-- dump date 20140619_001120 -- class Genbank::CDS -- table cds_note -- id note YP_001608483.1 homologous to ResP of plasmid R388 [Escherichia coli] ,InterPro; Resolvase N-terminal; hypothetical protein YP_001608484.1 partitioning protein ParA; hypothetical protein YP_001608486.1 homologous to Bacterial regulatory proteins, AsnC family [Nitrosomonas europaea ATCC 19718] ,homologous to Fic family protein [Wolbachia endosymbiont of Drosophila melanogaster],InterPro; Filamentation induced by cAMP protein Fic; hypothetical protein YP_001608487.1 homologous to RelE-like Cytotoxic translational repressor of toxin-antitoxin stability system [Azoarcus sp. EbN1]; hypothetical protein YP_001608488.1 homologous to putative HTH-type transcriptional regulator yiaG; hypothetical protein YP_001608496.1 homologous to helicase, putative/conserved hypothetical protein [Mycobacterium tuberculosis CDC1551],InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001608497.1 homologous to hypothetical Membrane Spanning Protein [Brucella melitensis 16M]; hypothetical protein YP_001608498.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1],homologous to virulence-associated protein E [Brucella melitensis 16M]; hypothetical protein YP_001608501.1 homologous to ATP/GTP-BINDING PROTEIN [Brucella melitensis 16M]; hypothetical protein YP_001608503.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001608504.1 CoaE; dephospho-CoA kinase (EC 2.7.1.24) (Dephosphocoenzyme A kinase),InterPro; catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001608506.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001608507.1 homologous to endonuclease/exonuclease/phosphatase family protein [Brucella abortus biovar 1 str. 9-941],InterPro; Endonuclease/exonuclease/phosphatase family; hypothetical protein YP_001608508.1 putative integral membrane protein,InterPro; Protein of unknown function UPF0005; hypothetical protein YP_001608509.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001608510.1 tRNA/rRNA methyltransferase, InterPro; tRNA/rRNA methyltransferase (SpoU); hypothetical protein YP_001608512.1 putative integral membrane protein; hypothetical protein YP_001608513.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001608516.1 InterPro: ABC transporter; hypothetical protein YP_001608517.1 2.7.1.69) YP_001608519.1 putative Fe-S-cluster redox enzyme, homologous to FLORFENICOL RESISTANCE PROTEIN [Brucella melitensis 16M] and to hypothetical UPF0063 protein YfgB of E. coli (P36979),InterPro; Conserved hypothetical protein 48; hypothetical protein YP_001608521.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001608522.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine YP_001608523.1 Peptide chain release factor 3 (RF-3),InterPro; Peptide chain release factor 3; hypothetical protein YP_001608525.1 InterPro; UvrD/REP helicase; hypothetical protein YP_001608526.1 Thioredoxin C-1,InterPro: Thioredoxin type domain; hypothetical protein YP_001608527.1 partial homology to putative ATPase or kinase;,similar to hypothetical UPF0079 protein yjeE in E. coli (P31805) ,InterPro; Protein of unknown function UPF0079; hypothetical protein YP_001608528.1 partial homology to putative ATPase or kinase;,similar to hypothetical UPF0079 protein yjeE in E. coli (P31805) ,InterPro; Protein of unknown function UPF0079; hypothetical protein YP_001608529.1 putative ATPase or kinase;,similar to hypothetical UPF0079 protein yjeE in E. coli (P31805) ,InterPro; Protein of unknown function UPF0079; hypothetical protein YP_001608531.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001608534.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001608535.1 putative role in sulfur assimilation YP_001608536.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; in the alphaproteobacteria, this protein contains an N-terminal SbtC-like domain YP_001608538.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001608539.1 negatively supercoils closed circular double-stranded DNA YP_001608541.1 homologous to predicted ATPase with chaperone activity [Mesorhizobium sp. BNC1] (ZP_00195626), and homologous to Competence protein comM (P45049) ,InterPro; Mg chelatase-related protein; hypothetical protein YP_001608544.1 homologous to Lipid A export ATP-binding protein msbA of Ralstonia (Pseudomonas) solanacearum (Q8XXB6) ,InterPro; ABC transporter transmembrane region; hypothetical protein YP_001608545.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001608547.1 InterPro; Protein of unknown function DUF45; hypothetical protein YP_001608548.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001608549.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001608550.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001608551.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001608552.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001608554.1 Phosphocarrier protein HPr (Histidine-containing protein) (Q87DQ0 in Xylella fastidiosa strain Temecula1),InterPro; Phosphocarrier HPr protein; hypothetical protein YP_001608556.1 homologous to Serine kinase HprK of the HPr protein of Brucella melitensis (regulates carbohydrate metabolism), and to sensor protein ChvG of Brucella melitensis hypothetical protein YP_001608558.1 homologous to transcriptional regulatory protein chvI of Agrobacterium tumefaciens (Q07783) ,InterPro; Response regulator receiver; hypothetical protein YP_001608559.1 homologous to unknown E. coli protein from 2D-page (Spot LM6) (P39169),InterPro; Transport-associated domain,Peptidoglycan-binding LysM; hypothetical protein YP_001608561.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001608562.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001608563.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001608565.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001608566.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001608568.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001608569.1 methionyl-tRNA formyltransferase(EC~2.1.2.9); InterPro YP_001608570.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001608574.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001608575.1 cytidylate kinase (EC 2.7.4.14); cytidine~ monophosphate kinase; InterPro; Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001608576.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001608577.1 beta (1-->2) glucan biosynthesis protein; beta-(1,2)-glucan production associated transmembrane protein; hypothetical protein YP_001608578.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001608580.1 inner-membrane protein (permease component) of an iron transport system,InterPro: ABC transporter family 3; hypothetical protein YP_001608581.1 inner-membrane protein (permease component) of an iron transport system,InterPro: ABC transporter family 3; hypothetical protein YP_001608582.1 ATP-binding component of an iron transport system,InterPro: ABC transporter; hypothetical protein YP_001608584.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001608585.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001608586.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001608591.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001608593.1 This protein performs the mismatch recognition step during the DNA repair process YP_001608594.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001608595.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001608596.1 conserved hypothetical (putative membrane) protein,partial similarity to FxsA protein of Serratia marcescens (Suppressor of F exclusion of phage T7) (Fragment) (P37148),InterPro; FxsA cytoplasmic membrane protein; hypothetical protein YP_001608598.1 homologous to Smr family protein [Brucella abortus biovar 1 str. 9-941],InterPro; Smr protein/MutS2 C-terminal; hypothetical protein YP_001608600.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001608603.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001608604.1 partly similar to replication protein [Pseudomonas syringae pv. maculicola]; hypothetical protein YP_001608605.1 homologous to Thiol:disulfide interchange protein cycY/ccmG precursor in Bradyrhizobium japonicum (Cytochrome c biogenesis protein cycY) (P30960),InterPro: Periplasmic protein thiol;disulfide oxidoreductase DsbE; hypothetical protein YP_001608606.1 weak similarity to Heme exporter protein D (CcmD) (PF04995); hypothetical protein YP_001608607.1 Heme exporter protein C (Cytochrome c-type biogenesis protein cycZ) (P30962 in Bradyrhizobium japonicum) with predicted signal peptide, putative permease component,InterPro; Cytochrome c-type biogenesis protein CcmC; hypothetical protein YP_001608608.1 Heme exporter protein B (Cytochrome c-type biogenesis protein cycW) (P30964 in Bradyrhizobium japonicum) with predicted signal peptide, putative permease component,InterPro; Cytochrome c-type biogenesis protein CcmB; hypothetical protein YP_001608609.1 ATP-binding protein; required for proper cytochrome c maturation YP_001608610.1 Catalyzes the conversion of citrate to isocitrate YP_001608611.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001608612.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001608613.1 binds the polymerase to DNA and acts as a sliding clamp YP_001608614.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001608615.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001608619.1 Cytochrome o ubiquinol oxidase cyoD ,InterPro; Prokaryotic Cytochrome C oxidase subunit IV; hypothetical protein YP_001608620.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001608621.1 similar to hypothetical integrase prophage protein [Brucella abortus biovar 1 str. 9-941]; hypothetical protein YP_001608622.1 similar to Sinorhizobium meliloti integrase; hypothetical protein YP_001608623.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001608624.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001608625.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001608626.1 Ferric uptake regulation protein (Ferric uptake regulator), homologous to irr of Agrobacterium tumefaciens (transcriptional regulator, Fur family),InterPro; Ferric-uptake regulator; hypothetical protein YP_001608628.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001608630.1 homologous to ACRIFLAVIN RESISTANCE PROTEIN AcrE [Brucella melitensis 16M],similar to Multidrug resistance protein MdtA precursor of E. coli (Multidrug transporter mdtA) (Q8X7J5), with predicted signal peptide; hypothetical protein YP_001608631.1 acriflavin resistance protein acrD, homologous to Multidrug resistance protein MdtC of Photorhabdus luminescens (subsp. laumondii) (Multidrug transporter MdtC) (Q7N3E1),InterPro; Acriflavin resistance protein; hypothetical protein YP_001608632.1 glucose-6-phosphate isomerase (EC 5.3.1.9); phosphoglucose isomerase; phosphohexose isomerase (PHI) (Q8L1Z9 in Bartonella henselae),InterPro; functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001608634.1 involved in the peptidyltransferase reaction during translation YP_001608637.1 hypothetical protein with predicted TMH (six);,weak similarity with transport permeases; hypothetical protein YP_001608638.1 hypothetical protein with predicted TMH (six) and a signal peptide; hypothetical protein YP_001608639.1 hypothetical prophage integrase,InterPro; Phage integrase; hypothetical protein YP_001608640.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; predicted transcriptional regulator; hypothetical protein YP_001608643.1 InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001608644.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608645.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608646.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608651.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001608652.1 glutamate 5-kinase (EC 2.7.2.11); gamma-glutamyl kinase,InterPro; aspartate/glutamate/uridylate kinase; catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001608653.1 gamma-glutamyl phosphate reductase (EC~ 1.2.1.41); glutamate-5-semialdehyde dehydrogenase; InterPro; Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001608654.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001608655.1 Uncharacterized homolog of plant Iojap protein,InterPro; Iojap-related protein; hypothetical protein YP_001608656.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001608657.1 Region start changed from 232177 to 232123 (54 bases) YP_001608659.1 hydrolyzes diadenosine polyphosphate YP_001608661.1 Predicted integral membrane protein,InterPro; Protein of unknown function YGGT; hypothetical protein YP_001608662.1 InterPro; Protein of unknown function DUF167; hypothetical protein YP_001608663.1 inorganic pyrophosphatase (EC 3.6.1.1); pyrophosphate phospho-hydrolase,InterPro; catalyzes the hydrolysis of pyrophosphate to phosphate YP_001608665.1 Mg2+ transporter containing CBS domains,InterPro; Divalent cation transporter; hypothetical protein YP_001608666.1 InterPro: Peptidase M3; hypothetical protein YP_001608667.1 similar to hypothetical cytosolic protein [Brucella melitensis 16M]; hypothetical protein YP_001608672.1 homologous to sigma-54 dependent DNA-binding response regulator [Brucella suis 1330],InterPro; Sigma-54 factor interaction domain; hypothetical protein YP_001608673.1 homologous to phospholipase D family protein [Agrobacterium tumefaciens str. C58] and to hosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes,InterPro; Phospholipase D/Transphosphatidylase; hypothetical protein YP_001608674.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001608676.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001608678.1 Glycerol-3-phosphate-binding periplasmic protein precursor (ABC transporter); ,homologous to probable arabinose-binding protein precursor of Bacillus subtilis (P94528),InterPro; Bacterial extracellular solute-binding protein family 1; hypothetical protein YP_001608679.1 SN-glycerol-3-phosphate transport system permease ugpA (P10905) ,weak similarity to hypothetical ABC transporter permease protein yurN of Bacillus subtilis (O32155),InterPro; Binding-protein-dependent transport systems inner membrane component; hypothetical protein YP_001608680.1 SN-glycerol-3-phosphate transport system permease ugpE of E.coli (P10906) ,InterPro; Binding-protein-dependent transport systems inner membrane component; hypothetical protein YP_001608681.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001608682.1 putative ABC-type metal ion transport system,periplasmic component/surface adhesin,InterPro; Periplasmic solute binding protein; hypothetical protein YP_001608683.1 InterPro: ABC transporter family 3; hypothetical protein YP_001608684.1 homologous to Manganese transport system ATP-binding protein mntB of Bacillus subtilis (Q92AF9) ,InterPro: ABC transporter; hypothetical protein YP_001608685.1 Glutaredoxin-like protein nrdH (Q92AF9); hypothetical protein YP_001608686.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_001608687.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001608688.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001608690.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001608691.1 Ferric uptake regulation protein (Ferric uptake regulator), iron response regulator,InterPro; Ferric-uptake regulator; hypothetical protein YP_001608692.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001608694.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001608697.1 putative phage integrase; hypothetical protein YP_001608698.1 homologous to cell wall-associated hydrolases (invasion-associated proteins) [Mesorhizobium sp. BNC1],homologous GAMMA-D-GLUTAMYL-L-DIAMINO ACID ENDOPEPTIDASE II [Brucella melitensis 16M],InterPro; NLP/P60; hypothetical protein YP_001608700.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001608702.1 heat shock protein involved in degradation of misfolded proteins YP_001608703.1 heat shock protein involved in degradation of misfolded proteins YP_001608706.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001608708.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001608709.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001608710.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001608711.1 Predicted nucleic-acid-binding protein implicated in transcription termination. InterPro; Protein of unknown function DUF448; hypothetical protein YP_001608712.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001608713.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001608714.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001608715.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001608717.1 apolipoprotein N-acyltransferase (EC 2.3.1.-); Transfers the fatty acyl group on membrane lipoproteins YP_001608718.1 homologous to Hemolysin tlyC of Rickettsia prowazekii and to putative magnesium and cobalt efflux protein corC of E.coli (P77392),InterPro; Transporter associated domain; hypothetical protein YP_001608719.1 homologous to DIACYGLYCEROL KINASE [Brucella melitensis 16M],InterPro; Protein of unknown function UPF0054; hypothetical protein YP_001608720.1 Phosphate starvation-inducible protein PhoH,predicted ATPase,InterPro; PhoH-like protein; hypothetical protein YP_001608721.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001608723.1 homologous to putative protease [Brucella suis 1330] and to hypothetical M22 peptidase homolog yeaZ of E.coli (P76256),InterPro; Peptidase M22 glycoprotease metalloprotease; hypothetical protein YP_001608724.1 Putative membrane protein (Q6G4V3 in Bartonella henselae) ,InterPro; Conserved hypothetical protein 698; hypothetical protein YP_001608725.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001608726.1 InterPro; Conserved hypothetical protein 103; hypothetical protein YP_001608727.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001608729.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001608730.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001608732.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001608733.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001608734.1 homologous to phosphate ABC transporterphosphate-binding protein [Brucella abortus biovar 1 str. 9-941]; hypothetical protein YP_001608735.1 InterPro; Binding-protein-dependent transport systems inner membrane component; hypothetical protein YP_001608736.1 InterPro; Binding-protein-dependent transport systems inner membrane component; hypothetical protein YP_001608737.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001608738.1 Phosphate transport system protein phoU (Q52989 in Sinorhizobium meliloti) ;,homologous to phosphate transport system regulatory protein PhoU [Brucella abortus biovar 1 str. 9-941],InterPro; PhoU; hypothetical protein YP_001608741.1 formamidopyrimidine-DNA glycosylase (EC 3.2.2.23); Fapy-DNA glycosylase; DNA-(apurinic or apyrimidinic site) lyase; mutM (EC 4.2.99.18); AP lyase mutM (P05523~ in E. coli); Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001608747.1 isoleucyl-tRNA synthetase (EC 6.1.1.5); isoleucine--tRNA ligase; isoleucyl-tRNA synthetase class Ia; IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme YP_001608756.