_007233765.1 431806867 14294635 complement(155859..156434) 1 NC_019908.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase 156434 14294635 BPP43_00750 Brachyspira pilosicoli P43/6/78 acetyltransferase YP_007233765.1 155859 R 1042417 CDS YP_007233766.1 431806868 14294636 complement(156510..157391) 1 NC_019908.1 COG1760 L-serine deaminase; L-serine dehydratase iron-sulfur-dependent subunit alpha 157391 14294636 BPP43_00755 Brachyspira pilosicoli P43/6/78 L-serine dehydratase iron-sulfur-dependent subunit alpha YP_007233766.1 156510 R 1042417 CDS YP_007233767.1 431806869 14294637 complement(157516..158091) 1 NC_019908.1 COG1760 L-serine deaminase; L-serine dehydratase iron-sulfur-dependent subunit beta 158091 14294637 BPP43_00760 Brachyspira pilosicoli P43/6/78 L-serine dehydratase iron-sulfur-dependent subunit beta YP_007233767.1 157516 R 1042417 CDS YP_007233768.1 431806870 14294638 158426..159352 1 NC_019908.1 COG4974 Site-specific recombinase XerD; tyrosine recombinase XerD 159352 14294638 BPP43_00765 Brachyspira pilosicoli P43/6/78 tyrosine recombinase XerD YP_007233768.1 158426 D 1042417 CDS YP_007233769.1 431806871 14294639 159385..161676 1 NC_019908.1 hypothetical protein 161676 14294639 BPP43_00770 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233769.1 159385 D 1042417 CDS YP_007233770.1 431806872 14294640 161922..162395 1 NC_019908.1 hypothetical protein 162395 14294640 BPP43_00775 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233770.1 161922 D 1042417 CDS YP_007233771.1 431806873 14294641 162457..162960 1 NC_019908.1 COG0219 Predicted rRNA methylase (SpoU class); RNA methyltransferase 162960 14294641 BPP43_00780 Brachyspira pilosicoli P43/6/78 RNA methyltransferase YP_007233771.1 162457 D 1042417 CDS YP_007233772.1 431806874 14294642 complement(164733..165416) 1 NC_019908.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional regulator 165416 14294642 BPP43_00795 Brachyspira pilosicoli P43/6/78 transcriptional regulator YP_007233772.1 164733 R 1042417 CDS YP_007233773.1 431806875 14294643 165753..167108 1 NC_019908.1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; glutamate synthase 167108 14294643 BPP43_00800 Brachyspira pilosicoli P43/6/78 glutamate synthase YP_007233773.1 165753 D 1042417 CDS YP_007233774.1 431806876 14294644 167275..169569 1 NC_019908.1 COG1449 Alpha-amylase/alpha-mannosidase; glycoside hydrolase family protein 169569 14294644 BPP43_00805 Brachyspira pilosicoli P43/6/78 glycoside hydrolase family protein YP_007233774.1 167275 D 1042417 CDS YP_007233775.1 431806877 14294645 complement(169566..169991) 1 NC_019908.1 hypothetical protein 169991 14294645 BPP43_00810 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233775.1 169566 R 1042417 CDS YP_007233776.1 431806878 14294646 complement(169988..170395) 1 NC_019908.1 positive regulator of sigma E RseC/MucC 170395 14294646 BPP43_00815 Brachyspira pilosicoli P43/6/78 positive regulator of sigma E RseC/MucC YP_007233776.1 169988 R 1042417 CDS YP_007233777.1 431806879 14294647 complement(170547..171779) 1 NC_019908.1 COG1301 Na+/H+-dicarboxylate symporters; H(+):sodium-glutamate symporter 171779 14294647 BPP43_00820 Brachyspira pilosicoli P43/6/78 H(+):sodium-glutamate symporter YP_007233777.1 170547 R 1042417 CDS YP_007233778.1 431806880 14294648 complement(171800..172999) 1 NC_019908.1 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; aspartate aminotransferase 172999 14294648 BPP43_00825 Brachyspira pilosicoli P43/6/78 aspartate aminotransferase YP_007233778.1 171800 R 1042417 CDS YP_007233779.1 431806881 14294649 173167..173844 1 NC_019908.1 COG2964 Uncharacterized protein conserved in bacteria; hypothetical protein 173844 14294649 BPP43_00830 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233779.1 173167 D 1042417 CDS YP_007233780.1 431806882 14294650 complement(173911..175122) 1 NC_019908.1 COG1301 Na+/H+-dicarboxylate symporters; H(+):sodium-dicarboxylate symporter 175122 14294650 BPP43_00835 Brachyspira pilosicoli P43/6/78 H(+):sodium-dicarboxylate symporter YP_007233780.1 173911 R 1042417 CDS YP_007233781.1 431806883 14294651 complement(175235..175966) 1 NC_019908.1 COG1413 FOG: HEAT repeat; peptidase C14 175966 14294651 BPP43_00840 Brachyspira pilosicoli P43/6/78 peptidase C14 YP_007233781.1 175235 R 1042417 CDS YP_007233782.1 431806884 14294652 176151..177545 1 NC_019908.1 COG3412 Uncharacterized protein conserved in bacteria; phosphoenolpyruvate-protein phosphotransferase 177545 14294652 BPP43_00845 Brachyspira pilosicoli P43/6/78 phosphoenolpyruvate-protein phosphotransferase YP_007233782.1 176151 D 1042417 CDS YP_007233783.1 431806885 14294653 177637..178110 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 178110 14294653 BPP43_00850 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007233783.1 177637 D 1042417 CDS YP_007233784.1 431806886 14294654 complement(178107..178346) 1 NC_019908.1 hypothetical protein 178346 14294654 BPP43_00855 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233784.1 178107 R 1042417 CDS YP_007233785.1 431806887 14294655 178546..179301 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat containing protein 179301 14294655 BPP43_00860 Brachyspira pilosicoli P43/6/78 ankyrin repeat containing protein YP_007233785.1 178546 D 1042417 CDS YP_007233786.1 431806888 14294656 179328..180317 1 NC_019908.1 COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 180317 14294656 BPP43_00865 Brachyspira pilosicoli P43/6/78 UDP-glucose 4-epimerase YP_007233786.1 179328 D 1042417 CDS YP_007233787.1 431806889 14294657 180317..181030 1 NC_019908.1 COG0566 rRNA methylases; TrmH family RNA methyltransferase 181030 14294657 BPP43_00870 Brachyspira pilosicoli P43/6/78 TrmH family RNA methyltransferase YP_007233787.1 180317 D 1042417 CDS YP_007233788.1 431806890 14294658 complement(181399..183441) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 183441 14294658 BPP43_00875 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233788.1 181399 R 1042417 CDS YP_007233789.1 431806891 14294659 183762..184496 1 NC_019908.1 COG4760 Predicted membrane protein; hypothetical protein 184496 14294659 BPP43_00880 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233789.1 183762 D 1042417 CDS YP_007233790.1 431806892 14294660 complement(184562..185104) 1 NC_019908.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase 185104 14294660 BPP43_00885 Brachyspira pilosicoli P43/6/78 acetyltransferase YP_007233790.1 184562 R 1042417 CDS YP_007233791.1 431806893 14294661 185262..186149 1 NC_019908.1 COG0142 Geranylgeranyl pyrophosphate synthase; geranylgeranyl pyrophosphate synthase 186149 14294661 BPP43_00890 Brachyspira pilosicoli P43/6/78 geranylgeranyl pyrophosphate synthase YP_007233791.1 185262 D 1042417 CDS YP_007233792.1 431806894 14294662 186150..187997 1 NC_019908.1 COG2604 Uncharacterized protein conserved in bacteria; hypothetical protein 187997 14294662 BPP43_00895 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233792.1 186150 D 1042417 CDS YP_007233793.1 431806895 14294663 188113..189492 1 NC_019908.1 hypothetical protein 189492 14294663 BPP43_00900 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233793.1 188113 D 1042417 CDS YP_007233794.1 431806896 14294664 complement(189553..190215) 1 NC_019908.1 COG1272 Predicted membrane protein, hemolysin III homolog; hemolysin III 190215 14294664 BPP43_00905 Brachyspira pilosicoli P43/6/78 hemolysin III YP_007233794.1 189553 R 1042417 CDS YP_007233795.1 431806897 14294665 complement(190306..190929) 1 NC_019908.1 hypothetical protein 190929 14294665 BPP43_00910 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233795.1 190306 R 1042417 CDS YP_007233796.1 431806898 14294666 191059..191643 1 NC_019908.1 COG0637 Predicted phosphatase/phosphohexomutase; hydrolase 191643 14294666 BPP43_00915 Brachyspira pilosicoli P43/6/78 hydrolase YP_007233796.1 191059 D 1042417 CDS YP_007233797.1 431806899 14294667 complement(191734..192846) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 192846 14294667 BPP43_00920 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233797.1 191734 R 1042417 CDS YP_007233798.1 431806900 14294668 complement(192974..193777) 1 NC_019908.1 hypothetical protein 193777 14294668 BPP43_00925 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233798.1 192974 R 1042417 CDS YP_007233799.1 431806901 14294669 complement(193806..194576) 1 NC_019908.1 hypothetical protein 194576 14294669 BPP43_00930 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233799.1 193806 R 1042417 CDS YP_007233800.1 431806902 14294670 complement(194591..195355) 1 NC_019908.1 hypothetical protein 195355 14294670 BPP43_00935 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233800.1 194591 R 1042417 CDS YP_007233801.1 431806903 14294671 195583..195846 1 NC_019908.1 hypothetical protein 195846 14294671 BPP43_00940 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233801.1 195583 D 1042417 CDS YP_007233802.1 431806904 14294672 195875..197254 1 NC_019908.1 hypothetical protein 197254 14294672 BPP43_00945 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233802.1 195875 D 1042417 CDS YP_007233803.1 431806905 14294673 197822..199288 1 NC_019908.1 hypothetical protein 199288 14294673 BPP43_00950 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233803.1 197822 D 1042417 CDS YP_007233804.1 431806906 14294674 199291..202542 1 NC_019908.1 hypothetical protein 202542 14294674 BPP43_00955 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233804.1 199291 D 1042417 CDS YP_007233805.1 431806907 14294675 202552..203154 1 NC_019908.1 hypothetical protein 203154 14294675 BPP43_00960 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233805.1 202552 D 1042417 CDS YP_007233806.1 431806908 14294676 204613..205371 1 NC_019908.1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; metal-dependent hydrolase 205371 14294676 BPP43_00975 Brachyspira pilosicoli P43/6/78 metal-dependent hydrolase YP_007233806.1 204613 D 1042417 CDS YP_007233807.1 431806909 14294677 205462..206928 1 NC_019908.1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system N-acetylglucosamine-specific transporter subunit IIBC NagE 206928 14294677 BPP43_00980 Brachyspira pilosicoli P43/6/78 PTS system N-acetylglucosamine-specific transporter subunit IIBC NagE YP_007233807.1 205462 D 1042417 CDS YP_007233808.1 431806910 14294678 207098..208219 1 NC_019908.1 COG0516 IMP dehydrogenase/GMP reductase; inosine-5-monophosphate dehydrogenase 208219 14294678 BPP43_00985 Brachyspira pilosicoli P43/6/78 inosine-5-monophosphate dehydrogenase YP_007233808.1 207098 D 1042417 CDS YP_007233809.1 431806911 14294679 complement(208464..209615) 1 NC_019908.1 COG0126 3-phosphoglycerate kinase; phosphoglycerate kinase 209615 14294679 BPP43_00990 Brachyspira pilosicoli P43/6/78 phosphoglycerate kinase YP_007233809.1 208464 R 1042417 CDS YP_007233810.1 431806912 14294680 complement(209772..210815) 1 NC_019908.1 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 210815 14294680 BPP43_00995 Brachyspira pilosicoli P43/6/78 glyceraldehyde-3-phosphate dehydrogenase YP_007233810.1 209772 R 1042417 CDS YP_007233811.1 431806913 14294681 211045..211512 1 NC_019908.1 hypothetical protein 211512 14294681 BPP43_01000 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233811.1 211045 D 1042417 CDS YP_007233812.1 431806914 14294682 complement(211574..212491) 1 NC_019908.1 COG1073 Hydrolases of the alpha/beta superfamily; hydrolase of the alpha beta superfamily protein 212491 14294682 BPP43_01005 Brachyspira pilosicoli P43/6/78 hydrolase of the alpha beta superfamily protein YP_007233812.1 211574 R 1042417 CDS YP_007233813.1 431806915 14294683 complement(212513..213253) 1 NC_019908.1 hypothetical protein 213253 14294683 BPP43_01010 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233813.1 212513 R 1042417 CDS YP_007233814.1 431806916 14294684 complement(213308..213697) 1 NC_019908.1 COG0799 Uncharacterized homolog of plant Iojap protein; hypothetical protein 213697 14294684 BPP43_01015 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233814.1 213308 R 1042417 CDS YP_007233815.1 431806917 14294685 complement(213684..214901) 1 NC_019908.1 COG1316 Transcriptional regulator; hypothetical protein 214901 14294685 BPP43_01020 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233815.1 213684 R 1042417 CDS YP_007233816.1 431806918 14294688 215334..215699 1 NC_019908.1 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; methionine sulfoxide reductase B 215699 14294688 BPP43_01025 Brachyspira pilosicoli P43/6/78 methionine sulfoxide reductase B YP_007233816.1 215334 D 1042417 CDS YP_007233817.1 431806919 14294689 215744..217342 1 NC_019908.1 COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain; potassium/proton antiporter 217342 14294689 BPP43_01030 Brachyspira pilosicoli P43/6/78 potassium/proton antiporter YP_007233817.1 215744 D 1042417 CDS YP_007233818.1 431806920 14294690 217454..219085 1 NC_019908.1 COG0459 Chaperonin GroEL (HSP60 family); chaperonin GroEL 219085 14294690 BPP43_01035 Brachyspira pilosicoli P43/6/78 chaperonin GroEL YP_007233818.1 217454 D 1042417 CDS YP_007233819.1 431806921 14294691 219194..219679 1 NC_019908.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 219679 14294691 BPP43_01040 Brachyspira pilosicoli P43/6/78 N-acetyltransferase GCN5 YP_007233819.1 219194 D 1042417 CDS YP_007233820.1 431806922 14294692 221429..222958 1 NC_019908.1 COG1418 Predicted HD superfamily hydrolase; metal-dependent phosphohydrolase 222958 14294692 BPP43_01055 Brachyspira pilosicoli P43/6/78 metal-dependent phosphohydrolase YP_007233820.1 221429 D 1042417 CDS YP_007233821.1 431806923 14294693 223798..224805 1 NC_019908.1 hypothetical protein 224805 14294693 BPP43_01070 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233821.1 223798 D 1042417 CDS YP_007233822.1 431806924 14294694 225003..225680 1 NC_019908.1 hypothetical protein 225680 14294694 BPP43_01075 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233822.1 225003 D 1042417 CDS YP_007233823.1 431806925 14294695 225720..226283 1 NC_019908.1 COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism; metal-dependent phosphohydrolase 226283 14294695 BPP43_01080 Brachyspira pilosicoli P43/6/78 metal-dependent phosphohydrolase YP_007233823.1 225720 D 1042417 CDS YP_007233824.1 431806926 14294696 226295..227395 1 NC_019908.1 COG2262 GTPases; GTP-binding HSR1-like protein 227395 14294696 BPP43_01085 Brachyspira pilosicoli P43/6/78 GTP-binding HSR1-like protein YP_007233824.1 226295 D 1042417 CDS YP_007233825.1 431806927 14294697 227674..229410 1 NC_019908.1 COG0442 Prolyl-tRNA synthetase; prolyl-tRNA synthetase 229410 14294697 BPP43_01090 Brachyspira pilosicoli P43/6/78 prolyl-tRNA synthetase YP_007233825.1 227674 D 1042417 CDS YP_007233826.1 431806928 14294698 229426..229857 1 NC_019908.1 COG0456 Acetyltransferases; ribosomal-protein-alanine acetyltransferase 229857 14294698 BPP43_01095 Brachyspira pilosicoli P43/6/78 ribosomal-protein-alanine acetyltransferase YP_007233826.1 229426 D 1042417 CDS YP_007233827.1 431806929 14294699 complement(229864..230934) 1 NC_019908.1 COG0795 Predicted permeases; permease 230934 14294699 BPP43_01100 Brachyspira pilosicoli P43/6/78 permease YP_007233827.1 229864 R 1042417 CDS YP_007233828.1 431806930 14294700 complement(230944..231822) 1 NC_019908.1 COG1655 Uncharacterized protein conserved in bacteria; hypothetical protein 231822 14294700 BPP43_01105 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233828.1 230944 R 1042417 CDS YP_007233829.1 431806931 14294701 complement(232989..234545) 1 NC_019908.1 COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); N-acetylglucosamine-1-phosphate uridyltransferase 234545 14294701 BPP43_01120 Brachyspira pilosicoli P43/6/78 N-acetylglucosamine-1-phosphate uridyltransferase YP_007233829.1 232989 R 1042417 CDS YP_007233830.1 431806932 14294702 complement(234571..235101) 1 NC_019908.1 hypothetical protein 235101 14294702 BPP43_01125 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233830.1 234571 R 1042417 CDS YP_007233831.1 431806933 14294703 235244..237871 1 NC_019908.1 COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain; 5-methyltetrahydrofolate--homocysteine methyltransferase 237871 14294703 BPP43_01130 Brachyspira pilosicoli P43/6/78 5-methyltetrahydrofolate--homocysteine methyltransferase YP_007233831.1 235244 D 1042417 CDS YP_007233832.1 431806934 14294704 238169..238975 1 NC_019908.1 COG1410 Methionine synthase I, cobalamin-binding domain; 5-methyltetrahydrofolate--homocysteine methyltransferase 238975 14294704 BPP43_01135 Brachyspira pilosicoli P43/6/78 5-methyltetrahydrofolate--homocysteine methyltransferase YP_007233832.1 238169 D 1042417 CDS YP_007233833.1 431806935 14294705 239180..239386 1 NC_019908.1 hypothetical protein 239386 14294705 BPP43_01140 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233833.1 239180 D 1042417 CDS YP_007233834.1 431806936 14294706 complement(239487..240410) 1 NC_019908.1 COG0685 5,10-methylenetetrahydrofolate reductase; methylenetetrahydrofolate reductase 240410 14294706 BPP43_01145 Brachyspira pilosicoli P43/6/78 methylenetetrahydrofolate reductase YP_007233834.1 239487 R 1042417 CDS YP_007233835.1 431806937 14294707 240563..241942 1 NC_019908.1 COG0534 Na+-driven multidrug efflux pump; Na+-driven multidrug efflux pump 241942 14294707 BPP43_01150 Brachyspira pilosicoli P43/6/78 Na+-driven multidrug efflux pump YP_007233835.1 240563 D 1042417 CDS YP_007233836.1 431806938 14294708 242079..242273 1 NC_019908.1 hypothetical protein 242273 14294708 BPP43_01155 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233836.1 242079 D 1042417 CDS YP_007233837.1 431806939 14294709 242277..243080 1 NC_019908.1 COG0455 ATPases involved in chromosome partitioning; flagellar biosynthesis protein FlhG 243080 14294709 BPP43_01160 Brachyspira pilosicoli P43/6/78 flagellar biosynthesis protein FlhG YP_007233837.1 242277 D 1042417 CDS YP_007233838.1 431806940 14294710 243217..244506 1 NC_019908.1 COG0477 Permeases of the major facilitator superfamily; MFS superfamily transporter 244506 14294710 BPP43_01165 Brachyspira pilosicoli P43/6/78 MFS superfamily transporter YP_007233838.1 243217 D 1042417 CDS YP_007233839.1 431806941 14294711 244535..245272 1 NC_019908.1 COG0584 Glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase family protein 245272 14294711 BPP43_01170 Brachyspira pilosicoli P43/6/78 glycerophosphoryl diester phosphodiesterase family protein YP_007233839.1 244535 D 1042417 CDS YP_007233840.1 431806942 14294712 complement(245343..245822) 1 NC_019908.1 hypothetical protein 245822 14294712 BPP43_01175 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233840.1 245343 R 1042417 CDS YP_007233841.1 431806943 14294713 246026..246556 1 NC_019908.1 COG3247 Uncharacterized conserved protein; hypothetical protein 246556 14294713 BPP43_01180 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233841.1 246026 D 1042417 CDS YP_007233842.1 431806944 14294714 246677..248932 1 NC_019908.1 COG1048 Aconitase A; aconitate hydratase 248932 14294714 BPP43_01185 Brachyspira pilosicoli P43/6/78 aconitate hydratase YP_007233842.1 246677 D 1042417 CDS YP_007233843.1 431806945 14294715 249100..250359 1 NC_019908.1 COG0538 Isocitrate dehydrogenases; isocitrate dehydrogenase 250359 14294715 BPP43_01190 Brachyspira pilosicoli P43/6/78 isocitrate dehydrogenase YP_007233843.1 249100 D 1042417 CDS YP_007233844.1 431806946 14294716 250385..251728 1 NC_019908.1 COG0372 Citrate synthase; citrate synthase 251728 14294716 BPP43_01195 Brachyspira pilosicoli P43/6/78 citrate synthase YP_007233844.1 250385 D 1042417 CDS YP_007233845.1 431806947 14294717 complement(252334..252954) 1 NC_019908.1 COG0560 Phosphoserine phosphatase; phosphoserine phosphatase SerB 252954 14294717 BPP43_01200 Brachyspira pilosicoli P43/6/78 phosphoserine phosphatase SerB YP_007233845.1 252334 R 1042417 CDS YP_007233846.1 431806948 14294718 complement(252967..254571) 1 NC_019908.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; D-3-phosphoglycerate dehydrogenase 254571 14294718 BPP43_01205 Brachyspira pilosicoli P43/6/78 D-3-phosphoglycerate dehydrogenase YP_007233846.1 252967 R 1042417 CDS YP_007233847.1 431806949 14294719 complement(254703..255827) 1 NC_019908.1 COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; serine pyruvate aspartate aminotransferase-like enzyme 255827 14294719 BPP43_01210 Brachyspira pilosicoli P43/6/78 serine pyruvate aspartate aminotransferase-like enzyme YP_007233847.1 254703 R 1042417 CDS YP_007233848.1 431806950 14294720 complement(255985..256443) 1 NC_019908.1 COG1970 Large-conductance mechanosensitive channel; large conductance mechanosensitive channel protein 256443 14294720 BPP43_01215 Brachyspira pilosicoli P43/6/78 large conductance mechanosensitive channel protein YP_007233848.1 255985 R 1042417 CDS YP_007233849.1 431806951 14294721 256754..257155 1 NC_019908.1 COG0071 Molecular chaperone (small heat shock protein); heat shock protein 257155 14294721 BPP43_01220 Brachyspira pilosicoli P43/6/78 heat shock protein YP_007233849.1 256754 D 1042417 CDS YP_007233850.1 431806952 14294722 257189..257581 1 NC_019908.1 COG0071 Molecular chaperone (small heat shock protein); heat shock protein 257581 14294722 BPP43_01225 Brachyspira pilosicoli P43/6/78 heat shock protein YP_007233850.1 257189 D 1042417 CDS YP_007233851.1 431806953 14294723 complement(259931..262348) 1 NC_019908.1 COG5009 Membrane carboxypeptidase/penicillin-binding protein; penicillin-binding protein 1A 262348 14294723 BPP43_01240 Brachyspira pilosicoli P43/6/78 penicillin-binding protein 1A YP_007233851.1 259931 R 1042417 CDS YP_007233852.1 431806954 14294724 complement(262442..264214) 1 NC_019908.1 COG2203 FOG: GAF domain; sigma factor regulatory protein 264214 14294724 BPP43_01245 Brachyspira pilosicoli P43/6/78 sigma factor regulatory protein YP_007233852.1 262442 R 1042417 CDS YP_007233853.1 431806955 14294725 complement(264555..265715) 1 NC_019908.1 COG0738 Fucose permease; major facilitator superfamily protein 265715 14294725 BPP43_01250 Brachyspira pilosicoli P43/6/78 major facilitator superfamily protein YP_007233853.1 264555 R 1042417 CDS YP_007233854.1 431806956 14294726 265885..266931 1 NC_019908.1 COG1162 Predicted GTPases; ribosome-associated GTPase 266931 14294726 BPP43_01255 Brachyspira pilosicoli P43/6/78 ribosome-associated GTPase YP_007233854.1 265885 D 1042417 CDS YP_007233855.1 431806957 14294727 267188..267622 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 267622 14294727 BPP43_01260 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007233855.1 267188 D 1042417 CDS YP_007233856.1 431806958 14294728 267801..268259 1 NC_019908.1 COG3187 Heat shock protein; heat shock protein HslJ 268259 14294728 BPP43_01265 Brachyspira pilosicoli P43/6/78 heat shock protein HslJ YP_007233856.1 267801 D 1042417 CDS YP_007233857.1 431806959 14294729 268482..269417 1 NC_019908.1 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 269417 14294729 BPP43_01270 Brachyspira pilosicoli P43/6/78 multidrug ABC transporter ATPase YP_007233857.1 268482 D 1042417 CDS YP_007233858.1 431806960 14294730 269417..270139 1 NC_019908.1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component; ABC transporter permease 270139 14294730 BPP43_01275 Brachyspira pilosicoli P43/6/78 ABC transporter permease YP_007233858.1 269417 D 1042417 CDS YP_007233859.1 431806961 14294731 270164..271162 1 NC_019908.1 hypothetical protein 271162 14294731 BPP43_01280 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233859.1 270164 D 1042417 CDS YP_007233860.1 431806962 14294732 271192..271749 1 NC_019908.1 COG0558 Phosphatidylglycerophosphate synthase; CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase 271749 14294732 BPP43_01285 Brachyspira pilosicoli P43/6/78 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase YP_007233860.1 271192 D 1042417 CDS YP_007233861.1 431806963 14294733 complement(272224..273570) 1 NC_019908.1 COG0312 Predicted Zn-dependent proteases and their inactivated homologs; peptidase U62 273570 14294733 BPP43_01290 Brachyspira pilosicoli P43/6/78 peptidase U62 YP_007233861.1 272224 R 1042417 CDS YP_007233862.1 431806964 14294734 complement(273574..274962) 1 NC_019908.1 COG0312 Predicted Zn-dependent proteases and their inactivated homologs; peptidase 274962 14294734 BPP43_01295 Brachyspira pilosicoli P43/6/78 peptidase YP_007233862.1 273574 R 1042417 CDS YP_007233863.1 431806965 14294735 complement(274965..275936) 1 NC_019908.1 hypothetical protein 275936 14294735 BPP43_01300 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233863.1 274965 R 1042417 CDS YP_007233864.1 431806966 14294736 276053..276982 1 NC_019908.1 COG0042 tRNA-dihydrouridine synthase; dihydrouridine synthase like protein 276982 14294736 BPP43_01305 Brachyspira pilosicoli P43/6/78 dihydrouridine synthase like protein YP_007233864.1 276053 D 1042417 CDS YP_007233865.1 431806967 14294737 complement(277022..278260) 1 NC_019908.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 278260 14294737 BPP43_01310 Brachyspira pilosicoli P43/6/78 major facilitator superfamily protein YP_007233865.1 277022 R 1042417 CDS YP_007233866.1 431806968 14294738 278375..280387 1 NC_019908.1 hypothetical protein 280387 14294738 BPP43_01315 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233866.1 278375 D 1042417 CDS YP_007233867.1 431806969 14294739 complement(280384..281541) 1 NC_019908.1 hypothetical protein 281541 14294739 BPP43_01320 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233867.1 280384 R 1042417 CDS YP_007233868.1 431806970 14294740 complement(281558..282058) 1 NC_019908.1 COG4186 Predicted phosphoesterase or phosphohydrolase; phosphoesterase or phosphohydrolase 282058 14294740 BPP43_01325 Brachyspira pilosicoli P43/6/78 phosphoesterase or phosphohydrolase YP_007233868.1 281558 R 1042417 CDS YP_007233869.1 431806971 14294741 complement(282065..283366) 1 NC_019908.1 COG1004 Predicted UDP-glucose 6-dehydrogenase; UDP-glucose 6-dehydrogenase 283366 14294741 BPP43_01330 Brachyspira pilosicoli P43/6/78 UDP-glucose 6-dehydrogenase YP_007233869.1 282065 R 1042417 CDS YP_007233870.1 431806972 14294742 complement(285913..286914) 1 NC_019908.1 COG0240 Glycerol-3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase 286914 14294742 BPP43_01345 Brachyspira pilosicoli P43/6/78 glycerol-3-phosphate dehydrogenase YP_007233870.1 285913 R 1042417 CDS YP_007233871.1 431806973 14294743 complement(286960..287403) 1 NC_019908.1 hypothetical protein 287403 14294743 BPP43_01350 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233871.1 286960 R 1042417 CDS YP_007233872.1 431806974 14294744 complement(287475..287891) 1 NC_019908.1 hypothetical protein 287891 14294744 BPP43_01355 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233872.1 287475 R 1042417 CDS YP_007233873.1 431806975 14294745 complement(287963..288412) 1 NC_019908.1 hypothetical protein 288412 14294745 BPP43_01360 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233873.1 287963 R 1042417 CDS YP_007233874.1 431806976 14294746 complement(288430..288843) 1 NC_019908.1 hypothetical protein 288843 14294746 BPP43_01365 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233874.1 288430 R 1042417 CDS YP_007233875.1 431806977 14294747 complement(288955..289740) 1 NC_019908.1 COG0561 Predicted hydrolases of the HAD superfamily; hydrolase 3 haloacid dehalogenase-like hydrolase 289740 14294747 BPP43_01370 Brachyspira pilosicoli P43/6/78 hydrolase 3 haloacid dehalogenase-like hydrolase YP_007233875.1 288955 R 1042417 CDS YP_007233876.1 431806978 14294748 complement(289766..290563) 1 NC_019908.1 COG0561 Predicted hydrolases of the HAD superfamily; hydrolase 3 haloacid dehalogenase-like hydrolase 290563 14294748 BPP43_01375 Brachyspira pilosicoli P43/6/78 hydrolase 3 haloacid dehalogenase-like hydrolase YP_007233876.1 289766 R 1042417 CDS YP_007233877.1 431806979 14294749 complement(293347..295110) 1 NC_019908.1 hypothetical protein 295110 14294749 BPP43_01400 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233877.1 293347 R 1042417 CDS YP_007233878.1 431806980 14294750 complement(295150..295962) 1 NC_019908.1 COG1126 ABC-type polar amino acid transport system, ATPase component; hypothetical protein 295962 14294750 BPP43_01405 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233878.1 295150 R 1042417 CDS YP_007233879.1 431806981 14294751 296328..296741 1 NC_019908.1 COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein 296741 14294751 BPP43_01410 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233879.1 296328 D 1042417 CDS YP_007233880.1 431806982 14294752 296738..297346 1 NC_019908.1 COG0353 Recombinational DNA repair protein (RecF pathway); recombination protein RecR 297346 14294752 BPP43_01415 Brachyspira pilosicoli P43/6/78 recombination protein RecR YP_007233880.1 296738 D 1042417 CDS YP_007233881.1 431806983 14294753 complement(297717..299516) 1 NC_019908.1 COG3276 Selenocysteine-specific translation elongation factor; selenocysteine specific translation elongation factor 299516 14294753 BPP43_01420 Brachyspira pilosicoli P43/6/78 selenocysteine specific translation elongation factor YP_007233881.1 297717 R 1042417 CDS YP_007233882.1 431806984 14294754 complement(299582..300928) 1 NC_019908.1 COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; selenocysteine synthase 300928 14294754 BPP43_01425 Brachyspira pilosicoli P43/6/78 selenocysteine synthase YP_007233882.1 299582 R 1042417 CDS YP_007233883.1 431806985 14294755 complement(301191..301514) 1 NC_019908.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); anti-sigma factor antagonist 301514 14294755 BPP43_01430 Brachyspira pilosicoli P43/6/78 anti-sigma factor antagonist YP_007233883.1 301191 R 1042417 CDS YP_007233884.1 431806986 14294757 301998..302123 1 NC_019908.1 hypothetical protein 302123 14294757 BPP43_01435 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233884.1 301998 D 1042417 CDS YP_007233885.1 431806987 14294758 302120..303616 1 NC_019908.1 COG0591 Na+/proline symporter; sodium solute symporter 303616 14294758 BPP43_01440 Brachyspira pilosicoli P43/6/78 sodium solute symporter YP_007233885.1 302120 D 1042417 CDS YP_007233886.1 431806988 14294759 complement(303636..304190) 1 NC_019908.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; ribosomal-protein-S5-alanine N-acetyltransferase 304190 14294759 BPP43_01445 Brachyspira pilosicoli P43/6/78 ribosomal-protein-S5-alanine N-acetyltransferase YP_007233886.1 303636 R 1042417 CDS YP_007233887.1 431806989 14294760 complement(304199..304720) 1 NC_019908.1 COG0350 Methylated DNA-protein cysteine methyltransferase; methylated-DNA--protein-cysteine methyltransferase 304720 14294760 BPP43_01450 Brachyspira pilosicoli P43/6/78 methylated-DNA--protein-cysteine methyltransferase YP_007233887.1 304199 R 1042417 CDS YP_007233888.1 431806990 14294761 complement(304717..305358) 1 NC_019908.1 COG1335 Amidases related to nicotinamidase; bifunctional pyrazinamidase/nicotinamidase 305358 14294761 BPP43_01455 Brachyspira pilosicoli P43/6/78 bifunctional pyrazinamidase/nicotinamidase YP_007233888.1 304717 R 1042417 CDS YP_007233889.1 431806991 14294762 complement(305381..305953) 1 NC_019908.1 COG2316 Predicted hydrolase (HD superfamily); HDIG-domain-containing protein 305953 14294762 BPP43_01460 Brachyspira pilosicoli P43/6/78 HDIG-domain-containing protein YP_007233889.1 305381 R 1042417 CDS YP_007233890.1 431806992 14294763 306145..307590 1 NC_019908.1 COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl-tRNA synthetase 307590 14294763 BPP43_01465 Brachyspira pilosicoli P43/6/78 glutamyl-tRNA synthetase YP_007233890.1 306145 D 1042417 CDS YP_007233891.1 431806993 14294764 307605..307994 1 NC_019908.1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; response regulatory protein 307994 14294764 BPP43_01470 Brachyspira pilosicoli P43/6/78 response regulatory protein YP_007233891.1 307605 D 1042417 CDS YP_007233892.1 431806994 14294765 complement(308081..308728) 1 NC_019908.1 COG0036 Pentose-5-phosphate-3-epimerase; ribulose-phosphate 3-epimerase 308728 14294765 BPP43_01475 Brachyspira pilosicoli P43/6/78 ribulose-phosphate 3-epimerase YP_007233892.1 308081 R 1042417 CDS YP_007233893.1 431806995 14294766 complement(308754..309443) 1 NC_019908.1 COG0571 dsRNA-specific ribonuclease; ribonuclease III 309443 14294766 BPP43_01480 Brachyspira pilosicoli P43/6/78 ribonuclease III YP_007233893.1 308754 R 1042417 CDS YP_007233894.1 431806996 14294767 309588..311630 1 NC_019908.1 COG0536 Predicted GTPase; GTPase ObgE 311630 14294767 BPP43_01485 Brachyspira pilosicoli P43/6/78 GTPase ObgE YP_007233894.1 309588 D 1042417 CDS YP_007233895.1 431806997 14294768 complement(311688..311879) 1 NC_019908.1 hypothetical protein 311879 14294768 BPP43_01490 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233895.1 311688 R 1042417 CDS YP_007233896.1 431806998 14294769 312178..312939 1 NC_019908.1 hypothetical protein 312939 14294769 BPP43_01495 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233896.1 312178 D 1042417 CDS YP_007233897.1 431806999 14294770 313063..314154 1 NC_019908.1 sialidase 314154 14294770 BPP43_01500 Brachyspira pilosicoli P43/6/78 sialidase YP_007233897.1 313063 D 1042417 CDS YP_007233898.1 431807000 14294771 314193..314621 1 NC_019908.1 hypothetical protein 314621 14294771 BPP43_01505 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233898.1 314193 D 1042417 CDS YP_007233899.1 431807001 14294772 complement(314707..315774) 1 NC_019908.1 COG1363 Cellulase M and related proteins; cellulase M-like protein 315774 14294772 BPP43_01510 Brachyspira pilosicoli P43/6/78 cellulase M-like protein YP_007233899.1 314707 R 1042417 CDS YP_007233900.1 431807002 14294773 315916..317307 1 NC_019908.1 hypothetical protein 317307 14294773 BPP43_01515 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233900.1 315916 D 1042417 CDS YP_007233901.1 431807003 14294774 317433..318392 1 NC_019908.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; hypothetical protein 318392 14294774 BPP43_01520 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233901.1 317433 D 1042417 CDS YP_007233902.1 431807004 14294775 318483..319097 1 NC_019908.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 319097 14294775 BPP43_01525 Brachyspira pilosicoli P43/6/78 TetR family transcriptional regulator YP_007233902.1 318483 D 1042417 CDS YP_007233903.1 431807005 14294776 319118..319723 1 NC_019908.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 319723 14294776 BPP43_01530 Brachyspira pilosicoli P43/6/78 ABC transporter-like protein YP_007233903.1 319118 D 1042417 CDS YP_007233904.1 431807006 14294777 319666..319998 1 NC_019908.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 319998 14294777 BPP43_01535 Brachyspira pilosicoli P43/6/78 ABC transporter-like protein YP_007233904.1 319666 D 1042417 CDS YP_007233905.1 431807007 14294778 320022..320822 1 NC_019908.1 hypothetical protein 320822 14294778 BPP43_01540 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233905.1 320022 D 1042417 CDS YP_007233906.1 431807008 14294779 complement(321206..322438) 1 NC_019908.1 COG4992 Ornithine/acetylornithine aminotransferase; ornithine acetylornithine aminotransferase 322438 14294779 BPP43_01545 Brachyspira pilosicoli P43/6/78 ornithine acetylornithine aminotransferase YP_007233906.1 321206 R 1042417 CDS YP_007233907.1 431807009 14294780 complement(322470..323336) 1 NC_019908.1 COG0548 Acetylglutamate kinase; acetylglutamate kinase 323336 14294780 BPP43_01550 Brachyspira pilosicoli P43/6/78 acetylglutamate kinase YP_007233907.1 322470 R 1042417 CDS YP_007233908.1 431807010 14294781 complement(323375..324604) 1 NC_019908.1 COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase); bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 324604 14294781 BPP43_01555 Brachyspira pilosicoli P43/6/78 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_007233908.1 323375 R 1042417 CDS YP_007233909.1 431807011 14294782 complement(324661..325719) 1 NC_019908.1 COG0002 Acetylglutamate semialdehyde dehydrogenase; N-acetyl-gamma-glutamyl-phosphate reductase 325719 argC 14294782 argC Brachyspira pilosicoli P43/6/78 N-acetyl-gamma-glutamyl-phosphate reductase YP_007233909.1 324661 R 1042417 CDS YP_007233910.1 431807012 14294783 326163..327890 1 NC_019908.1 hypothetical protein 327890 14294783 BPP43_01565 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233910.1 326163 D 1042417 CDS YP_007233911.1 431807013 14294784 327964..329103 1 NC_019908.1 dynein heavy subunit 329103 14294784 BPP43_01570 Brachyspira pilosicoli P43/6/78 dynein heavy subunit YP_007233911.1 327964 D 1042417 CDS YP_007233912.1 431807014 14294785 complement(335533..337479) 1 NC_019908.1 COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; enoate reductase 337479 14294785 BPP43_01585 Brachyspira pilosicoli P43/6/78 enoate reductase YP_007233912.1 335533 R 1042417 CDS YP_007233913.1 431807015 14294786 complement(337668..338915) 1 NC_019908.1 COG0477 Permeases of the major facilitator superfamily; nitrate/nitrite transporter NarK 338915 14294786 BPP43_01590 Brachyspira pilosicoli P43/6/78 nitrate/nitrite transporter NarK YP_007233913.1 337668 R 1042417 CDS YP_007233914.1 431807016 14294787 339145..339681 1 NC_019908.1 COG1695 Predicted transcriptional regulators; PadR-like family transcriptional regulator 339681 14294787 BPP43_01595 Brachyspira pilosicoli P43/6/78 PadR-like family transcriptional regulator YP_007233914.1 339145 D 1042417 CDS YP_007233915.1 431807017 14294788 339793..341199 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 341199 14294788 BPP43_01600 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233915.1 339793 D 1042417 CDS YP_007233916.1 431807018 14294789 341282..341794 1 NC_019908.1 COG0293 23S rRNA methylase; ribosomal RNA methyltransferase RrmJ/FtsJ 341794 14294789 BPP43_01605 Brachyspira pilosicoli P43/6/78 ribosomal RNA methyltransferase RrmJ/FtsJ YP_007233916.1 341282 D 1042417 CDS YP_007233917.1 431807019 14294790 342508..342828 1 NC_019908.1 COG0640 Predicted transcriptional regulators; arsenical resistance operon repressor 342828 14294790 BPP43_01620 Brachyspira pilosicoli P43/6/78 arsenical resistance operon repressor YP_007233917.1 342508 D 1042417 CDS YP_007233918.1 431807020 14294791 343995..345422 1 NC_019908.1 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system diacetylchitobiose-specific transporter subunit EIIC 345422 14294791 BPP43_01635 Brachyspira pilosicoli P43/6/78 PTS system diacetylchitobiose-specific transporter subunit EIIC YP_007233918.1 343995 D 1042417 CDS YP_007233919.1 431807021 14294792 345445..346392 1 NC_019908.1 COG0294 Dihydropteroate synthase and related enzymes; hypothetical protein 346392 14294792 BPP43_01640 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233919.1 345445 D 1042417 CDS YP_007233920.1 431807022 14294793 346605..346802 1 NC_019908.1 COG0526 Thiol-disulfide isomerase and thioredoxins; hypothetical protein 346802 14294793 BPP43_01645 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233920.1 346605 D 1042417 CDS YP_007233921.1 431807023 14294794 347035..347184 1 NC_019908.1 COG0526 Thiol-disulfide isomerase and thioredoxins; redox-active disulfide protein 2 347184 14294794 BPP43_01650 Brachyspira pilosicoli P43/6/78 redox-active disulfide protein 2 YP_007233921.1 347035 D 1042417 CDS YP_007233922.1 431807024 14294795 347452..348903 1 NC_019908.1 COG0753 Catalase; catalase 348903 14294795 BPP43_01655 Brachyspira pilosicoli P43/6/78 catalase YP_007233922.1 347452 D 1042417 CDS YP_007233923.1 431807025 14294796 349141..351333 1 NC_019908.1 COG3345 Alpha-galactosidase; alpha-galactosidase 351333 14294796 BPP43_01660 Brachyspira pilosicoli P43/6/78 alpha-galactosidase YP_007233923.1 349141 D 1042417 CDS YP_007233924.1 431807026 14294797 351689..352495 1 NC_019908.1 COG0226 ABC-type phosphate transport system, periplasmic component; phosphate ABC transporter substrate-binding protein 352495 14294797 BPP43_01665 Brachyspira pilosicoli P43/6/78 phosphate ABC transporter substrate-binding protein YP_007233924.1 351689 D 1042417 CDS YP_007233925.1 431807027 14294798 352577..354367 1 NC_019908.1 COG0581 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease 354367 14294798 BPP43_01670 Brachyspira pilosicoli P43/6/78 phosphate ABC transporter permease YP_007233925.1 352577 D 1042417 CDS YP_007233926.1 431807028 14294799 354391..355188 1 NC_019908.1 COG1117 ABC-type phosphate transport system, ATPase component; phosphate ABC transporter ATP-binding protein 355188 14294799 BPP43_01675 Brachyspira pilosicoli P43/6/78 phosphate ABC transporter ATP-binding protein YP_007233926.1 354391 D 1042417 CDS YP_007233927.1 431807029 14294800 355231..355875 1 NC_019908.1 COG0704 Phosphate uptake regulator; phosphate uptake regulator PhoU 355875 14294800 BPP43_01680 Brachyspira pilosicoli P43/6/78 phosphate uptake regulator PhoU YP_007233927.1 355231 D 1042417 CDS YP_007233928.1 431807030 14294801 355998..356189 1 NC_019908.1 COG0227 Ribosomal protein L28; 50S ribosomal protein L28 356189 14294801 BPP43_01685 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L28 YP_007233928.1 355998 D 1042417 CDS YP_007233929.1 431807031 14294802 356189..357922 1 NC_019908.1 COG0761 Penicillin tolerance protein; hydroxymethylbutenyl pyrophosphate reductase 357922 14294802 BPP43_01690 Brachyspira pilosicoli P43/6/78 hydroxymethylbutenyl pyrophosphate reductase YP_007233929.1 356189 D 1042417 CDS YP_007233930.1 431807032 14294803 complement(357972..358439) 1 NC_019908.1 COG3330 Uncharacterized protein conserved in bacteria; hypothetical protein 358439 14294803 BPP43_01695 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233930.1 357972 R 1042417 CDS YP_007233931.1 431807033 14294804 358592..358918 1 NC_019908.1 hypothetical protein 358918 14294804 BPP43_01700 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233931.1 358592 D 1042417 CDS YP_007233932.1 431807034 14294805 359075..359611 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 359611 14294805 BPP43_01705 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233932.1 359075 D 1042417 CDS YP_007233933.1 431807035 14294806 359663..361363 1 NC_019908.1 hypothetical protein 361363 14294806 BPP43_01710 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233933.1 359663 D 1042417 CDS YP_007233934.1 431807036 14294807 361454..361882 1 NC_019908.1 COG0607 Rhodanese-related sulfurtransferase; rhodanese-like domain-containing protein 361882 14294807 BPP43_01715 Brachyspira pilosicoli P43/6/78 rhodanese-like domain-containing protein YP_007233934.1 361454 D 1042417 CDS YP_007233935.1 431807037 14294808 complement(361874..361987) 1 NC_019908.1 hypothetical protein 361987 14294808 BPP43_01720 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233935.1 361874 R 1042417 CDS YP_007233936.1 431807038 14294809 362121..364007 1 NC_019908.1 COG3593 Predicted ATP-dependent endonuclease of the OLD family; hypothetical protein 364007 14294809 BPP43_01725 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233936.1 362121 D 1042417 CDS YP_007233937.1 431807039 14294810 complement(364055..365257) 1 NC_019908.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aspartate aminotransferase 365257 14294810 BPP43_01730 Brachyspira pilosicoli P43/6/78 aspartate aminotransferase YP_007233937.1 364055 R 1042417 CDS YP_007233938.1 431807040 14294811 365422..367026 1 NC_019908.1 COG0405 Gamma-glutamyltransferase; gamma-glutamyltransferase 367026 14294811 BPP43_01735 Brachyspira pilosicoli P43/6/78 gamma-glutamyltransferase YP_007233938.1 365422 D 1042417 CDS YP_007233939.1 431807041 14294812 367138..367908 1 NC_019908.1 hypothetical protein 367908 14294812 BPP43_01740 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233939.1 367138 D 1042417 CDS YP_007233940.1 431807042 14294813 368049..368177 1 NC_019908.1 hypothetical protein 368177 14294813 BPP43_01745 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233940.1 368049 D 1042417 CDS YP_007233941.1 431807043 14294814 368292..368687 1 NC_019908.1 hypothetical protein 368687 14294814 BPP43_01750 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233941.1 368292 D 1042417 CDS YP_007233942.1 431807044 14294815 complement(371899..372984) 1 NC_019908.1 COG0505 Carbamoylphosphate synthase small subunit; carbamoyl phosphate synthase small subunit 372984 14294815 BPP43_01765 Brachyspira pilosicoli P43/6/78 carbamoyl phosphate synthase small subunit YP_007233942.1 371899 R 1042417 CDS YP_007233943.1 431807045 14294816 373894..373986 1 NC_019908.1 hypothetical protein 373986 14294816 BPP43_01780 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233943.1 373894 D 1042417 CDS YP_007233944.1 431807046 14294817 374669..375724 1 NC_019908.1 COG0498 Threonine synthase; threonine synthase 375724 14294817 BPP43_01785 Brachyspira pilosicoli P43/6/78 threonine synthase YP_007233944.1 374669 D 1042417 CDS YP_007233945.1 431807047 14294818 375728..376687 1 NC_019908.1 COG0083 Homoserine kinase; homoserine kinase 376687 14294818 BPP43_01790 Brachyspira pilosicoli P43/6/78 homoserine kinase YP_007233945.1 375728 D 1042417 CDS YP_007233946.1 431807048 14294819 complement(377122..378447) 1 NC_019908.1 COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; 6-phospho-alpha-glucosidase 378447 14294819 BPP43_01795 Brachyspira pilosicoli P43/6/78 6-phospho-alpha-glucosidase YP_007233946.1 377122 R 1042417 CDS YP_007233947.1 431807049 14294820 complement(378483..380066) 1 NC_019908.1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system arbutin-like transporter subunit IIC 380066 14294820 BPP43_01800 Brachyspira pilosicoli P43/6/78 PTS system arbutin-like transporter subunit IIC YP_007233947.1 378483 R 1042417 CDS YP_007233948.1 431807050 14294821 complement(380177..381532) 1 NC_019908.1 COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; alpha-galactosidase/6-phospho-beta-glucosidase 381532 14294821 BPP43_01805 Brachyspira pilosicoli P43/6/78 alpha-galactosidase/6-phospho-beta-glucosidase YP_007233948.1 380177 R 1042417 CDS YP_007233949.1 431807051 14294822 381783..382757 1 NC_019908.1 COG1609 Transcriptional regulators; periplasmic-binding protein/LacI transcriptional regulator 382757 14294822 BPP43_01810 Brachyspira pilosicoli P43/6/78 periplasmic-binding protein/LacI transcriptional regulator YP_007233949.1 381783 D 1042417 CDS YP_007233950.1 431807052 14294823 complement(382768..383433) 1 NC_019908.1 COG0132 Dethiobiotin synthetase; hypothetical protein 383433 14294823 BPP43_01815 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233950.1 382768 R 1042417 CDS YP_007233951.1 431807053 14294824 complement(383458..385575) 1 NC_019908.1 COG1449 Alpha-amylase/alpha-mannosidase; alpha-amylase 1 385575 14294824 BPP43_01820 Brachyspira pilosicoli P43/6/78 alpha-amylase 1 YP_007233951.1 383458 R 1042417 CDS YP_007233952.1 431807054 14294825 385844..386023 1 NC_019908.1 COG1251 NAD(P)H-nitrite reductase; Fer2/BFD BFD like 2Fe-2S--binding domain-containing protein 386023 14294825 BPP43_01825 Brachyspira pilosicoli P43/6/78 Fer2/BFD BFD like 2Fe-2S--binding domain-containing protein YP_007233952.1 385844 D 1042417 CDS YP_007233953.1 431807055 14294826 386048..386881 1 NC_019908.1 COG0822 NifU homolog involved in Fe-S cluster formation; NifU like N terminal domain-containing protein 386881 14294826 BPP43_01830 Brachyspira pilosicoli P43/6/78 NifU like N terminal domain-containing protein YP_007233953.1 386048 D 1042417 CDS YP_007233954.1 431807056 14294827 386885..388051 1 NC_019908.1 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; cysteine desulfurase 388051 14294827 BPP43_01835 Brachyspira pilosicoli P43/6/78 cysteine desulfurase YP_007233954.1 386885 D 1042417 CDS YP_007233955.1 431807057 14294828 388465..389376 1 NC_019908.1 COG0031 Cysteine synthase; cysteine synthase A 389376 14294828 BPP43_01840 Brachyspira pilosicoli P43/6/78 cysteine synthase A YP_007233955.1 388465 D 1042417 CDS YP_007233956.1 431807058 14294829 389389..390099 1 NC_019908.1 COG1045 Serine acetyltransferase; serine acetyltransferase 390099 14294829 BPP43_01845 Brachyspira pilosicoli P43/6/78 serine acetyltransferase YP_007233956.1 389389 D 1042417 CDS YP_007233957.1 431807059 14294830 complement(390908..391762) 1 NC_019908.1 COG0264 Translation elongation factor Ts; elongation factor Ts 391762 14294830 BPP43_01850 Brachyspira pilosicoli P43/6/78 elongation factor Ts YP_007233957.1 390908 R 1042417 CDS YP_007233958.1 431807060 14294831 complement(391794..392609) 1 NC_019908.1 COG0052 Ribosomal protein S2; 30S ribosomal protein S2 392609 14294831 BPP43_01855 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S2 YP_007233958.1 391794 R 1042417 CDS YP_007233959.1 431807061 14294832 394039..394236 1 NC_019908.1 hypothetical protein 394236 14294832 BPP43_01865 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233959.1 394039 D 1042417 CDS YP_007233960.1 431807062 14294833 394249..394395 1 NC_019908.1 hypothetical protein 394395 14294833 BPP43_01870 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233960.1 394249 D 1042417 CDS YP_007233961.1 431807063 14294834 complement(394829..395419) 1 NC_019908.1 COG1038 Pyruvate carboxylase; hypothetical protein 395419 14294834 BPP43_01880 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233961.1 394829 R 1042417 CDS YP_007233962.1 431807064 14294835 complement(395428..396087) 1 NC_019908.1 COG1611 Predicted Rossmann fold nucleotide-binding protein; Rossmann fold nucleotide-binding protein 396087 14294835 BPP43_01885 Brachyspira pilosicoli P43/6/78 Rossmann fold nucleotide-binding protein YP_007233962.1 395428 R 1042417 CDS YP_007233963.1 431807065 14294836 complement(396127..396438) 1 NC_019908.1 COG0393 Uncharacterized conserved protein; hypothetical protein 396438 14294836 BPP43_01890 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233963.1 396127 R 1042417 CDS YP_007233964.1 431807066 14293233 396597..397205 1 NC_019908.1 hypothetical protein 397205 14293233 BPP43_01895 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233964.1 396597 D 1042417 CDS YP_007233965.1 431807067 14293234 397221..398225 1 NC_019908.1 COG0530 Ca2+/Na+ antiporter; Na+/Ca+ exchange protein 398225 14293234 BPP43_01900 Brachyspira pilosicoli P43/6/78 Na+/Ca+ exchange protein YP_007233965.1 397221 D 1042417 CDS YP_007233966.1 431807068 14293235 398729..399925 1 NC_019908.1 COG4591 ABC-type transport system, involved in lipoprotein release, permease component; lipoprotein 399925 14293235 BPP43_01905 Brachyspira pilosicoli P43/6/78 lipoprotein YP_007233966.1 398729 D 1042417 CDS YP_007233967.1 431807069 14293236 399918..400628 1 NC_019908.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; lipoprotein 400628 14293236 BPP43_01910 Brachyspira pilosicoli P43/6/78 lipoprotein YP_007233967.1 399918 D 1042417 CDS YP_007233968.1 431807070 14293237 400707..401213 1 NC_019908.1 hypothetical protein 401213 14293237 BPP43_01915 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233968.1 400707 D 1042417 CDS YP_007233969.1 431807071 14293238 complement(401188..401787) 1 NC_019908.1 hypothetical protein 401787 14293238 BPP43_01920 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233969.1 401188 R 1042417 CDS YP_007233970.1 431807072 14293239 complement(401774..403243) 1 NC_019908.1 COG1462 Uncharacterized protein involved in formation of curli polymers; curli production assembly transport component CsgG 403243 14293239 BPP43_01925 Brachyspira pilosicoli P43/6/78 curli production assembly transport component CsgG YP_007233970.1 401774 R 1042417 CDS YP_007233971.1 431807073 14293240 403527..406463 1 NC_019908.1 COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); preprotein translocase subunit SecA 406463 14293240 BPP43_01930 Brachyspira pilosicoli P43/6/78 preprotein translocase subunit SecA YP_007233971.1 403527 D 1042417 CDS YP_007233972.1 431807074 14293241 406506..407387 1 NC_019908.1 hypothetical protein 407387 14293241 BPP43_01935 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233972.1 406506 D 1042417 CDS YP_007233973.1 431807075 14293242 complement(407377..408288) 1 NC_019908.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; transmembrane protein 408288 14293242 BPP43_01940 Brachyspira pilosicoli P43/6/78 transmembrane protein YP_007233973.1 407377 R 1042417 CDS YP_007233974.1 431807076 14293243 complement(408281..409165) 1 NC_019908.1 COG1354 Uncharacterized conserved protein; segregation and condensation protein A ScpA 409165 14293243 BPP43_01945 Brachyspira pilosicoli P43/6/78 segregation and condensation protein A ScpA YP_007233974.1 408281 R 1042417 CDS YP_007233975.1 431807077 14293244 complement(409212..409874) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 409874 14293244 BPP43_01950 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007233975.1 409212 R 1042417 CDS YP_007233976.1 431807078 14293245 complement(409911..410066) 1 NC_019908.1 hypothetical protein 410066 14293245 BPP43_01955 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233976.1 409911 R 1042417 CDS YP_007233977.1 431807079 14293246 complement(410170..411531) 1 NC_019908.1 COG0655 Multimeric flavodoxin WrbA; hypothetical protein 411531 14293246 BPP43_01960 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233977.1 410170 R 1042417 CDS YP_007233978.1 431807080 14293247 complement(411590..412675) 1 NC_019908.1 hypothetical protein 412675 14293247 BPP43_01965 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233978.1 411590 R 1042417 CDS YP_007233979.1 431807081 14293248 412871..415096 1 NC_019908.1 COG3250 Beta-galactosidase/beta-glucuronidase; beta-D-galactosidase 415096 14293248 BPP43_01970 Brachyspira pilosicoli P43/6/78 beta-D-galactosidase YP_007233979.1 412871 D 1042417 CDS YP_007233980.1 431807082 14293249 415130..415969 1 NC_019908.1 COG0253 Diaminopimelate epimerase; diaminopimelate epimerase 415969 14293249 BPP43_01975 Brachyspira pilosicoli P43/6/78 diaminopimelate epimerase YP_007233980.1 415130 D 1042417 CDS YP_007233981.1 431807083 14293250 complement(415975..416160) 1 NC_019908.1 COG1251 NAD(P)H-nitrite reductase; Fer2 BFD, BFD-like [2Fe-2S]-binding domain-containing protein 416160 14293250 BPP43_01980 Brachyspira pilosicoli P43/6/78 Fer2 BFD, BFD-like [2Fe-2S]-binding domain-containing protein YP_007233981.1 415975 R 1042417 CDS YP_007233982.1 431807084 14293251 416221..416331 1 NC_019908.1 hypothetical protein 416331 14293251 BPP43_01985 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233982.1 416221 D 1042417 CDS YP_007233983.1 431807085 14293252 416328..416561 1 NC_019908.1 hypothetical protein 416561 14293252 BPP43_01990 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233983.1 416328 D 1042417 CDS YP_007233984.1 431807086 14293253 416564..416935 1 NC_019908.1 hypothetical protein 416935 14293253 BPP43_01995 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233984.1 416564 D 1042417 CDS YP_007233985.1 431807087 14293254 complement(417064..417936) 1 NC_019908.1 COG1344 Flagellin and related hook-associated proteins; flagellar protein FlaB2 417936 14293254 BPP43_02000 Brachyspira pilosicoli P43/6/78 flagellar protein FlaB2 YP_007233985.1 417064 R 1042417 CDS YP_007233986.1 431807088 14293255 418212..420350 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 420350 14293255 BPP43_02005 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007233986.1 418212 D 1042417 CDS YP_007233987.1 431807089 14293256 420534..422348 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis sensory transducer 422348 14293256 BPP43_02010 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis sensory transducer YP_007233987.1 420534 D 1042417 CDS YP_007233988.1 431807090 14293257 complement(422418..423074) 1 NC_019908.1 hypothetical protein 423074 14293257 BPP43_02015 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233988.1 422418 R 1042417 CDS YP_007233989.1 431807091 14293258 complement(423169..424413) 1 NC_019908.1 hypothetical protein 424413 14293258 BPP43_02020 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233989.1 423169 R 1042417 CDS YP_007233990.1 431807092 14293259 424674..427238 1 NC_019908.1 COG0058 Glucan phosphorylase; alpha glucan phosphorylase 427238 14293259 BPP43_02025 Brachyspira pilosicoli P43/6/78 alpha glucan phosphorylase YP_007233990.1 424674 D 1042417 CDS YP_007233991.1 431807093 14293260 427485..428183 1 NC_019908.1 COG1811 Uncharacterized membrane protein, possible Na+ channel or pump; hypothetical protein 428183 14293260 BPP43_02030 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233991.1 427485 D 1042417 CDS YP_007233992.1 431807094 14293261 428222..429337 1 NC_019908.1 hypothetical protein 429337 14293261 BPP43_02035 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233992.1 428222 D 1042417 CDS YP_007233993.1 431807095 14293262 complement(429580..432597) 1 NC_019908.1 COG0553 Superfamily II DNA/RNA helicases, SNF2 family; HepA Superfamily II D R helicase 432597 14293262 BPP43_02040 Brachyspira pilosicoli P43/6/78 HepA Superfamily II D R helicase YP_007233993.1 429580 R 1042417 CDS YP_007233994.1 431807096 14293263 432864..433166 1 NC_019908.1 hypothetical protein 433166 14293263 BPP43_02045 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233994.1 432864 D 1042417 CDS YP_007233995.1 431807097 14293264 433190..434449 1 NC_019908.1 COG1729 Uncharacterized protein conserved in bacteria; hypothetical protein 434449 14293264 BPP43_02050 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233995.1 433190 D 1042417 CDS YP_007233996.1 431807098 14293265 434587..435324 1 NC_019908.1 hypothetical protein 435324 14293265 BPP43_02055 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233996.1 434587 D 1042417 CDS YP_007233997.1 431807099 14293266 435354..435860 1 NC_019908.1 COG4731 Uncharacterized protein conserved in bacteria; hypothetical protein 435860 14293266 BPP43_02060 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007233997.1 435354 D 1042417 CDS YP_007233998.1 431807100 14293267 complement(437568..438284) 1 NC_019908.1 COG2071 Predicted glutamine amidotransferases; glutamine amidotransferase 438284 14293267 BPP43_02075 Brachyspira pilosicoli P43/6/78 glutamine amidotransferase YP_007233998.1 437568 R 1042417 CDS YP_007233999.1 431807101 14293268 438531..439889 1 NC_019908.1 COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; NADH oxidase 439889 14293268 BPP43_02080 Brachyspira pilosicoli P43/6/78 NADH oxidase YP_007233999.1 438531 D 1042417 CDS YP_007234000.1 431807102 14293269 440308..442119 1 NC_019908.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; hypothetical protein 442119 14293269 BPP43_02085 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234000.1 440308 D 1042417 CDS YP_007234001.1 431807103 14293270 442161..443747 1 NC_019908.1 COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold; amidohydrolase 3 443747 14293270 BPP43_02090 Brachyspira pilosicoli P43/6/78 amidohydrolase 3 YP_007234001.1 442161 D 1042417 CDS YP_007234002.1 431807104 14293271 443793..444809 1 NC_019908.1 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 444809 14293271 BPP43_02095 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234002.1 443793 D 1042417 CDS YP_007234003.1 431807105 14293272 444826..445701 1 NC_019908.1 COG0457 FOG: TPR repeat; aerotolerance-like membrane protein 445701 14293272 BPP43_02100 Brachyspira pilosicoli P43/6/78 aerotolerance-like membrane protein YP_007234003.1 444826 D 1042417 CDS YP_007234004.1 431807106 14293273 445685..447364 1 NC_019908.1 aerotolerance-like exported protein 447364 14293273 BPP43_02105 Brachyspira pilosicoli P43/6/78 aerotolerance-like exported protein YP_007234004.1 445685 D 1042417 CDS YP_007234005.1 431807107 14293274 447397..448050 1 NC_019908.1 COG0457 FOG: TPR repeat; aerotolerance-like exported protein 448050 14293274 BPP43_02110 Brachyspira pilosicoli P43/6/78 aerotolerance-like exported protein YP_007234005.1 447397 D 1042417 CDS YP_007234006.1 431807108 14293275 complement(448065..449741) 1 NC_019908.1 COG0661 Predicted unusual protein kinase; protein kinase 449741 14293275 BPP43_02115 Brachyspira pilosicoli P43/6/78 protein kinase YP_007234006.1 448065 R 1042417 CDS YP_007234007.1 431807109 14293276 complement(449782..450090) 1 NC_019908.1 hypothetical protein 450090 14293276 BPP43_02120 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234007.1 449782 R 1042417 CDS YP_007234008.1 431807110 14293277 450496..452169 1 NC_019908.