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001608757.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001608759.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001608760.1 Catalyzes the deamination of dCTP to form dUTP YP_001608761.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_001608762.1 putative Integrase; hypothetical protein YP_001608763.1 hypothetical phage integrase; hypothetical protein YP_001608764.1 hypothetical genomic island protein; hypothetical protein YP_001608766.1 homologous to site-specific DNA methylase [Rhodobacter sphaeroides 2.4.1]; homologous to Dam modification methylase [Bacteriophage B3]; hypothetical protein YP_001608767.1 hypothetical phage integrase;,homologous to prophage CP4-57 integrase of E.coli (P32053),InterPro; Phage integrase; hypothetical protein YP_001608770.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1];,homologous to hypothetical protein yafQ of E. coli (Q47149),InterPro; Conserved hypothetical protein 53; hypothetical protein YP_001608772.1 hypothetical prophage protein with predicted signal peptide;,homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608775.1 putative transcriptional regulator with predicted nucleic acid binding motif (HTH); hypothetical protein YP_001608776.1 homologous to late control gene D protein (GpD) of Bacteriophage 186 (P21679); hypothetical protein YP_001608778.1 phage tail protein U; hypothetical protein YP_001608779.1 homologous to phage tail protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608781.1 Major tail tube protein FII;,homologous to major tail tube protein of Bacteriophage P2 (Protein FII) (P22502); hypothetical protein YP_001608782.1 major tail sheath protein FI,homologous to major tail sheath protein (Protein FI) of Bacteriophage P2 (P22501),InterPro; Phage tail sheath protein; hypothetical protein YP_001608783.1 phage anti-repressor protein;,partially similar to Hypothetical protein HI1422 of Haemophilus influenzae (P44193); hypothetical protein YP_001608791.1 phage protein gp26; baseplate assembly protein J (GpJ),InterPro; Baseplate J-like protein; hypothetical protein YP_001608792.1 Phage protein gp25; baseplate assembly protein W (GpW),InterPro; GPW/gp25 family; hypothetical protein YP_001608793.1 Region start changed from 396514 to 396448 (-66 bases) YP_001608795.1 Region start changed from 397055 to 397025 (30 bases) YP_001608798.1 fragmented anti-repressor gene (C-terminal fragment); hypothetical protein YP_001608799.1 fragmented anti-repressor gene (N-terminal fragment); hypothetical protein YP_001608800.1 hypothetical prophage integral membrane protein; hypothetical protein YP_001608802.1 homologous to BH03280; hypothetical protein YP_001608805.1 phage protein gp18; homologous to minor capsid protein C of Bacteriophage lambda (GPC) [Contains: Capsid assembly protein NU3](P03711); homologous to periplasmic serine proteases (ClpP class) ,InterPro: Peptidase U7; hypothetical protein YP_001608806.1 phage protein gp17; weak homology to portal protein (GPB) (Minor capsid protein B) of Bacteriophage lambda (P03710) ,InterPro; Phage portal protein lambda family; hypothetical protein YP_001608810.1 InterPro; Protein of unknown function DUF497; hypothetical protein YP_001608813.1 partially similar to hypothetical protein HI1412 of Haemophilus influenzae (P45197); hypothetical protein YP_001608816.1 homologous putative HTH-type transcriptional regulator ydcQ of Escherichia coli O157:H7 (P67698)(ydcQ); hypothetical protein YP_001608818.1 Single-strand binding protein (SSB) (Helix-destabilizing protein) (Q8YHC2 in Brucella melitensis),InterPro; Peptide chain release factor 1; hypothetical protein YP_001608821.1 putative membrane protein; hypothetical protein YP_001608823.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1] and to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608824.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1] and to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608825.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608827.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608828.1 similar to putative phage-related protein [Erwinia carotovora subsp. atroseptica SCRI1043]; hypothetical protein YP_001608829.1 phage anti-repressor protein;,partially similar to Hypothetical protein HI1422 of Haemophilus influenzae (P44193); hypothetical protein YP_001608830.1 homologous to putative antirepressor protein AntB [Bacteriophage Aaphi23];,homologous to Hypothetical protein HI1422 of Haemophilus influenzae (P44193); hypothetical protein YP_001608831.1 similar to Orf52 [Pseudomonas phage D3],InterPro; ERF; hypothetical protein YP_001608833.1 homologous to phage related protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608834.1 homologous to SlyX homolog of Brucella melitensis (Q8YDE6) ,InterPro; SlyX; hypothetical protein YP_001608835.1 very weak similarity to integrases; hypothetical protein YP_001608836.1 weakly conserved in alpha-proteobacteria; homologous to BH02740 and BQ02680; hypothetical protein YP_001608837.1 homologous to phenylalanine-specific permease aroP of E. coli (P24207) ,InterPro; Amino acid permease-associated region; hypothetical protein YP_001608838.1 Cobalt import ATP-binding protein CbiO (Q6G4Q8 in Bartonella henselae) ,InterPro: ABC transporter; hypothetical protein YP_001608839.1 homology to hypothetical protein BH02770 [Bartonella henselae str. Houston-1]; putative cobalt transport system permease protein,InterPro; Cobalt transport protein; hypothetical protein YP_001608840.1 conserved hypothetical membrane protein with predicted signal peptide;,putative biotin synthase bioY,InterPro; BioY protein; hypothetical protein YP_001608841.1 conserved hypothetical membrane protein with predicted signal peptide;,putative biotin synthase bioY,InterPro; BioY protein; hypothetical protein YP_001608842.1 very weak similarity to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19]; hypothetical protein YP_001608844.1 C-terminal homology to other B. tribocorum helicase/methyltransferases;,partial similarity to hypothetical protein BH15450 [Bartonella henselae str. Houston-1];,partial similarity to helicase domain protein (Pseudomonas syringae); hypothetical protein YP_001608845.1 homologous to hemolysin activator protein Hec [Bartonella henselae str. Houston-1];,homologous to hemolysin activator protein precursor HlyB of Serratia marcescens (P15321),InterPro; Hemolysin activator HlyB; hypothetical protein YP_001608847.1 Similarity to genomic island Orf7 of Photorhabdus luminescens (GenBank (NCBI Entrez)); hypothetical protein YP_001608849.1 Partial similarity to Rhs (recombinational hot spot) of Photorhabdus luminescens (GenBank (NCBI Entrez)); hypothetical protein YP_001608850.1 Similarity to genomic island Orf7 of Photorhabdus luminescens (GenBank (NCBI Entrez)); hypothetical protein YP_001608851.1 Similarity to genomic island Orf7 of Photorhabdus luminescens (GenBank (NCBI Entrez)); hypothetical protein YP_001608852.1 Similarity to genomic island Orf7 of Photorhabdus luminescens (GenBank (NCBI Entrez)); hypothetical protein YP_001608853.1 Similarity to genomic island Orf7 of Photorhabdus luminescens (GenBank (NCBI Entrez)); hypothetical protein YP_001608854.1 Partial similarity to Rhs (recombinational hot spot) of Photorhabdus luminescens (GenBank (NCBI Entrez)); hypothetical protein YP_001608858.1 partial similarity with large exoproteins involved in heme utilization or adhesion; hypothetical protein YP_001608859.1 N-terminal homology to other B. tribocorum helicase/methyltransferases; hypothetical protein YP_001608860.1 Hemolysin activator protein precursor; homologous to hemolysin activator protein, HlyB family (Pseudomonas syringae pv. tomato str. DC3000),NP_793015.1, 28870396 and to hemolysin activator-like protein fhaC precursor of Bordetella pertussis,InterPro; Hemolysin activator HlyB; hypothetical protein YP_001608862.1 homologous to hypothetical genomic island protein BH06700 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608864.1 homologous to hypothetical genomic island protein BH07170 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608866.1 homologous to hypothetical genomic island protein BH07160 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608871.1 homologous to hypothetical genomic island protein BH07250 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608872.1 homologous to proteic killer suppression protein [Bartonella henselae str. Houston-1];,homologous to proteic killer protein, putative [Pseudomonas syringae pv. tomato str. DC3000],InterPro; Plasmid maintenance system killer; hypothetical protein YP_001608874.1 phage-related integrase,InterPro; Phage integrase; hypothetical protein YP_001608875.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608877.1 similar to Orf52 [Pseudomonas phage D3],InterPro; ERF; hypothetical protein YP_001608878.1 homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19];,weak similarity to hypothetical protein ydcK of E. coli (P76100),InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608879.1 homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19];,weak similarity to hypothetical protein ydcK of E. coli (P76100),InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608880.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608881.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608882.1 partially similar to hypothetical protein HI1412 of Haemophilus influenzae (P45197); hypothetical protein YP_001608884.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608886.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608887.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1] and to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608888.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608893.1 Single-strand binding protein (SSB) (Helix-destabilizing protein) (Q8YHC2 in Brucella melitensis),InterPro; Single-strand binding protein; hypothetical protein YP_001608894.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1];,homologous to hypothetical protein in Brucella melitensis (BMEI1008, KEGG); hypothetical protein YP_001608895.1 Protein PemI (P13975 in E. coli) with predicted signal peptide,InterPro; SpoVT/AbrB-like domain; hypothetical protein YP_001608896.1 Protein pemK (P13976 in E.coli) ,InterPro; PemK-like protein; hypothetical protein YP_001608897.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1];,homologous to anti-toxin protein of Xylella fastidiosa (PD1183, KEGG); hypothetical protein YP_001608898.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1];,homologous to toxin-like protein of Xylella fastidiosa (PD1184, KEGG); hypothetical protein YP_001608899.1 homologous to BH09430; hypothetical protein YP_001608900.1 putative membrane protein with predicted signal peptide; hypothetical protein YP_001608901.1 homologous to BH09410; hypothetical protein YP_001608902.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608903.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608904.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608905.1 InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001608906.1 N-terminal homology to other B. tribocorum helicase/methyltransferases; hypothetical protein YP_001608907.1 similar to hypothetical membrane spanning protein [Brucella melitensis 16M];,weak similarity to hypothetical protein yfjI of E.coli (P52124); hypothetical protein YP_001608908.1 hypothetical genomic island protein; homologous to virulence-associated protein E [Brucella melitensis 16M]; hypothetical protein YP_001608909.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; with reporting nucleic acid binding motif; predicted transcriptional regulator; hypothetical protein YP_001608911.1 hypothetical prophage integrase,InterPro; Phage integrase; hypothetical protein YP_001608912.1 similar to terminase [Zymomonas mobilis subsp. mobilis ZM4]; hypothetical protein YP_001608913.1 partly similar to portal protein (Protein gp1) of bacteriophage P22 (P26744); hypothetical protein YP_001608914.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1](Q7VJY3) Chaperone clpB; hypothetical protein YP_001608915.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608916.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608917.1 homlogous to hypothetical genomic island protein; hypothetical protein YP_001608918.1 homologous to hypothetical genomic island protein; hypothetical protein YP_001608920.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608921.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608922.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608924.1 hypothetical prophage integrase,InterPro; Phage integrase; hypothetical protein YP_001608926.1 phage anti-repressor protein;,partially similar to Hypothetical protein HI1422 of Haemophilus influenzae (P44193); hypothetical protein YP_001608929.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1];,homologous to hypothetical protein yafQ of E. coli (Q47149),InterPro; Conserved hypothetical protein 53; hypothetical protein YP_001608933.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1];,homologous to hypothetical protein HI1419 of Haemophilus influenzae (P44190); hypothetical protein YP_001608936.1 weakly similar to hypothetical protein HI1412 of Haemophilus influenzae (P45197); hypothetical protein YP_001608937.1 homologous to late control gene D protein (GpD) of Bacteriophage 186 (P21679); hypothetical protein YP_001608938.1 Phage tail protein X (GpX),InterPro; Phage tail X; hypothetical protein YP_001608939.1 phage tail protein U; hypothetical protein YP_001608940.1 homologous to phage tail protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608941.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608942.1 Major tail tube protein FII,homologous to major tail tube protein pf Bacteriophage P2 (Protein FII) (P22502) ,InterPro; Phage major tail tube protein; hypothetical protein YP_001608943.1 major tail sheath protein FI,homologous to major tail sheath protein (Protein FI) of Bacteriophage P2 (P22501),InterPro; Phage tail sheath protein; hypothetical protein YP_001608944.1 phage anti-repressor protein;,partially similar to Hypothetical protein HI1422 of Haemophilus influenzae (P44193); hypothetical protein YP_001608945.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608947.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1];,homologous to putative proteic killer suppression protein {plasmid Rts1) [Rhodopseudomonas palustris CGA009],InterPro; Plasmid maintenance system killer; hypothetical protein YP_001608948.1 homologous to hypothetical 9.9 kDa protein y4eA of Rhizobium sp. (P55424),InterPro; Prevent-host-death family protein; hypothetical protein YP_001608956.1 phage protein gp26; baseplate assembly protein J (GpJ),InterPro; Baseplate J-like protein; hypothetical protein YP_001608957.1 Phage protein gp25; baseplate assembly protein W (GpW),InterPro; GPW/gp25 family; hypothetical protein YP_001608964.1 InterPro; Protein of unknown function DUF497; hypothetical protein YP_001608968.1 phage protein gp18; homologous to minor capsid protein C of Bacteriophage lambda (GPC) [Contains: Capsid assembly protein NU3](P03711); homologous to periplasmic serine proteases (ClpP class) ,InterPro: Peptidase U7; hypothetical protein YP_001608969.1 phage protein gp17; weak homology to portal protein (GPB) (Minor capsid protein B) of Bacteriophage lambda (P03710) ,InterPro; Phage portal protein lambda family; hypothetical protein YP_001608973.1 homologous to CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti]; hypothetical protein YP_001608974.1 homologous to HYPOTHETICAL PROTEIN [Sinorhizobium meliloti];,partially similar to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608976.1 partially similar to hypothetical protein HI1412 of Haemophilus influenzae (P45197); hypothetical protein YP_001608979.1 homologous to putative HTH-type transcriptional regulator ydcQ of Escherichia coli O157:H7; HTH cro/C1-type DNA-binding domain protein; hypothetical protein YP_001608981.1 hypothetical prophage integrase,InterPro; Phage integrase; hypothetical protein YP_001608982.1 Predicted transcriptional regulator; hypothetical protein YP_001608983.1 homologous to putative yacA [Plasmid ColIb-P9] [Nitrosomonas europaea ATCC 19718] and to YacA [Xanthomonas citri]; hypothetical protein YP_001608984.1 homology to putative plasmid stabilization system proteins,InterPro; Plasmid stabilization system; hypothetical protein YP_001608987.1 InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001608988.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608989.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608990.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001608991.1 Single-strand binding protein (SSB) (Helix-destabilizing protein) (Q8YHC2 in Brucella melitensis),InterPro; Single-strand binding protein; hypothetical protein YP_001608993.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608994.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1] and to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608995.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001608996.1 homologous to BH03630; hypothetical protein YP_001608997.1 similar to repressor protein CI of phage lambda (P03034); hypothetical protein YP_001608998.1 InterPro: Protein of unknown function DUF450; hypothetical protein YP_001608999.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609000.1 similar to putative phage-related protein [Erwinia carotovora subsp. atroseptica SCRI1043]; hypothetical protein YP_001609001.1 phage anti-repressor protein;,partially similar to Hypothetical protein HI1422 of Haemophilus influenzae (P44193); hypothetical protein YP_001609002.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609003.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609004.1 homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19];,weak similarity to hypothetical protein ydcK of E. coli (P76100),InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609005.1 homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19];,homologous to hypothetical protein ydcK of E. coli (P76100),InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609006.1 similar to Orf52 [Pseudomonas phage D3],InterPro; ERF; hypothetical protein YP_001609008.1 homologous to phage related protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609009.1 phosphoserine aminotransferase (EC 2.6.1.52); phosphoserine aminotransferase Methanosarcina type; catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate YP_001609010.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001609012.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001609015.1 InterPro; Cell divisionFtsK/SpoIIIE protein; hypothetical protein YP_001609017.1 homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001609018.1 dihydroorotate dehydrogenase (EC 1.3.3.1); dihydroorotate oxidase; dihydroorotate dehydrogenase 2; catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001609020.1 hypothetical protein with nine predicted TMH; hypothetical protein YP_001609021.1 hypothetical protein with nine predicted TMH; hypothetical protein YP_001609022.1 hypothetical protein with seven predicted TMH; hypothetical protein YP_001609023.1 hypothetical protein with nine predicted TMH; hypothetical protein YP_001609024.1 hypothetical protein with nine predicted TMH; hypothetical protein YP_001609025.1 hypothetical protein with four predicted TMH; hypothetical protein YP_001609027.1 putative transporter with 12 predicted TMH and a predicted signal peptide;,homologous to antibiotic efflux protein [Silicibacter pomeroyi DSS-3]; hypothetical protein YP_001609028.1 partially similar to oxygen-independent coproporphyrinogen III oxidase, putative [Coxiella burnetii RSA 493] and [Neisseria meningitidis Z2491],InterPro; Elongator protein 3/MiaB/NifB; hypothetical protein YP_001609029.1 putative permease with 11 predicted TMH;,homologous to possible MFS Superfamliy multidrug-efflux transporter [Yersinia pseudotuberculosis IP 32953];,homologous to mccC [Escherichia coli] (EMBL (EBI));,weakly similar to mccC [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609034.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001609036.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001609037.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001609038.1 homologous to asmA protein, assembly of outermembrane proteins [Mesorhizobium loti MAFF303099] ,InterPro; AsmA; hypothetical protein YP_001609039.1 hypothetical protein with predicted signal peptide; hypothetical protein YP_001609040.2 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001609042.1 hypothetical symporter; bifunctional: putative transport protein (N-terminal); putative kinase (C-terminal) [Escherichia coli K12],InterPro: Sodium;dicarboxylate symporter; hypothetical protein YP_001609043.1 homologous to BIOTIN SYNTHESIS PROTEIN BioC [Brucella melitensis 16M];,homologous to methyltransferase [Agrobacterium tumefaciens str. C58]; hypothetical protein YP_001609045.1 InterPro; Glutaredoxin; hypothetical protein YP_001609046.1 Involved in ubiquinone biosynthesis YP_001609047.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001609049.1 Na(+)/H(+) antiporter 1 (Sodium/proton antiporter 1),InterPro; Na+/H+ antiporter NhaA; hypothetical protein YP_001609051.1 putative transporter;,homologous to transporterTrkA family [Brucella abortus biovar 1 str. 9-941],InterPro; TrkA-C; hypothetical protein YP_001609052.1 homologous to hypothetical membrane associated protein [Brucella melitensis 16M]; hypothetical protein YP_001609053.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001609055.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001609056.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001609057.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel. YP_001609058.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001609059.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001609060.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001609061.1 hypothetical protein with predicted TPR domain (tetratricopeptide repeat domain),InterPro: TPR repeat; hypothetical protein YP_001609065.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001609066.1 homologous to Ribonuclease HII of Brucella melitensis (EC 3.1.26.4) (P0A4D9); RNase HII (P0A4D9); ribonuclease HII/HIII; RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001609067.1 homologous to hypothetical protein ywlC of Bacillus subtilis (P39153) and to Sua5/YciO/YrdC family protein [Brucella abortus biovar 1 str. 9-941],InterPro; Sua5/YciO/YrdC/YwlC; hypothetical protein YP_001609070.1 phosphoribosylamine--glycine ligase (EC 6.3.4.13); glycinamide ribonucleotide synthetase; phosphoribosylglycinamide synthetase; catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001609071.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_001609072.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001609073.1 InterPro; Chaperone DnaJ C-terminal; hypothetical protein YP_001609074.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001609075.1 chorismate synthase (EC 4.2.3.5); 5-enolpyruvylshikimate-3-phosphate phospholyase; catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001609077.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001609078.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001609082.1 weak similarity to invasion associated locus B [Agrobacterium tumefaciens str. C58]; hypothetical protein YP_001609083.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001609084.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001609085.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine YP_001609086.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001609088.1 putative transcriptional regulator;,homologous to TRANSCRIPTIONAL REGULATOR, AlgH [Brucella melitensis 16M],InterPro; Protein of unknown function DUF179; hypothetical protein YP_001609089.1 weakly similar to integrase; hypothetical protein YP_001609090.1 GGDEF domain, EAL domain, PAS/PAC domain protein with predicted TMH (seven) and signal peptide;,homologous to sensory box/GGDEF domain/EAL domain protein [Brucella suis 1330],InterPro; EAL domain; hypothetical protein YP_001609091.1 homologous to zinc protease [Brucella melitensis 16M],InterPro: Peptidase M16 inactive; hypothetical protein YP_001609092.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001609096.1 putative phosphatase;,homologous to PHOSPHOGLYCOLATE PHOSPHATASE [Brucella melitensis 16M];,homologous to hydrolase,haloacid dehalogenase-like family [Brucella suis 1330] ,InterPro; Haloacid dehalogenase-like hydrolase; hypothetical protein YP_001609097.1 homologous to BabI, modification methylase BabI (Adenine-specific methyltransferase BabI) (M.BabI) (M.CcrMI) [Brucella abortus biovar 1 str. 9-941],InterPro; DNA methylase N-4/N-6; hypothetical protein YP_001609100.1 homologous to twin-arginine translocation signal domain protein [Brucella abortus biovar 1 str. 9-941],InterPro; DSBA oxidoreductase; hypothetical protein YP_001609101.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001609104.1 homologous to cysteine desulfuration protein sufE of E. coli (P76194),InterPro: Protein of unknown function UPF0050; hypothetical protein YP_001609106.1 protease II (EC 3.4.21.83); pligopeptidase B; peptidase S9 prolyl oligopeptidase N-terminal beta-propeller domain YP_001609108.1 putative integrase; hypothetical protein YP_001609109.1 homologous to PUTATIVE TOXIN-ACTIVATING LYSINE-ACYLTRANSFERASE PROTEIN [Sinorhizobium meliloti];,homologous to Cytolysin-activating lysine-acyltransferase RtxC [Photorhabdus luminescens subsp. laumondii TTO1],InterPro; Bacterial RTX toxin-activating protein C; hypothetical protein YP_001609110.1 Hemolysin secretion protein D in E. coli,chromosomal (P09986) ,InterPro; Secretion protein HlyD; hypothetical protein YP_001609114.1 conserved hypothetical integral membrane protein with predicted signal peptide; hypothetical protein YP_001609115.1 homologous to predicted integral membrane protein [Mesorhizobium sp. BNC1]; hypothetical protein YP_001609119.1 DNA-binding response regulator,InterPro; Response regulator receiver; hypothetical protein YP_001609122.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001609123.1 cytochrome c-type biogenesis protein (cycK) (ccmF),InterPro; Cytochrome c assembly protein; hypothetical protein YP_001609124.1 cytochrome c-type biogenesis protein (cycL)(ccmH),InterPro; Cytochrome C biogenesis protein; hypothetical protein YP_001609126.1 homologous to transcriptional regulatory protein CusR of E. coli (P77380) ,InterPro; Response regulator receiver; hypothetical protein YP_001609127.1 InterPro; Histidine kinase; hypothetical protein YP_001609128.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001609129.1 homologous to hemin binding protein d [Bartonella henselae str. Houston-1];,homologous to 31 kDa outer-membrane immunogenic protein precursor of Brucella melitensis (P0A3U4); hypothetical protein YP_001609130.1 putative integrase, only weak similarity; hypothetical protein YP_001609131.1 InterPro; Metallo-phosphoesterase; hypothetical protein YP_001609135.1 putative regulator;,homologous to MOXR PROTEIN [Brucella melitensis 16M]; hypothetical protein YP_001609136.1 InterPro; Polynucleotide adenylyltransferase; hypothetical protein YP_001609138.1 InterPro; Ubiquinol-cytochrome c reductase iron-sulfur subunit; hypothetical protein YP_001609139.1 InterPro; Cytochrome b/b6 N-terminal; hypothetical protein YP_001609140.1 InterPro; Cytochrome c1; hypothetical protein YP_001609142.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001609144.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001609145.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001609147.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001609148.1 InterPro; Protein of unknown function DUF152; hypothetical protein YP_001609149.1 homologous to ATP synthase beta subunit/transription termination factor rho [Brucella melitensis 16M],InterPro; Protein of unknown function DUF185; hypothetical protein YP_001609150.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001609151.1 InterPro; Protein of unknown function DUF526; hypothetical protein YP_001609153.1 homologous to OSMOLARITY SENSOR PROTEIN ENVZ [Brucella melitensis 16M] (P02933 in E. coli),InterPro; Histidine kinase; hypothetical protein YP_001609154.1 InterPro; Response regulator receiver; hypothetical protein YP_001609155.1 homologous to hypothetical protein ycbL of E. coli (P75849);,homologous to hydroxyacylglutathione hydrolase of Brucella melitensis,InterPro; Beta-lactamase-like; hypothetical protein YP_001609156.1 hypothetical protein with predicted signal peptide and transmembrane helices,InterPro; Cytochrome c oxidase subunit III; hypothetical protein YP_001609157.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001609159.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001609160.1 InterPro; Glycosyl transferase group 1; hypothetical protein YP_001609161.1 Trk system potassium uptake protein TrkH (P21166 in E. coli),InterPro; Cation transporter; hypothetical protein YP_001609162.1 thioredoxin reductase (EC 1.8.1.9); P09625 in E. coli YP_001609163.1 similar to putative HTH-type transcriptional regulator yafC of E. coli (P30864),InterPro; LysR substrate binding domain; hypothetical protein YP_001609164.1 integrase signature; hypothetical protein YP_001609165.1 weak integrase signature; hypothetical protein YP_001609166.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001609167.1 Cold shock protein CspA/CspG (CPS-G),InterPro; Cold-shock DNA-binding domain; hypothetical protein YP_001609168.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001609169.1 partial homology to bifunctional regulatory protein/DNA repair protein [Yersinia pseudotuberculosis IP 32953],InterPro; Methylated-DNA-[protein]-cysteine S-methyltransferase; hypothetical protein YP_001609170.1 InterPro; Histidine kinase; hypothetical protein YP_001609171.1 aminopeptidase N (EC 3.4.11.2); alpha-aminoacylpeptide hydrolase; membrane alanine aminopeptidase; peptidase M1 membrane alanine aminopeptidase YP_001609174.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_001609175.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001609176.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_001609178.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001609179.1 prophage protein; hypothetical protein YP_001609180.1 with HmuTU is involved in the transport of hemin YP_001609181.1 permease of ABC transporterInterPro: FecCD transport family; hypothetical protein YP_001609182.1 ABC-type hemin transport system, periplasmic component,InterPro; Periplasmic binding protein; hypothetical protein YP_001609183.1 putative heme-degradation protein of a hemin ABC transporter system,InterPro; Haemin-degrading; hypothetical protein YP_001609184.1 Hemoglobin-haptoglobin utilization protein B precursor; a receptor for hemoglobin or the hemoglobin/haptoglobin complex and is required for heme uptake (ABC transporter); heme receptor,InterPro; TonB-dependent receptor protein; hypothetical protein YP_001609185.1 periplasmic protein TonB, links inner and outer membranes; energy transducer; hypothetical protein YP_001609187.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001609188.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001609189.1 putative uracil-DNA glycosylase (ung),InterPro; Uracil-DNA glycosylase superfamily; hypothetical protein YP_001609190.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001609192.1 orotate phosphoribosyltransferase 2 (EC 2.4.2.10); orotate phosphoribosyltransferase thermus type; involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001609194.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001609195.1 signal peptidase I (EC 3.4.21.89); leader peptidase I YP_001609196.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001609197.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001609198.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001609199.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001609200.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001609201.1 Predicted hydrolases of HD superfamily; hypothetical protein YP_001609203.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001609204.1 integrase fragment; hypothetical protein YP_001609206.1 cysteinyl-tRNA synthetase (EC 6.1.1.16); cysteine-tRNA ligase; cysteinyl-tRNA synthetase class Ia; catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001609207.1 conserved hypothetical membrane-spanning protein,InterPro; Protein of unknown function DUF421; hypothetical protein YP_001609208.1 ABC transporter ATP-binding/permease; homologous to heavy metal tolerance protein precursor [Brucella melitensis 16M],InterPro; ABC transporter transmembrane region; hypothetical protein YP_001609209.1 phosphatidylserine decarboxylase proenzyme (EC 4.1.1.65); contains: Phosphatidylserine decarboxylase alpha chain; phosphatidylserine decarboxylase beta chain; catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_001609210.1 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8); phosphatidylserine synthase; CDP-alcohol phosphatidyltransferase YP_001609212.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001609213.1 Colicin V production protein (dedE protein) (Pur regulon 18 kDa protein),InterPro; Colicin V production protein; hypothetical protein YP_001609214.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001609215.1 unwinds double stranded DNA YP_001609216.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001609217.1 predicted membrane protein with signal peptide; hypothetical protein YP_001609218.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001609219.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001609220.1 predicted membrane protein; similar to putative permease [Escherichia coli K12],InterPro; PA-phosphatase related phosphoesterase; hypothetical protein YP_001609222.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001609223.1 carries the fatty acid chain in fatty acid biosynthesis YP_001609224.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001609225.1 similarity to predicted periplasmic solute-binding proteins,InterPro; Protein of unknown function DUF175; hypothetical protein YP_001609226.1 guanylate kinase (EC 2.7.4.8); guanylate kinase/L-type calcium channel region; Essential for recycling GMP and indirectly, cGMP YP_001609227.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001609228.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001609230.1 Organic solvent tolerance protein precursor,InterPro; Organic solvent tolerance protein; hypothetical protein YP_001609231.1 predicted permease,InterPro; Predicted permease YjgP/YjgQ family; hypothetical protein YP_001609232.1 hypothetical membrane spanning protein with predicted signal peptide InterPro; Predicted permease YjgP/YjgQ family; hypothetical protein YP_001609233.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001609235.1 ABC transporter; similarity to Proline/betaine transporter of E.coli (Proline porter II) (PPII),InterPro; Major facilitator superfamily; hypothetical protein YP_001609236.1 InterPro; Outer membrane autotransporter barrel; hypothetical protein YP_001609237.1 InterPro; Outer membrane autotransporter barrel; hypothetical protein YP_001609238.1 InterPro; Outer membrane autotransporter barrel; hypothetical protein YP_001609239.1 nucleoside diphosphate kinase (EC 2.7.4.6); nucleoside-2-P kinase; catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001609241.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001609242.1 similar to putative cytoplasmic protein of Salmonella typhimurium LT2: STM3596,InterPro; Protein of unknown function DUF519; hypothetical protein YP_001609243.1 Sec-independent protein translocase tatA/E ,InterPro; Bacterial sec-independent translocation protein mttA/Hcf106; hypothetical protein YP_001609245.1 Sec-independent protein translocase tatC,InterPro; Sec-independent periplasmic protein translocase; hypothetical protein YP_001609246.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001609247.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001609248.1 homologous to nlpD antigen (virulence determinant) (lipoprotein) BQ04790 in Bartonella quintana, BH05630 in Bartonella henselae;,homologous to 43 kDa antigen [Bartonella bacilliformis];,homologous to peptidase,M23/M37 family [Brucella abortus biovar 1 str. 9-941] ,InterPro: Peptidase M23/M37; hypothetical protein YP_001609249.1 Immunogenic membrane protein; translocase yajC,InterPro; YajC; hypothetical protein YP_001609250.1 homologous to hypothetical outer membrane proteins,InterPro; Protein of unknown function DUF598; hypothetical protein YP_001609253.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001609254.1 Protein-export membrane protein (Preprotein translocase SecG subunit),InterPro; Preprotein translocase SecG subunit; hypothetical protein YP_001609255.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001609256.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001609257.1 enolase (EC 4.2.1.11); 2-phosphoglycerate dehydratase; 2-phospho-D-glycerate hydro-lyase; bacterial transferase hexapeptide repeat; enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001609258.1 predicted membrane protein,InterPro; TM2; hypothetical protein YP_001609259.1 predicted membrane protein,InterPro; TM2; hypothetical protein YP_001609260.1 predicted membrane protein,InterPro; TM2; hypothetical protein YP_001609261.1 similar to septum formation initiators,InterPro; Septum formation initiator; hypothetical protein YP_001609263.