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase large subunit 452169 14293277 BPP43_02125 Brachyspira pilosicoli P43/6/78 acetolactate synthase large subunit YP_007234008.1 450496 D 1042417 CDS YP_007234009.1 431807111 14293278 452189..452716 1 NC_019908.1 COG0440 Acetolactate synthase, small (regulatory) subunit; hypothetical protein 452716 14293278 BPP43_02130 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234009.1 452189 D 1042417 CDS YP_007234010.1 431807112 14293279 452771..453766 1 NC_019908.1 COG0059 Ketol-acid reductoisomerase; ketol acid reductoisomerase 453766 14293279 BPP43_02135 Brachyspira pilosicoli P43/6/78 ketol acid reductoisomerase YP_007234010.1 452771 D 1042417 CDS YP_007234011.1 431807113 14293280 454064..455497 1 NC_019908.1 COG0119 Isopropylmalate/homocitrate/citramalate synthases; 2-isopropylmalate synthase 455497 14293280 BPP43_02140 Brachyspira pilosicoli P43/6/78 2-isopropylmalate synthase YP_007234011.1 454064 D 1042417 CDS YP_007234012.1 431807114 14293281 455601..456848 1 NC_019908.1 COG0065 3-isopropylmalate dehydratase large subunit; 3-isopropylmalate dehydratase large subunit 456848 14293281 BPP43_02145 Brachyspira pilosicoli P43/6/78 3-isopropylmalate dehydratase large subunit YP_007234012.1 455601 D 1042417 CDS YP_007234013.1 431807115 14293282 457136..457618 1 NC_019908.1 COG0066 3-isopropylmalate dehydratase small subunit; 3-isopropylmalate dehydratase small subunit 457618 14293282 BPP43_02150 Brachyspira pilosicoli P43/6/78 3-isopropylmalate dehydratase small subunit YP_007234013.1 457136 D 1042417 CDS YP_007234014.1 431807116 14293283 457637..458725 1 NC_019908.1 COG0473 Isocitrate/isopropylmalate dehydrogenase; 3-isopropylmalate dehydrogenase 458725 14293283 BPP43_02155 Brachyspira pilosicoli P43/6/78 3-isopropylmalate dehydrogenase YP_007234014.1 457637 D 1042417 CDS YP_007234015.1 431807117 14293284 458864..459100 1 NC_019908.1 hypothetical protein 459100 14293284 BPP43_02160 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234015.1 458864 D 1042417 CDS YP_007234016.1 431807118 14293285 459093..459806 1 NC_019908.1 COG1496 Uncharacterized conserved protein; hypothetical protein 459806 14293285 BPP43_02165 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234016.1 459093 D 1042417 CDS YP_007234017.1 431807119 14293286 460789..461238 1 NC_019908.1 COG0698 Ribose 5-phosphate isomerase RpiB; ribose-5-phosphate isomerase B 461238 14293286 BPP43_02180 Brachyspira pilosicoli P43/6/78 ribose-5-phosphate isomerase B YP_007234017.1 460789 D 1042417 CDS YP_007234018.1 431807120 14293287 complement(461306..462895) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 462895 14293287 BPP43_02185 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234018.1 461306 R 1042417 CDS YP_007234019.1 431807121 14293288 463281..464390 1 NC_019908.1 COG1672 Predicted ATPase (AAA+ superfamily); hypothetical protein 464390 14293288 BPP43_02190 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234019.1 463281 D 1042417 CDS YP_007234020.1 431807122 14293289 complement(464665..466374) 1 NC_019908.1 COG4232 Thiol:disulfide interchange protein; thiol disulfide interchange protein 466374 14293289 BPP43_02195 Brachyspira pilosicoli P43/6/78 thiol disulfide interchange protein YP_007234020.1 464665 R 1042417 CDS YP_007234021.1 431807123 14293290 complement(466448..466861) 1 NC_019908.1 COG0607 Rhodanese-related sulfurtransferase; rhodanese-like protein 466861 14293290 BPP43_02200 Brachyspira pilosicoli P43/6/78 rhodanese-like protein YP_007234021.1 466448 R 1042417 CDS YP_007234022.1 431807124 14293291 467091..467189 1 NC_019908.1 hypothetical protein 467189 14293291 BPP43_02205 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234022.1 467091 D 1042417 CDS YP_007234023.1 431807125 14293292 467281..468870 1 NC_019908.1 COG0286 Type I restriction-modification system methyltransferase subunit; type-I restriction-modification system HsdM 468870 14293292 BPP43_02210 Brachyspira pilosicoli P43/6/78 type-I restriction-modification system HsdM YP_007234023.1 467281 D 1042417 CDS YP_007234024.1 431807126 14293293 468991..470013 1 NC_019908.1 COG0732 Restriction endonuclease S subunits; restriction endonuclease type I S subunit 470013 14293293 BPP43_02215 Brachyspira pilosicoli P43/6/78 restriction endonuclease type I S subunit YP_007234024.1 468991 D 1042417 CDS YP_007234025.1 431807127 14293294 473308..473862 1 NC_019908.1 COG1843 Flagellar hook capping protein; hypothetical protein 473862 14293294 BPP43_02230 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234025.1 473308 D 1042417 CDS YP_007234026.1 431807128 14293295 473942..475810 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; hypothetical protein 475810 14293295 BPP43_02235 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234026.1 473942 D 1042417 CDS YP_007234027.1 431807129 14293296 476077..477354 1 NC_019908.1 hypothetical protein 477354 14293296 BPP43_02240 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234027.1 476077 D 1042417 CDS YP_007234028.1 431807130 14293297 478614..479054 1 NC_019908.1 COG1158 Transcription termination factor; hypothetical protein 479054 14293297 BPP43_02255 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234028.1 478614 D 1042417 CDS YP_007234029.1 431807131 14293298 479267..480682 1 NC_019908.1 hypothetical protein 480682 14293298 BPP43_02260 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234029.1 479267 D 1042417 CDS YP_007234030.1 431807132 14293299 480771..481433 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin 2,3/unc44-like protein 481433 14293299 BPP43_02265 Brachyspira pilosicoli P43/6/78 ankyrin 2,3/unc44-like protein YP_007234030.1 480771 D 1042417 CDS YP_007234031.1 431807133 14293300 481491..482021 1 NC_019908.1 hypothetical protein 482021 14293300 BPP43_02270 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234031.1 481491 D 1042417 CDS YP_007234032.1 431807134 14293301 482065..482514 1 NC_019908.1 COG2258 Uncharacterized protein conserved in bacteria; molybdenum cofactor sulfurase 482514 14293301 BPP43_02275 Brachyspira pilosicoli P43/6/78 molybdenum cofactor sulfurase YP_007234032.1 482065 D 1042417 CDS YP_007234033.1 431807135 14293302 482486..482956 1 NC_019908.1 COG0521 Molybdopterin biosynthesis enzymes; molybdenum cofactor synthesis domain-containing protein 482956 14293302 BPP43_02280 Brachyspira pilosicoli P43/6/78 molybdenum cofactor synthesis domain-containing protein YP_007234033.1 482486 D 1042417 CDS YP_007234034.1 431807136 14293303 482993..483772 1 NC_019908.1 COG0725 ABC-type molybdate transport system, periplasmic component; molybdate ABC transporter substrate-binding protein 483772 14293303 BPP43_02285 Brachyspira pilosicoli P43/6/78 molybdate ABC transporter substrate-binding protein YP_007234034.1 482993 D 1042417 CDS YP_007234035.1 431807137 14293304 483935..484456 1 NC_019908.1 COG4149 ABC-type molybdate transport system, permease component; molybdenum transport system permease 484456 14293304 BPP43_02290 Brachyspira pilosicoli P43/6/78 molybdenum transport system permease YP_007234035.1 483935 D 1042417 CDS YP_007234036.1 431807138 14293305 484481..485515 1 NC_019908.1 COG1118 ABC-type sulfate/molybdate transport systems, ATPase component; transport protein 485515 14293305 BPP43_02295 Brachyspira pilosicoli P43/6/78 transport protein YP_007234036.1 484481 D 1042417 CDS YP_007234037.1 431807139 14293306 485551..486759 1 NC_019908.1 COG0303 Molybdopterin biosynthesis enzyme; molybdenum cofactor synthesis domain-containing protein 486759 14293306 BPP43_02300 Brachyspira pilosicoli P43/6/78 molybdenum cofactor synthesis domain-containing protein YP_007234037.1 485551 D 1042417 CDS YP_007234038.1 431807140 14293307 486743..487540 1 NC_019908.1 COG2896 Molybdenum cofactor biosynthesis enzyme; molybdenum cofactor biosynthesis protein A 487540 14293307 BPP43_02305 Brachyspira pilosicoli P43/6/78 molybdenum cofactor biosynthesis protein A YP_007234038.1 486743 D 1042417 CDS YP_007234039.1 431807141 14293308 487542..487994 1 NC_019908.1 COG0315 Molybdenum cofactor biosynthesis enzyme; molybdenum cofactor biosynthesis protein C 487994 14293308 BPP43_02310 Brachyspira pilosicoli P43/6/78 molybdenum cofactor biosynthesis protein C YP_007234039.1 487542 D 1042417 CDS YP_007234040.1 431807142 14293309 complement(488033..488731) 1 NC_019908.1 hypothetical protein 488731 14293309 BPP43_02315 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234040.1 488033 R 1042417 CDS YP_007234041.1 431807143 14293310 complement(488814..489416) 1 NC_019908.1 hypothetical protein 489416 14293310 BPP43_02320 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234041.1 488814 R 1042417 CDS YP_007234042.1 431807144 14293311 complement(489420..490535) 1 NC_019908.1 COG0006 Xaa-Pro aminopeptidase; Pro aminopeptidase 490535 14293311 BPP43_02325 Brachyspira pilosicoli P43/6/78 Pro aminopeptidase YP_007234042.1 489420 R 1042417 CDS YP_007234043.1 431807145 14293312 complement(490612..492345) 1 NC_019908.1 COG2604 Uncharacterized protein conserved in bacteria; hypothetical protein 492345 14293312 BPP43_02330 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234043.1 490612 R 1042417 CDS YP_007234044.1 431807146 14293313 492471..492893 1 NC_019908.1 COG0784 FOG: CheY-like receiver; chemotaxis response regulator CheY 492893 14293313 BPP43_02335 Brachyspira pilosicoli P43/6/78 chemotaxis response regulator CheY YP_007234044.1 492471 D 1042417 CDS YP_007234045.1 431807147 14293314 complement(492904..493110) 1 NC_019908.1 hypothetical protein 493110 14293314 BPP43_02340 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234045.1 492904 R 1042417 CDS YP_007234046.1 431807148 14293315 complement(493161..493727) 1 NC_019908.1 hypothetical protein 493727 14293315 BPP43_02345 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234046.1 493161 R 1042417 CDS YP_007234047.1 431807149 14293316 complement(493810..494109) 1 NC_019908.1 hypothetical protein 494109 14293316 BPP43_02350 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234047.1 493810 R 1042417 CDS YP_007234048.1 431807150 14293317 494280..495518 1 NC_019908.1 COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase 495518 14293317 BPP43_02355 Brachyspira pilosicoli P43/6/78 diaminopimelate decarboxylase YP_007234048.1 494280 D 1042417 CDS YP_007234049.1 431807151 14293318 complement(495656..496060) 1 NC_019908.1 COG1321 Mn-dependent transcriptional regulator; iron-dependent repressor 496060 14293318 BPP43_02360 Brachyspira pilosicoli P43/6/78 iron-dependent repressor YP_007234049.1 495656 R 1042417 CDS YP_007234050.1 431807152 14293321 496477..496926 1 NC_019908.1 COG1778 Low specificity phosphatase (HAD superfamily); 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 496926 14293321 BPP43_02365 Brachyspira pilosicoli P43/6/78 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_007234050.1 496477 D 1042417 CDS YP_007234051.1 431807153 14293322 497004..497570 1 NC_019908.1 hypothetical protein 497570 14293322 BPP43_02370 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234051.1 497004 D 1042417 CDS YP_007234052.1 431807154 14293323 497557..498900 1 NC_019908.1 COG1934 Uncharacterized protein conserved in bacteria; hypothetical protein 498900 14293323 BPP43_02375 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234052.1 497557 D 1042417 CDS YP_007234053.1 431807155 14293324 complement(499929..502163) 1 NC_019908.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic transglycosylase catalytic domain-containing protein 502163 14293324 BPP43_02390 Brachyspira pilosicoli P43/6/78 lytic transglycosylase catalytic domain-containing protein YP_007234053.1 499929 R 1042417 CDS YP_007234054.1 431807156 14293325 502406..503386 1 NC_019908.1 COG1609 Transcriptional regulators; transcriptional regulator 503386 14293325 BPP43_02395 Brachyspira pilosicoli P43/6/78 transcriptional regulator YP_007234054.1 502406 D 1042417 CDS YP_007234055.1 431807157 14293326 complement(503475..504623) 1 NC_019908.1 COG1454 Alcohol dehydrogenase, class IV; L-1,2-propanediol oxidoreductase 504623 14293326 BPP43_02400 Brachyspira pilosicoli P43/6/78 L-1,2-propanediol oxidoreductase YP_007234055.1 503475 R 1042417 CDS YP_007234056.1 431807158 14293327 complement(504674..505384) 1 NC_019908.1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; ribulose-5-phosphate 4-epimerase-like epimerase/aldolase 505384 14293327 BPP43_02405 Brachyspira pilosicoli P43/6/78 ribulose-5-phosphate 4-epimerase-like epimerase/aldolase YP_007234056.1 504674 R 1042417 CDS YP_007234057.1 431807159 14293328 complement(505421..506830) 1 NC_019908.1 COG1070 Sugar (pentulose and hexulose) kinases; carbohydrate kinase FGGY 506830 14293328 BPP43_02410 Brachyspira pilosicoli P43/6/78 carbohydrate kinase FGGY YP_007234057.1 505421 R 1042417 CDS YP_007234058.1 431807160 14293329 507072..508568 1 NC_019908.1 COG1129 ABC-type sugar transport system, ATPase component; hypothetical protein 508568 14293329 BPP43_02415 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234058.1 507072 D 1042417 CDS YP_007234059.1 431807161 14293330 508610..509827 1 NC_019908.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar ABC transporter permease 509827 14293330 BPP43_02420 Brachyspira pilosicoli P43/6/78 sugar ABC transporter permease YP_007234059.1 508610 D 1042417 CDS YP_007234060.1 431807162 14293331 509876..510898 1 NC_019908.1 COG1879 ABC-type sugar transport system, periplasmic component; sugar ABC transporter substrate-binding protein 510898 14293331 BPP43_02425 Brachyspira pilosicoli P43/6/78 sugar ABC transporter substrate-binding protein YP_007234060.1 509876 D 1042417 CDS YP_007234061.1 431807163 14293332 510935..512716 1 NC_019908.1 COG2407 L-fucose isomerase and related proteins; L-fucose isomerase 512716 fucI 14293332 fucI Brachyspira pilosicoli P43/6/78 L-fucose isomerase YP_007234061.1 510935 D 1042417 CDS YP_007234062.1 431807164 14293333 512806..513240 1 NC_019908.1 COG4154 Fucose dissimilation pathway protein FucU; transporter 513240 14293333 BPP43_02435 Brachyspira pilosicoli P43/6/78 transporter YP_007234062.1 512806 D 1042417 CDS YP_007234063.1 431807165 14293334 513516..516164 1 NC_019908.1 COG0474 Cation transport ATPase; calcium-transporting ATPase 516164 14293334 BPP43_02440 Brachyspira pilosicoli P43/6/78 calcium-transporting ATPase YP_007234063.1 513516 D 1042417 CDS YP_007234064.1 431807166 14293335 516344..517522 1 NC_019908.1 COG0153 Galactokinase; galactokinase 517522 14293335 BPP43_02445 Brachyspira pilosicoli P43/6/78 galactokinase YP_007234064.1 516344 D 1042417 CDS YP_007234065.1 431807167 14293336 518753..520381 1 NC_019908.1 COG3225 ABC-type uncharacterized transport system involved in gliding motility, auxiliary component; ABC transporter-like protein 520381 14293336 BPP43_02460 Brachyspira pilosicoli P43/6/78 ABC transporter-like protein YP_007234065.1 518753 D 1042417 CDS YP_007234066.1 431807168 14293337 520411..521685 1 NC_019908.1 hypothetical protein 521685 14293337 BPP43_02465 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234066.1 520411 D 1042417 CDS YP_007234067.1 431807169 14293338 complement(521698..522396) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 522396 14293338 BPP43_02470 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234067.1 521698 R 1042417 CDS YP_007234068.1 431807170 14293339 522579..523778 1 NC_019908.1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; cAMP-binding protein 523778 14293339 BPP43_02475 Brachyspira pilosicoli P43/6/78 cAMP-binding protein YP_007234068.1 522579 D 1042417 CDS YP_007234069.1 431807171 14293340 complement(523780..524502) 1 NC_019908.1 COG1189 Predicted rRNA methylase; hemolysin A 524502 14293340 BPP43_02480 Brachyspira pilosicoli P43/6/78 hemolysin A YP_007234069.1 523780 R 1042417 CDS YP_007234070.1 431807172 14293341 complement(524511..526019) 1 NC_019908.1 hypothetical protein 526019 14293341 BPP43_02485 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234070.1 524511 R 1042417 CDS YP_007234071.1 431807173 14293342 526204..526827 1 NC_019908.1 COG0716 Flavodoxins; hypothetical protein 526827 14293342 BPP43_02490 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234071.1 526204 D 1042417 CDS YP_007234072.1 431807174 14293343 526919..527848 1 NC_019908.1 COG2267 Lysophospholipase; lysophospholipase 527848 14293343 BPP43_02495 Brachyspira pilosicoli P43/6/78 lysophospholipase YP_007234072.1 526919 D 1042417 CDS YP_007234073.1 431807175 14293344 527876..528499 1 NC_019908.1 COG0279 Phosphoheptose isomerase; phosphoheptose isomerase 528499 14293344 BPP43_02500 Brachyspira pilosicoli P43/6/78 phosphoheptose isomerase YP_007234073.1 527876 D 1042417 CDS YP_007234074.1 431807176 14293345 528518..529546 1 NC_019908.1 COG0859 ADP-heptose:LPS heptosyltransferase; lipopolysaccharide heptosyltransferase II 529546 14293345 BPP43_02505 Brachyspira pilosicoli P43/6/78 lipopolysaccharide heptosyltransferase II YP_007234074.1 528518 D 1042417 CDS YP_007234075.1 431807177 14293346 complement(529552..529815) 1 NC_019908.1 hypothetical protein 529815 14293346 BPP43_02510 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234075.1 529552 R 1042417 CDS YP_007234076.1 431807178 14293347 complement(529799..532354) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 532354 14293347 BPP43_02515 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234076.1 529799 R 1042417 CDS YP_007234077.1 431807179 14293348 complement(532407..532826) 1 NC_019908.1 hypothetical protein 532826 14293348 BPP43_02520 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234077.1 532407 R 1042417 CDS YP_007234078.1 431807180 14293349 complement(532966..534627) 1 NC_019908.1 COG1966 Carbon starvation protein, predicted membrane protein; carbon starvation protein CstA 534627 14293349 BPP43_02525 Brachyspira pilosicoli P43/6/78 carbon starvation protein CstA YP_007234078.1 532966 R 1042417 CDS YP_007234079.1 431807181 14293350 complement(534652..535176) 1 NC_019908.1 COG0366 Glycosidases; hypothetical protein 535176 14293350 BPP43_02530 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234079.1 534652 R 1042417 CDS YP_007234080.1 431807182 14293351 complement(535321..536211) 1 NC_019908.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; lipoprotein 536211 14293351 BPP43_02535 Brachyspira pilosicoli P43/6/78 lipoprotein YP_007234080.1 535321 R 1042417 CDS YP_007234081.1 431807183 14293352 complement(536219..536800) 1 NC_019908.1 COG1057 Nicotinic acid mononucleotide adenylyltransferase; nicotinate (nicotinamide) nucleotide adenylyltransferase 536800 14293352 BPP43_02540 Brachyspira pilosicoli P43/6/78 nicotinate (nicotinamide) nucleotide adenylyltransferase YP_007234081.1 536219 R 1042417 CDS YP_007234082.1 431807184 14293353 complement(536904..538115) 1 NC_019908.1 COG0044 Dihydroorotase and related cyclic amidohydrolases; dihydroorotase 538115 14293353 BPP43_02545 Brachyspira pilosicoli P43/6/78 dihydroorotase YP_007234082.1 536904 R 1042417 CDS YP_007234083.1 431807185 14293354 complement(538112..539191) 1 NC_019908.1 COG0540 Aspartate carbamoyltransferase, catalytic chain; aspartate carbamoyltransferase catalytic subunit 539191 14293354 BPP43_02550 Brachyspira pilosicoli P43/6/78 aspartate carbamoyltransferase catalytic subunit YP_007234083.1 538112 R 1042417 CDS YP_007234084.1 431807186 14293355 539706..540098 1 NC_019908.1 hypothetical protein 540098 14293355 BPP43_02555 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234084.1 539706 D 1042417 CDS YP_007234085.1 431807187 14293356 540340..541707 1 NC_019908.1 COG1109 Phosphomannomutase; phosphomannomutase 541707 14293356 BPP43_02560 Brachyspira pilosicoli P43/6/78 phosphomannomutase YP_007234085.1 540340 D 1042417 CDS YP_007234086.1 431807188 14293357 542628..543038 1 NC_019908.1 COG0848 Biopolymer transport protein; biopolymer transport protein ExbD/TolR 543038 14293357 BPP43_02575 Brachyspira pilosicoli P43/6/78 biopolymer transport protein ExbD/TolR YP_007234086.1 542628 D 1042417 CDS YP_007234087.1 431807189 14293358 543075..543647 1 NC_019908.1 COG0425 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein 543647 14293358 BPP43_02580 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234087.1 543075 D 1042417 CDS YP_007234088.1 431807190 14293359 543654..544769 1 NC_019908.1 COG0520 Selenocysteine lyase; class V aminotransferase 544769 14293359 BPP43_02585 Brachyspira pilosicoli P43/6/78 class V aminotransferase YP_007234088.1 543654 D 1042417 CDS YP_007234089.1 431807191 14293360 544782..545000 1 NC_019908.1 hypothetical protein 545000 14293360 BPP43_02590 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234089.1 544782 D 1042417 CDS YP_007234090.1 431807192 14293361 complement(545263..546453) 1 NC_019908.1 COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; Na(+)/H(+) antiporter 546453 14293361 BPP43_02595 Brachyspira pilosicoli P43/6/78 Na(+)/H(+) antiporter YP_007234090.1 545263 R 1042417 CDS YP_007234091.1 431807193 14293362 547137..547865 1 NC_019908.1 hypothetical protein 547865 14293362 BPP43_02600 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234091.1 547137 D 1042417 CDS YP_007234092.1 431807194 14293363 548083..550191 1 NC_019908.1 hypothetical protein 550191 14293363 BPP43_02605 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234092.1 548083 D 1042417 CDS YP_007234093.1 431807195 14293364 550201..552939 1 NC_019908.1 RNA polymerase sigma-70 factor 552939 14293364 BPP43_02610 Brachyspira pilosicoli P43/6/78 RNA polymerase sigma-70 factor YP_007234093.1 550201 D 1042417 CDS YP_007234094.1 431807196 14293365 552973..553734 1 NC_019908.1 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; glucosamine 6 phosphate isomerase 553734 14293365 BPP43_02615 Brachyspira pilosicoli P43/6/78 glucosamine 6 phosphate isomerase YP_007234094.1 552973 D 1042417 CDS YP_007234095.1 431807197 14293366 553762..555726 1 NC_019908.1 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; N-acetylglucosamine 6 phosphate deacetylase 555726 14293366 BPP43_02620 Brachyspira pilosicoli P43/6/78 N-acetylglucosamine 6 phosphate deacetylase YP_007234095.1 553762 D 1042417 CDS YP_007234096.1 431807198 14293367 555741..556175 1 NC_019908.1 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; phenylacetic acid degradation-like protein 556175 14293367 BPP43_02625 Brachyspira pilosicoli P43/6/78 phenylacetic acid degradation-like protein YP_007234096.1 555741 D 1042417 CDS YP_007234097.1 431807199 14293368 556175..556963 1 NC_019908.1 COG0345 Pyrroline-5-carboxylate reductase; pyrroline 5 carboxylate reductase 556963 14293368 BPP43_02630 Brachyspira pilosicoli P43/6/78 pyrroline 5 carboxylate reductase YP_007234097.1 556175 D 1042417 CDS YP_007234098.1 431807200 14293369 557085..557447 1 NC_019908.1 COG0784 FOG: CheY-like receiver; two-component response regulator\ 557447 14293369 BPP43_02635 Brachyspira pilosicoli P43/6/78 two-component response regulator\ YP_007234098.1 557085 D 1042417 CDS YP_007234099.1 431807201 14293370 557447..558445 1 NC_019908.1 COG1085 Galactose-1-phosphate uridylyltransferase; galactose-1-phosphate uridylyltransferase 558445 14293370 BPP43_02640 Brachyspira pilosicoli P43/6/78 galactose-1-phosphate uridylyltransferase YP_007234099.1 557447 D 1042417 CDS YP_007234100.1 431807202 14293371 complement(558450..559304) 1 NC_019908.1 COG2264 Ribosomal protein L11 methylase; 50S ribosomal protein L11 methyltransferase 559304 14293371 BPP43_02645 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L11 methyltransferase YP_007234100.1 558450 R 1042417 CDS YP_007234101.1 431807203 14293372 complement(559310..561289) 1 NC_019908.1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); hypothetical protein 561289 14293372 BPP43_02650 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234101.1 559310 R 1042417 CDS YP_007234102.1 431807204 14293373 561778..563865 1 NC_019908.1 COG3968 Uncharacterized protein related to glutamine synthetase; glutamine synthetase 563865 14293373 BPP43_02655 Brachyspira pilosicoli P43/6/78 glutamine synthetase YP_007234102.1 561778 D 1042417 CDS YP_007234103.1 431807205 14293374 complement(563940..564182) 1 NC_019908.1 hypothetical protein 564182 14293374 BPP43_02660 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234103.1 563940 R 1042417 CDS YP_007234104.1 431807206 14293375 complement(564408..568712) 1 NC_019908.1 COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); CoA-enzyme activase 568712 14293375 BPP43_02665 Brachyspira pilosicoli P43/6/78 CoA-enzyme activase YP_007234104.1 564408 R 1042417 CDS YP_007234105.1 431807207 14293376 complement(568764..569114) 1 NC_019908.1 COG0853 Aspartate 1-decarboxylase; aspartate alpha-decarboxylase 569114 14293376 BPP43_02670 Brachyspira pilosicoli P43/6/78 aspartate alpha-decarboxylase YP_007234105.1 568764 R 1042417 CDS YP_007234106.1 431807208 14293377 569375..570454 1 NC_019908.1 COG2391 Predicted transporter component; hypothetical protein 570454 14293377 BPP43_02675 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234106.1 569375 D 1042417 CDS YP_007234107.1 431807209 14293378 570687..570920 1 NC_019908.1 SirA family protein 570920 14293378 BPP43_02680 Brachyspira pilosicoli P43/6/78 SirA family protein YP_007234107.1 570687 D 1042417 CDS YP_007234108.1 431807210 14293379 570999..572297 1 NC_019908.1 COG0014 Gamma-glutamyl phosphate reductase; gamma glutamyl phosphate reductase 572297 14293379 BPP43_02685 Brachyspira pilosicoli P43/6/78 gamma glutamyl phosphate reductase YP_007234108.1 570999 D 1042417 CDS YP_007234109.1 431807211 14293380 complement(572331..572645) 1 NC_019908.1 COG3339 Uncharacterized conserved protein; hypothetical protein 572645 14293380 BPP43_02690 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234109.1 572331 R 1042417 CDS YP_007234110.1 431807212 14293381 complement(572696..573259) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 573259 14293381 BPP43_02695 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234110.1 572696 R 1042417 CDS YP_007234111.1 431807213 14293382 573386..573700 1 NC_019908.1 COG1925 Phosphotransferase system, HPr-related proteins; phosphocarrier protein HPr 573700 14293382 BPP43_02700 Brachyspira pilosicoli P43/6/78 phosphocarrier protein HPr YP_007234111.1 573386 D 1042417 CDS YP_007234112.1 431807214 14293383 573746..575131 1 NC_019908.1 COG2610 H+/gluconate symporter and related permeases; gluconate transporter 575131 14293383 BPP43_02705 Brachyspira pilosicoli P43/6/78 gluconate transporter YP_007234112.1 573746 D 1042417 CDS YP_007234113.1 431807215 14293384 575148..575582 1 NC_019908.1 COG0756 dUTPase; deoxyuridine-5-triphosphate nucleotidohydrolase 575582 14293384 BPP43_02710 Brachyspira pilosicoli P43/6/78 deoxyuridine-5-triphosphate nucleotidohydrolase YP_007234113.1 575148 D 1042417 CDS YP_007234114.1 431807216 14293385 complement(577000..577338) 1 NC_019908.1 COG3187 Heat shock protein; hypothetical protein 577338 14293385 BPP43_02725 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234114.1 577000 R 1042417 CDS YP_007234115.1 431807217 14293386 complement(577398..577652) 1 NC_019908.1 hypothetical protein 577652 14293386 BPP43_02730 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234115.1 577398 R 1042417 CDS YP_007234116.1 431807218 14293387 complement(577781..577888) 1 NC_019908.1 hypothetical protein 577888 14293387 BPP43_02735 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234116.1 577781 R 1042417 CDS YP_007234117.1 431807219 14293388 578021..578701 1 NC_019908.1 hypothetical protein 578701 14293388 BPP43_02740 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234117.1 578021 D 1042417 CDS YP_007234118.1 431807220 14293389 578733..579392 1 NC_019908.1 COG0819 Putative transcription activator; transcription activator 579392 14293389 BPP43_02745 Brachyspira pilosicoli P43/6/78 transcription activator YP_007234118.1 578733 D 1042417 CDS YP_007234119.1 431807221 14293390 complement(579393..580610) 1 NC_019908.1 COG0827 Adenine-specific DNA methylase; modification methylase BsuBI 580610 14293390 BPP43_02750 Brachyspira pilosicoli P43/6/78 modification methylase BsuBI YP_007234119.1 579393 R 1042417 CDS YP_007234120.1 431807222 14293391 complement(580621..581325) 1 NC_019908.1 hypothetical protein 581325 14293391 BPP43_02755 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234120.1 580621 R 1042417 CDS YP_007234121.1 431807223 14293392 complement(581363..581968) 1 NC_019908.1 COG2128 Uncharacterized conserved protein; hypothetical protein 581968 14293392 BPP43_02760 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234121.1 581363 R 1042417 CDS YP_007234122.1 431807224 14293393 complement(581982..585332) 1 NC_019908.1 COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); UvrD/REP helicase 585332 14293393 BPP43_02765 Brachyspira pilosicoli P43/6/78 UvrD/REP helicase YP_007234122.1 581982 R 1042417 CDS YP_007234123.1 431807225 14293394 585435..585713 1 NC_019908.1 COG1254 Acylphosphatases; acylphosphatase 585713 14293394 BPP43_02770 Brachyspira pilosicoli P43/6/78 acylphosphatase YP_007234123.1 585435 D 1042417 CDS YP_007234124.1 431807226 14293395 585735..587825 1 NC_019908.1 COG0739 Membrane proteins related to metalloendopeptidases; peptidoglycan-binding LysM 587825 14293395 BPP43_02775 Brachyspira pilosicoli P43/6/78 peptidoglycan-binding LysM YP_007234124.1 585735 D 1042417 CDS YP_007234125.1 431807227 14293396 complement(587922..588665) 1 NC_019908.1 COG1285 Uncharacterized membrane protein; MgtC family protein 588665 14293396 BPP43_02780 Brachyspira pilosicoli P43/6/78 MgtC family protein YP_007234125.1 587922 R 1042417 CDS YP_007234126.1 431807228 14293397 complement(588693..589739) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 589739 14293397 BPP43_02785 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234126.1 588693 R 1042417 CDS YP_007234127.1 431807229 14293398 589840..590508 1 NC_019908.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; ribosomal large subunit pseudouridine synthase D 590508 14293398 BPP43_02790 Brachyspira pilosicoli P43/6/78 ribosomal large subunit pseudouridine synthase D YP_007234127.1 589840 D 1042417 CDS YP_007234128.1 431807230 14293399 complement(590509..591768) 1 NC_019908.1 COG0460 Homoserine dehydrogenase; homoserine dehydrogenase 591768 14293399 BPP43_02795 Brachyspira pilosicoli P43/6/78 homoserine dehydrogenase YP_007234128.1 590509 R 1042417 CDS YP_007234129.1 431807231 14293400 complement(591911..593761) 1 NC_019908.1 COG1154 Deoxyxylulose-5-phosphate synthase; 1-deoxy-D-xylulose-5-phosphate synthase 593761 14293400 BPP43_02800 Brachyspira pilosicoli P43/6/78 1-deoxy-D-xylulose-5-phosphate synthase YP_007234129.1 591911 R 1042417 CDS YP_007234130.1 431807232 14293401 complement(593823..594728) 1 NC_019908.1 hypothetical protein 594728 14293401 BPP43_02805 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234130.1 593823 R 1042417 CDS YP_007234131.1 431807233 14293402 595199..596392 1 NC_019908.1 COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; metal-dependent amidase/aminoacylase/carboxypeptidase AbgB 596392 14293402 BPP43_02810 Brachyspira pilosicoli P43/6/78 metal-dependent amidase/aminoacylase/carboxypeptidase AbgB YP_007234131.1 595199 D 1042417 CDS YP_007234132.1 431807234 14293403 596415..597296 1 NC_019908.1 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase 597296 14293403 BPP43_02815 Brachyspira pilosicoli P43/6/78 dihydrodipicolinate synthase YP_007234132.1 596415 D 1042417 CDS YP_007234133.1 431807235 14293404 597293..597997 1 NC_019908.1 COG0289 Dihydrodipicolinate reductase; dihydrodipicolinate reductase 597997 14293404 BPP43_02820 Brachyspira pilosicoli P43/6/78 dihydrodipicolinate reductase YP_007234133.1 597293 D 1042417 CDS YP_007234134.1 431807236 14293405 598388..599527 1 NC_019908.1 COG1834 N-Dimethylarginine dimethylaminohydrolase; glycine amidinotransferase 599527 14293405 BPP43_02825 Brachyspira pilosicoli P43/6/78 glycine amidinotransferase YP_007234134.1 598388 D 1042417 CDS YP_007234135.1 431807237 14293406 complement(599723..601078) 1 NC_019908.1 COG0534 Na+-driven multidrug efflux pump; MATE efflux family protein 601078 14293406 BPP43_02830 Brachyspira pilosicoli P43/6/78 MATE efflux family protein YP_007234135.1 599723 R 1042417 CDS YP_007234136.1 431807238 14293407 601254..601820 1 NC_019908.1 COG1247 Sortase and related acyltransferases; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 601820 14293407 BPP43_02835 Brachyspira pilosicoli P43/6/78 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_007234136.1 601254 D 1042417 CDS YP_007234137.1 431807239 14293408 601999..603252 1 NC_019908.1 COG1344 Flagellin and related hook-associated proteins; flagellar hook-associated protein FlgL 603252 14293408 BPP43_02840 Brachyspira pilosicoli P43/6/78 flagellar hook-associated protein FlgL YP_007234137.1 601999 D 1042417 CDS YP_007234138.1 431807240 14293409 603296..603766 1 NC_019908.1 COG1699 Uncharacterized protein conserved in bacteria; flagellar assembly protein FliW 603766 14293409 BPP43_02845 Brachyspira pilosicoli P43/6/78 flagellar assembly protein FliW YP_007234138.1 603296 D 1042417 CDS YP_007234139.1 431807241 14293410 603770..604015 1 NC_019908.1 COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing); carbon storage regulator CsrA 604015 14293410 BPP43_02850 Brachyspira pilosicoli P43/6/78 carbon storage regulator CsrA YP_007234139.1 603770 D 1042417 CDS YP_007234140.1 431807242 14293411 complement(604019..604822) 1 NC_019908.1 COG0796 Glutamate racemase; glutamate racemase 604822 14293411 BPP43_02855 Brachyspira pilosicoli P43/6/78 glutamate racemase YP_007234140.1 604019 R 1042417 CDS YP_007234141.1 431807243 14293412 604975..605214 1 NC_019908.1 hypothetical protein 605214 14293412 BPP43_02860 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234141.1 604975 D 1042417 CDS YP_007234142.1 431807244 14293413 605240..607045 1 NC_019908.1 COG5016 Pyruvate/oxaloacetate carboxyltransferase; biotin/lipoyl attachment domain-containing protein 607045 14293413 BPP43_02865 Brachyspira pilosicoli P43/6/78 biotin/lipoyl attachment domain-containing protein YP_007234142.1 605240 D 1042417 CDS YP_007234143.1 431807245 14293414 607074..608453 1 NC_019908.1 COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; sodium transporting methylmalonyl-CoA/oxaloacetate decarboxylase subunit beta 608453 14293414 BPP43_02870 Brachyspira pilosicoli P43/6/78 sodium transporting methylmalonyl-CoA/oxaloacetate decarboxylase subunit beta YP_007234143.1 607074 D 1042417 CDS YP_007234144.1 431807246 14293415 complement(608568..609602) 1 NC_019908.1 COG1082 Sugar phosphate isomerases/epimerases; hypothetical protein 609602 14293415 BPP43_02875 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234144.1 608568 R 1042417 CDS YP_007234145.1 431807247 14293416 complement(609599..610888) 1 NC_019908.1 COG0477 Permeases of the major facilitator superfamily; MFS superfamily transporter 610888 14293416 BPP43_02880 Brachyspira pilosicoli P43/6/78 MFS superfamily transporter YP_007234145.1 609599 R 1042417 CDS YP_007234146.1 431807248 14293417 611105..612139 1 NC_019908.1 COG3872 Predicted metal-dependent enzyme; metal-dependent enzyme 612139 14293417 BPP43_02885 Brachyspira pilosicoli P43/6/78 metal-dependent enzyme YP_007234146.1 611105 D 1042417 CDS YP_007234147.1 431807249 14293418 612130..613251 1 NC_019908.1 hypothetical protein 613251 14293418 BPP43_02890 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234147.1 612130 D 1042417 CDS YP_007234148.1 431807250 14293419 complement(613323..614795) 1 NC_019908.1 COG1145 Ferredoxin; Fe-hydrogenase large subunit family protein 614795 14293419 BPP43_02895 Brachyspira pilosicoli P43/6/78 Fe-hydrogenase large subunit family protein YP_007234148.1 613323 R 1042417 CDS YP_007234149.1 431807251 14293420 615100..616209 1 NC_019908.1 COG0686 Alanine dehydrogenase; alanine dehydrogenase 616209 14293420 BPP43_02900 Brachyspira pilosicoli P43/6/78 alanine dehydrogenase YP_007234149.1 615100 D 1042417 CDS YP_007234150.1 431807252 14293421 complement(616289..617026) 1 NC_019908.1 hypothetical protein 617026 14293421 BPP43_02905 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234150.1 616289 R 1042417 CDS YP_007234151.1 431807253 14293422 617335..618009 1 NC_019908.1 hypothetical protein 618009 14293422 BPP43_02910 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234151.1 617335 D 1042417 CDS YP_007234152.1 431807254 14293423 619469..621103 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 621103 14293423 BPP43_02925 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234152.1 619469 D 1042417 CDS YP_007234153.1 431807255 14293424 complement(622035..624242) 1 NC_019908.1 COG1345 Flagellar capping protein; flagellar hook associated protein FliD 624242 14293424 BPP43_02940 Brachyspira pilosicoli P43/6/78 flagellar hook associated protein FliD YP_007234153.1 622035 R 1042417 CDS YP_007234154.1 431807256 14293425 complement(624379..624804) 1 NC_019908.1 COG1396 Predicted transcriptional regulators; transcriptional regulator 624804 14293425 BPP43_02945 Brachyspira pilosicoli P43/6/78 transcriptional regulator YP_007234154.1 624379 R 1042417 CDS YP_007234155.1 431807257 14293426 complement(624808..625500) 1 NC_019908.1 COG2003 DNA repair proteins; DNA repair protein RadC 625500 14293426 BPP43_02950 Brachyspira pilosicoli P43/6/78 DNA repair protein RadC YP_007234155.1 624808 R 1042417 CDS YP_007234156.1 431807258 14293427 625712..626737 1 NC_019908.1 hypothetical protein 626737 14293427 BPP43_02955 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234156.1 625712 D 1042417 CDS YP_007234157.1 431807259 14293428 626877..627323 1 NC_019908.1 hypothetical protein 627323 14293428 BPP43_02960 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234157.1 626877 D 1042417 CDS YP_007234158.1 431807260 14293429 627442..627951 1 NC_019908.1 hypothetical protein 627951 14293429 BPP43_02965 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234158.1 627442 D 1042417 CDS YP_007234159.1 431807261 14293430 628063..628290 1 NC_019908.1 hypothetical protein 628290 14293430 BPP43_02970 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234159.1 628063 D 1042417 CDS YP_007234160.1 431807262 14293431 628323..629147 1 NC_019908.1 COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; pyridoxamine kinase PdxY 629147 14293431 BPP43_02975 Brachyspira pilosicoli P43/6/78 pyridoxamine kinase PdxY YP_007234160.1 628323 D 1042417 CDS YP_007234161.1 431807263 14293432 complement(629157..631907) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 631907 14293432 BPP43_02980 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234161.1 629157 R 1042417 CDS YP_007234162.1 431807264 14293433 631983..633038 1 NC_019908.1 COG0438 Glycosyltransferase; hypothetical protein 633038 14293433 BPP43_02985 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234162.1 631983 D 1042417 CDS YP_007234163.1 431807265 14293434 complement(633033..634163) 1 NC_019908.1 COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; chaperone protein 634163 14293434 BPP43_02990 Brachyspira pilosicoli P43/6/78 chaperone protein YP_007234163.1 633033 R 1042417 CDS YP_007234164.1 431807266 14293435 complement(634241..634528) 1 NC_019908.1 COG2214 DnaJ-class molecular chaperone; chaperone protein DnaJ 634528 14293435 BPP43_02995 Brachyspira pilosicoli P43/6/78 chaperone protein DnaJ YP_007234164.1 634241 R 1042417 CDS YP_007234165.1 431807267 14293436 complement(634587..635279) 1 NC_019908.1 COG3619 Predicted membrane protein; hypothetical protein 635279 14293436 BPP43_03000 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234165.1 634587 R 1042417 CDS YP_007234166.1 431807268 14293437 complement(635369..635464) 1 NC_019908.1 modification methylase 635464 14293437 BPP43_03005 Brachyspira pilosicoli P43/6/78 modification methylase YP_007234166.1 635369 R 1042417 CDS YP_007234167.1 431807269 14293438 complement(635457..635792) 1 NC_019908.1 COG3187 Heat shock protein; modification methylase 635792 14293438 BPP43_03010 Brachyspira pilosicoli P43/6/78 modification methylase YP_007234167.1 635457 R 1042417 CDS YP_007234168.1 431807270 14293439 complement(635789..636199) 1 NC_019908.1 COG3187 Heat shock protein; heat shock protein HslJ 636199 14293439 BPP43_03015 Brachyspira pilosicoli P43/6/78 heat shock protein HslJ YP_007234168.1 635789 R 1042417 CDS YP_007234169.1 431807271 14293440 complement(636333..637931) 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; hypothetical protein 637931 14293440 BPP43_03020 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234169.1 636333 R 1042417 CDS YP_007234170.1 431807272 14293441 complement(640026..640472) 1 NC_019908.1 COG0307 Riboflavin synthase alpha chain; hypothetical protein 640472 14293441 BPP43_03035 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234170.1 640026 R 1042417 CDS YP_007234171.1 431807273 14293442 complement(640590..641294) 1 NC_019908.1 COG1847 Predicted RNA-binding protein; jag protein 641294 14293442 BPP43_03040 Brachyspira pilosicoli P43/6/78 jag protein YP_007234171.1 640590 R 1042417 CDS YP_007234172.1 431807274 14293443 complement(641321..643129) 1 NC_019908.1 COG0706 Preprotein translocase subunit YidC; 60 kDa inner membrane insertion protein 643129 14293443 BPP43_03045 Brachyspira pilosicoli P43/6/78 60 kDa inner membrane insertion protein YP_007234172.1 641321 R 1042417 CDS YP_007234173.1 431807275 14293444 complement(643232..643432) 1 NC_019908.1 COG0759 Uncharacterized conserved protein; hypothetical protein 643432 14293444 BPP43_03050 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234173.1 643232 R 1042417 CDS YP_007234174.1 431807276 14293445 complement(643614..643865) 1 NC_019908.1 ribonuclease P protein component 643865 14293445 BPP43_03055 Brachyspira pilosicoli P43/6/78 ribonuclease P protein component YP_007234174.1 643614 R 1042417 CDS YP_007234175.1 431807277 14293446 complement(643858..644001) 1 NC_019908.1 50S ribosomal protein L34 644001 14293446 BPP43_03060 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L34 YP_007234175.1 643858 R 1042417 CDS YP_007234176.1 431807278 14293447 complement(644153..644455) 1 NC_019908.1 hypothetical protein 644455 14293447 BPP43_03065 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234176.1 644153 R 1042417 CDS YP_007234177.1 431807279 14293448 644533..645108 1 NC_019908.1 hypothetical protein 645108 14293448 BPP43_03070 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234177.1 644533 D 1042417 CDS YP_007234178.1 431807280 14293449 complement(647437..648834) 1 NC_019908.1 COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; hypothetical protein 648834 14293449 BPP43_03085 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234178.1 647437 R 1042417 CDS YP_007234179.1 431807281 14293450 complement(648960..649358) 1 NC_019908.1 lipoprotein 649358 14293450 BPP43_03090 Brachyspira pilosicoli P43/6/78 lipoprotein YP_007234179.1 648960 R 1042417 CDS YP_007234180.1 431807282 14293451 complement(649418..650203) 1 NC_019908.1 TPR domain-containing protein 650203 14293451 BPP43_03095 Brachyspira pilosicoli P43/6/78 TPR domain-containing protein YP_007234180.1 649418 R 1042417 CDS YP_007234181.1 431807283 14293452 complement(650330..651439) 1 NC_019908.1 glycosyltransferase 651439 14293452 BPP43_03100 Brachyspira pilosicoli P43/6/78 glycosyltransferase YP_007234181.1 650330 R 1042417 CDS YP_007234182.1 431807284 14293453 complement(651449..652882) 1 NC_019908.1 glycosyltransferase 652882 14293453 BPP43_03105 Brachyspira pilosicoli P43/6/78 glycosyltransferase YP_007234182.1 651449 R 1042417 CDS YP_007234183.1 431807285 14293454 complement(653051..653800) 1 NC_019908.1 hypothetical protein 653800 14293454 BPP43_03110 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234183.1 653051 R 1042417 CDS YP_007234184.1 431807286 14293455 complement(653836..654348) 1 NC_019908.1 COG0535 Predicted Fe-S oxidoreductases; radical SAM domain-containing protein 654348 14293455 BPP43_03115 Brachyspira pilosicoli P43/6/78 radical SAM domain-containing protein YP_007234184.1 653836 R 1042417 CDS YP_007234185.1 431807287 14293456 complement(654897..655982) 1 NC_019908.1 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase 655982 14293456 BPP43_03120 Brachyspira pilosicoli P43/6/78 SAM-dependent methyltransferase YP_007234185.1 654897 R 1042417 CDS YP_007234186.1 431807288 14293457 656151..656303 1 NC_019908.1 hypothetical protein 656303 14293457 BPP43_03125 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234186.1 656151 D 1042417 CDS YP_007234187.1 431807289 14293458 complement(656379..657911) 1 NC_019908.1 COG1190 Lysyl-tRNA synthetase (class II); lysyl-tRNA-synthetase LysU class II 657911 14293458 BPP43_03130 Brachyspira pilosicoli P43/6/78 lysyl-tRNA-synthetase LysU class II YP_007234187.1 656379 R 1042417 CDS YP_007234188.1 431807290 14293459 complement(658052..658552) 1 NC_019908.1 hypothetical protein 658552 14293459 BPP43_03135 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234188.1 658052 R 1042417 CDS YP_007234189.1 431807291 14293460 complement(658611..659243) 1 NC_019908.1 cytidylate kinase 659243 14293460 BPP43_03140 Brachyspira pilosicoli P43/6/78 cytidylate kinase YP_007234189.1 658611 R 1042417 CDS YP_007234190.1 431807292 14293461 659405..661357 1 NC_019908.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter 661357 14293461 BPP43_03145 Brachyspira pilosicoli P43/6/78 ABC transporter YP_007234190.1 659405 D 1042417 CDS YP_007234191.1 431807293 14293462 661365..661964 1 NC_019908.1 COG0127 Xanthosine triphosphate pyrophosphatase; non-canonical purine NTP pyrophosphatase 661964 14293462 BPP43_03150 Brachyspira pilosicoli P43/6/78 non-canonical purine NTP pyrophosphatase YP_007234191.1 661365 D 1042417 CDS YP_007234192.1 431807294 14293463 662118..663152 1 NC_019908.1 COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; NADH:flavin oxidoreductase 663152 14293463 BPP43_03155 Brachyspira pilosicoli P43/6/78 NADH:flavin oxidoreductase YP_007234192.1 662118 D 1042417 CDS YP_007234193.1 431807295 14293464 complement(663332..665164) 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; tsr1 protein 665164 14293464 BPP43_03160 Brachyspira pilosicoli P43/6/78 tsr1 protein YP_007234193.1 663332 R 1042417 CDS YP_007234194.1 431807296 14293465 665404..667251 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 667251 14293465 BPP43_03165 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234194.1 665404 D 1042417 CDS YP_007234195.1 431807297 14293466 667322..668284 1 NC_019908.1 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; oligopeptide dipeptide ABC transporter ATP-binding protein 668284 14293466 BPP43_03170 Brachyspira pilosicoli P43/6/78 oligopeptide dipeptide ABC transporter ATP-binding protein YP_007234195.1 667322 D 1042417 CDS YP_007234196.1 431807298 14293467 668309..669310 1 NC_019908.1 COG4608 ABC-type oligopeptide transport system, ATPase component; oligopeptide dipeptide ABC transporter ATP-binding protein C terminal 669310 14293467 BPP43_03175 Brachyspira pilosicoli P43/6/78 oligopeptide dipeptide ABC transporter ATP-binding protein C terminal YP_007234196.1 668309 D 1042417 CDS YP_007234197.1 431807299 14293468 complement(669315..670049) 1 NC_019908.1 hypothetical protein 670049 14293468 BPP43_03180 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234197.1 669315 R 1042417 CDS YP_007234198.1 431807300 14293469 complement(670052..670894) 1 NC_019908.1 hypothetical protein 670894 14293469 BPP43_03185 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234198.1 670052 R 1042417 CDS YP_007234199.1 431807301 14293470 complement(671070..672326) 1 NC_019908.1 COG0133 Tryptophan synthase beta chain; tryptophan synthase subunit beta 672326 14293470 BPP43_03190 Brachyspira pilosicoli P43/6/78 tryptophan synthase subunit beta YP_007234199.1 671070 R 1042417 CDS YP_007234200.1 431807302 14293471 672479..673840 1 NC_019908.1 COG0534 Na+-driven multidrug efflux pump; Na+ driven multidrug efflux pump 673840 14293471 BPP43_03195 Brachyspira pilosicoli P43/6/78 Na+ driven multidrug efflux pump YP_007234200.1 672479 D 1042417 CDS YP_007234201.1 431807303 14293472 complement(674059..675039) 1 NC_019908.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; monosaccharide transporting ATPase QYMF 675039 14293472 BPP43_03200 Brachyspira pilosicoli P43/6/78 monosaccharide transporting ATPase QYMF YP_007234201.1 674059 R 1042417 CDS YP_007234202.1 431807304 14293473 complement(675074..676573) 1 NC_019908.1 COG1129 ABC-type sugar transport system, ATPase component; hypothetical protein 676573 14293473 BPP43_03205 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234202.1 675074 R 1042417 CDS YP_007234203.1 431807305 14293474 complement(676654..677640) 1 NC_019908.1 COG1879 ABC-type sugar transport system, periplasmic component; ABC transporter substrate-binding protein 677640 14293474 BPP43_03210 Brachyspira pilosicoli P43/6/78 ABC transporter substrate-binding protein YP_007234203.1 676654 R 1042417 CDS YP_007234204.1 431807306 14293475 complement(677690..678457) 1 NC_019908.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); hypothetical protein 678457 14293475 BPP43_03215 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234204.1 677690 R 1042417 CDS YP_007234205.1 431807307 14293476 complement(678478..679521) 1 NC_019908.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; sorbitol dehydrogenase 679521 14293476 BPP43_03220 Brachyspira pilosicoli P43/6/78 sorbitol dehydrogenase YP_007234205.1 678478 R 1042417 CDS YP_007234206.1 431807308 14293477 complement(679653..680624) 1 NC_019908.1 COG1940 Transcriptional regulator/sugar kinase; ROK family glucose kinase 680624 14293477 BPP43_03225 Brachyspira pilosicoli P43/6/78 ROK family glucose kinase YP_007234206.1 679653 R 1042417 CDS YP_007234207.1 431807309 14293478 680919..681020 1 NC_019908.1 hypothetical protein 681020 14293478 BPP43_03230 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234207.1 680919 D 1042417 CDS YP_007234208.1 431807310 14293479 681049..682482 1 NC_019908.1 COG1070 Sugar (pentulose and hexulose) kinases; xylulose kinase 682482 14293479 BPP43_03235 Brachyspira pilosicoli P43/6/78 xylulose kinase YP_007234208.1 681049 D 1042417 CDS YP_007234209.1 431807311 14293480 complement(682515..682847) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 682847 14293480 BPP43_03240 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234209.1 682515 R 1042417 CDS YP_007234210.1 431807312 14293483 complement(685645..686214) 1 NC_019908.1 COG0563 Adenylate kinase and related kinases; adenylate kinase 686214 14293483 BPP43_03265 Brachyspira pilosicoli P43/6/78 adenylate kinase YP_007234210.1 685645 R 1042417 CDS YP_007234211.1 431807313 14293484 complement(686292..687887) 1 NC_019908.1 hypothetical protein 687887 14293484 BPP43_03270 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234211.1 686292 R 1042417 CDS YP_007234212.1 431807314 14293485 690626..691048 1 NC_019908.1 hypothetical protein 691048 14293485 BPP43_03285 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234212.1 690626 D 1042417 CDS YP_007234213.1 431807315 14293486 complement(691050..692066) 1 NC_019908.1 COG0451 Nucleoside-diphosphate-sugar epimerases; ADP-L-glycero-D-mannoheptose 6-epimerase 692066 14293486 BPP43_03290 Brachyspira pilosicoli P43/6/78 ADP-L-glycero-D-mannoheptose 6-epimerase YP_007234213.1 691050 R 1042417 CDS YP_007234214.1 431807316 14293487 complement(692026..693108) 1 NC_019908.1 COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; N-acetylglucosaminyl transferase 693108 14293487 BPP43_03295 Brachyspira pilosicoli P43/6/78 N-acetylglucosaminyl transferase YP_007234214.1 692026 R 1042417 CDS YP_007234215.1 431807317 14293488 complement(693105..694199) 1 NC_019908.1 COG0772 Bacterial cell division membrane protein; cell division protein FtsW 694199 14293488 BPP43_03300 Brachyspira pilosicoli P43/6/78 cell division protein FtsW YP_007234215.1 693105 R 1042417 CDS YP_007234216.1 431807318 14293489 complement(694213..695082) 1 NC_019908.1 hypothetical protein 695082 14293489 BPP43_03305 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234216.1 694213 R 1042417 CDS YP_007234217.1 431807319 14293490 complement(695242..696528) 1 NC_019908.1 COG0448 ADP-glucose pyrophosphorylase; glucose-1-phosphate adenylyltransferase 696528 glgC 14293490 glgC Brachyspira pilosicoli P43/6/78 glucose-1-phosphate adenylyltransferase YP_007234217.1 695242 R 1042417 CDS YP_007234218.1 431807320 14293491 complement(696614..697000) 1 NC_019908.1 hypothetical protein 697000 14293491 BPP43_03315 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234218.1 696614 R 1042417 CDS YP_007234219.1 431807321 14293492 complement(697055..697450) 1 NC_019908.1 hypothetical protein 697450 14293492 BPP43_03320 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234219.1 697055 R 1042417 CDS YP_007234220.1 431807322 14293493 697624..698007 1 NC_019908.1 COG0607 Rhodanese-related sulfurtransferase; rhodanese domain-containing protein 698007 14293493 BPP43_03325 Brachyspira pilosicoli P43/6/78 rhodanese domain-containing protein YP_007234220.1 697624 D 1042417 CDS YP_007234221.1 431807323 14293494 700901..701506 1 NC_019908.1 COG0560 Phosphoserine phosphatase; phosphoserine phosphatase SerB 701506 14293494 BPP43_03340 Brachyspira pilosicoli P43/6/78 phosphoserine phosphatase SerB YP_007234221.1 700901 D 1042417 CDS YP_007234222.1 431807324 14293495 701522..701650 1 NC_019908.1 hypothetical protein 701650 14293495 BPP43_03345 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234222.1 701522 D 1042417 CDS YP_007234223.1 431807325 14293496 701740..702573 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 702573 14293496 BPP43_03350 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234223.1 701740 D 1042417 CDS YP_007234224.1 431807326 14293497 702570..703394 1 NC_019908.1 COG2199 FOG: GGDEF domain; GGDEF domain-containing protein 703394 14293497 BPP43_03355 Brachyspira pilosicoli P43/6/78 GGDEF domain-containing protein YP_007234224.1 702570 D 1042417 CDS YP_007234225.1 431807327 14293498 complement(703360..704352) 1 NC_019908.1 hypothetical protein 704352 14293498 BPP43_03360 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234225.1 703360 R 1042417 CDS YP_007234226.1 431807328 14293499 complement(704571..705278) 1 NC_019908.1 COG2364 Predicted membrane protein; hypothetical protein 705278 14293499 BPP43_03365 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234226.1 704571 R 1042417 CDS YP_007234227.1 431807329 14293500 complement(711532..711867) 1 NC_019908.1 COG2827 Predicted endonuclease containing a URI domain; excinuclease ABC subunit C 711867 14293500 BPP43_03380 Brachyspira pilosicoli P43/6/78 excinuclease ABC subunit C YP_007234227.1 711532 R 1042417 CDS YP_007234228.1 431807330 14293501 complement(711857..712537) 1 NC_019908.1 COG1861 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog; spore coat polysaccharide biosynthesis protein F 712537 14293501 BPP43_03385 Brachyspira pilosicoli P43/6/78 spore coat polysaccharide biosynthesis protein F YP_007234228.1 711857 R 1042417 CDS YP_007234229.1 431807331 14293502 complement(712564..713424) 1 NC_019908.1 COG0130 Pseudouridine synthase; pseudouridylate synthase 713424 14293502 BPP43_03390 Brachyspira pilosicoli P43/6/78 pseudouridylate synthase YP_007234229.1 712564 R 1042417 CDS YP_007234230.1 431807332 14293503 complement(713453..714193) 1 NC_019908.1 hypothetical protein 714193 14293503 BPP43_03395 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234230.1 713453 R 1042417 CDS YP_007234231.1 431807333 14293504 714256..714546 1 NC_019908.1 hypothetical protein 714546 14293504 BPP43_03400 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234231.1 714256 D 1042417 CDS YP_007234232.1 431807334 14293505 714710..714880 1 NC_019908.1 hypothetical protein 714880 14293505 BPP43_03405 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234232.1 714710 D 1042417 CDS YP_007234233.1 431807335 14293506 714938..715567 1 NC_019908.1 COG0811 Biopolymer transport proteins; biopolymer transport protein ExbB 715567 14293506 BPP43_03410 Brachyspira pilosicoli P43/6/78 biopolymer transport protein ExbB YP_007234233.1 714938 D 1042417 CDS YP_007234234.1 431807336 14293507 complement(715839..716843) 1 NC_019908.1 COG0180 Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase 716843 14293507 BPP43_03415 Brachyspira pilosicoli P43/6/78 tryptophanyl-tRNA synthetase YP_007234234.1 715839 R 1042417 CDS YP_007234235.1 431807337 14293508 complement(716877..717827) 1 NC_019908.1 COG1774 Uncharacterized homolog of PSP1; Psp1 protein 717827 14293508 BPP43_03420 Brachyspira pilosicoli P43/6/78 Psp1 protein YP_007234235.1 716877 R 1042417 CDS YP_007234236.1 431807338 14293509 complement(717908..719785) 1 NC_019908.1 COG0388 Predicted amidohydrolase; NAD+ synthetase 719785 14293509 BPP43_03425 Brachyspira pilosicoli P43/6/78 NAD+ synthetase YP_007234236.1 717908 R 1042417 CDS YP_007234237.1 431807339 14293510 719937..720524 1 NC_019908.1 COG3467 Predicted flavin-nucleotide-binding protein; antibiotic resistance protein 720524 14293510 BPP43_03430 Brachyspira pilosicoli P43/6/78 antibiotic resistance protein YP_007234237.1 719937 D 1042417 CDS YP_007234238.1 431807340 14293511 720617..721168 1 NC_019908.1 COG0194 Guanylate kinase; guanylate kinase 721168 14293511 BPP43_03435 Brachyspira pilosicoli P43/6/78 guanylate kinase YP_007234238.1 720617 D 1042417 CDS YP_007234239.1 431807341 14293512 721186..721587 1 NC_019908.1 COG1758 DNA-directed RNA polymerase, subunit K/omega; hypothetical protein 721587 14293512 BPP43_03440 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234239.1 721186 D 1042417 CDS YP_007234240.1 431807342 14293513 721597..722535 1 NC_019908.1 COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; tRNA-delta(2)-isopentenylpyrophosphate transferase 722535 14293513 BPP43_03445 Brachyspira pilosicoli P43/6/78 tRNA-delta(2)-isopentenylpyrophosphate transferase YP_007234240.1 721597 D 1042417 CDS YP_007234241.1 431807343 14293514 722532..723146 1 NC_019908.1 hypothetical protein 723146 14293514 BPP43_03450 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234241.1 722532 D 1042417 CDS YP_007234242.1 431807344 14293515 complement(723150..723965) 1 NC_019908.1 COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; 2-dehydro-3-deoxyphosphooctonate aldolase 723965 14293515 BPP43_03455 Brachyspira pilosicoli P43/6/78 2-dehydro-3-deoxyphosphooctonate aldolase YP_007234242.1 723150 R 1042417 CDS YP_007234243.1 431807345 14293516 724285..725631 1 NC_019908.1 COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramoylalanyl-glutamyl-2, 6-diaminopimelate-alanyl-alanine ligase 725631 14293516 BPP43_03460 Brachyspira pilosicoli P43/6/78 UDP-N-acetylmuramoylalanyl-glutamyl-2, 6-diaminopimelate-alanyl-alanine ligase YP_007234243.1 724285 D 1042417 CDS YP_007234244.1 431807346 14293517 complement(725639..726445) 1 NC_019908.1 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component; ABC transporter permease-like protein 726445 14293517 BPP43_03465 Brachyspira pilosicoli P43/6/78 ABC transporter permease-like protein YP_007234244.1 725639 R 1042417 CDS YP_007234245.1 431807347 14293518 complement(726463..727860) 1 NC_019908.1 COG0305 Replicative DNA helicase; replicative DNA helicase 727860 14293518 BPP43_03470 Brachyspira pilosicoli P43/6/78 replicative DNA helicase YP_007234245.1 726463 R 1042417 CDS YP_007234246.1 431807348 14293519 complement(727860..728381) 1 NC_019908.1 COG0359 Ribosomal protein L9; 50S ribosomal protein L9 728381 14293519 BPP43_03475 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L9 YP_007234246.1 727860 R 1042417 CDS YP_007234247.1 431807349 14293520 complement(728488..729345) 1 NC_019908.1 COG0739 Membrane proteins related to metalloendopeptidases; peptidase 729345 14293520 BPP43_03480 Brachyspira pilosicoli P43/6/78 peptidase YP_007234247.1 728488 R 1042417 CDS YP_007234248.1 431807350 14293521 complement(729342..730511) 1 NC_019908.1 hypothetical protein 730511 14293521 BPP43_03485 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234248.1 729342 R 1042417 CDS YP_007234249.1 431807351 14293522 complement(730518..731696) 1 NC_019908.1 COG0739 Membrane proteins related to metalloendopeptidases; M23/M37 family peptidase 731696 14293522 BPP43_03490 Brachyspira pilosicoli P43/6/78 M23/M37 family peptidase YP_007234249.1 730518 R 1042417 CDS YP_007234250.1 431807352 14293523 732610..733374 1 NC_019908.1 COG1192 ATPases involved in chromosome partitioning; cobyrinic acid ac-diamide synthase 733374 14293523 BPP43_03505 Brachyspira pilosicoli P43/6/78 cobyrinic acid ac-diamide synthase YP_007234250.1 732610 D 1042417 CDS YP_007234251.1 431807353 14293524 733394..734341 1 NC_019908.1 COG1475 Predicted transcriptional regulators; stage 0 sporulation protein J 734341 14293524 BPP43_03510 Brachyspira pilosicoli P43/6/78 stage 0 sporulation protein J YP_007234251.1 733394 D 1042417 CDS YP_007234252.1 431807354 14293525 734353..735546 1 NC_019908.1 hypothetical protein 735546 14293525 BPP43_03515 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234252.1 734353 D 1042417 CDS YP_007234253.1 431807355 14293526 735609..737405 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein B 737405 14293526 BPP43_03520 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis protein B YP_007234253.1 735609 D 1042417 CDS YP_007234254.1 431807356 14293527 complement(737402..738439) 1 NC_019908.1 COG0668 Small-conductance mechanosensitive channel; mechanosensitive ion channel protein 738439 14293527 BPP43_03525 Brachyspira pilosicoli P43/6/78 mechanosensitive ion channel protein YP_007234254.1 737402 R 1042417 CDS YP_007234255.1 431807357 14293528 complement(738676..740616) 1 NC_019908.1 COG2217 Cation transport ATPase; cadmium translocating P-type ATPase 740616 14293528 BPP43_03530 Brachyspira pilosicoli P43/6/78 cadmium translocating P-type ATPase YP_007234255.1 738676 R 1042417 CDS YP_007234256.1 431807358 14293529 complement(740603..740977) 1 NC_019908.1 COG0640 Predicted transcriptional regulators; arsR family transcriptional regulator 740977 14293529 BPP43_03535 Brachyspira pilosicoli P43/6/78 arsR family transcriptional regulator YP_007234256.1 740603 R 1042417 CDS YP_007234257.1 431807359 14293530 complement(741163..742545) 1 NC_019908.1 COG0733 Na+-dependent transporters of the SNF family; sodium/chloride-dependent transporter 742545 14293530 BPP43_03540 Brachyspira pilosicoli P43/6/78 sodium/chloride-dependent transporter YP_007234257.1 741163 R 1042417 CDS YP_007234258.1 431807360 14293531 742749..743195 1 NC_019908.1 COG1728 Uncharacterized protein conserved in bacteria; hypothetical protein 743195 14293531 BPP43_03545 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234258.1 742749 D 1042417 CDS YP_007234259.1 431807361 14293532 743192..743890 1 NC_019908.1 COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; molecular chaperone 743890 14293532 BPP43_03550 Brachyspira pilosicoli P43/6/78 molecular chaperone YP_007234259.1 743192 D 1042417 CDS YP_007234260.1 431807362 14293533 743983..746142 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein B 746142 14293533 BPP43_03555 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis protein B YP_007234260.1 743983 D 1042417 CDS YP_007234261.1 431807363 14293534 complement(746217..747242) 1 NC_019908.1 COG2603 Predicted ATPase; rhodanese like domain-containing protein 747242 14293534 BPP43_03560 Brachyspira pilosicoli P43/6/78 rhodanese like domain-containing protein YP_007234261.1 746217 R 1042417 CDS YP_007234262.1 431807364 14293535 complement(747264..748046) 1 NC_019908.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 748046 14293535 BPP43_03565 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234262.1 747264 R 1042417 CDS YP_007234263.1 431807365 14293536 748273..748539 1 NC_019908.1 COG0234 Co-chaperonin GroES (HSP10); co chaperonin GroES 748539 14293536 BPP43_03570 Brachyspira pilosicoli P43/6/78 co chaperonin GroES YP_007234263.1 748273 D 1042417 CDS YP_007234264.1 431807366 14293537 748635..749783 1 NC_019908.1 hypothetical protein 749783 14293537 BPP43_03575 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234264.1 748635 D 1042417 CDS YP_007234265.1 431807367 14293538 749889..750887 1 NC_019908.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 750887 14293538 BPP43_03580 Brachyspira pilosicoli P43/6/78 ABC transporter-like protein YP_007234265.1 749889 D 1042417 CDS YP_007234266.1 431807368 14293539 750925..751632 1 NC_019908.1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component; ABC transporter 751632 14293539 BPP43_03585 Brachyspira pilosicoli P43/6/78 ABC transporter YP_007234266.1 750925 D 1042417 CDS YP_007234267.1 431807369 14293540 751623..752231 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 752231 14293540 BPP43_03590 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234267.1 751623 D 1042417 CDS YP_007234268.1 431807370 14293541 752353..752562 1 NC_019908.1 COG2314 Predicted membrane protein; TM2 transmembrane domain 2 protein 752562 14293541 BPP43_03595 Brachyspira pilosicoli P43/6/78 TM2 transmembrane domain 2 protein YP_007234268.1 752353 D 1042417 CDS YP_007234269.1 431807371 14293542 complement(752635..753450) 1 NC_019908.1 COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; outer membrane lipoprotein 753450 14293542 BPP43_03600 Brachyspira pilosicoli P43/6/78 outer membrane lipoprotein YP_007234269.1 752635 R 1042417 CDS YP_007234270.1 431807372 14293543 complement(753499..754308) 1 NC_019908.1 COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; outer membrane lipoprotein 754308 14293543 BPP43_03605 Brachyspira pilosicoli P43/6/78 outer membrane lipoprotein YP_007234270.1 753499 R 1042417 CDS YP_007234271.1 431807373 14293544 complement(754388..755338) 1 NC_019908.1 COG0039 Malate/lactate dehydrogenases; L-lactate dehydrogenase 755338 14293544 BPP43_03610 Brachyspira pilosicoli P43/6/78 L-lactate dehydrogenase YP_007234271.1 754388 R 1042417 CDS YP_007234272.1 431807374 14293545 complement(755374..756054) 1 NC_019908.1 COG2011 ABC-type metal ion transport system, permease component; binding-protein-dependent transport system inner membrane protein 756054 14293545 BPP43_03615 Brachyspira pilosicoli P43/6/78 binding-protein-dependent transport system inner membrane protein YP_007234272.1 755374 R 1042417 CDS YP_007234273.1 431807375 14293546 complement(756035..757087) 1 NC_019908.1 COG1135 ABC-type metal ion transport system, ATPase component; ABC transporter-like protein 757087 14293546 BPP43_03620 Brachyspira pilosicoli P43/6/78 ABC transporter-like protein YP_007234273.1 756035 R 1042417 CDS YP_007234274.1 431807376 14293547 complement(774143..774898) 1 NC_019908.1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; ferrichrome transport ATP-binding protein FhuC 774898 14293547 BPP43_03635 Brachyspira pilosicoli P43/6/78 ferrichrome transport ATP-binding protein FhuC YP_007234274.1 774143 R 1042417 CDS YP_007234275.1 431807377 14293548 complement(774908..775897) 1 NC_019908.1 COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-compound ABC transporter permease 775897 14293548 BPP43_03640 Brachyspira pilosicoli P43/6/78 iron-compound ABC transporter permease YP_007234275.1 774908 R 1042417 CDS YP_007234276.1 431807378 14293549 complement(775903..776790) 1 NC_019908.1 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; iron-compound ABC transporter substrate-binding protein 776790 14293549 BPP43_03645 Brachyspira pilosicoli P43/6/78 iron-compound ABC transporter substrate-binding protein YP_007234276.1 775903 R 1042417 CDS YP_007234277.1 431807379 14293550 complement(776912..778582) 1 NC_019908.1 COG0539 Ribosomal protein S1; 30S ribosomal protein S1 778582 14293550 BPP43_03650 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S1 YP_007234277.1 776912 R 1042417 CDS YP_007234278.1 431807380 14293551 complement(778628..779017) 1 NC_019908.1 COG0283 Cytidylate kinase; cytidylate kinase Cmk 779017 14293551 BPP43_03655 Brachyspira pilosicoli P43/6/78 cytidylate kinase Cmk YP_007234278.1 778628 R 1042417 CDS YP_007234279.1 431807381 14293552 complement(779158..779307) 1 NC_019908.1 COG0283 Cytidylate kinase; hypothetical protein 779307 14293552 BPP43_03660 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234279.1 779158 R 1042417 CDS YP_007234280.1 431807382 14293553 complement(779418..779894) 1 NC_019908.1 COG0471 Di- and tricarboxylate transporters; hypothetical protein 779894 14293553 BPP43_03665 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234280.1 779418 R 1042417 CDS YP_007234281.1 431807383 14293554 780019..781008 1 NC_019908.1 hypothetical protein 781008 14293554 BPP43_03670 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234281.1 780019 D 1042417 CDS YP_007234282.1 431807384 14293555 781082..782008 1 NC_019908.1 COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase sigma factor RpoD 782008 14293555 BPP43_03675 Brachyspira pilosicoli P43/6/78 RNA polymerase sigma factor RpoD YP_007234282.1 781082 D 1042417 CDS YP_007234283.1 431807385 14293556 782111..782959 1 NC_019908.1 hypothetical protein 782959 14293556 BPP43_03680 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234283.1 782111 D 1042417 CDS YP_007234284.1 431807386 14293557 complement(783038..784126) 1 NC_019908.1 COG0371 Glycerol dehydrogenase and related enzymes; glycerol dehydrogenase 784126 14293557 BPP43_03685 Brachyspira pilosicoli P43/6/78 glycerol dehydrogenase YP_007234284.1 783038 R 1042417 CDS YP_007234285.1 431807387 14293558 complement(784147..785187) 1 NC_019908.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 785187 14293558 BPP43_03690 Brachyspira pilosicoli P43/6/78 diguanylate cyclase YP_007234285.1 784147 R 1042417 CDS YP_007234286.1 431807388 14293559 complement(785260..786225) 1 NC_019908.1 COG0863 DNA modification methylase; DNA methylase N-4/N-6 domain-containing protein 786225 14293559 BPP43_03695 Brachyspira pilosicoli P43/6/78 DNA methylase N-4/N-6 domain-containing protein YP_007234286.1 785260 R 1042417 CDS YP_007234287.1 431807389 14293560 complement(786235..787779) 1 NC_019908.1 COG0518 GMP synthase - Glutamine amidotransferase domain; bifunctional GMP synthase glutamine amidotransferase 787779 14293560 BPP43_03700 Brachyspira pilosicoli P43/6/78 bifunctional GMP synthase glutamine amidotransferase YP_007234287.1 786235 R 1042417 CDS YP_007234288.1 431807390 14293561 complement(788301..789170) 1 NC_019908.1 hypothetical protein 789170 14293561 BPP43_03705 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234288.1 788301 R 1042417 CDS YP_007234289.1 431807391 14293562 789478..790044 1 NC_019908.1 hypothetical protein 790044 14293562 BPP43_03710 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234289.1 789478 D 1042417 CDS YP_007234290.1 431807392 14293563 complement(790133..791329) 1 NC_019908.1 COG4857 Predicted kinase; methylthioribose kinase 791329 mtnK 14293563 mtnK Brachyspira pilosicoli P43/6/78 methylthioribose kinase YP_007234290.1 790133 R 1042417 CDS YP_007234291.1 431807393 14293564 791526..792008 1 NC_019908.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; response regulator 792008 14293564 BPP43_03720 Brachyspira pilosicoli P43/6/78 response regulator YP_007234291.1 791526 D 1042417 CDS YP_007234292.1 431807394 14293565 792087..793571 1 NC_019908.1 COG0642 Signal transduction histidine kinase; two-component system histidine kinase 793571 14293565 BPP43_03725 Brachyspira pilosicoli P43/6/78 two-component system histidine kinase YP_007234292.1 792087 D 1042417 CDS YP_007234293.1 431807395 14293566 complement(793574..794044) 1 NC_019908.1 hypothetical protein 794044 14293566 BPP43_03730 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234293.1 793574 R 1042417 CDS YP_007234294.1 431807396 14293567 complement(794041..794595) 1 NC_019908.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor RpoE 794595 14293567 BPP43_03735 Brachyspira pilosicoli P43/6/78 RNA polymerase sigma factor RpoE YP_007234294.1 794041 R 1042417 CDS YP_007234295.1 431807397 14293568 complement(794605..795054) 1 NC_019908.1 hypothetical protein 795054 14293568 BPP43_03740 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234295.1 794605 R 1042417 CDS YP_007234296.1 431807398 14293569 795259..796290 1 NC_019908.1 hypothetical protein 796290 14293569 BPP43_03745 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234296.1 795259 D 1042417 CDS YP_007234297.1 431807399 14293570 796352..797074 1 NC_019908.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; dolichyl-phosphate beta-D-mannosyltransferase 797074 14293570 BPP43_03750 Brachyspira pilosicoli P43/6/78 dolichyl-phosphate beta-D-mannosyltransferase YP_007234297.1 796352 D 1042417 CDS YP_007234298.1 431807400 14293571 complement(797082..798350) 1 NC_019908.1 COG0128 5-enolpyruvylshikimate-3-phosphate synthase; 3-phosphoshikimate 1-carboxyvinyltransferase 798350 14293571 BPP43_03755 Brachyspira pilosicoli P43/6/78 3-phosphoshikimate 1-carboxyvinyltransferase YP_007234298.1 797082 R 1042417 CDS YP_007234299.1 431807401 14293572 complement(798368..799327) 1 NC_019908.1 COG0552 Signal recognition particle GTPase; signal recognition particle receptor FtsY 799327 14293572 BPP43_03760 Brachyspira pilosicoli P43/6/78 signal recognition particle receptor FtsY YP_007234299.1 798368 R 1042417 CDS YP_007234300.1 431807402 14293573 799505..800785 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 800785 14293573 BPP43_03765 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234300.1 799505 D 1042417 CDS YP_007234301.1 431807403 14293574 complement(800782..802032) 1 NC_019908.1 COG0124 Histidyl-tRNA synthetase; histidyl-tRNA synthetase class IIa 802032 14293574 BPP43_03770 Brachyspira pilosicoli P43/6/78 histidyl-tRNA synthetase class IIa YP_007234301.1 800782 R 1042417 CDS YP_007234302.1 431807404 14293575 complement(802071..803351) 1 NC_019908.1 protein kinase 803351 14293575 BPP43_03775 Brachyspira pilosicoli P43/6/78 protein kinase YP_007234302.1 802071 R 1042417 CDS YP_007234303.1 431807405 14293576 803553..805367 1 NC_019908.1 COG1649 Uncharacterized protein conserved in bacteria; hypothetical protein 805367 14293576 BPP43_03780 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234303.1 803553 D 1042417 CDS YP_007234304.1 431807406 14293577 805450..806595 1 NC_019908.1 COG2385 Sporulation protein and related proteins; lipoprotein 806595 14293577 BPP43_03785 Brachyspira pilosicoli P43/6/78 lipoprotein YP_007234304.1 805450 D 1042417 CDS YP_007234305.1 431807407 14293578 807065..807274 1 NC_019908.1 hypothetical protein 807274 14293578 BPP43_03790 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234305.1 807065 D 1042417 CDS YP_007234306.1 431807408 14293579 complement(807489..808652) 1 NC_019908.1 COG0582 Integrase; bacteriophage-associated integrase XerDC family protein 808652 14293579 BPP43_03795 Brachyspira pilosicoli P43/6/78 bacteriophage-associated integrase XerDC family protein YP_007234306.1 807489 R 1042417 CDS YP_007234307.1 431807409 14293580 complement(809304..809528) 1 NC_019908.1 hypothetical protein 809528 14293580 BPP43_03800 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234307.1 809304 R 1042417 CDS YP_007234308.1 431807410 14293581 complement(809554..809763) 1 NC_019908.1 hypothetical protein 809763 14293581 BPP43_03805 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234308.1 809554 R 1042417 CDS YP_007234309.1 431807411 14293582 complement(809775..811583) 1 NC_019908.1 hypothetical protein 811583 14293582 BPP43_03810 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234309.1 809775 R 1042417 CDS YP_007234310.1 431807412 14293583 complement(811621..812157) 1 NC_019908.1 VSH-1 phage protein-like protein 812157 14293583 BPP43_03815 Brachyspira pilosicoli P43/6/78 VSH-1 phage protein-like protein YP_007234310.1 811621 R 1042417 CDS YP_007234311.1 431807413 14293584 complement(812182..812607) 1 NC_019908.1 COG0419 ATPase involved in DNA repair; hypothetical protein 812607 14293584 BPP43_03820 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234311.1 812182 R 1042417 CDS YP_007234312.1 431807414 14293585 complement(812628..813203) 1 NC_019908.1 COG3179 Predicted chitinase; glycoside hydrolase family protein 813203 14293585 BPP43_03825 Brachyspira pilosicoli P43/6/78 glycoside hydrolase family protein YP_007234312.1 812628 R 1042417 CDS YP_007234313.1 431807415 14293586 complement(813606..814001) 1 NC_019908.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; RNA polymerase domain-containing protein 814001 14293586 BPP43_03830 Brachyspira pilosicoli P43/6/78 RNA polymerase domain-containing protein YP_007234313.1 813606 R 1042417 CDS YP_007234314.1 431807416 14293587 complement(813998..814195) 1 NC_019908.1 hypothetical protein 814195 14293587 BPP43_03835 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234314.1 813998 R 1042417 CDS YP_007234315.1 431807417 14293588 complement(814213..816132) 1 NC_019908.1 hypothetical protein 816132 14293588 BPP43_03840 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234315.1 814213 R 1042417 CDS YP_007234316.1 431807418 14293589 complement(816142..817230) 1 NC_019908.1 hypothetical protein 817230 14293589 BPP43_03845 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234316.1 816142 R 1042417 CDS YP_007234317.1 431807419 14293590 complement(817230..817682) 1 NC_019908.1 hypothetical protein 817682 14293590 BPP43_03850 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234317.1 817230 R 1042417 CDS YP_007234318.1 431807420 14293591 complement(818500..821973) 1 NC_019908.1 COG5283 Phage-related tail protein; phage tail tape measure protein 821973 14293591 BPP43_03865 Brachyspira pilosicoli P43/6/78 phage tail tape measure protein YP_007234318.1 818500 R 1042417 CDS YP_007234319.1 431807421 14293592 complement(822001..822174) 1 NC_019908.1 hypothetical protein 822174 14293592 BPP43_03870 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234319.1 822001 R 1042417 CDS YP_007234320.1 431807422 14293593 complement(822273..822590) 1 NC_019908.1 hypothetical protein 822590 14293593 BPP43_03875 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234320.1 822273 R 1042417 CDS YP_007234321.1 431807423 14293594 complement(822615..823703) 1 NC_019908.1 hypothetical protein 823703 14293594 BPP43_03880 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234321.1 822615 R 1042417 CDS YP_007234322.1 431807424 14293595 complement(823715..824083) 1 NC_019908.1 hypothetical protein 824083 14293595 BPP43_03885 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234322.1 823715 R 1042417 CDS YP_007234323.1 431807425 14293596 complement(824080..824550) 1 NC_019908.1 hypothetical protein 824550 14293596 BPP43_03890 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234323.1 824080 R 1042417 CDS YP_007234324.1 431807426 14293597 complement(824552..824893) 1 NC_019908.1 hypothetical protein 824893 14293597 BPP43_03895 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234324.1 824552 R 1042417 CDS YP_007234325.1 431807427 14293598 complement(824890..825255) 1 NC_019908.1 DNA packaging phage QLRG family protein 825255 14293598 BPP43_03900 Brachyspira pilosicoli P43/6/78 DNA packaging phage QLRG family protein YP_007234325.1 824890 R 1042417 CDS YP_007234326.1 431807428 14293599 complement(825282..826583) 1 NC_019908.1 COG4653 Predicted phage phi-C31 gp36 major capsid-like protein; phage major capsid protein-like protein 826583 14293599 BPP43_03905 Brachyspira pilosicoli P43/6/78 phage major capsid protein-like protein YP_007234326.1 825282 R 1042417 CDS YP_007234327.1 431807429 14293600 complement(826619..827215) 1 NC_019908.1 COG3740 Phage head maturation protease; phage prohead protease 827215 14293600 BPP43_03910 Brachyspira pilosicoli P43/6/78 phage prohead protease YP_007234327.1 826619 R 1042417 CDS YP_007234328.1 431807430 14293601 complement(827199..828521) 1 NC_019908.1 COG4695 Phage-related protein; phage portal protein 828521 14293601 BPP43_03915 Brachyspira pilosicoli P43/6/78 phage portal protein YP_007234328.1 827199 R 1042417 CDS YP_007234329.1 431807431 14293602 complement(828593..829504) 1 NC_019908.1 COG0863 DNA modification methylase; DNA methylase N-4/N-6 domain-containing protein 829504 14293602 BPP43_03920 Brachyspira pilosicoli P43/6/78 DNA methylase N-4/N-6 domain-containing protein YP_007234329.1 828593 R 1042417 CDS YP_007234330.1 431807432 14293603 829602..830030 1 NC_019908.1 COG3747 Phage terminase, small subunit; phage terminase large subunit 830030 14293603 BPP43_03925 Brachyspira pilosicoli P43/6/78 phage terminase large subunit YP_007234330.1 829602 D 1042417 CDS YP_007234331.1 431807433 14293604 830036..831808 1 NC_019908.1 COG4626 Phage terminase-like protein, large subunit; phage terminase large subunit 831808 14293604 BPP43_03930 Brachyspira pilosicoli P43/6/78 phage terminase large subunit YP_007234331.1 830036 D 1042417 CDS YP_007234332.1 431807434 14293605 complement(831866..832264) 1 NC_019908.1 hypothetical protein 832264 14293605 BPP43_03935 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234332.1 831866 R 1042417 CDS YP_007234333.1 431807435 14293606 complement(832430..832819) 1 NC_019908.1 hypothetical protein 832819 14293606 BPP43_03940 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234333.1 832430 R 1042417 CDS YP_007234334.1 431807436 14293607 complement(832881..833087) 1 NC_019908.1 hypothetical protein 833087 14293607 BPP43_03945 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234334.1 832881 R 1042417 CDS YP_007234335.1 431807437 14293608 complement(833197..833403) 1 NC_019908.1 hypothetical protein 833403 14293608 BPP43_03950 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234335.1 833197 R 1042417 CDS YP_007234336.1 431807438 14293609 833641..833847 1 NC_019908.1 hypothetical protein 833847 14293609 BPP43_03955 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234336.1 833641 D 1042417 CDS YP_007234337.1 431807439 14293610 complement(834057..834806) 1 NC_019908.1 hypothetical protein 834806 14293610 BPP43_03960 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234337.1 834057 R 1042417 CDS YP_007234338.1 431807440 14293611 complement(834936..835934) 1 NC_019908.1 hypothetical protein 835934 14293611 BPP43_03965 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234338.1 834936 R 1042417 CDS YP_007234339.1 431807441 14293612 complement(835968..837983) 1 NC_019908.1 COG0323 DNA mismatch repair enzyme (predicted ATPase); hypothetical protein 837983 14293612 BPP43_03970 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234339.1 835968 R 1042417 CDS YP_007234340.1 431807442 14293613 complement(838064..838303) 1 NC_019908.1 hypothetical protein 838303 14293613 BPP43_03975 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234340.1 838064 R 1042417 CDS YP_007234341.1 431807443 14293614 838683..839783 1 NC_019908.1 hypothetical protein 839783 14293614 BPP43_03980 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234341.1 838683 D 1042417 CDS YP_007234342.1 431807444 14293615 complement(839835..840764) 1 NC_019908.1 COG4973 Site-specific recombinase XerC; site-specific recombinase 840764 14293615 BPP43_03985 Brachyspira pilosicoli P43/6/78 site-specific recombinase YP_007234342.1 839835 R 1042417 CDS YP_007234343.1 431807445 14293616 complement(840886..841050) 1 NC_019908.1 hypothetical protein 841050 14293616 BPP43_03990 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234343.1 840886 R 1042417 CDS YP_007234344.1 431807446 14293617 complement(841096..841581) 1 NC_019908.1 hypothetical protein 841581 14293617 BPP43_03995 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234344.1 841096 R 1042417 CDS YP_007234345.1 431807447 14293618 complement(841574..841786) 1 NC_019908.1 hypothetical protein 841786 14293618 BPP43_04000 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234345.1 841574 R 1042417 CDS YP_007234346.1 431807448 14293619 complement(841860..842300) 1 NC_019908.1 hypothetical protein 842300 14293619 BPP43_04005 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234346.1 841860 R 1042417 CDS YP_007234347.1 431807449 14293620 complement(842297..842446) 1 NC_019908.1 hypothetical protein 842446 14293620 BPP43_04010 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234347.1 842297 R 1042417 CDS YP_007234348.1 431807450 14293621 complement(842461..842706) 1 NC_019908.1 hypothetical protein 842706 14293621 BPP43_04015 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234348.1 842461 R 1042417 CDS YP_007234349.1 431807451 14293622 complement(842718..842987) 1 NC_019908.1 COG1403 Restriction endonuclease; HNH endonuclease 842987 14293622 BPP43_04020 Brachyspira pilosicoli P43/6/78 HNH endonuclease YP_007234349.1 842718 R 1042417 CDS YP_007234350.1 431807452 14293623 complement(843045..843323) 1 NC_019908.1 hypothetical protein 843323 14293623 BPP43_04025 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234350.1 843045 R 1042417 CDS YP_007234351.1 431807453 14293624 complement(843326..843640) 1 NC_019908.1 COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); hypothetical protein 843640 14293624 BPP43_04030 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234351.1 843326 R 1042417 CDS YP_007234352.1 431807454 14293625 complement(843709..844569) 1 NC_019908.1 COG0593 ATPase involved in DNA replication initiation; DNA replication protein DnaC-like protein 844569 14293625 BPP43_04035 Brachyspira pilosicoli P43/6/78 DNA replication protein DnaC-like protein YP_007234352.1 843709 R 1042417 CDS YP_007234353.1 431807455 14293626 complement(844695..845486) 1 NC_019908.1 hypothetical protein 845486 14293626 BPP43_04040 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234353.1 844695 R 1042417 CDS YP_007234354.1 431807456 14293627 complement(845476..845844) 1 NC_019908.1 hypothetical protein 845844 14293627 BPP43_04045 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234354.1 845476 R 1042417 CDS YP_007234355.1 431807457 14293628 complement(846538..847905) 1 NC_019908.1 COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase YwdH 847905 14293628 BPP43_04050 Brachyspira pilosicoli P43/6/78 aldehyde dehydrogenase YwdH YP_007234355.1 846538 R 1042417 CDS YP_007234356.1 431807458 14293629 complement(848183..848881) 1 NC_019908.1 COG0813 Purine-nucleoside phosphorylase; purine nucleoside phosphorylase 848881 14293629 BPP43_04055 Brachyspira pilosicoli P43/6/78 purine nucleoside phosphorylase YP_007234356.1 848183 R 1042417 CDS YP_007234357.1 431807459 14293630 complement(848943..849713) 1 NC_019908.1 COG0647 Predicted sugar phosphatases of the HAD superfamily; N-acetylglucosamine metabolism protein 849713 14293630 BPP43_04060 Brachyspira pilosicoli P43/6/78 N-acetylglucosamine metabolism protein YP_007234357.1 848943 R 1042417 CDS YP_007234358.1 431807460 14293631 complement(849744..851426) 1 NC_019908.1 COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold; metal-dependent amidohydrolase 851426 14293631 BPP43_04065 Brachyspira pilosicoli P43/6/78 metal-dependent amidohydrolase YP_007234358.1 849744 R 1042417 CDS YP_007234359.1 431807461 14293632 complement(851733..852233) 1 NC_019908.1 COG0262 Dihydrofolate reductase; dihydrofolate reductase 852233 14293632 BPP43_04070 Brachyspira pilosicoli P43/6/78 dihydrofolate reductase YP_007234359.1 851733 R 1042417 CDS YP_007234360.1 431807462 14293633 complement(852230..853030) 1 NC_019908.1 COG0207 Thymidylate synthase; thymidylate synthase 853030 14293633 BPP43_04075 Brachyspira pilosicoli P43/6/78 thymidylate synthase YP_007234360.1 852230 R 1042417 CDS YP_007234361.1 431807463 14293634 853268..854539 1 NC_019908.1 COG1253 Hemolysins and related proteins containing CBS domains; hemolysin 854539 14293634 BPP43_04080 Brachyspira pilosicoli P43/6/78 hemolysin YP_007234361.1 853268 D 1042417 CDS YP_007234362.1 431807464 14293635 854633..854800 1 NC_019908.1 COG1145 Ferredoxin; ferredoxin, 4Fe-4S 854800 14293635 BPP43_04085 Brachyspira pilosicoli P43/6/78 ferredoxin, 4Fe-4S YP_007234362.1 854633 D 1042417 CDS YP_007234363.1 431807465 14293636 854835..855656 1 NC_019908.1 COG1381 Recombinational DNA repair protein (RecF pathway); DNA repair protein RecO 855656 14293636 BPP43_04090 Brachyspira pilosicoli P43/6/78 DNA repair protein RecO YP_007234363.1 854835 D 1042417 CDS YP_007234364.1 431807466 14293637 complement(855633..856307) 1 NC_019908.1 COG0546 Predicted phosphatases; phosphatase, HAD family protein 856307 14293637 BPP43_04095 Brachyspira pilosicoli P43/6/78 phosphatase, HAD family protein YP_007234364.1 855633 R 1042417 CDS YP_007234365.1 431807467 14293638 complement(857301..859268) 1 NC_019908.1 COG1315 Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain; polymerase 859268 14293638 BPP43_04110 Brachyspira pilosicoli P43/6/78 polymerase YP_007234365.1 857301 R 1042417 CDS YP_007234366.1 431807468 14293639 complement(859282..860094) 1 NC_019908.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; RNA polymerase sigma factor WhiG 860094 14293639 BPP43_04115 Brachyspira pilosicoli P43/6/78 RNA polymerase sigma factor WhiG YP_007234366.1 859282 R 1042417 CDS YP_007234367.1 431807469 14293640 complement(860124..860795) 1 NC_019908.1 hypothetical protein 860795 14293640 BPP43_04120 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234367.1 860124 R 1042417 CDS YP_007234368.1 431807470 14293641 complement(860821..861699) 1 NC_019908.1 COG0455 ATPases involved in chromosome partitioning; flagellar synthesis regulator FleN 861699 14293641 BPP43_04125 Brachyspira pilosicoli P43/6/78 flagellar synthesis regulator FleN YP_007234368.1 860821 R 1042417 CDS YP_007234369.1 431807471 14293642 complement(861734..863542) 1 NC_019908.1 COG1419 Flagellar GTP-binding protein; flagellar biosynthesis regulator FlhF 863542 14293642 BPP43_04130 Brachyspira pilosicoli P43/6/78 flagellar biosynthesis regulator FlhF YP_007234369.1 861734 R 1042417 CDS YP_007234370.1 431807472 14293643 complement(863561..863734) 1 NC_019908.1 hypothetical protein 863734 14293643 BPP43_04135 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234370.1 863561 R 1042417 CDS YP_007234371.1 431807473 14293644 complement(863778..865898) 1 NC_019908.1 COG1298 Flagellar biosynthesis pathway, component FlhA; flagellar biosynthesis protein FlgA 865898 14293644 BPP43_04140 Brachyspira pilosicoli P43/6/78 flagellar biosynthesis protein FlgA YP_007234371.1 863778 R 1042417 CDS YP_007234372.1 431807474 14293645 complement(865912..867126) 1 NC_019908.1 COG1377 Flagellar biosynthesis pathway, component FlhB; flagellar biosynthesis protein FlhB 867126 14293645 BPP43_04145 Brachyspira pilosicoli P43/6/78 flagellar biosynthesis protein FlhB YP_007234372.1 865912 R 1042417 CDS YP_007234373.1 431807475 14293646 complement(867123..867926) 1 NC_019908.1 COG1684 Flagellar biosynthesis pathway, component FliR; flagellar biosynthesis protein FliR 867926 14293646 BPP43_04150 Brachyspira pilosicoli P43/6/78 flagellar biosynthesis protein FliR YP_007234373.1 867123 R 1042417 CDS YP_007234374.1 431807476 14293647 complement(867951..868220) 1 NC_019908.1 COG1987 Flagellar biosynthesis pathway, component FliQ; flagellar protein FliO/FliZ 868220 14293647 BPP43_04155 Brachyspira pilosicoli P43/6/78 flagellar protein FliO/FliZ YP_007234374.1 867951 R 1042417 CDS YP_007234375.1 431807477 14293648 complement(868245..869027) 1 NC_019908.1 COG1338 Flagellar biosynthesis pathway, component FliP; flagellar biosynthesis protein FliP 869027 14293648 BPP43_04160 Brachyspira pilosicoli P43/6/78 flagellar biosynthesis protein FliP YP_007234375.1 868245 R 1042417 CDS YP_007234376.1 431807478 14293649 complement(869161..869658) 1 NC_019908.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; ribosomal-protein-alanine acetyltransferase 869658 14293649 BPP43_04165 Brachyspira pilosicoli P43/6/78 ribosomal-protein-alanine acetyltransferase YP_007234376.1 869161 R 1042417 CDS YP_007234377.1 431807479 14293650 869858..870625 1 NC_019908.1 COG0730 Predicted permeases; transporter membrane 870625 14293650 BPP43_04170 Brachyspira pilosicoli P43/6/78 transporter membrane YP_007234377.1 869858 D 1042417 CDS YP_007234378.1 431807480 14293651 871459..872262 1 NC_019908.1 COG0775 Nucleoside phosphorylase; hypothetical protein 872262 14293651 BPP43_04175 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234378.1 871459 D 1042417 CDS YP_007234379.1 431807481 14293652 complement(872259..873890) 1 NC_019908.1 COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; aspartate oxidase 873890 14293652 BPP43_04180 Brachyspira pilosicoli P43/6/78 aspartate oxidase YP_007234379.1 872259 R 1042417 CDS YP_007234380.1 431807482 14293653 874052..874765 1 NC_019908.1 COG0775 Nucleoside phosphorylase; 5'-methylthioadenosine nucleosidase 874765 14293653 BPP43_04185 Brachyspira pilosicoli P43/6/78 5'-methylthioadenosine nucleosidase YP_007234380.1 874052 D 1042417 CDS YP_007234381.1 431807483 14293654 874848..876602 1 NC_019908.1 COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); phosphoenolpyruvate protein kinase/PTS system transporter subunit EI 876602 14293654 BPP43_04190 Brachyspira pilosicoli P43/6/78 phosphoenolpyruvate protein kinase/PTS system transporter subunit EI YP_007234381.1 874848 D 1042417 CDS YP_007234382.1 431807484 14293655 876604..878061 1 NC_019908.1 hypothetical protein 878061 14293655 BPP43_04195 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234382.1 876604 D 1042417 CDS YP_007234383.1 431807485 14293656 complement(878146..879147) 1 NC_019908.1 COG0280 Phosphotransacetylase; phosphotransacetylase 879147 14293656 BPP43_04200 Brachyspira pilosicoli P43/6/78 phosphotransacetylase YP_007234383.1 878146 R 1042417 CDS YP_007234384.1 431807486 14293657 complement(880687..882720) 1 NC_019908.1 COG3225 ABC-type uncharacterized transport system involved in gliding motility, auxiliary component; ABC transporter protein 882720 14293657 BPP43_04215 Brachyspira pilosicoli P43/6/78 ABC transporter protein YP_007234384.1 880687 R 1042417 CDS YP_007234385.1 431807487 14293659 882999..883715 1 NC_019908.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; pseudouridine synthase 883715 14293659 BPP43_04220 Brachyspira pilosicoli P43/6/78 pseudouridine synthase YP_007234385.1 882999 D 1042417 CDS YP_007234386.1 431807488 14293660 883788..884840 1 NC_019908.1 COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family; methylthioribose-1-phosphate isomerase 884840 mtnA 14293660 mtnA Brachyspira pilosicoli P43/6/78 methylthioribose-1-phosphate isomerase YP_007234386.1 883788 D 1042417 CDS YP_007234387.1 431807489 14293661 885242..885775 1 NC_019908.1 hypothetical protein 885775 14293661 BPP43_04230 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234387.1 885242 D 1042417 CDS YP_007234388.1 431807490 14293662 complement(885780..886466) 1 NC_019908.1 COG0325 Predicted enzyme with a TIM-barrel fold; proline synthetase associated protein 886466 14293662 BPP43_04235 Brachyspira pilosicoli P43/6/78 proline synthetase associated protein YP_007234388.1 885780 R 1042417 CDS YP_007234389.1 431807491 14293663 886611..887057 1 NC_019908.1 COG0802 Predicted ATPase or kinase; nucleotide-binding protein 887057 14293663 BPP43_04240 Brachyspira pilosicoli P43/6/78 nucleotide-binding protein YP_007234389.1 886611 D 1042417 CDS YP_007234390.1 431807492 14293664 887054..888025 1 NC_019908.1 hypothetical protein 888025 14293664 BPP43_04245 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234390.1 887054 D 1042417 CDS YP_007234391.1 431807493 14293665 888045..889433 1 NC_019908.1 COG0486 Predicted GTPase; tRNA-modification GTPase TrmE 889433 14293665 BPP43_04250 Brachyspira pilosicoli P43/6/78 tRNA-modification GTPase TrmE YP_007234391.1 888045 D 1042417 CDS YP_007234392.1 431807494 14293666 complement(889844..890797) 1 NC_019908.1 COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog; membrane dipeptidase 890797 14293666 BPP43_04255 Brachyspira pilosicoli P43/6/78 membrane dipeptidase YP_007234392.1 889844 R 1042417 CDS YP_007234393.1 431807495 14293667 891129..893666 1 NC_019908.1 COG2003 DNA repair proteins; helicase c2 893666 14293667 BPP43_04260 Brachyspira pilosicoli P43/6/78 helicase c2 YP_007234393.1 891129 D 1042417 CDS YP_007234394.1 431807496 14293668 893962..894147 1 NC_019908.1 hypothetical protein 894147 14293668 BPP43_04265 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234394.1 893962 D 1042417 CDS YP_007234395.1 431807497 14293669 894137..897457 1 NC_019908.1 molybdate metabolism regulator 897457 14293669 BPP43_04270 Brachyspira pilosicoli P43/6/78 molybdate metabolism regulator YP_007234395.1 894137 D 1042417 CDS YP_007234396.1 431807498 14293670 complement(897581..898561) 1 NC_019908.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 898561 14293670 BPP43_04275 Brachyspira pilosicoli P43/6/78 oxidoreductase domain-containing protein YP_007234396.1 897581 R 1042417 CDS YP_007234397.1 431807499 14293671 complement(898751..899752) 1 NC_019908.1 COG0276 Protoheme ferro-lyase (ferrochelatase); ferrochelatase 899752 14293671 BPP43_04280 Brachyspira pilosicoli P43/6/78 ferrochelatase YP_007234397.1 898751 R 1042417 CDS YP_007234398.1 431807500 14293672 complement(899959..900897) 1 NC_019908.1 periplasmic ATP/GTP-binding protein 900897 14293672 BPP43_04285 Brachyspira pilosicoli P43/6/78 periplasmic ATP/GTP-binding protein YP_007234398.1 899959 R 1042417 CDS YP_007234399.1 431807501 14293673 901056..901493 1 NC_019908.1 COG1959 Predicted transcriptional regulator; Rrf2 family transcriptional regulator 901493 14293673 BPP43_04290 Brachyspira pilosicoli P43/6/78 Rrf2 family transcriptional regulator YP_007234399.1 901056 D 1042417 CDS YP_007234400.1 431807502 14293674 902300..903106 1 NC_019908.1 COG1145 Ferredoxin; 4Fe-4S ferredoxin 903106 14293674 BPP43_04305 Brachyspira pilosicoli P43/6/78 4Fe-4S ferredoxin YP_007234400.1 902300 D 1042417 CDS YP_007234401.1 431807503 14293675 903212..904366 1 NC_019908.1 COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 904366 14293675 BPP43_04310 Brachyspira pilosicoli P43/6/78 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_007234401.1 903212 D 1042417 CDS YP_007234402.1 431807504 14293676 904375..905535 1 NC_019908.1 COG2607 Predicted ATPase (AAA+ superfamily); hypothetical protein 905535 14293676 BPP43_04315 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234402.1 904375 D 1042417 CDS YP_007234403.1 431807505 14293677 complement(905538..907112) 1 NC_019908.1 hypothetical protein 907112 14293677 BPP43_04320 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234403.1 905538 R 1042417 CDS YP_007234404.1 431807506 14293678 complement(910727..911710) 1 NC_019908.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; binding-protein-dependent transport system inner membrane protein 911710 14293678 BPP43_04355 Brachyspira pilosicoli P43/6/78 binding-protein-dependent transport system inner membrane protein YP_007234404.1 910727 R 1042417 CDS YP_007234405.1 431807507 14293679 complement(911728..912648) 1 NC_019908.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; binding-protein-dependent transport system inner membrane protein 912648 14293679 BPP43_04360 Brachyspira pilosicoli P43/6/78 binding-protein-dependent transport system inner membrane protein YP_007234405.1 911728 R 1042417 CDS YP_007234406.1 431807508 14293680 complement(912764..916411) 1 NC_019908.1 COG0587 DNA polymerase III, alpha subunit; DNA polymerase III subunit alpha 916411 14293680 BPP43_04365 Brachyspira pilosicoli P43/6/78 DNA polymerase III subunit alpha YP_007234406.1 912764 R 1042417 CDS YP_007234407.1 431807509 14293682 complement(916813..917904) 1 NC_019908.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; serine phosphatase RsbU/regulator of sigma subunit 917904 14293682 BPP43_04370 Brachyspira pilosicoli P43/6/78 serine phosphatase RsbU/regulator of sigma subunit YP_007234407.1 916813 R 1042417 CDS YP_007234408.1 431807510 14293683 complement(917982..918350) 1 NC_019908.1 COG3169 Uncharacterized protein conserved in bacteria; hypothetical protein 918350 14293683 BPP43_04375 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234408.1 917982 R 1042417 CDS YP_007234409.1 431807511 14293684 complement(918407..919336) 1 NC_019908.1 COG0812 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylmuramate dehydrogenase 919336 14293684 BPP43_04380 Brachyspira pilosicoli P43/6/78 UDP-N-acetylmuramate dehydrogenase YP_007234409.1 918407 R 1042417 CDS YP_007234410.1 431807512 14293685 complement(919311..920693) 1 NC_019908.1 COG0773 UDP-N-acetylmuramate-alanine ligase; UDP-N-acetylmuramate alanine ligase 920693 14293685 BPP43_04385 Brachyspira pilosicoli P43/6/78 UDP-N-acetylmuramate alanine ligase YP_007234410.1 919311 R 1042417 CDS YP_007234411.1 431807513 14293686 complement(920773..921228) 1 NC_019908.1 COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase; ADP-heptose synthase 921228 14293686 BPP43_04390 Brachyspira pilosicoli P43/6/78 ADP-heptose synthase YP_007234411.1 920773 R 1042417 CDS YP_007234412.1 431807514 14293687 complement(921338..922744) 1 NC_019908.1 COG0786 Na+/glutamate symporter; sodium/glutamate symporter 922744 14293687 BPP43_04395 Brachyspira pilosicoli P43/6/78 sodium/glutamate symporter YP_007234412.1 921338 R 1042417 CDS YP_007234413.1 431807515 14293688 complement(922741..923562) 1 NC_019908.1 COG2949 Uncharacterized membrane protein; sanA protein 923562 14293688 BPP43_04400 Brachyspira pilosicoli P43/6/78 sanA protein YP_007234413.1 922741 R 1042417 CDS YP_007234414.1 431807516 14293689 923673..923915 1 NC_019908.1 hypothetical protein 923915 14293689 BPP43_04405 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234414.1 923673 D 1042417 CDS YP_007234415.1 431807517 14293690 928225..929148 1 NC_019908.1 COG4974 Site-specific recombinase XerD; tyrosine recombinase XerD 929148 14293690 BPP43_04430 Brachyspira pilosicoli P43/6/78 tyrosine recombinase XerD YP_007234415.1 928225 D 1042417 CDS YP_007234416.1 431807518 14293691 929299..930714 1 NC_019908.1 COG0760 Parvulin-like peptidyl-prolyl isomerase; hypothetical protein 930714 14293691 BPP43_04435 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234416.1 929299 D 1042417 CDS YP_007234417.1 431807519 14293692 930729..931049 1 NC_019908.1 hypothetical protein 931049 14293692 BPP43_04440 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234417.1 930729 D 1042417 CDS YP_007234418.1 431807520 14293693 complement(931584..932285) 1 NC_019908.1 hypothetical protein 932285 14293693 BPP43_04445 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234418.1 931584 R 1042417 CDS YP_007234419.1 431807521 14293694 complement(932441..935035) 1 NC_019908.1 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; DNA gyrase subunit A 935035 14293694 BPP43_04450 Brachyspira pilosicoli P43/6/78 DNA gyrase subunit A YP_007234419.1 932441 R 1042417 CDS YP_007234420.1 431807522 14293696 935324..937219 1 NC_019908.1 COG0768 Cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein 3 937219 14293696 BPP43_04455 Brachyspira pilosicoli P43/6/78 penicillin-binding protein 3 YP_007234420.1 935324 D 1042417 CDS YP_007234421.1 431807523 14293697 937242..938144 1 NC_019908.1 COG0524 Sugar kinases, ribokinase family; PfkB family carbohydrate kinase 938144 14293697 BPP43_04460 Brachyspira pilosicoli P43/6/78 PfkB family carbohydrate kinase YP_007234421.1 937242 D 1042417 CDS YP_007234422.1 431807524 14293698 complement(938141..938614) 1 NC_019908.1 hypothetical protein 938614 14293698 BPP43_04465 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234422.1 938141 R 1042417 CDS YP_007234423.1 431807525 14293699 complement(938642..939805) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 939805 14293699 BPP43_04470 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234423.1 938642 R 1042417 CDS YP_007234424.1 431807526 14293700 complement(939841..940446) 1 NC_019908.1 COG1259 Uncharacterized conserved protein; hypothetical protein 940446 14293700 BPP43_04475 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234424.1 939841 R 1042417 CDS YP_007234425.1 431807527 14293701 complement(940517..940750) 1 NC_019908.1 hypothetical protein 940750 14293701 BPP43_04480 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234425.1 940517 R 1042417 CDS YP_007234426.1 431807528 14293702 complement(940770..941552) 1 NC_019908.1 COG0340 Biotin-(acetyl-CoA carboxylase) ligase; hypothetical protein 941552 14293702 BPP43_04485 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234426.1 940770 R 1042417 CDS YP_007234427.1 431807529 14293703 941673..942152 1 NC_019908.1 COG0835 Chemotaxis signal transduction protein; purine-binding chemotaxis protein 942152 14293703 BPP43_04490 Brachyspira pilosicoli P43/6/78 purine-binding chemotaxis protein YP_007234427.1 941673 D 1042417 CDS YP_007234428.1 431807530 14293704 942158..942526 1 NC_019908.1 COG0858 Ribosome-binding factor A; ribosome-binding factor A 942526 14293704 BPP43_04495 Brachyspira pilosicoli P43/6/78 ribosome-binding factor A YP_007234428.1 942158 D 1042417 CDS YP_007234429.1 431807531 14293705 943567..944058 1 NC_019908.1 COG0328 Ribonuclease HI; ribonuclease H 944058 14293705 BPP43_04510 Brachyspira pilosicoli P43/6/78 ribonuclease H YP_007234429.1 943567 D 1042417 CDS YP_007234430.1 431807532 14293706 944228..945235 1 NC_019908.1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; cAMP-binding protein 945235 14293706 BPP43_04515 Brachyspira pilosicoli P43/6/78 cAMP-binding protein YP_007234430.1 944228 D 1042417 CDS YP_007234431.1 431807533 14293707 945245..945874 1 NC_019908.1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; cAMP-binding protein regulatory protein 945874 14293707 BPP43_04520 Brachyspira pilosicoli P43/6/78 cAMP-binding protein regulatory protein YP_007234431.1 945245 D 1042417 CDS YP_007234432.1 431807534 14293708 945970..946914 1 NC_019908.1 COG4866 Uncharacterized conserved protein; hypothetical protein 946914 14293708 BPP43_04525 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234432.1 945970 D 1042417 CDS YP_007234433.1 431807535 14293709 complement(946993..947853) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 947853 14293709 BPP43_04530 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234433.1 946993 R 1042417 CDS YP_007234434.1 431807536 14293710 complement(947877..949307) 1 NC_019908.1 fibronectin type III domain-containing protein 949307 14293710 BPP43_04535 Brachyspira pilosicoli P43/6/78 fibronectin type III domain-containing protein YP_007234434.1 947877 R 1042417 CDS YP_007234435.1 431807537 14293711 complement(949430..950113) 1 NC_019908.1 Ser/Thr protein phosphatase family protein 950113 14293711 BPP43_04540 Brachyspira pilosicoli P43/6/78 Ser/Thr protein phosphatase family protein YP_007234435.1 949430 R 1042417 CDS YP_007234436.1 431807538 14293712 950265..951368 1 NC_019908.1 hypothetical protein 951368 14293712 BPP43_04545 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234436.1 950265 D 1042417 CDS YP_007234437.1 431807539 14293713 951411..952103 1 NC_019908.1 hypothetical protein 952103 14293713 BPP43_04550 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234437.1 951411 D 1042417 CDS YP_007234438.1 431807540 14293714 952113..953036 1 NC_019908.1 COG2313 Uncharacterized enzyme involved in pigment biosynthesis; indigoidine synthase A family protein 953036 14293714 BPP43_04555 Brachyspira pilosicoli P43/6/78 indigoidine synthase A family protein YP_007234438.1 952113 D 1042417 CDS YP_007234439.1 431807541 14293715 953123..953371 1 NC_019908.1 COG2331 Uncharacterized protein conserved in bacteria; FmdB family regulatory protein 953371 14293715 BPP43_04560 Brachyspira pilosicoli P43/6/78 FmdB family regulatory protein YP_007234439.1 953123 D 1042417 CDS YP_007234440.1 431807542 14293716 953438..954466 1 NC_019908.1 COG0820 Predicted Fe-S-cluster redox enzyme; Fe-S cluster redox protein 954466 14293716 BPP43_04565 Brachyspira pilosicoli P43/6/78 Fe-S cluster redox protein YP_007234440.1 953438 D 1042417 CDS YP_007234441.1 431807543 14293717 complement(954483..955196) 1 NC_019908.1 COG1387 Histidinol phosphatase and related hydrolases of the PHP family; hydrolase 955196 14293717 BPP43_04570 Brachyspira pilosicoli P43/6/78 hydrolase YP_007234441.1 954483 R 1042417 CDS YP_007234442.1 431807544 14293718 complement(955212..955826) 1 NC_019908.1 cytidylate kinase 955826 14293718 BPP43_04575 Brachyspira pilosicoli P43/6/78 cytidylate kinase YP_007234442.1 955212 R 1042417 CDS YP_007234443.1 431807545 14293719 complement(955848..956279) 1 NC_019908.1 COG0716 Flavodoxins; hypothetical protein 956279 14293719 BPP43_04580 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234443.1 955848 R 1042417 CDS YP_007234444.1 431807546 14293720 complement(956276..956569) 1 NC_019908.1 hypothetical protein 956569 14293720 BPP43_04585 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234444.1 956276 R 1042417 CDS YP_007234445.1 431807547 14293721 complement(956638..957255) 1 NC_019908.1 hypothetical protein 957255 14293721 BPP43_04590 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234445.1 956638 R 1042417 CDS YP_007234446.1 431807548 14293722 complement(957435..959495) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 959495 14293722 BPP43_04595 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234446.1 957435 R 1042417 CDS YP_007234447.1 431807549 14293724 complement(959709..960362) 1 NC_019908.1 COG4912 Predicted DNA alkylation repair enzyme; DNA alkylation repair protein 960362 14293724 BPP43_04600 Brachyspira pilosicoli P43/6/78 DNA alkylation repair protein YP_007234447.1 959709 R 1042417 CDS YP_007234448.1 431807550 14293725 complement(960375..961832) 1 NC_019908.1 COG1032 Fe-S oxidoreductase; Fe-S-oxidoreductase 961832 14293725 BPP43_04605 Brachyspira pilosicoli P43/6/78 Fe-S-oxidoreductase YP_007234448.1 960375 R 1042417 CDS YP_007234449.1 431807551 14293726 complement(961993..962316) 1 NC_019908.1 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; cytosolic protein 962316 14293726 BPP43_04610 Brachyspira pilosicoli P43/6/78 cytosolic protein YP_007234449.1 961993 R 1042417 CDS YP_007234450.1 431807552 14293727 complement(962400..963287) 1 NC_019908.1 COG1408 Predicted phosphohydrolases; phosphohydrolase 963287 14293727 BPP43_04615 Brachyspira pilosicoli P43/6/78 phosphohydrolase YP_007234450.1 962400 R 1042417 CDS YP_007234451.1 431807553 14293728 complement(963284..965008) 1 NC_019908.1 COG4591 ABC-type transport system, involved in lipoprotein release, permease component; hypothetical protein 965008 14293728 BPP43_04620 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234451.1 963284 R 1042417 CDS YP_007234452.1 431807554 14293729 965282..966469 1 NC_019908.1 COG0192 S-adenosylmethionine synthetase; adenosylmethionine synthetase 966469 14293729 BPP43_04625 Brachyspira pilosicoli P43/6/78 adenosylmethionine synthetase YP_007234452.1 965282 D 1042417 CDS YP_007234453.1 431807555 14293730 966642..967337 1 NC_019908.1 COG0655 Multimeric flavodoxin WrbA; hypothetical protein 967337 14293730 BPP43_04630 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234453.1 966642 D 1042417 CDS YP_007234454.1 431807556 14293731 967425..968240 1 NC_019908.1 COG0775 Nucleoside phosphorylase; purine or other phosphorylase family 1 968240 14293731 BPP43_04635 Brachyspira pilosicoli P43/6/78 purine or other phosphorylase family 1 YP_007234454.1 967425 D 1042417 CDS YP_007234455.1 431807557 14293732 complement(968319..969170) 1 NC_019908.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; aldo/keto reductase 969170 14293732 BPP43_04640 Brachyspira pilosicoli P43/6/78 aldo/keto reductase YP_007234455.1 968319 R 1042417 CDS YP_007234456.1 431807558 14293733 969318..971051 1 NC_019908.1 hypothetical protein 971051 14293733 BPP43_04645 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234456.1 969318 D 1042417 CDS YP_007234457.1 431807559 14293734 971354..973933 1 NC_019908.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent Clp protease ATP-binding subunit ClpB 973933 14293734 BPP43_04650 Brachyspira pilosicoli P43/6/78 ATP-dependent Clp protease ATP-binding subunit ClpB YP_007234457.1 971354 D 1042417 CDS YP_007234458.1 431807560 14293735 complement(973975..974994) 1 NC_019908.1 COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; hypothetical protein 974994 14293735 BPP43_04655 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234458.1 973975 R 1042417 CDS YP_007234459.1 431807561 14293736 complement(975037..975627) 1 NC_019908.1 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; hypothetical protein 975627 14293736 BPP43_04660 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234459.1 975037 R 1042417 CDS YP_007234460.1 431807562 14293737 complement(975644..976903) 1 NC_019908.1 hypothetical protein 976903 14293737 BPP43_04665 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234460.1 975644 R 1042417 CDS YP_007234461.1 431807563 14293738 complement(976919..978670) 1 NC_019908.1 hypothetical protein 978670 14293738 BPP43_04670 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234461.1 976919 R 1042417 CDS YP_007234462.1 431807564 14293739 complement(978783..979577) 1 NC_019908.1 COG2145 Hydroxyethylthiazole kinase, sugar kinase family; hydroxyethylthiazole kinase 979577 14293739 BPP43_04675 Brachyspira pilosicoli P43/6/78 hydroxyethylthiazole kinase YP_007234462.1 978783 R 1042417 CDS YP_007234463.1 431807565 14293740 complement(979698..979868) 1 NC_019908.1 hypothetical protein 979868 14293740 BPP43_04680 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234463.1 979698 R 1042417 CDS YP_007234464.1 431807566 14293741 complement(980071..981423) 1 NC_019908.1 COG3314 Uncharacterized protein conserved in bacteria; nucleoside recognition domain-containing protein 981423 14293741 BPP43_04685 Brachyspira pilosicoli P43/6/78 nucleoside recognition domain-containing protein YP_007234464.1 980071 R 1042417 CDS YP_007234465.1 431807567 14293742 complement(981640..982179) 1 NC_019908.1 COG1592 Rubrerythrin; rubrerythrin 982179 14293742 BPP43_04690 Brachyspira pilosicoli P43/6/78 rubrerythrin YP_007234465.1 981640 R 1042417 CDS YP_007234466.1 431807568 14293743 982471..984324 1 NC_019908.1 COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily; metallo-beta-lactamase family protein 984324 14293743 BPP43_04695 Brachyspira pilosicoli P43/6/78 metallo-beta-lactamase family protein YP_007234466.1 982471 D 1042417 CDS YP_007234467.1 431807569 14293744 984207..985307 1 NC_019908.1 COG0616 Periplasmic serine proteases (ClpP class); periplasmic serine proteases ClpP class 985307 14293744 BPP43_04700 Brachyspira pilosicoli P43/6/78 periplasmic serine proteases ClpP class YP_007234467.1 984207 D 1042417 CDS YP_007234468.1 431807570 14293745 985309..985872 1 NC_019908.1 hypothetical protein 985872 14293745 BPP43_04705 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234468.1 985309 D 1042417 CDS YP_007234469.1 431807571 14293746 985882..987177 1 NC_019908.1 COG0795 Predicted permeases; YjgP/YjgQ family permease 987177 14293746 BPP43_04710 Brachyspira pilosicoli P43/6/78 YjgP/YjgQ family permease YP_007234469.1 985882 D 1042417 CDS YP_007234470.1 431807572 14293747 complement(987399..989465) 1 NC_019908.1 COG3391 Uncharacterized conserved protein; hypothetical protein 989465 14293747 BPP43_04715 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234470.1 987399 R 1042417 CDS YP_007234471.1 431807573 14293749 complement(989710..990426) 1 NC_019908.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic transglycosylase 990426 14293749 BPP43_04720 Brachyspira pilosicoli P43/6/78 lytic transglycosylase YP_007234471.1 989710 R 1042417 CDS YP_007234472.1 431807574 14293750 complement(990447..990884) 1 NC_019908.1 hypothetical protein 990884 14293750 BPP43_04725 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234472.1 990447 R 1042417 CDS YP_007234473.1 431807575 14293751 complement(990903..992372) 1 NC_019908.1 COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; flagellar biosynthesis/type III secretory pathway ATPase FliI 992372 14293751 BPP43_04730 Brachyspira pilosicoli P43/6/78 flagellar biosynthesis/type III secretory pathway ATPase FliI YP_007234473.1 990903 R 1042417 CDS YP_007234474.1 431807576 14293752 complement(992412..993311) 1 NC_019908.1 COG1317 Flagellar biosynthesis/type III secretory pathway protein; flagellar assembly protein H 993311 fliH 14293752 fliH Brachyspira pilosicoli P43/6/78 flagellar assembly protein H YP_007234474.1 992412 R 1042417 CDS YP_007234475.1 431807577 14293753 complement(993350..994384) 1 NC_019908.1 COG1536 Flagellar motor switch protein; flagellar motor switch protein G 994384 fliG 14293753 fliG Brachyspira pilosicoli P43/6/78 flagellar motor switch protein G YP_007234475.1 993350 R 1042417 CDS YP_007234476.1 431807578 14293754 complement(994429..996126) 1 NC_019908.1 COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein; flagellar MS-ring protein 996126 fliF 14293754 fliF Brachyspira pilosicoli P43/6/78 flagellar MS-ring protein YP_007234476.1 994429 R 1042417 CDS YP_007234477.1 431807579 14293755 complement(996343..996828) 1 NC_019908.1 COG1546 Uncharacterized protein (competence- and mitomycin-induced); competence damaged protein CinA 996828 14293755 BPP43_04750 Brachyspira pilosicoli P43/6/78 competence damaged protein CinA YP_007234477.1 996343 R 1042417 CDS YP_007234478.1 431807580 14293756 complement(996840..997037) 1 NC_019908.1 COG1687 Predicted branched-chain amino acid permeases (azaleucine resistance); branched-chain amino acid permease AzlD 997037 14293756 BPP43_04755 Brachyspira pilosicoli P43/6/78 branched-chain amino acid permease AzlD YP_007234478.1 996840 R 1042417 CDS YP_007234479.1 431807581 14293757 complement(997164..997880) 1 NC_019908.1 COG1296 Predicted branched-chain amino acid permease (azaleucine resistance); AzlC-like protein 997880 14293757 BPP43_04760 Brachyspira pilosicoli P43/6/78 AzlC-like protein YP_007234479.1 997164 R 1042417 CDS YP_007234480.1 431807582 14293758 complement(997956..998693) 1 NC_019908.1 COG3142 Uncharacterized protein involved in copper resistance; copper transporter-like protein CutC 998693 14293758 BPP43_04765 Brachyspira pilosicoli P43/6/78 copper transporter-like protein CutC YP_007234480.1 997956 R 1042417 CDS YP_007234481.1 431807583 14293759 complement(998980..1000083) 1 NC_019908.1 variable surface protein VspE 1000083 14293759 BPP43_04770 Brachyspira pilosicoli P43/6/78 variable surface protein VspE YP_007234481.1 998980 R 1042417 CDS YP_007234482.1 431807584 14293760 complement(1000362..1000715) 1 NC_019908.1 COG0386 Glutathione peroxidase; glutathione peroxidase 1000715 14293760 BPP43_04775 Brachyspira pilosicoli P43/6/78 glutathione peroxidase YP_007234482.1 1000362 R 1042417 CDS YP_007234483.1 431807585 14293761 complement(1000740..1000844) 1 NC_019908.1 COG0386 Glutathione peroxidase; glutathione peroxidase 1000844 14293761 BPP43_04780 Brachyspira pilosicoli P43/6/78 glutathione peroxidase YP_007234483.1 1000740 R 1042417 CDS YP_007234484.1 431807586 14293762 complement(1000920..1001417) 1 NC_019908.1 COG2077 Peroxiredoxin; thiol peroxidase 1001417 14293762 BPP43_04785 Brachyspira pilosicoli P43/6/78 thiol peroxidase YP_007234484.1 1000920 R 1042417 CDS YP_007234485.1 431807587 14293763 complement(1002900..1003049) 1 NC_019908.1 UDP-N-acetylmuramyl tripeptide synthetase 1003049 14293763 BPP43_04800 Brachyspira pilosicoli P43/6/78 UDP-N-acetylmuramyl tripeptide synthetase YP_007234485.1 1002900 R 1042417 CDS YP_007234486.1 431807588 14293764 complement(1003115..1003372) 1 NC_019908.1 septum formation initiator 1003372 14293764 BPP43_04805 Brachyspira pilosicoli P43/6/78 septum formation initiator YP_007234486.1 1003115 R 1042417 CDS YP_007234487.1 431807589 14293765 complement(1003463..1004356) 1 NC_019908.1 COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; S-adenosyl-methyltransferase MraW 1004356 14293765 BPP43_04810 Brachyspira pilosicoli P43/6/78 S-adenosyl-methyltransferase MraW YP_007234487.1 1003463 R 1042417 CDS YP_007234488.1 431807590 14293766 1004530..1004796 1 NC_019908.1 hypothetical protein 1004796 14293766 BPP43_04815 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234488.1 1004530 D 1042417 CDS YP_007234489.1 431807591 14293767 1004830..1006869 1 NC_019908.1 COG0556 Helicase subunit of the DNA excision repair complex; excinuclease ABC subunit B 1006869 14293767 BPP43_04820 Brachyspira pilosicoli P43/6/78 excinuclease ABC subunit B YP_007234489.1 1004830 D 1042417 CDS YP_007234490.1 431807592 14293768 complement(1006873..1008204) 1 NC_019908.1 COG0534 Na+-driven multidrug efflux pump; Na+-driven multidrug efflux pump 1008204 14293768 BPP43_04825 Brachyspira pilosicoli P43/6/78 Na+-driven multidrug efflux pump YP_007234490.1 1006873 R 1042417 CDS YP_007234491.1 431807593 14293769 1008243..1008347 1 NC_019908.1 hypothetical protein 1008347 14293769 BPP43_04830 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234491.1 1008243 D 1042417 CDS YP_007234492.1 431807594 14293770 1008344..1008934 1 NC_019908.1 COG2755 Lysophospholipase L1 and related esterases; arylesterase 1008934 14293770 BPP43_04835 Brachyspira pilosicoli P43/6/78 arylesterase YP_007234492.1 1008344 D 1042417 CDS YP_007234493.1 431807595 14293771 complement(1009063..1010541) 1 NC_019908.1 hypothetical protein 1010541 14293771 BPP43_04840 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234493.1 1009063 R 1042417 CDS YP_007234494.1 431807596 14293772 complement(1010644..1011378) 1 NC_019908.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase 1011378 14293772 BPP43_04845 Brachyspira pilosicoli P43/6/78 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_007234494.1 1010644 R 1042417 CDS YP_007234495.1 431807597 14293773 complement(1011462..1012403) 1 NC_019908.1 hypothetical protein 1012403 14293773 BPP43_04850 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234495.1 1011462 R 1042417 CDS YP_007234496.1 431807598 14293774 complement(1012419..1013381) 1 NC_019908.1 hypothetical protein 1013381 14293774 BPP43_04855 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234496.1 1012419 R 1042417 CDS YP_007234497.1 431807599 14293775 complement(1013400..1014371) 1 NC_019908.1 hypothetical protein 1014371 14293775 BPP43_04860 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234497.1 1013400 R 1042417 CDS YP_007234498.1 431807600 14293776 complement(1014390..1015271) 1 NC_019908.1 hypothetical protein 1015271 14293776 BPP43_04865 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234498.1 1014390 R 1042417 CDS YP_007234499.1 431807601 14293777 complement(1015302..1016333) 1 NC_019908.1 hypothetical protein 1016333 14293777 BPP43_04870 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234499.1 1015302 R 1042417 CDS YP_007234500.1 431807602 14293778 complement(1016441..1017871) 1 NC_019908.1 hypothetical protein 1017871 14293778 BPP43_04875 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234500.1 1016441 R 1042417 CDS YP_007234501.1 431807603 14293779 complement(1017940..1018695) 1 NC_019908.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 1018695 14293779 BPP43_04880 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234501.1 1017940 R 1042417 CDS YP_007234502.1 431807604 14293780 1020434..1022248 1 NC_019908.1 COG0358 DNA primase (bacterial type); DNA primase 1022248 14293780 BPP43_04895 Brachyspira pilosicoli P43/6/78 DNA primase YP_007234502.1 1020434 D 1042417 CDS YP_007234503.1 431807605 14293781 complement(1024056..1025927) 1 NC_019908.1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming); AMP-dependent synthetase and ligase 1025927 14293781 BPP43_04910 Brachyspira pilosicoli P43/6/78 AMP-dependent synthetase and ligase YP_007234503.1 1024056 R 1042417 CDS YP_007234504.1 431807606 14293782 1027495..1027758 1 NC_019908.1 COG0526 Thiol-disulfide isomerase and thioredoxins; hypothetical protein 1027758 14293782 BPP43_04925 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234504.1 1027495 D 1042417 CDS YP_007234505.1 431807607 14293783 1027776..1028882 1 NC_019908.1 COG0701 Predicted permeases; permease 1028882 14293783 BPP43_04930 Brachyspira pilosicoli P43/6/78 permease YP_007234505.1 1027776 D 1042417 CDS YP_007234506.1 431807608 14293784 1028876..1029331 1 NC_019908.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; lipoprotein 1029331 14293784 BPP43_04935 Brachyspira pilosicoli P43/6/78 lipoprotein YP_007234506.1 1028876 D 1042417 CDS YP_007234507.1 431807609 14293785 1029362..1030534 1 NC_019908.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; periplasmic-binding protein-like II family lipoprotein 1030534 14293785 BPP43_04940 Brachyspira pilosicoli P43/6/78 periplasmic-binding protein-like II family lipoprotein YP_007234507.1 1029362 D 1042417 CDS YP_007234508.1 431807610 14293786 1030557..1031384 1 NC_019908.1 hypothetical protein 1031384 14293786 BPP43_04945 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234508.1 1030557 D 1042417 CDS YP_007234509.1 431807611 14293787 1031336..1032163 1 NC_019908.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; nitrate/sulfonate/bicarbonate ABC transporter permease 1032163 14293787 BPP43_04950 Brachyspira pilosicoli P43/6/78 nitrate/sulfonate/bicarbonate ABC transporter permease YP_007234509.1 1031336 D 1042417 CDS YP_007234510.1 431807612 14293788 1032965..1033450 1 NC_019908.1 hypothetical protein 1033450 14293788 BPP43_04965 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234510.1 1032965 D 1042417 CDS YP_007234511.1 431807613 14293789 1033457..1033585 1 NC_019908.1 hypothetical protein 1033585 14293789 BPP43_04970 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234511.1 1033457 D 1042417 CDS YP_007234512.1 431807614 14293790 complement(1033675..1035435) 1 NC_019908.1 COG0322 Nuclease subunit of the excinuclease complex; excinuclease ABC subunit C 1035435 14293790 BPP43_04975 Brachyspira pilosicoli P43/6/78 excinuclease ABC subunit C YP_007234512.1 1033675 R 1042417 CDS YP_007234513.1 431807615 14293791 1036146..1037189 1 NC_019908.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; alcohol dehydrogenase 1037189 14293791 BPP43_04980 Brachyspira pilosicoli P43/6/78 alcohol dehydrogenase YP_007234513.1 1036146 D 1042417 CDS YP_007234514.1 431807616 14293792 1037299..1039212 1 NC_019908.1 COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; DNA gyrase subunit B 1039212 14293792 BPP43_04985 Brachyspira pilosicoli P43/6/78 DNA gyrase subunit B YP_007234514.1 1037299 D 1042417 CDS YP_007234515.1 431807617 14293793 1039233..1040195 1 NC_019908.1 COG0492 Thioredoxin reductase; thioredoxin reductase 1040195 14293793 BPP43_04990 Brachyspira pilosicoli P43/6/78 thioredoxin reductase YP_007234515.1 1039233 D 1042417 CDS YP_007234516.1 431807618 14293794 1040222..1040524 1 NC_019908.1 COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system galactitol-specific transporter subunit IIB 1040524 14293794 BPP43_04995 Brachyspira pilosicoli P43/6/78 PTS system galactitol-specific transporter subunit IIB YP_007234516.1 1040222 D 1042417 CDS YP_007234517.1 431807619 14293795 complement(1042517..1043449) 1 NC_019908.1 COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 1043449 14293795 BPP43_05010 Brachyspira pilosicoli P43/6/78 N-acetylmuramoyl-L-alanine amidase YP_007234517.1 1042517 R 1042417 CDS YP_007234518.1 431807620 14293796 complement(1043401..1045506) 1 NC_019908.1 COG0550 Topoisomerase IA; DNA topoisomerase I 1045506 14293796 BPP43_05015 Brachyspira pilosicoli P43/6/78 DNA topoisomerase I YP_007234518.1 1043401 R 1042417 CDS YP_007234519.1 431807621 14293797 complement(1045525..1045620) 1 NC_019908.1 DNA protecting protein DprA 1045620 14293797 BPP43_05020 Brachyspira pilosicoli P43/6/78 DNA protecting protein DprA YP_007234519.1 1045525 R 1042417 CDS YP_007234520.1 431807622 14293798 complement(1045622..1046764) 1 NC_019908.1 COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; DNA protecting protein DprA 1046764 14293798 BPP43_05025 Brachyspira pilosicoli P43/6/78 DNA protecting protein DprA YP_007234520.1 1045622 R 1042417 CDS YP_007234521.1 431807623 14293799 complement(1046792..1047502) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1047502 14293799 BPP43_05030 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234521.1 1046792 R 1042417 CDS YP_007234522.1 431807624 14293800 1047869..1049260 1 NC_019908.1 sialidase (neuraminidase) family protein-like protein 1049260 14293800 BPP43_05035 Brachyspira pilosicoli P43/6/78 sialidase (neuraminidase) family protein-like protein YP_007234522.1 1047869 D 1042417 CDS YP_007234523.1 431807625 14293801 1049350..1050723 1 NC_019908.1 COG4409 Neuraminidase (sialidase); sialidase (neuraminidase) family protein-like protein 1050723 14293801 BPP43_05040 Brachyspira pilosicoli P43/6/78 sialidase (neuraminidase) family protein-like protein YP_007234523.1 1049350 D 1042417 CDS YP_007234524.1 431807626 14293802 1050907..1052451 1 NC_019908.1 sialidase (neuraminidase) family protein-like protein 1052451 14293802 BPP43_05045 Brachyspira pilosicoli P43/6/78 sialidase (neuraminidase) family protein-like protein YP_007234524.1 1050907 D 1042417 CDS YP_007234525.1 431807627 14293803 1052606..1054399 1 NC_019908.1 COG1274 Phosphoenolpyruvate carboxykinase (GTP); phosphoenolpyruvate carboxykinase 1054399 14293803 BPP43_05050 Brachyspira pilosicoli P43/6/78 phosphoenolpyruvate carboxykinase YP_007234525.1 1052606 D 1042417 CDS YP_007234526.1 431807628 14293804 complement(1054538..1056145) 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 1056145 14293804 BPP43_05055 Brachyspira pilosicoli P43/6/78 family 5 extracellular solute-binding protein YP_007234526.1 1054538 R 1042417 CDS YP_007234527.1 431807629 14293805 1056415..1056666 1 NC_019908.1 COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; hypothetical protein 1056666 14293805 BPP43_05060 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234527.1 1056415 D 1042417 CDS YP_007234528.1 431807630 14293806 1056697..1058121 1 NC_019908.1 COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; thiamine biosynthesis protein ThiH 1058121 thiH 14293806 thiH Brachyspira pilosicoli P43/6/78 thiamine biosynthesis protein ThiH YP_007234528.1 1056697 D 1042417 CDS YP_007234529.1 431807631 14293807 1058529..1059707 1 NC_019908.1 COG1160 Predicted GTPases; GTP-binding protein 1059707 14293807 BPP43_05070 Brachyspira pilosicoli P43/6/78 GTP-binding protein YP_007234529.1 1058529 D 1042417 CDS YP_007234530.1 431807632 14293808 1059731..1060852 1 NC_019908.1 COG0502 Biotin synthase and related enzymes; biotin synthase 1060852 14293808 BPP43_05075 Brachyspira pilosicoli P43/6/78 biotin synthase YP_007234530.1 1059731 D 1042417 CDS YP_007234531.1 431807633 14293809 complement(1060902..1061243) 1 NC_019908.1 COG3323 Uncharacterized protein conserved in bacteria; nitrogen regulatory protein PII 1061243 14293809 BPP43_05080 Brachyspira pilosicoli P43/6/78 nitrogen regulatory protein PII YP_007234531.1 1060902 R 1042417 CDS YP_007234532.1 431807634 14293810 complement(1061266..1061748) 1 NC_019908.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 1061748 14293810 BPP43_05085 Brachyspira pilosicoli P43/6/78 N-acetyltransferase GCN5 YP_007234532.1 1061266 R 1042417 CDS YP_007234533.1 431807635 14293811 1061875..1063215 1 NC_019908.1 COG0534 Na+-driven multidrug efflux pump; Na+-driven multidrug efflux pump 1063215 14293811 BPP43_05090 Brachyspira pilosicoli P43/6/78 Na+-driven multidrug efflux pump YP_007234533.1 1061875 D 1042417 CDS YP_007234534.1 431807636 14293812 complement(1063573..1064088) 1 NC_019908.1 COG0693 Putative intracellular protease/amidase; Pfpi family intracellular protease 1064088 14293812 BPP43_05095 Brachyspira pilosicoli P43/6/78 Pfpi family intracellular protease YP_007234534.1 1063573 R 1042417 CDS YP_007234535.1 431807637 14293813 complement(1064109..1065602) 1 NC_019908.1 COG0297 Glycogen synthase; glycogen/starch synthase 1065602 14293813 BPP43_05100 Brachyspira pilosicoli P43/6/78 glycogen/starch synthase YP_007234535.1 1064109 R 1042417 CDS YP_007234536.1 431807638 14293814 complement(1065916..1066059) 1 NC_019908.1 hypothetical protein 1066059 14293814 BPP43_05105 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234536.1 1065916 R 1042417 CDS YP_007234537.1 431807639 14293815 complement(1066029..1066343) 1 NC_019908.1 hypothetical protein 1066343 14293815 BPP43_05110 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234537.1 1066029 R 1042417 CDS YP_007234538.1 431807640 14293816 complement(1066350..1068272) 1 NC_019908.1 hypothetical protein 1068272 14293816 BPP43_05115 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234538.1 1066350 R 1042417 CDS YP_007234539.1 431807641 14293817 complement(1068395..1070050) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 1070050 14293817 BPP43_05120 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234539.1 1068395 R 1042417 CDS YP_007234540.1 431807642 14293818 1072513..1074069 1 NC_019908.1 COG2978 Putative p-aminobenzoyl-glutamate transporter; ABC transporter family protein 1074069 14293818 BPP43_05135 Brachyspira pilosicoli P43/6/78 ABC transporter family protein YP_007234540.1 1072513 D 1042417 CDS YP_007234541.1 431807643 14293819 1074098..1075336 1 NC_019908.1 COG2195 Di- and tripeptidases; peptidase T 1075336 14293819 BPP43_05140 Brachyspira pilosicoli P43/6/78 peptidase T YP_007234541.1 1074098 D 1042417 CDS YP_007234542.1 431807644 14293820 complement(1075401..1076492) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 1076492 14293820 BPP43_05145 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234542.1 1075401 R 1042417 CDS YP_007234543.1 431807645 14293821 1078154..1080598 1 NC_019908.1 COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; 1-aminocyclopropane-1-carboxylate deaminase 1080598 14293821 BPP43_05160 Brachyspira pilosicoli P43/6/78 1-aminocyclopropane-1-carboxylate deaminase YP_007234543.1 1078154 D 1042417 CDS YP_007234544.1 431807646 14293822 1080665..1081333 1 NC_019908.1 hypothetical protein 1081333 14293822 BPP43_05165 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234544.1 1080665 D 1042417 CDS YP_007234545.1 431807647 14293823 1081431..1081997 1 NC_019908.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 1081997 14293823 BPP43_05170 Brachyspira pilosicoli P43/6/78 TetR family transcriptional regulator YP_007234545.1 1081431 D 1042417 CDS YP_007234546.1 431807648 14293824 1082004..1083551 1 NC_019908.1 hypothetical protein 1083551 14293824 BPP43_05175 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234546.1 1082004 D 1042417 CDS YP_007234547.1 431807649 14293825 complement(1083611..1083967) 1 NC_019908.1 FMN-binding domain-containing protein 1083967 14293825 BPP43_05180 Brachyspira pilosicoli P43/6/78 FMN-binding domain-containing protein YP_007234547.1 1083611 R 1042417 CDS YP_007234548.1 431807650 14293826 complement(1084051..1084446) 1 NC_019908.1 hypothetical protein 1084446 14293826 BPP43_05185 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234548.1 1084051 R 1042417 CDS YP_007234549.1 431807651 14293827 1084589..1086151 1 NC_019908.1 COG2319 FOG: WD40 repeat; hypothetical protein 1086151 14293827 BPP43_05190 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234549.1 1084589 D 1042417 CDS YP_007234550.1 431807652 14293828 complement(1086422..1087414) 1 NC_019908.