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase YP_001609265.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001609266.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001609267.1 homologous to Oligoketide cyclase/lipid transport protein [Mesorhizobium sp. BNC1],InterPro: Protein of unknown function UPF0083; hypothetical protein YP_001609268.1 InterPro; CinA C-terminal; hypothetical protein YP_001609269.1 Region start changed from 927188 to 927308 (120 bases) YP_001609270.1 rhizobial iron regulator; in Sinorhizobium meliloti mutations in this gene affect the expression of a number of iron-responsive operons YP_001609271.1 homologous to nitrogen regulation protein NtrY [Brucella abortus biovar 1 str. 9-941] ,InterPro; Histidine kinase; hypothetical protein YP_001609272.1 homologous to NITROGEN ASSIMILATION REGULATORY PROTEIN NTRX [Brucella melitensis 16M],InterPro: Response regulator NtrC type; hypothetical protein YP_001609273.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001609275.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001609276.1 binds and unfolds substrates as part of the ClpXP protease YP_001609279.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_001609280.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001609281.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001609282.1 Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis YP_001609284.1 putative membrane protein with 6 predicted TMH;,homologous to INTEGRAL MEMBRANE PROTEIN (Rhomboid family) [Brucella melitensis 16M],InterPro; Rhomboid-like protein; hypothetical protein YP_001609285.1 InterPro; Protein of unknown function DUF175; hypothetical protein YP_001609286.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001609287.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001609288.1 Modulates Rho-dependent transcription termination YP_001609289.1 binds directly to 23S ribosomal RNA YP_001609290.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001609291.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001609292.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001609293.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001609294.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001609295.1 putative transcriptional regulator;,partial similarity to HTH-type transcriptional regulator cueR (Copper efflux regulator) (Copper export regulator) of Vibrio cholerae (Q9KTC8),InterPro; Bacterial regulatory protein MerR family; hypothetical protein YP_001609296.1 InterPro; Nitroreductase family; hypothetical protein YP_001609300.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001609301.1 ATP-dependent Clp protease; ATP-binding subunit ClpA,InterPro; AAA ATPase central region; hypothetical protein YP_001609302.1 InterPro; Histidine triad (HIT) protein; hypothetical protein YP_001609303.1 putative translation initiation inhibitor,InterPro; Endoribonuclease L-PSP; hypothetical protein YP_001609304.1 Region start changed from 974400 to 974439 (-39 bases) YP_001609305.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001609306.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001609307.1 Catalyzes the phosphorylation of UMP to UDP YP_001609308.1 rrf; Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001609311.1 InterPro; Bacterial surface antigen (D15); hypothetical protein YP_001609312.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001609313.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001609314.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001609316.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001609319.1 homologous to amino acid ABC transporter in Pseudomonas putida:,permease PP3594 - Pseudomonas putida (strain KT2440) NP_745730.1;,InterPro; Binding-protein-dependent transport systems inner membrane component; hypothetical protein YP_001609320.1 homologous to amino acid ABC transporter in Pseudomonas putida:,periplasmic amino acid-binding protein PP3593 - Pseudomonas putida (strain KT2440) NP_745729.1,InterPro; Bacterial extracellular solute-binding protein family 3; hypothetical protein YP_001609321.1 homologous to amino acid ABC transporter in Pseudomonas putida:,periplasmic amino acid-binding protein PP3593 - Pseudomonas putida (strain KT2440) NP_745729.1,InterPro; Bacterial extracellular solute-binding protein family 3; hypothetical protein YP_001609322.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001609323.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001609324.1 homologous to DNA uptake protein [Mesorhizobium loti MAFF303099],InterPro; ComEC/Rec2-related protein; hypothetical protein YP_001609325.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001609327.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001609329.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001609330.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001609332.1 catalyzes the phosphorylation of NAD to NADP YP_001609333.1 Hypothetical protein yjiJ (P39381 in E. coli);,homologous to putative sugar transport protein [Escherichia coli K12]; hypothetical protein YP_001609336.1 putative phage-tail protein; hypothetical protein YP_001609337.1 homologous to late control gene D protein (GpD) of Bacteriophage 186 (P21679); hypothetical protein YP_001609338.1 homologous to lipoprotein, putative [Brucella suis 1330],InterPro; Orotate phosphoribosyltransferase Thermus type; hypothetical protein YP_001609343.1 homologous to killer protein VapD [Bartonella henselae str. Houston-1];,homologous to proteic killer protein, putative [Pseudomonas syringae pv. tomato str. DC3000] ,InterPro; Plasmid maintenance system killer; hypothetical protein YP_001609346.1 phage anti-repressor protein;,partially similar to hypothetical protein HI1422 of Haemophilus influenzae (P44193); hypothetical protein YP_001609349.1 homologous to DNA-binding protein BH03510 [Bartonella henselae str. Houston-1],InterPro; Protein of unknown function UPF0150; hypothetical protein YP_001609352.1 Single-strand binding protein (SSB) (Helix-destabilizing protein) (Q8YHC2 in Brucella melitensis),InterPro; Single-strand binding protein; hypothetical protein YP_001609353.1 similar to putative HTH-type transcriptional regulator ydcQ of E. coli (P67697),InterPro; Protein of unknown function UPF0150; hypothetical protein YP_001609356.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1] and to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609357.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1] and to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609359.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609361.1 homologous to BH03630; hypothetical protein YP_001609362.1 homologous to BH03640; hypothetical protein YP_001609363.1 InterPro: Helix-turn-helix motif; hypothetical protein YP_001609364.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609369.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609370.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609371.1 similar to Orf52 [Pseudomonas phage D3],InterPro; ERF; hypothetical protein YP_001609373.1 homologous to phage related protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609374.1 phage-related integrase,InterPro; Phage integrase; hypothetical protein YP_001609377.1 partly homologous to recombination protein bet of bacteriophage Lambda (P03698),InterPro; RecT protein; hypothetical protein YP_001609378.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609379.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609381.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609382.1 partly homologous to hypothetical genomic island protein BH06940 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609383.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609384.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609386.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1] and to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609387.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1] and to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609388.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609390.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609391.1 Single-strand binding protein (SSB) (Helix-destabilizing protein) (Q8YHC2 in Brucella melitensis),InterPro; Single-strand binding protein; hypothetical protein YP_001609392.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609393.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609394.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609395.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat,InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609396.1 InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001609401.1 homologous to hypothetical genomic island protein BH09010 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609402.1 hypothetical prophage integrase,InterPro; Phage integrase; hypothetical protein YP_001609404.1 hypothetical protein with predicted signal peptide; hypothetical protein YP_001609405.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609406.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609407.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609408.1 homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19];,weak similarity to hypothetical protein ydcK of E. coli (P76100),InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609409.1 InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001609410.1 similar to hypothetical membrane spanning protein [Brucella melitensis 16M];,weak similarity to hypothetical protein yfjI of E.coli (P52124); hypothetical protein YP_001609412.1 hypothetical prophage integrase,InterPro; Phage integrase; hypothetical protein YP_001609414.1 Terminase large subunit (G2P); hypothetical protein YP_001609415.1 partly similar to portal protein (Protein gp1) of bacteriophage P22 (P26744); hypothetical protein YP_001609416.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609417.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609418.1 homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19];,weak similarity to hypothetical protein ydcK of E. coli (P76100),InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609419.1 InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001609420.1 Hemolysin activator protein precursor; similar to hemolysin activator protein, HlyB family (Pseudomonas syringae pv. tomato str. DC3000),NP_793015.1, 28870396, InterPro; Hemolysin activator HlyB; hypothetical protein YP_001609427.1 hypothetical prophage integrase,InterPro; Phage integrase; hypothetical protein YP_001609429.1 hypothetical prophage integrase,InterPro; Phage integrase; hypothetical protein YP_001609431.1 similar to hypothetical membrane spanning protein [Brucella melitensis 16M];,weak similarity to hypothetical protein yfjI of E.coli (P52124); hypothetical protein YP_001609432.1 InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001609433.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609434.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Protein of unknown function DUF421; hypothetical protein YP_001609435.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609436.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609437.1 hypothetical protein with predicted signal peptide; hypothetical protein YP_001609438.1 partially homologous to expressed protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609439.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609440.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609441.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609442.1 InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001609443.1 similar to hypothetical membrane spanning protein [Brucella melitensis 16M]; hypothetical protein YP_001609444.1 homologous to yacB [Plasmid ColIb-P9],InterPro; Plasmid stabilization system; hypothetical protein YP_001609445.1 homologous to putative yacA [Plasmid ColIb-P9]; hypothetical protein YP_001609446.1 InterPro; Phosphatidate cytidylyltransferase; hypothetical protein YP_001609448.1 weakly similar to CP4-like integrase; hypothetical protein YP_001609449.1 hypothetical prophage integrase; hypothetical protein YP_001609452.1 homologous to COG2026: Cytotoxic translational repressor of toxin-antitoxin stability system [Psychrobacter sp. 273-4]; hypothetical protein YP_001609454.1 putative mebrane protein with predicted TMH (ten) and signal peptide;,weakly similar to hypothetical transport protein yyaM of Bacillus subtilis (P37511),InterPro; Protein of unknown function DUF6; hypothetical protein YP_001609455.1 InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001609456.1 similar to hypothetical membrane spanning protein [Brucella melitensis 16M];,weak similarity to hypothetical protein yfjI of E.coli (P52124); hypothetical protein YP_001609458.1 hypothetical prophage integrase,InterPro; Phage integrase; hypothetical protein YP_001609459.1 partially similar to expressed protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609460.1 homologous to hypothetical genomic island protein BH09350 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609461.1 homologous to hypothetical genomic island protein BH09350 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609463.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1];,homologous to hypothetical protein HI1419 of Haemophilus influenzae (P44190); hypothetical protein YP_001609467.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609468.1 partially similar to hypothetical genomic island protein BH09300 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609469.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609471.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609472.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609473.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609474.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro; Bacterial transferase hexapeptide repeat; hypothetical protein YP_001609475.1 InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001609476.1 partially similar to Hypothetical Membrane Spanning Protein [Brucella melitensis 16M]; hypothetical protein YP_001609480.1 hypothetical prophage integrase,InterPro; Phage integrase; hypothetical protein YP_001609482.1 phage related; hypothetical protein YP_001609485.1 weakly similar to COG5295: Autotransporter adhesin [Haemophilus somnus 129PT];,weakly similar to Laminin gamma-2 chain precursor (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit) (Q13753 in Human) ,InterPro; Bacterial chemotaxis sensory transducer; hypothetical protein YP_001609489.1 weak similarity to predicted transcriptional regulator [Psychrobacter sp. 273-4] and to predicted transcriptional regulator[Haemophilus somnus 2336]; hypothetical protein YP_001609490.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001609491.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001609493.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001609495.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001609497.1 homologous to Uracil-DNA glycosylase [Silicibacter sp. TM1040]; hypothetical protein YP_001609499.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001609500.1 major facilitator superfamily (MFS) transportersimilarity to MFS-type transporter protein ycaD of Escherichia coli (P21503),InterPro; Major facilitator superfamily; hypothetical protein YP_001609502.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001609504.1 putative integral membrane protein,InterPro; Protein of unknown function DUF205; hypothetical protein YP_001609505.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001609506.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001609509.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001609510.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001609511.1 ATP-binding protein LivF of High-affinity branched-chain amino acid transport system,InterPro: ABC transporter; hypothetical protein YP_001609512.1 ATP-binding protein livG of high-affinity branched-chain amino acid transport system (LIV-I protein G),InterPro: ABC transporter; hypothetical protein YP_001609513.1 permease (LivM) of high-affinity branched-chain amino acid transport system ,InterPro; Bacterial inner-membrane translocator; hypothetical protein YP_001609514.1 permease LivH of branched chain amino acid ABC transporter(LIV-I protein H),InterPro; Bacterial inner-membrane translocator; hypothetical protein YP_001609515.1 ABC-type branched-chain amino acid transport systems, periplasmic aa-binding protein,homologous to Leucine- isoleucine- valine- threonine- and alanine-binding protein precursor (LIVAT-BP) of Pseudomonas aeruginosa (Leu/Ile/Val/Thr/Ala-binding protein),InterPro; Extracellular ligand-binding receptor,branched-chain amino acid transport system; hypothetical protein YP_001609516.1 (Q9S170) Cold shock-like protein cspG,InterPro; Cold-shock DNA-binding domain; hypothetical protein YP_001609521.1 Q9ZCD3; methionine aminopeptidase (EC 3.4.11.18); peptidase M; methionine aminopeptidase subfamily 1; catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001609522.1 Regulatory factor involved in maltose metabolism YP_001609524.1 glutamate racemase (EC 5.1.1.3); Asp/Glu racemase; converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001609525.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001609526.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001609527.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_001609528.1 Represses a number of genes involved in the response to DNA damage YP_001609529.1 (Q9ZDE1) RlpA-like protein,InterPro; Rare lipoprotein A; hypothetical protein YP_001609531.1 thymidylate kinase (EC 2.7.4.9); catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001609532.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001609533.1 methionyl-tRNA synthetase (EC 6.1.1.10); methionine--tRNA ligase; methionyl-tRNA synthetase class Ia; methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001609537.1 Hypothetical Membrane Spanning Protein; hypothetical protein YP_001609538.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA YP_001609539.1 Region start changed from 1247685 to 1247649 (-36 bases) YP_001609540.1 outative 2-octaprenyl-6-methoxyphenol 4-monoxygenase,InterPro; Flavoprotein monooxygenase; hypothetical protein YP_001609544.1 InterPro; Protein of unknown function DUF511; hypothetical protein YP_001609547.1 homologous to phenylacetic acid degradation protein paaD of E. coli (part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation) (P76080),InterPro; Protein of unknown function DUF59; hypothetical protein YP_001609550.1 (P77499) Probable ATP-dependent transporter sufC,ABC-type transport system involved in Fe-S cluster assembly, ATPase component,InterPro: ABC transporter; hypothetical protein YP_001609551.1 with SufCD activates cysteine desulfurase SufS YP_001609553.1 Predicted hydrolase of the alpha/beta superfamily,InterPro; Esterase/lipase/thioesterase; hypothetical protein YP_001609554.1 tyrosyl-tRNA synthetase (EC 6.1.1.1); tyrosine--tRNA ligase; tyrosyl-tRNA synthetase class Ib; catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001609556.1 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA YP_001609560.1 similar to Invasion protein B, involved in pathogenesis; hypothetical protein YP_001609562.1 (O05955) Transcription-repair coupling factor (TRCF),InterPro; Transcription-repair coupling factor; hypothetical protein YP_001609563.1 InterPro; Protein of unknown function DUF339; hypothetical protein YP_001609564.1 (Q8YGM0) Lipoprotein releasing system ATP-binding protein lolD,InterPro: ABC transporter; hypothetical protein YP_001609565.1 (Q87EF5) Lipoprotein releasing system transmembrane protein lolC,InterPro; Protein of unknown function DUF214; hypothetical protein YP_001609566.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001609567.1 putative metallo-beta-lactamase family protein,InterPro; Beta-lactamase-like; hypothetical protein YP_001609569.1 Catalyzes the transfer of electrons from NADH to quinone YP_001609570.1 Catalyzes the transfer of electrons from NADH to quinone YP_001609571.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001609572.1 Catalyzes the transfer of electrons from NADH to quinone YP_001609573.1 Catalyzes the transfer of electrons from NADH to quinone YP_001609574.1 Catalyzes the transfer of electrons from NADH to quinone YP_001609575.1 Catalyzes the transfer of electrons from NADH to quinone YP_001609576.1 Catalyzes the transfer of electrons from NADH to quinone YP_001609577.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001609578.1 Catalyzes the transfer of electrons from NADH to quinone YP_001609579.1 Catalyzes the transfer of electrons from NADH to quinone YP_001609580.1 Catalyzes the transfer of electrons from NADH to quinone YP_001609581.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001609582.1 Catalyzes the transfer of electrons from NADH to quinone YP_001609583.1 similar to Dam modification methylase [Bacteriophage B3],InterPro; N6 adenine-specific DNA methyltransferase D12 class; hypothetical protein YP_001609584.1 homologous to late control gene D protein (GpD) of Bacteriophage 186 (P21679); hypothetical protein YP_001609585.1 putative phage-tail protein; hypothetical protein YP_001609587.1 phage tail tape meausure protein, TP901 family; hypothetical protein YP_001609589.1 partly similar to hypothetical genomic island protein BH07900 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609590.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1];,weak similarity to major tail tube protein FII [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609591.1 major tail sheath protein FI,homologous to major tail sheath protein (Protein FI) of Bacteriophage P2 (P22501),InterPro; Phage tail sheath protein; hypothetical protein YP_001609596.1 phage protein gp26; baseplate assembly protein J (GpJ),InterPro; Baseplate J-like protein; hypothetical protein YP_001609597.1 weak homology to phage protein gp25 [Bartonella henselae str. Houston-1]; baseplate assembly protein W (GpW); hypothetical protein YP_001609601.1 similar to Mu-like prophage FluMu protein gp36 (P44230),InterPro; Phage virion morphogenesis (putative tail completion) protein; hypothetical protein YP_001609602.1 (P44230) Mu-like prophage FluMu protein gp36; hypothetical protein YP_001609603.1 similar to capsid protein [Bacteriophage B3]; hypothetical protein YP_001609604.1 weak similarity to hypothetical protein B3ORF37 [Bacteriophage B3]; hypothetical protein YP_001609605.1 similar to prophage MuSo2, protein Gp32, putative [Shewanella oneidensis MR-1]; hypothetical protein YP_001609606.1 similar to hypothetical protein [Escherichia coli O157:H7];,similar to F protein (gpF) (Protein gp30) of bacteriophage Mu (Q01259),InterPro; Phage putative head morphogenesis protein SPP1 gp7; hypothetical protein YP_001609607.1 Mu-like prophage FluMu protein gp29; hypothetical protein YP_001609608.1 Mu-like prophage FluMu protein gp28; hypothetical protein YP_001609609.1 Mu-like prophage FluMu protein gp27; hypothetical protein YP_001609610.1 weak similarity to hypothetical protein gp26 of Bacteriophage Mu; hypothetical protein YP_001609611.1 phage-related hypothetical protein; hypothetical protein YP_001609614.1 similar to Putative peptidoglycan binding domain 1 [Nitrosomonas europaea ATCC 19718]; hypothetical protein YP_001609616.1 similar to Mu-like prophage FluMu protein gp16 (P71387); hypothetical protein YP_001609617.1 similar to gp05 [Burkholderia cenocepacia phage BcepMu]; hypothetical protein YP_001609619.1 similar to BH01430 and to BQ01360; hypothetical protein YP_001609620.1 (P96343) Mu-like prophage FluMu DNA transposition protein B; hypothetical protein YP_001609621.1 (P07636) Transposase,(O05069) Mu-like prophage FluMu transposase A ,InterPro; Bacteriophage Mu transposase; hypothetical protein YP_001609624.1 similar to Chromosomal replication initiator protein dnaA,hypothetical genomic island protein; hypothetical protein YP_001609625.1 similar to Mu-like prophage FluMu DNA-binding protein Ner (P46496); hypothetical protein YP_001609626.1 hypothetical genomic island protein; hypothetical protein YP_001609627.1 similar to hypothetical genomic island protein BH09180 [Bartonella henselae str. Houston-1],InterPro; Protein of unknown function DUF477; hypothetical protein YP_001609628.1 similar to Dam modification methylase [Bacteriophage B3],InterPro; N6 adenine-specific DNA methyltransferase D12 class; hypothetical protein YP_001609629.1 (P21679) Late control gene D protein (GpD),putative regulator of late gene expression,Phage protein D; hypothetical protein YP_001609630.1 putative phage-tail protein; hypothetical protein YP_001609631.1 Phage protein U; hypothetical protein YP_001609632.1 (P51731) Hypothetical 72.8 kDa protein in lys 3region (ORF27),similar to phage tail tape meausure protein, TP901 family, putative [Wolbachia endosymbiont of Drosophila ananassae]; hypothetical protein YP_001609634.1 partly similar to hypothetical genomic island protein BH07900 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609635.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1];,weak similarity to major tail tube protein FII [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609636.1 major tail sheath protein FI,homologous to major tail sheath protein (Protein FI) of Bacteriophage P2 (P22501),InterPro; Phage tail sheath protein; hypothetical protein YP_001609641.1 phage protein gp26; baseplate assembly protein J (GpJ),InterPro; Baseplate J-like protein; hypothetical protein YP_001609642.1 weak homology to phage protein gp25 [Bartonella henselae str. Houston-1]; baseplate assembly protein W (GpW); hypothetical protein YP_001609646.1 similar to Mu-like prophage FluMu protein gp36 (P44230),InterPro; Phage virion morphogenesis (putative tail completion) protein; hypothetical protein YP_001609647.1 (P44230) Mu-like prophage FluMu protein gp36,InterPro; Cobalt transport protein; hypothetical protein YP_001609648.1 capsid protein [Bacteriophage B3]; hypothetical protein YP_001609649.1 weak similarity to hypothetical protein B3ORF37 [Bacteriophage B3]; hypothetical protein YP_001609650.1 similar to prophage MuSo2, protein Gp32, putative [Shewanella oneidensis MR-1]; hypothetical protein YP_001609651.1 similar to hypothetical protein [Escherichia coli O157:H7];,similar to F protein (gpF) (Protein gp30) of bacteriophage Mu (Q01259); hypothetical protein YP_001609654.1 similar to Orf7 [Photorhabdus luminescens]; hypothetical protein YP_001609655.1 Possible hemagglutinin DUF637,InterPro; Possible hemagglutinin DUF637; hypothetical protein YP_001609657.1 putative hemagglutinin-related protein; hypothetical protein YP_001609658.1 similar to Orf7 [Photorhabdus luminescens]; hypothetical protein YP_001609660.1 Hemolysin activator protein belonging to the hec family,InterPro; Hemolysin activator HlyB; hypothetical protein YP_001609661.1 C-terminal homology to other B. tribocorum helicase/methyltransferases; hypothetical protein YP_001609662.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001609663.1 NifU-related protein; hypothetical protein YP_001609664.1 InterPro; Protein of unknown function DUF37; hypothetical protein YP_001609665.1 threonyl-tRNA synthetase (EC 6.1.1.3); threonine--tRNA ligase; threonyl-tRNA synthetase class IIa; catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001609667.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001609668.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001609669.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001609670.1 similar to COG0458: Carbamoylphosphate synthase large subunit (split gene in MJ) [Mesorhizobium sp. BNC1]; hypothetical protein YP_001609672.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001609673.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001609674.1 riboflavin synthase alpha chain; catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001609676.1 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains,InterPro; Protein of unknown function DUF193; hypothetical protein YP_001609677.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001609678.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_001609679.1 Electron transfer protein 1 mitochondrial precursor,Uncharacterized protein required for cytochrome oxidase assembly,InterPro; Cytochrome oxidase assembly; hypothetical protein YP_001609680.1 similar to hypothetical protein BH07510 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609681.1 (P25519) GTP-binding protein hflX,InterPro; Small GTP-binding protein domain; hypothetical protein YP_001609682.1 Stimulates the elongation of poly(A) tails YP_001609683.1 similar to Kinesin-like protein [Brucella melitensis 16M]; hypothetical protein YP_001609684.1 NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate YP_001609685.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides YP_001609686.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001609687.1 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP. YP_001609689.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001609691.1 Uncharacterized conserved protein,HesB/YadR/YfhF family protein,InterPro; Protein of unknown function HesB/YadR/YfhF; hypothetical protein YP_001609692.1 (O86110) Small heat shock protein hspH,IbpA, 16 kDa heat shock protein A [Brucella abortus biovar 1 str. 9-941],InterPro; Heat shock protein Hsp20; hypothetical protein YP_001609693.1 Lysophospholipase l2 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609694.1 Response regulator,InterPro; Response regulator receiver; hypothetical protein YP_001609696.1 similar to ATPase involved in DNA replication initiation; hypothetical protein YP_001609697.1 Predicted permease,InterPro; Protein of unknown function UPF0118; hypothetical protein YP_001609698.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001609700.1 sensory box histidine kinase/response regulator,InterPro; Histidine kinase; hypothetical protein YP_001609705.1 adenylosuccinate lyase (EC 4.3.2.2); glutamyl-tRNA synthetase regulatory factor; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001609706.1 Predicted esterase of the alpha/beta hydrolase fold; hypothetical protein YP_001609707.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001609708.1 Phosphoribosylformylglycinamidine (FGAM) synthase,PurS component,InterPro; Protein of unknown function UPF0062; hypothetical protein YP_001609709.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001609710.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001609711.1 similar to bolA-related protein,InterPro; BolA-like protein; hypothetical protein YP_001609714.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001609715.1 aspartyl-tRNA synthetase (EC 6.1.1.12); aspartate--tRNA ligase; aspartyl-tRNA synthetase bacterial/mitochondrial type; catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001609716.1 ribonuclease D YP_001609717.1 InterPro; Ppx/GppA phosphatase; hypothetical protein YP_001609718.1 polyphosphate kinase 1 (EC 2.7.4.1); polyphosphoric acid kinase 1; ATP-polyphosphate phosphotransferase 1; catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001609719.1 Uncharacterized protein conserved in bacteria; hypothetical protein YP_001609720.1 catalyzes the formation of catechol from salicylate YP_001609721.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001609722.1 catalyzes branch migration in Holliday junction intermediates YP_001609723.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001609724.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001609725.1 (Q9KDL8) Cytochrome c-type biogenesis protein ccdA,InterPro; Cytochrome c biogenesis protein transmembrane region; hypothetical protein YP_001609727.1 HesB/YadR/YfhF family protein,InterPro; Protein of unknown function HesB/YadR/YfhF; hypothetical protein YP_001609728.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001609729.1 arginyl-tRNA synthetase (EC 6.1.1.19); arginine--tRNA ligase; arginyl-tRNA synthetase class Ic; catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001609730.1 similar to SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE [Brucella melitensis 16M]; hypothetical protein YP_001609732.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001609733.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001609734.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001609735.1 Converts isocitrate to alpha ketoglutarate YP_001609736.1 similar to major facilitator superfamily transporter homolog [Burkholderia pseudomallei K96243],InterPro; Major facilitator superfamily; hypothetical protein YP_001609737.1 similar to Dam modification methylase [Bacteriophage B3],InterPro; N6 adenine-specific DNA methyltransferase D12 class; hypothetical protein YP_001609738.1 homologous to late control gene D protein (GpD) of Bacteriophage 186 (P21679); hypothetical protein YP_001609739.1 putative phage-tail protein; hypothetical protein YP_001609741.1 (P51731) Hypothetical 72.8 kDa protein in lys 3region (ORF27),similar to phage tail tape meausure protein, TP901 family, putative [Wolbachia endosymbiont of Drosophila ananassae]; hypothetical protein YP_001609743.1 similar to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609744.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1];,weak similarity to major tail tube protein FII [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609745.1 major tail sheath protein FI,homologous to major tail sheath protein (Protein FI) of Bacteriophage P2 (P22501),InterPro; Phage tail sheath protein; hypothetical protein YP_001609750.1 phage protein gp26; baseplate assembly protein J (GpJ),InterPro; Baseplate J-like protein; hypothetical protein YP_001609751.1 weak homology to phage protein gp25 [Bartonella henselae str. Houston-1]; baseplate assembly protein W (GpW); hypothetical protein YP_001609755.1 similar to Mu-like prophage FluMu protein gp36 (P44230),InterPro; Phage virion morphogenesis (putative tail completion) protein; hypothetical protein YP_001609756.1 similar to Mu-like prophage FluMu protein gp36 (P44230); hypothetical protein YP_001609757.1 similar to capsid protein [Bacteriophage B3]; hypothetical protein YP_001609758.1 weak similarity to hypothetical protein B3ORF37 [Bacteriophage B3]; hypothetical protein YP_001609759.1 similar to prophage MuSo2, protein Gp32, putative [Shewanella oneidensis MR-1]; hypothetical protein YP_001609760.1 similar to hypothetical protein [Escherichia coli O157:H7];,similar to F protein (gpF) (Protein gp30) of bacteriophage Mu (Q01259),InterPro; Phage putative head morphogenesis protein SPP1 gp7; hypothetical protein YP_001609761.1 Mu-like prophage FluMu protein gp29; hypothetical protein YP_001609762.1 Mu-like prophage FluMu protein gp28; hypothetical protein YP_001609763.1 Mu-like prophage FluMu protein gp27; hypothetical protein YP_001609764.1 weak similarity to hypothetical protein gp26 of Bacteriophage Mu; hypothetical protein YP_001609768.1 similar to glycosidase [Bacteriophage 11b]; hypothetical protein YP_001609770.1 similar to Mu-like prophage FluMu protein gp16 (P71387); hypothetical protein YP_001609771.1 similar to gp05 [Burkholderia cenocepacia phage BcepMu]; hypothetical protein YP_001609774.1 Mu-like prophage FluMu DNA transposition protein B; hypothetical protein YP_001609775.1 Transposase; similar to Mu-like prophage FluMu transposase A of Haemophilus influenzae (O05069) ,InterPro; Bacteriophage Mu transposase; hypothetical protein YP_001609778.1 similar to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609779.1 Region start changed from 1519904 to 1519883 (-21 bases) YP_001609780.1 similar to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609781.1 homologous to hypothetical genomic island protein BH09180 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609782.1 (Q9GMU6) Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (QnpA-13170); hypothetical protein YP_001609783.1 (P58530) Probable sugar efflux transporterInterPro; General substrate transporter; hypothetical protein YP_001609784.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001609786.1 Integrase; hypothetical protein YP_001609789.1 phosphopantetheine adenylyltransferase (EC ~2.7.7.3); pantetheine-phosphate adenylyltransferase; dephospho-CoA pyrophosphorylase; coenzyme A biosynthesis protein; Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001609790.1 negatively supercoils closed circular double-stranded DNA YP_001609791.1 Single-strand binding protein (SSB) (Helix-destabilizing protein) (Q8YHC2 in Brucella melitensis),InterPro; Single-strand binding protein; hypothetical protein YP_001609792.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001609793.1 InterPro; Nitrogen regulatory protein P-II; hypothetical protein YP_001609796.1 homologous to putative chaperone [Mesorhizobium sp. BNC1]&&&ref|ZP_00196286.2| (REFSEQ); hypothetical protein YP_001609799.1 protein with 9 predicted TM helices and signal peptide,InterPro; Protein of unknown function DUF6; hypothetical protein YP_001609802.1 partial similarity to filamentous hemagglutinin; hypothetical protein YP_001609808.1 homolog of hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609810.1 Proline-specific permease proY (P37460 in Salmonella typhimurium) ,InterPro; Amino acid permease-associated region; hypothetical protein YP_001609812.