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; ribosomal large subunit pseudouridine synthase C 1087414 14293828 BPP43_05195 Brachyspira pilosicoli P43/6/78 ribosomal large subunit pseudouridine synthase C YP_007234550.1 1086422 R 1042417 CDS YP_007234551.1 431807653 14293829 complement(1087434..1087952) 1 NC_019908.1 COG0717 Deoxycytidine deaminase; deoxycytidine triphosphate deaminase 1087952 dcd 14293829 dcd Brachyspira pilosicoli P43/6/78 deoxycytidine triphosphate deaminase YP_007234551.1 1087434 R 1042417 CDS YP_007234552.1 431807654 14293830 1088052..1089383 1 NC_019908.1 COG0166 Glucose-6-phosphate isomerase; glucose-6-phosphate isomerase 1089383 14293830 BPP43_05205 Brachyspira pilosicoli P43/6/78 glucose-6-phosphate isomerase YP_007234552.1 1088052 D 1042417 CDS YP_007234553.1 431807655 14293831 1089518..1090312 1 NC_019908.1 COG4786 Flagellar basal body rod protein; flagellar basal body rod protein FlgG 1090312 flgG 14293831 flgG Brachyspira pilosicoli P43/6/78 flagellar basal body rod protein FlgG YP_007234553.1 1089518 D 1042417 CDS YP_007234554.1 431807656 14293832 complement(1090353..1090910) 1 NC_019908.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); lytic murein transglycosylase lmt23D 1090910 14293832 BPP43_05215 Brachyspira pilosicoli P43/6/78 lytic murein transglycosylase lmt23D YP_007234554.1 1090353 R 1042417 CDS YP_007234555.1 431807657 14293833 1091131..1093374 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1093374 14293833 BPP43_05220 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234555.1 1091131 D 1042417 CDS YP_007234556.1 431807658 14293834 complement(1093380..1095968) 1 NC_019908.1 COG0747 ABC-type dipeptide transport system, periplasmic component; solute-binding protein like protein 1095968 14293834 BPP43_05225 Brachyspira pilosicoli P43/6/78 solute-binding protein like protein YP_007234556.1 1093380 R 1042417 CDS YP_007234557.1 431807659 14293835 complement(1096080..1096481) 1 NC_019908.1 hypothetical protein 1096481 14293835 BPP43_05230 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234557.1 1096080 R 1042417 CDS YP_007234558.1 431807660 14293836 complement(1096611..1097117) 1 NC_019908.1 hypothetical protein 1097117 14293836 BPP43_05235 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234558.1 1096611 R 1042417 CDS YP_007234559.1 431807661 14293837 1097263..1098882 1 NC_019908.1 COG0504 CTP synthase (UTP-ammonia lyase); CTP synthetase 1098882 pyrG 14293837 pyrG Brachyspira pilosicoli P43/6/78 CTP synthetase YP_007234559.1 1097263 D 1042417 CDS YP_007234560.1 431807662 14293838 complement(1099035..1099871) 1 NC_019908.1 COG0287 Prephenate dehydrogenase; prephenate dehydrogenase 1099871 14293838 BPP43_05245 Brachyspira pilosicoli P43/6/78 prephenate dehydrogenase YP_007234560.1 1099035 R 1042417 CDS YP_007234561.1 431807663 14293839 complement(1100055..1100711) 1 NC_019908.1 COG1432 Uncharacterized conserved protein; hypothetical protein 1100711 14293839 BPP43_05250 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234561.1 1100055 R 1042417 CDS YP_007234562.1 431807664 14293840 1101911..1102579 1 NC_019908.1 COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; flavin reductase-like FMN-binding protein 1102579 14293840 BPP43_05265 Brachyspira pilosicoli P43/6/78 flavin reductase-like FMN-binding protein YP_007234562.1 1101911 D 1042417 CDS YP_007234563.1 431807665 14293841 1102662..1103516 1 NC_019908.1 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; periplasmic solute-binding protein 1103516 14293841 BPP43_05270 Brachyspira pilosicoli P43/6/78 periplasmic solute-binding protein YP_007234563.1 1102662 D 1042417 CDS YP_007234564.1 431807666 14293842 1103534..1104271 1 NC_019908.1 COG1121 ABC-type Mn/Zn transport systems, ATPase component; ABC transporter-like protein 1104271 14293842 BPP43_05275 Brachyspira pilosicoli P43/6/78 ABC transporter-like protein YP_007234564.1 1103534 D 1042417 CDS YP_007234565.1 431807667 14293843 1104295..1105098 1 NC_019908.1 COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; ABC 3 transport family protein 1105098 14293843 BPP43_05280 Brachyspira pilosicoli P43/6/78 ABC 3 transport family protein YP_007234565.1 1104295 D 1042417 CDS YP_007234566.1 431807668 14293844 complement(1105230..1107041) 1 NC_019908.1 COG0481 Membrane GTPase LepA; GTP-binding protein LepA 1107041 14293844 BPP43_05285 Brachyspira pilosicoli P43/6/78 GTP-binding protein LepA YP_007234566.1 1105230 R 1042417 CDS YP_007234567.1 431807669 14293845 complement(1107157..1107618) 1 NC_019908.1 hypothetical protein 1107618 14293845 BPP43_05290 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234567.1 1107157 R 1042417 CDS YP_007234568.1 431807670 14293846 1107888..1108592 1 NC_019908.1 COG3382 Uncharacterized conserved protein; hypothetical protein 1108592 14293846 BPP43_05295 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234568.1 1107888 D 1042417 CDS YP_007234569.1 431807671 14293847 complement(1111442..1112077) 1 NC_019908.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 1112077 14293847 BPP43_05310 Brachyspira pilosicoli P43/6/78 type 11 methyltransferase YP_007234569.1 1111442 R 1042417 CDS YP_007234570.1 431807672 14293848 complement(1112114..1113112) 1 NC_019908.1 COG2017 Galactose mutarotase and related enzymes; aldose-1-epimerase 1113112 14293848 BPP43_05315 Brachyspira pilosicoli P43/6/78 aldose-1-epimerase YP_007234570.1 1112114 R 1042417 CDS YP_007234571.1 431807673 14293849 1113267..1115354 1 NC_019908.1 COG0751 Glycyl-tRNA synthetase, beta subunit; glycyl tRNA synthetase subunit beta 1115354 14293849 BPP43_05320 Brachyspira pilosicoli P43/6/78 glycyl tRNA synthetase subunit beta YP_007234571.1 1113267 D 1042417 CDS YP_007234572.1 431807674 14293850 complement(1115461..1116120) 1 NC_019908.1 COG2364 Predicted membrane protein; hypothetical protein 1116120 14293850 BPP43_05325 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234572.1 1115461 R 1042417 CDS YP_007234573.1 431807675 14293851 complement(1116123..1116515) 1 NC_019908.1 COG1846 Transcriptional regulators; transcriptional regulator MarR 1116515 14293851 BPP43_05330 Brachyspira pilosicoli P43/6/78 transcriptional regulator MarR YP_007234573.1 1116123 R 1042417 CDS YP_007234574.1 431807676 14293852 1116815..1117249 1 NC_019908.1 hypothetical protein 1117249 14293852 BPP43_05335 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234574.1 1116815 D 1042417 CDS YP_007234575.1 431807677 14293853 1117385..1118113 1 NC_019908.1 hypothetical protein 1118113 14293853 BPP43_05340 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234575.1 1117385 D 1042417 CDS YP_007234576.1 431807678 14293854 1118552..1119424 1 NC_019908.1 COG0061 Predicted sugar kinase; inorganic polyphosphate ATP-dependent NAD kinase 1119424 14293854 BPP43_05345 Brachyspira pilosicoli P43/6/78 inorganic polyphosphate ATP-dependent NAD kinase YP_007234576.1 1118552 D 1042417 CDS YP_007234577.1 431807679 14293855 1119427..1121154 1 NC_019908.1 COG0497 ATPase involved in DNA repair; repair and genetic recombination protein 1121154 14293855 BPP43_05350 Brachyspira pilosicoli P43/6/78 repair and genetic recombination protein YP_007234577.1 1119427 D 1042417 CDS YP_007234578.1 431807680 14293856 complement(1121553..1122062) 1 NC_019908.1 COG0778 Nitroreductase; nitroreductase 1122062 14293856 BPP43_05355 Brachyspira pilosicoli P43/6/78 nitroreductase YP_007234578.1 1121553 R 1042417 CDS YP_007234579.1 431807681 14293857 complement(1122101..1123081) 1 NC_019908.1 COG1270 Cobalamin biosynthesis protein CobD/CbiB; cobalamin biosynthesis protein CobD 1123081 14293857 BPP43_05360 Brachyspira pilosicoli P43/6/78 cobalamin biosynthesis protein CobD YP_007234579.1 1122101 R 1042417 CDS YP_007234580.1 431807682 14293858 complement(1123101..1123691) 1 NC_019908.1 COG0406 Fructose-2,6-bisphosphatase; fructose-2,6-bisphosphatase 1123691 14293858 BPP43_05365 Brachyspira pilosicoli P43/6/78 fructose-2,6-bisphosphatase YP_007234580.1 1123101 R 1042417 CDS YP_007234581.1 431807683 14293859 complement(1123710..1124600) 1 NC_019908.1 COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; phospholipase 1124600 14293859 BPP43_05370 Brachyspira pilosicoli P43/6/78 phospholipase YP_007234581.1 1123710 R 1042417 CDS YP_007234582.1 431807684 14293860 complement(1124629..1126113) 1 NC_019908.1 hypothetical protein 1126113 14293860 BPP43_05375 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234582.1 1124629 R 1042417 CDS YP_007234583.1 431807685 14293861 1126291..1126944 1 NC_019908.1 COG0266 Formamidopyrimidine-DNA glycosylase; formamidopyrimidine DNA-glycosylase 1126944 14293861 BPP43_05380 Brachyspira pilosicoli P43/6/78 formamidopyrimidine DNA-glycosylase YP_007234583.1 1126291 D 1042417 CDS YP_007234584.1 431807686 14293862 1127048..1127464 1 NC_019908.1 COG0629 Single-stranded DNA-binding protein; single-strand binding protein 1127464 14293862 BPP43_05385 Brachyspira pilosicoli P43/6/78 single-strand binding protein YP_007234584.1 1127048 D 1042417 CDS YP_007234585.1 431807687 14293863 complement(1127433..1128044) 1 NC_019908.1 COG0125 Thymidylate kinase; thymidylate kinase 1128044 14293863 BPP43_05390 Brachyspira pilosicoli P43/6/78 thymidylate kinase YP_007234585.1 1127433 R 1042417 CDS YP_007234586.1 431807688 14293864 complement(1128090..1129238) 1 NC_019908.1 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; phospho N-acetylmuramoyl pentapeptide transferase 1129238 14293864 BPP43_05395 Brachyspira pilosicoli P43/6/78 phospho N-acetylmuramoyl pentapeptide transferase YP_007234586.1 1128090 R 1042417 CDS YP_007234587.1 431807689 14293865 complement(1129382..1130182) 1 NC_019908.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); NADP-dependent 7-alpha-hydroxysteroid dehydrogenase 1130182 14293865 BPP43_05400 Brachyspira pilosicoli P43/6/78 NADP-dependent 7-alpha-hydroxysteroid dehydrogenase YP_007234587.1 1129382 R 1042417 CDS YP_007234588.1 431807690 14293866 1130351..1131478 1 NC_019908.1 COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); DNA polymerase III subunit beta 1131478 14293866 BPP43_05405 Brachyspira pilosicoli P43/6/78 DNA polymerase III subunit beta YP_007234588.1 1130351 D 1042417 CDS YP_007234589.1 431807691 14293867 1132087..1132875 1 NC_019908.1 hypothetical protein 1132875 14293867 BPP43_05410 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234589.1 1132087 D 1042417 CDS YP_007234590.1 431807692 14293868 1132896..1134380 1 NC_019908.1 hypothetical protein 1134380 14293868 BPP43_05415 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234590.1 1132896 D 1042417 CDS YP_007234591.1 431807693 14293869 1134527..1135369 1 NC_019908.1 hypothetical protein 1135369 14293869 BPP43_05420 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234591.1 1134527 D 1042417 CDS YP_007234592.1 431807694 14293870 complement(1135374..1136426) 1 NC_019908.1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; pyridoxal phosphate-dependent aminotransferase 1136426 14293870 BPP43_05425 Brachyspira pilosicoli P43/6/78 pyridoxal phosphate-dependent aminotransferase YP_007234592.1 1135374 R 1042417 CDS YP_007234593.1 431807695 14293871 1136601..1137065 1 NC_019908.1 COG0782 Transcription elongation factor; GreA/GreB family elongation factor 1137065 14293871 BPP43_05430 Brachyspira pilosicoli P43/6/78 GreA/GreB family elongation factor YP_007234593.1 1136601 D 1042417 CDS YP_007234594.1 431807696 14293872 complement(1137210..1137857) 1 NC_019908.1 COG0344 Predicted membrane protein; hypothetical protein 1137857 14293872 BPP43_05435 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234594.1 1137210 R 1042417 CDS YP_007234595.1 431807697 14293873 complement(1137847..1139316) 1 NC_019908.1 COG1160 Predicted GTPases; GTP-binding protein EngA 1139316 14293873 BPP43_05440 Brachyspira pilosicoli P43/6/78 GTP-binding protein EngA YP_007234595.1 1137847 R 1042417 CDS YP_007234596.1 431807698 14293874 complement(1139440..1139874) 1 NC_019908.1 hypothetical protein 1139874 14293874 BPP43_05445 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234596.1 1139440 R 1042417 CDS YP_007234597.1 431807699 14294837 1140098..1140292 1 NC_019908.1 COG0333 Ribosomal protein L32; 50S ribosomal protein L32 1140292 14294837 BPP43_05450 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L32 YP_007234597.1 1140098 D 1042417 CDS YP_007234598.1 431807700 14294838 1141347..1142201 1 NC_019908.1 COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; 3-oxoacyl-ACP synthase 1142201 14294838 BPP43_05465 Brachyspira pilosicoli P43/6/78 3-oxoacyl-ACP synthase YP_007234598.1 1141347 D 1042417 CDS YP_007234599.1 431807701 14294839 1142254..1143561 1 NC_019908.1 COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC; RnfABCDGE type electron transport complex subunit C 1143561 14294839 BPP43_05470 Brachyspira pilosicoli P43/6/78 RnfABCDGE type electron transport complex subunit C YP_007234599.1 1142254 D 1042417 CDS YP_007234600.1 431807702 14294840 1143566..1144657 1 NC_019908.1 COG4658 Predicted NADH:ubiquinone oxidoreductase, subunit RnfD; RnfABCDGE type electron transport complex subunit D 1144657 14294840 BPP43_05475 Brachyspira pilosicoli P43/6/78 RnfABCDGE type electron transport complex subunit D YP_007234600.1 1143566 D 1042417 CDS YP_007234601.1 431807703 14294841 1144654..1145226 1 NC_019908.1 COG4659 Predicted NADH:ubiquinone oxidoreductase, subunit RnfG; RnfABCDGE type electron transport complex subunit G 1145226 14294841 BPP43_05480 Brachyspira pilosicoli P43/6/78 RnfABCDGE type electron transport complex subunit G YP_007234601.1 1144654 D 1042417 CDS YP_007234602.1 431807704 14294842 1145624..1146211 1 NC_019908.1 hypothetical protein 1146211 14294842 BPP43_05485 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234602.1 1145624 D 1042417 CDS YP_007234603.1 431807705 14294843 complement(1146205..1148613) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 1148613 14294843 BPP43_05490 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234603.1 1146205 R 1042417 CDS YP_007234604.1 431807706 14294844 complement(1148701..1150056) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 1150056 14294844 BPP43_05495 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234604.1 1148701 R 1042417 CDS YP_007234605.1 431807707 14294845 complement(1150072..1152975) 1 NC_019908.1 COG1452 Organic solvent tolerance protein OstA; hypothetical protein 1152975 14294845 BPP43_05500 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234605.1 1150072 R 1042417 CDS YP_007234606.1 431807708 14294846 complement(1153017..1154213) 1 NC_019908.1 COG0162 Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 1154213 14294846 BPP43_05505 Brachyspira pilosicoli P43/6/78 tyrosyl-tRNA synthetase YP_007234606.1 1153017 R 1042417 CDS YP_007234607.1 431807709 14294847 1154348..1154680 1 NC_019908.1 COG0607 Rhodanese-related sulfurtransferase; rhodanese-like domain-containing protein 1154680 14294847 BPP43_05510 Brachyspira pilosicoli P43/6/78 rhodanese-like domain-containing protein YP_007234607.1 1154348 D 1042417 CDS YP_007234608.1 431807710 14294848 1154768..1154869 1 NC_019908.1 COG0254 Ribosomal protein L31; 50S ribosomal protein L31 1154869 14294848 BPP43_05515 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L31 YP_007234608.1 1154768 D 1042417 CDS YP_007234609.1 431807711 14294849 1155069..1155224 1 NC_019908.1 hypothetical protein 1155224 14294849 BPP43_05520 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234609.1 1155069 D 1042417 CDS YP_007234610.1 431807712 14294850 complement(1155683..1157482) 1 NC_019908.1 COG0323 DNA mismatch repair enzyme (predicted ATPase); DNA mismatch repair protein 1157482 14294850 BPP43_05525 Brachyspira pilosicoli P43/6/78 DNA mismatch repair protein YP_007234610.1 1155683 R 1042417 CDS YP_007234611.1 431807713 14294851 1157613..1157831 1 NC_019908.1 hypothetical protein 1157831 14294851 BPP43_05530 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234611.1 1157613 D 1042417 CDS YP_007234612.1 431807714 14294852 1157929..1158078 1 NC_019908.1 hypothetical protein 1158078 14294852 BPP43_05535 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234612.1 1157929 D 1042417 CDS YP_007234613.1 431807715 14294853 complement(1161757..1162554) 1 NC_019908.1 COG1968 Uncharacterized bacitracin resistance protein; undecaprenyl pyrophosphate phosphatase 1162554 14294853 BPP43_05550 Brachyspira pilosicoli P43/6/78 undecaprenyl pyrophosphate phosphatase YP_007234613.1 1161757 R 1042417 CDS YP_007234614.1 431807716 14294854 1162809..1163174 1 NC_019908.1 COG1396 Predicted transcriptional regulators; merR family transcriptional regulator 1163174 14294854 BPP43_05555 Brachyspira pilosicoli P43/6/78 merR family transcriptional regulator YP_007234614.1 1162809 D 1042417 CDS YP_007234615.1 431807717 14294855 complement(1163223..1164263) 1 NC_019908.1 COG0457 FOG: TPR repeat; hemolysin 1164263 14294855 BPP43_05560 Brachyspira pilosicoli P43/6/78 hemolysin YP_007234615.1 1163223 R 1042417 CDS YP_007234616.1 431807718 14294856 complement(1164278..1165555) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1165555 14294856 BPP43_05565 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234616.1 1164278 R 1042417 CDS YP_007234617.1 431807719 14294857 complement(1165641..1166498) 1 NC_019908.1 COG2035 Predicted membrane protein; integral membrane protein 1166498 14294857 BPP43_05570 Brachyspira pilosicoli P43/6/78 integral membrane protein YP_007234617.1 1165641 R 1042417 CDS YP_007234618.1 431807720 14294858 complement(1166598..1166981) 1 NC_019908.1 COG0251 Putative translation initiation inhibitor, yjgF family; endoribonuclease 1166981 14294858 BPP43_05575 Brachyspira pilosicoli P43/6/78 endoribonuclease YP_007234618.1 1166598 R 1042417 CDS YP_007234619.1 431807721 14294860 1167301..1168254 1 NC_019908.1 COG0462 Phosphoribosylpyrophosphate synthetase; ribose-phosphate pyrophosphokinase 1168254 14294860 BPP43_05580 Brachyspira pilosicoli P43/6/78 ribose-phosphate pyrophosphokinase YP_007234619.1 1167301 D 1042417 CDS YP_007234620.1 431807722 14294861 1168281..1168877 1 NC_019908.1 COG1825 Ribosomal protein L25 (general stress protein Ctc); 50S ribosomal protein L25 1168877 14294861 BPP43_05585 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L25 YP_007234620.1 1168281 D 1042417 CDS YP_007234621.1 431807723 14294862 1168906..1169505 1 NC_019908.1 COG0193 Peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase 1169505 14294862 BPP43_05590 Brachyspira pilosicoli P43/6/78 peptidyl-tRNA hydrolase YP_007234621.1 1168906 D 1042417 CDS YP_007234622.1 431807724 14294863 1169502..1170098 1 NC_019908.1 COG0193 Peptidyl-tRNA hydrolase; peptidyl tRNA hydrolase 1170098 14294863 BPP43_05595 Brachyspira pilosicoli P43/6/78 peptidyl tRNA hydrolase YP_007234622.1 1169502 D 1042417 CDS YP_007234623.1 431807725 14294864 1170091..1170378 1 NC_019908.1 COG1359 Uncharacterized conserved protein; peptidyl-tRNA hydrolase 1170378 14294864 BPP43_05600 Brachyspira pilosicoli P43/6/78 peptidyl-tRNA hydrolase YP_007234623.1 1170091 D 1042417 CDS YP_007234624.1 431807726 14294865 1170450..1171517 1 NC_019908.1 COG1195 Recombinational DNA repair ATPase (RecF pathway); DNA replication and repair protein RecF 1171517 14294865 BPP43_05605 Brachyspira pilosicoli P43/6/78 DNA replication and repair protein RecF YP_007234624.1 1170450 D 1042417 CDS YP_007234625.1 431807727 14294866 1171599..1172063 1 NC_019908.1 COG2190 Phosphotransferase system IIA components; PTS-dependent protein II 1172063 14294866 BPP43_05610 Brachyspira pilosicoli P43/6/78 PTS-dependent protein II YP_007234625.1 1171599 D 1042417 CDS YP_007234626.1 431807728 14294867 complement(1172496..1173836) 1 NC_019908.1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; response regulatory protein AtoC 1173836 14294867 BPP43_05615 Brachyspira pilosicoli P43/6/78 response regulatory protein AtoC YP_007234626.1 1172496 R 1042417 CDS YP_007234627.1 431807729 14294868 complement(1173840..1175054) 1 NC_019908.1 COG0642 Signal transduction histidine kinase; sensory box histidine kinase 1175054 14294868 BPP43_05620 Brachyspira pilosicoli P43/6/78 sensory box histidine kinase YP_007234627.1 1173840 R 1042417 CDS YP_007234628.1 431807730 14294869 1175183..1175716 1 NC_019908.1 COG0242 N-formylmethionyl-tRNA deformylase; peptide deformylase 1175716 14294869 BPP43_05625 Brachyspira pilosicoli P43/6/78 peptide deformylase YP_007234628.1 1175183 D 1042417 CDS YP_007234629.1 431807731 14294870 1175725..1176405 1 NC_019908.1 COG0546 Predicted phosphatases; HAD-superfamily hydrolase 1176405 14294870 BPP43_05630 Brachyspira pilosicoli P43/6/78 HAD-superfamily hydrolase YP_007234629.1 1175725 D 1042417 CDS YP_007234630.1 431807732 14294871 complement(1176680..1177237) 1 NC_019908.1 COG0655 Multimeric flavodoxin WrbA; hypothetical protein 1177237 14294871 BPP43_05635 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234630.1 1176680 R 1042417 CDS YP_007234631.1 431807733 14294872 1177359..1177691 1 NC_019908.1 COG1733 Predicted transcriptional regulators; transcriptional regulator 1177691 14294872 BPP43_05640 Brachyspira pilosicoli P43/6/78 transcriptional regulator YP_007234631.1 1177359 D 1042417 CDS YP_007234632.1 431807734 14294873 complement(1180124..1181143) 1 NC_019908.1 COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation); poly-gamma-glutamic synthesis PgsA protein 1181143 14294873 BPP43_05655 Brachyspira pilosicoli P43/6/78 poly-gamma-glutamic synthesis PgsA protein YP_007234632.1 1180124 R 1042417 CDS YP_007234633.1 431807735 14294874 1181349..1182527 1 NC_019908.1 COG0739 Membrane proteins related to metalloendopeptidases; LysM domain/M23/M37 peptidase domain-containing protein 1182527 14294874 BPP43_05660 Brachyspira pilosicoli P43/6/78 LysM domain/M23/M37 peptidase domain-containing protein YP_007234633.1 1181349 D 1042417 CDS YP_007234634.1 431807736 14294875 complement(1182863..1183750) 1 NC_019908.1 COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain); hypothetical protein 1183750 14294875 BPP43_05665 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234634.1 1182863 R 1042417 CDS YP_007234635.1 431807737 14294876 complement(1184047..1184868) 1 NC_019908.1 COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB; ferredoxin 1184868 14294876 BPP43_05670 Brachyspira pilosicoli P43/6/78 ferredoxin YP_007234635.1 1184047 R 1042417 CDS YP_007234636.1 431807738 14294877 complement(1184884..1185462) 1 NC_019908.1 COG4657 Predicted NADH:ubiquinone oxidoreductase, subunit RnfA; NADH:ubiquinone oxidoreductase, RnfA subunit-like protein 1185462 14294877 BPP43_05675 Brachyspira pilosicoli P43/6/78 NADH:ubiquinone oxidoreductase, RnfA subunit-like protein YP_007234636.1 1184884 R 1042417 CDS YP_007234637.1 431807739 14294878 complement(1185468..1186115) 1 NC_019908.1 COG4660 Predicted NADH:ubiquinone oxidoreductase, subunit RnfE; RnfABCDGE type electron transport complex subunit E 1186115 14294878 BPP43_05680 Brachyspira pilosicoli P43/6/78 RnfABCDGE type electron transport complex subunit E YP_007234637.1 1185468 R 1042417 CDS YP_007234638.1 431807740 14294879 1186295..1187440 1 NC_019908.1 COG0263 Glutamate 5-kinase; glutamate-5-kinase 1187440 14294879 BPP43_05685 Brachyspira pilosicoli P43/6/78 glutamate-5-kinase YP_007234638.1 1186295 D 1042417 CDS YP_007234639.1 431807741 14294880 complement(1187597..1189891) 1 NC_019908.1 hypothetical protein 1189891 14294880 BPP43_05690 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234639.1 1187597 R 1042417 CDS YP_007234640.1 431807742 14294881 1190129..1190455 1 NC_019908.1 COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; aspartyl/glutamyl-tRNA amidotransferase subunit C 1190455 14294881 BPP43_05695 Brachyspira pilosicoli P43/6/78 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_007234640.1 1190129 D 1042417 CDS YP_007234641.1 431807743 14294882 1190490..1191224 1 NC_019908.1 COG0681 Signal peptidase I; signal peptidase I 1191224 14294882 BPP43_05700 Brachyspira pilosicoli P43/6/78 signal peptidase I YP_007234641.1 1190490 D 1042417 CDS YP_007234642.1 431807744 14294883 1191311..1191643 1 NC_019908.1 preprotein translocase subunit SecG 1191643 14294883 BPP43_05705 Brachyspira pilosicoli P43/6/78 preprotein translocase subunit SecG YP_007234642.1 1191311 D 1042417 CDS YP_007234643.1 431807745 14294884 complement(1191749..1192213) 1 NC_019908.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 1192213 14294884 BPP43_05710 Brachyspira pilosicoli P43/6/78 N-acetyltransferase GCN5 YP_007234643.1 1191749 R 1042417 CDS YP_007234644.1 431807746 14294885 complement(1192234..1193424) 1 NC_019908.1 COG0468 RecA/RadA recombinase; recA protein 1193424 14294885 BPP43_05715 Brachyspira pilosicoli P43/6/78 recA protein YP_007234644.1 1192234 R 1042417 CDS YP_007234645.1 431807747 14294886 1193632..1194597 1 NC_019908.1 hypothetical protein 1194597 14294886 BPP43_05720 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234645.1 1193632 D 1042417 CDS YP_007234646.1 431807748 14294887 1196094..1198055 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein B 1198055 14294887 BPP43_05735 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis protein B YP_007234646.1 1196094 D 1042417 CDS YP_007234647.1 431807749 14294888 1198317..1198895 1 NC_019908.1 hypothetical protein 1198895 14294888 BPP43_05740 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234647.1 1198317 D 1042417 CDS YP_007234648.1 431807750 14294889 1199084..1201360 1 NC_019908.1 COG2217 Cation transport ATPase; copper-transporting P-type ATPase 1201360 14294889 BPP43_05745 Brachyspira pilosicoli P43/6/78 copper-transporting P-type ATPase YP_007234648.1 1199084 D 1042417 CDS YP_007234649.1 431807751 14294890 1201900..1202553 1 NC_019908.1 hypothetical protein 1202553 14294890 BPP43_05750 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234649.1 1201900 D 1042417 CDS YP_007234650.1 431807752 14294891 1202920..1203429 1 NC_019908.1 COG0835 Chemotaxis signal transduction protein; chemotaxis signal transduction protein CheW 1203429 14294891 BPP43_05755 Brachyspira pilosicoli P43/6/78 chemotaxis signal transduction protein CheW YP_007234650.1 1202920 D 1042417 CDS YP_007234651.1 431807753 14294892 complement(1203426..1204007) 1 NC_019908.1 COG0212 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase 1204007 14294892 BPP43_05760 Brachyspira pilosicoli P43/6/78 5-formyltetrahydrofolate cyclo-ligase YP_007234651.1 1203426 R 1042417 CDS YP_007234652.1 431807754 14294893 complement(1204019..1204762) 1 NC_019908.1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PilZ domain-containing protein 1204762 14294893 BPP43_05765 Brachyspira pilosicoli P43/6/78 PilZ domain-containing protein YP_007234652.1 1204019 R 1042417 CDS YP_007234653.1 431807755 14294894 1204941..1205351 1 NC_019908.1 COG0824 Predicted thioesterase; thioesterase 1205351 14294894 BPP43_05770 Brachyspira pilosicoli P43/6/78 thioesterase YP_007234653.1 1204941 D 1042417 CDS YP_007234654.1 431807756 14294895 1205369..1205677 1 NC_019908.1 hypothetical protein 1205677 14294895 BPP43_05775 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234654.1 1205369 D 1042417 CDS YP_007234655.1 431807757 14294896 complement(1205693..1205809) 1 NC_019908.1 hypothetical protein 1205809 14294896 BPP43_05780 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234655.1 1205693 R 1042417 CDS YP_007234656.1 431807758 14294897 1205946..1206113 1 NC_019908.1 F0F1 ATP synthase subunit epsilon 1206113 14294897 BPP43_05785 Brachyspira pilosicoli P43/6/78 F0F1 ATP synthase subunit epsilon YP_007234656.1 1205946 D 1042417 CDS YP_007234657.1 431807759 14294898 1206214..1209693 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1209693 14294898 BPP43_05790 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234657.1 1206214 D 1042417 CDS YP_007234658.1 431807760 14294899 complement(1209797..1210771) 1 NC_019908.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 1210771 14294899 BPP43_05795 Brachyspira pilosicoli P43/6/78 aldo/keto reductase YP_007234658.1 1209797 R 1042417 CDS YP_007234659.1 431807761 14294900 1210937..1211518 1 NC_019908.1 hypothetical protein 1211518 14294900 BPP43_05800 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234659.1 1210937 D 1042417 CDS YP_007234660.1 431807762 14294901 1211558..1212274 1 NC_019908.1 COG2188 Transcriptional regulators; GntR family transcriptional regulator 1212274 14294901 BPP43_05805 Brachyspira pilosicoli P43/6/78 GntR family transcriptional regulator YP_007234660.1 1211558 D 1042417 CDS YP_007234661.1 431807763 14294902 1212379..1213938 1 NC_019908.1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; phosphotransferase system protein 1213938 14294902 BPP43_05810 Brachyspira pilosicoli P43/6/78 phosphotransferase system protein YP_007234661.1 1212379 D 1042417 CDS YP_007234662.1 431807764 14294903 1213958..1214797 1 NC_019908.1 COG0107 Imidazoleglycerol-phosphate synthase; hypothetical protein 1214797 14294903 BPP43_05815 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234662.1 1213958 D 1042417 CDS YP_007234663.1 431807765 14294904 1214975..1216810 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis sensory transducer 1216810 14294904 BPP43_05820 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis sensory transducer YP_007234663.1 1214975 D 1042417 CDS YP_007234664.1 431807766 14294905 1216883..1218505 1 NC_019908.1 COG1283 Na+/phosphate symporter; Na phosphate symporter 1218505 14294905 BPP43_05825 Brachyspira pilosicoli P43/6/78 Na phosphate symporter YP_007234664.1 1216883 D 1042417 CDS YP_007234665.1 431807767 14294906 complement(1218518..1219066) 1 NC_019908.1 COG2818 3-methyladenine DNA glycosylase; 3-methyladenine DNA glycosylase 1219066 14294906 BPP43_05830 Brachyspira pilosicoli P43/6/78 3-methyladenine DNA glycosylase YP_007234665.1 1218518 R 1042417 CDS YP_007234666.1 431807768 14294907 complement(1219356..1219862) 1 NC_019908.1 hypothetical protein 1219862 14294907 BPP43_05835 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234666.1 1219356 R 1042417 CDS YP_007234667.1 431807769 14294908 complement(1219859..1220728) 1 NC_019908.1 RNA polymerase sigma subunit RpoD 1220728 14294908 BPP43_05840 Brachyspira pilosicoli P43/6/78 RNA polymerase sigma subunit RpoD YP_007234667.1 1219859 R 1042417 CDS YP_007234668.1 431807770 14294909 complement(1220737..1221177) 1 NC_019908.1 hypothetical protein 1221177 14294909 BPP43_05845 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234668.1 1220737 R 1042417 CDS YP_007234669.1 431807771 14294910 complement(1221183..1222022) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1222022 14294910 BPP43_05850 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234669.1 1221183 R 1042417 CDS YP_007234670.1 431807772 14294911 complement(1221982..1222824) 1 NC_019908.1 hypothetical protein 1222824 14294911 BPP43_05855 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234670.1 1221982 R 1042417 CDS YP_007234671.1 431807773 14294912 complement(1222910..1224181) 1 NC_019908.1 COG3681 Uncharacterized conserved protein; hypothetical protein 1224181 14294912 BPP43_05860 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234671.1 1222910 R 1042417 CDS YP_007234672.1 431807774 14294913 1224458..1225606 1 NC_019908.1 COG1301 Na+/H+-dicarboxylate symporters; sodium:dicarboxylate symporter 1225606 14294913 BPP43_05865 Brachyspira pilosicoli P43/6/78 sodium:dicarboxylate symporter YP_007234672.1 1224458 D 1042417 CDS YP_007234673.1 431807775 14294914 complement(1225690..1226946) 1 NC_019908.1 COG0038 Chloride channel protein EriC; chloride channel protein ClcA 1226946 14294914 BPP43_05870 Brachyspira pilosicoli P43/6/78 chloride channel protein ClcA YP_007234673.1 1225690 R 1042417 CDS YP_007234674.1 431807776 14294915 complement(1227028..1228128) 1 NC_019908.1 COG0012 Predicted GTPase, probable translation factor; translation associated GTPase 1228128 14294915 BPP43_05875 Brachyspira pilosicoli P43/6/78 translation associated GTPase YP_007234674.1 1227028 R 1042417 CDS YP_007234675.1 431807777 14294916 1228409..1229395 1 NC_019908.1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit; rieske (2Fe-2S) domain-containing protein 1229395 14294916 BPP43_05880 Brachyspira pilosicoli P43/6/78 rieske (2Fe-2S) domain-containing protein YP_007234675.1 1228409 D 1042417 CDS YP_007234676.1 431807778 14294917 complement(1229460..1230869) 1 NC_019908.1 COG1115 Na+/alanine symporter; sodium:alanine symporter family protein 1230869 14294917 BPP43_05885 Brachyspira pilosicoli P43/6/78 sodium:alanine symporter family protein YP_007234676.1 1229460 R 1042417 CDS YP_007234677.1 431807779 14294918 complement(1231090..1232490) 1 NC_019908.1 COG1115 Na+/alanine symporter; amino acid carrier protein 1232490 14294918 BPP43_05890 Brachyspira pilosicoli P43/6/78 amino acid carrier protein YP_007234677.1 1231090 R 1042417 CDS YP_007234678.1 431807780 14294919 complement(1232629..1233798) 1 NC_019908.1 COG0416 Fatty acid/phospholipid biosynthesis enzyme; glycine/sarcosine/betaine reductase complex component C subunit alpha 1233798 14294919 BPP43_05895 Brachyspira pilosicoli P43/6/78 glycine/sarcosine/betaine reductase complex component C subunit alpha YP_007234678.1 1232629 R 1042417 CDS YP_007234679.1 431807781 14294920 complement(1233812..1236001) 1 NC_019908.1 COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; glycine/sarcosine/betaine reductase component B subunit alpha and beta GrdE 1236001 14294920 BPP43_05900 Brachyspira pilosicoli P43/6/78 glycine/sarcosine/betaine reductase component B subunit alpha and beta GrdE YP_007234679.1 1233812 R 1042417 CDS YP_007234680.1 431807782 14294921 complement(1236028..1236189) 1 NC_019908.1 hypothetical protein 1236189 14294921 BPP43_05905 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234680.1 1236028 R 1042417 CDS YP_007234681.1 431807783 14294922 complement(1236273..1237229) 1 NC_019908.1 COG0492 Thioredoxin reductase; thioredoxin-disulfide reductase 1237229 14294922 BPP43_05910 Brachyspira pilosicoli P43/6/78 thioredoxin-disulfide reductase YP_007234681.1 1236273 R 1042417 CDS YP_007234682.1 431807784 14294923 complement(1237252..1237554) 1 NC_019908.1 glycine reductase complex component GrdX 1237554 14294923 BPP43_05915 Brachyspira pilosicoli P43/6/78 glycine reductase complex component GrdX YP_007234682.1 1237252 R 1042417 CDS YP_007234683.1 431807785 14294924 complement(1237862..1239145) 1 NC_019908.1 COG0531 Amino acid transporters; amino acid permease 1239145 14294924 BPP43_05920 Brachyspira pilosicoli P43/6/78 amino acid permease YP_007234683.1 1237862 R 1042417 CDS YP_007234684.1 431807786 14294925 complement(1239196..1239924) 1 NC_019908.1 COG2071 Predicted glutamine amidotransferases; glutamine amidotransferase 1239924 14294925 BPP43_05925 Brachyspira pilosicoli P43/6/78 glutamine amidotransferase YP_007234684.1 1239196 R 1042417 CDS YP_007234685.1 431807787 14294926 1240067..1241296 1 NC_019908.1 COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; metal-dependent amidase aminoacylase carboxypeptidase 1241296 14294926 BPP43_05930 Brachyspira pilosicoli P43/6/78 metal-dependent amidase aminoacylase carboxypeptidase YP_007234685.1 1240067 D 1042417 CDS YP_007234686.1 431807788 14294927 1241390..1242994 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 1242994 14294927 BPP43_05935 Brachyspira pilosicoli P43/6/78 family 5 extracellular solute-binding protein YP_007234686.1 1241390 D 1042417 CDS YP_007234687.1 431807789 14294928 1243153..1244541 1 NC_019908.1 COG0534 Na+-driven multidrug efflux pump; MATE efflux family protein 1244541 14294928 BPP43_05940 Brachyspira pilosicoli P43/6/78 MATE efflux family protein YP_007234687.1 1243153 D 1042417 CDS YP_007234688.1 431807790 14294929 complement(1244597..1245052) 1 NC_019908.1 hypothetical protein 1245052 14294929 BPP43_05945 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234688.1 1244597 R 1042417 CDS YP_007234689.1 431807791 14294930 complement(1245056..1246999) 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis sensory transducer 1246999 14294930 BPP43_05950 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis sensory transducer YP_007234689.1 1245056 R 1042417 CDS YP_007234690.1 431807792 14294931 complement(1247014..1248951) 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis sensory transducer 1248951 14294931 BPP43_05955 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis sensory transducer YP_007234690.1 1247014 R 1042417 CDS YP_007234691.1 431807793 14294932 1249208..1251862 1 NC_019908.1 COG0525 Valyl-tRNA synthetase; valyl tRNA synthetase 1251862 14294932 BPP43_05960 Brachyspira pilosicoli P43/6/78 valyl tRNA synthetase YP_007234691.1 1249208 D 1042417 CDS YP_007234692.1 431807794 14294933 1251996..1252196 1 NC_019908.1 membrane-fusion protein 1252196 14294933 BPP43_05965 Brachyspira pilosicoli P43/6/78 membrane-fusion protein YP_007234692.1 1251996 D 1042417 CDS YP_007234693.1 431807795 14294934 1252427..1253014 1 NC_019908.1 membrane-fusion protein 1253014 14294934 BPP43_05970 Brachyspira pilosicoli P43/6/78 membrane-fusion protein YP_007234693.1 1252427 D 1042417 CDS YP_007234694.1 431807796 14294935 complement(1253080..1253346) 1 NC_019908.1 COG4115 Uncharacterized protein conserved in bacteria; hypothetical protein 1253346 14294935 BPP43_05975 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234694.1 1253080 R 1042417 CDS YP_007234695.1 431807797 14294936 complement(1253339..1253617) 1 NC_019908.1 COG3077 DNA-damage-inducible protein J; DNA damage inducible protein J 1253617 14294936 BPP43_05980 Brachyspira pilosicoli P43/6/78 DNA damage inducible protein J YP_007234695.1 1253339 R 1042417 CDS YP_007234696.1 431807798 14294937 complement(1253752..1255095) 1 NC_019908.1 COG0534 Na+-driven multidrug efflux pump; Na+-driven multidrug efflux pump 1255095 14294937 BPP43_05985 Brachyspira pilosicoli P43/6/78 Na+-driven multidrug efflux pump YP_007234696.1 1253752 R 1042417 CDS YP_007234697.1 431807799 14294938 complement(1255385..1256599) 1 NC_019908.1 hypothetical protein 1256599 14294938 BPP43_05990 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234697.1 1255385 R 1042417 CDS YP_007234698.1 431807800 14294939 complement(1256796..1257935) 1 NC_019908.1 hypothetical protein 1257935 14294939 BPP43_05995 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234698.1 1256796 R 1042417 CDS YP_007234699.1 431807801 14294940 complement(1257974..1260556) 1 NC_019908.1 hypothetical protein 1260556 14294940 BPP43_06000 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234699.1 1257974 R 1042417 CDS YP_007234700.1 431807802 14294941 complement(1260691..1261593) 1 NC_019908.1 COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; family 8 glycosyltransferase 1261593 14294941 BPP43_06005 Brachyspira pilosicoli P43/6/78 family 8 glycosyltransferase YP_007234700.1 1260691 R 1042417 CDS YP_007234701.1 431807803 14294942 complement(1261687..1264254) 1 NC_019908.1 hypothetical protein 1264254 14294942 BPP43_06010 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234701.1 1261687 R 1042417 CDS YP_007234702.1 431807804 14294944 1264540..1265175 1 NC_019908.1 hypothetical protein 1265175 14294944 BPP43_06015 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234702.1 1264540 D 1042417 CDS YP_007234703.1 431807805 14294945 1265262..1266089 1 NC_019908.1 COG4232 Thiol:disulfide interchange protein; thiol disulfide interchange protein DsbD like protein 1266089 14294945 BPP43_06020 Brachyspira pilosicoli P43/6/78 thiol disulfide interchange protein DsbD like protein YP_007234703.1 1265262 D 1042417 CDS YP_007234704.1 431807806 14294946 complement(1266170..1268323) 1 NC_019908.1 COG1196 Chromosome segregation ATPases; ATPase 1268323 14294946 BPP43_06025 Brachyspira pilosicoli P43/6/78 ATPase YP_007234704.1 1266170 R 1042417 CDS YP_007234705.1 431807807 14294947 complement(1268343..1269398) 1 NC_019908.1 COG0420 DNA repair exonuclease; exonuclease 1269398 14294947 BPP43_06030 Brachyspira pilosicoli P43/6/78 exonuclease YP_007234705.1 1268343 R 1042417 CDS YP_007234706.1 431807808 14294948 1269545..1270222 1 NC_019908.1 COG1059 Thermostable 8-oxoguanine DNA glycosylase; N-glycosylase/DNA lyase 1270222 14294948 BPP43_06035 Brachyspira pilosicoli P43/6/78 N-glycosylase/DNA lyase YP_007234706.1 1269545 D 1042417 CDS YP_007234707.1 431807809 14294949 1270239..1270769 1 NC_019908.1 COG1514 2'-5' RNA ligase; 2'-5' RNA ligase 1270769 14294949 BPP43_06040 Brachyspira pilosicoli P43/6/78 2'-5' RNA ligase YP_007234707.1 1270239 D 1042417 CDS YP_007234708.1 431807810 14294950 complement(1271001..1272746) 1 NC_019908.1 COG0168 Trk-type K+ transport systems, membrane components; cation transport protein TrkH 1272746 14294950 BPP43_06045 Brachyspira pilosicoli P43/6/78 cation transport protein TrkH YP_007234708.1 1271001 R 1042417 CDS YP_007234709.1 431807811 14294951 1272925..1273944 1 NC_019908.1 COG0016 Phenylalanyl-tRNA synthetase alpha subunit; phenylalanyl-tRNA synthetase subunit alpha 1273944 14294951 BPP43_06050 Brachyspira pilosicoli P43/6/78 phenylalanyl-tRNA synthetase subunit alpha YP_007234709.1 1272925 D 1042417 CDS YP_007234710.1 431807812 14294952 1273970..1276393 1 NC_019908.1 COG0073 EMAP domain; phenylalanyl-tRNA synthetase subunit alpha 1276393 14294952 BPP43_06055 Brachyspira pilosicoli P43/6/78 phenylalanyl-tRNA synthetase subunit alpha YP_007234710.1 1273970 D 1042417 CDS YP_007234711.1 431807813 14294953 1276414..1276812 1 NC_019908.1 COG2236 Predicted phosphoribosyltransferases; purine phosphoribosyltransferase 1276812 14294953 BPP43_06060 Brachyspira pilosicoli P43/6/78 purine phosphoribosyltransferase YP_007234711.1 1276414 D 1042417 CDS YP_007234712.1 431807814 14294954 1277314..1278024 1 NC_019908.1 COG1309 Transcriptional regulator; transcriptional regulator 1278024 14294954 BPP43_06065 Brachyspira pilosicoli P43/6/78 transcriptional regulator YP_007234712.1 1277314 D 1042417 CDS YP_007234713.1 431807815 14294955 1278050..1279504 1 NC_019908.1 outer membrane efflux protein 1279504 14294955 BPP43_06070 Brachyspira pilosicoli P43/6/78 outer membrane efflux protein YP_007234713.1 1278050 D 1042417 CDS YP_007234714.1 431807816 14294956 1279561..1282758 1 NC_019908.1 COG0841 Cation/multidrug efflux pump; acriflavin resistance protein heavy-metal efflux pump cation multidrug efflux pump 1282758 14294956 BPP43_06075 Brachyspira pilosicoli P43/6/78 acriflavin resistance protein heavy-metal efflux pump cation multidrug efflux pump YP_007234714.1 1279561 D 1042417 CDS YP_007234715.1 431807817 14294957 1282900..1283373 1 NC_019908.1 COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase 1283373 14294957 BPP43_06080 Brachyspira pilosicoli P43/6/78 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase YP_007234715.1 1282900 D 1042417 CDS YP_007234716.1 431807818 14294958 1283384..1284382 1 NC_019908.1 COG1562 Phytoene/squalene synthetase; squalene/phytoene synthase-like protein 1284382 14294958 BPP43_06085 Brachyspira pilosicoli P43/6/78 squalene/phytoene synthase-like protein YP_007234716.1 1283384 D 1042417 CDS YP_007234717.1 431807819 14294959 1284477..1284971 1 NC_019908.1 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog); integral membrane protein 1284971 14294959 BPP43_06090 Brachyspira pilosicoli P43/6/78 integral membrane protein YP_007234717.1 1284477 D 1042417 CDS YP_007234718.1 431807820 14294960 complement(1284993..1286330) 1 NC_019908.1 COG4206 Outer membrane cobalamin receptor protein; Ser/Thr protein kinase 1286330 14294960 BPP43_06095 Brachyspira pilosicoli P43/6/78 Ser/Thr protein kinase YP_007234718.1 1284993 R 1042417 CDS YP_007234719.1 431807821 14294961 1286470..1287081 1 NC_019908.1 hypothetical protein 1287081 14294961 BPP43_06100 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234719.1 1286470 D 1042417 CDS YP_007234720.1 431807822 14294962 1287084..1288472 1 NC_019908.1 COG2206 HD-GYP domain; hypothetical protein 1288472 14294962 BPP43_06105 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234720.1 1287084 D 1042417 CDS YP_007234721.1 431807823 14294963 complement(1289265..1290053) 1 NC_019908.1 COG0561 Predicted hydrolases of the HAD superfamily; hydrolase 1290053 14294963 BPP43_06120 Brachyspira pilosicoli P43/6/78 hydrolase YP_007234721.1 1289265 R 1042417 CDS YP_007234722.1 431807824 14294964 complement(1290099..1291052) 1 NC_019908.1 COG1079 Uncharacterized ABC-type transport system, permease component; inner membrane translocator 1291052 14294964 BPP43_06125 Brachyspira pilosicoli P43/6/78 inner membrane translocator YP_007234722.1 1290099 R 1042417 CDS YP_007234723.1 431807825 14294965 complement(1291096..1292217) 1 NC_019908.1 COG4603 ABC-type uncharacterized transport system, permease component; inner-membrane translocator 1292217 14294965 BPP43_06130 Brachyspira pilosicoli P43/6/78 inner-membrane translocator YP_007234723.1 1291096 R 1042417 CDS YP_007234724.1 431807826 14294966 complement(1292217..1293737) 1 NC_019908.1 COG3845 ABC-type uncharacterized transport systems, ATPase components; ABC transporter 1293737 14294966 BPP43_06135 Brachyspira pilosicoli P43/6/78 ABC transporter YP_007234724.1 1292217 R 1042417 CDS YP_007234725.1 431807827 14294967 complement(1293806..1294867) 1 NC_019908.1 COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein; basic membrane lipoprotein 1294867 14294967 BPP43_06140 Brachyspira pilosicoli P43/6/78 basic membrane lipoprotein YP_007234725.1 1293806 R 1042417 CDS YP_007234726.1 431807828 14294968 complement(1294929..1295999) 1 NC_019908.1 COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein; basic membrane lipoprotein 1295999 14294968 BPP43_06145 Brachyspira pilosicoli P43/6/78 basic membrane lipoprotein YP_007234726.1 1294929 R 1042417 CDS YP_007234727.1 431807829 14294969 complement(1296058..1296861) 1 NC_019908.1 COG2820 Uridine phosphorylase; uridine phosphorylase 1296861 14294969 BPP43_06150 Brachyspira pilosicoli P43/6/78 uridine phosphorylase YP_007234727.1 1296058 R 1042417 CDS YP_007234728.1 431807830 14294970 complement(1296870..1297670) 1 NC_019908.1 COG2820 Uridine phosphorylase; uridine phosphorylase 1297670 14294970 BPP43_06155 Brachyspira pilosicoli P43/6/78 uridine phosphorylase YP_007234728.1 1296870 R 1042417 CDS YP_007234729.1 431807831 14294971 complement(1297708..1298358) 1 NC_019908.1 COG0274 Deoxyribose-phosphate aldolase; deoxyribose phosphate aldolase 1298358 14294971 BPP43_06160 Brachyspira pilosicoli P43/6/78 deoxyribose phosphate aldolase YP_007234729.1 1297708 R 1042417 CDS YP_007234730.1 431807832 14294972 complement(1298452..1299807) 1 NC_019908.1 COG0534 Na+-driven multidrug efflux pump; cation efflux protein 1299807 14294972 BPP43_06165 Brachyspira pilosicoli P43/6/78 cation efflux protein YP_007234730.1 1298452 R 1042417 CDS YP_007234731.1 431807833 14294973 complement(1300127..1302631) 1 NC_019908.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; hemolysin B 1302631 14294973 BPP43_06170 Brachyspira pilosicoli P43/6/78 hemolysin B YP_007234731.1 1300127 R 1042417 CDS YP_007234732.1 431807834 14294974 complement(1302773..1303114) 1 NC_019908.1 hypothetical protein 1303114 14294974 BPP43_06175 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234732.1 1302773 R 1042417 CDS YP_007234733.1 431807835 14294975 complement(1303111..1303680) 1 NC_019908.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma-24 subunit 1303680 14294975 BPP43_06180 Brachyspira pilosicoli P43/6/78 RNA polymerase sigma-24 subunit YP_007234733.1 1303111 R 1042417 CDS YP_007234734.1 431807836 14294976 complement(1303741..1305411) 1 NC_019908.1 COG1219 ATP-dependent protease Clp, ATPase subunit; membrane-associated ATP-dependent Clp protease ATP-binding subunit 1305411 14294976 BPP43_06185 Brachyspira pilosicoli P43/6/78 membrane-associated ATP-dependent Clp protease ATP-binding subunit YP_007234734.1 1303741 R 1042417 CDS YP_007234735.1 431807837 14294977 complement(1305558..1306880) 1 NC_019908.1 COG0621 2-methylthioadenine synthetase; 2-methylthioadenine synthetase 1306880 14294977 BPP43_06190 Brachyspira pilosicoli P43/6/78 2-methylthioadenine synthetase YP_007234735.1 1305558 R 1042417 CDS YP_007234736.1 431807838 14294978 complement(1306943..1308301) 1 NC_019908.1 COG1426 Uncharacterized protein conserved in bacteria; hypothetical protein 1308301 14294978 BPP43_06195 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234736.1 1306943 R 1042417 CDS YP_007234737.1 431807839 14294979 complement(1308326..1308988) 1 NC_019908.1 COG2834 Outer membrane lipoprotein-sorting protein; hypothetical protein 1308988 14294979 BPP43_06200 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234737.1 1308326 R 1042417 CDS YP_007234738.1 431807840 14294980 1309281..1309673 1 NC_019908.1 hypothetical protein 1309673 14294980 BPP43_06205 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234738.1 1309281 D 1042417 CDS YP_007234739.1 431807841 14294981 1309688..1310107 1 NC_019908.1 hypothetical protein 1310107 14294981 BPP43_06210 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234739.1 1309688 D 1042417 CDS YP_007234740.1 431807842 14294982 1310214..1311194 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1311194 14294982 BPP43_06215 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234740.1 1310214 D 1042417 CDS YP_007234741.1 431807843 14294983 1311199..1313406 1 NC_019908.1 COG1747 Uncharacterized N-terminal domain of the transcription elongation factor GreA; transcript cleavage factor/hypothetical protein 1313406 14294983 BPP43_06220 Brachyspira pilosicoli P43/6/78 transcript cleavage factor/hypothetical protein YP_007234741.1 1311199 D 1042417 CDS YP_007234742.1 431807844 14294984 complement(1313807..1314553) 1 NC_019908.1 hypothetical protein 1314553 14294984 BPP43_06225 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234742.1 1313807 R 1042417 CDS YP_007234743.1 431807845 14294985 complement(1314574..1315236) 1 NC_019908.1 hypothetical protein 1315236 14294985 BPP43_06230 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234743.1 1314574 R 1042417 CDS YP_007234744.1 431807846 14294986 complement(1315309..1316127) 1 NC_019908.1 COG0084 Mg-dependent DNase; TatD protein 1316127 14294986 BPP43_06235 Brachyspira pilosicoli P43/6/78 TatD protein YP_007234744.1 1315309 R 1042417 CDS YP_007234745.1 431807847 14294987 complement(1316147..1316476) 1 NC_019908.1 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; histidine triad (HIT) family protein 1316476 14294987 BPP43_06240 Brachyspira pilosicoli P43/6/78 histidine triad (HIT) family protein YP_007234745.1 1316147 R 1042417 CDS YP_007234746.1 431807848 14294988 1316608..1317414 1 NC_019908.1 COG0428 Predicted divalent heavy-metal cations transporter; zinc transporter ZupT 1317414 14294988 BPP43_06245 Brachyspira pilosicoli P43/6/78 zinc transporter ZupT YP_007234746.1 1316608 D 1042417 CDS YP_007234747.1 431807849 14294989 complement(1318033..1318860) 1 NC_019908.1 COG1137 ABC-type (unclassified) transport system, ATPase component; ABC transporter ATP-binding protein 1318860 14294989 BPP43_06250 Brachyspira pilosicoli P43/6/78 ABC transporter ATP-binding protein YP_007234747.1 1318033 R 1042417 CDS YP_007234748.1 431807850 14294990 complement(1318890..1319426) 1 NC_019908.1 COG1528 Ferritin-like protein; non-heme iron-containing ferritin 1319426 14294990 BPP43_06255 Brachyspira pilosicoli P43/6/78 non-heme iron-containing ferritin YP_007234748.1 1318890 R 1042417 CDS YP_007234749.1 431807851 14294991 complement(1320253..1321287) 1 NC_019908.1 COG1879 ABC-type sugar transport system, periplasmic component; galactose glucose-binding protein 1321287 14294991 BPP43_06270 Brachyspira pilosicoli P43/6/78 galactose glucose-binding protein YP_007234749.1 1320253 R 1042417 CDS YP_007234750.1 431807852 14294992 complement(1321313..1322332) 1 NC_019908.1 COG1879 ABC-type sugar transport system, periplasmic component; galactose glucose-binding protein 1322332 14294992 BPP43_06275 Brachyspira pilosicoli P43/6/78 galactose glucose-binding protein YP_007234750.1 1321313 R 1042417 CDS YP_007234751.1 431807853 14294993 complement(1322386..1323348) 1 NC_019908.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 1323348 14294993 BPP43_06280 Brachyspira pilosicoli P43/6/78 oxidoreductase YP_007234751.1 1322386 R 1042417 CDS YP_007234752.1 431807854 14294994 1323545..1324654 1 NC_019908.1 COG0082 Chorismate synthase; chorismate synthase 1324654 14294994 BPP43_06285 Brachyspira pilosicoli P43/6/78 chorismate synthase YP_007234752.1 1323545 D 1042417 CDS YP_007234753.1 431807855 14294995 complement(1324850..1326562) 1 NC_019908.1 COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold; metal-dependent glycoprotease 1326562 14294995 BPP43_06290 Brachyspira pilosicoli P43/6/78 metal-dependent glycoprotease YP_007234753.1 1324850 R 1042417 CDS YP_007234754.1 431807856 14294996 complement(1326768..1327178) 1 NC_019908.1 hypothetical protein 1327178 14294996 BPP43_06295 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234754.1 1326768 R 1042417 CDS YP_007234755.1 431807857 14294997 complement(1327197..1328069) 1 NC_019908.1 COG2890 Methylase of polypeptide chain release factors; protein methyltransferase 1328069 14294997 BPP43_06300 Brachyspira pilosicoli P43/6/78 protein methyltransferase YP_007234755.1 1327197 R 1042417 CDS YP_007234756.1 431807858 14294998 1328410..1330281 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein B 1330281 14294998 BPP43_06305 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis protein B YP_007234756.1 1328410 D 1042417 CDS YP_007234757.1 431807859 14294999 1330309..1332051 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1332051 14294999 BPP43_06310 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234757.1 1330309 D 1042417 CDS YP_007234758.1 431807860 14295000 1332084..1333757 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1333757 14295000 BPP43_06315 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234758.1 1332084 D 1042417 CDS YP_007234759.1 431807861 14295001 complement(1333762..1335492) 1 NC_019908.1 COG1001 Adenine deaminase; adenine deaminase 1335492 14295001 BPP43_06320 Brachyspira pilosicoli P43/6/78 adenine deaminase YP_007234759.1 1333762 R 1042417 CDS YP_007234760.1 431807862 14295002 complement(1335556..1336758) 1 NC_019908.1 COG1479 Uncharacterized conserved protein; hypothetical protein 1336758 14295002 BPP43_06325 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234760.1 1335556 R 1042417 CDS YP_007234761.1 431807863 14295003 complement(1336766..1337281) 1 NC_019908.1 COG1479 Uncharacterized conserved protein; hypothetical protein 1337281 14295003 BPP43_06330 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234761.1 1336766 R 1042417 CDS YP_007234762.1 431807864 14295004 complement(1337352..1338803) 1 NC_019908.1 COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 1338803 14295004 BPP43_06335 Brachyspira pilosicoli P43/6/78 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B YP_007234762.1 1337352 R 1042417 CDS YP_007234763.1 431807865 14295006 1339076..1340029 1 NC_019908.1 COG0611 Thiamine monophosphate kinase; thiamine monophosphate kinase 1340029 14295006 BPP43_06340 Brachyspira pilosicoli P43/6/78 thiamine monophosphate kinase YP_007234763.1 1339076 D 1042417 CDS YP_007234764.1 431807866 14295007 complement(1340026..1341132) 1 NC_019908.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; beta-1, 3-galactosyltransferase 1341132 14295007 BPP43_06345 Brachyspira pilosicoli P43/6/78 beta-1, 3-galactosyltransferase YP_007234764.1 1340026 R 1042417 CDS YP_007234765.1 431807867 14295008 complement(1341151..1342377) 1 NC_019908.1 COG2195 Di- and tripeptidases; peptidase T 1342377 14295008 BPP43_06350 Brachyspira pilosicoli P43/6/78 peptidase T YP_007234765.1 1341151 R 1042417 CDS YP_007234766.1 431807868 14295009 1342503..1343786 1 NC_019908.1 hypothetical protein 1343786 14295009 BPP43_06355 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234766.1 1342503 D 1042417 CDS YP_007234767.1 431807869 14295010 complement(1343787..1345400) 1 NC_019908.1 hypothetical protein 1345400 14295010 BPP43_06360 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234767.1 1343787 R 1042417 CDS YP_007234768.1 431807870 14295011 complement(1345402..1346442) 1 NC_019908.1 COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain; thiamine biosynthesis protein 1346442 14295011 BPP43_06365 Brachyspira pilosicoli P43/6/78 thiamine biosynthesis protein YP_007234768.1 1345402 R 1042417 CDS YP_007234769.1 431807871 14295012 complement(1346994..1347704) 1 NC_019908.1 COG2738 Predicted Zn-dependent protease; peptidase membrane zinc metallopeptidase 1347704 14295012 BPP43_06370 Brachyspira pilosicoli P43/6/78 peptidase membrane zinc metallopeptidase YP_007234769.1 1346994 R 1042417 CDS YP_007234770.1 431807872 14295013 complement(1347782..1349626) 1 NC_019908.1 COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 1349626 14295013 BPP43_06375 Brachyspira pilosicoli P43/6/78 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_007234770.1 1347782 R 1042417 CDS YP_007234771.1 431807873 14295014 1349915..1350517 1 NC_019908.1 hypothetical protein 1350517 14295014 BPP43_06380 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234771.1 1349915 D 1042417 CDS YP_007234772.1 431807874 14295015 1350612..1351382 1 NC_019908.1 hypothetical protein 1351382 14295015 BPP43_06385 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234772.1 1350612 D 1042417 CDS YP_007234773.1 431807875 14295016 complement(1351632..1352039) 1 NC_019908.1 hypothetical protein 1352039 14295016 BPP43_06390 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234773.1 1351632 R 1042417 CDS YP_007234774.1 431807876 14295017 1352113..1352790 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1352790 14295017 BPP43_06395 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234774.1 1352113 D 1042417 CDS YP_007234775.1 431807877 14295018 complement(1352787..1353131) 1 NC_019908.1 hypothetical protein 1353131 14295018 BPP43_06400 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234775.1 1352787 R 1042417 CDS YP_007234776.1 431807878 14295019 complement(1353222..1353743) 1 NC_019908.1 hypothetical protein 1353743 14295019 BPP43_06405 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234776.1 1353222 R 1042417 CDS YP_007234777.1 431807879 14295020 complement(1353776..1354648) 1 NC_019908.1 COG1814 Uncharacterized membrane protein; ferritin 1354648 14295020 BPP43_06410 Brachyspira pilosicoli P43/6/78 ferritin YP_007234777.1 1353776 R 1042417 CDS YP_007234778.1 431807880 14295021 1354806..1355960 1 NC_019908.1 COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; N-acyl-L-amino acid amidohydrolase 1355960 14295021 BPP43_06415 Brachyspira pilosicoli P43/6/78 N-acyl-L-amino acid amidohydrolase YP_007234778.1 1354806 D 1042417 CDS YP_007234779.1 431807881 14295022 1355960..1356679 1 NC_019908.1 hypothetical protein 1356679 14295022 BPP43_06420 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234779.1 1355960 D 1042417 CDS YP_007234780.1 431807882 14295023 1356683..1357345 1 NC_019908.1 hypothetical protein 1357345 14295023 BPP43_06425 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234780.1 1356683 D 1042417 CDS YP_007234781.1 431807883 14295024 complement(1357419..1358135) 1 NC_019908.1 hypothetical protein 1358135 14295024 BPP43_06430 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234781.1 1357419 R 1042417 CDS YP_007234782.1 431807884 14295025 complement(1358270..1359436) 1 NC_019908.1 COG0784 FOG: CheY-like receiver; response regulator receiver modulated serine phosphatase 1359436 14295025 BPP43_06435 Brachyspira pilosicoli P43/6/78 response regulator receiver modulated serine phosphatase YP_007234782.1 1358270 R 1042417 CDS YP_007234783.1 431807885 14295026 complement(1360746..1362608) 1 NC_019908.1 COG0768 Cell division protein FtsI/penicillin-binding protein 2; peptidoglycan synthesis penicillin-binding protein 2 1362608 14295026 BPP43_06450 Brachyspira pilosicoli P43/6/78 peptidoglycan synthesis penicillin-binding protein 2 YP_007234783.1 1360746 R 1042417 CDS YP_007234784.1 431807886 14295027 complement(1362879..1364345) 1 NC_019908.1 COG0793 Periplasmic protease; carboxyl terminal protease 1364345 14295027 BPP43_06455 Brachyspira pilosicoli P43/6/78 carboxyl terminal protease YP_007234784.1 1362879 R 1042417 CDS YP_007234785.1 431807887 14295028 1364518..1365453 1 NC_019908.1 COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 1365453 14295028 BPP43_06460 Brachyspira pilosicoli P43/6/78 N-acetylmuramoyl-L-alanine amidase YP_007234785.1 1364518 D 1042417 CDS YP_007234786.1 431807888 14295029 complement(1365450..1366403) 1 NC_019908.1 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase 1366403 14295029 BPP43_06465 Brachyspira pilosicoli P43/6/78 transcriptional regulator/sugar kinase YP_007234786.1 1365450 R 1042417 CDS YP_007234787.1 431807889 14295030 1366557..1368347 1 NC_019908.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 1368347 14295030 BPP43_06470 Brachyspira pilosicoli P43/6/78 glycosyltransferase YP_007234787.1 1366557 D 1042417 CDS YP_007234788.1 431807890 14295031 complement(1368334..1368927) 1 NC_019908.1 COG2059 Chromate transport protein ChrA; chromate transport protein ChrA 1368927 14295031 BPP43_06475 Brachyspira pilosicoli P43/6/78 chromate transport protein ChrA YP_007234788.1 1368334 R 1042417 CDS YP_007234789.1 431807891 14295032 complement(1368930..1369514) 1 NC_019908.1 COG2059 Chromate transport protein ChrA; chromate transport protein 1369514 14295032 BPP43_06480 Brachyspira pilosicoli P43/6/78 chromate transport protein YP_007234789.1 1368930 R 1042417 CDS YP_007234790.1 431807892 14295033 complement(1369721..1370617) 1 NC_019908.1 hypothetical protein 1370617 14295033 BPP43_06485 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234790.1 1369721 R 1042417 CDS YP_007234791.1 431807893 14295034 1370863..1372482 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 1372482 14295034 BPP43_06490 Brachyspira pilosicoli P43/6/78 family 5 extracellular solute-binding protein YP_007234791.1 1370863 D 1042417 CDS YP_007234792.1 431807894 14295035 1372543..1373829 1 NC_019908.1 COG0281 Malic enzyme; malate dehydrogenase 1373829 14295035 BPP43_06495 Brachyspira pilosicoli P43/6/78 malate dehydrogenase YP_007234792.1 1372543 D 1042417 CDS YP_007234793.1 431807895 14295036 complement(1373919..1374314) 1 NC_019908.1 COG0706 Preprotein translocase subunit YidC; hypothetical protein 1374314 14295036 BPP43_06500 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234793.1 1373919 R 1042417 CDS YP_007234794.1 431807896 14295037 complement(1374392..1375429) 1 NC_019908.1 COG2021 Homoserine acetyltransferase; homoserine o-acetyltransferase 1375429 14295037 BPP43_06505 Brachyspira pilosicoli P43/6/78 homoserine o-acetyltransferase YP_007234794.1 1374392 R 1042417 CDS YP_007234795.1 431807897 14295038 complement(1375457..1376755) 1 NC_019908.1 COG2873 O-acetylhomoserine sulfhydrylase; O-acetylhomoserine-O-acetylserine sulfhydrylase 1376755 14295038 BPP43_06510 Brachyspira pilosicoli P43/6/78 O-acetylhomoserine-O-acetylserine sulfhydrylase YP_007234795.1 1375457 R 1042417 CDS YP_007234796.1 431807898 14295039 1377106..1377225 1 NC_019908.1 hypothetical protein 1377225 14295039 BPP43_06515 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234796.1 1377106 D 1042417 CDS YP_007234797.1 431807899 14295040 1377230..1378369 1 NC_019908.1 hypothetical protein 1378369 14295040 BPP43_06520 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234797.1 1377230 D 1042417 CDS YP_007234798.1 431807900 14295041 1378366..1379349 1 NC_019908.1 hypothetical protein 1379349 14295041 BPP43_06525 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234798.1 1378366 D 1042417 CDS YP_007234799.1 431807901 14295042 1379429..1379953 1 NC_019908.1 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; bifunctional methionine sulfoxide reductase B/A protein 1379953 14295042 BPP43_06530 Brachyspira pilosicoli P43/6/78 bifunctional methionine sulfoxide reductase B/A protein YP_007234799.1 1379429 D 1042417 CDS YP_007234800.1 431807902 14295043 1379971..1380459 1 NC_019908.1 COG0225 Peptide methionine sulfoxide reductase; peptide methionine sulfoxide reductase 1380459 14295043 BPP43_06535 Brachyspira pilosicoli P43/6/78 peptide methionine sulfoxide reductase YP_007234800.1 1379971 D 1042417 CDS YP_007234801.1 431807903 14295044 complement(1380910..1381050) 1 NC_019908.1 hypothetical protein 1381050 14295044 BPP43_06540 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234801.1 1380910 R 1042417 CDS YP_007234802.1 431807904 14295045 complement(1381057..1382079) 1 NC_019908.1 COG4211 ABC-type glucose/galactose transport system, permease component; beta-methylgalactoside transporter inner membrane protein 1382079 mglC 14295045 mglC Brachyspira pilosicoli P43/6/78 beta-methylgalactoside transporter inner membrane protein YP_007234802.1 1381057 R 1042417 CDS YP_007234803.1 431807905 14295046 complement(1382102..1383604) 1 NC_019908.1 COG1129 ABC-type sugar transport system, ATPase component; galactose/methyl galaxtoside transporter ATP-binding protein 1383604 14295046 BPP43_06550 Brachyspira pilosicoli P43/6/78 galactose/methyl galaxtoside transporter ATP-binding protein YP_007234803.1 1382102 R 1042417 CDS YP_007234804.1 431807906 14295047 complement(1383715..1384767) 1 NC_019908.1 COG1879 ABC-type sugar transport system, periplasmic component; galactose glucose-binding protein 1384767 14295047 BPP43_06555 Brachyspira pilosicoli P43/6/78 galactose glucose-binding protein YP_007234804.1 1383715 R 1042417 CDS YP_007234805.1 431807907 14295048 complement(1384884..1385054) 1 NC_019908.1 hypothetical protein 1385054 14295048 BPP43_06560 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234805.1 1384884 R 1042417 CDS YP_007234806.1 431807908 14295049 1385068..1385256 1 NC_019908.1 hypothetical protein 1385256 14295049 BPP43_06565 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234806.1 1385068 D 1042417 CDS YP_007234807.1 431807909 14295050 complement(1385302..1386198) 1 NC_019908.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S RNA-specific pseudouridylate synthase 1386198 14295050 BPP43_06570 Brachyspira pilosicoli P43/6/78 23S RNA-specific pseudouridylate synthase YP_007234807.1 1385302 R 1042417 CDS YP_007234808.1 431807910 14295051 complement(1386202..1386756) 1 NC_019908.1 COG0597 Lipoprotein signal peptidase; lipoprotein signal peptidase 1386756 14295051 BPP43_06575 Brachyspira pilosicoli P43/6/78 lipoprotein signal peptidase YP_007234808.1 1386202 R 1042417 CDS YP_007234809.1 431807911 14295052 1386921..1387409 1 NC_019908.1 COG0669 Phosphopantetheine adenylyltransferase; phosphopantetheine adenylyltransferase 1387409 14295052 BPP43_06580 Brachyspira pilosicoli P43/6/78 phosphopantetheine adenylyltransferase YP_007234809.1 1386921 D 1042417 CDS YP_007234810.1 431807912 14295053 1387451..1388761 1 NC_019908.1 COG0621 2-methylthioadenine synthetase; 2-methylthioadenine synthetase 1388761 14295053 BPP43_06585 Brachyspira pilosicoli P43/6/78 2-methylthioadenine synthetase YP_007234810.1 1387451 D 1042417 CDS YP_007234811.1 431807913 14295054 1388872..1389429 1 NC_019908.1 COG3880 Uncharacterized protein with conserved CXXC pairs; UvrB/UvrC protein 1389429 14295054 BPP43_06590 Brachyspira pilosicoli P43/6/78 UvrB/UvrC protein YP_007234811.1 1388872 D 1042417 CDS YP_007234812.1 431807914 14295055 1389416..1390408 1 NC_019908.1 COG3869 Arginine kinase; ATP:guanido phosphotransferase domain-containing protein 1390408 14295055 BPP43_06595 Brachyspira pilosicoli P43/6/78 ATP:guanido phosphotransferase domain-containing protein YP_007234812.1 1389416 D 1042417 CDS YP_007234813.1 431807915 14295056 complement(1390443..1390853) 1 NC_019908.1 hypothetical protein 1390853 14295056 BPP43_06600 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234813.1 1390443 R 1042417 CDS YP_007234814.1 431807916 14295057 complement(1390941..1391717) 1 NC_019908.1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; ferredoxin 1391717 14295057 BPP43_06605 Brachyspira pilosicoli P43/6/78 ferredoxin YP_007234814.1 1390941 R 1042417 CDS YP_007234815.1 431807917 14295058 complement(1391808..1392245) 1 NC_019908.1 COG0335 Ribosomal protein L19; 50S ribosomal protein L19 1392245 14295058 BPP43_06610 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L19 YP_007234815.1 1391808 R 1042417 CDS YP_007234816.1 431807918 14295059 1392466..1393365 1 NC_019908.1 COG0739 Membrane proteins related to metalloendopeptidases; peptidase 1393365 14295059 BPP43_06615 Brachyspira pilosicoli P43/6/78 peptidase YP_007234816.1 1392466 D 1042417 CDS YP_007234817.1 431807919 14295060 1393349..1393567 1 NC_019908.1 hypothetical protein 1393567 14295060 BPP43_06620 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234817.1 1393349 D 1042417 CDS YP_007234818.1 431807920 14295061 1393591..1394790 1 NC_019908.1 COG1488 Nicotinic acid phosphoribosyltransferase; nicotinate phosphoribosyltransferase 1394790 14295061 BPP43_06625 Brachyspira pilosicoli P43/6/78 nicotinate phosphoribosyltransferase YP_007234818.1 1393591 D 1042417 CDS YP_007234819.1 431807921 14295062 1394796..1395626 1 NC_019908.1 hypothetical protein 1395626 14295062 BPP43_06630 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234819.1 1394796 D 1042417 CDS YP_007234820.1 431807922 14295063 1395695..1396696 1 NC_019908.1 hypothetical protein 1396696 14295063 BPP43_06635 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234820.1 1395695 D 1042417 CDS YP_007234821.1 431807923 14295064 1396702..1397526 1 NC_019908.1 hypothetical protein 1397526 14295064 BPP43_06640 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234821.1 1396702 D 1042417 CDS YP_007234822.1 431807924 14295065 complement(1397529..1398599) 1 NC_019908.1 COG0836 Mannose-1-phosphate guanylyltransferase; mannose-1-phosphate guanylyltransferase 1398599 14295065 BPP43_06645 Brachyspira pilosicoli P43/6/78 mannose-1-phosphate guanylyltransferase YP_007234822.1 1397529 R 1042417 CDS YP_007234823.1 431807925 14295066 1398798..1400000 1 NC_019908.1 COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; phosphopantothenoylcysteine decarboxylase phosphopantothenate cysteine ligase 1400000 14295066 BPP43_06650 Brachyspira pilosicoli P43/6/78 phosphopantothenoylcysteine decarboxylase phosphopantothenate cysteine ligase YP_007234823.1 1398798 D 1042417 CDS YP_007234824.1 431807926 14295067 1400033..1400740 1 NC_019908.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter-like protein 1400740 14295067 BPP43_06655 Brachyspira pilosicoli P43/6/78 ABC transporter-like protein YP_007234824.1 1400033 D 1042417 CDS YP_007234825.1 431807927 14295068 1400768..1403083 1 NC_019908.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease 1403083 14295068 BPP43_06660 Brachyspira pilosicoli P43/6/78 antimicrobial peptide ABC transporter permease YP_007234825.1 1400768 D 1042417 CDS YP_007234826.1 431807928 14295069 1403182..1403310 1 NC_019908.1 hypothetical protein 1403310 14295069 BPP43_06665 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234826.1 1403182 D 1042417 CDS YP_007234827.1 431807929 14295070 complement(1403453..1404715) 1 NC_019908.1 COG0612 Predicted Zn-dependent peptidases; peptidase M16 domain-containing protein 1404715 14295070 BPP43_06670 Brachyspira pilosicoli P43/6/78 peptidase M16 domain-containing protein YP_007234827.1 1403453 R 1042417 CDS YP_007234828.1 431807930 14295071 1405454..1406614 1 NC_019908.1 COG1015 Phosphopentomutase; phosphopentomutase 1406614 14295071 BPP43_06685 Brachyspira pilosicoli P43/6/78 phosphopentomutase YP_007234828.1 1405454 D 1042417 CDS YP_007234829.1 431807931 14295072 complement(1406719..1406829) 1 NC_019908.1 hypothetical protein 1406829 14295072 BPP43_06690 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234829.1 1406719 R 1042417 CDS YP_007234830.1 431807932 14295073 complement(1407231..1407776) 1 NC_019908.1 hypothetical protein 1407776 14295073 BPP43_06695 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234830.1 1407231 R 1042417 CDS YP_007234831.1 431807933 14295074 complement(1407829..1408488) 1 NC_019908.1 COG1309 Transcriptional regulator; transcriptional regulator 1408488 14295074 BPP43_06700 Brachyspira pilosicoli P43/6/78 transcriptional regulator YP_007234831.1 1407829 R 1042417 CDS YP_007234832.1 431807934 14295075 1408517..1410403 1 NC_019908.1 COG2015 Alkyl sulfatase and related hydrolases; Alkyl sulfatase-related hydrolase 1410403 14295075 BPP43_06705 Brachyspira pilosicoli P43/6/78 Alkyl sulfatase-related hydrolase YP_007234832.1 1408517 D 1042417 CDS YP_007234833.1 431807935 14295076 complement(1410484..1411242) 1 NC_019908.1 COG0561 Predicted hydrolases of the HAD superfamily; HAD-superfamily hydrolase 1411242 14295076 BPP43_06710 Brachyspira pilosicoli P43/6/78 HAD-superfamily hydrolase YP_007234833.1 1410484 R 1042417 CDS YP_007234834.1 431807936 14295077 complement(1411245..1411661) 1 NC_019908.1 COG0432 Uncharacterized conserved protein; hypothetical protein 1411661 14295077 BPP43_06715 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234834.1 1411245 R 1042417 CDS YP_007234835.1 431807937 14295078 1411936..1412208 1 NC_019908.1 COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; TRX Fd NuoE, TRX-like (2Fe-2S) ferredoxin (Fd) family, DH:ubiquinone oxidoreductase (Nuo) subunit E subfamily protein 1412208 14295078 BPP43_06720 Brachyspira pilosicoli P43/6/78 TRX Fd NuoE, TRX-like (2Fe-2S) ferredoxin (Fd) family, DH:ubiquinone oxidoreductase (Nuo) subunit E subfamily protein YP_007234835.1 1411936 D 1042417 CDS YP_007234836.1 431807938 14295079 1412205..1413341 1 NC_019908.1 COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; NADH dehydrogenase 1413341 14295079 BPP43_06725 Brachyspira pilosicoli P43/6/78 NADH dehydrogenase YP_007234836.1 1412205 D 1042417 CDS YP_007234837.1 431807939 14295080 1413360..1414724 1 NC_019908.1 COG3383 Uncharacterized anaerobic dehydrogenase; ferrodoxin 1414724 14295080 BPP43_06730 Brachyspira pilosicoli P43/6/78 ferrodoxin YP_007234837.1 1413360 D 1042417 CDS YP_007234838.1 431807940 14295081 1414788..1416356 1 NC_019908.1 COG0578 Glycerol-3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase 1416356 14295081 BPP43_06735 Brachyspira pilosicoli P43/6/78 glycerol-3-phosphate dehydrogenase YP_007234838.1 1414788 D 1042417 CDS YP_007234839.1 431807941 14295082 1416567..1417034 1 NC_019908.1 hypothetical protein 1417034 14295082 BPP43_06740 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234839.1 1416567 D 1042417 CDS YP_007234840.1 431807942 14295083 complement(1417426..1419087) 1 NC_019908.1 COG2759 Formyltetrahydrofolate synthetase; formate-tetrahydrofolate ligase 1419087 14295083 BPP43_06745 Brachyspira pilosicoli P43/6/78 formate-tetrahydrofolate ligase YP_007234840.1 1417426 R 1042417 CDS YP_007234841.1 431807943 14295084 complement(1419438..1421609) 1 NC_019908.1 COG0608 Single-stranded DNA-specific exonuclease; single-stranded-DNA-specific exonuclease 1421609 14295084 BPP43_06750 Brachyspira pilosicoli P43/6/78 single-stranded-DNA-specific exonuclease YP_007234841.1 1419438 R 1042417 CDS YP_007234842.1 431807944 14295085 1423443..1424519 1 NC_019908.1 COG0216 Protein chain release factor A; peptide chain release factor 1 1424519 14295085 BPP43_06765 Brachyspira pilosicoli P43/6/78 peptide chain release factor 1 YP_007234842.1 1423443 D 1042417 CDS YP_007234843.1 431807945 14295086 1424529..1425233 1 NC_019908.1 hypothetical protein 1425233 14295086 BPP43_06770 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234843.1 1424529 D 1042417 CDS YP_007234844.1 431807946 14295087 1425244..1426680 1 NC_019908.1 COG0535 Predicted Fe-S oxidoreductases; radical SAM protein 1426680 14295087 BPP43_06775 Brachyspira pilosicoli P43/6/78 radical SAM protein YP_007234844.1 1425244 D 1042417 CDS YP_007234845.1 431807947 14295088 1426699..1427124 1 NC_019908.1 hypothetical protein 1427124 14295088 BPP43_06780 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234845.1 1426699 D 1042417 CDS YP_007234846.1 431807948 14295089 complement(1427121..1428107) 1 NC_019908.1 COG1209 dTDP-glucose pyrophosphorylase; glucose-1-phosphate thymidylyltransferase 1428107 14295089 BPP43_06785 Brachyspira pilosicoli P43/6/78 glucose-1-phosphate thymidylyltransferase YP_007234846.1 1427121 R 1042417 CDS YP_007234847.1 431807949 14295090 complement(1428176..1428730) 1 NC_019908.1 COG0693 Putative intracellular protease/amidase; PfpI domain-containing protein 1428730 14295090 BPP43_06790 Brachyspira pilosicoli P43/6/78 PfpI domain-containing protein YP_007234847.1 1428176 R 1042417 CDS YP_007234848.1 431807950 14295091 complement(1428971..1429837) 1 NC_019908.1 COG1466 DNA polymerase III, delta subunit; DNA polymerase III subunit delta 1429837 14295091 BPP43_06795 Brachyspira pilosicoli P43/6/78 DNA polymerase III subunit delta YP_007234848.1 1428971 R 1042417 CDS YP_007234849.1 431807951 14295092 complement(1429847..1430269) 1 NC_019908.1 hypothetical protein 1430269 14295092 BPP43_06800 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234849.1 1429847 R 1042417 CDS YP_007234850.1 431807952 14295093 1430460..1430987 1 NC_019908.1 hypothetical protein 1430987 14295093 BPP43_06805 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234850.1 1430460 D 1042417 CDS YP_007234851.1 431807953 14295094 1431044..1431979 1 NC_019908.1 hypothetical protein 1431979 14295094 BPP43_06810 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234851.1 1431044 D 1042417 CDS YP_007234852.1 431807954 14295095 1431989..1432765 1 NC_019908.1 hypothetical protein 1432765 14295095 BPP43_06815 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234852.1 1431989 D 1042417 CDS YP_007234853.1 431807955 14295096 1432795..1433412 1 NC_019908.1 tia invasion determinant 1433412 14295096 BPP43_06820 Brachyspira pilosicoli P43/6/78 tia invasion determinant YP_007234853.1 1432795 D 1042417 CDS YP_007234854.1 431807956 14295097 1433422..1434018 1 NC_019908.1 tia invasion determinant 1434018 14295097 BPP43_06825 Brachyspira pilosicoli P43/6/78 tia invasion determinant YP_007234854.1 1433422 D 1042417 CDS YP_007234855.1 431807957 14295098 1433987..1434283 1 NC_019908.1 COG1872 Uncharacterized conserved protein; hypothetical protein 1434283 14295098 BPP43_06830 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234855.1 1433987 D 1042417 CDS YP_007234856.1 431807958 14295099 complement(1434453..1437233) 1 NC_019908.1 trep protein 1437233 14295099 BPP43_06835 Brachyspira pilosicoli P43/6/78 trep protein YP_007234856.1 1434453 R 1042417 CDS YP_007234857.1 431807959 14295100 complement(1437272..1437730) 1 NC_019908.1 COG2703 Hemerythrin; hemerythrin 1437730 14295100 BPP43_06840 Brachyspira pilosicoli P43/6/78 hemerythrin YP_007234857.1 1437272 R 1042417 CDS YP_007234858.1 431807960 14295101 complement(1437848..1438297) 1 NC_019908.1 COG2703 Hemerythrin; hemerythrin 1438297 14295101 BPP43_06845 Brachyspira pilosicoli P43/6/78 hemerythrin YP_007234858.1 1437848 R 1042417 CDS YP_007234859.1 431807961 14295102 complement(1438565..1439860) 1 NC_019908.1 COG0148 Enolase; phosphopyruvate hydratase 1439860 14295102 BPP43_06850 Brachyspira pilosicoli P43/6/78 phosphopyruvate hydratase YP_007234859.1 1438565 R 1042417 CDS YP_007234860.1 431807962 14295103 complement(1439954..1440847) 1 NC_019908.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; family 2 glycosyltransferase 1440847 14295103 BPP43_06855 Brachyspira pilosicoli P43/6/78 family 2 glycosyltransferase YP_007234860.1 1439954 R 1042417 CDS YP_007234861.1 431807963 14295104 complement(1440847..1442790) 1 NC_019908.1 hypothetical protein 1442790 14295104 BPP43_06860 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234861.1 1440847 R 1042417 CDS YP_007234862.1 431807964 14295105 complement(1442997..1445600) 1 NC_019908.1 COG1012 NAD-dependent aldehyde dehydrogenases; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1445600 14295105 BPP43_06865 Brachyspira pilosicoli P43/6/78 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_007234862.1 1442997 R 1042417 CDS YP_007234863.1 431807965 14295106 1445833..1446702 1 NC_019908.1 COG0752 Glycyl-tRNA synthetase, alpha subunit; glycyl-tRNA synthetase subunit alpha 1446702 14295106 BPP43_06870 Brachyspira pilosicoli P43/6/78 glycyl-tRNA synthetase subunit alpha YP_007234863.1 1445833 D 1042417 CDS YP_007234864.1 431807966 14295107 complement(1446930..1447994) 1 NC_019908.1 COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase 1447994 14295107 BPP43_06875 Brachyspira pilosicoli P43/6/78 Glu/Leu/Phe/Val dehydrogenase YP_007234864.1 1446930 R 1042417 CDS YP_007234865.1 431807967 14295108 complement(1448186..1449544) 1 NC_019908.1 COG0402 Cytosine deaminase and related metal-dependent hydrolases; hydroxydechloroatrazine ethylaminohydrolase 1449544 14295108 BPP43_06880 Brachyspira pilosicoli P43/6/78 hydroxydechloroatrazine ethylaminohydrolase YP_007234865.1 1448186 R 1042417 CDS YP_007234866.1 431807968 14295109 1449979..1450734 1 NC_019908.1 hypothetical protein 1450734 14295109 BPP43_06885 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234866.1 1449979 D 1042417 CDS YP_007234867.1 431807969 14295110 1450756..1451382 1 NC_019908.1 COG0491 Zn-dependent hydrolases, including glyoxylases; beta lactamase domain-containing protein 1451382 14295110 BPP43_06890 Brachyspira pilosicoli P43/6/78 beta lactamase domain-containing protein YP_007234867.1 1450756 D 1042417 CDS YP_007234868.1 431807970 14295111 complement(1451804..1453006) 1 NC_019908.1 COG0687 Spermidine/putrescine-binding periplasmic protein; spermidine/putrescine transport ATP-binding protein PotD 1453006 14295111 BPP43_06895 Brachyspira pilosicoli P43/6/78 spermidine/putrescine transport ATP-binding protein PotD YP_007234868.1 1451804 R 1042417 CDS YP_007234869.1 431807971 14295112 complement(1453031..1453843) 1 NC_019908.1 COG1177 ABC-type spermidine/putrescine transport system, permease component II; spermidine/putrescine transport transport ATP-binding protein PotC 1453843 14295112 BPP43_06900 Brachyspira pilosicoli P43/6/78 spermidine/putrescine transport transport ATP-binding protein PotC YP_007234869.1 1453031 R 1042417 CDS YP_007234870.1 431807972 14295113 complement(1453840..1454655) 1 NC_019908.1 COG1176 ABC-type spermidine/putrescine transport system, permease component I; spermidine/putrescine transport ATP-binding protein PotB 1454655 14295113 BPP43_06905 Brachyspira pilosicoli P43/6/78 spermidine/putrescine transport ATP-binding protein PotB YP_007234870.1 1453840 R 1042417 CDS YP_007234871.1 431807973 14295114 complement(1454652..1455710) 1 NC_019908.1 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine transport ATP-binding protein potA 1455710 14295114 BPP43_06910 Brachyspira pilosicoli P43/6/78 spermidine/putrescine transport ATP-binding protein potA YP_007234871.1 1454652 R 1042417 CDS YP_007234872.1 431807974 14295115 1456168..1456659 1 NC_019908.1 hypothetical protein 1456659 14295115 BPP43_06915 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234872.1 1456168 D 1042417 CDS YP_007234873.1 431807975 14295116 complement(1456684..1458045) 1 NC_019908.1 COG0534 Na+-driven multidrug efflux pump; Na+-driven multidrug efflux pump 1458045 14295116 BPP43_06920 Brachyspira pilosicoli P43/6/78 Na+-driven multidrug efflux pump YP_007234873.1 1456684 R 1042417 CDS YP_007234874.1 431807976 14295117 complement(1458072..1458515) 1 NC_019908.1 hypothetical protein 1458515 14295117 BPP43_06925 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234874.1 1458072 R 1042417 CDS YP_007234875.1 431807977 14295118 1458701..1459747 1 NC_019908.1 COG0681 Signal peptidase I; leader peptidase/signal peptidase I 1459747 14295118 BPP43_06930 Brachyspira pilosicoli P43/6/78 leader peptidase/signal peptidase I YP_007234875.1 1458701 D 1042417 CDS YP_007234876.1 431807978 14295119 1459761..1461404 1 NC_019908.1 hypothetical protein 1461404 14295119 BPP43_06935 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234876.1 1459761 D 1042417 CDS YP_007234877.1 431807979 14295120 1461443..1462519 1 NC_019908.1 COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1462519 14295120 BPP43_06940 Brachyspira pilosicoli P43/6/78 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_007234877.1 1461443 D 1042417 CDS YP_007234878.1 431807980 14295121 1462591..1465545 1 NC_019908.1 COG3857 ATP-dependent nuclease, subunit B; ATP-dependent nuclease subunit B-like protein 1465545 14295121 BPP43_06945 Brachyspira pilosicoli P43/6/78 ATP-dependent nuclease subunit B-like protein YP_007234878.1 1462591 D 1042417 CDS YP_007234879.1 431807981 14295122 complement(1465611..1466507) 1 NC_019908.1 COG0500 SAM-dependent methyltransferases; methyltransferase 1466507 14295122 BPP43_06950 Brachyspira pilosicoli P43/6/78 methyltransferase YP_007234879.1 1465611 R 1042417 CDS YP_007234880.1 431807982 14295123 complement(1468024..1468572) 1 NC_019908.1 hypothetical protein 1468572 14295123 BPP43_06965 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234880.1 1468024 R 1042417 CDS YP_007234881.1 431807983 14295124 complement(1468726..1469664) 1 NC_019908.1 COG0492 Thioredoxin reductase; thioredoxin-disulfide reductase 1469664 14295124 BPP43_06970 Brachyspira pilosicoli P43/6/78 thioredoxin-disulfide reductase YP_007234881.1 1468726 R 1042417 CDS YP_007234882.1 431807984 14295125 complement(1469750..1471099) 1 NC_019908.1 COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen; hypothetical protein 1471099 14295125 BPP43_06975 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234882.1 1469750 R 1042417 CDS YP_007234883.1 431807985 14295126 1471380..1472891 1 NC_019908.1 hypothetical protein 1472891 14295126 BPP43_06980 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234883.1 1471380 D 1042417 CDS YP_007234884.1 431807986 14295127 1472968..1473279 1 NC_019908.1 COG1555 DNA uptake protein and related DNA-binding proteins; hypothetical protein 1473279 14295127 BPP43_06985 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234884.1 1472968 D 1042417 CDS YP_007234885.1 431807987 14295128 1473282..1476797 1 NC_019908.1 hypothetical protein 1476797 14295128 BPP43_06990 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234885.1 1473282 D 1042417 CDS YP_007234886.1 431807988 14295129 1476745..1478553 1 NC_019908.1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); hypothetical protein 1478553 14295129 BPP43_06995 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234886.1 1476745 D 1042417 CDS YP_007234887.1 431807989 14295130 complement(1478550..1479077) 1 NC_019908.1 COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; uracil phosphoribosyltransferase 1479077 14295130 BPP43_07000 Brachyspira pilosicoli P43/6/78 uracil phosphoribosyltransferase YP_007234887.1 1478550 R 1042417 CDS YP_007234888.1 431807990 14295131 1479317..1479862 1 NC_019908.1 COG1580 Flagellar basal body-associated protein; endoflagellar basal body-associated protein 1479862 14295131 BPP43_07005 Brachyspira pilosicoli P43/6/78 endoflagellar basal body-associated protein YP_007234888.1 1479317 D 1042417 CDS YP_007234889.1 431807991 14295132 1479893..1480924 1 NC_019908.1 COG1868 Flagellar motor switch protein; flagellar motor switch protein FliM 1480924 fliM 14295132 fliM Brachyspira pilosicoli P43/6/78 flagellar motor switch protein FliM YP_007234889.1 1479893 D 1042417 CDS YP_007234890.1 431807992 14295133 1480929..1481975 1 NC_019908.1 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation; flagellar motor switch protein FliN 1481975 14295133 BPP43_07015 Brachyspira pilosicoli P43/6/78 flagellar motor switch protein FliN YP_007234890.1 1480929 D 1042417 CDS YP_007234891.1 431807993 14295134 complement(1482561..1483103) 1 NC_019908.1 hypothetical protein 1483103 14295134 BPP43_07020 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234891.1 1482561 R 1042417 CDS YP_007234892.1 431807994 14295135 complement(1483105..1484643) 1 NC_019908.1 COG0062 Uncharacterized conserved protein; carbohydrate kinase 1484643 14295135 BPP43_07025 Brachyspira pilosicoli P43/6/78 carbohydrate kinase YP_007234892.1 1483105 R 1042417 CDS YP_007234893.1 431807995 14295136 complement(1486430..1486747) 1 NC_019908.1 COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 1486747 14295136 BPP43_07040 Brachyspira pilosicoli P43/6/78 thioredoxin YP_007234893.1 1486430 R 1042417 CDS YP_007234894.1 431807996 14295137 complement(1487172..1488185) 1 NC_019908.1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; FMN-dependent alpha-hydroxy acid dehydrogenase 1488185 14295137 BPP43_07045 Brachyspira pilosicoli P43/6/78 FMN-dependent alpha-hydroxy acid dehydrogenase YP_007234894.1 1487172 R 1042417 CDS YP_007234895.1 431807997 14295138 complement(1488266..1488562) 1 NC_019908.1 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system transporter subunit IIA 1488562 14295138 BPP43_07050 Brachyspira pilosicoli P43/6/78 PTS system transporter subunit IIA YP_007234895.1 1488266 R 1042417 CDS YP_007234896.1 431807998 14295139 complement(1488605..1489936) 1 NC_019908.1 COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; 6-phospho-beta-glucosidase 1489936 14295139 BPP43_07055 Brachyspira pilosicoli P43/6/78 6-phospho-beta-glucosidase YP_007234896.1 1488605 R 1042417 CDS YP_007234897.1 431807999 14295140 complement(1489958..1491343) 1 NC_019908.1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; family 1 glycoside hydrolase 1491343 14295140 BPP43_07060 Brachyspira pilosicoli P43/6/78 family 1 glycoside hydrolase YP_007234897.1 1489958 R 1042417 CDS YP_007234898.1 431808000 14295141 complement(1491367..1492704) 1 NC_019908.1 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC CelB 1492704 14295141 BPP43_07065 Brachyspira pilosicoli P43/6/78 PTS system cellobiose-specific transporter subunit IIC CelB YP_007234898.1 1491367 R 1042417 CDS YP_007234899.1 431808001 14295142 complement(1492739..1494076) 1 NC_019908.1 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC CelB 1494076 14295142 BPP43_07070 Brachyspira pilosicoli P43/6/78 PTS system cellobiose-specific transporter subunit IIC CelB YP_007234899.1 1492739 R 1042417 CDS YP_007234900.1 431808002 14295143 complement(1494125..1495207) 1 NC_019908.1 COG3589 Uncharacterized conserved protein; outer surface protein 1495207 14295143 BPP43_07075 Brachyspira pilosicoli P43/6/78 outer surface protein YP_007234900.1 1494125 R 1042417 CDS YP_007234901.1 431808003 14295144 complement(1495251..1495559) 1 NC_019908.1 COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system cellobiose-specific transporter subunit IIB 1495559 14295144 BPP43_07080 Brachyspira pilosicoli P43/6/78 PTS system cellobiose-specific transporter subunit IIB YP_007234901.1 1495251 R 1042417 CDS YP_007234902.1 431808004 14295145 1495719..1497590 1 NC_019908.1 COG3711 Transcriptional antiterminator; transcriptional antiterminator BglB 1497590 14295145 BPP43_07085 Brachyspira pilosicoli P43/6/78 transcriptional antiterminator BglB YP_007234902.1 1495719 D 1042417 CDS YP_007234903.1 431808005 14295146 1497591..1497857 1 NC_019908.1 COG1925 Phosphotransferase system, HPr-related proteins; PTS system phosphocarrier protein HPr 1497857 14295146 BPP43_07090 Brachyspira pilosicoli P43/6/78 PTS system phosphocarrier protein HPr YP_007234903.1 1497591 D 1042417 CDS YP_007234904.1 431808006 14295147 complement(1497918..1500056) 1 NC_019908.1 COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); polynucleotide phosphorylase/polyadenylase 1500056 14295147 BPP43_07095 Brachyspira pilosicoli P43/6/78 polynucleotide phosphorylase/polyadenylase YP_007234904.1 1497918 R 1042417 CDS YP_007234905.1 431808007 14295148 complement(1500118..1500387) 1 NC_019908.1 COG0184 Ribosomal protein S15P/S13E; 30S ribosomal protein S15 1500387 14295148 BPP43_07100 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S15 YP_007234905.1 1500118 R 1042417 CDS YP_007234906.1 431808008 14295149 complement(1500360..1501289) 1 NC_019908.1 COG0196 FAD synthase; riboflavin biosynthesis protein 1501289 14295149 BPP43_07105 Brachyspira pilosicoli P43/6/78 riboflavin biosynthesis protein YP_007234906.1 1500360 R 1042417 CDS YP_007234907.1 431808009 14295150 complement(1501294..1502241) 1 NC_019908.1 hypothetical protein 1502241 14295150 BPP43_07110 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234907.1 1501294 R 1042417 CDS YP_007234908.1 431808010 14295151 complement(1502290..1502670) 1 NC_019908.1 hypothetical protein 1502670 14295151 BPP43_07115 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234908.1 1502290 R 1042417 CDS YP_007234909.1 431808011 14295152 1502810..1504150 1 NC_019908.1 COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; coenzyme A disulfide reductase 1504150 14295152 BPP43_07120 Brachyspira pilosicoli P43/6/78 coenzyme A disulfide reductase YP_007234909.1 1502810 D 1042417 CDS YP_007234910.1 431808012 14295153 1504240..1504848 1 NC_019908.1 hypothetical protein 1504848 14295153 BPP43_07125 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234910.1 1504240 D 1042417 CDS YP_007234911.1 431808013 14295154 complement(1505291..1506892) 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 1506892 14295154 BPP43_07130 Brachyspira pilosicoli P43/6/78 family 5 extracellular solute-binding protein YP_007234911.1 1505291 R 1042417 CDS YP_007234912.1 431808014 14295155 complement(1507179..1509098) 1 NC_019908.1 COG0326 Molecular chaperone, HSP90 family; heat shock protein 90 1509098 14295155 BPP43_07135 Brachyspira pilosicoli P43/6/78 heat shock protein 90 YP_007234912.1 1507179 R 1042417 CDS YP_007234913.1 431808015 14295156 1510346..1510927 1 NC_019908.1 hypothetical protein 1510927 14295156 BPP43_07150 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234913.1 1510346 D 1042417 CDS YP_007234914.1 431808016 14295157 1510899..1511381 1 NC_019908.1 COG0716 Flavodoxins; flavodoxin 1511381 14295157 BPP43_07155 Brachyspira pilosicoli P43/6/78 flavodoxin YP_007234914.1 1510899 D 1042417 CDS YP_007234915.1 431808017 14295158 complement(1511461..1512513) 1 NC_019908.1 COG0337 3-dehydroquinate synthetase; 3-dehydroquinate synthase 1512513 14295158 BPP43_07160 Brachyspira pilosicoli P43/6/78 3-dehydroquinate synthase YP_007234915.1 1511461 R 1042417 CDS YP_007234916.1 431808018 14295159 1512622..1514958 1 NC_019908.1 hypothetical protein 1514958 14295159 BPP43_07165 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234916.1 1512622 D 1042417 CDS YP_007234917.1 431808019 14295160 complement(1514951..1515358) 1 NC_019908.1 hypothetical protein 1515358 14295160 BPP43_07170 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234917.1 1514951 R 1042417 CDS YP_007234918.1 431808020 14295161 complement(1515455..1517380) 1 NC_019908.1 COG1297 Predicted membrane protein; OPT family oligopeptide transporter 1517380 14295161 BPP43_07175 Brachyspira pilosicoli P43/6/78 OPT family oligopeptide transporter YP_007234918.1 1515455 R 1042417 CDS YP_007234919.1 431808021 14295162 complement(1517440..1518879) 1 NC_019908.1 COG2195 Di- and tripeptidases; Xaa His dipeptidase 1518879 14295162 BPP43_07180 Brachyspira pilosicoli P43/6/78 Xaa His dipeptidase YP_007234919.1 1517440 R 1042417 CDS YP_007234920.1 431808022 14295163 1519487..1520449 1 NC_019908.1 COG0191 Fructose/tagatose bisphosphate aldolase; fructose-bisphosphate aldolase 1520449 14295163 BPP43_07185 Brachyspira pilosicoli P43/6/78 fructose-bisphosphate aldolase YP_007234920.1 1519487 D 1042417 CDS YP_007234921.1 431808023 14295164 1520474..1520566 1 NC_019908.1 hypothetical protein 1520566 14295164 BPP43_07190 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234921.1 1520474 D 1042417 CDS YP_007234922.1 431808024 14295165 1520733..1521641 1 NC_019908.1 COG1912 Uncharacterized conserved protein; hypothetical protein 1521641 14295165 BPP43_07195 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234922.1 1520733 D 1042417 CDS YP_007234923.1 431808025 14295166 1521614..1522414 1 NC_019908.1 COG1573 Uracil-DNA glycosylase; uracil DNA glycosylase 1522414 14295166 BPP43_07200 Brachyspira pilosicoli P43/6/78 uracil DNA glycosylase YP_007234923.1 1521614 D 1042417 CDS YP_007234924.1 431808026 14295167 1522650..1523486 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 1523486 14295167 BPP43_07205 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007234924.1 1522650 D 1042417 CDS YP_007234925.1 431808027 14295168 1523550..1524389 1 NC_019908.1 hypothetical protein 1524389 14295168 BPP43_07210 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234925.1 1523550 D 1042417 CDS YP_007234926.1 431808028 14295169 1524409..1527576 1 NC_019908.1 molybdate metabolism regulator 1527576 14295169 BPP43_07215 Brachyspira pilosicoli P43/6/78 molybdate metabolism regulator YP_007234926.1 1524409 D 1042417 CDS YP_007234927.1 431808029 14295170 complement(1527989..1529374) 1 NC_019908.1 COG0733 Na+-dependent transporters of the SNF family; SNF family sodium-dependent transporter 1529374 14295170 BPP43_07220 Brachyspira pilosicoli P43/6/78 SNF family sodium-dependent transporter YP_007234927.1 1527989 R 1042417 CDS YP_007234928.1 431808030 14295171 1529515..1530783 1 NC_019908.1 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog; RNA polymerase sigma 54 subunit RpoN 1530783 14295171 BPP43_07225 Brachyspira pilosicoli P43/6/78 RNA polymerase sigma 54 subunit RpoN YP_007234928.1 1529515 D 1042417 CDS YP_007234929.1 431808031 14295172 1530803..1531579 1 NC_019908.1 COG1544 Ribosome-associated protein Y (PSrp-1); sigma 54 modulation protein/S30EA ribosomal protein 1531579 14295172 BPP43_07230 Brachyspira pilosicoli P43/6/78 sigma 54 modulation protein/S30EA ribosomal protein YP_007234929.1 1530803 D 1042417 CDS YP_007234930.1 431808032 14295173 1531620..1532084 1 NC_019908.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system fructose subfamily transporter subunit IIC 1532084 14295173 BPP43_07235 Brachyspira pilosicoli P43/6/78 PTS system fructose subfamily transporter subunit IIC YP_007234930.1 1531620 D 1042417 CDS YP_007234931.1 431808033 14295174 1532084..1533034 1 NC_019908.1 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism; Hpr kinase phosphatase 1533034 14295174 BPP43_07240 Brachyspira pilosicoli P43/6/78 Hpr kinase phosphatase YP_007234931.1 1532084 D 1042417 CDS YP_007234932.1 431808034 14295175 1533076..1534137 1 NC_019908.1 COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain; tRNA-(5-methylaminomethyl-2-thiouridylate)- methyltransferase 1534137 14295175 BPP43_07245 Brachyspira pilosicoli P43/6/78 tRNA-(5-methylaminomethyl-2-thiouridylate)- methyltransferase YP_007234932.1 1533076 D 1042417 CDS YP_007234933.1 431808035 14295176 complement(1534617..1535021) 1 NC_019908.1 COG2832 Uncharacterized protein conserved in bacteria; hypothetical protein 1535021 14295176 BPP43_07250 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234933.1 1534617 R 1042417 CDS YP_007234934.1 431808036 14295177 complement(1535128..1535382) 1 NC_019908.1 COG0211 Ribosomal protein L27; 50S ribosomal protein L27 1535382 14295177 BPP43_07255 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L27 YP_007234934.1 1535128 R 1042417 CDS YP_007234935.1 431808037 14295178 complement(1535372..1535728) 1 NC_019908.1 COG2868 Predicted ribosomal protein; hypothetical protein 1535728 14295178 BPP43_07260 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234935.1 1535372 R 1042417 CDS YP_007234936.1 431808038 14295179 complement(1535919..1536050) 1 NC_019908.1 COG0261 Ribosomal protein L21; 50S ribosomal protein L21 1536050 14295179 BPP43_07265 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L21 YP_007234936.1 1535919 R 1042417 CDS YP_007234937.1 431808039 14295180 complement(1536138..1537091) 1 NC_019908.1 COG0760 Parvulin-like peptidyl-prolyl isomerase; PpiC-type peptidyl-prolyl cis-trans isomerase 1537091 14295180 BPP43_07270 Brachyspira pilosicoli P43/6/78 PpiC-type peptidyl-prolyl cis-trans isomerase YP_007234937.1 1536138 R 1042417 CDS YP_007234938.1 431808040 14295181 complement(1537249..1537896) 1 NC_019908.1 hypothetical protein 1537896 14295181 BPP43_07275 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234938.1 1537249 R 1042417 CDS YP_007234939.1 431808041 14295182 1538140..1539021 1 NC_019908.1 COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); fumarylacetoacetate (FAA) hydrolase family protein 1539021 14295182 BPP43_07280 Brachyspira pilosicoli P43/6/78 fumarylacetoacetate (FAA) hydrolase family protein YP_007234939.1 1538140 D 1042417 CDS YP_007234940.1 431808042 14295183 complement(1539023..1539529) 1 NC_019908.1 COG1435 Thymidine kinase; thymidine kinase 1539529 14295183 BPP43_07285 Brachyspira pilosicoli P43/6/78 thymidine kinase YP_007234940.1 1539023 R 1042417 CDS YP_007234941.1 431808043 14295184 1539793..1541463 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1541463 14295184 BPP43_07290 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234941.1 1539793 D 1042417 CDS YP_007234942.1 431808044 14295185 1541525..1542202 1 NC_019908.1 COG3544 Uncharacterized protein conserved in bacteria; hypothetical protein 1542202 14295185 BPP43_07295 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234942.1 1541525 D 1042417 CDS YP_007234943.1 431808045 14295186 1542362..1543402 1 NC_019908.1 COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; myristoyl-acyl carrier protein (ACP)-dependent acyltransferase 1543402 14295186 BPP43_07300 Brachyspira pilosicoli P43/6/78 myristoyl-acyl carrier protein (ACP)-dependent acyltransferase YP_007234943.1 1542362 D 1042417 CDS YP_007234944.1 431808046 14295187 complement(1544297..1547449) 1 NC_019908.1 COG0841 Cation/multidrug efflux pump; acriflavin resistance protein 1547449 14295187 BPP43_07315 Brachyspira pilosicoli P43/6/78 acriflavin resistance protein YP_007234944.1 1544297 R 1042417 CDS YP_007234945.1 431808047 14295188 complement(1549082..1549567) 1 NC_019908.1 COG0691 tmRNA-binding protein; ssrA-binding protein 1549567 14295188 BPP43_07330 Brachyspira pilosicoli P43/6/78 ssrA-binding protein YP_007234945.1 1549082 R 1042417 CDS YP_007234946.1 431808048 14295189 1550842..1551237 1 NC_019908.1 COG1869 ABC-type ribose transport system, auxiliary component; D-ribose pyranase 1551237 14295189 BPP43_07345 Brachyspira pilosicoli P43/6/78 D-ribose pyranase YP_007234946.1 1550842 D 1042417 CDS YP_007234947.1 431808049 14295190 1551259..1552746 1 NC_019908.1 COG1129 ABC-type sugar transport system, ATPase component; monosaccharide-transporting ATPase 1552746 14295190 BPP43_07350 Brachyspira pilosicoli P43/6/78 monosaccharide-transporting ATPase YP_007234947.1 1551259 D 1042417 CDS YP_007234948.1 431808050 14295191 1552743..1553678 1 NC_019908.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; ribose ABC transporter permease 1553678 14295191 BPP43_07355 Brachyspira pilosicoli P43/6/78 ribose ABC transporter permease YP_007234948.1 1552743 D 1042417 CDS YP_007234949.1 431808051 14295192 1553721..1554614 1 NC_019908.1 COG1879 ABC-type sugar transport system, periplasmic component; periplasmic binding protein/LacI transcriptional regulator 1554614 14295192 BPP43_07360 Brachyspira pilosicoli P43/6/78 periplasmic binding protein/LacI transcriptional regulator YP_007234949.1 1553721 D 1042417 CDS YP_007234950.1 431808052 14295193 1554679..1555548 1 NC_019908.1 COG0524 Sugar kinases, ribokinase family; ribokinase 1555548 14295193 BPP43_07365 Brachyspira pilosicoli P43/6/78 ribokinase YP_007234950.1 1554679 D 1042417 CDS YP_007234951.1 431808053 14295194 1555844..1555978 1 NC_019908.1 hypothetical protein 1555978 14295194 BPP43_07370 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234951.1 1555844 D 1042417 CDS YP_007234952.1 431808054 14295195 1556030..1556278 1 NC_019908.1 hypothetical protein 1556278 14295195 BPP43_07375 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234952.1 1556030 D 1042417 CDS YP_007234953.1 431808055 14295196 1556332..1556814 1 NC_019908.1 hypothetical protein 1556814 14295196 BPP43_07380 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234953.1 1556332 D 1042417 CDS YP_007234954.1 431808056 14295197 1557009..1558538 1 NC_019908.1 hypothetical protein 1558538 14295197 BPP43_07385 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234954.1 1557009 D 1042417 CDS YP_007234955.1 431808057 14294494 1560980..1561732 1 NC_019908.1 hypothetical protein 1561732 14294494 BPP43_07390 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234955.1 1560980 D 1042417 CDS YP_007234956.1 431808058 14295199 1563798..1563881 1 NC_019908.1 hypothetical protein 1563881 14295199 BPP43_07405 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234956.1 1563798 D 1042417 CDS YP_007234957.1 431808059 14295200 1563881..1564258 1 NC_019908.1 COG0727 Predicted Fe-S-cluster oxidoreductase; hypothetical protein 1564258 14295200 BPP43_07410 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234957.1 1563881 D 1042417 CDS YP_007234958.1 431808060 14295201 complement(1565813..1566136) 1 NC_019908.1 hypothetical protein 1566136 14295201 BPP43_07425 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234958.1 1565813 R 1042417 CDS YP_007234959.1 431808061 14295202 complement(1566133..1566609) 1 NC_019908.1 COG1406 Predicted inhibitor of MCP methylation, homolog of CheC; chemotaxis protein CheX 1566609 14295202 BPP43_07430 Brachyspira pilosicoli P43/6/78 chemotaxis protein CheX YP_007234959.1 1566133 R 1042417 CDS YP_007234960.1 431808062 14295203 1566847..1567875 1 NC_019908.1 COG2008 Threonine aldolase; aromatic amino acid beta-eliminating lyase/threonine aldolase 1567875 14295203 BPP43_07435 Brachyspira pilosicoli P43/6/78 aromatic amino acid beta-eliminating lyase/threonine aldolase YP_007234960.1 1566847 D 1042417 CDS YP_007234961.1 431808063 14295204 1568202..1569245 1 NC_019908.1 COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; 3-deoxy-7-phosphoheptulonate synthase 1569245 14295204 BPP43_07440 Brachyspira pilosicoli P43/6/78 3-deoxy-7-phosphoheptulonate synthase YP_007234961.1 1568202 D 1042417 CDS YP_007234962.1 431808064 14295205 complement(1569804..1574006) 1 NC_019908.1 COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-directed RNA polymerase subunit beta' 1574006 14295205 BPP43_07445 Brachyspira pilosicoli P43/6/78 DNA-directed RNA polymerase subunit beta' YP_007234962.1 1569804 R 1042417 CDS YP_007234963.1 431808065 14295206 complement(1574021..1577542) 1 NC_019908.1 COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA directed RNA polymerase subunit beta 1577542 14295206 BPP43_07450 Brachyspira pilosicoli P43/6/78 DNA directed RNA polymerase subunit beta YP_007234963.1 1574021 R 1042417 CDS YP_007234964.1 431808066 14295207 complement(1577672..1578061) 1 NC_019908.1 COG0222 Ribosomal protein L7/L12; 50S ribosomal protein L7/L12 1578061 14295207 BPP43_07455 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L7/L12 YP_007234964.1 1577672 R 1042417 CDS YP_007234965.1 431808067 14295208 complement(1578119..1578643) 1 NC_019908.1 COG0244 Ribosomal protein L10; 50S ribosomal protein L10 1578643 14295208 BPP43_07460 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L10 YP_007234965.1 1578119 R 1042417 CDS YP_007234966.1 431808068 14295209 complement(1578745..1579446) 1 NC_019908.1 COG0081 Ribosomal protein L1; 50S ribosomal protein L1 1579446 14295209 BPP43_07465 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L1 YP_007234966.1 1578745 R 1042417 CDS YP_007234967.1 431808069 14295210 complement(1579520..1579942) 1 NC_019908.1 COG0080 Ribosomal protein L11; 50S ribosomal protein L11 1579942 14295210 BPP43_07470 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L11 YP_007234967.1 1579520 R 1042417 CDS YP_007234968.1 431808070 14295211 complement(1580547..1580867) 1 NC_019908.1 COG0690 Preprotein translocase subunit SecE; preprotein translocase subunit SecE 1580867 14295211 BPP43_07485 Brachyspira pilosicoli P43/6/78 preprotein translocase subunit SecE YP_007234968.1 1580547 R 1042417 CDS YP_007234969.1 431808071 14295213 complement(1580996..1581172) 1 NC_019908.1 COG0267 Ribosomal protein L33; 50S ribosomal protein L33 1581172 14295213 BPP43_07490 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L33 YP_007234969.1 1580996 R 1042417 CDS YP_007234970.1 431808072 14295214 complement(1583538..1584347) 1 NC_019908.1 COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; phosphomethylpyrimidine kinase 1584347 14295214 BPP43_07495 Brachyspira pilosicoli P43/6/78 phosphomethylpyrimidine kinase YP_007234970.1 1583538 R 1042417 CDS YP_007234971.1 431808073 14295215 complement(1584366..1585076) 1 NC_019908.1 COG0784 FOG: CheY-like receiver; two component transcriptional regulator winged helix family protein 1585076 14295215 BPP43_07500 Brachyspira pilosicoli P43/6/78 two component transcriptional regulator winged helix family protein YP_007234971.1 1584366 R 1042417 CDS YP_007234972.1 431808074 14295216 1585210..1586178 1 NC_019908.1 COG3191 L-aminopeptidase/D-esterase; esterase 1586178 14295216 BPP43_07505 Brachyspira pilosicoli P43/6/78 esterase YP_007234972.1 1585210 D 1042417 CDS YP_007234973.1 431808075 14295217 1586165..1586752 1 NC_019908.1 COG0194 Guanylate kinase; hypothetical protein 1586752 14295217 BPP43_07510 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234973.1 1586165 D 1042417 CDS YP_007234974.1 431808076 14295218 complement(1586798..1587427) 1 NC_019908.1 hypothetical protein 1587427 14295218 BPP43_07515 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234974.1 1586798 R 1042417 CDS YP_007234975.1 431808077 14295219 1587633..1587983 1 NC_019908.1 COG1633 Uncharacterized conserved protein; hypothetical protein 1587983 14295219 BPP43_07520 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234975.1 1587633 D 1042417 CDS YP_007234976.1 431808078 14295220 1588030..1588839 1 NC_019908.1 COG1659 Uncharacterized protein, linocin/CFP29 homolog; linocin M18 bacteriocin protein 1588839 14295220 BPP43_07525 Brachyspira pilosicoli P43/6/78 linocin M18 bacteriocin protein YP_007234976.1 1588030 D 1042417 CDS YP_007234977.1 431808079 14295221 1588963..1589739 1 NC_019908.1 COG1434 Uncharacterized conserved protein; hypothetical protein 1589739 14295221 BPP43_07530 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234977.1 1588963 D 1042417 CDS YP_007234978.1 431808080 14295222 1589823..1590791 1 NC_019908.1 COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; 3-oxoacyl-(acyl-carrier-protein) synthase III 1590791 14295222 BPP43_07535 Brachyspira pilosicoli P43/6/78 3-oxoacyl-(acyl-carrier-protein) synthase III YP_007234978.1 1589823 D 1042417 CDS YP_007234979.1 431808081 14295223 complement(1590859..1591785) 1 NC_019908.1 glycosyltransferase family 8 protein 1591785 14295223 BPP43_07540 Brachyspira pilosicoli P43/6/78 glycosyltransferase family 8 protein YP_007234979.1 1590859 R 1042417 CDS YP_007234980.1 431808082 14295224 1592775..1593950 1 NC_019908.1 COG0183 Acetyl-CoA acetyltransferase; Yqi jprotein 1593950 14295224 BPP43_07555 Brachyspira pilosicoli P43/6/78 Yqi jprotein YP_007234980.1 1592775 D 1042417 CDS YP_007234981.1 431808083 14295225 complement(1595526..1597208) 1 NC_019908.1 hypothetical protein 1597208 14295225 BPP43_07570 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234981.1 1595526 R 1042417 CDS YP_007234982.1 431808084 14295226 complement(1597391..1597585) 1 NC_019908.1 hypothetical protein 1597585 14295226 BPP43_07575 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234982.1 1597391 R 1042417 CDS YP_007234983.1 431808085 14295227 complement(1597949..1599271) 1 NC_019908.1 COG0534 Na+-driven multidrug efflux pump; MATE efflux family protein 1599271 14295227 BPP43_07580 Brachyspira pilosicoli P43/6/78 MATE efflux family protein YP_007234983.1 1597949 R 1042417 CDS YP_007234984.1 431808086 14295228 complement(1599399..1600397) 1 NC_019908.1 COG1089 GDP-D-mannose dehydratase; GDP-D-mannose dehydratase 1600397 14295228 BPP43_07585 Brachyspira pilosicoli P43/6/78 GDP-D-mannose dehydratase YP_007234984.1 1599399 R 1042417 CDS YP_007234985.1 431808087 14295229 complement(1600416..1601348) 1 NC_019908.1 COG0451 Nucleoside-diphosphate-sugar epimerases; GDP-fucose synthetase 1601348 14295229 BPP43_07590 Brachyspira pilosicoli P43/6/78 GDP-fucose synthetase YP_007234985.1 1600416 R 1042417 CDS YP_007234986.1 431808088 14295230 complement(1601541..1602320) 1 NC_019908.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; dolichyl-phosphate beta-D-mannosyltransferase 1602320 14295230 BPP43_07595 Brachyspira pilosicoli P43/6/78 dolichyl-phosphate beta-D-mannosyltransferase YP_007234986.1 1601541 R 1042417 CDS YP_007234987.1 431808089 14295231 complement(1602324..1602950) 1 NC_019908.1 hypothetical protein 1602950 14295231 BPP43_07600 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234987.1 1602324 R 1042417 CDS YP_007234988.1 431808090 14295232 complement(1602956..1603621) 1 NC_019908.1 hypothetical protein 1603621 14295232 BPP43_07605 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234988.1 1602956 R 1042417 CDS YP_007234989.1 431808091 14295233 complement(1603621..1605012) 1 NC_019908.1 hypothetical protein 1605012 14295233 BPP43_07610 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234989.1 1603621 R 1042417 CDS YP_007234990.1 431808092 14295234 complement(1605002..1605178) 1 NC_019908.1 hypothetical protein 1605178 14295234 BPP43_07615 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234990.1 1605002 R 1042417 CDS YP_007234991.1 431808093 14295235 1605363..1605788 1 NC_019908.1 COG1862 Preprotein translocase subunit YajC; preprotein translocase subunit YajC 1605788 14295235 BPP43_07620 Brachyspira pilosicoli P43/6/78 preprotein translocase subunit YajC YP_007234991.1 1605363 D 1042417 CDS YP_007234992.1 431808094 14295236 1605824..1607335 1 NC_019908.1 COG0342 Preprotein translocase subunit SecD; preprotein translocase subunit SecD 1607335 14295236 BPP43_07625 Brachyspira pilosicoli P43/6/78 preprotein translocase subunit SecD YP_007234992.1 1605824 D 1042417 CDS YP_007234993.1 431808095 14295237 1607356..1608300 1 NC_019908.1 COG0341 Preprotein translocase subunit SecF; preprotein translocase 1608300 14295237 BPP43_07630 Brachyspira pilosicoli P43/6/78 preprotein translocase YP_007234993.1 1607356 D 1042417 CDS YP_007234994.1 431808096 14295238 complement(1609561..1610319) 1 NC_019908.1 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; glucosamine-6-phosphate deaminase 1610319 14295238 BPP43_07645 Brachyspira pilosicoli P43/6/78 glucosamine-6-phosphate deaminase YP_007234994.1 1609561 R 1042417 CDS YP_007234995.1 431808097 14295239 1610514..1611167 1 NC_019908.1 COG0637 Predicted phosphatase/phosphohexomutase; haloacid dehalogenase 1611167 14295239 BPP43_07650 Brachyspira pilosicoli P43/6/78 haloacid dehalogenase YP_007234995.1 1610514 D 1042417 CDS YP_007234996.1 431808098 14295240 complement(1611241..1612680) 1 NC_019908.1 COG0112 Glycine/serine hydroxymethyltransferase; glycine hydroxymethyltransferase 1612680 14295240 BPP43_07655 Brachyspira pilosicoli P43/6/78 glycine hydroxymethyltransferase YP_007234996.1 1611241 R 1042417 CDS YP_007234997.1 431808099 14295241 1612898..1613959 1 NC_019908.1 hypothetical protein 1613959 14295241 BPP43_07660 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234997.1 1612898 D 1042417 CDS YP_007234998.1 431808100 14295242 complement(1614039..1614680) 1 NC_019908.1 hypothetical protein 1614680 14295242 BPP43_07665 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007234998.1 1614039 R 1042417 CDS YP_007234999.1 431808101 14295243 complement(1614876..1615430) 1 NC_019908.1 COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; pyruvate ferredoxin/flavodoxin oxidoreductase 1615430 14295243 BPP43_07670 Brachyspira pilosicoli P43/6/78 pyruvate ferredoxin/flavodoxin oxidoreductase YP_007234999.1 1614876 R 1042417 CDS YP_007235000.1 431808102 14295244 complement(1615444..1616178) 1 NC_019908.1 COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; thiamine pyrophosphate domain-containing TPP-binding protein 1616178 14295244 BPP43_07675 Brachyspira pilosicoli P43/6/78 thiamine pyrophosphate domain-containing TPP-binding protein YP_007235000.1 1615444 R 1042417 CDS YP_007235001.1 431808103 14295245 complement(1616175..1617230) 1 NC_019908.1 COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; 2-ketoisovalerate ferredoxin reductase 1617230 14295245 BPP43_07680 Brachyspira pilosicoli P43/6/78 2-ketoisovalerate ferredoxin reductase YP_007235001.1 1616175 R 1042417 CDS YP_007235002.1 431808104 14295246 complement(1617230..1617466) 1 NC_019908.1 COG1146 Ferredoxin; ferredoxin 1617466 14295246 BPP43_07685 Brachyspira pilosicoli P43/6/78 ferredoxin YP_007235002.1 1617230 R 1042417 CDS YP_007235003.1 431808105 14295247 complement(1617658..1619109) 1 NC_019908.1 COG0647 Predicted sugar phosphatases of the HAD superfamily; hypothetical protein 1619109 14295247 BPP43_07690 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235003.1 1617658 R 1042417 CDS YP_007235004.1 431808106 14295248 complement(1619205..1619396) 1 NC_019908.1 hypothetical protein 1619396 14295248 BPP43_07695 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235004.1 1619205 R 1042417 CDS YP_007235005.1 431808107 14295249 complement(1619489..1620247) 1 NC_019908.1 COG1126 ABC-type polar amino acid transport system, ATPase component; polar amino acid ABC transporter ATPase 1620247 14295249 BPP43_07700 Brachyspira pilosicoli P43/6/78 polar amino acid ABC transporter ATPase YP_007235005.1 1619489 R 1042417 CDS YP_007235006.1 431808108 14295250 complement(1620231..1620926) 1 NC_019908.1 COG0765 ABC-type amino acid transport system, permease component; His/Glu/Gln/Arg/opine family amino acid ABC transporter permease 1620926 14295250 BPP43_07705 Brachyspira pilosicoli P43/6/78 His/Glu/Gln/Arg/opine family amino acid ABC transporter permease YP_007235006.1 1620231 R 1042417 CDS YP_007235007.1 431808109 14295251 complement(1621070..1621693) 1 NC_019908.1 hypothetical protein 1621693 14295251 BPP43_07710 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235007.1 1621070 R 1042417 CDS YP_007235008.1 431808110 14295252 complement(1621942..1625679) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1625679 14295252 BPP43_07715 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235008.1 1621942 R 1042417 CDS YP_007235009.1 431808111 14295253 1625959..1626540 1 NC_019908.1 hypothetical protein 1626540 14295253 BPP43_07720 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235009.1 1625959 D 1042417 CDS YP_007235010.1 431808112 14295254 complement(1626598..1627206) 1 NC_019908.1 hypothetical protein 1627206 14295254 BPP43_07725 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235010.1 1626598 R 1042417 CDS YP_007235011.1 431808113 14295255 complement(1627234..1627491) 1 NC_019908.1 hypothetical protein 1627491 14295255 BPP43_07730 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235011.1 1627234 R 1042417 CDS YP_007235012.1 431808114 14295256 complement(1627524..1628057) 1 NC_019908.1 hypothetical protein 1628057 14295256 BPP43_07735 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235012.1 1627524 R 1042417 CDS YP_007235013.1 431808115 14295257 complement(1628625..1629194) 1 NC_019908.1 hypothetical protein 1629194 14295257 BPP43_07740 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235013.1 1628625 R 1042417 CDS YP_007235014.1 431808116 14295258 complement(1629395..1629970) 1 NC_019908.1 hypothetical protein 1629970 14295258 BPP43_07745 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235014.1 1629395 R 1042417 CDS YP_007235015.1 431808117 14295259 1630361..1631362 1 NC_019908.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; quinone reductase 1631362 14295259 BPP43_07750 Brachyspira pilosicoli P43/6/78 quinone reductase YP_007235015.1 1630361 D 1042417 CDS YP_007235016.1 431808118 14295260 complement(1631703..1632068) 1 NC_019908.1 hypothetical protein 1632068 14295260 BPP43_07755 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235016.1 1631703 R 1042417 CDS YP_007235017.1 431808119 14295261 complement(1634941..1636149) 1 NC_019908.1 COG1219 ATP-dependent protease Clp, ATPase subunit; ATP-dependent Clp protease ATP-binding subunit ClpX 1636149 14295261 BPP43_07770 Brachyspira pilosicoli P43/6/78 ATP-dependent Clp protease ATP-binding subunit ClpX YP_007235017.1 1634941 R 1042417 CDS YP_007235018.1 431808120 14295262 1636371..1637942 1 NC_019908.1 hypothetical protein 1637942 14295262 BPP43_07775 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235018.1 1636371 D 1042417 CDS YP_007235019.1 431808121 14295263 complement(1639505..1640098) 1 NC_019908.1 COG1360 Flagellar motor protein; hypothetical protein 1640098 14295263 BPP43_07790 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235019.1 1639505 R 1042417 CDS YP_007235020.1 431808122 14295264 1640302..1641324 1 NC_019908.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; response regulatory protein 1641324 14295264 BPP43_07795 Brachyspira pilosicoli P43/6/78 response regulatory protein YP_007235020.1 1640302 D 1042417 CDS YP_007235021.1 431808123 14295265 1641355..1641945 1 NC_019908.1 COG0009 Putative translation factor (SUA5); Sua5/YciO/YrdC/YwlC family protein 1641945 14295265 BPP43_07800 Brachyspira pilosicoli P43/6/78 Sua5/YciO/YrdC/YwlC family protein YP_007235021.1 1641355 D 1042417 CDS YP_007235022.1 431808124 14295266 1642736..1644112 1 NC_019908.1 COG0750 Predicted membrane-associated Zn-dependent proteases 1; membrane-associated zinc metalloprotease 1644112 14295266 BPP43_07805 Brachyspira pilosicoli P43/6/78 membrane-associated zinc metalloprotease YP_007235022.1 1642736 D 1042417 CDS YP_007235023.1 431808125 14295267 complement(1644202..1644588) 1 NC_019908.1 COG0346 Lactoylglutathione lyase and related lyases; glyoxalase family protein 1644588 14295267 BPP43_07810 Brachyspira pilosicoli P43/6/78 glyoxalase family protein YP_007235023.1 1644202 R 1042417 CDS YP_007235024.1 431808126 14295268 complement(1644608..1645759) 1 NC_019908.1 COG2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; VWA containing CoxE family protein 1645759 14295268 BPP43_07815 Brachyspira pilosicoli P43/6/78 VWA containing CoxE family protein YP_007235024.1 1644608 R 1042417 CDS YP_007235025.1 431808127 14295269 complement(1646376..1647470) 1 NC_019908.1 hypothetical protein 1647470 14295269 BPP43_07820 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235025.1 1646376 R 1042417 CDS YP_007235026.1 431808128 14295271 complement(1647707..1648300) 1 NC_019908.1 COG1437 Adenylate cyclase, class 2 (thermophilic); adenylate cyclase 1648300 14295271 BPP43_07825 Brachyspira pilosicoli P43/6/78 adenylate cyclase YP_007235026.1 1647707 R 1042417 CDS YP_007235027.1 431808129 14295272 complement(1648325..1649488) 1 NC_019908.1 COG5505 Predicted integral membrane protein; hypothetical protein 1649488 14295272 BPP43_07830 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235027.1 1648325 R 1042417 CDS YP_007235028.1 431808130 14295273 1649802..1651565 1 NC_019908.1 COG0173 Aspartyl-tRNA synthetase; aspartyl-tRNA synthetase 1651565 14295273 BPP43_07835 Brachyspira pilosicoli P43/6/78 aspartyl-tRNA synthetase YP_007235028.1 1649802 D 1042417 CDS YP_007235029.1 431808131 14295274 1651762..1653549 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1653549 14295274 BPP43_07840 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235029.1 1651762 D 1042417 CDS YP_007235030.1 431808132 14295275 1653907..1655316 1 NC_019908.1 COG1115 Na+/alanine symporter; sodium/alanine symporter 1655316 14295275 BPP43_07845 Brachyspira pilosicoli P43/6/78 sodium/alanine symporter YP_007235030.1 1653907 D 1042417 CDS YP_007235031.1 431808133 14295276 complement(1655381..1656490) 1 NC_019908.1 hypothetical protein 1656490 14295276 BPP43_07850 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235031.1 1655381 R 1042417 CDS YP_007235032.1 431808134 14295277 complement(1656710..1656823) 1 NC_019908.1 hypothetical protein 1656823 14295277 BPP43_07855 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235032.1 1656710 R 1042417 CDS YP_007235033.1 431808135 14295278 complement(1657095..1658072) 1 NC_019908.1 COG1783 Phage terminase large subunit; phage terminase large subunit 1658072 14295278 BPP43_07860 Brachyspira pilosicoli P43/6/78 phage terminase large subunit YP_007235033.1 1657095 R 1042417 CDS YP_007235034.1 431808136 14295279 complement(1658283..1658654) 1 NC_019908.1 hypothetical protein 1658654 14295279 BPP43_07865 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235034.1 1658283 R 1042417 CDS YP_007235035.1 431808137 14295280 1658876..1659634 1 NC_019908.1 hypothetical protein 1659634 14295280 BPP43_07870 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235035.1 1658876 D 1042417 CDS YP_007235036.1 431808138 14295281 1659763..1660110 1 NC_019908.1 hypothetical protein 1660110 14295281 BPP43_07875 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235036.1 1659763 D 1042417 CDS YP_007235037.1 431808139 14295282 complement(1660256..1661353) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 1661353 14295282 BPP43_07880 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007235037.1 1660256 R 1042417 CDS YP_007235038.1 431808140 14295283 1661766..1662725 1 NC_019908.1 COG2958 Uncharacterized protein conserved in bacteria; hypothetical protein 1662725 14295283 BPP43_07885 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235038.1 1661766 D 1042417 CDS YP_007235039.1 431808141 14295284 complement(1662797..1663375) 1 NC_019908.1 hypothetical protein 1663375 14295284 BPP43_07890 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235039.1 1662797 R 1042417 CDS YP_007235040.1 431808142 14295285 complement(1663404..1664273) 1 NC_019908.1 hypothetical protein 1664273 14295285 BPP43_07895 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235040.1 1663404 R 1042417 CDS YP_007235041.1 431808143 14295286 complement(1664457..1665440) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; hypothetical protein 1665440 14295286 BPP43_07900 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235041.1 1664457 R 1042417 CDS YP_007235042.1 431808144 14295287 complement(1665715..1666284) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 1666284 14295287 BPP43_07905 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007235042.1 1665715 R 1042417 CDS YP_007235043.1 431808145 14295288 1666460..1666882 1 NC_019908.1 hypothetical protein 1666882 14295288 BPP43_07910 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235043.1 1666460 D 1042417 CDS YP_007235044.1 431808146 14295289 1667148..1669313 1 NC_019908.1 COG0826 Collagenase and related proteases; U32 family peptidase 1669313 14295289 BPP43_07915 Brachyspira pilosicoli P43/6/78 U32 family peptidase YP_007235044.1 1667148 D 1042417 CDS YP_007235045.1 431808147 14295290 complement(1669365..1670705) 1 NC_019908.1 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 1670705 14295290 BPP43_07920 Brachyspira pilosicoli P43/6/78 PTS system cellobiose-specific transporter subunit IIC YP_007235045.1 1669365 R 1042417 CDS YP_007235046.1 431808148 14295291 1670881..1672305 1 NC_019908.1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; family 1 glycoside hydrolase 1672305 14295291 BPP43_07925 Brachyspira pilosicoli P43/6/78 family 1 glycoside hydrolase YP_007235046.1 1670881 D 1042417 CDS YP_007235047.1 431808149 14295292 complement(1672406..1673698) 1 NC_019908.1 COG1301 Na+/H+-dicarboxylate symporters; Na/H dicarboxylate symporters putative 1673698 14295292 BPP43_07930 Brachyspira pilosicoli P43/6/78 Na/H dicarboxylate symporters putative YP_007235047.1 1672406 R 1042417 CDS YP_007235048.1 431808150 14295293 complement(1673812..1674282) 1 NC_019908.1 COG0054 Riboflavin synthase beta-chain; riboflavin synthase subunit beta 1674282 14295293 BPP43_07935 Brachyspira pilosicoli P43/6/78 riboflavin synthase subunit beta YP_007235048.1 1673812 R 1042417 CDS YP_007235049.1 431808151 14295294 complement(1675987..1676628) 1 NC_019908.1 COG0307 Riboflavin synthase alpha chain; riboflavin synthase subunit alpha 1676628 14295294 BPP43_07950 Brachyspira pilosicoli P43/6/78 riboflavin synthase subunit alpha YP_007235049.1 1675987 R 1042417 CDS YP_007235050.1 431808152 14295295 complement(1678188..1678823) 1 NC_019908.1 COG1386 Predicted transcriptional regulator containing the HTH domain; segregation and condesation protein B 1678823 14295295 BPP43_07965 Brachyspira pilosicoli P43/6/78 segregation and condesation protein B YP_007235050.1 1678188 R 1042417 CDS YP_007235051.1 431808153 14295296 complement(1678916..1679410) 1 NC_019908.