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001609814.1 Hypothetical protein MJ1576 (Q58971 in Methanococcus jannaschii) ,InterPro; LemA family; hypothetical protein YP_001609815.1 partially similar to hypothetical protein ygcG of E. coli (P55140),InterPro; Protein of unknown function DUF477; hypothetical protein YP_001609816.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001609817.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001609819.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001609820.1 forms a direct contact with the tRNA during translation YP_001609827.1 homologous to daunorubicin resistance ATP-binding protein drrA [Bacillus cereus G9241];,InterPro: ABC transporter; hypothetical protein YP_001609828.1 InterPro; Pseudouridine synthase RluD; hypothetical protein YP_001609829.1 responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease component; Cgt; ChvA; NdvA YP_001609830.1 alanyl-tRNA synthetase (EC 6.1.1.7); alanine--tRNA ligase; alanyl-tRNA synthetase class IIc; Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001609831.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001609832.1 Hypothetical protein ycaJ (P45526 in E. coli) ,InterPro; AAA ATPase central region; hypothetical protein YP_001609834.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001609835.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001609836.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001609837.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001609838.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001609839.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001609840.1 late assembly protein YP_001609841.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001609842.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001609843.1 binds 5S rRNA along with protein L5 and L25 YP_001609844.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001609845.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001609846.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001609847.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001609848.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001609849.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001609850.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001609851.1 one of the stabilizing components for the large ribosomal subunit YP_001609852.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001609853.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001609854.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001609855.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001609856.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001609857.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001609858.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001609859.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001609860.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001609861.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001609862.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001609863.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001609864.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001609866.1 glutamate/aspartate periplasmic binding protein precursor gltI (Q9ZF60 in Salmonella typhimurium) ,InterPro; Bacterial extracellular solute-binding protein family 3; hypothetical protein YP_001609867.1 Glutamate/aspartate transport system permease gltJ (P41074 in E. coli) ,InterPro; Binding-protein-dependent transport systems inner membrane component; hypothetical protein YP_001609868.1 Glutamate/aspartate transport system permease gltK (P41075 in E. coli) ,InterPro; Binding-protein-dependent transport systems inner membrane component; hypothetical protein YP_001609869.1 Glutamate/aspartate transport ATP-binding protein gltL (P41076 in E. coli);,similar to glutamine transport ATP-binding protein glnQ (P27675 in Bacillus stearothermophilus) ,InterPro: ABC transporter; hypothetical protein YP_001609870.1 Exopolysaccharide production negative regulator precursor (Q52822 in Rhizobium leguminosarum (biovar viciae)),InterPro; Sel1-like repeat; hypothetical protein YP_001609871.1 valyl-tRNA synthetase; valyl-tRNA synthetase class Ia; valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001609877.1 threonine dehydratase biosynthetic (EC 4.3.1.19); threonine deaminase; pyridoxal-5-phosphate-dependent enzyme beta family; catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_001609878.1 similar to 31 kDa outer-membrane immunogenic protein precursor of Brucella melitensis (P0A3U4); hypothetical protein YP_001609879.1 hypothetical protein with predicted signal peptide; hypothetical protein YP_001609880.1 homologous to membrane protein [Brucella abortus biovar 1 str. 9-941],InterPro; Mechanosensitive (MS) ion channel; hypothetical protein YP_001609882.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001609883.1 homologous to POTASSIUM/PROTON ANTIPORTER ROSB [Brucella melitensis 16M];,homologous to hypothetical protein ybaL of E. coli (belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) (P39830),InterPro; Sodium/hydrogen exchanger; hypothetical protein YP_001609884.1 similar to hypothetical membrane protein slr0712 of Synechocystis sp. (Q55979);,homologous to LOW PH-INDUCED PROTEIN A [Brucella melitensis 16M];,weakly similar to hypothetical protein ybhN of E. coli (P75770); hypothetical protein YP_001609885.1 homologous to CBS domain protein [Brucella abortus biovar 1 str. 9-941] and to INTEGRAL MEMBRANE PROTEIN / HEMOLYSIN [Brucella melitensis 16M];,similar to hypothetical UPF0053 membrane protein yoaE (P76262),InterPro; Integral membrane protein TerC family; hypothetical protein YP_001609886.1 homologous to isomerase, putative [Neisseria meningitidis MC58] and to putative hydrolase [Neisseria meningitidis Z2491],InterPro; Fumarylacetoacetate (FAA) hydrolase; hypothetical protein YP_001609889.1 Ketol-acid reductoisomerase (EC 1.1.1.86); acetohydroxy-acid isomeroreductase; alpha-keto-beta-hydroxylacil reductoisomerase; acetohydroxy acid isomeroreductase; catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001609890.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001609891.1 homologous to exodeoxyribosylnuclease EdrN of Bradyrhizobium japonicum USDA 110; hypothetical protein YP_001609892.1 homologous to D-isomer specific 2-hydroxyacid dehydrogenase [Burkholderia pseudomallei K96243];,homologous to glyoxylate reductase [Burkholderia mallei ATCC 23344];,homologous to PUTATIVE D-3-PHOSPHOGLYCERATE DEHYDROGENASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum] ,InterPro; D-isomer specific 2-hydroxyacid dehydrogenase NAD binding domain; hypothetical protein YP_001609897.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001609901.1 dihydrofolate reductase type III (EC 1.5.1.3) YP_001609902.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001609903.1 Alpha-ketoglutarate permease of the major facilitator superfamily,InterPro; General substrate transporter; hypothetical protein YP_001609904.1 Alpha-ketoglutarate permease of the major facilitator superfamily,InterPro; General substrate transporter; hypothetical protein YP_001609905.1 Alpha-ketoglutarate permease of the major facilitator superfamily,InterPro; General substrate transporter; hypothetical protein YP_001609906.1 homolog of hypothetical protein BH11020 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609907.1 homolog of hypothetical protein BH11040 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609908.1 homolog of hypothetical protein BH11050 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609909.1 homolog to hypothetical protein BH11060 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609910.1 InterPro; UvrD/REP helicase; hypothetical protein YP_001609912.1 SCO1/SenC/PrrC, involved in biogenesis of respiratory systems,InterPro; Electron transport protein SCO1/SenC; hypothetical protein YP_001609913.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001609915.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001609917.1 predicted DNA uptake lipoprotein,InterPro; Protein of unknown function UPF0169; hypothetical protein YP_001609918.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001609919.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001609920.1 InterPro; Cell division protein FtsA; hypothetical protein YP_001609921.1 InterPro; Cell division protein FtsQ; hypothetical protein YP_001609922.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001609923.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001609924.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001609925.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001609926.1 Homolog of cell division protein ftsW [Bartonella henselae str. Houston-1],InterPro; Cell cycle protein; hypothetical protein YP_001609927.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001609928.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001609929.1 Homolog of UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- D-alanyl-D-alanine ligase [Bartonella henselae str. Houston-1],InterPro; moylalanyl-D-glutamyl-26-diaminopimelate-D-alanyl-D-alanyl ligase; hypothetical protein YP_001609930.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001609931.1 Cell division protein FtsI/penicillin-binding protein 2; homologous to Penicillin-binding protein 2 (PBP-2)of Neisseria gonorrhoeae (P08149),InterPro: Penicillin-binding protein transpeptidase domain; hypothetical protein YP_001609932.1 homolog of hypothetical protein BH11310 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609933.1 InterPro; Bacterial methyltransferase; hypothetical protein YP_001609934.1 Transmembrane protein [Bartonella henselae str. Houston-1], Similar to membrane-bound lytic murein transglycosylase E (Murein hydrolase E),InterPro: SLT domain; hypothetical protein YP_001609935.1 Homologous to hypothetical protein BH11360 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609937.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001609938.1 Homologous to hypothetical protein BH11390 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609939.1 Homologous to Pyrazinamidase /nicotinamidase pncA [Bartonella henselae str. Houston-1]; similar to Pyrazinamidase/nicotinamidase (PZAase) (Nicotine deamidase) (NAMase) (P21369),InterPro; Isochorismatase hydrolase family; hypothetical protein YP_001609940.1 Conserved hypothetical membrane protein with predicted TMH (ten);,homologous to hypothetical protein BH11410 [Bartonella henselae str. Houston-1] and to membrane protein,putative [Brucella suis 1330],InterPro; Protein of unknown function DUF475; hypothetical protein YP_001609941.1 Homologous to hypothetical protein BH11420 [Bartonella henselae str. Houston-1]; HTH-type transcriptional regulator xre (Putative pbsX repressor) (P23789),InterPro: Helix-turn-helix motif; hypothetical protein YP_001609943.1 Homologous to phage related protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609944.1 weakly similar to phage related protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609947.1 Homologous to hypothetical protein BH11520 [Bartonella henselae str. Houston-1], Bacterial protein of unknown function (DUF838);,homologous to hypothetical protein ycgN of E. coli (P0A8L5),InterPro; Uncharacterised conserved protein UCP006173; hypothetical protein YP_001609951.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001609952.1 synthesizes RNA primers at the replication forks YP_001609953.1 putative small-conductance mechanosensitive channel protein,InterPro; Mechanosensitive (MS) ion channel; hypothetical protein YP_001609954.1 Na/Pi-cotransporter family protein,InterPro; Na+/Pi-cotransporter; hypothetical protein YP_001609956.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_001609957.1 similar to hypothetical protein yqeY of Bacillus subtilis (P54464); hypothetical protein YP_001609958.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001609962.1 Homolog of hypothetical protein BH11610 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609963.1 Homolog of hypothetical protein BH12000 [Bartonella henselae str. Houston-1]; similar to cation efflux family protein [Brucella abortus biovar 1 str. 9-941]; COBALT-ZINC-CADMIUM RESISTANCE PROTEIN CZCD [Brucella melitensis 16M],InterPro; Cation efflux protein; hypothetical protein YP_001609964.1 Hypothetical tRNA/rRNA methyltransferase, SpoU rRNA Methylase family,InterPro; tRNA/rRNA methyltransferase (SpoU); hypothetical protein YP_001609965.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001609968.1 Cell cycle transcriptional regulator ctrA (Response regulator sokA) (Q45994 in Caulobacter crescentus) ,InterPro; Response regulator receiver; hypothetical protein YP_001609973.1 similar to pleiotropic regulatory protein degT of Bacillus stearothermophilus (P15263);,similar to WecE protein [Mannheimia succiniciproducens MBEL55E];,similar to hypothetical protein yfbE of E. coli (P77690),InterPro; DegT/DnrJ/EryC1/StrS aminotransferase; hypothetical protein YP_001609974.1 homologous to oxidoreductase, Gfo/Idh/MocA family [Brucella suis 1330],InterPro; Oxidoreductase N-terminal; hypothetical protein YP_001609977.1 homologous to late control gene D protein (GpD) of Bacteriophage 186 (P21679); hypothetical protein YP_001609978.1 putative phage-tail protein; hypothetical protein YP_001609980.1 hypothetical protein with predicted TMH (five),partial similarity to phage tail tape meausure protein, TP901 family, putative [Wolbachia endosymbiont of Drosophila ananassae]; hypothetical protein YP_001609981.1 Homologous to hypothetical genomic island protein BH09160 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609982.1 Homologous to hypothetical protein BH13160 [Bartonella henselae str. Houston-1],InterPro; Outer membrane autotransporter barrel; hypothetical protein YP_001609983.1 Homologous to probable surface protein BH13140 [Bartonella henselae str. Houston-1],InterPro; Outer membrane autotransporter barrel; hypothetical protein YP_001609984.1 Homologous to hypothetical protein BH13160 [Bartonella henselae str. Houston-1],InterPro; Outer membrane autotransporter barrel; hypothetical protein YP_001609985.1 Homologous to hypothetical protein BH13120 [Bartonella henselae str. Houston-1],InterPro; Outer membrane autotransporter barrel; hypothetical protein YP_001609986.1 Homologous to hypothetical protein BH13180 [Bartonella henselae str. Houston-1],InterPro; Outer membrane autotransporter barrel; hypothetical protein YP_001609990.1 Homologous to hypothetical protein BH13190 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001609991.1 Similar to hypothetical protein [Zymomonas mobilis]; hypothetical protein YP_001609992.1 ATPases involved in chromosome partitioning,InterPro: ATPase ParA type; hypothetical protein YP_001609993.1 Homologous to BH13210 [Bartonella henselae str. Houston-1],InterPro; Protein of unknown function DUF442; hypothetical protein YP_001609994.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001609995.1 Homolog of HAD superfamily protein involved in N-acetyl-glucosamine catabolism in Brucella melitensis 16M (&&&ref|NP_542023.1|),InterPro; HAD-superfamily subfamily IIA hydrolase hypothetical 3; hypothetical protein YP_001609997.1 Similar to Micrococcal nuclease (thermonuclease) homologs in Mesorhizobium sp. BNC1 (&&&ref|ZP_00196839.1|),InterPro; Staphylococcus nuclease (SNase-like); hypothetical protein YP_001609998.1 Component of type IV secretion system; hypothetical protein YP_001609999.1 Component of type IV secretion system,InterPro; Type IV secretory pathway VirB3-like; hypothetical protein YP_001610000.1 Component of type IV secretion system,InterPro; CagE TrbE VirB family component of type IV transporter system; hypothetical protein YP_001610001.1 17-kDa antigen precursor, component of type IV secretion system; hypothetical protein YP_001610002.1 Component of type IV secretion system,InterPro; TrbL/VirB6 plasmid conjugal transfer protein; hypothetical protein YP_001610003.1 15-kDa antigen protein precursor, component of type IV secretion system; hypothetical protein YP_001610004.1 Component of type IV secretion system,InterPro; VirB8; hypothetical protein YP_001610005.1 Component of type IV secretion system,InterPro; Type IV secretion system CagX conjugation protein; hypothetical protein YP_001610006.1 Component of type IV secretion system,InterPro; Bacterial conjugation TrbI-like protein; hypothetical protein YP_001610007.1 Component of type IV secretion system,InterPro; Bacterial type II secretion system protein E; hypothetical protein YP_001610008.1 Homologous to; hypothetical protein YP_001610009.1 homologous to BepA protein of Bartonella henselae (&&&ref|YP_034062.1|), putative protein substrate of type IV secretion system, putative cell filamentation protein; hypothetical protein YP_001610010.1 VirD4 family YP_001610011.1 Homologous to BepC protein of Bartonella henselae (&&&ref|YP_034065.1|), putative protein substrate of type IV secretion system,InterPro; Filamentation induced by cAMP protein Fic; hypothetical protein YP_001610012.1 Homologous to BepD protein of Bartonella henselae (&&&ref|YP_034066.1|), putative protein substrate of type IV secretion system; hypothetical protein YP_001610014.1 Homologous to BepE protein of Bartonella henselae (&&&ref|YP_034067.1|), putative protein substrate of type IV secretion system; hypothetical protein YP_001610015.1 Homologous to BepF protein of Bartonella henselae (&&&ref|YP_034068.1|), putative substrate for type IV secretion system,InterPro; Proline-rich region; hypothetical protein YP_001610016.1 Bep I protein, homologous to BepA protein (&&&ref|YP_034062.1|) and BepC protein (&&&ref|YP_034065.1|) of Bartonella henselae,putative protein substrate for type IV secretion system,InterPro; Filamentation induced by cAMP protein Fic; hypothetical protein YP_001610017.1 Virulence factor MviN homolog,InterPro; Virulence factor MVIN-like; hypothetical protein YP_001610018.1 tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase class Ib; catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001610019.1 Homolog of universal stress protein UspA and related nucleotide-binding proteins,InterPro; Usp domain; hypothetical protein YP_001610022.1 phosphoglucomutase (EC 5.4.2.2); glucose phosphomutase; ohosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001610024.1 partially similar to 20.9 kDa protein (ORF 2) of Zymomonas mobilis plasmid pZM2 (P15256);,partially similar to Rep protein [Bartonella grahamii]; hypothetical protein YP_001610025.1 histidyl-tRNA synthetase (6.1.1.21); histidyl-tRNA synthetase class IIa; catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001610027.