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; nudix hydrolase 1679410 14295296 BPP43_07970 Brachyspira pilosicoli P43/6/78 nudix hydrolase YP_007235051.1 1678916 R 1042417 CDS YP_007235052.1 431808154 14295297 complement(1679429..1680889) 1 NC_019908.1 COG1032 Fe-S oxidoreductase; Fe-S-oxidoreductase 1680889 14295297 BPP43_07975 Brachyspira pilosicoli P43/6/78 Fe-S-oxidoreductase YP_007235052.1 1679429 R 1042417 CDS YP_007235053.1 431808155 14295298 complement(1680907..1681347) 1 NC_019908.1 hypothetical protein 1681347 14295298 BPP43_07980 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235053.1 1680907 R 1042417 CDS YP_007235054.1 431808156 14295299 complement(1681391..1681681) 1 NC_019908.1 hypothetical protein 1681681 14295299 BPP43_07985 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235054.1 1681391 R 1042417 CDS YP_007235055.1 431808157 14295300 1681845..1682480 1 NC_019908.1 hypothetical protein 1682480 14295300 BPP43_07990 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235055.1 1681845 D 1042417 CDS YP_007235056.1 431808158 14295301 complement(1682785..1683225) 1 NC_019908.1 COG1846 Transcriptional regulators; transcriptional regulator MarR 1683225 14295301 BPP43_07995 Brachyspira pilosicoli P43/6/78 transcriptional regulator MarR YP_007235056.1 1682785 R 1042417 CDS YP_007235057.1 431808159 14295302 complement(1683237..1684625) 1 NC_019908.1 COG0733 Na+-dependent transporters of the SNF family; SNF family sodium-dependent transporter 1684625 14295302 BPP43_08000 Brachyspira pilosicoli P43/6/78 SNF family sodium-dependent transporter YP_007235057.1 1683237 R 1042417 CDS YP_007235058.1 431808160 14295303 1685679..1685966 1 NC_019908.1 carbon nitrogen hydrolase family protein 1685966 14295303 BPP43_08015 Brachyspira pilosicoli P43/6/78 carbon nitrogen hydrolase family protein YP_007235058.1 1685679 D 1042417 CDS YP_007235059.1 431808161 14295304 1685944..1686477 1 NC_019908.1 COG0388 Predicted amidohydrolase; carbon nitrogen hydrolase family protein 1686477 14295304 BPP43_08020 Brachyspira pilosicoli P43/6/78 carbon nitrogen hydrolase family protein YP_007235059.1 1685944 D 1042417 CDS YP_007235060.1 431808162 14295305 complement(1686474..1686947) 1 NC_019908.1 hypothetical protein 1686947 14295305 BPP43_08025 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235060.1 1686474 R 1042417 CDS YP_007235061.1 431808163 14295306 complement(1686965..1688083) 1 NC_019908.1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; aminotransferase 1688083 14295306 BPP43_08030 Brachyspira pilosicoli P43/6/78 aminotransferase YP_007235061.1 1686965 R 1042417 CDS YP_007235062.1 431808164 14295307 1688226..1688558 1 NC_019908.1 hypothetical protein 1688558 14295307 BPP43_08035 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235062.1 1688226 D 1042417 CDS YP_007235063.1 431808165 14295308 1688626..1688751 1 NC_019908.1 hypothetical protein 1688751 14295308 BPP43_08040 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235063.1 1688626 D 1042417 CDS YP_007235064.1 431808166 14295309 1688760..1689191 1 NC_019908.1 hypothetical protein 1689191 14295309 BPP43_08045 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235064.1 1688760 D 1042417 CDS YP_007235065.1 431808167 14295310 1689271..1689555 1 NC_019908.1 COG4980 Gas vesicle protein; hypothetical protein 1689555 14295310 BPP43_08050 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235065.1 1689271 D 1042417 CDS YP_007235066.1 431808168 14295311 1689582..1689974 1 NC_019908.1 hypothetical protein 1689974 14295311 BPP43_08055 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235066.1 1689582 D 1042417 CDS YP_007235067.1 431808169 14295312 1689997..1691043 1 NC_019908.1 hypothetical protein 1691043 14295312 BPP43_08060 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235067.1 1689997 D 1042417 CDS YP_007235068.1 431808170 14295313 1691054..1691962 1 NC_019908.1 hypothetical protein 1691962 14295313 BPP43_08065 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235068.1 1691054 D 1042417 CDS YP_007235069.1 431808171 14295314 complement(1692421..1693158) 1 NC_019908.1 COG1994 Zn-dependent proteases; peptidase M50 1693158 14295314 BPP43_08070 Brachyspira pilosicoli P43/6/78 peptidase M50 YP_007235069.1 1692421 R 1042417 CDS YP_007235070.1 431808172 14295315 complement(1693261..1694001) 1 NC_019908.1 COG0336 tRNA-(guanine-N1)-methyltransferase; tRNA (guanine-N1-)-methyltransferase 1694001 14295315 BPP43_08075 Brachyspira pilosicoli P43/6/78 tRNA (guanine-N1-)-methyltransferase YP_007235070.1 1693261 R 1042417 CDS YP_007235071.1 431808173 14295316 1694123..1695148 1 NC_019908.1 hypothetical protein 1695148 14295316 BPP43_08080 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235071.1 1694123 D 1042417 CDS YP_007235072.1 431808174 14295317 1695141..1696442 1 NC_019908.1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; Holliday junction resolvase-like ATPase 1696442 14295317 BPP43_08085 Brachyspira pilosicoli P43/6/78 Holliday junction resolvase-like ATPase YP_007235072.1 1695141 D 1042417 CDS YP_007235073.1 431808175 14295318 1696951..1697442 1 NC_019908.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 1697442 14295318 BPP43_08090 Brachyspira pilosicoli P43/6/78 acetyltransferase YP_007235073.1 1696951 D 1042417 CDS YP_007235074.1 431808176 14295319 complement(1697445..1697540) 1 NC_019908.1 hypothetical protein 1697540 14295319 BPP43_08095 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235074.1 1697445 R 1042417 CDS YP_007235075.1 431808177 14295320 1698312..1698869 1 NC_019908.1 COG0209 Ribonucleotide reductase, alpha subunit; hypothetical protein 1698869 14295320 BPP43_08100 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235075.1 1698312 D 1042417 CDS YP_007235076.1 431808178 14295321 1698981..1699664 1 NC_019908.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hypothetical protein 1699664 14295321 BPP43_08105 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235076.1 1698981 D 1042417 CDS YP_007235077.1 431808179 14295322 1699693..1701789 1 NC_019908.1 COG0465 ATP-dependent Zn proteases; ATP-dependent metalloprotease FtsH 1701789 14295322 BPP43_08110 Brachyspira pilosicoli P43/6/78 ATP-dependent metalloprotease FtsH YP_007235077.1 1699693 D 1042417 CDS YP_007235078.1 431808180 14295323 complement(1703566..1704741) 1 NC_019908.1 COG1301 Na+/H+-dicarboxylate symporters; Na+/H+ dicarboxylate symporte 1704741 14295323 BPP43_08125 Brachyspira pilosicoli P43/6/78 Na+/H+ dicarboxylate symporte YP_007235078.1 1703566 R 1042417 CDS YP_007235079.1 431808181 14295324 1704884..1705318 1 NC_019908.1 COG2510 Predicted membrane protein; hypothetical protein 1705318 14295324 BPP43_08130 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235079.1 1704884 D 1042417 CDS YP_007235080.1 431808182 14295325 1705404..1706402 1 NC_019908.1 hypothetical protein 1706402 14295325 BPP43_08135 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235080.1 1705404 D 1042417 CDS YP_007235081.1 431808183 14295326 complement(1706688..1707110) 1 NC_019908.1 hypothetical protein 1707110 14295326 BPP43_08140 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235081.1 1706688 R 1042417 CDS YP_007235082.1 431808184 14295327 complement(1707110..1708096) 1 NC_019908.1 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; aerotolerance-like membrane protein 1708096 14295327 BPP43_08145 Brachyspira pilosicoli P43/6/78 aerotolerance-like membrane protein YP_007235082.1 1707110 R 1042417 CDS YP_007235083.1 431808185 14295329 complement(1708964..1710553) 1 NC_019908.1 COG1543 Uncharacterized conserved protein; family 57 glycoside hydrolase 1710553 14295329 BPP43_08155 Brachyspira pilosicoli P43/6/78 family 57 glycoside hydrolase YP_007235083.1 1708964 R 1042417 CDS YP_007235084.1 431808186 14295330 1710790..1711524 1 NC_019908.1 COG0631 Serine/threonine protein phosphatase; serine threonine protein phosphatase 1711524 14295330 BPP43_08160 Brachyspira pilosicoli P43/6/78 serine threonine protein phosphatase YP_007235084.1 1710790 D 1042417 CDS YP_007235085.1 431808187 14295331 1711617..1711991 1 NC_019908.1 COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); anti sigma factor 1711991 14295331 BPP43_08165 Brachyspira pilosicoli P43/6/78 anti sigma factor YP_007235085.1 1711617 D 1042417 CDS YP_007235086.1 431808188 14295332 1712032..1714092 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1714092 14295332 BPP43_08170 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235086.1 1712032 D 1042417 CDS YP_007235087.1 431808189 14295333 complement(1714162..1714257) 1 NC_019908.1 hypothetical protein 1714257 14295333 BPP43_08175 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235087.1 1714162 R 1042417 CDS YP_007235088.1 431808190 14295334 complement(1714274..1715761) 1 NC_019908.1 COG0733 Na+-dependent transporters of the SNF family; sodium:neurotransmitter symporter 1715761 14295334 BPP43_08180 Brachyspira pilosicoli P43/6/78 sodium:neurotransmitter symporter YP_007235088.1 1714274 R 1042417 CDS YP_007235089.1 431808191 14295336 1716092..1716448 1 NC_019908.1 COG0784 FOG: CheY-like receiver; CheY1 response regulator 1716448 14295336 BPP43_08185 Brachyspira pilosicoli P43/6/78 CheY1 response regulator YP_007235089.1 1716092 D 1042417 CDS YP_007235090.1 431808192 14295337 complement(1716454..1718223) 1 NC_019908.1 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; histidine kinase 1718223 14295337 BPP43_08190 Brachyspira pilosicoli P43/6/78 histidine kinase YP_007235090.1 1716454 R 1042417 CDS YP_007235091.1 431808193 14295338 complement(1718210..1718824) 1 NC_019908.1 COG1011 Predicted hydrolase (HAD superfamily); HAD-superfamily hydrolase 1718824 14295338 BPP43_08195 Brachyspira pilosicoli P43/6/78 HAD-superfamily hydrolase YP_007235091.1 1718210 R 1042417 CDS YP_007235092.1 431808194 14295339 1719096..1720544 1 NC_019908.1 COG1086 Predicted nucleoside-diphosphate sugar epimerases; capsular polysaccharide biosynthesis protein 1720544 14295339 BPP43_08200 Brachyspira pilosicoli P43/6/78 capsular polysaccharide biosynthesis protein YP_007235092.1 1719096 D 1042417 CDS YP_007235093.1 431808195 14295340 1720552..1721403 1 NC_019908.1 COG0169 Shikimate 5-dehydrogenase; shikimate 5-dehydrogenase 1721403 14295340 BPP43_08205 Brachyspira pilosicoli P43/6/78 shikimate 5-dehydrogenase YP_007235093.1 1720552 D 1042417 CDS YP_007235094.1 431808196 14295341 1721424..1722155 1 NC_019908.1 COG0710 3-dehydroquinate dehydratase; 3-dehydroquinate dehydratase 1722155 14295341 BPP43_08210 Brachyspira pilosicoli P43/6/78 3-dehydroquinate dehydratase YP_007235094.1 1721424 D 1042417 CDS YP_007235095.1 431808197 14295342 complement(1722300..1722797) 1 NC_019908.1 hypothetical protein 1722797 14295342 BPP43_08215 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235095.1 1722300 R 1042417 CDS YP_007235096.1 431808198 14295343 complement(1722980..1724335) 1 NC_019908.1 COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH; PhoH family protein 1724335 14295343 BPP43_08220 Brachyspira pilosicoli P43/6/78 PhoH family protein YP_007235096.1 1722980 R 1042417 CDS YP_007235097.1 431808199 14295344 1725181..1726275 1 NC_019908.1 COG1073 Hydrolases of the alpha/beta superfamily; peptidase S15 1726275 14295344 BPP43_08235 Brachyspira pilosicoli P43/6/78 peptidase S15 YP_007235097.1 1725181 D 1042417 CDS YP_007235098.1 431808200 14295345 complement(1727045..1727938) 1 NC_019908.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 1727938 14295345 BPP43_08240 Brachyspira pilosicoli P43/6/78 LysR family transcriptional regulator YP_007235098.1 1727045 R 1042417 CDS YP_007235099.1 431808201 14295346 complement(1728048..1728491) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 1728491 14295346 BPP43_08245 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007235099.1 1728048 R 1042417 CDS YP_007235100.1 431808202 14295347 complement(1728611..1729381) 1 NC_019908.1 hypothetical protein 1729381 14295347 BPP43_08250 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235100.1 1728611 R 1042417 CDS YP_007235101.1 431808203 14295348 complement(1729409..1729768) 1 NC_019908.1 COG1677 Flagellar hook-basal body protein; flagellar hook basal body protein FliE 1729768 14295348 BPP43_08255 Brachyspira pilosicoli P43/6/78 flagellar hook basal body protein FliE YP_007235101.1 1729409 R 1042417 CDS YP_007235102.1 431808204 14295349 complement(1729789..1730250) 1 NC_019908.1 COG1558 Flagellar basal body rod protein; flagellar basal body rod protein FlgC 1730250 14295349 BPP43_08260 Brachyspira pilosicoli P43/6/78 flagellar basal body rod protein FlgC YP_007235102.1 1729789 R 1042417 CDS YP_007235103.1 431808205 14295350 complement(1730281..1730709) 1 NC_019908.1 COG1815 Flagellar basal body protein; flagellar basal body rod protein FlgB 1730709 14295350 BPP43_08265 Brachyspira pilosicoli P43/6/78 flagellar basal body rod protein FlgB YP_007235103.1 1730281 R 1042417 CDS YP_007235104.1 431808206 14295351 complement(1731272..1732465) 1 NC_019908.1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; GntR family transcriptional regulator 1732465 14295351 BPP43_08270 Brachyspira pilosicoli P43/6/78 GntR family transcriptional regulator YP_007235104.1 1731272 R 1042417 CDS YP_007235105.1 431808207 14295352 complement(1732543..1732848) 1 NC_019908.1 hypothetical protein 1732848 14295352 BPP43_08275 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235105.1 1732543 R 1042417 CDS YP_007235106.1 431808208 14295353 complement(1732859..1733065) 1 NC_019908.1 hypothetical protein 1733065 14295353 BPP43_08280 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235106.1 1732859 R 1042417 CDS YP_007235107.1 431808209 14295354 complement(1733078..1733608) 1 NC_019908.1 hypothetical protein 1733608 14295354 BPP43_08285 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235107.1 1733078 R 1042417 CDS YP_007235108.1 431808210 14295355 complement(1733724..1734314) 1 NC_019908.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 1734314 14295355 BPP43_08290 Brachyspira pilosicoli P43/6/78 TetR family transcriptional regulator YP_007235108.1 1733724 R 1042417 CDS YP_007235109.1 431808211 14295356 1734473..1735195 1 NC_019908.1 hypothetical protein 1735195 14295356 BPP43_08295 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235109.1 1734473 D 1042417 CDS YP_007235110.1 431808212 14295357 1735252..1735512 1 NC_019908.1 hypothetical protein 1735512 14295357 BPP43_08300 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235110.1 1735252 D 1042417 CDS YP_007235111.1 431808213 14295359 1735652..1737271 1 NC_019908.1 COG1295 Predicted membrane protein; ribonuclease BN 1737271 14295359 BPP43_08305 Brachyspira pilosicoli P43/6/78 ribonuclease BN YP_007235111.1 1735652 D 1042417 CDS YP_007235112.1 431808214 14295360 complement(1737274..1737888) 1 NC_019908.1 hypothetical protein 1737888 14295360 BPP43_08310 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235112.1 1737274 R 1042417 CDS YP_007235113.1 431808215 14295361 complement(1737894..1739234) 1 NC_019908.1 COG1106 Predicted ATPases; transporter 1739234 14295361 BPP43_08315 Brachyspira pilosicoli P43/6/78 transporter YP_007235113.1 1737894 R 1042417 CDS YP_007235114.1 431808216 14295362 1739380..1740909 1 NC_019908.1 COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1740909 purH 14295362 purH Brachyspira pilosicoli P43/6/78 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_007235114.1 1739380 D 1042417 CDS YP_007235115.1 431808217 14295363 1741024..1741587 1 NC_019908.1 COG0450 Peroxiredoxin; alkyl-hydrogen peroxide reductase 1741587 14295363 BPP43_08325 Brachyspira pilosicoli P43/6/78 alkyl-hydrogen peroxide reductase YP_007235115.1 1741024 D 1042417 CDS YP_007235116.1 431808218 14295364 complement(1741669..1742577) 1 NC_019908.1 COG0331 (acyl-carrier-protein) S-malonyltransferase; malonyl-CoA acyl carrier protein transacylase 1742577 14295364 BPP43_08330 Brachyspira pilosicoli P43/6/78 malonyl-CoA acyl carrier protein transacylase YP_007235116.1 1741669 R 1042417 CDS YP_007235117.1 431808219 14295365 1743248..1744162 1 NC_019908.1 hypothetical protein 1744162 14295365 BPP43_08335 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235117.1 1743248 D 1042417 CDS YP_007235118.1 431808220 14295366 complement(1744159..1744929) 1 NC_019908.1 hypothetical protein 1744929 14295366 BPP43_08340 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235118.1 1744159 R 1042417 CDS YP_007235119.1 431808221 14295367 complement(1744987..1746222) 1 NC_019908.1 hypothetical protein 1746222 14295367 BPP43_08345 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235119.1 1744987 R 1042417 CDS YP_007235120.1 431808222 14295368 complement(1746339..1747223) 1 NC_019908.1 hypothetical protein 1747223 14295368 BPP43_08350 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235120.1 1746339 R 1042417 CDS YP_007235121.1 431808223 14295369 1747846..1748706 1 NC_019908.1 COG1344 Flagellin and related hook-associated proteins; endoflagellar protein, FlaB2 1748706 14295369 BPP43_08355 Brachyspira pilosicoli P43/6/78 endoflagellar protein, FlaB2 YP_007235121.1 1747846 D 1042417 CDS YP_007235122.1 431808224 14295370 complement(1748802..1749428) 1 NC_019908.1 COG1738 Uncharacterized conserved protein; hypothetical protein 1749428 14295370 BPP43_08360 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235122.1 1748802 R 1042417 CDS YP_007235123.1 431808225 14295371 complement(1749538..1749852) 1 NC_019908.1 hypothetical protein 1749852 14295371 BPP43_08365 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235123.1 1749538 R 1042417 CDS YP_007235124.1 431808226 14295372 complement(1749871..1750866) 1 NC_019908.1 viral A-type inclusion protein 1750866 14295372 BPP43_08370 Brachyspira pilosicoli P43/6/78 viral A-type inclusion protein YP_007235124.1 1749871 R 1042417 CDS YP_007235125.1 431808227 14295373 1751065..1752129 1 NC_019908.1 hypothetical protein 1752129 14295373 BPP43_08375 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235125.1 1751065 D 1042417 CDS YP_007235126.1 431808228 14295374 1752320..1752964 1 NC_019908.1 COG0220 Predicted S-adenosylmethionine-dependent methyltransferase; tRNA-(guanine-N(7))-methyltransferase 1752964 14295374 BPP43_08380 Brachyspira pilosicoli P43/6/78 tRNA-(guanine-N(7))-methyltransferase YP_007235126.1 1752320 D 1042417 CDS YP_007235127.1 431808229 14295375 1753053..1753934 1 NC_019908.1 COG0053 Predicted Co/Zn/Cd cation transporters; cation efflux system protein 1753934 14295375 BPP43_08385 Brachyspira pilosicoli P43/6/78 cation efflux system protein YP_007235127.1 1753053 D 1042417 CDS YP_007235128.1 431808230 14295376 1754163..1756076 1 NC_019908.1 COG1256 Flagellar hook-associated protein; flagellar hook-associated protein FlgK 1756076 flgK 14295376 flgK Brachyspira pilosicoli P43/6/78 flagellar hook-associated protein FlgK YP_007235128.1 1754163 D 1042417 CDS YP_007235129.1 431808231 14295377 1756232..1759033 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis sensory transducer 1759033 14295377 BPP43_08395 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis sensory transducer YP_007235129.1 1756232 D 1042417 CDS YP_007235130.1 431808232 14295378 1759107..1761137 1 NC_019908.1 COG0815 Apolipoprotein N-acyltransferase; apolipoprotein N acyltransferase 1761137 14295378 BPP43_08400 Brachyspira pilosicoli P43/6/78 apolipoprotein N acyltransferase YP_007235130.1 1759107 D 1042417 CDS YP_007235131.1 431808233 14295379 1761150..1762286 1 NC_019908.1 COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; glutamate methylesterase CheB 1762286 14295379 BPP43_08405 Brachyspira pilosicoli P43/6/78 glutamate methylesterase CheB YP_007235131.1 1761150 D 1042417 CDS YP_007235132.1 431808234 14295380 1762288..1762776 1 NC_019908.1 hypothetical protein 1762776 14295380 BPP43_08410 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235132.1 1762288 D 1042417 CDS YP_007235133.1 431808235 14295381 1762814..1763221 1 NC_019908.1 hypothetical protein 1763221 14295381 BPP43_08415 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235133.1 1762814 D 1042417 CDS YP_007235134.1 431808236 14295382 complement(1763264..1763695) 1 NC_019908.1 hypothetical protein 1763695 14295382 BPP43_08420 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235134.1 1763264 R 1042417 CDS YP_007235135.1 431808237 14295383 1763832..1765115 1 NC_019908.1 COG0153 Galactokinase; galactokinase 1765115 14295383 BPP43_08425 Brachyspira pilosicoli P43/6/78 galactokinase YP_007235135.1 1763832 D 1042417 CDS YP_007235136.1 431808238 14295384 complement(1765157..1766095) 1 NC_019908.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; family 2 glycosyl transferase 1766095 14295384 BPP43_08430 Brachyspira pilosicoli P43/6/78 family 2 glycosyl transferase YP_007235136.1 1765157 R 1042417 CDS YP_007235137.1 431808239 14295385 complement(1766092..1767123) 1 NC_019908.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 1767123 14295385 BPP43_08435 Brachyspira pilosicoli P43/6/78 NAD-dependent epimerase/dehydratase YP_007235137.1 1766092 R 1042417 CDS YP_007235138.1 431808240 14295386 complement(1767136..1768845) 1 NC_019908.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase large subunit 1768845 14295386 BPP43_08440 Brachyspira pilosicoli P43/6/78 acetolactate synthase large subunit YP_007235138.1 1767136 R 1042417 CDS YP_007235139.1 431808241 14295387 complement(1768858..1770156) 1 NC_019908.1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; lipopolysaccharide biosynthesis protein RfbH 1770156 14295387 BPP43_08445 Brachyspira pilosicoli P43/6/78 lipopolysaccharide biosynthesis protein RfbH YP_007235139.1 1768858 R 1042417 CDS YP_007235140.1 431808242 14295388 complement(1770158..1771222) 1 NC_019908.1 COG0451 Nucleoside-diphosphate-sugar epimerases; CDP-glucose 4,6-dehydratase 1771222 14295388 BPP43_08450 Brachyspira pilosicoli P43/6/78 CDP-glucose 4,6-dehydratase YP_007235140.1 1770158 R 1042417 CDS YP_007235141.1 431808243 14295389 complement(1771204..1771992) 1 NC_019908.1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); glucose-1-phosphate cytidylyltransferase 1771992 14295389 BPP43_08455 Brachyspira pilosicoli P43/6/78 glucose-1-phosphate cytidylyltransferase YP_007235141.1 1771204 R 1042417 CDS YP_007235142.1 431808244 14295390 complement(1772034..1773092) 1 NC_019908.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 1773092 14295390 BPP43_08460 Brachyspira pilosicoli P43/6/78 glycosyltransferase YP_007235142.1 1772034 R 1042417 CDS YP_007235143.1 431808245 14295391 complement(1773092..1773820) 1 NC_019908.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 1773820 14295391 BPP43_08465 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235143.1 1773092 R 1042417 CDS YP_007235144.1 431808246 14295392 complement(1773817..1776708) 1 NC_019908.1 hypothetical protein 1776708 14295392 BPP43_08470 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235144.1 1773817 R 1042417 CDS YP_007235145.1 431808247 14295393 1777965..1778378 1 NC_019908.1 hypothetical protein 1778378 14295393 BPP43_08485 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235145.1 1777965 D 1042417 CDS YP_007235146.1 431808248 14295394 1778719..1780719 1 NC_019908.1 COG0210 Superfamily I DNA and RNA helicases; ATP-dependent DNA helicase 1780719 14295394 BPP43_08490 Brachyspira pilosicoli P43/6/78 ATP-dependent DNA helicase YP_007235146.1 1778719 D 1042417 CDS YP_007235147.1 431808249 14295395 complement(1780716..1781765) 1 NC_019908.1 COG0523 Putative GTPases (G3E family); GTPase 1781765 14295395 BPP43_08495 Brachyspira pilosicoli P43/6/78 GTPase YP_007235147.1 1780716 R 1042417 CDS YP_007235148.1 431808250 14295396 complement(1781887..1782948) 1 NC_019908.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; alcohol dehydrogenase 1782948 14295396 BPP43_08500 Brachyspira pilosicoli P43/6/78 alcohol dehydrogenase YP_007235148.1 1781887 R 1042417 CDS YP_007235149.1 431808251 14295397 complement(1783054..1783440) 1 NC_019908.1 hypothetical protein 1783440 14295397 BPP43_08505 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235149.1 1783054 R 1042417 CDS YP_007235150.1 431808252 14295398 1783605..1784897 1 NC_019908.1 COG0015 Adenylosuccinate lyase; adenylosuccinate lyase 1784897 14295398 BPP43_08510 Brachyspira pilosicoli P43/6/78 adenylosuccinate lyase YP_007235150.1 1783605 D 1042417 CDS YP_007235151.1 431808253 14295399 1785086..1785190 1 NC_019908.1 GNAT family acetyltransferase 1785190 14295399 BPP43_08515 Brachyspira pilosicoli P43/6/78 GNAT family acetyltransferase YP_007235151.1 1785086 D 1042417 CDS YP_007235152.1 431808254 14295400 1785192..1785653 1 NC_019908.1 COG0456 Acetyltransferases; GNAT family acetyltransferase 1785653 14295400 BPP43_08520 Brachyspira pilosicoli P43/6/78 GNAT family acetyltransferase YP_007235152.1 1785192 D 1042417 CDS YP_007235153.1 431808255 14295401 complement(1785650..1786153) 1 NC_019908.1 COG0681 Signal peptidase I; signal peptidase I 1786153 14295401 BPP43_08525 Brachyspira pilosicoli P43/6/78 signal peptidase I YP_007235153.1 1785650 R 1042417 CDS YP_007235154.1 431808256 14295402 complement(1786156..1788846) 1 NC_019908.1 COG0249 Mismatch repair ATPase (MutS family); DNA mismatch repair protein MutS 1788846 14295402 BPP43_08530 Brachyspira pilosicoli P43/6/78 DNA mismatch repair protein MutS YP_007235154.1 1786156 R 1042417 CDS YP_007235155.1 431808257 14295403 complement(1789195..1790451) 1 NC_019908.1 COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases; N-acetyltransferase GCN5 1790451 14295403 BPP43_08535 Brachyspira pilosicoli P43/6/78 N-acetyltransferase GCN5 YP_007235155.1 1789195 R 1042417 CDS YP_007235156.1 431808258 14295404 1790631..1791194 1 NC_019908.1 hypothetical protein 1791194 14295404 BPP43_08540 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235156.1 1790631 D 1042417 CDS YP_007235157.1 431808259 14295405 1791191..1791865 1 NC_019908.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 1791865 14295405 BPP43_08545 Brachyspira pilosicoli P43/6/78 ABC transporter ATP-binding protein YP_007235157.1 1791191 D 1042417 CDS YP_007235158.1 431808260 14295406 1792018..1793367 1 NC_019908.1 COG0334 Glutamate dehydrogenase/leucine dehydrogenase; glutamate dehydrogenase 1793367 14295406 BPP43_08550 Brachyspira pilosicoli P43/6/78 glutamate dehydrogenase YP_007235158.1 1792018 D 1042417 CDS YP_007235159.1 431808261 14295407 complement(1793868..1794932) 1 NC_019908.1 COG0709 Selenophosphate synthase; selenophosphate synthetase 1794932 14295407 BPP43_08555 Brachyspira pilosicoli P43/6/78 selenophosphate synthetase YP_007235159.1 1793868 R 1042417 CDS YP_007235160.1 431808262 14295408 1795088..1795519 1 NC_019908.1 hypothetical protein 1795519 14295408 BPP43_08560 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235160.1 1795088 D 1042417 CDS YP_007235161.1 431808263 14295409 complement(1795697..1795903) 1 NC_019908.1 hypothetical protein 1795903 14295409 BPP43_08565 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235161.1 1795697 R 1042417 CDS YP_007235162.1 431808264 14295410 complement(1795982..1798096) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1798096 14295410 BPP43_08570 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235162.1 1795982 R 1042417 CDS YP_007235163.1 431808265 14295411 complement(1798128..1798448) 1 NC_019908.1 COG0762 Predicted integral membrane protein; hypothetical protein 1798448 14295411 BPP43_08575 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235163.1 1798128 R 1042417 CDS YP_007235164.1 431808266 14295412 complement(1798461..1798793) 1 NC_019908.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); anti sigma regulatory factor 1798793 14295412 BPP43_08580 Brachyspira pilosicoli P43/6/78 anti sigma regulatory factor YP_007235164.1 1798461 R 1042417 CDS YP_007235165.1 431808267 14295413 complement(1798885..1799670) 1 NC_019908.1 COG0708 Exonuclease III; exodeoxyribonuclease 1799670 14295413 BPP43_08585 Brachyspira pilosicoli P43/6/78 exodeoxyribonuclease YP_007235165.1 1798885 R 1042417 CDS YP_007235166.1 431808268 14295414 complement(1799827..1800555) 1 NC_019908.1 COG1126 ABC-type polar amino acid transport system, ATPase component; amino acid transport ATP-binding protein 1800555 14295414 BPP43_08590 Brachyspira pilosicoli P43/6/78 amino acid transport ATP-binding protein YP_007235166.1 1799827 R 1042417 CDS YP_007235167.1 431808269 14295415 complement(1800548..1801261) 1 NC_019908.1 COG0765 ABC-type amino acid transport system, permease component; amino acid transport system permease 1801261 14295415 BPP43_08595 Brachyspira pilosicoli P43/6/78 amino acid transport system permease YP_007235167.1 1800548 R 1042417 CDS YP_007235168.1 431808270 14295416 complement(1801303..1802037) 1 NC_019908.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; family 3 extracellular solute-binding protein 1802037 14295416 BPP43_08600 Brachyspira pilosicoli P43/6/78 family 3 extracellular solute-binding protein YP_007235168.1 1801303 R 1042417 CDS YP_007235169.1 431808271 14295417 complement(1802068..1802802) 1 NC_019908.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; family 3 extracellular solute-binding protein 1802802 14295417 BPP43_08605 Brachyspira pilosicoli P43/6/78 family 3 extracellular solute-binding protein YP_007235169.1 1802068 R 1042417 CDS YP_007235170.1 431808272 14295418 complement(1803021..1803560) 1 NC_019908.1 hypothetical protein 1803560 14295418 BPP43_08610 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235170.1 1803021 R 1042417 CDS YP_007235171.1 431808273 14295419 1803745..1804236 1 NC_019908.1 hypothetical protein 1804236 14295419 BPP43_08615 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235171.1 1803745 D 1042417 CDS YP_007235172.1 431808274 14295420 1804328..1805851 1 NC_019908.1 COG0606 Predicted ATPase with chaperone activity; ATPase 1805851 14295420 BPP43_08620 Brachyspira pilosicoli P43/6/78 ATPase YP_007235172.1 1804328 D 1042417 CDS YP_007235173.1 431808275 14295421 complement(1805906..1806379) 1 NC_019908.1 COG2703 Hemerythrin; hemerythrin-like protein 1806379 14295421 BPP43_08625 Brachyspira pilosicoli P43/6/78 hemerythrin-like protein YP_007235173.1 1805906 R 1042417 CDS YP_007235174.1 431808276 14295422 complement(1807790..1808320) 1 NC_019908.1 COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit; ATP-dependent protease subunit HslV 1808320 14295422 BPP43_08640 Brachyspira pilosicoli P43/6/78 ATP-dependent protease subunit HslV YP_007235174.1 1807790 R 1042417 CDS YP_007235175.1 431808277 14295423 complement(1808827..1809336) 1 NC_019908.1 COG0806 RimM protein, required for 16S rRNA processing; RimM protein 1809336 14295423 BPP43_08645 Brachyspira pilosicoli P43/6/78 RimM protein YP_007235175.1 1808827 R 1042417 CDS YP_007235176.1 431808278 14295424 complement(1809333..1809575) 1 NC_019908.1 COG1837 Predicted RNA-binding protein (contains KH domain); RNA-binding protein 1809575 14295424 BPP43_08650 Brachyspira pilosicoli P43/6/78 RNA-binding protein YP_007235176.1 1809333 R 1042417 CDS YP_007235177.1 431808279 14295425 complement(1809604..1809969) 1 NC_019908.1 COG0228 Ribosomal protein S16; 30S ribosomal protein S16 1809969 14295425 BPP43_08655 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S16 YP_007235177.1 1809604 R 1042417 CDS YP_007235178.1 431808280 14295426 complement(1809989..1811344) 1 NC_019908.1 COG0541 Signal recognition particle GTPase; signal recognition particle GTPase 1811344 14295426 BPP43_08660 Brachyspira pilosicoli P43/6/78 signal recognition particle GTPase YP_007235178.1 1809989 R 1042417 CDS YP_007235179.1 431808281 14295427 1811244..1811348 1 NC_019908.1 hypothetical protein 1811348 14295427 BPP43_08665 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235179.1 1811244 D 1042417 CDS YP_007235180.1 431808282 14295428 1811584..1812078 1 NC_019908.1 hypothetical protein 1812078 14295428 BPP43_08670 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235180.1 1811584 D 1042417 CDS YP_007235181.1 431808283 14295429 1812172..1813563 1 NC_019908.1 COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; amidophosphoribosyltransferase 1813563 14295429 BPP43_08675 Brachyspira pilosicoli P43/6/78 amidophosphoribosyltransferase YP_007235181.1 1812172 D 1042417 CDS YP_007235182.1 431808284 14295430 complement(1813632..1814483) 1 NC_019908.1 COG1253 Hemolysins and related proteins containing CBS domains; hemolysin C 1814483 14295430 BPP43_08680 Brachyspira pilosicoli P43/6/78 hemolysin C YP_007235182.1 1813632 R 1042417 CDS YP_007235183.1 431808285 14295431 complement(1814449..1814910) 1 NC_019908.1 COG0319 Predicted metal-dependent hydrolase; hypothetical protein 1814910 14295431 BPP43_08685 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235183.1 1814449 R 1042417 CDS YP_007235184.1 431808286 14295432 complement(1814912..1817179) 1 NC_019908.1 COG1480 Predicted membrane-associated HD superfamily hydrolase; metal-dependent phosphohydrolase 1817179 14295432 BPP43_08690 Brachyspira pilosicoli P43/6/78 metal-dependent phosphohydrolase YP_007235184.1 1814912 R 1042417 CDS YP_007235185.1 431808287 14295433 complement(1817281..1818039) 1 NC_019908.1 COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; phosphate starvation-inducible protein 1818039 14295433 BPP43_08695 Brachyspira pilosicoli P43/6/78 phosphate starvation-inducible protein YP_007235185.1 1817281 R 1042417 CDS YP_007235186.1 431808288 14295434 1818392..1818844 1 NC_019908.1 COG0346 Lactoylglutathione lyase and related lyases; glyoxalase 1818844 14295434 BPP43_08700 Brachyspira pilosicoli P43/6/78 glyoxalase YP_007235186.1 1818392 D 1042417 CDS YP_007235187.1 431808289 14295435 complement(1818905..1819534) 1 NC_019908.1 COG0740 Protease subunit of ATP-dependent Clp proteases; ATP-dependent Clp protease proteolytic subunit ClpP 1819534 14295435 BPP43_08705 Brachyspira pilosicoli P43/6/78 ATP-dependent Clp protease proteolytic subunit ClpP YP_007235187.1 1818905 R 1042417 CDS YP_007235188.1 431808290 14295436 complement(1819564..1820874) 1 NC_019908.1 COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); trigger factorg protein 1820874 14295436 BPP43_08710 Brachyspira pilosicoli P43/6/78 trigger factorg protein YP_007235188.1 1819564 R 1042417 CDS YP_007235189.1 431808291 14295438 1822190..1823467 1 NC_019908.1 COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; UDP-N-acetylglucosamine 1 carboxyvinyltransferase 1823467 14295438 BPP43_08725 Brachyspira pilosicoli P43/6/78 UDP-N-acetylglucosamine 1 carboxyvinyltransferase YP_007235189.1 1822190 D 1042417 CDS YP_007235190.1 431808292 14295439 1823488..1824336 1 NC_019908.1 COG4786 Flagellar basal body rod protein; flagellar hook-basal body complex protein 1824336 14295439 BPP43_08730 Brachyspira pilosicoli P43/6/78 flagellar hook-basal body complex protein YP_007235190.1 1823488 D 1042417 CDS YP_007235191.1 431808293 14295440 1824415..1827345 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein B 1827345 14295440 BPP43_08735 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis protein B YP_007235191.1 1824415 D 1042417 CDS YP_007235192.1 431808294 14295441 1827504..1828610 1 NC_019908.1 COG0787 Alanine racemase; alanine racemase 1828610 14295441 BPP43_08740 Brachyspira pilosicoli P43/6/78 alanine racemase YP_007235192.1 1827504 D 1042417 CDS YP_007235193.1 431808295 14295442 1828693..1830066 1 NC_019908.1 COG1115 Na+/alanine symporter; sodium/alanine symporter 1830066 14295442 BPP43_08745 Brachyspira pilosicoli P43/6/78 sodium/alanine symporter YP_007235193.1 1828693 D 1042417 CDS YP_007235194.1 431808296 14295443 complement(1830186..1830716) 1 NC_019908.1 COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain; fumarate hydratase 1830716 14295443 BPP43_08750 Brachyspira pilosicoli P43/6/78 fumarate hydratase YP_007235194.1 1830186 R 1042417 CDS YP_007235195.1 431808297 14295444 complement(1830761..1831603) 1 NC_019908.1 COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; fumarate hydratase 1831603 14295444 BPP43_08755 Brachyspira pilosicoli P43/6/78 fumarate hydratase YP_007235195.1 1830761 R 1042417 CDS YP_007235196.1 431808298 14295445 1832354..1833619 1 NC_019908.1 hypothetical protein 1833619 14295445 BPP43_08760 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235196.1 1832354 D 1042417 CDS YP_007235197.1 431808299 14295446 1833625..1834284 1 NC_019908.1 hypothetical protein 1834284 14295446 BPP43_08765 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235197.1 1833625 D 1042417 CDS YP_007235198.1 431808300 14295447 1834317..1835207 1 NC_019908.1 COG0657 Esterase/lipase; esterase 1835207 14295447 BPP43_08770 Brachyspira pilosicoli P43/6/78 esterase YP_007235198.1 1834317 D 1042417 CDS YP_007235199.1 431808301 14295448 complement(1835732..1837042) 1 NC_019908.1 COG2252 Permeases; integral membrane transport protein 1837042 14295448 BPP43_08775 Brachyspira pilosicoli P43/6/78 integral membrane transport protein YP_007235199.1 1835732 R 1042417 CDS YP_007235200.1 431808302 14295449 complement(1837217..1837468) 1 NC_019908.1 hypothetical protein 1837468 14295449 BPP43_08780 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235200.1 1837217 R 1042417 CDS YP_007235201.1 431808303 14295450 complement(1837498..1837749) 1 NC_019908.1 hypothetical protein 1837749 14295450 BPP43_08785 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235201.1 1837498 R 1042417 CDS YP_007235202.1 431808304 14295451 complement(1837784..1838299) 1 NC_019908.1 hypothetical protein 1838299 14295451 BPP43_08790 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235202.1 1837784 R 1042417 CDS YP_007235203.1 431808305 14295452 1838760..1840118 1 NC_019908.1 COG1538 Outer membrane protein; outer membrane protein TolC 1840118 14295452 BPP43_08795 Brachyspira pilosicoli P43/6/78 outer membrane protein TolC YP_007235203.1 1838760 D 1042417 CDS YP_007235204.1 431808306 14295453 1840132..1841469 1 NC_019908.1 COG0845 Membrane-fusion protein; membrane fusion protein 1841469 14295453 BPP43_08800 Brachyspira pilosicoli P43/6/78 membrane fusion protein YP_007235204.1 1840132 D 1042417 CDS YP_007235205.1 431808307 14295454 1841509..1844649 1 NC_019908.1 COG0841 Cation/multidrug efflux pump; acriflavin resistance protein 1844649 14295454 BPP43_08805 Brachyspira pilosicoli P43/6/78 acriflavin resistance protein YP_007235205.1 1841509 D 1042417 CDS YP_007235206.1 431808308 14295455 1844940..1846493 1 NC_019908.1 COG2978 Putative p-aminobenzoyl-glutamate transporter; aminobenzoyl-glutamate transport protein 1846493 14295455 BPP43_08810 Brachyspira pilosicoli P43/6/78 aminobenzoyl-glutamate transport protein YP_007235206.1 1844940 D 1042417 CDS YP_007235207.1 431808309 14295456 1846519..1847709 1 NC_019908.1 COG0006 Xaa-Pro aminopeptidase; peptidase 1847709 14295456 BPP43_08815 Brachyspira pilosicoli P43/6/78 peptidase YP_007235207.1 1846519 D 1042417 CDS YP_007235208.1 431808310 14295457 complement(1847980..1848636) 1 NC_019908.1 hypothetical protein 1848636 14295457 BPP43_08820 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235208.1 1847980 R 1042417 CDS YP_007235209.1 431808311 14295458 1848968..1849255 1 NC_019908.1 hypothetical protein 1849255 14295458 BPP43_08825 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235209.1 1848968 D 1042417 CDS YP_007235210.1 431808312 14295459 1849366..1851858 1 NC_019908.1 COG1918 Fe2+ transport system protein A; ferrous iron transport protein B 1851858 14295459 BPP43_08830 Brachyspira pilosicoli P43/6/78 ferrous iron transport protein B YP_007235210.1 1849366 D 1042417 CDS YP_007235211.1 431808313 14295460 complement(1851939..1853063) 1 NC_019908.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycoslytransferase 1853063 14295460 BPP43_08835 Brachyspira pilosicoli P43/6/78 glycoslytransferase YP_007235211.1 1851939 R 1042417 CDS YP_007235212.1 431808314 14295461 1854415..1854927 1 NC_019908.1 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; thioesterase 1854927 14295461 BPP43_08850 Brachyspira pilosicoli P43/6/78 thioesterase YP_007235212.1 1854415 D 1042417 CDS YP_007235213.1 431808315 14295462 complement(1855158..1855928) 1 NC_019908.1 COG0431 Predicted flavoprotein; hypothetical protein 1855928 14295462 BPP43_08855 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235213.1 1855158 R 1042417 CDS YP_007235214.1 431808316 14295463 complement(1856401..1858392) 1 NC_019908.1 COG0210 Superfamily I DNA and RNA helicases; ATP dependent DNA helicase 1858392 14295463 BPP43_08860 Brachyspira pilosicoli P43/6/78 ATP dependent DNA helicase YP_007235214.1 1856401 R 1042417 CDS YP_007235215.1 431808317 14295464 complement(1858820..1859782) 1 NC_019908.1 COG3458 Acetyl esterase (deacetylase); acetyl-xylan esterase 1859782 14295464 BPP43_08865 Brachyspira pilosicoli P43/6/78 acetyl-xylan esterase YP_007235215.1 1858820 R 1042417 CDS YP_007235216.1 431808318 14295465 complement(1859795..1860589) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1860589 14295465 BPP43_08870 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235216.1 1859795 R 1042417 CDS YP_007235217.1 431808319 14295466 complement(1860673..1861467) 1 NC_019908.1 COG0024 Methionine aminopeptidase; methionine aminopeptidase 1861467 14295466 BPP43_08875 Brachyspira pilosicoli P43/6/78 methionine aminopeptidase YP_007235217.1 1860673 R 1042417 CDS YP_007235218.1 431808320 14295467 complement(1861490..1861927) 1 NC_019908.1 COG1664 Integral membrane protein CcmA involved in cell shape determination; hypothetical protein 1861927 14295467 BPP43_08880 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235218.1 1861490 R 1042417 CDS YP_007235219.1 431808321 14295468 1862127..1862801 1 NC_019908.1 hypothetical protein 1862801 14295468 BPP43_08885 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235219.1 1862127 D 1042417 CDS YP_007235220.1 431808322 14295469 1862822..1863370 1 NC_019908.1 COG0742 N6-adenine-specific methylase; yhhF N6 adenine specific methylase 1863370 14295469 BPP43_08890 Brachyspira pilosicoli P43/6/78 yhhF N6 adenine specific methylase YP_007235220.1 1862822 D 1042417 CDS YP_007235221.1 431808323 14295470 1863421..1864512 1 NC_019908.1 hypothetical protein 1864512 14295470 BPP43_08895 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235221.1 1863421 D 1042417 CDS YP_007235222.1 431808324 14295471 1864925..1865290 1 NC_019908.1 COG1380 Putative effector of murein hydrolase LrgA; effector of murein hydrolase LrgA 1865290 14295471 BPP43_08900 Brachyspira pilosicoli P43/6/78 effector of murein hydrolase LrgA YP_007235222.1 1864925 D 1042417 CDS YP_007235223.1 431808325 14295472 1865287..1865994 1 NC_019908.1 COG1346 Putative effector of murein hydrolase; LrgB like family protein 1865994 14295472 BPP43_08905 Brachyspira pilosicoli P43/6/78 LrgB like family protein YP_007235223.1 1865287 D 1042417 CDS YP_007235224.1 431808326 14295473 complement(1866214..1867059) 1 NC_019908.1 COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase 1867059 14295473 BPP43_08910 Brachyspira pilosicoli P43/6/78 methylenetetrahydrofolate dehydrogenase YP_007235224.1 1866214 R 1042417 CDS YP_007235225.1 431808327 14295474 complement(1867241..1867627) 1 NC_019908.1 COG0735 Fe2+/Zn2+ uptake regulation proteins; ferric uptake regulator 1867627 14295474 BPP43_08915 Brachyspira pilosicoli P43/6/78 ferric uptake regulator YP_007235225.1 1867241 R 1042417 CDS YP_007235226.1 431808328 14295475 complement(1867724..1868632) 1 NC_019908.1 COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; D-alanine--D-alanine ligase 1868632 14295475 BPP43_08920 Brachyspira pilosicoli P43/6/78 D-alanine--D-alanine ligase YP_007235226.1 1867724 R 1042417 CDS YP_007235227.1 431808329 14295476 complement(1868754..1869044) 1 NC_019908.1 hypothetical protein 1869044 14295476 BPP43_08925 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235227.1 1868754 R 1042417 CDS YP_007235228.1 431808330 14293875 complement(1869044..1869841) 1 NC_019908.1 hypothetical protein 1869841 14293875 BPP43_08930 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235228.1 1869044 R 1042417 CDS YP_007235229.1 431808331 14293876 complement(1869851..1870468) 1 NC_019908.1 COG1413 FOG: HEAT repeat; hypothetical protein 1870468 14293876 BPP43_08935 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235229.1 1869851 R 1042417 CDS YP_007235230.1 431808332 14293877 complement(1870469..1873063) 1 NC_019908.1 COG0013 Alanyl-tRNA synthetase; alanyl-tRNA synthetase 1873063 14293877 BPP43_08940 Brachyspira pilosicoli P43/6/78 alanyl-tRNA synthetase YP_007235230.1 1870469 R 1042417 CDS YP_007235231.1 431808333 14293878 1873271..1874305 1 NC_019908.1 alpha-1,2-fucosyltransferase 1874305 14293878 BPP43_08945 Brachyspira pilosicoli P43/6/78 alpha-1,2-fucosyltransferase YP_007235231.1 1873271 D 1042417 CDS YP_007235232.1 431808334 14293879 complement(1874338..1875336) 1 NC_019908.1 glyocosyltransferase protein 1875336 14293879 BPP43_08950 Brachyspira pilosicoli P43/6/78 glyocosyltransferase protein YP_007235232.1 1874338 R 1042417 CDS YP_007235233.1 431808335 14293880 1876652..1877704 1 NC_019908.1 alpha-1,2-fucosyltransferase 1877704 14293880 BPP43_08965 Brachyspira pilosicoli P43/6/78 alpha-1,2-fucosyltransferase YP_007235233.1 1876652 D 1042417 CDS YP_007235234.1 431808336 14293881 1877781..1878386 1 NC_019908.1 COG0607 Rhodanese-related sulfurtransferase; rhodanese-like protein 1878386 14293881 BPP43_08970 Brachyspira pilosicoli P43/6/78 rhodanese-like protein YP_007235234.1 1877781 D 1042417 CDS YP_007235235.1 431808337 14293882 complement(1878469..1879860) 1 NC_019908.1 COG1823 Predicted Na+/dicarboxylate symporter; sodium:dicarboxylate symporter 1879860 14293882 BPP43_08975 Brachyspira pilosicoli P43/6/78 sodium:dicarboxylate symporter YP_007235235.1 1878469 R 1042417 CDS YP_007235236.1 431808338 14293883 1880326..1880922 1 NC_019908.1 COG2137 Uncharacterized protein conserved in bacteria; recombination regulator RecX 1880922 14293883 BPP43_08980 Brachyspira pilosicoli P43/6/78 recombination regulator RecX YP_007235236.1 1880326 D 1042417 CDS YP_007235237.1 431808339 14293884 1881088..1881909 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 1881909 14293884 BPP43_08985 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007235237.1 1881088 D 1042417 CDS YP_007235238.1 431808340 14293885 1881914..1882699 1 NC_019908.1 COG2887 RecB family exonuclease; hypothetical protein 1882699 14293885 BPP43_08990 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235238.1 1881914 D 1042417 CDS YP_007235239.1 431808341 14293886 complement(1882696..1883022) 1 NC_019908.1 cupin 1883022 14293886 BPP43_08995 Brachyspira pilosicoli P43/6/78 cupin YP_007235239.1 1882696 R 1042417 CDS YP_007235240.1 431808342 14293887 1883259..1884038 1 NC_019908.1 COG0313 Predicted methyltransferases; tetrapyrrole methyltransferase family protein 1884038 14293887 BPP43_09000 Brachyspira pilosicoli P43/6/78 tetrapyrrole methyltransferase family protein YP_007235240.1 1883259 D 1042417 CDS YP_007235241.1 431808343 14293888 1884028..1884324 1 NC_019908.1 hypothetical protein 1884324 14293888 BPP43_09005 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235241.1 1884028 D 1042417 CDS YP_007235242.1 431808344 14293889 complement(1884407..1885369) 1 NC_019908.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system regulator 1885369 14293889 BPP43_09010 Brachyspira pilosicoli P43/6/78 two-component system regulator YP_007235242.1 1884407 R 1042417 CDS YP_007235243.1 431808345 14293890 complement(1885374..1886114) 1 NC_019908.1 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 1886114 14293890 BPP43_09015 Brachyspira pilosicoli P43/6/78 signal transduction histidine kinase YP_007235243.1 1885374 R 1042417 CDS YP_007235244.1 431808346 14293891 1886647..1887447 1 NC_019908.1 hypothetical protein 1887447 14293891 BPP43_09020 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235244.1 1886647 D 1042417 CDS YP_007235245.1 431808347 14293892 1887444..1889045 1 NC_019908.1 hypothetical protein 1889045 14293892 BPP43_09025 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235245.1 1887444 D 1042417 CDS YP_007235246.1 431808348 14293893 1889310..1890188 1 NC_019908.1 Hvp 32 VSH-1 tail protein 1890188 14293893 BPP43_09030 Brachyspira pilosicoli P43/6/78 Hvp 32 VSH-1 tail protein YP_007235246.1 1889310 D 1042417 CDS YP_007235247.1 431808349 14293894 1890376..1892781 1 NC_019908.1 Hvp 101 VSH-1 tail protein 1892781 14293894 BPP43_09035 Brachyspira pilosicoli P43/6/78 Hvp 101 VSH-1 tail protein YP_007235247.1 1890376 D 1042417 CDS YP_007235248.1 431808350 14293895 1892783..1893379 1 NC_019908.1 Hvp 28 VSH-1 tail protein-like protein 1893379 14293895 BPP43_09040 Brachyspira pilosicoli P43/6/78 Hvp 28 VSH-1 tail protein-like protein YP_007235248.1 1892783 D 1042417 CDS YP_007235249.1 431808351 14293896 1893391..1893969 1 NC_019908.1 COG3179 Predicted chitinase; endolysin glycoside hydrolase 1893969 14293896 BPP43_09045 Brachyspira pilosicoli P43/6/78 endolysin glycoside hydrolase YP_007235249.1 1893391 D 1042417 CDS YP_007235250.1 431808352 14293897 1893981..1894445 1 NC_019908.1 COG1196 Chromosome segregation ATPases; hypothetical protein 1894445 14293897 BPP43_09050 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235250.1 1893981 D 1042417 CDS YP_007235251.1 431808353 14293898 1894452..1894730 1 NC_019908.1 hypothetical protein 1894730 14293898 BPP43_09055 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235251.1 1894452 D 1042417 CDS YP_007235252.1 431808354 14293899 1894699..1895028 1 NC_019908.1 VSH-1 protein OrfG 1895028 14293899 BPP43_09060 Brachyspira pilosicoli P43/6/78 VSH-1 protein OrfG YP_007235252.1 1894699 D 1042417 CDS YP_007235253.1 431808355 14293900 1895067..1895246 1 NC_019908.1 hypothetical protein 1895246 14293900 BPP43_09065 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235253.1 1895067 D 1042417 CDS YP_007235254.1 431808356 14293901 1895672..1896883 1 NC_019908.1 Hvp45 protein 1896883 14293901 BPP43_09070 Brachyspira pilosicoli P43/6/78 Hvp45 protein YP_007235254.1 1895672 D 1042417 CDS YP_007235255.1 431808357 14293902 1897045..1897929 1 NC_019908.1 Hvp 19 VSH 1 associated protein 1 1897929 14293902 BPP43_09075 Brachyspira pilosicoli P43/6/78 Hvp 19 VSH 1 associated protein 1 YP_007235255.1 1897045 D 1042417 CDS YP_007235256.1 431808358 14293903 1898190..1898552 1 NC_019908.1 Hvp 13 VSH 1 associated protein 2 1898552 14293903 BPP43_09080 Brachyspira pilosicoli P43/6/78 Hvp 13 VSH 1 associated protein 2 YP_007235256.1 1898190 D 1042417 CDS YP_007235257.1 431808359 14293904 1898575..1899624 1 NC_019908.1 VSH 1 associated protein 3 virus of Serpulina hyodysenteriae 1899624 14293904 BPP43_09085 Brachyspira pilosicoli P43/6/78 VSH 1 associated protein 3 virus of Serpulina hyodysenteriae YP_007235257.1 1898575 D 1042417 CDS YP_007235258.1 431808360 14293905 1899733..1900032 1 NC_019908.1 hypothetical protein 1900032 14293905 BPP43_09090 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235258.1 1899733 D 1042417 CDS YP_007235259.1 431808361 14293906 1900426..1900803 1 NC_019908.1 hypothetical protein 1900803 14293906 BPP43_09095 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235259.1 1900426 D 1042417 CDS YP_007235260.1 431808362 14293907 1900850..1901413 1 NC_019908.1 Hvp 24 VSH 1 capsid protein 1901413 14293907 BPP43_09100 Brachyspira pilosicoli P43/6/78 Hvp 24 VSH 1 capsid protein YP_007235260.1 1900850 D 1042417 CDS YP_007235261.1 431808363 14293908 1901391..1901660 1 NC_019908.1 hypothetical protein 1901660 14293908 BPP43_09105 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235261.1 1901391 D 1042417 CDS YP_007235262.1 431808364 14293909 1901695..1903065 1 NC_019908.1 Hvp 53 protein 1903065 14293909 BPP43_09110 Brachyspira pilosicoli P43/6/78 Hvp 53 protein YP_007235262.1 1901695 D 1042417 CDS YP_007235263.1 431808365 14293910 1903854..1904213 1 NC_019908.1 COG1309 Transcriptional regulator; VSH-1 protein OrfE 1904213 14293910 BPP43_09115 Brachyspira pilosicoli P43/6/78 VSH-1 protein OrfE YP_007235263.1 1903854 D 1042417 CDS YP_007235264.1 431808366 14293911 1904249..1904488 1 NC_019908.1 hypothetical protein 1904488 14293911 BPP43_09120 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235264.1 1904249 D 1042417 CDS YP_007235265.1 431808367 14293912 1904558..1905556 1 NC_019908.1 COG2055 Malate/L-lactate dehydrogenases; ureidoglycolate dehydrogenase 1905556 14293912 BPP43_09125 Brachyspira pilosicoli P43/6/78 ureidoglycolate dehydrogenase YP_007235265.1 1904558 D 1042417 CDS YP_007235266.1 431808368 14293913 complement(1905745..1906323) 1 NC_019908.1 COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; phosphoribosylglycinamide formyltransferase 1906323 14293913 BPP43_09130 Brachyspira pilosicoli P43/6/78 phosphoribosylglycinamide formyltransferase YP_007235266.1 1905745 R 1042417 CDS YP_007235267.1 431808369 14293914 complement(1906311..1907321) 1 NC_019908.1 COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; phosphoribosylaminoimidazole synthetase 1907321 14293914 BPP43_09135 Brachyspira pilosicoli P43/6/78 phosphoribosylaminoimidazole synthetase YP_007235267.1 1906311 R 1042417 CDS YP_007235268.1 431808370 14293915 1907697..1908533 1 NC_019908.1 COG1344 Flagellin and related hook-associated proteins; flagellin domain-containing protein 1908533 14293915 BPP43_09140 Brachyspira pilosicoli P43/6/78 flagellin domain-containing protein YP_007235268.1 1907697 D 1042417 CDS YP_007235269.1 431808371 14293916 1909406..1909522 1 NC_019908.1 hypothetical protein 1909522 14293916 BPP43_09145 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235269.1 1909406 D 1042417 CDS YP_007235270.1 431808372 14293917 1909686..1910432 1 NC_019908.1 COG0217 Uncharacterized conserved protein; hypothetical protein 1910432 14293917 BPP43_09150 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235270.1 1909686 D 1042417 CDS YP_007235271.1 431808373 14293918 1910442..1910915 1 NC_019908.1 COG0817 Holliday junction resolvasome, endonuclease subunit; crossover junction endodeoxyribonuclease RuvC 1910915 14293918 BPP43_09155 Brachyspira pilosicoli P43/6/78 crossover junction endodeoxyribonuclease RuvC YP_007235271.1 1910442 D 1042417 CDS YP_007235272.1 431808374 14293919 complement(1910959..1911369) 1 NC_019908.1 COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); holliday junction resolvase-like protein 1911369 14293919 BPP43_09160 Brachyspira pilosicoli P43/6/78 holliday junction resolvase-like protein YP_007235272.1 1910959 R 1042417 CDS YP_007235273.1 431808375 14293920 complement(1911405..1912637) 1 NC_019908.1 COG0826 Collagenase and related proteases; peptidase U32 1912637 14293920 BPP43_09165 Brachyspira pilosicoli P43/6/78 peptidase U32 YP_007235273.1 1911405 R 1042417 CDS YP_007235274.1 431808376 14293921 1912828..1914498 1 NC_019908.1 zinc finger SIM domain-containing protein 1914498 14293921 BPP43_09170 Brachyspira pilosicoli P43/6/78 zinc finger SIM domain-containing protein YP_007235274.1 1912828 D 1042417 CDS YP_007235275.1 431808377 14293922 complement(1914879..1916036) 1 NC_019908.1 hypothetical protein 1916036 14293922 BPP43_09175 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235275.1 1914879 R 1042417 CDS YP_007235276.1 431808378 14293923 1916497..1917387 1 NC_019908.1 COG1335 Amidases related to nicotinamidase; nicotinamidase 1917387 14293923 BPP43_09180 Brachyspira pilosicoli P43/6/78 nicotinamidase YP_007235276.1 1916497 D 1042417 CDS YP_007235277.1 431808379 14293924 complement(1917609..1918376) 1 NC_019908.1 COG0846 NAD-dependent protein deacetylases, SIR2 family; deacetylase 1918376 14293924 BPP43_09185 Brachyspira pilosicoli P43/6/78 deacetylase YP_007235277.1 1917609 R 1042417 CDS YP_007235278.1 431808380 14293925 1918628..1919275 1 NC_019908.1 COG2344 AT-rich DNA-binding protein; redox-sensing transcriptional repressor Rex 1919275 14293925 BPP43_09190 Brachyspira pilosicoli P43/6/78 redox-sensing transcriptional repressor Rex YP_007235278.1 1918628 D 1042417 CDS YP_007235279.1 431808381 14293926 1919289..1919990 1 NC_019908.1 COG0671 Membrane-associated phospholipid phosphatase; phosphoesterase 1919990 14293926 BPP43_09195 Brachyspira pilosicoli P43/6/78 phosphoesterase YP_007235279.1 1919289 D 1042417 CDS YP_007235280.1 431808382 14293927 1920004..1921164 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 1921164 14293927 BPP43_09200 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235280.1 1920004 D 1042417 CDS YP_007235281.1 431808383 14293928 1921468..1922322 1 NC_019908.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; membrane protein transporter 1922322 14293928 BPP43_09205 Brachyspira pilosicoli P43/6/78 membrane protein transporter YP_007235281.1 1921468 D 1042417 CDS YP_007235282.1 431808384 14293929 1922492..1922671 1 NC_019908.1 hypothetical protein 1922671 14293929 BPP43_09210 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235282.1 1922492 D 1042417 CDS YP_007235283.1 431808385 14293930 1922691..1922981 1 NC_019908.1 hypothetical protein 1922981 14293930 BPP43_09215 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235283.1 1922691 D 1042417 CDS YP_007235284.1 431808386 14293931 1923024..1923236 1 NC_019908.1 hypothetical protein 1923236 14293931 BPP43_09220 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235284.1 1923024 D 1042417 CDS YP_007235285.1 431808387 14293932 1923322..1925268 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 1925268 14293932 BPP43_09225 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007235285.1 1923322 D 1042417 CDS YP_007235286.1 431808388 14293933 complement(1926966..1927640) 1 NC_019908.1 COG0313 Predicted methyltransferases; tetrapyrrole (corrin/porphyrin) methylase 1927640 14293933 BPP43_09240 Brachyspira pilosicoli P43/6/78 tetrapyrrole (corrin/porphyrin) methylase YP_007235286.1 1926966 R 1042417 CDS YP_007235287.1 431808389 14293934 complement(1927645..1928688) 1 NC_019908.1 COG3023 Negative regulator of beta-lactamase expression; N-acetylmuramoyl-L-alanine amidase 1928688 14293934 BPP43_09245 Brachyspira pilosicoli P43/6/78 N-acetylmuramoyl-L-alanine amidase YP_007235287.1 1927645 R 1042417 CDS YP_007235288.1 431808390 14293935 complement(1928681..1929985) 1 NC_019908.1 hypothetical protein 1929985 14293935 BPP43_09250 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235288.1 1928681 R 1042417 CDS YP_007235289.1 431808391 14293936 complement(1930155..1931303) 1 NC_019908.1 COG5542 Predicted integral membrane protein; hypothetical protein 1931303 14293936 BPP43_09255 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235289.1 1930155 R 1042417 CDS YP_007235290.1 431808392 14293937 1931435..1932238 1 NC_019908.1 COG2362 D-aminopeptidase; thermostable D-stereospecific amino acid amidase 1932238 14293937 BPP43_09260 Brachyspira pilosicoli P43/6/78 thermostable D-stereospecific amino acid amidase YP_007235290.1 1931435 D 1042417 CDS YP_007235291.1 431808393 14293938 1932353..1933453 1 NC_019908.1 COG0136 Aspartate-semialdehyde dehydrogenase; aspartate semialdehyde dehydrogenase 1933453 14293938 BPP43_09265 Brachyspira pilosicoli P43/6/78 aspartate semialdehyde dehydrogenase YP_007235291.1 1932353 D 1042417 CDS YP_007235292.1 431808394 14293939 1933760..1934713 1 NC_019908.1 COG2234 Predicted aminopeptidases; leucine aminopeptidase 1934713 14293939 BPP43_09270 Brachyspira pilosicoli P43/6/78 leucine aminopeptidase YP_007235292.1 1933760 D 1042417 CDS YP_007235293.1 431808395 14293940 1934844..1936685 1 NC_019908.1 COG0534 Na+-driven multidrug efflux pump; MATE efflux family protein 1936685 14293940 BPP43_09275 Brachyspira pilosicoli P43/6/78 MATE efflux family protein YP_007235293.1 1934844 D 1042417 CDS YP_007235294.1 431808396 14293941 1936672..1937385 1 NC_019908.1 COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1937385 14293941 BPP43_09280 Brachyspira pilosicoli P43/6/78 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_007235294.1 1936672 D 1042417 CDS YP_007235295.1 431808397 14293942 1937527..1941972 1 NC_019908.1 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; hypothetical protein 1941972 14293942 BPP43_09285 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235295.1 1937527 D 1042417 CDS YP_007235296.1 431808398 14293943 1941972..1944590 1 NC_019908.1 COG4775 Outer membrane protein/protective antigen OMA87; outer membrane protein 1944590 14293943 BPP43_09290 Brachyspira pilosicoli P43/6/78 outer membrane protein YP_007235296.1 1941972 D 1042417 CDS YP_007235297.1 431808399 14293944 1944676..1945104 1 NC_019908.1 COG2825 Outer membrane protein; outer membrane chaperone OmpH 1945104 14293944 BPP43_09295 Brachyspira pilosicoli P43/6/78 outer membrane chaperone OmpH YP_007235297.1 1944676 D 1042417 CDS YP_007235298.1 431808400 14293945 1945457..1946512 1 NC_019908.1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; ribosomal large subunit pseudouridine synthase B 1946512 14293945 BPP43_09300 Brachyspira pilosicoli P43/6/78 ribosomal large subunit pseudouridine synthase B YP_007235298.1 1945457 D 1042417 CDS YP_007235299.1 431808401 14293946 1946729..1947853 1 NC_019908.1 surface antigen BspA-like protein 1947853 14293946 BPP43_09305 Brachyspira pilosicoli P43/6/78 surface antigen BspA-like protein YP_007235299.1 1946729 D 1042417 CDS YP_007235300.1 431808402 14293947 1948004..1949695 1 NC_019908.1 COG1109 Phosphomannomutase; phosphoglucomutase 1949695 14293947 BPP43_09310 Brachyspira pilosicoli P43/6/78 phosphoglucomutase YP_007235300.1 1948004 D 1042417 CDS YP_007235301.1 431808403 14293948 1950057..1950557 1 NC_019908.1 COG0693 Putative intracellular protease/amidase; PfpI family intracellular peptidase 1950557 14293948 BPP43_09315 Brachyspira pilosicoli P43/6/78 PfpI family intracellular peptidase YP_007235301.1 1950057 D 1042417 CDS YP_007235302.1 431808404 14293949 complement(1950830..1952434) 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter substrate-binding protein 1952434 14293949 BPP43_09320 Brachyspira pilosicoli P43/6/78 oligopeptide ABC transporter substrate-binding protein YP_007235302.1 1950830 R 1042417 CDS YP_007235303.1 431808405 14293950 1952591..1953718 1 NC_019908.1 COG0732 Restriction endonuclease S subunits; type I restriction system specificity protein 1953718 14293950 BPP43_09325 Brachyspira pilosicoli P43/6/78 type I restriction system specificity protein YP_007235303.1 1952591 D 1042417 CDS YP_007235304.1 431808406 14293951 complement(1953957..1955648) 1 NC_019908.1 COG1652 Uncharacterized protein containing LysM domain; hypothetical protein 1955648 14293951 BPP43_09330 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235304.1 1953957 R 1042417 CDS YP_007235305.1 431808407 14293952 complement(1955681..1956301) 1 NC_019908.1 hypothetical protein 1956301 14293952 BPP43_09335 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235305.1 1955681 R 1042417 CDS YP_007235306.1 431808408 14293954 1956790..1957782 1 NC_019908.1 COG2089 Sialic acid synthase; spore coat polysaccharide biosynthesis protein E 1957782 14293954 BPP43_09345 Brachyspira pilosicoli P43/6/78 spore coat polysaccharide biosynthesis protein E YP_007235306.1 1956790 D 1042417 CDS YP_007235307.1 431808409 14293955 1957905..1958795 1 NC_019908.1 hypothetical protein 1958795 14293955 BPP43_09350 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235307.1 1957905 D 1042417 CDS YP_007235308.1 431808410 14293956 1958922..1960370 1 NC_019908.1 COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; glutamyl-tRNA(Gln) amidotransferase subunit A 1960370 14293956 BPP43_09355 Brachyspira pilosicoli P43/6/78 glutamyl-tRNA(Gln) amidotransferase subunit A YP_007235308.1 1958922 D 1042417 CDS YP_007235309.1 431808411 14293957 1960540..1961730 1 NC_019908.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 1961730 14293957 BPP43_09360 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235309.1 1960540 D 1042417 CDS YP_007235310.1 431808412 14293958 complement(1961727..1961969) 1 NC_019908.1 COG1251 NAD(P)H-nitrite reductase; [2Fe-2S]-binding domain-containing protein 1961969 14293958 BPP43_09365 Brachyspira pilosicoli P43/6/78 [2Fe-2S]-binding domain-containing protein YP_007235310.1 1961727 R 1042417 CDS YP_007235311.1 431808413 14293959 complement(1962040..1962978) 1 NC_019908.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD+dependent epimerase dehydratase 1962978 14293959 BPP43_09370 Brachyspira pilosicoli P43/6/78 NAD+dependent epimerase dehydratase YP_007235311.1 1962040 R 1042417 CDS YP_007235312.1 431808414 14293960 complement(1963405..1964154) 1 NC_019908.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-ketoacyl-ACP reductase 1964154 14293960 BPP43_09375 Brachyspira pilosicoli P43/6/78 3-ketoacyl-ACP reductase YP_007235312.1 1963405 R 1042417 CDS YP_007235313.1 431808415 14293961 1964379..1965029 1 NC_019908.1 COG3201 Nicotinamide mononucleotide transporter; nicotinamide-mononucleotide transporter 1965029 14293961 BPP43_09380 Brachyspira pilosicoli P43/6/78 nicotinamide-mononucleotide transporter YP_007235313.1 1964379 D 1042417 CDS YP_007235314.1 431808416 14293962 1965050..1966063 1 NC_019908.1 COG1056 Nicotinamide mononucleotide adenylyltransferase; nicotinamide-nucleotide adenylyltransferase 1966063 14293962 BPP43_09385 Brachyspira pilosicoli P43/6/78 nicotinamide-nucleotide adenylyltransferase YP_007235314.1 1965050 D 1042417 CDS YP_007235315.1 431808417 14293963 1966228..1966584 1 NC_019908.1 COG0232 dGTP triphosphohydrolase; deoxyguanosinetriphosphate triphosphohydrolase-like protein 1966584 14293963 BPP43_09390 Brachyspira pilosicoli P43/6/78 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_007235315.1 1966228 D 1042417 CDS YP_007235316.1 431808418 14293964 1966556..1967626 1 NC_019908.1 COG0232 dGTP triphosphohydrolase; deoxyguanosinetriphosphate triphosphohydrolase 1967626 14293964 BPP43_09395 Brachyspira pilosicoli P43/6/78 deoxyguanosinetriphosphate triphosphohydrolase YP_007235316.1 1966556 D 1042417 CDS YP_007235317.1 431808419 14293965 1967710..1971456 1 NC_019908.1 COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; phosphoribosylformylglycinamidine synthase 1971456 14293965 BPP43_09400 Brachyspira pilosicoli P43/6/78 phosphoribosylformylglycinamidine synthase YP_007235317.1 1967710 D 1042417 CDS YP_007235318.1 431808420 14293966 complement(1971520..1973103) 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter substrate-binding protein 1973103 14293966 BPP43_09405 Brachyspira pilosicoli P43/6/78 oligopeptide ABC transporter substrate-binding protein YP_007235318.1 1971520 R 1042417 CDS YP_007235319.1 431808421 14293967 1973395..1973625 1 NC_019908.1 hypothetical protein 1973625 14293967 BPP43_09410 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235319.1 1973395 D 1042417 CDS YP_007235320.1 431808422 14293968 complement(1973670..1974992) 1 NC_019908.1 COG1030 Membrane-bound serine protease (ClpP class); membrane bound serine protease ClpP class 1974992 14293968 BPP43_09415 Brachyspira pilosicoli P43/6/78 membrane bound serine protease ClpP class YP_007235320.1 1973670 R 1042417 CDS YP_007235321.1 431808423 14293969 1975278..1976723 1 NC_019908.1 COG0531 Amino acid transporters; amino acid permease family protein 1976723 14293969 BPP43_09420 Brachyspira pilosicoli P43/6/78 amino acid permease family protein YP_007235321.1 1975278 D 1042417 CDS YP_007235322.1 431808424 14293970 1976739..1979891 1 NC_019908.1 COG3250 Beta-galactosidase/beta-glucuronidase; beta-galactosidase 1979891 14293970 BPP43_09425 Brachyspira pilosicoli P43/6/78 beta-galactosidase YP_007235322.1 1976739 D 1042417 CDS YP_007235323.1 431808425 14293971 1980247..1980735 1 NC_019908.1 COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; phosphoribosylaminoimidazole carboxylase catalytic subunit 1980735 14293971 BPP43_09430 Brachyspira pilosicoli P43/6/78 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_007235323.1 1980247 D 1042417 CDS YP_007235324.1 431808426 14293972 complement(1981242..1984409) 1 NC_019908.1 COG0841 Cation/multidrug efflux pump; acriflavin resistance protein 1984409 14293972 BPP43_09435 Brachyspira pilosicoli P43/6/78 acriflavin resistance protein YP_007235324.1 1981242 R 1042417 CDS YP_007235325.1 431808427 14293973 complement(1984451..1985953) 1 NC_019908.1 multidrug efflux outer membrane protein 1985953 14293973 BPP43_09440 Brachyspira pilosicoli P43/6/78 multidrug efflux outer membrane protein YP_007235325.1 1984451 R 1042417 CDS YP_007235326.1 431808428 14293974 1986603..1987157 1 NC_019908.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 1987157 14293974 BPP43_09445 Brachyspira pilosicoli P43/6/78 TetR family transcriptional regulator YP_007235326.1 1986603 D 1042417 CDS YP_007235327.1 431808429 14293975 1987272..1987967 1 NC_019908.1 COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase 1987967 14293975 BPP43_09450 Brachyspira pilosicoli P43/6/78 phosphoribosylaminoimidazolesuccinocarboxamide synthase YP_007235327.1 1987272 D 1042417 CDS YP_007235328.1 431808430 14293976 1988103..1988762 1 NC_019908.1 hypothetical protein 1988762 14293976 BPP43_09455 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235328.1 1988103 D 1042417 CDS YP_007235329.1 431808431 14293977 1988800..1989339 1 NC_019908.1 hypothetical protein 1989339 14293977 BPP43_09460 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235329.1 1988800 D 1042417 CDS YP_007235330.1 431808432 14293978 1989408..1990877 1 NC_019908.1 COG0260 Leucyl aminopeptidase; leucyl-aminopeptidase 1990877 14293978 BPP43_09465 Brachyspira pilosicoli P43/6/78 leucyl-aminopeptidase YP_007235330.1 1989408 D 1042417 CDS YP_007235331.1 431808433 14293979 1991073..1991813 1 NC_019908.1 COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptional regulator 1991813 14293979 BPP43_09470 Brachyspira pilosicoli P43/6/78 DeoR family transcriptional regulator YP_007235331.1 1991073 D 1042417 CDS YP_007235332.1 431808434 14293980 1991832..1992749 1 NC_019908.1 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); fructose-1-phosphate kinase 1992749 14293980 BPP43_09475 Brachyspira pilosicoli P43/6/78 fructose-1-phosphate kinase YP_007235332.1 1991832 D 1042417 CDS YP_007235333.1 431808435 14293981 1992782..1994656 1 NC_019908.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system fructose-specific transporter subunit IIABC 1994656 14293981 BPP43_09480 Brachyspira pilosicoli P43/6/78 PTS system fructose-specific transporter subunit IIABC YP_007235333.1 1992782 D 1042417 CDS YP_007235334.1 431808436 14293982 complement(1994903..1996555) 1 NC_019908.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase/permease MdlB 1996555 14293982 BPP43_09485 Brachyspira pilosicoli P43/6/78 multidrug ABC transporter ATPase/permease MdlB YP_007235334.1 1994903 R 1042417 CDS YP_007235335.1 431808437 14293983 complement(1996872..1998620) 1 NC_019908.1 COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components; cytochrome bd biosynthesis ABC transporter ATPase/permease 1998620 14293983 BPP43_09490 Brachyspira pilosicoli P43/6/78 cytochrome bd biosynthesis ABC transporter ATPase/permease YP_007235335.1 1996872 R 1042417 CDS YP_007235336.1 431808438 14293984 complement(1998645..1999202) 1 NC_019908.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 1999202 14293984 BPP43_09495 Brachyspira pilosicoli P43/6/78 TetR family transcriptional regulator YP_007235336.1 1998645 R 1042417 CDS YP_007235337.1 431808439 14293985 complement(1999251..1999805) 1 NC_019908.1 hypothetical protein 1999805 14293985 BPP43_09500 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235337.1 1999251 R 1042417 CDS YP_007235338.1 431808440 14293986 complement(1999873..2000268) 1 NC_019908.1 COG2832 Uncharacterized protein conserved in bacteria; hypothetical protein 2000268 14293986 BPP43_09505 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235338.1 1999873 R 1042417 CDS YP_007235339.1 431808441 14293987 complement(2000352..2001020) 1 NC_019908.1 hypothetical protein 2001020 14293987 BPP43_09510 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235339.1 2000352 R 1042417 CDS YP_007235340.1 431808442 14293988 2001167..2002423 1 NC_019908.1 COG0151 Phosphoribosylamine-glycine ligase; phosphoribosylamine glycine ligase 2002423 14293988 BPP43_09515 Brachyspira pilosicoli P43/6/78 phosphoribosylamine glycine ligase YP_007235340.1 2001167 D 1042417 CDS YP_007235341.1 431808443 14293989 complement(2003015..2003620) 1 NC_019908.1 hypothetical protein 2003620 14293989 BPP43_09520 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235341.1 2003015 R 1042417 CDS YP_007235342.1 431808444 14293990 complement(2003656..2004018) 1 NC_019908.1 COG2832 Uncharacterized protein conserved in bacteria; hypothetical protein 2004018 14293990 BPP43_09525 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235342.1 2003656 R 1042417 CDS YP_007235343.1 431808445 14293991 complement(2004015..2004422) 1 NC_019908.1 hypothetical protein 2004422 14293991 BPP43_09530 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235343.1 2004015 R 1042417 CDS YP_007235344.1 431808446 14293992 complement(2004554..2005222) 1 NC_019908.1 hypothetical protein 2005222 14293992 BPP43_09535 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235344.1 2004554 R 1042417 CDS YP_007235345.1 431808447 14293993 2005419..2007008 1 NC_019908.1 COG0018 Arginyl-tRNA synthetase; arginyl-tRNA synthetase ArgS 2007008 14293993 BPP43_09540 Brachyspira pilosicoli P43/6/78 arginyl-tRNA synthetase ArgS YP_007235345.1 2005419 D 1042417 CDS YP_007235346.1 431808448 14293994 2007244..2008392 1 NC_019908.1 COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; cell cycle protein MesJ 2008392 14293994 BPP43_09545 Brachyspira pilosicoli P43/6/78 cell cycle protein MesJ YP_007235346.1 2007244 D 1042417 CDS YP_007235347.1 431808449 14293995 complement(2008385..2009788) 1 NC_019908.1 COG2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 2009788 14293995 BPP43_09550 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235347.1 2008385 R 1042417 CDS YP_007235348.1 431808450 14293996 complement(2009772..2011340) 1 NC_019908.1 COG0714 MoxR-like ATPases; pyrrolo-quinoline quinone 2011340 14293996 BPP43_09555 Brachyspira pilosicoli P43/6/78 pyrrolo-quinoline quinone YP_007235348.1 2009772 R 1042417 CDS YP_007235349.1 431808451 14293997 2011558..2013495 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 2013495 14293997 BPP43_09560 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235349.1 2011558 D 1042417 CDS YP_007235350.1 431808452 14293998 2013527..2014249 1 NC_019908.1 hypothetical protein 2014249 14293998 BPP43_09565 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235350.1 2013527 D 1042417 CDS YP_007235351.1 431808453 14293999 2014251..2014880 1 NC_019908.1 COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division; methyltransferase GidB 2014880 14293999 BPP43_09570 Brachyspira pilosicoli P43/6/78 methyltransferase GidB YP_007235351.1 2014251 D 1042417 CDS YP_007235352.1 431808454 14294000 complement(2015492..2015905) 1 NC_019908.1 hypothetical protein 2015905 14294000 BPP43_09575 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235352.1 2015492 R 1042417 CDS YP_007235353.1 431808455 14294001 complement(2015972..2016625) 1 NC_019908.1 COG0176 Transaldolase; transaldolase 2016625 14294001 BPP43_09580 Brachyspira pilosicoli P43/6/78 transaldolase YP_007235353.1 2015972 R 1042417 CDS YP_007235354.1 431808456 14294002 2016769..2017248 1 NC_019908.1 hypothetical protein 2017248 14294002 BPP43_09585 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235354.1 2016769 D 1042417 CDS YP_007235355.1 431808457 14294003 2017261..2018244 1 NC_019908.1 COG0714 MoxR-like ATPases; ATPase 2018244 14294003 BPP43_09590 Brachyspira pilosicoli P43/6/78 ATPase YP_007235355.1 2017261 D 1042417 CDS YP_007235356.1 431808458 14294004 2018484..2020013 1 NC_019908.1 arylsulfate sulfotransferase 2020013 14294004 BPP43_09595 Brachyspira pilosicoli P43/6/78 arylsulfate sulfotransferase YP_007235356.1 2018484 D 1042417 CDS YP_007235357.1 431808459 14294005 complement(2020010..2021296) 1 NC_019908.1 hypothetical protein 2021296 14294005 BPP43_09600 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235357.1 2020010 R 1042417 CDS YP_007235358.1 431808460 14294006 2021631..2023253 1 NC_019908.1 COG1757 Na+/H+ antiporter; Na:H+ antiporter 2023253 14294006 BPP43_09605 Brachyspira pilosicoli P43/6/78 Na:H+ antiporter YP_007235358.1 2021631 D 1042417 CDS YP_007235359.1 431808461 14294007 2023498..2023728 1 NC_019908.1 COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system lactose/cellobiose-specific transporter subunit IIB SgaB 2023728 14294007 BPP43_09610 Brachyspira pilosicoli P43/6/78 PTS system lactose/cellobiose-specific transporter subunit IIB SgaB YP_007235359.1 2023498 D 1042417 CDS YP_007235360.1 431808462 14294008 2023765..2025036 1 NC_019908.1 COG3037 Uncharacterized protein conserved in bacteria; PTS system ascorbate-specific transporter subunit IIC 2025036 14294008 BPP43_09615 Brachyspira pilosicoli P43/6/78 PTS system ascorbate-specific transporter subunit IIC YP_007235360.1 2023765 D 1042417 CDS YP_007235361.1 431808463 14294009 2025087..2025896 1 NC_019908.1 COG3959 Transketolase, N-terminal subunit; transketolase 2025896 14294009 BPP43_09620 Brachyspira pilosicoli P43/6/78 transketolase YP_007235361.1 2025087 D 1042417 CDS YP_007235362.1 431808464 14294010 2025918..2026865 1 NC_019908.1 COG3958 Transketolase, C-terminal subunit; hypothetical protein 2026865 14294010 BPP43_09625 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235362.1 2025918 D 1042417 CDS YP_007235363.1 431808465 14294011 2026889..2027122 1 NC_019908.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS IIA-like nitrogen-regulatory protein PtsN 2027122 14294011 BPP43_09630 Brachyspira pilosicoli P43/6/78 PTS IIA-like nitrogen-regulatory protein PtsN YP_007235363.1 2026889 D 1042417 CDS YP_007235364.1 431808466 14294012 2027094..2027360 1 NC_019908.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS IIA-like nitrogen-regulatory protein PtsN 2027360 14294012 BPP43_09635 Brachyspira pilosicoli P43/6/78 PTS IIA-like nitrogen-regulatory protein PtsN YP_007235364.1 2027094 D 1042417 CDS YP_007235365.1 431808467 14294013 2027379..2027663 1 NC_019908.1 COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system lactose/cellobiose-specific transporter subunit IIB 2027663 14294013 BPP43_09640 Brachyspira pilosicoli P43/6/78 PTS system lactose/cellobiose-specific transporter subunit IIB YP_007235365.1 2027379 D 1042417 CDS YP_007235366.1 431808468 14294014 2027686..2028954 1 NC_019908.1 COG3037 Uncharacterized protein conserved in bacteria; PTS system ascorbate-specific transporter subunit IIC 2028954 14294014 BPP43_09645 Brachyspira pilosicoli P43/6/78 PTS system ascorbate-specific transporter subunit IIC YP_007235366.1 2027686 D 1042417 CDS YP_007235367.1 431808469 14294015 2029219..2031477 1 NC_019908.1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); 1A family penicillin-binding protein 2031477 14294015 BPP43_09650 Brachyspira pilosicoli P43/6/78 1A family penicillin-binding protein YP_007235367.1 2029219 D 1042417 CDS YP_007235368.1 431808470 14294016 complement(2031474..2032658) 1 NC_019908.1 COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase); bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 2032658 14294016 BPP43_09655 Brachyspira pilosicoli P43/6/78 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_007235368.1 2031474 R 1042417 CDS YP_007235369.1 431808471 14294017 complement(2032651..2033145) 1 NC_019908.1 hypothetical protein 2033145 14294017 BPP43_09660 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235369.1 2032651 R 1042417 CDS YP_007235370.1 431808472 14294018 complement(2033209..2033595) 1 NC_019908.1 hypothetical protein 2033595 14294018 BPP43_09665 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235370.1 2033209 R 1042417 CDS YP_007235371.1 431808473 14294019 complement(2033814..2034983) 1 NC_019908.1 COG1454 Alcohol dehydrogenase, class IV; alcohol dehydrogenase 2034983 14294019 BPP43_09670 Brachyspira pilosicoli P43/6/78 alcohol dehydrogenase YP_007235371.1 2033814 R 1042417 CDS YP_007235372.1 431808474 14294020 complement(2035204..2036163) 1 NC_019908.1 COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; UDP-galactose-lipooligosaccharide galactosyltransferase 2036163 14294020 BPP43_09675 Brachyspira pilosicoli P43/6/78 UDP-galactose-lipooligosaccharide galactosyltransferase YP_007235372.1 2035204 R 1042417 CDS YP_007235373.1 431808475 14294021 complement(2036183..2037175) 1 NC_019908.1 COG0392 Predicted integral membrane protein; hypothetical protein 2037175 14294021 BPP43_09680 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235373.1 2036183 R 1042417 CDS YP_007235374.1 431808476 14294022 complement(2037200..2038717) 1 NC_019908.1 hypothetical protein 2038717 14294022 BPP43_09685 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235374.1 2037200 R 1042417 CDS YP_007235375.1 431808477 14294023 complement(2038776..2039492) 1 NC_019908.1 hypothetical protein 2039492 14294023 BPP43_09690 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235375.1 2038776 R 1042417 CDS YP_007235376.1 431808478 14294024 2039737..2040846 1 NC_019908.1 COG1605 Chorismate mutase; prephenate dehydratase 2040846 14294024 BPP43_09695 Brachyspira pilosicoli P43/6/78 prephenate dehydratase YP_007235376.1 2039737 D 1042417 CDS YP_007235377.1 431808479 14294025 2040839..2041360 1 NC_019908.1 COG0703 Shikimate kinase; shikimate kinase 2041360 14294025 BPP43_09700 Brachyspira pilosicoli P43/6/78 shikimate kinase YP_007235377.1 2040839 D 1042417 CDS YP_007235378.1 431808480 14294026 complement(2041843..2043198) 1 NC_019908.1 COG0284 Orotidine-5'-phosphate decarboxylase; orotidine 5-phosphate decarboxylase orotate phosphoribosyltransferase 2043198 14294026 BPP43_09705 Brachyspira pilosicoli P43/6/78 orotidine 5-phosphate decarboxylase orotate phosphoribosyltransferase YP_007235378.1 2041843 R 1042417 CDS YP_007235379.1 431808481 14294027 complement(2043195..2044133) 1 NC_019908.1 COG0167 Dihydroorotate dehydrogenase; dihydroorotate dehydrogenase 2044133 14294027 BPP43_09710 Brachyspira pilosicoli P43/6/78 dihydroorotate dehydrogenase YP_007235379.1 2043195 R 1042417 CDS YP_007235380.1 431808482 14294028 complement(2044099..2044869) 1 NC_019908.1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; dihydroorotate dehydrogenase electron transfer subunit 2044869 14294028 BPP43_09715 Brachyspira pilosicoli P43/6/78 dihydroorotate dehydrogenase electron transfer subunit YP_007235380.1 2044099 R 1042417 CDS YP_007235381.1 431808483 14294029 complement(2044894..2045397) 1 NC_019908.1 COG2318 Uncharacterized protein conserved in bacteria; DinB-family protein 2045397 14294029 BPP43_09720 Brachyspira pilosicoli P43/6/78 DinB-family protein YP_007235381.1 2044894 R 1042417 CDS YP_007235382.1 431808484 14294030 complement(2045430..2045735) 1 NC_019908.1 DinB-family protein 2045735 14294030 BPP43_09725 Brachyspira pilosicoli P43/6/78 DinB-family protein YP_007235382.1 2045430 R 1042417 CDS YP_007235383.1 431808485 14294031 complement(2045824..2046285) 1 NC_019908.1 amidophosphoribosyltransferase 2046285 14294031 BPP43_09730 Brachyspira pilosicoli P43/6/78 amidophosphoribosyltransferase YP_007235383.1 2045824 R 1042417 CDS YP_007235384.1 431808486 14294032 complement(2046341..2046853) 1 NC_019908.1 hypothetical protein 2046853 14294032 BPP43_09735 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235384.1 2046341 R 1042417 CDS YP_007235385.1 431808487 14294033 2047093..2048298 1 NC_019908.1 hypothetical protein 2048298 14294033 BPP43_09740 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235385.1 2047093 D 1042417 CDS YP_007235386.1 431808488 14294035 2048656..2050065 1 NC_019908.1 COG0215 Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase 2050065 14294035 BPP43_09745 Brachyspira pilosicoli P43/6/78 cysteinyl-tRNA synthetase YP_007235386.1 2048656 D 1042417 CDS YP_007235387.1 431808489 14294036 2050040..2050933 1 NC_019908.1 COG3359 Predicted exonuclease; exonuclease 2050933 14294036 BPP43_09750 Brachyspira pilosicoli P43/6/78 exonuclease YP_007235387.1 2050040 D 1042417 CDS YP_007235388.1 431808490 14294037 complement(2050936..2052087) 1 NC_019908.1 COG1454 Alcohol dehydrogenase, class IV; alcohol dehydrogenase 2052087 14294037 BPP43_09755 Brachyspira pilosicoli P43/6/78 alcohol dehydrogenase YP_007235388.1 2050936 R 1042417 CDS YP_007235389.1 431808491 14294038 complement(2052557..2053660) 1 NC_019908.1 COG0714 MoxR-like ATPases; ATPase 2053660 14294038 BPP43_09760 Brachyspira pilosicoli P43/6/78 ATPase YP_007235389.1 2052557 R 1042417 CDS YP_007235390.1 431808492 14294039 2053845..2054207 1 NC_019908.1 hypothetical protein 2054207 14294039 BPP43_09765 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235390.1 2053845 D 1042417 CDS YP_007235391.1 431808493 14294040 complement(2054277..2054777) 1 NC_019908.1 hypothetical protein 2054777 14294040 BPP43_09770 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235391.1 2054277 R 1042417 CDS YP_007235392.1 431808494 14294041 complement(2054780..2055340) 1 NC_019908.1 COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); translation elongation factor P 2055340 14294041 BPP43_09775 Brachyspira pilosicoli P43/6/78 translation elongation factor P YP_007235392.1 2054780 R 1042417 CDS YP_007235393.1 431808495 14294042 complement(2055478..2056479) 1 NC_019908.1 hypothetical protein 2056479 14294042 BPP43_09780 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235393.1 2055478 R 1042417 CDS YP_007235394.1 431808496 14294043 2056711..2057127 1 NC_019908.1 COG0784 FOG: CheY-like receiver; chemotaxis response regulator CheY 2057127 14294043 BPP43_09785 Brachyspira pilosicoli P43/6/78 chemotaxis response regulator CheY YP_007235394.1 2056711 D 1042417 CDS YP_007235395.1 431808497 14294044 2057151..2057981 1 NC_019908.1 COG1352 Methylase of chemotaxis methyl-accepting proteins; chemotaxis protein methyltransferase 2057981 14294044 BPP43_09790 Brachyspira pilosicoli P43/6/78 chemotaxis protein methyltransferase YP_007235395.1 2057151 D 1042417 CDS YP_007235396.1 431808498 14294045 2057981..2058382 1 NC_019908.1 COG1664 Integral membrane protein CcmA involved in cell shape determination; hypothetical protein 2058382 14294045 BPP43_09795 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235396.1 2057981 D 1042417 CDS YP_007235397.1 431808499 14294046 2058391..2059329 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 2059329 14294046 BPP43_09800 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235397.1 2058391 D 1042417 CDS YP_007235398.1 431808500 14294047 2059347..2060360 1 NC_019908.1 COG1077 Actin-like ATPase involved in cell morphogenesis; rod shape-determining protein MreB 2060360 14294047 BPP43_09805 Brachyspira pilosicoli P43/6/78 rod shape-determining protein MreB YP_007235398.1 2059347 D 1042417 CDS YP_007235399.1 431808501 14294048 2060433..2061251 1 NC_019908.1 COG1792 Cell shape-determining protein; cell shape determining protein 2061251 14294048 BPP43_09810 Brachyspira pilosicoli P43/6/78 cell shape determining protein YP_007235399.1 2060433 D 1042417 CDS YP_007235400.1 431808502 14294049 2061248..2061787 1 NC_019908.1 rod shape determining protein MreD 2061787 14294049 BPP43_09815 Brachyspira pilosicoli P43/6/78 rod shape determining protein MreD YP_007235400.1 2061248 D 1042417 CDS YP_007235401.1 431808503 14294050 complement(2061927..2062934) 1 NC_019908.1 COG4956 Integral membrane protein (PIN domain superfamily); PIN domain-containing protein 2062934 14294050 BPP43_09820 Brachyspira pilosicoli P43/6/78 PIN domain-containing protein YP_007235401.1 2061927 R 1042417 CDS YP_007235402.1 431808504 14294051 complement(2063029..2063604) 1 NC_019908.1 COG1329 Transcriptional regulators, similar to M. xanthus CarD; CarD family transcriptional regulator 2063604 14294051 BPP43_09825 Brachyspira pilosicoli P43/6/78 CarD family transcriptional regulator YP_007235402.1 2063029 R 1042417 CDS YP_007235403.1 431808505 14294052 2063805..2064839 1 NC_019908.1 COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2064839 14294052 BPP43_09830 Brachyspira pilosicoli P43/6/78 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_007235403.1 2063805 D 1042417 CDS YP_007235404.1 431808506 14294053 2065065..2066078 1 NC_019908.1 COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; thiamine biosynthesis lipoprotein apbE precursor 2066078 14294053 BPP43_09835 Brachyspira pilosicoli P43/6/78 thiamine biosynthesis lipoprotein apbE precursor YP_007235404.1 2065065 D 1042417 CDS YP_007235405.1 431808507 14294054 2066520..2067437 1 NC_019908.1 hypothetical protein 2067437 14294054 BPP43_09840 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235405.1 2066520 D 1042417 CDS YP_007235406.1 431808508 14294055 complement(2067878..2068402) 1 NC_019908.1 COG0634 Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 2068402 14294055 BPP43_09845 Brachyspira pilosicoli P43/6/78 hypoxanthine-guanine phosphoribosyltransferase YP_007235406.1 2067878 R 1042417 CDS YP_007235407.1 431808509 14294056 complement(2068631..2069650) 1 NC_019908.1 COG2025 Electron transfer flavoprotein, alpha subunit; electron transfer flavoprotein subunit alpha 2069650 14294056 BPP43_09850 Brachyspira pilosicoli P43/6/78 electron transfer flavoprotein subunit alpha YP_007235407.1 2068631 R 1042417 CDS YP_007235408.1 431808510 14294057 complement(2069689..2070474) 1 NC_019908.1 COG2086 Electron transfer flavoprotein, beta subunit; electron transfer flavoprotein subunit beta 2070474 14294057 BPP43_09855 Brachyspira pilosicoli P43/6/78 electron transfer flavoprotein subunit beta YP_007235408.1 2069689 R 1042417 CDS YP_007235409.1 431808511 14294058 complement(2070512..2071657) 1 NC_019908.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 2071657 14294058 BPP43_09860 Brachyspira pilosicoli P43/6/78 acyl-CoA dehydrogenase YP_007235409.1 2070512 R 1042417 CDS YP_007235410.1 431808512 14294059 complement(2071785..2071976) 1 NC_019908.1 COG2030 Acyl dehydratase; MaoC domain-containing protein dehydratase 2071976 14294059 BPP43_09865 Brachyspira pilosicoli P43/6/78 MaoC domain-containing protein dehydratase YP_007235410.1 2071785 R 1042417 CDS YP_007235411.1 431808513 14294060 complement(2072000..2072113) 1 NC_019908.1 hypothetical protein 2072113 14294060 BPP43_09870 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235411.1 2072000 R 1042417 CDS YP_007235412.1 431808514 14294061 2072714..2073328 1 NC_019908.1 COG1390 Archaeal/vacuolar-type H+-ATPase subunit E; V-type ATP synthase subunit E 2073328 14294061 BPP43_09875 Brachyspira pilosicoli P43/6/78 V-type ATP synthase subunit E YP_007235412.1 2072714 D 1042417 CDS YP_007235413.1 431808515 14294062 2073340..2074173 1 NC_019908.1 hypothetical protein 2074173 14294062 BPP43_09880 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235413.1 2073340 D 1042417 CDS YP_007235414.1 431808516 14294063 2074199..2075962 1 NC_019908.1 COG1155 Archaeal/vacuolar-type H+-ATPase subunit A; V-type ATP synthase subunit A 2075962 14294063 BPP43_09885 Brachyspira pilosicoli P43/6/78 V-type ATP synthase subunit A YP_007235414.1 2074199 D 1042417 CDS YP_007235415.1 431808517 14294064 2075955..2077280 1 NC_019908.1 COG1156 Archaeal/vacuolar-type H+-ATPase subunit B; V-type ATP synthase subunit B 2077280 14294064 BPP43_09890 Brachyspira pilosicoli P43/6/78 V-type ATP synthase subunit B YP_007235415.1 2075955 D 1042417 CDS YP_007235416.1 431808518 14294065 2077896..2079755 1 NC_019908.1 COG1269 Archaeal/vacuolar-type H+-ATPase subunit I; V-type ATP synthase subunit I 2079755 14294065 BPP43_09905 Brachyspira pilosicoli P43/6/78 V-type ATP synthase subunit I YP_007235416.1 2077896 D 1042417 CDS YP_007235417.1 431808519 14294066 2079824..2080291 1 NC_019908.1 COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K; V-type ATP synthase subunit K 2080291 14294066 BPP43_09910 Brachyspira pilosicoli P43/6/78 V-type ATP synthase subunit K YP_007235417.1 2079824 D 1042417 CDS YP_007235418.1 431808520 14294067 2080723..2081097 1 NC_019908.1 COG0048 Ribosomal protein S12; 30S ribosomal protein S12 2081097 14294067 BPP43_09915 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S12 YP_007235418.1 2080723 D 1042417 CDS YP_007235419.1 431808521 14294068 2081112..2081582 1 NC_019908.1 COG0049 Ribosomal protein S7; 30S ribosomal protein S7 2081582 14294068 BPP43_09920 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S7 YP_007235419.1 2081112 D 1042417 CDS YP_007235420.1 431808522 14294069 2081603..2083684 1 NC_019908.1 COG0480 Translation elongation factors (GTPases); elongation factor G 2083684 14294069 BPP43_09925 Brachyspira pilosicoli P43/6/78 elongation factor G YP_007235420.1 2081603 D 1042417 CDS YP_007235421.1 431808523 14294070 2083751..2084977 1 NC_019908.1 COG0050 GTPases - translation elongation factors; elongation factor Tu 2084977 14294070 BPP43_09930 Brachyspira pilosicoli P43/6/78 elongation factor Tu YP_007235421.1 2083751 D 1042417 CDS YP_007235422.1 431808524 14294071 2085059..2085364 1 NC_019908.1 COG0051 Ribosomal protein S10; 30S ribosomal protein S10 2085364 14294071 BPP43_09935 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S10 YP_007235422.1 2085059 D 1042417 CDS YP_007235423.1 431808525 14294072 2085490..2086146 1 NC_019908.1 COG0087 Ribosomal protein L3; 50S ribosomal protein L3 2086146 14294072 BPP43_09940 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L3 YP_007235423.1 2085490 D 1042417 CDS YP_007235424.1 431808526 14294073 2086165..2086812 1 NC_019908.1 COG0088 Ribosomal protein L4; 50S ribosomal protein L4 2086812 14294073 BPP43_09945 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L4 YP_007235424.1 2086165 D 1042417 CDS YP_007235425.1 431808527 14294074 2086818..2087117 1 NC_019908.1 COG0089 Ribosomal protein L23; 50S ribosomal protein L23 2087117 14294074 BPP43_09950 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L23 YP_007235425.1 2086818 D 1042417 CDS YP_007235426.1 431808528 14294075 2087132..2087968 1 NC_019908.1 COG0090 Ribosomal protein L2; 50S ribosomal protein L2 2087968 rplB 14294075 rplB Brachyspira pilosicoli P43/6/78 50S ribosomal protein L2 YP_007235426.1 2087132 D 1042417 CDS YP_007235427.1 431808529 14294076 2087968..2088237 1 NC_019908.1 COG0185 Ribosomal protein S19; 30S ribosomal protein S19 2088237 14294076 BPP43_09960 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S19 YP_007235427.1 2087968 D 1042417 CDS YP_007235428.1 431808530 14294077 2088249..2088653 1 NC_019908.1 COG0091 Ribosomal protein L22; 50S ribosomal protein L22 2088653 14294077 BPP43_09965 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L22 YP_007235428.1 2088249 D 1042417 CDS YP_007235429.1 431808531 14294078 2088657..2089394 1 NC_019908.1 COG0092 Ribosomal protein S3; 30S ribosomal protein S3 2089394 14294078 BPP43_09970 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S3 YP_007235429.1 2088657 D 1042417 CDS YP_007235430.1 431808532 14294079 2089394..2089807 1 NC_019908.1 COG0197 Ribosomal protein L16/L10E; 50S ribosomal protein L16 2089807 rplP 14294079 rplP Brachyspira pilosicoli P43/6/78 50S ribosomal protein L16 YP_007235430.1 2089394 D 1042417 CDS YP_007235431.1 431808533 14294080 2089807..2090013 1 NC_019908.1 COG0255 Ribosomal protein L29; 50S ribosomal protein L29 2090013 14294080 BPP43_09980 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L29 YP_007235431.1 2089807 D 1042417 CDS YP_007235432.1 431808534 14294081 2090028..2090390 1 NC_019908.1 COG0186 Ribosomal protein S17; 30S ribosomal protein S17 2090390 14294081 BPP43_09985 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S17 YP_007235432.1 2090028 D 1042417 CDS YP_007235433.1 431808535 14294082 2090396..2090563 1 NC_019908.1 COG0093 Ribosomal protein L14; 50S ribosomal protein L14 2090563 14294082 BPP43_09990 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L14 YP_007235433.1 2090396 D 1042417 CDS YP_007235434.1 431808536 14294083 2090768..2091109 1 NC_019908.1 COG0198 Ribosomal protein L24; 50S ribosomal protein L24 2091109 14294083 BPP43_09995 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L24 YP_007235434.1 2090768 D 1042417 CDS YP_007235435.1 431808537 14294084 2091126..2091689 1 NC_019908.1 COG0094 Ribosomal protein L5; 50S ribosomal protein L5 2091689 14294084 BPP43_10000 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L5 YP_007235435.1 2091126 D 1042417 CDS YP_007235436.1 431808538 14294085 2091689..2091874 1 NC_019908.1 COG0199 Ribosomal protein S14; 30S ribosomal protein S14 2091874 14294085 BPP43_10005 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S14 YP_007235436.1 2091689 D 1042417 CDS YP_007235437.1 431808539 14294086 2091893..2092294 1 NC_019908.1 COG0096 Ribosomal protein S8; 30S ribosomal protein S8 2092294 14294086 BPP43_10010 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S8 YP_007235437.1 2091893 D 1042417 CDS YP_007235438.1 431808540 14294087 2092320..2092892 1 NC_019908.1 COG0097 Ribosomal protein L6P/L9E; 50S ribosomal protein L6 2092892 14294087 BPP43_10015 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L6 YP_007235438.1 2092320 D 1042417 CDS YP_007235439.1 431808541 14294088 2092905..2093261 1 NC_019908.1 COG0256 Ribosomal protein L18; 50S ribosomal protein L18 2093261 14294088 BPP43_10020 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L18 YP_007235439.1 2092905 D 1042417 CDS YP_007235440.1 431808542 14294089 2093273..2093785 1 NC_019908.1 COG0098 Ribosomal protein S5; 30S ribosomal protein S5 2093785 14294089 BPP43_10025 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S5 YP_007235440.1 2093273 D 1042417 CDS YP_007235441.1 431808543 14294090 2093785..2093964 1 NC_019908.1 COG1841 Ribosomal protein L30/L7E; 50S ribosomal protein L30 2093964 14294090 BPP43_10030 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L30 YP_007235441.1 2093785 D 1042417 CDS YP_007235442.1 431808544 14294091 2093975..2094454 1 NC_019908.1 COG0200 Ribosomal protein L15; 50S ribosomal protein L15 2094454 14294091 BPP43_10035 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L15 YP_007235442.1 2093975 D 1042417 CDS YP_007235443.1 431808545 14294092 2094467..2095807 1 NC_019908.1 COG0201 Preprotein translocase subunit SecY; preprotein translocase SecY 2095807 14294092 BPP43_10040 Brachyspira pilosicoli P43/6/78 preprotein translocase SecY YP_007235443.1 2094467 D 1042417 CDS YP_007235444.1 431808546 14294093 2095813..2096031 1 NC_019908.1 COG0361 Translation initiation factor 1 (IF-1); translation initiation factor IF-1 2096031 14294093 BPP43_10045 Brachyspira pilosicoli P43/6/78 translation initiation factor IF-1 YP_007235444.1 2095813 D 1042417 CDS YP_007235445.1 431808547 14294094 2096052..2096168 1 NC_019908.1 COG0257 Ribosomal protein L36; 50S ribosomal protein L36 2096168 14294094 BPP43_10050 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L36 YP_007235445.1 2096052 D 1042417 CDS YP_007235446.1 431808548 14294095 2096191..2096580 1 NC_019908.1 COG0099 Ribosomal protein S13; 30S ribosomal protein S13 2096580 14294095 BPP43_10055 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S13 YP_007235446.1 2096191 D 1042417 CDS YP_007235447.1 431808549 14294096 2096603..2097013 1 NC_019908.1 COG0100 Ribosomal protein S11; 30S ribosomal protein S11 2097013 14294096 BPP43_10060 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S11 YP_007235447.1 2096603 D 1042417 CDS YP_007235448.1 431808550 14294097 2097035..2097661 1 NC_019908.1 COG0522 Ribosomal protein S4 and related proteins; 30S ribosomal protein S4 2097661 14294097 BPP43_10065 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S4 YP_007235448.1 2097035 D 1042417 CDS YP_007235449.1 431808551 14294098 2097692..2098669 1 NC_019908.1 COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA directed RNA polymerase subunit alpha 2098669 14294098 BPP43_10070 Brachyspira pilosicoli P43/6/78 DNA directed RNA polymerase subunit alpha YP_007235449.1 2097692 D 1042417 CDS YP_007235450.1 431808552 14294099 2098688..2099077 1 NC_019908.1 COG0203 Ribosomal protein L17; 50S ribosomal protein L17 2099077 14294099 BPP43_10075 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L17 YP_007235450.1 2098688 D 1042417 CDS YP_007235451.1 431808553 14294100 2099208..2100677 1 NC_019908.1 COG1158 Transcription termination factor; transcription termination factor Rho 2100677 14294100 BPP43_10080 Brachyspira pilosicoli P43/6/78 transcription termination factor Rho YP_007235451.1 2099208 D 1042417 CDS YP_007235452.1 431808554 14294101 2100691..2101275 1 NC_019908.1 COG2840 Uncharacterized protein conserved in bacteria; Smr domain-containing protein 2101275 14294101 BPP43_10085 Brachyspira pilosicoli P43/6/78 Smr domain-containing protein YP_007235452.1 2100691 D 1042417 CDS YP_007235453.1 431808555 14294102 2101961..2103526 1 NC_019908.1 COG2812 DNA polymerase III, gamma/tau subunits; DNA polymerase III subunits gamma and tau 2103526 14294102 BPP43_10090 Brachyspira pilosicoli P43/6/78 DNA polymerase III subunits gamma and tau YP_007235453.1 2101961 D 1042417 CDS YP_007235454.1 431808556 14294103 complement(2103594..2104178) 1 NC_019908.1 hypothetical protein 2104178 14294103 BPP43_10095 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235454.1 2103594 R 1042417 CDS YP_007235455.1 431808557 14294104 complement(2104376..2105020) 1 NC_019908.1 hypothetical protein 2105020 14294104 BPP43_10100 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235455.1 2104376 R 1042417 CDS YP_007235456.1 431808558 14294105 2105328..2106872 1 NC_019908.1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); acetyl-CoA carboxylase subunit alpha 2106872 14294105 BPP43_10105 Brachyspira pilosicoli P43/6/78 acetyl-CoA carboxylase subunit alpha YP_007235456.1 2105328 D 1042417 CDS YP_007235457.1 431808559 14294106 2106911..2107216 1 NC_019908.1 sodium pump decarboxylase subunit gamma 2107216 14294106 BPP43_10110 Brachyspira pilosicoli P43/6/78 sodium pump decarboxylase subunit gamma YP_007235457.1 2106911 D 1042417 CDS YP_007235458.1 431808560 14294107 2107254..2107673 1 NC_019908.1 COG0511 Biotin carboxyl carrier protein; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 2107673 14294107 BPP43_10115 Brachyspira pilosicoli P43/6/78 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_007235458.1 2107254 D 1042417 CDS YP_007235459.1 431808561 14294108 2107694..2108821 1 NC_019908.1 COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; Na-transporting methylmalonyl CoA oxaloacetate decarboxylase subunit beta 2108821 14294108 BPP43_10120 Brachyspira pilosicoli P43/6/78 Na-transporting methylmalonyl CoA oxaloacetate decarboxylase subunit beta YP_007235459.1 2107694 D 1042417 CDS YP_007235460.1 431808562 14294109 complement(2108891..2109706) 1 NC_019908.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; polar amino acid ABC transporter substrate-binding protein 2109706 14294109 BPP43_10125 Brachyspira pilosicoli P43/6/78 polar amino acid ABC transporter substrate-binding protein YP_007235460.1 2108891 R 1042417 CDS YP_007235461.1 431808563 14294110 complement(2109926..2110741) 1 NC_019908.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; polar amino acid ABC transporter substrate-binding protein 2110741 14294110 BPP43_10130 Brachyspira pilosicoli P43/6/78 polar amino acid ABC transporter substrate-binding protein YP_007235461.1 2109926 R 1042417 CDS YP_007235462.1 431808564 14294111 complement(2111025..2111831) 1 NC_019908.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; polar amino acid ABC transporter substrate-binding protein 2111831 14294111 BPP43_10135 Brachyspira pilosicoli P43/6/78 polar amino acid ABC transporter substrate-binding protein YP_007235462.1 2111025 R 1042417 CDS YP_007235463.1 431808565 14294112 complement(2112125..2112946) 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 2112946 14294112 BPP43_10140 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235463.1 2112125 R 1042417 CDS YP_007235464.1 431808566 14294113 complement(2113023..2114150) 1 NC_019908.1 COG0343 Queuine/archaeosine tRNA-ribosyltransferase; queuine tR-ribosyltransferase 2114150 14294113 BPP43_10145 Brachyspira pilosicoli P43/6/78 queuine tR-ribosyltransferase YP_007235464.1 2113023 R 1042417 CDS YP_007235465.1 431808567 14294114 complement(2115283..2116029) 1 NC_019908.1 COG0588 Phosphoglycerate mutase 1; phosphoglycerate mutase 2116029 14294114 BPP43_10160 Brachyspira pilosicoli P43/6/78 phosphoglycerate mutase YP_007235465.1 2115283 R 1042417 CDS YP_007235466.1 431808568 14294116 2116335..2116598 1 NC_019908.1 COG0268 Ribosomal protein S20; 30S ribosomal protein S20 2116598 14294116 BPP43_10165 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S20 YP_007235466.1 2116335 D 1042417 CDS YP_007235467.1 431808569 14294117 2116743..2117180 1 NC_019908.1 hypothetical protein 2117180 14294117 BPP43_10170 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235467.1 2116743 D 1042417 CDS YP_007235468.1 431808570 14294118 2120568..2122298 1 NC_019908.1 COG0557 Exoribonuclease R; exoribonuclease R 2122298 14294118 BPP43_10185 Brachyspira pilosicoli P43/6/78 exoribonuclease R YP_007235468.1 2120568 D 1042417 CDS YP_007235469.1 431808571 14294119 complement(2122368..2123384) 1 NC_019908.1 hypothetical protein 2123384 14294119 BPP43_10190 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235469.1 2122368 R 1042417 CDS YP_007235470.1 431808572 14294120 complement(2123430..2124428) 1 NC_019908.1 surface antigen BspA like protein 2124428 14294120 BPP43_10195 Brachyspira pilosicoli P43/6/78 surface antigen BspA like protein YP_007235470.1 2123430 R 1042417 CDS YP_007235471.1 431808573 14294121 complement(2124731..2126425) 1 NC_019908.1 COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; pyridine nucleotide-disulfide oxidoreductase family protein 2126425 14294121 BPP43_10200 Brachyspira pilosicoli P43/6/78 pyridine nucleotide-disulfide oxidoreductase family protein YP_007235471.1 2124731 R 1042417 CDS YP_007235472.1 431808574 14294122 2126721..2127665 1 NC_019908.1 COG2358 TRAP-type uncharacterized transport system, periplasmic component; TRAP transporter solute receptor 2127665 14294122 BPP43_10205 Brachyspira pilosicoli P43/6/78 TRAP transporter solute receptor YP_007235472.1 2126721 D 1042417 CDS YP_007235473.1 431808575 14294123 2127686..2128174 1 NC_019908.1 COG4729 Uncharacterized conserved protein; hypothetical protein 2128174 14294123 BPP43_10210 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235473.1 2127686 D 1042417 CDS YP_007235474.1 431808576 14294124 2128171..2130141 1 NC_019908.1 COG4666 TRAP-type uncharacterized transport system, fused permease components; TRAP transporter 4TM/12TM fusion protein 2130141 14294124 BPP43_10215 Brachyspira pilosicoli P43/6/78 TRAP transporter 4TM/12TM fusion protein YP_007235474.1 2128171 D 1042417 CDS YP_007235475.1 431808577 14294125 2130552..2131688 1 NC_019908.1 variable surface protein VspD 2131688 14294125 BPP43_10220 Brachyspira pilosicoli P43/6/78 variable surface protein VspD YP_007235475.1 2130552 D 1042417 CDS YP_007235476.1 431808578 14294126 complement(2131955..2133238) 1 NC_019908.1 COG0104 Adenylosuccinate synthase; adenylosuccinate synthase 2133238 14294126 BPP43_10225 Brachyspira pilosicoli P43/6/78 adenylosuccinate synthase YP_007235476.1 2131955 R 1042417 CDS YP_007235477.1 431808579 14294127 complement(2133388..2134821) 1 NC_019908.1 COG0863 DNA modification methylase; adenine-specific DNA methylase 2134821 14294127 BPP43_10230 Brachyspira pilosicoli P43/6/78 adenine-specific DNA methylase YP_007235477.1 2133388 R 1042417 CDS YP_007235478.1 431808580 14294128 complement(2134943..2137492) 1 NC_019908.1 COG0466 ATP-dependent Lon protease, bacterial type; ATP-dependent protease La 2137492 14294128 BPP43_10235 Brachyspira pilosicoli P43/6/78 ATP-dependent protease La YP_007235478.1 2134943 R 1042417 CDS YP_007235479.1 431808581 14294129 complement(2137693..2138826) 1 NC_019908.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aminotransferase A 2138826 14294129 BPP43_10240 Brachyspira pilosicoli P43/6/78 aminotransferase A YP_007235479.1 2137693 R 1042417 CDS YP_007235480.1 431808582 14294130 complement(2138925..2139194) 1 NC_019908.1 hypothetical protein 2139194 14294130 BPP43_10245 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235480.1 2138925 R 1042417 CDS YP_007235481.1 431808583 14294131 complement(2139178..2139270) 1 NC_019908.1 hypothetical protein 2139270 14294131 BPP43_10250 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235481.1 2139178 R 1042417 CDS YP_007235482.1 431808584 14294132 2141441..2141668 1 NC_019908.1 hypothetical protein 2141668 14294132 BPP43_10265 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235482.1 2141441 D 1042417 CDS YP_007235483.1 431808585 14294134 2145263..2145493 1 NC_019908.1 hypothetical protein 2145493 14294134 BPP43_10270 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235483.1 2145263 D 1042417 CDS YP_007235484.1 431808586 14294135 2145545..2145841 1 NC_019908.1 hypothetical protein 2145841 14294135 BPP43_10275 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235484.1 2145545 D 1042417 CDS YP_007235485.1 431808587 14294136 complement(2145849..2146838) 1 NC_019908.1 COG1609 Transcriptional regulators; sucrose operon repressor 2146838 14294136 BPP43_10280 Brachyspira pilosicoli P43/6/78 sucrose operon repressor YP_007235485.1 2145849 R 1042417 CDS YP_007235486.1 431808588 14294137 2147003..2148424 1 NC_019908.1 COG1264 Phosphotransferase system IIB components; PTS system transporter subunit IIABC 2148424 14294137 BPP43_10285 Brachyspira pilosicoli P43/6/78 PTS system transporter subunit IIABC YP_007235486.1 2147003 D 1042417 CDS YP_007235487.1 431808589 14294138 2148451..2149926 1 NC_019908.1 COG1621 Beta-fructosidases (levanase/invertase); beta fructosidase levanase invertase 2149926 14294138 BPP43_10290 Brachyspira pilosicoli P43/6/78 beta fructosidase levanase invertase YP_007235487.1 2148451 D 1042417 CDS YP_007235488.1 431808590 14294139 2150138..2150665 1 NC_019908.1 COG1516 Flagellin-specific chaperone FliS; flagellar protein FliS 2150665 14294139 BPP43_10295 Brachyspira pilosicoli P43/6/78 flagellar protein FliS YP_007235488.1 2150138 D 1042417 CDS YP_007235489.1 431808591 14294140 2150668..2151408 1 NC_019908.1 pullulanase family protein 2151408 14294140 BPP43_10300 Brachyspira pilosicoli P43/6/78 pullulanase family protein YP_007235489.1 2150668 D 1042417 CDS YP_007235490.1 431808592 14294141 complement(2151466..2152281) 1 NC_019908.1 COG1331 Highly conserved protein containing a thioredoxin domain; thiol-disulfide interchange like protein 2152281 14294141 BPP43_10305 Brachyspira pilosicoli P43/6/78 thiol-disulfide interchange like protein YP_007235490.1 2151466 R 1042417 CDS YP_007235491.1 431808593 14294142 complement(2152387..2152728) 1 NC_019908.1 COG0238 Ribosomal protein S18; 30S ribosomal protein S18 2152728 14294142 BPP43_10310 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S18 YP_007235491.1 2152387 R 1042417 CDS YP_007235492.1 431808594 14294143 complement(2152753..2153190) 1 NC_019908.1 COG0629 Single-stranded DNA-binding protein; ssDNA-binding protein 2153190 14294143 BPP43_10315 Brachyspira pilosicoli P43/6/78 ssDNA-binding protein YP_007235492.1 2152753 R 1042417 CDS YP_007235493.1 431808595 14294144 complement(2153222..2153554) 1 NC_019908.1 COG0360 Ribosomal protein S6; 30S ribosomal protein S6 2153554 14294144 BPP43_10320 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S6 YP_007235493.1 2153222 R 1042417 CDS YP_007235494.1 431808596 14294145 2153728..2155800 1 NC_019908.1 COG1200 RecG-like helicase; ATP-dependent DNA helicase RecG 2155800 14294145 BPP43_10325 Brachyspira pilosicoli P43/6/78 ATP-dependent DNA helicase RecG YP_007235494.1 2153728 D 1042417 CDS YP_007235495.1 431808597 14294146 complement(2156337..2156549) 1 NC_019908.1 COG1040 Predicted amidophosphoribosyltransferases; phosphoribosyltransferace 2156549 14294146 BPP43_10330 Brachyspira pilosicoli P43/6/78 phosphoribosyltransferace YP_007235495.1 2156337 R 1042417 CDS YP_007235496.1 431808598 14294147 complement(2156575..2157069) 1 NC_019908.1 COG1040 Predicted amidophosphoribosyltransferases; phosphoribosyltransferace 2157069 14294147 BPP43_10335 Brachyspira pilosicoli P43/6/78 phosphoribosyltransferace YP_007235496.1 2156575 R 1042417 CDS YP_007235497.1 431808599 14294148 complement(2157062..2157823) 1 NC_019908.1 COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; 3-deoxy-manno-octulosonate cytidylyltransferase 2157823 14294148 BPP43_10340 Brachyspira pilosicoli P43/6/78 3-deoxy-manno-octulosonate cytidylyltransferase YP_007235497.1 2157062 R 1042417 CDS YP_007235498.1 431808600 14294149 complement(2157825..2158310) 1 NC_019908.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system D-fructose-specific transporter subunit IIBC 2158310 14294149 BPP43_10345 Brachyspira pilosicoli P43/6/78 PTS system D-fructose-specific transporter subunit IIBC YP_007235498.1 2157825 R 1042417 CDS YP_007235499.1 431808601 14294150 complement(2158327..2158722) 1 NC_019908.1 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; hypothetical protein 2158722 14294150 BPP43_10350 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235499.1 2158327 R 1042417 CDS YP_007235500.1 431808602 14294154 2159221..2159925 1 NC_019908.1 hypothetical protein 2159925 14294154 BPP43_10355 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235500.1 2159221 D 1042417 CDS YP_007235501.1 431808603 14294156 complement(2160097..2160519) 1 NC_019908.1 COG3339 Uncharacterized conserved protein; hypothetical protein 2160519 14294156 BPP43_10360 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235501.1 2160097 R 1042417 CDS YP_007235502.1 431808604 14294157 complement(2160580..2162193) 1 NC_019908.1 hypothetical protein 2162193 14294157 BPP43_10365 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235502.1 2160580 R 1042417 CDS YP_007235503.1 431808605 14294158 2162412..2163767 1 NC_019908.1 COG0527 Aspartokinases; aspartate kinase 2163767 14294158 BPP43_10370 Brachyspira pilosicoli P43/6/78 aspartate kinase YP_007235503.1 2162412 D 1042417 CDS YP_007235504.1 431808606 14294159 2164131..2164559 1 NC_019908.1 hypothetical protein 2164559 14294159 BPP43_10375 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235504.1 2164131 D 1042417 CDS YP_007235505.1 431808607 14294160 2164648..2165760 1 NC_019908.1 COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; monogalactosyldiacylglycerol synthase 2165760 14294160 BPP43_10380 Brachyspira pilosicoli P43/6/78 monogalactosyldiacylglycerol synthase YP_007235505.1 2164648 D 1042417 CDS YP_007235506.1 431808608 14294161 complement(2165757..2166176) 1 NC_019908.1 hypothetical protein 2166176 14294161 BPP43_10385 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235506.1 2165757 R 1042417 CDS YP_007235507.1 431808609 14294162 complement(2166252..2168093) 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein B 2168093 14294162 BPP43_10390 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis protein B YP_007235507.1 2166252 R 1042417 CDS YP_007235508.1 431808610 14294163 2168413..2169381 1 NC_019908.1 COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; pyruvate oxireductase 2169381 14294163 BPP43_10395 Brachyspira pilosicoli P43/6/78 pyruvate oxireductase YP_007235508.1 2168413 D 1042417 CDS YP_007235509.1 431808611 14294164 2169396..2171660 1 NC_019908.1 COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; pyruvate ferredoxin oxidoreductase subunit alpha 2171660 14294164 BPP43_10400 Brachyspira pilosicoli P43/6/78 pyruvate ferredoxin oxidoreductase subunit alpha YP_007235509.1 2169396 D 1042417 CDS YP_007235510.1 431808612 14294165 2172150..2174099 1 NC_019908.1 COG0143 Methionyl-tRNA synthetase; methionyl-tRNA synthetase 2174099 14294165 BPP43_10405 Brachyspira pilosicoli P43/6/78 methionyl-tRNA synthetase YP_007235510.1 2172150 D 1042417 CDS YP_007235511.1 431808613 14294166 2174116..2174886 1 NC_019908.1 COG1589 Cell division septal protein; cell division protein 2174886 14294166 BPP43_10410 Brachyspira pilosicoli P43/6/78 cell division protein YP_007235511.1 2174116 D 1042417 CDS YP_007235512.1 431808614 14294167 2174911..2175315 1 NC_019908.1 hypothetical protein 2175315 14294167 BPP43_10415 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235512.1 2174911 D 1042417 CDS YP_007235513.1 431808615 14294168 complement(2176213..2177154) 1 NC_019908.1 COG1275 Tellurite resistance protein and related permeases; C4-dicarboxylate transporter/malic acid transport protein 2177154 14294168 BPP43_10420 Brachyspira pilosicoli P43/6/78 C4-dicarboxylate transporter/malic acid transport protein YP_007235513.1 2176213 R 1042417 CDS YP_007235514.1 431808616 14294169 2177305..2177643 1 NC_019908.1 hypothetical protein 2177643 14294169 BPP43_10425 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235514.1 2177305 D 1042417 CDS YP_007235515.1 431808617 14294170 complement(2178505..2179659) 1 NC_019908.1 COG3055 Uncharacterized protein conserved in bacteria; lipoprotein 2179659 14294170 BPP43_10440 Brachyspira pilosicoli P43/6/78 lipoprotein YP_007235515.1 2178505 R 1042417 CDS YP_007235516.1 431808618 14294171 complement(2179698..2181179) 1 NC_019908.1 COG0591 Na+/proline symporter; solute:Na(+) symporter 2181179 14294171 BPP43_10445 Brachyspira pilosicoli P43/6/78 solute:Na(+) symporter YP_007235516.1 2179698 R 1042417 CDS YP_007235517.1 431808619 14294172 complement(2181300..2181764) 1 NC_019908.1 COG2731 Beta-galactosidase, beta subunit; hypothetical protein 2181764 14294172 BPP43_10450 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235517.1 2181300 R 1042417 CDS YP_007235518.1 431808620 14294173 complement(2181838..2182734) 1 NC_019908.1 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; N-acetylneuraminate lyase 2182734 14294173 BPP43_10455 Brachyspira pilosicoli P43/6/78 N-acetylneuraminate lyase YP_007235518.1 2181838 R 1042417 CDS YP_007235519.1 431808621 14294174 2183215..2184522 1 NC_019908.1 COG4409 Neuraminidase (sialidase); neuraminidase (sialidase)-like protein 2184522 14294174 BPP43_10460 Brachyspira pilosicoli P43/6/78 neuraminidase (sialidase)-like protein YP_007235519.1 2183215 D 1042417 CDS YP_007235520.1 431808622 14294175 2184611..2185882 1 NC_019908.1 variable surface protein VspH 2185882 14294175 BPP43_10465 Brachyspira pilosicoli P43/6/78 variable surface protein VspH YP_007235520.1 2184611 D 1042417 CDS YP_007235521.1 431808623 14294176 complement(2185956..2186321) 1 NC_019908.1 COG3339 Uncharacterized conserved protein; hypothetical protein 2186321 14294176 BPP43_10470 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235521.1 2185956 R 1042417 CDS YP_007235522.1 431808624 14294177 2186474..2187655 1 NC_019908.1 COG2942 N-acyl-D-glucosamine 2-epimerase; N-acyl-D-glucosamine-2-epimerase 2187655 14294177 BPP43_10475 Brachyspira pilosicoli P43/6/78 N-acyl-D-glucosamine-2-epimerase YP_007235522.1 2186474 D 1042417 CDS YP_007235523.1 431808625 14294178 2187826..2190603 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 2190603 14294178 BPP43_10480 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235523.1 2187826 D 1042417 CDS YP_007235524.1 431808626 14294179 2190756..2191766 1 NC_019908.1 COG0778 Nitroreductase; streptolysin associated protein SagB 2191766 14294179 BPP43_10485 Brachyspira pilosicoli P43/6/78 streptolysin associated protein SagB YP_007235524.1 2190756 D 1042417 CDS YP_007235525.1 431808627 14294180 2191800..2192885 1 NC_019908.1 streptolysin associated protein SagC 2192885 14294180 BPP43_10490 Brachyspira pilosicoli P43/6/78 streptolysin associated protein SagC YP_007235525.1 2191800 D 1042417 CDS YP_007235526.1 431808628 14294181 2192941..2194281 1 NC_019908.1 streptolysin associated protein SagD 2194281 14294181 BPP43_10495 Brachyspira pilosicoli P43/6/78 streptolysin associated protein SagD YP_007235526.1 2192941 D 1042417 CDS YP_007235527.1 431808629 14294182 2194905..2195645 1 NC_019908.1 hypothetical protein 2195645 14294182 BPP43_10510 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235527.1 2194905 D 1042417 CDS YP_007235528.1 431808630 14294183 2195985..2196680 1 NC_019908.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 2196680 14294183 BPP43_10515 Brachyspira pilosicoli P43/6/78 ABC transporter-like protein YP_007235528.1 2195985 D 1042417 CDS YP_007235529.1 431808631 14294184 2196858..2197574 1 NC_019908.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter inner membrane protein 2197574 14294184 BPP43_10520 Brachyspira pilosicoli P43/6/78 ABC transporter inner membrane protein YP_007235529.1 2196858 D 1042417 CDS YP_007235530.1 431808632 14294185 2197998..2198327 1 NC_019908.1 COG1695 Predicted transcriptional regulators; transcriptional regulator 2198327 14294185 BPP43_10525 Brachyspira pilosicoli P43/6/78 transcriptional regulator YP_007235530.1 2197998 D 1042417 CDS YP_007235531.1 431808633 14294186 2198354..2199004 1 NC_019908.1 hypothetical protein 2199004 14294186 BPP43_10530 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235531.1 2198354 D 1042417 CDS YP_007235532.1 431808634 14294187 2199007..2199663 1 NC_019908.1 hypothetical protein 2199663 14294187 BPP43_10535 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235532.1 2199007 D 1042417 CDS YP_007235533.1 431808635 14294188 2199754..2200758 1 NC_019908.1 hypothetical protein 2200758 14294188 BPP43_10540 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235533.1 2199754 D 1042417 CDS YP_007235534.1 431808636 14294189 2200771..2201490 1 NC_019908.1 hypothetical protein 2201490 14294189 BPP43_10545 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235534.1 2200771 D 1042417 CDS YP_007235535.1 431808637 14294190 complement(2201507..2201725) 1 NC_019908.1 hypothetical protein 2201725 14294190 BPP43_10550 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235535.1 2201507 R 1042417 CDS YP_007235536.1 431808638 14294191 2201770..2202552 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 2202552 14294191 BPP43_10555 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235536.1 2201770 D 1042417 CDS YP_007235537.1 431808639 14294192 2202555..2203223 1 NC_019908.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 2203223 14294192 BPP43_10560 Brachyspira pilosicoli P43/6/78 ABC transporter ATP-binding protein YP_007235537.1 2202555 D 1042417 CDS YP_007235538.1 431808640 14294193 2203483..2204700 1 NC_019908.1 COG4591 ABC-type transport system, involved in lipoprotein release, permease component; hypothetical protein 2204700 14294193 BPP43_10565 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235538.1 2203483 D 1042417 CDS YP_007235539.1 431808641 14294194 2204693..2205373 1 NC_019908.1 hypothetical protein 2205373 14294194 BPP43_10570 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235539.1 2204693 D 1042417 CDS YP_007235540.1 431808642 14294195 2205397..2206461 1 NC_019908.1 hypothetical protein 2206461 14294195 BPP43_10575 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235540.1 2205397 D 1042417 CDS YP_007235541.1 431808643 14294196 complement(2206540..2206671) 1 NC_019908.1 hypothetical protein 2206671 14294196 BPP43_10580 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235541.1 2206540 R 1042417 CDS YP_007235542.1 431808644 14294197 complement(2206716..2207282) 1 NC_019908.1 hypothetical protein 2207282 14294197 BPP43_10585 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235542.1 2206716 R 1042417 CDS YP_007235543.1 431808645 14294198 complement(2207373..2208734) 1 NC_019908.1 COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); Mg/Co/Ni transporter MgtE 2208734 14294198 BPP43_10590 Brachyspira pilosicoli P43/6/78 Mg/Co/Ni transporter MgtE YP_007235543.1 2207373 R 1042417 CDS YP_007235544.1 431808646 14294199 2208864..2209844 1 NC_019908.1 COG0205 6-phosphofructokinase; 6-phosphofructokinase 2209844 14294199 BPP43_10595 Brachyspira pilosicoli P43/6/78 6-phosphofructokinase YP_007235544.1 2208864 D 1042417 CDS YP_007235545.1 431808647 14294200 2209864..2210892 1 NC_019908.1 COG1922 Teichoic acid biosynthesis proteins; UDP-N-acetyl D mannosamine transferase 2210892 14294200 BPP43_10600 Brachyspira pilosicoli P43/6/78 UDP-N-acetyl D mannosamine transferase YP_007235545.1 2209864 D 1042417 CDS YP_007235546.1 431808648 14294201 2215689..2216063 1 NC_019908.1 COG3951 Rod binding protein; peptidoglycan hydrolase FlgJ 2216063 14294201 BPP43_10625 Brachyspira pilosicoli P43/6/78 peptidoglycan hydrolase FlgJ YP_007235546.1 2215689 D 1042417 CDS YP_007235547.1 431808649 14294202 complement(2216064..2216891) 1 NC_019908.1 COG1387 Histidinol phosphatase and related hydrolases of the PHP family; histidinol-phosphatase 2216891 14294202 BPP43_10630 Brachyspira pilosicoli P43/6/78 histidinol-phosphatase YP_007235547.1 2216064 R 1042417 CDS YP_007235548.1 431808650 14294203 complement(2217448..2217540) 1 NC_019908.1 hypothetical protein 2217540 14294203 BPP43_10635 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235548.1 2217448 R 1042417 CDS YP_007235549.1 431808651 14294204 2220565..2221413 1 NC_019908.1 COG0241 Histidinol phosphatase and related phosphatases; histidinol phosphatase-like protein 2221413 14294204 BPP43_10650 Brachyspira pilosicoli P43/6/78 histidinol phosphatase-like protein YP_007235549.1 2220565 D 1042417 CDS YP_007235550.1 431808652 14294205 2221429..2221881 1 NC_019908.1 dual specificity protein phosphatase 2221881 14294205 BPP43_10655 Brachyspira pilosicoli P43/6/78 dual specificity protein phosphatase YP_007235550.1 2221429 D 1042417 CDS YP_007235551.1 431808653 14294206 2221939..2222595 1 NC_019908.1 COG1272 Predicted membrane protein, hemolysin III homolog; hemolysin III family channel protein 2222595 14294206 BPP43_10660 Brachyspira pilosicoli P43/6/78 hemolysin III family channel protein YP_007235551.1 2221939 D 1042417 CDS YP_007235552.1 431808654 14294207 2222619..2224247 1 NC_019908.1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming); long-chain-fatty-acid-CoA ligase 2224247 14294207 BPP43_10665 Brachyspira pilosicoli P43/6/78 long-chain-fatty-acid-CoA ligase YP_007235552.1 2222619 D 1042417 CDS YP_007235553.1 431808655 14294208 2224319..2225113 1 NC_019908.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; aldo/keto reductase family oxidoreductase 2225113 14294208 BPP43_10670 Brachyspira pilosicoli P43/6/78 aldo/keto reductase family oxidoreductase YP_007235553.1 2224319 D 1042417 CDS YP_007235554.1 431808656 14294209 2225153..2225779 1 NC_019908.1 COG4845 Chloramphenicol O-acetyltransferase; chloramphenicol acetyltransferase 2225779 14294209 BPP43_10675 Brachyspira pilosicoli P43/6/78 chloramphenicol acetyltransferase YP_007235554.1 2225153 D 1042417 CDS YP_007235555.1 431808657 14294210 complement(2225763..2227400) 1 NC_019908.1 COG2604 Uncharacterized protein conserved in bacteria; hypothetical protein 2227400 14294210 BPP43_10680 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235555.1 2225763 R 1042417 CDS YP_007235556.1 431808658 14294211 complement(2227397..2228149) 1 NC_019908.1 hypothetical protein 2228149 14294211 BPP43_10685 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235556.1 2227397 R 1042417 CDS YP_007235557.1 431808659 14294212 2228278..2229216 1 NC_019908.1 COG0223 Methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 2229216 14294212 BPP43_10690 Brachyspira pilosicoli P43/6/78 methionyl-tRNA formyltransferase YP_007235557.1 2228278 D 1042417 CDS YP_007235558.1 431808660 14294213 2229246..2229893 1 NC_019908.1 COG2815 Uncharacterized protein conserved in bacteria; protein PASTA domain-containing protein 2229893 14294213 BPP43_10695 Brachyspira pilosicoli P43/6/78 protein PASTA domain-containing protein YP_007235558.1 2229246 D 1042417 CDS YP_007235559.1 431808661 14294214 2230000..2230800 1 NC_019908.1 COG0500 SAM-dependent methyltransferases; 3-demethylubiquinone-9 3-O-methyltransferase 2230800 14294214 BPP43_10700 Brachyspira pilosicoli P43/6/78 3-demethylubiquinone-9 3-O-methyltransferase YP_007235559.1 2230000 D 1042417 CDS YP_007235560.1 431808662 14294215 2230821..2232536 1 NC_019908.1 COG1315 Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain; hypothetical protein 2232536 14294215 BPP43_10705 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235560.1 2230821 D 1042417 CDS YP_007235561.1 431808663 14294216 2232610..2233602 1 NC_019908.1 COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase; ADP-heptose synthase 2233602 14294216 BPP43_10710 Brachyspira pilosicoli P43/6/78 ADP-heptose synthase YP_007235561.1 2232610 D 1042417 CDS YP_007235562.1 431808664 14294217 2233612..2234742 1 NC_019908.1 hypothetical protein 2234742 14294217 BPP43_10715 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235562.1 2233612 D 1042417 CDS YP_007235563.1 431808665 14294218 complement(2234746..2234943) 1 NC_019908.1 hypothetical protein 2234943 14294218 BPP43_10720 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235563.1 2234746 R 1042417 CDS YP_007235564.1 431808666 14294219 2235267..2236439 1 NC_019908.1 COG2814 Arabinose efflux permease; arabinose efflux permease 2236439 14294219 BPP43_10725 Brachyspira pilosicoli P43/6/78 arabinose efflux permease YP_007235564.1 2235267 D 1042417 CDS YP_007235565.1 431808667 14294220 2236464..2236793 1 NC_019908.1 hypothetical protein 2236793 14294220 BPP43_10730 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235565.1 2236464 D 1042417 CDS YP_007235566.1 431808668 14294221 2236906..2237280 1 NC_019908.1 hypothetical protein 2237280 14294221 BPP43_10735 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235566.1 2236906 D 1042417 CDS YP_007235567.1 431808669 14294222 2237362..2238951 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 2238951 14294222 BPP43_10740 Brachyspira pilosicoli P43/6/78 family 5 extracellular solute-binding protein YP_007235567.1 2237362 D 1042417 CDS YP_007235568.1 431808670 14294223 complement(2238980..2239804) 1 NC_019908.1 hypothetical protein 2239804 14294223 BPP43_10745 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235568.1 2238980 R 1042417 CDS YP_007235569.1 431808671 14294224 2240002..2241945 1 NC_019908.1 COG3855 Uncharacterized protein conserved in bacteria; fructose-1,6-bisphosphatase 2241945 14294224 BPP43_10750 Brachyspira pilosicoli P43/6/78 fructose-1,6-bisphosphatase YP_007235569.1 2240002 D 1042417 CDS YP_007235570.1 431808672 14294225 2242032..2243513 1 NC_019908.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; hypothetical protein 2243513 14294225 BPP43_10755 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235570.1 2242032 D 1042417 CDS YP_007235571.1 431808673 14294226 2243514..2244254 1 NC_019908.1 COG1403 Restriction endonuclease; hypothetical protein 2244254 14294226 BPP43_10760 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235571.1 2243514 D 1042417 CDS YP_007235572.1 431808674 14294227 2244448..2245152 1 NC_019908.1 COG2171 Tetrahydrodipicolinate N-succinyltransferase; tetrahydrodipicolinate succinyltransferase domain-containing protein 2245152 14294227 BPP43_10765 Brachyspira pilosicoli P43/6/78 tetrahydrodipicolinate succinyltransferase domain-containing protein YP_007235572.1 2244448 D 1042417 CDS YP_007235573.1 431808675 14294228 2245306..2246478 1 NC_019908.1 COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family; iron-containing alcohol dehydrogenase 2246478 14294228 BPP43_10770 Brachyspira pilosicoli P43/6/78 iron-containing alcohol dehydrogenase YP_007235573.1 2245306 D 1042417 CDS YP_007235574.1 431808676 14294229 complement(2246761..2247768) 1 NC_019908.1 COG1559 Predicted periplasmic solute-binding protein; aminodeoxychorismate lyase 2247768 14294229 BPP43_10775 Brachyspira pilosicoli P43/6/78 aminodeoxychorismate lyase YP_007235574.1 2246761 R 1042417 CDS YP_007235575.1 431808677 14294230 2247956..2250343 1 NC_019908.1 COG3808 Inorganic pyrophosphatase; membrane-bound proton-translocating pyrophosphatase 2250343 hppA 14294230 hppA Brachyspira pilosicoli P43/6/78 membrane-bound proton-translocating pyrophosphatase YP_007235575.1 2247956 D 1042417 CDS YP_007235576.1 431808678 14294231 2250566..2251330 1 NC_019908.1 COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; hypothetical protein 2251330 14294231 BPP43_10785 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235576.1 2250566 D 1042417 CDS YP_007235577.1 431808679 14294232 2251400..2252332 1 NC_019908.1 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain; DeoR family transcriptional regulator 2252332 14294232 BPP43_10790 Brachyspira pilosicoli P43/6/78 DeoR family transcriptional regulator YP_007235577.1 2251400 D 1042417 CDS YP_007235578.1 431808680 14294233 2252703..2254982 1 NC_019908.1 COG3119 Arylsulfatase A and related enzymes; sulfatase 2254982 14294233 BPP43_10795 Brachyspira pilosicoli P43/6/78 sulfatase YP_007235578.1 2252703 D 1042417 CDS YP_007235579.1 431808681 14294234 2255352..2257721 1 NC_019908.1 COG3119 Arylsulfatase A and related enzymes; sulfatase 2257721 14294234 BPP43_10800 Brachyspira pilosicoli P43/6/78 sulfatase YP_007235579.1 2255352 D 1042417 CDS YP_007235580.1 431808682 14294235 2257750..2260116 1 NC_019908.1 COG3119 Arylsulfatase A and related enzymes; sulfatase 2260116 14294235 BPP43_10805 Brachyspira pilosicoli P43/6/78 sulfatase YP_007235580.1 2257750 D 1042417 CDS YP_007235581.1 431808683 14294236 2260274..2261509 1 NC_019908.1 COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); arylsulfatase activating protein AslB 2261509 14294236 BPP43_10810 Brachyspira pilosicoli P43/6/78 arylsulfatase activating protein AslB YP_007235581.1 2260274 D 1042417 CDS YP_007235582.1 431808684 14294237 2261572..2262363 1 NC_019908.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein 2262363 14294237 BPP43_10815 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235582.1 2261572 D 1042417 CDS YP_007235583.1 431808685 14294238 2262469..2263902 1 NC_019908.1 COG0591 Na+/proline symporter; sodium:solute symport protein 2263902 14294238 BPP43_10820 Brachyspira pilosicoli P43/6/78 sodium:solute symport protein YP_007235583.1 2262469 D 1042417 CDS YP_007235584.1 431808686 14294239 complement(2263973..2264884) 1 NC_019908.1 COG0739 Membrane proteins related to metalloendopeptidases; peptidase 2264884 14294239 BPP43_10825 Brachyspira pilosicoli P43/6/78 peptidase YP_007235584.1 2263973 R 1042417 CDS YP_007235585.1 431808687 14294240 complement(2265103..2266137) 1 NC_019908.1 COG2255 Holliday junction resolvasome, helicase subunit; Holliday junction DNA helicase RuvB 2266137 14294240 BPP43_10830 Brachyspira pilosicoli P43/6/78 Holliday junction DNA helicase RuvB YP_007235585.1 2265103 R 1042417 CDS YP_007235586.1 431808688 14294241 complement(2266295..2268652) 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 2268652 14294241 BPP43_10835 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007235586.1 2266295 R 1042417 CDS YP_007235587.1 431808689 14294242 complement(2268735..2270699) 1 NC_019908.1 COG0557 Exoribonuclease R; ribonuclease R 2270699 14294242 BPP43_10840 Brachyspira pilosicoli P43/6/78 ribonuclease R YP_007235587.1 2268735 R 1042417 CDS YP_007235588.1 431808690 14294243 complement(2270990..2271844) 1 NC_019908.1 hypothetical protein 2271844 14294243 BPP43_10845 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235588.1 2270990 R 1042417 CDS YP_007235589.1 431808691 14294244 2272542..2274005 1 NC_019908.1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; cardiolipin synthase 2274005 14294244 BPP43_10850 Brachyspira pilosicoli P43/6/78 cardiolipin synthase YP_007235589.1 2272542 D 1042417 CDS YP_007235590.1 431808692 14294245 2274027..2274956 1 NC_019908.1 COG4886 Leucine-rich repeat (LRR) protein; hypothetical protein 2274956 14294245 BPP43_10855 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235590.1 2274027 D 1042417 CDS YP_007235591.1 431808693 14294246 complement(2274953..2275924) 1 NC_019908.1 COG0794 Predicted sugar phosphate isomerase involved in capsule formation; polysialic acid capsule expression protein 2275924 14294246 BPP43_10860 Brachyspira pilosicoli P43/6/78 polysialic acid capsule expression protein YP_007235591.1 2274953 R 1042417 CDS YP_007235592.1 431808694 14294247 complement(2275943..2276071) 1 NC_019908.1 hypothetical protein 2276071 14294247 BPP43_10865 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235592.1 2275943 R 1042417 CDS YP_007235593.1 431808695 14294248 complement(2276081..2276446) 1 NC_019908.1 COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; endonuclease 2276446 14294248 BPP43_10870 Brachyspira pilosicoli P43/6/78 endonuclease YP_007235593.1 2276081 R 1042417 CDS YP_007235594.1 431808696 14294249 complement(2276447..2277676) 1 NC_019908.1 COG2206 HD-GYP domain; HD GYP domain-containing protein 2277676 14294249 BPP43_10875 Brachyspira pilosicoli P43/6/78 HD GYP domain-containing protein YP_007235594.1 2276447 R 1042417 CDS YP_007235595.1 431808697 14294250 complement(2277932..2278993) 1 NC_019908.1 hypothetical protein 2278993 14294250 BPP43_10890 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235595.1 2277932 R 1042417 CDS YP_007235596.1 431808698 14294251 complement(2279663..2281804) 1 NC_019908.1 hypothetical protein 2281804 14294251 BPP43_10905 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235596.1 2279663 R 1042417 CDS YP_007235597.1 431808699 14294252 2281785..2281940 1 NC_019908.1 hypothetical protein 2281940 14294252 BPP43_10910 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235597.1 2281785 D 1042417 CDS YP_007235598.1 431808700 14294253 2281933..2283315 1 NC_019908.1 COG2812 DNA polymerase III, gamma/tau subunits; DNA polymerase III subunit gamma 2283315 14294253 BPP43_10915 Brachyspira pilosicoli P43/6/78 DNA polymerase III subunit gamma YP_007235598.1 2281933 D 1042417 CDS YP_007235599.1 431808701 14294254 2283335..2284351 1 NC_019908.1 hypothetical protein 2284351 14294254 BPP43_10920 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235599.1 2283335 D 1042417 CDS YP_007235600.1 431808702 14294255 2284510..2285106 1 NC_019908.1 COG0605 Superoxide dismutase; superoxide dismutase 2285106 14294255 BPP43_10925 Brachyspira pilosicoli P43/6/78 superoxide dismutase YP_007235600.1 2284510 D 1042417 CDS YP_007235601.1 431808703 14294256 2285143..2285679 1 NC_019908.1 COG1592 Rubrerythrin; rubrerythrin 2285679 14294256 BPP43_10930 Brachyspira pilosicoli P43/6/78 rubrerythrin YP_007235601.1 2285143 D 1042417 CDS YP_007235602.1 431808704 14294257 2285819..2286679 1 NC_019908.1 COG2962 Predicted permeases; permease 2286679 14294257 BPP43_10935 Brachyspira pilosicoli P43/6/78 permease YP_007235602.1 2285819 D 1042417 CDS YP_007235603.1 431808705 14294258 complement(2286759..2287934) 1 NC_019908.1 COG3007 Uncharacterized paraquat-inducible protein B; trans-2-enoyl-CoA reductase 2287934 14294258 BPP43_10940 Brachyspira pilosicoli P43/6/78 trans-2-enoyl-CoA reductase YP_007235603.1 2286759 R 1042417 CDS YP_007235604.1 431808706 14294259 2288050..2289042 1 NC_019908.1 COG0500 SAM-dependent methyltransferases; FkbM family methyltransferase 2289042 14294259 BPP43_10945 Brachyspira pilosicoli P43/6/78 FkbM family methyltransferase YP_007235604.1 2288050 D 1042417 CDS YP_007235605.1 431808707 14294260 complement(2289079..2289288) 1 NC_019908.1 hypothetical protein 2289288 14294260 BPP43_10950 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235605.1 2289079 R 1042417 CDS YP_007235606.1 431808708 14294261 complement(2289319..2290005) 1 NC_019908.1 COG0569 K+ transport systems, NAD-binding component; potassium uptake protein TrkA 2290005 14294261 BPP43_10955 Brachyspira pilosicoli P43/6/78 potassium uptake protein TrkA YP_007235606.1 2289319 R 1042417 CDS YP_007235607.1 431808709 14294262 2290227..2290733 1 NC_019908.1 hypothetical protein 2290733 14294262 BPP43_10960 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235607.1 2290227 D 1042417 CDS YP_007235608.1 431808710 14294263 2290754..2291533 1 NC_019908.1 COG4221 Short-chain alcohol dehydrogenase of unknown specificity; short-chain dehydrogenase 2291533 14294263 BPP43_10965 Brachyspira pilosicoli P43/6/78 short-chain dehydrogenase YP_007235608.1 2290754 D 1042417 CDS YP_007235609.1 431808711 14294264 2291564..2293141 1 NC_019908.1 hypothetical protein 2293141 14294264 BPP43_10970 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235609.1 2291564 D 1042417 CDS YP_007235610.1 431808712 14294265 2293464..2294393 1 NC_019908.1 COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis lauroyl acyltransferase 2294393 14294265 BPP43_10975 Brachyspira pilosicoli P43/6/78 lipid A biosynthesis lauroyl acyltransferase YP_007235610.1 2293464 D 1042417 CDS YP_007235611.1 431808713 14294266 2294503..2296011 1 NC_019908.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; serine endoprotease 2296011 14294266 BPP43_10980 Brachyspira pilosicoli P43/6/78 serine endoprotease YP_007235611.1 2294503 D 1042417 CDS YP_007235612.1 431808714 14294267 2296533..2297276 1 NC_019908.1 COG0101 Pseudouridylate synthase; tRNA-pseudouridine synthase TrmA 2297276 14294267 BPP43_10985 Brachyspira pilosicoli P43/6/78 tRNA-pseudouridine synthase TrmA YP_007235612.1 2296533 D 1042417 CDS YP_007235613.1 431808715 14294268 2297318..2298361 1 NC_019908.1 COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; 3-deoxy-7-phosphoheptulonate synthase 2298361 14294268 BPP43_10990 Brachyspira pilosicoli P43/6/78 3-deoxy-7-phosphoheptulonate synthase YP_007235613.1 2297318 D 1042417 CDS YP_007235614.1 431808716 14294269 2298570..2299025 1 NC_019908.1 COG0102 Ribosomal protein L13; 50S ribosomal protein L13 2299025 14294269 BPP43_10995 Brachyspira pilosicoli P43/6/78 50S ribosomal protein L13 YP_007235614.1 2298570 D 1042417 CDS YP_007235615.1 431808717 14294270 2299040..2299438 1 NC_019908.1 COG0103 Ribosomal protein S9; 30S ribosomal protein S9 2299438 14294270 BPP43_11000 Brachyspira pilosicoli P43/6/78 30S ribosomal protein S9 YP_007235615.1 2299040 D 1042417 CDS YP_007235616.1 431808718 14294271 2299482..2299847 1 NC_019908.1 COG1734 DnaK suppressor protein; DnaK suppressor 2299847 14294271 BPP43_11005 Brachyspira pilosicoli P43/6/78 DnaK suppressor YP_007235616.1 2299482 D 1042417 CDS YP_007235617.1 431808719 14294272 2299847..2301841 1 NC_019908.1 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; primosomal protein N 2301841 14294272 BPP43_11010 Brachyspira pilosicoli P43/6/78 primosomal protein N YP_007235617.1 2299847 D 1042417 CDS YP_007235618.1 431808720 14294273 complement(2301838..2302446) 1 NC_019908.1 COG0784 FOG: CheY-like receiver; diguanylate cyclase 2302446 14294273 BPP43_11015 Brachyspira pilosicoli P43/6/78 diguanylate cyclase YP_007235618.1 2301838 R 1042417 CDS YP_007235619.1 431808721 14294274 complement(2302548..2303333) 1 NC_019908.1 nucleotidyltransferase domain-containing protein 2303333 14294274 BPP43_11020 Brachyspira pilosicoli P43/6/78 nucleotidyltransferase domain-containing protein YP_007235619.1 2302548 R 1042417 CDS YP_007235620.1 431808722 14294275 2303481..2304233 1 NC_019908.1 pyridoxine kinase 2304233 14294275 BPP43_11025 Brachyspira pilosicoli P43/6/78 pyridoxine kinase YP_007235620.1 2303481 D 1042417 CDS YP_007235621.1 431808723 14294276 2304221..2305258 1 NC_019908.1 hypothetical protein 2305258 14294276 BPP43_11030 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235621.1 2304221 D 1042417 CDS YP_007235622.1 431808724 14294277 2305726..2305860 1 NC_019908.1 hypothetical protein 2305860 14294277 BPP43_11035 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235622.1 2305726 D 1042417 CDS YP_007235623.1 431808725 14294278 2305829..2306293 1 NC_019908.1 hypothetical protein 2306293 14294278 BPP43_11040 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235623.1 2305829 D 1042417 CDS YP_007235624.1 431808726 14294279 complement(2306427..2308418) 1 NC_019908.1 COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); NAD-dependent DNA ligase 2308418 14294279 BPP43_11045 Brachyspira pilosicoli P43/6/78 NAD-dependent DNA ligase YP_007235624.1 2306427 R 1042417 CDS YP_007235625.1 431808727 14294280 2309281..2310726 1 NC_019908.1 COG3839 ABC-type sugar transport systems, ATPase components; hypothetical protein 2310726 14294280 BPP43_11050 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235625.1 2309281 D 1042417 CDS YP_007235626.1 431808728 14294281 2310849..2311319 1 NC_019908.1 hypothetical protein 2311319 14294281 BPP43_11055 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235626.1 2310849 D 1042417 CDS YP_007235627.1 431808729 14294282 2311583..2312095 1 NC_019908.1 COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; adenine phosphoribosyltransferase 2312095 14294282 BPP43_11060 Brachyspira pilosicoli P43/6/78 adenine phosphoribosyltransferase YP_007235627.1 2311583 D 1042417 CDS YP_007235628.1 431808730 14294283 complement(2312194..2313795) 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 2313795 14294283 BPP43_11065 Brachyspira pilosicoli P43/6/78 family 5 extracellular solute-binding protein YP_007235628.1 2312194 R 1042417 CDS YP_007235629.1 431808731 14294284 complement(2313885..2314760) 1 NC_019908.1 COG1145 Ferredoxin; iron-sulfur cluster-binding protein 2314760 14294284 BPP43_11070 Brachyspira pilosicoli P43/6/78 iron-sulfur cluster-binding protein YP_007235629.1 2313885 R 1042417 CDS YP_007235630.1 431808732 14294285 2314919..2316121 1 NC_019908.1 hypothetical protein 2316121 14294285 BPP43_11075 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235630.1 2314919 D 1042417 CDS YP_007235631.1 431808733 14294286 complement(2316191..2317936) 1 NC_019908.1 COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); phosphoenolpyruvate protein phosphotransferase 2317936 14294286 BPP43_11080 Brachyspira pilosicoli P43/6/78 phosphoenolpyruvate protein phosphotransferase YP_007235631.1 2316191 R 1042417 CDS YP_007235632.1 431808734 14294287 complement(2317956..2318222) 1 NC_019908.1 COG1925 Phosphotransferase system, HPr-related proteins; phosphocarrier protein HPr 2318222 14294287 BPP43_11085 Brachyspira pilosicoli P43/6/78 phosphocarrier protein HPr YP_007235632.1 2317956 R 1042417 CDS YP_007235633.1 431808735 14294288 complement(2318351..2319133) 1 NC_019908.1 COG1521 Putative transcriptional regulator, homolog of Bvg accessory factor; pantothenate kinase 2319133 14294288 BPP43_11090 Brachyspira pilosicoli P43/6/78 pantothenate kinase YP_007235633.1 2318351 R 1042417 CDS YP_007235634.1 431808736 14294289 complement(2319136..2320530) 1 NC_019908.1 COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; polyA polymerase family protein 2320530 14294289 BPP43_11095 Brachyspira pilosicoli P43/6/78 polyA polymerase family protein YP_007235634.1 2319136 R 1042417 CDS YP_007235635.1 431808737 14294290 complement(2320667..2321029) 1 NC_019908.1 COG3862 Uncharacterized protein with conserved CXXC pairs; hypothetical protein 2321029 14294290 BPP43_11100 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235635.1 2320667 R 1042417 CDS YP_007235636.1 431808738 14294291 complement(2321084..2321950) 1 NC_019908.1 COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; arginase 2321950 14294291 BPP43_11105 Brachyspira pilosicoli P43/6/78 arginase YP_007235636.1 2321084 R 1042417 CDS YP_007235637.1 431808739 14294292 complement(2322020..2323294) 1 NC_019908.1 COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; sarcosine oxidase subunit alpha 2323294 14294292 BPP43_11110 Brachyspira pilosicoli P43/6/78 sarcosine oxidase subunit alpha YP_007235637.1 2322020 R 1042417 CDS YP_007235638.1 431808740 14294293 complement(2323503..2324942) 1 NC_019908.1 COG0579 Predicted dehydrogenase; dehydrogenase 2324942 14294293 BPP43_11115 Brachyspira pilosicoli P43/6/78 dehydrogenase YP_007235638.1 2323503 R 1042417 CDS YP_007235639.1 431808741 14294294 complement(2325058..2326542) 1 NC_019908.1 COG0554 Glycerol kinase; glycerol kinase 2326542 14294294 BPP43_11120 Brachyspira pilosicoli P43/6/78 glycerol kinase YP_007235639.1 2325058 R 1042417 CDS YP_007235640.1 431808742 14294295 complement(2326579..2327319) 1 NC_019908.1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator protein 2327319 14294295 BPP43_11125 Brachyspira pilosicoli P43/6/78 glycerol uptake facilitator protein YP_007235640.1 2326579 R 1042417 CDS YP_007235641.1 431808743 14294296 complement(2327361..2327858) 1 NC_019908.1 COG1592 Rubrerythrin; rubrerythrin 2327858 14294296 BPP43_11130 Brachyspira pilosicoli P43/6/78 rubrerythrin YP_007235641.1 2327361 R 1042417 CDS YP_007235642.1 431808744 14294297 complement(2328156..2328302) 1 NC_019908.1 hypothetical protein 2328302 14294297 BPP43_11135 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235642.1 2328156 R 1042417 CDS YP_007235643.1 431808745 14294298 2328457..2329737 1 NC_019908.1 COG0172 Seryl-tRNA synthetase; seryl-tRNA synthetase 2329737 14294298 BPP43_11140 Brachyspira pilosicoli P43/6/78 seryl-tRNA synthetase YP_007235643.1 2328457 D 1042417 CDS YP_007235644.1 431808746 14294299 2329737..2330057 1 NC_019908.1 COG3070 Regulator of competence-specific genes; TfoX family protein 2330057 14294299 BPP43_11145 Brachyspira pilosicoli P43/6/78 TfoX family protein YP_007235644.1 2329737 D 1042417 CDS YP_007235645.1 431808747 14294300 complement(2330484..2332079) 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 2332079 14294300 BPP43_11150 Brachyspira pilosicoli P43/6/78 family 5 extracellular solute-binding protein YP_007235645.1 2330484 R 1042417 CDS YP_007235646.1 431808748 14294301 complement(2332185..2333531) 1 NC_019908.1 COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; adenosylmethionine-8-amino-7-oxononanoate transaminase 2333531 14294301 BPP43_11155 Brachyspira pilosicoli P43/6/78 adenosylmethionine-8-amino-7-oxononanoate transaminase YP_007235646.1 2332185 R 1042417 CDS YP_007235647.1 431808749 14294302 complement(2333574..2334239) 1 NC_019908.1 COG0132 Dethiobiotin synthetase; dethiobiotin synthase 2334239 14294302 BPP43_11160 Brachyspira pilosicoli P43/6/78 dethiobiotin synthase YP_007235647.1 2333574 R 1042417 CDS YP_007235648.1 431808750 14294303 complement(2334269..2335264) 1 NC_019908.1 COG0502 Biotin synthase and related enzymes; biotin synthase 2335264 14294303 BPP43_11165 Brachyspira pilosicoli P43/6/78 biotin synthase YP_007235648.1 2334269 R 1042417 CDS YP_007235649.1 431808751 14294304 complement(2335450..2336280) 1 NC_019908.1 COG1654 Biotin operon repressor; biotin--protein ligase 2336280 14294304 BPP43_11170 Brachyspira pilosicoli P43/6/78 biotin--protein ligase YP_007235649.1 2335450 R 1042417 CDS YP_007235650.1 431808752 14294305 2338448..2341087 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 2341087 14294305 BPP43_11185 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235650.1 2338448 D 1042417 CDS YP_007235651.1 431808753 14294306 complement(2343126..2344493) 1 NC_019908.1 COG4452 Inner membrane protein involved in colicin E2 resistance; inner membrane protein 2344493 14294306 BPP43_11200 Brachyspira pilosicoli P43/6/78 inner membrane protein YP_007235651.1 2343126 R 1042417 CDS YP_007235652.1 431808754 14294307 2344787..2345947 1 NC_019908.1 COG1454 Alcohol dehydrogenase, class IV; iron-containing alcohol dehydrogenase 2345947 14294307 BPP43_11205 Brachyspira pilosicoli P43/6/78 iron-containing alcohol dehydrogenase YP_007235652.1 2344787 D 1042417 CDS YP_007235653.1 431808755 14294308 2346084..2348132 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein B 2348132 14294308 BPP43_11210 Brachyspira pilosicoli P43/6/78 methyl-accepting chemotaxis protein B YP_007235653.1 2346084 D 1042417 CDS YP_007235654.1 431808756 14294309 complement(2348165..2348842) 1 NC_019908.1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; RNA pseudouridine synthase family protein 2348842 14294309 BPP43_11215 Brachyspira pilosicoli P43/6/78 RNA pseudouridine synthase family protein YP_007235654.1 2348165 R 1042417 CDS YP_007235655.1 431808757 14294310 2349060..2349890 1 NC_019908.1 flagellar filament outer layer protein FlaA 2349890 14294310 BPP43_11220 Brachyspira pilosicoli P43/6/78 flagellar filament outer layer protein FlaA YP_007235655.1 2349060 D 1042417 CDS YP_007235656.1 431808758 14294311 2349915..2350598 1 NC_019908.1 flagellar filament outer layer protein FlaA-2 2350598 14294311 BPP43_11225 Brachyspira pilosicoli P43/6/78 flagellar filament outer layer protein FlaA-2 YP_007235656.1 2349915 D 1042417 CDS YP_007235657.1 431808759 14294312 2350684..2350791 1 NC_019908.1 hypothetical protein 2350791 14294312 BPP43_11230 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235657.1 2350684 D 1042417 CDS YP_007235658.1 431808760 14294313 complement(2350788..2354378) 1 NC_019908.1 COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor 2354378 14294313 BPP43_11235 Brachyspira pilosicoli P43/6/78 transcription-repair coupling factor YP_007235658.1 2350788 R 1042417 CDS YP_007235659.1 431808761 14294314 2354522..2356246 1 NC_019908.1 COG0500 SAM-dependent methyltransferases; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase 2356246 14294314 BPP43_11240 Brachyspira pilosicoli P43/6/78 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase YP_007235659.1 2354522 D 1042417 CDS YP_007235660.1 431808762 14294315 2356313..2356852 1 NC_019908.1 hypothetical protein 2356852 14294315 BPP43_11245 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235660.1 2356313 D 1042417 CDS YP_007235661.1 431808763 14294316 2356875..2357951 1 NC_019908.1 COG3853 Uncharacterized protein involved in tellurite resistance; toxic anion resistance family protein 2357951 14294316 BPP43_11250 Brachyspira pilosicoli P43/6/78 toxic anion resistance family protein YP_007235661.1 2356875 D 1042417 CDS YP_007235662.1 431808764 14294317 2357954..2358550 1 NC_019908.1 COG2091 Phosphopantetheinyl transferase; phosphopantetheinyl transferase 2358550 14294317 BPP43_11255 Brachyspira pilosicoli P43/6/78 phosphopantetheinyl transferase YP_007235662.1 2357954 D 1042417 CDS YP_007235663.1 431808765 14294318 2358644..2359633 1 NC_019908.1 hypothetical protein 2359633 14294318 BPP43_11260 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235663.1 2358644 D 1042417 CDS YP_007235664.1 431808766 14294319 2359711..2360841 1 NC_019908.1 COG2006 Uncharacterized conserved protein; iron-sulfur cluster-binding protein 2360841 14294319 BPP43_11265 Brachyspira pilosicoli P43/6/78 iron-sulfur cluster-binding protein YP_007235664.1 2359711 D 1042417 CDS YP_007235665.1 431808767 14294320 2360925..2361389 1 NC_019908.1 COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases; (3R)-hydroxymyristoyl-ACP dehydratase 2361389 14294320 BPP43_11270 Brachyspira pilosicoli P43/6/78 (3R)-hydroxymyristoyl-ACP dehydratase YP_007235665.1 2360925 D 1042417 CDS YP_007235666.1 431808768 14294321 2361415..2362209 1 NC_019908.1 COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase; UDP-N-acetylglucosamine acyltransferase 2362209 14294321 BPP43_11275 Brachyspira pilosicoli P43/6/78 UDP-N-acetylglucosamine acyltransferase YP_007235666.1 2361415 D 1042417 CDS YP_007235667.1 431808769 14294322 2362231..2363352 1 NC_019908.1 COG0763 Lipid A disaccharide synthetase; lipid-A-disaccharide synthase 2363352 14294322 BPP43_11280 Brachyspira pilosicoli P43/6/78 lipid-A-disaccharide synthase YP_007235667.1 2362231 D 1042417 CDS YP_007235668.1 431808770 14294323 2363355..2364146 1 NC_019908.1 hypothetical protein 2364146 14294323 BPP43_11285 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235668.1 2363355 D 1042417 CDS YP_007235669.1 431808771 14294324 complement(2364143..2365873) 1 NC_019908.1 COG0532 Translation initiation factor 2 (IF-2; GTPase); translation initiation factor IF-2 2365873 14294324 BPP43_11290 Brachyspira pilosicoli P43/6/78 translation initiation factor IF-2 YP_007235669.1 2364143 R 1042417 CDS YP_007235670.1 431808772 14294325 complement(2366083..2366472) 1 NC_019908.1 hypothetical protein 2366472 14294325 BPP43_11295 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235670.1 2366083 R 1042417 CDS YP_007235671.1 431808773 14294326 complement(2366548..2367273) 1 NC_019908.1 hypothetical protein 2367273 14294326 BPP43_11300 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235671.1 2366548 R 1042417 CDS YP_007235672.1 431808774 14294327 complement(2367362..2368855) 1 NC_019908.1 hypothetical protein 2368855 14294327 BPP43_11305 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235672.1 2367362 R 1042417 CDS YP_007235673.1 431808775 14294328 complement(2369831..2370631) 1 NC_019908.1 COG1360 Flagellar motor protein; flagellar motor protein MotB 2370631 14294328 BPP43_11320 Brachyspira pilosicoli P43/6/78 flagellar motor protein MotB YP_007235673.1 2369831 R 1042417 CDS YP_007235674.1 431808776 14294329 complement(2370650..2371441) 1 NC_019908.1 COG1291 Flagellar motor component; flagellar Motor Protein MotA 2371441 14294329 BPP43_11325 Brachyspira pilosicoli P43/6/78 flagellar Motor Protein MotA YP_007235674.1 2370650 R 1042417 CDS YP_007235675.1 431808777 14294330 complement(2371484..2371708) 1 NC_019908.1 COG1582 Uncharacterized protein, possibly involved in motility; flagellar family protein 2371708 14294330 BPP43_11330 Brachyspira pilosicoli P43/6/78 flagellar family protein YP_007235675.1 2371484 R 1042417 CDS YP_007235676.1 431808778 14294331 complement(2371772..2373097) 1 NC_019908.1 COG1749 Flagellar hook protein FlgE; flagellar hook protein FlgE 2373097 flgE 14294331 flgE Brachyspira pilosicoli P43/6/78 flagellar hook protein FlgE YP_007235676.1 2371772 R 1042417 CDS YP_007235677.1 431808779 14294332 complement(2373388..2373819) 1 NC_019908.1 hypothetical protein 2373819 14294332 BPP43_11340 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235677.1 2373388 R 1042417 CDS YP_007235678.1 431808780 14294333 complement(2374089..2374256) 1 NC_019908.1 hypothetical protein 2374256 14294333 BPP43_11345 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235678.1 2374089 R 1042417 CDS YP_007235679.1 431808781 14294334 2374300..2375973 1 NC_019908.1 hypothetical protein 2375973 14294334 BPP43_11350 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235679.1 2374300 D 1042417 CDS YP_007235680.1 431808782 14294335 complement(2375990..2376451) 1 NC_019908.1 COG2606 Uncharacterized conserved protein; YbaK/prolyl-tRNA synthetase associated domain-containing protein 2376451 14294335 BPP43_11355 Brachyspira pilosicoli P43/6/78 YbaK/prolyl-tRNA synthetase associated domain-containing protein YP_007235680.1 2375990 R 1042417 CDS YP_007235681.1 431808783 14294336 complement(2376465..2377280) 1 NC_019908.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; RarD permease 2377280 14294336 BPP43_11360 Brachyspira pilosicoli P43/6/78 RarD permease YP_007235681.1 2376465 R 1042417 CDS YP_007235682.1 431808784 14294337 2377487..2378371 1 NC_019908.1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; phytochrome sensor protein 2378371 14294337 BPP43_11365 Brachyspira pilosicoli P43/6/78 phytochrome sensor protein YP_007235682.1 2377487 D 1042417 CDS YP_007235683.1 431808785 14294338 complement(2378566..2379363) 1 NC_019908.1 COG0024 Methionine aminopeptidase; methionine aminopeptidase 2379363 14294338 BPP43_11370 Brachyspira pilosicoli P43/6/78 methionine aminopeptidase YP_007235683.1 2378566 R 1042417 CDS YP_007235684.1 431808786 14294339 complement(2379378..2379644) 1 NC_019908.1 hypothetical protein 2379644 14294339 BPP43_11375 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235684.1 2379378 R 1042417 CDS YP_007235685.1 431808787 14294340 complement(2382497..2384494) 1 NC_019908.1 hypothetical protein 2384494 14294340 BPP43_11390 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235685.1 2382497 R 1042417 CDS YP_007235686.1 431808788 14294341 complement(2384614..2385435) 1 NC_019908.1 COG1387 Histidinol phosphatase and related hydrolases of the PHP family; histidinol-phosphatase-like protein 2385435 14294341 BPP43_11395 Brachyspira pilosicoli P43/6/78 histidinol-phosphatase-like protein YP_007235686.1 2384614 R 1042417 CDS YP_007235687.1 431808789 14294342 complement(2385596..2386681) 1 NC_019908.1 COG1064 Zn-dependent alcohol dehydrogenases; alcohol dehydrogenase 2386681 14294342 BPP43_11400 Brachyspira pilosicoli P43/6/78 alcohol dehydrogenase YP_007235687.1 2385596 R 1042417 CDS YP_007235688.1 431808790 14294343 2387041..2387943 1 NC_019908.1 COG0812 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylmuramate dehydrogenase 2387943 14294343 BPP43_11405 Brachyspira pilosicoli P43/6/78 UDP-N-acetylmuramate dehydrogenase YP_007235688.1 2387041 D 1042417 CDS YP_007235689.1 431808791 14294345 2389159..2389743 1 NC_019908.1 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; peptidoglycan-associated lipoprotein 2389743 14294345 BPP43_11420 Brachyspira pilosicoli P43/6/78 peptidoglycan-associated lipoprotein YP_007235689.1 2389159 D 1042417 CDS YP_007235690.1 431808792 14294346 2389767..2390363 1 NC_019908.1 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; peptidoglycan-associated lipoprotein 2390363 14294346 BPP43_11425 Brachyspira pilosicoli P43/6/78 peptidoglycan-associated lipoprotein YP_007235690.1 2389767 D 1042417 CDS YP_007235691.1 431808793 14294347 2390459..2391577 1 NC_019908.1 COG1413 FOG: HEAT repeat; hypothetical protein 2391577 14294347 BPP43_11430 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235691.1 2390459 D 1042417 CDS YP_007235692.1 431808794 14294348 2391577..2391855 1 NC_019908.1 hypothetical protein 2391855 14294348 BPP43_11435 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235692.1 2391577 D 1042417 CDS YP_007235693.1 431808795 14294349 complement(2392226..2392927) 1 NC_019908.1 COG1843 Flagellar hook capping protein; flagellar hook capping protein FlgD 2392927 14294349 BPP43_11440 Brachyspira pilosicoli P43/6/78 flagellar hook capping protein FlgD YP_007235693.1 2392226 R 1042417 CDS YP_007235694.1 431808796 14294350 complement(2392968..2394482) 1 NC_019908.1 COG3144 Flagellar hook-length control protein; flagellar hook-length control protein FliK 2394482 14294350 BPP43_11445 Brachyspira pilosicoli P43/6/78 flagellar hook-length control protein FliK YP_007235694.1 2392968 R 1042417 CDS YP_007235695.1 431808797 14294351 complement(2394600..2395208) 1 NC_019908.1 COG1704 Uncharacterized conserved protein; LemA family protein 2395208 14294351 BPP43_11450 Brachyspira pilosicoli P43/6/78 LemA family protein YP_007235695.1 2394600 R 1042417 CDS YP_007235696.1 431808798 14294352 complement(2395288..2395941) 1 NC_019908.1 COG2314 Predicted membrane protein; TM2 domain-containing protein 2395941 14294352 BPP43_11455 Brachyspira pilosicoli P43/6/78 TM2 domain-containing protein YP_007235696.1 2395288 R 1042417 CDS YP_007235697.1 431808799 14294353 complement(2396972..2397946) 1 NC_019908.1 COG1085 Galactose-1-phosphate uridylyltransferase; galactose-1-phosphate uridylyltransferase 2397946 14294353 BPP43_11470 Brachyspira pilosicoli P43/6/78 galactose-1-phosphate uridylyltransferase YP_007235697.1 2396972 R 1042417 CDS YP_007235698.1 431808800 14294354 2398207..2398818 1 NC_019908.1 COG1592 Rubrerythrin; rubrerythrin 2398818 14294354 BPP43_11475 Brachyspira pilosicoli P43/6/78 rubrerythrin YP_007235698.1 2398207 D 1042417 CDS YP_007235699.1 431808801 14294355 2399160..2400308 1 NC_019908.1 COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; R-2-hydroxyglutaryl-CoA dehydratase subunit 2400308 14294355 BPP43_11480 Brachyspira pilosicoli P43/6/78 R-2-hydroxyglutaryl-CoA dehydratase subunit YP_007235699.1 2399160 D 1042417 CDS YP_007235700.1 431808802 14294356 2400355..2401494 1 NC_019908.1 COG0520 Selenocysteine lyase; hypothetical protein 2401494 14294356 BPP43_11485 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235700.1 2400355 D 1042417 CDS YP_007235701.1 431808803 14294357 2401577..2402647 1 NC_019908.1 COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); CoA-substrate-specific enzyme activase 2402647 14294357 BPP43_11490 Brachyspira pilosicoli P43/6/78 CoA-substrate-specific enzyme activase YP_007235701.1 2401577 D 1042417 CDS YP_007235702.1 431808804 14294358 complement(2403097..2404533) 1 NC_019908.1 COG0044 Dihydroorotase and related cyclic amidohydrolases; phenylhydantoinase 2404533 14294358 BPP43_11495 Brachyspira pilosicoli P43/6/78 phenylhydantoinase YP_007235702.1 2403097 R 1042417 CDS YP_007235703.1 431808805 14294359 2404689..2406857 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 2406857 14294359 BPP43_11500 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007235703.1 2404689 D 1042417 CDS YP_007235704.1 431808806 14294360 complement(2407377..2407940) 1 NC_019908.1 outer membrane lipoprotein 2407940 14294360 BPP43_11505 Brachyspira pilosicoli P43/6/78 outer membrane lipoprotein YP_007235704.1 2407377 R 1042417 CDS YP_007235705.1 431808807 14294361 complement(2408798..2409625) 1 NC_019908.1 COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; synthase 2409625 14294361 BPP43_11510 Brachyspira pilosicoli P43/6/78 synthase YP_007235705.1 2408798 R 1042417 CDS YP_007235706.1 431808808 14294362 complement(2409629..2412202) 1 NC_019908.1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; CoxL protein 2412202 14294362 BPP43_11515 Brachyspira pilosicoli P43/6/78 CoxL protein YP_007235706.1 2409629 R 1042417 CDS YP_007235707.1 431808809 14294363 complement(2412303..2415278) 1 NC_019908.1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; selenate reductase subunit YgfK 2415278 14294363 BPP43_11520 Brachyspira pilosicoli P43/6/78 selenate reductase subunit YgfK YP_007235707.1 2412303 R 1042417 CDS YP_007235708.1 431808810 14294364 complement(2415375..2416706) 1 NC_019908.1 COG0402 Cytosine deaminase and related metal-dependent hydrolases; chlorohydrolase/aminohydrolase 2416706 14294364 BPP43_11525 Brachyspira pilosicoli P43/6/78 chlorohydrolase/aminohydrolase YP_007235708.1 2415375 R 1042417 CDS YP_007235709.1 431808811 14294365 2416917..2417570 1 NC_019908.1 COG2964 Uncharacterized protein conserved in bacteria; hypothetical protein 2417570 14294365 BPP43_11530 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235709.1 2416917 D 1042417 CDS YP_007235710.1 431808812 14294366 2417563..2418756 1 NC_019908.1 COG1171 Threonine dehydratase; diaminopropionate ammonia-lyase 2418756 14294366 BPP43_11535 Brachyspira pilosicoli P43/6/78 diaminopropionate ammonia-lyase YP_007235710.1 2417563 D 1042417 CDS YP_007235711.1 431808813 14294367 2418796..2420127 1 NC_019908.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; peptidase 2420127 14294367 BPP43_11540 Brachyspira pilosicoli P43/6/78 peptidase YP_007235711.1 2418796 D 1042417 CDS YP_007235712.1 431808814 14294368 2420174..2421367 1 NC_019908.1 COG0078 Ornithine carbamoyltransferase; aspartate/ornithine carbamoyltransferase family protein 2421367 14294368 BPP43_11545 Brachyspira pilosicoli P43/6/78 aspartate/ornithine carbamoyltransferase family protein YP_007235712.1 2420174 D 1042417 CDS YP_007235713.1 431808815 14294369 2421497..2422438 1 NC_019908.1 COG0549 Carbamate kinase; amino acid kinase 2422438 14294369 BPP43_11550 Brachyspira pilosicoli P43/6/78 amino acid kinase YP_007235713.1 2421497 D 1042417 CDS YP_007235714.1 431808816 14294370 2422622..2424751 1 NC_019908.1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; CoxL protein 2424751 14294370 BPP43_11555 Brachyspira pilosicoli P43/6/78 CoxL protein YP_007235714.1 2422622 D 1042417 CDS YP_007235715.1 431808817 14294371 2424753..2425238 1 NC_019908.1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; CoxS protein 2425238 14294371 BPP43_11560 Brachyspira pilosicoli P43/6/78 CoxS protein YP_007235715.1 2424753 D 1042417 CDS YP_007235716.1 431808818 14294372 2425232..2426083 1 NC_019908.1 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; CoxM protein 2426083 14294372 BPP43_11565 Brachyspira pilosicoli P43/6/78 CoxM protein YP_007235716.1 2425232 D 1042417 CDS YP_007235717.1 431808819 14294373 2426123..2427502 1 NC_019908.1 COG2233 Xanthine/uracil permeases; uracil permease UraA 2427502 14294373 BPP43_11570 Brachyspira pilosicoli P43/6/78 uracil permease UraA YP_007235717.1 2426123 D 1042417 CDS YP_007235718.1 431808820 14294374 complement(2427544..2428521) 1 NC_019908.1 COG2068 Uncharacterized MobA-related protein; hypothetical protein 2428521 14294374 BPP43_11575 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235718.1 2427544 R 1042417 CDS YP_007235719.1 431808821 14294375 complement(2428657..2428737) 1 NC_019908.1 hypothetical protein 2428737 14294375 BPP43_11580 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235719.1 2428657 R 1042417 CDS YP_007235720.1 431808822 14294376 complement(2428739..2429605) 1 NC_019908.1 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; hypothetical protein 2429605 14294376 BPP43_11585 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235720.1 2428739 R 1042417 CDS YP_007235721.1 431808823 14294377 complement(2429716..2430927) 1 NC_019908.1 COG0426 Uncharacterized flavoproteins; flavoprotein 2430927 14294377 BPP43_11590 Brachyspira pilosicoli P43/6/78 flavoprotein YP_007235721.1 2429716 R 1042417 CDS YP_007235722.1 431808824 14294378 complement(2430982..2432907) 1 NC_019908.1 COG1960 Acyl-CoA dehydrogenases; short-chain specific acyl-CoA dehydrogenase 2432907 14294378 BPP43_11595 Brachyspira pilosicoli P43/6/78 short-chain specific acyl-CoA dehydrogenase YP_007235722.1 2430982 R 1042417 CDS YP_007235723.1 431808825 14294379 complement(2432960..2434309) 1 NC_019908.1 COG0427 Acetyl-CoA hydrolase; butyryl-CoA transferase 2434309 14294379 BPP43_11600 Brachyspira pilosicoli P43/6/78 butyryl-CoA transferase YP_007235723.1 2432960 R 1042417 CDS YP_007235724.1 431808826 14294380 complement(2435436..2436098) 1 NC_019908.1 hypothetical protein 2436098 14294380 BPP43_11615 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235724.1 2435436 R 1042417 CDS YP_007235725.1 431808827 14294381 2437719..2438495 1 NC_019908.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; 3-hydroxybutyryl-CoA dehydrogenase 2438495 14294381 BPP43_11630 Brachyspira pilosicoli P43/6/78 3-hydroxybutyryl-CoA dehydrogenase YP_007235725.1 2437719 D 1042417 CDS YP_007235726.1 431808828 14294382 2438557..2439396 1 NC_019908.1 COG1250 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA dehydrogenase 2439396 14294382 BPP43_11635 Brachyspira pilosicoli P43/6/78 3-hydroxybutyryl-CoA dehydrogenase YP_007235726.1 2438557 D 1042417 CDS YP_007235727.1 431808829 14294383 2439513..2439887 1 NC_019908.1 COG2346 Truncated hemoglobins; hypothetical protein 2439887 14294383 BPP43_11640 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235727.1 2439513 D 1042417 CDS YP_007235728.1 431808830 14294384 complement(2439934..2440371) 1 NC_019908.1 COG1846 Transcriptional regulators; transcriptional regulator 2440371 14294384 BPP43_11645 Brachyspira pilosicoli P43/6/78 transcriptional regulator YP_007235728.1 2439934 R 1042417 CDS YP_007235729.1 431808831 14294385 complement(2440452..2441282) 1 NC_019908.1 COG0491 Zn-dependent hydrolases, including glyoxylases; metallo-beta-lactamase 2441282 14294385 BPP43_11650 Brachyspira pilosicoli P43/6/78 metallo-beta-lactamase YP_007235729.1 2440452 R 1042417 CDS YP_007235730.1 431808832 14294386 2441462..2442628 1 NC_019908.1 COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 2442628 14294386 BPP43_11655 Brachyspira pilosicoli P43/6/78 ankyrin repeat-containing protein YP_007235730.1 2441462 D 1042417 CDS YP_007235731.1 431808833 14294387 2442759..2443481 1 NC_019908.1 hypothetical protein 2443481 14294387 BPP43_11660 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235731.1 2442759 D 1042417 CDS YP_007235732.1 431808834 14294388 2443622..2444959 1 NC_019908.1 COG0457 FOG: TPR repeat; hypothetical protein 2444959 14294388 BPP43_11665 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235732.1 2443622 D 1042417 CDS YP_007235733.1 431808835 14294389 2445233..2446177 1 NC_019908.1 hypothetical protein 2446177 14294389 BPP43_11670 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235733.1 2445233 D 1042417 CDS YP_007235734.1 431808836 14294390 2446303..2446431 1 NC_019908.1 hypothetical protein 2446431 14294390 BPP43_11675 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235734.1 2446303 D 1042417 CDS YP_007235735.1 431808837 14294391 2446579..2446854 1 NC_019908.1 hypothetical protein 2446854 14294391 BPP43_11680 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235735.1 2446579 D 1042417 CDS YP_007235736.1 431808838 14294392 2446881..2447633 1 NC_019908.1 COG0789 Predicted transcriptional regulators; hypothetical protein 2447633 14294392 BPP43_11685 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235736.1 2446881 D 1042417 CDS YP_007235737.1 431808839 14294393 2447775..2448065 1 NC_019908.1 hypothetical protein 2448065 14294393 BPP43_11690 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235737.1 2447775 D 1042417 CDS YP_007235738.1 431808840 14294394 2448136..2448759 1 NC_019908.1 COG0119 Isopropylmalate/homocitrate/citramalate synthases; hypothetical protein 2448759 14294394 BPP43_11695 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235738.1 2448136 D 1042417 CDS YP_007235739.1 431808841 14294395 2448740..2449756 1 NC_019908.1 hypothetical protein 2449756 14294395 BPP43_11700 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235739.1 2448740 D 1042417 CDS YP_007235740.1 431808842 14294396 2449924..2451513 1 NC_019908.1 COG1785 Alkaline phosphatase; alkaline protease 2451513 14294396 BPP43_11705 Brachyspira pilosicoli P43/6/78 alkaline protease YP_007235740.1 2449924 D 1042417 CDS YP_007235741.1 431808843 14294397 complement(2451570..2452877) 1 NC_019908.1 Na+-driven multidrug efflux pump 2452877 14294397 BPP43_11710 Brachyspira pilosicoli P43/6/78 Na+-driven multidrug efflux pump YP_007235741.1 2451570 R 1042417 CDS YP_007235742.1 431808844 14294398 2453165..2455255 1 NC_019908.1 COG0480 Translation elongation factors (GTPases); translation elongation factor G 2455255 14294398 BPP43_11715 Brachyspira pilosicoli P43/6/78 translation elongation factor G YP_007235742.1 2453165 D 1042417 CDS YP_007235743.1 431808845 14294399 2455335..2456153 1 NC_019908.1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein 2456153 14294399 BPP43_11720 Brachyspira pilosicoli P43/6/78 PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein YP_007235743.1 2455335 D 1042417 CDS YP_007235744.1 431808846 14294400 2456157..2456558 1 NC_019908.1 hypothetical protein 2456558 14294400 BPP43_11725 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235744.1 2456157 D 1042417 CDS YP_007235745.1 431808847 14294401 complement(2456842..2457873) 1 NC_019908.1 COG0232 dGTP triphosphohydrolase; deoxyguanosinetriphosphate triphosphohydrolase 2457873 14294401 BPP43_11730 Brachyspira pilosicoli P43/6/78 deoxyguanosinetriphosphate triphosphohydrolase YP_007235745.1 2456842 R 1042417 CDS YP_007235746.1 431808848 14294402 2458307..2458699 1 NC_019908.1 hypothetical protein 2458699 14294402 BPP43_11735 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235746.1 2458307 D 1042417 CDS YP_007235747.1 431808849 14294403 2458718..2459980 1 NC_019908.1 COG1519 3-deoxy-D-manno-octulosonic-acid transferase; 3-deoxy-D-manno-oct-2-ulosonic acid transferase 2459980 14294403 BPP43_11740 Brachyspira pilosicoli P43/6/78 3-deoxy-D-manno-oct-2-ulosonic acid transferase YP_007235747.1 2458718 D 1042417 CDS YP_007235748.1 431808850 14294404 complement(2459981..2461114) 1 NC_019908.1 COG0477 Permeases of the major facilitator superfamily; transporter 2461114 14294404 BPP43_11745 Brachyspira pilosicoli P43/6/78 transporter YP_007235748.1 2459981 R 1042417 CDS YP_007235749.1 431808851 14294405 complement(2461130..2461714) 1 NC_019908.1 COG0632 Holliday junction resolvasome, DNA-binding subunit; holliday junction DNA helicase RuvA 2461714 14294405 BPP43_11750 Brachyspira pilosicoli P43/6/78 holliday junction DNA helicase RuvA YP_007235749.1 2461130 R 1042417 CDS YP_007235750.1 431808852 14294406 complement(2461719..2461928) 1 NC_019908.1 COG2608 Copper chaperone; copper chaperone CopZ 2461928 14294406 BPP43_11755 Brachyspira pilosicoli P43/6/78 copper chaperone CopZ YP_007235750.1 2461719 R 1042417 CDS YP_007235751.1 431808853 14294407 complement(2462011..2463258) 1 NC_019908.1 COG1757 Na+/H+ antiporter; Na antiporter NhaC 2463258 14294407 BPP43_11760 Brachyspira pilosicoli P43/6/78 Na antiporter NhaC YP_007235751.1 2462011 R 1042417 CDS YP_007235752.1 431808854 14294408 2463257..2463460 1 NC_019908.1 hypothetical protein 2463460 14294408 BPP43_11765 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235752.1 2463257 D 1042417 CDS YP_007235753.1 431808855 14294409 2463630..2464853 1 NC_019908.1 hypothetical protein 2464853 14294409 BPP43_11770 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235753.1 2463630 D 1042417 CDS YP_007235754.1 431808856 14294410 2464901..2465443 1 NC_019908.1 COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein 2465443 14294410 BPP43_11775 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235754.1 2464901 D 1042417 CDS YP_007235755.1 431808857 14294411 complement(2465779..2467470) 1 NC_019908.1 COG3392 Adenine-specific DNA methylase; site-specific DNA-methyltransferase 2467470 14294411 BPP43_11780 Brachyspira pilosicoli P43/6/78 site-specific DNA-methyltransferase YP_007235755.1 2465779 R 1042417 CDS YP_007235756.1 431808858 14294412 2467573..2468643 1 NC_019908.1 COG2017 Galactose mutarotase and related enzymes; aldose-1-epimerase 2468643 14294412 BPP43_11785 Brachyspira pilosicoli P43/6/78 aldose-1-epimerase YP_007235756.1 2467573 D 1042417 CDS YP_007235757.1 431808859 14294413 complement(2469121..2469630) 1 NC_019908.1 COG4769 Predicted membrane protein; integral membrane protein 2469630 14294413 BPP43_11790 Brachyspira pilosicoli P43/6/78 integral membrane protein YP_007235757.1 2469121 R 1042417 CDS YP_007235758.1 431808860 14294414 complement(2469657..2470034) 1 NC_019908.1 hypothetical protein 2470034 14294414 BPP43_11795 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235758.1 2469657 R 1042417 CDS YP_007235759.1 431808861 14294415 complement(2470019..2470987) 1 NC_019908.1 COG4856 Uncharacterized protein conserved in bacteria; YbbR-like protein 2470987 14294415 BPP43_11800 Brachyspira pilosicoli P43/6/78 YbbR-like protein YP_007235759.1 2470019 R 1042417 CDS YP_007235760.1 431808862 14294416 complement(2470989..2471423) 1 NC_019908.1 COG1624 Uncharacterized conserved protein; hypothetical protein 2471423 14294416 BPP43_11805 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235760.1 2470989 R 1042417 CDS YP_007235761.1 431808863 14294417 2471851..2472519 1 NC_019908.1 hypothetical protein 2472519 14294417 BPP43_11810 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235761.1 2471851 D 1042417 CDS YP_007235762.1 431808864 14294418 2472542..2472937 1 NC_019908.1 COG0432 Uncharacterized conserved protein; hypothetical protein 2472937 14294418 BPP43_11815 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235762.1 2472542 D 1042417 CDS YP_007235763.1 431808865 14294419 complement(2473134..2473598) 1 NC_019908.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 2473598 14294419 BPP43_11820 Brachyspira pilosicoli P43/6/78 N-acetyltransferase GCN5 YP_007235763.1 2473134 R 1042417 CDS YP_007235764.1 431808866 14294420 complement(2473582..2473944) 1 NC_019908.1 hypothetical protein 2473944 14294420 BPP43_11825 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235764.1 2473582 R 1042417 CDS YP_007235765.1 431808867 14294421 complement(2474022..2474990) 1 NC_019908.1 COG0859 ADP-heptose:LPS heptosyltransferase; ADP-heptose-LPS-heptosyltransferase II 2474990 14294421 BPP43_11830 Brachyspira pilosicoli P43/6/78 ADP-heptose-LPS-heptosyltransferase II YP_007235765.1 2474022 R 1042417 CDS YP_007235766.1 431808868 14294422 complement(2474990..2475754) 1 NC_019908.1 hypothetical protein 2475754 14294422 BPP43_11835 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235766.1 2474990 R 1042417 CDS YP_007235767.1 431808869 14294423 complement(2475763..2476440) 1 NC_019908.1 COG0541 Signal recognition particle GTPase; ATP/GTP-binding protein 2476440 14294423 BPP43_11840 Brachyspira pilosicoli P43/6/78 ATP/GTP-binding protein YP_007235767.1 2475763 R 1042417 CDS YP_007235768.1 431808870 14294424 2476697..2477356 1 NC_019908.1 hypothetical protein 2477356 14294424 BPP43_11845 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235768.1 2476697 D 1042417 CDS YP_007235769.1 431808871 14294425 2477558..2477857 1 NC_019908.1 hypothetical protein 2477857 14294425 BPP43_11850 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235769.1 2477558 D 1042417 CDS YP_007235770.1 431808872 14294426 2477996..2479246 1 NC_019908.1 COG0849 Actin-like ATPase involved in cell division; actin like ATPase 2479246 14294426 BPP43_11855 Brachyspira pilosicoli P43/6/78 actin like ATPase YP_007235770.1 2477996 D 1042417 CDS YP_007235771.1 431808873 14294427 2479452..2480402 1 NC_019908.1 flagellar filament outer layer protein FlaA 2480402 14294427 BPP43_11860 Brachyspira pilosicoli P43/6/78 flagellar filament outer layer protein FlaA YP_007235771.1 2479452 D 1042417 CDS YP_007235772.1 431808874 14294428 2480516..2481079 1 NC_019908.1 COG1335 Amidases related to nicotinamidase; isochorismatase hydrolase 2481079 14294428 BPP43_11865 Brachyspira pilosicoli P43/6/78 isochorismatase hydrolase YP_007235772.1 2480516 D 1042417 CDS YP_007235773.1 431808875 14294429 2481107..2481865 1 NC_019908.1 COG0149 Triosephosphate isomerase; triose-phosphate isomerase 2481865 14294429 BPP43_11870 Brachyspira pilosicoli P43/6/78 triose-phosphate isomerase YP_007235773.1 2481107 D 1042417 CDS YP_007235774.1 431808876 14294430 2481968..2482999 1 NC_019908.1 dynein heavy chain 2482999 14294430 BPP43_11875 Brachyspira pilosicoli P43/6/78 dynein heavy chain YP_007235774.1 2481968 D 1042417 CDS YP_007235775.1 431808877 14294431 2483012..2483665 1 NC_019908.1 COG0177 Predicted EndoIII-related endonuclease; endonuclease III 2483665 14294431 BPP43_11880 Brachyspira pilosicoli P43/6/78 endonuclease III YP_007235775.1 2483012 D 1042417 CDS YP_007235776.1 431808878 14294432 complement(2483951..2485900) 1 NC_019908.1 COG1629 Outer membrane receptor proteins, mostly Fe transport; outer membrane receptor 2485900 14294432 BPP43_11885 Brachyspira pilosicoli P43/6/78 outer membrane receptor YP_007235776.1 2483951 R 1042417 CDS YP_007235777.1 431808879 14294433 complement(2485907..2486503) 1 NC_019908.1 hypothetical protein 2486503 14294433 BPP43_11890 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235777.1 2485907 R 1042417 CDS YP_007235778.1 431808880 14294434 2486854..2487897 1 NC_019908.1 hypothetical protein 2487897 14294434 BPP43_11895 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235778.1 2486854 D 1042417 CDS YP_007235779.1 431808881 14294435 2487881..2488408 1 NC_019908.1 COG1051 ADP-ribose pyrophosphatase; nudix hydrolase 2488408 14294435 BPP43_11900 Brachyspira pilosicoli P43/6/78 nudix hydrolase YP_007235779.1 2487881 D 1042417 CDS YP_007235780.1 431808882 14294436 2488414..2489295 1 NC_019908.1 hypothetical protein 2489295 14294436 BPP43_11905 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235780.1 2488414 D 1042417 CDS YP_007235781.1 431808883 14294437 2492988..2493989 1 NC_019908.1 COG4927 Predicted choloylglycine hydrolase; choloylglycine hydrolase 2493989 14294437 BPP43_11920 Brachyspira pilosicoli P43/6/78 choloylglycine hydrolase YP_007235781.1 2492988 D 1042417 CDS YP_007235782.1 431808884 14294438 2495758..2496090 1 NC_019908.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); anti sigma factor antagonist 2496090 14294438 BPP43_11925 Brachyspira pilosicoli P43/6/78 anti sigma factor antagonist YP_007235782.1 2495758 D 1042417 CDS YP_007235783.1 431808885 14294439 2496149..2503141 1 NC_019908.1 COG0823 Periplasmic component of the Tol biopolymer transport system; Tol transport system component 2503141 14294439 BPP43_11930 Brachyspira pilosicoli P43/6/78 Tol transport system component YP_007235783.1 2496149 D 1042417 CDS YP_007235784.1 431808886 14294440 2503267..2503563 1 NC_019908.1 COG2973 Trp operon repressor; Trp operon repressor 2503563 14294440 BPP43_11935 Brachyspira pilosicoli P43/6/78 Trp operon repressor YP_007235784.1 2503267 D 1042417 CDS YP_007235785.1 431808887 14294441 complement(2503558..2504610) 1 NC_019908.1 COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; coproporphyrinogen III oxidase 2504610 14294441 BPP43_11940 Brachyspira pilosicoli P43/6/78 coproporphyrinogen III oxidase YP_007235785.1 2503558 R 1042417 CDS YP_007235786.1 431808888 14294442 complement(2504685..2505539) 1 NC_019908.1 COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); DNA directed RNA polymerase sigma subunit 2505539 14294442 BPP43_11945 Brachyspira pilosicoli P43/6/78 DNA directed RNA polymerase sigma subunit YP_007235786.1 2504685 R 1042417 CDS YP_007235787.1 431808889 14294443 complement(2505557..2506837) 1 NC_019908.1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2506837 14294443 BPP43_11950 Brachyspira pilosicoli P43/6/78 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_007235787.1 2505557 R 1042417 CDS YP_007235788.1 431808890 14294444 complement(2507011..2507382) 1 NC_019908.1 COG1846 Transcriptional regulators; marR family transcriptional regulator 2507382 14294444 BPP43_11955 Brachyspira pilosicoli P43/6/78 marR family transcriptional regulator YP_007235788.1 2507011 R 1042417 CDS YP_007235789.1 431808891 14294445 2507596..2509215 1 NC_019908.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; acyl-CoA synthase 2509215 14294445 BPP43_11960 Brachyspira pilosicoli P43/6/78 acyl-CoA synthase YP_007235789.1 2507596 D 1042417 CDS YP_007235790.1 431808892 14294446 2509209..2510810 1 NC_019908.1 COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase; bifunctional acetyl-CoA:acetoacetyl-CoA transferase subunit alpha/beta 2510810 14294446 BPP43_11965 Brachyspira pilosicoli P43/6/78 bifunctional acetyl-CoA:acetoacetyl-CoA transferase subunit alpha/beta YP_007235790.1 2509209 D 1042417 CDS YP_007235791.1 431808893 14294447 2510813..2511556 1 NC_019908.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-ketoacyl-ACP reductase 2511556 fabG 14294447 fabG Brachyspira pilosicoli P43/6/78 3-ketoacyl-ACP reductase YP_007235791.1 2510813 D 1042417 CDS YP_007235792.1 431808894 14294448 2511587..2512768 1 NC_019908.1 COG0183 Acetyl-CoA acetyltransferase; acetyl-CoA acetyltransferase 2512768 14294448 BPP43_11975 Brachyspira pilosicoli P43/6/78 acetyl-CoA acetyltransferase YP_007235792.1 2511587 D 1042417 CDS YP_007235793.1 431808895 14294449 2513661..2513882 1 NC_019908.1 hypothetical protein 2513882 14294449 BPP43_11990 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235793.1 2513661 D 1042417 CDS YP_007235794.1 431808896 14294450 2513904..2515454 1 NC_019908.1 COG0591 Na+/proline symporter; sodium/pantothenate symporter 2515454 14294450 BPP43_11995 Brachyspira pilosicoli P43/6/78 sodium/pantothenate symporter YP_007235794.1 2513904 D 1042417 CDS YP_007235795.1 431808897 14294451 2515532..2516044 1 NC_019908.1 hypothetical protein 2516044 14294451 BPP43_12000 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235795.1 2515532 D 1042417 CDS YP_007235796.1 431808898 14294452 2516075..2517214 1 NC_019908.1 COG1929 Glycerate kinase; glycerate kinase 2517214 14294452 BPP43_12005 Brachyspira pilosicoli P43/6/78 glycerate kinase YP_007235796.1 2516075 D 1042417 CDS YP_007235797.1 431808899 14294453 2517545..2518753 1 NC_019908.1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; spore coat polysaccharide biosynthesis protein SpsC 2518753 14294453 BPP43_12010 Brachyspira pilosicoli P43/6/78 spore coat polysaccharide biosynthesis protein SpsC YP_007235797.1 2517545 D 1042417 CDS YP_007235798.1 431808900 14294454 2518951..2519865 1 NC_019908.1 COG1472 Beta-glucosidase-related glycosidases; beta-N-acetylglucosaminidase-like protein 2519865 14294454 BPP43_12015 Brachyspira pilosicoli P43/6/78 beta-N-acetylglucosaminidase-like protein YP_007235798.1 2518951 D 1042417 CDS YP_007235799.1 431808901 14294455 2519887..2520915 1 NC_019908.1 COG1472 Beta-glucosidase-related glycosidases; anhydromuramoyl-peptide exo-beta-N-acetylglucosaminidase 2520915 14294455 BPP43_12020 Brachyspira pilosicoli P43/6/78 anhydromuramoyl-peptide exo-beta-N-acetylglucosaminidase YP_007235799.1 2519887 D 1042417 CDS YP_007235800.1 431808902 14294456 complement(2520939..2521235) 1 NC_019908.1 hypothetical protein 2521235 14294456 BPP43_12025 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235800.1 2520939 R 1042417 CDS YP_007235801.1 431808903 14294457 complement(2521462..2522100) 1 NC_019908.1 COG3404 Methenyl tetrahydrofolate cyclohydrolase; formiminotransferase cyclodeaminase 2522100 14294457 BPP43_12030 Brachyspira pilosicoli P43/6/78 formiminotransferase cyclodeaminase YP_007235801.1 2521462 R 1042417 CDS YP_007235802.1 431808904 14294458 complement(2522974..2524101) 1 NC_019908.1 phage protein 2524101 14294458 BPP43_12035 Brachyspira pilosicoli P43/6/78 phage protein YP_007235802.1 2522974 R 1042417 CDS YP_007235803.1 431808905 14294459 2524367..2524798 1 NC_019908.1 hypothetical protein 2524798 14294459 BPP43_12040 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235803.1 2524367 D 1042417 CDS YP_007235804.1 431808906 14294460 complement(2524886..2525053) 1 NC_019908.1 hypothetical protein 2525053 14294460 BPP43_12045 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235804.1 2524886 R 1042417 CDS YP_007235805.1 431808907 14294461 complement(2525068..2526354) 1 NC_019908.1 COG0285 Folylpolyglutamate synthase; bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC 2526354 14294461 BPP43_12050 Brachyspira pilosicoli P43/6/78 bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC YP_007235805.1 2525068 R 1042417 CDS YP_007235806.1 431808908 14294462 2527203..2527583 1 NC_019908.1 COG0789 Predicted transcriptional regulators; merR family transcriptional regulator 2527583 14294462 BPP43_12055 Brachyspira pilosicoli P43/6/78 merR family transcriptional regulator YP_007235806.1 2527203 D 1042417 CDS YP_007235807.1 431808909 14294463 2527602..2528039 1 NC_019908.1 COG4925 Uncharacterized conserved protein; hypothetical protein 2528039 14294463 BPP43_12060 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235807.1 2527602 D 1042417 CDS YP_007235808.1 431808910 14294464 2528119..2528964 1 NC_019908.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; aldo/keto reductase family oxidoreductase 2528964 14294464 BPP43_12065 Brachyspira pilosicoli P43/6/78 aldo/keto reductase family oxidoreductase YP_007235808.1 2528119 D 1042417 CDS YP_007235809.1 431808911 14294465 2529190..2530077 1 NC_019908.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; oxidoreductase-aldo/keto reductase family protein 2530077 14294465 BPP43_12070 Brachyspira pilosicoli P43/6/78 oxidoreductase-aldo/keto reductase family protein YP_007235809.1 2529190 D 1042417 CDS YP_007235810.1 431808912 14294466 2531412..2531921 1 NC_019908.1 COG0716 Flavodoxins; flavodoxin 2531921 14294466 BPP43_12085 Brachyspira pilosicoli P43/6/78 flavodoxin YP_007235810.1 2531412 D 1042417 CDS YP_007235811.1 431808913 14294467 2532216..2532662 1 NC_019908.1 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; cupin domain-containing protein 2532662 14294467 BPP43_12090 Brachyspira pilosicoli P43/6/78 cupin domain-containing protein YP_007235811.1 2532216 D 1042417 CDS YP_007235812.1 431808914 14294468 complement(2532922..2533803) 1 NC_019908.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 2533803 14294468 BPP43_12095 Brachyspira pilosicoli P43/6/78 LysR family transcriptional regulator YP_007235812.1 2532922 R 1042417 CDS YP_007235813.1 431808915 14294469 2533949..2534134 1 NC_019908.1 hypothetical protein 2534134 14294469 BPP43_12100 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235813.1 2533949 D 1042417 CDS YP_007235814.1 431808916 14294470 complement(2534317..2534856) 1 NC_019908.1 COG0655 Multimeric flavodoxin WrbA; multimeric flavodoxin WrbA 2534856 14294470 BPP43_12105 Brachyspira pilosicoli P43/6/78 multimeric flavodoxin WrbA YP_007235814.1 2534317 R 1042417 CDS YP_007235815.1 431808917 14294471 2535098..2535520 1 NC_019908.1 COG4925 Uncharacterized conserved protein; hypothetical protein 2535520 14294471 BPP43_12110 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235815.1 2535098 D 1042417 CDS YP_007235816.1 431808918 14294472 2535556..2536113 1 NC_019908.1 COG0110 Acetyltransferase (isoleucine patch superfamily); maltose-O-acetyltransferase 2536113 14294472 BPP43_12115 Brachyspira pilosicoli P43/6/78 maltose-O-acetyltransferase YP_007235816.1 2535556 D 1042417 CDS YP_007235817.1 431808919 14294473 2536148..2536993 1 NC_019908.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; 2,5-diketo-d-gluconic acid reductase 2536993 14294473 BPP43_12120 Brachyspira pilosicoli P43/6/78 2,5-diketo-d-gluconic acid reductase YP_007235817.1 2536148 D 1042417 CDS YP_007235818.1 431808920 14294474 2537013..2537849 1 NC_019908.1 COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit; 4-carboxymuconolactone decarboxylase 2537849 14294474 BPP43_12125 Brachyspira pilosicoli P43/6/78 4-carboxymuconolactone decarboxylase YP_007235818.1 2537013 D 1042417 CDS YP_007235819.1 431808921 14294475 2537954..2538256 1 NC_019908.1 hypothetical protein 2538256 14294475 BPP43_12130 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235819.1 2537954 D 1042417 CDS YP_007235820.1 431808922 14294476 2538278..2538820 1 NC_019908.1 COG0716 Flavodoxins; flavodoxin 2538820 14294476 BPP43_12135 Brachyspira pilosicoli P43/6/78 flavodoxin YP_007235820.1 2538278 D 1042417 CDS YP_007235821.1 431808923 14294477 2538856..2539683 1 NC_019908.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 2539683 14294477 BPP43_12140 Brachyspira pilosicoli P43/6/78 short chain dehydrogenase YP_007235821.1 2538856 D 1042417 CDS YP_007235822.1 431808924 14294478 2539725..2540423 1 NC_019908.1 COG0716 Flavodoxins; flavodoxin 2540423 14294478 BPP43_12145 Brachyspira pilosicoli P43/6/78 flavodoxin YP_007235822.1 2539725 D 1042417 CDS YP_007235823.1 431808925 14294479 2541047..2541676 1 NC_019908.1 hypothetical protein 2541676 14294479 BPP43_12150 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235823.1 2541047 D 1042417 CDS YP_007235824.1 431808926 14294480 complement(2541683..2542612) 1 NC_019908.1 COG0524 Sugar kinases, ribokinase family; PfkB family carbohydrate kinase 2542612 14294480 BPP43_12155 Brachyspira pilosicoli P43/6/78 PfkB family carbohydrate kinase YP_007235824.1 2541683 R 1042417 CDS YP_007235825.1 431808927 14294481 2542726..2543271 1 NC_019908.1 COG0671 Membrane-associated phospholipid phosphatase; phosphoesterase 2543271 14294481 BPP43_12160 Brachyspira pilosicoli P43/6/78 phosphoesterase YP_007235825.1 2542726 D 1042417 CDS YP_007235826.1 431808928 14294482 2543444..2545396 1 NC_019908.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting protein 2545396 14294482 BPP43_12165 Brachyspira pilosicoli P43/6/78 methyl-accepting protein YP_007235826.1 2543444 D 1042417 CDS YP_007235827.1 431808929 14294483 2545798..2546706 1 NC_019908.1 hypothetical protein 2546706 14294483 BPP43_12170 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235827.1 2545798 D 1042417 CDS YP_007235828.1 431808930 14294484 2546717..2547157 1 NC_019908.1 hypothetical protein 2547157 14294484 BPP43_12175 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235828.1 2546717 D 1042417 CDS YP_007235829.1 431808931 14294485 complement(2547285..2548235) 1 NC_019908.1 COG0655 Multimeric flavodoxin WrbA; multimeric flavodoxin WrbA 2548235 14294485 BPP43_12180 Brachyspira pilosicoli P43/6/78 multimeric flavodoxin WrbA YP_007235829.1 2547285 R 1042417 CDS YP_007235830.1 431808932 14294486 complement(2548879..2550297) 1 NC_019908.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter substrate-binding protein 2550297 14294486 BPP43_12185 Brachyspira pilosicoli P43/6/78 oligopeptide ABC transporter substrate-binding protein YP_007235830.1 2548879 R 1042417 CDS YP_007235831.1 431808933 14294489 complement(2551755..2553161) 1 NC_019908.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; binding-protein-dependent transport system inner membrane protein 2553161 14294489 BPP43_12190 Brachyspira pilosicoli P43/6/78 binding-protein-dependent transport system inner membrane protein YP_007235831.1 2551755 R 1042417 CDS YP_007235832.1 431808934 14294491 complement(2553161..2554201) 1 NC_019908.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; binding-protein-dependent transport system inner membrane protein 2554201 14294491 BPP43_12195 Brachyspira pilosicoli P43/6/78 binding-protein-dependent transport system inner membrane protein YP_007235832.1 2553161 R 1042417 CDS YP_007235833.1 431808935 14294492 2554480..2555508 1 NC_019908.1 hypothetical protein 2555508 14294492 BPP43_12200 Brachyspira pilosicoli P43/6/78 hypothetical protein YP_007235833.1 2554480 D 1042417 CDS