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001610030.1 Similar to type III restriction system endonuclease [Burkholderia pseudomallei K96243]; similar to type III restriction-modification system EcoPI enzyme res (P08764) ,InterPro; Type III restriction enzyme res subunit; hypothetical protein YP_001610031.1 similar to zinc uptake regulation protein (Zinc uptake regulator) of E. coli (P32692) ,InterPro; Ferric-uptake regulator; hypothetical protein YP_001610032.1 Homolog of multidrug resistance protein vceA [Bartonella henselae str. Houston-1]; similar to multidrug resistance protein K (P52599),InterPro; Secretion protein HlyD; hypothetical protein YP_001610033.1 Homolog of multidrug resistance protein vceB [Bartonella henselae str. Houston-1]; similar to multidrug resistance protein B (P27304) ,InterPro; Major facilitator superfamily; hypothetical protein YP_001610036.1 InterPro; Rhodanese-like; hypothetical protein YP_001610040.1 alanine racemase 1 (EC 5.1.1.1); provides the D-alanine required for cell wall biosynthesis YP_001610041.1 putative integrase; hypothetical protein YP_001610042.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001610043.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001610044.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001610046.1 Protein ycaR (P75844 in E. coli) ,InterPro; Protein of unknown function DUF343; hypothetical protein YP_001610048.1 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11); aspartate-semialdehyde dehydrogenase USG-1 related; catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001610050.1 homologous to D-methionine-binding lipoprotein metQ precursor of Escherichia coli (P28635),InterPro; Lipoprotein YaeC; hypothetical protein YP_001610051.1 homologous to D-methionine transport ATP-binding protein metN of Escherichia coli (P30750),InterPro: ABC transporter; hypothetical protein YP_001610052.1 homologous to D-methionine transport system permease protein metI of Escherichia coli (P30750),InterPro; Binding-protein-dependent transport systems inner membrane component; hypothetical protein YP_001610053.1 integrase fragment; hypothetical protein YP_001610054.1 probable integrase fragment; hypothetical protein YP_001610055.1 integrase fragment; hypothetical protein YP_001610058.1 integrase fragment; hypothetical protein YP_001610060.1 InterPro; Creatininase; hypothetical protein YP_001610061.1 possible CobW protein involved in cobalamin synthesis,InterPro; Cobalamin synthesis protein/P47K; hypothetical protein YP_001610062.1 homologous to WD-repeat family proteins ,InterPro; G-protein beta WD-40 repeat; hypothetical protein YP_001610067.1 probable surface protein,InterPro; Filamentation induced by cAMP protein Fic; hypothetical protein YP_001610070.1 periplasmic binding protein precursor fatB/fecB/yclQ of an ABC-type iron-transport system,InterPro; Periplasmic binding protein; hypothetical protein YP_001610071.1 permease fatD/fecD/yclO of an ABC-type iron-transport system,InterPro: FecCD transport family; hypothetical protein YP_001610072.1 permease fatC/fecC/yclO of an ABC-type iron-transport system ,InterPro: FecCD transport family; hypothetical protein YP_001610073.1 ATPase component fecE/ceuD of an ABC-type iron-transport system (3.6.3.34),InterPro: ABC transporter; hypothetical protein YP_001610074.1 similar to Dam modification methylase [Bacteriophage B3],InterPro; N6 adenine-specific DNA methyltransferase D12 class; hypothetical protein YP_001610075.1 homologous to late control gene D protein (GpD) of Bacteriophage 186 (P21679); hypothetical protein YP_001610076.1 putative phage-tail protein; hypothetical protein YP_001610078.1 similar to prophage P2W3, tail tape measure protein [Wolbachia endosymbiont of Drosophila melanogaster]; hypothetical protein YP_001610080.1 partly similar to hypothetical genomic island protein BH07900 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610081.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1];,weak similarity to major tail tube protein FII [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610082.1 major tail sheath protein FI,homologous to major tail sheath protein (Protein FI) of Bacteriophage P2 (P22501),InterPro; Phage tail sheath protein; hypothetical protein YP_001610087.1 phage protein gp26; baseplate assembly protein J (GpJ),InterPro; Baseplate J-like protein; hypothetical protein YP_001610088.1 weak homology to phage protein gp25 [Bartonella henselae str. Houston-1]; baseplate assembly protein W (GpW); hypothetical protein YP_001610092.1 similar to Mu-like prophage FluMu protein gp36 (P44230),InterPro; Phage virion morphogenesis (putative tail completion) protein; hypothetical protein YP_001610093.1 similar to Mu-like prophage FluMu protein gp36 (P44230); hypothetical protein YP_001610094.1 similar to capsid protein [Bacteriophage B3]; hypothetical protein YP_001610095.1 weak similarity to hypothetical protein B3ORF37 [Bacteriophage B3]; hypothetical protein YP_001610096.1 similar to prophage MuSo2, protein Gp32, putative [Shewanella oneidensis MR-1]; hypothetical protein YP_001610097.1 similar to hypothetical protein [Escherichia coli O157:H7];,similar to F protein (gpF) (Protein gp30) of bacteriophage Mu (Q01259),InterPro; Phage putative head morphogenesis protein SPP1 gp7; hypothetical protein YP_001610098.1 Mu-like prophage FluMu protein gp29; hypothetical protein YP_001610099.1 Mu-like prophage FluMu protein gp28; hypothetical protein YP_001610100.1 Mu-like prophage FluMu protein gp27; hypothetical protein YP_001610101.1 weak similarity to hypothetical protein gp26 of Bacteriophage Mu; hypothetical protein YP_001610105.1 similar to glycosidase [Bacteriophage 11b]; hypothetical protein YP_001610107.1 similar to Mu-like prophage FluMu protein gp16 (P71387); hypothetical protein YP_001610108.1 similar to gp05 [Burkholderia cenocepacia phage BcepMu]; hypothetical protein YP_001610111.1 similar to Mu-like prophage FluMu DNA transposition protein B; hypothetical protein YP_001610112.1 Transposase; similar to Mu-like prophage FluMu transposase A of Haemophilus influenzae (O05069) ,InterPro; Bacteriophage Mu transposase; hypothetical protein YP_001610116.1 similar to Mu-like prophage FluMu DNA-binding protein Ner (P46496); hypothetical protein YP_001610117.1 InterPro: Helix-turn-helix motif; hypothetical protein YP_001610118.1 similar to Dam modification methylase [Bacteriophage B3],InterPro; N6 adenine-specific DNA methyltransferase D12 class; hypothetical protein YP_001610119.1 homologous to late control gene D protein (GpD) of Bacteriophage 186 (P21679); hypothetical protein YP_001610120.1 putative phage-tail protein; hypothetical protein YP_001610122.1 hypothetical protein with predicted TMH (three) and a signal peptide;,weak similarity to probable bacteriophage tail protein [Chromobacterium violaceum ATCC 12472]; hypothetical protein YP_001610123.1 hypothetical protein with predicted signal peptide,10 parallel beta-helix repeats, and an outer membrane autotransporter barrel (TIGR01414),InterPro; Outer membrane autotransporter barrel; hypothetical protein YP_001610131.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001610137.1 conserved in alpha-proteobacteria; homologous to BH12250; hypothetical protein YP_001610138.1 Homolog of hypothetical protein BH12260 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610139.1 Homolog of hypothetical protein BH12270 [Bartonella henselae str. Houston-1]; similar to hypothetical membrane protein [Brucella abortus biovar 1 str. 9-941],InterPro; Protein of unknown function DUF81; hypothetical protein YP_001610140.1 Homolog of hypothetical protein BH12280 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610146.1 homolog of hypothetical protein BH12340 [Bartonella henselae str. Houston-1] and of hypothetical protein BruAb1_0182 [Brucella abortus biovar 1 str. 9-941]; hypothetical protein YP_001610147.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001610148.1 InterPro; Bacterial regulatory protein, ArsR family (PF01022); hypothetical protein YP_001610149.1 homolog of MRP PROTEIN [Brucella melitensis 16M],InterPro; Protein of unknown function DUF59; hypothetical protein YP_001610150.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001610151.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001610152.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001610153.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001610154.1 InterPro; Glutathione S-transferase C-terminal; hypothetical protein YP_001610155.1 dihydrodipicolinate reductase (EC 1.3.1.26); catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001610156.1 catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001610158.1 homolog of MccC protein on Escherichia coli pMccC51 plasmid (CAD32229.1); hypothetical protein YP_001610161.1 Homologous to hypothetical protein BH12550 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610162.1 Drug resistance transporter Bcr/CflA family,InterPro; Major facilitator superfamily; hypothetical protein YP_001610166.1 homologous to PUTATIVE TRANSPORT TRANSMEMBRANE PROTEIN [Ralstonia solanacearum GMI1000],InterPro; Major facilitator superfamily; hypothetical protein YP_001610172.1 similar to membrane protein, putative [Bacillus anthracis str. 'Ames Ancestor'],InterPro; Major facilitator superfamily; hypothetical protein YP_001610175.1 Similar to COG2189: Adenine specific DNA methylase Mod [Clostridium thermocellum ATCC 27405]; similar to type III restriction-modification system StyLTI enzyme mod (StyLTI methyltransferase) (M.StyLTI) (P40814),InterPro; DNA methylase N-4/N-6; hypothetical protein YP_001610176.1 Similar to type III restriction system endonuclease [Burkholderia pseudomallei K96243]; similar to type III restriction-modification system EcoPI enzyme res (P08764),InterPro; Type III restriction enzyme res subunit; hypothetical protein YP_001610178.1 Fragment homologous to hypothetical protein BH13090 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610180.1 homologous to sensor histidine kinase [Brucella abortus biovar 1 str. 9-941],InterPro; Histidine kinase; hypothetical protein YP_001610181.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001610183.1 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media YP_001610185.1 Related to LIPOPROTEIN VSAG (FRAGMENT) [Mycoplasma pulmonis UAB CTIP],InterPro; Proline-rich region; hypothetical protein YP_001610188.1 Homolog of hypothetical protein BH13890 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610189.1 Homolog of hypothetical protein BH13920 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610199.1 partly similar to portal protein (Protein gp1) of bacteriophage P22 (P26744); hypothetical protein YP_001610200.1 homologous to terminase [Zymomonas mobilis subsp. mobilis ZM4]; hypothetical protein YP_001610204.1 Chaperone clpB (Heat-shock protein F84.1) (P63284 in E. coli),InterPro; AAA ATPase central region; hypothetical protein YP_001610213.1 similar to hypothetical UPF0243 zinc-binding protein BMEI1673 of Brucella melitensis (P67479); hypothetical protein YP_001610214.1 partially similar to hypothetical UPF0243 zinc-binding protein BMEI1673 of Brucella melitensis (P67479),InterPro; Protein of unknown function DUF329; hypothetical protein YP_001610216.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001610217.1 partially homologous to transcriptional regulator BH14970 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610219.1 Homolog of hypothetical protein BH14190 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610220.1 Homolog of phosphoribosylaminoimidazole carboxylase I [Bartonella henselae str. Houston-1],InterPro; 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; hypothetical protein YP_001610221.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001610222.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_001610223.1 hypothetical protein with predicted Tetratricopeptide repeats (TPR) and signal peptide,InterPro: TPR repeat; hypothetical protein YP_001610224.1 N-terminal fragment of Btr_2060; hypothetical protein YP_001610225.1 N-terminal fragment of Btr_2060; hypothetical protein YP_001610232.1 similar to hypothetical protein MG246 of Mycoplasma genitalium (P47488),InterPro; Conserved hypothetical protein 282; hypothetical protein YP_001610242.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001610243.1 Homologous to hypothetical protein BH14430 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610245.1 homologous to BH14460 and BQ11430; hypothetical protein YP_001610246.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610247.1 InterPro: Helix-turn-helix motif; hypothetical protein YP_001610250.1 hypothetical protein with predicted TMH (six); hypothetical protein YP_001610252.1 InterPro; Electron transfer flavoprotein alpha subunit; hypothetical protein YP_001610253.1 homologous to BQ11530; hypothetical protein YP_001610254.1 homologous to BQ11530; hypothetical protein YP_001610257.1 hypothetical protein with predicted signal peptide; hypothetical protein YP_001610258.1 partial similarity to permeases of the major facilitator superfamily; hypothetical protein YP_001610260.1 predicted integral membrane protein; hypothetical protein YP_001610262.1 homologous to YopJ of Yersinia pseudotuberculosis (P31498) and to Yop effector YopP [Yersinia enterocolitica],InterPro; Peptidase C55; hypothetical protein YP_001610263.1 homologous to YopJ of Yersinia pseudotuberculosis (P31498) and to Yop effector YopP [Yersinia enterocolitica],InterPro; Peptidase C55; hypothetical protein YP_001610264.1 homologous to YopJ of Yersinia pseudotuberculosis (P31498) and to Yop effector YopP [Yersinia enterocolitica],InterPro; Peptidase C55; hypothetical protein YP_001610268.1 weakly similar to hypothetical UPF0026 protein MJ0257 of Methanococcus jannaschii (Q57705); hypothetical protein YP_001610269.1 hypothetical protein with predicted TMH (eleven);,partial similarity to quinolone resistance protein norA of Staphylococcus aureus (P0A0J4) (integral membrane protein, belongs to the major facilitator superfamily, putative active efflux pump of hydrophilic quinolones); hypothetical protein YP_001610270.1 putative P4-family integrase; hypothetical protein YP_001610271.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001610272.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001610273.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001610278.1 similar to ATPase family protein [Treponema denticola ATCC 35405]; hypothetical protein YP_001610283.1 weakly similar to COG5295: Autotransporter adhesin [Haemophilus somnus 129PT];,weakly similar to Laminin gamma-2 chain precursor (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit) (Q13753 in Human) ,InterPro; Bacterial chemotaxis sensory transducer; hypothetical protein YP_001610284.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610289.1 homologous to hypothetical genomic island protein BH09290 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610290.1 partly similar to hypothetical genomic island protein BH09300 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610291.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610295.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1];,homologous to hypothetical protein HI1419 of Haemophilus influenzae (P44190); hypothetical protein YP_001610299.1 homologous to expressed protein [Bartonella henselae str. Houston-1];,homologous to gp54 [Burkholderia cepacia phage Bcep22]; hypothetical protein YP_001610301.1 similar to portal protein (Protein gp1) of Bacteriophage P22 (P26744); hypothetical protein YP_001610302.1 similar to terminase large subunit of Bacteriophage SPP1 (G2P) (P54308); hypothetical protein YP_001610305.1 Single-strand binding protein (SSB) (Helix-destabilizing protein) (Q8YHC2 in Brucella melitensis),InterPro; Single-strand binding protein; hypothetical protein YP_001610306.1 partially similar to hypothetical protein HI1412 of Haemophilus influenzae (P45197); hypothetical protein YP_001610309.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1] and to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610310.1 homologous to hypothetical prophage protein [Bartonella henselae str. Houston-1] and to hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610312.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610313.1 similar to hypothetical prophage protein BH03620 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610315.1 homologous to BH07740; hypothetical protein YP_001610317.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1] and to hypothetical prophage protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610318.1 phage anti-repressor protein;,partially similar to Hypothetical protein HI1422 of Haemophilus influenzae (P44193); hypothetical protein YP_001610319.1 homologous to hypothetical protein ydcK of E. coli (P76100);,homologous to orf229 gp [Streptococcus thermophilus bacteriophage Sfi19],InterPro: Bacterial transferase hexapeptide repeat; hypothetical protein YP_001610320.1 partly homologous to recombination protein bet of bacteriophage Lambda (P03698),InterPro; RecT protein; hypothetical protein YP_001610323.1 Prophage P4 integrase (Int(P4)),InterPro; Phage integrase; hypothetical protein YP_001610324.1 similar to hypothetical protein HI0703 homolog of Haemophilus somnus (P36684); hypothetical protein YP_001610325.1 homologous to hypothetical disulfide bond formation protein B [Brucella abortus biovar 1 str. 9-941],InterPro; Disulfide bond formation protein DsbB; hypothetical protein YP_001610328.1 partly similar to HYPOTHETICAL PROTEIN [Sinorhizobium meliloti]; hypothetical protein YP_001610329.1 InterPro; Protein of unknown function DUF125; hypothetical protein YP_001610330.1 catalyzes the formation of dUMP from dUTP YP_001610333.1 integrase fragment; hypothetical protein YP_001610334.1 Biopolymer transport exbD protein,InterPro; Biopolymer transport protein ExbD/TolR; hypothetical protein YP_001610335.1 Biopolymer transport exbB protein,InterPro; MotA/TolQ/ExbB proton channel; hypothetical protein YP_001610338.1 Micrococcal nuclease (thermonuclease) homologs (COG1525); hypothetical protein YP_001610339.1 VirB2-like protein precursor, component of type IV secretion system; hypothetical protein YP_001610340.1 VirB3-like protein, homologous to VirB3 protein of Agrobacterium tumefaciens (P0A3V9), component of type IV secretion system,InterPro; Type IV secretory pathway VirB3-like; hypothetical protein YP_001610343.1 VirB5-like protein precursor, homologous to VirB5 type IV secretion protein of Sinorhizobium meliloti 1021 (&&&gb|AAK65373.1|); hypothetical protein YP_001610345.1 VirB6-like protein, homologous to VirB6 of Bartonella tribocorum (&&&emb|CAC51481.1|),InterPro; TrbL/VirB6 plasmid conjugal transfer protein; hypothetical protein YP_001610346.1 VirB6-like protein, homologous to VirB6 of Bartonella tribocorum (&&&emb|CAC51481.1|),InterPro; TrbL/VirB6 plasmid conjugal transfer protein; hypothetical protein YP_001610347.1 VirB7-like protein precursor, Lipo-protein precursor; hypothetical protein YP_001610348.1 VirB8-like protein, homologue of VirB8 from Agrobacterium tumefaciens (P09781),InterPro; VirB8; hypothetical protein YP_001610349.1 VirB9-like protein precursor, homologous to VirB9 from Agrobacterium tumefaciens (P0A3W6),InterPro; Type IV secretion system CagX conjugation protein; hypothetical protein YP_001610350.1 VirB10-like protein, homologous to VirB10 of Sinorhizobium meliloti (&&&ref|NP_435956.1|),InterPro; Bacterial conjugation TrbI-like protein; hypothetical protein YP_001610351.1 VirB11-like protein, homologous to VirB11 of Bartonella henselae [KO:K03196]; hypothetical protein YP_001610356.1 homologous to cell filamentation protein fic of E. coli (P20605),InterPro; Filamentation induced by cAMP protein Fic; hypothetical protein YP_001610359.1 repeated end of previous gene (mrsA, Btr_2355); hypothetical protein YP_001610360.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001610364.1 Outer membrane lipoprotein omp16/pal precursor (Minor outer membrane protein omp16) (16-kDa OMP) (16.5-kDa minor OMP) (P0A3S9 in Brucella abortus),InterPro; OmpA/MotB domain; hypothetical protein YP_001610366.1 InterPro; Protein of unknown function DUF28; hypothetical protein YP_001610369.1 putative P4-family integrase; hypothetical protein YP_001610370.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001610373.1 TolQ protein (involved in the tonB-independent uptake of proteins) (P50598 in Pseudomonas aeruginosa) ,InterPro; MotA/TolQ/ExbB proton channel; hypothetical protein YP_001610374.1 putative thioesterase,InterPro; 4-hydroxybenzoyl-CoA thioesterase; hypothetical protein YP_001610375.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001610376.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001610377.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001610378.1 similar to probable transcriptional regulator, AraC family [Rhodopseudomonas palustris CGA009]; hypothetical protein YP_001610380.1 catalyzes the formation of thiamine monophosphate from 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate and 4-methyl-5-(2-phosphono-oxyethyl)-thiazole YP_001610386.1 hypothetical protein with predicted signal peptide; hypothetical protein YP_001610392.1 hypothetical protein with predicted signal peptide; hypothetical protein YP_001610393.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001610400.1 homologous to lipid A export ATP-binding/permease msbA of Escherichia coli O6 (Q8FJB1)),InterPro; ABC transporter transmembrane region; hypothetical protein YP_001610401.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001610405.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001610407.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001610409.1 InterPro; Protein of unknown function DUF710; hypothetical protein YP_001610413.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001610418.1 InterPro: ABC transporter; hypothetical protein YP_001610421.1 homology to ZINC METALLOPROTEASE [Brucella melitensis 16M],InterPro; Peptidase M48; hypothetical protein YP_001610422.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production YP_001610423.1 partial homology to ATP-dependent helicase [Brucella abortus biovar 1 str. 9-941]; hypothetical protein YP_001610424.1 Ferredoxin II (FdII),InterPro; 4Fe-4S ferredoxin iron-sulfur binding domain; hypothetical protein YP_001610425.1 InterPro; Transcription factor CarD; hypothetical protein YP_001610428.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001610430.1 hypothetical protein with predicted signal peptide; hypothetical protein YP_001610431.1 putative permease of the major facilitator superfamily,InterPro; Major facilitator superfamily; hypothetical protein YP_001610432.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001610435.1 putative permease of the major facilitator superfamily (Mfs); hypothetical protein YP_001610437.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001610438.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001610439.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001610440.1 InterPro; H+-transporting two-sector ATPase delta (OSCP) subunit; hypothetical protein YP_001610442.1 yacA fragment; hypothetical protein YP_001610444.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001610446.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_001610448.1 leucyl-tRNA synthetase (EC 6.1.1.4); leucine--tRNA ligase); leucyl-tRNA synthetase bacterial/mitochondrial class Ia; leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001610449.1 nterPro: Protein of unknown function UPF0001; hypothetical protein YP_001610451.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001610452.1 Cell division ATP-binding protein FtsE,InterPro: ABC transporter; hypothetical protein YP_001610455.1 InterPro; DEAD/DEAH box helicase; hypothetical protein YP_001610456.1 homologous to macrolide-specific ABC-type efflux carrier MacB of Escherichia coli (P75831),InterPro: ABC transporter; hypothetical protein YP_001610457.1 homologous to macrolide-specific efflux protein macA precursor of Escherichia coli (P75830) and to putative HlyD family (ABC efflux pump associated) secretion protein [Yersinia pseudotuberculosis IP 32953]; hypothetical protein YP_001610458.1 similarity to multidrug efflux MFS outer membrane protein (RND family) of Legionella pneumophila and to nodulation protein T precursor of Rhizobium leguminosarum; ,InterPro; Outer membrane efflux protein; hypothetical protein YP_001610461.1 homology to putative prophage CPS-53 integrase of E.coli(P37326);P4-family integrase; hypothetical protein YP_001610462.1 InterPro; Cell divisionFtsK/SpoIIIE protein; hypothetical protein YP_001610464.1 KorA/KorB, repressor system of the trw locus; hypothetical protein YP_001610466.1 Component of type IV secretion system; hypothetical protein YP_001610467.1 toxin-antitoxin system;,weak similarity to KorA [IncN plasmid R46] korA protein -Escherichia coli plasmid pKM101; hypothetical protein YP_001610468.1 Component of type IV secretion system; hypothetical protein YP_001610469.1 Component of type IV secretion system; hypothetical protein YP_001610470.1 Component of type IV secretion system; hypothetical protein YP_001610471.1 Component of type IV secretion system; hypothetical protein YP_001610472.1 Component of type IV secretion system; hypothetical protein YP_001610473.1 Component of type IV secretion system; hypothetical protein YP_001610474.1 Component of type IV secretion system; hypothetical protein YP_001610475.1 Component of type IV secretion system,InterPro; Type IV secretory pathway VirB3-like; hypothetical protein YP_001610476.1 Component of type IV secretion system,InterPro; CagE TrbE VirB family component of type IV transporter system; hypothetical protein YP_001610477.1 Component of type IV secretion system; hypothetical protein YP_001610478.1 Component of type IV secretion system; hypothetical protein YP_001610479.1 Component of type IV secretion system; hypothetical protein YP_001610480.1 Component of type IV secretion system; hypothetical protein YP_001610481.1 Component of type IV secretion system,InterPro; TrbL/VirB6 plasmid conjugal transfer protein; hypothetical protein YP_001610482.1 Component of type IV secretion system; hypothetical protein YP_001610483.1 Component of type IV secretion system; hypothetical protein YP_001610484.1 Component of type IV secretion system,InterPro; TrbL/VirB6 plasmid conjugal transfer protein; hypothetical protein YP_001610485.1 Component of type IV secretion system; hypothetical protein YP_001610486.1 Component of type IV secretion system,InterPro; TrbL/VirB6 plasmid conjugal transfer protein; hypothetical protein YP_001610487.1 Component of type IV secretion system; hypothetical protein YP_001610488.1 Component of type IV secretion system,InterPro; Proline-rich region; hypothetical protein YP_001610489.1 Component of type IV secretion system,InterPro; TrbL/VirB6 plasmid conjugal transfer protein; hypothetical protein YP_001610490.1 Component of type IV secretion system; hypothetical protein YP_001610491.1 Component of type IV secretion system,InterPro; VirB8; hypothetical protein YP_001610492.1 Component of type IV secretion system,InterPro; Type IV secretion system CagX conjugation protein; hypothetical protein YP_001610493.1 Component of type IV secretion system,InterPro; Bacterial conjugation TrbI-like protein; hypothetical protein YP_001610494.1 Component of type IV secretion system,InterPro; Bacterial type II secretion system protein E; hypothetical protein YP_001610497.1 hypothetical genomic island protein [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610498.1 hypothetical genomic island protein, DEP domain containing protein; hypothetical protein YP_001610501.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001610502.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001610503.1 Succinate dehydrogenase hydrophobic membrane anchor protein [KO:K00242],InterPro; Succinate dehydrogenase cytochrome b subunit; hypothetical protein YP_001610504.1 Succinate dehydrogenase cytochrome b556 subunit (Cytochrome b-556)[KO:K00241],InterPro; Succinate dehydrogenase cytochrome b subunit; hypothetical protein YP_001610505.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001610506.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001610507.1 Essential for efficient processing of 16S rRNA YP_001610509.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001610510.1 UV-induced protein uvi31 (Q12238) ,InterPro; BolA-like protein; hypothetical protein YP_001610511.1 InterPro; Heat shock protein DnaJ N-terminal; hypothetical protein YP_001610512.1 Homologous to aerobic cobaltochelatase cobS subunit (P29933),hydrogenobyrinic acid ac-diamide cobaltochelatase cobS subunit,InterPro; Cobalt chelatase pCobS small subunit; hypothetical protein YP_001610513.1 Aerobic cobaltochelatase cobT subunit (P29934),hydrogenobyrinic acid ac-diamide cobaltochelatase cobT subunit,InterPro: Cobalt chelatase pCobT subunit; hypothetical protein YP_001610514.1 conserved hypothetical protein with predicted TMH (six) and a signal peptide,InterPro; Protein of unknown function DUF165; hypothetical protein YP_001610515.1 required for 70S ribosome assembly YP_001610516.1 conserved hypothetical protein with predicted TMH (two) and a signal peptide;,similar to Surfeit locus protein SurF1 in mouse (P09925),InterPro; Surf1 protein; hypothetical protein YP_001610517.1 involved in de novo purine biosynthesis YP_001610519.1 integrase fragment; hypothetical protein YP_001610522.1 putative metalloprotease YP_001610523.1 InterPro; Sel1-like repeat; hypothetical protein YP_001610524.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001610525.1 catalyzes the interconversion of chorismate to prephenate YP_001610526.1 Signal recognition particle protein (Fifty-four homolog) (O33013 in Mycobacterium leprae),InterPro; Signal recognition particle protein; hypothetical protein YP_001610527.1 carbonic anhydrase 1 (EC 4.2.1.1) YP_001610528.1 homologous to NAD-specific glutamate dehydrogenase [Vibrio vulnificus YJ016],InterPro; Bacterial NAD-glutamate dehydrogenase; hypothetical protein YP_001610530.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_001610533.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001610534.1 InterPro; Protein of unknown function DUF589; hypothetical protein YP_001610535.1 homologous to two component response regulator MtrA,InterPro; Response regulator receiver; hypothetical protein YP_001610536.1 homology SAM-dependent methyltransferases,InterPro; Generic methyltransferase; hypothetical protein YP_001610537.1 hypothetical transmembrane protein; hypothetical protein YP_001610538.1 diaminopimelate decarboxylase (EC 4.1.1.20) YP_001610540.1 argininosuccinate lyase (EC 4.3.2.1); delta crystallin hypothetical protein; catalyzes the formation of arginine from (N-L-arginino)succinate YP_001610541.1 Thiol:disulfide interchange protein tlpA (Cytochrome c biogenesis protein tlpA),InterPro; Thioredoxin domain 2; hypothetical protein YP_001610544.1 dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate YP_001610545.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA YP_001610546.1 InterPro: ABC transporter; hypothetical protein YP_001610547.1 homology to permease of branched-chain amino acid ABC transporter system of Brucella suis,InterPro; Bacterial inner-membrane translocator; hypothetical protein YP_001610548.1 InterPro; Protein of unknown function DUF534; hypothetical protein YP_001610549.1 similar to Dam modification methylase [Bacteriophage B3],InterPro: N6 adenine-specific DNA methyltransferase D12 class,InterPro; N6 adenine-specific DNA methyltransferase D12 class; hypothetical protein YP_001610550.1 homologous to late control gene D protein (GpD) of Bacteriophage 186 (P21679); hypothetical protein YP_001610551.1 putative phage-tail protein; hypothetical protein YP_001610553.1 similar to prophage P2W3, tail tape measure protein [Wolbachia endosymbiont of Drosophila melanogaster]; hypothetical protein YP_001610555.1 partly similar to hypothetical genomic island protein BH07900 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610556.1 homologous to hypothetical genomic island protein [Bartonella henselae str. Houston-1];,weak similarity to major tail tube protein FII [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610557.1 major tail sheath protein FI,homologous to major tail sheath protein (Protein FI) of Bacteriophage P2 (P22501),InterPro; Phage tail sheath protein; hypothetical protein YP_001610562.1 phage protein gp26; baseplate assembly protein J (GpJ),InterPro; Baseplate J-like protein; hypothetical protein YP_001610563.1 weak homology to phage protein gp25 [Bartonella henselae str. Houston-1]; baseplate assembly protein W (GpW),InterPro; GPW/gp25 family; hypothetical protein YP_001610565.1 weak homology to gp24, phage-related baseplate assembly protein [Bartonella henselae str. Houston-1]; baseplate assembly protein V (GpV); hypothetical protein YP_001610567.1 similar to Mu-like prophage FluMu protein gp36 (P44230),InterPro; Phage virion morphogenesis (putative tail completion) protein; hypothetical protein YP_001610568.1 similar to Mu-like prophage FluMu protein gp36 (P44230); hypothetical protein YP_001610569.1 similar to capsid protein [Bacteriophage B3]; hypothetical protein YP_001610570.1 weak similarity to hypothetical protein B3ORF37 [Bacteriophage B3]; hypothetical protein YP_001610571.1 similar to prophage MuSo2, protein Gp32, putative [Shewanella oneidensis MR-1]; hypothetical protein YP_001610572.1 similar to hypothetical protein [Escherichia coli O157:H7];,similar to F protein (gpF) (Protein gp30) of bacteriophage Mu (Q01259),InterPro; Phage putativehead morphogenesis protein SPP1 gp7; hypothetical protein YP_001610573.1 Mu-like prophage FluMu protein gp29; hypothetical protein YP_001610574.1 Mu-like prophage FluMu protein gp28; hypothetical protein YP_001610575.1 Mu-like prophage FluMu protein gp27; hypothetical protein YP_001610576.1 weak similarity to hypothetical protein gp26 of Bacteriophage Mu; hypothetical protein YP_001610578.1 hypothetical protein with predicted signal peptide; hypothetical protein YP_001610579.1 hypothetical protein with predicted signal peptide; hypothetical protein YP_001610580.1 similar to glycosidase [Bacteriophage 11b]; hypothetical protein YP_001610582.1 similar to Mu-like prophage FluMu protein gp16 (P71387); hypothetical protein YP_001610583.1 similar to gp05 [Burkholderia cenocepacia phage BcepMu]; hypothetical protein YP_001610586.1 Mu-like prophage FluMu DNA transposition protein B; hypothetical protein YP_001610587.1 Transposase; similar to Mu-like prophage FluMu transposase A of Haemophilus influenzae (O05069) ,InterPro; Bacteriophage Mu transposase; hypothetical protein YP_001610590.1 homologous to hypothetical genomic island protein BH09130 [Bartonella henselae str. Houston-1]; hypothetical protein YP_001610591.1 similar to Mu-like prophage FluMu DNA-binding protein Ner (P46496); hypothetical protein YP_001610593.1 InterPro; GCN5-related N-acetyltransferase; hypothetical protein YP_001610599.1 homologous to hypothetical protein yjiA of E. coli (P24203);,homologous to cobalamin synthesis protein/P47K family protein [Brucella abortus biovar 1 str. 9-941],InterPro; Cobalamin synthesis protein/P47K; hypothetical protein YP_001610601.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001610602.1 similar to tyrosine recombinase xerD of Yersinia pestis (P24167),InterPro; Phage integrase; hypothetical protein YP_001610603.1 shikimate kinase I (EC 2.7.1.71); catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001610604.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001610607.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001610608.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001610609.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001610610.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001610611.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001610612.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+ YP_001610614.1 InterPro; Orn/DAP/Arg decarboxylase 2; hypothetical protein YP_001610616.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001610617.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001610618.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001610619.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001610620.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001610621.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_001610622.1 similar to hypothetical protein yhcM of E. coli (P64612); ,similar to AFG1 protein of yeast (P32317) ,InterPro; AFG1-like ATPase; hypothetical protein YP_001610623.1 Outer membrane lipoprotein omp19 homolog precursor (Q98EC1 in Sinorhizobium meliloti); hypothetical protein YP_001610624.1 diaminopimelate epimerase (EC 5.1.1.7); involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001610626.1 Cell division protein, ftsY homolog (P44870 in Haemophilus influenzae),InterPro; Cell division transporter substrate-binding protein FtsY; hypothetical protein YP_001610627.1 Involved in cell division; probably involved in intracellular septation YP_001610630.1 hypothetical protein with predicted signal peptide; hypothetical protein YP_001610631.1 Chromosome partitioning protein parB (O05190 in Caulobacter crescentus),InterPro; ParB-like partition protein; hypothetical protein YP_001610632.1 Chromosome partitioning protein parA (O05189 in Caulobacter crescentus),InterPro: ATPase ParA type; hypothetical protein YP_001610633.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001610634.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001610635.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001610636.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes